ORF_ID e_value Gene_name EC_number CAZy COGs Description
HEEBIOIH_00001 2.9e-18 yrpG C Aldo/keto reductase family
HEEBIOIH_00003 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEEBIOIH_00004 3.9e-11 yqfQ S YqfQ-like protein
HEEBIOIH_00005 8.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEEBIOIH_00006 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEEBIOIH_00007 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HEEBIOIH_00008 8.2e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HEEBIOIH_00009 1.9e-77 zur P Belongs to the Fur family
HEEBIOIH_00010 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HEEBIOIH_00011 3.7e-61 yqfX S membrane
HEEBIOIH_00012 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEEBIOIH_00013 4.4e-46 yqfZ M LysM domain
HEEBIOIH_00014 3.9e-131 yqgB S Protein of unknown function (DUF1189)
HEEBIOIH_00015 4e-73 yqgC S protein conserved in bacteria
HEEBIOIH_00016 3.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HEEBIOIH_00017 1.8e-229 yqgE EGP Major facilitator superfamily
HEEBIOIH_00018 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HEEBIOIH_00019 2.4e-150 pstS P Phosphate
HEEBIOIH_00020 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HEEBIOIH_00021 1.3e-157 pstA P Phosphate transport system permease
HEEBIOIH_00022 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEEBIOIH_00023 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEEBIOIH_00024 7.3e-72 yqzC S YceG-like family
HEEBIOIH_00025 3.5e-50 yqzD
HEEBIOIH_00027 8.1e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HEEBIOIH_00028 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEEBIOIH_00029 2.5e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEEBIOIH_00030 2.5e-09 yqgO
HEEBIOIH_00031 3.1e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HEEBIOIH_00032 4.7e-32 yqgQ S Protein conserved in bacteria
HEEBIOIH_00033 3.4e-180 glcK 2.7.1.2 G Glucokinase
HEEBIOIH_00034 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEEBIOIH_00035 1.6e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HEEBIOIH_00036 8.8e-198 yqgU
HEEBIOIH_00037 6.9e-50 yqgV S Thiamine-binding protein
HEEBIOIH_00038 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HEEBIOIH_00039 2.3e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HEEBIOIH_00040 2e-36 yqgY S Protein of unknown function (DUF2626)
HEEBIOIH_00041 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HEEBIOIH_00043 1.5e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEEBIOIH_00044 2.2e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HEEBIOIH_00045 6.7e-173 corA P Mg2 transporter protein
HEEBIOIH_00046 5e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEEBIOIH_00047 2.4e-57 comGB NU COG1459 Type II secretory pathway, component PulF
HEEBIOIH_00048 1.2e-95 comGB NU COG1459 Type II secretory pathway, component PulF
HEEBIOIH_00049 1.2e-46 comGC U Required for transformation and DNA binding
HEEBIOIH_00050 4.1e-69 gspH NU protein transport across the cell outer membrane
HEEBIOIH_00051 1.3e-57 comGE
HEEBIOIH_00052 6e-45 comGF U Putative Competence protein ComGF
HEEBIOIH_00053 1.2e-43 S ComG operon protein 7
HEEBIOIH_00054 5.2e-26 yqzE S YqzE-like protein
HEEBIOIH_00055 2.8e-53 yqzG S Protein of unknown function (DUF3889)
HEEBIOIH_00056 4.8e-97 yqxM
HEEBIOIH_00057 5.7e-58 sipW 3.4.21.89 U Signal peptidase
HEEBIOIH_00058 4.3e-141 tasA S Cell division protein FtsN
HEEBIOIH_00059 1e-54 sinR K transcriptional
HEEBIOIH_00060 1.2e-24 sinI S Anti-repressor SinI
HEEBIOIH_00061 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HEEBIOIH_00062 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEEBIOIH_00063 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HEEBIOIH_00064 1.9e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEEBIOIH_00065 4.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEEBIOIH_00066 3.3e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
HEEBIOIH_00067 5.7e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HEEBIOIH_00068 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HEEBIOIH_00069 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
HEEBIOIH_00070 2.2e-61 yqhP
HEEBIOIH_00071 1.5e-172 yqhQ S Protein of unknown function (DUF1385)
HEEBIOIH_00072 6.6e-93 yqhR S Conserved membrane protein YqhR
HEEBIOIH_00073 1.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HEEBIOIH_00074 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HEEBIOIH_00075 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEEBIOIH_00076 1.8e-36 yqhV S Protein of unknown function (DUF2619)
HEEBIOIH_00077 4e-170 spoIIIAA S stage III sporulation protein AA
HEEBIOIH_00078 1.1e-84 spoIIIAB S Stage III sporulation protein
HEEBIOIH_00079 7.6e-29 spoIIIAC S stage III sporulation protein AC
HEEBIOIH_00080 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HEEBIOIH_00081 1.3e-197 spoIIIAE S stage III sporulation protein AE
HEEBIOIH_00082 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HEEBIOIH_00083 2.2e-109 spoIIIAG S stage III sporulation protein AG
HEEBIOIH_00084 2.9e-90 spoIIIAH S SpoIIIAH-like protein
HEEBIOIH_00085 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEEBIOIH_00086 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HEEBIOIH_00087 8.1e-67 yqhY S protein conserved in bacteria
HEEBIOIH_00088 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEEBIOIH_00089 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEEBIOIH_00090 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEEBIOIH_00091 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEEBIOIH_00092 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HEEBIOIH_00093 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEEBIOIH_00094 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HEEBIOIH_00095 6.6e-78 argR K Regulates arginine biosynthesis genes
HEEBIOIH_00096 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
HEEBIOIH_00097 2.3e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
HEEBIOIH_00098 3.6e-143 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HEEBIOIH_00100 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HEEBIOIH_00102 6e-27
HEEBIOIH_00103 7.8e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HEEBIOIH_00104 2.3e-128 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEEBIOIH_00105 2.9e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
HEEBIOIH_00106 2.6e-155 hbdA 1.1.1.157 I Dehydrogenase
HEEBIOIH_00107 6.7e-212 mmgC I acyl-CoA dehydrogenase
HEEBIOIH_00108 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HEEBIOIH_00109 8.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HEEBIOIH_00110 8.7e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HEEBIOIH_00111 4e-34 yqzF S Protein of unknown function (DUF2627)
HEEBIOIH_00112 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HEEBIOIH_00113 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HEEBIOIH_00114 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEEBIOIH_00115 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HEEBIOIH_00116 8.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEEBIOIH_00117 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEEBIOIH_00118 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEEBIOIH_00119 1.8e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEEBIOIH_00120 4.4e-152 bmrR K helix_turn_helix, mercury resistance
HEEBIOIH_00121 3.9e-207 norA EGP Major facilitator Superfamily
HEEBIOIH_00122 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEEBIOIH_00123 6e-76 yqiW S Belongs to the UPF0403 family
HEEBIOIH_00124 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HEEBIOIH_00125 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HEEBIOIH_00126 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEEBIOIH_00127 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
HEEBIOIH_00128 8.8e-98 yqjB S protein conserved in bacteria
HEEBIOIH_00130 1e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HEEBIOIH_00131 5.5e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEEBIOIH_00132 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HEEBIOIH_00133 3.5e-42 msrR K Peptide methionine sulfoxide reductase regulator MsrR
HEEBIOIH_00134 8.7e-48 3.4.24.84 O Peptidase family M48
HEEBIOIH_00135 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEEBIOIH_00136 7.1e-101 yxaF K Transcriptional regulator
HEEBIOIH_00137 9.6e-194 yxaG 1.13.11.24 S AraC-like ligand binding domain
HEEBIOIH_00138 7.4e-225 P Protein of unknown function (DUF418)
HEEBIOIH_00139 2.4e-75 yxaI S membrane protein domain
HEEBIOIH_00140 7.2e-60 S Family of unknown function (DUF5391)
HEEBIOIH_00141 9.9e-92 S PQQ-like domain
HEEBIOIH_00142 4e-12 yxaI S membrane protein domain
HEEBIOIH_00143 1.3e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HEEBIOIH_00144 2.7e-208 yxbF K Bacterial regulatory proteins, tetR family
HEEBIOIH_00145 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
HEEBIOIH_00147 0.0 htpG O Molecular chaperone. Has ATPase activity
HEEBIOIH_00148 2.8e-244 csbC EGP Major facilitator Superfamily
HEEBIOIH_00149 2.4e-47 yxcD S Protein of unknown function (DUF2653)
HEEBIOIH_00151 1.9e-175 iolS C Aldo keto reductase
HEEBIOIH_00152 9.5e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HEEBIOIH_00153 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEEBIOIH_00154 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HEEBIOIH_00155 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HEEBIOIH_00156 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HEEBIOIH_00157 8.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HEEBIOIH_00158 6.2e-233 iolF EGP Major facilitator Superfamily
HEEBIOIH_00159 1.8e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HEEBIOIH_00160 3.3e-166 iolH G Xylose isomerase-like TIM barrel
HEEBIOIH_00161 2.1e-146 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HEEBIOIH_00162 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HEEBIOIH_00163 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_00164 1.5e-180 T PhoQ Sensor
HEEBIOIH_00165 9.7e-138 yxdL V ABC transporter, ATP-binding protein
HEEBIOIH_00166 0.0 yxdM V ABC transporter (permease)
HEEBIOIH_00167 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HEEBIOIH_00168 2.3e-176 fhuD P ABC transporter
HEEBIOIH_00169 8.5e-69
HEEBIOIH_00170 5.6e-16 yxeD
HEEBIOIH_00171 1.3e-20 yxeE
HEEBIOIH_00174 1.4e-150 yidA S hydrolases of the HAD superfamily
HEEBIOIH_00175 1e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HEEBIOIH_00176 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEEBIOIH_00177 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEEBIOIH_00178 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HEEBIOIH_00179 2.9e-106 yxeN P COG0765 ABC-type amino acid transport system, permease component
HEEBIOIH_00180 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HEEBIOIH_00181 2.7e-213 yxeP 3.5.1.47 E hydrolase activity
HEEBIOIH_00182 3.4e-247 yxeQ S MmgE/PrpD family
HEEBIOIH_00183 7.1e-198 eutH E Ethanolamine utilisation protein, EutH
HEEBIOIH_00184 2e-152 yxxB S Domain of Unknown Function (DUF1206)
HEEBIOIH_00185 1.8e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEEBIOIH_00186 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEEBIOIH_00187 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEEBIOIH_00188 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HEEBIOIH_00189 6.3e-249 lysP E amino acid
HEEBIOIH_00190 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HEEBIOIH_00191 3.3e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HEEBIOIH_00192 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HEEBIOIH_00193 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
HEEBIOIH_00194 2.8e-76 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HEEBIOIH_00195 1.4e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HEEBIOIH_00196 6.4e-77 L NgoFVII restriction endonuclease
HEEBIOIH_00197 1.7e-96 S GTP binding
HEEBIOIH_00198 4.9e-183 2.1.1.37 H C-5 cytosine-specific DNA methylase
HEEBIOIH_00199 2.8e-49 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HEEBIOIH_00200 1e-20 S Domain of unknown function (DUF5082)
HEEBIOIH_00201 4.7e-39 yxiC S Family of unknown function (DUF5344)
HEEBIOIH_00202 1.1e-303 S nuclease activity
HEEBIOIH_00203 1.1e-77 S SMI1 / KNR4 family
HEEBIOIH_00204 2.9e-40
HEEBIOIH_00205 5.9e-67 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEEBIOIH_00206 2.9e-173 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEEBIOIH_00207 1.1e-72 yxiE T Belongs to the universal stress protein A family
HEEBIOIH_00208 1.4e-162 yxxF EG EamA-like transporter family
HEEBIOIH_00209 0.0 wapA M COG3209 Rhs family protein
HEEBIOIH_00210 4.1e-14 yxiJ S YxiJ-like protein
HEEBIOIH_00211 6.1e-80 wapA M COG3209 Rhs family protein
HEEBIOIH_00212 3.5e-54
HEEBIOIH_00214 7.2e-139
HEEBIOIH_00215 4e-93 S Protein of unknown function (DUF4240)
HEEBIOIH_00216 4.9e-76
HEEBIOIH_00217 8.4e-45
HEEBIOIH_00218 4.3e-68 yxiG
HEEBIOIH_00219 3.4e-52 yxxG
HEEBIOIH_00220 1.9e-38 S Protein of unknown function (DUF2750)
HEEBIOIH_00221 5.3e-16 yxiG
HEEBIOIH_00222 8.3e-13 yxiG
HEEBIOIH_00223 6.5e-135
HEEBIOIH_00224 3.9e-84 yxiI S Protein of unknown function (DUF2716)
HEEBIOIH_00225 7.7e-43 yxiJ S YxiJ-like protein
HEEBIOIH_00228 6.6e-215 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HEEBIOIH_00229 8.1e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HEEBIOIH_00230 2.3e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
HEEBIOIH_00231 1.2e-110
HEEBIOIH_00232 8.8e-139 licT K transcriptional antiterminator
HEEBIOIH_00233 3.3e-143 exoK GH16 M licheninase activity
HEEBIOIH_00234 6.6e-224 citH C Citrate transporter
HEEBIOIH_00235 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HEEBIOIH_00236 3e-47 yxiS
HEEBIOIH_00237 1.2e-102 T Domain of unknown function (DUF4163)
HEEBIOIH_00238 2.1e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEEBIOIH_00239 3.8e-21 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEEBIOIH_00240 3.8e-21 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEEBIOIH_00241 4.3e-08 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEEBIOIH_00242 2e-22 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HEEBIOIH_00243 2e-22 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HEEBIOIH_00244 1.3e-44 yfhJ S WVELL protein
HEEBIOIH_00245 6.2e-20 sspK S reproduction
HEEBIOIH_00246 1.6e-208 yfhI EGP Major facilitator Superfamily
HEEBIOIH_00248 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HEEBIOIH_00249 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HEEBIOIH_00250 7.9e-171 yfhF S nucleoside-diphosphate sugar epimerase
HEEBIOIH_00252 2.1e-25 yfhD S YfhD-like protein
HEEBIOIH_00253 3.9e-107 yfhC C nitroreductase
HEEBIOIH_00254 5.3e-164 yfhB 5.3.3.17 S PhzF family
HEEBIOIH_00255 4.4e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_00256 9.9e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_00257 2.1e-174 yfiY P ABC transporter substrate-binding protein
HEEBIOIH_00258 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEEBIOIH_00259 4.9e-79 yfiV K transcriptional
HEEBIOIH_00260 2.6e-283 yfiU EGP Major facilitator Superfamily
HEEBIOIH_00261 1.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
HEEBIOIH_00262 9.3e-195 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HEEBIOIH_00263 1.3e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEEBIOIH_00264 8.3e-99 padR K transcriptional
HEEBIOIH_00265 8.9e-52 J Acetyltransferase (GNAT) domain
HEEBIOIH_00266 1.8e-204 V COG0842 ABC-type multidrug transport system, permease component
HEEBIOIH_00267 3.3e-209 V ABC-2 family transporter protein
HEEBIOIH_00268 1.5e-169 V ABC transporter, ATP-binding protein
HEEBIOIH_00269 5.4e-113 KT LuxR family transcriptional regulator
HEEBIOIH_00270 1.8e-212 yxjM T Histidine kinase
HEEBIOIH_00272 1.1e-230 S Oxidoreductase
HEEBIOIH_00273 3.2e-183 G Xylose isomerase
HEEBIOIH_00274 3.2e-259 iolT EGP Major facilitator Superfamily
HEEBIOIH_00275 3e-173 K AraC-like ligand binding domain
HEEBIOIH_00276 2.8e-162 yfiE 1.13.11.2 S glyoxalase
HEEBIOIH_00277 6.4e-64 mhqP S DoxX
HEEBIOIH_00278 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEEBIOIH_00279 1.1e-306 yfiB3 V ABC transporter
HEEBIOIH_00280 3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEEBIOIH_00281 7.9e-140 glvR K Helix-turn-helix domain, rpiR family
HEEBIOIH_00282 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEEBIOIH_00283 1.1e-44 yfjA S Belongs to the WXG100 family
HEEBIOIH_00284 6.8e-186 yfjB
HEEBIOIH_00285 1.5e-143 yfjC
HEEBIOIH_00286 6.9e-101 yfjD S Family of unknown function (DUF5381)
HEEBIOIH_00287 5.2e-56 yfjF S UPF0060 membrane protein
HEEBIOIH_00288 1.2e-25 sspH S Belongs to the SspH family
HEEBIOIH_00289 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HEEBIOIH_00290 1.2e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEEBIOIH_00291 4.3e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEEBIOIH_00292 8.5e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEEBIOIH_00293 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEEBIOIH_00294 6.6e-29 yfjL
HEEBIOIH_00295 1.9e-85 yfjM S Psort location Cytoplasmic, score
HEEBIOIH_00296 9.3e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEEBIOIH_00297 5.1e-44 S YfzA-like protein
HEEBIOIH_00298 5.6e-138 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEEBIOIH_00299 1.7e-119 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEEBIOIH_00300 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEEBIOIH_00301 8e-182 corA P Mediates influx of magnesium ions
HEEBIOIH_00302 1.4e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HEEBIOIH_00303 3.8e-153 pdaA G deacetylase
HEEBIOIH_00304 1.1e-26 yfjT
HEEBIOIH_00305 5.4e-222 yfkA S YfkB-like domain
HEEBIOIH_00306 2.3e-148 yfkC M Mechanosensitive ion channel
HEEBIOIH_00307 2e-146 yfkD S YfkD-like protein
HEEBIOIH_00308 6.1e-183 cax P COG0387 Ca2 H antiporter
HEEBIOIH_00309 1.7e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HEEBIOIH_00311 1.3e-143 yihY S Belongs to the UPF0761 family
HEEBIOIH_00312 2.4e-50 yfkI S gas vesicle protein
HEEBIOIH_00313 6.3e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEEBIOIH_00314 1.3e-28 yfkK S Belongs to the UPF0435 family
HEEBIOIH_00315 4.4e-206 ydiM EGP Major facilitator Superfamily
HEEBIOIH_00316 2.6e-86 yfkM 1.11.1.6, 3.5.1.124 S protease
HEEBIOIH_00317 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HEEBIOIH_00318 1.5e-123 yfkO C nitroreductase
HEEBIOIH_00319 1.8e-133 treR K transcriptional
HEEBIOIH_00320 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HEEBIOIH_00321 5.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEEBIOIH_00322 5.9e-113 yfkQ EG Spore germination protein
HEEBIOIH_00323 6e-67 yhdN S Domain of unknown function (DUF1992)
HEEBIOIH_00324 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEEBIOIH_00325 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HEEBIOIH_00326 1.2e-137 map 3.4.11.18 E Methionine aminopeptidase
HEEBIOIH_00327 1.2e-49 yflH S Protein of unknown function (DUF3243)
HEEBIOIH_00328 4.1e-19 yflI
HEEBIOIH_00329 8.9e-18 yflJ S Protein of unknown function (DUF2639)
HEEBIOIH_00330 1.1e-121 yflK S protein conserved in bacteria
HEEBIOIH_00331 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HEEBIOIH_00332 3.3e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HEEBIOIH_00333 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HEEBIOIH_00334 8.5e-227 citM C Citrate transporter
HEEBIOIH_00335 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
HEEBIOIH_00336 1.3e-117 citT T response regulator
HEEBIOIH_00337 2e-286 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HEEBIOIH_00338 5.6e-235 yflS P Sodium:sulfate symporter transmembrane region
HEEBIOIH_00339 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HEEBIOIH_00340 7.6e-58 yflT S Heat induced stress protein YflT
HEEBIOIH_00341 2.9e-24 S Protein of unknown function (DUF3212)
HEEBIOIH_00342 3.3e-164 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HEEBIOIH_00343 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_00344 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_00345 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HEEBIOIH_00346 7.2e-189 yfmJ S N-terminal domain of oxidoreductase
HEEBIOIH_00347 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
HEEBIOIH_00348 2.2e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HEEBIOIH_00349 2.7e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEEBIOIH_00350 1.1e-22 L Transposase
HEEBIOIH_00352 1.3e-27 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HEEBIOIH_00353 1.4e-32 yfmS NT chemotaxis protein
HEEBIOIH_00354 8.8e-81 S Protein of unknown function (DUF2690)
HEEBIOIH_00355 2.3e-20 yjfB S Putative motility protein
HEEBIOIH_00356 1.4e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
HEEBIOIH_00357 3.9e-44 T PhoQ Sensor
HEEBIOIH_00358 4.9e-102 yjgB S Domain of unknown function (DUF4309)
HEEBIOIH_00359 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HEEBIOIH_00360 8.3e-72 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HEEBIOIH_00361 1.6e-94 yjgD S Protein of unknown function (DUF1641)
HEEBIOIH_00364 3.9e-68 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HEEBIOIH_00366 8.9e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HEEBIOIH_00367 4.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEEBIOIH_00368 8.2e-30
HEEBIOIH_00369 1.9e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HEEBIOIH_00370 2.8e-121 ybbM S transport system, permease component
HEEBIOIH_00371 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HEEBIOIH_00372 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
HEEBIOIH_00373 1.3e-90 yjlB S Cupin domain
HEEBIOIH_00374 1.2e-65 yjlC S Protein of unknown function (DUF1641)
HEEBIOIH_00375 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HEEBIOIH_00376 5.1e-278 uxaC 5.3.1.12 G glucuronate isomerase
HEEBIOIH_00377 3.7e-249 yjmB G symporter YjmB
HEEBIOIH_00378 2.5e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HEEBIOIH_00379 3.6e-188 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HEEBIOIH_00380 6.4e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HEEBIOIH_00381 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEEBIOIH_00382 3.7e-227 exuT G Sugar (and other) transporter
HEEBIOIH_00383 6.4e-182 exuR K transcriptional
HEEBIOIH_00384 3.8e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HEEBIOIH_00385 3.8e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HEEBIOIH_00386 1.3e-129 MA20_18170 S membrane transporter protein
HEEBIOIH_00387 2.3e-78 yjoA S DinB family
HEEBIOIH_00388 3e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HEEBIOIH_00389 2.1e-213 S response regulator aspartate phosphatase
HEEBIOIH_00391 1.2e-39 S YCII-related domain
HEEBIOIH_00392 1.6e-158 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HEEBIOIH_00393 1.8e-60 yjqA S Bacterial PH domain
HEEBIOIH_00394 3.7e-108 yjqB S Pfam:DUF867
HEEBIOIH_00395 9.8e-160 ydbD P Catalase
HEEBIOIH_00396 1.6e-111 xkdA E IrrE N-terminal-like domain
HEEBIOIH_00397 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HEEBIOIH_00399 7.8e-157 xkdB K sequence-specific DNA binding
HEEBIOIH_00400 8.5e-109 xkdC L Bacterial dnaA protein
HEEBIOIH_00403 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HEEBIOIH_00404 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEEBIOIH_00405 1.4e-139 xtmA L phage terminase small subunit
HEEBIOIH_00406 9.6e-255 xtmB S phage terminase, large subunit
HEEBIOIH_00407 5.4e-286 yqbA S portal protein
HEEBIOIH_00408 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HEEBIOIH_00409 5.8e-169 xkdG S Phage capsid family
HEEBIOIH_00410 5.6e-62 yqbG S Protein of unknown function (DUF3199)
HEEBIOIH_00411 8.7e-65 yqbH S Domain of unknown function (DUF3599)
HEEBIOIH_00412 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HEEBIOIH_00413 9.3e-77 xkdJ
HEEBIOIH_00414 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HEEBIOIH_00415 6.1e-76 xkdM S Phage tail tube protein
HEEBIOIH_00416 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HEEBIOIH_00417 0.0 xkdO L Transglycosylase SLT domain
HEEBIOIH_00418 3.4e-115 xkdP S Lysin motif
HEEBIOIH_00419 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
HEEBIOIH_00420 4.7e-39 xkdR S Protein of unknown function (DUF2577)
HEEBIOIH_00421 4.1e-69 xkdS S Protein of unknown function (DUF2634)
HEEBIOIH_00422 1.5e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HEEBIOIH_00423 2.4e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HEEBIOIH_00424 4.3e-40
HEEBIOIH_00425 5e-138
HEEBIOIH_00427 6e-11 S Phage uncharacterised protein (Phage_XkdX)
HEEBIOIH_00428 4.3e-35 xhlA S Haemolysin XhlA
HEEBIOIH_00429 9.3e-40 xhlB S SPP1 phage holin
HEEBIOIH_00430 5e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEEBIOIH_00431 6.7e-23 spoIISB S Stage II sporulation protein SB
HEEBIOIH_00432 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HEEBIOIH_00433 7.6e-175 pit P phosphate transporter
HEEBIOIH_00434 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HEEBIOIH_00435 1.2e-236 steT E amino acid
HEEBIOIH_00436 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HEEBIOIH_00437 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEEBIOIH_00438 3.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEEBIOIH_00440 3.2e-213 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEEBIOIH_00441 2.6e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HEEBIOIH_00442 5.1e-153 dppA E D-aminopeptidase
HEEBIOIH_00443 4.5e-155 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEEBIOIH_00444 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEEBIOIH_00445 3.9e-187 dppD P Belongs to the ABC transporter superfamily
HEEBIOIH_00446 0.0 dppE E ABC transporter substrate-binding protein
HEEBIOIH_00448 5.4e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HEEBIOIH_00449 1.4e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HEEBIOIH_00450 2.7e-163 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEEBIOIH_00451 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
HEEBIOIH_00452 3.1e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
HEEBIOIH_00453 1.7e-159 ykgA E Amidinotransferase
HEEBIOIH_00454 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HEEBIOIH_00455 2.4e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEEBIOIH_00456 2.6e-08
HEEBIOIH_00457 2.3e-128 ykjA S Protein of unknown function (DUF421)
HEEBIOIH_00458 5.1e-98 ykkA S Protein of unknown function (DUF664)
HEEBIOIH_00459 2.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEEBIOIH_00460 1.3e-54 ykkC P Multidrug resistance protein
HEEBIOIH_00461 9.1e-50 ykkD P Multidrug resistance protein
HEEBIOIH_00462 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HEEBIOIH_00463 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEEBIOIH_00464 2.4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEEBIOIH_00466 4.8e-70 ohrA O Organic hydroperoxide resistance protein
HEEBIOIH_00467 3.9e-75 ohrR K COG1846 Transcriptional regulators
HEEBIOIH_00468 2.4e-71 ohrB O Organic hydroperoxide resistance protein
HEEBIOIH_00469 6.2e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HEEBIOIH_00470 4.4e-46 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HEEBIOIH_00471 2.1e-43 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEEBIOIH_00472 1e-11 ttdT P PFAM Sodium sulphate symporter
HEEBIOIH_00475 6.7e-60 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEEBIOIH_00476 6.1e-15 yphA
HEEBIOIH_00477 1.9e-10 wecC 1.1.1.336 M UDP-N-acetyl-D-mannosamine dehydrogenase activity
HEEBIOIH_00479 1.6e-11 K Helix-turn-helix XRE-family like proteins
HEEBIOIH_00480 1.1e-09 E IrrE N-terminal-like domain
HEEBIOIH_00481 2.2e-52 dnaA L Helix-turn-helix domain
HEEBIOIH_00483 6.1e-63 soj D Cellulose biosynthesis protein BcsQ
HEEBIOIH_00486 3.7e-66 S Protein of unknown function DUF262
HEEBIOIH_00488 1.8e-107 S response to antibiotic
HEEBIOIH_00489 1.2e-22 rok K Repressor of ComK
HEEBIOIH_00490 6.6e-51 S YolD-like protein
HEEBIOIH_00491 2.9e-232 S impB/mucB/samB family C-terminal domain
HEEBIOIH_00493 6.4e-157 S response regulator aspartate phosphatase
HEEBIOIH_00494 1.3e-41 T cheY-homologous receiver domain
HEEBIOIH_00495 1.1e-72 prsK T Histidine kinase-like ATPases
HEEBIOIH_00496 7.6e-156 ydjC S Abhydrolase domain containing 18
HEEBIOIH_00497 2.4e-27
HEEBIOIH_00498 1.2e-18
HEEBIOIH_00499 3.3e-67 pinR3 L Resolvase, N terminal domain
HEEBIOIH_00502 1e-32
HEEBIOIH_00503 2.9e-75 S Caspase domain
HEEBIOIH_00504 1.3e-23 smf LU DNA mediated transformation
HEEBIOIH_00506 1.5e-35
HEEBIOIH_00509 1.1e-44 S Conserved Protein
HEEBIOIH_00514 3.2e-78 S COG NOG12663 non supervised orthologous group
HEEBIOIH_00518 2.3e-17
HEEBIOIH_00519 9e-14
HEEBIOIH_00520 7.4e-11
HEEBIOIH_00522 1.6e-46 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEEBIOIH_00524 2.3e-08 grxC O Glutaredoxin
HEEBIOIH_00526 2.3e-09
HEEBIOIH_00527 4.3e-26 K Sigma-70, region 4
HEEBIOIH_00528 7.4e-48
HEEBIOIH_00529 1e-10
HEEBIOIH_00533 4.3e-42 S Protein of unknown function (DUF2786)
HEEBIOIH_00538 3e-101 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HEEBIOIH_00546 2.4e-14
HEEBIOIH_00548 2.9e-116 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HEEBIOIH_00550 8.1e-53 V Restriction endonuclease
HEEBIOIH_00552 2.1e-48 S dUTPase
HEEBIOIH_00553 4.9e-166 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HEEBIOIH_00558 1.2e-58 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEEBIOIH_00562 2.1e-212 5.99.1.2 L Bacterial DNA topoisomerase I DNA-binding domain
HEEBIOIH_00565 3.3e-24
HEEBIOIH_00566 5.8e-22
HEEBIOIH_00568 1.8e-13 U TraM recognition site of TraD and TraG
HEEBIOIH_00573 6.7e-80 S COG0790 FOG TPR repeat, SEL1 subfamily
HEEBIOIH_00574 2.4e-10
HEEBIOIH_00576 3.7e-24
HEEBIOIH_00577 7e-108 M Transglycosylase SLT domain
HEEBIOIH_00579 1.1e-190 trsE S COG0433 Predicted ATPase
HEEBIOIH_00580 3.4e-26
HEEBIOIH_00581 6.4e-15 S Uncharacterized protein pXO2-11
HEEBIOIH_00582 3.4e-51 5.4.99.21 S domain, Protein
HEEBIOIH_00583 8.2e-28
HEEBIOIH_00584 1.6e-83 virB11 2.1.1.37 NU Type II/IV secretion system protein
HEEBIOIH_00585 7.8e-33
HEEBIOIH_00586 9e-158 U TraM recognition site of TraD and TraG
HEEBIOIH_00587 7.9e-18
HEEBIOIH_00588 7.8e-14
HEEBIOIH_00589 3.1e-62 S Toprim-like
HEEBIOIH_00596 4e-141 N Pkd domain containing protein
HEEBIOIH_00602 5.8e-27 srtA 3.4.22.70 M Cysteine protease
HEEBIOIH_00603 3.1e-60 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEEBIOIH_00605 5e-238 M nucleic acid phosphodiester bond hydrolysis
HEEBIOIH_00606 1e-29
HEEBIOIH_00607 3.5e-28
HEEBIOIH_00608 2.3e-18
HEEBIOIH_00610 3.9e-210 yjcL S Protein of unknown function (DUF819)
HEEBIOIH_00611 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
HEEBIOIH_00612 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEEBIOIH_00613 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEEBIOIH_00614 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
HEEBIOIH_00615 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HEEBIOIH_00616 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEEBIOIH_00617 1.7e-38
HEEBIOIH_00618 0.0 yjcD 3.6.4.12 L DNA helicase
