ORF_ID e_value Gene_name EC_number CAZy COGs Description
HKLHMJLG_00001 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKLHMJLG_00002 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKLHMJLG_00003 2.4e-33 yaaA S S4 domain
HKLHMJLG_00004 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKLHMJLG_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
HKLHMJLG_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKLHMJLG_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKLHMJLG_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
HKLHMJLG_00011 1.5e-183 yaaC S YaaC-like Protein
HKLHMJLG_00012 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKLHMJLG_00013 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKLHMJLG_00014 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HKLHMJLG_00015 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HKLHMJLG_00016 2.8e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKLHMJLG_00017 2.9e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HKLHMJLG_00018 1.3e-09
HKLHMJLG_00019 2e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HKLHMJLG_00020 4.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HKLHMJLG_00021 5.8e-212 yaaH M Glycoside Hydrolase Family
HKLHMJLG_00022 2e-100 yaaI Q COG1335 Amidases related to nicotinamidase
HKLHMJLG_00023 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKLHMJLG_00024 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKLHMJLG_00025 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKLHMJLG_00026 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKLHMJLG_00027 3.6e-32 yaaL S Protein of unknown function (DUF2508)
HKLHMJLG_00028 9.6e-37 bofA S Sigma-K factor-processing regulatory protein BofA
HKLHMJLG_00029 3.4e-39 S COG NOG14552 non supervised orthologous group
HKLHMJLG_00032 2.2e-30 csfB S Inhibitor of sigma-G Gin
HKLHMJLG_00033 2.3e-97 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HKLHMJLG_00034 5.8e-192 yaaN P Belongs to the TelA family
HKLHMJLG_00035 8.9e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HKLHMJLG_00036 1.3e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKLHMJLG_00037 7.5e-55 yaaQ S protein conserved in bacteria
HKLHMJLG_00038 1.2e-71 yaaR S protein conserved in bacteria
HKLHMJLG_00039 1.3e-182 holB 2.7.7.7 L DNA polymerase III
HKLHMJLG_00040 8.8e-145 yaaT S stage 0 sporulation protein
HKLHMJLG_00041 7.7e-37 yabA L Involved in initiation control of chromosome replication
HKLHMJLG_00042 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HKLHMJLG_00043 4.7e-48 yazA L endonuclease containing a URI domain
HKLHMJLG_00044 3.8e-162 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKLHMJLG_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HKLHMJLG_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKLHMJLG_00047 2.2e-142 tatD L hydrolase, TatD
HKLHMJLG_00048 1.8e-232 rpfB GH23 T protein conserved in bacteria
HKLHMJLG_00049 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKLHMJLG_00050 1.1e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKLHMJLG_00051 1.9e-145 yabG S peptidase
HKLHMJLG_00052 7.8e-39 veg S protein conserved in bacteria
HKLHMJLG_00053 2.9e-27 sspF S DNA topological change
HKLHMJLG_00054 7.8e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKLHMJLG_00055 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HKLHMJLG_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HKLHMJLG_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HKLHMJLG_00058 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKLHMJLG_00059 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKLHMJLG_00060 2e-106 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HKLHMJLG_00061 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKLHMJLG_00062 3.7e-40 yabK S Peptide ABC transporter permease
HKLHMJLG_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKLHMJLG_00064 6.2e-91 spoVT K stage V sporulation protein
HKLHMJLG_00065 1.6e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKLHMJLG_00066 2.7e-277 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HKLHMJLG_00067 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HKLHMJLG_00068 1.9e-49 yabP S Sporulation protein YabP
HKLHMJLG_00069 2.9e-103 yabQ S spore cortex biosynthesis protein
HKLHMJLG_00070 4.1e-57 divIC D Septum formation initiator
HKLHMJLG_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HKLHMJLG_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HKLHMJLG_00075 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
HKLHMJLG_00076 6.2e-185 KLT serine threonine protein kinase
HKLHMJLG_00077 7.7e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKLHMJLG_00078 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKLHMJLG_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKLHMJLG_00080 6.3e-145 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKLHMJLG_00081 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKLHMJLG_00082 1.1e-156 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HKLHMJLG_00083 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKLHMJLG_00084 1.4e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKLHMJLG_00085 1.4e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HKLHMJLG_00086 3.2e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HKLHMJLG_00087 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKLHMJLG_00088 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKLHMJLG_00089 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKLHMJLG_00090 4.5e-29 yazB K transcriptional
HKLHMJLG_00091 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKLHMJLG_00092 6.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HKLHMJLG_00093 3.4e-39 S COG NOG14552 non supervised orthologous group
HKLHMJLG_00095 1.3e-07
HKLHMJLG_00098 2e-08
HKLHMJLG_00103 3.4e-39 S COG NOG14552 non supervised orthologous group
HKLHMJLG_00104 7.5e-77 ctsR K Belongs to the CtsR family
HKLHMJLG_00105 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HKLHMJLG_00106 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HKLHMJLG_00107 0.0 clpC O Belongs to the ClpA ClpB family
HKLHMJLG_00108 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKLHMJLG_00109 2.9e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HKLHMJLG_00110 2.7e-194 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HKLHMJLG_00111 9.4e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HKLHMJLG_00112 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKLHMJLG_00113 8.1e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKLHMJLG_00114 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
HKLHMJLG_00115 6.2e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKLHMJLG_00116 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKLHMJLG_00117 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKLHMJLG_00118 4.2e-89 yacP S RNA-binding protein containing a PIN domain
HKLHMJLG_00119 8.9e-116 sigH K Belongs to the sigma-70 factor family
HKLHMJLG_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKLHMJLG_00121 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HKLHMJLG_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKLHMJLG_00123 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKLHMJLG_00124 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKLHMJLG_00125 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKLHMJLG_00126 1.4e-107 rsmC 2.1.1.172 J Methyltransferase
HKLHMJLG_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLHMJLG_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLHMJLG_00129 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HKLHMJLG_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKLHMJLG_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKLHMJLG_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKLHMJLG_00133 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKLHMJLG_00134 2.9e-187 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HKLHMJLG_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HKLHMJLG_00136 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKLHMJLG_00137 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HKLHMJLG_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKLHMJLG_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKLHMJLG_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKLHMJLG_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKLHMJLG_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKLHMJLG_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKLHMJLG_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HKLHMJLG_00145 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKLHMJLG_00146 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKLHMJLG_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKLHMJLG_00148 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKLHMJLG_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKLHMJLG_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKLHMJLG_00151 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKLHMJLG_00152 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKLHMJLG_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKLHMJLG_00154 1.9e-23 rpmD J Ribosomal protein L30
