ORF_ID e_value Gene_name EC_number CAZy COGs Description
PBLMHBDN_00001 2.3e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PBLMHBDN_00002 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PBLMHBDN_00003 2.4e-33 yaaA S S4 domain
PBLMHBDN_00004 1.6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PBLMHBDN_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
PBLMHBDN_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PBLMHBDN_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PBLMHBDN_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
PBLMHBDN_00011 4.4e-183 yaaC S YaaC-like Protein
PBLMHBDN_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PBLMHBDN_00013 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PBLMHBDN_00014 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PBLMHBDN_00015 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PBLMHBDN_00016 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PBLMHBDN_00017 4.3e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PBLMHBDN_00018 1.3e-09
PBLMHBDN_00019 4.5e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
PBLMHBDN_00020 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
PBLMHBDN_00021 3.8e-211 yaaH M Glycoside Hydrolase Family
PBLMHBDN_00022 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
PBLMHBDN_00023 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PBLMHBDN_00024 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PBLMHBDN_00025 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PBLMHBDN_00026 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PBLMHBDN_00027 3.6e-32 yaaL S Protein of unknown function (DUF2508)
PBLMHBDN_00028 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
PBLMHBDN_00029 3.4e-39 S COG NOG14552 non supervised orthologous group
PBLMHBDN_00032 3.8e-30 csfB S Inhibitor of sigma-G Gin
PBLMHBDN_00033 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PBLMHBDN_00034 1e-188 yaaN P Belongs to the TelA family
PBLMHBDN_00035 4.9e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
PBLMHBDN_00036 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PBLMHBDN_00037 7.5e-55 yaaQ S protein conserved in bacteria
PBLMHBDN_00038 1.2e-71 yaaR S protein conserved in bacteria
PBLMHBDN_00039 1.3e-182 holB 2.7.7.7 L DNA polymerase III
PBLMHBDN_00040 8.8e-145 yaaT S stage 0 sporulation protein
PBLMHBDN_00041 7.7e-37 yabA L Involved in initiation control of chromosome replication
PBLMHBDN_00042 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
PBLMHBDN_00043 4.7e-48 yazA L endonuclease containing a URI domain
PBLMHBDN_00044 3.5e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PBLMHBDN_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
PBLMHBDN_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBLMHBDN_00047 3.4e-143 tatD L hydrolase, TatD
PBLMHBDN_00048 2.9e-230 rpfB GH23 T protein conserved in bacteria
PBLMHBDN_00049 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PBLMHBDN_00050 1.1e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PBLMHBDN_00051 8.4e-146 yabG S peptidase
PBLMHBDN_00052 7.8e-39 veg S protein conserved in bacteria
PBLMHBDN_00053 2.9e-27 sspF S DNA topological change
PBLMHBDN_00054 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PBLMHBDN_00055 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PBLMHBDN_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
PBLMHBDN_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PBLMHBDN_00058 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PBLMHBDN_00059 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PBLMHBDN_00060 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PBLMHBDN_00061 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PBLMHBDN_00062 3.7e-40 yabK S Peptide ABC transporter permease
PBLMHBDN_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PBLMHBDN_00064 6.2e-91 spoVT K stage V sporulation protein
PBLMHBDN_00065 2.3e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PBLMHBDN_00066 1.2e-272 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PBLMHBDN_00067 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PBLMHBDN_00068 1.9e-49 yabP S Sporulation protein YabP
PBLMHBDN_00069 2.9e-103 yabQ S spore cortex biosynthesis protein
PBLMHBDN_00070 7.1e-33 divIC D Septum formation initiator
PBLMHBDN_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
PBLMHBDN_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
PBLMHBDN_00075 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
PBLMHBDN_00076 1.4e-184 KLT serine threonine protein kinase
PBLMHBDN_00077 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PBLMHBDN_00078 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PBLMHBDN_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PBLMHBDN_00080 7.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PBLMHBDN_00081 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PBLMHBDN_00082 3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
PBLMHBDN_00083 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PBLMHBDN_00084 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PBLMHBDN_00085 9.8e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
PBLMHBDN_00086 5e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
PBLMHBDN_00087 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PBLMHBDN_00088 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PBLMHBDN_00089 2.2e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PBLMHBDN_00090 4.5e-29 yazB K transcriptional
PBLMHBDN_00091 7.8e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PBLMHBDN_00092 3.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PBLMHBDN_00093 3.4e-39 S COG NOG14552 non supervised orthologous group
PBLMHBDN_00095 1.3e-07
PBLMHBDN_00098 2e-08
PBLMHBDN_00103 3.4e-39 S COG NOG14552 non supervised orthologous group
PBLMHBDN_00104 7.5e-77 ctsR K Belongs to the CtsR family
PBLMHBDN_00105 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
PBLMHBDN_00106 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PBLMHBDN_00107 0.0 clpC O Belongs to the ClpA ClpB family
PBLMHBDN_00108 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PBLMHBDN_00109 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PBLMHBDN_00110 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
PBLMHBDN_00111 2.7e-123 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PBLMHBDN_00112 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PBLMHBDN_00113 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBLMHBDN_00114 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
PBLMHBDN_00115 6.2e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PBLMHBDN_00116 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PBLMHBDN_00117 1.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBLMHBDN_00118 4.2e-89 yacP S RNA-binding protein containing a PIN domain
PBLMHBDN_00119 8.9e-116 sigH K Belongs to the sigma-70 factor family
PBLMHBDN_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PBLMHBDN_00121 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
PBLMHBDN_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PBLMHBDN_00123 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PBLMHBDN_00124 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PBLMHBDN_00125 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PBLMHBDN_00126 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
PBLMHBDN_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PBLMHBDN_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PBLMHBDN_00129 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
PBLMHBDN_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PBLMHBDN_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PBLMHBDN_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PBLMHBDN_00133 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PBLMHBDN_00134 5.6e-183 ybaC 3.4.11.5 S Alpha/beta hydrolase family
PBLMHBDN_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PBLMHBDN_00136 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PBLMHBDN_00137 3e-105 rplD J Forms part of the polypeptide exit tunnel
PBLMHBDN_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PBLMHBDN_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PBLMHBDN_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PBLMHBDN_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PBLMHBDN_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PBLMHBDN_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PBLMHBDN_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
PBLMHBDN_00145 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PBLMHBDN_00146 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PBLMHBDN_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PBLMHBDN_00148 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PBLMHBDN_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PBLMHBDN_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PBLMHBDN_00151 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PBLMHBDN_00152 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PBLMHBDN_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PBLMHBDN_00154 1.9e-23 rpmD J Ribosomal protein L30
PBLMHBDN_00155 4.1e-72 rplO J binds to the 23S rRNA
PBLMHBDN_00156 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PBLMHBDN_00157 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PBLMHBDN_00158 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
PBLMHBDN_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PBLMHBDN_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PBLMHBDN_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PBLMHBDN_00162 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PBLMHBDN_00163 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PBLMHBDN_00164 4.7e-58 rplQ J Ribosomal protein L17
PBLMHBDN_00165 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PBLMHBDN_00166 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PBLMHBDN_00167 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PBLMHBDN_00168 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PBLMHBDN_00169 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PBLMHBDN_00170 6.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
PBLMHBDN_00171 6.9e-144 ybaJ Q Methyltransferase domain
PBLMHBDN_00172 1.4e-81 yizA S Damage-inducible protein DinB
PBLMHBDN_00173 1.4e-77 ybaK S Protein of unknown function (DUF2521)
PBLMHBDN_00174 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PBLMHBDN_00175 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PBLMHBDN_00176 1.7e-75 gerD
PBLMHBDN_00177 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
PBLMHBDN_00178 1.8e-131 pdaB 3.5.1.104 G Polysaccharide deacetylase
PBLMHBDN_00179 3.4e-39 S COG NOG14552 non supervised orthologous group
PBLMHBDN_00182 2e-08
PBLMHBDN_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
PBLMHBDN_00186 2.1e-219 glcP G Major Facilitator Superfamily
PBLMHBDN_00187 2.1e-246 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PBLMHBDN_00188 1.4e-175 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
PBLMHBDN_00189 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
PBLMHBDN_00190 6.7e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
PBLMHBDN_00191 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
PBLMHBDN_00192 6e-108 ybbA S Putative esterase
PBLMHBDN_00193 6.1e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBLMHBDN_00194 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBLMHBDN_00195 7.5e-172 feuA P Iron-uptake system-binding protein
PBLMHBDN_00196 1.1e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
PBLMHBDN_00197 8.6e-237 ybbC 3.2.1.52 S protein conserved in bacteria
PBLMHBDN_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
PBLMHBDN_00199 5.8e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
PBLMHBDN_00200 1.6e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PBLMHBDN_00201 9.2e-159 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PBLMHBDN_00202 7.7e-85 ybbJ J acetyltransferase
PBLMHBDN_00203 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
PBLMHBDN_00209 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
PBLMHBDN_00210 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PBLMHBDN_00211 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PBLMHBDN_00212 1.3e-223 ybbR S protein conserved in bacteria
PBLMHBDN_00213 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PBLMHBDN_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PBLMHBDN_00215 1.1e-153 V ATPases associated with a variety of cellular activities
PBLMHBDN_00216 1.4e-105 S ABC-2 family transporter protein
PBLMHBDN_00217 3.6e-99 ybdN
PBLMHBDN_00218 2.4e-132 ybdO S Domain of unknown function (DUF4885)
PBLMHBDN_00219 2.1e-162 dkgB S Aldo/keto reductase family
PBLMHBDN_00220 2.9e-93 yxaC M effector of murein hydrolase
PBLMHBDN_00221 6.9e-52 S LrgA family
PBLMHBDN_00222 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
PBLMHBDN_00223 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
PBLMHBDN_00224 4.7e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PBLMHBDN_00225 2.7e-197 T COG4585 Signal transduction histidine kinase
PBLMHBDN_00226 1.2e-109 KT LuxR family transcriptional regulator
PBLMHBDN_00227 3e-165 V COG1131 ABC-type multidrug transport system, ATPase component
PBLMHBDN_00228 1.3e-202 V COG0842 ABC-type multidrug transport system, permease component
PBLMHBDN_00229 9.8e-195 V ABC-2 family transporter protein
PBLMHBDN_00230 9.2e-23
PBLMHBDN_00231 2.5e-75 S Domain of unknown function (DUF4879)
PBLMHBDN_00232 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
PBLMHBDN_00233 8e-107 yqeB
PBLMHBDN_00234 9.2e-40 ybyB
PBLMHBDN_00235 7.2e-292 ybeC E amino acid
PBLMHBDN_00236 3.7e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PBLMHBDN_00237 1.7e-259 glpT G -transporter
PBLMHBDN_00238 1.3e-16 S Protein of unknown function (DUF2651)
PBLMHBDN_00239 7.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
PBLMHBDN_00241 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
PBLMHBDN_00242 2e-31
PBLMHBDN_00243 1.2e-82 K Helix-turn-helix XRE-family like proteins
PBLMHBDN_00244 1.7e-196 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
PBLMHBDN_00245 1.5e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PBLMHBDN_00246 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PBLMHBDN_00247 2.1e-85 ybfM S SNARE associated Golgi protein
PBLMHBDN_00248 4.7e-151 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
PBLMHBDN_00249 6.1e-42 ybfN
PBLMHBDN_00250 5.6e-191 yceA S Belongs to the UPF0176 family
PBLMHBDN_00251 1.6e-214 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PBLMHBDN_00252 1.9e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PBLMHBDN_00253 1.5e-256 mmuP E amino acid
PBLMHBDN_00254 1.8e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
PBLMHBDN_00255 1.7e-257 agcS E Sodium alanine symporter
PBLMHBDN_00256 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
PBLMHBDN_00257 4.3e-207 phoQ 2.7.13.3 T Histidine kinase
PBLMHBDN_00258 4.8e-171 glnL T Regulator
PBLMHBDN_00259 1.9e-124 ycbJ S Macrolide 2'-phosphotransferase
PBLMHBDN_00260 1.8e-25 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
PBLMHBDN_00261 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PBLMHBDN_00262 4.5e-109 ydfN C nitroreductase
PBLMHBDN_00263 1.7e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
PBLMHBDN_00264 4.4e-62 mhqP S DoxX
PBLMHBDN_00265 2.4e-56 traF CO Thioredoxin
PBLMHBDN_00266 5.6e-62 ycbP S Protein of unknown function (DUF2512)
PBLMHBDN_00267 5.3e-77 sleB 3.5.1.28 M Cell wall
PBLMHBDN_00268 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
PBLMHBDN_00269 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PBLMHBDN_00270 9.2e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PBLMHBDN_00271 3.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PBLMHBDN_00272 7.9e-205 ycbU E Selenocysteine lyase
PBLMHBDN_00273 1e-241 lmrB EGP the major facilitator superfamily
PBLMHBDN_00274 6.5e-99 yxaF K Transcriptional regulator
PBLMHBDN_00275 2.5e-195 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PBLMHBDN_00276 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
PBLMHBDN_00277 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
PBLMHBDN_00278 4e-170 yccK C Aldo keto reductase
PBLMHBDN_00279 1.5e-175 ycdA S Domain of unknown function (DUF5105)
PBLMHBDN_00280 1.2e-255 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
PBLMHBDN_00281 2.8e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
PBLMHBDN_00282 5.8e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
PBLMHBDN_00283 1e-188 S response regulator aspartate phosphatase
PBLMHBDN_00284 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
PBLMHBDN_00285 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
PBLMHBDN_00286 2.3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
PBLMHBDN_00287 5.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PBLMHBDN_00288 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PBLMHBDN_00289 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBLMHBDN_00290 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
PBLMHBDN_00291 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
PBLMHBDN_00292 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
PBLMHBDN_00293 9.7e-138 terC P Protein of unknown function (DUF475)
PBLMHBDN_00294 0.0 yceG S Putative component of 'biosynthetic module'
PBLMHBDN_00295 1.1e-192 yceH P Belongs to the TelA family
PBLMHBDN_00296 9e-215 naiP P Uncharacterised MFS-type transporter YbfB
PBLMHBDN_00297 3.9e-229 proV 3.6.3.32 E glycine betaine
PBLMHBDN_00298 4.8e-138 opuAB P glycine betaine
PBLMHBDN_00299 1.5e-163 opuAC E glycine betaine
PBLMHBDN_00300 9e-209 amhX S amidohydrolase
PBLMHBDN_00301 2.5e-227 ycgA S Membrane
PBLMHBDN_00302 1.5e-80 ycgB
PBLMHBDN_00303 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
PBLMHBDN_00304 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PBLMHBDN_00305 8.1e-261 mdr EGP Major facilitator Superfamily
PBLMHBDN_00306 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
PBLMHBDN_00307 4.7e-114 ycgF E Lysine exporter protein LysE YggA
PBLMHBDN_00308 2.9e-150 yqcI S YqcI/YcgG family
PBLMHBDN_00309 5.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
PBLMHBDN_00310 3.8e-113 ycgI S Domain of unknown function (DUF1989)
PBLMHBDN_00311 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PBLMHBDN_00313 3.6e-108 tmrB S AAA domain
PBLMHBDN_00314 5.6e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
PBLMHBDN_00315 4.1e-221 G COG0477 Permeases of the major facilitator superfamily
PBLMHBDN_00316 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PBLMHBDN_00317 6.5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
PBLMHBDN_00318 1.2e-143 ycgL S Predicted nucleotidyltransferase
PBLMHBDN_00319 8.7e-170 ycgM E Proline dehydrogenase
PBLMHBDN_00320 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
PBLMHBDN_00321 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBLMHBDN_00322 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
PBLMHBDN_00323 4.6e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PBLMHBDN_00324 9.2e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
PBLMHBDN_00325 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
PBLMHBDN_00326 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBLMHBDN_00327 4.6e-227 yciC S GTPases (G3E family)
PBLMHBDN_00328 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PBLMHBDN_00329 1.1e-72 yckC S membrane
PBLMHBDN_00330 1.3e-48 S Protein of unknown function (DUF2680)
PBLMHBDN_00331 9e-11 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PBLMHBDN_00332 1.5e-65 nin S Competence protein J (ComJ)
PBLMHBDN_00333 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
PBLMHBDN_00334 1.6e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
PBLMHBDN_00335 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
PBLMHBDN_00336 2.6e-61 hxlR K transcriptional
PBLMHBDN_00337 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_00338 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_00339 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
PBLMHBDN_00340 4.4e-140 srfAD Q thioesterase
PBLMHBDN_00341 3e-248 bamJ E Aminotransferase class I and II
PBLMHBDN_00342 1.9e-129 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
PBLMHBDN_00343 2.3e-108 yczE S membrane
PBLMHBDN_00344 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PBLMHBDN_00345 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
PBLMHBDN_00346 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PBLMHBDN_00347 3.9e-159 bsdA K LysR substrate binding domain
PBLMHBDN_00348 1.6e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PBLMHBDN_00349 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
PBLMHBDN_00350 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
PBLMHBDN_00351 1.1e-75 yclD
PBLMHBDN_00352 1.2e-269 dtpT E amino acid peptide transporter
PBLMHBDN_00353 2.9e-275 yclG M Pectate lyase superfamily protein
PBLMHBDN_00355 2.3e-293 gerKA EG Spore germination protein
PBLMHBDN_00356 1.5e-233 gerKC S spore germination
PBLMHBDN_00357 3.3e-195 gerKB F Spore germination protein
PBLMHBDN_00358 6.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBLMHBDN_00359 1.1e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PBLMHBDN_00360 1.1e-141 yxeM M Belongs to the bacterial solute-binding protein 3 family
PBLMHBDN_00361 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
PBLMHBDN_00362 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
PBLMHBDN_00363 1.4e-217 yxeP 3.5.1.47 E hydrolase activity
PBLMHBDN_00364 4.9e-254 yxeQ S MmgE/PrpD family
PBLMHBDN_00365 2.8e-120 yclH P ABC transporter
PBLMHBDN_00366 5.1e-233 yclI V ABC transporter (permease) YclI
PBLMHBDN_00367 1.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PBLMHBDN_00368 4.1e-259 T PhoQ Sensor
PBLMHBDN_00369 1.6e-80 S aspartate phosphatase
PBLMHBDN_00371 4.5e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
PBLMHBDN_00372 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBLMHBDN_00373 1e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBLMHBDN_00374 6.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
PBLMHBDN_00375 7.9e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
PBLMHBDN_00376 2.1e-247 ycnB EGP Major facilitator Superfamily
PBLMHBDN_00377 6.7e-151 ycnC K Transcriptional regulator
PBLMHBDN_00378 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
PBLMHBDN_00379 1e-44 ycnE S Monooxygenase
PBLMHBDN_00380 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
PBLMHBDN_00381 1.7e-260 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PBLMHBDN_00382 1.9e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PBLMHBDN_00383 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PBLMHBDN_00384 3.6e-149 glcU U Glucose uptake
PBLMHBDN_00385 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PBLMHBDN_00386 1.6e-95 ycnI S protein conserved in bacteria
PBLMHBDN_00387 1.1e-297 ycnJ P protein, homolog of Cu resistance protein CopC
PBLMHBDN_00388 9.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
PBLMHBDN_00389 1.6e-55
PBLMHBDN_00390 5.1e-225 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
PBLMHBDN_00391 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
PBLMHBDN_00392 1.3e-204 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
PBLMHBDN_00393 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
PBLMHBDN_00395 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PBLMHBDN_00396 1e-139 ycsF S Belongs to the UPF0271 (lamB) family
PBLMHBDN_00397 4.4e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
PBLMHBDN_00398 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
PBLMHBDN_00399 4.6e-137 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
PBLMHBDN_00400 3.2e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
PBLMHBDN_00401 9.8e-130 kipR K Transcriptional regulator
PBLMHBDN_00402 1.8e-116 ycsK E anatomical structure formation involved in morphogenesis
PBLMHBDN_00404 5.1e-56 yczJ S biosynthesis
PBLMHBDN_00405 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
PBLMHBDN_00406 3.7e-173 ydhF S Oxidoreductase
PBLMHBDN_00407 0.0 mtlR K transcriptional regulator, MtlR
PBLMHBDN_00408 2.1e-285 ydaB IQ acyl-CoA ligase
PBLMHBDN_00409 5.3e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PBLMHBDN_00410 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
PBLMHBDN_00411 1.6e-114 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PBLMHBDN_00412 6.8e-77 ydaG 1.4.3.5 S general stress protein
PBLMHBDN_00413 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PBLMHBDN_00414 1.3e-47 ydzA EGP Major facilitator Superfamily
PBLMHBDN_00415 4.3e-74 lrpC K Transcriptional regulator
PBLMHBDN_00416 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PBLMHBDN_00417 1.6e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
PBLMHBDN_00418 2.5e-147 ydaK T Diguanylate cyclase, GGDEF domain
PBLMHBDN_00419 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
PBLMHBDN_00420 7.2e-231 ydaM M Glycosyl transferase family group 2
PBLMHBDN_00421 0.0 ydaN S Bacterial cellulose synthase subunit
PBLMHBDN_00422 0.0 ydaO E amino acid
PBLMHBDN_00423 4.1e-72 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PBLMHBDN_00424 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PBLMHBDN_00425 5.3e-64 K acetyltransferase
PBLMHBDN_00426 2e-33 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PBLMHBDN_00427 7.7e-85 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PBLMHBDN_00428 6.3e-69
PBLMHBDN_00429 8.8e-23 S Histidine kinase
PBLMHBDN_00430 1.5e-172 S Histidine kinase
PBLMHBDN_00432 1.2e-11
PBLMHBDN_00434 8.5e-75
PBLMHBDN_00435 1.9e-96
PBLMHBDN_00436 1.8e-38
PBLMHBDN_00437 2.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
PBLMHBDN_00439 6.5e-34 ydaT
PBLMHBDN_00440 3.7e-72 yvaD S Family of unknown function (DUF5360)
PBLMHBDN_00441 7.8e-53 yvaE P Small Multidrug Resistance protein
PBLMHBDN_00442 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
PBLMHBDN_00444 2.2e-57 ydbB G Cupin domain
PBLMHBDN_00445 7.2e-59 ydbC S Domain of unknown function (DUF4937
PBLMHBDN_00446 2.7e-154 ydbD P Catalase
PBLMHBDN_00447 1.9e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PBLMHBDN_00448 3.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PBLMHBDN_00449 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
PBLMHBDN_00450 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PBLMHBDN_00451 4e-158 ydbI S AI-2E family transporter
PBLMHBDN_00452 6.1e-171 ydbJ V ABC transporter, ATP-binding protein
PBLMHBDN_00453 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PBLMHBDN_00454 4.6e-52 ydbL
PBLMHBDN_00455 2e-203 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
PBLMHBDN_00456 1.5e-10 S Fur-regulated basic protein B
PBLMHBDN_00457 5.8e-09 S Fur-regulated basic protein A
PBLMHBDN_00458 1.8e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PBLMHBDN_00459 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PBLMHBDN_00460 1.8e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PBLMHBDN_00461 3.8e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PBLMHBDN_00462 3.2e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PBLMHBDN_00463 1.3e-60 ydbS S Bacterial PH domain
PBLMHBDN_00464 2.9e-260 ydbT S Membrane
PBLMHBDN_00465 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
PBLMHBDN_00466 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PBLMHBDN_00467 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
PBLMHBDN_00468 5.8e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PBLMHBDN_00469 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PBLMHBDN_00470 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
PBLMHBDN_00471 6.1e-146 rsbR T Positive regulator of sigma-B
PBLMHBDN_00472 1.8e-57 rsbS T antagonist
PBLMHBDN_00473 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PBLMHBDN_00474 6.6e-187 rsbU 3.1.3.3 KT phosphatase
PBLMHBDN_00475 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
