ORF_ID e_value Gene_name EC_number CAZy COGs Description
IKDGHLII_00001 1.6e-49
IKDGHLII_00002 5.5e-50 2.7.7.7 L EXOIII
IKDGHLII_00003 4.7e-95 L 3'-5' exonuclease
IKDGHLII_00005 8.1e-41
IKDGHLII_00006 1.1e-32
IKDGHLII_00007 3.7e-39
IKDGHLII_00011 4.2e-50
IKDGHLII_00012 1.7e-07 S Cro/C1-type HTH DNA-binding domain
IKDGHLII_00013 3.9e-08 K Cro/C1-type HTH DNA-binding domain
IKDGHLII_00014 1e-131 dnaG L Toprim-like
IKDGHLII_00015 2.5e-144 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
IKDGHLII_00017 2.9e-08 yodN
IKDGHLII_00019 3.3e-88 L DNA-dependent DNA replication
IKDGHLII_00021 2.5e-61
IKDGHLII_00023 2e-16
IKDGHLII_00026 2.9e-35
IKDGHLII_00029 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IKDGHLII_00030 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IKDGHLII_00031 1.7e-78 queD 4.1.2.50, 4.2.3.12 H synthase
IKDGHLII_00032 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IKDGHLII_00033 2.5e-182
IKDGHLII_00034 1.7e-182 ykvI S membrane
IKDGHLII_00035 0.0 clpE O Belongs to the ClpA ClpB family
IKDGHLII_00036 3.3e-136 motA N flagellar motor
IKDGHLII_00037 2.7e-127 motB N Flagellar motor protein
IKDGHLII_00038 5.5e-77 ykvE K transcriptional
IKDGHLII_00039 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
IKDGHLII_00040 3.4e-10 S Spo0E like sporulation regulatory protein
IKDGHLII_00041 7.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IKDGHLII_00042 5.2e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IKDGHLII_00043 2.7e-128 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IKDGHLII_00044 4.3e-225 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IKDGHLII_00045 1.7e-226 mtnE 2.6.1.83 E Aminotransferase
IKDGHLII_00046 2.9e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IKDGHLII_00047 1.5e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IKDGHLII_00048 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IKDGHLII_00050 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IKDGHLII_00051 0.0 kinE 2.7.13.3 T Histidine kinase
IKDGHLII_00052 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
IKDGHLII_00053 8.7e-23 ykzE
IKDGHLII_00054 7.2e-113 ydfR S Protein of unknown function (DUF421)
IKDGHLII_00055 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
IKDGHLII_00056 4.5e-155 htpX O Belongs to the peptidase M48B family
IKDGHLII_00057 2.9e-125 ykrK S Domain of unknown function (DUF1836)
IKDGHLII_00058 2.5e-26 sspD S small acid-soluble spore protein
IKDGHLII_00059 1.5e-118 rsgI S Anti-sigma factor N-terminus
IKDGHLII_00060 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKDGHLII_00061 1.1e-133 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IKDGHLII_00062 3.8e-99 ykoX S membrane-associated protein
IKDGHLII_00063 4.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IKDGHLII_00064 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
IKDGHLII_00065 3.7e-99 ykoP G polysaccharide deacetylase
IKDGHLII_00066 1.1e-80 ykoM K transcriptional
IKDGHLII_00067 3.1e-26 ykoL
IKDGHLII_00068 1.9e-16
IKDGHLII_00069 5.4e-53 tnrA K transcriptional
IKDGHLII_00070 3e-235 mgtE P Acts as a magnesium transporter
IKDGHLII_00072 3.3e-244 ydhD M Glycosyl hydrolase
IKDGHLII_00073 1e-97 ykoE S ABC-type cobalt transport system, permease component
IKDGHLII_00074 1.3e-301 P ABC transporter, ATP-binding protein
IKDGHLII_00075 2.1e-132 ykoC P Cobalt transport protein
IKDGHLII_00076 4.3e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IKDGHLII_00077 5e-176 isp O Belongs to the peptidase S8 family
IKDGHLII_00078 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IKDGHLII_00079 9.8e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IKDGHLII_00080 1.2e-214 hcaT 1.5.1.2 EGP Major facilitator Superfamily
IKDGHLII_00081 9.3e-123 M PFAM Collagen triple helix repeat (20 copies)
IKDGHLII_00082 1.1e-214 M Glycosyl transferase family 2
IKDGHLII_00084 3.5e-55 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IKDGHLII_00085 4.2e-71 ohrB O Organic hydroperoxide resistance protein
IKDGHLII_00086 4.1e-72 ohrR K COG1846 Transcriptional regulators
IKDGHLII_00087 1.8e-41 ohrA O Organic hydroperoxide resistance protein
IKDGHLII_00088 2.4e-223 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IKDGHLII_00089 2.7e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IKDGHLII_00090 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IKDGHLII_00091 1e-48 ykkD P Multidrug resistance protein
IKDGHLII_00092 1.4e-51 ykkC P Multidrug resistance protein
IKDGHLII_00093 7.4e-100 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IKDGHLII_00094 9.2e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
IKDGHLII_00095 2.7e-157 ykgA E Amidinotransferase
IKDGHLII_00096 5.6e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
IKDGHLII_00097 1.1e-181 ykfD E Belongs to the ABC transporter superfamily
IKDGHLII_00098 1.6e-168 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IKDGHLII_00099 2e-197 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IKDGHLII_00100 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IKDGHLII_00101 0.0 dppE E ABC transporter substrate-binding protein
IKDGHLII_00102 5.9e-191 dppD P Belongs to the ABC transporter superfamily
IKDGHLII_00103 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKDGHLII_00104 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKDGHLII_00105 1.9e-155 dppA E D-aminopeptidase
IKDGHLII_00106 4.8e-277 yubD P Major Facilitator Superfamily
IKDGHLII_00107 4.7e-204 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IKDGHLII_00108 1.5e-16 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IKDGHLII_00109 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IKDGHLII_00110 1.1e-303 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IKDGHLII_00111 1.2e-177 mhqA E COG0346 Lactoylglutathione lyase and related lyases
IKDGHLII_00112 3.2e-242 steT E amino acid
IKDGHLII_00113 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
IKDGHLII_00114 5.8e-175 pit P phosphate transporter
IKDGHLII_00115 2.2e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
IKDGHLII_00116 8.7e-23 spoIISB S Stage II sporulation protein SB
IKDGHLII_00117 5.4e-169 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IKDGHLII_00118 1.3e-38 xhlB S SPP1 phage holin
IKDGHLII_00119 8.7e-38 xhlA S Haemolysin XhlA
IKDGHLII_00120 2.6e-135 xepA
IKDGHLII_00121 1.6e-28 xkdX
IKDGHLII_00123 1.7e-91
IKDGHLII_00124 1.2e-26
IKDGHLII_00125 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
IKDGHLII_00126 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IKDGHLII_00127 4.2e-58 xkdS S Protein of unknown function (DUF2634)
IKDGHLII_00128 7.2e-32 xkdR S Protein of unknown function (DUF2577)
IKDGHLII_00129 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
IKDGHLII_00130 1.5e-110 xkdP S Lysin motif
IKDGHLII_00131 1.3e-193 xkdO L Transglycosylase SLT domain
IKDGHLII_00132 3.4e-19
IKDGHLII_00133 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
IKDGHLII_00134 2e-74 xkdM S Phage tail tube protein
IKDGHLII_00135 2.6e-226 xkdK S Phage tail sheath C-terminal domain
IKDGHLII_00136 8.2e-15
IKDGHLII_00137 1.4e-56 xkdJ
IKDGHLII_00138 9e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
IKDGHLII_00139 5.5e-43 yqbH S Domain of unknown function (DUF3599)
IKDGHLII_00140 3.3e-46 yqbG S Protein of unknown function (DUF3199)
IKDGHLII_00141 1e-157 xkdG S Phage capsid family
IKDGHLII_00142 1.7e-90 xkdF 2.1.1.72 L Putative phage serine protease XkdF
IKDGHLII_00143 3e-241 yqbA S portal protein
IKDGHLII_00144 5e-211 xtmB S phage terminase, large subunit
IKDGHLII_00145 6.8e-110 xtmA L phage terminase small subunit
IKDGHLII_00146 5.4e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IKDGHLII_00147 2e-10 yqaO S Phage-like element PBSX protein XtrA
IKDGHLII_00150 2.3e-150 xkdC L Bacterial dnaA protein
IKDGHLII_00152 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
IKDGHLII_00153 2.9e-110 xkdA E IrrE N-terminal-like domain
IKDGHLII_00154 1.4e-110 yjqB S phage-related replication protein
IKDGHLII_00155 8e-61 yjqA S Bacterial PH domain
IKDGHLII_00156 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IKDGHLII_00158 4.2e-214 S response regulator aspartate phosphatase
IKDGHLII_00159 8.9e-78 yjoA S DinB family
IKDGHLII_00160 2.5e-130 MA20_18170 S membrane transporter protein
IKDGHLII_00162 2.1e-15 V ABC transporter, ATP-binding protein
IKDGHLII_00163 1.4e-131 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IKDGHLII_00164 4e-87 T Transcriptional regulatory protein, C terminal
IKDGHLII_00165 2.3e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
IKDGHLII_00166 2e-277 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
IKDGHLII_00167 7e-181 exuR K transcriptional
IKDGHLII_00168 2.5e-253 yjmB G symporter YjmB
IKDGHLII_00169 6.9e-275 uxaC 5.3.1.12 G glucuronate isomerase
IKDGHLII_00170 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
IKDGHLII_00171 7e-66 yjlC S Protein of unknown function (DUF1641)
IKDGHLII_00172 5.7e-91 yjlB S Cupin domain
IKDGHLII_00173 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
IKDGHLII_00174 7.1e-130 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
IKDGHLII_00175 2.1e-124 ybbM S transport system, permease component
IKDGHLII_00176 5.1e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IKDGHLII_00177 6.8e-29
IKDGHLII_00178 2e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IKDGHLII_00179 3.3e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
IKDGHLII_00180 4.3e-92 yjgD S Protein of unknown function (DUF1641)
IKDGHLII_00181 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
IKDGHLII_00182 8.6e-99 yjgB S Domain of unknown function (DUF4309)
IKDGHLII_00183 2.6e-65 T PhoQ Sensor
IKDGHLII_00184 7.5e-22 yjfB S Putative motility protein
IKDGHLII_00186 8.1e-106 yhiD S MgtC SapB transporter
IKDGHLII_00188 1.3e-122 5.4.2.6 S Haloacid dehalogenase-like hydrolase
IKDGHLII_00189 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
IKDGHLII_00190 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IKDGHLII_00191 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
IKDGHLII_00192 1.7e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IKDGHLII_00193 2.2e-213 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IKDGHLII_00194 1.2e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IKDGHLII_00195 2.4e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IKDGHLII_00196 3.8e-220 ganA 3.2.1.89 G arabinogalactan
IKDGHLII_00197 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
IKDGHLII_00198 6.5e-249 yfjF EGP Belongs to the major facilitator superfamily
IKDGHLII_00199 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
IKDGHLII_00200 9.7e-161 bla 3.5.2.6 V beta-lactamase
IKDGHLII_00201 8.5e-58 E Glyoxalase-like domain
IKDGHLII_00203 6.2e-204 M nucleic acid phosphodiester bond hydrolysis
IKDGHLII_00204 2.9e-29
IKDGHLII_00205 7.7e-22
IKDGHLII_00207 7.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IKDGHLII_00208 3.3e-211 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IKDGHLII_00209 3.6e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
IKDGHLII_00210 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
IKDGHLII_00211 1.5e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKDGHLII_00213 2.7e-35 K SpoVT / AbrB like domain
IKDGHLII_00214 1.3e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
IKDGHLII_00215 5.7e-124 S ABC-2 type transporter
IKDGHLII_00216 5e-139 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
IKDGHLII_00217 8.4e-30
IKDGHLII_00218 0.0 yjcD 3.6.4.12 L DNA helicase
IKDGHLII_00219 3.8e-38 spoVIF S Stage VI sporulation protein F
IKDGHLII_00223 5.6e-56 yjcA S Protein of unknown function (DUF1360)
IKDGHLII_00224 1.4e-52 cotV S Spore Coat Protein X and V domain
IKDGHLII_00225 6.8e-21 cotW
IKDGHLII_00226 5.1e-71 cotX S Spore Coat Protein X and V domain
IKDGHLII_00227 4.6e-93 cotY S Spore coat protein Z
IKDGHLII_00228 6.7e-83 cotZ S Spore coat protein
IKDGHLII_00229 1.2e-87 yjbX S Spore coat protein
IKDGHLII_00230 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IKDGHLII_00231 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IKDGHLII_00232 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IKDGHLII_00233 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IKDGHLII_00234 6.7e-30 thiS H Thiamine biosynthesis
IKDGHLII_00235 3e-209 thiO 1.4.3.19 E Glycine oxidase
IKDGHLII_00236 2.1e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
IKDGHLII_00237 3.7e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IKDGHLII_00238 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IKDGHLII_00239 2.8e-142 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IKDGHLII_00240 3.7e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IKDGHLII_00241 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IKDGHLII_00242 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
IKDGHLII_00243 6e-61 yjbL S Belongs to the UPF0738 family
IKDGHLII_00244 4e-96 yjbK S protein conserved in bacteria
IKDGHLII_00245 1.6e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IKDGHLII_00246 4.8e-72 yjbI S Bacterial-like globin
IKDGHLII_00247 6.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IKDGHLII_00248 5.8e-19
IKDGHLII_00249 0.0 pepF E oligoendopeptidase F
IKDGHLII_00250 9.3e-217 yjbF S Competence protein
IKDGHLII_00251 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IKDGHLII_00252 4.7e-109 yjbE P Integral membrane protein TerC family
IKDGHLII_00253 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IKDGHLII_00254 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKDGHLII_00255 9.8e-230 S Putative glycosyl hydrolase domain
IKDGHLII_00256 2.3e-170 oppF E Belongs to the ABC transporter superfamily
IKDGHLII_00257 2.7e-202 oppD P Belongs to the ABC transporter superfamily
IKDGHLII_00258 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKDGHLII_00259 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKDGHLII_00260 0.0 oppA E ABC transporter substrate-binding protein
IKDGHLII_00261 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IKDGHLII_00262 1.2e-145 yjbA S Belongs to the UPF0736 family
IKDGHLII_00263 2.1e-140 EGP Transmembrane secretion effector
IKDGHLII_00264 1.7e-86 2.1.1.265 H Tellurite resistance protein TehB
IKDGHLII_00265 6.1e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKDGHLII_00266 1.2e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKDGHLII_00267 4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
IKDGHLII_00268 3.8e-187 appF E Belongs to the ABC transporter superfamily
IKDGHLII_00269 4.8e-182 appD P Belongs to the ABC transporter superfamily
IKDGHLII_00270 5.6e-149 yjaZ O Zn-dependent protease
IKDGHLII_00271 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IKDGHLII_00272 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IKDGHLII_00273 5.4e-25 yjzB
IKDGHLII_00274 1.1e-26 comZ S ComZ
IKDGHLII_00275 8e-165 med S Transcriptional activator protein med
IKDGHLII_00276 8.8e-104 yjaV
IKDGHLII_00277 8.4e-139 yjaU I carboxylic ester hydrolase activity
IKDGHLII_00278 3.3e-23 yjzD S Protein of unknown function (DUF2929)
IKDGHLII_00279 3.6e-27 yjzC S YjzC-like protein
IKDGHLII_00280 6.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IKDGHLII_00281 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
IKDGHLII_00282 1.3e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IKDGHLII_00283 1.9e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IKDGHLII_00284 1.4e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
IKDGHLII_00285 1.1e-225 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IKDGHLII_00286 2.1e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IKDGHLII_00287 1.2e-89 norB G Major Facilitator Superfamily
IKDGHLII_00288 1.5e-272 yitY C D-arabinono-1,4-lactone oxidase
IKDGHLII_00289 4.6e-73 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IKDGHLII_00290 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
IKDGHLII_00291 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IKDGHLII_00292 5.1e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IKDGHLII_00293 3.5e-07
IKDGHLII_00294 4.4e-26 S Protein of unknown function (DUF3813)
IKDGHLII_00295 5.5e-80 ipi S Intracellular proteinase inhibitor
IKDGHLII_00296 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
IKDGHLII_00297 4.6e-157 yitS S protein conserved in bacteria
IKDGHLII_00299 3.7e-227 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
IKDGHLII_00300 2.2e-171 yufN S ABC transporter substrate-binding protein PnrA-like
IKDGHLII_00301 2.2e-159 cvfB S protein conserved in bacteria
IKDGHLII_00302 6.6e-55 yajQ S Belongs to the UPF0234 family
IKDGHLII_00303 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IKDGHLII_00304 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
IKDGHLII_00305 1.7e-68 mcbG S Pentapeptide repeats (9 copies)
IKDGHLII_00306 3.4e-83 yisT S DinB family
IKDGHLII_00307 5.8e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
IKDGHLII_00308 4.1e-144 purR K helix_turn _helix lactose operon repressor
IKDGHLII_00309 2.3e-159 yisR K Transcriptional regulator
IKDGHLII_00310 1.5e-245 yisQ V Mate efflux family protein
IKDGHLII_00311 1.9e-130 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
IKDGHLII_00312 0.0 asnO 6.3.5.4 E Asparagine synthase
IKDGHLII_00313 3.4e-97 yisN S Protein of unknown function (DUF2777)
IKDGHLII_00314 3.2e-59 yisL S UPF0344 protein
IKDGHLII_00315 1.3e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IKDGHLII_00316 4.8e-07 yisI S Spo0E like sporulation regulatory protein
IKDGHLII_00317 8.4e-34 gerPA S Spore germination protein
IKDGHLII_00318 1.8e-34 gerPB S cell differentiation
IKDGHLII_00319 1.4e-62 gerPC S Spore germination protein
IKDGHLII_00320 3.1e-23 gerPD S Spore germination protein
IKDGHLII_00321 1.1e-63 gerPE S Spore germination protein GerPE
IKDGHLII_00322 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
IKDGHLII_00323 5e-50 yisB V COG1403 Restriction endonuclease
IKDGHLII_00324 0.0 sbcC L COG0419 ATPase involved in DNA repair
IKDGHLII_00325 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IKDGHLII_00326 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IKDGHLII_00327 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
IKDGHLII_00328 2.5e-119 ydfS S Protein of unknown function (DUF421)
IKDGHLII_00329 6.3e-93 yhjR S Rubrerythrin
IKDGHLII_00330 1.1e-107 K QacR-like protein, C-terminal region
IKDGHLII_00331 3e-202 blt EGP Major facilitator Superfamily
IKDGHLII_00332 1.8e-188 abrB S membrane
IKDGHLII_00333 8.4e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
IKDGHLII_00334 2.1e-269 yhjG CH FAD binding domain
IKDGHLII_00336 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
IKDGHLII_00337 7.7e-109 yhjE S SNARE associated Golgi protein
IKDGHLII_00338 1.7e-60 yhjD
IKDGHLII_00339 3.1e-27 yhjC S Protein of unknown function (DUF3311)
IKDGHLII_00340 3.8e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IKDGHLII_00341 5.6e-47 S Belongs to the UPF0145 family
IKDGHLII_00342 1.6e-42 yhjA S Excalibur calcium-binding domain
IKDGHLII_00343 8.7e-125 yrpD S Domain of unknown function, YrpD
IKDGHLII_00344 4.2e-62 frataxin S Domain of unknown function (DU1801)
IKDGHLII_00345 4.7e-66 frataxin S Domain of unknown function (DU1801)
IKDGHLII_00346 1.9e-109 comK K Competence transcription factor
IKDGHLII_00347 5.4e-31 yhzC S IDEAL
IKDGHLII_00348 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKDGHLII_00349 1e-295 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
IKDGHLII_00350 3.1e-197 hemAT NT chemotaxis protein
IKDGHLII_00351 3.5e-89 bioY S BioY family
IKDGHLII_00352 1.6e-279 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IKDGHLII_00353 9.7e-200 vraB 2.3.1.9 I Belongs to the thiolase family
IKDGHLII_00354 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IKDGHLII_00355 5.1e-151 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IKDGHLII_00356 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
IKDGHLII_00357 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
IKDGHLII_00358 1.9e-65 yhfM
IKDGHLII_00359 4.1e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IKDGHLII_00360 2.7e-109 yhfK GM NmrA-like family
IKDGHLII_00361 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
IKDGHLII_00362 2.2e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IKDGHLII_00363 7.9e-11 yhfH S YhfH-like protein
IKDGHLII_00364 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IKDGHLII_00365 2.5e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
IKDGHLII_00367 9.6e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IKDGHLII_00368 4.3e-42 L transposase activity
IKDGHLII_00369 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
IKDGHLII_00370 7.2e-245 yhgE S YhgE Pip N-terminal domain protein
IKDGHLII_00371 3.2e-101 yhgD K Transcriptional regulator
IKDGHLII_00372 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IKDGHLII_00373 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IKDGHLII_00374 3.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IKDGHLII_00375 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IKDGHLII_00376 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IKDGHLII_00377 8.1e-244 yhfA C membrane
IKDGHLII_00378 2e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IKDGHLII_00379 4e-122 ecsC S EcsC protein family
IKDGHLII_00380 1.5e-220 ecsB U ABC transporter
IKDGHLII_00381 1.1e-135 ecsA V transporter (ATP-binding protein)
IKDGHLII_00382 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IKDGHLII_00383 6e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IKDGHLII_00384 1.4e-76 trpP S Tryptophan transporter TrpP
IKDGHLII_00385 2e-17
IKDGHLII_00386 6.2e-39 yhaH S YtxH-like protein
IKDGHLII_00387 8.6e-113 hpr K Negative regulator of protease production and sporulation
IKDGHLII_00388 9.9e-55 yhaI S Protein of unknown function (DUF1878)
IKDGHLII_00389 7e-95 yhaK S Putative zincin peptidase
IKDGHLII_00390 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IKDGHLII_00391 1.8e-31 yhaL S Sporulation protein YhaL
IKDGHLII_00392 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
IKDGHLII_00393 0.0 yhaN L AAA domain
IKDGHLII_00394 4.7e-235 yhaO L DNA repair exonuclease
IKDGHLII_00395 2.7e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
IKDGHLII_00396 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
IKDGHLII_00397 2.8e-14 S YhzD-like protein
IKDGHLII_00398 2e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
IKDGHLII_00400 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
IKDGHLII_00401 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
IKDGHLII_00402 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
IKDGHLII_00403 2.7e-293 hemZ H coproporphyrinogen III oxidase
IKDGHLII_00404 4.7e-157 yhaX S haloacid dehalogenase-like hydrolase
IKDGHLII_00405 5.9e-200 yhaZ L DNA alkylation repair enzyme
IKDGHLII_00406 4.4e-53 yheA S Belongs to the UPF0342 family
IKDGHLII_00407 3.6e-205 yheB S Belongs to the UPF0754 family
IKDGHLII_00408 3.4e-213 yheC HJ YheC/D like ATP-grasp
IKDGHLII_00409 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
IKDGHLII_00410 2.2e-36 yheE S Family of unknown function (DUF5342)
IKDGHLII_00411 1.3e-28 sspB S spore protein
IKDGHLII_00413 6.2e-111 yheG GM NAD(P)H-binding
IKDGHLII_00414 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
IKDGHLII_00415 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
IKDGHLII_00417 6.2e-85 T universal stress protein
IKDGHLII_00418 4e-93 ymcC S Membrane
IKDGHLII_00419 3e-87 pksA K Transcriptional regulator
IKDGHLII_00420 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IKDGHLII_00421 1.1e-155 yheN G deacetylase
IKDGHLII_00422 1.2e-137 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IKDGHLII_00423 3.5e-205 yhdY M Mechanosensitive ion channel
IKDGHLII_00425 7.2e-127 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IKDGHLII_00426 4.3e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IKDGHLII_00427 2.1e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IKDGHLII_00428 1.3e-254 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
IKDGHLII_00429 1.1e-234 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IKDGHLII_00430 1.9e-225 yhdR 2.6.1.1 E Aminotransferase
IKDGHLII_00431 2.8e-70 cueR K transcriptional
IKDGHLII_00432 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IKDGHLII_00433 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IKDGHLII_00434 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
IKDGHLII_00435 1.3e-201 yhdL S Sigma factor regulator N-terminal
IKDGHLII_00436 8.1e-45 yhdK S Sigma-M inhibitor protein
IKDGHLII_00437 3e-195 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IKDGHLII_00438 1.2e-250 yhdG E amino acid
IKDGHLII_00439 2.3e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKDGHLII_00440 4.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
IKDGHLII_00441 1.3e-162 citR K Transcriptional regulator
IKDGHLII_00442 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IKDGHLII_00443 1.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
IKDGHLII_00444 1.8e-270 ycgB S Stage V sporulation protein R
IKDGHLII_00445 3.8e-255 ygxB M Conserved TM helix
IKDGHLII_00446 1.6e-73 nsrR K Transcriptional regulator
IKDGHLII_00447 1.1e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IKDGHLII_00448 5.3e-53 yhdC S Protein of unknown function (DUF3889)
IKDGHLII_00449 2.5e-39 yhdB S YhdB-like protein
IKDGHLII_00450 3.3e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
IKDGHLII_00451 4.3e-37 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKDGHLII_00452 8.5e-70 yhcY 2.7.13.3 T Histidine kinase
IKDGHLII_00453 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IKDGHLII_00454 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IKDGHLII_00455 1.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IKDGHLII_00456 6.5e-148 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
IKDGHLII_00457 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IKDGHLII_00458 7.8e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IKDGHLII_00459 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IKDGHLII_00460 4.9e-125 yhcW 5.4.2.6 S hydrolase
IKDGHLII_00461 9.9e-68 yhcV S COG0517 FOG CBS domain
IKDGHLII_00462 1.3e-69 yhcU S Family of unknown function (DUF5365)
IKDGHLII_00463 4e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IKDGHLII_00464 2.2e-105 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
IKDGHLII_00465 3.7e-10 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
IKDGHLII_00466 7.3e-60 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
IKDGHLII_00467 8.4e-114 yhcQ M Spore coat protein
IKDGHLII_00468 3.2e-159 yhcP
IKDGHLII_00469 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IKDGHLII_00470 2.3e-47 yhcM
IKDGHLII_00471 1.1e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IKDGHLII_00472 2.5e-184 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
IKDGHLII_00473 1.7e-143 metQ M Belongs to the nlpA lipoprotein family
IKDGHLII_00474 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
IKDGHLII_00475 1.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IKDGHLII_00476 2.6e-166 yhcH V ABC transporter, ATP-binding protein
IKDGHLII_00477 4.8e-123 yhcG V ABC transporter, ATP-binding protein
IKDGHLII_00478 3.6e-61 yhcF K Transcriptional regulator
IKDGHLII_00479 1.6e-52
IKDGHLII_00480 3.8e-55 yhcC
IKDGHLII_00481 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
IKDGHLII_00482 8.4e-285 yhcA EGP Major facilitator Superfamily
IKDGHLII_00483 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
IKDGHLII_00484 4.6e-74 yhbI K DNA-binding transcription factor activity
IKDGHLII_00485 3.9e-215 yhbH S Belongs to the UPF0229 family
IKDGHLII_00486 0.0 prkA T Ser protein kinase
IKDGHLII_00488 9.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
IKDGHLII_00489 8.9e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
IKDGHLII_00490 3e-108 yhbD K Protein of unknown function (DUF4004)
IKDGHLII_00491 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IKDGHLII_00492 2e-172 yhbB S Putative amidase domain
IKDGHLII_00493 1.7e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IKDGHLII_00494 3.2e-107 yhzB S B3/4 domain
IKDGHLII_00496 4.8e-23 K Transcriptional regulator
IKDGHLII_00497 8.6e-81 ygaO
IKDGHLII_00498 1.6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IKDGHLII_00499 3.8e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