HEEBIOIH_00619 2.9e-38 spoVIF S Stage VI sporulation protein F
HEEBIOIH_00622 4.3e-56 yjcA S Protein of unknown function (DUF1360)
HEEBIOIH_00623 2.3e-55 cotV S Spore Coat Protein X and V domain
HEEBIOIH_00624 2.1e-30 cotW
HEEBIOIH_00625 6.4e-77 cotX S Spore Coat Protein X and V domain
HEEBIOIH_00626 3.4e-96 cotY S Spore coat protein Z
HEEBIOIH_00627 5.2e-83 cotZ S Spore coat protein
HEEBIOIH_00628 5.9e-54 yjbX S Spore coat protein
HEEBIOIH_00629 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HEEBIOIH_00630 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HEEBIOIH_00631 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEEBIOIH_00632 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HEEBIOIH_00633 6.7e-30 thiS H thiamine diphosphate biosynthetic process
HEEBIOIH_00634 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
HEEBIOIH_00635 4.9e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HEEBIOIH_00636 6.4e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEEBIOIH_00637 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEEBIOIH_00638 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HEEBIOIH_00639 2.6e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEEBIOIH_00640 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEEBIOIH_00641 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HEEBIOIH_00642 7.1e-62 yjbL S Belongs to the UPF0738 family
HEEBIOIH_00643 4.1e-101 yjbK S protein conserved in bacteria
HEEBIOIH_00644 8.2e-86 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEEBIOIH_00645 3.7e-72 yjbI S Bacterial-like globin
HEEBIOIH_00646 4.7e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HEEBIOIH_00647 1.8e-20
HEEBIOIH_00648 0.0 pepF E oligoendopeptidase F
HEEBIOIH_00649 2e-219 yjbF S Competence protein
HEEBIOIH_00650 1.2e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEEBIOIH_00651 6e-112 yjbE P Integral membrane protein TerC family
HEEBIOIH_00652 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEEBIOIH_00653 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEEBIOIH_00654 1.2e-203 yjbB EGP Major Facilitator Superfamily
HEEBIOIH_00655 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HEEBIOIH_00656 3.4e-197 oppD P Belongs to the ABC transporter superfamily
HEEBIOIH_00657 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEEBIOIH_00658 3e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEEBIOIH_00659 6.8e-311 oppA E ABC transporter substrate-binding protein
HEEBIOIH_00660 6.8e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HEEBIOIH_00661 5e-147 yjbA S Belongs to the UPF0736 family
HEEBIOIH_00662 1.8e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEEBIOIH_00663 1.9e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEEBIOIH_00664 1.4e-279 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HEEBIOIH_00665 2.7e-185 appF E Belongs to the ABC transporter superfamily
HEEBIOIH_00666 1.8e-184 appD P Belongs to the ABC transporter superfamily
HEEBIOIH_00667 2.8e-148 yjaZ O Zn-dependent protease
HEEBIOIH_00668 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEEBIOIH_00669 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEEBIOIH_00670 2.7e-22 yjzB
HEEBIOIH_00671 7.3e-26 comZ S ComZ
HEEBIOIH_00672 2.5e-183 med S Transcriptional activator protein med
HEEBIOIH_00673 2.2e-99 yjaV
HEEBIOIH_00674 1.1e-141 yjaU I carboxylic ester hydrolase activity
HEEBIOIH_00675 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HEEBIOIH_00676 9.5e-28 yjzC S YjzC-like protein
HEEBIOIH_00677 8.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEEBIOIH_00678 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HEEBIOIH_00679 1.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEEBIOIH_00680 5.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HEEBIOIH_00681 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HEEBIOIH_00682 1e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEEBIOIH_00683 3.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEEBIOIH_00684 1.7e-88 norB G Major Facilitator Superfamily
HEEBIOIH_00685 2.9e-268 yitY C D-arabinono-1,4-lactone oxidase
HEEBIOIH_00686 1.5e-22 pilT S Proteolipid membrane potential modulator
HEEBIOIH_00687 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HEEBIOIH_00688 2.9e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HEEBIOIH_00689 4.6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HEEBIOIH_00691 1.2e-17 S Protein of unknown function (DUF3813)
HEEBIOIH_00692 5e-73 ipi S Intracellular proteinase inhibitor
HEEBIOIH_00693 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HEEBIOIH_00694 7.9e-157 yitS S protein conserved in bacteria
HEEBIOIH_00695 1.1e-308 nprB 3.4.24.28 E Peptidase M4
HEEBIOIH_00696 1.4e-44 yitR S Domain of unknown function (DUF3784)
HEEBIOIH_00697 2.9e-94
HEEBIOIH_00698 1.5e-58 K Transcriptional regulator PadR-like family
HEEBIOIH_00699 3.4e-97 S Sporulation delaying protein SdpA
HEEBIOIH_00700 3.4e-169
HEEBIOIH_00701 8.5e-94
HEEBIOIH_00702 4.5e-160 cvfB S protein conserved in bacteria
HEEBIOIH_00703 3.3e-54 yajQ S Belongs to the UPF0234 family
HEEBIOIH_00704 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HEEBIOIH_00705 1e-70 yjcF S Acetyltransferase (GNAT) domain
HEEBIOIH_00706 1.8e-156 yitH K Acetyltransferase (GNAT) domain
HEEBIOIH_00707 6.1e-143 yitG EGP Major facilitator Superfamily
HEEBIOIH_00708 3.8e-76 yitG EGP Major facilitator Superfamily
HEEBIOIH_00709 1.3e-30 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HEEBIOIH_00710 7.4e-283 L ATPase involved in DNA repair
HEEBIOIH_00711 3.6e-08
HEEBIOIH_00712 8.1e-235 T Putative serine esterase (DUF676)
HEEBIOIH_00713 4.1e-167
HEEBIOIH_00714 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEEBIOIH_00715 1.1e-09 S YyzF-like protein
HEEBIOIH_00716 3.5e-27
HEEBIOIH_00717 3.7e-232 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEEBIOIH_00719 3.3e-20 yycQ S Protein of unknown function (DUF2651)
HEEBIOIH_00720 9.6e-206 yycP
HEEBIOIH_00721 9.3e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEEBIOIH_00722 1.2e-82 yycN 2.3.1.128 K Acetyltransferase
HEEBIOIH_00723 1.5e-187 S aspartate phosphatase
HEEBIOIH_00725 2e-166 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HEEBIOIH_00726 2.8e-260 rocE E amino acid
HEEBIOIH_00727 7.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HEEBIOIH_00728 3.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HEEBIOIH_00729 1.4e-215 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEEBIOIH_00730 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HEEBIOIH_00731 6.2e-154 yycI S protein conserved in bacteria
HEEBIOIH_00732 2.6e-258 yycH S protein conserved in bacteria
HEEBIOIH_00733 0.0 vicK 2.7.13.3 T Histidine kinase
HEEBIOIH_00734 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_00739 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEEBIOIH_00740 1.6e-54 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEEBIOIH_00741 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HEEBIOIH_00742 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HEEBIOIH_00744 1.9e-15 yycC K YycC-like protein
HEEBIOIH_00745 2.7e-219 yeaN P COG2807 Cyanate permease
HEEBIOIH_00746 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEEBIOIH_00747 1.9e-72 rplI J binds to the 23S rRNA
HEEBIOIH_00748 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HEEBIOIH_00749 8.3e-160 yybS S membrane
HEEBIOIH_00751 4e-14 cotF M Spore coat protein
HEEBIOIH_00752 1.7e-66 ydeP3 K Transcriptional regulator
HEEBIOIH_00753 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HEEBIOIH_00754 2.3e-33
HEEBIOIH_00755 3.2e-27
HEEBIOIH_00757 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HEEBIOIH_00758 3.7e-110 K TipAS antibiotic-recognition domain
HEEBIOIH_00759 2.2e-121
HEEBIOIH_00760 8.6e-66 yybH S SnoaL-like domain
HEEBIOIH_00761 6.9e-121 yybG S Pentapeptide repeat-containing protein
HEEBIOIH_00762 1.1e-101 ynfM EGP Major facilitator Superfamily
HEEBIOIH_00763 5.7e-78 S Metallo-beta-lactamase superfamily
HEEBIOIH_00764 2.8e-76 yybA 2.3.1.57 K transcriptional
HEEBIOIH_00765 4.2e-69 yjcF S Acetyltransferase (GNAT) domain
HEEBIOIH_00766 2.7e-95 yyaS S Membrane
HEEBIOIH_00767 2.1e-91 yyaR K Acetyltransferase (GNAT) domain
HEEBIOIH_00768 1e-65 yyaQ S YjbR
HEEBIOIH_00769 6.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
HEEBIOIH_00770 1.1e-243 tetL EGP Major facilitator Superfamily
HEEBIOIH_00771 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HEEBIOIH_00772 8e-168 yyaK S CAAX protease self-immunity
HEEBIOIH_00773 1.1e-242 EGP Major facilitator superfamily
HEEBIOIH_00774 9.3e-90 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HEEBIOIH_00775 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEEBIOIH_00776 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HEEBIOIH_00777 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
HEEBIOIH_00778 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEEBIOIH_00779 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEEBIOIH_00780 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HEEBIOIH_00781 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEEBIOIH_00782 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEEBIOIH_00783 2.3e-33 yyzM S protein conserved in bacteria
HEEBIOIH_00784 8.1e-177 yyaD S Membrane
HEEBIOIH_00785 1.6e-111 yyaC S Sporulation protein YyaC
HEEBIOIH_00786 2.1e-149 spo0J K Belongs to the ParB family
HEEBIOIH_00787 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HEEBIOIH_00788 4.1e-72 S Bacterial PH domain
HEEBIOIH_00789 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HEEBIOIH_00790 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HEEBIOIH_00791 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEEBIOIH_00792 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEEBIOIH_00793 3.2e-107 jag S single-stranded nucleic acid binding R3H
HEEBIOIH_00794 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEEBIOIH_00795 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEEBIOIH_00796 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEEBIOIH_00797 1.1e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEEBIOIH_00798 2.4e-33 yaaA S S4 domain
HEEBIOIH_00799 9.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEEBIOIH_00800 1.8e-37 yaaB S Domain of unknown function (DUF370)
HEEBIOIH_00801 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEEBIOIH_00802 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEEBIOIH_00803 2.6e-37 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEEBIOIH_00806 6.4e-201 M domain protein
HEEBIOIH_00807 2.2e-21
HEEBIOIH_00808 2.3e-109 virB11 2.1.1.37 NU Type II/IV secretion system protein
HEEBIOIH_00809 2.4e-62
HEEBIOIH_00810 6.2e-57
HEEBIOIH_00811 2.3e-30
HEEBIOIH_00821 1.8e-07
HEEBIOIH_00841 2.2e-28 S Uncharacterized protein conserved in bacteria (DUF2325)
HEEBIOIH_00842 4.4e-07
HEEBIOIH_00843 3.4e-18 S Protein of unknown function (DUF1385)
HEEBIOIH_00845 4.6e-08
HEEBIOIH_00849 6.7e-81 S MTH538 TIR-like domain (DUF1863)
HEEBIOIH_00850 2.2e-186 K SIR2-like domain
HEEBIOIH_00876 2.2e-71
HEEBIOIH_00878 9.5e-126 S COG0457 FOG TPR repeat
HEEBIOIH_00881 6.3e-101 traK U COG3505 Type IV secretory pathway, VirD4 components
HEEBIOIH_00882 3.8e-55 E Zn peptidase
HEEBIOIH_00885 5.9e-148 traI 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEEBIOIH_00889 2.4e-45
HEEBIOIH_00890 8.8e-37
HEEBIOIH_00892 2.6e-13
HEEBIOIH_00893 2.8e-92 yddH CBM50 GM Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEEBIOIH_00894 5.1e-172 traE U Psort location Cytoplasmic, score
HEEBIOIH_00895 2.8e-39
HEEBIOIH_00901 4.1e-62 O unfolded protein binding
HEEBIOIH_00903 2.9e-16
HEEBIOIH_00904 2.2e-52 S Protein of unknown function DUF262
HEEBIOIH_00920 6e-10
HEEBIOIH_00922 3e-115 traA L MobA/MobL family
HEEBIOIH_00923 2.3e-19
HEEBIOIH_00926 5.8e-58 mlaE_1 Q abc transporter, permease
HEEBIOIH_00927 9.6e-11
HEEBIOIH_00928 3.4e-33 K Helix-turn-helix XRE-family like proteins
HEEBIOIH_00929 4.3e-40
HEEBIOIH_00930 5.4e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HEEBIOIH_00932 8.7e-30 cspL K Cold shock
HEEBIOIH_00933 3e-78 carD K Transcription factor
HEEBIOIH_00934 4.6e-35 ydzE EG spore germination
HEEBIOIH_00935 3.2e-161 rhaS5 K AraC-like ligand binding domain
HEEBIOIH_00936 6.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEEBIOIH_00937 8.4e-162 ydeE K AraC family transcriptional regulator
HEEBIOIH_00938 1.5e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEEBIOIH_00939 2.3e-154 ydeG EGP Major facilitator superfamily
HEEBIOIH_00940 6.6e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HEEBIOIH_00941 4e-108
HEEBIOIH_00942 3.2e-09 S SNARE associated Golgi protein
HEEBIOIH_00943 1.8e-14 ptsH G PTS HPr component phosphorylation site
HEEBIOIH_00944 8.8e-85 K Transcriptional regulator C-terminal region
HEEBIOIH_00945 1.6e-152 ydeK EG -transporter
HEEBIOIH_00946 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEEBIOIH_00947 2.3e-72 maoC I N-terminal half of MaoC dehydratase
HEEBIOIH_00948 1.6e-105 ydeN S Serine hydrolase
HEEBIOIH_00949 3e-56 K HxlR-like helix-turn-helix
HEEBIOIH_00950 1.2e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HEEBIOIH_00951 8.2e-57 arsR K transcriptional
HEEBIOIH_00952 1.4e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEEBIOIH_00953 3.5e-73 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HEEBIOIH_00954 1.8e-144 ydfB J GNAT acetyltransferase
HEEBIOIH_00955 2e-158 ydfC EG EamA-like transporter family
HEEBIOIH_00956 6.2e-271 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEEBIOIH_00957 7.2e-115 ydfE S Flavin reductase like domain
HEEBIOIH_00958 1.7e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HEEBIOIH_00959 2.9e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEEBIOIH_00961 3.2e-177 ydfH 2.7.13.3 T Histidine kinase
HEEBIOIH_00962 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEEBIOIH_00963 0.0 ydfJ S drug exporters of the RND superfamily
HEEBIOIH_00964 5.5e-116 S Protein of unknown function (DUF554)
HEEBIOIH_00965 6.6e-145 K Bacterial transcription activator, effector binding domain
HEEBIOIH_00967 5.6e-11 S response regulator aspartate phosphatase
HEEBIOIH_00968 5.4e-13
HEEBIOIH_00971 1.5e-57 L COG3666 Transposase and inactivated derivatives
HEEBIOIH_00972 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEEBIOIH_00973 8.4e-108 ydfN C nitroreductase
HEEBIOIH_00974 1.7e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HEEBIOIH_00975 8.8e-63 mhqP S DoxX
HEEBIOIH_00976 1.6e-55 traF CO Thioredoxin
HEEBIOIH_00977 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HEEBIOIH_00978 6.3e-29
HEEBIOIH_00980 1.3e-25 ydfR S Protein of unknown function (DUF421)
HEEBIOIH_00981 5.1e-28 ydfR S Protein of unknown function (DUF421)
HEEBIOIH_00982 1.5e-121 ydfS S Protein of unknown function (DUF421)
HEEBIOIH_00983 1.9e-74 cotP O Belongs to the small heat shock protein (HSP20) family
HEEBIOIH_00984 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
HEEBIOIH_00985 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HEEBIOIH_00986 2e-98 K Bacterial regulatory proteins, tetR family
HEEBIOIH_00987 3.4e-50 S DoxX-like family
HEEBIOIH_00988 1.7e-84 yycN 2.3.1.128 K Acetyltransferase
HEEBIOIH_00989 1.8e-190 expZ S ABC transporter
HEEBIOIH_00990 1.1e-98 expZ S ABC transporter
HEEBIOIH_00991 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HEEBIOIH_00992 2.5e-89 dinB S DinB family
HEEBIOIH_00993 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
HEEBIOIH_00994 0.0 ydgH S drug exporters of the RND superfamily
HEEBIOIH_00995 2.3e-113 drgA C nitroreductase
HEEBIOIH_00996 7.1e-69 ydgJ K Winged helix DNA-binding domain
HEEBIOIH_00997 1.6e-208 tcaB EGP Major facilitator Superfamily
HEEBIOIH_00998 1.6e-121 ydhB S membrane transporter protein
HEEBIOIH_00999 6.5e-122 ydhC K FCD
HEEBIOIH_01000 2e-241 ydhD M Glycosyl hydrolase
HEEBIOIH_01001 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEEBIOIH_01002 1.3e-125
HEEBIOIH_01003 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HEEBIOIH_01004 4.3e-67 frataxin S Domain of unknown function (DU1801)
HEEBIOIH_01006 8.6e-84 K Acetyltransferase (GNAT) domain
HEEBIOIH_01007 7.6e-180 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HEEBIOIH_01008 9.4e-98 ydhK M Protein of unknown function (DUF1541)
HEEBIOIH_01009 4.6e-200 pbuE EGP Major facilitator Superfamily
HEEBIOIH_01010 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HEEBIOIH_01011 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HEEBIOIH_01012 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEEBIOIH_01013 8.1e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEEBIOIH_01014 1.1e-132 ydhQ K UTRA
HEEBIOIH_01015 7.5e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HEEBIOIH_01016 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEEBIOIH_01017 2.2e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HEEBIOIH_01018 4.6e-157 ydhU P Catalase
HEEBIOIH_01021 3.7e-22 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEEBIOIH_01022 1.1e-42 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEEBIOIH_01023 5.3e-29 bacI V MacB-like periplasmic core domain
HEEBIOIH_01024 1.4e-56 hmrA F Peptidase dimerisation domain
HEEBIOIH_01025 2.2e-21 gerKA1 EG Spore germination protein
HEEBIOIH_01026 4.9e-51 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEEBIOIH_01028 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HEEBIOIH_01029 3.6e-140 ycsF S Belongs to the UPF0271 (lamB) family
HEEBIOIH_01030 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HEEBIOIH_01031 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
HEEBIOIH_01032 1.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HEEBIOIH_01033 1.4e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HEEBIOIH_01034 1.3e-131 kipR K Transcriptional regulator
HEEBIOIH_01035 8.4e-119 ycsK E anatomical structure formation involved in morphogenesis
HEEBIOIH_01037 6.9e-32 yczJ S biosynthesis
HEEBIOIH_01039 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HEEBIOIH_01040 9.2e-172 ydhF S Oxidoreductase
HEEBIOIH_01041 0.0 mtlR K transcriptional regulator, MtlR
HEEBIOIH_01042 1.8e-292 ydaB IQ acyl-CoA ligase
HEEBIOIH_01043 2.2e-97 ydaC Q Methyltransferase domain
HEEBIOIH_01044 7e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEEBIOIH_01045 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HEEBIOIH_01046 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEEBIOIH_01047 6.8e-77 ydaG 1.4.3.5 S general stress protein
HEEBIOIH_01048 4.6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HEEBIOIH_01049 3.6e-45 ydzA EGP Major facilitator Superfamily
HEEBIOIH_01050 2.5e-74 lrpC K Transcriptional regulator
HEEBIOIH_01051 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEEBIOIH_01052 1.4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEEBIOIH_01053 1.2e-89 ydaK T Diguanylate cyclase, GGDEF domain
HEEBIOIH_01054 5e-132 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HEEBIOIH_01055 1e-176 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HEEBIOIH_01056 5.9e-233 ydaM M Glycosyl transferase family group 2
HEEBIOIH_01057 1e-185 ydaN S Bacterial cellulose synthase subunit
HEEBIOIH_01058 3.5e-186 ydaN S Bacterial cellulose synthase subunit
HEEBIOIH_01059 0.0 ydaO E amino acid
HEEBIOIH_01060 5.2e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HEEBIOIH_01061 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HEEBIOIH_01062 3.6e-39
HEEBIOIH_01063 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HEEBIOIH_01065 3.7e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HEEBIOIH_01066 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HEEBIOIH_01068 2.6e-58 ydbB G Cupin domain
HEEBIOIH_01069 2.6e-61 ydbC S Domain of unknown function (DUF4937
HEEBIOIH_01070 1.2e-138 ydbD P Catalase
HEEBIOIH_01071 1.1e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HEEBIOIH_01072 1.5e-294 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HEEBIOIH_01073 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HEEBIOIH_01074 3.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEEBIOIH_01075 2.8e-180 ydbI S AI-2E family transporter
HEEBIOIH_01076 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
HEEBIOIH_01077 2.1e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEEBIOIH_01078 2.7e-52 ydbL
HEEBIOIH_01079 4.8e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HEEBIOIH_01080 1.1e-18 S Fur-regulated basic protein B
HEEBIOIH_01081 2.2e-07 S Fur-regulated basic protein A
HEEBIOIH_01082 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEEBIOIH_01083 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HEEBIOIH_01084 5.6e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HEEBIOIH_01085 5.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEEBIOIH_01086 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEEBIOIH_01087 2.1e-82 ydbS S Bacterial PH domain
HEEBIOIH_01088 8.6e-260 ydbT S Membrane
HEEBIOIH_01089 9e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HEEBIOIH_01090 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEEBIOIH_01091 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HEEBIOIH_01092 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEEBIOIH_01093 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HEEBIOIH_01094 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HEEBIOIH_01095 3e-137 rsbR T Positive regulator of sigma-B
HEEBIOIH_01096 5.2e-57 rsbS T antagonist
HEEBIOIH_01097 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HEEBIOIH_01098 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HEEBIOIH_01099 3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
HEEBIOIH_01100 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HEEBIOIH_01101 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEEBIOIH_01102 1.4e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HEEBIOIH_01103 0.0 yhgF K COG2183 Transcriptional accessory protein
HEEBIOIH_01111 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
HEEBIOIH_01112 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HEEBIOIH_01113 1.6e-236 ktrB P Potassium
HEEBIOIH_01114 1e-38 yiaA S yiaA/B two helix domain
HEEBIOIH_01115 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEEBIOIH_01116 2.7e-272 yubD P Major Facilitator Superfamily
HEEBIOIH_01117 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HEEBIOIH_01119 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEEBIOIH_01120 1.3e-194 yubA S transporter activity
HEEBIOIH_01121 9.7e-183 ygjR S Oxidoreductase
HEEBIOIH_01122 2.6e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HEEBIOIH_01123 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HEEBIOIH_01124 2.5e-272 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HEEBIOIH_01125 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HEEBIOIH_01126 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HEEBIOIH_01127 7.3e-238 mcpA NT chemotaxis protein
HEEBIOIH_01128 1e-292 mcpA NT chemotaxis protein
HEEBIOIH_01129 1.6e-211 mcpA NT chemotaxis protein
HEEBIOIH_01130 1.5e-222 mcpA NT chemotaxis protein
HEEBIOIH_01131 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HEEBIOIH_01132 1e-35
HEEBIOIH_01133 2.1e-72 yugU S Uncharacterised protein family UPF0047
HEEBIOIH_01134 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HEEBIOIH_01135 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HEEBIOIH_01136 1.4e-116 yugP S Zn-dependent protease
HEEBIOIH_01137 3.7e-36
HEEBIOIH_01138 1.2e-52 mstX S Membrane-integrating protein Mistic
HEEBIOIH_01139 8.2e-182 yugO P COG1226 Kef-type K transport systems
HEEBIOIH_01140 1.4e-71 yugN S YugN-like family
HEEBIOIH_01142 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HEEBIOIH_01143 1.4e-228 yugK C Dehydrogenase
HEEBIOIH_01144 1.7e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HEEBIOIH_01145 1.1e-34 yuzA S Domain of unknown function (DUF378)
HEEBIOIH_01146 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HEEBIOIH_01147 2.1e-199 yugH 2.6.1.1 E Aminotransferase
HEEBIOIH_01148 1.6e-85 alaR K Transcriptional regulator
HEEBIOIH_01149 4.9e-156 yugF I Hydrolase
HEEBIOIH_01150 4.6e-39 yugE S Domain of unknown function (DUF1871)
HEEBIOIH_01151 1.7e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HEEBIOIH_01152 1.7e-232 T PhoQ Sensor
HEEBIOIH_01153 4.1e-68 kapB G Kinase associated protein B
HEEBIOIH_01154 2.7e-114 kapD L the KinA pathway to sporulation
HEEBIOIH_01156 1.1e-184 yuxJ EGP Major facilitator Superfamily
HEEBIOIH_01157 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HEEBIOIH_01158 1.8e-74 yuxK S protein conserved in bacteria
HEEBIOIH_01159 1.8e-77 yufK S Family of unknown function (DUF5366)
HEEBIOIH_01160 1.3e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HEEBIOIH_01161 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HEEBIOIH_01162 1.7e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HEEBIOIH_01163 2.7e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HEEBIOIH_01164 4.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HEEBIOIH_01165 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HEEBIOIH_01166 1.3e-233 maeN C COG3493 Na citrate symporter
HEEBIOIH_01167 5e-15
HEEBIOIH_01168 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEEBIOIH_01169 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEEBIOIH_01170 3.4e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEEBIOIH_01171 3.9e-260 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEEBIOIH_01172 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEEBIOIH_01173 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEEBIOIH_01174 3.3e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HEEBIOIH_01175 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HEEBIOIH_01176 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEEBIOIH_01177 0.0 comP 2.7.13.3 T Histidine kinase
HEEBIOIH_01179 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
HEEBIOIH_01181 3.8e-23 yuzC
HEEBIOIH_01182 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HEEBIOIH_01183 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEEBIOIH_01184 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
HEEBIOIH_01185 3.6e-67 yueI S Protein of unknown function (DUF1694)
HEEBIOIH_01186 6.3e-38 yueH S YueH-like protein
HEEBIOIH_01187 6.6e-31 yueG S Spore germination protein gerPA/gerPF
HEEBIOIH_01188 3.9e-188 yueF S transporter activity
HEEBIOIH_01189 5.2e-71 S Protein of unknown function (DUF2283)
HEEBIOIH_01190 1.1e-23 S Protein of unknown function (DUF2642)
HEEBIOIH_01191 1.1e-95 yueE S phosphohydrolase
HEEBIOIH_01192 9.2e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEEBIOIH_01193 6.6e-65 yueC S Family of unknown function (DUF5383)
HEEBIOIH_01194 0.0 esaA S type VII secretion protein EsaA
HEEBIOIH_01195 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HEEBIOIH_01196 6.4e-209 essB S WXG100 protein secretion system (Wss), protein YukC
HEEBIOIH_01197 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HEEBIOIH_01198 2.8e-45 esxA S Belongs to the WXG100 family
HEEBIOIH_01199 2.8e-227 yukF QT Transcriptional regulator
HEEBIOIH_01200 2.6e-203 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HEEBIOIH_01201 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HEEBIOIH_01202 4.2e-35 mbtH S MbtH-like protein
HEEBIOIH_01203 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEEBIOIH_01204 6.8e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HEEBIOIH_01205 2.2e-311 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HEEBIOIH_01206 4.7e-224 entC 5.4.4.2 HQ Isochorismate synthase
HEEBIOIH_01207 5.2e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEEBIOIH_01208 3.9e-167 besA S Putative esterase
HEEBIOIH_01209 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HEEBIOIH_01210 9.7e-93 bioY S Biotin biosynthesis protein
HEEBIOIH_01211 3.9e-211 yuiF S antiporter
HEEBIOIH_01212 2.2e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HEEBIOIH_01213 2e-77 yuiD S protein conserved in bacteria
HEEBIOIH_01214 6.8e-116 yuiC S protein conserved in bacteria
HEEBIOIH_01215 1.1e-26 yuiB S Putative membrane protein
HEEBIOIH_01216 1.6e-235 yumB 1.6.99.3 C NADH dehydrogenase
HEEBIOIH_01217 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
HEEBIOIH_01219 1.8e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEEBIOIH_01220 6.1e-114 paiB K Putative FMN-binding domain
HEEBIOIH_01221 4.3e-49 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEEBIOIH_01222 3.7e-63 erpA S Belongs to the HesB IscA family
HEEBIOIH_01223 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEEBIOIH_01224 1e-197 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEEBIOIH_01225 3.2e-39 yuzB S Belongs to the UPF0349 family
HEEBIOIH_01226 7.7e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HEEBIOIH_01227 1.1e-55 yuzD S protein conserved in bacteria
HEEBIOIH_01228 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HEEBIOIH_01229 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HEEBIOIH_01230 4.3e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEEBIOIH_01231 3.4e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEEBIOIH_01232 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
HEEBIOIH_01233 8.5e-198 yutH S Spore coat protein
HEEBIOIH_01234 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HEEBIOIH_01235 3.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEEBIOIH_01236 1e-75 yutE S Protein of unknown function DUF86
HEEBIOIH_01237 1.1e-46 yutD S protein conserved in bacteria
HEEBIOIH_01238 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEEBIOIH_01239 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HEEBIOIH_01240 1.3e-195 lytH M Peptidase, M23
HEEBIOIH_01241 6.6e-131 yunB S Sporulation protein YunB (Spo_YunB)
HEEBIOIH_01242 9.2e-44 yunC S Domain of unknown function (DUF1805)
HEEBIOIH_01243 1.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HEEBIOIH_01244 5.9e-141 yunE S membrane transporter protein
HEEBIOIH_01245 1.3e-170 yunF S Protein of unknown function DUF72
HEEBIOIH_01246 6.6e-46 yunG
HEEBIOIH_01247 6.2e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HEEBIOIH_01248 3.2e-300 pucR QT COG2508 Regulator of polyketide synthase expression
HEEBIOIH_01249 3.9e-235 pbuX F Permease family
HEEBIOIH_01250 1.5e-220 pbuX F xanthine
HEEBIOIH_01251 3.5e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HEEBIOIH_01252 1e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HEEBIOIH_01254 9e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HEEBIOIH_01255 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HEEBIOIH_01256 4.3e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HEEBIOIH_01257 1.2e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HEEBIOIH_01258 1.5e-186 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HEEBIOIH_01259 8.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HEEBIOIH_01260 2.2e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEEBIOIH_01261 3.8e-167 bsn L Ribonuclease
HEEBIOIH_01262 1.9e-23 S branched-chain amino acid
HEEBIOIH_01263 9.3e-74 azlC E AzlC protein
HEEBIOIH_01264 1.2e-157 gntR9 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEEBIOIH_01265 8.8e-36 L COG3666 Transposase and inactivated derivatives
HEEBIOIH_01266 9.5e-67 L COG3666 Transposase and inactivated derivatives