HKLHMJLG_00155 1.1e-72 rplO J binds to the 23S rRNA
HKLHMJLG_00156 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKLHMJLG_00157 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKLHMJLG_00158 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
HKLHMJLG_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKLHMJLG_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HKLHMJLG_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKLHMJLG_00162 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKLHMJLG_00163 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLHMJLG_00164 4.7e-58 rplQ J Ribosomal protein L17
HKLHMJLG_00165 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLHMJLG_00166 2.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLHMJLG_00167 3.8e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLHMJLG_00168 4.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKLHMJLG_00169 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKLHMJLG_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HKLHMJLG_00171 6.9e-144 ybaJ Q Methyltransferase domain
HKLHMJLG_00172 7.9e-82 yizA S Damage-inducible protein DinB
HKLHMJLG_00173 4.5e-79 ybaK S Protein of unknown function (DUF2521)
HKLHMJLG_00174 1.3e-133 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKLHMJLG_00175 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HKLHMJLG_00176 7.6e-76 gerD
HKLHMJLG_00177 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HKLHMJLG_00178 1.4e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
HKLHMJLG_00179 3.4e-39 S COG NOG14552 non supervised orthologous group
HKLHMJLG_00182 1.6e-08
HKLHMJLG_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
HKLHMJLG_00186 4.6e-219 glcP G Major Facilitator Superfamily
HKLHMJLG_00187 2.1e-246 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKLHMJLG_00188 9.7e-180 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HKLHMJLG_00189 4.4e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HKLHMJLG_00190 7.1e-227 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HKLHMJLG_00191 9.7e-175 ybaS 1.1.1.58 S Na -dependent transporter
HKLHMJLG_00192 3.3e-114 ybbA S Putative esterase
HKLHMJLG_00193 8e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMJLG_00194 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMJLG_00195 5.7e-172 feuA P Iron-uptake system-binding protein
HKLHMJLG_00196 0.0 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HKLHMJLG_00197 1.2e-238 ybbC 3.2.1.52 S protein conserved in bacteria
HKLHMJLG_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HKLHMJLG_00199 2.8e-246 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HKLHMJLG_00200 4.4e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKLHMJLG_00201 9.5e-164 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKLHMJLG_00202 1.1e-86 ybbJ J acetyltransferase
HKLHMJLG_00203 8.7e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HKLHMJLG_00209 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HKLHMJLG_00210 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HKLHMJLG_00211 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKLHMJLG_00212 2.6e-224 ybbR S protein conserved in bacteria
HKLHMJLG_00213 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKLHMJLG_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKLHMJLG_00215 2.5e-72 L Psort location Cytoplasmic, score
HKLHMJLG_00216 1.7e-43 S Protein of unknown function (DUF4435)
HKLHMJLG_00217 1.3e-101 ybdN
HKLHMJLG_00218 2.9e-133 ybdO S Domain of unknown function (DUF4885)
HKLHMJLG_00219 1.1e-163 dkgB S Aldo/keto reductase family
HKLHMJLG_00220 1e-93 yxaC M effector of murein hydrolase
HKLHMJLG_00221 5.3e-52 S LrgA family
HKLHMJLG_00222 4e-72 yxaD K helix_turn_helix multiple antibiotic resistance protein
HKLHMJLG_00224 6.8e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HKLHMJLG_00225 6.1e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HKLHMJLG_00226 6.3e-202 T COG4585 Signal transduction histidine kinase
HKLHMJLG_00227 1.9e-110 KT LuxR family transcriptional regulator
HKLHMJLG_00228 2.2e-168 V COG1131 ABC-type multidrug transport system, ATPase component
HKLHMJLG_00229 6.2e-208 V COG0842 ABC-type multidrug transport system, permease component
HKLHMJLG_00230 2.9e-199 V ABC-2 family transporter protein
HKLHMJLG_00231 2.2e-24
HKLHMJLG_00232 4.5e-77 S Domain of unknown function (DUF4879)
HKLHMJLG_00233 1.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HKLHMJLG_00234 2.9e-109 yqeB
HKLHMJLG_00235 9.2e-40 ybyB
HKLHMJLG_00236 2.5e-292 ybeC E amino acid
HKLHMJLG_00238 5.5e-45 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKLHMJLG_00239 5e-56
HKLHMJLG_00240 4e-16 S Protein of unknown function (DUF2651)
HKLHMJLG_00241 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKLHMJLG_00242 1.7e-259 glpT G -transporter
HKLHMJLG_00243 1.3e-16 S Protein of unknown function (DUF2651)
HKLHMJLG_00244 5e-212 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HKLHMJLG_00246 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HKLHMJLG_00247 4.6e-31
HKLHMJLG_00248 1.2e-82 K Helix-turn-helix XRE-family like proteins
HKLHMJLG_00249 1.5e-200 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HKLHMJLG_00250 1.1e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKLHMJLG_00251 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKLHMJLG_00252 1.9e-86 ybfM S SNARE associated Golgi protein
HKLHMJLG_00253 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HKLHMJLG_00254 1.2e-42 ybfN
HKLHMJLG_00255 2.3e-192 yceA S Belongs to the UPF0176 family
HKLHMJLG_00256 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKLHMJLG_00257 8.6e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HKLHMJLG_00258 4.1e-257 mmuP E amino acid
HKLHMJLG_00259 7.4e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HKLHMJLG_00260 3e-257 agcS E Sodium alanine symporter
HKLHMJLG_00261 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
HKLHMJLG_00262 1.5e-212 phoQ 2.7.13.3 T Histidine kinase
HKLHMJLG_00263 2.5e-172 glnL T Regulator
HKLHMJLG_00264 4.4e-36 ycbJ S Macrolide 2'-phosphotransferase
HKLHMJLG_00265 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HKLHMJLG_00266 1.8e-156 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKLHMJLG_00267 9.6e-112 ydfN C nitroreductase
HKLHMJLG_00268 4.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HKLHMJLG_00269 1.5e-62 mhqP S DoxX
HKLHMJLG_00270 7e-56 traF CO Thioredoxin
HKLHMJLG_00271 5.6e-62 ycbP S Protein of unknown function (DUF2512)
HKLHMJLG_00272 5.3e-77 sleB 3.5.1.28 M Cell wall
HKLHMJLG_00273 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HKLHMJLG_00274 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKLHMJLG_00275 4.7e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKLHMJLG_00276 1.1e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKLHMJLG_00277 3.1e-209 ycbU E Selenocysteine lyase
HKLHMJLG_00278 2.4e-238 lmrB EGP the major facilitator superfamily
HKLHMJLG_00279 1.2e-100 yxaF K Transcriptional regulator
HKLHMJLG_00280 1.2e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HKLHMJLG_00281 3.4e-112 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HKLHMJLG_00282 1.3e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
HKLHMJLG_00283 8.6e-173 yccK C Aldo keto reductase
HKLHMJLG_00284 1.6e-177 ycdA S Domain of unknown function (DUF5105)
HKLHMJLG_00285 3e-270 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HKLHMJLG_00286 8.2e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HKLHMJLG_00287 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
HKLHMJLG_00288 4.6e-189 S response regulator aspartate phosphatase
HKLHMJLG_00289 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HKLHMJLG_00290 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HKLHMJLG_00291 1.9e-49 S Domain of unknown function (DUF4188)
HKLHMJLG_00292 2.1e-46 padR K Virulence activator alpha C-term
HKLHMJLG_00293 2.3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
HKLHMJLG_00294 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HKLHMJLG_00295 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HKLHMJLG_00296 4.7e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKLHMJLG_00297 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HKLHMJLG_00298 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
HKLHMJLG_00299 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
HKLHMJLG_00300 9.7e-138 terC P Protein of unknown function (DUF475)
HKLHMJLG_00301 0.0 yceG S Putative component of 'biosynthetic module'
HKLHMJLG_00302 2.3e-193 yceH P Belongs to the TelA family
HKLHMJLG_00303 2.4e-215 naiP P Uncharacterised MFS-type transporter YbfB
HKLHMJLG_00304 4.3e-228 proV 3.6.3.32 E glycine betaine
HKLHMJLG_00305 1.6e-138 opuAB P glycine betaine
HKLHMJLG_00306 2e-163 opuAC E glycine betaine
HKLHMJLG_00307 2.5e-211 amhX S amidohydrolase
HKLHMJLG_00308 2e-229 ycgA S Membrane
HKLHMJLG_00309 2.2e-82 ycgB
HKLHMJLG_00310 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HKLHMJLG_00311 1.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKLHMJLG_00312 2.8e-261 mdr EGP Major facilitator Superfamily
HKLHMJLG_00313 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