IKDGHLII_00500 3.7e-143 ssuC P ABC transporter (permease)
IKDGHLII_00501 1.7e-179 ssuA M Sulfonate ABC transporter
IKDGHLII_00502 1.8e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IKDGHLII_00503 6.6e-181 S Amidohydrolase
IKDGHLII_00504 1e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IKDGHLII_00505 5.3e-133 oppF3 E Belongs to the ABC transporter superfamily
IKDGHLII_00506 1.3e-134 oppD3 P Belongs to the ABC transporter superfamily
IKDGHLII_00507 1.2e-126 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IKDGHLII_00508 9.2e-138 appB P Binding-protein-dependent transport system inner membrane component
IKDGHLII_00509 3.4e-231 oppA5 E PFAM extracellular solute-binding protein family 5
IKDGHLII_00511 5.9e-263 ygaK C Berberine and berberine like
IKDGHLII_00512 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IKDGHLII_00513 1.6e-28 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
IKDGHLII_00514 5.3e-90 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
IKDGHLII_00515 2.9e-19 C Na+/H+ antiporter family
IKDGHLII_00519 1.6e-08
IKDGHLII_00527 7.8e-08
IKDGHLII_00532 3.4e-39 S COG NOG14552 non supervised orthologous group
IKDGHLII_00533 1.1e-164 ygxA S Nucleotidyltransferase-like
IKDGHLII_00534 1.5e-56 ygzB S UPF0295 protein
IKDGHLII_00535 1.8e-80 perR P Belongs to the Fur family
IKDGHLII_00536 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
IKDGHLII_00537 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IKDGHLII_00538 2.7e-178 ygaE S Membrane
IKDGHLII_00539 3.5e-300 ygaD V ABC transporter
IKDGHLII_00540 2.2e-104 ygaC J Belongs to the UPF0374 family
IKDGHLII_00541 1.5e-37 ygaB S YgaB-like protein
IKDGHLII_00543 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKDGHLII_00544 3.1e-36 yfhS
IKDGHLII_00545 4.8e-207 mutY L A G-specific
IKDGHLII_00546 8.8e-185 yfhP S membrane-bound metal-dependent
IKDGHLII_00547 0.0 yfhO S Bacterial membrane protein YfhO
IKDGHLII_00548 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IKDGHLII_00549 1.2e-168 yfhM S Alpha/beta hydrolase family
IKDGHLII_00550 9.7e-34 yfhL S SdpI/YhfL protein family
IKDGHLII_00551 8.5e-93 batE T Bacterial SH3 domain homologues
IKDGHLII_00552 2.2e-44 yfhJ S WVELL protein
IKDGHLII_00553 5.3e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
IKDGHLII_00555 1.1e-204 yfhI EGP Major facilitator Superfamily
IKDGHLII_00556 2.5e-52 yfhH S Protein of unknown function (DUF1811)
IKDGHLII_00557 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
IKDGHLII_00558 3.4e-166 yfhF S nucleoside-diphosphate sugar epimerase
IKDGHLII_00560 6.1e-25 yfhD S YfhD-like protein
IKDGHLII_00561 3.3e-106 yfhC C nitroreductase
IKDGHLII_00562 7.2e-161 yfhB 5.3.3.17 S PhzF family
IKDGHLII_00563 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IKDGHLII_00564 3.1e-81 yfiV K transcriptional
IKDGHLII_00565 1.1e-289 yfiU EGP Major facilitator Superfamily
IKDGHLII_00566 6.9e-98 yfiT S Belongs to the metal hydrolase YfiT family
IKDGHLII_00567 4.5e-45 yrdF K ribonuclease inhibitor
IKDGHLII_00568 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
IKDGHLII_00569 1e-177 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IKDGHLII_00570 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
IKDGHLII_00571 6.6e-96 padR K transcriptional
IKDGHLII_00572 6.1e-166 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IKDGHLII_00573 8.5e-159 yfiE 1.13.11.2 S glyoxalase
IKDGHLII_00574 9.2e-63 mhqP S DoxX
IKDGHLII_00575 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
IKDGHLII_00576 6.2e-310 yfiB3 V ABC transporter
IKDGHLII_00577 3.2e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IKDGHLII_00578 5.1e-139 glvR F Helix-turn-helix domain, rpiR family
IKDGHLII_00579 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IKDGHLII_00580 4.2e-15 sspH S Belongs to the SspH family
IKDGHLII_00581 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
IKDGHLII_00582 4.7e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IKDGHLII_00583 1.2e-211 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IKDGHLII_00584 2.3e-187 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IKDGHLII_00585 6.4e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IKDGHLII_00586 5.7e-88 yfjM S Psort location Cytoplasmic, score
IKDGHLII_00587 3.5e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IKDGHLII_00588 3.3e-43 S YfzA-like protein
IKDGHLII_00589 2.1e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IKDGHLII_00590 2.4e-161 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IKDGHLII_00591 8.5e-184 corA P Mediates influx of magnesium ions
IKDGHLII_00592 1.5e-30
IKDGHLII_00593 5.2e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IKDGHLII_00594 9e-155 pdaA G deacetylase
IKDGHLII_00595 4.9e-27 yfjT
IKDGHLII_00596 9.6e-219 yfkA S YfkB-like domain
IKDGHLII_00597 4e-145 yfkC M Mechanosensitive ion channel
IKDGHLII_00598 1.6e-143 yfkD S YfkD-like protein
IKDGHLII_00599 2.2e-185 cax P COG0387 Ca2 H antiporter
IKDGHLII_00600 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
IKDGHLII_00601 2.5e-07
IKDGHLII_00602 7.6e-144 yihY S Belongs to the UPF0761 family
IKDGHLII_00603 1.7e-51 yfkI S gas vesicle protein
IKDGHLII_00604 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IKDGHLII_00605 2.7e-29 yfkK S Belongs to the UPF0435 family
IKDGHLII_00606 8.1e-192 ydiM EGP Major facilitator Superfamily
IKDGHLII_00607 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IKDGHLII_00608 1.2e-163 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IKDGHLII_00609 9.8e-186 K helix_turn _helix lactose operon repressor
IKDGHLII_00610 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
IKDGHLII_00611 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
IKDGHLII_00612 5.5e-198 yibE S YibE/F-like protein
IKDGHLII_00613 1e-123 yibF S YibE/F-like protein
IKDGHLII_00614 1.2e-123 yfkO C nitroreductase
IKDGHLII_00615 2e-129 treR K transcriptional
IKDGHLII_00616 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IKDGHLII_00617 1.2e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IKDGHLII_00618 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
IKDGHLII_00619 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
IKDGHLII_00620 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
IKDGHLII_00621 2.3e-63 yhdN S Domain of unknown function (DUF1992)
IKDGHLII_00622 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IKDGHLII_00623 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
IKDGHLII_00624 3.3e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IKDGHLII_00625 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
IKDGHLII_00626 3.1e-50 yflH S Protein of unknown function (DUF3243)
IKDGHLII_00627 7e-19 yflI
IKDGHLII_00628 1.5e-14 yflJ S Protein of unknown function (DUF2639)
IKDGHLII_00629 1.3e-122 yflK S protein conserved in bacteria
IKDGHLII_00630 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IKDGHLII_00631 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IKDGHLII_00632 7.4e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
IKDGHLII_00633 3.6e-225 citM C Citrate transporter
IKDGHLII_00634 3e-176 yflP S Tripartite tricarboxylate transporter family receptor
IKDGHLII_00635 2.6e-118 citT T response regulator
IKDGHLII_00636 6.2e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IKDGHLII_00637 4.6e-80 srtA 3.4.22.70 M Sortase family
IKDGHLII_00638 0.0 M1-568 M cell wall anchor domain
IKDGHLII_00639 3.7e-151 M1-574 T Transcriptional regulatory protein, C terminal
IKDGHLII_00640 0.0 ywpD T PhoQ Sensor
IKDGHLII_00641 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
IKDGHLII_00643 5.2e-27 Q PFAM Collagen triple helix
IKDGHLII_00644 6e-234 yflS P Sodium:sulfate symporter transmembrane region
IKDGHLII_00645 2.9e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
IKDGHLII_00646 1.3e-57 yflT S Heat induced stress protein YflT
IKDGHLII_00647 2.7e-24 S Protein of unknown function (DUF3212)
IKDGHLII_00648 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
IKDGHLII_00649 2.1e-41 yfmK 2.3.1.128 K acetyltransferase
IKDGHLII_00650 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
IKDGHLII_00651 3.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IKDGHLII_00652 7.5e-206 yfmO EGP Major facilitator Superfamily
IKDGHLII_00653 1.8e-69 yfmP K transcriptional
IKDGHLII_00654 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IKDGHLII_00655 1.2e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IKDGHLII_00656 5.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
IKDGHLII_00657 7.5e-107 yfmS NT chemotaxis protein
IKDGHLII_00658 1.4e-275 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IKDGHLII_00659 3e-246 yfnA E amino acid
IKDGHLII_00660 6.8e-218 fsr P COG0477 Permeases of the major facilitator superfamily
IKDGHLII_00661 1.5e-185 yfnD M Nucleotide-diphospho-sugar transferase
IKDGHLII_00662 6.2e-221 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
IKDGHLII_00663 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
IKDGHLII_00664 7.1e-172 yfnG 4.2.1.45 M dehydratase
IKDGHLII_00665 1.8e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
IKDGHLII_00666 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IKDGHLII_00667 2.1e-143 2.1.1.163, 2.1.1.201 Q methyltransferase
IKDGHLII_00668 2.8e-112 S CAAX protease self-immunity
IKDGHLII_00669 8.6e-153 sagB C Nitroreductase family
IKDGHLII_00670 1.1e-261 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
IKDGHLII_00671 9.8e-183 S ATP diphosphatase activity
IKDGHLII_00672 6.6e-125
IKDGHLII_00673 1.7e-67 S protein homooligomerization
IKDGHLII_00674 4.8e-126 V ABC-2 type transporter
IKDGHLII_00675 1.5e-161 V ATPases associated with a variety of cellular activities
IKDGHLII_00676 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
IKDGHLII_00678 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IKDGHLII_00679 1.9e-184 yetN S Protein of unknown function (DUF3900)
IKDGHLII_00680 3e-204 yetM CH FAD binding domain
IKDGHLII_00681 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
IKDGHLII_00683 2.2e-103 yetJ S Belongs to the BI1 family
IKDGHLII_00684 5.3e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
IKDGHLII_00685 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
IKDGHLII_00686 3.7e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IKDGHLII_00687 3.2e-07 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKDGHLII_00688 2e-42 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKDGHLII_00689 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IKDGHLII_00690 2.1e-120 yetF S membrane
IKDGHLII_00692 2e-94 yesJ K Acetyltransferase (GNAT) family
IKDGHLII_00693 8.9e-104 cotJC P Spore Coat
IKDGHLII_00694 1.3e-44 cotJB S CotJB protein
IKDGHLII_00695 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
IKDGHLII_00696 9e-108 aadK G Streptomycin adenylyltransferase
IKDGHLII_00698 9.4e-127 yeeN K transcriptional regulatory protein
IKDGHLII_00699 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
IKDGHLII_00700 1.1e-57 S Protein of unknown function, DUF600
IKDGHLII_00701 1.6e-76 S Protein of unknown function, DUF600
IKDGHLII_00702 1.7e-55 S Protein of unknown function, DUF600
IKDGHLII_00703 1.1e-46 S Protein of unknown function, DUF600
IKDGHLII_00704 6.9e-54 S Protein of unknown function, DUF600
IKDGHLII_00705 2.2e-138 cylB V ABC-2 type transporter
IKDGHLII_00706 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
IKDGHLII_00707 4.5e-21
IKDGHLII_00708 1.1e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IKDGHLII_00709 1.9e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IKDGHLII_00710 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IKDGHLII_00711 3.4e-152 yerO K Transcriptional regulator
IKDGHLII_00712 3.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IKDGHLII_00713 3e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IKDGHLII_00714 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IKDGHLII_00715 1.4e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IKDGHLII_00716 1.3e-120 sapB S MgtC SapB transporter
IKDGHLII_00717 7.5e-191 yerI S homoserine kinase type II (protein kinase fold)
IKDGHLII_00718 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
IKDGHLII_00719 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IKDGHLII_00720 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IKDGHLII_00721 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IKDGHLII_00722 4.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
IKDGHLII_00723 2.4e-50 yerC S protein conserved in bacteria
IKDGHLII_00724 1.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
IKDGHLII_00725 0.0 yerA 3.5.4.2 F adenine deaminase
IKDGHLII_00726 2.6e-25 S Protein of unknown function (DUF2892)
IKDGHLII_00727 5.3e-234 purD 6.3.4.13 F Belongs to the GARS family
IKDGHLII_00728 6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IKDGHLII_00729 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IKDGHLII_00730 1.9e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IKDGHLII_00731 1.2e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IKDGHLII_00732 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IKDGHLII_00733 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IKDGHLII_00734 8.4e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IKDGHLII_00735 3.8e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IKDGHLII_00736 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IKDGHLII_00737 1.8e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IKDGHLII_00738 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IKDGHLII_00739 5.5e-29 yebG S NETI protein
IKDGHLII_00740 3.7e-91 yebE S UPF0316 protein
IKDGHLII_00742 1.5e-125 yebC M Membrane
IKDGHLII_00743 8.1e-209 pbuG S permease
IKDGHLII_00744 7.4e-248 S Domain of unknown function (DUF4179)
IKDGHLII_00745 5e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IKDGHLII_00746 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IKDGHLII_00747 0.0 yebA E COG1305 Transglutaminase-like enzymes
IKDGHLII_00748 1.9e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IKDGHLII_00749 3e-176 yeaC S COG0714 MoxR-like ATPases
IKDGHLII_00750 3.1e-243 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
IKDGHLII_00751 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
IKDGHLII_00752 7.2e-35 ydjO S Cold-inducible protein YdjO
IKDGHLII_00754 2e-133 ydjN U Involved in the tonB-independent uptake of proteins
IKDGHLII_00755 1.2e-61 ydjM M Lytic transglycolase
IKDGHLII_00756 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
IKDGHLII_00757 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IKDGHLII_00758 1.4e-145 rsiV S Protein of unknown function (DUF3298)
IKDGHLII_00759 0.0 yrhL I Acyltransferase family
IKDGHLII_00760 2.4e-144 ydjI S virion core protein (lumpy skin disease virus)
IKDGHLII_00761 4.5e-119 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
IKDGHLII_00762 3e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IKDGHLII_00763 1.3e-112 pspA KT Phage shock protein A
IKDGHLII_00764 3.6e-30 yjdJ S Domain of unknown function (DUF4306)
IKDGHLII_00765 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
IKDGHLII_00766 1.9e-248 gutA G MFS/sugar transport protein
IKDGHLII_00767 2.1e-199 gutB 1.1.1.14 E Dehydrogenase
IKDGHLII_00768 0.0 K NB-ARC domain
IKDGHLII_00769 1.7e-33 yvfS V Transporter
IKDGHLII_00770 1.6e-78 yvfR V ABC transporter
IKDGHLII_00771 1e-07 moeB 2.7.7.73, 2.7.7.80 H molybdopterin biosynthesis protein moeB
IKDGHLII_00772 1.8e-28 C Nitroreductase family
IKDGHLII_00773 4.3e-39 cobT 1.13.11.79, 2.4.2.21 C coenzyme F420-1:gamma-L-glutamate ligase activity
IKDGHLII_00774 2e-102 H YcaO cyclodehydratase, ATP-ad Mg2+-binding
IKDGHLII_00776 4.1e-25 C coenzyme F420-1:gamma-L-glutamate ligase activity
IKDGHLII_00777 3.9e-50 S Lantibiotic dehydratase, C terminus
IKDGHLII_00778 9.1e-71 E Peptidase dimerisation domain
IKDGHLII_00779 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IKDGHLII_00780 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IKDGHLII_00781 9.6e-127 ydiL S CAAX protease self-immunity
IKDGHLII_00782 1.7e-27 ydiK S Domain of unknown function (DUF4305)
IKDGHLII_00783 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IKDGHLII_00784 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IKDGHLII_00785 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IKDGHLII_00786 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IKDGHLII_00787 0.0 ydiF S ABC transporter
IKDGHLII_00788 2.1e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IKDGHLII_00789 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IKDGHLII_00790 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
IKDGHLII_00791 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
IKDGHLII_00792 6.7e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IKDGHLII_00794 7.8e-08
IKDGHLII_00795 3.4e-39 S COG NOG14552 non supervised orthologous group
IKDGHLII_00798 1.2e-250 iolT EGP Major facilitator Superfamily
IKDGHLII_00799 1.7e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
IKDGHLII_00800 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
IKDGHLII_00801 5.7e-163 ydhU P Catalase
IKDGHLII_00802 2.1e-296 yveA E amino acid
IKDGHLII_00803 2.9e-102 yvdT K Transcriptional regulator
IKDGHLII_00804 2.3e-51 ykkC P Small Multidrug Resistance protein
IKDGHLII_00805 2.6e-49 sugE P Small Multidrug Resistance protein
IKDGHLII_00806 8.2e-216 yeaN P COG2807 Cyanate permease
IKDGHLII_00807 1.9e-116 K FCD
IKDGHLII_00808 1.3e-131 ydhQ K UTRA
IKDGHLII_00809 3.4e-195 pbuE EGP Major facilitator Superfamily
IKDGHLII_00810 8e-97 ydhK M Protein of unknown function (DUF1541)
IKDGHLII_00812 6.5e-262 pbpE V Beta-lactamase
IKDGHLII_00815 3.5e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IKDGHLII_00816 6.9e-119 ydhC K FCD
IKDGHLII_00817 7.7e-159 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
IKDGHLII_00818 6.4e-145 ycgJ_1 Q ubiE/COQ5 methyltransferase family
IKDGHLII_00819 6.9e-110 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
IKDGHLII_00820 2.9e-146 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IKDGHLII_00821 9e-150 bltR K helix_turn_helix, mercury resistance
IKDGHLII_00822 2.2e-81 bltD 2.3.1.57 K FR47-like protein
IKDGHLII_00823 9.4e-122 ydhB S membrane transporter protein
IKDGHLII_00824 1.9e-155 K Helix-turn-helix XRE-family like proteins
IKDGHLII_00825 1.1e-223 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IKDGHLII_00826 3.9e-210 tcaB EGP Major facilitator Superfamily
IKDGHLII_00827 5e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
IKDGHLII_00828 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
IKDGHLII_00829 5.7e-97 ynaD J Acetyltransferase (GNAT) domain
IKDGHLII_00830 5.2e-298 expZ S ABC transporter
IKDGHLII_00831 3.3e-132 puuD S Peptidase C26
IKDGHLII_00832 0.0 ydfJ S drug exporters of the RND superfamily
IKDGHLII_00833 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKDGHLII_00834 1.3e-151 ydfH 2.7.13.3 T Histidine kinase
IKDGHLII_00835 4.9e-35 yraG
IKDGHLII_00836 8.4e-63 yraF M Spore coat protein
IKDGHLII_00837 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IKDGHLII_00838 5.4e-24 yraE
IKDGHLII_00839 1.4e-47 yraD M Spore coat protein
IKDGHLII_00840 1.2e-100 ydeS K Transcriptional regulator
IKDGHLII_00841 1.2e-179 ydeR EGP Major facilitator Superfamily
IKDGHLII_00843 3.3e-112 paiB K Transcriptional regulator
IKDGHLII_00844 3.2e-256 K helix_turn_helix gluconate operon transcriptional repressor
IKDGHLII_00845 2.3e-224 mleN_2 C antiporter
IKDGHLII_00846 8e-67 yraB K helix_turn_helix, mercury resistance
IKDGHLII_00847 3.8e-201 adhA 1.1.1.1 C alcohol dehydrogenase
IKDGHLII_00848 2.6e-164 S Sodium Bile acid symporter family
IKDGHLII_00849 5.9e-51 ydeH
IKDGHLII_00850 7.3e-100 yrkC G Cupin domain
IKDGHLII_00851 4e-195 trkA P Oxidoreductase
IKDGHLII_00852 1.1e-167 czcD P COG1230 Co Zn Cd efflux system component
IKDGHLII_00853 6.6e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
IKDGHLII_00856 5.5e-28 3.6.1.55 F Belongs to the Nudix hydrolase family
IKDGHLII_00857 2.6e-191 ydeG EGP Major facilitator superfamily
IKDGHLII_00858 6.5e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKDGHLII_00859 1.5e-175 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IKDGHLII_00860 7.6e-126 rhaS5 K helix_turn_helix, arabinose operon control protein
IKDGHLII_00861 2.6e-163 E Peptidase dimerisation domain
IKDGHLII_00862 2.2e-142 sdaC E Serine transporter
IKDGHLII_00863 1.7e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
IKDGHLII_00864 2.7e-67 K COG1802 Transcriptional regulators
IKDGHLII_00865 2.5e-116 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
IKDGHLII_00866 4.2e-83 S DinB superfamily
IKDGHLII_00867 2.6e-180 S Patatin-like phospholipase
IKDGHLII_00868 2.4e-50 K Transcriptional regulator PadR-like family
IKDGHLII_00869 9.8e-103 S Protein of unknown function (DUF2812)
IKDGHLII_00870 3.7e-117 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IKDGHLII_00871 7.3e-117 yrkJ S membrane transporter protein
IKDGHLII_00872 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
IKDGHLII_00873 1.5e-200 yrkH P Rhodanese Homology Domain
IKDGHLII_00874 5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
IKDGHLII_00875 2.2e-17 P Rhodanese Homology Domain
IKDGHLII_00876 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
IKDGHLII_00877 9.2e-40 yrkD S protein conserved in bacteria
IKDGHLII_00878 1.4e-30 cspL K Cold shock
IKDGHLII_00879 5.4e-110 ywnB S NAD(P)H-binding
IKDGHLII_00880 1.6e-71 ywnA K Transcriptional regulator
IKDGHLII_00881 8.2e-49 ohrR K Transcriptional regulator
IKDGHLII_00882 4.8e-46 ohrB O OsmC-like protein
IKDGHLII_00883 1e-136 I esterase
IKDGHLII_00884 9.8e-229 proP EGP Transporter
IKDGHLII_00885 2.3e-150 S Serine aminopeptidase, S33
IKDGHLII_00886 1.1e-95 ywrO S Flavodoxin-like fold
IKDGHLII_00894 8.6e-59 ydcK S Belongs to the SprT family
IKDGHLII_00895 1.7e-14
IKDGHLII_00896 0.0 yhgF K COG2183 Transcriptional accessory protein
IKDGHLII_00897 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
IKDGHLII_00898 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKDGHLII_00899 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IKDGHLII_00900 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
IKDGHLII_00901 1.7e-187 rsbU 3.1.3.3 KT phosphatase
IKDGHLII_00902 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IKDGHLII_00903 1.8e-57 rsbS T antagonist
IKDGHLII_00904 2.3e-145 rsbR T Positive regulator of sigma-B
IKDGHLII_00905 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
IKDGHLII_00906 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IKDGHLII_00907 5.8e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IKDGHLII_00908 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
IKDGHLII_00909 1.5e-56 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IKDGHLII_00910 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
IKDGHLII_00911 6.5e-260 ydbT S Membrane
IKDGHLII_00912 1.3e-60 ydbS S Bacterial PH domain
IKDGHLII_00913 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IKDGHLII_00914 1e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IKDGHLII_00915 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IKDGHLII_00916 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IKDGHLII_00917 5.3e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IKDGHLII_00918 5.8e-09 S Fur-regulated basic protein A
IKDGHLII_00919 1.5e-10 S Fur-regulated basic protein B
IKDGHLII_00920 6.8e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
IKDGHLII_00921 4.6e-52 ydbL
IKDGHLII_00922 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IKDGHLII_00923 6.1e-171 ydbJ V ABC transporter, ATP-binding protein
IKDGHLII_00924 4e-158 ydbI S AI-2E family transporter
IKDGHLII_00925 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IKDGHLII_00926 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
IKDGHLII_00927 3.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IKDGHLII_00928 6.5e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IKDGHLII_00929 1.2e-154 ydbD P Catalase
IKDGHLII_00930 8.5e-60 ydbC S Domain of unknown function (DUF4937
IKDGHLII_00931 1.1e-56 ydbB G Cupin domain
IKDGHLII_00933 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
IKDGHLII_00934 7.8e-53 yvaE P Small Multidrug Resistance protein
IKDGHLII_00935 3.7e-72 yvaD S Family of unknown function (DUF5360)
IKDGHLII_00936 6.5e-34 ydaT
IKDGHLII_00938 2.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
IKDGHLII_00939 1.8e-38
IKDGHLII_00940 2.5e-96
IKDGHLII_00941 5.5e-74
IKDGHLII_00943 7.2e-12
IKDGHLII_00944 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IKDGHLII_00945 6.3e-73 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IKDGHLII_00946 0.0 ydaO E amino acid
IKDGHLII_00947 0.0 ydaN S Bacterial cellulose synthase subunit
IKDGHLII_00948 7.2e-231 ydaM M Glycosyl transferase family group 2
IKDGHLII_00949 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
IKDGHLII_00950 9.6e-147 ydaK T Diguanylate cyclase, GGDEF domain
IKDGHLII_00951 8.7e-201 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
IKDGHLII_00952 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IKDGHLII_00953 4.3e-74 lrpC K Transcriptional regulator
IKDGHLII_00954 1.3e-47 ydzA EGP Major facilitator Superfamily
IKDGHLII_00955 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IKDGHLII_00956 1.4e-77 ydaG 1.4.3.5 S general stress protein
IKDGHLII_00957 3.2e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IKDGHLII_00958 6.6e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
IKDGHLII_00959 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKDGHLII_00960 5.5e-286 ydaB IQ acyl-CoA ligase
IKDGHLII_00961 0.0 mtlR K transcriptional regulator, MtlR
IKDGHLII_00962 1.1e-172 ydhF S Oxidoreductase
IKDGHLII_00963 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
IKDGHLII_00964 5.1e-56 yczJ S biosynthesis
IKDGHLII_00966 3e-116 ycsK E anatomical structure formation involved in morphogenesis
IKDGHLII_00967 3.7e-129 kipR K Transcriptional regulator
IKDGHLII_00968 1.2e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
IKDGHLII_00969 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
IKDGHLII_00970 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
IKDGHLII_00971 5.7e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
IKDGHLII_00972 1e-139 ycsF S Belongs to the UPF0271 (lamB) family
IKDGHLII_00973 1.8e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IKDGHLII_00975 6.6e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IKDGHLII_00976 1.2e-205 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
IKDGHLII_00977 5.2e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IKDGHLII_00978 1.5e-224 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
IKDGHLII_00979 1.6e-55
IKDGHLII_00980 9.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
IKDGHLII_00981 1.1e-297 ycnJ P protein, homolog of Cu resistance protein CopC
IKDGHLII_00982 2.3e-97 ycnI S protein conserved in bacteria
IKDGHLII_00983 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKDGHLII_00984 3.6e-149 glcU U Glucose uptake
IKDGHLII_00985 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IKDGHLII_00986 3.2e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IKDGHLII_00987 4.4e-261 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKDGHLII_00988 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
IKDGHLII_00989 1e-44 ycnE S Monooxygenase
IKDGHLII_00990 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
IKDGHLII_00991 3e-151 ycnC K Transcriptional regulator
IKDGHLII_00992 1.2e-245 ycnB EGP Major facilitator Superfamily
IKDGHLII_00993 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
IKDGHLII_00994 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
IKDGHLII_00995 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKDGHLII_00996 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKDGHLII_00997 3.8e-246 lysC 2.7.2.4 E Belongs to the aspartokinase family
IKDGHLII_00999 1.6e-80 S aspartate phosphatase
IKDGHLII_01000 4.1e-259 T PhoQ Sensor
IKDGHLII_01001 1.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKDGHLII_01002 1e-228 yclI V ABC transporter (permease) YclI
IKDGHLII_01003 1.6e-120 yclH P ABC transporter
IKDGHLII_01004 1.9e-250 yxeQ S MmgE/PrpD family
IKDGHLII_01005 6.4e-218 yxeP 3.5.1.47 E hydrolase activity
IKDGHLII_01006 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