HEEBIOIH_01267 4.1e-42 S B3/4 domain
HEEBIOIH_01268 1.8e-170 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E methionine gamma-lyase
HEEBIOIH_01269 1.3e-22 I Fatty acid desaturase
HEEBIOIH_01270 9e-80 I Fatty acid desaturase
HEEBIOIH_01272 1.5e-195 msmX P Belongs to the ABC transporter superfamily
HEEBIOIH_01273 7.3e-135 yurK K UTRA
HEEBIOIH_01274 9e-148 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HEEBIOIH_01275 1.5e-152 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HEEBIOIH_01276 1.1e-62 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HEEBIOIH_01277 5.7e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HEEBIOIH_01278 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HEEBIOIH_01279 1.9e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HEEBIOIH_01281 1e-41
HEEBIOIH_01282 1.1e-72 L Molecular Function DNA binding, Biological Process DNA recombination
HEEBIOIH_01283 2.8e-62 L Molecular Function DNA binding, Biological Process DNA recombination
HEEBIOIH_01284 1.9e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEEBIOIH_01285 3.6e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
HEEBIOIH_01286 3.5e-271 sufB O FeS cluster assembly
HEEBIOIH_01287 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HEEBIOIH_01288 7.9e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEEBIOIH_01289 9.1e-245 sufD O assembly protein SufD
HEEBIOIH_01290 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HEEBIOIH_01291 5.6e-46 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEEBIOIH_01292 1.8e-145 metQ P Belongs to the NlpA lipoprotein family
HEEBIOIH_01293 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HEEBIOIH_01294 2.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEEBIOIH_01295 3.2e-56 yusD S SCP-2 sterol transfer family
HEEBIOIH_01296 1.2e-54 traF CO Thioredoxin
HEEBIOIH_01297 1.4e-72 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HEEBIOIH_01298 2.4e-39 yusG S Protein of unknown function (DUF2553)
HEEBIOIH_01299 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HEEBIOIH_01300 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HEEBIOIH_01301 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HEEBIOIH_01302 3.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HEEBIOIH_01303 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HEEBIOIH_01304 8.1e-09 S YuzL-like protein
HEEBIOIH_01305 1.2e-163 fadM E Proline dehydrogenase
HEEBIOIH_01306 5.1e-40
HEEBIOIH_01307 1.6e-52 yusN M Coat F domain
HEEBIOIH_01308 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
HEEBIOIH_01309 4.2e-292 yusP P Major facilitator superfamily
HEEBIOIH_01310 1.8e-63 yusQ S Tautomerase enzyme
HEEBIOIH_01311 2.9e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEEBIOIH_01312 8.2e-157 yusT K LysR substrate binding domain
HEEBIOIH_01313 6.6e-47 yusU S Protein of unknown function (DUF2573)
HEEBIOIH_01314 1e-153 yusV 3.6.3.34 HP ABC transporter
HEEBIOIH_01315 3.3e-66 S YusW-like protein
HEEBIOIH_01316 1.6e-300 pepF2 E COG1164 Oligoendopeptidase F
HEEBIOIH_01317 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEEBIOIH_01318 2.7e-79 dps P Ferritin-like domain
HEEBIOIH_01319 4.4e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEEBIOIH_01320 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_01321 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
HEEBIOIH_01322 4.8e-157 yuxN K Transcriptional regulator
HEEBIOIH_01323 9.6e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEEBIOIH_01324 3.9e-24 S Protein of unknown function (DUF3970)
HEEBIOIH_01325 2.6e-245 gerAA EG Spore germination protein
HEEBIOIH_01326 3.8e-196 gerAB E Spore germination protein
HEEBIOIH_01327 5e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
HEEBIOIH_01328 6.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEEBIOIH_01329 1.6e-186 vraS 2.7.13.3 T Histidine kinase
HEEBIOIH_01330 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HEEBIOIH_01331 1.2e-123 liaG S Putative adhesin
HEEBIOIH_01332 9.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HEEBIOIH_01333 7.3e-62 liaI S membrane
HEEBIOIH_01334 1.4e-226 yvqJ EGP Major facilitator Superfamily
HEEBIOIH_01335 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
HEEBIOIH_01336 2.7e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HEEBIOIH_01337 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_01338 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HEEBIOIH_01339 7.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEEBIOIH_01340 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HEEBIOIH_01341 0.0 T PhoQ Sensor
HEEBIOIH_01342 8.1e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_01343 3.6e-22
HEEBIOIH_01344 4e-96 yvrI K RNA polymerase
HEEBIOIH_01345 6.9e-19 S YvrJ protein family
HEEBIOIH_01346 1.4e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
HEEBIOIH_01347 1.3e-64 yvrL S Regulatory protein YrvL
HEEBIOIH_01348 1.2e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HEEBIOIH_01349 2.1e-123 macB V ABC transporter, ATP-binding protein
HEEBIOIH_01350 6.9e-175 M Efflux transporter rnd family, mfp subunit
HEEBIOIH_01351 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HEEBIOIH_01352 3.8e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_01353 1.3e-180 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_01354 2.6e-177 fhuD P ABC transporter
HEEBIOIH_01355 4.9e-236 yvsH E Arginine ornithine antiporter
HEEBIOIH_01356 6.5e-16 S Small spore protein J (Spore_SspJ)
HEEBIOIH_01357 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HEEBIOIH_01358 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEEBIOIH_01359 2e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HEEBIOIH_01360 1.4e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HEEBIOIH_01361 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
HEEBIOIH_01362 3.2e-155 yvgN S reductase
HEEBIOIH_01363 5.4e-86 yvgO
HEEBIOIH_01364 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HEEBIOIH_01365 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HEEBIOIH_01366 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEEBIOIH_01367 0.0 helD 3.6.4.12 L DNA helicase
HEEBIOIH_01368 4.1e-107 yvgT S membrane
HEEBIOIH_01369 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
HEEBIOIH_01370 2.7e-104 bdbD O Thioredoxin
HEEBIOIH_01371 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HEEBIOIH_01372 0.0 copA 3.6.3.54 P P-type ATPase
HEEBIOIH_01373 5.9e-29 copZ P Copper resistance protein CopZ
HEEBIOIH_01374 2.2e-48 csoR S transcriptional
HEEBIOIH_01375 4e-195 yvaA 1.1.1.371 S Oxidoreductase
HEEBIOIH_01376 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEEBIOIH_01377 0.0 yvaC S Fusaric acid resistance protein-like
HEEBIOIH_01378 1.3e-72 yvaD S Family of unknown function (DUF5360)
HEEBIOIH_01379 2.4e-54 yvaE P Small Multidrug Resistance protein
HEEBIOIH_01380 4.3e-98 K Bacterial regulatory proteins, tetR family
HEEBIOIH_01381 8.5e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HEEBIOIH_01383 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HEEBIOIH_01384 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEEBIOIH_01385 9.6e-143 est 3.1.1.1 S Carboxylesterase
HEEBIOIH_01386 2.4e-23 secG U Preprotein translocase subunit SecG
HEEBIOIH_01387 1.5e-151 yvaM S Serine aminopeptidase, S33
HEEBIOIH_01388 9.8e-36 yvzC K Transcriptional
HEEBIOIH_01389 4e-69 K transcriptional
HEEBIOIH_01390 1.5e-68 yvaO K Cro/C1-type HTH DNA-binding domain
HEEBIOIH_01391 2.2e-54 yodB K transcriptional
HEEBIOIH_01392 1.2e-19 NT chemotaxis protein
HEEBIOIH_01393 2.2e-170 NT chemotaxis protein
HEEBIOIH_01394 1.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEEBIOIH_01395 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEEBIOIH_01396 1.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEEBIOIH_01397 2.7e-208 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEEBIOIH_01398 7.4e-60 yvbF K Belongs to the GbsR family
HEEBIOIH_01399 7.9e-13 S Sporulation delaying protein SdpA
HEEBIOIH_01400 4.9e-171
HEEBIOIH_01401 4.4e-08
HEEBIOIH_01402 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HEEBIOIH_01403 4.5e-45 sdpR K transcriptional
HEEBIOIH_01404 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEEBIOIH_01405 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEEBIOIH_01406 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HEEBIOIH_01407 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEEBIOIH_01408 3.5e-97 yvbF K Belongs to the GbsR family
HEEBIOIH_01409 6e-101 yvbG U UPF0056 membrane protein
HEEBIOIH_01410 1.9e-112 yvbH S YvbH-like oligomerisation region
HEEBIOIH_01411 2.2e-120 exoY M Membrane
HEEBIOIH_01412 6.2e-252 tcaA S response to antibiotic
HEEBIOIH_01413 9.1e-75 yvbK 3.1.3.25 K acetyltransferase
HEEBIOIH_01414 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEEBIOIH_01415 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HEEBIOIH_01416 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEEBIOIH_01417 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HEEBIOIH_01418 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEEBIOIH_01419 1.3e-182 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEEBIOIH_01420 4.8e-252 araE EGP Major facilitator Superfamily
HEEBIOIH_01421 2.1e-202 araR K transcriptional
HEEBIOIH_01422 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEEBIOIH_01423 6.7e-159 yvbU K Transcriptional regulator
HEEBIOIH_01424 2.7e-155 yvbV EG EamA-like transporter family
HEEBIOIH_01425 1.4e-240 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HEEBIOIH_01426 4.7e-188 yvbX S Glycosyl hydrolase
HEEBIOIH_01427 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEEBIOIH_01428 1e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HEEBIOIH_01429 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEEBIOIH_01430 1.6e-45 S Protein of unknown function (DUF2812)
HEEBIOIH_01431 2e-31 K Transcriptional regulator PadR-like family
HEEBIOIH_01432 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEEBIOIH_01433 7.1e-198 desK 2.7.13.3 T Histidine kinase
HEEBIOIH_01434 5.3e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
HEEBIOIH_01435 8.1e-160 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HEEBIOIH_01436 9.8e-157 rsbQ S Alpha/beta hydrolase family
HEEBIOIH_01437 1.5e-193 rsbU 3.1.3.3 T response regulator
HEEBIOIH_01438 3.2e-250 galA 3.2.1.89 G arabinogalactan
HEEBIOIH_01439 0.0 lacA 3.2.1.23 G beta-galactosidase
HEEBIOIH_01440 7.2e-150 ganQ P transport
HEEBIOIH_01441 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
HEEBIOIH_01442 8.8e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
HEEBIOIH_01443 1.8e-184 lacR K Transcriptional regulator
HEEBIOIH_01444 1e-112 yvfI K COG2186 Transcriptional regulators
HEEBIOIH_01445 5.7e-308 yvfH C L-lactate permease
HEEBIOIH_01446 2.5e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HEEBIOIH_01447 1e-31 yvfG S YvfG protein
HEEBIOIH_01448 5.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
HEEBIOIH_01449 6.2e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HEEBIOIH_01450 2.1e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HEEBIOIH_01451 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEEBIOIH_01452 3.8e-255 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEEBIOIH_01453 4.6e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HEEBIOIH_01454 1e-201 epsI GM pyruvyl transferase
HEEBIOIH_01455 2.9e-193 epsH GT2 S Glycosyltransferase like family 2
HEEBIOIH_01456 5.4e-206 epsG S EpsG family
HEEBIOIH_01457 2.9e-218 epsF GT4 M Glycosyl transferases group 1
HEEBIOIH_01458 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEEBIOIH_01459 1.2e-221 epsD GT4 M Glycosyl transferase 4-like
HEEBIOIH_01460 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HEEBIOIH_01461 3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HEEBIOIH_01462 2.2e-120 ywqC M biosynthesis protein
HEEBIOIH_01463 3.1e-75 slr K transcriptional
HEEBIOIH_01464 5.3e-278 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HEEBIOIH_01466 1.7e-92 padC Q Phenolic acid decarboxylase
HEEBIOIH_01467 4.2e-72 MA20_18690 S Protein of unknown function (DUF3237)
HEEBIOIH_01468 8.4e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HEEBIOIH_01469 5.9e-263 pbpE V Beta-lactamase
HEEBIOIH_01470 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HEEBIOIH_01471 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HEEBIOIH_01472 3.3e-294 yveA E amino acid
HEEBIOIH_01473 1.4e-104 yvdT K Transcriptional regulator
HEEBIOIH_01474 1.6e-49 ykkC P Small Multidrug Resistance protein
HEEBIOIH_01475 2.1e-49 sugE P Small Multidrug Resistance protein
HEEBIOIH_01476 1.3e-72 yvdQ S Protein of unknown function (DUF3231)
HEEBIOIH_01478 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEEBIOIH_01479 1.3e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HEEBIOIH_01480 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HEEBIOIH_01481 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HEEBIOIH_01482 1.4e-153 malA S Protein of unknown function (DUF1189)
HEEBIOIH_01483 9.5e-147 malD P transport
HEEBIOIH_01484 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
HEEBIOIH_01485 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HEEBIOIH_01486 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HEEBIOIH_01487 3.3e-172 yvdE K Transcriptional regulator
HEEBIOIH_01488 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
HEEBIOIH_01489 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HEEBIOIH_01490 3.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HEEBIOIH_01491 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HEEBIOIH_01492 8.7e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEEBIOIH_01493 1.6e-302 yxdM V ABC transporter (permease)
HEEBIOIH_01494 4.6e-23 yxdM V ABC transporter (permease)
HEEBIOIH_01495 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HEEBIOIH_01496 7.5e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HEEBIOIH_01497 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_01498 2.8e-31
HEEBIOIH_01499 2.2e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HEEBIOIH_01500 1.6e-36 crh G Phosphocarrier protein Chr
HEEBIOIH_01501 4.1e-170 whiA K May be required for sporulation
HEEBIOIH_01502 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HEEBIOIH_01503 5.7e-166 rapZ S Displays ATPase and GTPase activities
HEEBIOIH_01504 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEEBIOIH_01505 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEEBIOIH_01506 1.4e-97 usp CBM50 M protein conserved in bacteria
HEEBIOIH_01507 1e-276 S COG0457 FOG TPR repeat
HEEBIOIH_01508 0.0 msbA2 3.6.3.44 V ABC transporter
HEEBIOIH_01510 0.0
HEEBIOIH_01511 4.7e-118
HEEBIOIH_01512 8.8e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HEEBIOIH_01513 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEEBIOIH_01514 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEEBIOIH_01515 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEEBIOIH_01516 1.8e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HEEBIOIH_01517 3.8e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEEBIOIH_01518 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEEBIOIH_01519 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEEBIOIH_01520 3.8e-139 yvpB NU protein conserved in bacteria
HEEBIOIH_01521 1.5e-118 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HEEBIOIH_01522 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HEEBIOIH_01523 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HEEBIOIH_01524 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
HEEBIOIH_01525 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEEBIOIH_01526 2.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEEBIOIH_01527 8.3e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEEBIOIH_01528 1.2e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEEBIOIH_01529 3.6e-134 yvoA K transcriptional
HEEBIOIH_01530 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HEEBIOIH_01531 4.2e-83 adcR K helix_turn_helix multiple antibiotic resistance protein
HEEBIOIH_01532 3.8e-229 cypX 1.14.15.13 C Cytochrome P450
HEEBIOIH_01533 1.8e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HEEBIOIH_01534 7.4e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
HEEBIOIH_01535 2.7e-203 yvmA EGP Major facilitator Superfamily
HEEBIOIH_01536 1.2e-50 yvlD S Membrane
HEEBIOIH_01537 2.6e-26 pspB KT PspC domain
HEEBIOIH_01538 2.4e-166 yvlB S Putative adhesin
HEEBIOIH_01539 8e-49 yvlA
HEEBIOIH_01540 5.7e-33 yvkN
HEEBIOIH_01541 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEEBIOIH_01542 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEEBIOIH_01543 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEEBIOIH_01544 1.2e-30 csbA S protein conserved in bacteria
HEEBIOIH_01545 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HEEBIOIH_01546 1e-99 yvkB K Transcriptional regulator
HEEBIOIH_01547 3.3e-226 yvkA EGP Major facilitator Superfamily
HEEBIOIH_01548 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEEBIOIH_01549 5.3e-56 swrA S Swarming motility protein
HEEBIOIH_01550 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HEEBIOIH_01551 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEEBIOIH_01552 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HEEBIOIH_01553 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HEEBIOIH_01554 7.1e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HEEBIOIH_01555 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEEBIOIH_01556 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEEBIOIH_01557 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEEBIOIH_01558 4.6e-51
HEEBIOIH_01559 1.9e-08 fliT S bacterial-type flagellum organization
HEEBIOIH_01560 1.9e-68 fliS N flagellar protein FliS
HEEBIOIH_01561 7.7e-248 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HEEBIOIH_01562 1.2e-52 flaG N flagellar protein FlaG
HEEBIOIH_01563 9.4e-115 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEEBIOIH_01564 1.7e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HEEBIOIH_01565 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HEEBIOIH_01566 5.7e-50 yviE
HEEBIOIH_01567 7.8e-155 flgL N Belongs to the bacterial flagellin family
HEEBIOIH_01568 4.6e-264 flgK N flagellar hook-associated protein
HEEBIOIH_01569 2.4e-78 flgN NOU FlgN protein
HEEBIOIH_01570 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
HEEBIOIH_01571 7e-74 yvyF S flagellar protein
HEEBIOIH_01572 2.7e-129 comFC S Phosphoribosyl transferase domain
HEEBIOIH_01573 5.7e-46 comFB S Late competence development protein ComFB
HEEBIOIH_01574 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HEEBIOIH_01575 2.1e-154 degV S protein conserved in bacteria
HEEBIOIH_01576 1e-125 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEEBIOIH_01577 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HEEBIOIH_01578 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HEEBIOIH_01579 6e-163 yvhJ K Transcriptional regulator
HEEBIOIH_01580 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HEEBIOIH_01581 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HEEBIOIH_01582 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HEEBIOIH_01583 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
HEEBIOIH_01584 5.4e-262 tuaE M Teichuronic acid biosynthesis protein
HEEBIOIH_01585 7.6e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEEBIOIH_01586 1.7e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HEEBIOIH_01587 5.7e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEEBIOIH_01588 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEEBIOIH_01589 5.6e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEEBIOIH_01590 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HEEBIOIH_01591 6e-38
HEEBIOIH_01592 4e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HEEBIOIH_01593 1e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEEBIOIH_01594 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEEBIOIH_01595 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HEEBIOIH_01596 1.4e-256 ggaA M Glycosyltransferase like family 2
HEEBIOIH_01598 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEEBIOIH_01599 2.2e-277 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEEBIOIH_01600 1.1e-150 tagG GM Transport permease protein
HEEBIOIH_01601 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEEBIOIH_01602 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HEEBIOIH_01603 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HEEBIOIH_01604 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEEBIOIH_01605 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEEBIOIH_01606 3.5e-260
HEEBIOIH_01607 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEEBIOIH_01608 4.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HEEBIOIH_01609 5.3e-262 gerBA EG Spore germination protein
HEEBIOIH_01610 1.3e-191 gerBB E Spore germination protein
HEEBIOIH_01611 1.4e-206 gerAC S Spore germination protein
HEEBIOIH_01612 1.7e-246 ywtG EGP Major facilitator Superfamily
HEEBIOIH_01613 2.4e-170 ywtF K Transcriptional regulator
HEEBIOIH_01614 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HEEBIOIH_01615 6.3e-21 ykuL S CBS domain
HEEBIOIH_01617 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HEEBIOIH_01618 1e-210 yttB EGP Major facilitator Superfamily
HEEBIOIH_01619 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HEEBIOIH_01620 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HEEBIOIH_01621 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEEBIOIH_01622 2.1e-51 ytwF P Sulfurtransferase
HEEBIOIH_01623 3.4e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HEEBIOIH_01624 4.4e-144 amyC P ABC transporter (permease)
HEEBIOIH_01625 6.2e-168 amyD P ABC transporter
HEEBIOIH_01626 7.3e-247 msmE G Bacterial extracellular solute-binding protein
HEEBIOIH_01627 1.8e-187 msmR K Transcriptional regulator
HEEBIOIH_01628 1.9e-172 ytaP S Acetyl xylan esterase (AXE1)
HEEBIOIH_01629 2.9e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HEEBIOIH_01630 5.1e-251 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HEEBIOIH_01631 4.3e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEEBIOIH_01632 3.8e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HEEBIOIH_01633 6.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HEEBIOIH_01634 2.4e-220 bioI 1.14.14.46 C Cytochrome P450
HEEBIOIH_01635 6.2e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HEEBIOIH_01636 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HEEBIOIH_01637 9.3e-286 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HEEBIOIH_01638 3.3e-135 ytdP K Transcriptional regulator
HEEBIOIH_01639 9.5e-278 ytdP K Transcriptional regulator
HEEBIOIH_01640 5e-65 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HEEBIOIH_01641 4.2e-95 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HEEBIOIH_01642 2.5e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HEEBIOIH_01643 5.6e-71 yteS G transport
HEEBIOIH_01644 8.5e-198 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HEEBIOIH_01645 7e-76 yteU S Integral membrane protein
HEEBIOIH_01646 3.1e-26 yteV S Sporulation protein Cse60
HEEBIOIH_01647 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HEEBIOIH_01648 9e-231 ytfP S HI0933-like protein
HEEBIOIH_01649 2.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEEBIOIH_01650 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEEBIOIH_01651 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HEEBIOIH_01652 4.8e-131 ythP V ABC transporter
HEEBIOIH_01653 4.9e-202 ythQ U Bacterial ABC transporter protein EcsB
HEEBIOIH_01654 2.1e-225 pbuO S permease
HEEBIOIH_01655 3.9e-270 pepV 3.5.1.18 E Dipeptidase
HEEBIOIH_01656 1.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEEBIOIH_01657 3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HEEBIOIH_01658 2.2e-165 ytlQ
HEEBIOIH_01659 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HEEBIOIH_01660 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HEEBIOIH_01661 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HEEBIOIH_01662 2e-45 ytzH S YtzH-like protein
HEEBIOIH_01663 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEEBIOIH_01664 2.7e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HEEBIOIH_01665 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HEEBIOIH_01666 2.2e-51 ytzB S small secreted protein
HEEBIOIH_01667 1.9e-116 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HEEBIOIH_01668 2.3e-78 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HEEBIOIH_01669 3.5e-21 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HEEBIOIH_01670 6.7e-48 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HEEBIOIH_01671 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HEEBIOIH_01672 4.8e-148 ytpQ S Belongs to the UPF0354 family
HEEBIOIH_01673 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEEBIOIH_01674 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HEEBIOIH_01675 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HEEBIOIH_01676 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEEBIOIH_01677 6.6e-17 ytxH S COG4980 Gas vesicle protein
HEEBIOIH_01678 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
HEEBIOIH_01679 1.1e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HEEBIOIH_01680 3.8e-182 ccpA K catabolite control protein A
HEEBIOIH_01681 2.1e-146 motA N flagellar motor
HEEBIOIH_01682 5.2e-125 motS N Flagellar motor protein
HEEBIOIH_01683 5.4e-225 acuC BQ histone deacetylase
HEEBIOIH_01684 3.5e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HEEBIOIH_01685 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HEEBIOIH_01686 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEEBIOIH_01687 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEEBIOIH_01689 1.4e-33 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEEBIOIH_01690 4.4e-40 vpr O Belongs to the peptidase S8 family
HEEBIOIH_01695 2e-08
HEEBIOIH_01702 1.3e-09
HEEBIOIH_01703 7.8e-08
HEEBIOIH_01712 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEEBIOIH_01713 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HEEBIOIH_01714 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HEEBIOIH_01715 2.9e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HEEBIOIH_01716 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEEBIOIH_01717 9.9e-77 tspO T membrane
HEEBIOIH_01718 8.2e-204 cotI S Spore coat protein
HEEBIOIH_01719 3.4e-216 cotSA M Glycosyl transferases group 1
HEEBIOIH_01720 1.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
HEEBIOIH_01722 1.8e-226 ytcC M Glycosyltransferase Family 4
HEEBIOIH_01723 2.2e-176 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HEEBIOIH_01724 5.8e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEEBIOIH_01725 7.4e-152 galU 2.7.7.9 M Nucleotidyl transferase
HEEBIOIH_01726 9.7e-132 dksA T COG1734 DnaK suppressor protein
HEEBIOIH_01727 1.1e-269 menF 5.4.4.2 HQ Isochorismate synthase
HEEBIOIH_01728 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HEEBIOIH_01729 1.7e-151 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HEEBIOIH_01730 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEEBIOIH_01731 2.4e-270 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEEBIOIH_01732 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HEEBIOIH_01733 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
HEEBIOIH_01734 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEEBIOIH_01735 1.8e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEEBIOIH_01736 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HEEBIOIH_01737 4.3e-24 S Domain of Unknown Function (DUF1540)
HEEBIOIH_01738 5.2e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HEEBIOIH_01739 6.8e-248 cydA 1.10.3.14 C oxidase, subunit
HEEBIOIH_01740 6.1e-41 rpmE2 J Ribosomal protein L31
HEEBIOIH_01741 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HEEBIOIH_01742 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEEBIOIH_01743 1.1e-72 ytkA S YtkA-like
HEEBIOIH_01745 2.1e-76 dps P Belongs to the Dps family
HEEBIOIH_01746 1.7e-61 ytkC S Bacteriophage holin family
HEEBIOIH_01747 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HEEBIOIH_01748 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEEBIOIH_01749 1.4e-144 ytlC P ABC transporter
HEEBIOIH_01750 2.8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HEEBIOIH_01751 1.1e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HEEBIOIH_01752 4.7e-38 ytmB S Protein of unknown function (DUF2584)
HEEBIOIH_01753 2.8e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HEEBIOIH_01754 1.4e-223 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEEBIOIH_01755 0.0 asnB 6.3.5.4 E Asparagine synthase
HEEBIOIH_01756 1.7e-254 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HEEBIOIH_01757 2.7e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEEBIOIH_01758 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HEEBIOIH_01759 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HEEBIOIH_01760 7.4e-106 ytqB J Putative rRNA methylase
HEEBIOIH_01761 8.1e-190 yhcC S Fe-S oxidoreductase
HEEBIOIH_01762 1.5e-40 ytzC S Protein of unknown function (DUF2524)
HEEBIOIH_01764 5.1e-66 ytrA K GntR family transcriptional regulator
HEEBIOIH_01765 4.2e-161 ytrB P abc transporter atp-binding protein
HEEBIOIH_01766 2.1e-07 P ABC-2 family transporter protein
HEEBIOIH_01767 1.2e-116 P ABC-2 family transporter protein
HEEBIOIH_01768 1.7e-147
HEEBIOIH_01769 9.1e-127 ytrE V ABC transporter, ATP-binding protein
HEEBIOIH_01770 1.9e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HEEBIOIH_01771 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_01772 4.9e-182 T PhoQ Sensor
HEEBIOIH_01773 5.6e-138 bceA V ABC transporter, ATP-binding protein
HEEBIOIH_01774 2.5e-311 bceB V ABC transporter (permease)
HEEBIOIH_01775 1.1e-41 lysP E amino acid
HEEBIOIH_01776 1.2e-53 yqhL P COG0607 Rhodanese-related sulfurtransferase
HEEBIOIH_01777 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEEBIOIH_01778 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HEEBIOIH_01779 3.3e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEEBIOIH_01780 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEEBIOIH_01781 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HEEBIOIH_01782 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_01783 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HEEBIOIH_01784 4.1e-242 icd 1.1.1.42 C isocitrate
HEEBIOIH_01785 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HEEBIOIH_01786 4.7e-71 yeaL S membrane
HEEBIOIH_01787 5.8e-192 ytvI S sporulation integral membrane protein YtvI
HEEBIOIH_01788 3.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HEEBIOIH_01789 4.9e-311 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HEEBIOIH_01790 2.8e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEEBIOIH_01791 7.4e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HEEBIOIH_01792 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEEBIOIH_01793 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HEEBIOIH_01794 0.0 dnaE 2.7.7.7 L DNA polymerase