HKLHMJLG_00314 1e-113 ycgF E Lysine exporter protein LysE YggA
HKLHMJLG_00315 7.6e-151 yqcI S YqcI/YcgG family
HKLHMJLG_00316 9.8e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HKLHMJLG_00317 7.6e-114 ycgI S Domain of unknown function (DUF1989)
HKLHMJLG_00318 6.9e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKLHMJLG_00319 8.9e-133 L Molecular Function DNA binding, Biological Process DNA recombination
HKLHMJLG_00320 1.1e-53 L COG2963 Transposase and inactivated derivatives
HKLHMJLG_00322 5.6e-109 tmrB S AAA domain
HKLHMJLG_00323 1.5e-149 4.2.1.118 G Xylose isomerase-like TIM barrel
HKLHMJLG_00324 4e-232 G COG0477 Permeases of the major facilitator superfamily
HKLHMJLG_00325 2.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKLHMJLG_00326 2.2e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HKLHMJLG_00327 3.6e-148 ycgL S Predicted nucleotidyltransferase
HKLHMJLG_00328 2.3e-170 ycgM E Proline dehydrogenase
HKLHMJLG_00329 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HKLHMJLG_00330 6.4e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKLHMJLG_00331 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HKLHMJLG_00332 3.8e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HKLHMJLG_00333 1.5e-280 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HKLHMJLG_00334 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
HKLHMJLG_00335 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HKLHMJLG_00336 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKLHMJLG_00337 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HKLHMJLG_00338 2.4e-223 nasA P COG2223 Nitrate nitrite transporter
HKLHMJLG_00339 4.2e-228 yciC S GTPases (G3E family)
HKLHMJLG_00340 5.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HKLHMJLG_00341 1.2e-73 yckC S membrane
HKLHMJLG_00342 4.2e-50 S Protein of unknown function (DUF2680)
HKLHMJLG_00343 1.2e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLHMJLG_00344 2.1e-67 nin S Competence protein J (ComJ)
HKLHMJLG_00345 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
HKLHMJLG_00346 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HKLHMJLG_00347 5.6e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HKLHMJLG_00348 6.3e-63 hxlR K transcriptional
HKLHMJLG_00349 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_00350 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_00351 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HKLHMJLG_00352 1.5e-140 srfAD Q thioesterase
HKLHMJLG_00353 7.2e-250 bamJ E Aminotransferase class I and II
HKLHMJLG_00354 4.8e-64 S YcxB-like protein
HKLHMJLG_00356 6e-169 ycxC EG EamA-like transporter family
HKLHMJLG_00357 1.3e-246 ycxD K GntR family transcriptional regulator
HKLHMJLG_00358 2.2e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HKLHMJLG_00359 2.8e-111 yczE S membrane
HKLHMJLG_00360 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKLHMJLG_00361 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
HKLHMJLG_00362 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HKLHMJLG_00363 2.5e-158 bsdA K LysR substrate binding domain
HKLHMJLG_00364 2.1e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKLHMJLG_00365 4.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HKLHMJLG_00366 2e-38 bsdD 4.1.1.61 S response to toxic substance
HKLHMJLG_00367 2.8e-37 yclD
HKLHMJLG_00368 5.9e-28 yclD
HKLHMJLG_00369 1.6e-269 dtpT E amino acid peptide transporter
HKLHMJLG_00370 1.9e-282 yclG M Pectate lyase superfamily protein
HKLHMJLG_00372 8.3e-296 gerKA EG Spore germination protein
HKLHMJLG_00373 2.9e-237 gerKC S spore germination
HKLHMJLG_00374 5.1e-196 gerKB F Spore germination protein
HKLHMJLG_00375 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKLHMJLG_00376 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKLHMJLG_00377 2.7e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
HKLHMJLG_00378 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
HKLHMJLG_00379 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HKLHMJLG_00380 6.8e-220 yxeP 3.5.1.47 E hydrolase activity
HKLHMJLG_00381 7.9e-252 yxeQ S MmgE/PrpD family
HKLHMJLG_00382 2.3e-122 yclH P ABC transporter
HKLHMJLG_00383 6.9e-238 yclI V ABC transporter (permease) YclI
HKLHMJLG_00384 5.2e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_00385 2.6e-261 T PhoQ Sensor
HKLHMJLG_00386 1.9e-81 S aspartate phosphatase
HKLHMJLG_00389 6.5e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
HKLHMJLG_00390 3e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMJLG_00391 1e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMJLG_00392 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HKLHMJLG_00393 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HKLHMJLG_00394 1e-249 ycnB EGP Major facilitator Superfamily
HKLHMJLG_00395 5.4e-153 ycnC K Transcriptional regulator
HKLHMJLG_00396 2.3e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
HKLHMJLG_00397 1e-44 ycnE S Monooxygenase
HKLHMJLG_00398 1.1e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHMJLG_00399 4.7e-263 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKLHMJLG_00400 1.5e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKLHMJLG_00401 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKLHMJLG_00402 3.6e-149 glcU U Glucose uptake
HKLHMJLG_00403 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKLHMJLG_00404 3.5e-98 ycnI S protein conserved in bacteria
HKLHMJLG_00405 3e-298 ycnJ P protein, homolog of Cu resistance protein CopC
HKLHMJLG_00406 5.6e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HKLHMJLG_00407 1.6e-55
HKLHMJLG_00408 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HKLHMJLG_00409 5.2e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HKLHMJLG_00410 2.6e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HKLHMJLG_00411 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HKLHMJLG_00413 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HKLHMJLG_00414 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
HKLHMJLG_00415 4.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HKLHMJLG_00416 3e-150 ycsI S Belongs to the D-glutamate cyclase family
HKLHMJLG_00417 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HKLHMJLG_00418 1.6e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HKLHMJLG_00419 4e-131 kipR K Transcriptional regulator
HKLHMJLG_00420 9.3e-118 ycsK E anatomical structure formation involved in morphogenesis
HKLHMJLG_00422 5.1e-56 yczJ S biosynthesis
HKLHMJLG_00423 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HKLHMJLG_00424 7.5e-174 ydhF S Oxidoreductase
HKLHMJLG_00425 0.0 mtlR K transcriptional regulator, MtlR
HKLHMJLG_00426 1.3e-287 ydaB IQ acyl-CoA ligase
HKLHMJLG_00427 3.7e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKLHMJLG_00428 4.6e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HKLHMJLG_00429 2.5e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKLHMJLG_00430 1.4e-77 ydaG 1.4.3.5 S general stress protein
HKLHMJLG_00431 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HKLHMJLG_00432 1.1e-53 L COG2963 Transposase and inactivated derivatives
HKLHMJLG_00433 8.9e-133 L Molecular Function DNA binding, Biological Process DNA recombination
HKLHMJLG_00434 1.3e-47 ydzA EGP Major facilitator Superfamily
HKLHMJLG_00435 1.5e-74 lrpC K Transcriptional regulator
HKLHMJLG_00436 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKLHMJLG_00437 1.3e-201 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HKLHMJLG_00438 2.7e-149 ydaK T Diguanylate cyclase, GGDEF domain
HKLHMJLG_00439 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HKLHMJLG_00440 5.5e-231 ydaM M Glycosyl transferase family group 2
HKLHMJLG_00441 0.0 ydaN S Bacterial cellulose synthase subunit
HKLHMJLG_00442 0.0 ydaO E amino acid
HKLHMJLG_00443 2.3e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HKLHMJLG_00444 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKLHMJLG_00445 4.7e-11
HKLHMJLG_00447 7.4e-79
HKLHMJLG_00448 3.5e-100
HKLHMJLG_00449 2.1e-39
HKLHMJLG_00450 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
HKLHMJLG_00452 6.5e-34 ydaT
HKLHMJLG_00453 1.1e-71 yvaD S Family of unknown function (DUF5360)
HKLHMJLG_00454 4.1e-54 yvaE P Small Multidrug Resistance protein
HKLHMJLG_00455 1.5e-141 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HKLHMJLG_00457 8.2e-63 ydbB G Cupin domain
HKLHMJLG_00458 1.3e-60 ydbC S Domain of unknown function (DUF4937
HKLHMJLG_00459 9.3e-155 ydbD P Catalase
HKLHMJLG_00460 2.2e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HKLHMJLG_00461 5.5e-300 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKLHMJLG_00462 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HKLHMJLG_00463 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKLHMJLG_00464 2.1e-159 ydbI S AI-2E family transporter
HKLHMJLG_00465 5e-173 ydbJ V ABC transporter, ATP-binding protein
HKLHMJLG_00466 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKLHMJLG_00467 2.1e-52 ydbL
HKLHMJLG_00468 2.2e-207 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HKLHMJLG_00469 1.5e-10 S Fur-regulated basic protein B
HKLHMJLG_00470 5.8e-09 S Fur-regulated basic protein A