PBLMHBDN_00476 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PBLMHBDN_00477 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBLMHBDN_00478 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
PBLMHBDN_00479 0.0 yhgF K COG2183 Transcriptional accessory protein
PBLMHBDN_00480 1.7e-14
PBLMHBDN_00481 4.3e-58 ydcK S Belongs to the SprT family
PBLMHBDN_00489 1.1e-95 ywrO S Flavodoxin-like fold
PBLMHBDN_00490 2.6e-149 S Serine aminopeptidase, S33
PBLMHBDN_00491 3.8e-257 proP EGP Transporter
PBLMHBDN_00492 7.7e-137 I esterase
PBLMHBDN_00493 4.8e-46 ohrB O OsmC-like protein
PBLMHBDN_00494 1.4e-48 ohrR K Transcriptional regulator
PBLMHBDN_00495 2.2e-64 ywnA K Transcriptional regulator
PBLMHBDN_00496 4.2e-110 ywnB S NAD(P)H-binding
PBLMHBDN_00497 1.4e-30 cspL K Cold shock
PBLMHBDN_00498 9.2e-40 yrkD S protein conserved in bacteria
PBLMHBDN_00499 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
PBLMHBDN_00500 2.2e-17 P Rhodanese Homology Domain
PBLMHBDN_00501 5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
PBLMHBDN_00502 1.5e-200 yrkH P Rhodanese Homology Domain
PBLMHBDN_00503 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
PBLMHBDN_00504 3.6e-116 yrkJ S membrane transporter protein
PBLMHBDN_00505 3.7e-117 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PBLMHBDN_00506 1.1e-101 S Protein of unknown function (DUF2812)
PBLMHBDN_00507 2.4e-50 K Transcriptional regulator PadR-like family
PBLMHBDN_00508 2.6e-180 S Patatin-like phospholipase
PBLMHBDN_00509 1.2e-82 S DinB superfamily
PBLMHBDN_00510 2.5e-116 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
PBLMHBDN_00511 2.7e-67 K COG1802 Transcriptional regulators
PBLMHBDN_00512 1.7e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
PBLMHBDN_00513 2.2e-142 sdaC E Serine transporter
PBLMHBDN_00514 4.1e-164 E Peptidase dimerisation domain
PBLMHBDN_00515 1.7e-125 rhaS5 K helix_turn_helix, arabinose operon control protein
PBLMHBDN_00516 1.5e-175 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PBLMHBDN_00517 6.5e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PBLMHBDN_00518 7.5e-191 ydeG EGP Major facilitator superfamily
PBLMHBDN_00519 3.5e-28 3.6.1.55 F Belongs to the Nudix hydrolase family
PBLMHBDN_00522 6.6e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
PBLMHBDN_00523 1.2e-09 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PBLMHBDN_00524 8.4e-168 czcD P COG1230 Co Zn Cd efflux system component
PBLMHBDN_00525 4e-195 trkA P Oxidoreductase
PBLMHBDN_00528 1.8e-14 ykkA S Protein of unknown function (DUF664)
PBLMHBDN_00529 3.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
PBLMHBDN_00531 6.9e-195 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
PBLMHBDN_00532 2.6e-51 ydeH
PBLMHBDN_00533 6.8e-165 S Sodium Bile acid symporter family
PBLMHBDN_00534 3.8e-201 adhA 1.1.1.1 C alcohol dehydrogenase
PBLMHBDN_00535 1.8e-66 yraB K helix_turn_helix, mercury resistance
PBLMHBDN_00536 2.3e-224 mleN_2 C antiporter
PBLMHBDN_00537 5.4e-256 K helix_turn_helix gluconate operon transcriptional repressor
PBLMHBDN_00538 6e-114 paiB K Transcriptional regulator
PBLMHBDN_00540 1.1e-177 ydeR EGP Major facilitator Superfamily
PBLMHBDN_00541 1.2e-100 ydeS K Transcriptional regulator
PBLMHBDN_00542 1.4e-47 yraD M Spore coat protein
PBLMHBDN_00543 5.4e-24 yraE
PBLMHBDN_00544 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PBLMHBDN_00545 8.4e-63 yraF M Spore coat protein
PBLMHBDN_00546 1.3e-35 yraG
PBLMHBDN_00547 3.9e-216 ydfH 2.7.13.3 T Histidine kinase
PBLMHBDN_00548 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PBLMHBDN_00549 0.0 ydfJ S drug exporters of the RND superfamily
PBLMHBDN_00550 6.7e-133 puuD S Peptidase C26
PBLMHBDN_00551 6.7e-298 expZ S ABC transporter
PBLMHBDN_00552 5.7e-97 ynaD J Acetyltransferase (GNAT) domain
PBLMHBDN_00553 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
PBLMHBDN_00554 3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
PBLMHBDN_00555 1.8e-210 tcaB EGP Major facilitator Superfamily
PBLMHBDN_00556 1.1e-223 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PBLMHBDN_00557 5e-156 K Helix-turn-helix XRE-family like proteins
PBLMHBDN_00558 3.6e-121 ydhB S membrane transporter protein
PBLMHBDN_00559 2.2e-81 bltD 2.3.1.57 K FR47-like protein
PBLMHBDN_00560 2.2e-148 bltR K helix_turn_helix, mercury resistance
PBLMHBDN_00561 1.8e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PBLMHBDN_00562 7.3e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
PBLMHBDN_00563 7e-144 ycgJ_1 Q ubiE/COQ5 methyltransferase family
PBLMHBDN_00564 1.4e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
PBLMHBDN_00565 6.9e-119 ydhC K FCD
PBLMHBDN_00566 9.2e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PBLMHBDN_00569 1.4e-261 pbpE V Beta-lactamase
PBLMHBDN_00571 5.5e-98 ydhK M Protein of unknown function (DUF1541)
PBLMHBDN_00572 2e-195 pbuE EGP Major facilitator Superfamily
PBLMHBDN_00573 1.5e-132 ydhQ K UTRA
PBLMHBDN_00574 9.9e-118 K FCD
PBLMHBDN_00575 8.2e-216 yeaN P COG2807 Cyanate permease
PBLMHBDN_00576 2.6e-49 sugE P Small Multidrug Resistance protein
PBLMHBDN_00577 2.3e-51 ykkC P Small Multidrug Resistance protein
PBLMHBDN_00578 8.5e-102 yvdT K Transcriptional regulator
PBLMHBDN_00579 2.1e-296 yveA E amino acid
PBLMHBDN_00580 3.3e-163 ydhU P Catalase
PBLMHBDN_00581 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
PBLMHBDN_00582 7.5e-183 yhfP 1.1.1.1 C Quinone oxidoreductase
PBLMHBDN_00583 2.4e-251 iolT EGP Major facilitator Superfamily
PBLMHBDN_00586 3.4e-39 S COG NOG14552 non supervised orthologous group
PBLMHBDN_00587 7.8e-08
PBLMHBDN_00589 1.3e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PBLMHBDN_00590 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
PBLMHBDN_00591 2.5e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
PBLMHBDN_00592 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PBLMHBDN_00593 2.8e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PBLMHBDN_00594 0.0 ydiF S ABC transporter
PBLMHBDN_00595 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PBLMHBDN_00596 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PBLMHBDN_00597 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PBLMHBDN_00598 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PBLMHBDN_00599 1.7e-27 ydiK S Domain of unknown function (DUF4305)
PBLMHBDN_00600 9.6e-127 ydiL S CAAX protease self-immunity
PBLMHBDN_00601 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PBLMHBDN_00602 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PBLMHBDN_00603 1.5e-24 S Protein of unknown function (DUF4064)
PBLMHBDN_00604 0.0 K NB-ARC domain
PBLMHBDN_00605 5e-201 gutB 1.1.1.14 E Dehydrogenase
PBLMHBDN_00606 1.6e-30 gutA G MFS/sugar transport protein
PBLMHBDN_00607 4.7e-205 gutA G MFS/sugar transport protein
PBLMHBDN_00608 1.4e-170 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
PBLMHBDN_00609 4.7e-30 yjdJ S Domain of unknown function (DUF4306)
PBLMHBDN_00610 3.3e-113 pspA KT Phage shock protein A
PBLMHBDN_00611 6.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PBLMHBDN_00612 1.3e-115 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
PBLMHBDN_00613 1.8e-144 ydjI S virion core protein (lumpy skin disease virus)
PBLMHBDN_00614 0.0 yrhL I Acyltransferase family
PBLMHBDN_00615 1.4e-145 rsiV S Protein of unknown function (DUF3298)
PBLMHBDN_00616 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
PBLMHBDN_00617 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
PBLMHBDN_00618 1.2e-61 ydjM M Lytic transglycolase
PBLMHBDN_00619 2e-133 ydjN U Involved in the tonB-independent uptake of proteins
PBLMHBDN_00621 7.2e-35 ydjO S Cold-inducible protein YdjO
PBLMHBDN_00622 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
PBLMHBDN_00623 4.8e-244 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
PBLMHBDN_00624 3e-176 yeaC S COG0714 MoxR-like ATPases
PBLMHBDN_00625 2.5e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PBLMHBDN_00626 0.0 yebA E COG1305 Transglutaminase-like enzymes
PBLMHBDN_00627 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PBLMHBDN_00628 5e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
PBLMHBDN_00629 1.4e-246 S Domain of unknown function (DUF4179)
PBLMHBDN_00630 8.1e-209 pbuG S permease
PBLMHBDN_00631 1.5e-125 yebC M Membrane
PBLMHBDN_00633 7.5e-92 yebE S UPF0316 protein
PBLMHBDN_00634 5.5e-29 yebG S NETI protein
PBLMHBDN_00635 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PBLMHBDN_00636 3.6e-224 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PBLMHBDN_00637 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PBLMHBDN_00638 3.8e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PBLMHBDN_00639 8.4e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PBLMHBDN_00640 4.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PBLMHBDN_00641 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PBLMHBDN_00642 1.2e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PBLMHBDN_00643 1.9e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PBLMHBDN_00644 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PBLMHBDN_00645 6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PBLMHBDN_00646 4.5e-233 purD 6.3.4.13 F Belongs to the GARS family
PBLMHBDN_00647 2.6e-25 S Protein of unknown function (DUF2892)
PBLMHBDN_00648 0.0 yerA 3.5.4.2 F adenine deaminase
PBLMHBDN_00649 1.5e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
PBLMHBDN_00650 2.4e-50 yerC S protein conserved in bacteria
PBLMHBDN_00651 4.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
PBLMHBDN_00652 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PBLMHBDN_00653 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PBLMHBDN_00654 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBLMHBDN_00655 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
PBLMHBDN_00656 1.8e-192 yerI S homoserine kinase type II (protein kinase fold)
PBLMHBDN_00657 1.3e-120 sapB S MgtC SapB transporter
PBLMHBDN_00658 1.4e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBLMHBDN_00659 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PBLMHBDN_00660 3e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PBLMHBDN_00661 3.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PBLMHBDN_00662 2.6e-152 yerO K Transcriptional regulator
PBLMHBDN_00663 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PBLMHBDN_00664 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PBLMHBDN_00665 1.9e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PBLMHBDN_00666 8e-79 KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PBLMHBDN_00668 9e-33 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PBLMHBDN_00669 4.5e-63 fabZ 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PBLMHBDN_00670 9.6e-195 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PBLMHBDN_00671 8.3e-131 2.3.1.179 I 3-oxoacyl-[acyl-carrier-protein] synthase activity
PBLMHBDN_00672 6.5e-112 IQ reductase
PBLMHBDN_00673 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
PBLMHBDN_00674 6.5e-138 cylB V ABC-2 type transporter
PBLMHBDN_00675 5.9e-61 S Protein of unknown function, DUF600
PBLMHBDN_00676 3.8e-52 S Protein of unknown function, DUF600
PBLMHBDN_00677 9.4e-127 yeeN K transcriptional regulatory protein
PBLMHBDN_00679 6.9e-108 aadK G Streptomycin adenylyltransferase
PBLMHBDN_00680 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
PBLMHBDN_00681 3.3e-45 cotJB S CotJB protein
PBLMHBDN_00682 8.9e-104 cotJC P Spore Coat
PBLMHBDN_00683 5e-93 yesJ K Acetyltransferase (GNAT) family
PBLMHBDN_00685 7.4e-121 yetF S membrane
PBLMHBDN_00686 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
PBLMHBDN_00687 3.4e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PBLMHBDN_00688 3.2e-153 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PBLMHBDN_00689 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
PBLMHBDN_00690 5.3e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
PBLMHBDN_00691 6.9e-105 yetJ S Belongs to the BI1 family
PBLMHBDN_00692 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
PBLMHBDN_00693 5.4e-206 yetM CH FAD binding domain
PBLMHBDN_00694 2.6e-197 yetN S Protein of unknown function (DUF3900)
PBLMHBDN_00695 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
PBLMHBDN_00697 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
PBLMHBDN_00698 1.5e-161 V ATPases associated with a variety of cellular activities
PBLMHBDN_00699 2.8e-126 V ABC-2 type transporter
PBLMHBDN_00700 1.4e-69 S protein homooligomerization
PBLMHBDN_00701 6.6e-125
PBLMHBDN_00702 9.8e-183 S ATP diphosphatase activity
PBLMHBDN_00703 1.1e-261 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
PBLMHBDN_00704 8.6e-153 sagB C Nitroreductase family
PBLMHBDN_00705 2.8e-112 S CAAX protease self-immunity
PBLMHBDN_00706 1.5e-144 2.1.1.163, 2.1.1.201 Q methyltransferase
PBLMHBDN_00707 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PBLMHBDN_00708 1.8e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
PBLMHBDN_00709 7.1e-172 yfnG 4.2.1.45 M dehydratase
PBLMHBDN_00710 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
PBLMHBDN_00711 8.9e-220 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
PBLMHBDN_00712 6.9e-186 yfnD M Nucleotide-diphospho-sugar transferase
PBLMHBDN_00713 4.9e-216 fsr P COG0477 Permeases of the major facilitator superfamily
PBLMHBDN_00714 3e-246 yfnA E amino acid
PBLMHBDN_00715 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PBLMHBDN_00716 7.5e-107 yfmS NT chemotaxis protein
PBLMHBDN_00717 5.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
PBLMHBDN_00718 5.5e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PBLMHBDN_00719 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PBLMHBDN_00720 1.8e-69 yfmP K transcriptional
PBLMHBDN_00721 7.5e-206 yfmO EGP Major facilitator Superfamily
PBLMHBDN_00722 3.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PBLMHBDN_00723 5.7e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
PBLMHBDN_00724 2.8e-44 yfmK 2.3.1.128 K acetyltransferase
PBLMHBDN_00725 7.9e-188 yfmJ S N-terminal domain of oxidoreductase
PBLMHBDN_00726 2.7e-24 S Protein of unknown function (DUF3212)
PBLMHBDN_00727 1.3e-57 yflT S Heat induced stress protein YflT
PBLMHBDN_00728 1e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
PBLMHBDN_00729 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
PBLMHBDN_00730 5.2e-27 Q PFAM Collagen triple helix
PBLMHBDN_00731 1.3e-74 M1-820 Q Collagen triple helix repeat (20 copies)
PBLMHBDN_00732 3.3e-273 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PBLMHBDN_00733 2.6e-118 citT T response regulator
PBLMHBDN_00734 4.6e-177 yflP S Tripartite tricarboxylate transporter family receptor
PBLMHBDN_00735 3.6e-225 citM C Citrate transporter
PBLMHBDN_00736 4.8e-148 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
PBLMHBDN_00737 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PBLMHBDN_00738 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PBLMHBDN_00739 1.3e-122 yflK S protein conserved in bacteria
PBLMHBDN_00740 1.5e-14 yflJ S Protein of unknown function (DUF2639)
PBLMHBDN_00741 7e-19 yflI
PBLMHBDN_00742 3.1e-50 yflH S Protein of unknown function (DUF3243)
PBLMHBDN_00743 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
PBLMHBDN_00744 1.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
PBLMHBDN_00745 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
PBLMHBDN_00746 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PBLMHBDN_00747 8.6e-63 yhdN S Domain of unknown function (DUF1992)
PBLMHBDN_00748 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
PBLMHBDN_00749 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
PBLMHBDN_00750 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
PBLMHBDN_00751 2.8e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PBLMHBDN_00752 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PBLMHBDN_00753 1.3e-128 treR K transcriptional
PBLMHBDN_00754 4.5e-123 yfkO C nitroreductase
PBLMHBDN_00755 1e-123 yibF S YibE/F-like protein
PBLMHBDN_00756 1.1e-198 yibE S YibE/F-like protein
PBLMHBDN_00757 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
PBLMHBDN_00758 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
PBLMHBDN_00759 9.8e-186 K helix_turn _helix lactose operon repressor
PBLMHBDN_00760 1.2e-163 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PBLMHBDN_00761 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PBLMHBDN_00762 8.1e-192 ydiM EGP Major facilitator Superfamily
PBLMHBDN_00763 2.7e-29 yfkK S Belongs to the UPF0435 family
PBLMHBDN_00764 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PBLMHBDN_00765 1.7e-51 yfkI S gas vesicle protein
PBLMHBDN_00766 7.6e-144 yihY S Belongs to the UPF0761 family
PBLMHBDN_00767 2.5e-07
PBLMHBDN_00768 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
PBLMHBDN_00769 2.2e-185 cax P COG0387 Ca2 H antiporter
PBLMHBDN_00770 1.6e-143 yfkD S YfkD-like protein
PBLMHBDN_00771 6.8e-145 yfkC M Mechanosensitive ion channel
PBLMHBDN_00772 7.3e-219 yfkA S YfkB-like domain
PBLMHBDN_00773 4.9e-27 yfjT
PBLMHBDN_00774 9e-155 pdaA G deacetylase
PBLMHBDN_00775 5e-151 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PBLMHBDN_00776 3.9e-31
PBLMHBDN_00777 8.5e-184 corA P Mediates influx of magnesium ions
PBLMHBDN_00778 8.3e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PBLMHBDN_00779 8.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PBLMHBDN_00780 2.5e-43 S YfzA-like protein
PBLMHBDN_00781 3.5e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PBLMHBDN_00782 3.7e-87 yfjM S Psort location Cytoplasmic, score
PBLMHBDN_00783 6.4e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PBLMHBDN_00784 8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PBLMHBDN_00785 1.1e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PBLMHBDN_00786 2.3e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PBLMHBDN_00787 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
PBLMHBDN_00788 4.2e-15 sspH S Belongs to the SspH family
PBLMHBDN_00789 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PBLMHBDN_00790 5.1e-139 glvR F Helix-turn-helix domain, rpiR family
PBLMHBDN_00791 8.3e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PBLMHBDN_00792 6.2e-310 yfiB3 V ABC transporter
PBLMHBDN_00793 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
PBLMHBDN_00794 9.2e-63 mhqP S DoxX
PBLMHBDN_00795 5e-159 yfiE 1.13.11.2 S glyoxalase
PBLMHBDN_00796 3.3e-164 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PBLMHBDN_00797 1.1e-95 padR K transcriptional
PBLMHBDN_00798 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
PBLMHBDN_00799 2.7e-178 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PBLMHBDN_00800 2e-19 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PBLMHBDN_00801 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
PBLMHBDN_00802 4.5e-45 yrdF K ribonuclease inhibitor
PBLMHBDN_00803 7.6e-97 yfiT S Belongs to the metal hydrolase YfiT family
PBLMHBDN_00804 4.3e-289 yfiU EGP Major facilitator Superfamily
PBLMHBDN_00805 6.2e-82 yfiV K transcriptional
PBLMHBDN_00806 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PBLMHBDN_00807 8.5e-162 yfhB 5.3.3.17 S PhzF family
PBLMHBDN_00808 1.7e-105 yfhC C nitroreductase
PBLMHBDN_00809 2.1e-25 yfhD S YfhD-like protein
PBLMHBDN_00811 7.5e-166 yfhF S nucleoside-diphosphate sugar epimerase
PBLMHBDN_00812 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
PBLMHBDN_00813 2.5e-52 yfhH S Protein of unknown function (DUF1811)
PBLMHBDN_00814 1.1e-204 yfhI EGP Major facilitator Superfamily
PBLMHBDN_00816 5.3e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
PBLMHBDN_00817 2.2e-44 yfhJ S WVELL protein
PBLMHBDN_00818 1.7e-93 batE T Bacterial SH3 domain homologues
PBLMHBDN_00819 2e-31 yfhL S SdpI/YhfL protein family
PBLMHBDN_00820 8.2e-170 yfhM S Alpha/beta hydrolase family
PBLMHBDN_00821 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PBLMHBDN_00822 0.0 yfhO S Bacterial membrane protein YfhO
PBLMHBDN_00823 8.8e-185 yfhP S membrane-bound metal-dependent
PBLMHBDN_00824 4.8e-207 mutY L A G-specific
PBLMHBDN_00825 3.1e-36 yfhS
PBLMHBDN_00826 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PBLMHBDN_00828 1.5e-37 ygaB S YgaB-like protein
PBLMHBDN_00829 2.2e-104 ygaC J Belongs to the UPF0374 family
PBLMHBDN_00830 3.5e-300 ygaD V ABC transporter
PBLMHBDN_00831 2.7e-178 ygaE S Membrane
PBLMHBDN_00832 1.8e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
PBLMHBDN_00833 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
PBLMHBDN_00834 1.8e-80 perR P Belongs to the Fur family
PBLMHBDN_00835 3.3e-56 ygzB S UPF0295 protein
PBLMHBDN_00836 1.1e-164 ygxA S Nucleotidyltransferase-like
PBLMHBDN_00837 3.4e-39 S COG NOG14552 non supervised orthologous group
PBLMHBDN_00842 7.8e-08
PBLMHBDN_00850 1.6e-08
PBLMHBDN_00854 9e-21 C Na+/H+ antiporter family
PBLMHBDN_00855 4.4e-129 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
PBLMHBDN_00856 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PBLMHBDN_00857 9e-264 ygaK C Berberine and berberine like
PBLMHBDN_00859 3.7e-230 oppA5 E PFAM extracellular solute-binding protein family 5
PBLMHBDN_00860 9.8e-148 appB P Binding-protein-dependent transport system inner membrane component
PBLMHBDN_00861 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBLMHBDN_00862 3.7e-134 oppD3 P Belongs to the ABC transporter superfamily
PBLMHBDN_00863 3.1e-133 oppF3 E Belongs to the ABC transporter superfamily
PBLMHBDN_00864 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PBLMHBDN_00865 5.1e-181 S Amidohydrolase
PBLMHBDN_00866 1.8e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PBLMHBDN_00867 3.2e-178 ssuA M Sulfonate ABC transporter
PBLMHBDN_00868 2.9e-143 ssuC P ABC transporter (permease)
PBLMHBDN_00869 8.5e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
PBLMHBDN_00870 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PBLMHBDN_00871 3.3e-80 ygaO
PBLMHBDN_00872 4.8e-23 K Transcriptional regulator
PBLMHBDN_00874 7.2e-107 yhzB S B3/4 domain
PBLMHBDN_00875 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PBLMHBDN_00876 1.4e-173 yhbB S Putative amidase domain
PBLMHBDN_00877 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PBLMHBDN_00878 3e-108 yhbD K Protein of unknown function (DUF4004)
PBLMHBDN_00879 5.2e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
PBLMHBDN_00880 1e-61 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
PBLMHBDN_00882 0.0 prkA T Ser protein kinase
PBLMHBDN_00883 3.9e-215 yhbH S Belongs to the UPF0229 family
PBLMHBDN_00884 4.6e-74 yhbI K DNA-binding transcription factor activity
PBLMHBDN_00885 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
PBLMHBDN_00886 8.4e-285 yhcA EGP Major facilitator Superfamily
PBLMHBDN_00887 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
PBLMHBDN_00888 3.8e-55 yhcC
PBLMHBDN_00889 2.1e-52
PBLMHBDN_00890 2.8e-61 yhcF K Transcriptional regulator
PBLMHBDN_00891 4.8e-123 yhcG V ABC transporter, ATP-binding protein
PBLMHBDN_00892 1.2e-166 yhcH V ABC transporter, ATP-binding protein
PBLMHBDN_00893 8.2e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PBLMHBDN_00894 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
PBLMHBDN_00895 5.7e-144 metQ M Belongs to the nlpA lipoprotein family
PBLMHBDN_00896 6.7e-185 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
PBLMHBDN_00897 4.3e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PBLMHBDN_00898 2.5e-53 yhcM
PBLMHBDN_00899 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PBLMHBDN_00900 2.2e-160 yhcP
PBLMHBDN_00901 8.4e-114 yhcQ M Spore coat protein
PBLMHBDN_00902 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
PBLMHBDN_00903 1.7e-105 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
PBLMHBDN_00904 9e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PBLMHBDN_00905 1.3e-69 yhcU S Family of unknown function (DUF5365)
PBLMHBDN_00906 9.9e-68 yhcV S COG0517 FOG CBS domain
PBLMHBDN_00907 1.9e-124 yhcW 5.4.2.6 S hydrolase
PBLMHBDN_00908 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PBLMHBDN_00909 2.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PBLMHBDN_00910 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PBLMHBDN_00911 7.7e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
PBLMHBDN_00912 1.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PBLMHBDN_00913 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PBLMHBDN_00914 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PBLMHBDN_00915 8.5e-70 yhcY 2.7.13.3 T Histidine kinase
PBLMHBDN_00916 4.3e-37 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PBLMHBDN_00917 3.3e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
PBLMHBDN_00918 2.5e-39 yhdB S YhdB-like protein
PBLMHBDN_00919 1.1e-53 yhdC S Protein of unknown function (DUF3889)
PBLMHBDN_00920 3.7e-215 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PBLMHBDN_00921 1.6e-73 nsrR K Transcriptional regulator
PBLMHBDN_00922 2.6e-243 ygxB M Conserved TM helix
PBLMHBDN_00923 1.8e-270 ycgB S Stage V sporulation protein R
PBLMHBDN_00924 1.7e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
PBLMHBDN_00925 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PBLMHBDN_00926 1.3e-162 citR K Transcriptional regulator
PBLMHBDN_00927 1.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
PBLMHBDN_00928 2.5e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PBLMHBDN_00929 1.2e-250 yhdG E amino acid
PBLMHBDN_00930 2.9e-198 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PBLMHBDN_00931 8.1e-45 yhdK S Sigma-M inhibitor protein
PBLMHBDN_00932 1.3e-201 yhdL S Sigma factor regulator N-terminal
PBLMHBDN_00933 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
PBLMHBDN_00934 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PBLMHBDN_00935 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PBLMHBDN_00936 2.8e-70 cueR K transcriptional
PBLMHBDN_00937 1.9e-225 yhdR 2.6.1.1 E Aminotransferase
PBLMHBDN_00938 9.5e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PBLMHBDN_00939 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
PBLMHBDN_00940 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PBLMHBDN_00941 4.4e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PBLMHBDN_00942 1.8e-125 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PBLMHBDN_00944 3.5e-205 yhdY M Mechanosensitive ion channel
PBLMHBDN_00945 2.9e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PBLMHBDN_00946 1.1e-155 yheN G deacetylase
PBLMHBDN_00947 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PBLMHBDN_00948 3e-87 pksA K Transcriptional regulator
PBLMHBDN_00949 1.8e-93 ymcC S Membrane
PBLMHBDN_00950 1.1e-84 T universal stress protein
PBLMHBDN_00952 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
PBLMHBDN_00953 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
PBLMHBDN_00954 1.8e-110 yheG GM NAD(P)H-binding
PBLMHBDN_00956 1.3e-28 sspB S spore protein
PBLMHBDN_00957 1.7e-36 yheE S Family of unknown function (DUF5342)
PBLMHBDN_00958 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
PBLMHBDN_00959 3.4e-213 yheC HJ YheC/D like ATP-grasp
PBLMHBDN_00960 3.6e-205 yheB S Belongs to the UPF0754 family
PBLMHBDN_00961 4.4e-53 yheA S Belongs to the UPF0342 family
PBLMHBDN_00962 1.4e-201 yhaZ L DNA alkylation repair enzyme
PBLMHBDN_00963 4.7e-157 yhaX S haloacid dehalogenase-like hydrolase
PBLMHBDN_00964 2.7e-293 hemZ H coproporphyrinogen III oxidase
PBLMHBDN_00965 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
PBLMHBDN_00966 3.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
PBLMHBDN_00967 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
PBLMHBDN_00969 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
PBLMHBDN_00970 2.8e-14 S YhzD-like protein
PBLMHBDN_00971 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
PBLMHBDN_00972 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
PBLMHBDN_00973 1e-234 yhaO L DNA repair exonuclease
PBLMHBDN_00974 0.0 yhaN L AAA domain
PBLMHBDN_00975 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
PBLMHBDN_00976 1.8e-31 yhaL S Sporulation protein YhaL
PBLMHBDN_00977 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PBLMHBDN_00978 7e-95 yhaK S Putative zincin peptidase