HEEBIOIH_01795 3.2e-56 ytrH S Sporulation protein YtrH
HEEBIOIH_01796 8.2e-69 ytrI
HEEBIOIH_01797 9.2e-29
HEEBIOIH_01798 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HEEBIOIH_01799 2.4e-47 ytpI S YtpI-like protein
HEEBIOIH_01800 2.3e-240 ytoI K transcriptional regulator containing CBS domains
HEEBIOIH_01801 2.3e-154 ytnM S membrane transporter protein
HEEBIOIH_01802 6.8e-186 ytnL 3.5.1.47 E hydrolase activity
HEEBIOIH_01803 1.4e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HEEBIOIH_01804 2e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEEBIOIH_01805 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
HEEBIOIH_01806 1.2e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEEBIOIH_01807 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEEBIOIH_01808 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
HEEBIOIH_01809 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
HEEBIOIH_01810 5.8e-149 tcyK M Bacterial periplasmic substrate-binding proteins
HEEBIOIH_01811 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
HEEBIOIH_01812 4.7e-99 ytmI K Acetyltransferase (GNAT) domain
HEEBIOIH_01813 2.9e-173 ytlI K LysR substrate binding domain
HEEBIOIH_01814 3.9e-130 ytkL S Belongs to the UPF0173 family
HEEBIOIH_01815 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEEBIOIH_01817 5.8e-266 argH 4.3.2.1 E argininosuccinate lyase
HEEBIOIH_01818 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEEBIOIH_01819 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HEEBIOIH_01820 4.1e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEEBIOIH_01821 3.3e-162 ytxK 2.1.1.72 L DNA methylase
HEEBIOIH_01822 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEEBIOIH_01823 1.5e-66 ytfJ S Sporulation protein YtfJ
HEEBIOIH_01824 9.6e-108 ytfI S Protein of unknown function (DUF2953)
HEEBIOIH_01825 1.5e-86 yteJ S RDD family
HEEBIOIH_01826 1.1e-178 sppA OU signal peptide peptidase SppA
HEEBIOIH_01827 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEEBIOIH_01828 0.0 ytcJ S amidohydrolase
HEEBIOIH_01829 1.2e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEEBIOIH_01830 2.2e-28 sspB S spore protein
HEEBIOIH_01831 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEEBIOIH_01832 9.2e-209 iscS2 2.8.1.7 E Cysteine desulfurase
HEEBIOIH_01833 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
HEEBIOIH_01834 4.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEEBIOIH_01835 6.6e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HEEBIOIH_01836 6.5e-108 yttP K Transcriptional regulator
HEEBIOIH_01837 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HEEBIOIH_01838 2.9e-76 ctsR K Belongs to the CtsR family
HEEBIOIH_01839 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HEEBIOIH_01840 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HEEBIOIH_01841 0.0 clpC O Belongs to the ClpA ClpB family
HEEBIOIH_01842 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEEBIOIH_01843 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HEEBIOIH_01844 1.7e-196 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HEEBIOIH_01845 4.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HEEBIOIH_01846 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HEEBIOIH_01847 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEEBIOIH_01848 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HEEBIOIH_01849 2.4e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HEEBIOIH_01850 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEEBIOIH_01851 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEEBIOIH_01852 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HEEBIOIH_01853 4.4e-115 sigH K Belongs to the sigma-70 factor family
HEEBIOIH_01854 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEEBIOIH_01855 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HEEBIOIH_01856 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEEBIOIH_01857 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEEBIOIH_01858 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEEBIOIH_01859 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEEBIOIH_01860 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HEEBIOIH_01861 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEEBIOIH_01862 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEEBIOIH_01863 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HEEBIOIH_01864 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEEBIOIH_01865 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEEBIOIH_01866 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEEBIOIH_01867 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEEBIOIH_01868 1.7e-184 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HEEBIOIH_01869 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HEEBIOIH_01870 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEEBIOIH_01871 3e-105 rplD J Forms part of the polypeptide exit tunnel
HEEBIOIH_01872 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEEBIOIH_01873 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEEBIOIH_01874 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEEBIOIH_01875 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEEBIOIH_01876 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEEBIOIH_01877 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEEBIOIH_01878 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HEEBIOIH_01879 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEEBIOIH_01880 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEEBIOIH_01881 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEEBIOIH_01882 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEEBIOIH_01883 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEEBIOIH_01884 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEEBIOIH_01885 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEEBIOIH_01886 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEEBIOIH_01887 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEEBIOIH_01888 1.9e-23 rpmD J Ribosomal protein L30
HEEBIOIH_01889 1.8e-72 rplO J binds to the 23S rRNA
HEEBIOIH_01890 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEEBIOIH_01891 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEEBIOIH_01892 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HEEBIOIH_01893 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEEBIOIH_01894 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HEEBIOIH_01895 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEEBIOIH_01896 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEEBIOIH_01897 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEEBIOIH_01898 3.6e-58 rplQ J Ribosomal protein L17
HEEBIOIH_01899 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEEBIOIH_01900 8.8e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEEBIOIH_01901 2.6e-117 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEEBIOIH_01902 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEEBIOIH_01903 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEEBIOIH_01904 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HEEBIOIH_01905 1.2e-143 ybaJ Q Methyltransferase domain
HEEBIOIH_01906 3.5e-71 ybaK S Protein of unknown function (DUF2521)
HEEBIOIH_01907 2.8e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEEBIOIH_01908 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HEEBIOIH_01909 1.2e-84 gerD
HEEBIOIH_01910 1.5e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HEEBIOIH_01911 3.5e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HEEBIOIH_01912 5.6e-134 M Membrane
HEEBIOIH_01913 2.4e-30 yetM CH FAD binding domain
HEEBIOIH_01914 9.1e-105 yetJ S Belongs to the BI1 family
HEEBIOIH_01915 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HEEBIOIH_01916 2.7e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEEBIOIH_01917 1.1e-33
HEEBIOIH_01918 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEEBIOIH_01919 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HEEBIOIH_01920 1.7e-120 yetF S membrane
HEEBIOIH_01921 4.6e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HEEBIOIH_01922 1.4e-161 lplC G Binding-protein-dependent transport system inner membrane component
HEEBIOIH_01923 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HEEBIOIH_01924 9e-289 lplA G Bacterial extracellular solute-binding protein
HEEBIOIH_01925 0.0 yetA
HEEBIOIH_01926 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HEEBIOIH_01927 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
HEEBIOIH_01928 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HEEBIOIH_01929 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HEEBIOIH_01930 2.4e-110 yesV S Protein of unknown function, DUF624
HEEBIOIH_01931 2.8e-125 yesU S Domain of unknown function (DUF1961)
HEEBIOIH_01932 9.7e-129 E GDSL-like Lipase/Acylhydrolase
HEEBIOIH_01933 0.0 yesS K Transcriptional regulator
HEEBIOIH_01934 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HEEBIOIH_01935 2.4e-89 yesQ P Binding-protein-dependent transport system inner membrane component
HEEBIOIH_01936 1.9e-60 yesQ P Binding-protein-dependent transport system inner membrane component
HEEBIOIH_01937 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
HEEBIOIH_01938 3.6e-246 yesO G Bacterial extracellular solute-binding protein
HEEBIOIH_01939 3.6e-73 yesN K helix_turn_helix, arabinose operon control protein
HEEBIOIH_01940 8.2e-114 yesN K helix_turn_helix, arabinose operon control protein
HEEBIOIH_01941 0.0 yesM 2.7.13.3 T Histidine kinase
HEEBIOIH_01942 5e-100 yesL S Protein of unknown function, DUF624
HEEBIOIH_01944 6e-102 yesJ K Acetyltransferase (GNAT) family
HEEBIOIH_01945 2e-103 cotJC P Spore Coat
HEEBIOIH_01946 5.6e-45 cotJB S CotJB protein
HEEBIOIH_01947 6.9e-45 cotJA S Spore coat associated protein JA (CotJA)
HEEBIOIH_01948 6.7e-99 dhaR3 K Transcriptional regulator
HEEBIOIH_01950 2.7e-126 yeeN K transcriptional regulatory protein
HEEBIOIH_01952 7.4e-211 S Tetratricopeptide repeat
HEEBIOIH_01953 3.6e-58 3.4.24.40 CO amine dehydrogenase activity
HEEBIOIH_01954 5.9e-96 3.4.24.40 CO amine dehydrogenase activity
HEEBIOIH_01955 0.0 L nucleic acid phosphodiester bond hydrolysis
HEEBIOIH_01956 2.7e-82 S Protein of unknown function, DUF600
HEEBIOIH_01958 2.6e-29 S Colicin immunity protein / pyocin immunity protein
HEEBIOIH_01960 3.7e-101 S response regulator aspartate phosphatase
HEEBIOIH_01962 1.9e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEEBIOIH_01963 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEEBIOIH_01964 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEEBIOIH_01965 7.4e-147 yerO K Transcriptional regulator
HEEBIOIH_01966 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEEBIOIH_01967 1e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEEBIOIH_01968 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEEBIOIH_01969 2.1e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEEBIOIH_01970 1.6e-123 sapB S MgtC SapB transporter
HEEBIOIH_01971 1.9e-194 yerI S homoserine kinase type II (protein kinase fold)
HEEBIOIH_01972 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEEBIOIH_01973 2.4e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HEEBIOIH_01974 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HEEBIOIH_01975 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HEEBIOIH_01976 1.2e-178 ykvI S membrane
HEEBIOIH_01977 0.0 clpE O Belongs to the ClpA ClpB family
HEEBIOIH_01978 5.1e-137 motA N flagellar motor
HEEBIOIH_01979 1.5e-122 motB N Flagellar motor protein
HEEBIOIH_01980 1.3e-75 ykvE K transcriptional
HEEBIOIH_01981 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HEEBIOIH_01982 1.1e-61 eag
HEEBIOIH_01983 6.4e-09 S Spo0E like sporulation regulatory protein
HEEBIOIH_01984 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HEEBIOIH_01985 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HEEBIOIH_01986 2.6e-112 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HEEBIOIH_01987 3.5e-134 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HEEBIOIH_01988 2.2e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HEEBIOIH_01989 3.4e-230 mtnE 2.6.1.83 E Aminotransferase
HEEBIOIH_01990 1.3e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEEBIOIH_01991 8.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HEEBIOIH_01992 4.8e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HEEBIOIH_01994 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEEBIOIH_01995 0.0 kinE 2.7.13.3 T Histidine kinase
HEEBIOIH_01996 1.6e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HEEBIOIH_01997 4.1e-18 ykzE
HEEBIOIH_01998 1.2e-10 ydfR S Protein of unknown function (DUF421)
HEEBIOIH_01999 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HEEBIOIH_02000 3.5e-155 htpX O Belongs to the peptidase M48B family
HEEBIOIH_02001 1.9e-124 ykrK S Domain of unknown function (DUF1836)
HEEBIOIH_02002 1.9e-26 sspD S small acid-soluble spore protein
HEEBIOIH_02003 7.2e-113 rsgI S Anti-sigma factor N-terminus
HEEBIOIH_02004 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEEBIOIH_02005 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HEEBIOIH_02006 2.7e-109 ykoX S membrane-associated protein
HEEBIOIH_02007 1.9e-64 ydcR 2.7.7.65 T Diguanylate cyclase
HEEBIOIH_02008 5.8e-62 ydcR 2.7.7.65 T Diguanylate cyclase
HEEBIOIH_02009 2.9e-108 ydcR 2.7.7.65 T Diguanylate cyclase
HEEBIOIH_02010 8.6e-27 ydcR 2.7.7.65 T Diguanylate cyclase
HEEBIOIH_02011 3.4e-58 ydcR 2.7.7.65 T Diguanylate cyclase
HEEBIOIH_02012 1.4e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HEEBIOIH_02013 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HEEBIOIH_02014 3.1e-184 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEEBIOIH_02015 0.0 ykoS
HEEBIOIH_02016 6e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HEEBIOIH_02017 6.3e-97 ykoP G polysaccharide deacetylase
HEEBIOIH_02018 3.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HEEBIOIH_02019 1.3e-81 mhqR K transcriptional
HEEBIOIH_02020 6.9e-26 ykoL
HEEBIOIH_02021 5.9e-18
HEEBIOIH_02022 1.4e-53 tnrA K transcriptional
HEEBIOIH_02023 2.2e-222 mgtE P Acts as a magnesium transporter
HEEBIOIH_02026 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
HEEBIOIH_02027 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
HEEBIOIH_02028 5.4e-240 ykoH 2.7.13.3 T Histidine kinase
HEEBIOIH_02029 6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_02030 7.4e-109 ykoF S YKOF-related Family
HEEBIOIH_02031 1.2e-98 ykoE S ABC-type cobalt transport system, permease component
HEEBIOIH_02032 5.7e-305 P ABC transporter, ATP-binding protein
HEEBIOIH_02033 7.6e-135 ykoC P Cobalt transport protein
HEEBIOIH_02034 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEEBIOIH_02035 1.5e-175 isp O Belongs to the peptidase S8 family
HEEBIOIH_02036 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEEBIOIH_02037 2.6e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEEBIOIH_02038 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
HEEBIOIH_02039 2.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HEEBIOIH_02040 4.4e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEEBIOIH_02041 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEEBIOIH_02042 4.5e-88 yaiI S Belongs to the UPF0178 family
HEEBIOIH_02043 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEEBIOIH_02044 4.5e-112 ccpN K CBS domain
HEEBIOIH_02045 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HEEBIOIH_02046 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HEEBIOIH_02047 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
HEEBIOIH_02048 8.4e-19 S YqzL-like protein
HEEBIOIH_02049 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEEBIOIH_02050 3.5e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEEBIOIH_02051 2.5e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HEEBIOIH_02052 8.8e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEEBIOIH_02053 0.0 yqfF S membrane-associated HD superfamily hydrolase
HEEBIOIH_02055 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HEEBIOIH_02056 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HEEBIOIH_02057 2.7e-45 yqfC S sporulation protein YqfC
HEEBIOIH_02058 6e-25 yqfB
HEEBIOIH_02059 4.3e-122 yqfA S UPF0365 protein
HEEBIOIH_02060 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HEEBIOIH_02061 2.5e-61 yqeY S Yqey-like protein
HEEBIOIH_02062 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HEEBIOIH_02063 7.3e-156 yqeW P COG1283 Na phosphate symporter
HEEBIOIH_02064 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HEEBIOIH_02065 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEEBIOIH_02066 5.4e-175 prmA J Methylates ribosomal protein L11
HEEBIOIH_02067 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEEBIOIH_02068 0.0 dnaK O Heat shock 70 kDa protein
HEEBIOIH_02069 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEEBIOIH_02070 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEEBIOIH_02071 1.7e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
HEEBIOIH_02072 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEEBIOIH_02073 7.2e-53 yqxA S Protein of unknown function (DUF3679)
HEEBIOIH_02074 1.5e-222 spoIIP M stage II sporulation protein P
HEEBIOIH_02075 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEEBIOIH_02076 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HEEBIOIH_02077 6.2e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
HEEBIOIH_02078 4.1e-15 S YqzM-like protein
HEEBIOIH_02079 0.0 comEC S Competence protein ComEC
HEEBIOIH_02080 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HEEBIOIH_02081 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HEEBIOIH_02082 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEEBIOIH_02083 1.4e-138 yqeM Q Methyltransferase
HEEBIOIH_02084 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEEBIOIH_02085 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HEEBIOIH_02086 3.8e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEEBIOIH_02087 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HEEBIOIH_02088 3.3e-155 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEEBIOIH_02089 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HEEBIOIH_02090 5.3e-95 yqeG S hydrolase of the HAD superfamily
HEEBIOIH_02092 1.4e-141 yqeF E GDSL-like Lipase/Acylhydrolase
HEEBIOIH_02093 7e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEEBIOIH_02094 8.8e-105 yqeD S SNARE associated Golgi protein
HEEBIOIH_02095 5e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HEEBIOIH_02096 6.3e-131 yqeB
HEEBIOIH_02097 1.6e-35 nucB M Deoxyribonuclease NucA/NucB
HEEBIOIH_02098 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEEBIOIH_02099 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HEEBIOIH_02100 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEEBIOIH_02101 4.1e-30 yazB K transcriptional
HEEBIOIH_02102 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEEBIOIH_02103 2.2e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEEBIOIH_02104 1.9e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEEBIOIH_02105 1.9e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HEEBIOIH_02106 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HEEBIOIH_02107 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEEBIOIH_02108 1.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HEEBIOIH_02109 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HEEBIOIH_02110 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEEBIOIH_02111 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEEBIOIH_02112 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEEBIOIH_02113 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HEEBIOIH_02114 3.2e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEEBIOIH_02115 3.7e-185 KLT serine threonine protein kinase
HEEBIOIH_02116 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HEEBIOIH_02117 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HEEBIOIH_02120 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HEEBIOIH_02121 1.1e-44 divIC D Septum formation initiator
HEEBIOIH_02122 4.3e-107 yabQ S spore cortex biosynthesis protein
HEEBIOIH_02123 1.5e-49 yabP S Sporulation protein YabP
HEEBIOIH_02124 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HEEBIOIH_02125 8.6e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HEEBIOIH_02126 7.8e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEEBIOIH_02127 1.5e-92 spoVT K stage V sporulation protein
HEEBIOIH_02128 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEEBIOIH_02129 2.4e-39 yabK S Peptide ABC transporter permease
HEEBIOIH_02130 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEEBIOIH_02131 4.3e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HEEBIOIH_02132 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEEBIOIH_02133 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEEBIOIH_02134 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HEEBIOIH_02135 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HEEBIOIH_02136 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HEEBIOIH_02137 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEEBIOIH_02138 2e-26 sspF S DNA topological change
HEEBIOIH_02139 7.8e-39 veg S protein conserved in bacteria
HEEBIOIH_02140 1.6e-136 yabG S peptidase
HEEBIOIH_02141 4.2e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEEBIOIH_02142 7.9e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEEBIOIH_02143 3.2e-165 rpfB GH23 T protein conserved in bacteria
HEEBIOIH_02144 1.7e-142 tatD L hydrolase, TatD
HEEBIOIH_02145 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEEBIOIH_02146 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HEEBIOIH_02147 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEEBIOIH_02148 1.5e-49 yazA L endonuclease containing a URI domain
HEEBIOIH_02149 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HEEBIOIH_02150 4.8e-31 yabA L Involved in initiation control of chromosome replication
HEEBIOIH_02151 6.1e-146 yaaT S stage 0 sporulation protein
HEEBIOIH_02152 1.1e-181 holB 2.7.7.7 L DNA polymerase III
HEEBIOIH_02153 1e-70 yaaR S protein conserved in bacteria
HEEBIOIH_02154 2.2e-54 yaaQ S protein conserved in bacteria
HEEBIOIH_02155 2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEEBIOIH_02156 4.8e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HEEBIOIH_02157 2.2e-202 yaaN P Belongs to the TelA family
HEEBIOIH_02158 2.6e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEEBIOIH_02159 3.4e-31 csfB S Inhibitor of sigma-G Gin
HEEBIOIH_02160 1.8e-09
HEEBIOIH_02161 2.5e-145 dnaG 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HEEBIOIH_02162 9.5e-59 L DNA primase activity
HEEBIOIH_02163 9.6e-122 recJ L Single-stranded-DNA-specific exonuclease RecJ
HEEBIOIH_02164 6.4e-20 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEEBIOIH_02165 6.1e-110 DR0488 S protein conserved in bacteria
HEEBIOIH_02170 4.1e-81 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
HEEBIOIH_02172 2.6e-163 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HEEBIOIH_02183 7.5e-77 yhdJ 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HEEBIOIH_02187 2.8e-64 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HEEBIOIH_02188 3.5e-113 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEEBIOIH_02189 1.7e-48 S HNH endonuclease
HEEBIOIH_02190 2.3e-226 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEEBIOIH_02191 2.2e-54 S Protein of unknown function (DUF1140)
HEEBIOIH_02192 1.7e-100 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEEBIOIH_02195 3.6e-30 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEEBIOIH_02196 1.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HEEBIOIH_02201 6.8e-161 S Thymidylate synthase
HEEBIOIH_02202 5.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEEBIOIH_02204 1.2e-35
HEEBIOIH_02206 1.6e-29 sspB S spore protein
HEEBIOIH_02210 9.7e-11 K Cro/C1-type HTH DNA-binding domain
HEEBIOIH_02211 2.3e-102 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEEBIOIH_02213 1.1e-62 4.2.1.115 GM Polysaccharide biosynthesis protein
HEEBIOIH_02214 6.4e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HEEBIOIH_02215 1.4e-186 cgeB S Spore maturation protein
HEEBIOIH_02216 4.8e-64 cgeA
HEEBIOIH_02217 5.9e-38 cgeC
HEEBIOIH_02218 8e-254 cgeD M maturation of the outermost layer of the spore
HEEBIOIH_02219 9.2e-144 yiiD K acetyltransferase
HEEBIOIH_02221 2.1e-238 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEEBIOIH_02222 2.4e-09 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEEBIOIH_02223 5.2e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEEBIOIH_02224 1.2e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
HEEBIOIH_02225 8.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HEEBIOIH_02226 1.4e-275 kamA 5.4.3.2 E lysine 2,3-aminomutase
HEEBIOIH_02227 2.9e-47 yokU S YokU-like protein, putative antitoxin
HEEBIOIH_02228 3.1e-36 yozE S Belongs to the UPF0346 family
HEEBIOIH_02229 6e-123 yodN
HEEBIOIH_02231 2.8e-24 yozD S YozD-like protein
HEEBIOIH_02232 6.6e-105 yodM 3.6.1.27 I Acid phosphatase homologues
HEEBIOIH_02233 7.9e-54 yodL S YodL-like
HEEBIOIH_02234 5.3e-09
HEEBIOIH_02235 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HEEBIOIH_02236 2.1e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HEEBIOIH_02237 2e-23 yodI
HEEBIOIH_02238 2.4e-127 yodH Q Methyltransferase
HEEBIOIH_02239 9.7e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HEEBIOIH_02240 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEEBIOIH_02241 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
HEEBIOIH_02242 2.7e-111 mhqD S Carboxylesterase
HEEBIOIH_02243 4.8e-12 S AAA domain
HEEBIOIH_02250 2.2e-154
HEEBIOIH_02252 3.2e-147 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HEEBIOIH_02259 5.4e-92 S Protein of unknown function (DUF1273)
HEEBIOIH_02263 2.9e-16 3.1.3.16, 3.1.4.37 T AAA domain
HEEBIOIH_02264 1.9e-53 S dUTPase
HEEBIOIH_02265 3.4e-22
HEEBIOIH_02269 1.1e-33 K Transcriptional regulator
HEEBIOIH_02270 2.1e-177
HEEBIOIH_02271 1.6e-260 S DNA-sulfur modification-associated
HEEBIOIH_02272 2.6e-197 L Belongs to the 'phage' integrase family
HEEBIOIH_02277 8.6e-106
HEEBIOIH_02279 5.8e-32 yoaF
HEEBIOIH_02280 7.7e-10
HEEBIOIH_02281 3.8e-36
HEEBIOIH_02282 2.1e-49 FG Scavenger mRNA decapping enzyme C-term binding
HEEBIOIH_02287 1.2e-95
HEEBIOIH_02290 1.7e-08
HEEBIOIH_02297 2e-198 3.1.21.3 L Domain of unknown function (DUF4942)
HEEBIOIH_02299 1.6e-235
HEEBIOIH_02302 0.0 S RNA-directed RNA polymerase activity
HEEBIOIH_02303 1.6e-14 L GIY-YIG type nucleases (URI domain)
HEEBIOIH_02304 2.6e-94
HEEBIOIH_02305 1.1e-33 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEEBIOIH_02307 2.1e-203 S Calcineurin-like phosphoesterase superfamily domain
HEEBIOIH_02311 2.2e-173
HEEBIOIH_02312 0.0 gp17a S Terminase-like family
HEEBIOIH_02313 2.7e-280
HEEBIOIH_02314 3.1e-254
HEEBIOIH_02315 7.8e-94
HEEBIOIH_02316 5.8e-87
HEEBIOIH_02317 3.8e-159 rlmA 2.1.1.187 Q Methyltransferase domain
HEEBIOIH_02318 9.8e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HEEBIOIH_02319 9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEEBIOIH_02320 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEEBIOIH_02321 4.8e-26 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEEBIOIH_02322 1.8e-90 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEEBIOIH_02323 8.2e-218 yxjG 2.1.1.14 E Methionine synthase
HEEBIOIH_02324 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
HEEBIOIH_02325 1.6e-85 yxjI S LURP-one-related
HEEBIOIH_02328 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HEEBIOIH_02329 7.1e-113 K helix_turn_helix, Lux Regulon
HEEBIOIH_02330 8.3e-192 yxjM T Signal transduction histidine kinase
HEEBIOIH_02331 1e-76 S Protein of unknown function (DUF1453)
HEEBIOIH_02332 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HEEBIOIH_02333 2.4e-73 yxkC S Domain of unknown function (DUF4352)
HEEBIOIH_02334 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEEBIOIH_02335 6.3e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEEBIOIH_02336 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HEEBIOIH_02337 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HEEBIOIH_02338 1.6e-154 yxkH G Polysaccharide deacetylase
HEEBIOIH_02340 3.3e-308 3.4.24.84 O Peptidase family M48
HEEBIOIH_02341 6.1e-228 cimH C COG3493 Na citrate symporter
HEEBIOIH_02342 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
HEEBIOIH_02343 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HEEBIOIH_02344 1.7e-310 cydD V ATP-binding
HEEBIOIH_02345 0.0 cydD V ATP-binding protein
HEEBIOIH_02346 2.5e-96 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEEBIOIH_02347 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HEEBIOIH_02348 1.4e-18 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HEEBIOIH_02349 2.5e-39 yxlC S Family of unknown function (DUF5345)
HEEBIOIH_02350 4.9e-28
HEEBIOIH_02351 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HEEBIOIH_02352 2.4e-147 yxlF V ABC transporter, ATP-binding protein
HEEBIOIH_02353 1.5e-98 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEEBIOIH_02354 2.5e-195 yxlH EGP Major facilitator Superfamily
HEEBIOIH_02355 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HEEBIOIH_02356 1.5e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HEEBIOIH_02357 1.1e-19 yxzF
HEEBIOIH_02358 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HEEBIOIH_02359 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HEEBIOIH_02360 9.9e-107 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEEBIOIH_02361 1.2e-123 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEEBIOIH_02362 5.6e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HEEBIOIH_02363 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEEBIOIH_02364 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HEEBIOIH_02365 6.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HEEBIOIH_02366 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEEBIOIH_02367 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEEBIOIH_02368 2.7e-232 dltB M membrane protein involved in D-alanine export
HEEBIOIH_02369 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEEBIOIH_02370 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HEEBIOIH_02371 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HEEBIOIH_02372 1e-130 ynfM EGP Major facilitator Superfamily
HEEBIOIH_02373 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
HEEBIOIH_02374 5.3e-92 K Helix-turn-helix XRE-family like proteins
HEEBIOIH_02375 8.3e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HEEBIOIH_02376 2.2e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEEBIOIH_02377 8.1e-88 ywaE K Transcriptional regulator
HEEBIOIH_02378 1.9e-64 ywaF S Integral membrane protein
HEEBIOIH_02379 1.2e-39 ywaF S Integral membrane protein
HEEBIOIH_02380 7e-169 gspA M General stress
HEEBIOIH_02381 4e-153 sacY K transcriptional antiterminator
HEEBIOIH_02382 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEEBIOIH_02383 2e-269 epr 3.4.21.62 O Belongs to the peptidase S8 family
HEEBIOIH_02384 1.8e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEEBIOIH_02385 2.3e-122 ywbB S Protein of unknown function (DUF2711)