IKDGHLII_01007 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
IKDGHLII_01008 2.1e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
IKDGHLII_01009 1.1e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKDGHLII_01010 3.7e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKDGHLII_01011 1.1e-195 gerKB F Spore germination protein
IKDGHLII_01012 5.2e-234 gerKC S spore germination
IKDGHLII_01013 7.8e-294 gerKA EG Spore germination protein
IKDGHLII_01015 9.2e-277 yclG M Pectate lyase superfamily protein
IKDGHLII_01016 9.2e-270 dtpT E amino acid peptide transporter
IKDGHLII_01017 8.3e-76 yclD
IKDGHLII_01018 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
IKDGHLII_01019 3.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IKDGHLII_01020 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IKDGHLII_01021 3.9e-159 bsdA K LysR substrate binding domain
IKDGHLII_01022 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IKDGHLII_01023 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
IKDGHLII_01024 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IKDGHLII_01025 1.7e-108 yczE S membrane
IKDGHLII_01026 6.1e-128 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IKDGHLII_01027 3e-248 bamJ E Aminotransferase class I and II
IKDGHLII_01028 3.4e-140 srfAD Q thioesterase
IKDGHLII_01029 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
IKDGHLII_01030 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_01031 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_01032 2.6e-61 hxlR K transcriptional
IKDGHLII_01033 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
IKDGHLII_01034 1.6e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
IKDGHLII_01035 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
IKDGHLII_01036 1.5e-65 nin S Competence protein J (ComJ)
IKDGHLII_01037 9e-11 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IKDGHLII_01038 1.3e-48 S Protein of unknown function (DUF2680)
IKDGHLII_01039 3.1e-72 yckC S membrane
IKDGHLII_01040 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IKDGHLII_01041 2.3e-226 yciC S GTPases (G3E family)
IKDGHLII_01042 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IKDGHLII_01043 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
IKDGHLII_01044 6.4e-276 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IKDGHLII_01045 4.9e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IKDGHLII_01046 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
IKDGHLII_01047 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IKDGHLII_01048 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IKDGHLII_01049 8.7e-170 ycgM E Proline dehydrogenase
IKDGHLII_01050 8.9e-147 ycgL S Predicted nucleotidyltransferase
IKDGHLII_01051 6.5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
IKDGHLII_01052 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IKDGHLII_01053 1.2e-220 G COG0477 Permeases of the major facilitator superfamily
IKDGHLII_01054 2.5e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
IKDGHLII_01055 3.1e-107 tmrB S AAA domain
IKDGHLII_01057 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IKDGHLII_01058 1.3e-113 ycgI S Domain of unknown function (DUF1989)
IKDGHLII_01059 6.4e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
IKDGHLII_01060 2.2e-150 yqcI S YqcI/YcgG family
IKDGHLII_01061 4.7e-114 ycgF E Lysine exporter protein LysE YggA
IKDGHLII_01062 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
IKDGHLII_01063 8.1e-261 mdr EGP Major facilitator Superfamily
IKDGHLII_01064 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IKDGHLII_01065 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
IKDGHLII_01066 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
IKDGHLII_01067 4.3e-42 L transposase activity
IKDGHLII_01068 1.5e-80 ycgB
IKDGHLII_01069 2.5e-227 ycgA S Membrane
IKDGHLII_01070 2.8e-210 amhX S amidohydrolase
IKDGHLII_01071 1.5e-163 opuAC E glycine betaine
IKDGHLII_01072 1.6e-138 opuAB P glycine betaine
IKDGHLII_01073 3.9e-229 proV 3.6.3.32 E glycine betaine
IKDGHLII_01074 9e-215 naiP P Uncharacterised MFS-type transporter YbfB
IKDGHLII_01075 2.3e-193 yceH P Belongs to the TelA family
IKDGHLII_01076 0.0 yceG S Putative component of 'biosynthetic module'
IKDGHLII_01077 9.7e-138 terC P Protein of unknown function (DUF475)
IKDGHLII_01078 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
IKDGHLII_01079 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
IKDGHLII_01080 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
IKDGHLII_01081 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKDGHLII_01082 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IKDGHLII_01083 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IKDGHLII_01084 6.7e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
IKDGHLII_01085 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
IKDGHLII_01086 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
IKDGHLII_01087 1e-188 S response regulator aspartate phosphatase
IKDGHLII_01088 1.7e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
IKDGHLII_01089 1.3e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
IKDGHLII_01090 8.7e-254 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
IKDGHLII_01091 4.4e-175 ycdA S Domain of unknown function (DUF5105)
IKDGHLII_01092 1.8e-170 yccK C Aldo keto reductase
IKDGHLII_01093 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
IKDGHLII_01094 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
IKDGHLII_01095 1.9e-195 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IKDGHLII_01096 1e-99 yxaF K Transcriptional regulator
IKDGHLII_01097 1e-241 lmrB EGP the major facilitator superfamily
IKDGHLII_01098 1.1e-203 ycbU E Selenocysteine lyase
IKDGHLII_01099 3.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IKDGHLII_01100 1.4e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IKDGHLII_01101 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IKDGHLII_01102 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
IKDGHLII_01103 5.3e-77 sleB 3.5.1.28 M Cell wall
IKDGHLII_01104 5.6e-62 ycbP S Protein of unknown function (DUF2512)
IKDGHLII_01105 1.6e-55 traF CO Thioredoxin
IKDGHLII_01106 1.5e-62 mhqP S DoxX
IKDGHLII_01107 1.3e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
IKDGHLII_01108 4.5e-109 ydfN C nitroreductase
IKDGHLII_01109 5e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IKDGHLII_01110 1.2e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
IKDGHLII_01111 4.6e-48 ycbJ S Macrolide 2'-phosphotransferase
IKDGHLII_01112 3.4e-68 ycbJ S Macrolide 2'-phosphotransferase
IKDGHLII_01113 7.4e-172 glnL T Regulator
IKDGHLII_01114 2.5e-207 phoQ 2.7.13.3 T Histidine kinase
IKDGHLII_01115 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
IKDGHLII_01116 2.7e-258 agcS E Sodium alanine symporter
IKDGHLII_01117 6.3e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
IKDGHLII_01118 5.2e-257 mmuP E amino acid
IKDGHLII_01119 5.5e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IKDGHLII_01120 1.3e-213 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IKDGHLII_01121 2.5e-191 yceA S Belongs to the UPF0176 family
IKDGHLII_01122 2.7e-42 ybfN
IKDGHLII_01123 4.7e-151 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IKDGHLII_01124 1.9e-86 ybfM S SNARE associated Golgi protein
IKDGHLII_01125 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IKDGHLII_01126 2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IKDGHLII_01127 1.3e-193 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
IKDGHLII_01128 1.2e-82 K Helix-turn-helix XRE-family like proteins
IKDGHLII_01129 9.2e-32
IKDGHLII_01130 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
IKDGHLII_01132 1.6e-210 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
IKDGHLII_01133 1e-16 S Protein of unknown function (DUF2651)
IKDGHLII_01134 1.7e-259 glpT G -transporter
IKDGHLII_01135 3.7e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IKDGHLII_01136 5.5e-292 ybeC E amino acid
IKDGHLII_01137 9.2e-40 ybyB
IKDGHLII_01138 2.3e-106 yqeB
IKDGHLII_01139 7.5e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
IKDGHLII_01140 8.5e-76 S Domain of unknown function (DUF4879)
IKDGHLII_01141 9.2e-23
IKDGHLII_01142 1.4e-193 V ABC-2 family transporter protein
IKDGHLII_01143 6e-203 V COG0842 ABC-type multidrug transport system, permease component
IKDGHLII_01144 3e-165 V COG1131 ABC-type multidrug transport system, ATPase component
IKDGHLII_01145 3.2e-110 KT LuxR family transcriptional regulator
IKDGHLII_01146 2e-195 T COG4585 Signal transduction histidine kinase
IKDGHLII_01147 4.7e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IKDGHLII_01148 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
IKDGHLII_01149 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
IKDGHLII_01150 6.9e-52 S LrgA family
IKDGHLII_01151 2.9e-93 yxaC M effector of murein hydrolase
IKDGHLII_01152 3.6e-162 dkgB S Aldo/keto reductase family
IKDGHLII_01153 1.2e-131 ybdO S Domain of unknown function (DUF4885)
IKDGHLII_01154 7.3e-100 ybdN
IKDGHLII_01155 3.7e-106 S ABC-2 family transporter protein
IKDGHLII_01156 5.4e-153 V ATPases associated with a variety of cellular activities
IKDGHLII_01157 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IKDGHLII_01158 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IKDGHLII_01159 1.3e-223 ybbR S protein conserved in bacteria
IKDGHLII_01160 1.8e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IKDGHLII_01161 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IKDGHLII_01162 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
IKDGHLII_01168 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
IKDGHLII_01169 7.7e-85 ybbJ J acetyltransferase
IKDGHLII_01170 1.1e-159 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IKDGHLII_01171 8.6e-238 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IKDGHLII_01172 5.8e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
IKDGHLII_01173 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
IKDGHLII_01174 2.4e-234 ybbC 3.2.1.52 S protein conserved in bacteria
IKDGHLII_01175 2.3e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
IKDGHLII_01176 2e-172 feuA P Iron-uptake system-binding protein
IKDGHLII_01177 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKDGHLII_01178 4e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKDGHLII_01179 6e-108 ybbA S Putative esterase
IKDGHLII_01180 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
IKDGHLII_01181 5.1e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
IKDGHLII_01182 4.4e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
IKDGHLII_01183 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
IKDGHLII_01184 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IKDGHLII_01185 9.4e-220 glcP G Major Facilitator Superfamily
IKDGHLII_01186 3.4e-39 S COG NOG14552 non supervised orthologous group
IKDGHLII_01189 1.6e-08
IKDGHLII_01192 3.4e-39 S COG NOG14552 non supervised orthologous group
IKDGHLII_01193 2.1e-132 pdaB 3.5.1.104 G Polysaccharide deacetylase
IKDGHLII_01194 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
IKDGHLII_01195 1.7e-75 gerD
IKDGHLII_01196 7.4e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IKDGHLII_01197 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IKDGHLII_01198 1.4e-77 ybaK S Protein of unknown function (DUF2521)
IKDGHLII_01199 1.2e-82 yizA S Damage-inducible protein DinB
IKDGHLII_01200 6.9e-144 ybaJ Q Methyltransferase domain
IKDGHLII_01201 6.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
IKDGHLII_01202 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IKDGHLII_01203 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IKDGHLII_01204 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKDGHLII_01205 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKDGHLII_01206 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IKDGHLII_01207 4.7e-58 rplQ J Ribosomal protein L17
IKDGHLII_01208 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKDGHLII_01209 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IKDGHLII_01210 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IKDGHLII_01211 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IKDGHLII_01212 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IKDGHLII_01213 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
IKDGHLII_01214 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IKDGHLII_01215 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IKDGHLII_01216 4.1e-72 rplO J binds to the 23S rRNA
IKDGHLII_01217 1.9e-23 rpmD J Ribosomal protein L30
IKDGHLII_01218 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IKDGHLII_01219 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IKDGHLII_01220 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IKDGHLII_01221 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IKDGHLII_01222 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IKDGHLII_01223 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IKDGHLII_01224 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IKDGHLII_01225 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IKDGHLII_01226 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IKDGHLII_01227 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IKDGHLII_01228 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IKDGHLII_01229 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IKDGHLII_01230 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IKDGHLII_01231 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IKDGHLII_01232 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IKDGHLII_01233 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IKDGHLII_01234 3e-105 rplD J Forms part of the polypeptide exit tunnel
IKDGHLII_01235 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IKDGHLII_01236 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IKDGHLII_01237 6.2e-182 ybaC 3.4.11.5 S Alpha/beta hydrolase family
IKDGHLII_01238 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IKDGHLII_01239 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IKDGHLII_01240 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IKDGHLII_01241 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IKDGHLII_01242 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
IKDGHLII_01243 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKDGHLII_01244 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IKDGHLII_01245 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
IKDGHLII_01246 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IKDGHLII_01247 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IKDGHLII_01248 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IKDGHLII_01249 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IKDGHLII_01250 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
IKDGHLII_01251 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IKDGHLII_01252 8.9e-116 sigH K Belongs to the sigma-70 factor family
IKDGHLII_01253 4.2e-89 yacP S RNA-binding protein containing a PIN domain
IKDGHLII_01254 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IKDGHLII_01255 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IKDGHLII_01256 5.3e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IKDGHLII_01257 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
IKDGHLII_01258 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IKDGHLII_01259 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IKDGHLII_01260 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IKDGHLII_01261 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
IKDGHLII_01262 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IKDGHLII_01263 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IKDGHLII_01264 0.0 clpC O Belongs to the ClpA ClpB family
IKDGHLII_01265 7.2e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IKDGHLII_01266 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
IKDGHLII_01267 1.3e-76 ctsR K Belongs to the CtsR family
IKDGHLII_01268 3.4e-39 S COG NOG14552 non supervised orthologous group
IKDGHLII_01273 2e-08
IKDGHLII_01276 1.3e-07
IKDGHLII_01278 3.4e-39 S COG NOG14552 non supervised orthologous group
IKDGHLII_01279 2.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IKDGHLII_01280 1.7e-187 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IKDGHLII_01281 4.5e-29 yazB K transcriptional
IKDGHLII_01282 2.4e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IKDGHLII_01283 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IKDGHLII_01284 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IKDGHLII_01285 2.5e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
IKDGHLII_01286 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
IKDGHLII_01287 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IKDGHLII_01288 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IKDGHLII_01289 3.8e-154 yacD 5.2.1.8 O peptidyl-prolyl isomerase
IKDGHLII_01290 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IKDGHLII_01291 3.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IKDGHLII_01292 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IKDGHLII_01293 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IKDGHLII_01294 2.1e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IKDGHLII_01295 1.4e-184 KLT serine threonine protein kinase
IKDGHLII_01296 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
IKDGHLII_01297 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
IKDGHLII_01300 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
IKDGHLII_01301 4.1e-57 divIC D Septum formation initiator
IKDGHLII_01302 2.9e-103 yabQ S spore cortex biosynthesis protein
IKDGHLII_01303 1.9e-49 yabP S Sporulation protein YabP
IKDGHLII_01304 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IKDGHLII_01305 1.8e-273 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IKDGHLII_01306 5e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKDGHLII_01307 6.2e-91 spoVT K stage V sporulation protein
IKDGHLII_01308 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IKDGHLII_01309 3.7e-40 yabK S Peptide ABC transporter permease
IKDGHLII_01310 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IKDGHLII_01311 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IKDGHLII_01312 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IKDGHLII_01313 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IKDGHLII_01314 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IKDGHLII_01315 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
IKDGHLII_01316 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IKDGHLII_01317 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IKDGHLII_01318 1.4e-26 sspF S DNA topological change
IKDGHLII_01319 7.8e-39 veg S protein conserved in bacteria
IKDGHLII_01320 8.4e-146 yabG S peptidase
IKDGHLII_01321 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IKDGHLII_01322 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IKDGHLII_01323 2.7e-231 rpfB GH23 T protein conserved in bacteria
IKDGHLII_01324 4.5e-143 tatD L hydrolase, TatD
IKDGHLII_01325 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IKDGHLII_01326 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
IKDGHLII_01327 4.2e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IKDGHLII_01328 5.2e-47 yazA L endonuclease containing a URI domain
IKDGHLII_01329 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
IKDGHLII_01330 7.7e-37 yabA L Involved in initiation control of chromosome replication
IKDGHLII_01331 8.8e-145 yaaT S stage 0 sporulation protein
IKDGHLII_01332 1.3e-182 holB 2.7.7.7 L DNA polymerase III
IKDGHLII_01333 1.2e-71 yaaR S protein conserved in bacteria
IKDGHLII_01334 7.5e-55 yaaQ S protein conserved in bacteria
IKDGHLII_01335 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IKDGHLII_01336 6.4e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
IKDGHLII_01337 1.1e-187 yaaN P Belongs to the TelA family
IKDGHLII_01338 5.6e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IKDGHLII_01339 3.8e-30 csfB S Inhibitor of sigma-G Gin
IKDGHLII_01342 3.4e-39 S COG NOG14552 non supervised orthologous group
IKDGHLII_01343 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
IKDGHLII_01344 3.6e-32 yaaL S Protein of unknown function (DUF2508)
IKDGHLII_01345 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IKDGHLII_01346 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IKDGHLII_01347 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IKDGHLII_01348 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IKDGHLII_01349 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
IKDGHLII_01350 4.4e-212 yaaH M Glycoside Hydrolase Family
IKDGHLII_01351 1e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
IKDGHLII_01352 4.5e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
IKDGHLII_01353 1.3e-09
IKDGHLII_01354 8.6e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IKDGHLII_01355 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IKDGHLII_01356 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IKDGHLII_01357 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IKDGHLII_01358 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IKDGHLII_01359 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IKDGHLII_01360 6.3e-182 yaaC S YaaC-like Protein
IKDGHLII_01363 3.4e-39 S COG NOG14552 non supervised orthologous group
IKDGHLII_01364 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IKDGHLII_01365 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IKDGHLII_01366 3.1e-37 yaaB S Domain of unknown function (DUF370)
IKDGHLII_01367 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IKDGHLII_01368 2.4e-33 yaaA S S4 domain
IKDGHLII_01369 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IKDGHLII_01370 1.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IKDGHLII_01371 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IKDGHLII_01372 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IKDGHLII_01373 1.3e-108 jag S single-stranded nucleic acid binding R3H
IKDGHLII_01374 1.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IKDGHLII_01375 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IKDGHLII_01376 1.6e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IKDGHLII_01377 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IKDGHLII_01378 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
IKDGHLII_01379 7.9e-149 spo0J K Belongs to the ParB family
IKDGHLII_01380 6.2e-111 yyaC S Sporulation protein YyaC
IKDGHLII_01381 4e-176 yyaD S Membrane
IKDGHLII_01382 2.3e-33 yyzM S protein conserved in bacteria
IKDGHLII_01383 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IKDGHLII_01384 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IKDGHLII_01385 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
IKDGHLII_01386 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IKDGHLII_01387 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IKDGHLII_01388 2.2e-105 adaA 3.2.2.21 K Transcriptional regulator
IKDGHLII_01389 1.8e-96 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IKDGHLII_01390 2.3e-139 xth 3.1.11.2 L exodeoxyribonuclease III
IKDGHLII_01391 1.8e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
IKDGHLII_01392 4.9e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKDGHLII_01393 2.6e-247 ydjK G Sugar (and other) transporter
IKDGHLII_01394 4.3e-161 yyaK S CAAX protease self-immunity
IKDGHLII_01395 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
IKDGHLII_01396 2.7e-40 qacC U Small Multidrug Resistance protein
IKDGHLII_01397 3.3e-78 K Transcriptional regulator
IKDGHLII_01398 1.1e-99 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IKDGHLII_01399 4e-130 ydfC EG EamA-like transporter family
IKDGHLII_01400 2.5e-251 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKDGHLII_01401 3.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IKDGHLII_01402 2.5e-161 K Transcriptional regulator
IKDGHLII_01403 5.2e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
IKDGHLII_01404 4.9e-162 eaeH M Domain of Unknown Function (DUF1259)
IKDGHLII_01405 1.6e-76 yybA 2.3.1.57 K transcriptional
IKDGHLII_01406 1.5e-150 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IKDGHLII_01407 4.1e-69 ydgJ K Winged helix DNA-binding domain
IKDGHLII_01408 5.6e-115 drgA C nitroreductase
IKDGHLII_01409 2.2e-55 ypaA S Protein of unknown function (DUF1304)
IKDGHLII_01410 1e-157 G Major Facilitator Superfamily
IKDGHLII_01411 1.8e-71 dinB S PFAM DinB family protein
IKDGHLII_01412 3.2e-113 K FCD domain
IKDGHLII_01413 2.1e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
IKDGHLII_01414 2.2e-273 sacB 2.4.1.10 GH68 M levansucrase activity
IKDGHLII_01415 9.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IKDGHLII_01416 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
IKDGHLII_01417 4e-65 ydeP3 K Transcriptional regulator
IKDGHLII_01418 2.1e-83 cotF M Spore coat protein
IKDGHLII_01420 1.2e-158 yybS S membrane
IKDGHLII_01421 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IKDGHLII_01422 4.9e-73 rplI J binds to the 23S rRNA
IKDGHLII_01423 6.4e-122 KLT COG0515 Serine threonine protein kinase
IKDGHLII_01424 1.1e-121 S GlcNAc-PI de-N-acetylase
IKDGHLII_01425 5.1e-243 M Glycosyltransferase Family 4
IKDGHLII_01426 2.1e-232 S Carbamoyl-phosphate synthase L chain, ATP binding domain
IKDGHLII_01427 6.9e-203 S Ecdysteroid kinase
IKDGHLII_01428 2.2e-235 M Glycosyltransferase Family 4
IKDGHLII_01429 4.6e-17 yycC K YycC-like protein
IKDGHLII_01431 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
IKDGHLII_01432 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IKDGHLII_01433 8.5e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKDGHLII_01434 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IKDGHLII_01439 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKDGHLII_01440 0.0 vicK 2.7.13.3 T Histidine kinase
IKDGHLII_01441 2.5e-261 yycH S protein conserved in bacteria
IKDGHLII_01442 1.1e-150 yycI S protein conserved in bacteria
IKDGHLII_01443 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IKDGHLII_01444 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IKDGHLII_01445 2.8e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKDGHLII_01446 4.3e-248 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
IKDGHLII_01447 1e-187 2.7.7.73, 2.7.7.80 H ThiF family
IKDGHLII_01448 6.1e-257
IKDGHLII_01449 4.5e-195 S Major Facilitator Superfamily
IKDGHLII_01450 1.3e-304 S ABC transporter
IKDGHLII_01451 5.9e-145 1.14.11.27 P peptidyl-arginine hydroxylation
IKDGHLII_01452 2.7e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IKDGHLII_01453 2.2e-42 sdpR K transcriptional
IKDGHLII_01454 4.2e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IKDGHLII_01455 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
IKDGHLII_01456 1.1e-256 rocE E amino acid
IKDGHLII_01457 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
IKDGHLII_01458 2.2e-199 S Histidine kinase
IKDGHLII_01460 1.4e-86 yycN 2.3.1.128 K Acetyltransferase
IKDGHLII_01461 2.5e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
IKDGHLII_01462 4.5e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IKDGHLII_01463 1.8e-215 yycP
IKDGHLII_01465 7.9e-08 S YyzF-like protein
IKDGHLII_01466 2.6e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IKDGHLII_01467 7.3e-184 S AIPR protein
IKDGHLII_01468 3.5e-192 D PHP domain protein
IKDGHLII_01469 8.2e-177 S Fusaric acid resistance protein-like
IKDGHLII_01470 4.1e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IKDGHLII_01471 4.3e-88 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
IKDGHLII_01472 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IKDGHLII_01473 2.6e-152 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IKDGHLII_01474 5.4e-83 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IKDGHLII_01475 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
IKDGHLII_01476 9.3e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
IKDGHLII_01477 1.1e-286 ahpF O Alkyl hydroperoxide reductase
IKDGHLII_01478 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
IKDGHLII_01479 1.6e-91 mrr V Mrr N-terminal domain
IKDGHLII_01480 1.3e-21 3.4.24.84 O metalloendopeptidase activity
IKDGHLII_01481 2.3e-249 L COG0210 Superfamily I DNA and RNA helicases