HKLHMJLG_00471 8.1e-120 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKLHMJLG_00472 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKLHMJLG_00473 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HKLHMJLG_00474 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKLHMJLG_00475 1.3e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKLHMJLG_00476 1.3e-60 ydbS S Bacterial PH domain
HKLHMJLG_00477 7.5e-264 ydbT S Membrane
HKLHMJLG_00478 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HKLHMJLG_00479 1.1e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKLHMJLG_00480 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HKLHMJLG_00481 2.2e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKLHMJLG_00482 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HKLHMJLG_00483 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HKLHMJLG_00484 5.7e-144 rsbR T Positive regulator of sigma-B
HKLHMJLG_00485 1.8e-57 rsbS T antagonist
HKLHMJLG_00486 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HKLHMJLG_00487 2.5e-186 rsbU 3.1.3.3 KT phosphatase
HKLHMJLG_00488 4.1e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HKLHMJLG_00489 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HKLHMJLG_00490 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKLHMJLG_00491 6.3e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HKLHMJLG_00492 0.0 yhgF K COG2183 Transcriptional accessory protein
HKLHMJLG_00493 1.7e-14
HKLHMJLG_00494 7.3e-58 ydcK S Belongs to the SprT family
HKLHMJLG_00502 1e-45
HKLHMJLG_00503 1.8e-19 S LXG domain of WXG superfamily
HKLHMJLG_00504 2.5e-105 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKLHMJLG_00505 1.3e-14 A Pre-toxin TG
HKLHMJLG_00507 1.4e-141 yhfP 1.1.1.1 C Alcohol dehydrogenase GroES-like domain
HKLHMJLG_00508 1.6e-63 K BetI-type transcriptional repressor, C-terminal
HKLHMJLG_00509 4.3e-78 K Transcriptional regulator
HKLHMJLG_00510 2.4e-97 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKLHMJLG_00511 1.2e-101 GM NAD(P)H-binding
HKLHMJLG_00512 2.6e-56 azoR I NADPH-dependent FMN reductase
HKLHMJLG_00513 4.3e-45 K Acetyltransferase (GNAT) domain
HKLHMJLG_00514 1.4e-46 ywrO 1.6.5.2 S Flavodoxin-like fold
HKLHMJLG_00515 3.7e-96 ywrO S Flavodoxin-like fold
HKLHMJLG_00517 1.6e-151 S Serine aminopeptidase, S33
HKLHMJLG_00518 5.5e-232 proP EGP Transporter
HKLHMJLG_00519 4.5e-49 ohrR K Transcriptional regulator
HKLHMJLG_00520 3.9e-39 S Domain of unknown function with cystatin-like fold (DUF4467)
HKLHMJLG_00521 6.9e-36 S Domain of unknown function with cystatin-like fold (DUF4467)
HKLHMJLG_00522 1e-72 maoC I N-terminal half of MaoC dehydratase
HKLHMJLG_00523 3.8e-65 yyaQ S YjbR
HKLHMJLG_00524 4.8e-73 ywnA K Transcriptional regulator
HKLHMJLG_00525 6.4e-111 ywnB S NAD(P)H-binding
HKLHMJLG_00527 1.1e-88 K Bacterial regulatory proteins, tetR family
HKLHMJLG_00528 2.6e-111 C Enoyl-(Acyl carrier protein) reductase
HKLHMJLG_00529 2.5e-173 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKLHMJLG_00530 1.3e-176 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HKLHMJLG_00531 1.4e-30 cspL K Cold shock
HKLHMJLG_00532 8e-79 carD K Transcription factor
HKLHMJLG_00533 3.6e-120 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HKLHMJLG_00534 3.5e-100 S Protein of unknown function (DUF2812)
HKLHMJLG_00535 9.8e-52 K Transcriptional regulator PadR-like family
HKLHMJLG_00536 2.9e-173 ybfA 3.4.15.5 K FR47-like protein
HKLHMJLG_00537 1.4e-234 ybfB G COG0477 Permeases of the major facilitator superfamily
HKLHMJLG_00538 7.3e-183 S Patatin-like phospholipase
HKLHMJLG_00539 1.5e-83 S DinB superfamily
HKLHMJLG_00540 6.4e-63 G Cupin domain
HKLHMJLG_00543 1.1e-266 ygaK C COG0277 FAD FMN-containing dehydrogenases
HKLHMJLG_00544 1.3e-78 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKLHMJLG_00545 1.9e-167 czcD P COG1230 Co Zn Cd efflux system component
HKLHMJLG_00546 1.3e-201 trkA P Oxidoreductase
HKLHMJLG_00548 1.8e-98 yrkC G Cupin domain
HKLHMJLG_00549 7.5e-67 ykkA S Protein of unknown function (DUF664)
HKLHMJLG_00550 1.4e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
HKLHMJLG_00552 1.6e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HKLHMJLG_00553 3.1e-52 ydeH
HKLHMJLG_00554 4.6e-169 S Sodium Bile acid symporter family
HKLHMJLG_00555 3.4e-202 adhA 1.1.1.1 C alcohol dehydrogenase
HKLHMJLG_00556 3.6e-67 yraB K helix_turn_helix, mercury resistance
HKLHMJLG_00557 2.1e-222 mleN_2 C antiporter
HKLHMJLG_00558 6.4e-265 K helix_turn_helix gluconate operon transcriptional repressor
HKLHMJLG_00559 3.5e-114 paiB K Transcriptional regulator
HKLHMJLG_00561 5e-105 ksgA1 I Ribosomal RNA adenine dimethylase
HKLHMJLG_00562 5.4e-124 T Transcriptional regulator
HKLHMJLG_00563 1e-185 T PhoQ Sensor
HKLHMJLG_00564 4.9e-103 S SNARE associated Golgi protein
HKLHMJLG_00565 1.6e-179 ydeR EGP Major facilitator Superfamily
HKLHMJLG_00566 4.5e-103 ydeS K Transcriptional regulator
HKLHMJLG_00567 2.2e-157 ydeK EG -transporter
HKLHMJLG_00568 7.3e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKLHMJLG_00569 5.6e-49 yraD M Spore coat protein
HKLHMJLG_00570 2.8e-25 yraE
HKLHMJLG_00571 1.6e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HKLHMJLG_00572 2.2e-63 yraF M Spore coat protein
HKLHMJLG_00573 4.5e-36 yraG
HKLHMJLG_00574 1.5e-108 ybjJ G Major Facilitator Superfamily
HKLHMJLG_00575 9.8e-77 2.7.1.2 GK Transcriptional regulator
HKLHMJLG_00576 2.4e-71 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HKLHMJLG_00577 1.1e-218 ydfH 2.7.13.3 T Histidine kinase
HKLHMJLG_00578 3.7e-111 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKLHMJLG_00579 0.0 ydfJ S drug exporters of the RND superfamily
HKLHMJLG_00580 2.5e-134 puuD S Peptidase C26
HKLHMJLG_00581 5.5e-300 expZ S ABC transporter
HKLHMJLG_00582 1.1e-100 ynaD J Acetyltransferase (GNAT) domain
HKLHMJLG_00583 7.2e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
HKLHMJLG_00584 1.1e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HKLHMJLG_00585 3.9e-210 tcaB EGP Major facilitator Superfamily
HKLHMJLG_00586 3.4e-225 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKLHMJLG_00587 5e-156 K Helix-turn-helix XRE-family like proteins
HKLHMJLG_00588 1.3e-123 ydhB S membrane transporter protein
HKLHMJLG_00589 6.5e-81 bltD 2.3.1.57 K FR47-like protein
HKLHMJLG_00590 2.7e-146 bltR K helix_turn_helix, mercury resistance
HKLHMJLG_00591 8.1e-149 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKLHMJLG_00592 2.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HKLHMJLG_00593 4.4e-105 S Alpha/beta hydrolase family
HKLHMJLG_00594 2.7e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HKLHMJLG_00595 1.4e-119 ydhC K FCD
HKLHMJLG_00596 4.9e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HKLHMJLG_00599 3.7e-265 pbpE V Beta-lactamase
HKLHMJLG_00601 2.5e-98 ydhK M Protein of unknown function (DUF1541)
HKLHMJLG_00602 1.2e-195 pbuE EGP Major facilitator Superfamily
HKLHMJLG_00603 1.3e-133 ydhQ K UTRA
HKLHMJLG_00604 5.3e-119 K FCD
HKLHMJLG_00605 7.4e-217 yeaN P COG2807 Cyanate permease
HKLHMJLG_00606 2.6e-49 sugE P Small Multidrug Resistance protein
HKLHMJLG_00607 2.3e-51 ykkC P Small Multidrug Resistance protein
HKLHMJLG_00608 5.3e-104 yvdT K Transcriptional regulator
HKLHMJLG_00609 9.3e-297 yveA E amino acid
HKLHMJLG_00610 3.2e-166 ydhU P Catalase
HKLHMJLG_00611 4.3e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HKLHMJLG_00612 1.1e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
HKLHMJLG_00613 9.8e-253 iolT EGP Major facilitator Superfamily
HKLHMJLG_00616 3.4e-39 S COG NOG14552 non supervised orthologous group
HKLHMJLG_00617 7.8e-08
HKLHMJLG_00619 1.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HKLHMJLG_00620 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HKLHMJLG_00621 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HKLHMJLG_00622 1.2e-82 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKLHMJLG_00623 4.6e-191 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKLHMJLG_00624 0.0 ydiF S ABC transporter
HKLHMJLG_00625 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HKLHMJLG_00626 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKLHMJLG_00627 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKLHMJLG_00628 1.4e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKLHMJLG_00629 1.7e-27 ydiK S Domain of unknown function (DUF4305)
HKLHMJLG_00630 4.3e-127 ydiL S CAAX protease self-immunity
HKLHMJLG_00631 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKLHMJLG_00632 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKLHMJLG_00634 2.2e-61
HKLHMJLG_00635 0.0 K NB-ARC domain
HKLHMJLG_00636 6.5e-201 gutB 1.1.1.14 E Dehydrogenase
HKLHMJLG_00637 1.3e-249 gutA G MFS/sugar transport protein
HKLHMJLG_00638 1.4e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HKLHMJLG_00639 6.2e-30 yjdJ S Domain of unknown function (DUF4306)
HKLHMJLG_00640 3.9e-114 pspA KT Phage shock protein A
HKLHMJLG_00641 1.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKLHMJLG_00642 1.3e-121 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HKLHMJLG_00643 3.7e-153 ydjI S virion core protein (lumpy skin disease virus)
HKLHMJLG_00644 0.0 yrhL I Acyltransferase family