PBLMHBDN_00979 9.9e-55 yhaI S Protein of unknown function (DUF1878)
PBLMHBDN_00980 8.6e-113 hpr K Negative regulator of protease production and sporulation
PBLMHBDN_00981 6.2e-39 yhaH S YtxH-like protein
PBLMHBDN_00982 2e-17
PBLMHBDN_00983 1.4e-76 trpP S Tryptophan transporter TrpP
PBLMHBDN_00984 6e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PBLMHBDN_00985 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PBLMHBDN_00986 3.3e-135 ecsA V transporter (ATP-binding protein)
PBLMHBDN_00987 1.9e-220 ecsB U ABC transporter
PBLMHBDN_00988 7.5e-121 ecsC S EcsC protein family
PBLMHBDN_00989 2e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PBLMHBDN_00990 6.2e-244 yhfA C membrane
PBLMHBDN_00991 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PBLMHBDN_00992 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PBLMHBDN_00993 9.5e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PBLMHBDN_00994 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PBLMHBDN_00995 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PBLMHBDN_00996 3.2e-101 yhgD K Transcriptional regulator
PBLMHBDN_00997 7.2e-245 yhgE S YhgE Pip N-terminal domain protein
PBLMHBDN_00998 9.6e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBLMHBDN_01000 6.6e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
PBLMHBDN_01001 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PBLMHBDN_01002 7.9e-11 yhfH S YhfH-like protein
PBLMHBDN_01003 2.2e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
PBLMHBDN_01004 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
PBLMHBDN_01005 7.9e-109 yhfK GM NmrA-like family
PBLMHBDN_01006 4.1e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
PBLMHBDN_01007 1.3e-64 yhfM
PBLMHBDN_01008 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
PBLMHBDN_01009 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
PBLMHBDN_01010 5.7e-150 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PBLMHBDN_01011 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
PBLMHBDN_01012 4.8e-199 vraB 2.3.1.9 I Belongs to the thiolase family
PBLMHBDN_01013 1.8e-278 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
PBLMHBDN_01014 3.5e-89 bioY S BioY family
PBLMHBDN_01015 6.9e-197 hemAT NT chemotaxis protein
PBLMHBDN_01016 3.5e-296 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
PBLMHBDN_01017 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PBLMHBDN_01018 5.4e-31 yhzC S IDEAL
PBLMHBDN_01019 1.9e-109 comK K Competence transcription factor
PBLMHBDN_01020 2.7e-51 frataxin S Domain of unknown function (DU1801)
PBLMHBDN_01021 4.2e-62 frataxin S Domain of unknown function (DU1801)
PBLMHBDN_01022 8.7e-125 yrpD S Domain of unknown function, YrpD
PBLMHBDN_01023 1.6e-42 yhjA S Excalibur calcium-binding domain
PBLMHBDN_01024 5.6e-47 S Belongs to the UPF0145 family
PBLMHBDN_01025 5e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBLMHBDN_01026 3.1e-27 yhjC S Protein of unknown function (DUF3311)
PBLMHBDN_01027 1.7e-60 yhjD
PBLMHBDN_01028 2.6e-109 yhjE S SNARE associated Golgi protein
PBLMHBDN_01029 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
PBLMHBDN_01030 7.5e-270 yhjG CH FAD binding domain
PBLMHBDN_01031 4.2e-92 yhjH K helix_turn_helix multiple antibiotic resistance protein
PBLMHBDN_01032 2.4e-188 abrB S membrane
PBLMHBDN_01033 3e-202 blt EGP Major facilitator Superfamily
PBLMHBDN_01034 1.1e-107 K QacR-like protein, C-terminal region
PBLMHBDN_01035 2.2e-93 yhjR S Rubrerythrin
PBLMHBDN_01036 2.5e-119 ydfS S Protein of unknown function (DUF421)
PBLMHBDN_01037 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
PBLMHBDN_01038 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PBLMHBDN_01039 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PBLMHBDN_01040 0.0 sbcC L COG0419 ATPase involved in DNA repair
PBLMHBDN_01041 1.3e-50 yisB V COG1403 Restriction endonuclease
PBLMHBDN_01042 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
PBLMHBDN_01043 1.1e-63 gerPE S Spore germination protein GerPE
PBLMHBDN_01044 3.1e-23 gerPD S Spore germination protein
PBLMHBDN_01045 1.4e-62 gerPC S Spore germination protein
PBLMHBDN_01046 1.8e-34 gerPB S cell differentiation
PBLMHBDN_01047 8.4e-34 gerPA S Spore germination protein
PBLMHBDN_01048 4.8e-07 yisI S Spo0E like sporulation regulatory protein
PBLMHBDN_01049 1.3e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PBLMHBDN_01050 3.2e-59 yisL S UPF0344 protein
PBLMHBDN_01051 1e-96 yisN S Protein of unknown function (DUF2777)
PBLMHBDN_01052 0.0 asnO 6.3.5.4 E Asparagine synthase
PBLMHBDN_01053 2.9e-131 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
PBLMHBDN_01054 1.5e-245 yisQ V Mate efflux family protein
PBLMHBDN_01055 5e-159 yisR K Transcriptional regulator
PBLMHBDN_01056 7.1e-144 purR K helix_turn _helix lactose operon repressor
PBLMHBDN_01057 5.8e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
PBLMHBDN_01058 4.4e-83 yisT S DinB family
PBLMHBDN_01059 1.6e-69 mcbG S Pentapeptide repeats (9 copies)
PBLMHBDN_01060 3.4e-79 yjcF S Acetyltransferase (GNAT) domain
PBLMHBDN_01061 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PBLMHBDN_01062 6.6e-55 yajQ S Belongs to the UPF0234 family
PBLMHBDN_01063 7.6e-160 cvfB S protein conserved in bacteria
PBLMHBDN_01064 1.1e-170 yufN S ABC transporter substrate-binding protein PnrA-like
PBLMHBDN_01065 6.5e-232 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PBLMHBDN_01067 3e-156 yitS S protein conserved in bacteria
PBLMHBDN_01068 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
PBLMHBDN_01069 2.7e-79 ipi S Intracellular proteinase inhibitor
PBLMHBDN_01070 4.4e-26 S Protein of unknown function (DUF3813)
PBLMHBDN_01071 3.5e-07
PBLMHBDN_01072 9.5e-152 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PBLMHBDN_01073 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
PBLMHBDN_01074 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
PBLMHBDN_01075 1.7e-72 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
PBLMHBDN_01076 1.5e-272 yitY C D-arabinono-1,4-lactone oxidase
PBLMHBDN_01077 1.2e-89 norB G Major Facilitator Superfamily
PBLMHBDN_01078 6.6e-198 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PBLMHBDN_01079 1.1e-225 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PBLMHBDN_01080 1.1e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
PBLMHBDN_01081 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PBLMHBDN_01082 1.3e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PBLMHBDN_01083 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
PBLMHBDN_01084 1.3e-174 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PBLMHBDN_01085 1.2e-27 yjzC S YjzC-like protein
PBLMHBDN_01086 3.3e-23 yjzD S Protein of unknown function (DUF2929)
PBLMHBDN_01087 8.4e-139 yjaU I carboxylic ester hydrolase activity
PBLMHBDN_01088 3.7e-102 yjaV
PBLMHBDN_01089 2.7e-165 med S Transcriptional activator protein med
PBLMHBDN_01090 1.1e-26 comZ S ComZ
PBLMHBDN_01091 1e-31 yjzB
PBLMHBDN_01092 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBLMHBDN_01093 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PBLMHBDN_01094 5.6e-149 yjaZ O Zn-dependent protease
PBLMHBDN_01095 4.8e-182 appD P Belongs to the ABC transporter superfamily
PBLMHBDN_01096 5e-187 appF E Belongs to the ABC transporter superfamily
PBLMHBDN_01097 4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
PBLMHBDN_01098 1.2e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBLMHBDN_01099 1e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBLMHBDN_01100 1.2e-145 yjbA S Belongs to the UPF0736 family
PBLMHBDN_01101 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PBLMHBDN_01102 0.0 oppA E ABC transporter substrate-binding protein
PBLMHBDN_01103 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBLMHBDN_01104 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBLMHBDN_01105 2.7e-202 oppD P Belongs to the ABC transporter superfamily
PBLMHBDN_01106 2.3e-170 oppF E Belongs to the ABC transporter superfamily
PBLMHBDN_01107 9.8e-230 S Putative glycosyl hydrolase domain
PBLMHBDN_01108 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PBLMHBDN_01109 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PBLMHBDN_01110 4.7e-109 yjbE P Integral membrane protein TerC family
PBLMHBDN_01111 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PBLMHBDN_01112 9.3e-217 yjbF S Competence protein
PBLMHBDN_01113 0.0 pepF E oligoendopeptidase F
PBLMHBDN_01114 5.8e-19
PBLMHBDN_01115 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PBLMHBDN_01116 4.8e-72 yjbI S Bacterial-like globin
PBLMHBDN_01117 1.2e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PBLMHBDN_01118 3.1e-96 yjbK S protein conserved in bacteria
PBLMHBDN_01119 8.6e-60 yjbL S Belongs to the UPF0738 family
PBLMHBDN_01120 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
PBLMHBDN_01121 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PBLMHBDN_01122 3.7e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PBLMHBDN_01123 4.4e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PBLMHBDN_01124 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PBLMHBDN_01125 9.9e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PBLMHBDN_01126 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
PBLMHBDN_01127 9.5e-211 thiO 1.4.3.19 E Glycine oxidase
PBLMHBDN_01128 6.7e-30 thiS H Thiamine biosynthesis
PBLMHBDN_01129 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PBLMHBDN_01130 3.3e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PBLMHBDN_01131 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PBLMHBDN_01132 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PBLMHBDN_01133 1.2e-87 yjbX S Spore coat protein
PBLMHBDN_01134 6.7e-83 cotZ S Spore coat protein
PBLMHBDN_01135 4.6e-93 cotY S Spore coat protein Z
PBLMHBDN_01136 5.1e-71 cotX S Spore Coat Protein X and V domain
PBLMHBDN_01137 6.8e-21 cotW
PBLMHBDN_01138 1.4e-52 cotV S Spore Coat Protein X and V domain
PBLMHBDN_01139 5.6e-56 yjcA S Protein of unknown function (DUF1360)
PBLMHBDN_01143 3.8e-38 spoVIF S Stage VI sporulation protein F
PBLMHBDN_01144 0.0 yjcD 3.6.4.12 L DNA helicase
PBLMHBDN_01145 1.3e-35
PBLMHBDN_01146 7e-141 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
PBLMHBDN_01147 5.7e-124 S ABC-2 type transporter
PBLMHBDN_01148 1.3e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
PBLMHBDN_01149 2.7e-35 K SpoVT / AbrB like domain
PBLMHBDN_01151 2.3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PBLMHBDN_01152 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
PBLMHBDN_01153 3.6e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
PBLMHBDN_01154 1.3e-210 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PBLMHBDN_01155 7.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PBLMHBDN_01157 2.8e-29
PBLMHBDN_01158 9.9e-83
PBLMHBDN_01159 3e-179 yobL S Bacterial EndoU nuclease
PBLMHBDN_01160 3.6e-94
PBLMHBDN_01162 2.8e-128
PBLMHBDN_01164 9e-12
PBLMHBDN_01167 8.5e-58 E Glyoxalase-like domain
PBLMHBDN_01168 3.9e-162 bla 3.5.2.6 V beta-lactamase
PBLMHBDN_01169 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
PBLMHBDN_01170 1.3e-249 yfjF EGP Belongs to the major facilitator superfamily
PBLMHBDN_01171 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
PBLMHBDN_01172 3.6e-218 ganA 3.2.1.89 G arabinogalactan
PBLMHBDN_01173 5.4e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PBLMHBDN_01174 5e-187 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PBLMHBDN_01175 1e-215 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PBLMHBDN_01176 1.7e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PBLMHBDN_01177 2.6e-49 lacF 2.7.1.207 G phosphotransferase system
PBLMHBDN_01178 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
PBLMHBDN_01179 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
PBLMHBDN_01180 5.1e-122 5.4.2.6 S Haloacid dehalogenase-like hydrolase
PBLMHBDN_01181 3.7e-144 N Kelch motif
PBLMHBDN_01183 8.1e-106 yhiD S MgtC SapB transporter
PBLMHBDN_01184 2.9e-21 yjfB S Putative motility protein
PBLMHBDN_01185 2.3e-66 T PhoQ Sensor
PBLMHBDN_01186 5.9e-100 yjgB S Domain of unknown function (DUF4309)
PBLMHBDN_01187 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
PBLMHBDN_01188 4.3e-92 yjgD S Protein of unknown function (DUF1641)
PBLMHBDN_01189 1.7e-224 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
PBLMHBDN_01190 3.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PBLMHBDN_01191 6.8e-29
PBLMHBDN_01192 8e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PBLMHBDN_01193 2.1e-124 ybbM S transport system, permease component
PBLMHBDN_01194 7.1e-130 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
PBLMHBDN_01195 3.9e-176 yjlA EG Putative multidrug resistance efflux transporter
PBLMHBDN_01196 1.2e-88 yjlB S Cupin domain
PBLMHBDN_01197 7e-66 yjlC S Protein of unknown function (DUF1641)
PBLMHBDN_01198 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
PBLMHBDN_01199 1.9e-272 uxaC 5.3.1.12 G glucuronate isomerase
PBLMHBDN_01200 3.3e-253 yjmB G symporter YjmB
PBLMHBDN_01201 7e-181 exuR K transcriptional
PBLMHBDN_01202 4e-278 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
PBLMHBDN_01203 1.1e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
PBLMHBDN_01204 4e-87 T Transcriptional regulatory protein, C terminal
PBLMHBDN_01205 1.4e-131 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PBLMHBDN_01206 2.1e-15 V ABC transporter, ATP-binding protein
PBLMHBDN_01208 1.9e-130 MA20_18170 S membrane transporter protein
PBLMHBDN_01209 3.4e-77 yjoA S DinB family
PBLMHBDN_01210 4.9e-215 S response regulator aspartate phosphatase
PBLMHBDN_01212 2e-161 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PBLMHBDN_01213 8e-61 yjqA S Bacterial PH domain
PBLMHBDN_01214 1.4e-110 yjqB S phage-related replication protein
PBLMHBDN_01216 2.9e-110 xkdA E IrrE N-terminal-like domain
PBLMHBDN_01217 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
PBLMHBDN_01219 6.4e-111 xkdB K sequence-specific DNA binding
PBLMHBDN_01220 6.5e-119 xkdC L Bacterial dnaA protein
PBLMHBDN_01223 2e-10 yqaO S Phage-like element PBSX protein XtrA
PBLMHBDN_01224 2.4e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PBLMHBDN_01225 1e-110 xtmA L phage terminase small subunit
PBLMHBDN_01226 2.7e-209 xtmB S phage terminase, large subunit
PBLMHBDN_01227 5.1e-241 yqbA S portal protein
PBLMHBDN_01228 1.7e-87 yqbD 2.1.1.72 L Putative phage serine protease XkdF
PBLMHBDN_01229 4.6e-158 xkdG S Phage capsid family
PBLMHBDN_01230 9.7e-46 yqbG S Protein of unknown function (DUF3199)
PBLMHBDN_01231 2.7e-42 yqbH S Domain of unknown function (DUF3599)
PBLMHBDN_01232 5.3e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
PBLMHBDN_01233 3.2e-56 xkdJ
PBLMHBDN_01234 8.2e-15
PBLMHBDN_01235 1.3e-225 xkdK S Phage tail sheath C-terminal domain
PBLMHBDN_01236 2e-74 xkdM S Phage tail tube protein
PBLMHBDN_01237 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
PBLMHBDN_01238 3.4e-19
PBLMHBDN_01239 2.8e-193 xkdO L Transglycosylase SLT domain
PBLMHBDN_01240 6.6e-111 xkdP S Lysin motif
PBLMHBDN_01241 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
PBLMHBDN_01242 7.2e-32 xkdR S Protein of unknown function (DUF2577)
PBLMHBDN_01243 1.4e-58 xkdS S Protein of unknown function (DUF2634)
PBLMHBDN_01244 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PBLMHBDN_01245 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
PBLMHBDN_01246 1.2e-26
PBLMHBDN_01247 1.7e-91
PBLMHBDN_01249 1.6e-28 xkdX
PBLMHBDN_01250 1.4e-136 xepA
PBLMHBDN_01251 8.7e-38 xhlA S Haemolysin XhlA
PBLMHBDN_01252 6.7e-38 xhlB S SPP1 phage holin
PBLMHBDN_01253 4.6e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PBLMHBDN_01254 8.7e-23 spoIISB S Stage II sporulation protein SB
PBLMHBDN_01255 1.7e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
PBLMHBDN_01256 5.8e-175 pit P phosphate transporter
PBLMHBDN_01257 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
PBLMHBDN_01258 1.1e-242 steT E amino acid
PBLMHBDN_01259 8.2e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
PBLMHBDN_01260 1.8e-303 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PBLMHBDN_01261 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PBLMHBDN_01262 1.3e-16 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PBLMHBDN_01263 1.9e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PBLMHBDN_01264 2.5e-278 yubD P Major Facilitator Superfamily
PBLMHBDN_01265 4.2e-155 dppA E D-aminopeptidase
PBLMHBDN_01266 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBLMHBDN_01267 1.1e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PBLMHBDN_01268 2.2e-190 dppD P Belongs to the ABC transporter superfamily
PBLMHBDN_01269 0.0 dppE E ABC transporter substrate-binding protein
PBLMHBDN_01270 9.9e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
PBLMHBDN_01271 2.4e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
PBLMHBDN_01272 3.9e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PBLMHBDN_01273 6.2e-182 ykfD E Belongs to the ABC transporter superfamily
PBLMHBDN_01274 1.6e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
PBLMHBDN_01275 1.5e-158 ykgA E Amidinotransferase
PBLMHBDN_01276 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
PBLMHBDN_01277 7.4e-100 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PBLMHBDN_01278 1.4e-51 ykkC P Multidrug resistance protein
PBLMHBDN_01279 2.5e-47 ykkD P Multidrug resistance protein
PBLMHBDN_01280 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
PBLMHBDN_01281 2.5e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PBLMHBDN_01282 1.7e-224 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PBLMHBDN_01283 4.1e-69 ohrA O Organic hydroperoxide resistance protein
PBLMHBDN_01284 1.9e-76 ohrR K COG1846 Transcriptional regulators
PBLMHBDN_01285 4.2e-71 ohrB O Organic hydroperoxide resistance protein
PBLMHBDN_01286 1e-54 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PBLMHBDN_01288 1.1e-214 M Glycosyl transferase family 2
PBLMHBDN_01289 1.9e-118 M PFAM Collagen triple helix repeat (20 copies)
PBLMHBDN_01290 1.2e-214 hcaT 1.5.1.2 EGP Major facilitator Superfamily
PBLMHBDN_01291 2.2e-120 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PBLMHBDN_01292 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PBLMHBDN_01293 1.5e-175 isp O Belongs to the peptidase S8 family
PBLMHBDN_01294 8.6e-148 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PBLMHBDN_01295 1e-131 ykoC P Cobalt transport protein
PBLMHBDN_01296 1.5e-300 P ABC transporter, ATP-binding protein
PBLMHBDN_01297 1e-97 ykoE S ABC-type cobalt transport system, permease component
PBLMHBDN_01298 7.4e-244 ydhD M Glycosyl hydrolase
PBLMHBDN_01300 3.2e-237 mgtE P Acts as a magnesium transporter
PBLMHBDN_01301 5.4e-53 tnrA K transcriptional
PBLMHBDN_01302 1.9e-16
PBLMHBDN_01303 3.1e-26 ykoL
PBLMHBDN_01304 1.1e-80 ykoM K transcriptional
PBLMHBDN_01305 2.2e-99 ykoP G polysaccharide deacetylase
PBLMHBDN_01306 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
PBLMHBDN_01307 6.1e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PBLMHBDN_01308 1.1e-98 ykoX S membrane-associated protein
PBLMHBDN_01309 4.3e-133 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PBLMHBDN_01310 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBLMHBDN_01311 9e-119 rsgI S Anti-sigma factor N-terminus
PBLMHBDN_01312 2.5e-26 sspD S small acid-soluble spore protein
PBLMHBDN_01313 2.3e-125 ykrK S Domain of unknown function (DUF1836)
PBLMHBDN_01314 4.1e-156 htpX O Belongs to the peptidase M48B family
PBLMHBDN_01315 6.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
PBLMHBDN_01316 2.8e-112 ydfR S Protein of unknown function (DUF421)
PBLMHBDN_01317 8.7e-23 ykzE
PBLMHBDN_01318 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
PBLMHBDN_01319 0.0 kinE 2.7.13.3 T Histidine kinase
PBLMHBDN_01320 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PBLMHBDN_01322 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PBLMHBDN_01323 3.6e-224 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PBLMHBDN_01324 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PBLMHBDN_01325 3.5e-227 mtnE 2.6.1.83 E Aminotransferase
PBLMHBDN_01326 3.9e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
PBLMHBDN_01327 3.9e-133 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PBLMHBDN_01328 2.3e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
PBLMHBDN_01329 7.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PBLMHBDN_01330 3.4e-10 S Spo0E like sporulation regulatory protein
PBLMHBDN_01331 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
PBLMHBDN_01332 5.5e-77 ykvE K transcriptional
PBLMHBDN_01333 2.7e-127 motB N Flagellar motor protein
PBLMHBDN_01334 3.3e-136 motA N flagellar motor
PBLMHBDN_01335 0.0 clpE O Belongs to the ClpA ClpB family
PBLMHBDN_01336 5.1e-182 ykvI S membrane
PBLMHBDN_01337 2.2e-183
PBLMHBDN_01338 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PBLMHBDN_01339 1.7e-78 queD 4.1.2.50, 4.2.3.12 H synthase
PBLMHBDN_01340 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PBLMHBDN_01341 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PBLMHBDN_01342 3.5e-45 ykvR S Protein of unknown function (DUF3219)
PBLMHBDN_01343 7.8e-25 ykvS S protein conserved in bacteria
PBLMHBDN_01344 3.9e-27
PBLMHBDN_01345 6.9e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
PBLMHBDN_01346 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PBLMHBDN_01347 1.7e-87 stoA CO thiol-disulfide
PBLMHBDN_01348 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PBLMHBDN_01349 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
PBLMHBDN_01351 7.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
PBLMHBDN_01352 8.7e-156 glcT K antiterminator
PBLMHBDN_01353 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PBLMHBDN_01354 2.1e-39 ptsH G phosphocarrier protein HPr
PBLMHBDN_01355 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PBLMHBDN_01356 6.1e-38 splA S Transcriptional regulator
PBLMHBDN_01357 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
PBLMHBDN_01358 1.9e-262 mcpC NT chemotaxis protein
PBLMHBDN_01359 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PBLMHBDN_01360 9.8e-114 ykwD J protein with SCP PR1 domains
PBLMHBDN_01361 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
PBLMHBDN_01362 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
PBLMHBDN_01363 3.9e-215 patA 2.6.1.1 E Aminotransferase
PBLMHBDN_01364 2.3e-09
PBLMHBDN_01365 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
PBLMHBDN_01366 1.4e-83 ykyB S YkyB-like protein
PBLMHBDN_01367 1.1e-239 ykuC EGP Major facilitator Superfamily
PBLMHBDN_01368 4.1e-89 ykuD S protein conserved in bacteria
PBLMHBDN_01369 9.2e-153 ykuE S Metallophosphoesterase
PBLMHBDN_01370 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PBLMHBDN_01372 3.3e-233 ykuI T Diguanylate phosphodiesterase
PBLMHBDN_01373 3.9e-37 ykuJ S protein conserved in bacteria
PBLMHBDN_01374 1.4e-92 ykuK S Ribonuclease H-like
PBLMHBDN_01375 2.1e-25 ykzF S Antirepressor AbbA
PBLMHBDN_01376 1e-75 ykuL S CBS domain
PBLMHBDN_01377 1.3e-167 ccpC K Transcriptional regulator
PBLMHBDN_01378 1.3e-89 fld C Flavodoxin
PBLMHBDN_01379 5.7e-166 ykuO
PBLMHBDN_01380 6e-79 fld C Flavodoxin
PBLMHBDN_01381 4.5e-73 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PBLMHBDN_01382 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PBLMHBDN_01383 4.8e-38 ykuS S Belongs to the UPF0180 family
PBLMHBDN_01384 3.7e-140 ykuT M Mechanosensitive ion channel
PBLMHBDN_01385 1.3e-76 ykuV CO thiol-disulfide
PBLMHBDN_01386 4.5e-98 rok K Repressor of ComK
PBLMHBDN_01387 1.8e-160 yknT
PBLMHBDN_01388 2.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PBLMHBDN_01389 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PBLMHBDN_01390 3.2e-242 moeA 2.10.1.1 H molybdopterin
PBLMHBDN_01391 3.2e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
PBLMHBDN_01392 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
PBLMHBDN_01393 1.7e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PBLMHBDN_01394 4.3e-100 yknW S Yip1 domain
PBLMHBDN_01395 4.6e-168 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBLMHBDN_01396 2e-121 macB V ABC transporter, ATP-binding protein
PBLMHBDN_01397 3e-210 yknZ V ABC transporter (permease)
PBLMHBDN_01398 1.7e-131 fruR K Transcriptional regulator
PBLMHBDN_01399 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
PBLMHBDN_01400 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PBLMHBDN_01401 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PBLMHBDN_01402 1.7e-36 ykoA
PBLMHBDN_01403 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PBLMHBDN_01404 7.6e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PBLMHBDN_01405 4.7e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PBLMHBDN_01406 5.5e-12 S Uncharacterized protein YkpC
PBLMHBDN_01407 6.9e-184 mreB D Rod-share determining protein MreBH
PBLMHBDN_01408 1.8e-44 abrB K of stationary sporulation gene expression
PBLMHBDN_01409 3.4e-244 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
PBLMHBDN_01410 1.1e-147 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
PBLMHBDN_01411 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
PBLMHBDN_01412 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PBLMHBDN_01413 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PBLMHBDN_01414 2.4e-30 ykzG S Belongs to the UPF0356 family
PBLMHBDN_01415 9.7e-146 ykrA S hydrolases of the HAD superfamily
PBLMHBDN_01416 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PBLMHBDN_01418 1.6e-101 recN L Putative cell-wall binding lipoprotein
PBLMHBDN_01419 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PBLMHBDN_01420 0.0 Q Polyketide synthase of type I
PBLMHBDN_01421 0.0 Q polyketide synthase
PBLMHBDN_01422 0.0 Q Polyketide synthase of type I
PBLMHBDN_01423 0.0 Q Polyketide synthase of type I
PBLMHBDN_01424 0.0 Q Polyketide synthase of type I
PBLMHBDN_01425 0.0 Q Polyketide synthase of type I
PBLMHBDN_01426 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
PBLMHBDN_01427 9.6e-208 V Beta-lactamase
PBLMHBDN_01428 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PBLMHBDN_01429 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PBLMHBDN_01430 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PBLMHBDN_01431 1.2e-250 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PBLMHBDN_01432 1.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
PBLMHBDN_01433 7.1e-136 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
PBLMHBDN_01434 3.2e-275 speA 4.1.1.19 E Arginine
PBLMHBDN_01435 3.5e-42 yktA S Belongs to the UPF0223 family
PBLMHBDN_01436 1.8e-118 yktB S Belongs to the UPF0637 family
PBLMHBDN_01437 6.3e-24 ykzI
PBLMHBDN_01438 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
PBLMHBDN_01439 4e-83 ykzC S Acetyltransferase (GNAT) family
PBLMHBDN_01440 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
PBLMHBDN_01441 1.8e-12 sigC S Putative zinc-finger
PBLMHBDN_01442 4.5e-37 ylaE
PBLMHBDN_01443 1.5e-23 S Family of unknown function (DUF5325)
PBLMHBDN_01444 0.0 typA T GTP-binding protein TypA
PBLMHBDN_01445 6.6e-48 ylaH S YlaH-like protein
PBLMHBDN_01446 1.4e-33 ylaI S protein conserved in bacteria
PBLMHBDN_01447 2.6e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PBLMHBDN_01448 6e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
PBLMHBDN_01449 4.2e-83 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PBLMHBDN_01450 3.9e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
PBLMHBDN_01451 8.7e-44 ylaN S Belongs to the UPF0358 family
PBLMHBDN_01452 3.2e-212 ftsW D Belongs to the SEDS family
PBLMHBDN_01453 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PBLMHBDN_01454 1.7e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PBLMHBDN_01455 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PBLMHBDN_01456 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PBLMHBDN_01457 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PBLMHBDN_01458 6.9e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PBLMHBDN_01459 7.3e-50 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PBLMHBDN_01460 2e-163 ctaG S cytochrome c oxidase
PBLMHBDN_01461 3.2e-59 ylbA S YugN-like family