IKDGHLII_01482 1.9e-124 E Ring-cleavage extradiol dioxygenase
IKDGHLII_01483 3.8e-73 yxaI S membrane protein domain
IKDGHLII_01484 1.9e-201 EGP Major facilitator Superfamily
IKDGHLII_01485 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
IKDGHLII_01486 1.7e-64 S Family of unknown function (DUF5391)
IKDGHLII_01487 1.1e-141 S PQQ-like domain
IKDGHLII_01488 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IKDGHLII_01489 4.3e-214 yxbF K Bacterial regulatory proteins, tetR family
IKDGHLII_01490 1.8e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
IKDGHLII_01491 4.5e-200 desK 2.7.13.3 T Histidine kinase
IKDGHLII_01492 2.3e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKDGHLII_01493 1.8e-150 IQ Enoyl-(Acyl carrier protein) reductase
IKDGHLII_01495 0.0 htpG O Molecular chaperone. Has ATPase activity
IKDGHLII_01496 4.3e-245 csbC EGP Major facilitator Superfamily
IKDGHLII_01497 4.6e-174 iolS C Aldo keto reductase
IKDGHLII_01498 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
IKDGHLII_01499 2.1e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IKDGHLII_01500 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IKDGHLII_01501 2.7e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IKDGHLII_01502 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IKDGHLII_01503 3.4e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IKDGHLII_01504 5.1e-232 iolF EGP Major facilitator Superfamily
IKDGHLII_01505 2e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IKDGHLII_01506 3.3e-166 iolH G Xylose isomerase-like TIM barrel
IKDGHLII_01507 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IKDGHLII_01508 1.2e-155 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IKDGHLII_01509 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKDGHLII_01510 2.5e-175 T PhoQ Sensor
IKDGHLII_01511 1.4e-139 yxdL V ABC transporter, ATP-binding protein
IKDGHLII_01512 0.0 yxdM V ABC transporter (permease)
IKDGHLII_01513 1.3e-57 yxeA S Protein of unknown function (DUF1093)
IKDGHLII_01514 4.1e-178 fhuD P Periplasmic binding protein
IKDGHLII_01515 1e-34
IKDGHLII_01516 8.4e-23 yxeD
IKDGHLII_01520 2.6e-149 yidA S hydrolases of the HAD superfamily
IKDGHLII_01521 9.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IKDGHLII_01522 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IKDGHLII_01523 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IKDGHLII_01524 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
IKDGHLII_01525 4.4e-253 lysP E amino acid
IKDGHLII_01526 2.1e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IKDGHLII_01527 5.7e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
IKDGHLII_01528 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IKDGHLII_01529 3.6e-285 hutH 4.3.1.3 E Histidine ammonia-lyase
IKDGHLII_01530 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IKDGHLII_01531 5.3e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IKDGHLII_01532 3e-71 L NgoFVII restriction endonuclease
IKDGHLII_01533 8.5e-101 S GTP binding
IKDGHLII_01534 1.9e-182 2.1.1.37 H C-5 cytosine-specific DNA methylase
IKDGHLII_01535 5.1e-45 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
IKDGHLII_01536 1.1e-13 S Domain of unknown function (DUF5082)
IKDGHLII_01537 2.3e-31 L Replication protein
IKDGHLII_01538 1.5e-50 L Replication protein
IKDGHLII_01539 9e-25
IKDGHLII_01541 2.5e-64 K Transcriptional regulator
IKDGHLII_01544 1.8e-72 yxiE T Belongs to the universal stress protein A family
IKDGHLII_01545 3.6e-147 yxxF EG EamA-like transporter family
IKDGHLII_01546 1.2e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
IKDGHLII_01547 0.0 wapA M COG3209 Rhs family protein
IKDGHLII_01548 2.1e-117
IKDGHLII_01549 1.2e-84 S Protein of unknown function (DUF4240)
IKDGHLII_01551 2.1e-62 yxxG
IKDGHLII_01552 2.3e-69 yxiG
IKDGHLII_01556 2.8e-32
IKDGHLII_01557 1e-78
IKDGHLII_01559 1.1e-14 S YxiJ-like protein
IKDGHLII_01560 4.2e-22
IKDGHLII_01561 4.6e-48 yxiI S Protein of unknown function (DUF2716)
IKDGHLII_01562 2.7e-61 S SMI1-KNR4 cell-wall
IKDGHLII_01565 1.5e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IKDGHLII_01566 7.9e-222 yxiO S COG2270 Permeases of the major facilitator superfamily
IKDGHLII_01567 4.1e-21 licT K transcriptional antiterminator
IKDGHLII_01568 6.8e-44 licT K transcriptional antiterminator
IKDGHLII_01569 1.3e-40 licT K transcriptional antiterminator
IKDGHLII_01571 9.8e-140 exoK GH16 M licheninase activity
IKDGHLII_01572 3.1e-221 citH C Citrate transporter
IKDGHLII_01573 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
IKDGHLII_01574 4.3e-49 yxiS
IKDGHLII_01575 1.8e-71 T Domain of unknown function (DUF4163)
IKDGHLII_01576 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IKDGHLII_01577 1.9e-153 rlmA 2.1.1.187 Q Methyltransferase domain
IKDGHLII_01578 6.9e-217 yxjG 2.1.1.14 E Methionine synthase
IKDGHLII_01579 2e-85 yxjI S LURP-one-related
IKDGHLII_01582 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IKDGHLII_01583 8.2e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IKDGHLII_01584 3.8e-87 yxkC S Domain of unknown function (DUF4352)
IKDGHLII_01585 7.5e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IKDGHLII_01586 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
IKDGHLII_01587 2.6e-205 msmK P Belongs to the ABC transporter superfamily
IKDGHLII_01588 1.2e-154 yxkH G Polysaccharide deacetylase
IKDGHLII_01589 1e-214 cimH C COG3493 Na citrate symporter
IKDGHLII_01590 4.5e-266 cydA 1.10.3.14 C oxidase, subunit
IKDGHLII_01591 2.5e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
IKDGHLII_01592 0.0 cydD V ATP-binding
IKDGHLII_01593 6.5e-291 cydD V ATP-binding protein
IKDGHLII_01594 6.5e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IKDGHLII_01595 7.9e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
IKDGHLII_01596 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IKDGHLII_01597 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IKDGHLII_01598 2.1e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
IKDGHLII_01599 1.2e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
IKDGHLII_01600 1.1e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
IKDGHLII_01601 8.1e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IKDGHLII_01602 3.5e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IKDGHLII_01603 2.3e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
IKDGHLII_01604 5.8e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
IKDGHLII_01605 2.9e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IKDGHLII_01606 3.8e-57 arsR K transcriptional
IKDGHLII_01607 1.5e-166 cbrA3 P Periplasmic binding protein
IKDGHLII_01608 7.9e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKDGHLII_01609 2.8e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKDGHLII_01610 3.5e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IKDGHLII_01611 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
IKDGHLII_01612 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
IKDGHLII_01613 1.7e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IKDGHLII_01614 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
IKDGHLII_01615 4.6e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IKDGHLII_01616 1.9e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IKDGHLII_01617 3.1e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IKDGHLII_01618 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_01619 4.8e-229 dltB M membrane protein involved in D-alanine export
IKDGHLII_01620 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_01621 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
IKDGHLII_01622 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
IKDGHLII_01623 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
IKDGHLII_01624 1.3e-195 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IKDGHLII_01625 7.1e-49 ywaE K Transcriptional regulator
IKDGHLII_01626 4.1e-161 gspA M General stress
IKDGHLII_01627 5.4e-261 epr 3.4.21.62 O Belongs to the peptidase S8 family
IKDGHLII_01628 7.1e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IKDGHLII_01629 7.6e-67 ywbC 4.4.1.5 E glyoxalase
IKDGHLII_01630 8.8e-223 ywbD 2.1.1.191 J Methyltransferase
IKDGHLII_01631 4.8e-137 mta K transcriptional
IKDGHLII_01632 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
IKDGHLII_01633 1.3e-109 ywbG M effector of murein hydrolase
IKDGHLII_01634 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IKDGHLII_01635 8.2e-152 ywbI K Transcriptional regulator
IKDGHLII_01636 4.8e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IKDGHLII_01637 1.9e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IKDGHLII_01638 8.2e-25 ycdO P iron ion transport
IKDGHLII_01639 2e-241 ywbN P Dyp-type peroxidase family protein
IKDGHLII_01640 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IKDGHLII_01641 1.6e-131 S Streptomycin biosynthesis protein StrF
IKDGHLII_01642 4.3e-129 H Methionine biosynthesis protein MetW
IKDGHLII_01644 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
IKDGHLII_01645 5.1e-61 gtcA S GtrA-like protein
IKDGHLII_01646 3.3e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IKDGHLII_01647 8.4e-27 ywzA S membrane
IKDGHLII_01648 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IKDGHLII_01649 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IKDGHLII_01650 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IKDGHLII_01651 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IKDGHLII_01652 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
IKDGHLII_01653 1.7e-76 ysnE K acetyltransferase
IKDGHLII_01654 1.6e-208 rodA D Belongs to the SEDS family
IKDGHLII_01655 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
IKDGHLII_01656 1.1e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKDGHLII_01657 0.0 vpr O Belongs to the peptidase S8 family
IKDGHLII_01659 2.8e-151 sacT K transcriptional antiterminator
IKDGHLII_01660 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IKDGHLII_01661 4.1e-283 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
IKDGHLII_01662 7.4e-20 ywdA
IKDGHLII_01663 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IKDGHLII_01664 6.3e-57 pex K Transcriptional regulator PadR-like family
IKDGHLII_01665 1.3e-87 ywdD
IKDGHLII_01667 1.8e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
IKDGHLII_01668 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IKDGHLII_01669 4.7e-41 ywdI S Family of unknown function (DUF5327)
IKDGHLII_01670 5.4e-229 ywdJ F Xanthine uracil
IKDGHLII_01671 4.2e-46 ywdK S small membrane protein
IKDGHLII_01672 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IKDGHLII_01673 1.7e-142 spsA M Spore Coat
IKDGHLII_01674 9.1e-275 spsB M Capsule polysaccharide biosynthesis protein
IKDGHLII_01675 3.8e-218 spsC E Belongs to the DegT DnrJ EryC1 family
IKDGHLII_01676 2.6e-155 spsD 2.3.1.210 K Spore Coat
IKDGHLII_01677 2.4e-214 spsE 2.5.1.56 M acid synthase
IKDGHLII_01678 7.7e-132 spsF M Spore Coat
IKDGHLII_01679 1.1e-178 spsG M Spore Coat
IKDGHLII_01680 1.3e-136 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IKDGHLII_01681 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IKDGHLII_01682 4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IKDGHLII_01683 3e-86 spsL 5.1.3.13 M Spore Coat
IKDGHLII_01684 4.1e-59
IKDGHLII_01685 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IKDGHLII_01686 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IKDGHLII_01687 0.0 rocB E arginine degradation protein
IKDGHLII_01688 1.2e-258 lysP E amino acid
IKDGHLII_01689 9.3e-204 tcaB EGP Major facilitator Superfamily
IKDGHLII_01690 2.3e-221 ywfA EGP Major facilitator Superfamily
IKDGHLII_01691 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IKDGHLII_01692 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IKDGHLII_01693 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKDGHLII_01694 2.4e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IKDGHLII_01695 1e-207 bacE EGP Major facilitator Superfamily
IKDGHLII_01696 1.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
IKDGHLII_01697 5.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
IKDGHLII_01698 1.1e-146 ywfI C May function as heme-dependent peroxidase
IKDGHLII_01699 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
IKDGHLII_01700 5.3e-157 MA20_14895 S Conserved hypothetical protein 698
IKDGHLII_01701 6e-163 cysL K Transcriptional regulator
IKDGHLII_01702 1.8e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IKDGHLII_01703 2.1e-40 V ABC transporter, ATP-binding protein
IKDGHLII_01704 1.2e-92 S membrane
IKDGHLII_01705 9.7e-52 padR K PadR family transcriptional regulator
IKDGHLII_01706 6.6e-110 rsfA_1
IKDGHLII_01707 6.9e-36 ywzC S Belongs to the UPF0741 family
IKDGHLII_01708 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
IKDGHLII_01709 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
IKDGHLII_01710 1.9e-245 yhdG_1 E C-terminus of AA_permease
IKDGHLII_01711 4.9e-67 ywhA K Transcriptional regulator
IKDGHLII_01712 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
IKDGHLII_01713 1.2e-117 ywhC S Peptidase family M50
IKDGHLII_01714 2.9e-93 ywhD S YwhD family
IKDGHLII_01715 4.2e-82
IKDGHLII_01716 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IKDGHLII_01717 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IKDGHLII_01718 1.7e-167 speB 3.5.3.11 E Belongs to the arginase family
IKDGHLII_01721 1.3e-74 CP Membrane
IKDGHLII_01723 3.6e-31
IKDGHLII_01724 9.7e-29 ydcG K sequence-specific DNA binding
IKDGHLII_01726 6.4e-77 S aspartate phosphatase
IKDGHLII_01727 2.9e-43 ywiB S protein conserved in bacteria
IKDGHLII_01728 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IKDGHLII_01729 5.4e-212 narK P COG2223 Nitrate nitrite transporter
IKDGHLII_01730 1.9e-127 fnr K helix_turn_helix, cAMP Regulatory protein
IKDGHLII_01731 2.8e-139 ywiC S YwiC-like protein
IKDGHLII_01732 1e-84 arfM T cyclic nucleotide binding
IKDGHLII_01733 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IKDGHLII_01734 4.8e-295 narH 1.7.5.1 C Nitrate reductase, beta
IKDGHLII_01735 7.9e-89 narJ 1.7.5.1 C nitrate reductase
IKDGHLII_01736 6.1e-120 narI 1.7.5.1 C nitrate reductase, gamma
IKDGHLII_01737 7.5e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IKDGHLII_01738 1.6e-296 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IKDGHLII_01739 0.0 ywjA V ABC transporter
IKDGHLII_01740 4.2e-43 ywjC
IKDGHLII_01741 1.3e-179 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IKDGHLII_01742 6.6e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IKDGHLII_01743 0.0 fadF C COG0247 Fe-S oxidoreductase
IKDGHLII_01744 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IKDGHLII_01745 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IKDGHLII_01746 2.4e-92 ywjG S Domain of unknown function (DUF2529)
IKDGHLII_01747 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
IKDGHLII_01748 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
IKDGHLII_01749 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IKDGHLII_01750 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IKDGHLII_01751 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
IKDGHLII_01752 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IKDGHLII_01753 1.1e-32 rpmE J Binds the 23S rRNA
IKDGHLII_01754 3.9e-102 tdk 2.7.1.21 F thymidine kinase
IKDGHLII_01755 0.0 sfcA 1.1.1.38 C malic enzyme
IKDGHLII_01756 6.8e-157 ywkB S Membrane transport protein
IKDGHLII_01757 2.2e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IKDGHLII_01758 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKDGHLII_01759 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IKDGHLII_01760 4.8e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IKDGHLII_01762 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
IKDGHLII_01763 4.4e-118 spoIIR S stage II sporulation protein R
IKDGHLII_01764 3.9e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
IKDGHLII_01765 1.5e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IKDGHLII_01766 1.3e-83 mntP P Probably functions as a manganese efflux pump
IKDGHLII_01767 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IKDGHLII_01768 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
IKDGHLII_01769 5.9e-97 ywlG S Belongs to the UPF0340 family
IKDGHLII_01770 5.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IKDGHLII_01771 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IKDGHLII_01772 2.1e-61 atpI S ATP synthase
IKDGHLII_01773 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
IKDGHLII_01774 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IKDGHLII_01775 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IKDGHLII_01776 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IKDGHLII_01777 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IKDGHLII_01778 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IKDGHLII_01779 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IKDGHLII_01780 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IKDGHLII_01781 8.7e-89 ywmA
IKDGHLII_01782 4.8e-32 ywzB S membrane
IKDGHLII_01783 2.2e-134 ywmB S TATA-box binding
IKDGHLII_01784 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IKDGHLII_01785 4e-179 spoIID D Stage II sporulation protein D
IKDGHLII_01786 5.1e-114 ywmC S protein containing a von Willebrand factor type A (vWA) domain
IKDGHLII_01787 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
IKDGHLII_01789 4.2e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IKDGHLII_01790 4.1e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IKDGHLII_01791 2.8e-93 S response regulator aspartate phosphatase
IKDGHLII_01792 2.3e-81 ywmF S Peptidase M50
IKDGHLII_01793 1.4e-10 csbD K CsbD-like
IKDGHLII_01794 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IKDGHLII_01795 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IKDGHLII_01796 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IKDGHLII_01797 6.1e-67 ywnA K Transcriptional regulator
IKDGHLII_01798 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
IKDGHLII_01799 4.5e-51 ywnC S Family of unknown function (DUF5362)
IKDGHLII_01800 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IKDGHLII_01801 4.2e-69 ywnF S Family of unknown function (DUF5392)
IKDGHLII_01802 1.2e-10 ywnC S Family of unknown function (DUF5362)
IKDGHLII_01803 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
IKDGHLII_01804 1.3e-119 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
IKDGHLII_01805 2.1e-70 ywnJ S VanZ like family
IKDGHLII_01806 4.6e-100 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
IKDGHLII_01807 3.9e-207 ftsW D Belongs to the SEDS family
IKDGHLII_01808 2e-58 nrgB K Belongs to the P(II) protein family
IKDGHLII_01809 2.5e-228 amt P Ammonium transporter
IKDGHLII_01810 4.8e-102 phzA Q Isochorismatase family
IKDGHLII_01811 1e-243 ywoD EGP Major facilitator superfamily
IKDGHLII_01812 1.3e-273 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
IKDGHLII_01813 1.9e-212 ywoG EGP Major facilitator Superfamily
IKDGHLII_01814 2.5e-71 ywoH K transcriptional
IKDGHLII_01815 1.8e-44 spoIIID K Stage III sporulation protein D
IKDGHLII_01816 2.7e-180 mbl D Rod shape-determining protein
IKDGHLII_01817 5.5e-128 flhO N flagellar basal body
IKDGHLII_01818 1.8e-142 flhP N flagellar basal body
IKDGHLII_01819 1.5e-197 S aspartate phosphatase
IKDGHLII_01820 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IKDGHLII_01821 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IKDGHLII_01822 2.5e-68 ywpF S YwpF-like protein
IKDGHLII_01823 4e-62 ywpG
IKDGHLII_01824 3.7e-57 ssbB L Single-stranded DNA-binding protein
IKDGHLII_01825 7.5e-138 glcR K DeoR C terminal sensor domain
IKDGHLII_01826 1.7e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
IKDGHLII_01827 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IKDGHLII_01828 6e-307 ywqB S SWIM zinc finger
IKDGHLII_01829 1.3e-14
IKDGHLII_01830 8.3e-110 ywqC M biosynthesis protein
IKDGHLII_01831 9.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
IKDGHLII_01832 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
IKDGHLII_01833 8.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IKDGHLII_01834 2.6e-146 ywqG S Domain of unknown function (DUF1963)
IKDGHLII_01836 1.4e-21 S Domain of unknown function (DUF5082)
IKDGHLII_01837 7.3e-37 ywqI S Family of unknown function (DUF5344)
IKDGHLII_01838 2.2e-302 ywqJ S Pre-toxin TG
IKDGHLII_01839 2.6e-49
IKDGHLII_01840 3.1e-41 S Protein of unknown function (DUF2004)
IKDGHLII_01841 1.7e-124 ywqJ S Pre-toxin TG
IKDGHLII_01843 4.5e-155 K Transcriptional regulator
IKDGHLII_01844 8.8e-93 ywqN S NAD(P)H-dependent
IKDGHLII_01846 3.2e-87 ywrA P COG2059 Chromate transport protein ChrA
IKDGHLII_01847 9.5e-101 ywrB P Chromate transporter
IKDGHLII_01848 2.5e-83 ywrC K Transcriptional regulator
IKDGHLII_01849 1.6e-299 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IKDGHLII_01851 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IKDGHLII_01852 2.2e-09
IKDGHLII_01853 5.5e-211 cotH M Spore Coat
IKDGHLII_01854 2.8e-128 cotB
IKDGHLII_01855 7.5e-126 ywrJ
IKDGHLII_01856 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IKDGHLII_01858 2.6e-166 alsR K LysR substrate binding domain
IKDGHLII_01859 2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IKDGHLII_01860 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
IKDGHLII_01861 5.3e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
IKDGHLII_01862 9.8e-89 batE T Sh3 type 3 domain protein
IKDGHLII_01863 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
IKDGHLII_01864 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
IKDGHLII_01865 7.1e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IKDGHLII_01866 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IKDGHLII_01867 4.8e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IKDGHLII_01868 1.1e-178 rbsR K transcriptional
IKDGHLII_01869 7.4e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
IKDGHLII_01870 8.2e-191 gerKB E Spore germination protein
IKDGHLII_01871 4.5e-184 gerKA EG Spore germination protein
IKDGHLII_01872 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
IKDGHLII_01873 2.3e-70 pgsC S biosynthesis protein
IKDGHLII_01874 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IKDGHLII_01875 1.3e-20 ywtC
IKDGHLII_01876 9.5e-236 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IKDGHLII_01877 5e-35 yttA 2.7.13.3 S Pfam Transposase IS66
IKDGHLII_01878 1.8e-156 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
IKDGHLII_01879 7.2e-178 ywtF K Transcriptional regulator
IKDGHLII_01880 4.9e-249 ywtG EGP Major facilitator Superfamily
IKDGHLII_01881 1.5e-266 GT2,GT4 J Glycosyl transferase family 2
IKDGHLII_01882 6.3e-210 gerAC S Spore germination protein
IKDGHLII_01883 7.8e-197 gerBB E Spore germination protein
IKDGHLII_01884 3.7e-263 gerBA EG Spore germination protein
IKDGHLII_01885 8.5e-184 pmi 5.3.1.8 G mannose-6-phosphate isomerase
IKDGHLII_01886 2.3e-239 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IKDGHLII_01887 5.5e-217 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IKDGHLII_01888 3.8e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IKDGHLII_01889 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
IKDGHLII_01890 7.8e-280 M Glycosyltransferase like family 2
IKDGHLII_01891 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IKDGHLII_01892 1.7e-151 tagG GM Transport permease protein
IKDGHLII_01893 1.1e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IKDGHLII_01894 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IKDGHLII_01895 1.3e-207 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IKDGHLII_01896 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IKDGHLII_01897 2.3e-48
IKDGHLII_01898 0.0 lytB 3.5.1.28 D Stage II sporulation protein
IKDGHLII_01899 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IKDGHLII_01900 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IKDGHLII_01901 3.5e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKDGHLII_01902 2.3e-223 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
IKDGHLII_01903 2e-247 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IKDGHLII_01904 3e-254 tuaE M Teichuronic acid biosynthesis protein
IKDGHLII_01905 6.6e-114 tuaF M protein involved in exopolysaccharide biosynthesis
IKDGHLII_01906 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
IKDGHLII_01907 3.9e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
IKDGHLII_01908 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IKDGHLII_01909 1e-165 yvhJ K Transcriptional regulator
IKDGHLII_01910 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
IKDGHLII_01911 3.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IKDGHLII_01912 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKDGHLII_01913 3.2e-158 degV S protein conserved in bacteria
IKDGHLII_01914 1.2e-255 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IKDGHLII_01915 1.7e-42 comFB S Late competence development protein ComFB
IKDGHLII_01916 2.9e-76 comFC S Phosphoribosyl transferase domain
IKDGHLII_01917 4.1e-74 yvyF S flagellar protein
IKDGHLII_01918 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
IKDGHLII_01919 8.9e-81 flgN NOU FlgN protein
IKDGHLII_01920 1.4e-273 flgK N flagellar hook-associated protein
IKDGHLII_01921 2.6e-161 flgL N Belongs to the bacterial flagellin family
IKDGHLII_01922 8.9e-80 yviE
IKDGHLII_01923 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IKDGHLII_01924 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IKDGHLII_01925 2e-103 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IKDGHLII_01926 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IKDGHLII_01927 3e-66 fliS N flagellar protein FliS
IKDGHLII_01928 4.5e-10 fliT S bacterial-type flagellum organization
IKDGHLII_01929 6.8e-68
IKDGHLII_01930 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IKDGHLII_01931 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IKDGHLII_01932 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IKDGHLII_01933 3e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
IKDGHLII_01934 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
IKDGHLII_01935 2.3e-122 ftsE D cell division ATP-binding protein FtsE
IKDGHLII_01936 4.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IKDGHLII_01937 1e-225 ywoF P Right handed beta helix region
IKDGHLII_01938 1.1e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
IKDGHLII_01939 1.5e-55 swrA S Swarming motility protein
IKDGHLII_01940 2.2e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IKDGHLII_01941 1.3e-177 S Psort location CytoplasmicMembrane, score
IKDGHLII_01942 5.6e-226 yvkA EGP Major facilitator Superfamily
IKDGHLII_01943 1.6e-109 yvkB K Transcriptional regulator
IKDGHLII_01944 0.0 yvkC 2.7.9.2 GT Phosphotransferase
IKDGHLII_01945 7.6e-33 csbA S protein conserved in bacteria
IKDGHLII_01946 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IKDGHLII_01947 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IKDGHLII_01948 2.2e-32 yvkN
IKDGHLII_01949 6.1e-49 yvlA
IKDGHLII_01950 1.2e-165 yvlB S Putative adhesin
IKDGHLII_01951 9.6e-26 pspB KT PspC domain
IKDGHLII_01952 1.5e-40 yvlD S Membrane
IKDGHLII_01953 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
IKDGHLII_01954 4.4e-103 yxaF K Transcriptional regulator
IKDGHLII_01955 2.3e-133 yvoA K transcriptional
IKDGHLII_01956 5.2e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IKDGHLII_01957 6.4e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IKDGHLII_01958 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IKDGHLII_01959 3.1e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IKDGHLII_01960 9.1e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IKDGHLII_01961 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
IKDGHLII_01962 3.5e-137 yvpB NU protein conserved in bacteria
IKDGHLII_01963 1e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IKDGHLII_01964 5.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IKDGHLII_01965 1.4e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IKDGHLII_01966 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IKDGHLII_01967 1.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IKDGHLII_01968 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IKDGHLII_01969 1.7e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IKDGHLII_01970 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