HEEBIOIH_02386 4.4e-67 ywbC 4.4.1.5 E glyoxalase
HEEBIOIH_02387 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
HEEBIOIH_02388 1.2e-26 ywbE S Uncharacterized conserved protein (DUF2196)
HEEBIOIH_02389 2.2e-205 ywbF EGP Major facilitator Superfamily
HEEBIOIH_02390 2.3e-111 ywbG M effector of murein hydrolase
HEEBIOIH_02391 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HEEBIOIH_02392 4.3e-153 ywbI K Transcriptional regulator
HEEBIOIH_02393 3.4e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEEBIOIH_02394 3.6e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEEBIOIH_02395 1e-249 P COG0672 High-affinity Fe2 Pb2 permease
HEEBIOIH_02396 7.9e-184 ycdO P periplasmic lipoprotein involved in iron transport
HEEBIOIH_02397 1.6e-222 ywbN P Dyp-type peroxidase family protein
HEEBIOIH_02398 2.8e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HEEBIOIH_02399 1.5e-267 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEEBIOIH_02400 9.8e-49 ywcB S Protein of unknown function, DUF485
HEEBIOIH_02402 3.9e-119 ywcC K transcriptional regulator
HEEBIOIH_02403 9.5e-60 gtcA S GtrA-like protein
HEEBIOIH_02404 4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEEBIOIH_02405 3.3e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HEEBIOIH_02406 1e-35 ywzA S membrane
HEEBIOIH_02407 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HEEBIOIH_02408 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEEBIOIH_02409 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HEEBIOIH_02410 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HEEBIOIH_02411 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HEEBIOIH_02412 8.6e-202 rodA D Belongs to the SEDS family
HEEBIOIH_02413 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HEEBIOIH_02414 1.1e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEEBIOIH_02415 0.0 vpr O Belongs to the peptidase S8 family
HEEBIOIH_02418 1e-148 sacT K transcriptional antiterminator
HEEBIOIH_02419 3.3e-138 focA P Formate/nitrite transporter
HEEBIOIH_02420 1.9e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEEBIOIH_02421 2.1e-287 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HEEBIOIH_02422 2e-28 ywdA
HEEBIOIH_02423 3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HEEBIOIH_02424 6.3e-57 pex K Transcriptional regulator PadR-like family
HEEBIOIH_02425 7.5e-112 ywdD
HEEBIOIH_02427 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HEEBIOIH_02428 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEEBIOIH_02429 5e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HEEBIOIH_02430 7.7e-49 ywdI S Family of unknown function (DUF5327)
HEEBIOIH_02431 3.7e-238 ywdJ F Xanthine uracil
HEEBIOIH_02432 1.6e-58 ywdK S small membrane protein
HEEBIOIH_02433 8.3e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HEEBIOIH_02434 1.8e-144 spsA M Spore Coat
HEEBIOIH_02435 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
HEEBIOIH_02436 1.6e-221 spsC E Belongs to the DegT DnrJ EryC1 family
HEEBIOIH_02437 3.7e-162 spsD 2.3.1.210 K Spore Coat
HEEBIOIH_02438 2.1e-213 spsE 2.5.1.56 M acid synthase
HEEBIOIH_02439 1.3e-128 spsF M Spore Coat
HEEBIOIH_02440 2.3e-187 spsG M Spore Coat
HEEBIOIH_02441 3e-136 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEEBIOIH_02442 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEEBIOIH_02443 6.6e-69 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEEBIOIH_02444 2.9e-69 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEEBIOIH_02445 1.3e-86 spsL 5.1.3.13 M Spore Coat
HEEBIOIH_02446 1.2e-77
HEEBIOIH_02447 6.9e-206 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEEBIOIH_02448 1.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEEBIOIH_02449 0.0 rocB E arginine degradation protein
HEEBIOIH_02450 5.7e-261 lysP E amino acid
HEEBIOIH_02451 4.3e-204 ywfA EGP Major facilitator Superfamily
HEEBIOIH_02452 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HEEBIOIH_02453 1.2e-120 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HEEBIOIH_02454 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEEBIOIH_02455 2.3e-82 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HEEBIOIH_02456 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
HEEBIOIH_02457 3.3e-146 ywfI C May function as heme-dependent peroxidase
HEEBIOIH_02458 6.2e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HEEBIOIH_02459 7.1e-156 cysL K Transcriptional regulator
HEEBIOIH_02460 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HEEBIOIH_02461 1.7e-154 ywfM EG EamA-like transporter family
HEEBIOIH_02462 2.4e-107 rsfA_1
HEEBIOIH_02463 3.1e-36 ywzC S Belongs to the UPF0741 family
HEEBIOIH_02464 2.5e-255 ywfO S COG1078 HD superfamily phosphohydrolases
HEEBIOIH_02465 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
HEEBIOIH_02466 6.2e-79 yffB K Transcriptional regulator
HEEBIOIH_02467 1.6e-234 mmr U Major Facilitator Superfamily
HEEBIOIH_02469 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEEBIOIH_02470 3.3e-71 ywhA K Transcriptional regulator
HEEBIOIH_02471 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HEEBIOIH_02472 5.1e-119 ywhC S Peptidase family M50
HEEBIOIH_02473 2e-94 ywhD S YwhD family
HEEBIOIH_02474 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEEBIOIH_02475 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HEEBIOIH_02476 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HEEBIOIH_02477 7e-27 ywhH S Aminoacyl-tRNA editing domain
HEEBIOIH_02479 1.2e-78 S aspartate phosphatase
HEEBIOIH_02480 3.5e-79 ywhK CO amine dehydrogenase activity
HEEBIOIH_02481 4.5e-107 ywhK CO amine dehydrogenase activity
HEEBIOIH_02482 2.6e-55 ywhL CO amine dehydrogenase activity
HEEBIOIH_02483 6.3e-166 ywhL CO amine dehydrogenase activity
HEEBIOIH_02485 6.6e-248 L Peptidase, M16
HEEBIOIH_02486 1.4e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
HEEBIOIH_02487 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HEEBIOIH_02488 3.3e-132 cbiO V ABC transporter
HEEBIOIH_02490 4.9e-270 C Fe-S oxidoreductases
HEEBIOIH_02491 1e-07 S Bacteriocin subtilosin A
HEEBIOIH_02492 4.7e-73 ywiB S protein conserved in bacteria
HEEBIOIH_02493 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HEEBIOIH_02494 1e-213 narK P COG2223 Nitrate nitrite transporter
HEEBIOIH_02495 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HEEBIOIH_02496 1.1e-138 ywiC S YwiC-like protein
HEEBIOIH_02497 7e-86 arfM T cyclic nucleotide binding
HEEBIOIH_02498 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEEBIOIH_02499 4.3e-296 narH 1.7.5.1 C Nitrate reductase, beta
HEEBIOIH_02500 1.1e-93 narJ 1.7.5.1 C nitrate reductase
HEEBIOIH_02501 2.6e-123 narI 1.7.5.1 C nitrate reductase, gamma
HEEBIOIH_02502 7.9e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEEBIOIH_02503 0.0 ywjA V ABC transporter
HEEBIOIH_02504 5.9e-94 ywjB H RibD C-terminal domain
HEEBIOIH_02505 2.7e-42 ywjC
HEEBIOIH_02506 2.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HEEBIOIH_02507 3.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HEEBIOIH_02508 0.0 fadF C COG0247 Fe-S oxidoreductase
HEEBIOIH_02509 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HEEBIOIH_02510 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEEBIOIH_02511 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEEBIOIH_02512 1.3e-42 L Integrase core domain
HEEBIOIH_02513 2.5e-11 tnpIS3 L Transposase
HEEBIOIH_02514 1.3e-90 ywjG S Domain of unknown function (DUF2529)
HEEBIOIH_02515 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HEEBIOIH_02516 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HEEBIOIH_02517 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEEBIOIH_02518 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEEBIOIH_02519 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HEEBIOIH_02520 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEEBIOIH_02521 1.1e-32 rpmE J Binds the 23S rRNA
HEEBIOIH_02522 1.6e-103 tdk 2.7.1.21 F thymidine kinase
HEEBIOIH_02523 0.0 sfcA 1.1.1.38 C malic enzyme
HEEBIOIH_02524 8.6e-160 ywkB S Membrane transport protein
HEEBIOIH_02525 5.1e-88 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HEEBIOIH_02526 2.1e-64 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEEBIOIH_02527 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEEBIOIH_02528 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEEBIOIH_02530 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
HEEBIOIH_02531 6.1e-112 spoIIR S stage II sporulation protein R
HEEBIOIH_02532 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HEEBIOIH_02533 2.2e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEEBIOIH_02534 1.1e-90 mntP P Probably functions as a manganese efflux pump
HEEBIOIH_02535 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEEBIOIH_02536 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HEEBIOIH_02537 1.6e-94 ywlG S Belongs to the UPF0340 family
HEEBIOIH_02538 6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEEBIOIH_02539 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEEBIOIH_02540 2.5e-62 atpI S ATP synthase
HEEBIOIH_02541 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HEEBIOIH_02542 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEEBIOIH_02543 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEEBIOIH_02544 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEEBIOIH_02545 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEEBIOIH_02546 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEEBIOIH_02547 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEEBIOIH_02548 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HEEBIOIH_02549 4.8e-87 ywmA
HEEBIOIH_02550 1.3e-32 ywzB S membrane
HEEBIOIH_02551 3.4e-132 ywmB S TATA-box binding
HEEBIOIH_02552 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEEBIOIH_02553 9.8e-178 spoIID D Stage II sporulation protein D
HEEBIOIH_02554 3.3e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HEEBIOIH_02555 2.7e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HEEBIOIH_02557 2.9e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HEEBIOIH_02558 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEEBIOIH_02559 7.9e-104 S response regulator aspartate phosphatase
HEEBIOIH_02560 5.1e-84 ywmF S Peptidase M50
HEEBIOIH_02561 3.6e-09 csbD K CsbD-like
HEEBIOIH_02562 8.8e-221 urtA E Receptor family ligand binding region
HEEBIOIH_02563 4.6e-147 urtB E Belongs to the binding-protein-dependent transport system permease family
HEEBIOIH_02564 3.6e-183 urtC E Belongs to the binding-protein-dependent transport system permease family
HEEBIOIH_02565 1.4e-120 urtD S ATPases associated with a variety of cellular activities
HEEBIOIH_02566 4.4e-113 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HEEBIOIH_02567 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HEEBIOIH_02568 1.6e-61 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HEEBIOIH_02569 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HEEBIOIH_02570 1.7e-64 ywnA K Transcriptional regulator
HEEBIOIH_02571 4.2e-110 ywnB S NAD(P)H-binding
HEEBIOIH_02572 1.7e-58 ywnC S Family of unknown function (DUF5362)
HEEBIOIH_02573 5.9e-143 mta K transcriptional
HEEBIOIH_02574 2.7e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEEBIOIH_02575 3.2e-69 ywnF S Family of unknown function (DUF5392)
HEEBIOIH_02576 1.4e-07 ywnC S Family of unknown function (DUF5362)
HEEBIOIH_02577 2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HEEBIOIH_02578 2e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HEEBIOIH_02579 2.3e-72 ywnJ S VanZ like family
HEEBIOIH_02580 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HEEBIOIH_02581 1.6e-58 nrgB K Belongs to the P(II) protein family
HEEBIOIH_02582 2.5e-225 amt P Ammonium transporter
HEEBIOIH_02583 2.2e-76
HEEBIOIH_02584 1.2e-103 phzA Q Isochorismatase family
HEEBIOIH_02585 1.6e-239 ywoD EGP Major facilitator superfamily
HEEBIOIH_02586 9.8e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HEEBIOIH_02587 1.5e-224 ywoF P Right handed beta helix region
HEEBIOIH_02588 4.6e-211 ywoG EGP Major facilitator Superfamily
HEEBIOIH_02589 4.7e-70 ywoH K COG1846 Transcriptional regulators
HEEBIOIH_02590 3e-44 spoIIID K Stage III sporulation protein D
HEEBIOIH_02591 3.5e-180 mbl D Rod shape-determining protein
HEEBIOIH_02592 6.9e-126 flhO N flagellar basal body
HEEBIOIH_02593 2.6e-141 flhP N flagellar basal body
HEEBIOIH_02594 2.3e-198 S aspartate phosphatase
HEEBIOIH_02595 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEEBIOIH_02596 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEEBIOIH_02597 1.2e-152 ywpD T Histidine kinase
HEEBIOIH_02598 2.6e-49 srtA 3.4.22.70 M Sortase family
HEEBIOIH_02599 6.9e-66 ywpF S YwpF-like protein
HEEBIOIH_02600 1.2e-29 ywpG
HEEBIOIH_02601 9.8e-58 ssbB L Single-stranded DNA-binding protein
HEEBIOIH_02602 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HEEBIOIH_02603 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HEEBIOIH_02604 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEEBIOIH_02605 7.8e-307 ywqB S SWIM zinc finger
HEEBIOIH_02606 1.2e-17
HEEBIOIH_02607 5.9e-116 ywqC M biosynthesis protein
HEEBIOIH_02608 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HEEBIOIH_02609 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HEEBIOIH_02610 1.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEEBIOIH_02611 5.4e-152 ywqG S Domain of unknown function (DUF1963)
HEEBIOIH_02612 1.3e-19 S Domain of unknown function (DUF5082)
HEEBIOIH_02613 1.2e-37 ywqI S Family of unknown function (DUF5344)
HEEBIOIH_02614 3.3e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
HEEBIOIH_02615 7.9e-43
HEEBIOIH_02616 5.2e-17
HEEBIOIH_02617 1.6e-81 ywqJ S Pre-toxin TG
HEEBIOIH_02618 3.9e-25
HEEBIOIH_02619 3e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HEEBIOIH_02620 1.4e-161 K Transcriptional regulator
HEEBIOIH_02621 1.1e-100 ywqN S NAD(P)H-dependent
HEEBIOIH_02623 2.2e-88 ywrA P COG2059 Chromate transport protein ChrA
HEEBIOIH_02624 1.2e-103 ywrB P Chromate transporter
HEEBIOIH_02625 8e-82 ywrC K Transcriptional regulator
HEEBIOIH_02626 1.1e-300 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HEEBIOIH_02627 2.7e-52 S Domain of unknown function (DUF4181)
HEEBIOIH_02628 9.9e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HEEBIOIH_02629 1.1e-12
HEEBIOIH_02630 2.4e-206 cotH M Spore Coat
HEEBIOIH_02631 1.4e-23 cotB
HEEBIOIH_02632 8.8e-77 cotB
HEEBIOIH_02633 1.4e-124 ywrJ
HEEBIOIH_02634 2.4e-179 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEEBIOIH_02635 1.1e-169 alsR K LysR substrate binding domain
HEEBIOIH_02636 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HEEBIOIH_02637 1.4e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HEEBIOIH_02638 6.3e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HEEBIOIH_02639 8e-48 ywsA S Protein of unknown function (DUF3892)
HEEBIOIH_02640 1.2e-91 batE T Sh3 type 3 domain protein
HEEBIOIH_02641 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HEEBIOIH_02642 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HEEBIOIH_02643 4e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HEEBIOIH_02644 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEEBIOIH_02645 2.5e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEEBIOIH_02646 5.5e-178 rbsR K transcriptional
HEEBIOIH_02647 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HEEBIOIH_02648 8.6e-70 pgsC S biosynthesis protein
HEEBIOIH_02649 9.1e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HEEBIOIH_02650 3.6e-21 ywtC
HEEBIOIH_02651 4.9e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEEBIOIH_02652 3.3e-113 tetR3 K Transcriptional regulator
HEEBIOIH_02653 1.9e-118 mepA V Multidrug transporter MatE
HEEBIOIH_02654 5.3e-70 mepA V Multidrug transporter MatE
HEEBIOIH_02655 6e-165 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HEEBIOIH_02656 2.1e-111 yrkJ S membrane transporter protein
HEEBIOIH_02657 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HEEBIOIH_02658 9.3e-206 yrkH P Rhodanese Homology Domain
HEEBIOIH_02659 4.7e-16 perX S Sulfur reduction protein DsrE
HEEBIOIH_02660 4.2e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
HEEBIOIH_02661 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
HEEBIOIH_02662 7.8e-39 yrkD S protein conserved in bacteria
HEEBIOIH_02663 8.6e-21
HEEBIOIH_02664 1.8e-104 yrkC G Cupin domain
HEEBIOIH_02665 3.1e-150 bltR K helix_turn_helix, mercury resistance
HEEBIOIH_02666 3.5e-211 blt EGP Major facilitator Superfamily
HEEBIOIH_02667 1.5e-82 bltD 2.3.1.57 K FR47-like protein
HEEBIOIH_02668 1.1e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HEEBIOIH_02669 3.9e-16 S YrzO-like protein
HEEBIOIH_02670 1.9e-170 yrdR EG EamA-like transporter family
HEEBIOIH_02671 6.6e-159 yrdQ K Transcriptional regulator
HEEBIOIH_02672 3.6e-196 trkA P Oxidoreductase
HEEBIOIH_02673 2.6e-153 czcD P COG1230 Co Zn Cd efflux system component
HEEBIOIH_02674 4.2e-65 yodA S tautomerase
HEEBIOIH_02675 5e-162 gltR K LysR substrate binding domain
HEEBIOIH_02676 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
HEEBIOIH_02677 5.6e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HEEBIOIH_02678 2.2e-91 azlC E AzlC protein
HEEBIOIH_02679 1.1e-78 bkdR K helix_turn_helix ASNC type
HEEBIOIH_02680 9.7e-40 yrdF K ribonuclease inhibitor
HEEBIOIH_02681 2.1e-227 cypA C Cytochrome P450
HEEBIOIH_02682 4.2e-23 K Acetyltransferase (GNAT) family
HEEBIOIH_02683 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
HEEBIOIH_02684 1.9e-57 S Protein of unknown function (DUF2568)
HEEBIOIH_02686 6.4e-90 yrdA S DinB family
HEEBIOIH_02687 5.1e-164 aadK G Streptomycin adenylyltransferase
HEEBIOIH_02688 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HEEBIOIH_02689 3.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HEEBIOIH_02690 4.8e-123 yrpD S Domain of unknown function, YrpD
HEEBIOIH_02692 1.3e-113 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HEEBIOIH_02693 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HEEBIOIH_02694 1.7e-187 yrpG C Aldo/keto reductase family
HEEBIOIH_02695 2e-08 yrpG C Aldo/keto reductase family
HEEBIOIH_02696 9.5e-226 yraO C Citrate transporter
HEEBIOIH_02697 3.4e-163 yraN K Transcriptional regulator
HEEBIOIH_02698 5.9e-205 yraM S PrpF protein
HEEBIOIH_02699 2.3e-14 yraM S PrpF protein
HEEBIOIH_02700 1.1e-14 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HEEBIOIH_02701 3.2e-37 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEEBIOIH_02702 4.7e-151 S Alpha beta hydrolase
HEEBIOIH_02703 1.7e-60 T sh3 domain protein
HEEBIOIH_02704 3.4e-61 T sh3 domain protein
HEEBIOIH_02705 1.4e-65 E Glyoxalase-like domain
HEEBIOIH_02706 1.5e-36 yraG
HEEBIOIH_02707 1.9e-62 yraF M Spore coat protein
HEEBIOIH_02708 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEEBIOIH_02709 7.5e-26 yraE
HEEBIOIH_02710 1.2e-12 yraD M Spore coat protein
HEEBIOIH_02712 1.4e-34 ydjO S Cold-inducible protein YdjO
HEEBIOIH_02713 8.4e-156 ydjP I Alpha/beta hydrolase family
HEEBIOIH_02714 6.7e-176 yeaA S Protein of unknown function (DUF4003)
HEEBIOIH_02715 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HEEBIOIH_02716 9.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HEEBIOIH_02717 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEEBIOIH_02718 9.5e-175 yeaC S COG0714 MoxR-like ATPases
HEEBIOIH_02719 2.9e-221 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HEEBIOIH_02720 0.0 yebA E COG1305 Transglutaminase-like enzymes
HEEBIOIH_02721 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HEEBIOIH_02722 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
HEEBIOIH_02723 9.8e-256 S Domain of unknown function (DUF4179)
HEEBIOIH_02724 1.5e-210 pbuG S permease
HEEBIOIH_02725 1.9e-115 yebC M Membrane
HEEBIOIH_02727 4e-93 yebE S UPF0316 protein
HEEBIOIH_02728 8e-28 yebG S NETI protein
HEEBIOIH_02729 7.4e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEEBIOIH_02730 1.6e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEEBIOIH_02731 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEEBIOIH_02732 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HEEBIOIH_02733 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEEBIOIH_02734 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEEBIOIH_02735 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEEBIOIH_02736 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEEBIOIH_02737 7.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HEEBIOIH_02738 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEEBIOIH_02739 1.7e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HEEBIOIH_02740 4.5e-233 purD 6.3.4.13 F Belongs to the GARS family
HEEBIOIH_02741 8.2e-70 K helix_turn_helix ASNC type
HEEBIOIH_02742 3.5e-225 yjeH E Amino acid permease
HEEBIOIH_02743 2.7e-27 S Protein of unknown function (DUF2892)
HEEBIOIH_02744 0.0 yerA 3.5.4.2 F adenine deaminase
HEEBIOIH_02745 2e-188 yerB S Protein of unknown function (DUF3048) C-terminal domain
HEEBIOIH_02746 4.8e-51 yerC S protein conserved in bacteria
HEEBIOIH_02747 5.7e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HEEBIOIH_02748 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HEEBIOIH_02749 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HEEBIOIH_02750 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEEBIOIH_02751 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HEEBIOIH_02752 2.4e-60 ykzC S Acetyltransferase (GNAT) family
HEEBIOIH_02753 8.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
HEEBIOIH_02754 7.1e-26 ykzI
HEEBIOIH_02755 2.1e-117 yktB S Belongs to the UPF0637 family
HEEBIOIH_02756 1.6e-42 yktA S Belongs to the UPF0223 family
HEEBIOIH_02757 1e-276 speA 4.1.1.19 E Arginine
HEEBIOIH_02758 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HEEBIOIH_02759 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEEBIOIH_02760 2.4e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEEBIOIH_02761 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEEBIOIH_02762 2.2e-191 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEEBIOIH_02763 2e-115 recN L Putative cell-wall binding lipoprotein
HEEBIOIH_02765 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEEBIOIH_02766 1e-145 ykrA S hydrolases of the HAD superfamily
HEEBIOIH_02767 8.2e-31 ykzG S Belongs to the UPF0356 family
HEEBIOIH_02768 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEEBIOIH_02769 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEEBIOIH_02770 1.5e-115 ktrA P COG0569 K transport systems, NAD-binding component
HEEBIOIH_02771 1.2e-154 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HEEBIOIH_02772 1.3e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HEEBIOIH_02773 1.5e-43 abrB K of stationary sporulation gene expression
HEEBIOIH_02774 7.7e-183 mreB D Rod-share determining protein MreBH
HEEBIOIH_02775 1.1e-12 S Uncharacterized protein YkpC
HEEBIOIH_02776 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HEEBIOIH_02777 2e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEEBIOIH_02778 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEEBIOIH_02779 1.1e-38 ykoA
HEEBIOIH_02780 2.4e-104 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HEEBIOIH_02781 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HEEBIOIH_02782 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HEEBIOIH_02783 3.1e-136 fruR K Transcriptional regulator
HEEBIOIH_02784 8.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HEEBIOIH_02785 7.2e-124 macB V ABC transporter, ATP-binding protein
HEEBIOIH_02786 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEEBIOIH_02787 1e-117 yknW S Yip1 domain
HEEBIOIH_02788 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEEBIOIH_02789 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEEBIOIH_02790 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HEEBIOIH_02791 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HEEBIOIH_02792 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HEEBIOIH_02793 5.2e-245 moeA 2.10.1.1 H molybdopterin
HEEBIOIH_02794 2.2e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEEBIOIH_02795 2.5e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEEBIOIH_02796 1.2e-145 yknT
HEEBIOIH_02797 4.8e-108 yodC C nitroreductase
HEEBIOIH_02798 4.4e-55 yodB K transcriptional
HEEBIOIH_02799 1.4e-63 yodA S tautomerase
HEEBIOIH_02800 1.2e-204 gntP EG COG2610 H gluconate symporter and related permeases
HEEBIOIH_02801 2e-09
HEEBIOIH_02802 1.5e-64 yozR S COG0071 Molecular chaperone (small heat shock protein)
HEEBIOIH_02803 1.2e-160 rarD S -transporter
HEEBIOIH_02804 1.5e-43
HEEBIOIH_02805 2.2e-60 yojF S Protein of unknown function (DUF1806)
HEEBIOIH_02806 2.1e-125 yojG S deacetylase
HEEBIOIH_02807 1.6e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEEBIOIH_02808 2.2e-241 norM V Multidrug efflux pump
HEEBIOIH_02810 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEEBIOIH_02811 1e-229 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HEEBIOIH_02812 6.2e-195 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HEEBIOIH_02813 5.6e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEEBIOIH_02814 2.5e-161 yojN S ATPase family associated with various cellular activities (AAA)
HEEBIOIH_02815 0.0 yojO P Von Willebrand factor
HEEBIOIH_02816 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HEEBIOIH_02817 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HEEBIOIH_02818 8.6e-168 yocS S -transporter
HEEBIOIH_02819 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEEBIOIH_02820 2.3e-164 sodA 1.15.1.1 P Superoxide dismutase
HEEBIOIH_02821 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HEEBIOIH_02822 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HEEBIOIH_02823 2.7e-31 yozC
HEEBIOIH_02824 4.2e-56 yozO S Bacterial PH domain
HEEBIOIH_02825 1.9e-36 yocN
HEEBIOIH_02826 1.1e-40 yozN
HEEBIOIH_02827 5.9e-85 yocM O Belongs to the small heat shock protein (HSP20) family
HEEBIOIH_02828 1.7e-29
HEEBIOIH_02829 8.4e-54 yocL
HEEBIOIH_02830 3.3e-83 dksA T general stress protein
HEEBIOIH_02831 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEEBIOIH_02832 0.0 recQ 3.6.4.12 L DNA helicase
HEEBIOIH_02833 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HEEBIOIH_02834 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEEBIOIH_02835 1.7e-196 desK 2.7.13.3 T Histidine kinase
HEEBIOIH_02836 5.3e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HEEBIOIH_02837 1.8e-184 yocD 3.4.17.13 V peptidase S66
HEEBIOIH_02838 1.5e-91 yocC
HEEBIOIH_02839 5.1e-142
HEEBIOIH_02840 1.5e-92 yozB S membrane
HEEBIOIH_02842 7.2e-152 ydjN U Involved in the tonB-independent uptake of proteins
HEEBIOIH_02843 4.5e-64 ydjM M Lytic transglycolase
HEEBIOIH_02844 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HEEBIOIH_02845 5e-257 iolT EGP Major facilitator Superfamily
HEEBIOIH_02846 5.3e-27 S Ion transport 2 domain protein
HEEBIOIH_02847 4.9e-145 S Ion transport 2 domain protein
HEEBIOIH_02848 8.5e-147 ydjI S virion core protein (lumpy skin disease virus)
HEEBIOIH_02849 2.5e-130 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HEEBIOIH_02850 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEEBIOIH_02851 1.9e-113 pspA KT Phage shock protein A
HEEBIOIH_02852 1.8e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HEEBIOIH_02853 2.1e-252 gutA G MFS/sugar transport protein
HEEBIOIH_02854 1.5e-200 gutB 1.1.1.14 E Dehydrogenase
HEEBIOIH_02855 0.0 K NB-ARC domain
HEEBIOIH_02856 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HEEBIOIH_02857 3.2e-100 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HEEBIOIH_02858 5.2e-287 hsdM 2.1.1.72 V Type I restriction-modification system
HEEBIOIH_02859 3.1e-80 3.1.21.3 V Type I restriction modification DNA specificity domain
HEEBIOIH_02860 5.1e-64 yozB S Membrane
HEEBIOIH_02863 6.1e-98 M nucleic acid phosphodiester bond hydrolysis
HEEBIOIH_02864 1e-151 yobL S Bacterial EndoU nuclease
HEEBIOIH_02865 4.1e-40
HEEBIOIH_02867 8.3e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEEBIOIH_02868 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEEBIOIH_02869 7.9e-129 ydiL S CAAX protease self-immunity
HEEBIOIH_02870 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HEEBIOIH_02871 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEEBIOIH_02872 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEEBIOIH_02873 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEEBIOIH_02874 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEEBIOIH_02875 0.0 ydiF S ABC transporter
HEEBIOIH_02876 3e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEEBIOIH_02877 2.8e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEEBIOIH_02878 1.1e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HEEBIOIH_02879 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HEEBIOIH_02880 1.2e-180 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEEBIOIH_02882 7.8e-08
HEEBIOIH_02883 5.8e-95 rok K Repressor of ComK
HEEBIOIH_02884 1.4e-80 ykuV CO thiol-disulfide
HEEBIOIH_02885 1.1e-100 ykuU O Alkyl hydroperoxide reductase
HEEBIOIH_02886 8.8e-142 ykuT M Mechanosensitive ion channel
HEEBIOIH_02887 9e-37 ykuS S Belongs to the UPF0180 family
HEEBIOIH_02888 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEEBIOIH_02889 2.4e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEEBIOIH_02890 5.1e-78 fld C Flavodoxin
HEEBIOIH_02891 9.7e-174 ykuO
HEEBIOIH_02892 1e-84 fld C Flavodoxin domain
HEEBIOIH_02893 3.5e-168 ccpC K Transcriptional regulator
HEEBIOIH_02894 1.6e-76 ykuL S CBS domain
HEEBIOIH_02895 3.9e-27 ykzF S Antirepressor AbbA
HEEBIOIH_02896 1.3e-93 ykuK S Ribonuclease H-like
HEEBIOIH_02897 3.9e-37 ykuJ S protein conserved in bacteria
HEEBIOIH_02899 3.3e-233 ykuI T Diguanylate phosphodiesterase
HEEBIOIH_02901 0.0 3.2.1.132 M Putative peptidoglycan binding domain
HEEBIOIH_02902 6.4e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEEBIOIH_02903 1.6e-165 ykuE S Metallophosphoesterase
HEEBIOIH_02904 1.5e-86 ykuD S protein conserved in bacteria
HEEBIOIH_02905 4.8e-238 ykuC EGP Major facilitator Superfamily
HEEBIOIH_02906 1.7e-84 ykyB S YkyB-like protein
HEEBIOIH_02907 2.4e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
HEEBIOIH_02908 2.2e-15
HEEBIOIH_02909 3.7e-221 patA 2.6.1.1 E Aminotransferase
HEEBIOIH_02910 0.0 pilS 2.7.13.3 T Histidine kinase
HEEBIOIH_02911 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HEEBIOIH_02912 7.5e-108 ykwD J protein with SCP PR1 domains
HEEBIOIH_02913 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HEEBIOIH_02914 4.4e-259 mcpC NT chemotaxis protein
HEEBIOIH_02915 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEEBIOIH_02916 1.4e-200 splB 4.1.99.14 L Spore photoproduct lyase
HEEBIOIH_02917 7.2e-39 splA S Transcriptional regulator
HEEBIOIH_02918 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEEBIOIH_02919 2.1e-39 ptsH G phosphocarrier protein HPr
HEEBIOIH_02920 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEEBIOIH_02921 7.6e-128 glcT K antiterminator
HEEBIOIH_02923 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
HEEBIOIH_02924 1.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HEEBIOIH_02925 2.3e-09
HEEBIOIH_02926 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HEEBIOIH_02927 1.6e-88 stoA CO thiol-disulfide