PBLMHBDN_01462 2.2e-73 ylbB T COG0517 FOG CBS domain
PBLMHBDN_01463 2.3e-198 ylbC S protein with SCP PR1 domains
PBLMHBDN_01464 6.1e-54 ylbD S Putative coat protein
PBLMHBDN_01465 8.8e-37 ylbE S YlbE-like protein
PBLMHBDN_01466 1.2e-71 ylbF S Belongs to the UPF0342 family
PBLMHBDN_01467 9.4e-43 ylbG S UPF0298 protein
PBLMHBDN_01469 6e-97 rsmD 2.1.1.171 L Methyltransferase
PBLMHBDN_01470 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PBLMHBDN_01471 2.2e-216 ylbJ S Sporulation integral membrane protein YlbJ
PBLMHBDN_01472 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
PBLMHBDN_01473 3.6e-188 ylbL T Belongs to the peptidase S16 family
PBLMHBDN_01474 2.1e-227 ylbM S Belongs to the UPF0348 family
PBLMHBDN_01475 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
PBLMHBDN_01476 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PBLMHBDN_01477 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PBLMHBDN_01478 4.4e-88 ylbP K n-acetyltransferase
PBLMHBDN_01479 4.2e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PBLMHBDN_01480 9.6e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PBLMHBDN_01481 1.2e-77 mraZ K Belongs to the MraZ family
PBLMHBDN_01482 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PBLMHBDN_01483 2.9e-52 ftsL D Essential cell division protein
PBLMHBDN_01484 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PBLMHBDN_01485 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
PBLMHBDN_01486 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PBLMHBDN_01487 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PBLMHBDN_01488 8.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PBLMHBDN_01489 2.2e-185 spoVE D Belongs to the SEDS family
PBLMHBDN_01490 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PBLMHBDN_01491 1.8e-167 murB 1.3.1.98 M cell wall formation
PBLMHBDN_01492 4.8e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PBLMHBDN_01493 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PBLMHBDN_01494 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PBLMHBDN_01495 0.0 bpr O COG1404 Subtilisin-like serine proteases
PBLMHBDN_01496 2.4e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PBLMHBDN_01497 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBLMHBDN_01498 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBLMHBDN_01499 1.6e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PBLMHBDN_01500 3.7e-251 argE 3.5.1.16 E Acetylornithine deacetylase
PBLMHBDN_01501 2.2e-38 ylmC S sporulation protein
PBLMHBDN_01502 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
PBLMHBDN_01503 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PBLMHBDN_01504 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PBLMHBDN_01505 5.2e-41 yggT S membrane
PBLMHBDN_01506 2.1e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
PBLMHBDN_01507 8.9e-68 divIVA D Cell division initiation protein
PBLMHBDN_01508 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PBLMHBDN_01509 1.2e-61 dksA T COG1734 DnaK suppressor protein
PBLMHBDN_01510 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PBLMHBDN_01511 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PBLMHBDN_01512 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PBLMHBDN_01513 3e-232 pyrP F Xanthine uracil
PBLMHBDN_01514 4.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PBLMHBDN_01515 1.2e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PBLMHBDN_01516 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PBLMHBDN_01517 0.0 carB 6.3.5.5 F Belongs to the CarB family
PBLMHBDN_01518 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PBLMHBDN_01519 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PBLMHBDN_01520 6.1e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PBLMHBDN_01521 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PBLMHBDN_01523 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
PBLMHBDN_01524 1.1e-176 cysP P phosphate transporter
PBLMHBDN_01525 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
PBLMHBDN_01526 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
PBLMHBDN_01527 2.2e-142 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
PBLMHBDN_01528 9.9e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
PBLMHBDN_01529 9.3e-78 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
PBLMHBDN_01530 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PBLMHBDN_01531 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
PBLMHBDN_01532 5e-154 yloC S stress-induced protein
PBLMHBDN_01533 1.5e-40 ylzA S Belongs to the UPF0296 family
PBLMHBDN_01534 2.3e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PBLMHBDN_01535 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PBLMHBDN_01536 9.7e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PBLMHBDN_01537 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PBLMHBDN_01538 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PBLMHBDN_01539 1.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PBLMHBDN_01540 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PBLMHBDN_01541 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PBLMHBDN_01542 2.3e-139 stp 3.1.3.16 T phosphatase
PBLMHBDN_01543 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PBLMHBDN_01544 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PBLMHBDN_01545 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PBLMHBDN_01546 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
PBLMHBDN_01547 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PBLMHBDN_01548 5.5e-59 asp S protein conserved in bacteria
PBLMHBDN_01549 1.4e-303 yloV S kinase related to dihydroxyacetone kinase
PBLMHBDN_01550 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
PBLMHBDN_01551 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
PBLMHBDN_01552 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PBLMHBDN_01553 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PBLMHBDN_01554 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PBLMHBDN_01555 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PBLMHBDN_01556 4.6e-129 IQ reductase
PBLMHBDN_01557 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PBLMHBDN_01558 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PBLMHBDN_01559 0.0 smc D Required for chromosome condensation and partitioning
PBLMHBDN_01560 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PBLMHBDN_01561 7.9e-140 S Phosphotransferase enzyme family
PBLMHBDN_01562 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PBLMHBDN_01563 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PBLMHBDN_01564 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PBLMHBDN_01565 1.7e-35 ylqC S Belongs to the UPF0109 family
PBLMHBDN_01566 1.3e-61 ylqD S YlqD protein
PBLMHBDN_01567 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PBLMHBDN_01568 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PBLMHBDN_01569 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PBLMHBDN_01570 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PBLMHBDN_01571 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PBLMHBDN_01572 9.5e-303 ylqG
PBLMHBDN_01573 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
PBLMHBDN_01574 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PBLMHBDN_01575 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PBLMHBDN_01576 1.6e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
PBLMHBDN_01577 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PBLMHBDN_01578 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PBLMHBDN_01579 7.2e-172 xerC L tyrosine recombinase XerC
PBLMHBDN_01580 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PBLMHBDN_01581 4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PBLMHBDN_01582 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PBLMHBDN_01583 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PBLMHBDN_01584 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
PBLMHBDN_01585 2.5e-31 fliE N Flagellar hook-basal body
PBLMHBDN_01586 1.4e-263 fliF N The M ring may be actively involved in energy transduction
PBLMHBDN_01587 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PBLMHBDN_01588 2.2e-86 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
PBLMHBDN_01589 1.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PBLMHBDN_01590 2e-71 fliJ N Flagellar biosynthesis chaperone
PBLMHBDN_01591 1.3e-47 ylxF S MgtE intracellular N domain
PBLMHBDN_01592 8.8e-203 fliK N Flagellar hook-length control protein
PBLMHBDN_01593 4.1e-72 flgD N Flagellar basal body rod modification protein
PBLMHBDN_01594 5.7e-138 flgG N Flagellar basal body rod
PBLMHBDN_01595 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
PBLMHBDN_01596 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PBLMHBDN_01597 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PBLMHBDN_01598 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
PBLMHBDN_01599 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
PBLMHBDN_01600 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
PBLMHBDN_01601 2e-37 fliQ N Role in flagellar biosynthesis
PBLMHBDN_01602 5.2e-131 fliR N Flagellar biosynthetic protein FliR
PBLMHBDN_01603 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PBLMHBDN_01604 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PBLMHBDN_01605 2.2e-191 flhF N Flagellar biosynthesis regulator FlhF
PBLMHBDN_01606 2.4e-156 flhG D Belongs to the ParA family
PBLMHBDN_01607 1.5e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PBLMHBDN_01608 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
PBLMHBDN_01609 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
PBLMHBDN_01610 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PBLMHBDN_01611 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PBLMHBDN_01612 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBLMHBDN_01613 4e-49 ylxL
PBLMHBDN_01614 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
PBLMHBDN_01615 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PBLMHBDN_01616 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PBLMHBDN_01617 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PBLMHBDN_01618 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PBLMHBDN_01619 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
PBLMHBDN_01620 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PBLMHBDN_01621 1.5e-233 rasP M zinc metalloprotease
PBLMHBDN_01622 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PBLMHBDN_01623 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PBLMHBDN_01624 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
PBLMHBDN_01625 5.4e-206 nusA K Participates in both transcription termination and antitermination
PBLMHBDN_01626 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
PBLMHBDN_01627 1.8e-47 ylxQ J ribosomal protein
PBLMHBDN_01628 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PBLMHBDN_01629 3.9e-44 ylxP S protein conserved in bacteria
PBLMHBDN_01630 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PBLMHBDN_01631 3.6e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PBLMHBDN_01632 6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PBLMHBDN_01633 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PBLMHBDN_01634 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PBLMHBDN_01635 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
PBLMHBDN_01636 1.2e-233 pepR S Belongs to the peptidase M16 family
PBLMHBDN_01637 2.6e-42 ymxH S YlmC YmxH family
PBLMHBDN_01638 4.7e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
PBLMHBDN_01639 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PBLMHBDN_01640 5.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PBLMHBDN_01641 2.1e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
PBLMHBDN_01642 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBLMHBDN_01643 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PBLMHBDN_01644 2.3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
PBLMHBDN_01645 6.3e-31 S YlzJ-like protein
PBLMHBDN_01646 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PBLMHBDN_01647 1.2e-132 ymfC K Transcriptional regulator
PBLMHBDN_01648 3e-227 ymfD EGP Major facilitator Superfamily
PBLMHBDN_01649 2.1e-76 K helix_turn_helix multiple antibiotic resistance protein
PBLMHBDN_01650 0.0 ydgH S drug exporters of the RND superfamily
PBLMHBDN_01651 4.4e-236 ymfF S Peptidase M16
PBLMHBDN_01652 1.3e-240 ymfH S zinc protease
PBLMHBDN_01653 6.6e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PBLMHBDN_01654 2.2e-41 ymfJ S Protein of unknown function (DUF3243)
PBLMHBDN_01655 1e-142 ymfK S Protein of unknown function (DUF3388)
PBLMHBDN_01656 2.5e-124 ymfM S protein conserved in bacteria
PBLMHBDN_01657 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PBLMHBDN_01658 7.1e-231 cinA 3.5.1.42 S Belongs to the CinA family
PBLMHBDN_01659 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PBLMHBDN_01660 1.1e-193 pbpX V Beta-lactamase
PBLMHBDN_01661 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
PBLMHBDN_01662 4.9e-153 ymdB S protein conserved in bacteria
PBLMHBDN_01663 1.2e-36 spoVS S Stage V sporulation protein S
PBLMHBDN_01664 4.8e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
PBLMHBDN_01665 7.4e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PBLMHBDN_01666 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBLMHBDN_01667 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PBLMHBDN_01668 1.7e-88 cotE S Spore coat protein
PBLMHBDN_01669 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PBLMHBDN_01670 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PBLMHBDN_01672 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
PBLMHBDN_01673 7e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PBLMHBDN_01674 1.1e-183 pksD Q Acyl transferase domain
PBLMHBDN_01675 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PBLMHBDN_01676 5.5e-34 acpK IQ Phosphopantetheine attachment site
PBLMHBDN_01677 1.5e-241 pksG 2.3.3.10 I synthase
PBLMHBDN_01678 1.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
PBLMHBDN_01679 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
PBLMHBDN_01680 0.0 rhiB IQ polyketide synthase
PBLMHBDN_01681 0.0 Q Polyketide synthase of type I
PBLMHBDN_01682 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
PBLMHBDN_01683 0.0 dhbF IQ polyketide synthase
PBLMHBDN_01684 0.0 pks13 HQ Beta-ketoacyl synthase
PBLMHBDN_01685 3.8e-229 cypA C Cytochrome P450
PBLMHBDN_01686 1.9e-77 nucB M Deoxyribonuclease NucA/NucB
PBLMHBDN_01687 2.3e-117 yoaK S Membrane
PBLMHBDN_01688 1.2e-61 ymzB
PBLMHBDN_01689 1.7e-254 aprX O Belongs to the peptidase S8 family
PBLMHBDN_01690 3e-125 ymaC S Replication protein
PBLMHBDN_01691 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
PBLMHBDN_01692 2.6e-53 ebrB P Small Multidrug Resistance protein
PBLMHBDN_01693 2.6e-47 ebrA P Small Multidrug Resistance protein
PBLMHBDN_01695 9.2e-47 ymaF S YmaF family
PBLMHBDN_01696 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PBLMHBDN_01697 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PBLMHBDN_01698 3e-41
PBLMHBDN_01699 1.8e-20 ymzA
PBLMHBDN_01700 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
PBLMHBDN_01701 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PBLMHBDN_01702 1.4e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PBLMHBDN_01703 2.2e-108 ymaB S MutT family
PBLMHBDN_01704 4.7e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PBLMHBDN_01705 1.3e-176 spoVK O stage V sporulation protein K
PBLMHBDN_01706 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PBLMHBDN_01707 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PBLMHBDN_01708 4.3e-68 glnR K transcriptional
PBLMHBDN_01709 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
PBLMHBDN_01710 8.6e-24
PBLMHBDN_01711 9.2e-94
PBLMHBDN_01713 3.2e-11
PBLMHBDN_01715 1.2e-40 S Protein of unknown function (DUF2568)
PBLMHBDN_01716 3.2e-09 T Histidine kinase
PBLMHBDN_01717 7.4e-25 T Histidine kinase
PBLMHBDN_01718 4.3e-208 mrjp G Major royal jelly protein
PBLMHBDN_01719 4.9e-249 xynT G MFS/sugar transport protein
PBLMHBDN_01720 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
PBLMHBDN_01721 2.4e-209 xylR GK ROK family
PBLMHBDN_01722 1.2e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
PBLMHBDN_01723 7.1e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
PBLMHBDN_01724 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
PBLMHBDN_01728 7e-17
PBLMHBDN_01729 2e-121 K WYL domain
PBLMHBDN_01730 4.5e-67 S DinB family
PBLMHBDN_01731 1.1e-184 adhP 1.1.1.1 C alcohol dehydrogenase
PBLMHBDN_01733 1.2e-41 yoaP 3.1.3.18 K YoaP-like
PBLMHBDN_01734 2.4e-86 yoaP 3.1.3.18 K YoaP-like
PBLMHBDN_01735 6.3e-99 J Acetyltransferase (GNAT) domain
PBLMHBDN_01737 1.3e-59
PBLMHBDN_01739 1.1e-115 ynaE S Domain of unknown function (DUF3885)
PBLMHBDN_01740 3.9e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBLMHBDN_01741 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
PBLMHBDN_01743 1.1e-63 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PBLMHBDN_01744 4.3e-92 yvgO
PBLMHBDN_01746 0.0 yobO M Pectate lyase superfamily protein
PBLMHBDN_01747 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
PBLMHBDN_01748 2.6e-141 yndL S Replication protein
PBLMHBDN_01749 9.1e-08
PBLMHBDN_01750 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
PBLMHBDN_01751 1.2e-71 yndM S Protein of unknown function (DUF2512)
PBLMHBDN_01752 2.1e-12 yoaW
PBLMHBDN_01753 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PBLMHBDN_01754 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PBLMHBDN_01755 3.5e-112 yneB L resolvase
PBLMHBDN_01756 9.8e-33 ynzC S UPF0291 protein
PBLMHBDN_01757 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PBLMHBDN_01758 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
PBLMHBDN_01759 2.3e-28 yneF S UPF0154 protein
PBLMHBDN_01760 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
PBLMHBDN_01761 2.3e-125 ccdA O cytochrome c biogenesis protein
PBLMHBDN_01762 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
PBLMHBDN_01763 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
PBLMHBDN_01764 2.5e-74 yneK S Protein of unknown function (DUF2621)
PBLMHBDN_01765 1.1e-62 hspX O Spore coat protein
PBLMHBDN_01766 2.3e-19 sspP S Belongs to the SspP family
PBLMHBDN_01767 7.5e-15 sspO S Belongs to the SspO family
PBLMHBDN_01768 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PBLMHBDN_01769 5.3e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PBLMHBDN_01771 7.1e-18 tlp S Belongs to the Tlp family
PBLMHBDN_01772 8.3e-75 yneP S Thioesterase-like superfamily
PBLMHBDN_01773 1.4e-52 yneQ
PBLMHBDN_01774 1.1e-49 yneR S Belongs to the HesB IscA family
PBLMHBDN_01775 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PBLMHBDN_01776 1.5e-68 yccU S CoA-binding protein
PBLMHBDN_01777 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PBLMHBDN_01778 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PBLMHBDN_01779 6e-13
PBLMHBDN_01780 5.1e-41 ynfC
PBLMHBDN_01781 1.2e-245 agcS E Sodium alanine symporter
PBLMHBDN_01782 9.1e-178 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
PBLMHBDN_01783 3.4e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
PBLMHBDN_01784 1.5e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
PBLMHBDN_01785 4.1e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
PBLMHBDN_01786 1.1e-145 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PBLMHBDN_01787 4.3e-178 kdgR_1 K transcriptional
PBLMHBDN_01788 1.3e-219 exuT G Sugar (and other) transporter
PBLMHBDN_01789 5.4e-155 yndG S DoxX-like family
PBLMHBDN_01790 4.3e-80 yndH S Domain of unknown function (DUF4166)
PBLMHBDN_01791 4.8e-296 yndJ S YndJ-like protein
PBLMHBDN_01792 2.7e-29 yxlH EGP Major facilitator Superfamily
PBLMHBDN_01794 1.7e-58 S Platelet-activating factor acetylhydrolase, isoform II
PBLMHBDN_01795 7.9e-47 S Platelet-activating factor acetylhydrolase, isoform II
PBLMHBDN_01796 3.5e-285 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
PBLMHBDN_01797 1.2e-49 S Domain of unknown function (DUF4870)
PBLMHBDN_01798 6.1e-231 T PhoQ Sensor
PBLMHBDN_01799 4.6e-126 T Transcriptional regulatory protein, C terminal
PBLMHBDN_01800 8.2e-251 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
PBLMHBDN_01801 8e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
PBLMHBDN_01802 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_01803 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_01804 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_01805 5.8e-214 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PBLMHBDN_01806 6.4e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PBLMHBDN_01807 7.1e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PBLMHBDN_01808 9.9e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PBLMHBDN_01809 4.2e-251 yxjC EG COG2610 H gluconate symporter and related permeases
PBLMHBDN_01810 5.6e-217 bioI 1.14.14.46 C Cytochrome P450
PBLMHBDN_01811 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PBLMHBDN_01812 4.1e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PBLMHBDN_01813 9e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PBLMHBDN_01814 1.1e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
PBLMHBDN_01815 2e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
PBLMHBDN_01816 9.6e-68 yngA S membrane
PBLMHBDN_01817 2.6e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PBLMHBDN_01818 3.2e-104 yngC S SNARE associated Golgi protein
PBLMHBDN_01819 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PBLMHBDN_01820 3.1e-139 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
PBLMHBDN_01821 5.2e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
PBLMHBDN_01822 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
PBLMHBDN_01823 2.1e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
PBLMHBDN_01824 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PBLMHBDN_01825 3.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
PBLMHBDN_01826 3e-300 yngK T Glycosyl hydrolase-like 10
PBLMHBDN_01827 1.6e-64 yngL S Protein of unknown function (DUF1360)
PBLMHBDN_01828 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
PBLMHBDN_01829 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_01830 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_01831 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_01832 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_01833 1.5e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
PBLMHBDN_01834 3.5e-185 yoxA 5.1.3.3 G Aldose 1-epimerase
PBLMHBDN_01835 6.7e-246 yoeA V MATE efflux family protein
PBLMHBDN_01836 3.6e-94 yoeB S IseA DL-endopeptidase inhibitor
PBLMHBDN_01838 3.5e-97 L Integrase
PBLMHBDN_01839 1.8e-34 yoeD G Helix-turn-helix domain
PBLMHBDN_01840 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PBLMHBDN_01841 3.4e-198 ybcL EGP Major facilitator Superfamily
PBLMHBDN_01842 1.8e-50 ybzH K Helix-turn-helix domain
PBLMHBDN_01844 4.1e-153 gltR1 K Transcriptional regulator
PBLMHBDN_01845 2.1e-182 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PBLMHBDN_01846 7.2e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PBLMHBDN_01847 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
PBLMHBDN_01848 1.3e-149 gltC K Transcriptional regulator
PBLMHBDN_01849 6.2e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PBLMHBDN_01850 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PBLMHBDN_01851 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PBLMHBDN_01852 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PBLMHBDN_01853 2.4e-39 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PBLMHBDN_01854 3.9e-131 yoxB
PBLMHBDN_01855 7.4e-204 yoaB EGP Major facilitator Superfamily
PBLMHBDN_01856 5e-268 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
PBLMHBDN_01857 5.7e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBLMHBDN_01858 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PBLMHBDN_01859 1.2e-24 yoaF
PBLMHBDN_01861 4.5e-95 hpr K helix_turn_helix multiple antibiotic resistance protein
PBLMHBDN_01862 7.4e-43
PBLMHBDN_01863 2.1e-129 IQ Enoyl-(Acyl carrier protein) reductase
PBLMHBDN_01864 3.4e-61 ykvN K Transcriptional regulator
PBLMHBDN_01865 3.2e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
PBLMHBDN_01866 1e-133 yobQ K helix_turn_helix, arabinose operon control protein
PBLMHBDN_01867 7.7e-92 yobS K Transcriptional regulator
PBLMHBDN_01868 1.1e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
PBLMHBDN_01869 2.7e-91 yobW
PBLMHBDN_01870 1.7e-54 czrA K transcriptional
PBLMHBDN_01871 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PBLMHBDN_01872 3.6e-91 yozB S membrane
PBLMHBDN_01873 1.3e-137 yocB J Protein required for attachment to host cells
PBLMHBDN_01874 1.6e-93 yocC
PBLMHBDN_01875 5.5e-186 yocD 3.4.17.13 V peptidase S66
PBLMHBDN_01877 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
PBLMHBDN_01878 0.0 recQ 3.6.4.12 L DNA helicase
PBLMHBDN_01879 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PBLMHBDN_01881 1.9e-54 dksA T general stress protein
PBLMHBDN_01882 7.8e-10 yocL
PBLMHBDN_01883 7.5e-09
PBLMHBDN_01884 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
PBLMHBDN_01885 3.8e-44 yozN
PBLMHBDN_01886 8.5e-37 yocN
PBLMHBDN_01887 2.4e-56 yozO S Bacterial PH domain
PBLMHBDN_01889 1e-30 yozC
PBLMHBDN_01890 9.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
PBLMHBDN_01891 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
PBLMHBDN_01892 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
PBLMHBDN_01893 8.7e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PBLMHBDN_01894 3e-160 yocS S -transporter
PBLMHBDN_01895 7.2e-138 S Metallo-beta-lactamase superfamily
PBLMHBDN_01896 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PBLMHBDN_01897 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PBLMHBDN_01898 0.0 yojO P Von Willebrand factor
PBLMHBDN_01899 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
PBLMHBDN_01900 4.8e-75 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PBLMHBDN_01901 3.2e-21 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PBLMHBDN_01902 2.6e-225 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PBLMHBDN_01903 6.9e-223 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
PBLMHBDN_01904 6.3e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PBLMHBDN_01906 6.1e-236 norM V Multidrug efflux pump
PBLMHBDN_01907 3.5e-76 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PBLMHBDN_01908 4.1e-105 S aspartate phosphatase
PBLMHBDN_01911 1.3e-70 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PBLMHBDN_01912 8.4e-67 S Pfam:Phage_holin_4_1
PBLMHBDN_01915 1.9e-164 S Domain of unknown function (DUF2479)
PBLMHBDN_01916 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
PBLMHBDN_01917 1.7e-227 NU Prophage endopeptidase tail
PBLMHBDN_01918 4.9e-111 S Phage tail protein
PBLMHBDN_01919 0.0 S peptidoglycan catabolic process
PBLMHBDN_01920 2.5e-11
PBLMHBDN_01921 3.5e-23
PBLMHBDN_01922 9.9e-61
PBLMHBDN_01923 1.3e-29
PBLMHBDN_01924 4.2e-49 S Bacteriophage HK97-gp10, putative tail-component
PBLMHBDN_01925 4.7e-15 S Phage head-tail joining protein
PBLMHBDN_01926 9.4e-24 S Phage gp6-like head-tail connector protein
PBLMHBDN_01927 1.1e-35 S peptidoglycan catabolic process
PBLMHBDN_01929 2.5e-217 S peptidase activity
PBLMHBDN_01930 3e-113 S peptidase activity
PBLMHBDN_01931 3.8e-240 S Phage portal protein
PBLMHBDN_01932 1.4e-10
PBLMHBDN_01933 2.2e-230 S Phage Terminase
PBLMHBDN_01934 3.9e-87 S Phage terminase, small subunit
PBLMHBDN_01935 1.3e-66 S HNH endonuclease
PBLMHBDN_01936 4.8e-37
PBLMHBDN_01937 3.4e-39 S Protein of unknown function (DUF2971)
PBLMHBDN_01938 1.7e-12 K Transcriptional regulator
PBLMHBDN_01940 1.4e-76 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PBLMHBDN_01941 1.3e-25 S Phage-like element PBSX protein XtrA
PBLMHBDN_01942 1.3e-23
PBLMHBDN_01943 5.7e-170 dnaB 3.6.4.12 L replicative DNA helicase
PBLMHBDN_01944 2.5e-24 S Loader and inhibitor of phage G40P
PBLMHBDN_01945 2.5e-101 L DnaD domain protein
PBLMHBDN_01947 1.7e-10
PBLMHBDN_01948 8.7e-71 S Phage regulatory protein Rha (Phage_pRha)