IKDGHLII_01971 0.0 msbA2 3.6.3.44 V ABC transporter
IKDGHLII_01972 2e-53
IKDGHLII_01973 1.2e-120 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKDGHLII_01974 1.2e-189 sasA T Histidine kinase
IKDGHLII_01975 5e-276 S COG0457 FOG TPR repeat
IKDGHLII_01976 1.3e-124 usp CBM50 M protein conserved in bacteria
IKDGHLII_01977 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IKDGHLII_01978 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IKDGHLII_01979 1.1e-166 rapZ S Displays ATPase and GTPase activities
IKDGHLII_01980 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IKDGHLII_01981 5.3e-170 whiA K May be required for sporulation
IKDGHLII_01982 4.7e-36 crh G Phosphocarrier protein Chr
IKDGHLII_01983 5.7e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
IKDGHLII_01984 8.2e-79 M Ribonuclease
IKDGHLII_01985 1.6e-182 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IKDGHLII_01986 1.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IKDGHLII_01987 1.6e-280 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
IKDGHLII_01988 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
IKDGHLII_01989 8.1e-105 yvdD 3.2.2.10 S Belongs to the LOG family
IKDGHLII_01990 2.6e-10 yvdD 3.2.2.10 S Belongs to the LOG family
IKDGHLII_01991 9.2e-248 EGP Sugar (and other) transporter
IKDGHLII_01992 1.4e-209 yraM S PrpF protein
IKDGHLII_01993 6.7e-164 yraN K Transcriptional regulator
IKDGHLII_01994 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IKDGHLII_01995 1.6e-182 scrR K transcriptional
IKDGHLII_01996 2.3e-218 rafB P LacY proton/sugar symporter
IKDGHLII_01997 1.3e-292 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
IKDGHLII_01999 2.6e-33
IKDGHLII_02000 1.1e-240 I Pfam Lipase (class 3)
IKDGHLII_02001 2.3e-15 S Protein of unknown function (DUF1433)
IKDGHLII_02002 2.2e-38 S Protein of unknown function (DUF1433)
IKDGHLII_02003 1.6e-93 padC Q Phenolic acid decarboxylase
IKDGHLII_02004 2.3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKDGHLII_02005 3.4e-112 yyaS S Membrane
IKDGHLII_02006 3.7e-96 ywjB H RibD C-terminal domain
IKDGHLII_02007 1.9e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
IKDGHLII_02008 1.9e-77 slr K transcriptional
IKDGHLII_02009 1.6e-118 ywqC M biosynthesis protein
IKDGHLII_02010 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
IKDGHLII_02011 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
IKDGHLII_02012 3.3e-219 epsD GT4 M Glycosyl transferase 4-like
IKDGHLII_02013 7.6e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IKDGHLII_02014 8.8e-212 epsF GT4 M Glycosyl transferases group 1
IKDGHLII_02015 7.7e-205 epsG S EpsG family
IKDGHLII_02016 1.9e-192 epsH GT2 S Glycosyltransferase like family 2
IKDGHLII_02017 1.4e-203 epsI GM pyruvyl transferase
IKDGHLII_02018 4.4e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
IKDGHLII_02019 5.3e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKDGHLII_02020 7e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IKDGHLII_02021 4.2e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
IKDGHLII_02022 7.7e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IKDGHLII_02023 7e-186 yvfF GM Exopolysaccharide biosynthesis protein
IKDGHLII_02024 2.7e-32 yvfG S YvfG protein
IKDGHLII_02025 1.4e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IKDGHLII_02026 3.8e-304 yvfH C L-lactate permease
IKDGHLII_02027 6.6e-120 yvfI K COG2186 Transcriptional regulators
IKDGHLII_02028 7.8e-219 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IKDGHLII_02029 3.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IKDGHLII_02030 4e-270 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IKDGHLII_02031 7.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IKDGHLII_02032 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
IKDGHLII_02033 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
IKDGHLII_02034 5e-151 ybbH_1 K RpiR family transcriptional regulator
IKDGHLII_02036 1.1e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
IKDGHLII_02037 1.7e-157 yvbV EG EamA-like transporter family
IKDGHLII_02038 2.4e-156 yvbU K Transcriptional regulator
IKDGHLII_02040 1.6e-188 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKDGHLII_02041 1.4e-203 araR K transcriptional
IKDGHLII_02042 7.4e-253 araE EGP Major facilitator Superfamily
IKDGHLII_02044 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IKDGHLII_02045 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IKDGHLII_02046 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IKDGHLII_02047 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IKDGHLII_02048 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
IKDGHLII_02049 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IKDGHLII_02050 5.8e-236 ywaD 3.4.11.10, 3.4.11.6 S PA domain
IKDGHLII_02051 8.9e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IKDGHLII_02052 1.7e-215 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IKDGHLII_02053 1.8e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
IKDGHLII_02054 2.2e-224 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IKDGHLII_02055 1e-146 M Protein involved in cellulose biosynthesis
IKDGHLII_02056 2.1e-142 C WbqC-like protein family
IKDGHLII_02057 7e-124 S GlcNAc-PI de-N-acetylase
IKDGHLII_02058 1.3e-176
IKDGHLII_02059 6.2e-211 EGP Major facilitator Superfamily
IKDGHLII_02060 1.5e-80 yvbK 3.1.3.25 K acetyltransferase
IKDGHLII_02061 0.0 tcaA S response to antibiotic
IKDGHLII_02062 6.4e-120 exoY M Membrane
IKDGHLII_02063 9.8e-104 yvbG U UPF0056 membrane protein
IKDGHLII_02064 3.5e-97 yvbF K Belongs to the GbsR family
IKDGHLII_02065 5.7e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IKDGHLII_02066 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IKDGHLII_02067 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IKDGHLII_02068 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IKDGHLII_02069 4.3e-76 yvbF K Belongs to the GbsR family
IKDGHLII_02070 2.5e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IKDGHLII_02071 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IKDGHLII_02072 3.3e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IKDGHLII_02073 5.2e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IKDGHLII_02074 1.2e-126 mutF V ABC transporter, ATP-binding protein
IKDGHLII_02075 1.7e-123 spaE S ABC-2 family transporter protein
IKDGHLII_02076 9.1e-136 mutG S ABC-2 family transporter protein
IKDGHLII_02077 1.4e-121 K Transcriptional regulatory protein, C terminal
IKDGHLII_02078 6.9e-259 T His Kinase A (phosphoacceptor) domain
IKDGHLII_02079 8.8e-53 yodB K transcriptional
IKDGHLII_02080 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
IKDGHLII_02081 1e-69 K transcriptional
IKDGHLII_02082 6e-35 yvzC K Transcriptional
IKDGHLII_02083 4.8e-24 secG U Preprotein translocase subunit SecG
IKDGHLII_02084 1.6e-142 est 3.1.1.1 S Carboxylesterase
IKDGHLII_02085 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IKDGHLII_02086 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IKDGHLII_02088 3.7e-48 yrdF K ribonuclease inhibitor
IKDGHLII_02089 6.9e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IKDGHLII_02090 2.5e-161 ytlI K LysR substrate binding domain
IKDGHLII_02091 3e-101 ytmI K Acetyltransferase (GNAT) domain
IKDGHLII_02092 3.9e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
IKDGHLII_02093 3e-145 tcyK M Bacterial periplasmic substrate-binding proteins
IKDGHLII_02094 1.7e-120 tcyL P Binding-protein-dependent transport system inner membrane component
IKDGHLII_02095 1.1e-119 tcyM U Binding-protein-dependent transport system inner membrane component
IKDGHLII_02096 3.6e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IKDGHLII_02097 2.4e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKDGHLII_02098 2.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
IKDGHLII_02099 3.2e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKDGHLII_02100 3.9e-142 S Amidohydrolase
IKDGHLII_02101 2.4e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
IKDGHLII_02102 2.2e-216 ynfM EGP Major Facilitator Superfamily
IKDGHLII_02103 8.4e-159 K Helix-turn-helix XRE-family like proteins
IKDGHLII_02104 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IKDGHLII_02105 1.1e-192 yvaA 1.1.1.371 S Oxidoreductase
IKDGHLII_02106 3.7e-48 csoR S transcriptional
IKDGHLII_02107 2.6e-29 copZ P Heavy-metal-associated domain
IKDGHLII_02108 0.0 copA 3.6.3.54 P P-type ATPase
IKDGHLII_02109 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IKDGHLII_02110 7.5e-102 bdbD O Thioredoxin
IKDGHLII_02111 6e-73 bdbC O Required for disulfide bond formation in some proteins
IKDGHLII_02112 1.1e-139 S Metallo-peptidase family M12
IKDGHLII_02113 2.3e-105 yvgT S membrane
IKDGHLII_02114 0.0 helD 3.6.4.12 L DNA helicase
IKDGHLII_02115 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IKDGHLII_02116 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IKDGHLII_02117 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
IKDGHLII_02118 2.7e-85 yvgO
IKDGHLII_02119 1.1e-155 yvgN S reductase
IKDGHLII_02120 7e-193 yfiN V COG0842 ABC-type multidrug transport system, permease component
IKDGHLII_02121 1.3e-191 yfiM V ABC-2 type transporter
IKDGHLII_02122 2.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
IKDGHLII_02123 2.1e-178 T Histidine kinase
IKDGHLII_02124 8.6e-114 yfiK K Regulator
IKDGHLII_02125 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
IKDGHLII_02126 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
IKDGHLII_02127 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
IKDGHLII_02128 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IKDGHLII_02129 5.1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
IKDGHLII_02130 5.2e-13 S Small spore protein J (Spore_SspJ)
IKDGHLII_02131 7e-235 yvsH E Arginine ornithine antiporter
IKDGHLII_02132 8.3e-128 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IKDGHLII_02133 4e-178 fhuD P ABC transporter
IKDGHLII_02134 1.1e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKDGHLII_02135 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKDGHLII_02136 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
IKDGHLII_02137 2.7e-65 yvrL S Regulatory protein YrvL
IKDGHLII_02138 7.8e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
IKDGHLII_02139 1.6e-15 S YvrJ protein family
IKDGHLII_02140 3.8e-102 yvrI K RNA polymerase
IKDGHLII_02141 1.1e-36
IKDGHLII_02142 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKDGHLII_02143 0.0 T PhoQ Sensor
IKDGHLII_02144 1.1e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
IKDGHLII_02145 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IKDGHLII_02146 7.9e-166 yvrC P ABC transporter substrate-binding protein
IKDGHLII_02147 3.4e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IKDGHLII_02148 6.8e-218 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IKDGHLII_02149 7e-101 yvqK 2.5.1.17 S Adenosyltransferase
IKDGHLII_02150 2.2e-227 yvqJ EGP Major facilitator Superfamily
IKDGHLII_02151 9e-44 liaI S membrane
IKDGHLII_02152 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IKDGHLII_02153 3.3e-126 liaG S Putative adhesin
IKDGHLII_02154 1.9e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
IKDGHLII_02155 2.3e-193 vraS 2.7.13.3 T Histidine kinase
IKDGHLII_02156 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKDGHLII_02157 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
IKDGHLII_02158 3.6e-186 gerAB E Spore germination protein
IKDGHLII_02159 1e-257 gerAA EG Spore germination protein
IKDGHLII_02160 6.6e-24 S Protein of unknown function (DUF3970)
IKDGHLII_02161 8.7e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IKDGHLII_02162 2.9e-157 yuxN K Transcriptional regulator
IKDGHLII_02163 3.4e-24
IKDGHLII_02164 2.5e-250 cssS 2.7.13.3 T PhoQ Sensor
IKDGHLII_02165 2.8e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKDGHLII_02166 3.8e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IKDGHLII_02167 4.7e-79 dps P Belongs to the Dps family
IKDGHLII_02168 3.9e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IKDGHLII_02169 0.0 pepF2 E COG1164 Oligoendopeptidase F
IKDGHLII_02170 7.2e-45 S YusW-like protein
IKDGHLII_02171 3.1e-150 yusV 3.6.3.34 HP ABC transporter
IKDGHLII_02172 3.3e-39 yusU S Protein of unknown function (DUF2573)
IKDGHLII_02173 4.9e-185 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IKDGHLII_02174 4.2e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
IKDGHLII_02175 1.1e-153 ywbI2 K Transcriptional regulator
IKDGHLII_02176 4e-287 yusP P Major facilitator superfamily
IKDGHLII_02177 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
IKDGHLII_02178 1.1e-53 yusN M Coat F domain
IKDGHLII_02179 6.7e-43
IKDGHLII_02180 1.4e-164 fadM E Proline dehydrogenase
IKDGHLII_02181 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
IKDGHLII_02182 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
IKDGHLII_02183 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
IKDGHLII_02184 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
IKDGHLII_02185 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IKDGHLII_02186 3.7e-40 yusG S Protein of unknown function (DUF2553)
IKDGHLII_02187 5.4e-62 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
IKDGHLII_02188 1.6e-54 yusE CO Thioredoxin
IKDGHLII_02189 1.5e-56 yusD S SCP-2 sterol transfer family
IKDGHLII_02190 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IKDGHLII_02191 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
IKDGHLII_02192 3e-145 metQ P Belongs to the NlpA lipoprotein family
IKDGHLII_02193 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IKDGHLII_02194 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IKDGHLII_02195 1.2e-244 sufD O assembly protein SufD
IKDGHLII_02196 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IKDGHLII_02197 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
IKDGHLII_02198 8.7e-270 sufB O FeS cluster assembly
IKDGHLII_02199 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IKDGHLII_02200 2.2e-24 yncE S Protein of unknown function (DUF2691)
IKDGHLII_02201 2e-200 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
IKDGHLII_02202 7e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
IKDGHLII_02204 2.1e-163 K helix_turn_helix, mercury resistance
IKDGHLII_02205 1e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IKDGHLII_02206 1.4e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
IKDGHLII_02207 9.8e-158 yurN G Binding-protein-dependent transport system inner membrane component
IKDGHLII_02208 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
IKDGHLII_02209 7.7e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
IKDGHLII_02210 3.6e-134 yurK K UTRA
IKDGHLII_02211 5.4e-206 msmX P Belongs to the ABC transporter superfamily
IKDGHLII_02212 1.9e-166 bsn L Ribonuclease
IKDGHLII_02213 1.8e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IKDGHLII_02214 1.8e-234 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IKDGHLII_02215 9.2e-212 blt EGP Major facilitator Superfamily
IKDGHLII_02218 6.4e-301 pucR QT COG2508 Regulator of polyketide synthase expression
IKDGHLII_02219 2.9e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IKDGHLII_02220 3.5e-58 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
IKDGHLII_02221 1.5e-168 yunF S Protein of unknown function DUF72
IKDGHLII_02222 4.3e-144 yunE S membrane transporter protein
IKDGHLII_02223 1.9e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IKDGHLII_02224 3.3e-130 yunB S Sporulation protein YunB (Spo_YunB)
IKDGHLII_02225 1.9e-191 lytH M Peptidase, M23
IKDGHLII_02226 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IKDGHLII_02227 1.7e-47 yutD S protein conserved in bacteria
IKDGHLII_02228 6.8e-72 yutE S Protein of unknown function DUF86
IKDGHLII_02229 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IKDGHLII_02230 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
IKDGHLII_02231 3e-195 yutH S Spore coat protein
IKDGHLII_02232 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
IKDGHLII_02233 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IKDGHLII_02234 9.8e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IKDGHLII_02235 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
IKDGHLII_02236 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
IKDGHLII_02237 2.8e-54 yuzD S protein conserved in bacteria
IKDGHLII_02238 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
IKDGHLII_02239 2.4e-39 yuzB S Belongs to the UPF0349 family
IKDGHLII_02240 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IKDGHLII_02241 1.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IKDGHLII_02242 1.1e-62 erpA S Belongs to the HesB IscA family
IKDGHLII_02243 1.2e-135 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
IKDGHLII_02244 2.3e-26 K helix_turn_helix, mercury resistance
IKDGHLII_02246 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
IKDGHLII_02248 1.5e-121 V ABC transporter
IKDGHLII_02249 1e-69 CP Membrane
IKDGHLII_02250 4.8e-29
IKDGHLII_02251 1.1e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IKDGHLII_02253 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
IKDGHLII_02254 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
IKDGHLII_02255 9.9e-28 yuiB S Putative membrane protein
IKDGHLII_02256 2.7e-117 yuiC S protein conserved in bacteria
IKDGHLII_02257 1.6e-77 yuiD S protein conserved in bacteria
IKDGHLII_02258 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IKDGHLII_02259 1.2e-207 yuiF S antiporter
IKDGHLII_02260 7.3e-101 bioY S Biotin biosynthesis protein
IKDGHLII_02261 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
IKDGHLII_02262 5.2e-164 besA S Putative esterase
IKDGHLII_02263 8.1e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IKDGHLII_02264 4.3e-217 entC 5.4.4.2 HQ Isochorismate synthase
IKDGHLII_02265 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
IKDGHLII_02266 3.6e-171 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
IKDGHLII_02267 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_02268 1.1e-33 mbtH S MbtH-like protein
IKDGHLII_02269 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
IKDGHLII_02270 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
IKDGHLII_02271 4.2e-228 yukF QT Transcriptional regulator
IKDGHLII_02272 3.3e-46 esxA S Belongs to the WXG100 family
IKDGHLII_02273 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
IKDGHLII_02274 1.2e-204 essB S WXG100 protein secretion system (Wss), protein YukC
IKDGHLII_02275 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IKDGHLII_02276 0.0 esaA S type VII secretion protein EsaA
IKDGHLII_02277 1.3e-76 yueC S Family of unknown function (DUF5383)
IKDGHLII_02278 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKDGHLII_02279 8.3e-96 yueE S phosphohydrolase
IKDGHLII_02280 1.6e-22 S Protein of unknown function (DUF2642)
IKDGHLII_02281 3.6e-186 yueF S transporter activity
IKDGHLII_02282 6.4e-34 yueG S Spore germination protein gerPA/gerPF
IKDGHLII_02283 2.8e-38 yueH S YueH-like protein
IKDGHLII_02284 7.2e-68 yueI S Protein of unknown function (DUF1694)
IKDGHLII_02285 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
IKDGHLII_02286 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IKDGHLII_02287 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
IKDGHLII_02288 1.2e-50 yuzC
IKDGHLII_02291 4.4e-62 comQ H Polyprenyl synthetase
IKDGHLII_02293 5.6e-176 comP 2.7.13.3 T Histidine kinase
IKDGHLII_02294 1.8e-84 comP 2.7.13.3 T Histidine kinase
IKDGHLII_02295 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IKDGHLII_02296 4.3e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
IKDGHLII_02297 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
IKDGHLII_02298 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IKDGHLII_02299 8.5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IKDGHLII_02300 1.7e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IKDGHLII_02301 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IKDGHLII_02302 1.3e-67 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IKDGHLII_02303 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IKDGHLII_02304 2.3e-12
IKDGHLII_02305 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
IKDGHLII_02306 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
IKDGHLII_02307 1.6e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IKDGHLII_02308 1.7e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IKDGHLII_02309 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
IKDGHLII_02310 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IKDGHLII_02311 9.3e-74 yufK S Family of unknown function (DUF5366)
IKDGHLII_02312 2.2e-72 yuxK S protein conserved in bacteria
IKDGHLII_02313 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
IKDGHLII_02314 1.5e-185 yuxJ EGP Major facilitator Superfamily
IKDGHLII_02315 4e-118 kapD L the KinA pathway to sporulation
IKDGHLII_02316 7.7e-67 kapB G Kinase associated protein B
IKDGHLII_02317 8.9e-229 T PhoQ Sensor
IKDGHLII_02318 3.3e-222 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IKDGHLII_02319 1.9e-40 yugE S Domain of unknown function (DUF1871)
IKDGHLII_02320 5.5e-155 yugF I Hydrolase
IKDGHLII_02321 2e-83 alaR K Transcriptional regulator
IKDGHLII_02322 1.6e-208 yugH 2.6.1.1 E Aminotransferase
IKDGHLII_02323 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
IKDGHLII_02324 1.8e-34 yuzA S Domain of unknown function (DUF378)
IKDGHLII_02325 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
IKDGHLII_02326 1.8e-228 yugK C Dehydrogenase
IKDGHLII_02327 5.5e-118 ycaC Q Isochorismatase family
IKDGHLII_02328 2.5e-17 S NADPH-dependent FMN reductase
IKDGHLII_02329 1.6e-45 S NADPH-dependent FMN reductase
IKDGHLII_02330 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
IKDGHLII_02332 7e-71 yugN S YugN-like family
IKDGHLII_02333 1.2e-180 yugO P COG1226 Kef-type K transport systems
IKDGHLII_02334 6.7e-27 mstX S Membrane-integrating protein Mistic
IKDGHLII_02335 3.4e-18
IKDGHLII_02336 8.3e-117 yugP S Zn-dependent protease
IKDGHLII_02337 6.6e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
IKDGHLII_02338 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
IKDGHLII_02339 2e-73 yugU S Uncharacterised protein family UPF0047
IKDGHLII_02340 3.3e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IKDGHLII_02341 1.4e-40
IKDGHLII_02342 2.2e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
IKDGHLII_02343 8.1e-221 mcpA NT chemotaxis protein
IKDGHLII_02344 1.2e-235 mcpA NT chemotaxis protein
IKDGHLII_02345 7.8e-224 mcpA NT chemotaxis protein
IKDGHLII_02346 2.6e-235 mcpA NT chemotaxis protein
IKDGHLII_02347 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
IKDGHLII_02348 4.7e-185 ygjR S Oxidoreductase
IKDGHLII_02349 3.8e-194 yubA S transporter activity
IKDGHLII_02350 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IKDGHLII_02352 3.8e-17
IKDGHLII_02354 6.8e-14
IKDGHLII_02356 7.6e-131 S Aspartate phosphatase response regulator
IKDGHLII_02360 1e-48 yjcN
IKDGHLII_02361 1.4e-118 G Cupin
IKDGHLII_02362 1.6e-216 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IKDGHLII_02363 1.5e-144 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IKDGHLII_02364 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
IKDGHLII_02365 7.9e-94 yuaB
IKDGHLII_02366 8.6e-96 yuaC K Belongs to the GbsR family
IKDGHLII_02367 9.4e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
IKDGHLII_02368 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
IKDGHLII_02369 2.5e-109 yuaD S MOSC domain
IKDGHLII_02370 6.9e-73 yuaE S DinB superfamily
IKDGHLII_02371 7.3e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
IKDGHLII_02372 5e-178 yuaG 3.4.21.72 S protein conserved in bacteria
IKDGHLII_02373 8.2e-97 thiT S Thiamine transporter protein (Thia_YuaJ)
IKDGHLII_02374 3.4e-39 S COG NOG14552 non supervised orthologous group
IKDGHLII_02379 1.6e-08
IKDGHLII_02386 1.3e-09
IKDGHLII_02387 7.8e-08
IKDGHLII_02396 4.5e-77 tspO T membrane
IKDGHLII_02397 2.4e-130 dksA T COG1734 DnaK suppressor protein
IKDGHLII_02398 5.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
IKDGHLII_02399 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IKDGHLII_02400 2.7e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IKDGHLII_02401 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IKDGHLII_02402 4.1e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IKDGHLII_02403 3.5e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IKDGHLII_02404 2e-23 S Domain of Unknown Function (DUF1540)
IKDGHLII_02405 9.9e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IKDGHLII_02406 1.5e-239 cydA 1.10.3.14 C oxidase, subunit
IKDGHLII_02407 7.9e-41 rpmE2 J Ribosomal protein L31
IKDGHLII_02408 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IKDGHLII_02409 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IKDGHLII_02410 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IKDGHLII_02411 5.1e-75 ytkA S YtkA-like
IKDGHLII_02413 7.8e-76 dps P Belongs to the Dps family
IKDGHLII_02414 5e-61 ytkC S Bacteriophage holin family
IKDGHLII_02415 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
IKDGHLII_02416 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IKDGHLII_02417 3.2e-144 ytlC P ABC transporter
IKDGHLII_02418 9.9e-183 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IKDGHLII_02419 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IKDGHLII_02420 1.6e-38 ytmB S Protein of unknown function (DUF2584)
IKDGHLII_02421 1.2e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IKDGHLII_02422 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IKDGHLII_02423 0.0 asnB 6.3.5.4 E Asparagine synthase
IKDGHLII_02424 6.3e-260 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
IKDGHLII_02425 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IKDGHLII_02426 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
IKDGHLII_02427 1.6e-210 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
IKDGHLII_02428 1.5e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
IKDGHLII_02430 2.8e-105 ytqB J Putative rRNA methylase
IKDGHLII_02431 1.1e-189 yhcC S Fe-S oxidoreductase
IKDGHLII_02432 7.7e-281 norB EGP COG0477 Permeases of the major facilitator superfamily
IKDGHLII_02433 6.8e-193 K helix_turn_helix, Arsenical Resistance Operon Repressor
IKDGHLII_02434 7.4e-40 ytzC S Protein of unknown function (DUF2524)
IKDGHLII_02436 3.9e-66 ytrA K GntR family transcriptional regulator
IKDGHLII_02437 1.9e-161 ytrB P abc transporter atp-binding protein
IKDGHLII_02438 2e-164 S ABC-2 family transporter protein
IKDGHLII_02439 3.5e-172 P ABC-2 family transporter protein
IKDGHLII_02440 1.8e-152
IKDGHLII_02441 3.8e-125 ytrE V ABC transporter, ATP-binding protein
IKDGHLII_02442 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
IKDGHLII_02443 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKDGHLII_02444 1.3e-177 T PhoQ Sensor
IKDGHLII_02445 4.9e-134 bceA V ABC transporter, ATP-binding protein
IKDGHLII_02446 0.0 bceB V ABC transporter (permease)
IKDGHLII_02447 1.4e-122 ywaF S Integral membrane protein
IKDGHLII_02448 2.3e-207 yttB EGP Major facilitator Superfamily
IKDGHLII_02449 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IKDGHLII_02450 1.2e-52 ytvB S Protein of unknown function (DUF4257)
IKDGHLII_02451 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IKDGHLII_02452 5.6e-52 ytwF P Sulfurtransferase
IKDGHLII_02453 8.7e-84 M Acetyltransferase (GNAT) domain
IKDGHLII_02454 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IKDGHLII_02455 5.3e-142 amyC P ABC transporter (permease)
IKDGHLII_02456 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
IKDGHLII_02457 4.9e-243 msmE G Bacterial extracellular solute-binding protein
IKDGHLII_02458 2.8e-185 msmR K Transcriptional regulator
IKDGHLII_02459 9e-26 yteV S Sporulation protein Cse60
IKDGHLII_02460 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
IKDGHLII_02461 5.7e-236 ytfP S HI0933-like protein
IKDGHLII_02462 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKDGHLII_02463 2.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IKDGHLII_02464 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
IKDGHLII_02465 3.7e-128 ythP V ABC transporter
IKDGHLII_02466 1e-215 ythQ U Bacterial ABC transporter protein EcsB
IKDGHLII_02467 1.3e-227 pbuO S permease
IKDGHLII_02468 1.4e-267 pepV 3.5.1.18 E Dipeptidase