HEEBIOIH_02928 2.2e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEEBIOIH_02929 4.8e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
HEEBIOIH_02930 2.8e-28
HEEBIOIH_02931 6e-25 ykvS S protein conserved in bacteria
HEEBIOIH_02932 2.8e-45 ykvR S Protein of unknown function (DUF3219)
HEEBIOIH_02933 9.7e-34 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEEBIOIH_02934 1.5e-89 L Belongs to the 'phage' integrase family
HEEBIOIH_02935 2.4e-41
HEEBIOIH_02936 1.2e-247 I Pfam Lipase (class 3)
HEEBIOIH_02937 3e-28 S Protein of unknown function (DUF1433)
HEEBIOIH_02938 7.1e-46 S Protein of unknown function (DUF1433)
HEEBIOIH_02939 6.9e-90
HEEBIOIH_02940 1.1e-80
HEEBIOIH_02941 3.2e-68
HEEBIOIH_02943 1.4e-121
HEEBIOIH_02944 1.7e-77
HEEBIOIH_02945 2.3e-72
HEEBIOIH_02946 3.2e-59
HEEBIOIH_02949 1.2e-45
HEEBIOIH_02950 9.5e-18
HEEBIOIH_02951 5.9e-11
HEEBIOIH_02952 5.4e-08 S Phage uncharacterised protein (Phage_XkdX)
HEEBIOIH_02953 3.3e-99 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
HEEBIOIH_02954 5.9e-56
HEEBIOIH_02955 1.2e-52
HEEBIOIH_02956 8.3e-190 xerH A Belongs to the 'phage' integrase family
HEEBIOIH_02958 5.4e-46
HEEBIOIH_02959 0.0 S peptidoglycan catabolic process
HEEBIOIH_02960 8.5e-86 S Phage tail protein
HEEBIOIH_02961 1.6e-293 S Pfam Transposase IS66
HEEBIOIH_02962 3.7e-119
HEEBIOIH_02963 2.8e-20 M Pectate lyase superfamily protein
HEEBIOIH_02964 1.5e-209 yfmO EGP Major facilitator Superfamily
HEEBIOIH_02965 1.4e-69 yfmP K transcriptional
HEEBIOIH_02966 2e-74 yfmQ S Uncharacterised protein from bacillus cereus group
HEEBIOIH_02967 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEEBIOIH_02968 4.6e-112 yfmS NT chemotaxis protein
HEEBIOIH_02969 2.6e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEEBIOIH_02970 2.4e-240 yfnA E amino acid
HEEBIOIH_02971 6.2e-90 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HEEBIOIH_02972 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
HEEBIOIH_02973 2.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
HEEBIOIH_02974 2.6e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HEEBIOIH_02975 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
HEEBIOIH_02976 1.9e-172 yfnG 4.2.1.45 M dehydratase
HEEBIOIH_02977 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
HEEBIOIH_02978 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HEEBIOIH_02979 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HEEBIOIH_02980 2.4e-195 yetN S Protein of unknown function (DUF3900)
HEEBIOIH_02981 9.2e-92 batE T Bacterial SH3 domain homologues
HEEBIOIH_02982 3.9e-50 yfhL S SdpI/YhfL protein family
HEEBIOIH_02983 1.3e-170 yfhM S Alpha beta hydrolase
HEEBIOIH_02984 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEEBIOIH_02985 0.0 yfhO S Bacterial membrane protein YfhO
HEEBIOIH_02986 2.1e-185 yfhP S membrane-bound metal-dependent
HEEBIOIH_02987 2.5e-210 mutY L A G-specific
HEEBIOIH_02988 6.9e-36 yfhS
HEEBIOIH_02989 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEEBIOIH_02990 5.3e-08 sspE S Small, acid-soluble spore protein, gamma-type
HEEBIOIH_02991 4.9e-48 ygaB S YgaB-like protein
HEEBIOIH_02992 1.3e-104 ygaC J Belongs to the UPF0374 family
HEEBIOIH_02993 1.8e-301 ygaD V ABC transporter
HEEBIOIH_02994 3.6e-178 ygaE S Membrane
HEEBIOIH_02995 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HEEBIOIH_02996 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
HEEBIOIH_02997 4e-80 perR P Belongs to the Fur family
HEEBIOIH_02998 9.5e-56 ygzB S UPF0295 protein
HEEBIOIH_02999 2.5e-166 ygxA S Nucleotidyltransferase-like
HEEBIOIH_03000 8.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HEEBIOIH_03001 0.0 ylaA
HEEBIOIH_03002 3e-41 ylaB
HEEBIOIH_03003 1.3e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HEEBIOIH_03004 7e-12 sigC S Putative zinc-finger
HEEBIOIH_03005 4.1e-38 ylaE
HEEBIOIH_03006 8.2e-22 S Family of unknown function (DUF5325)
HEEBIOIH_03007 0.0 typA T GTP-binding protein TypA
HEEBIOIH_03008 4.2e-47 ylaH S YlaH-like protein
HEEBIOIH_03009 2.5e-32 ylaI S protein conserved in bacteria
HEEBIOIH_03010 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEEBIOIH_03011 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HEEBIOIH_03012 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEEBIOIH_03013 1.4e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
HEEBIOIH_03014 8.7e-44 ylaN S Belongs to the UPF0358 family
HEEBIOIH_03015 1.5e-209 ftsW D Belongs to the SEDS family
HEEBIOIH_03016 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEEBIOIH_03017 2.2e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HEEBIOIH_03018 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEEBIOIH_03019 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HEEBIOIH_03020 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEEBIOIH_03021 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HEEBIOIH_03022 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HEEBIOIH_03023 7e-164 ctaG S cytochrome c oxidase
HEEBIOIH_03024 7.7e-61 ylbA S YugN-like family
HEEBIOIH_03025 5.7e-74 ylbB T COG0517 FOG CBS domain
HEEBIOIH_03026 7.4e-200 ylbC S protein with SCP PR1 domains
HEEBIOIH_03027 4.1e-63 ylbD S Putative coat protein
HEEBIOIH_03028 6.7e-37 ylbE S YlbE-like protein
HEEBIOIH_03029 1.8e-75 ylbF S Belongs to the UPF0342 family
HEEBIOIH_03030 3.7e-38 ylbG S UPF0298 protein
HEEBIOIH_03031 2.5e-95 rsmD 2.1.1.171 L Methyltransferase
HEEBIOIH_03032 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEEBIOIH_03033 3.2e-220 ylbJ S Sporulation integral membrane protein YlbJ
HEEBIOIH_03034 6.4e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
HEEBIOIH_03035 2.6e-186 ylbL T Belongs to the peptidase S16 family
HEEBIOIH_03036 2.8e-235 ylbM S Belongs to the UPF0348 family
HEEBIOIH_03038 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HEEBIOIH_03039 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HEEBIOIH_03040 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HEEBIOIH_03041 1.5e-88 ylbP K n-acetyltransferase
HEEBIOIH_03042 2.9e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEEBIOIH_03043 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HEEBIOIH_03044 2.9e-78 mraZ K Belongs to the MraZ family
HEEBIOIH_03045 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEEBIOIH_03046 3.7e-44 ftsL D Essential cell division protein
HEEBIOIH_03047 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HEEBIOIH_03048 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HEEBIOIH_03049 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEEBIOIH_03050 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEEBIOIH_03051 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEEBIOIH_03052 5.7e-186 spoVE D Belongs to the SEDS family
HEEBIOIH_03053 9.7e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEEBIOIH_03054 5.3e-167 murB 1.3.1.98 M cell wall formation
HEEBIOIH_03055 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEEBIOIH_03056 5.4e-103 ylxW S protein conserved in bacteria
HEEBIOIH_03057 3.1e-116 ylxX S protein conserved in bacteria
HEEBIOIH_03058 1.4e-57 sbp S small basic protein
HEEBIOIH_03059 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEEBIOIH_03060 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEEBIOIH_03061 0.0 bpr O COG1404 Subtilisin-like serine proteases
HEEBIOIH_03062 1.6e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HEEBIOIH_03063 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEEBIOIH_03064 6.8e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEEBIOIH_03065 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HEEBIOIH_03066 2.2e-251 argE 3.5.1.16 E Acetylornithine deacetylase
HEEBIOIH_03067 2.4e-37 ylmC S sporulation protein
HEEBIOIH_03068 1.7e-156 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HEEBIOIH_03069 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEEBIOIH_03070 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEEBIOIH_03071 1.3e-39 yggT S membrane
HEEBIOIH_03072 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HEEBIOIH_03073 2.6e-67 divIVA D Cell division initiation protein
HEEBIOIH_03074 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEEBIOIH_03075 1.3e-63 dksA T COG1734 DnaK suppressor protein
HEEBIOIH_03076 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEEBIOIH_03077 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEEBIOIH_03078 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEEBIOIH_03079 2.6e-231 pyrP F Xanthine uracil
HEEBIOIH_03080 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HEEBIOIH_03081 3.5e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEEBIOIH_03082 1.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HEEBIOIH_03083 0.0 carB 6.3.5.5 F Belongs to the CarB family
HEEBIOIH_03084 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HEEBIOIH_03085 2.7e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEEBIOIH_03086 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEEBIOIH_03087 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEEBIOIH_03088 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HEEBIOIH_03089 1.4e-179 cysP P phosphate transporter
HEEBIOIH_03090 4.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HEEBIOIH_03091 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HEEBIOIH_03092 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HEEBIOIH_03093 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HEEBIOIH_03094 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HEEBIOIH_03095 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HEEBIOIH_03096 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HEEBIOIH_03097 2.4e-156 yloC S stress-induced protein
HEEBIOIH_03098 6e-17 ylzA S Belongs to the UPF0296 family
HEEBIOIH_03099 3.8e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HEEBIOIH_03100 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEEBIOIH_03101 1.6e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEEBIOIH_03102 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEEBIOIH_03103 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEEBIOIH_03104 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEEBIOIH_03105 9.3e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEEBIOIH_03106 4.1e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEEBIOIH_03107 1.6e-140 stp 3.1.3.16 T phosphatase
HEEBIOIH_03108 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HEEBIOIH_03109 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEEBIOIH_03110 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HEEBIOIH_03111 2e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
HEEBIOIH_03112 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HEEBIOIH_03113 5.5e-59 asp S protein conserved in bacteria
HEEBIOIH_03114 1.6e-299 yloV S kinase related to dihydroxyacetone kinase
HEEBIOIH_03115 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HEEBIOIH_03116 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HEEBIOIH_03117 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEEBIOIH_03118 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HEEBIOIH_03119 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEEBIOIH_03120 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HEEBIOIH_03121 6.1e-129 IQ reductase
HEEBIOIH_03122 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEEBIOIH_03123 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEEBIOIH_03124 0.0 smc D Required for chromosome condensation and partitioning
HEEBIOIH_03125 1.3e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEEBIOIH_03126 3.2e-125 S Phosphotransferase enzyme family
HEEBIOIH_03127 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEEBIOIH_03128 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEEBIOIH_03129 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HEEBIOIH_03130 4.5e-36 ylqC S Belongs to the UPF0109 family
HEEBIOIH_03131 1.4e-60 ylqD S YlqD protein
HEEBIOIH_03132 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEEBIOIH_03133 1.3e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HEEBIOIH_03134 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEEBIOIH_03135 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEEBIOIH_03136 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEEBIOIH_03137 2.7e-289 ylqG
HEEBIOIH_03138 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HEEBIOIH_03139 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HEEBIOIH_03140 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEEBIOIH_03141 8e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HEEBIOIH_03142 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEEBIOIH_03143 3.7e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEEBIOIH_03144 2.5e-169 xerC L tyrosine recombinase XerC
HEEBIOIH_03145 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEEBIOIH_03146 2.2e-249 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEEBIOIH_03147 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HEEBIOIH_03148 3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HEEBIOIH_03149 7.6e-74 flgC N Belongs to the flagella basal body rod proteins family
HEEBIOIH_03150 1.9e-31 fliE N Flagellar hook-basal body
HEEBIOIH_03151 9.1e-255 fliF N The M ring may be actively involved in energy transduction
HEEBIOIH_03152 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEEBIOIH_03153 9.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HEEBIOIH_03154 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HEEBIOIH_03155 4.2e-69 fliJ N Flagellar biosynthesis chaperone
HEEBIOIH_03156 3.8e-36 ylxF S MgtE intracellular N domain
HEEBIOIH_03157 2.3e-220 fliK N Flagellar hook-length control protein
HEEBIOIH_03158 8.7e-72 flgD N Flagellar basal body rod modification protein
HEEBIOIH_03159 1.3e-137 flgG N Flagellar basal body rod
HEEBIOIH_03160 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HEEBIOIH_03161 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEEBIOIH_03162 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEEBIOIH_03163 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HEEBIOIH_03164 6e-96 fliZ N Flagellar biosynthesis protein, FliO
HEEBIOIH_03165 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HEEBIOIH_03166 6.4e-36 fliQ N Role in flagellar biosynthesis
HEEBIOIH_03167 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HEEBIOIH_03168 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEEBIOIH_03169 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEEBIOIH_03170 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
HEEBIOIH_03171 4.1e-156 flhG D Belongs to the ParA family
HEEBIOIH_03172 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HEEBIOIH_03173 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HEEBIOIH_03174 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HEEBIOIH_03175 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HEEBIOIH_03176 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HEEBIOIH_03177 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEEBIOIH_03178 3.1e-76 ylxL
HEEBIOIH_03179 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HEEBIOIH_03180 8.2e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEEBIOIH_03181 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HEEBIOIH_03182 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEEBIOIH_03183 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEEBIOIH_03184 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HEEBIOIH_03185 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HEEBIOIH_03186 7.7e-233 rasP M zinc metalloprotease
HEEBIOIH_03187 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEEBIOIH_03188 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEEBIOIH_03189 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HEEBIOIH_03190 1.1e-203 nusA K Participates in both transcription termination and antitermination
HEEBIOIH_03191 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HEEBIOIH_03192 3.1e-47 ylxQ J ribosomal protein
HEEBIOIH_03193 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEEBIOIH_03194 5e-44 ylxP S protein conserved in bacteria
HEEBIOIH_03195 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEEBIOIH_03196 7.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEEBIOIH_03197 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HEEBIOIH_03198 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEEBIOIH_03199 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEEBIOIH_03200 2.2e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HEEBIOIH_03201 4.4e-233 pepR S Belongs to the peptidase M16 family
HEEBIOIH_03202 2.6e-42 ymxH S YlmC YmxH family
HEEBIOIH_03203 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HEEBIOIH_03204 1.4e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HEEBIOIH_03205 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEEBIOIH_03206 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HEEBIOIH_03207 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEEBIOIH_03208 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEEBIOIH_03209 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HEEBIOIH_03210 4.4e-32 S YlzJ-like protein
HEEBIOIH_03211 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HEEBIOIH_03212 1.4e-133 ymfC K Transcriptional regulator
HEEBIOIH_03213 3.8e-205 ymfD EGP Major facilitator Superfamily
HEEBIOIH_03214 3.9e-232 ymfF S Peptidase M16
HEEBIOIH_03215 1.4e-242 ymfH S zinc protease
HEEBIOIH_03216 5e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HEEBIOIH_03217 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HEEBIOIH_03218 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HEEBIOIH_03219 2.1e-115 ymfM S protein conserved in bacteria
HEEBIOIH_03220 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEEBIOIH_03221 8.1e-235 cinA 3.5.1.42 S Belongs to the CinA family
HEEBIOIH_03222 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEEBIOIH_03223 1.7e-213 pbpX V Beta-lactamase
HEEBIOIH_03224 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HEEBIOIH_03225 1.9e-152 ymdB S protein conserved in bacteria
HEEBIOIH_03226 1.2e-36 spoVS S Stage V sporulation protein S
HEEBIOIH_03227 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HEEBIOIH_03228 2.5e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEEBIOIH_03229 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEEBIOIH_03230 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HEEBIOIH_03231 2.2e-88 cotE S Spore coat protein
HEEBIOIH_03232 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEEBIOIH_03233 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEEBIOIH_03234 2.2e-68 S Regulatory protein YrvL
HEEBIOIH_03235 1.1e-95 ymcC S Membrane
HEEBIOIH_03236 1.2e-103 pksA K Transcriptional regulator
HEEBIOIH_03237 4.4e-61 ymzB
HEEBIOIH_03238 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
HEEBIOIH_03239 1.2e-249 aprX O Belongs to the peptidase S8 family
HEEBIOIH_03240 1.9e-07 K Transcriptional regulator
HEEBIOIH_03241 2.1e-126 ymaC S Replication protein
HEEBIOIH_03242 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
HEEBIOIH_03243 6.2e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HEEBIOIH_03244 4.9e-51 ebrA P Small Multidrug Resistance protein
HEEBIOIH_03246 2.1e-46 ymaF S YmaF family
HEEBIOIH_03247 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEEBIOIH_03248 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HEEBIOIH_03249 8.2e-23
HEEBIOIH_03250 4.5e-22 ymzA
HEEBIOIH_03251 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HEEBIOIH_03252 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEEBIOIH_03253 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEEBIOIH_03254 2e-109 ymaB
HEEBIOIH_03255 2.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEEBIOIH_03256 1.7e-176 spoVK O stage V sporulation protein K
HEEBIOIH_03257 4.7e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEEBIOIH_03258 9.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HEEBIOIH_03259 1.1e-68 glnR K transcriptional
HEEBIOIH_03260 1e-259 glnA 6.3.1.2 E glutamine synthetase
HEEBIOIH_03263 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HEEBIOIH_03264 4.9e-12
HEEBIOIH_03265 1.1e-127 yydK K Transcriptional regulator
HEEBIOIH_03266 3.7e-32 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HEEBIOIH_03267 3e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEEBIOIH_03268 2.5e-286 ahpF O Alkyl hydroperoxide reductase
HEEBIOIH_03269 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HEEBIOIH_03270 2.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEEBIOIH_03271 5.9e-231 gntP EG COG2610 H gluconate symporter and related permeases
HEEBIOIH_03272 1.2e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HEEBIOIH_03273 7.3e-127 gntR K transcriptional
HEEBIOIH_03274 1.2e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HEEBIOIH_03275 7.4e-186 yxaB GM Polysaccharide pyruvyl transferase
HEEBIOIH_03276 1.4e-107 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HEEBIOIH_03277 2.2e-80 yokK S SMI1 / KNR4 family
HEEBIOIH_03278 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
HEEBIOIH_03279 3.8e-291 UW nuclease activity
HEEBIOIH_03280 1.1e-101 yokH G SMI1 / KNR4 family
HEEBIOIH_03281 1.1e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HEEBIOIH_03282 1e-198 yobO M Pectate lyase superfamily protein
HEEBIOIH_03283 2.4e-221 yobO M Pectate lyase superfamily protein
HEEBIOIH_03284 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HEEBIOIH_03285 1.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
HEEBIOIH_03286 8.5e-139 yobR 2.3.1.1 J FR47-like protein
HEEBIOIH_03287 2.8e-97 yobS K Transcriptional regulator
HEEBIOIH_03288 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HEEBIOIH_03289 3.1e-86 yobU K Bacterial transcription activator, effector binding domain
HEEBIOIH_03290 2.7e-174 yobV K WYL domain
HEEBIOIH_03291 2.6e-92 yobW
HEEBIOIH_03292 1e-51 czrA K transcriptional
HEEBIOIH_03293 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEEBIOIH_03294 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HEEBIOIH_03295 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HEEBIOIH_03296 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEEBIOIH_03297 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEEBIOIH_03298 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEEBIOIH_03299 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEEBIOIH_03300 1.4e-95 yaaI Q COG1335 Amidases related to nicotinamidase
HEEBIOIH_03301 5.1e-208 yaaH M Glycoside Hydrolase Family
HEEBIOIH_03302 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HEEBIOIH_03303 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HEEBIOIH_03304 1.3e-09
HEEBIOIH_03305 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEEBIOIH_03306 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HEEBIOIH_03307 2.8e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HEEBIOIH_03308 7.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HEEBIOIH_03309 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEEBIOIH_03310 3.8e-179 yaaC S YaaC-like Protein
HEEBIOIH_03311 2.4e-29 KLT Protein tyrosine kinase
HEEBIOIH_03312 4.3e-11 S YolD-like protein
HEEBIOIH_03313 1.9e-36
HEEBIOIH_03314 9e-19
HEEBIOIH_03315 5.1e-18
HEEBIOIH_03316 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
HEEBIOIH_03317 9.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
HEEBIOIH_03319 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HEEBIOIH_03320 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HEEBIOIH_03321 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HEEBIOIH_03322 4.8e-51 yjdF S Protein of unknown function (DUF2992)
HEEBIOIH_03323 5.9e-97 S Protein of unknown function (DUF421)
HEEBIOIH_03324 2.1e-282 clsA_1 I PLD-like domain
HEEBIOIH_03325 1.2e-70 S Protein of unknown function (DUF421)
HEEBIOIH_03326 2.8e-07 S Protein of unknown function (DUF421)
HEEBIOIH_03327 1.2e-149 yetF1 S membrane
HEEBIOIH_03328 5.8e-29 S Protein of unknown function (DUF1657)
HEEBIOIH_03329 2.5e-56 spoVAE S stage V sporulation protein
HEEBIOIH_03330 1e-195 spoVAD I Stage V sporulation protein AD
HEEBIOIH_03331 2.6e-80 spoVAC S stage V sporulation protein AC
HEEBIOIH_03332 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEEBIOIH_03333 6e-26 S Protein of unknown function (DUF1657)
HEEBIOIH_03334 1.1e-23 cat P Catalase
HEEBIOIH_03335 2.1e-91 cat P Catalase
HEEBIOIH_03336 5.3e-67 S TIGRFAM germination protein, Ger(x)C family
HEEBIOIH_03337 3.6e-99 EG Spore germination protein
HEEBIOIH_03338 2.2e-91 yuaB
HEEBIOIH_03339 5.5e-95 yuaC K Belongs to the GbsR family
HEEBIOIH_03340 1.2e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HEEBIOIH_03341 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HEEBIOIH_03342 4.8e-105 yuaD
HEEBIOIH_03343 3.3e-83 yuaE S DinB superfamily
HEEBIOIH_03344 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HEEBIOIH_03345 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
HEEBIOIH_03346 3.4e-94 M1-753 M FR47-like protein
HEEBIOIH_03347 5.7e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HEEBIOIH_03349 3.6e-66 K Transcriptional regulator
HEEBIOIH_03350 8e-218 pre D plasmid recombination enzyme
HEEBIOIH_03351 1.3e-21
HEEBIOIH_03353 3.8e-42
HEEBIOIH_03354 1.4e-195 L Replication protein
HEEBIOIH_03355 5.5e-97 S Tetratricopeptide repeat
HEEBIOIH_03356 2.3e-254 xynT G MFS/sugar transport protein
HEEBIOIH_03357 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HEEBIOIH_03358 2.3e-212 xylR GK ROK family
HEEBIOIH_03359 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HEEBIOIH_03360 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HEEBIOIH_03361 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HEEBIOIH_03362 2.5e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEEBIOIH_03363 2.8e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEEBIOIH_03364 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEEBIOIH_03365 3.4e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEEBIOIH_03366 4.5e-24 yqzJ
HEEBIOIH_03367 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEEBIOIH_03368 4.7e-132 yqjF S Uncharacterized conserved protein (COG2071)
HEEBIOIH_03369 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HEEBIOIH_03371 2.8e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEEBIOIH_03372 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HEEBIOIH_03373 4.2e-29 S Domain of unknown function (DUF4177)
HEEBIOIH_03374 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEEBIOIH_03375 3.6e-82 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HEEBIOIH_03376 5e-142 spo0M S COG4326 Sporulation control protein
HEEBIOIH_03377 1.2e-26
HEEBIOIH_03378 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HEEBIOIH_03379 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEEBIOIH_03380 7.6e-263 ygaK C Berberine and berberine like
HEEBIOIH_03382 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HEEBIOIH_03383 8.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HEEBIOIH_03384 7.3e-170 ssuA M Sulfonate ABC transporter
HEEBIOIH_03385 1.1e-37 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEEBIOIH_03386 1.3e-96 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEEBIOIH_03387 2.6e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HEEBIOIH_03389 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEEBIOIH_03390 1.3e-76 ygaO
HEEBIOIH_03391 4.4e-29 K Transcriptional regulator
HEEBIOIH_03393 7.9e-114 yhzB S B3/4 domain
HEEBIOIH_03394 5.1e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEEBIOIH_03395 3.5e-174 yhbB S Putative amidase domain
HEEBIOIH_03396 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEEBIOIH_03397 1.4e-102 yhbD K Protein of unknown function (DUF4004)
HEEBIOIH_03398 2.7e-57 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HEEBIOIH_03399 0.0 prkA T Ser protein kinase
HEEBIOIH_03400 2.5e-225 yhbH S Belongs to the UPF0229 family
HEEBIOIH_03401 2.2e-76 yhbI K DNA-binding transcription factor activity
HEEBIOIH_03402 3.8e-87 yhbJ V COG1566 Multidrug resistance efflux pump
HEEBIOIH_03403 6.9e-271 yhcA EGP Major facilitator Superfamily
HEEBIOIH_03404 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HEEBIOIH_03405 2.8e-37 yhcC
HEEBIOIH_03406 3.6e-52
HEEBIOIH_03407 1.6e-58 yhcF K Transcriptional regulator
HEEBIOIH_03408 8.8e-122 yhcG V ABC transporter, ATP-binding protein
HEEBIOIH_03409 7.2e-164 yhcH V ABC transporter, ATP-binding protein
HEEBIOIH_03410 2.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEEBIOIH_03411 1e-30 cspB K Cold-shock protein
HEEBIOIH_03412 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
HEEBIOIH_03413 8.4e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HEEBIOIH_03414 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEEBIOIH_03415 4.9e-41 yhcM
HEEBIOIH_03416 2.1e-61 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEEBIOIH_03417 1e-158 yhcP
HEEBIOIH_03418 1.6e-96 yhcQ M Spore coat protein
HEEBIOIH_03419 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HEEBIOIH_03420 1.1e-101 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HEEBIOIH_03421 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HEEBIOIH_03422 9.3e-68 yhcU S Family of unknown function (DUF5365)
HEEBIOIH_03423 3.8e-67 yhcV S COG0517 FOG CBS domain
HEEBIOIH_03424 1e-119 yhcW 5.4.2.6 S hydrolase
HEEBIOIH_03425 2.3e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEEBIOIH_03426 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEEBIOIH_03427 3.4e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HEEBIOIH_03428 1.4e-150 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HEEBIOIH_03429 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEEBIOIH_03430 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEEBIOIH_03431 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HEEBIOIH_03432 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
HEEBIOIH_03433 2e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEEBIOIH_03434 1.2e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
HEEBIOIH_03435 1.2e-38 yhdB S YhdB-like protein
HEEBIOIH_03436 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HEEBIOIH_03437 1e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HEEBIOIH_03438 1e-75 nsrR K Transcriptional regulator
HEEBIOIH_03439 9.6e-238 ygxB M Conserved TM helix
HEEBIOIH_03440 2e-261 ycgB S Stage V sporulation protein R
HEEBIOIH_03441 3.2e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HEEBIOIH_03442 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HEEBIOIH_03443 3.8e-162 citR K Transcriptional regulator
HEEBIOIH_03444 1.3e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
HEEBIOIH_03445 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEEBIOIH_03446 3.4e-250 yhdG E amino acid
HEEBIOIH_03447 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEEBIOIH_03448 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEEBIOIH_03449 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEEBIOIH_03450 8.1e-45 yhdK S Sigma-M inhibitor protein
HEEBIOIH_03451 6.6e-201 yhdL S Sigma factor regulator N-terminal
HEEBIOIH_03452 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HEEBIOIH_03453 5.7e-191 yhdN C Aldo keto reductase