HKLHMJLG_00645 1.7e-146 rsiV S Protein of unknown function (DUF3298)
HKLHMJLG_00646 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HKLHMJLG_00647 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HKLHMJLG_00648 2.1e-61 ydjM M Lytic transglycolase
HKLHMJLG_00649 2e-133 ydjN U Involved in the tonB-independent uptake of proteins
HKLHMJLG_00651 7.2e-35 ydjO S Cold-inducible protein YdjO
HKLHMJLG_00652 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HKLHMJLG_00653 2.1e-244 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HKLHMJLG_00654 2.1e-152 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKLHMJLG_00655 6.6e-176 yeaC S COG0714 MoxR-like ATPases
HKLHMJLG_00656 7.5e-214 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HKLHMJLG_00657 0.0 yebA E COG1305 Transglutaminase-like enzymes
HKLHMJLG_00658 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HKLHMJLG_00659 3e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HKLHMJLG_00660 1.3e-263 S Domain of unknown function (DUF4179)
HKLHMJLG_00661 6.2e-209 pbuG S permease
HKLHMJLG_00662 5.6e-133 yebC M Membrane
HKLHMJLG_00664 3.4e-92 yebE S UPF0316 protein
HKLHMJLG_00665 5.5e-29 yebG S NETI protein
HKLHMJLG_00666 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKLHMJLG_00667 6.7e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKLHMJLG_00668 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKLHMJLG_00669 1.8e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HKLHMJLG_00670 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKLHMJLG_00671 6.6e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKLHMJLG_00672 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKLHMJLG_00673 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKLHMJLG_00674 2.7e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HKLHMJLG_00675 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKLHMJLG_00676 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HKLHMJLG_00677 3.1e-234 purD 6.3.4.13 F Belongs to the GARS family
HKLHMJLG_00678 1.2e-25 S Protein of unknown function (DUF2892)
HKLHMJLG_00679 0.0 yerA 3.5.4.2 F adenine deaminase
HKLHMJLG_00680 1.4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
HKLHMJLG_00681 2.4e-50 yerC S protein conserved in bacteria
HKLHMJLG_00682 5.1e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HKLHMJLG_00683 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HKLHMJLG_00684 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HKLHMJLG_00685 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKLHMJLG_00686 2.3e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
HKLHMJLG_00687 3.6e-193 yerI S homoserine kinase type II (protein kinase fold)
HKLHMJLG_00688 1.3e-120 sapB S MgtC SapB transporter
HKLHMJLG_00689 2.4e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKLHMJLG_00690 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKLHMJLG_00691 7.9e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKLHMJLG_00692 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKLHMJLG_00693 6.9e-153 yerO K Transcriptional regulator
HKLHMJLG_00694 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKLHMJLG_00695 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKLHMJLG_00696 2.3e-246 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKLHMJLG_00697 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
HKLHMJLG_00698 4.3e-69 3.1.21.3 V Type I restriction modification DNA specificity domain
HKLHMJLG_00699 0.0 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
HKLHMJLG_00700 4.4e-49 S Protein of unknown function, DUF600
HKLHMJLG_00701 4.8e-79 S Protein of unknown function, DUF600
HKLHMJLG_00702 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
HKLHMJLG_00703 5.6e-17
HKLHMJLG_00704 8.1e-255 yobL S Bacterial EndoU nuclease
HKLHMJLG_00705 9.4e-127 yeeN K transcriptional regulatory protein
HKLHMJLG_00707 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
HKLHMJLG_00708 3.3e-45 cotJB S CotJB protein
HKLHMJLG_00709 8.9e-104 cotJC P Spore Coat
HKLHMJLG_00710 3.2e-95 yesJ K Acetyltransferase (GNAT) family
HKLHMJLG_00712 8.7e-122 yetF S membrane
HKLHMJLG_00713 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HKLHMJLG_00714 5.8e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKLHMJLG_00715 3.4e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKLHMJLG_00716 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
HKLHMJLG_00717 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
HKLHMJLG_00718 1.8e-105 yetJ S Belongs to the BI1 family
HKLHMJLG_00719 2.9e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HKLHMJLG_00720 2.6e-208 yetM CH FAD binding domain
HKLHMJLG_00721 7.5e-197 yetN S Protein of unknown function (DUF3900)
HKLHMJLG_00722 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HKLHMJLG_00724 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKLHMJLG_00725 7.9e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
HKLHMJLG_00726 2.4e-172 yfnG 4.2.1.45 M dehydratase
HKLHMJLG_00727 3.2e-180 yfnF M Nucleotide-diphospho-sugar transferase
HKLHMJLG_00728 2.1e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HKLHMJLG_00729 5.6e-188 yfnD M Nucleotide-diphospho-sugar transferase
HKLHMJLG_00730 3e-218 fsr P COG0477 Permeases of the major facilitator superfamily
HKLHMJLG_00731 1.5e-245 yfnA E amino acid
HKLHMJLG_00732 2e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKLHMJLG_00733 9.8e-115 yfmS NT chemotaxis protein
HKLHMJLG_00734 3.7e-165 IQ Enoyl-(Acyl carrier protein) reductase
HKLHMJLG_00735 6.5e-209 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKLHMJLG_00736 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKLHMJLG_00737 6.2e-70 yfmP K transcriptional
HKLHMJLG_00738 2.1e-208 yfmO EGP Major facilitator Superfamily
HKLHMJLG_00739 3.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKLHMJLG_00740 9.4e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HKLHMJLG_00741 1.2e-25 yfmK 2.3.1.128 K acetyltransferase
HKLHMJLG_00742 1.5e-27 yfmK 2.3.1.128 K acetyltransferase
HKLHMJLG_00743 2.2e-190 yfmJ S N-terminal domain of oxidoreductase
HKLHMJLG_00744 1.7e-24 S Protein of unknown function (DUF3212)
HKLHMJLG_00745 1.3e-57 yflT S Heat induced stress protein YflT
HKLHMJLG_00746 1.7e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HKLHMJLG_00747 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
HKLHMJLG_00748 9.3e-29 Q PFAM Collagen triple helix
HKLHMJLG_00749 6.5e-38 Q Collagen triple helix repeat (20 copies)
HKLHMJLG_00751 4.1e-15 Q calcium- and calmodulin-responsive adenylate cyclase activity
HKLHMJLG_00752 8.1e-78 M1-820 Q Collagen triple helix repeat (20 copies)
HKLHMJLG_00753 0.0 ywpD T PhoQ Sensor
HKLHMJLG_00754 8.2e-151 M1-574 T Transcriptional regulatory protein, C terminal
HKLHMJLG_00755 0.0 M1-568 M cell wall anchor domain
HKLHMJLG_00756 2.3e-79 srtA 3.4.22.70 M Sortase family
HKLHMJLG_00757 6.7e-274 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKLHMJLG_00758 4.7e-120 citT T response regulator
HKLHMJLG_00759 7e-178 yflP S Tripartite tricarboxylate transporter family receptor
HKLHMJLG_00760 3.8e-227 citM C Citrate transporter
HKLHMJLG_00761 4.3e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HKLHMJLG_00762 6e-218 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HKLHMJLG_00763 2.2e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HKLHMJLG_00764 4.4e-123 yflK S protein conserved in bacteria
HKLHMJLG_00765 1.5e-14 yflJ S Protein of unknown function (DUF2639)
HKLHMJLG_00766 7e-19 yflI
HKLHMJLG_00767 2e-49 yflH S Protein of unknown function (DUF3243)
HKLHMJLG_00768 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
HKLHMJLG_00769 1.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HKLHMJLG_00770 2.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
HKLHMJLG_00771 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKLHMJLG_00772 7.8e-64 yhdN S Domain of unknown function (DUF1992)
HKLHMJLG_00773 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
HKLHMJLG_00774 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
HKLHMJLG_00775 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
HKLHMJLG_00776 4.3e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKLHMJLG_00777 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HKLHMJLG_00778 7.6e-129 treR K transcriptional
HKLHMJLG_00779 1.3e-122 yfkO C nitroreductase
HKLHMJLG_00780 9.3e-125 yibF S YibE/F-like protein
HKLHMJLG_00781 8.5e-199 yibE S YibE/F-like protein
HKLHMJLG_00782 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HKLHMJLG_00783 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HKLHMJLG_00784 1.5e-186 K helix_turn _helix lactose operon repressor
HKLHMJLG_00785 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKLHMJLG_00786 1.7e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKLHMJLG_00787 1.5e-193 ydiM EGP Major facilitator Superfamily
HKLHMJLG_00788 2.7e-29 yfkK S Belongs to the UPF0435 family
HKLHMJLG_00789 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKLHMJLG_00790 4.5e-52 yfkI S gas vesicle protein
HKLHMJLG_00791 6.8e-145 yihY S Belongs to the UPF0761 family
HKLHMJLG_00792 2.5e-07