IKDGHLII_02469 3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IKDGHLII_02470 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IKDGHLII_02471 1.7e-165 ytlQ
IKDGHLII_02472 1.7e-176 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IKDGHLII_02473 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
IKDGHLII_02474 3.5e-45 ytzH S YtzH-like protein
IKDGHLII_02475 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IKDGHLII_02476 2.1e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
IKDGHLII_02477 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
IKDGHLII_02478 1.7e-51 ytzB S small secreted protein
IKDGHLII_02479 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IKDGHLII_02480 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
IKDGHLII_02481 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IKDGHLII_02482 1.9e-147 ytpQ S Belongs to the UPF0354 family
IKDGHLII_02483 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IKDGHLII_02484 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IKDGHLII_02485 5.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IKDGHLII_02486 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IKDGHLII_02487 1.7e-16 ytxH S COG4980 Gas vesicle protein
IKDGHLII_02488 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
IKDGHLII_02489 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IKDGHLII_02490 2.4e-181 ccpA K catabolite control protein A
IKDGHLII_02491 6.6e-145 motA N flagellar motor
IKDGHLII_02492 3.7e-120 motS N Flagellar motor protein
IKDGHLII_02493 4e-228 acuC BQ histone deacetylase
IKDGHLII_02494 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
IKDGHLII_02495 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IKDGHLII_02496 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IKDGHLII_02497 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IKDGHLII_02498 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
IKDGHLII_02499 2.6e-124 azlC E AzlC protein
IKDGHLII_02500 2.8e-148 K Transcriptional regulator
IKDGHLII_02501 1.6e-149 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IKDGHLII_02502 5.2e-136 E GDSL-like Lipase/Acylhydrolase family
IKDGHLII_02503 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
IKDGHLII_02504 2.5e-09
IKDGHLII_02505 5e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IKDGHLII_02506 1.7e-99 yokH G SMI1 / KNR4 family
IKDGHLII_02507 1.6e-252 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IKDGHLII_02508 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IKDGHLII_02509 2.3e-283 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
IKDGHLII_02510 3.5e-85 ytsP 1.8.4.14 T GAF domain-containing protein
IKDGHLII_02511 7.7e-109 yttP K Transcriptional regulator
IKDGHLII_02512 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IKDGHLII_02513 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IKDGHLII_02514 2.6e-239 braB E Component of the transport system for branched-chain amino acids
IKDGHLII_02515 3.5e-208 iscS2 2.8.1.7 E Cysteine desulfurase
IKDGHLII_02516 1.1e-223 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IKDGHLII_02517 3.9e-31 sspB S spore protein
IKDGHLII_02518 2.1e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IKDGHLII_02519 1.5e-310 ytcJ S amidohydrolase
IKDGHLII_02520 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IKDGHLII_02521 6.4e-182 sppA OU signal peptide peptidase SppA
IKDGHLII_02522 4.5e-88 yteJ S RDD family
IKDGHLII_02523 1e-93 ytfI S Protein of unknown function (DUF2953)
IKDGHLII_02524 1.6e-60 ytfJ S Sporulation protein YtfJ
IKDGHLII_02525 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IKDGHLII_02526 9.1e-181 ytxK 2.1.1.72 L DNA methylase
IKDGHLII_02527 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IKDGHLII_02528 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IKDGHLII_02529 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IKDGHLII_02530 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
IKDGHLII_02532 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKDGHLII_02533 3.6e-128 ytkL S Belongs to the UPF0173 family
IKDGHLII_02534 1.6e-236 ytoI K transcriptional regulator containing CBS domains
IKDGHLII_02535 1.5e-46 ytpI S YtpI-like protein
IKDGHLII_02536 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
IKDGHLII_02537 5.8e-23
IKDGHLII_02538 4.3e-86 ytrI
IKDGHLII_02539 9.2e-56 ytrH S Sporulation protein YtrH
IKDGHLII_02540 0.0 dnaE 2.7.7.7 L DNA polymerase
IKDGHLII_02541 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
IKDGHLII_02542 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IKDGHLII_02543 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IKDGHLII_02544 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IKDGHLII_02545 2.9e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IKDGHLII_02546 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
IKDGHLII_02547 2.4e-193 ytvI S sporulation integral membrane protein YtvI
IKDGHLII_02548 1.1e-72 yeaL S membrane
IKDGHLII_02549 2.1e-46 yjdF S Protein of unknown function (DUF2992)
IKDGHLII_02550 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
IKDGHLII_02551 1.2e-241 icd 1.1.1.42 C isocitrate
IKDGHLII_02552 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
IKDGHLII_02553 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKDGHLII_02554 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
IKDGHLII_02555 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IKDGHLII_02556 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IKDGHLII_02557 2.1e-106 ytaF P Probably functions as a manganese efflux pump
IKDGHLII_02558 1.7e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IKDGHLII_02559 1.7e-159 ytbE S reductase
IKDGHLII_02560 9.9e-206 ytbD EGP Major facilitator Superfamily
IKDGHLII_02561 2e-67 ytcD K Transcriptional regulator
IKDGHLII_02562 2.2e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IKDGHLII_02563 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IKDGHLII_02564 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IKDGHLII_02565 3.1e-251 dnaB L Membrane attachment protein
IKDGHLII_02566 9.5e-172 dnaI L Primosomal protein DnaI
IKDGHLII_02567 2.1e-106 ytxB S SNARE associated Golgi protein
IKDGHLII_02568 6.7e-153 ytxC S YtxC-like family
IKDGHLII_02569 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IKDGHLII_02570 3.9e-150 ysaA S HAD-hyrolase-like
IKDGHLII_02571 0.0 lytS 2.7.13.3 T Histidine kinase
IKDGHLII_02572 5.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
IKDGHLII_02573 2.9e-38 lrgA S effector of murein hydrolase LrgA
IKDGHLII_02574 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IKDGHLII_02575 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IKDGHLII_02576 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IKDGHLII_02577 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IKDGHLII_02578 2.6e-42 ysdA S Membrane
IKDGHLII_02579 1.9e-65 ysdB S Sigma-w pathway protein YsdB
IKDGHLII_02580 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
IKDGHLII_02581 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IKDGHLII_02582 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IKDGHLII_02583 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
IKDGHLII_02584 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IKDGHLII_02585 7.8e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IKDGHLII_02586 1.2e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IKDGHLII_02587 2.9e-251 araN G carbohydrate transport
IKDGHLII_02588 1.1e-167 araP P PFAM binding-protein-dependent transport systems inner membrane component
IKDGHLII_02589 1.2e-144 araQ G transport system permease
IKDGHLII_02590 2.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
IKDGHLII_02591 0.0 cstA T Carbon starvation protein
IKDGHLII_02592 1.3e-254 glcF C Glycolate oxidase
IKDGHLII_02593 1.6e-258 glcD 1.1.3.15 C FAD binding domain
IKDGHLII_02594 2.7e-202 ysfB KT regulator
IKDGHLII_02595 2e-32 sspI S Belongs to the SspI family
IKDGHLII_02596 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IKDGHLII_02597 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IKDGHLII_02598 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IKDGHLII_02599 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IKDGHLII_02600 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IKDGHLII_02601 3.6e-83 cvpA S membrane protein, required for colicin V production
IKDGHLII_02602 0.0 polX L COG1796 DNA polymerase IV (family X)
IKDGHLII_02603 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IKDGHLII_02604 4.7e-67 yshE S membrane
IKDGHLII_02605 8.6e-89 ywbB S Protein of unknown function (DUF2711)
IKDGHLII_02606 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IKDGHLII_02607 1e-102 fadR K Transcriptional regulator
IKDGHLII_02608 7e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IKDGHLII_02609 1.7e-137 etfB C Electron transfer flavoprotein
IKDGHLII_02610 6e-177 etfA C Electron transfer flavoprotein
IKDGHLII_02611 4.3e-299 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
IKDGHLII_02612 2.5e-52 trxA O Belongs to the thioredoxin family
IKDGHLII_02613 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IKDGHLII_02614 9.2e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IKDGHLII_02615 2e-79 yslB S Protein of unknown function (DUF2507)
IKDGHLII_02616 4.8e-108 sdhC C succinate dehydrogenase
IKDGHLII_02617 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IKDGHLII_02618 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IKDGHLII_02619 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
IKDGHLII_02620 2e-30 gerE K Transcriptional regulator
IKDGHLII_02621 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
IKDGHLII_02622 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IKDGHLII_02623 1.5e-197 gerM S COG5401 Spore germination protein
IKDGHLII_02624 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IKDGHLII_02625 4.2e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IKDGHLII_02626 5.9e-91 ysnB S Phosphoesterase
IKDGHLII_02630 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
IKDGHLII_02631 1.5e-248 hsdM 2.1.1.72 L type I restriction-modification system
IKDGHLII_02632 1.9e-123 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IKDGHLII_02635 0.0 ilvB 2.2.1.6 E Acetolactate synthase
IKDGHLII_02636 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
IKDGHLII_02637 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IKDGHLII_02638 1.8e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IKDGHLII_02639 1.1e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IKDGHLII_02640 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IKDGHLII_02641 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IKDGHLII_02642 1e-187 ysoA H Tetratricopeptide repeat
IKDGHLII_02643 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IKDGHLII_02644 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IKDGHLII_02645 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
IKDGHLII_02646 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IKDGHLII_02647 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
IKDGHLII_02648 3.8e-87 ysxD
IKDGHLII_02649 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IKDGHLII_02650 1e-145 hemX O cytochrome C
IKDGHLII_02651 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IKDGHLII_02652 2.3e-139 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IKDGHLII_02653 8.7e-184 hemB 4.2.1.24 H Belongs to the ALAD family
IKDGHLII_02654 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IKDGHLII_02655 4e-227 spoVID M stage VI sporulation protein D
IKDGHLII_02656 9.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IKDGHLII_02657 2.1e-25
IKDGHLII_02658 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IKDGHLII_02659 2.4e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IKDGHLII_02660 1.1e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IKDGHLII_02661 2.8e-137 spoIIB S Sporulation related domain
IKDGHLII_02662 2.1e-97 maf D septum formation protein Maf
IKDGHLII_02663 5.9e-126 radC E Belongs to the UPF0758 family
IKDGHLII_02664 4e-184 mreB D Rod shape-determining protein MreB
IKDGHLII_02665 3.6e-157 mreC M Involved in formation and maintenance of cell shape
IKDGHLII_02666 5.4e-84 mreD M shape-determining protein
IKDGHLII_02667 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IKDGHLII_02668 2.3e-142 minD D Belongs to the ParA family
IKDGHLII_02669 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
IKDGHLII_02670 7.8e-160 spoIVFB S Stage IV sporulation protein
IKDGHLII_02671 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
IKDGHLII_02672 3.2e-56 ysxB J ribosomal protein
IKDGHLII_02673 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IKDGHLII_02674 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
IKDGHLII_02675 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IKDGHLII_02676 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
IKDGHLII_02677 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
IKDGHLII_02678 3e-93 niaR S small molecule binding protein (contains 3H domain)
IKDGHLII_02679 1.6e-221 nifS 2.8.1.7 E Cysteine desulfurase
IKDGHLII_02680 1.1e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
IKDGHLII_02681 7.6e-152 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
IKDGHLII_02682 5.9e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IKDGHLII_02683 1.2e-126 safA M spore coat assembly protein SafA
IKDGHLII_02684 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IKDGHLII_02686 3.7e-93 bofC S BofC C-terminal domain
IKDGHLII_02687 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IKDGHLII_02688 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IKDGHLII_02689 1.6e-20 yrzS S Protein of unknown function (DUF2905)
IKDGHLII_02690 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IKDGHLII_02691 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IKDGHLII_02692 2.5e-37 yajC U Preprotein translocase subunit YajC
IKDGHLII_02693 2.4e-60 yrzE S Protein of unknown function (DUF3792)
IKDGHLII_02694 9.5e-110 yrbG S membrane
IKDGHLII_02695 4.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKDGHLII_02696 8.5e-50 yrzD S Post-transcriptional regulator
IKDGHLII_02697 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IKDGHLII_02698 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
IKDGHLII_02699 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
IKDGHLII_02700 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IKDGHLII_02701 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IKDGHLII_02702 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IKDGHLII_02703 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IKDGHLII_02704 1.4e-273 lytH 3.5.1.28 M COG3103 SH3 domain protein
IKDGHLII_02707 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
IKDGHLII_02708 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IKDGHLII_02709 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IKDGHLII_02710 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IKDGHLII_02711 7.8e-64 cymR K Transcriptional regulator
IKDGHLII_02712 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
IKDGHLII_02713 1.2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IKDGHLII_02714 2.2e-18 S COG0457 FOG TPR repeat
IKDGHLII_02715 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IKDGHLII_02716 3.4e-82 yrrD S protein conserved in bacteria
IKDGHLII_02717 2.9e-30 yrzR
IKDGHLII_02718 2.1e-08 S Protein of unknown function (DUF3918)
IKDGHLII_02719 4.9e-106 glnP P ABC transporter
IKDGHLII_02720 6.1e-109 gluC P ABC transporter
IKDGHLII_02721 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
IKDGHLII_02722 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IKDGHLII_02723 2e-162 yrrI S AI-2E family transporter
IKDGHLII_02724 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IKDGHLII_02725 8.5e-41 yrzL S Belongs to the UPF0297 family
IKDGHLII_02726 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IKDGHLII_02727 7.1e-46 yrzB S Belongs to the UPF0473 family
IKDGHLII_02728 4.1e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IKDGHLII_02729 2.3e-116 yrrM 2.1.1.104 S O-methyltransferase
IKDGHLII_02730 2.9e-173 yegQ O Peptidase U32
IKDGHLII_02731 6.1e-246 yegQ O COG0826 Collagenase and related proteases
IKDGHLII_02732 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
IKDGHLII_02733 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IKDGHLII_02734 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
IKDGHLII_02735 8.1e-70 yrrS S Protein of unknown function (DUF1510)
IKDGHLII_02736 4.1e-27 yrzA S Protein of unknown function (DUF2536)
IKDGHLII_02737 2.3e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
IKDGHLII_02738 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IKDGHLII_02739 3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
IKDGHLII_02740 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IKDGHLII_02741 5.1e-34 yrhC S YrhC-like protein
IKDGHLII_02742 7e-81 yrhD S Protein of unknown function (DUF1641)
IKDGHLII_02743 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
IKDGHLII_02744 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
IKDGHLII_02745 3e-142 focA P Formate nitrite
IKDGHLII_02747 7.1e-79 yrhH Q methyltransferase
IKDGHLII_02748 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
IKDGHLII_02749 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IKDGHLII_02750 3.2e-212 ynfM EGP Major facilitator Superfamily
IKDGHLII_02751 4.1e-164 yybE K Transcriptional regulator
IKDGHLII_02752 1.7e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IKDGHLII_02753 3.3e-180 romA S Beta-lactamase superfamily domain
IKDGHLII_02754 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
IKDGHLII_02755 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
IKDGHLII_02756 7.6e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
IKDGHLII_02757 5.9e-129 glvR K Helix-turn-helix domain, rpiR family
IKDGHLII_02758 3.9e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
IKDGHLII_02759 3.9e-54 S hydrolase
IKDGHLII_02760 9e-81 S hydrolase
IKDGHLII_02762 1.5e-91 yrdA S DinB family
IKDGHLII_02763 1.1e-81 yyaR K Acetyltransferase (GNAT) domain
IKDGHLII_02764 4e-219 tetL EGP Major facilitator Superfamily
IKDGHLII_02766 1.4e-95 adk 2.7.4.3 F adenylate kinase activity
IKDGHLII_02767 3.2e-81 ydeE K AraC family transcriptional regulator
IKDGHLII_02768 3.9e-58 ydeE K AraC family transcriptional regulator
IKDGHLII_02769 3.6e-91 K Transcriptional regulator PadR-like family
IKDGHLII_02770 1.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
IKDGHLII_02771 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKDGHLII_02772 1.1e-199 EGP Major facilitator Superfamily
IKDGHLII_02773 8e-106 yqeD S SNARE associated Golgi protein
IKDGHLII_02774 2.9e-139 3.5.1.104 G Polysaccharide deacetylase
IKDGHLII_02775 2.5e-138 yqeF E GDSL-like Lipase/Acylhydrolase
IKDGHLII_02777 7.6e-94 yqeG S hydrolase of the HAD superfamily
IKDGHLII_02778 2.2e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IKDGHLII_02779 1.2e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IKDGHLII_02780 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
IKDGHLII_02781 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IKDGHLII_02782 2.2e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IKDGHLII_02783 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IKDGHLII_02784 1.1e-138 yqeM Q Methyltransferase
IKDGHLII_02785 3.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IKDGHLII_02786 8.9e-102 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IKDGHLII_02787 8e-105 comEB 3.5.4.12 F ComE operon protein 2
IKDGHLII_02788 0.0 comEC S Competence protein ComEC
IKDGHLII_02789 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
IKDGHLII_02790 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
IKDGHLII_02791 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IKDGHLII_02792 9.2e-220 spoIIP M stage II sporulation protein P
IKDGHLII_02793 2.5e-53 yqxA S Protein of unknown function (DUF3679)
IKDGHLII_02794 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IKDGHLII_02795 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
IKDGHLII_02796 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IKDGHLII_02797 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IKDGHLII_02798 0.0 dnaK O Heat shock 70 kDa protein
IKDGHLII_02799 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IKDGHLII_02800 6.6e-173 prmA J Methylates ribosomal protein L11
IKDGHLII_02801 3.9e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IKDGHLII_02802 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
IKDGHLII_02803 3.3e-156 yqeW P COG1283 Na phosphate symporter
IKDGHLII_02804 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IKDGHLII_02805 8e-68 yqeY S Yqey-like protein
IKDGHLII_02806 8.3e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
IKDGHLII_02807 3.8e-118 yqfA S UPF0365 protein
IKDGHLII_02808 1.9e-42 yqfB
IKDGHLII_02809 9.3e-46 yqfC S sporulation protein YqfC
IKDGHLII_02810 5.7e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
IKDGHLII_02811 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
IKDGHLII_02812 0.0 yqfF S membrane-associated HD superfamily hydrolase
IKDGHLII_02813 9.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IKDGHLII_02814 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IKDGHLII_02815 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IKDGHLII_02816 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IKDGHLII_02817 1.8e-16 S YqzL-like protein
IKDGHLII_02818 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
IKDGHLII_02819 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IKDGHLII_02820 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IKDGHLII_02821 4.5e-112 ccpN K CBS domain
IKDGHLII_02822 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IKDGHLII_02823 6.1e-88 yaiI S Belongs to the UPF0178 family
IKDGHLII_02824 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IKDGHLII_02825 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IKDGHLII_02826 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
IKDGHLII_02827 9.9e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
IKDGHLII_02828 2.4e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IKDGHLII_02829 2.5e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IKDGHLII_02830 3.7e-43 yqfQ S YqfQ-like protein
IKDGHLII_02831 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IKDGHLII_02832 1.4e-164 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IKDGHLII_02833 9.3e-37 yqfT S Protein of unknown function (DUF2624)
IKDGHLII_02834 5.3e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IKDGHLII_02835 2.9e-72 zur P Belongs to the Fur family
IKDGHLII_02836 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
IKDGHLII_02837 2.3e-52 yqfX S membrane
IKDGHLII_02838 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IKDGHLII_02839 2.6e-46 yqfZ M LysM domain
IKDGHLII_02840 1.1e-130 yqgB S Protein of unknown function (DUF1189)
IKDGHLII_02841 2.2e-71 yqgC S protein conserved in bacteria
IKDGHLII_02842 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
IKDGHLII_02843 3.4e-228 yqgE EGP Major facilitator superfamily
IKDGHLII_02844 0.0 pbpA 3.4.16.4 M penicillin-binding protein
IKDGHLII_02845 7.6e-158 pstS P Phosphate
IKDGHLII_02846 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
IKDGHLII_02847 2.9e-154 pstA P Phosphate transport system permease
IKDGHLII_02848 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IKDGHLII_02849 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IKDGHLII_02850 3.2e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IKDGHLII_02851 1.2e-50 yqzD
IKDGHLII_02852 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IKDGHLII_02853 1e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IKDGHLII_02854 4e-07 yqgO
IKDGHLII_02855 1e-230 nhaC C Na H antiporter
IKDGHLII_02856 6.5e-28 yqgQ S Protein conserved in bacteria
IKDGHLII_02857 7.5e-180 glcK 2.7.1.2 G Glucokinase
IKDGHLII_02858 1.4e-217 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
IKDGHLII_02859 3.3e-197 yqgU
IKDGHLII_02860 4.5e-49 yqgV S Thiamine-binding protein
IKDGHLII_02861 5.4e-20 yqgW S Protein of unknown function (DUF2759)
IKDGHLII_02862 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IKDGHLII_02863 3.1e-37 yqgY S Protein of unknown function (DUF2626)
IKDGHLII_02864 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
IKDGHLII_02866 6.5e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IKDGHLII_02867 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IKDGHLII_02868 1.2e-185 corA P Mg2 transporter protein
IKDGHLII_02869 1.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IKDGHLII_02870 7.8e-183 comGB NU COG1459 Type II secretory pathway, component PulF
IKDGHLII_02871 8.9e-50 comGC U Required for transformation and DNA binding
IKDGHLII_02872 1.7e-70 gspH NU Tfp pilus assembly protein FimT
IKDGHLII_02873 2.6e-20 comGE
IKDGHLII_02874 1.6e-64 comGF U Putative Competence protein ComGF
IKDGHLII_02875 2.1e-61 S ComG operon protein 7
IKDGHLII_02876 2.3e-26 yqzE S YqzE-like protein
IKDGHLII_02877 1.1e-53 yqzG S Protein of unknown function (DUF3889)
IKDGHLII_02878 1.2e-120 yqxM
IKDGHLII_02879 1.9e-69 sipW 3.4.21.89 U Signal peptidase
IKDGHLII_02880 1.6e-140 tasA S Cell division protein FtsN
IKDGHLII_02881 7.8e-55 sinR K transcriptional
IKDGHLII_02882 5.2e-23 sinI S Anti-repressor SinI
IKDGHLII_02883 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
IKDGHLII_02884 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IKDGHLII_02885 1.5e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
IKDGHLII_02886 5.1e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IKDGHLII_02887 1.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IKDGHLII_02888 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
IKDGHLII_02889 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IKDGHLII_02890 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IKDGHLII_02891 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
IKDGHLII_02892 5.8e-62 yqhP
IKDGHLII_02893 8e-174 yqhQ S Protein of unknown function (DUF1385)
IKDGHLII_02894 3.7e-88 yqhR S Conserved membrane protein YqhR
IKDGHLII_02895 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IKDGHLII_02896 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IKDGHLII_02897 1.8e-36 yqhV S Protein of unknown function (DUF2619)
IKDGHLII_02898 7.2e-172 spoIIIAA S stage III sporulation protein AA
IKDGHLII_02899 4.6e-83 spoIIIAB S Stage III sporulation protein
IKDGHLII_02900 7.6e-29 spoIIIAC S stage III sporulation protein AC
IKDGHLII_02901 2.5e-41 spoIIIAD S Stage III sporulation protein AD
IKDGHLII_02902 6.3e-200 spoIIIAE S stage III sporulation protein AE
IKDGHLII_02903 7.6e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
IKDGHLII_02904 2.5e-116 spoIIIAG S stage III sporulation protein AG
IKDGHLII_02905 2.5e-62 spoIIIAH S SpoIIIAH-like protein
IKDGHLII_02906 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IKDGHLII_02907 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IKDGHLII_02908 8.1e-67 yqhY S protein conserved in bacteria
IKDGHLII_02909 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IKDGHLII_02910 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IKDGHLII_02911 1.3e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IKDGHLII_02912 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IKDGHLII_02913 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IKDGHLII_02914 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IKDGHLII_02915 1.3e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
IKDGHLII_02916 3.9e-78 argR K Regulates arginine biosynthesis genes
IKDGHLII_02917 0.0 recN L May be involved in recombinational repair of damaged DNA
IKDGHLII_02918 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
IKDGHLII_02919 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IKDGHLII_02920 2.6e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IKDGHLII_02923 1.3e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IKDGHLII_02925 5.8e-112 K Protein of unknown function (DUF1232)
IKDGHLII_02926 1.5e-101 ytaF P Probably functions as a manganese efflux pump
IKDGHLII_02927 1.2e-16
IKDGHLII_02928 9.7e-104 amiC 3.5.1.28 M Cell wall hydrolase autolysin
IKDGHLII_02929 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IKDGHLII_02930 8.3e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