PBLMHBDN_01950 6.1e-13 S Uncharacterized protein YqaH
PBLMHBDN_01952 1.7e-28
PBLMHBDN_01953 3e-17
PBLMHBDN_01954 2.8e-27 K Helix-turn-helix XRE-family like proteins
PBLMHBDN_01955 9.3e-43 E Zn peptidase
PBLMHBDN_01956 5.7e-134 L Belongs to the 'phage' integrase family
PBLMHBDN_01957 2e-65 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PBLMHBDN_01958 5.6e-126 yojG S deacetylase
PBLMHBDN_01959 3.7e-60 yojF S Protein of unknown function (DUF1806)
PBLMHBDN_01960 4.9e-23
PBLMHBDN_01961 1.1e-161 rarD S -transporter
PBLMHBDN_01962 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
PBLMHBDN_01964 7.7e-67 yodA S tautomerase
PBLMHBDN_01965 6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
PBLMHBDN_01966 3e-56 yodB K transcriptional
PBLMHBDN_01967 4.5e-106 yodC C nitroreductase
PBLMHBDN_01968 3.7e-108 mhqD S Carboxylesterase
PBLMHBDN_01969 1e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
PBLMHBDN_01970 1.4e-19 S Protein of unknown function (DUF3311)
PBLMHBDN_01971 7.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBLMHBDN_01972 1.3e-276 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
PBLMHBDN_01973 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PBLMHBDN_01974 2.6e-132 yydK K Transcriptional regulator
PBLMHBDN_01975 3.9e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
PBLMHBDN_01976 1.4e-127 yodH Q Methyltransferase
PBLMHBDN_01977 1.9e-21 yodI
PBLMHBDN_01978 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PBLMHBDN_01979 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
PBLMHBDN_01981 3.3e-55 yodL S YodL-like
PBLMHBDN_01982 1.4e-102 yodM 3.6.1.27 I Acid phosphatase homologues
PBLMHBDN_01983 6.2e-24 yozD S YozD-like protein
PBLMHBDN_01985 1.7e-125 yodN
PBLMHBDN_01986 9.1e-36 yozE S Belongs to the UPF0346 family
PBLMHBDN_01987 9.2e-46 yokU S YokU-like protein, putative antitoxin
PBLMHBDN_01988 2.3e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
PBLMHBDN_01989 1.9e-158 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
PBLMHBDN_01990 2e-252 yodQ 3.5.1.16 E Acetylornithine deacetylase
PBLMHBDN_01991 8e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PBLMHBDN_01992 7.1e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PBLMHBDN_01993 7.1e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PBLMHBDN_01994 4.1e-64 yosT L Bacterial transcription activator, effector binding domain
PBLMHBDN_01996 1.4e-144 yiiD K acetyltransferase
PBLMHBDN_01997 2e-241 cgeD M maturation of the outermost layer of the spore
PBLMHBDN_01998 1.2e-40 cgeC
PBLMHBDN_01999 1.6e-52 cgeA
PBLMHBDN_02000 7.5e-164 cgeB S Spore maturation protein
PBLMHBDN_02001 1.5e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
PBLMHBDN_02002 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
PBLMHBDN_02008 1.7e-77
PBLMHBDN_02009 2.5e-22 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
PBLMHBDN_02010 2.6e-08
PBLMHBDN_02013 1.1e-75 yoqH M LysM domain
PBLMHBDN_02014 7.8e-177 S aspartate phosphatase
PBLMHBDN_02017 2.8e-113 3.4.24.40 S amine dehydrogenase activity
PBLMHBDN_02019 2e-08 S Domain of unknown function (DUF4879)
PBLMHBDN_02020 4e-23
PBLMHBDN_02021 6.6e-30 S Acetyltransferase (GNAT) domain
PBLMHBDN_02022 1.5e-87 yokK S SMI1 / KNR4 family
PBLMHBDN_02023 7.5e-53 S SMI1-KNR4 cell-wall
PBLMHBDN_02024 2.8e-289 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PBLMHBDN_02025 2.7e-86 G SMI1-KNR4 cell-wall
PBLMHBDN_02026 2.1e-76 yokF 3.1.31.1 L RNA catabolic process
PBLMHBDN_02029 4.9e-304 yokA L Recombinase
PBLMHBDN_02030 2.6e-103 4.2.1.115 GM Polysaccharide biosynthesis protein
PBLMHBDN_02031 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PBLMHBDN_02032 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBLMHBDN_02033 1.4e-66 ypoP K transcriptional
PBLMHBDN_02034 1.8e-96 ypmS S protein conserved in bacteria
PBLMHBDN_02035 2.4e-133 ypmR E GDSL-like Lipase/Acylhydrolase
PBLMHBDN_02036 1.1e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PBLMHBDN_02037 3.2e-37 ypmP S Protein of unknown function (DUF2535)
PBLMHBDN_02038 3.7e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PBLMHBDN_02039 8.3e-174 pspF K Transcriptional regulator
PBLMHBDN_02040 1.6e-109 hlyIII S protein, Hemolysin III
PBLMHBDN_02041 6.7e-113 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PBLMHBDN_02042 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PBLMHBDN_02043 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PBLMHBDN_02044 8.5e-113 ypjP S YpjP-like protein
PBLMHBDN_02045 3.3e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
PBLMHBDN_02046 1e-75 yphP S Belongs to the UPF0403 family
PBLMHBDN_02047 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PBLMHBDN_02048 2.2e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
PBLMHBDN_02049 3.1e-99 ypgQ S phosphohydrolase
PBLMHBDN_02050 1.6e-85 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PBLMHBDN_02051 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PBLMHBDN_02052 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
PBLMHBDN_02053 1e-30 cspD K Cold-shock protein
PBLMHBDN_02054 1.3e-11 degR
PBLMHBDN_02055 1.2e-36 S Protein of unknown function (DUF2564)
PBLMHBDN_02056 1.5e-28 ypeQ S Zinc-finger
PBLMHBDN_02057 9.1e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
PBLMHBDN_02058 9.9e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PBLMHBDN_02059 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
PBLMHBDN_02061 3.5e-163 polA 2.7.7.7 L 5'3' exonuclease
PBLMHBDN_02063 2.2e-38 ypbS S Protein of unknown function (DUF2533)
PBLMHBDN_02064 0.0 ypbR S Dynamin family
PBLMHBDN_02065 1.1e-89 ypbQ S protein conserved in bacteria
PBLMHBDN_02066 6.1e-202 bcsA Q Naringenin-chalcone synthase
PBLMHBDN_02067 1.3e-105 J Acetyltransferase (GNAT) domain
PBLMHBDN_02068 6e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
PBLMHBDN_02070 3.9e-22 ydfR S Protein of unknown function (DUF421)
PBLMHBDN_02071 4.4e-33 ydfR S Protein of unknown function (DUF421)
PBLMHBDN_02072 1.9e-98 yrdC 3.5.1.19 Q Isochorismatase family
PBLMHBDN_02074 1.5e-72 S Protein of unknown function (DUF3800)
PBLMHBDN_02075 3.5e-27 K Helix-turn-helix domain
PBLMHBDN_02076 1.4e-22
PBLMHBDN_02077 3.4e-86 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
PBLMHBDN_02080 2.4e-71 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PBLMHBDN_02081 1e-56 S Pfam:Phage_holin_4_1
PBLMHBDN_02083 4e-09
PBLMHBDN_02084 4.1e-94
PBLMHBDN_02085 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
PBLMHBDN_02086 4.5e-228 NU Prophage endopeptidase tail
PBLMHBDN_02087 5.5e-102 S Phage tail protein
PBLMHBDN_02088 0.0 D phage tail tape measure protein
PBLMHBDN_02090 3e-81 S Phage tail tube protein
PBLMHBDN_02092 7.4e-49 S Bacteriophage HK97-gp10, putative tail-component
PBLMHBDN_02093 2.9e-40 S Phage head-tail joining protein
PBLMHBDN_02094 4.5e-38 S Phage gp6-like head-tail connector protein
PBLMHBDN_02095 3.1e-23
PBLMHBDN_02096 5.9e-156 gp36 S capsid protein
PBLMHBDN_02097 1.1e-83 S peptidase activity
PBLMHBDN_02098 1.1e-170 S Phage portal protein
PBLMHBDN_02099 8.9e-301 S Terminase
PBLMHBDN_02100 2.2e-77 L phage terminase small subunit
PBLMHBDN_02103 1.5e-16 K Transcriptional regulator
PBLMHBDN_02107 9.3e-68 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PBLMHBDN_02109 2.7e-11
PBLMHBDN_02111 3.4e-21 yqaO S Phage-like element PBSX protein XtrA
PBLMHBDN_02113 4.2e-58 rusA L Endodeoxyribonuclease RusA
PBLMHBDN_02115 2.8e-118 xkdC L IstB-like ATP binding protein
PBLMHBDN_02116 1e-77 3.1.3.16 L DnaD domain protein
PBLMHBDN_02118 3.9e-61 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
PBLMHBDN_02119 7.3e-100
PBLMHBDN_02123 2e-87
PBLMHBDN_02124 1.2e-71 S DNA binding
PBLMHBDN_02125 6.5e-32
PBLMHBDN_02126 1.1e-09 K transcriptional regulator with C-terminal CBS domains
PBLMHBDN_02127 9.6e-14 K Helix-turn-helix XRE-family like proteins
PBLMHBDN_02128 8e-139 L Belongs to the 'phage' integrase family
PBLMHBDN_02129 2.2e-235 pbuX F xanthine
PBLMHBDN_02130 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PBLMHBDN_02131 1.3e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PBLMHBDN_02132 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
PBLMHBDN_02134 6.6e-22 S YpzG-like protein
PBLMHBDN_02135 7.9e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PBLMHBDN_02136 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PBLMHBDN_02137 1.1e-98 ypsA S Belongs to the UPF0398 family
PBLMHBDN_02138 9.9e-33 cotD S Inner spore coat protein D
PBLMHBDN_02140 7.3e-212 yprB L RNase_H superfamily
PBLMHBDN_02141 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PBLMHBDN_02142 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
PBLMHBDN_02143 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
PBLMHBDN_02144 2.1e-49 yppG S YppG-like protein
PBLMHBDN_02146 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
PBLMHBDN_02149 8.3e-187 yppC S Protein of unknown function (DUF2515)
PBLMHBDN_02150 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PBLMHBDN_02151 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PBLMHBDN_02152 1.7e-90 ypoC
PBLMHBDN_02153 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PBLMHBDN_02154 3e-130 dnaD L DNA replication protein DnaD
PBLMHBDN_02155 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
PBLMHBDN_02156 9.7e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PBLMHBDN_02157 1.5e-80 ypmB S protein conserved in bacteria
PBLMHBDN_02158 6.7e-23 ypmA S Protein of unknown function (DUF4264)
PBLMHBDN_02159 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PBLMHBDN_02160 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PBLMHBDN_02161 9.4e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PBLMHBDN_02162 9.5e-147 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PBLMHBDN_02163 5.3e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PBLMHBDN_02164 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PBLMHBDN_02165 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
PBLMHBDN_02166 1.9e-132 bshB1 S proteins, LmbE homologs
PBLMHBDN_02167 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
PBLMHBDN_02168 1.2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PBLMHBDN_02169 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
PBLMHBDN_02170 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
PBLMHBDN_02171 2.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
PBLMHBDN_02172 9.5e-141 ypjB S sporulation protein
PBLMHBDN_02173 2.9e-105 ypjA S membrane
PBLMHBDN_02174 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
PBLMHBDN_02175 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
PBLMHBDN_02176 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
PBLMHBDN_02177 3.2e-77 ypiF S Protein of unknown function (DUF2487)
PBLMHBDN_02178 2.1e-99 ypiB S Belongs to the UPF0302 family
PBLMHBDN_02179 9.1e-234 S COG0457 FOG TPR repeat
PBLMHBDN_02180 8.1e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PBLMHBDN_02181 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PBLMHBDN_02182 1.9e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PBLMHBDN_02183 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PBLMHBDN_02184 5.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PBLMHBDN_02185 7.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
PBLMHBDN_02186 1.5e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PBLMHBDN_02187 2.4e-152 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PBLMHBDN_02188 4.6e-288 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PBLMHBDN_02189 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PBLMHBDN_02190 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PBLMHBDN_02191 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PBLMHBDN_02192 3e-139 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
PBLMHBDN_02193 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PBLMHBDN_02194 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PBLMHBDN_02195 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PBLMHBDN_02196 1.4e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PBLMHBDN_02197 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PBLMHBDN_02198 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
PBLMHBDN_02199 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PBLMHBDN_02200 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PBLMHBDN_02201 1.1e-133 yphF
PBLMHBDN_02202 3.3e-16 yphE S Protein of unknown function (DUF2768)
PBLMHBDN_02203 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PBLMHBDN_02204 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PBLMHBDN_02205 7.2e-104 yphA
PBLMHBDN_02206 4.7e-08 S YpzI-like protein
PBLMHBDN_02207 1.7e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PBLMHBDN_02208 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
PBLMHBDN_02209 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PBLMHBDN_02210 1.4e-12 S Family of unknown function (DUF5359)
PBLMHBDN_02211 1.4e-60 ypfA M Flagellar protein YcgR
PBLMHBDN_02212 1e-251 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
PBLMHBDN_02213 3e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
PBLMHBDN_02214 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
PBLMHBDN_02215 3.4e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
PBLMHBDN_02216 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
PBLMHBDN_02217 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PBLMHBDN_02218 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
PBLMHBDN_02219 1.3e-84 ypbF S Protein of unknown function (DUF2663)
PBLMHBDN_02220 2.2e-73 ypbE M Lysin motif
PBLMHBDN_02221 4e-99 ypbD S metal-dependent membrane protease
PBLMHBDN_02222 3e-270 recQ 3.6.4.12 L DNA helicase
PBLMHBDN_02223 1.5e-194 ypbB 5.1.3.1 S protein conserved in bacteria
PBLMHBDN_02224 3.6e-41 fer C Ferredoxin
PBLMHBDN_02225 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PBLMHBDN_02226 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBLMHBDN_02227 6.3e-191 rsiX
PBLMHBDN_02228 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
PBLMHBDN_02229 0.0 resE 2.7.13.3 T Histidine kinase
PBLMHBDN_02230 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PBLMHBDN_02231 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PBLMHBDN_02232 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
PBLMHBDN_02233 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PBLMHBDN_02234 1.3e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PBLMHBDN_02235 1.3e-88 spmB S Spore maturation protein
PBLMHBDN_02236 2e-103 spmA S Spore maturation protein
PBLMHBDN_02237 1.5e-214 dacB 3.4.16.4 M Belongs to the peptidase S11 family
PBLMHBDN_02238 3.8e-93 ypuI S Protein of unknown function (DUF3907)
PBLMHBDN_02239 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PBLMHBDN_02240 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PBLMHBDN_02242 1.7e-93 ypuF S Domain of unknown function (DUF309)
PBLMHBDN_02243 1e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PBLMHBDN_02244 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PBLMHBDN_02245 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PBLMHBDN_02246 2.2e-111 ribE 2.5.1.9 H Riboflavin synthase
PBLMHBDN_02247 6.8e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PBLMHBDN_02248 6.4e-49 ypuD
PBLMHBDN_02249 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PBLMHBDN_02250 1.2e-80 ccdC1 O Protein of unknown function (DUF1453)
PBLMHBDN_02251 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBLMHBDN_02252 1.9e-153 ypuA S Secreted protein
PBLMHBDN_02253 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PBLMHBDN_02254 3.2e-270 spoVAF EG Stage V sporulation protein AF
PBLMHBDN_02255 6.7e-110 spoVAEA S stage V sporulation protein
PBLMHBDN_02256 5e-57 spoVAEB S stage V sporulation protein
PBLMHBDN_02257 1.2e-188 spoVAD I Stage V sporulation protein AD
PBLMHBDN_02258 6e-79 spoVAC S stage V sporulation protein AC
PBLMHBDN_02259 5.1e-60 spoVAB S Stage V sporulation protein AB
PBLMHBDN_02260 1.8e-110 spoVAA S Stage V sporulation protein AA
PBLMHBDN_02261 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBLMHBDN_02262 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PBLMHBDN_02263 1.1e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
PBLMHBDN_02264 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
PBLMHBDN_02265 9.3e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PBLMHBDN_02266 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PBLMHBDN_02267 2.8e-165 xerD L recombinase XerD
PBLMHBDN_02268 3.7e-37 S Protein of unknown function (DUF4227)
PBLMHBDN_02269 1.9e-80 fur P Belongs to the Fur family
PBLMHBDN_02270 1.2e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PBLMHBDN_02272 8.6e-34 yqkK
PBLMHBDN_02273 5.7e-22
PBLMHBDN_02274 3.8e-243 mleA 1.1.1.38 C malic enzyme
PBLMHBDN_02275 1.6e-239 mleN C Na H antiporter
PBLMHBDN_02276 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
PBLMHBDN_02277 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
PBLMHBDN_02278 1e-57 ansR K Transcriptional regulator
PBLMHBDN_02279 4e-220 yqxK 3.6.4.12 L DNA helicase
PBLMHBDN_02280 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
PBLMHBDN_02282 2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
PBLMHBDN_02284 2e-174 yqkD S COG1073 Hydrolases of the alpha beta superfamily
PBLMHBDN_02285 3.2e-39 yqkC S Protein of unknown function (DUF2552)
PBLMHBDN_02286 7.7e-61 yqkB S Belongs to the HesB IscA family
PBLMHBDN_02287 7.6e-172 yqkA K GrpB protein
PBLMHBDN_02288 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
PBLMHBDN_02289 8.7e-89 yqjY K acetyltransferase
PBLMHBDN_02290 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PBLMHBDN_02291 1.4e-56 S YolD-like protein
PBLMHBDN_02293 6e-186 yueF S transporter activity
PBLMHBDN_02295 2.5e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PBLMHBDN_02296 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
PBLMHBDN_02297 5.7e-250 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
PBLMHBDN_02298 5.5e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
PBLMHBDN_02299 6.8e-173 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
PBLMHBDN_02300 6.9e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PBLMHBDN_02301 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
PBLMHBDN_02302 6.3e-238 pksG 2.3.3.10 I synthase
PBLMHBDN_02303 3.1e-220 eryK 1.14.13.154 C Cytochrome P450
PBLMHBDN_02304 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PBLMHBDN_02305 0.0 Q Polyketide synthase of type I
PBLMHBDN_02306 0.0 pfaA Q Polyketide synthase of type I
PBLMHBDN_02307 0.0 pksJ Q Polyketide synthase of type I
PBLMHBDN_02308 0.0 Q Polyketide synthase of type I
PBLMHBDN_02309 0.0 1.1.1.320 Q Polyketide synthase of type I
PBLMHBDN_02310 0.0 pksJ Q Polyketide synthase of type I
PBLMHBDN_02311 1.1e-127 IQ reductase
PBLMHBDN_02312 1e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PBLMHBDN_02315 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PBLMHBDN_02316 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
PBLMHBDN_02317 1.1e-161 K LysR substrate binding domain
PBLMHBDN_02318 5.5e-50 S GlpM protein
PBLMHBDN_02319 1.3e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PBLMHBDN_02320 1.8e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PBLMHBDN_02321 6.1e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PBLMHBDN_02322 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PBLMHBDN_02323 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PBLMHBDN_02324 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PBLMHBDN_02325 2.4e-25 yqzJ
PBLMHBDN_02326 1.7e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PBLMHBDN_02327 1.8e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
PBLMHBDN_02328 1.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PBLMHBDN_02329 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
PBLMHBDN_02331 3.1e-95 yqjB S protein conserved in bacteria
PBLMHBDN_02332 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
PBLMHBDN_02333 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PBLMHBDN_02334 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
PBLMHBDN_02335 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
PBLMHBDN_02336 1e-75 yqiW S Belongs to the UPF0403 family
PBLMHBDN_02337 1.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PBLMHBDN_02338 4.6e-201 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PBLMHBDN_02339 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PBLMHBDN_02340 9.5e-162 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PBLMHBDN_02341 1.3e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PBLMHBDN_02342 1.6e-205 buk 2.7.2.7 C Belongs to the acetokinase family
PBLMHBDN_02343 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
PBLMHBDN_02344 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
PBLMHBDN_02345 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
PBLMHBDN_02346 3.2e-34 yqzF S Protein of unknown function (DUF2627)
PBLMHBDN_02347 9e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PBLMHBDN_02348 1.2e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
PBLMHBDN_02349 1.9e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
PBLMHBDN_02350 3e-204 mmgC I acyl-CoA dehydrogenase
PBLMHBDN_02351 2.2e-154 hbdA 1.1.1.157 I Dehydrogenase
PBLMHBDN_02352 2.4e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
PBLMHBDN_02353 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PBLMHBDN_02354 8.8e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
PBLMHBDN_02355 1.2e-16
PBLMHBDN_02356 1.5e-101 ytaF P Probably functions as a manganese efflux pump
PBLMHBDN_02357 5.8e-112 K Protein of unknown function (DUF1232)
PBLMHBDN_02359 2.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PBLMHBDN_02362 1.2e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PBLMHBDN_02363 7.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PBLMHBDN_02364 6.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
PBLMHBDN_02365 3e-304 recN L May be involved in recombinational repair of damaged DNA
PBLMHBDN_02366 3.9e-78 argR K Regulates arginine biosynthesis genes
PBLMHBDN_02367 4.3e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
PBLMHBDN_02368 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PBLMHBDN_02369 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PBLMHBDN_02370 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PBLMHBDN_02371 1.3e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PBLMHBDN_02372 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PBLMHBDN_02373 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PBLMHBDN_02374 8.1e-67 yqhY S protein conserved in bacteria
PBLMHBDN_02375 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PBLMHBDN_02376 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PBLMHBDN_02377 2.5e-62 spoIIIAH S SpoIIIAH-like protein
PBLMHBDN_02378 1.1e-116 spoIIIAG S stage III sporulation protein AG
PBLMHBDN_02379 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
PBLMHBDN_02380 6.3e-200 spoIIIAE S stage III sporulation protein AE
PBLMHBDN_02381 2.5e-41 spoIIIAD S Stage III sporulation protein AD
PBLMHBDN_02382 7.6e-29 spoIIIAC S stage III sporulation protein AC
PBLMHBDN_02383 1.6e-83 spoIIIAB S Stage III sporulation protein
PBLMHBDN_02384 1.6e-171 spoIIIAA S stage III sporulation protein AA
PBLMHBDN_02385 1.8e-36 yqhV S Protein of unknown function (DUF2619)
PBLMHBDN_02386 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PBLMHBDN_02387 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
PBLMHBDN_02388 7e-87 yqhR S Conserved membrane protein YqhR
PBLMHBDN_02389 8e-174 yqhQ S Protein of unknown function (DUF1385)
PBLMHBDN_02390 5.8e-62 yqhP
PBLMHBDN_02391 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
PBLMHBDN_02392 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PBLMHBDN_02393 1.3e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PBLMHBDN_02394 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
PBLMHBDN_02395 4.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PBLMHBDN_02396 2.3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PBLMHBDN_02397 3.3e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
PBLMHBDN_02398 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PBLMHBDN_02399 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
PBLMHBDN_02400 5.2e-23 sinI S Anti-repressor SinI
PBLMHBDN_02401 7.8e-55 sinR K transcriptional
PBLMHBDN_02402 1.6e-140 tasA S Cell division protein FtsN
PBLMHBDN_02403 4.6e-71 sipW 3.4.21.89 U Signal peptidase
PBLMHBDN_02404 3.6e-120 yqxM
PBLMHBDN_02405 1.1e-53 yqzG S Protein of unknown function (DUF3889)
PBLMHBDN_02406 2.3e-26 yqzE S YqzE-like protein
PBLMHBDN_02407 2.1e-61 S ComG operon protein 7
PBLMHBDN_02408 1.6e-64 comGF U Putative Competence protein ComGF
PBLMHBDN_02409 2.6e-20 comGE
PBLMHBDN_02410 4.5e-71 gspH NU Tfp pilus assembly protein FimT
PBLMHBDN_02411 8.9e-50 comGC U Required for transformation and DNA binding
PBLMHBDN_02412 4.6e-183 comGB NU COG1459 Type II secretory pathway, component PulF
PBLMHBDN_02413 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PBLMHBDN_02414 1.2e-185 corA P Mg2 transporter protein
PBLMHBDN_02415 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PBLMHBDN_02416 9.4e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PBLMHBDN_02418 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
PBLMHBDN_02419 3.1e-37 yqgY S Protein of unknown function (DUF2626)
PBLMHBDN_02420 3.6e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PBLMHBDN_02421 5.4e-20 yqgW S Protein of unknown function (DUF2759)
PBLMHBDN_02422 1.7e-48 yqgV S Thiamine-binding protein
PBLMHBDN_02423 7.3e-197 yqgU
PBLMHBDN_02424 3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
PBLMHBDN_02425 7.5e-180 glcK 2.7.1.2 G Glucokinase
PBLMHBDN_02426 6.5e-28 yqgQ S Protein conserved in bacteria
PBLMHBDN_02427 9.2e-232 nhaC C Na H antiporter
PBLMHBDN_02428 4e-07 yqgO
PBLMHBDN_02429 4.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PBLMHBDN_02430 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PBLMHBDN_02431 1.2e-50 yqzD
PBLMHBDN_02432 1.1e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PBLMHBDN_02433 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PBLMHBDN_02434 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PBLMHBDN_02435 2.9e-154 pstA P Phosphate transport system permease
PBLMHBDN_02436 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
PBLMHBDN_02437 7.6e-158 pstS P Phosphate
PBLMHBDN_02438 0.0 pbpA 3.4.16.4 M penicillin-binding protein
PBLMHBDN_02439 3.4e-228 yqgE EGP Major facilitator superfamily
PBLMHBDN_02440 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
PBLMHBDN_02441 2.9e-71 yqgC S protein conserved in bacteria
PBLMHBDN_02442 4.3e-130 yqgB S Protein of unknown function (DUF1189)
PBLMHBDN_02443 3.4e-46 yqfZ M LysM domain
PBLMHBDN_02444 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PBLMHBDN_02445 2.3e-52 yqfX S membrane
PBLMHBDN_02446 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
PBLMHBDN_02447 2.9e-72 zur P Belongs to the Fur family
PBLMHBDN_02448 5.3e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
PBLMHBDN_02449 9.3e-37 yqfT S Protein of unknown function (DUF2624)
PBLMHBDN_02450 4.8e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PBLMHBDN_02451 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PBLMHBDN_02452 3.7e-43 yqfQ S YqfQ-like protein
PBLMHBDN_02453 6.5e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PBLMHBDN_02454 4.8e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PBLMHBDN_02455 3.8e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
PBLMHBDN_02456 2.4e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
PBLMHBDN_02457 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PBLMHBDN_02458 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PBLMHBDN_02459 6.1e-88 yaiI S Belongs to the UPF0178 family
PBLMHBDN_02460 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PBLMHBDN_02461 4.5e-112 ccpN K CBS domain
PBLMHBDN_02462 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PBLMHBDN_02463 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PBLMHBDN_02464 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