HEEBIOIH_03454 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEEBIOIH_03455 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HEEBIOIH_03456 8e-74 cueR K transcriptional
HEEBIOIH_03457 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
HEEBIOIH_03458 1.8e-238 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HEEBIOIH_03459 1.1e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEEBIOIH_03460 6.2e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEEBIOIH_03461 6.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEEBIOIH_03463 5.6e-203 yhdY M Mechanosensitive ion channel
HEEBIOIH_03464 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HEEBIOIH_03465 3.9e-148 yheN G deacetylase
HEEBIOIH_03466 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HEEBIOIH_03467 1.2e-231 nhaC C Na H antiporter
HEEBIOIH_03468 3.1e-84 nhaX T Belongs to the universal stress protein A family
HEEBIOIH_03469 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEEBIOIH_03470 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HEEBIOIH_03471 2.9e-108 yheG GM NAD(P)H-binding
HEEBIOIH_03472 6.3e-28 sspB S spore protein
HEEBIOIH_03473 1.3e-36 yheE S Family of unknown function (DUF5342)
HEEBIOIH_03474 1.1e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HEEBIOIH_03475 4.3e-216 yheC HJ YheC/D like ATP-grasp
HEEBIOIH_03476 6.3e-202 yheB S Belongs to the UPF0754 family
HEEBIOIH_03477 9.5e-48 yheA S Belongs to the UPF0342 family
HEEBIOIH_03478 1.2e-131 yhaZ L DNA alkylation repair enzyme
HEEBIOIH_03479 3.1e-53 yhaZ L DNA alkylation repair enzyme
HEEBIOIH_03480 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HEEBIOIH_03481 1e-292 hemZ H coproporphyrinogen III oxidase
HEEBIOIH_03482 1.8e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
HEEBIOIH_03483 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HEEBIOIH_03485 2.3e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
HEEBIOIH_03486 2.4e-26 S YhzD-like protein
HEEBIOIH_03487 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HEEBIOIH_03488 1e-213 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HEEBIOIH_03489 2.2e-221 yhaO L DNA repair exonuclease
HEEBIOIH_03490 0.0 yhaN L AAA domain
HEEBIOIH_03491 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HEEBIOIH_03492 1.6e-21 yhaL S Sporulation protein YhaL
HEEBIOIH_03493 1.8e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEEBIOIH_03494 8.7e-90 yhaK S Putative zincin peptidase
HEEBIOIH_03495 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HEEBIOIH_03496 1e-113 hpr K Negative regulator of protease production and sporulation
HEEBIOIH_03497 7e-39 yhaH S YtxH-like protein
HEEBIOIH_03498 3.6e-80 trpP S Tryptophan transporter TrpP
HEEBIOIH_03499 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEEBIOIH_03500 1.1e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HEEBIOIH_03501 4.6e-137 ecsA V transporter (ATP-binding protein)
HEEBIOIH_03502 1.6e-214 ecsB U ABC transporter
HEEBIOIH_03503 1.4e-114 ecsC S EcsC protein family
HEEBIOIH_03504 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HEEBIOIH_03505 1.9e-245 yhfA C membrane
HEEBIOIH_03506 1.9e-34 1.15.1.2 C Rubrerythrin
HEEBIOIH_03507 8.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HEEBIOIH_03508 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HEEBIOIH_03509 6.3e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HEEBIOIH_03510 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HEEBIOIH_03511 1.2e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HEEBIOIH_03512 4.6e-100 yhgD K Transcriptional regulator
HEEBIOIH_03513 1.7e-214 yhgE S YhgE Pip N-terminal domain protein
HEEBIOIH_03514 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEEBIOIH_03515 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
HEEBIOIH_03516 6.6e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HEEBIOIH_03517 3.7e-72 3.4.13.21 S ASCH
HEEBIOIH_03518 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEEBIOIH_03519 3.4e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HEEBIOIH_03520 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HEEBIOIH_03521 2.9e-111 yhfK GM NmrA-like family
HEEBIOIH_03522 3.1e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HEEBIOIH_03523 1.4e-63 yhfM
HEEBIOIH_03524 2.5e-239 yhfN 3.4.24.84 O Peptidase M48
HEEBIOIH_03525 2e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HEEBIOIH_03526 6.2e-76 VY92_01935 K acetyltransferase
HEEBIOIH_03527 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HEEBIOIH_03528 2.5e-154 yfmC M Periplasmic binding protein
HEEBIOIH_03529 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HEEBIOIH_03530 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
HEEBIOIH_03531 9e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HEEBIOIH_03532 5e-91 bioY S BioY family
HEEBIOIH_03533 5.4e-181 hemAT NT chemotaxis protein
HEEBIOIH_03534 7.4e-97 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HEEBIOIH_03535 1.6e-188 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HEEBIOIH_03536 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEEBIOIH_03537 1.3e-32 yhzC S IDEAL
HEEBIOIH_03538 4.2e-109 comK K Competence transcription factor
HEEBIOIH_03539 2.9e-165 IQ Enoyl-(Acyl carrier protein) reductase
HEEBIOIH_03540 1.1e-40 yhjA S Excalibur calcium-binding domain
HEEBIOIH_03541 2.3e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEEBIOIH_03542 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HEEBIOIH_03543 6.7e-60 yhjD
HEEBIOIH_03544 9.1e-110 yhjE S SNARE associated Golgi protein
HEEBIOIH_03545 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HEEBIOIH_03546 7.3e-283 yhjG CH FAD binding domain
HEEBIOIH_03547 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HEEBIOIH_03548 7.6e-214 glcP G Major Facilitator Superfamily
HEEBIOIH_03549 1.3e-198 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HEEBIOIH_03550 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HEEBIOIH_03551 1.9e-112 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HEEBIOIH_03552 3.8e-128 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HEEBIOIH_03553 5.9e-188 yhjM 5.1.1.1 K Transcriptional regulator
HEEBIOIH_03554 1.9e-201 abrB S membrane
HEEBIOIH_03555 2.2e-213 EGP Transmembrane secretion effector
HEEBIOIH_03556 0.0 S Sugar transport-related sRNA regulator N-term
HEEBIOIH_03557 2.2e-78 yhjR S Rubrerythrin
HEEBIOIH_03558 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HEEBIOIH_03559 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HEEBIOIH_03560 9.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEEBIOIH_03561 0.0 sbcC L COG0419 ATPase involved in DNA repair
HEEBIOIH_03562 3.1e-47 yisB V COG1403 Restriction endonuclease
HEEBIOIH_03563 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HEEBIOIH_03564 3e-66 gerPE S Spore germination protein GerPE
HEEBIOIH_03565 6.3e-24 gerPD S Spore germination protein
HEEBIOIH_03566 5.3e-54 gerPC S Spore germination protein
HEEBIOIH_03567 4e-34 gerPB S cell differentiation
HEEBIOIH_03568 1.9e-33 gerPA S Spore germination protein
HEEBIOIH_03569 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HEEBIOIH_03570 2.7e-174 cotH M Spore Coat
HEEBIOIH_03571 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HEEBIOIH_03572 3e-57 yisL S UPF0344 protein
HEEBIOIH_03573 0.0 wprA O Belongs to the peptidase S8 family
HEEBIOIH_03574 4e-101 yisN S Protein of unknown function (DUF2777)
HEEBIOIH_03575 0.0 asnO 6.3.5.4 E Asparagine synthase
HEEBIOIH_03576 1.1e-118 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HEEBIOIH_03577 1.5e-242 yisQ V Mate efflux family protein
HEEBIOIH_03578 3.5e-160 yisR K Transcriptional regulator
HEEBIOIH_03579 5.5e-181 purR K helix_turn _helix lactose operon repressor
HEEBIOIH_03580 4.4e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HEEBIOIH_03581 7e-92 yisT S DinB family
HEEBIOIH_03582 1.2e-106 argO S Lysine exporter protein LysE YggA
HEEBIOIH_03583 7.6e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEEBIOIH_03584 2e-35 mcbG S Pentapeptide repeats (9 copies)
HEEBIOIH_03585 1.3e-153 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEEBIOIH_03586 6e-111 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HEEBIOIH_03587 4.3e-163 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HEEBIOIH_03588 5.4e-52 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HEEBIOIH_03589 1.5e-57 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HEEBIOIH_03590 2.7e-62 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HEEBIOIH_03591 2.5e-121 comB 3.1.3.71 H Belongs to the ComB family
HEEBIOIH_03592 3.5e-140 yitD 4.4.1.19 S synthase
HEEBIOIH_03593 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEEBIOIH_03594 1e-144 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HEEBIOIH_03595 3.4e-39 S COG NOG14552 non supervised orthologous group
HEEBIOIH_03596 9.3e-48 S SMI1-KNR4 cell-wall
HEEBIOIH_03597 1.8e-206 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEEBIOIH_03598 3.5e-42 S Putative amidase domain
HEEBIOIH_03600 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HEEBIOIH_03601 0.0 rocB E arginine degradation protein
HEEBIOIH_03602 7.3e-68
HEEBIOIH_03603 6.1e-153 M Pectate lyase superfamily protein
HEEBIOIH_03604 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEEBIOIH_03605 1.1e-306 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HEEBIOIH_03606 2.2e-12 K Helix-turn-helix XRE-family like proteins
HEEBIOIH_03607 1.9e-44 M D-alanyl-D-alanine carboxypeptidase
HEEBIOIH_03611 2.8e-54 ynaE S Domain of unknown function (DUF3885)
HEEBIOIH_03613 4.2e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HEEBIOIH_03618 7.8e-08
HEEBIOIH_03626 2e-08
HEEBIOIH_03630 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HEEBIOIH_03631 1.1e-44 S LrgA family
HEEBIOIH_03632 6.1e-115 yxaC M effector of murein hydrolase
HEEBIOIH_03633 3e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HEEBIOIH_03634 3.5e-96 L Transposase
HEEBIOIH_03635 1.7e-159 ytbE S reductase
HEEBIOIH_03636 3.3e-201 ytbD EGP Major facilitator Superfamily
HEEBIOIH_03637 6.5e-15 ytcD K Transcriptional regulator
HEEBIOIH_03638 2.8e-41 ytcD K Transcriptional regulator
HEEBIOIH_03639 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEEBIOIH_03640 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HEEBIOIH_03641 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEEBIOIH_03642 7.7e-266 dnaB L Membrane attachment protein
HEEBIOIH_03643 3e-173 dnaI L Primosomal protein DnaI
HEEBIOIH_03644 1.6e-109 ytxB S SNARE associated Golgi protein
HEEBIOIH_03645 1.6e-157 ytxC S YtxC-like family
HEEBIOIH_03647 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEEBIOIH_03648 5.2e-147 ysaA S HAD-hyrolase-like
HEEBIOIH_03649 0.0 lytS 2.7.13.3 T Histidine kinase
HEEBIOIH_03650 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
HEEBIOIH_03651 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEEBIOIH_03652 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEEBIOIH_03654 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEEBIOIH_03655 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HEEBIOIH_03656 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEEBIOIH_03657 7.5e-45 ysdA S Membrane
HEEBIOIH_03658 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HEEBIOIH_03659 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HEEBIOIH_03660 4e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HEEBIOIH_03661 1e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HEEBIOIH_03662 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HEEBIOIH_03663 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HEEBIOIH_03664 2.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HEEBIOIH_03665 3.1e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HEEBIOIH_03666 5.8e-252 araN G carbohydrate transport
HEEBIOIH_03667 4.2e-167 araP G carbohydrate transport
HEEBIOIH_03668 9.9e-144 araQ G transport system permease
HEEBIOIH_03669 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HEEBIOIH_03670 0.0 cstA T Carbon starvation protein
HEEBIOIH_03672 6.2e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
HEEBIOIH_03673 8.3e-254 glcF C Glycolate oxidase
HEEBIOIH_03674 3.1e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
HEEBIOIH_03675 5.9e-205 ysfB KT regulator
HEEBIOIH_03676 2.6e-32 sspI S Belongs to the SspI family
HEEBIOIH_03677 1.1e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEEBIOIH_03678 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEEBIOIH_03679 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEEBIOIH_03680 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEEBIOIH_03681 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEEBIOIH_03682 1.7e-85 cvpA S membrane protein, required for colicin V production
HEEBIOIH_03683 0.0 polX L COG1796 DNA polymerase IV (family X)
HEEBIOIH_03684 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEEBIOIH_03685 7.3e-68 yshE S membrane
HEEBIOIH_03686 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEEBIOIH_03687 4e-99 fadR K Transcriptional regulator
HEEBIOIH_03688 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HEEBIOIH_03689 3.8e-134 etfB C Electron transfer flavoprotein
HEEBIOIH_03690 5.1e-176 etfA C Electron transfer flavoprotein
HEEBIOIH_03692 4.1e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HEEBIOIH_03693 2e-52 trxA O Belongs to the thioredoxin family
HEEBIOIH_03694 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEEBIOIH_03695 2.7e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HEEBIOIH_03696 1.2e-79 yslB S Protein of unknown function (DUF2507)
HEEBIOIH_03697 2.4e-107 sdhC C succinate dehydrogenase
HEEBIOIH_03698 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HEEBIOIH_03699 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HEEBIOIH_03700 2.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HEEBIOIH_03701 3.3e-30 gerE K Transcriptional regulator
HEEBIOIH_03702 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HEEBIOIH_03703 3.9e-153 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HEEBIOIH_03704 2.9e-196 gerM S COG5401 Spore germination protein
HEEBIOIH_03705 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HEEBIOIH_03706 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEEBIOIH_03707 4.1e-92 ysnB S Phosphoesterase
HEEBIOIH_03709 3.8e-132 ysnF S protein conserved in bacteria
HEEBIOIH_03710 1.8e-78 ysnE K acetyltransferase
HEEBIOIH_03712 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HEEBIOIH_03713 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HEEBIOIH_03714 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEEBIOIH_03715 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEEBIOIH_03716 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEEBIOIH_03717 1.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEEBIOIH_03718 2.6e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEEBIOIH_03719 5.1e-187 ysoA H Tetratricopeptide repeat
HEEBIOIH_03720 1.6e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEEBIOIH_03721 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEEBIOIH_03722 1.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HEEBIOIH_03723 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEEBIOIH_03724 5.7e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HEEBIOIH_03725 1.4e-89 ysxD
HEEBIOIH_03726 4.6e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HEEBIOIH_03727 3.6e-146 hemX O cytochrome C
HEEBIOIH_03728 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HEEBIOIH_03729 1.3e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HEEBIOIH_03730 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HEEBIOIH_03731 1.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HEEBIOIH_03732 1.1e-211 spoVID M stage VI sporulation protein D
HEEBIOIH_03733 5e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEEBIOIH_03734 1.6e-25
HEEBIOIH_03735 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEEBIOIH_03736 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HEEBIOIH_03737 2.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HEEBIOIH_03738 2.3e-163 spoIIB S Sporulation related domain
HEEBIOIH_03739 2.8e-102 maf D septum formation protein Maf
HEEBIOIH_03740 5.9e-126 radC E Belongs to the UPF0758 family
HEEBIOIH_03741 1.8e-184 mreB D Rod shape-determining protein MreB
HEEBIOIH_03742 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HEEBIOIH_03743 1.4e-84 mreD M shape-determining protein
HEEBIOIH_03744 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEEBIOIH_03745 4.7e-143 minD D Belongs to the ParA family
HEEBIOIH_03746 1.1e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HEEBIOIH_03747 2e-160 spoIVFB S Stage IV sporulation protein
HEEBIOIH_03748 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HEEBIOIH_03749 4.1e-56 ysxB J ribosomal protein
HEEBIOIH_03750 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HEEBIOIH_03751 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HEEBIOIH_03752 4.3e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEEBIOIH_03753 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HEEBIOIH_03754 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
HEEBIOIH_03755 2.3e-93 niaR S small molecule binding protein (contains 3H domain)
HEEBIOIH_03756 5.9e-227 nifS 2.8.1.7 E Cysteine desulfurase
HEEBIOIH_03757 3.2e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HEEBIOIH_03758 3.4e-155 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HEEBIOIH_03759 9.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HEEBIOIH_03760 2.6e-134 safA M spore coat assembly protein SafA
HEEBIOIH_03761 6e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEEBIOIH_03762 6.1e-126 yebC K transcriptional regulatory protein
HEEBIOIH_03763 4.5e-261 alsT E Sodium alanine symporter
HEEBIOIH_03764 4e-51 S Family of unknown function (DUF5412)
HEEBIOIH_03766 6.5e-119 yrzF T serine threonine protein kinase
HEEBIOIH_03767 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HEEBIOIH_03768 5.3e-253 csbX EGP Major facilitator Superfamily
HEEBIOIH_03769 4.8e-93 bofC S BofC C-terminal domain
HEEBIOIH_03770 4.5e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEEBIOIH_03771 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEEBIOIH_03772 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HEEBIOIH_03773 5.7e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEEBIOIH_03774 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEEBIOIH_03775 8e-39 yajC U Preprotein translocase subunit YajC
HEEBIOIH_03776 3.8e-73 yrzE S Protein of unknown function (DUF3792)
HEEBIOIH_03777 6.6e-111 yrbG S membrane
HEEBIOIH_03778 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEEBIOIH_03779 9.4e-49 yrzD S Post-transcriptional regulator
HEEBIOIH_03780 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEEBIOIH_03781 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HEEBIOIH_03782 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HEEBIOIH_03783 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HEEBIOIH_03784 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEEBIOIH_03785 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEEBIOIH_03786 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEEBIOIH_03787 1.1e-260 lytH 3.5.1.28 M COG3103 SH3 domain protein
HEEBIOIH_03789 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HEEBIOIH_03790 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HEEBIOIH_03791 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HEEBIOIH_03792 1.7e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HEEBIOIH_03793 1.2e-70 cymR K Transcriptional regulator
HEEBIOIH_03794 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
HEEBIOIH_03795 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEEBIOIH_03796 1.4e-15 S COG0457 FOG TPR repeat
HEEBIOIH_03797 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEEBIOIH_03798 6.6e-81 yrrD S protein conserved in bacteria
HEEBIOIH_03799 9.8e-31 yrzR
HEEBIOIH_03800 8e-08 S Protein of unknown function (DUF3918)
HEEBIOIH_03801 7.6e-107 glnP P ABC transporter
HEEBIOIH_03802 2.3e-108 gluC P ABC transporter
HEEBIOIH_03803 2.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
HEEBIOIH_03804 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEEBIOIH_03805 2.5e-168 yrrI S AI-2E family transporter
HEEBIOIH_03806 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEEBIOIH_03807 1.7e-41 yrzL S Belongs to the UPF0297 family
HEEBIOIH_03808 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEEBIOIH_03809 1.2e-45 yrzB S Belongs to the UPF0473 family
HEEBIOIH_03810 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEEBIOIH_03811 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
HEEBIOIH_03812 7.8e-174 yegQ O Peptidase U32
HEEBIOIH_03813 1.4e-245 yegQ O COG0826 Collagenase and related proteases
HEEBIOIH_03814 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HEEBIOIH_03815 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEEBIOIH_03816 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HEEBIOIH_03817 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HEEBIOIH_03818 3.5e-26 yrzA S Protein of unknown function (DUF2536)
HEEBIOIH_03819 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HEEBIOIH_03820 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEEBIOIH_03821 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HEEBIOIH_03822 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HEEBIOIH_03823 4.6e-35 yrhC S YrhC-like protein
HEEBIOIH_03824 7.1e-78 yrhD S Protein of unknown function (DUF1641)
HEEBIOIH_03825 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HEEBIOIH_03826 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
HEEBIOIH_03827 3e-142 focA P Formate nitrite
HEEBIOIH_03830 1e-93 yrhH Q methyltransferase
HEEBIOIH_03831 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HEEBIOIH_03832 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HEEBIOIH_03833 9e-44 yrhK S YrhK-like protein
HEEBIOIH_03834 0.0 yrhL I Acyltransferase family
HEEBIOIH_03835 7.2e-150 rsiV S Protein of unknown function (DUF3298)
HEEBIOIH_03836 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HEEBIOIH_03837 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
HEEBIOIH_03838 3.1e-105 yrhP E LysE type translocator
HEEBIOIH_03839 3.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HEEBIOIH_03840 0.0 levR K PTS system fructose IIA component
HEEBIOIH_03841 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
HEEBIOIH_03842 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HEEBIOIH_03843 4.4e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HEEBIOIH_03844 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HEEBIOIH_03845 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HEEBIOIH_03846 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HEEBIOIH_03847 2.4e-195 adhA 1.1.1.1 C alcohol dehydrogenase
HEEBIOIH_03848 4.4e-47 yraB K helix_turn_helix, mercury resistance
HEEBIOIH_03849 1.1e-22 yraD M Spore coat protein
HEEBIOIH_03850 2.3e-87 L Tn3 transposase DDE domain
HEEBIOIH_03851 1.5e-75
HEEBIOIH_03852 1.2e-238 L COG3328 Transposase and inactivated derivatives
HEEBIOIH_03853 9.1e-50 L Transposase
HEEBIOIH_03854 2e-137 L COG2801 Transposase and inactivated derivatives
HEEBIOIH_03859 2e-08
HEEBIOIH_03864 1.5e-134 L Integrase core domain
HEEBIOIH_03865 6e-44 tnpIS3 L Transposase
HEEBIOIH_03866 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEEBIOIH_03869 2e-08
HEEBIOIH_03873 1.2e-13 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HEEBIOIH_03874 1.5e-38 EG Spore germination protein
HEEBIOIH_03875 3e-36 L transposase activity
HEEBIOIH_03876 2.4e-87
HEEBIOIH_03877 1.6e-186 3.5.1.28 M Ami_2
HEEBIOIH_03878 4.4e-32 bhlA S BhlA holin family
HEEBIOIH_03879 5.5e-40 S SPP1 phage holin
HEEBIOIH_03880 3.4e-74 O protein disulfide oxidoreductase activity
HEEBIOIH_03881 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HEEBIOIH_03882 1.2e-70 CO cell redox homeostasis
HEEBIOIH_03883 0.0 V Peptidase C39 family
HEEBIOIH_03886 1.9e-236 S impB/mucB/samB family C-terminal domain
HEEBIOIH_03887 4.6e-52 S YolD-like protein
HEEBIOIH_03888 1.3e-40
HEEBIOIH_03890 4e-09 S Domain of unknown function (DUF4879)
HEEBIOIH_03892 1.3e-96 J Acetyltransferase (GNAT) domain
HEEBIOIH_03893 1.2e-94 yokK S SMI1 / KNR4 family
HEEBIOIH_03894 2.3e-78 S SMI1-KNR4 cell-wall
HEEBIOIH_03895 6.7e-86 S SMI1-KNR4 cell-wall
HEEBIOIH_03896 8.8e-307 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HEEBIOIH_03897 1.5e-65 G SMI1-KNR4 cell-wall
HEEBIOIH_03898 4.6e-36
HEEBIOIH_03899 1.5e-105 yokF 3.1.31.1 L RNA catabolic process
HEEBIOIH_03900 2.6e-54 S DNase/tRNase domain of colicin-like bacteriocin
HEEBIOIH_03901 7.1e-65 S SMI1 / KNR4 family
HEEBIOIH_03903 4.9e-240 yokA L Recombinase
HEEBIOIH_03904 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
HEEBIOIH_03905 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HEEBIOIH_03906 3.9e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEEBIOIH_03907 1.6e-70 ypoP K transcriptional
HEEBIOIH_03908 1.9e-221 mepA V MATE efflux family protein
HEEBIOIH_03909 1.2e-28 ypmT S Uncharacterized ympT
HEEBIOIH_03910 1.1e-98 ypmS S protein conserved in bacteria
HEEBIOIH_03911 1.1e-136 ypmR E GDSL-like Lipase/Acylhydrolase
HEEBIOIH_03912 1.3e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HEEBIOIH_03913 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HEEBIOIH_03914 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEEBIOIH_03915 6.8e-184 pspF K Transcriptional regulator
HEEBIOIH_03916 4.2e-110 hlyIII S protein, Hemolysin III
HEEBIOIH_03917 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEEBIOIH_03918 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEEBIOIH_03919 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEEBIOIH_03920 3.6e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HEEBIOIH_03921 5.5e-104 ypjP S YpjP-like protein
HEEBIOIH_03922 6.5e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HEEBIOIH_03923 1.7e-75 yphP S Belongs to the UPF0403 family
HEEBIOIH_03924 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HEEBIOIH_03925 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
HEEBIOIH_03926 6.7e-58 ypgQ S phosphohydrolase
HEEBIOIH_03927 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HEEBIOIH_03928 1.2e-174 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEEBIOIH_03929 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HEEBIOIH_03930 1e-30 cspD K Cold-shock protein
HEEBIOIH_03931 3.8e-16 degR
HEEBIOIH_03932 8.1e-31 S Protein of unknown function (DUF2564)
HEEBIOIH_03933 3e-29 ypeQ S Zinc-finger
HEEBIOIH_03934 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HEEBIOIH_03935 2.8e-120 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HEEBIOIH_03936 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
HEEBIOIH_03938 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HEEBIOIH_03939 2e-07
HEEBIOIH_03940 2.9e-38 ypbS S Protein of unknown function (DUF2533)
HEEBIOIH_03941 0.0 ypbR S Dynamin family
HEEBIOIH_03943 6.7e-87 ypbQ S protein conserved in bacteria
HEEBIOIH_03944 6.3e-207 bcsA Q Naringenin-chalcone synthase
HEEBIOIH_03945 2.9e-227 pbuX F xanthine
HEEBIOIH_03946 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEEBIOIH_03947 2.7e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HEEBIOIH_03948 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HEEBIOIH_03949 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HEEBIOIH_03950 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HEEBIOIH_03951 3.3e-186 ptxS K transcriptional
HEEBIOIH_03952 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HEEBIOIH_03953 1.3e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEEBIOIH_03954 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HEEBIOIH_03956 9.2e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HEEBIOIH_03957 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEEBIOIH_03958 5.3e-90 ypsA S Belongs to the UPF0398 family
HEEBIOIH_03959 1.9e-236 yprB L RNase_H superfamily
HEEBIOIH_03960 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HEEBIOIH_03961 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HEEBIOIH_03962 2.5e-71 hspX O Belongs to the small heat shock protein (HSP20) family
HEEBIOIH_03963 1.2e-48 yppG S YppG-like protein
HEEBIOIH_03965 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
HEEBIOIH_03968 2.6e-188 yppC S Protein of unknown function (DUF2515)
HEEBIOIH_03969 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEEBIOIH_03970 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HEEBIOIH_03971 4.7e-93 ypoC
HEEBIOIH_03972 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEEBIOIH_03973 5.7e-129 dnaD L DNA replication protein DnaD
HEEBIOIH_03974 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HEEBIOIH_03975 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HEEBIOIH_03976 3.4e-80 ypmB S protein conserved in bacteria
HEEBIOIH_03977 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HEEBIOIH_03978 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HEEBIOIH_03979 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HEEBIOIH_03980 6.8e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HEEBIOIH_03981 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HEEBIOIH_03982 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEEBIOIH_03983 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEEBIOIH_03984 2e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HEEBIOIH_03985 7.6e-129 bshB1 S proteins, LmbE homologs
HEEBIOIH_03986 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HEEBIOIH_03987 7e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEEBIOIH_03988 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HEEBIOIH_03989 1.8e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HEEBIOIH_03990 6.1e-143 ypjB S sporulation protein
HEEBIOIH_03991 1.1e-99 ypjA S membrane
HEEBIOIH_03992 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HEEBIOIH_03993 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HEEBIOIH_03994 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HEEBIOIH_03995 1e-75 ypiF S Protein of unknown function (DUF2487)
HEEBIOIH_03996 2.8e-99 ypiB S Belongs to the UPF0302 family
HEEBIOIH_03997 4.1e-234 S COG0457 FOG TPR repeat
HEEBIOIH_03998 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEEBIOIH_03999 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HEEBIOIH_04000 4.2e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEEBIOIH_04001 9.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEEBIOIH_04002 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEEBIOIH_04003 1e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HEEBIOIH_04004 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HEEBIOIH_04005 2.3e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEEBIOIH_04006 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEEBIOIH_04007 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HEEBIOIH_04008 6.5e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEEBIOIH_04009 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEEBIOIH_04010 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HEEBIOIH_04011 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HEEBIOIH_04012 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HEEBIOIH_04013 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEEBIOIH_04014 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HEEBIOIH_04015 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HEEBIOIH_04016 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HEEBIOIH_04017 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEEBIOIH_04018 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEEBIOIH_04019 6e-137 yphF