IKDGHLII_02931 2.2e-154 hbdA 1.1.1.157 I Dehydrogenase
IKDGHLII_02932 2.3e-204 mmgC I acyl-CoA dehydrogenase
IKDGHLII_02933 9.4e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
IKDGHLII_02934 9.2e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
IKDGHLII_02935 2.4e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IKDGHLII_02936 3.2e-34 yqzF S Protein of unknown function (DUF2627)
IKDGHLII_02937 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
IKDGHLII_02938 8.9e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
IKDGHLII_02939 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
IKDGHLII_02940 1.6e-205 buk 2.7.2.7 C Belongs to the acetokinase family
IKDGHLII_02941 2.9e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IKDGHLII_02942 2.1e-161 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IKDGHLII_02943 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IKDGHLII_02944 6.8e-189 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IKDGHLII_02945 1.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IKDGHLII_02946 1e-75 yqiW S Belongs to the UPF0403 family
IKDGHLII_02947 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
IKDGHLII_02948 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
IKDGHLII_02949 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IKDGHLII_02950 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
IKDGHLII_02951 3.1e-95 yqjB S protein conserved in bacteria
IKDGHLII_02953 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
IKDGHLII_02954 3.2e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IKDGHLII_02955 1.8e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
IKDGHLII_02956 5e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IKDGHLII_02957 2.4e-25 yqzJ
IKDGHLII_02958 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKDGHLII_02959 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IKDGHLII_02960 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IKDGHLII_02961 2.3e-170 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IKDGHLII_02962 4.8e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IKDGHLII_02963 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IKDGHLII_02964 5.5e-50 S GlpM protein
IKDGHLII_02965 2.7e-160 K LysR substrate binding domain
IKDGHLII_02966 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
IKDGHLII_02967 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IKDGHLII_02970 1.7e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IKDGHLII_02971 1.1e-127 IQ reductase
IKDGHLII_02972 0.0 pksJ Q Polyketide synthase of type I
IKDGHLII_02973 0.0 1.1.1.320 Q Polyketide synthase of type I
IKDGHLII_02974 0.0 Q Polyketide synthase of type I
IKDGHLII_02975 0.0 pksJ Q Polyketide synthase of type I
IKDGHLII_02976 0.0 pfaA Q Polyketide synthase of type I
IKDGHLII_02977 0.0 Q Polyketide synthase of type I
IKDGHLII_02978 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IKDGHLII_02979 3.1e-220 eryK 1.14.13.154 C Cytochrome P450
IKDGHLII_02980 1.7e-238 pksG 2.3.3.10 I synthase
IKDGHLII_02981 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IKDGHLII_02982 2e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IKDGHLII_02983 4e-173 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
IKDGHLII_02984 1.6e-140 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
IKDGHLII_02985 5.3e-248 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IKDGHLII_02986 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IKDGHLII_02987 2.5e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IKDGHLII_02989 1.3e-185 yueF S transporter activity
IKDGHLII_02991 2.1e-55 S YolD-like protein
IKDGHLII_02992 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IKDGHLII_02993 8.7e-89 yqjY K acetyltransferase
IKDGHLII_02994 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
IKDGHLII_02995 1.2e-172 yqkA K GrpB protein
IKDGHLII_02996 7.7e-61 yqkB S Belongs to the HesB IscA family
IKDGHLII_02997 3.2e-39 yqkC S Protein of unknown function (DUF2552)
IKDGHLII_02998 9e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
IKDGHLII_03000 2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
IKDGHLII_03002 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
IKDGHLII_03003 1.2e-219 yqxK 3.6.4.12 L DNA helicase
IKDGHLII_03004 1e-57 ansR K Transcriptional regulator
IKDGHLII_03005 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
IKDGHLII_03006 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
IKDGHLII_03007 1.6e-239 mleN C Na H antiporter
IKDGHLII_03008 3.8e-243 mleA 1.1.1.38 C malic enzyme
IKDGHLII_03009 5.7e-22
IKDGHLII_03010 3.9e-34 yqkK
IKDGHLII_03012 7.2e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IKDGHLII_03013 1.9e-80 fur P Belongs to the Fur family
IKDGHLII_03014 3.7e-37 S Protein of unknown function (DUF4227)
IKDGHLII_03015 8.2e-165 xerD L recombinase XerD
IKDGHLII_03016 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IKDGHLII_03017 2.4e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IKDGHLII_03018 1.1e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
IKDGHLII_03019 1.9e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
IKDGHLII_03020 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IKDGHLII_03021 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKDGHLII_03022 1.8e-110 spoVAA S Stage V sporulation protein AA
IKDGHLII_03023 5.1e-60 spoVAB S Stage V sporulation protein AB
IKDGHLII_03024 6e-79 spoVAC S stage V sporulation protein AC
IKDGHLII_03025 1.2e-188 spoVAD I Stage V sporulation protein AD
IKDGHLII_03026 5e-57 spoVAEB S stage V sporulation protein
IKDGHLII_03027 1.1e-109 spoVAEA S stage V sporulation protein
IKDGHLII_03028 3.2e-270 spoVAF EG Stage V sporulation protein AF
IKDGHLII_03029 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IKDGHLII_03030 1.9e-153 ypuA S Secreted protein
IKDGHLII_03031 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IKDGHLII_03032 1.2e-80 ccdC1 O Protein of unknown function (DUF1453)
IKDGHLII_03033 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IKDGHLII_03034 1.4e-48 ypuD
IKDGHLII_03035 3.1e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IKDGHLII_03036 1.1e-110 ribE 2.5.1.9 H Riboflavin synthase
IKDGHLII_03037 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IKDGHLII_03038 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IKDGHLII_03039 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IKDGHLII_03040 1.7e-93 ypuF S Domain of unknown function (DUF309)
IKDGHLII_03042 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IKDGHLII_03043 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IKDGHLII_03044 3.8e-93 ypuI S Protein of unknown function (DUF3907)
IKDGHLII_03045 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
IKDGHLII_03046 2e-103 spmA S Spore maturation protein
IKDGHLII_03047 1.3e-88 spmB S Spore maturation protein
IKDGHLII_03048 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IKDGHLII_03049 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IKDGHLII_03050 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
IKDGHLII_03051 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IKDGHLII_03052 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IKDGHLII_03053 0.0 resE 2.7.13.3 T Histidine kinase
IKDGHLII_03054 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
IKDGHLII_03055 5.2e-193 rsiX
IKDGHLII_03056 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IKDGHLII_03057 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IKDGHLII_03058 3.6e-41 fer C Ferredoxin
IKDGHLII_03059 1.9e-192 ypbB 5.1.3.1 S protein conserved in bacteria
IKDGHLII_03060 7.5e-269 recQ 3.6.4.12 L DNA helicase
IKDGHLII_03061 4e-99 ypbD S metal-dependent membrane protease
IKDGHLII_03062 9.9e-74 ypbE M Lysin motif
IKDGHLII_03063 5.7e-85 ypbF S Protein of unknown function (DUF2663)
IKDGHLII_03064 7.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
IKDGHLII_03065 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IKDGHLII_03066 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IKDGHLII_03067 3.4e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
IKDGHLII_03068 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
IKDGHLII_03069 3e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
IKDGHLII_03070 3e-251 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
IKDGHLII_03071 2.2e-58 ypfA M Flagellar protein YcgR
IKDGHLII_03072 1.4e-12 S Family of unknown function (DUF5359)
IKDGHLII_03073 8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IKDGHLII_03074 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
IKDGHLII_03075 1.7e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IKDGHLII_03076 4.7e-08 S YpzI-like protein
IKDGHLII_03077 1.6e-103 yphA
IKDGHLII_03078 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IKDGHLII_03079 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IKDGHLII_03080 2.5e-16 yphE S Protein of unknown function (DUF2768)
IKDGHLII_03081 5.3e-133 yphF
IKDGHLII_03082 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IKDGHLII_03083 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IKDGHLII_03084 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
IKDGHLII_03085 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IKDGHLII_03086 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IKDGHLII_03087 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IKDGHLII_03088 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IKDGHLII_03089 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IKDGHLII_03090 4.7e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
IKDGHLII_03091 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IKDGHLII_03092 1.2e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IKDGHLII_03093 9e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IKDGHLII_03094 4.2e-289 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IKDGHLII_03095 3.1e-152 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IKDGHLII_03096 1.2e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IKDGHLII_03097 7.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IKDGHLII_03098 2.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IKDGHLII_03099 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IKDGHLII_03100 1.9e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IKDGHLII_03101 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IKDGHLII_03102 8.1e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IKDGHLII_03103 3.5e-233 S COG0457 FOG TPR repeat
IKDGHLII_03104 2.1e-99 ypiB S Belongs to the UPF0302 family
IKDGHLII_03105 3.2e-77 ypiF S Protein of unknown function (DUF2487)
IKDGHLII_03106 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
IKDGHLII_03107 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
IKDGHLII_03108 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
IKDGHLII_03109 2.9e-105 ypjA S membrane
IKDGHLII_03110 9.5e-141 ypjB S sporulation protein
IKDGHLII_03111 2.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
IKDGHLII_03112 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
IKDGHLII_03113 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
IKDGHLII_03114 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IKDGHLII_03115 1.2e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
IKDGHLII_03116 1.9e-132 bshB1 S proteins, LmbE homologs
IKDGHLII_03117 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
IKDGHLII_03118 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IKDGHLII_03119 6.2e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IKDGHLII_03120 1.7e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IKDGHLII_03121 2.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IKDGHLII_03122 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IKDGHLII_03123 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IKDGHLII_03124 6.7e-23 ypmA S Protein of unknown function (DUF4264)
IKDGHLII_03125 1.5e-80 ypmB S protein conserved in bacteria
IKDGHLII_03126 4.1e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IKDGHLII_03127 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
IKDGHLII_03128 3e-130 dnaD L DNA replication protein DnaD
IKDGHLII_03129 2.7e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IKDGHLII_03130 2.5e-91 ypoC
IKDGHLII_03131 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IKDGHLII_03132 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IKDGHLII_03133 2.6e-188 yppC S Protein of unknown function (DUF2515)
IKDGHLII_03136 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
IKDGHLII_03138 2.1e-49 yppG S YppG-like protein
IKDGHLII_03139 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
IKDGHLII_03140 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
IKDGHLII_03141 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IKDGHLII_03142 4.7e-219 yprB L RNase_H superfamily
IKDGHLII_03144 9.9e-33 cotD S Inner spore coat protein D
IKDGHLII_03145 1.6e-97 ypsA S Belongs to the UPF0398 family
IKDGHLII_03146 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IKDGHLII_03147 2.7e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IKDGHLII_03148 6.6e-22 S YpzG-like protein
IKDGHLII_03150 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
IKDGHLII_03151 1.3e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IKDGHLII_03152 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IKDGHLII_03153 2.9e-235 pbuX F xanthine
IKDGHLII_03155 9.4e-98 yrdC 3.5.1.19 Q Isochorismatase family
IKDGHLII_03156 1.2e-56 ydfR S Protein of unknown function (DUF421)
IKDGHLII_03157 3.9e-22 ydfR S Protein of unknown function (DUF421)
IKDGHLII_03159 7.8e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
IKDGHLII_03160 1.3e-105 J Acetyltransferase (GNAT) domain
IKDGHLII_03161 6.1e-202 bcsA Q Naringenin-chalcone synthase
IKDGHLII_03162 1.1e-89 ypbQ S protein conserved in bacteria
IKDGHLII_03163 0.0 ypbR S Dynamin family
IKDGHLII_03164 2.2e-38 ypbS S Protein of unknown function (DUF2533)
IKDGHLII_03166 2.2e-162 polA 2.7.7.7 L 5'3' exonuclease
IKDGHLII_03168 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
IKDGHLII_03169 1.7e-117 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IKDGHLII_03170 9.1e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
IKDGHLII_03171 1.5e-28 ypeQ S Zinc-finger
IKDGHLII_03172 1.2e-36 S Protein of unknown function (DUF2564)
IKDGHLII_03173 1.3e-11 degR
IKDGHLII_03174 1e-30 cspD K Cold-shock protein
IKDGHLII_03175 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IKDGHLII_03176 3.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IKDGHLII_03177 7.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IKDGHLII_03178 3.1e-99 ypgQ S phosphohydrolase
IKDGHLII_03179 2.2e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
IKDGHLII_03180 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IKDGHLII_03181 1e-75 yphP S Belongs to the UPF0403 family
IKDGHLII_03182 1.1e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
IKDGHLII_03183 2.5e-112 ypjP S YpjP-like protein
IKDGHLII_03184 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IKDGHLII_03185 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IKDGHLII_03186 2.3e-113 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IKDGHLII_03187 1.6e-109 hlyIII S protein, Hemolysin III
IKDGHLII_03188 8.3e-174 pspF K Transcriptional regulator
IKDGHLII_03189 3.7e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IKDGHLII_03190 1.4e-37 ypmP S Protein of unknown function (DUF2535)
IKDGHLII_03191 1.1e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IKDGHLII_03192 6.4e-134 ypmR E GDSL-like Lipase/Acylhydrolase
IKDGHLII_03193 6.1e-97 ypmS S protein conserved in bacteria
IKDGHLII_03194 1.4e-66 ypoP K transcriptional
IKDGHLII_03195 2.7e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IKDGHLII_03196 4.7e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IKDGHLII_03197 6.8e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
IKDGHLII_03198 1.2e-302 yokA L Recombinase
IKDGHLII_03201 8.7e-75 yokF 3.1.31.1 L RNA catabolic process
IKDGHLII_03202 1.2e-86 G SMI1-KNR4 cell-wall
IKDGHLII_03203 4.2e-202 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IKDGHLII_03204 2.9e-65 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IKDGHLII_03205 2.8e-52 S SMI1-KNR4 cell-wall
IKDGHLII_03206 3.8e-89 yokK S SMI1 / KNR4 family
IKDGHLII_03207 4.3e-29 S Acetyltransferase (GNAT) domain
IKDGHLII_03208 7e-24
IKDGHLII_03209 2e-08 S Domain of unknown function (DUF4879)
IKDGHLII_03211 7.2e-157 3.4.24.40 S amine dehydrogenase activity
IKDGHLII_03214 5e-207 S aspartate phosphatase
IKDGHLII_03215 1.1e-75 yoqH M LysM domain
IKDGHLII_03218 2.6e-08
IKDGHLII_03219 2.5e-22 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
IKDGHLII_03220 1.7e-77
IKDGHLII_03225 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
IKDGHLII_03226 4.4e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
IKDGHLII_03227 3.7e-163 cgeB S Spore maturation protein
IKDGHLII_03228 1.6e-52 cgeA
IKDGHLII_03229 2.4e-36 cgeC
IKDGHLII_03230 4.1e-242 cgeD M maturation of the outermost layer of the spore
IKDGHLII_03231 1.4e-144 yiiD K acetyltransferase
IKDGHLII_03233 2.1e-18 yosT L Bacterial transcription activator, effector binding domain
IKDGHLII_03234 1.1e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IKDGHLII_03235 8.4e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IKDGHLII_03236 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IKDGHLII_03237 9e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
IKDGHLII_03238 4.9e-154 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
IKDGHLII_03239 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
IKDGHLII_03240 9.2e-46 yokU S YokU-like protein, putative antitoxin
IKDGHLII_03241 9.1e-36 yozE S Belongs to the UPF0346 family
IKDGHLII_03242 5.5e-27 E lactoylglutathione lyase activity
IKDGHLII_03243 1.7e-125 yodN
IKDGHLII_03245 6.2e-24 yozD S YozD-like protein
IKDGHLII_03246 2.3e-102 yodM 3.6.1.27 I Acid phosphatase homologues
IKDGHLII_03247 3.3e-55 yodL S YodL-like
IKDGHLII_03249 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IKDGHLII_03250 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IKDGHLII_03251 1.9e-21 yodI
IKDGHLII_03252 8.3e-128 yodH Q Methyltransferase
IKDGHLII_03253 2.3e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IKDGHLII_03254 2.6e-132 yydK K Transcriptional regulator
IKDGHLII_03255 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IKDGHLII_03256 1.8e-278 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
IKDGHLII_03257 1.1e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IKDGHLII_03258 1.4e-19 S Protein of unknown function (DUF3311)
IKDGHLII_03259 3.8e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
IKDGHLII_03260 6.3e-108 mhqD S Carboxylesterase
IKDGHLII_03261 4.5e-106 yodC C nitroreductase
IKDGHLII_03262 3e-56 yodB K transcriptional
IKDGHLII_03263 1.5e-67 yoaQ S Evidence 4 Homologs of previously reported genes of
IKDGHLII_03264 2e-67 yodA S tautomerase
IKDGHLII_03266 7.3e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
IKDGHLII_03267 1.1e-161 rarD S -transporter
IKDGHLII_03268 4.9e-23
IKDGHLII_03269 3.7e-60 yojF S Protein of unknown function (DUF1806)
IKDGHLII_03270 3.3e-126 yojG S deacetylase
IKDGHLII_03271 2.2e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IKDGHLII_03272 4.7e-236 norM V Multidrug efflux pump
IKDGHLII_03274 1.7e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IKDGHLII_03275 6.9e-223 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
IKDGHLII_03276 2.6e-225 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IKDGHLII_03277 7.3e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IKDGHLII_03278 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
IKDGHLII_03279 0.0 yojO P Von Willebrand factor
IKDGHLII_03280 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IKDGHLII_03281 2.1e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IKDGHLII_03282 1.1e-138 S Metallo-beta-lactamase superfamily
IKDGHLII_03283 1.9e-159 yocS S -transporter
IKDGHLII_03284 8.7e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IKDGHLII_03285 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
IKDGHLII_03286 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
IKDGHLII_03287 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
IKDGHLII_03288 3.6e-31 yozC
IKDGHLII_03290 2.4e-56 yozO S Bacterial PH domain
IKDGHLII_03291 8.5e-37 yocN
IKDGHLII_03292 3.8e-44 yozN
IKDGHLII_03293 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
IKDGHLII_03294 7.5e-09
IKDGHLII_03295 7.8e-10 yocL
IKDGHLII_03296 2.5e-54 dksA T general stress protein
IKDGHLII_03298 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IKDGHLII_03299 0.0 recQ 3.6.4.12 L DNA helicase
IKDGHLII_03300 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
IKDGHLII_03302 2.4e-186 yocD 3.4.17.13 V peptidase S66
IKDGHLII_03303 1.6e-93 yocC
IKDGHLII_03304 8.9e-139 yocB J Protein required for attachment to host cells
IKDGHLII_03305 3.6e-91 yozB S membrane
IKDGHLII_03306 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IKDGHLII_03307 8.4e-54 czrA K transcriptional
IKDGHLII_03308 1.2e-91 yobW
IKDGHLII_03309 3.6e-134 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
IKDGHLII_03310 1.2e-92 yobS K Transcriptional regulator
IKDGHLII_03311 1.6e-131 yobQ K helix_turn_helix, arabinose operon control protein
IKDGHLII_03312 3.2e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
IKDGHLII_03313 1.7e-60 ykvN K Transcriptional regulator
IKDGHLII_03314 1.9e-130 IQ Enoyl-(Acyl carrier protein) reductase
IKDGHLII_03315 1.5e-43
IKDGHLII_03316 6.9e-96 hpr K helix_turn_helix multiple antibiotic resistance protein
IKDGHLII_03319 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IKDGHLII_03320 2.8e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IKDGHLII_03321 1.7e-268 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
IKDGHLII_03322 7.4e-204 yoaB EGP Major facilitator Superfamily
IKDGHLII_03323 3.2e-133 yoxB
IKDGHLII_03324 8.3e-40 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IKDGHLII_03325 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IKDGHLII_03326 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IKDGHLII_03327 6.3e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IKDGHLII_03328 6.2e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IKDGHLII_03329 2.9e-149 gltC K Transcriptional regulator
IKDGHLII_03330 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
IKDGHLII_03331 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IKDGHLII_03332 2.1e-182 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IKDGHLII_03333 1.1e-153 gltR1 K Transcriptional regulator
IKDGHLII_03334 1.5e-14 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IKDGHLII_03335 1.8e-50 ybzH K Helix-turn-helix domain
IKDGHLII_03336 5.2e-199 ybcL EGP Major facilitator Superfamily
IKDGHLII_03337 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IKDGHLII_03338 1.8e-34 yoeD G Helix-turn-helix domain
IKDGHLII_03339 3.5e-97 L Integrase
IKDGHLII_03341 2.9e-96 yoeB S IseA DL-endopeptidase inhibitor
IKDGHLII_03342 8.7e-246 yoeA V MATE efflux family protein
IKDGHLII_03343 5.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
IKDGHLII_03344 3.3e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
IKDGHLII_03345 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_03346 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_03347 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_03348 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_03349 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
IKDGHLII_03350 1.2e-64 yngL S Protein of unknown function (DUF1360)
IKDGHLII_03351 3.6e-301 yngK T Glycosyl hydrolase-like 10
IKDGHLII_03352 1.8e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
IKDGHLII_03353 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IKDGHLII_03354 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
IKDGHLII_03355 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
IKDGHLII_03356 6.8e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
IKDGHLII_03357 1.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IKDGHLII_03358 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IKDGHLII_03359 3.2e-104 yngC S SNARE associated Golgi protein
IKDGHLII_03360 8.9e-159 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IKDGHLII_03361 9.6e-68 yngA S membrane
IKDGHLII_03362 6.9e-144 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IKDGHLII_03363 3.3e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IKDGHLII_03364 1.5e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IKDGHLII_03365 9.2e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IKDGHLII_03366 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IKDGHLII_03367 5.6e-217 bioI 1.14.14.46 C Cytochrome P450
IKDGHLII_03368 1.2e-250 yxjC EG COG2610 H gluconate symporter and related permeases
IKDGHLII_03369 9.9e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IKDGHLII_03370 1.9e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IKDGHLII_03371 2.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IKDGHLII_03372 4.3e-217 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IKDGHLII_03373 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_03374 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_03375 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IKDGHLII_03376 4.7e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
IKDGHLII_03377 7e-250 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
IKDGHLII_03378 4.6e-126 T Transcriptional regulatory protein, C terminal
IKDGHLII_03379 2.3e-230 T PhoQ Sensor
IKDGHLII_03380 1.2e-49 S Domain of unknown function (DUF4870)
IKDGHLII_03381 6.7e-284 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
IKDGHLII_03382 3.7e-130 T intracellular signal transduction
IKDGHLII_03383 2.1e-97 S MTH538 TIR-like domain (DUF1863)
IKDGHLII_03384 4.1e-295 yndJ S YndJ-like protein
IKDGHLII_03385 9.5e-80 yndH S Domain of unknown function (DUF4166)
IKDGHLII_03386 5.4e-155 yndG S DoxX-like family
IKDGHLII_03387 1.5e-220 exuT G Sugar (and other) transporter
IKDGHLII_03388 5.1e-179 kdgR_1 K transcriptional
IKDGHLII_03389 2.2e-143 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IKDGHLII_03390 6e-210 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
IKDGHLII_03391 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
IKDGHLII_03392 8.5e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
IKDGHLII_03393 5.7e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
IKDGHLII_03394 5.2e-246 agcS E Sodium alanine symporter
IKDGHLII_03395 5.1e-41 ynfC
IKDGHLII_03396 6e-13
IKDGHLII_03397 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IKDGHLII_03398 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IKDGHLII_03399 1.5e-68 yccU S CoA-binding protein
IKDGHLII_03400 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IKDGHLII_03401 1.1e-49 yneR S Belongs to the HesB IscA family
IKDGHLII_03402 1.4e-52 yneQ
IKDGHLII_03403 8.3e-75 yneP S Thioesterase-like superfamily
IKDGHLII_03404 7.1e-18 tlp S Belongs to the Tlp family
IKDGHLII_03407 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IKDGHLII_03408 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IKDGHLII_03409 7.5e-15 sspO S Belongs to the SspO family
IKDGHLII_03410 2.3e-19 sspP S Belongs to the SspP family
IKDGHLII_03411 1.4e-62 hspX O Spore coat protein
IKDGHLII_03412 5.5e-74 yneK S Protein of unknown function (DUF2621)
IKDGHLII_03413 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
IKDGHLII_03414 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
IKDGHLII_03415 1.7e-125 ccdA O cytochrome c biogenesis protein
IKDGHLII_03416 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
IKDGHLII_03417 2.3e-28 yneF S UPF0154 protein
IKDGHLII_03418 1.4e-80 yneE S Sporulation inhibitor of replication protein sirA
IKDGHLII_03419 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IKDGHLII_03420 9.8e-33 ynzC S UPF0291 protein
IKDGHLII_03421 3.5e-112 yneB L resolvase
IKDGHLII_03422 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IKDGHLII_03423 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IKDGHLII_03424 2.1e-12 yoaW
IKDGHLII_03425 1.2e-71 yndM S Protein of unknown function (DUF2512)
IKDGHLII_03426 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