HKLHMJLG_00793 1.7e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HKLHMJLG_00794 6.5e-185 cax P COG0387 Ca2 H antiporter
HKLHMJLG_00795 4.2e-144 yfkD S YfkD-like protein
HKLHMJLG_00796 3.3e-147 yfkC M Mechanosensitive ion channel
HKLHMJLG_00797 3e-220 yfkA S YfkB-like domain
HKLHMJLG_00798 4.9e-27 yfjT
HKLHMJLG_00799 4.5e-154 pdaA G deacetylase
HKLHMJLG_00800 2.9e-151 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HKLHMJLG_00801 4.2e-33
HKLHMJLG_00802 1.7e-184 corA P Mediates influx of magnesium ions
HKLHMJLG_00803 2e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HKLHMJLG_00804 5.6e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKLHMJLG_00805 2.3e-50 S YfzA-like protein
HKLHMJLG_00807 2.7e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKLHMJLG_00808 2.1e-90 yfjM S Psort location Cytoplasmic, score
HKLHMJLG_00809 2.9e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKLHMJLG_00810 1.2e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKLHMJLG_00811 1.5e-214 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKLHMJLG_00812 7.3e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKLHMJLG_00813 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HKLHMJLG_00814 4.2e-15 sspH S Belongs to the SspH family
HKLHMJLG_00815 1.3e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HKLHMJLG_00816 1.1e-138 glvR F Helix-turn-helix domain, rpiR family
HKLHMJLG_00817 1.4e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKLHMJLG_00818 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
HKLHMJLG_00819 0.0 yfiB3 V ABC transporter
HKLHMJLG_00820 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKLHMJLG_00821 2.4e-63 mhqP S DoxX
HKLHMJLG_00822 2.6e-160 yfiE 1.13.11.2 S glyoxalase
HKLHMJLG_00823 2.1e-166 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HKLHMJLG_00824 3e-96 padR K transcriptional
HKLHMJLG_00825 6.5e-113 1.6.5.2 S NADPH-dependent FMN reductase
HKLHMJLG_00826 5.7e-184 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HKLHMJLG_00827 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
HKLHMJLG_00828 1.5e-45 yrdF K ribonuclease inhibitor
HKLHMJLG_00829 1.6e-99 yfiT S Belongs to the metal hydrolase YfiT family
HKLHMJLG_00830 1.6e-291 yfiU EGP Major facilitator Superfamily
HKLHMJLG_00831 5.6e-83 yfiV K transcriptional
HKLHMJLG_00832 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKLHMJLG_00833 1.3e-167 yfhB 5.3.3.17 S PhzF family
HKLHMJLG_00834 3.3e-106 yfhC C nitroreductase
HKLHMJLG_00835 2.1e-25 yfhD S YfhD-like protein
HKLHMJLG_00837 5.6e-169 yfhF S nucleoside-diphosphate sugar epimerase
HKLHMJLG_00838 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HKLHMJLG_00839 8.8e-53 yfhH S Protein of unknown function (DUF1811)
HKLHMJLG_00840 1.5e-206 yfhI EGP Major facilitator Superfamily
HKLHMJLG_00842 1.4e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HKLHMJLG_00843 2.2e-44 yfhJ S WVELL protein
HKLHMJLG_00844 1.6e-94 batE T Bacterial SH3 domain homologues
HKLHMJLG_00845 2.6e-34 yfhL S SdpI/YhfL protein family
HKLHMJLG_00846 8.2e-170 yfhM S Alpha/beta hydrolase family
HKLHMJLG_00847 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKLHMJLG_00848 0.0 yfhO S Bacterial membrane protein YfhO
HKLHMJLG_00849 1e-184 yfhP S membrane-bound metal-dependent
HKLHMJLG_00850 2.7e-210 mutY L A G-specific
HKLHMJLG_00851 8.2e-37 yfhS
HKLHMJLG_00852 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKLHMJLG_00854 1.5e-37 ygaB S YgaB-like protein
HKLHMJLG_00855 8.2e-104 ygaC J Belongs to the UPF0374 family
HKLHMJLG_00856 2.5e-306 ygaD V ABC transporter
HKLHMJLG_00857 1.1e-179 ygaE S Membrane
HKLHMJLG_00858 2.3e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HKLHMJLG_00859 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
HKLHMJLG_00860 1.8e-80 perR P Belongs to the Fur family
HKLHMJLG_00861 1.5e-56 ygzB S UPF0295 protein
HKLHMJLG_00862 6.3e-165 ygxA S Nucleotidyltransferase-like
HKLHMJLG_00863 3.4e-39 S COG NOG14552 non supervised orthologous group
HKLHMJLG_00868 7.8e-08
HKLHMJLG_00876 1.6e-08
HKLHMJLG_00880 1.8e-287 C Na+/H+ antiporter family
HKLHMJLG_00881 1.2e-129 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HKLHMJLG_00882 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HKLHMJLG_00883 2.9e-266 ygaK C Berberine and berberine like
HKLHMJLG_00885 1.4e-229 oppA5 E PFAM extracellular solute-binding protein family 5
HKLHMJLG_00886 1e-136 appB P Binding-protein-dependent transport system inner membrane component
HKLHMJLG_00887 9.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHMJLG_00888 3.2e-133 oppD3 P Belongs to the ABC transporter superfamily
HKLHMJLG_00889 9.6e-135 oppF3 E Belongs to the ABC transporter superfamily
HKLHMJLG_00890 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HKLHMJLG_00891 2e-185 S Amidohydrolase
HKLHMJLG_00892 5.1e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HKLHMJLG_00893 1.1e-181 ssuA M Sulfonate ABC transporter
HKLHMJLG_00894 1.2e-144 ssuC P ABC transporter (permease)
HKLHMJLG_00895 1.7e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HKLHMJLG_00896 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKLHMJLG_00897 6.6e-81 ygaO
HKLHMJLG_00898 4.8e-23 K Transcriptional regulator
HKLHMJLG_00900 4.8e-111 yhzB S B3/4 domain
HKLHMJLG_00901 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKLHMJLG_00902 1.8e-175 yhbB S Putative amidase domain
HKLHMJLG_00903 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKLHMJLG_00904 1e-108 yhbD K Protein of unknown function (DUF4004)
HKLHMJLG_00905 7.5e-52 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HKLHMJLG_00906 1.3e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HKLHMJLG_00908 0.0 prkA T Ser protein kinase
HKLHMJLG_00909 2.7e-216 yhbH S Belongs to the UPF0229 family
HKLHMJLG_00910 4.6e-74 yhbI K DNA-binding transcription factor activity
HKLHMJLG_00911 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
HKLHMJLG_00912 8.4e-285 yhcA EGP Major facilitator Superfamily
HKLHMJLG_00913 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
HKLHMJLG_00914 1.4e-54 yhcC
HKLHMJLG_00915 9.6e-53
HKLHMJLG_00916 2.5e-62 yhcF K Transcriptional regulator
HKLHMJLG_00917 1e-125 yhcG V ABC transporter, ATP-binding protein
HKLHMJLG_00918 6.9e-167 yhcH V ABC transporter, ATP-binding protein
HKLHMJLG_00919 4.4e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKLHMJLG_00920 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
HKLHMJLG_00921 1.3e-148 metQ M Belongs to the nlpA lipoprotein family
HKLHMJLG_00922 3.8e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HKLHMJLG_00923 8.4e-222 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKLHMJLG_00924 2.7e-52 yhcM
HKLHMJLG_00925 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKLHMJLG_00926 3.3e-161 yhcP
HKLHMJLG_00927 7.6e-115 yhcQ M Spore coat protein
HKLHMJLG_00928 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKLHMJLG_00929 1.2e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HKLHMJLG_00930 3.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKLHMJLG_00931 1.3e-69 yhcU S Family of unknown function (DUF5365)
HKLHMJLG_00932 2.6e-68 yhcV S COG0517 FOG CBS domain
HKLHMJLG_00933 4.9e-125 yhcW 5.4.2.6 S hydrolase
HKLHMJLG_00934 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKLHMJLG_00935 3.8e-262 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKLHMJLG_00936 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HKLHMJLG_00937 4.5e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HKLHMJLG_00938 7e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKLHMJLG_00939 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HKLHMJLG_00940 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HKLHMJLG_00941 8.5e-207 yhcY 2.7.13.3 T Histidine kinase
HKLHMJLG_00942 1.5e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKLHMJLG_00943 2.5e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
HKLHMJLG_00944 2.5e-39 yhdB S YhdB-like protein
HKLHMJLG_00945 5.3e-53 yhdC S Protein of unknown function (DUF3889)
HKLHMJLG_00946 1e-217 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKLHMJLG_00947 1.9e-74 nsrR K Transcriptional regulator
HKLHMJLG_00948 2e-256 ygxB M Conserved TM helix
HKLHMJLG_00949 1.8e-270 ycgB S Stage V sporulation protein R
HKLHMJLG_00950 4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HKLHMJLG_00951 4.8e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKLHMJLG_00952 7.6e-163 citR K Transcriptional regulator
HKLHMJLG_00953 1.8e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
HKLHMJLG_00954 1.6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKLHMJLG_00955 9.1e-251 yhdG E amino acid
HKLHMJLG_00956 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKLHMJLG_00957 8.1e-45 yhdK S Sigma-M inhibitor protein
HKLHMJLG_00958 5e-201 yhdL S Sigma factor regulator N-terminal
HKLHMJLG_00959 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HKLHMJLG_00960 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HKLHMJLG_00961 1.6e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKLHMJLG_00962 4.3e-71 cueR K transcriptional
HKLHMJLG_00963 7.2e-225 yhdR 2.6.1.1 E Aminotransferase