PBLMHBDN_02465 1.8e-16 S YqzL-like protein
PBLMHBDN_02466 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PBLMHBDN_02467 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PBLMHBDN_02468 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PBLMHBDN_02469 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PBLMHBDN_02470 0.0 yqfF S membrane-associated HD superfamily hydrolase
PBLMHBDN_02471 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
PBLMHBDN_02472 5.7e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
PBLMHBDN_02473 9.3e-46 yqfC S sporulation protein YqfC
PBLMHBDN_02474 1.9e-42 yqfB
PBLMHBDN_02475 3.8e-118 yqfA S UPF0365 protein
PBLMHBDN_02476 5.7e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
PBLMHBDN_02477 8e-68 yqeY S Yqey-like protein
PBLMHBDN_02478 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PBLMHBDN_02479 1.1e-154 yqeW P COG1283 Na phosphate symporter
PBLMHBDN_02480 1.3e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
PBLMHBDN_02481 7.4e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PBLMHBDN_02482 6.6e-173 prmA J Methylates ribosomal protein L11
PBLMHBDN_02483 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PBLMHBDN_02484 0.0 dnaK O Heat shock 70 kDa protein
PBLMHBDN_02485 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PBLMHBDN_02486 2.3e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PBLMHBDN_02487 2.2e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
PBLMHBDN_02488 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PBLMHBDN_02489 2.5e-53 yqxA S Protein of unknown function (DUF3679)
PBLMHBDN_02490 3.9e-218 spoIIP M stage II sporulation protein P
PBLMHBDN_02491 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PBLMHBDN_02492 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
PBLMHBDN_02493 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
PBLMHBDN_02494 0.0 comEC S Competence protein ComEC
PBLMHBDN_02495 8e-105 comEB 3.5.4.12 F ComE operon protein 2
PBLMHBDN_02496 6.2e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PBLMHBDN_02497 6.5e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PBLMHBDN_02498 1.2e-137 yqeM Q Methyltransferase
PBLMHBDN_02499 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PBLMHBDN_02500 2.2e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PBLMHBDN_02501 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PBLMHBDN_02502 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
PBLMHBDN_02503 1.2e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PBLMHBDN_02504 2.2e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PBLMHBDN_02505 7.6e-94 yqeG S hydrolase of the HAD superfamily
PBLMHBDN_02507 2.5e-138 yqeF E GDSL-like Lipase/Acylhydrolase
PBLMHBDN_02508 2.9e-139 3.5.1.104 G Polysaccharide deacetylase
PBLMHBDN_02509 8e-106 yqeD S SNARE associated Golgi protein
PBLMHBDN_02510 1.1e-199 EGP Major facilitator Superfamily
PBLMHBDN_02511 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBLMHBDN_02512 3.2e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
PBLMHBDN_02513 3.6e-91 K Transcriptional regulator PadR-like family
PBLMHBDN_02514 2.6e-147 ydeE K AraC family transcriptional regulator
PBLMHBDN_02516 4.4e-97 adk 2.7.4.3 F adenylate kinase activity
PBLMHBDN_02517 1.1e-21 yyaR K acetyltransferase
PBLMHBDN_02518 4e-219 tetL EGP Major facilitator Superfamily
PBLMHBDN_02519 2.1e-80 yyaR K Acetyltransferase (GNAT) domain
PBLMHBDN_02520 1.5e-91 yrdA S DinB family
PBLMHBDN_02521 9.5e-144 S hydrolase
PBLMHBDN_02522 2.8e-143 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
PBLMHBDN_02523 5.9e-129 glvR K Helix-turn-helix domain, rpiR family
PBLMHBDN_02524 2e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
PBLMHBDN_02525 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
PBLMHBDN_02526 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
PBLMHBDN_02527 2.1e-179 romA S Beta-lactamase superfamily domain
PBLMHBDN_02528 8.4e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PBLMHBDN_02529 4.1e-164 yybE K Transcriptional regulator
PBLMHBDN_02530 3.2e-212 ynfM EGP Major facilitator Superfamily
PBLMHBDN_02531 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
PBLMHBDN_02532 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
PBLMHBDN_02533 7.1e-79 yrhH Q methyltransferase
PBLMHBDN_02535 8e-143 focA P Formate nitrite
PBLMHBDN_02536 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
PBLMHBDN_02537 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
PBLMHBDN_02538 7e-81 yrhD S Protein of unknown function (DUF1641)
PBLMHBDN_02539 5.1e-34 yrhC S YrhC-like protein
PBLMHBDN_02540 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PBLMHBDN_02541 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
PBLMHBDN_02542 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PBLMHBDN_02543 2.3e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
PBLMHBDN_02544 4.1e-27 yrzA S Protein of unknown function (DUF2536)
PBLMHBDN_02545 8.1e-70 yrrS S Protein of unknown function (DUF1510)
PBLMHBDN_02546 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
PBLMHBDN_02547 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PBLMHBDN_02548 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
PBLMHBDN_02549 6.1e-246 yegQ O COG0826 Collagenase and related proteases
PBLMHBDN_02550 2.9e-173 yegQ O Peptidase U32
PBLMHBDN_02551 2.3e-116 yrrM 2.1.1.104 S O-methyltransferase
PBLMHBDN_02552 2e-189 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PBLMHBDN_02553 7.1e-46 yrzB S Belongs to the UPF0473 family
PBLMHBDN_02554 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PBLMHBDN_02555 8.5e-41 yrzL S Belongs to the UPF0297 family
PBLMHBDN_02556 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PBLMHBDN_02557 4.6e-162 yrrI S AI-2E family transporter
PBLMHBDN_02558 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PBLMHBDN_02559 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
PBLMHBDN_02560 6.1e-109 gluC P ABC transporter
PBLMHBDN_02561 2.9e-106 glnP P ABC transporter
PBLMHBDN_02562 2.1e-08 S Protein of unknown function (DUF3918)
PBLMHBDN_02563 2.9e-30 yrzR
PBLMHBDN_02564 3.4e-82 yrrD S protein conserved in bacteria
PBLMHBDN_02565 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PBLMHBDN_02566 1.7e-18 S COG0457 FOG TPR repeat
PBLMHBDN_02567 3.2e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PBLMHBDN_02568 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
PBLMHBDN_02569 7.8e-64 cymR K Transcriptional regulator
PBLMHBDN_02570 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PBLMHBDN_02571 8.2e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PBLMHBDN_02572 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PBLMHBDN_02573 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
PBLMHBDN_02576 1.6e-272 lytH 3.5.1.28 M COG3103 SH3 domain protein
PBLMHBDN_02577 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PBLMHBDN_02578 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PBLMHBDN_02579 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PBLMHBDN_02580 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PBLMHBDN_02581 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
PBLMHBDN_02582 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
PBLMHBDN_02583 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PBLMHBDN_02584 8.5e-50 yrzD S Post-transcriptional regulator
PBLMHBDN_02585 4.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PBLMHBDN_02586 9.5e-110 yrbG S membrane
PBLMHBDN_02587 2.4e-60 yrzE S Protein of unknown function (DUF3792)
PBLMHBDN_02588 2.5e-37 yajC U Preprotein translocase subunit YajC
PBLMHBDN_02589 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PBLMHBDN_02590 7e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PBLMHBDN_02591 1.6e-20 yrzS S Protein of unknown function (DUF2905)
PBLMHBDN_02592 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PBLMHBDN_02593 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PBLMHBDN_02594 3.7e-93 bofC S BofC C-terminal domain
PBLMHBDN_02596 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PBLMHBDN_02597 2.6e-113 safA M spore coat assembly protein SafA
PBLMHBDN_02598 2.7e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PBLMHBDN_02599 5.5e-150 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
PBLMHBDN_02600 3.3e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
PBLMHBDN_02601 7.3e-222 nifS 2.8.1.7 E Cysteine desulfurase
PBLMHBDN_02602 1.3e-93 niaR S small molecule binding protein (contains 3H domain)
PBLMHBDN_02603 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
PBLMHBDN_02604 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
PBLMHBDN_02605 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PBLMHBDN_02606 1.8e-104 spo0B T Sporulation initiation phospho-transferase B, C-terminal
PBLMHBDN_02607 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PBLMHBDN_02608 3.2e-56 ysxB J ribosomal protein
PBLMHBDN_02609 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
PBLMHBDN_02610 1.2e-160 spoIVFB S Stage IV sporulation protein
PBLMHBDN_02611 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
PBLMHBDN_02612 2.3e-142 minD D Belongs to the ParA family
PBLMHBDN_02613 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PBLMHBDN_02614 5.4e-84 mreD M shape-determining protein
PBLMHBDN_02615 3.6e-157 mreC M Involved in formation and maintenance of cell shape
PBLMHBDN_02616 4e-184 mreB D Rod shape-determining protein MreB
PBLMHBDN_02617 5.3e-127 radC E Belongs to the UPF0758 family
PBLMHBDN_02618 9.5e-98 maf D septum formation protein Maf
PBLMHBDN_02619 4.8e-137 spoIIB S Sporulation related domain
PBLMHBDN_02620 1.1e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PBLMHBDN_02621 1.8e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PBLMHBDN_02622 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PBLMHBDN_02623 2.1e-25
PBLMHBDN_02624 3.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PBLMHBDN_02625 1.7e-223 spoVID M stage VI sporulation protein D
PBLMHBDN_02626 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
PBLMHBDN_02627 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
PBLMHBDN_02628 1.6e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PBLMHBDN_02629 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PBLMHBDN_02630 6.8e-145 hemX O cytochrome C
PBLMHBDN_02631 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PBLMHBDN_02632 3.8e-87 ysxD
PBLMHBDN_02633 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
PBLMHBDN_02634 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PBLMHBDN_02635 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
PBLMHBDN_02636 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PBLMHBDN_02637 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PBLMHBDN_02638 1e-187 ysoA H Tetratricopeptide repeat
PBLMHBDN_02639 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PBLMHBDN_02640 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PBLMHBDN_02641 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PBLMHBDN_02642 6.7e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PBLMHBDN_02643 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PBLMHBDN_02644 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
PBLMHBDN_02645 0.0 ilvB 2.2.1.6 E Acetolactate synthase
PBLMHBDN_02648 1.4e-45 L COG2963 Transposase and inactivated derivatives
PBLMHBDN_02649 8.1e-118 L Molecular Function DNA binding, Biological Process DNA recombination
PBLMHBDN_02650 8.3e-13 pinR3 L Resolvase, N terminal domain
PBLMHBDN_02651 9.8e-54 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PBLMHBDN_02652 1.5e-248 hsdM 2.1.1.72 L type I restriction-modification system
PBLMHBDN_02653 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
PBLMHBDN_02657 3.2e-89 ysnB S Phosphoesterase
PBLMHBDN_02658 2.7e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PBLMHBDN_02659 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PBLMHBDN_02660 5.3e-198 gerM S COG5401 Spore germination protein
PBLMHBDN_02661 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PBLMHBDN_02662 2.1e-73 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
PBLMHBDN_02663 2e-30 gerE K Transcriptional regulator
PBLMHBDN_02664 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
PBLMHBDN_02665 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
PBLMHBDN_02666 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
PBLMHBDN_02667 4.8e-108 sdhC C succinate dehydrogenase
PBLMHBDN_02668 2e-79 yslB S Protein of unknown function (DUF2507)
PBLMHBDN_02669 9.2e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
PBLMHBDN_02670 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PBLMHBDN_02671 2.5e-52 trxA O Belongs to the thioredoxin family
PBLMHBDN_02672 1.6e-298 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
PBLMHBDN_02673 1.6e-177 etfA C Electron transfer flavoprotein
PBLMHBDN_02674 1.1e-136 etfB C Electron transfer flavoprotein
PBLMHBDN_02675 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
PBLMHBDN_02676 2.7e-103 fadR K Transcriptional regulator
PBLMHBDN_02677 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PBLMHBDN_02678 9.4e-90 ywbB S Protein of unknown function (DUF2711)
PBLMHBDN_02679 4.7e-67 yshE S membrane
PBLMHBDN_02680 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PBLMHBDN_02681 0.0 polX L COG1796 DNA polymerase IV (family X)
PBLMHBDN_02682 3.1e-82 cvpA S membrane protein, required for colicin V production
PBLMHBDN_02683 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PBLMHBDN_02684 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PBLMHBDN_02685 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PBLMHBDN_02686 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PBLMHBDN_02687 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBLMHBDN_02688 2e-32 sspI S Belongs to the SspI family
PBLMHBDN_02689 2.7e-202 ysfB KT regulator
PBLMHBDN_02690 4.5e-258 glcD 1.1.3.15 C FAD binding domain
PBLMHBDN_02691 6.4e-254 glcF C Glycolate oxidase
PBLMHBDN_02692 0.0 cstA T Carbon starvation protein
PBLMHBDN_02693 1.6e-298 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
PBLMHBDN_02694 9.9e-144 araQ G transport system permease
PBLMHBDN_02695 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
PBLMHBDN_02696 2.9e-251 araN G carbohydrate transport
PBLMHBDN_02697 6.8e-223 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PBLMHBDN_02698 4.3e-139 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
PBLMHBDN_02699 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PBLMHBDN_02700 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
PBLMHBDN_02701 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PBLMHBDN_02702 1.5e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
PBLMHBDN_02703 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
PBLMHBDN_02704 1.9e-65 ysdB S Sigma-w pathway protein YsdB
PBLMHBDN_02705 2.6e-42 ysdA S Membrane
PBLMHBDN_02706 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PBLMHBDN_02707 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PBLMHBDN_02708 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PBLMHBDN_02709 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PBLMHBDN_02710 2.9e-38 lrgA S effector of murein hydrolase LrgA
PBLMHBDN_02711 1.2e-129 lytT T COG3279 Response regulator of the LytR AlgR family
PBLMHBDN_02712 0.0 lytS 2.7.13.3 T Histidine kinase
PBLMHBDN_02713 1.5e-149 ysaA S HAD-hyrolase-like
PBLMHBDN_02714 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PBLMHBDN_02715 6.7e-153 ytxC S YtxC-like family
PBLMHBDN_02716 2.1e-106 ytxB S SNARE associated Golgi protein
PBLMHBDN_02717 9.5e-172 dnaI L Primosomal protein DnaI
PBLMHBDN_02718 1.6e-250 dnaB L Membrane attachment protein
PBLMHBDN_02719 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PBLMHBDN_02720 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PBLMHBDN_02721 2.2e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PBLMHBDN_02722 2e-67 ytcD K Transcriptional regulator
PBLMHBDN_02723 1.4e-204 ytbD EGP Major facilitator Superfamily
PBLMHBDN_02724 7.6e-160 ytbE S reductase
PBLMHBDN_02725 1.7e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PBLMHBDN_02726 2.1e-106 ytaF P Probably functions as a manganese efflux pump
PBLMHBDN_02727 3.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PBLMHBDN_02728 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PBLMHBDN_02729 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
PBLMHBDN_02730 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PBLMHBDN_02731 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
PBLMHBDN_02732 1.2e-241 icd 1.1.1.42 C isocitrate
PBLMHBDN_02733 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
PBLMHBDN_02736 9.4e-198 S Aspartate phosphatase response regulator
PBLMHBDN_02737 9.3e-53
PBLMHBDN_02738 1.6e-46 yjdF S Protein of unknown function (DUF2992)
PBLMHBDN_02739 1.1e-72 yeaL S membrane
PBLMHBDN_02740 2.4e-193 ytvI S sporulation integral membrane protein YtvI
PBLMHBDN_02741 3.5e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
PBLMHBDN_02742 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PBLMHBDN_02743 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PBLMHBDN_02744 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PBLMHBDN_02745 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PBLMHBDN_02746 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
PBLMHBDN_02747 0.0 dnaE 2.7.7.7 L DNA polymerase
PBLMHBDN_02748 9.2e-56 ytrH S Sporulation protein YtrH
PBLMHBDN_02749 4.3e-86 ytrI
PBLMHBDN_02750 5.8e-23
PBLMHBDN_02751 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
PBLMHBDN_02752 1.5e-46 ytpI S YtpI-like protein
PBLMHBDN_02753 1.6e-236 ytoI K transcriptional regulator containing CBS domains
PBLMHBDN_02754 1.3e-128 ytkL S Belongs to the UPF0173 family
PBLMHBDN_02755 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PBLMHBDN_02757 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
PBLMHBDN_02758 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PBLMHBDN_02759 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PBLMHBDN_02760 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PBLMHBDN_02761 9.1e-181 ytxK 2.1.1.72 L DNA methylase
PBLMHBDN_02762 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PBLMHBDN_02763 1.6e-60 ytfJ S Sporulation protein YtfJ
PBLMHBDN_02764 1e-93 ytfI S Protein of unknown function (DUF2953)
PBLMHBDN_02765 4.5e-88 yteJ S RDD family
PBLMHBDN_02766 6.4e-182 sppA OU signal peptide peptidase SppA
PBLMHBDN_02767 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PBLMHBDN_02768 1.7e-309 ytcJ S amidohydrolase
PBLMHBDN_02769 2.7e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PBLMHBDN_02770 3.9e-31 sspB S spore protein
PBLMHBDN_02771 2.8e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBLMHBDN_02772 5.9e-208 iscS2 2.8.1.7 E Cysteine desulfurase
PBLMHBDN_02773 2.6e-239 braB E Component of the transport system for branched-chain amino acids
PBLMHBDN_02774 4.7e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PBLMHBDN_02775 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
PBLMHBDN_02776 7.7e-109 yttP K Transcriptional regulator
PBLMHBDN_02777 4.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
PBLMHBDN_02778 9.5e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
PBLMHBDN_02779 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PBLMHBDN_02780 2.3e-251 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
PBLMHBDN_02781 1.5e-100 yokH G SMI1 / KNR4 family
PBLMHBDN_02783 1.3e-42
PBLMHBDN_02786 6.3e-17 S Phage-like element PBSX protein XtrA
PBLMHBDN_02787 8.5e-14
PBLMHBDN_02788 1.8e-28 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PBLMHBDN_02789 1.2e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PBLMHBDN_02790 2.5e-09
PBLMHBDN_02791 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
PBLMHBDN_02793 3e-136 E GDSL-like Lipase/Acylhydrolase family
PBLMHBDN_02794 1.1e-148 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PBLMHBDN_02795 1.4e-147 K Transcriptional regulator
PBLMHBDN_02796 5.2e-125 azlC E AzlC protein
PBLMHBDN_02797 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
PBLMHBDN_02798 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PBLMHBDN_02799 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PBLMHBDN_02800 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PBLMHBDN_02801 6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
PBLMHBDN_02802 4e-228 acuC BQ histone deacetylase
PBLMHBDN_02803 3.1e-119 motS N Flagellar motor protein
PBLMHBDN_02804 6.6e-145 motA N flagellar motor
PBLMHBDN_02805 6.4e-182 ccpA K catabolite control protein A
PBLMHBDN_02806 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PBLMHBDN_02807 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
PBLMHBDN_02808 1.7e-16 ytxH S COG4980 Gas vesicle protein
PBLMHBDN_02809 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PBLMHBDN_02810 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PBLMHBDN_02811 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
PBLMHBDN_02812 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PBLMHBDN_02813 3.7e-148 ytpQ S Belongs to the UPF0354 family
PBLMHBDN_02814 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PBLMHBDN_02815 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
PBLMHBDN_02816 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PBLMHBDN_02817 1.7e-51 ytzB S small secreted protein
PBLMHBDN_02818 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
PBLMHBDN_02819 2.1e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
PBLMHBDN_02820 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PBLMHBDN_02821 3.5e-45 ytzH S YtzH-like protein
PBLMHBDN_02822 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
PBLMHBDN_02823 6.8e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PBLMHBDN_02824 1.2e-166 ytlQ
PBLMHBDN_02825 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PBLMHBDN_02826 3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PBLMHBDN_02827 1.8e-267 pepV 3.5.1.18 E Dipeptidase
PBLMHBDN_02828 1.3e-227 pbuO S permease
PBLMHBDN_02829 6e-216 ythQ U Bacterial ABC transporter protein EcsB
PBLMHBDN_02830 3.7e-128 ythP V ABC transporter
PBLMHBDN_02831 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
PBLMHBDN_02832 2.4e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PBLMHBDN_02833 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PBLMHBDN_02834 5.7e-236 ytfP S HI0933-like protein
PBLMHBDN_02835 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
PBLMHBDN_02836 9e-26 yteV S Sporulation protein Cse60
PBLMHBDN_02837 4.8e-185 msmR K Transcriptional regulator
PBLMHBDN_02838 4.9e-243 msmE G Bacterial extracellular solute-binding protein
PBLMHBDN_02839 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
PBLMHBDN_02840 5.3e-142 amyC P ABC transporter (permease)
PBLMHBDN_02841 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
PBLMHBDN_02842 5.6e-83 M Acetyltransferase (GNAT) domain
PBLMHBDN_02843 5.6e-52 ytwF P Sulfurtransferase
PBLMHBDN_02844 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PBLMHBDN_02845 1.2e-52 ytvB S Protein of unknown function (DUF4257)
PBLMHBDN_02846 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
PBLMHBDN_02847 1.8e-207 yttB EGP Major facilitator Superfamily
PBLMHBDN_02848 3.1e-122 ywaF S Integral membrane protein
PBLMHBDN_02849 0.0 bceB V ABC transporter (permease)
PBLMHBDN_02850 4.9e-134 bceA V ABC transporter, ATP-binding protein
PBLMHBDN_02851 2.4e-170 T PhoQ Sensor
PBLMHBDN_02852 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PBLMHBDN_02853 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
PBLMHBDN_02854 2.2e-125 ytrE V ABC transporter, ATP-binding protein
PBLMHBDN_02855 2.2e-150
PBLMHBDN_02856 2.7e-172 P ABC-2 family transporter protein
PBLMHBDN_02857 2.6e-164 S ABC-2 family transporter protein
PBLMHBDN_02858 4.2e-161 ytrB P abc transporter atp-binding protein
PBLMHBDN_02859 3.9e-66 ytrA K GntR family transcriptional regulator
PBLMHBDN_02861 7.4e-40 ytzC S Protein of unknown function (DUF2524)
PBLMHBDN_02862 2e-192 K helix_turn_helix, Arsenical Resistance Operon Repressor
PBLMHBDN_02863 5.3e-282 norB EGP COG0477 Permeases of the major facilitator superfamily
PBLMHBDN_02864 1.1e-189 yhcC S Fe-S oxidoreductase
PBLMHBDN_02865 2.5e-106 ytqB J Putative rRNA methylase
PBLMHBDN_02867 2.6e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
PBLMHBDN_02868 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
PBLMHBDN_02869 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
PBLMHBDN_02870 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PBLMHBDN_02871 1.1e-259 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
PBLMHBDN_02872 0.0 asnB 6.3.5.4 E Asparagine synthase
PBLMHBDN_02873 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PBLMHBDN_02874 7.7e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PBLMHBDN_02875 1.6e-38 ytmB S Protein of unknown function (DUF2584)
PBLMHBDN_02876 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PBLMHBDN_02877 2.6e-183 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PBLMHBDN_02878 3.2e-144 ytlC P ABC transporter
PBLMHBDN_02879 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PBLMHBDN_02880 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
PBLMHBDN_02881 5e-61 ytkC S Bacteriophage holin family
PBLMHBDN_02882 7.8e-76 dps P Belongs to the Dps family
PBLMHBDN_02884 5.7e-74 ytkA S YtkA-like
PBLMHBDN_02885 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PBLMHBDN_02886 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PBLMHBDN_02887 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
PBLMHBDN_02888 7.9e-41 rpmE2 J Ribosomal protein L31
PBLMHBDN_02889 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
PBLMHBDN_02890 2.4e-184 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
PBLMHBDN_02891 2e-23 S Domain of Unknown Function (DUF1540)
PBLMHBDN_02892 7.8e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PBLMHBDN_02893 4.1e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PBLMHBDN_02894 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PBLMHBDN_02895 7.9e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PBLMHBDN_02896 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PBLMHBDN_02897 5.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
PBLMHBDN_02898 1.5e-129 dksA T COG1734 DnaK suppressor protein
PBLMHBDN_02899 2.6e-77 tspO T membrane
PBLMHBDN_02908 7.8e-08
PBLMHBDN_02909 1.3e-09
PBLMHBDN_02916 1.6e-08
PBLMHBDN_02921 3.4e-39 S COG NOG14552 non supervised orthologous group
PBLMHBDN_02922 3.1e-96 thiT S Thiamine transporter protein (Thia_YuaJ)
PBLMHBDN_02923 1.7e-178 yuaG 3.4.21.72 S protein conserved in bacteria
PBLMHBDN_02924 7.3e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
PBLMHBDN_02925 2e-72 yuaE S DinB superfamily
PBLMHBDN_02926 2.5e-109 yuaD S MOSC domain
PBLMHBDN_02927 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
PBLMHBDN_02928 4e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
PBLMHBDN_02929 8.6e-96 yuaC K Belongs to the GbsR family
PBLMHBDN_02930 3e-93 yuaB
PBLMHBDN_02931 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
PBLMHBDN_02932 1.5e-144 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PBLMHBDN_02933 9.4e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PBLMHBDN_02934 1.4e-118 G Cupin
PBLMHBDN_02935 2.2e-51 yjcN
PBLMHBDN_02939 7.6e-131 S Aspartate phosphatase response regulator
PBLMHBDN_02941 1.5e-13
PBLMHBDN_02943 3.8e-17
PBLMHBDN_02945 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PBLMHBDN_02946 2.9e-194 yubA S transporter activity
PBLMHBDN_02947 1.4e-184 ygjR S Oxidoreductase
PBLMHBDN_02948 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
PBLMHBDN_02949 6.5e-234 mcpA NT chemotaxis protein
PBLMHBDN_02950 6e-224 mcpA NT chemotaxis protein
PBLMHBDN_02951 1.2e-235 mcpA NT chemotaxis protein
PBLMHBDN_02952 8.1e-221 mcpA NT chemotaxis protein
PBLMHBDN_02953 2.2e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
PBLMHBDN_02954 1.4e-40