IKDGHLII_03427 9.1e-08
IKDGHLII_03428 9.4e-139 yndL S Replication protein
IKDGHLII_03429 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
IKDGHLII_03430 0.0 yobO M Pectate lyase superfamily protein
IKDGHLII_03432 1.6e-91 yvgO
IKDGHLII_03434 3.4e-117 AA10,CBM73 S Pfam:Chitin_bind_3
IKDGHLII_03435 3.3e-200 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IKDGHLII_03436 5.6e-115 ynaE S Domain of unknown function (DUF3885)
IKDGHLII_03437 1.6e-99 J Acetyltransferase (GNAT) domain
IKDGHLII_03438 1.7e-142 yoaP 3.1.3.18 K YoaP-like
IKDGHLII_03440 1.2e-183 adhP 1.1.1.1 C alcohol dehydrogenase
IKDGHLII_03441 4.5e-67 S DinB family
IKDGHLII_03442 4e-122 K WYL domain
IKDGHLII_03443 1.7e-15
IKDGHLII_03447 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
IKDGHLII_03448 8.7e-284 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
IKDGHLII_03450 1.2e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
IKDGHLII_03451 7.3e-206 xylR GK ROK family
IKDGHLII_03452 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
IKDGHLII_03453 4.9e-249 xynT G MFS/sugar transport protein
IKDGHLII_03454 4.3e-208 mrjp G Major royal jelly protein
IKDGHLII_03455 7.4e-25 T Histidine kinase
IKDGHLII_03456 1.2e-40 S Protein of unknown function (DUF2568)
IKDGHLII_03458 3.2e-11
IKDGHLII_03460 7e-94
IKDGHLII_03461 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
IKDGHLII_03462 4.3e-68 glnR K transcriptional
IKDGHLII_03463 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IKDGHLII_03464 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IKDGHLII_03465 1.3e-176 spoVK O stage V sporulation protein K
IKDGHLII_03466 2.4e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IKDGHLII_03467 3.8e-108 ymaB S MutT family
IKDGHLII_03468 1.4e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IKDGHLII_03469 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IKDGHLII_03470 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
IKDGHLII_03471 1.8e-20 ymzA
IKDGHLII_03472 1.8e-41
IKDGHLII_03473 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IKDGHLII_03474 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IKDGHLII_03475 3.3e-44 ymaF S YmaF family
IKDGHLII_03477 2.6e-47 ebrA P Small Multidrug Resistance protein
IKDGHLII_03478 2.6e-53 ebrB P Small Multidrug Resistance protein
IKDGHLII_03479 6e-79 ymaD O redox protein, regulator of disulfide bond formation
IKDGHLII_03480 3e-125 ymaC S Replication protein
IKDGHLII_03481 5.7e-255 aprX O Belongs to the peptidase S8 family
IKDGHLII_03482 4.1e-62 ymzB
IKDGHLII_03483 3.6e-118 yoaK S Membrane
IKDGHLII_03484 1.9e-77 nucB M Deoxyribonuclease NucA/NucB
IKDGHLII_03485 1.3e-229 cypA C Cytochrome P450
IKDGHLII_03486 0.0 pks13 HQ Beta-ketoacyl synthase
IKDGHLII_03487 0.0 dhbF IQ polyketide synthase
IKDGHLII_03488 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
IKDGHLII_03489 0.0 Q Polyketide synthase of type I
IKDGHLII_03490 0.0 rhiB IQ polyketide synthase
IKDGHLII_03491 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IKDGHLII_03492 3.5e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
IKDGHLII_03493 2.6e-241 pksG 2.3.3.10 I synthase
IKDGHLII_03494 5.5e-34 acpK IQ Phosphopantetheine attachment site
IKDGHLII_03495 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IKDGHLII_03496 1.1e-183 pksD Q Acyl transferase domain
IKDGHLII_03497 5.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IKDGHLII_03498 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
IKDGHLII_03500 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IKDGHLII_03501 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IKDGHLII_03502 1.7e-88 cotE S Spore coat protein
IKDGHLII_03503 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IKDGHLII_03504 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IKDGHLII_03505 2.6e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IKDGHLII_03506 9.6e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IKDGHLII_03507 1.2e-36 spoVS S Stage V sporulation protein S
IKDGHLII_03508 4.9e-153 ymdB S protein conserved in bacteria
IKDGHLII_03509 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
IKDGHLII_03510 1.1e-193 pbpX V Beta-lactamase
IKDGHLII_03511 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IKDGHLII_03512 7.1e-231 cinA 3.5.1.42 S Belongs to the CinA family
IKDGHLII_03513 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IKDGHLII_03514 2.5e-124 ymfM S protein conserved in bacteria
IKDGHLII_03515 1e-142 ymfK S Protein of unknown function (DUF3388)
IKDGHLII_03516 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
IKDGHLII_03517 6.6e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IKDGHLII_03518 6e-241 ymfH S zinc protease
IKDGHLII_03519 1.8e-237 ymfF S Peptidase M16
IKDGHLII_03520 0.0 ydgH S drug exporters of the RND superfamily
IKDGHLII_03521 8.2e-76 K helix_turn_helix multiple antibiotic resistance protein
IKDGHLII_03522 3e-227 ymfD EGP Major facilitator Superfamily
IKDGHLII_03523 4.4e-132 ymfC K Transcriptional regulator
IKDGHLII_03524 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IKDGHLII_03525 6.3e-31 S YlzJ-like protein
IKDGHLII_03526 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
IKDGHLII_03527 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IKDGHLII_03528 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IKDGHLII_03529 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IKDGHLII_03530 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IKDGHLII_03531 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IKDGHLII_03532 1e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
IKDGHLII_03533 2.6e-42 ymxH S YlmC YmxH family
IKDGHLII_03534 1.2e-233 pepR S Belongs to the peptidase M16 family
IKDGHLII_03535 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
IKDGHLII_03536 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IKDGHLII_03537 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IKDGHLII_03538 4.6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IKDGHLII_03539 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IKDGHLII_03540 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IKDGHLII_03541 3.9e-44 ylxP S protein conserved in bacteria
IKDGHLII_03542 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IKDGHLII_03543 1.8e-47 ylxQ J ribosomal protein
IKDGHLII_03544 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
IKDGHLII_03545 5.4e-206 nusA K Participates in both transcription termination and antitermination
IKDGHLII_03546 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
IKDGHLII_03547 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IKDGHLII_03548 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IKDGHLII_03549 5.9e-233 rasP M zinc metalloprotease
IKDGHLII_03550 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IKDGHLII_03551 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
IKDGHLII_03552 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IKDGHLII_03553 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IKDGHLII_03554 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IKDGHLII_03555 1.7e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IKDGHLII_03556 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
IKDGHLII_03557 8e-50 ylxL
IKDGHLII_03558 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKDGHLII_03559 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IKDGHLII_03560 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IKDGHLII_03561 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
IKDGHLII_03562 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
IKDGHLII_03563 2.5e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IKDGHLII_03564 7e-156 flhG D Belongs to the ParA family
IKDGHLII_03565 2.2e-191 flhF N Flagellar biosynthesis regulator FlhF
IKDGHLII_03566 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IKDGHLII_03567 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IKDGHLII_03568 5.2e-131 fliR N Flagellar biosynthetic protein FliR
IKDGHLII_03569 2e-37 fliQ N Role in flagellar biosynthesis
IKDGHLII_03570 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
IKDGHLII_03571 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
IKDGHLII_03572 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
IKDGHLII_03573 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IKDGHLII_03574 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IKDGHLII_03575 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
IKDGHLII_03576 5.7e-138 flgG N Flagellar basal body rod
IKDGHLII_03577 2.4e-72 flgD N Flagellar basal body rod modification protein
IKDGHLII_03578 8e-204 fliK N Flagellar hook-length control protein
IKDGHLII_03579 1.3e-47 ylxF S MgtE intracellular N domain
IKDGHLII_03580 2e-71 fliJ N Flagellar biosynthesis chaperone
IKDGHLII_03581 5.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IKDGHLII_03582 1.5e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
IKDGHLII_03583 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IKDGHLII_03584 1.4e-263 fliF N The M ring may be actively involved in energy transduction
IKDGHLII_03585 2.5e-31 fliE N Flagellar hook-basal body
IKDGHLII_03586 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
IKDGHLII_03587 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IKDGHLII_03588 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IKDGHLII_03589 1.4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IKDGHLII_03590 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IKDGHLII_03591 7.2e-172 xerC L tyrosine recombinase XerC
IKDGHLII_03592 2.4e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IKDGHLII_03593 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IKDGHLII_03594 2.6e-166 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
IKDGHLII_03595 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IKDGHLII_03596 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IKDGHLII_03597 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
IKDGHLII_03598 1.8e-301 ylqG
IKDGHLII_03599 2e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IKDGHLII_03600 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IKDGHLII_03601 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IKDGHLII_03602 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IKDGHLII_03603 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IKDGHLII_03604 1.3e-61 ylqD S YlqD protein
IKDGHLII_03605 1.7e-35 ylqC S Belongs to the UPF0109 family
IKDGHLII_03606 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IKDGHLII_03607 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IKDGHLII_03608 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IKDGHLII_03609 7.9e-140 S Phosphotransferase enzyme family
IKDGHLII_03610 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IKDGHLII_03611 0.0 smc D Required for chromosome condensation and partitioning
IKDGHLII_03612 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IKDGHLII_03613 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IKDGHLII_03614 4.6e-129 IQ reductase
IKDGHLII_03615 5.9e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IKDGHLII_03616 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IKDGHLII_03617 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IKDGHLII_03618 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IKDGHLII_03619 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
IKDGHLII_03620 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
IKDGHLII_03621 4.9e-304 yloV S kinase related to dihydroxyacetone kinase
IKDGHLII_03622 5.5e-59 asp S protein conserved in bacteria
IKDGHLII_03623 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IKDGHLII_03624 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
IKDGHLII_03625 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IKDGHLII_03626 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IKDGHLII_03627 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IKDGHLII_03628 2.3e-139 stp 3.1.3.16 T phosphatase
IKDGHLII_03629 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IKDGHLII_03630 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IKDGHLII_03631 1.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IKDGHLII_03632 1.5e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IKDGHLII_03633 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IKDGHLII_03634 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IKDGHLII_03635 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IKDGHLII_03636 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IKDGHLII_03637 1.5e-40 ylzA S Belongs to the UPF0296 family
IKDGHLII_03638 7.7e-155 yloC S stress-induced protein
IKDGHLII_03639 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
IKDGHLII_03640 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IKDGHLII_03641 2.7e-77 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
IKDGHLII_03642 3.2e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
IKDGHLII_03643 4.5e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IKDGHLII_03644 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
IKDGHLII_03645 2.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
IKDGHLII_03646 1.1e-176 cysP P phosphate transporter
IKDGHLII_03647 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
IKDGHLII_03649 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IKDGHLII_03650 1.4e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IKDGHLII_03651 1.1e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IKDGHLII_03652 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IKDGHLII_03653 0.0 carB 6.3.5.5 F Belongs to the CarB family
IKDGHLII_03654 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IKDGHLII_03655 1.2e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IKDGHLII_03656 2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IKDGHLII_03657 8.8e-232 pyrP F Xanthine uracil
IKDGHLII_03658 2.3e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IKDGHLII_03659 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IKDGHLII_03660 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IKDGHLII_03661 1.2e-61 dksA T COG1734 DnaK suppressor protein
IKDGHLII_03662 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IKDGHLII_03663 8.9e-68 divIVA D Cell division initiation protein
IKDGHLII_03664 6.1e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
IKDGHLII_03665 5.2e-41 yggT S membrane
IKDGHLII_03666 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IKDGHLII_03667 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IKDGHLII_03668 7.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
IKDGHLII_03669 2.2e-38 ylmC S sporulation protein
IKDGHLII_03670 2.2e-251 argE 3.5.1.16 E Acetylornithine deacetylase
IKDGHLII_03671 1.6e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IKDGHLII_03672 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKDGHLII_03673 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IKDGHLII_03674 1.9e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IKDGHLII_03675 0.0 bpr O COG1404 Subtilisin-like serine proteases
IKDGHLII_03676 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IKDGHLII_03677 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IKDGHLII_03678 4.8e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IKDGHLII_03679 6.9e-167 murB 1.3.1.98 M cell wall formation
IKDGHLII_03680 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IKDGHLII_03681 2.2e-185 spoVE D Belongs to the SEDS family
IKDGHLII_03682 2.2e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IKDGHLII_03683 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IKDGHLII_03684 2.6e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IKDGHLII_03685 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
IKDGHLII_03686 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IKDGHLII_03687 2.9e-52 ftsL D Essential cell division protein
IKDGHLII_03688 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IKDGHLII_03689 1.2e-77 mraZ K Belongs to the MraZ family
IKDGHLII_03690 6.3e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IKDGHLII_03691 7.2e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IKDGHLII_03692 2e-88 ylbP K n-acetyltransferase
IKDGHLII_03693 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IKDGHLII_03694 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IKDGHLII_03695 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
IKDGHLII_03696 2.1e-227 ylbM S Belongs to the UPF0348 family
IKDGHLII_03697 1.6e-188 ylbL T Belongs to the peptidase S16 family
IKDGHLII_03698 4.4e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
IKDGHLII_03699 6.3e-216 ylbJ S Sporulation integral membrane protein YlbJ
IKDGHLII_03700 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IKDGHLII_03701 6e-97 rsmD 2.1.1.171 L Methyltransferase
IKDGHLII_03703 5.5e-43 ylbG S UPF0298 protein
IKDGHLII_03704 1.2e-71 ylbF S Belongs to the UPF0342 family
IKDGHLII_03705 8.8e-37 ylbE S YlbE-like protein
IKDGHLII_03706 2.1e-54 ylbD S Putative coat protein
IKDGHLII_03707 2.3e-198 ylbC S protein with SCP PR1 domains
IKDGHLII_03708 2.2e-73 ylbB T COG0517 FOG CBS domain
IKDGHLII_03709 3.2e-59 ylbA S YugN-like family
IKDGHLII_03710 2e-163 ctaG S cytochrome c oxidase
IKDGHLII_03711 1.9e-50 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IKDGHLII_03712 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IKDGHLII_03713 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IKDGHLII_03714 1.2e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IKDGHLII_03715 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IKDGHLII_03716 5.9e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IKDGHLII_03717 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IKDGHLII_03718 3.2e-212 ftsW D Belongs to the SEDS family
IKDGHLII_03719 8.7e-44 ylaN S Belongs to the UPF0358 family
IKDGHLII_03720 1.3e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
IKDGHLII_03721 8.5e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IKDGHLII_03722 1.3e-243 phoH T ATPase related to phosphate starvation-inducible protein PhoH
IKDGHLII_03723 2.6e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IKDGHLII_03724 1.4e-33 ylaI S protein conserved in bacteria
IKDGHLII_03725 1.9e-47 ylaH S YlaH-like protein
IKDGHLII_03726 0.0 typA T GTP-binding protein TypA
IKDGHLII_03727 6.7e-24 S Family of unknown function (DUF5325)
IKDGHLII_03728 2.3e-36 ylaE
IKDGHLII_03729 8.1e-12 sigC S Putative zinc-finger
IKDGHLII_03730 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
IKDGHLII_03731 2.6e-82 ykzC S Acetyltransferase (GNAT) family
IKDGHLII_03732 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
IKDGHLII_03733 6.3e-24 ykzI
IKDGHLII_03734 1.8e-118 yktB S Belongs to the UPF0637 family
IKDGHLII_03735 3.5e-42 yktA S Belongs to the UPF0223 family
IKDGHLII_03736 9.5e-275 speA 4.1.1.19 E Arginine
IKDGHLII_03737 4.6e-135 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
IKDGHLII_03738 8.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
IKDGHLII_03739 1.2e-250 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IKDGHLII_03740 1.1e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IKDGHLII_03741 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IKDGHLII_03742 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IKDGHLII_03743 7.4e-208 V Beta-lactamase
IKDGHLII_03744 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
IKDGHLII_03745 0.0 Q Polyketide synthase of type I
IKDGHLII_03746 0.0 Q Polyketide synthase of type I
IKDGHLII_03747 0.0 Q Polyketide synthase of type I
IKDGHLII_03748 0.0 Q Polyketide synthase of type I
IKDGHLII_03749 0.0 Q polyketide synthase
IKDGHLII_03750 0.0 Q Polyketide synthase of type I
IKDGHLII_03751 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IKDGHLII_03752 1.6e-101 recN L Putative cell-wall binding lipoprotein
IKDGHLII_03754 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IKDGHLII_03755 7.4e-146 ykrA S hydrolases of the HAD superfamily
IKDGHLII_03756 8.2e-31 ykzG S Belongs to the UPF0356 family
IKDGHLII_03757 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IKDGHLII_03758 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IKDGHLII_03759 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
IKDGHLII_03760 1e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
IKDGHLII_03761 3.4e-244 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
IKDGHLII_03762 1.8e-44 abrB K of stationary sporulation gene expression
IKDGHLII_03763 6.9e-184 mreB D Rod-share determining protein MreBH
IKDGHLII_03764 5.5e-12 S Uncharacterized protein YkpC
IKDGHLII_03765 3.6e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IKDGHLII_03766 1.7e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IKDGHLII_03767 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IKDGHLII_03768 1.7e-36 ykoA
IKDGHLII_03769 3.3e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IKDGHLII_03770 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IKDGHLII_03771 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
IKDGHLII_03772 1.1e-130 fruR K Transcriptional regulator
IKDGHLII_03773 1.3e-205 yknZ V ABC transporter (permease)
IKDGHLII_03774 2e-121 macB V ABC transporter, ATP-binding protein
IKDGHLII_03775 2.3e-167 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IKDGHLII_03776 8.3e-104 yknW S Yip1 domain
IKDGHLII_03777 1.7e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IKDGHLII_03778 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
IKDGHLII_03779 1.4e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IKDGHLII_03780 1.4e-242 moeA 2.10.1.1 H molybdopterin
IKDGHLII_03781 3.2e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IKDGHLII_03782 4.1e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IKDGHLII_03783 6.8e-160 yknT
IKDGHLII_03784 4.5e-98 rok K Repressor of ComK
IKDGHLII_03785 7.4e-77 ykuV CO thiol-disulfide
IKDGHLII_03786 1.9e-139 ykuT M Mechanosensitive ion channel
IKDGHLII_03787 4.8e-38 ykuS S Belongs to the UPF0180 family
IKDGHLII_03788 9.9e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IKDGHLII_03789 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IKDGHLII_03790 6e-79 fld C Flavodoxin
IKDGHLII_03791 5.7e-166 ykuO
IKDGHLII_03792 1.3e-89 fld C Flavodoxin
IKDGHLII_03793 1.3e-167 ccpC K Transcriptional regulator
IKDGHLII_03794 1e-75 ykuL S CBS domain
IKDGHLII_03795 2.1e-25 ykzF S Antirepressor AbbA
IKDGHLII_03796 9.2e-92 ykuK S Ribonuclease H-like
IKDGHLII_03797 3.9e-37 ykuJ S protein conserved in bacteria
IKDGHLII_03798 3.7e-232 ykuI T Diguanylate phosphodiesterase
IKDGHLII_03800 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IKDGHLII_03801 1.4e-153 ykuE S Metallophosphoesterase
IKDGHLII_03802 4.1e-89 ykuD S protein conserved in bacteria
IKDGHLII_03803 5.6e-239 ykuC EGP Major facilitator Superfamily
IKDGHLII_03804 1.4e-83 ykyB S YkyB-like protein
IKDGHLII_03805 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
IKDGHLII_03806 2.3e-09
IKDGHLII_03807 4.3e-214 patA 2.6.1.1 E Aminotransferase
IKDGHLII_03808 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
IKDGHLII_03809 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
IKDGHLII_03810 1.6e-111 ykwD J protein with SCP PR1 domains
IKDGHLII_03811 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IKDGHLII_03812 7.2e-262 mcpC NT chemotaxis protein
IKDGHLII_03813 2.4e-192 splB 4.1.99.14 L Spore photoproduct lyase
IKDGHLII_03814 6.1e-38 splA S Transcriptional regulator
IKDGHLII_03815 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IKDGHLII_03816 2.1e-39 ptsH G phosphocarrier protein HPr
IKDGHLII_03817 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IKDGHLII_03818 5.1e-156 glcT K antiterminator
IKDGHLII_03819 3.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
IKDGHLII_03821 2.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IKDGHLII_03822 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IKDGHLII_03823 5e-87 stoA CO thiol-disulfide
IKDGHLII_03824 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IKDGHLII_03825 5.3e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
IKDGHLII_03826 3.9e-27
IKDGHLII_03827 7.8e-25 ykvS S protein conserved in bacteria
IKDGHLII_03828 3.5e-45 ykvR S Protein of unknown function (DUF3219)
IKDGHLII_03829 1.1e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IKDGHLII_03830 1.8e-151 L Belongs to the 'phage' integrase family
IKDGHLII_03831 8.6e-97 K Helix-turn-helix domain
IKDGHLII_03832 7.6e-13 K Transcriptional regulator
IKDGHLII_03833 9.9e-15
IKDGHLII_03834 1.5e-13 S YolD-like protein
IKDGHLII_03836 2.8e-33 S Bacteriophage A118-like holin, Hol118
IKDGHLII_03837 9.6e-148 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
IKDGHLII_03838 4.5e-29 S BhlA holin family
IKDGHLII_03840 9.9e-13
IKDGHLII_03841 1.9e-87
IKDGHLII_03842 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
IKDGHLII_03843 1.4e-78 L Prophage endopeptidase tail
IKDGHLII_03844 1.4e-60 S Phage tail protein
IKDGHLII_03845 5.9e-111 D phage tail tape measure protein
IKDGHLII_03846 2.2e-41 V Restriction endonuclease
IKDGHLII_03847 5.1e-41 D phage tail tape measure protein
IKDGHLII_03849 1e-23
IKDGHLII_03850 8.8e-48 eae N domain, Protein
IKDGHLII_03851 2.4e-20
IKDGHLII_03852 3.6e-30
IKDGHLII_03853 4.6e-17
IKDGHLII_03854 1.6e-27
IKDGHLII_03856 3.3e-147 S Family of unknown function (DUF5309)
IKDGHLII_03857 2.5e-20
IKDGHLII_03858 1.9e-78 S Phage minor capsid protein 2
IKDGHLII_03859 8.8e-165
IKDGHLII_03860 5.4e-29 S Helix-turn-helix of insertion element transposase
IKDGHLII_03861 4.4e-255 S TIGRFAM Phage
IKDGHLII_03862 2.9e-67 L Phage integrase family
IKDGHLII_03864 6.3e-18
IKDGHLII_03866 8.8e-10 K Cro/C1-type HTH DNA-binding domain
IKDGHLII_03870 2.2e-46
IKDGHLII_03871 9.2e-23
IKDGHLII_03873 2.8e-119 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
IKDGHLII_03875 3.6e-135
IKDGHLII_03876 7.7e-48
IKDGHLII_03877 3.6e-48 K Sigma-70, region 4
IKDGHLII_03878 2e-142 L the current gene model (or a revised gene model) may contain a
IKDGHLII_03880 1e-138 S C-5 cytosine-specific DNA methylase
IKDGHLII_03881 1.3e-62 2.7.1.24 H dephospho-CoA kinase activity
IKDGHLII_03883 4.3e-58
IKDGHLII_03885 6e-65 S SprT-like family
IKDGHLII_03886 1e-35 S protein conserved in bacteria
IKDGHLII_03887 1.9e-90 thyX 2.1.1.148 H Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
IKDGHLII_03888 7.1e-14
IKDGHLII_03890 2.5e-59 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
IKDGHLII_03892 5.9e-148 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IKDGHLII_03894 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IKDGHLII_03895 3.2e-43 nrdI 1.17.4.1 F Belongs to the NrdI family
IKDGHLII_03899 5.8e-16 S Protein of unknown function (DUF1523)
IKDGHLII_03902 8.5e-32 3.1.22.4 S Crossover junction endodeoxyribonuclease RuvC
IKDGHLII_03904 2.9e-164
IKDGHLII_03905 7.1e-103 2.7.7.7 L EXOIII
IKDGHLII_03906 1.1e-202 L 3'-5' exonuclease
IKDGHLII_03908 8.1e-41
IKDGHLII_03909 1.1e-32
IKDGHLII_03910 3.7e-39
IKDGHLII_03914 4.2e-50
IKDGHLII_03915 1.7e-07 S Cro/C1-type HTH DNA-binding domain
IKDGHLII_03916 3.9e-08 K Cro/C1-type HTH DNA-binding domain
IKDGHLII_03917 1e-131 dnaG L Toprim-like
IKDGHLII_03918 2.5e-144 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
IKDGHLII_03920 2.9e-08 yodN
IKDGHLII_03922 3.3e-88 L DNA-dependent DNA replication
IKDGHLII_03924 5.3e-37
IKDGHLII_03925 7e-19
IKDGHLII_03927 4.2e-15
IKDGHLII_03930 2.9e-35
IKDGHLII_03933 1.1e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IKDGHLII_03934 1.8e-151 L Belongs to the 'phage' integrase family
IKDGHLII_03935 8.6e-97 K Helix-turn-helix domain
IKDGHLII_03936 7.6e-13 K Transcriptional regulator
IKDGHLII_03937 9.9e-15
IKDGHLII_03938 1.5e-13 S YolD-like protein
IKDGHLII_03940 2.8e-33 S Bacteriophage A118-like holin, Hol118
IKDGHLII_03941 9.6e-148 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
IKDGHLII_03942 4.5e-29 S BhlA holin family
IKDGHLII_03944 9.9e-13
IKDGHLII_03945 1.9e-87
IKDGHLII_03946 1.5e-48 S Peptidase_G2, IMC autoproteolytic cleavage domain
IKDGHLII_03947 1.3e-286 S Peptidase_G2, IMC autoproteolytic cleavage domain
IKDGHLII_03948 4.2e-37 L Prophage endopeptidase tail
IKDGHLII_03949 3.3e-15 L Prophage endopeptidase tail
IKDGHLII_03950 1.5e-60 NU Prophage endopeptidase tail
IKDGHLII_03951 1.5e-18 D phage tail tape measure protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)