HKLHMJLG_00964 1.9e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKLHMJLG_00965 4.2e-256 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HKLHMJLG_00966 8.5e-52 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKLHMJLG_00967 2.1e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKLHMJLG_00968 1.7e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKLHMJLG_00970 1.6e-205 yhdY M Mechanosensitive ion channel
HKLHMJLG_00971 1.1e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HKLHMJLG_00972 1.2e-157 yheN G deacetylase
HKLHMJLG_00973 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HKLHMJLG_00974 4.6e-88 pksA K Transcriptional regulator
HKLHMJLG_00975 1.2e-94 ymcC S Membrane
HKLHMJLG_00976 6.2e-85 T universal stress protein
HKLHMJLG_00978 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKLHMJLG_00979 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKLHMJLG_00980 2.6e-109 yheG GM NAD(P)H-binding
HKLHMJLG_00982 2.9e-28 sspB S spore protein
HKLHMJLG_00983 1.7e-36 yheE S Family of unknown function (DUF5342)
HKLHMJLG_00984 1.2e-260 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HKLHMJLG_00985 3.1e-214 yheC HJ YheC/D like ATP-grasp
HKLHMJLG_00986 1.9e-206 yheB S Belongs to the UPF0754 family
HKLHMJLG_00987 1.5e-53 yheA S Belongs to the UPF0342 family
HKLHMJLG_00988 6.8e-204 yhaZ L DNA alkylation repair enzyme
HKLHMJLG_00989 3.3e-158 yhaX S haloacid dehalogenase-like hydrolase
HKLHMJLG_00990 9.3e-294 hemZ H coproporphyrinogen III oxidase
HKLHMJLG_00991 3.2e-250 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
HKLHMJLG_00992 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HKLHMJLG_00993 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HKLHMJLG_00995 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
HKLHMJLG_00996 7.3e-15 S YhzD-like protein
HKLHMJLG_00997 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HKLHMJLG_00998 4.2e-207 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HKLHMJLG_00999 3.8e-237 yhaO L DNA repair exonuclease
HKLHMJLG_01000 0.0 yhaN L AAA domain
HKLHMJLG_01001 1.3e-176 yhaM L Shows a 3'-5' exoribonuclease activity
HKLHMJLG_01002 1.6e-32 yhaL S Sporulation protein YhaL
HKLHMJLG_01003 1.7e-122 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKLHMJLG_01004 7e-95 yhaK S Putative zincin peptidase
HKLHMJLG_01005 3.8e-54 yhaI S Protein of unknown function (DUF1878)
HKLHMJLG_01006 8.6e-113 hpr K Negative regulator of protease production and sporulation
HKLHMJLG_01007 6.2e-39 yhaH S YtxH-like protein
HKLHMJLG_01008 2e-17
HKLHMJLG_01009 3.8e-77 trpP S Tryptophan transporter TrpP
HKLHMJLG_01010 3.8e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKLHMJLG_01011 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HKLHMJLG_01012 1.1e-135 ecsA V transporter (ATP-binding protein)
HKLHMJLG_01013 1.1e-220 ecsB U ABC transporter
HKLHMJLG_01014 3.6e-123 ecsC S EcsC protein family
HKLHMJLG_01015 2.5e-225 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HKLHMJLG_01016 6.9e-243 yhfA C membrane
HKLHMJLG_01017 9.2e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HKLHMJLG_01018 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKLHMJLG_01019 8.6e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HKLHMJLG_01020 6.2e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HKLHMJLG_01021 4.6e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HKLHMJLG_01022 3.2e-101 yhgD K Transcriptional regulator
HKLHMJLG_01023 9.4e-277 yhgE S YhgE Pip N-terminal domain protein
HKLHMJLG_01024 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKLHMJLG_01026 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HKLHMJLG_01027 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKLHMJLG_01028 7.9e-11 yhfH S YhfH-like protein
HKLHMJLG_01029 3.8e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HKLHMJLG_01030 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
HKLHMJLG_01031 1.2e-112 yhfK GM NmrA-like family
HKLHMJLG_01032 6.2e-301 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HKLHMJLG_01033 8.7e-66 yhfM
HKLHMJLG_01034 6e-238 yhfN 3.4.24.84 O Peptidase M48
HKLHMJLG_01035 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HKLHMJLG_01036 1.1e-158 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HKLHMJLG_01037 4e-104 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HKLHMJLG_01038 3.2e-203 vraB 2.3.1.9 I Belongs to the thiolase family
HKLHMJLG_01039 2.3e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HKLHMJLG_01040 9.3e-90 bioY S BioY family
HKLHMJLG_01041 5.9e-196 hemAT NT chemotaxis protein
HKLHMJLG_01042 2.6e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HKLHMJLG_01043 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKLHMJLG_01044 1.3e-32 yhzC S IDEAL
HKLHMJLG_01045 1.9e-109 comK K Competence transcription factor
HKLHMJLG_01047 1e-73
HKLHMJLG_01048 3.9e-68 frataxin S Domain of unknown function (DU1801)
HKLHMJLG_01049 7.4e-67 frataxin S Domain of unknown function (DU1801)
HKLHMJLG_01050 5.3e-92 mepB S MepB protein
HKLHMJLG_01051 1.9e-127 yrpD S Domain of unknown function, YrpD
HKLHMJLG_01052 1.6e-42 yhjA S Excalibur calcium-binding domain
HKLHMJLG_01053 3.3e-47 S Belongs to the UPF0145 family
HKLHMJLG_01054 8.6e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKLHMJLG_01055 1.4e-27 yhjC S Protein of unknown function (DUF3311)
HKLHMJLG_01056 1.7e-60 yhjD
HKLHMJLG_01057 2e-109 yhjE S SNARE associated Golgi protein
HKLHMJLG_01058 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HKLHMJLG_01059 5.4e-278 yhjG CH FAD binding domain
HKLHMJLG_01060 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HKLHMJLG_01061 6.7e-183 abrB S membrane
HKLHMJLG_01062 4.3e-209 blt EGP Major facilitator Superfamily
HKLHMJLG_01063 4.5e-109 K QacR-like protein, C-terminal region
HKLHMJLG_01064 7e-92 yhjR S Rubrerythrin
HKLHMJLG_01065 3e-125 ydfS S Protein of unknown function (DUF421)
HKLHMJLG_01066 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HKLHMJLG_01067 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HKLHMJLG_01068 8.7e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKLHMJLG_01069 0.0 sbcC L COG0419 ATPase involved in DNA repair
HKLHMJLG_01070 1.9e-49 yisB V COG1403 Restriction endonuclease
HKLHMJLG_01071 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
HKLHMJLG_01072 3.3e-65 gerPE S Spore germination protein GerPE
HKLHMJLG_01073 3.1e-23 gerPD S Spore germination protein
HKLHMJLG_01074 1.4e-62 gerPC S Spore germination protein
HKLHMJLG_01075 6.2e-35 gerPB S cell differentiation
HKLHMJLG_01076 8.4e-34 gerPA S Spore germination protein
HKLHMJLG_01077 5e-07 yisI S Spo0E like sporulation regulatory protein
HKLHMJLG_01078 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HKLHMJLG_01079 1.1e-59 yisL S UPF0344 protein
HKLHMJLG_01080 6.5e-87 yisN S Protein of unknown function (DUF2777)
HKLHMJLG_01081 0.0 asnO 6.3.5.4 E Asparagine synthase
HKLHMJLG_01082 4.1e-133 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HKLHMJLG_01083 1.5e-245 yisQ V Mate efflux family protein
HKLHMJLG_01084 4.5e-160 yisR K Transcriptional regulator
HKLHMJLG_01085 3.7e-90 yisT S DinB family
HKLHMJLG_01086 3.5e-74 argO S Lysine exporter protein LysE YggA
HKLHMJLG_01087 9.8e-192 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKLHMJLG_01088 9.5e-59 mcbG S Pentapeptide repeats (9 copies)
HKLHMJLG_01089 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
HKLHMJLG_01090 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HKLHMJLG_01091 6.6e-55 yajQ S Belongs to the UPF0234 family
HKLHMJLG_01092 9e-161 cvfB S protein conserved in bacteria
HKLHMJLG_01093 7.6e-172 yufN S ABC transporter substrate-binding protein PnrA-like
HKLHMJLG_01094 6.9e-234 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HKLHMJLG_01095 5.6e-244 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HKLHMJLG_01097 2.5e-158 yitS S protein conserved in bacteria
HKLHMJLG_01098 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HKLHMJLG_01099 2.9e-81 ipi S Intracellular proteinase inhibitor
HKLHMJLG_01100 4.4e-26 S Protein of unknown function (DUF3813)
HKLHMJLG_01101 3.5e-07
HKLHMJLG_01102 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HKLHMJLG_01103 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HKLHMJLG_01104 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HKLHMJLG_01105 1.4e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HKLHMJLG_01106 7.8e-274 yitY C D-arabinono-1,4-lactone oxidase
HKLHMJLG_01107 9.1e-90 norB G Major Facilitator Superfamily
HKLHMJLG_01108 1.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKLHMJLG_01109 1.6e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKLHMJLG_01110 1.5e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HKLHMJLG_01111 3.1e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HKLHMJLG_01112 4.1e-203 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKLHMJLG_01113 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HKLHMJLG_01114 1.6e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKLHMJLG_01115 1.2e-27 yjzC S YjzC-like protein
HKLHMJLG_01116 1.5e-23 yjzD S Protein of unknown function (DUF2929)
HKLHMJLG_01117 1.7e-139 yjaU I carboxylic ester hydrolase activity
HKLHMJLG_01118 1.5e-106 yjaV
HKLHMJLG_01119 1.9e-166 med S Transcriptional activator protein med