PBLMHBDN_02955 1.1e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PBLMHBDN_02956 2e-73 yugU S Uncharacterised protein family UPF0047
PBLMHBDN_02957 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
PBLMHBDN_02958 6.6e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
PBLMHBDN_02959 8.3e-117 yugP S Zn-dependent protease
PBLMHBDN_02960 3.4e-18
PBLMHBDN_02961 6.7e-27 mstX S Membrane-integrating protein Mistic
PBLMHBDN_02962 2e-180 yugO P COG1226 Kef-type K transport systems
PBLMHBDN_02963 7e-71 yugN S YugN-like family
PBLMHBDN_02965 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
PBLMHBDN_02966 7.1e-40 S NADPH-dependent FMN reductase
PBLMHBDN_02967 1.2e-117 ycaC Q Isochorismatase family
PBLMHBDN_02968 1.4e-228 yugK C Dehydrogenase
PBLMHBDN_02969 8.4e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
PBLMHBDN_02970 1.8e-34 yuzA S Domain of unknown function (DUF378)
PBLMHBDN_02971 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
PBLMHBDN_02972 1.6e-208 yugH 2.6.1.1 E Aminotransferase
PBLMHBDN_02973 2e-83 alaR K Transcriptional regulator
PBLMHBDN_02974 5.5e-155 yugF I Hydrolase
PBLMHBDN_02975 1.4e-40 yugE S Domain of unknown function (DUF1871)
PBLMHBDN_02976 1.3e-223 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PBLMHBDN_02977 8.9e-229 T PhoQ Sensor
PBLMHBDN_02978 7.7e-67 kapB G Kinase associated protein B
PBLMHBDN_02979 4e-118 kapD L the KinA pathway to sporulation
PBLMHBDN_02980 4.5e-185 yuxJ EGP Major facilitator Superfamily
PBLMHBDN_02981 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
PBLMHBDN_02982 2.2e-72 yuxK S protein conserved in bacteria
PBLMHBDN_02983 9.3e-74 yufK S Family of unknown function (DUF5366)
PBLMHBDN_02984 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PBLMHBDN_02985 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
PBLMHBDN_02986 2.7e-194 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
PBLMHBDN_02987 1.6e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PBLMHBDN_02988 8.4e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
PBLMHBDN_02989 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
PBLMHBDN_02990 2.3e-12
PBLMHBDN_02991 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PBLMHBDN_02992 1e-67 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PBLMHBDN_02993 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PBLMHBDN_02994 2.1e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PBLMHBDN_02995 1.3e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PBLMHBDN_02996 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PBLMHBDN_02997 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
PBLMHBDN_02998 3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
PBLMHBDN_02999 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PBLMHBDN_03000 5.2e-184 comP 2.7.13.3 T Histidine kinase
PBLMHBDN_03001 4.6e-206 comP 2.7.13.3 T Histidine kinase
PBLMHBDN_03003 8.6e-148 comQ H Polyprenyl synthetase
PBLMHBDN_03005 1.2e-50 yuzC
PBLMHBDN_03006 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
PBLMHBDN_03007 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PBLMHBDN_03008 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
PBLMHBDN_03009 7.2e-68 yueI S Protein of unknown function (DUF1694)
PBLMHBDN_03010 2.8e-38 yueH S YueH-like protein
PBLMHBDN_03011 6.4e-34 yueG S Spore germination protein gerPA/gerPF
PBLMHBDN_03012 5.6e-187 yueF S transporter activity
PBLMHBDN_03013 1.6e-22 S Protein of unknown function (DUF2642)
PBLMHBDN_03014 8.3e-96 yueE S phosphohydrolase
PBLMHBDN_03015 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PBLMHBDN_03016 4.2e-228 yukF QT Transcriptional regulator
PBLMHBDN_03017 3.9e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
PBLMHBDN_03018 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
PBLMHBDN_03019 1.1e-33 mbtH S MbtH-like protein
PBLMHBDN_03020 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_03021 5.2e-170 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
PBLMHBDN_03022 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
PBLMHBDN_03023 8.6e-218 entC 5.4.4.2 HQ Isochorismate synthase
PBLMHBDN_03024 1.8e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PBLMHBDN_03025 1.4e-164 besA S Putative esterase
PBLMHBDN_03026 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
PBLMHBDN_03027 1.5e-101 bioY S Biotin biosynthesis protein
PBLMHBDN_03028 1.2e-207 yuiF S antiporter
PBLMHBDN_03029 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PBLMHBDN_03030 1.6e-77 yuiD S protein conserved in bacteria
PBLMHBDN_03031 2.7e-117 yuiC S protein conserved in bacteria
PBLMHBDN_03032 9.9e-28 yuiB S Putative membrane protein
PBLMHBDN_03033 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
PBLMHBDN_03034 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
PBLMHBDN_03036 1.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PBLMHBDN_03037 4.8e-29
PBLMHBDN_03038 1e-69 CP Membrane
PBLMHBDN_03039 1.5e-121 V ABC transporter
PBLMHBDN_03041 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
PBLMHBDN_03043 2.3e-26 K helix_turn_helix, mercury resistance
PBLMHBDN_03044 1.6e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
PBLMHBDN_03045 1.1e-62 erpA S Belongs to the HesB IscA family
PBLMHBDN_03046 1.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PBLMHBDN_03047 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PBLMHBDN_03048 2.4e-39 yuzB S Belongs to the UPF0349 family
PBLMHBDN_03049 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
PBLMHBDN_03050 1.1e-53 yuzD S protein conserved in bacteria
PBLMHBDN_03051 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
PBLMHBDN_03052 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
PBLMHBDN_03053 6.4e-168 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PBLMHBDN_03054 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PBLMHBDN_03055 2.1e-241 hom 1.1.1.3 E homoserine dehydrogenase
PBLMHBDN_03056 3e-195 yutH S Spore coat protein
PBLMHBDN_03057 3.3e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
PBLMHBDN_03058 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PBLMHBDN_03059 6.8e-72 yutE S Protein of unknown function DUF86
PBLMHBDN_03060 1.7e-47 yutD S protein conserved in bacteria
PBLMHBDN_03061 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PBLMHBDN_03062 6.6e-192 lytH M Peptidase, M23
PBLMHBDN_03063 3.3e-130 yunB S Sporulation protein YunB (Spo_YunB)
PBLMHBDN_03064 1.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PBLMHBDN_03065 1.1e-144 yunE S membrane transporter protein
PBLMHBDN_03066 1.5e-168 yunF S Protein of unknown function DUF72
PBLMHBDN_03067 2.4e-59 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
PBLMHBDN_03068 1e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
PBLMHBDN_03069 4.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
PBLMHBDN_03070 1.5e-21
PBLMHBDN_03072 4.1e-212 blt EGP Major facilitator Superfamily
PBLMHBDN_03073 3.7e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PBLMHBDN_03074 1.5e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PBLMHBDN_03075 2.8e-165 bsn L Ribonuclease
PBLMHBDN_03076 2.7e-205 msmX P Belongs to the ABC transporter superfamily
PBLMHBDN_03077 3.6e-134 yurK K UTRA
PBLMHBDN_03078 4.5e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
PBLMHBDN_03079 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
PBLMHBDN_03080 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
PBLMHBDN_03081 1.4e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
PBLMHBDN_03082 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PBLMHBDN_03083 5e-165 K helix_turn_helix, mercury resistance
PBLMHBDN_03085 7e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
PBLMHBDN_03086 3.1e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
PBLMHBDN_03087 1.8e-127 Q ubiE/COQ5 methyltransferase family
PBLMHBDN_03088 6.7e-22 yncE S Protein of unknown function (DUF2691)
PBLMHBDN_03089 2.2e-24 yncE S Protein of unknown function (DUF2691)
PBLMHBDN_03090 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
PBLMHBDN_03091 8.7e-270 sufB O FeS cluster assembly
PBLMHBDN_03092 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
PBLMHBDN_03093 1e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PBLMHBDN_03094 7.7e-244 sufD O assembly protein SufD
PBLMHBDN_03095 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PBLMHBDN_03096 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PBLMHBDN_03097 3e-145 metQ P Belongs to the NlpA lipoprotein family
PBLMHBDN_03098 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
PBLMHBDN_03099 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PBLMHBDN_03100 1.5e-56 yusD S SCP-2 sterol transfer family
PBLMHBDN_03101 1.6e-54 yusE CO Thioredoxin
PBLMHBDN_03102 4.9e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
PBLMHBDN_03103 3.7e-40 yusG S Protein of unknown function (DUF2553)
PBLMHBDN_03104 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PBLMHBDN_03105 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
PBLMHBDN_03106 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
PBLMHBDN_03107 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
PBLMHBDN_03108 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
PBLMHBDN_03109 1.4e-164 fadM E Proline dehydrogenase
PBLMHBDN_03110 5.7e-42
PBLMHBDN_03111 1.1e-53 yusN M Coat F domain
PBLMHBDN_03112 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
PBLMHBDN_03113 8.1e-288 yusP P Major facilitator superfamily
PBLMHBDN_03114 8.5e-154 ywbI2 K Transcriptional regulator
PBLMHBDN_03115 1.6e-137 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
PBLMHBDN_03116 2.4e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PBLMHBDN_03117 3.3e-39 yusU S Protein of unknown function (DUF2573)
PBLMHBDN_03118 3.1e-150 yusV 3.6.3.34 HP ABC transporter
PBLMHBDN_03119 2.1e-44 S YusW-like protein
PBLMHBDN_03120 0.0 pepF2 E COG1164 Oligoendopeptidase F
PBLMHBDN_03121 2.7e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PBLMHBDN_03122 4.7e-79 dps P Belongs to the Dps family
PBLMHBDN_03123 3.8e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PBLMHBDN_03124 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PBLMHBDN_03125 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
PBLMHBDN_03126 3.4e-24
PBLMHBDN_03127 2.9e-157 yuxN K Transcriptional regulator
PBLMHBDN_03128 8.7e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PBLMHBDN_03129 6.6e-24 S Protein of unknown function (DUF3970)
PBLMHBDN_03130 1.2e-258 gerAA EG Spore germination protein
PBLMHBDN_03131 3.6e-186 gerAB E Spore germination protein
PBLMHBDN_03132 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
PBLMHBDN_03133 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PBLMHBDN_03134 2.3e-193 vraS 2.7.13.3 T Histidine kinase
PBLMHBDN_03135 1.9e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
PBLMHBDN_03136 3.3e-126 liaG S Putative adhesin
PBLMHBDN_03137 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
PBLMHBDN_03138 9e-44 liaI S membrane
PBLMHBDN_03139 2.2e-227 yvqJ EGP Major facilitator Superfamily
PBLMHBDN_03140 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
PBLMHBDN_03141 1.2e-219 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
PBLMHBDN_03142 2.7e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBLMHBDN_03143 1.6e-166 yvrC P ABC transporter substrate-binding protein
PBLMHBDN_03144 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PBLMHBDN_03145 1.1e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
PBLMHBDN_03146 0.0 T PhoQ Sensor
PBLMHBDN_03147 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PBLMHBDN_03148 1.1e-36
PBLMHBDN_03149 9.9e-103 yvrI K RNA polymerase
PBLMHBDN_03150 6.1e-15 S YvrJ protein family
PBLMHBDN_03151 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
PBLMHBDN_03152 2.1e-65 yvrL S Regulatory protein YrvL
PBLMHBDN_03153 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
PBLMHBDN_03154 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBLMHBDN_03155 3.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBLMHBDN_03156 4e-178 fhuD P ABC transporter
PBLMHBDN_03157 1.1e-127 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PBLMHBDN_03158 7e-235 yvsH E Arginine ornithine antiporter
PBLMHBDN_03159 5.2e-13 S Small spore protein J (Spore_SspJ)
PBLMHBDN_03160 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
PBLMHBDN_03161 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PBLMHBDN_03162 3.8e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
PBLMHBDN_03163 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
PBLMHBDN_03164 3.5e-99 modB P COG4149 ABC-type molybdate transport system, permease component
PBLMHBDN_03165 8.6e-114 yfiK K Regulator
PBLMHBDN_03166 2.8e-178 T Histidine kinase
PBLMHBDN_03167 1.6e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
PBLMHBDN_03168 1.3e-191 yfiM V ABC-2 type transporter
PBLMHBDN_03169 6.8e-196 yfiN V COG0842 ABC-type multidrug transport system, permease component
PBLMHBDN_03170 1.5e-155 yvgN S reductase
PBLMHBDN_03171 6e-85 yvgO
PBLMHBDN_03172 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
PBLMHBDN_03173 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PBLMHBDN_03174 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PBLMHBDN_03175 0.0 helD 3.6.4.12 L DNA helicase
PBLMHBDN_03176 3.1e-99 yvgT S membrane
PBLMHBDN_03177 4.4e-141 S Metallo-peptidase family M12
PBLMHBDN_03178 1.7e-72 bdbC O Required for disulfide bond formation in some proteins
PBLMHBDN_03179 3.5e-99 bdbD O Thioredoxin
PBLMHBDN_03180 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PBLMHBDN_03181 0.0 copA 3.6.3.54 P P-type ATPase
PBLMHBDN_03182 2.6e-29 copZ P Heavy-metal-associated domain
PBLMHBDN_03183 1.4e-47 csoR S transcriptional
PBLMHBDN_03184 4.1e-192 yvaA 1.1.1.371 S Oxidoreductase
PBLMHBDN_03185 2.5e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PBLMHBDN_03186 2e-252 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBLMHBDN_03187 5.6e-46 ytnI O COG0695 Glutaredoxin and related proteins
PBLMHBDN_03188 2.4e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBLMHBDN_03189 8e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PBLMHBDN_03190 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
PBLMHBDN_03191 2.7e-121 tcyL P Binding-protein-dependent transport system inner membrane component
PBLMHBDN_03192 5.4e-147 tcyK M Bacterial periplasmic substrate-binding proteins
PBLMHBDN_03193 1e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
PBLMHBDN_03194 3e-101 ytmI K Acetyltransferase (GNAT) domain
PBLMHBDN_03195 4.7e-160 ytlI K LysR substrate binding domain
PBLMHBDN_03196 1.7e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PBLMHBDN_03197 7e-47 yrdF K ribonuclease inhibitor
PBLMHBDN_03198 7.9e-56
PBLMHBDN_03201 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PBLMHBDN_03202 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PBLMHBDN_03203 1.6e-142 est 3.1.1.1 S Carboxylesterase
PBLMHBDN_03204 4.8e-24 secG U Preprotein translocase subunit SecG
PBLMHBDN_03205 6e-35 yvzC K Transcriptional
PBLMHBDN_03206 1.8e-69 K transcriptional
PBLMHBDN_03207 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
PBLMHBDN_03208 8.8e-53 yodB K transcriptional
PBLMHBDN_03209 2.4e-259 T His Kinase A (phosphoacceptor) domain
PBLMHBDN_03210 1.4e-121 K Transcriptional regulatory protein, C terminal
PBLMHBDN_03211 4.7e-132 mutG S ABC-2 family transporter protein
PBLMHBDN_03212 6e-121 spaE S ABC-2 family transporter protein
PBLMHBDN_03213 1.2e-126 mutF V ABC transporter, ATP-binding protein
PBLMHBDN_03214 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
PBLMHBDN_03215 3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PBLMHBDN_03216 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
PBLMHBDN_03217 3.3e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PBLMHBDN_03218 4.3e-76 yvbF K Belongs to the GbsR family
PBLMHBDN_03219 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
PBLMHBDN_03220 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PBLMHBDN_03221 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
PBLMHBDN_03222 3.3e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PBLMHBDN_03223 3.5e-97 yvbF K Belongs to the GbsR family
PBLMHBDN_03224 9.8e-104 yvbG U UPF0056 membrane protein
PBLMHBDN_03225 1.1e-119 exoY M Membrane
PBLMHBDN_03226 0.0 tcaA S response to antibiotic
PBLMHBDN_03227 2.5e-80 yvbK 3.1.3.25 K acetyltransferase
PBLMHBDN_03230 5.8e-196 3.6.3.27 V Peptidase C39 family
PBLMHBDN_03231 2.6e-191 lcnDR2 V Lanthionine synthetase C-like protein
PBLMHBDN_03233 1.4e-211 lcnDR2 V Lanthionine synthetase C-like protein
PBLMHBDN_03235 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PBLMHBDN_03236 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
PBLMHBDN_03237 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PBLMHBDN_03238 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PBLMHBDN_03239 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PBLMHBDN_03240 2.6e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PBLMHBDN_03242 7.4e-253 araE EGP Major facilitator Superfamily
PBLMHBDN_03243 5.5e-203 araR K transcriptional
PBLMHBDN_03244 8.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBLMHBDN_03246 2.4e-156 yvbU K Transcriptional regulator
PBLMHBDN_03247 6.5e-157 yvbV EG EamA-like transporter family
PBLMHBDN_03248 3.8e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
PBLMHBDN_03249 1.6e-257
PBLMHBDN_03250 2.1e-182 purR7 5.1.1.1 K Transcriptional regulator
PBLMHBDN_03251 9.4e-113 yyaS S Membrane
PBLMHBDN_03252 7.4e-166 3.1.3.104 S hydrolases of the HAD superfamily
PBLMHBDN_03253 2e-152 ybbH_1 K RpiR family transcriptional regulator
PBLMHBDN_03254 2.7e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
PBLMHBDN_03255 3.3e-210 gntP EG COG2610 H gluconate symporter and related permeases
PBLMHBDN_03256 7.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PBLMHBDN_03257 1.1e-270 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PBLMHBDN_03258 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PBLMHBDN_03259 2.7e-219 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PBLMHBDN_03260 3e-120 yvfI K COG2186 Transcriptional regulators
PBLMHBDN_03261 1.4e-303 yvfH C L-lactate permease
PBLMHBDN_03262 1e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PBLMHBDN_03263 2.7e-32 yvfG S YvfG protein
PBLMHBDN_03264 3.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
PBLMHBDN_03265 6.9e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
PBLMHBDN_03266 8.4e-50 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
PBLMHBDN_03267 1.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PBLMHBDN_03268 2.4e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PBLMHBDN_03269 1.9e-192 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
PBLMHBDN_03270 1.2e-202 epsI GM pyruvyl transferase
PBLMHBDN_03271 4.1e-192 epsH GT2 S Glycosyltransferase like family 2
PBLMHBDN_03272 5e-204 epsG S EpsG family
PBLMHBDN_03273 2.3e-212 epsF GT4 M Glycosyl transferases group 1
PBLMHBDN_03274 1.5e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PBLMHBDN_03275 3.3e-219 epsD GT4 M Glycosyl transferase 4-like
PBLMHBDN_03276 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
PBLMHBDN_03277 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
PBLMHBDN_03278 3.5e-118 ywqC M biosynthesis protein
PBLMHBDN_03279 5.7e-77 slr K transcriptional
PBLMHBDN_03280 1.3e-281 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
PBLMHBDN_03282 9.8e-97 ywjB H RibD C-terminal domain
PBLMHBDN_03283 4.4e-112 yyaS S Membrane
PBLMHBDN_03284 3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PBLMHBDN_03285 1.6e-93 padC Q Phenolic acid decarboxylase
PBLMHBDN_03286 3.8e-15 S Protein of unknown function (DUF1433)
PBLMHBDN_03287 2.2e-17 S Protein of unknown function (DUF1433)
PBLMHBDN_03288 9.8e-18 S Protein of unknown function (DUF1433)
PBLMHBDN_03289 7.8e-266 I Pfam Lipase (class 3)
PBLMHBDN_03290 2.6e-33
PBLMHBDN_03292 4.5e-293 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
PBLMHBDN_03293 1.6e-219 rafB P LacY proton/sugar symporter
PBLMHBDN_03294 1.1e-181 scrR K transcriptional
PBLMHBDN_03295 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PBLMHBDN_03296 3.3e-163 yraN K Transcriptional regulator
PBLMHBDN_03297 1.4e-209 yraM S PrpF protein
PBLMHBDN_03298 1.6e-247 EGP Sugar (and other) transporter
PBLMHBDN_03299 2.8e-105 yvdD 3.2.2.10 S Belongs to the LOG family
PBLMHBDN_03300 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
PBLMHBDN_03301 5.6e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
PBLMHBDN_03302 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
PBLMHBDN_03303 5e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBLMHBDN_03304 4.6e-79 M Ribonuclease
PBLMHBDN_03305 1.4e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
PBLMHBDN_03306 1.8e-35 crh G Phosphocarrier protein Chr
PBLMHBDN_03307 4.1e-170 whiA K May be required for sporulation
PBLMHBDN_03308 3.8e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PBLMHBDN_03309 1.1e-166 rapZ S Displays ATPase and GTPase activities
PBLMHBDN_03310 1.3e-10 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PBLMHBDN_03311 2.7e-23 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PBLMHBDN_03312 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PBLMHBDN_03313 1.3e-124 usp CBM50 M protein conserved in bacteria
PBLMHBDN_03314 5e-276 S COG0457 FOG TPR repeat
PBLMHBDN_03315 5.2e-190 sasA T Histidine kinase
PBLMHBDN_03316 9.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PBLMHBDN_03317 1.2e-46
PBLMHBDN_03318 0.0 msbA2 3.6.3.44 V ABC transporter
PBLMHBDN_03319 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
PBLMHBDN_03320 1.7e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PBLMHBDN_03321 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PBLMHBDN_03322 4.7e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PBLMHBDN_03323 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PBLMHBDN_03324 1.4e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PBLMHBDN_03325 1.1e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PBLMHBDN_03326 1e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PBLMHBDN_03327 3.5e-137 yvpB NU protein conserved in bacteria
PBLMHBDN_03328 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
PBLMHBDN_03329 7e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PBLMHBDN_03330 1.5e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PBLMHBDN_03331 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PBLMHBDN_03332 3e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PBLMHBDN_03333 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PBLMHBDN_03334 2.3e-133 yvoA K transcriptional
PBLMHBDN_03335 4.4e-103 yxaF K Transcriptional regulator
PBLMHBDN_03336 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
PBLMHBDN_03337 1.5e-40 yvlD S Membrane
PBLMHBDN_03338 9.6e-26 pspB KT PspC domain
PBLMHBDN_03339 1.2e-165 yvlB S Putative adhesin
PBLMHBDN_03340 6.1e-49 yvlA
PBLMHBDN_03341 2.2e-32 yvkN
PBLMHBDN_03342 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PBLMHBDN_03343 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PBLMHBDN_03344 7.6e-33 csbA S protein conserved in bacteria
PBLMHBDN_03345 0.0 yvkC 2.7.9.2 GT Phosphotransferase
PBLMHBDN_03346 1.7e-108 yvkB K Transcriptional regulator
PBLMHBDN_03347 1.9e-226 yvkA EGP Major facilitator Superfamily
PBLMHBDN_03349 2.1e-17 L Transposase, Mutator family
PBLMHBDN_03350 5.1e-27 L Transposase, Mutator family
PBLMHBDN_03351 1.3e-26 bacT Q Thioesterase domain
PBLMHBDN_03353 1.1e-174 S Psort location CytoplasmicMembrane, score
PBLMHBDN_03354 8.3e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PBLMHBDN_03355 1.5e-55 swrA S Swarming motility protein
PBLMHBDN_03356 1.1e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
PBLMHBDN_03357 8.6e-225 ywoF P Right handed beta helix region
PBLMHBDN_03358 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PBLMHBDN_03359 2.3e-122 ftsE D cell division ATP-binding protein FtsE
PBLMHBDN_03360 8.1e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
PBLMHBDN_03361 1.5e-147 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
PBLMHBDN_03362 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PBLMHBDN_03363 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PBLMHBDN_03364 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PBLMHBDN_03365 6.8e-68
PBLMHBDN_03366 5.9e-10 fliT S bacterial-type flagellum organization
PBLMHBDN_03367 3e-66 fliS N flagellar protein FliS
PBLMHBDN_03368 2e-243 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PBLMHBDN_03369 9.4e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PBLMHBDN_03370 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PBLMHBDN_03371 7.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PBLMHBDN_03372 1.4e-80 yviE
PBLMHBDN_03373 2.3e-162 flgL N Belongs to the bacterial flagellin family
PBLMHBDN_03374 1.4e-273 flgK N flagellar hook-associated protein
PBLMHBDN_03375 8.9e-81 flgN NOU FlgN protein
PBLMHBDN_03376 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
PBLMHBDN_03377 4.1e-74 yvyF S flagellar protein
PBLMHBDN_03378 6.5e-76 comFC S Phosphoribosyl transferase domain
PBLMHBDN_03379 1.7e-42 comFB S Late competence development protein ComFB
PBLMHBDN_03380 3.2e-256 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PBLMHBDN_03381 1.4e-158 degV S protein conserved in bacteria
PBLMHBDN_03382 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PBLMHBDN_03383 3.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PBLMHBDN_03384 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
PBLMHBDN_03385 1e-165 yvhJ K Transcriptional regulator
PBLMHBDN_03386 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PBLMHBDN_03387 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
PBLMHBDN_03388 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
PBLMHBDN_03389 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
PBLMHBDN_03390 5.7e-253 tuaE M Teichuronic acid biosynthesis protein
PBLMHBDN_03391 7.6e-247 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PBLMHBDN_03392 1.5e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
PBLMHBDN_03393 6.1e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PBLMHBDN_03394 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PBLMHBDN_03395 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PBLMHBDN_03396 0.0 lytB 3.5.1.28 D Stage II sporulation protein
PBLMHBDN_03397 2.3e-48
PBLMHBDN_03398 8.5e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PBLMHBDN_03399 2e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PBLMHBDN_03400 1.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PBLMHBDN_03401 1.9e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PBLMHBDN_03402 1.7e-151 tagG GM Transport permease protein
PBLMHBDN_03403 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PBLMHBDN_03404 6e-280 M Glycosyltransferase like family 2
PBLMHBDN_03405 4.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
PBLMHBDN_03406 2.9e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PBLMHBDN_03407 3.4e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PBLMHBDN_03408 4e-231 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PBLMHBDN_03409 5.9e-185 pmi 5.3.1.8 G mannose-6-phosphate isomerase
PBLMHBDN_03410 8.2e-263 gerBA EG Spore germination protein
PBLMHBDN_03411 4.3e-195 gerBB E Spore germination protein
PBLMHBDN_03412 6.3e-210 gerAC S Spore germination protein
PBLMHBDN_03413 6.8e-267 GT2,GT4 J Glycosyl transferase family 2
PBLMHBDN_03414 4.1e-248 ywtG EGP Major facilitator Superfamily
PBLMHBDN_03415 7.2e-178 ywtF K Transcriptional regulator
PBLMHBDN_03416 9.4e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
PBLMHBDN_03417 5.5e-34 yttA 2.7.13.3 S Pfam Transposase IS66
PBLMHBDN_03418 6.6e-237 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PBLMHBDN_03419 1.3e-20 ywtC
PBLMHBDN_03420 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
PBLMHBDN_03421 2.3e-70 pgsC S biosynthesis protein
PBLMHBDN_03422 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
PBLMHBDN_03423 1e-183 gerKA EG Spore germination protein