HEEBIOIH_04020 1.6e-18 yphE S Protein of unknown function (DUF2768)
HEEBIOIH_04021 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HEEBIOIH_04022 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HEEBIOIH_04023 6e-28 ypzH
HEEBIOIH_04024 7.2e-161 seaA S YIEGIA protein
HEEBIOIH_04025 1.9e-101 yphA
HEEBIOIH_04026 1e-07 S YpzI-like protein
HEEBIOIH_04027 4.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEEBIOIH_04028 3.1e-204 rpsA 1.17.7.4 J Ribosomal protein S1
HEEBIOIH_04029 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HEEBIOIH_04030 1.8e-23 S Family of unknown function (DUF5359)
HEEBIOIH_04031 5.2e-108 ypfA M Flagellar protein YcgR
HEEBIOIH_04032 9.3e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HEEBIOIH_04033 5.7e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HEEBIOIH_04034 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
HEEBIOIH_04035 2.1e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HEEBIOIH_04036 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HEEBIOIH_04037 9.1e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEEBIOIH_04038 3.4e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
HEEBIOIH_04039 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HEEBIOIH_04040 5.5e-74 ypbE M Lysin motif
HEEBIOIH_04041 6.9e-99 ypbD S metal-dependent membrane protease
HEEBIOIH_04042 6e-285 recQ 3.6.4.12 L DNA helicase
HEEBIOIH_04043 1.9e-200 ypbB 5.1.3.1 S protein conserved in bacteria
HEEBIOIH_04044 4.7e-41 fer C Ferredoxin
HEEBIOIH_04045 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEEBIOIH_04046 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEEBIOIH_04047 6.5e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEEBIOIH_04048 3.1e-198 rsiX
HEEBIOIH_04049 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HEEBIOIH_04050 0.0 resE 2.7.13.3 T Histidine kinase
HEEBIOIH_04051 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_04052 4.4e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HEEBIOIH_04053 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HEEBIOIH_04054 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HEEBIOIH_04055 2e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HEEBIOIH_04056 1.9e-87 spmB S Spore maturation protein
HEEBIOIH_04057 5.9e-103 spmA S Spore maturation protein
HEEBIOIH_04058 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HEEBIOIH_04059 4e-98 ypuI S Protein of unknown function (DUF3907)
HEEBIOIH_04060 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEEBIOIH_04061 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEEBIOIH_04062 3.9e-90 ypuF S Domain of unknown function (DUF309)
HEEBIOIH_04063 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEEBIOIH_04064 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEEBIOIH_04065 1.9e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEEBIOIH_04066 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
HEEBIOIH_04067 9.3e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEEBIOIH_04068 7.8e-55 ypuD
HEEBIOIH_04069 8e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HEEBIOIH_04071 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HEEBIOIH_04072 1.4e-08 S SNARE associated Golgi protein
HEEBIOIH_04074 4.7e-09 eaeH M Domain of Unknown Function (DUF1259)
HEEBIOIH_04076 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEEBIOIH_04077 1.3e-149 ypuA S Secreted protein
HEEBIOIH_04078 8.8e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEEBIOIH_04079 1.7e-271 spoVAF EG Stage V sporulation protein AF
HEEBIOIH_04080 1.4e-110 spoVAEA S stage V sporulation protein
HEEBIOIH_04081 2.2e-57 spoVAEB S stage V sporulation protein
HEEBIOIH_04082 2.9e-190 spoVAD I Stage V sporulation protein AD
HEEBIOIH_04083 2.3e-78 spoVAC S stage V sporulation protein AC
HEEBIOIH_04084 1e-67 spoVAB S Stage V sporulation protein AB
HEEBIOIH_04085 9.6e-112 spoVAA S Stage V sporulation protein AA
HEEBIOIH_04086 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEEBIOIH_04087 5.1e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HEEBIOIH_04088 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HEEBIOIH_04089 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HEEBIOIH_04090 3.8e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEEBIOIH_04091 6.7e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEEBIOIH_04092 2.6e-166 xerD L recombinase XerD
HEEBIOIH_04093 1.4e-36 S Protein of unknown function (DUF4227)
HEEBIOIH_04094 2.4e-80 fur P Belongs to the Fur family
HEEBIOIH_04095 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HEEBIOIH_04096 6.5e-31 yqkK
HEEBIOIH_04097 5.5e-242 mleA 1.1.1.38 C malic enzyme
HEEBIOIH_04098 9.1e-235 mleN C Na H antiporter
HEEBIOIH_04099 1.9e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HEEBIOIH_04100 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase
HEEBIOIH_04101 1.3e-57 ansR K Transcriptional regulator
HEEBIOIH_04102 3.1e-220 yqxK 3.6.4.12 L DNA helicase
HEEBIOIH_04103 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HEEBIOIH_04105 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HEEBIOIH_04106 9.1e-12 yqkE S Protein of unknown function (DUF3886)
HEEBIOIH_04107 1.2e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HEEBIOIH_04108 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HEEBIOIH_04109 2.8e-54 yqkB S Belongs to the HesB IscA family
HEEBIOIH_04110 2.2e-193 yqkA K GrpB protein
HEEBIOIH_04111 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HEEBIOIH_04112 8.1e-87 yqjY K acetyltransferase
HEEBIOIH_04113 1.7e-49 S YolD-like protein
HEEBIOIH_04114 2e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEEBIOIH_04116 5.8e-225 yqjV G Major Facilitator Superfamily
HEEBIOIH_04118 8.8e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEEBIOIH_04119 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HEEBIOIH_04120 2.1e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HEEBIOIH_04121 1.7e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEEBIOIH_04122 1.6e-177 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HEEBIOIH_04123 6.4e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEEBIOIH_04124 2.8e-26
HEEBIOIH_04125 1.2e-84 pacS 3.6.3.4, 3.6.3.54 P P-type atpase
HEEBIOIH_04126 2.3e-47 cysC 2.7.1.25 F Catalyzes the synthesis of activated sulfate
HEEBIOIH_04127 1.8e-98 amyE 3.2.1.1 GH13 G alpha-amylase
HEEBIOIH_04128 2.6e-269 amyE 3.2.1.1 GH13 G alpha-amylase
HEEBIOIH_04129 2.8e-46 ycgB
HEEBIOIH_04130 1.6e-255 ycgA S Membrane
HEEBIOIH_04131 5.6e-214 amhX S amidohydrolase
HEEBIOIH_04132 3.4e-163 opuAC E glycine betaine
HEEBIOIH_04133 1.3e-127 opuAB P glycine betaine
HEEBIOIH_04134 5.7e-228 proV 3.6.3.32 E glycine betaine
HEEBIOIH_04135 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HEEBIOIH_04136 3.2e-185 yceJ EGP Uncharacterised MFS-type transporter YbfB
HEEBIOIH_04137 3.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
HEEBIOIH_04138 2e-192 yceH P Belongs to the TelA family
HEEBIOIH_04139 0.0 yceG S Putative component of 'biosynthetic module'
HEEBIOIH_04140 6.3e-137 terC P Protein of unknown function (DUF475)
HEEBIOIH_04141 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HEEBIOIH_04142 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HEEBIOIH_04143 1.6e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HEEBIOIH_04144 2.8e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEEBIOIH_04145 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEEBIOIH_04146 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEEBIOIH_04147 1.6e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
HEEBIOIH_04148 9.8e-293 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HEEBIOIH_04149 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
HEEBIOIH_04150 6.7e-172 S response regulator aspartate phosphatase
HEEBIOIH_04151 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
HEEBIOIH_04152 2.6e-256 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HEEBIOIH_04153 9.4e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HEEBIOIH_04154 1.1e-179 ycdA S Domain of unknown function (DUF5105)
HEEBIOIH_04155 8.5e-90 yccK C Aldo keto reductase
HEEBIOIH_04156 6.5e-61 yccK C Aldo keto reductase
HEEBIOIH_04157 4.2e-201 natB CP ABC-2 family transporter protein
HEEBIOIH_04158 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HEEBIOIH_04159 2.5e-124 lytR_2 T LytTr DNA-binding domain
HEEBIOIH_04160 3.3e-159 2.7.13.3 T GHKL domain
HEEBIOIH_04161 2.3e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
HEEBIOIH_04162 4.6e-56 S RDD family
HEEBIOIH_04163 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEEBIOIH_04164 2.5e-150 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HEEBIOIH_04165 3.1e-101 yxaF K Transcriptional regulator
HEEBIOIH_04166 1.8e-230 lmrB EGP the major facilitator superfamily
HEEBIOIH_04167 1.6e-202 ycbU E Selenocysteine lyase
HEEBIOIH_04168 9.1e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEEBIOIH_04169 1.3e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEEBIOIH_04170 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEEBIOIH_04171 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HEEBIOIH_04172 1.1e-43 ycbR T vWA found in TerF C terminus
HEEBIOIH_04173 2.8e-64 ycbR T vWA found in TerF C terminus
HEEBIOIH_04174 2.5e-195 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEEBIOIH_04175 1.8e-70 argO S Lysine exporter protein LysE YggA
HEEBIOIH_04176 8.7e-122 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HEEBIOIH_04177 2.8e-30 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEEBIOIH_04178 1e-14 E argininosuccinate synthase activity
HEEBIOIH_04179 1.3e-82 S Protein of unknown function (DUF444)
HEEBIOIH_04180 2e-82 I Fatty acid desaturase
HEEBIOIH_04181 2.3e-123 yjeH E Amino acid permease
HEEBIOIH_04182 9.5e-99 asd 1.2.1.11, 1.2.1.12 E Belongs to the aspartate-semialdehyde dehydrogenase family
HEEBIOIH_04183 1.2e-34 S CGNR zinc finger
HEEBIOIH_04184 4.5e-40 MA20_18655 S flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase
HEEBIOIH_04185 1.5e-26 4.4.1.5 E lactoylglutathione lyase activity
HEEBIOIH_04186 9.7e-17 S NIPSNAP family containing protein
HEEBIOIH_04187 8.5e-51 S B3/4 domain
HEEBIOIH_04189 3.4e-76 sleB 3.5.1.28 M Cell wall
HEEBIOIH_04190 1.3e-50 ycbP S Protein of unknown function (DUF2512)
HEEBIOIH_04191 5.6e-113 S ABC-2 family transporter protein
HEEBIOIH_04192 3.1e-167 ycbN V ABC transporter, ATP-binding protein
HEEBIOIH_04193 1.5e-77 T PhoQ Sensor
HEEBIOIH_04194 2.7e-77 T PhoQ Sensor
HEEBIOIH_04195 6.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_04196 4.9e-168 eamA1 EG spore germination
HEEBIOIH_04197 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HEEBIOIH_04198 2.4e-53 ycbJ S Macrolide 2'-phosphotransferase
HEEBIOIH_04199 5.1e-96 ycbJ S Macrolide 2'-phosphotransferase
HEEBIOIH_04200 2.9e-78 garD 4.2.1.42, 4.2.1.7 G Altronate
HEEBIOIH_04201 1e-68 garD 4.2.1.42, 4.2.1.7 G Altronate
HEEBIOIH_04202 2.1e-123 ycbG K FCD
HEEBIOIH_04203 1.4e-267 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HEEBIOIH_04204 4.7e-157 gudP G COG0477 Permeases of the major facilitator superfamily
HEEBIOIH_04205 6.1e-48 gudP G COG0477 Permeases of the major facilitator superfamily
HEEBIOIH_04206 9e-273 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEEBIOIH_04207 1.9e-172 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HEEBIOIH_04208 6.5e-168 glnL T Regulator
HEEBIOIH_04209 4.7e-228 phoQ 2.7.13.3 T Histidine kinase
HEEBIOIH_04210 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
HEEBIOIH_04211 8.1e-255 agcS E Sodium alanine symporter
HEEBIOIH_04213 1.1e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HEEBIOIH_04214 3.3e-261 mmuP E amino acid
HEEBIOIH_04215 1.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HEEBIOIH_04217 3.1e-128 K UTRA
HEEBIOIH_04218 5.7e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEEBIOIH_04219 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEEBIOIH_04220 1.4e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEEBIOIH_04221 1.5e-191 yceA S Belongs to the UPF0176 family
HEEBIOIH_04222 9e-248 S Erythromycin esterase
HEEBIOIH_04223 2e-45 ybfN
HEEBIOIH_04224 1.6e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HEEBIOIH_04225 2.7e-85 ybfM S SNARE associated Golgi protein
HEEBIOIH_04226 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEEBIOIH_04227 1.6e-163 S Alpha/beta hydrolase family
HEEBIOIH_04229 1.1e-175 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HEEBIOIH_04230 2.2e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEEBIOIH_04231 3.3e-144 msmR K AraC-like ligand binding domain
HEEBIOIH_04232 1.3e-48 ybfH EG EamA-like transporter family
HEEBIOIH_04233 5.8e-67 ybfH EG EamA-like transporter family
HEEBIOIH_04234 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HEEBIOIH_04236 1e-221 ybfB G COG0477 Permeases of the major facilitator superfamily
HEEBIOIH_04237 2.2e-168 ybfA 3.4.15.5 K FR47-like protein
HEEBIOIH_04238 1.6e-33 S Protein of unknown function (DUF2651)
HEEBIOIH_04239 7.3e-258 glpT G -transporter
HEEBIOIH_04240 2.4e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HEEBIOIH_04241 1.5e-289 ybeC E amino acid
HEEBIOIH_04242 4.9e-41 ybyB
HEEBIOIH_04243 1.1e-32 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HEEBIOIH_04244 2.2e-169 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HEEBIOIH_04245 3.4e-149 ybxI 3.5.2.6 V beta-lactamase
HEEBIOIH_04246 4.9e-30 ybxH S Family of unknown function (DUF5370)
HEEBIOIH_04247 1.4e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
HEEBIOIH_04248 1.3e-257 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HEEBIOIH_04249 9.2e-212 ybdO S Domain of unknown function (DUF4885)
HEEBIOIH_04250 7.7e-152 ybdN
HEEBIOIH_04251 3.9e-139 KLT Protein tyrosine kinase
HEEBIOIH_04253 1.8e-168 T His Kinase A (phospho-acceptor) domain
HEEBIOIH_04254 1.3e-122 T Transcriptional regulatory protein, C terminal
HEEBIOIH_04255 5.5e-178 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEEBIOIH_04256 9.6e-79 txn CO Thioredoxin-like
HEEBIOIH_04257 7.8e-91 C HEAT repeats
HEEBIOIH_04258 8e-247 skfF S ABC transporter
HEEBIOIH_04259 7.5e-132 skfE V ABC transporter
HEEBIOIH_04260 2.5e-275 V CAAX protease self-immunity
HEEBIOIH_04261 9.1e-239 J 4Fe-4S single cluster domain
HEEBIOIH_04263 4.5e-203 ybcL EGP Major facilitator Superfamily
HEEBIOIH_04264 5.1e-50 ybzH K Helix-turn-helix domain
HEEBIOIH_04265 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HEEBIOIH_04266 8.7e-47
HEEBIOIH_04268 1.3e-93 can 4.2.1.1 P carbonic anhydrase
HEEBIOIH_04269 0.0 ybcC S Belongs to the UPF0753 family
HEEBIOIH_04270 7e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEEBIOIH_04271 1.4e-98 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEEBIOIH_04272 3.2e-118 adaA 3.2.2.21 K Transcriptional regulator
HEEBIOIH_04273 9.6e-169 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEEBIOIH_04274 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEEBIOIH_04275 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEEBIOIH_04276 5.7e-224 ybbR S protein conserved in bacteria
HEEBIOIH_04277 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEEBIOIH_04278 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HEEBIOIH_04279 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HEEBIOIH_04285 5.7e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HEEBIOIH_04286 1.9e-86 ybbJ J acetyltransferase
HEEBIOIH_04287 3.9e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEEBIOIH_04288 1.2e-149 ybbH K transcriptional
HEEBIOIH_04289 8.3e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HEEBIOIH_04290 1.4e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HEEBIOIH_04291 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HEEBIOIH_04292 1.6e-235 ybbC 3.2.1.52 S protein conserved in bacteria
HEEBIOIH_04293 1.4e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HEEBIOIH_04294 2.4e-162 feuA P Iron-uptake system-binding protein
HEEBIOIH_04295 4e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_04296 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_04297 8.6e-139 ybbA S Putative esterase
HEEBIOIH_04298 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
HEEBIOIH_04299 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HEEBIOIH_04301 2.6e-56 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEEBIOIH_04302 4.7e-28 ydiK_1 S permease
HEEBIOIH_04303 1.3e-23 S MbeB-like, N-term conserved region
HEEBIOIH_04304 1.2e-65 nifH 1.18.6.1 P The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein
HEEBIOIH_04305 1.3e-72 L Integrase core domain
HEEBIOIH_04306 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
HEEBIOIH_04307 7.5e-253 iolT EGP Major facilitator Superfamily
HEEBIOIH_04308 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEEBIOIH_04309 5.3e-83 yncE S Protein of unknown function (DUF2691)
HEEBIOIH_04310 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HEEBIOIH_04311 5.2e-15
HEEBIOIH_04314 1.9e-163 S Thymidylate synthase
HEEBIOIH_04315 5.4e-32
HEEBIOIH_04317 1.2e-126 S Domain of unknown function, YrpD
HEEBIOIH_04320 7.9e-25 tatA U protein secretion
HEEBIOIH_04321 1.3e-51
HEEBIOIH_04322 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HEEBIOIH_04325 9e-284 gerAA EG Spore germination protein
HEEBIOIH_04326 1e-193 gerAB U Spore germination
HEEBIOIH_04327 1.9e-182 gerLC S Spore germination protein
HEEBIOIH_04328 2.9e-153 yndG S DoxX-like family
HEEBIOIH_04329 5.5e-113 yndH S Domain of unknown function (DUF4166)
HEEBIOIH_04330 2.3e-306 yndJ S YndJ-like protein
HEEBIOIH_04332 1.5e-135 yndL S Replication protein
HEEBIOIH_04333 5.6e-92 yndM S Protein of unknown function (DUF2512)
HEEBIOIH_04334 1.1e-77 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HEEBIOIH_04335 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEEBIOIH_04336 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HEEBIOIH_04337 2.9e-111 yneB L resolvase
HEEBIOIH_04338 1.3e-32 ynzC S UPF0291 protein
HEEBIOIH_04339 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEEBIOIH_04340 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HEEBIOIH_04341 1.8e-28 yneF S UPF0154 protein
HEEBIOIH_04342 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HEEBIOIH_04343 7.1e-127 ccdA O cytochrome c biogenesis protein
HEEBIOIH_04344 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HEEBIOIH_04345 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HEEBIOIH_04346 1.2e-73 yneK S Protein of unknown function (DUF2621)
HEEBIOIH_04347 5.9e-64 hspX O Spore coat protein
HEEBIOIH_04348 3.9e-19 sspP S Belongs to the SspP family
HEEBIOIH_04349 2.2e-14 sspO S Belongs to the SspO family
HEEBIOIH_04350 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEEBIOIH_04351 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEEBIOIH_04353 3.1e-08 sspN S Small acid-soluble spore protein N family
HEEBIOIH_04354 3.9e-35 tlp S Belongs to the Tlp family
HEEBIOIH_04355 1.2e-73 yneP S Thioesterase-like superfamily
HEEBIOIH_04356 1.9e-52 yneQ
HEEBIOIH_04357 4.1e-49 yneR S Belongs to the HesB IscA family
HEEBIOIH_04358 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEEBIOIH_04359 6.6e-69 yccU S CoA-binding protein
HEEBIOIH_04360 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEEBIOIH_04361 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEEBIOIH_04362 2.3e-12
HEEBIOIH_04363 8.6e-57 ynfC
HEEBIOIH_04364 9e-251 agcS E Sodium alanine symporter
HEEBIOIH_04365 4.2e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HEEBIOIH_04367 2e-91 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HEEBIOIH_04368 1.8e-136 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HEEBIOIH_04369 1.4e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HEEBIOIH_04370 1.4e-75 yngA S membrane
HEEBIOIH_04371 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HEEBIOIH_04372 5.5e-104 yngC S membrane-associated protein
HEEBIOIH_04373 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
HEEBIOIH_04374 4.5e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEEBIOIH_04375 1.7e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HEEBIOIH_04376 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HEEBIOIH_04377 7.3e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HEEBIOIH_04378 5.6e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HEEBIOIH_04379 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEEBIOIH_04380 7e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HEEBIOIH_04381 8.5e-303 yngK T Glycosyl hydrolase-like 10
HEEBIOIH_04382 2.8e-64 yngL S Protein of unknown function (DUF1360)
HEEBIOIH_04383 2.6e-36 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HEEBIOIH_04384 2e-161 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HEEBIOIH_04385 1e-154 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HEEBIOIH_04386 1e-260 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HEEBIOIH_04387 1.7e-290 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEEBIOIH_04388 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEEBIOIH_04389 1.7e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HEEBIOIH_04390 6.9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
HEEBIOIH_04391 2.3e-246 yoeA V MATE efflux family protein
HEEBIOIH_04392 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HEEBIOIH_04394 2.2e-96 L Integrase
HEEBIOIH_04395 3e-34 yoeD G Helix-turn-helix domain
HEEBIOIH_04396 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HEEBIOIH_04397 8.8e-156 gltR1 K Transcriptional regulator
HEEBIOIH_04398 1.8e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEEBIOIH_04399 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HEEBIOIH_04400 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HEEBIOIH_04401 7.8e-155 gltC K Transcriptional regulator
HEEBIOIH_04402 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEEBIOIH_04403 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEEBIOIH_04404 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HEEBIOIH_04405 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HEEBIOIH_04406 6e-38 yoxC S Bacterial protein of unknown function (DUF948)
HEEBIOIH_04407 1.5e-69 yoxB
HEEBIOIH_04408 6e-94 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEEBIOIH_04409 4.5e-127 V ABC-2 family transporter protein
HEEBIOIH_04410 3.7e-94 V ABC-2 family transporter protein
HEEBIOIH_04411 9.7e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
HEEBIOIH_04412 2.5e-79 hpr K helix_turn_helix multiple antibiotic resistance protein
HEEBIOIH_04413 1.2e-233 yoaB EGP Major facilitator Superfamily
HEEBIOIH_04414 5.7e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HEEBIOIH_04415 1.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEEBIOIH_04416 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEEBIOIH_04417 6.5e-34 yoaF
HEEBIOIH_04418 5e-08 ywlA S Uncharacterised protein family (UPF0715)
HEEBIOIH_04419 2.6e-13
HEEBIOIH_04420 1.3e-37 S Protein of unknown function (DUF4025)
HEEBIOIH_04421 1.6e-130 mcpU NT methyl-accepting chemotaxis protein
HEEBIOIH_04422 6.2e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HEEBIOIH_04423 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HEEBIOIH_04424 5.2e-111 yoaK S Membrane
HEEBIOIH_04425 5.2e-195 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HEEBIOIH_04426 6.6e-130 yoqW S Belongs to the SOS response-associated peptidase family
HEEBIOIH_04428 5e-164 oxdC 4.1.1.2 G Oxalate decarboxylase
HEEBIOIH_04429 1.2e-52 oxdC 4.1.1.2 G Oxalate decarboxylase
HEEBIOIH_04432 4.9e-36
HEEBIOIH_04433 1.1e-169 yoaR V vancomycin resistance protein
HEEBIOIH_04434 7.3e-75 yoaS S Protein of unknown function (DUF2975)
HEEBIOIH_04435 4.4e-30 yozG K Transcriptional regulator
HEEBIOIH_04436 2.4e-147 yoaT S Protein of unknown function (DUF817)
HEEBIOIH_04437 8.2e-158 yoaU K LysR substrate binding domain
HEEBIOIH_04438 5.3e-156 yijE EG EamA-like transporter family
HEEBIOIH_04439 1.6e-76 yoaW
HEEBIOIH_04440 4.5e-16 ybbC 3.2.1.52 S protein conserved in bacteria
HEEBIOIH_04441 4.5e-16 ybbC 3.2.1.52 S protein conserved in bacteria
HEEBIOIH_04442 6.7e-59 ydbC 1.1.1.65 C oxidoreductase
HEEBIOIH_04443 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HEEBIOIH_04444 4.4e-289 lctP C L-lactate permease
HEEBIOIH_04445 3.9e-263 mdr EGP Major facilitator Superfamily
HEEBIOIH_04446 2.2e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
HEEBIOIH_04447 4.5e-109 ycgF E Lysine exporter protein LysE YggA
HEEBIOIH_04448 1.4e-149 yqcI S YqcI/YcgG family
HEEBIOIH_04449 2.4e-153 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HEEBIOIH_04450 4.3e-94 ycgI S Domain of unknown function (DUF1989)
HEEBIOIH_04451 1.7e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEEBIOIH_04452 2.6e-86 tmrB S AAA domain
HEEBIOIH_04453 6.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEEBIOIH_04454 2.2e-142 yafE Q ubiE/COQ5 methyltransferase family
HEEBIOIH_04455 2.2e-179 oxyR3 K LysR substrate binding domain
HEEBIOIH_04456 5.5e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HEEBIOIH_04457 2.9e-145 ycgL S Predicted nucleotidyltransferase
HEEBIOIH_04458 5.1e-170 ycgM E Proline dehydrogenase
HEEBIOIH_04459 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEEBIOIH_04460 7.5e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEEBIOIH_04461 3.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HEEBIOIH_04462 2.6e-147 ycgQ S membrane
HEEBIOIH_04463 6.5e-138 ycgR S permeases
HEEBIOIH_04464 8.5e-159 I alpha/beta hydrolase fold
HEEBIOIH_04465 1.9e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HEEBIOIH_04466 5.4e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HEEBIOIH_04467 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HEEBIOIH_04468 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HEEBIOIH_04469 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEEBIOIH_04470 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HEEBIOIH_04471 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
HEEBIOIH_04472 1.2e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HEEBIOIH_04473 4.2e-101 yciB M ErfK YbiS YcfS YnhG
HEEBIOIH_04474 3.6e-112 yciC S GTPases (G3E family)
HEEBIOIH_04475 1.8e-98 yciC S GTPases (G3E family)
HEEBIOIH_04476 1e-114 yecS P COG0765 ABC-type amino acid transport system, permease component
HEEBIOIH_04477 1.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HEEBIOIH_04479 3.7e-42 yckC S membrane
HEEBIOIH_04480 7.8e-52 yckD S Protein of unknown function (DUF2680)
HEEBIOIH_04481 2e-21 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEEBIOIH_04482 4.8e-248 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HEEBIOIH_04483 8.5e-69 nin S Competence protein J (ComJ)
HEEBIOIH_04484 5.6e-69 nucA M Deoxyribonuclease NucA/NucB
HEEBIOIH_04485 2.7e-56 tlpC 2.7.13.3 NT chemotaxis protein
HEEBIOIH_04486 7.8e-115 tlpC 2.7.13.3 NT chemotaxis protein
HEEBIOIH_04487 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HEEBIOIH_04488 4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HEEBIOIH_04489 6.3e-63 hxlR K transcriptional
HEEBIOIH_04490 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEEBIOIH_04491 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEEBIOIH_04492 7.2e-115 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEEBIOIH_04493 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HEEBIOIH_04494 4.9e-139 srfAD Q thioesterase
HEEBIOIH_04495 4.4e-225 EGP Major Facilitator Superfamily
HEEBIOIH_04496 4.8e-86 S YcxB-like protein
HEEBIOIH_04497 5.8e-161 ycxC EG EamA-like transporter family
HEEBIOIH_04498 8.9e-237 ycxD K GntR family transcriptional regulator
HEEBIOIH_04499 9.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HEEBIOIH_04500 9.7e-115 yczE S membrane
HEEBIOIH_04501 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HEEBIOIH_04502 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HEEBIOIH_04503 8.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HEEBIOIH_04504 1.1e-158 bsdA K LysR substrate binding domain
HEEBIOIH_04505 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEEBIOIH_04506 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HEEBIOIH_04507 4e-39 bsdD 4.1.1.61 S response to toxic substance
HEEBIOIH_04508 2.7e-82 yclD
HEEBIOIH_04509 6e-157 yclE 3.4.11.5 S Alpha beta hydrolase
HEEBIOIH_04510 7.3e-267 dtpT E amino acid peptide transporter
HEEBIOIH_04511 1.9e-298 yclG M Pectate lyase superfamily protein
HEEBIOIH_04513 1.9e-276 gerKA EG Spore germination protein
HEEBIOIH_04514 8e-227 gerKC S spore germination
HEEBIOIH_04515 1e-196 gerKB F Spore germination protein
HEEBIOIH_04516 1.5e-121 yclH P ABC transporter
HEEBIOIH_04517 4e-201 yclI V ABC transporter (permease) YclI
HEEBIOIH_04518 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEEBIOIH_04519 1.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HEEBIOIH_04520 1.4e-71 S aspartate phosphatase
HEEBIOIH_04523 2.8e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
HEEBIOIH_04524 3e-35 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_04525 5.8e-98 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_04526 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEEBIOIH_04527 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HEEBIOIH_04528 1.5e-172 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HEEBIOIH_04529 1.4e-251 ycnB EGP Major facilitator Superfamily
HEEBIOIH_04530 7.9e-152 ycnC K Transcriptional regulator
HEEBIOIH_04531 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HEEBIOIH_04532 1.6e-45 ycnE S Monooxygenase
HEEBIOIH_04533 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HEEBIOIH_04534 3.6e-271 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEEBIOIH_04535 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEEBIOIH_04536 1.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEEBIOIH_04537 6.1e-149 glcU U Glucose uptake
HEEBIOIH_04538 1.4e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEEBIOIH_04539 6.6e-97 ycnI S protein conserved in bacteria
HEEBIOIH_04540 1.1e-305 ycnJ P protein, homolog of Cu resistance protein CopC
HEEBIOIH_04541 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HEEBIOIH_04542 2.6e-53
HEEBIOIH_04543 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HEEBIOIH_04544 2.4e-69 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HEEBIOIH_04545 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HEEBIOIH_04546 1.1e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HEEBIOIH_04547 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HEEBIOIH_04548 6e-73 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HEEBIOIH_04549 8.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HEEBIOIH_04550 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)