PBLMHBDN_03424 1.4e-190 gerKB E Spore germination protein
PBLMHBDN_03425 9.1e-201 gerKC S Spore germination B3/ GerAC like, C-terminal
PBLMHBDN_03426 4.2e-178 rbsR K transcriptional
PBLMHBDN_03427 1.2e-155 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PBLMHBDN_03428 3.4e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PBLMHBDN_03429 1.6e-277 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PBLMHBDN_03430 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
PBLMHBDN_03431 9.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
PBLMHBDN_03432 2e-89 batE T Sh3 type 3 domain protein
PBLMHBDN_03433 5.3e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
PBLMHBDN_03434 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
PBLMHBDN_03435 2.2e-307 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PBLMHBDN_03436 2.6e-166 alsR K LysR substrate binding domain
PBLMHBDN_03437 3.2e-237 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PBLMHBDN_03438 4.4e-126 ywrJ
PBLMHBDN_03439 6e-131 cotB
PBLMHBDN_03440 5.5e-211 cotH M Spore Coat
PBLMHBDN_03441 2e-09
PBLMHBDN_03442 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PBLMHBDN_03444 1.9e-297 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PBLMHBDN_03445 2.5e-83 ywrC K Transcriptional regulator
PBLMHBDN_03446 5e-102 ywrB P Chromate transporter
PBLMHBDN_03447 1.4e-87 ywrA P COG2059 Chromate transport protein ChrA
PBLMHBDN_03449 2.1e-94 ywqN S NAD(P)H-dependent
PBLMHBDN_03450 5.3e-156 K Transcriptional regulator
PBLMHBDN_03451 8.1e-73 ywqG S Domain of unknown function (DUF1963)
PBLMHBDN_03452 4.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PBLMHBDN_03453 1.9e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
PBLMHBDN_03454 9.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
PBLMHBDN_03455 8.3e-110 ywqC M biosynthesis protein
PBLMHBDN_03456 1.3e-14
PBLMHBDN_03457 1.6e-307 ywqB S SWIM zinc finger
PBLMHBDN_03458 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PBLMHBDN_03459 1.7e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
PBLMHBDN_03460 7.5e-138 glcR K DeoR C terminal sensor domain
PBLMHBDN_03461 3.7e-57 ssbB L Single-stranded DNA-binding protein
PBLMHBDN_03462 4e-62 ywpG
PBLMHBDN_03463 2.5e-68 ywpF S YwpF-like protein
PBLMHBDN_03464 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PBLMHBDN_03465 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PBLMHBDN_03466 5.2e-198 S aspartate phosphatase
PBLMHBDN_03467 2.4e-142 flhP N flagellar basal body
PBLMHBDN_03468 5.5e-128 flhO N flagellar basal body
PBLMHBDN_03469 2.7e-180 mbl D Rod shape-determining protein
PBLMHBDN_03470 1.8e-44 spoIIID K Stage III sporulation protein D
PBLMHBDN_03471 4.2e-71 ywoH K transcriptional
PBLMHBDN_03472 1.9e-212 ywoG EGP Major facilitator Superfamily
PBLMHBDN_03473 1.2e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
PBLMHBDN_03474 1.6e-244 ywoD EGP Major facilitator superfamily
PBLMHBDN_03475 4.8e-102 phzA Q Isochorismatase family
PBLMHBDN_03476 2.5e-228 amt P Ammonium transporter
PBLMHBDN_03477 2e-58 nrgB K Belongs to the P(II) protein family
PBLMHBDN_03478 3.9e-207 ftsW D Belongs to the SEDS family
PBLMHBDN_03479 1.2e-100 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
PBLMHBDN_03480 5.6e-71 ywnJ S VanZ like family
PBLMHBDN_03481 4.2e-121 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
PBLMHBDN_03482 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
PBLMHBDN_03483 1.2e-10 ywnC S Family of unknown function (DUF5362)
PBLMHBDN_03484 1.2e-68 ywnF S Family of unknown function (DUF5392)
PBLMHBDN_03485 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PBLMHBDN_03486 1.2e-51 ywnC S Family of unknown function (DUF5362)
PBLMHBDN_03487 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
PBLMHBDN_03488 6.1e-67 ywnA K Transcriptional regulator
PBLMHBDN_03489 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PBLMHBDN_03490 9.4e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PBLMHBDN_03491 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PBLMHBDN_03492 1.4e-10 csbD K CsbD-like
PBLMHBDN_03493 2.3e-81 ywmF S Peptidase M50
PBLMHBDN_03494 2.8e-93 S response regulator aspartate phosphatase
PBLMHBDN_03495 1.6e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PBLMHBDN_03496 4.2e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PBLMHBDN_03498 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
PBLMHBDN_03499 5.1e-114 ywmC S protein containing a von Willebrand factor type A (vWA) domain
PBLMHBDN_03500 1.2e-178 spoIID D Stage II sporulation protein D
PBLMHBDN_03501 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PBLMHBDN_03502 2.2e-134 ywmB S TATA-box binding
PBLMHBDN_03503 4.8e-32 ywzB S membrane
PBLMHBDN_03504 8.7e-89 ywmA
PBLMHBDN_03505 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PBLMHBDN_03506 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PBLMHBDN_03507 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PBLMHBDN_03508 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PBLMHBDN_03509 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PBLMHBDN_03510 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PBLMHBDN_03511 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PBLMHBDN_03512 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
PBLMHBDN_03513 2.1e-61 atpI S ATP synthase
PBLMHBDN_03514 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PBLMHBDN_03515 5.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PBLMHBDN_03516 1.7e-96 ywlG S Belongs to the UPF0340 family
PBLMHBDN_03517 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
PBLMHBDN_03518 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PBLMHBDN_03519 1.3e-83 mntP P Probably functions as a manganese efflux pump
PBLMHBDN_03520 1.5e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PBLMHBDN_03521 3.9e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
PBLMHBDN_03522 8.9e-119 spoIIR S stage II sporulation protein R
PBLMHBDN_03523 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
PBLMHBDN_03525 4.8e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PBLMHBDN_03526 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PBLMHBDN_03527 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PBLMHBDN_03528 2.2e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
PBLMHBDN_03529 6.8e-157 ywkB S Membrane transport protein
PBLMHBDN_03530 0.0 sfcA 1.1.1.38 C malic enzyme
PBLMHBDN_03531 1.7e-102 tdk 2.7.1.21 F thymidine kinase
PBLMHBDN_03532 1.1e-32 rpmE J Binds the 23S rRNA
PBLMHBDN_03533 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PBLMHBDN_03534 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
PBLMHBDN_03535 1.2e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PBLMHBDN_03536 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PBLMHBDN_03537 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
PBLMHBDN_03538 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
PBLMHBDN_03539 7.1e-92 ywjG S Domain of unknown function (DUF2529)
PBLMHBDN_03540 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PBLMHBDN_03541 3.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PBLMHBDN_03542 0.0 fadF C COG0247 Fe-S oxidoreductase
PBLMHBDN_03543 5.2e-215 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PBLMHBDN_03544 7.5e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
PBLMHBDN_03545 4.2e-43 ywjC
PBLMHBDN_03546 0.0 ywjA V ABC transporter
PBLMHBDN_03547 1.8e-295 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PBLMHBDN_03548 4e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PBLMHBDN_03549 7.2e-121 narI 1.7.5.1 C nitrate reductase, gamma
PBLMHBDN_03550 1.5e-92 narJ 1.7.5.1 C nitrate reductase
PBLMHBDN_03551 1.1e-294 narH 1.7.5.1 C Nitrate reductase, beta
PBLMHBDN_03552 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PBLMHBDN_03553 2e-85 arfM T cyclic nucleotide binding
PBLMHBDN_03554 2.8e-139 ywiC S YwiC-like protein
PBLMHBDN_03555 3.8e-128 fnr K helix_turn_helix, cAMP Regulatory protein
PBLMHBDN_03556 1.7e-210 narK P COG2223 Nitrate nitrite transporter
PBLMHBDN_03557 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PBLMHBDN_03558 2.9e-43 ywiB S protein conserved in bacteria
PBLMHBDN_03559 5.8e-78 S aspartate phosphatase
PBLMHBDN_03561 3.8e-57 speB 3.5.3.11 E Belongs to the arginase family
PBLMHBDN_03563 2.3e-25 norM_1 V drug transmembrane transporter activity
PBLMHBDN_03564 1.2e-37 C Nitroreductase family
PBLMHBDN_03565 1.6e-42 C coenzyme F420-1:gamma-L-glutamate ligase activity
PBLMHBDN_03567 8e-230 argS 6.1.1.19 J Arginyl-tRNA synthetase
PBLMHBDN_03568 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
PBLMHBDN_03569 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PBLMHBDN_03570 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PBLMHBDN_03571 1e-80
PBLMHBDN_03572 6.4e-93 ywhD S YwhD family
PBLMHBDN_03573 1.2e-117 ywhC S Peptidase family M50
PBLMHBDN_03574 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
PBLMHBDN_03575 4.9e-67 ywhA K Transcriptional regulator
PBLMHBDN_03576 9.6e-245 yhdG_1 E C-terminus of AA_permease
PBLMHBDN_03577 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
PBLMHBDN_03578 5.6e-255 ywfO S COG1078 HD superfamily phosphohydrolases
PBLMHBDN_03579 6.9e-36 ywzC S Belongs to the UPF0741 family
PBLMHBDN_03580 6.6e-110 rsfA_1
PBLMHBDN_03581 9.7e-52 padR K PadR family transcriptional regulator
PBLMHBDN_03582 2e-92 S membrane
PBLMHBDN_03583 6.1e-163 V ABC transporter, ATP-binding protein
PBLMHBDN_03584 4.2e-167 yhcI S ABC transporter (permease)
PBLMHBDN_03587 3.7e-176
PBLMHBDN_03589 5e-159 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PBLMHBDN_03590 2.2e-148 cysL K Transcriptional regulator
PBLMHBDN_03591 4e-157 MA20_14895 S Conserved hypothetical protein 698
PBLMHBDN_03592 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
PBLMHBDN_03593 1.1e-146 ywfI C May function as heme-dependent peroxidase
PBLMHBDN_03594 2.8e-140 IQ Enoyl-(Acyl carrier protein) reductase
PBLMHBDN_03595 1.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
PBLMHBDN_03596 2.3e-207 bacE EGP Major facilitator Superfamily
PBLMHBDN_03597 8.3e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
PBLMHBDN_03598 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PBLMHBDN_03599 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
PBLMHBDN_03600 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
PBLMHBDN_03601 1.7e-221 ywfA EGP Major facilitator Superfamily
PBLMHBDN_03602 6.4e-205 tcaB EGP Major facilitator Superfamily
PBLMHBDN_03603 1.2e-258 lysP E amino acid
PBLMHBDN_03604 0.0 rocB E arginine degradation protein
PBLMHBDN_03605 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
PBLMHBDN_03606 1.1e-245 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
PBLMHBDN_03607 4.1e-59
PBLMHBDN_03608 3e-86 spsL 5.1.3.13 M Spore Coat
PBLMHBDN_03609 4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PBLMHBDN_03610 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PBLMHBDN_03611 1.3e-136 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PBLMHBDN_03612 1.5e-178 spsG M Spore Coat
PBLMHBDN_03613 2.6e-132 spsF M Spore Coat
PBLMHBDN_03614 2.4e-214 spsE 2.5.1.56 M acid synthase
PBLMHBDN_03615 8.9e-156 spsD 2.3.1.210 K Spore Coat
PBLMHBDN_03616 5.8e-219 spsC E Belongs to the DegT DnrJ EryC1 family
PBLMHBDN_03617 9.1e-275 spsB M Capsule polysaccharide biosynthesis protein
PBLMHBDN_03618 3.8e-142 spsA M Spore Coat
PBLMHBDN_03619 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PBLMHBDN_03620 4.2e-46 ywdK S small membrane protein
PBLMHBDN_03621 5.4e-229 ywdJ F Xanthine uracil
PBLMHBDN_03622 4.7e-41 ywdI S Family of unknown function (DUF5327)
PBLMHBDN_03623 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PBLMHBDN_03624 1.8e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
PBLMHBDN_03626 1.3e-87 ywdD
PBLMHBDN_03627 6.3e-57 pex K Transcriptional regulator PadR-like family
PBLMHBDN_03628 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PBLMHBDN_03629 7.4e-20 ywdA
PBLMHBDN_03630 3.2e-283 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
PBLMHBDN_03631 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PBLMHBDN_03632 3.7e-151 sacT K transcriptional antiterminator
PBLMHBDN_03634 0.0 vpr O Belongs to the peptidase S8 family
PBLMHBDN_03635 1.1e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBLMHBDN_03636 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
PBLMHBDN_03637 1.6e-208 rodA D Belongs to the SEDS family
PBLMHBDN_03638 1.7e-76 ysnE K acetyltransferase
PBLMHBDN_03639 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
PBLMHBDN_03640 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
PBLMHBDN_03641 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
PBLMHBDN_03642 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PBLMHBDN_03643 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PBLMHBDN_03644 8.4e-27 ywzA S membrane
PBLMHBDN_03645 3.9e-295 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PBLMHBDN_03646 5.1e-61 gtcA S GtrA-like protein
PBLMHBDN_03647 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
PBLMHBDN_03649 7.3e-129 H Methionine biosynthesis protein MetW
PBLMHBDN_03650 1.2e-131 S Streptomycin biosynthesis protein StrF
PBLMHBDN_03651 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PBLMHBDN_03652 1.1e-242 ywbN P Dyp-type peroxidase family protein
PBLMHBDN_03653 3.3e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PBLMHBDN_03654 4.8e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PBLMHBDN_03655 8.2e-152 ywbI K Transcriptional regulator
PBLMHBDN_03656 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PBLMHBDN_03657 1.3e-109 ywbG M effector of murein hydrolase
PBLMHBDN_03658 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
PBLMHBDN_03659 2.5e-138 mta K transcriptional
PBLMHBDN_03660 1e-223 ywbD 2.1.1.191 J Methyltransferase
PBLMHBDN_03661 7.6e-67 ywbC 4.4.1.5 E glyoxalase
PBLMHBDN_03662 5.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PBLMHBDN_03663 1.5e-258 epr 3.4.21.62 O Belongs to the peptidase S8 family
PBLMHBDN_03664 4.1e-161 gspA M General stress
PBLMHBDN_03665 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
PBLMHBDN_03666 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
PBLMHBDN_03667 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
PBLMHBDN_03668 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_03669 4.8e-229 dltB M membrane protein involved in D-alanine export
PBLMHBDN_03670 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PBLMHBDN_03671 4.5e-227 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PBLMHBDN_03672 9.3e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PBLMHBDN_03673 4.6e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PBLMHBDN_03674 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
PBLMHBDN_03675 2.8e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PBLMHBDN_03676 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
PBLMHBDN_03677 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
PBLMHBDN_03678 3.5e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PBLMHBDN_03679 4.7e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBLMHBDN_03680 1e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBLMHBDN_03681 1.5e-166 cbrA3 P Periplasmic binding protein
PBLMHBDN_03682 1.7e-57 arsR K transcriptional
PBLMHBDN_03683 4.2e-226 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PBLMHBDN_03684 1.3e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
PBLMHBDN_03685 2.3e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
PBLMHBDN_03686 1.6e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PBLMHBDN_03687 6.2e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PBLMHBDN_03688 5.3e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
PBLMHBDN_03689 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
PBLMHBDN_03690 2.7e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
PBLMHBDN_03691 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PBLMHBDN_03692 1.6e-193 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PBLMHBDN_03693 7.9e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
PBLMHBDN_03694 4.2e-155 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PBLMHBDN_03695 2.5e-290 cydD V ATP-binding protein
PBLMHBDN_03696 2.4e-311 cydD V ATP-binding
PBLMHBDN_03697 2.5e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
PBLMHBDN_03698 4.5e-266 cydA 1.10.3.14 C oxidase, subunit
PBLMHBDN_03699 1e-214 cimH C COG3493 Na citrate symporter
PBLMHBDN_03700 7.3e-155 yxkH G Polysaccharide deacetylase
PBLMHBDN_03701 2.6e-205 msmK P Belongs to the ABC transporter superfamily
PBLMHBDN_03702 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
PBLMHBDN_03703 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PBLMHBDN_03704 3.8e-87 yxkC S Domain of unknown function (DUF4352)
PBLMHBDN_03705 8.2e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PBLMHBDN_03706 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PBLMHBDN_03709 2e-85 yxjI S LURP-one-related
PBLMHBDN_03710 4.1e-217 yxjG 2.1.1.14 E Methionine synthase
PBLMHBDN_03711 2.6e-155 rlmA 2.1.1.187 Q Methyltransferase domain
PBLMHBDN_03712 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PBLMHBDN_03713 1.8e-71 T Domain of unknown function (DUF4163)
PBLMHBDN_03714 4.3e-49 yxiS
PBLMHBDN_03715 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
PBLMHBDN_03716 3.1e-221 citH C Citrate transporter
PBLMHBDN_03717 2e-140 exoK GH16 M licheninase activity
PBLMHBDN_03719 2.2e-106 licT K transcriptional antiterminator
PBLMHBDN_03720 4.1e-21 licT K transcriptional antiterminator
PBLMHBDN_03721 1.6e-219 yxiO S COG2270 Permeases of the major facilitator superfamily
PBLMHBDN_03722 6.9e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
PBLMHBDN_03725 2.7e-61 S SMI1-KNR4 cell-wall
PBLMHBDN_03726 1.6e-48 yxiI S Protein of unknown function (DUF2716)
PBLMHBDN_03727 4.2e-22
PBLMHBDN_03728 1.1e-14 S YxiJ-like protein
PBLMHBDN_03730 1e-78
PBLMHBDN_03731 3.6e-32
PBLMHBDN_03734 2.3e-69 yxiG
PBLMHBDN_03735 2.1e-62 yxxG
PBLMHBDN_03737 1.2e-84 S Protein of unknown function (DUF4240)
PBLMHBDN_03738 2.1e-117
PBLMHBDN_03739 0.0 wapA M COG3209 Rhs family protein
PBLMHBDN_03740 8e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
PBLMHBDN_03741 3.6e-147 yxxF EG EamA-like transporter family
PBLMHBDN_03742 1.8e-72 yxiE T Belongs to the universal stress protein A family
PBLMHBDN_03743 0.0 L HKD family nuclease
PBLMHBDN_03744 5.5e-65 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PBLMHBDN_03745 2.6e-274 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
PBLMHBDN_03746 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
PBLMHBDN_03747 3.6e-285 hutH 4.3.1.3 E Histidine ammonia-lyase
PBLMHBDN_03748 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PBLMHBDN_03749 6.3e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
PBLMHBDN_03750 3.2e-175 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
PBLMHBDN_03751 4.4e-253 lysP E amino acid
PBLMHBDN_03752 8.7e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
PBLMHBDN_03753 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PBLMHBDN_03754 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PBLMHBDN_03755 5.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PBLMHBDN_03756 2.6e-149 yidA S hydrolases of the HAD superfamily
PBLMHBDN_03760 8.4e-23 yxeD
PBLMHBDN_03761 1.3e-34
PBLMHBDN_03762 4.1e-178 fhuD P Periplasmic binding protein
PBLMHBDN_03763 1.3e-57 yxeA S Protein of unknown function (DUF1093)
PBLMHBDN_03764 0.0 yxdM V ABC transporter (permease)
PBLMHBDN_03765 3.6e-140 yxdL V ABC transporter, ATP-binding protein
PBLMHBDN_03766 2.5e-175 T PhoQ Sensor
PBLMHBDN_03767 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PBLMHBDN_03768 1.1e-156 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
PBLMHBDN_03769 2.5e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
PBLMHBDN_03770 3.3e-166 iolH G Xylose isomerase-like TIM barrel
PBLMHBDN_03771 2.6e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PBLMHBDN_03772 6.7e-232 iolF EGP Major facilitator Superfamily
PBLMHBDN_03773 3.4e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PBLMHBDN_03774 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PBLMHBDN_03775 2.7e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PBLMHBDN_03776 1.6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PBLMHBDN_03777 4.8e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PBLMHBDN_03778 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
PBLMHBDN_03779 4.6e-174 iolS C Aldo keto reductase
PBLMHBDN_03780 4.3e-245 csbC EGP Major facilitator Superfamily
PBLMHBDN_03781 0.0 htpG O Molecular chaperone. Has ATPase activity
PBLMHBDN_03783 1.8e-150 IQ Enoyl-(Acyl carrier protein) reductase
PBLMHBDN_03784 2.3e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PBLMHBDN_03785 4.5e-200 desK 2.7.13.3 T Histidine kinase
PBLMHBDN_03786 9.6e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
PBLMHBDN_03787 1.2e-213 yxbF K Bacterial regulatory proteins, tetR family
PBLMHBDN_03788 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
PBLMHBDN_03789 2.8e-142 S PQQ-like domain
PBLMHBDN_03790 1.7e-64 S Family of unknown function (DUF5391)
PBLMHBDN_03791 3e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
PBLMHBDN_03792 3.2e-201 EGP Major facilitator Superfamily
PBLMHBDN_03793 7.6e-74 yxaI S membrane protein domain
PBLMHBDN_03794 2.7e-123 E Ring-cleavage extradiol dioxygenase
PBLMHBDN_03795 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
PBLMHBDN_03796 1.1e-286 ahpF O Alkyl hydroperoxide reductase
PBLMHBDN_03797 5.5e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
PBLMHBDN_03798 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
PBLMHBDN_03799 1.7e-81 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
PBLMHBDN_03800 2.2e-151 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
PBLMHBDN_03801 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PBLMHBDN_03802 1.3e-87 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
PBLMHBDN_03803 5.3e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PBLMHBDN_03804 1.5e-178 S Fusaric acid resistance protein-like
PBLMHBDN_03805 8.1e-63 K ParB-like nuclease domain
PBLMHBDN_03806 6e-21 S Restriction endonuclease
PBLMHBDN_03807 3.7e-96 cca 2.7.7.19, 2.7.7.72 J COG0617 tRNA nucleotidyltransferase poly(A) polymerase
PBLMHBDN_03808 1.2e-237 dgt 3.1.5.1 F dGTP triphosphohydrolase
PBLMHBDN_03809 2.6e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PBLMHBDN_03810 7.9e-08 S YyzF-like protein
PBLMHBDN_03813 4.6e-216 yycP
PBLMHBDN_03814 1e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PBLMHBDN_03815 1.3e-184 C oxidoreductases (related to aryl-alcohol dehydrogenases)
PBLMHBDN_03816 6.9e-86 yycN 2.3.1.128 K Acetyltransferase
PBLMHBDN_03818 3.2e-198 S Histidine kinase
PBLMHBDN_03819 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
PBLMHBDN_03820 1.9e-256 rocE E amino acid
PBLMHBDN_03821 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
PBLMHBDN_03822 2e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PBLMHBDN_03823 5.9e-145 1.14.11.27 P peptidyl-arginine hydroxylation
PBLMHBDN_03824 1.3e-304 S ABC transporter
PBLMHBDN_03825 2.6e-198 S Major Facilitator Superfamily
PBLMHBDN_03826 9.4e-258
PBLMHBDN_03827 2.7e-188 2.7.7.73, 2.7.7.80 H ThiF family
PBLMHBDN_03828 5.6e-248 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
PBLMHBDN_03829 2.1e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PBLMHBDN_03830 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PBLMHBDN_03831 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PBLMHBDN_03832 1.1e-150 yycI S protein conserved in bacteria
PBLMHBDN_03833 7.2e-261 yycH S protein conserved in bacteria
PBLMHBDN_03834 0.0 vicK 2.7.13.3 T Histidine kinase
PBLMHBDN_03835 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PBLMHBDN_03840 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PBLMHBDN_03841 8.5e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PBLMHBDN_03842 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PBLMHBDN_03843 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
PBLMHBDN_03845 1e-16 yycC K YycC-like protein
PBLMHBDN_03846 1.6e-233 M Glycosyltransferase Family 4
PBLMHBDN_03847 4.5e-202 S Ecdysteroid kinase
PBLMHBDN_03848 8e-232 S Carbamoyl-phosphate synthase L chain, ATP binding domain
PBLMHBDN_03849 5.1e-243 M Glycosyltransferase Family 4
PBLMHBDN_03850 1.1e-121 S GlcNAc-PI de-N-acetylase
PBLMHBDN_03851 3.8e-122 KLT COG0515 Serine threonine protein kinase
PBLMHBDN_03852 4.9e-73 rplI J binds to the 23S rRNA
PBLMHBDN_03853 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PBLMHBDN_03854 2.4e-159 yybS S membrane
PBLMHBDN_03856 2.1e-83 cotF M Spore coat protein
PBLMHBDN_03857 8.2e-66 ydeP3 K Transcriptional regulator
PBLMHBDN_03858 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
PBLMHBDN_03860 4.8e-155 S Domain of unknown function (DUF5068)
PBLMHBDN_03861 1.8e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PBLMHBDN_03862 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
PBLMHBDN_03863 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
PBLMHBDN_03864 2.2e-114 K FCD domain
PBLMHBDN_03865 1.8e-71 dinB S PFAM DinB family protein
PBLMHBDN_03866 1e-157 G Major Facilitator Superfamily
PBLMHBDN_03867 2.2e-55 ypaA S Protein of unknown function (DUF1304)
PBLMHBDN_03868 5.6e-115 drgA C nitroreductase
PBLMHBDN_03869 4.1e-69 ydgJ K Winged helix DNA-binding domain
PBLMHBDN_03870 1e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
PBLMHBDN_03871 1.6e-76 yybA 2.3.1.57 K transcriptional
PBLMHBDN_03873 2.4e-161 eaeH M Domain of Unknown Function (DUF1259)
PBLMHBDN_03874 2.3e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
PBLMHBDN_03875 8.6e-162 K Transcriptional regulator
PBLMHBDN_03876 3.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PBLMHBDN_03877 3.6e-94
PBLMHBDN_03878 4.5e-66 S Leucine-rich repeat (LRR) protein
PBLMHBDN_03879 4.2e-19
PBLMHBDN_03880 8.5e-70 isp O Belongs to the peptidase S8 family
PBLMHBDN_03881 2.1e-250 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PBLMHBDN_03882 1.5e-129 ydfC EG EamA-like transporter family
PBLMHBDN_03883 6.7e-113 K Bacterial transcription activator, effector binding domain
PBLMHBDN_03884 7.9e-99 S Protein of unknown function (DUF554)
PBLMHBDN_03885 1.2e-21 yyaL O Highly conserved protein containing a thioredoxin domain
PBLMHBDN_03886 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
PBLMHBDN_03887 3.3e-161 yyaK S CAAX protease self-immunity
PBLMHBDN_03888 2e-247 ydjK G Sugar (and other) transporter
PBLMHBDN_03889 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PBLMHBDN_03890 5.2e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
PBLMHBDN_03891 1.6e-140 xth 3.1.11.2 L exodeoxyribonuclease III
PBLMHBDN_03892 1e-96 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PBLMHBDN_03893 4.1e-104 adaA 3.2.2.21 K Transcriptional regulator
PBLMHBDN_03894 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PBLMHBDN_03895 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PBLMHBDN_03896 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
PBLMHBDN_03897 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PBLMHBDN_03898 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PBLMHBDN_03899 2.3e-33 yyzM S protein conserved in bacteria
PBLMHBDN_03900 1.5e-175 yyaD S Membrane
PBLMHBDN_03901 1.2e-46 4.2.1.103 K FR47-like protein
PBLMHBDN_03902 6.2e-111 yyaC S Sporulation protein YyaC
PBLMHBDN_03903 7.9e-149 spo0J K Belongs to the ParB family
PBLMHBDN_03904 5.8e-135 soj D COG1192 ATPases involved in chromosome partitioning
PBLMHBDN_03905 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PBLMHBDN_03906 6.1e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PBLMHBDN_03907 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PBLMHBDN_03908 2.6e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PBLMHBDN_03909 1.3e-108 jag S single-stranded nucleic acid binding R3H
PBLMHBDN_03910 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PBLMHBDN_03911 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)