HKLHMJLG_01120 1.1e-26 comZ S ComZ
HKLHMJLG_01121 5.9e-32 yjzB
HKLHMJLG_01122 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKLHMJLG_01123 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKLHMJLG_01124 5.6e-149 yjaZ O Zn-dependent protease
HKLHMJLG_01125 3.3e-183 appD P Belongs to the ABC transporter superfamily
HKLHMJLG_01126 2.4e-60 appF E Belongs to the ABC transporter superfamily
HKLHMJLG_01127 1.5e-109 appF E Belongs to the ABC transporter superfamily
HKLHMJLG_01128 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HKLHMJLG_01129 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHMJLG_01130 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHMJLG_01131 5.5e-146 yjbA S Belongs to the UPF0736 family
HKLHMJLG_01132 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HKLHMJLG_01133 0.0 oppA E ABC transporter substrate-binding protein
HKLHMJLG_01134 4.6e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHMJLG_01135 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHMJLG_01136 2.7e-202 oppD P Belongs to the ABC transporter superfamily
HKLHMJLG_01137 2.5e-172 oppF E Belongs to the ABC transporter superfamily
HKLHMJLG_01138 2.1e-232 S Putative glycosyl hydrolase domain
HKLHMJLG_01139 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKLHMJLG_01140 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKLHMJLG_01141 3.6e-109 yjbE P Integral membrane protein TerC family
HKLHMJLG_01142 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HKLHMJLG_01143 4.7e-221 yjbF S Competence protein
HKLHMJLG_01144 0.0 pepF E oligoendopeptidase F
HKLHMJLG_01145 5.8e-19
HKLHMJLG_01146 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HKLHMJLG_01147 4.8e-72 yjbI S Bacterial-like globin
HKLHMJLG_01148 4.5e-118 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKLHMJLG_01149 4.6e-100 yjbK S protein conserved in bacteria
HKLHMJLG_01150 6e-61 yjbL S Belongs to the UPF0738 family
HKLHMJLG_01151 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
HKLHMJLG_01152 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKLHMJLG_01153 7e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKLHMJLG_01154 1e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HKLHMJLG_01155 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKLHMJLG_01156 5.2e-138 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKLHMJLG_01157 1.9e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HKLHMJLG_01158 2.9e-212 thiO 1.4.3.19 E Glycine oxidase
HKLHMJLG_01159 1.4e-30 thiS H Thiamine biosynthesis
HKLHMJLG_01160 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HKLHMJLG_01161 9.9e-191 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKLHMJLG_01162 1.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKLHMJLG_01163 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HKLHMJLG_01164 3e-89 yjbX S Spore coat protein
HKLHMJLG_01165 6.7e-83 cotZ S Spore coat protein
HKLHMJLG_01166 4.6e-93 cotY S Spore coat protein Z
HKLHMJLG_01167 1.5e-70 cotX S Spore Coat Protein X and V domain
HKLHMJLG_01168 6.8e-21 cotW
HKLHMJLG_01169 7e-52 cotV S Spore Coat Protein X and V domain
HKLHMJLG_01170 2.1e-55 yjcA S Protein of unknown function (DUF1360)
HKLHMJLG_01174 3.8e-38 spoVIF S Stage VI sporulation protein F
HKLHMJLG_01175 0.0 yjcD 3.6.4.12 L DNA helicase
HKLHMJLG_01176 2.1e-36
HKLHMJLG_01177 5.7e-143 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HKLHMJLG_01178 4e-125 S ABC-2 type transporter
HKLHMJLG_01179 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
HKLHMJLG_01180 9.4e-36 K SpoVT / AbrB like domain
HKLHMJLG_01182 5e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKLHMJLG_01183 1.2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HKLHMJLG_01184 5.5e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
HKLHMJLG_01185 2.8e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKLHMJLG_01186 2.6e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKLHMJLG_01188 1.1e-31 L Belongs to the 'phage' integrase family
HKLHMJLG_01189 8.7e-31
HKLHMJLG_01190 7.3e-256 yobL S Bacterial EndoU nuclease
HKLHMJLG_01192 3.5e-59 E Glyoxalase-like domain
HKLHMJLG_01193 1.1e-164 bla 3.5.2.6 V beta-lactamase
HKLHMJLG_01194 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
HKLHMJLG_01195 5.4e-251 yfjF EGP Belongs to the major facilitator superfamily
HKLHMJLG_01196 1.4e-81 napB K helix_turn_helix multiple antibiotic resistance protein
HKLHMJLG_01197 1.1e-219 ganA 3.2.1.89 G arabinogalactan
HKLHMJLG_01198 5.8e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HKLHMJLG_01199 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKLHMJLG_01200 2.2e-218 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKLHMJLG_01201 4.7e-311 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMJLG_01202 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
HKLHMJLG_01203 7.3e-285 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HKLHMJLG_01204 2.2e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
HKLHMJLG_01205 1.3e-125 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HKLHMJLG_01206 1.5e-145 N Kelch motif
HKLHMJLG_01208 8.1e-106 yhiD S MgtC SapB transporter
HKLHMJLG_01210 7.5e-22 yjfB S Putative motility protein
HKLHMJLG_01211 3.6e-67 T PhoQ Sensor
HKLHMJLG_01212 2.4e-101 yjgB S Domain of unknown function (DUF4309)
HKLHMJLG_01213 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HKLHMJLG_01214 4.3e-92 yjgD S Protein of unknown function (DUF1641)
HKLHMJLG_01215 9.4e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HKLHMJLG_01216 3e-223 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HKLHMJLG_01217 6.8e-29
HKLHMJLG_01218 3.2e-147 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HKLHMJLG_01219 4.6e-124 ybbM S transport system, permease component
HKLHMJLG_01220 1.5e-132 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
HKLHMJLG_01221 3.6e-177 yjlA EG Putative multidrug resistance efflux transporter
HKLHMJLG_01222 8.9e-92 yjlB S Cupin domain
HKLHMJLG_01223 7e-66 yjlC S Protein of unknown function (DUF1641)
HKLHMJLG_01224 3.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HKLHMJLG_01225 5.6e-277 uxaC 5.3.1.12 G glucuronate isomerase
HKLHMJLG_01226 4.3e-253 yjmB G symporter YjmB
HKLHMJLG_01227 6.4e-182 exuR K transcriptional
HKLHMJLG_01228 5.6e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HKLHMJLG_01229 5.4e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HKLHMJLG_01230 1e-87 T Transcriptional regulatory protein, C terminal
HKLHMJLG_01231 2e-130 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HKLHMJLG_01232 3.1e-106 V ABC transporter, ATP-binding protein
HKLHMJLG_01233 6.5e-67 S ABC-2 family transporter protein
HKLHMJLG_01235 2.2e-46 narQ 2.7.13.3 T Histidine kinase
HKLHMJLG_01236 9.2e-60 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKLHMJLG_01238 1.1e-299 lcnDR2 V Lanthionine synthetase C-like protein
HKLHMJLG_01239 1.1e-218 lanT 3.6.3.27 V Peptidase C39 family
HKLHMJLG_01242 7.7e-204 salB V Domain of unknown function (DUF4135)
HKLHMJLG_01243 8.7e-131 MA20_18170 S membrane transporter protein
HKLHMJLG_01244 2.1e-79 yjoA S DinB family
HKLHMJLG_01245 4.9e-215 S response regulator aspartate phosphatase
HKLHMJLG_01247 5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HKLHMJLG_01248 4.7e-61 yjqA S Bacterial PH domain
HKLHMJLG_01249 3.6e-111 yjqB S phage-related replication protein
HKLHMJLG_01250 7.8e-111 xkdA E IrrE N-terminal-like domain
HKLHMJLG_01251 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
HKLHMJLG_01253 8.5e-153 xkdC L Bacterial dnaA protein
HKLHMJLG_01256 2e-10 yqaO S Phage-like element PBSX protein XtrA
HKLHMJLG_01257 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HKLHMJLG_01258 8.9e-110 xtmA L phage terminase small subunit
HKLHMJLG_01259 1e-208 xtmB S phage terminase, large subunit
HKLHMJLG_01260 7.9e-242 yqbA S portal protein
HKLHMJLG_01261 1.7e-90 xkdF 2.1.1.72 L Putative phage serine protease XkdF
HKLHMJLG_01262 1e-157 xkdG S Phage capsid family
HKLHMJLG_01263 7.4e-46 yqbG S Protein of unknown function (DUF3199)
HKLHMJLG_01264 5.5e-43 yqbH S Domain of unknown function (DUF3599)
HKLHMJLG_01265 1.4e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
HKLHMJLG_01266 2.2e-57 xkdJ
HKLHMJLG_01267 3.1e-14
HKLHMJLG_01268 1.1e-224 xkdK S Phage tail sheath C-terminal domain
HKLHMJLG_01269 2e-74 xkdM S Phage tail tube protein
HKLHMJLG_01270 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
HKLHMJLG_01271 3.4e-19
HKLHMJLG_01272 2.6e-189 xkdO L Transglycosylase SLT domain
HKLHMJLG_01273 1.9e-110 xkdP S Lysin motif
HKLHMJLG_01274 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
HKLHMJLG_01275 7.2e-32 xkdR S Protein of unknown function (DUF2577)
HKLHMJLG_01276 7.2e-58 xkdS S Protein of unknown function (DUF2634)
HKLHMJLG_01277 4.3e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HKLHMJLG_01278 5.5e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HKLHMJLG_01279 1.2e-26
HKLHMJLG_01280 3.6e-187
HKLHMJLG_01282 1.7e-30 xkdX
HKLHMJLG_01283 1.1e-136 xepA
HKLHMJLG_01284 8.7e-38 xhlA S Haemolysin XhlA
HKLHMJLG_01285 1.3e-38 xhlB S SPP1 phage holin
HKLHMJLG_01286 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKLHMJLG_01287 8.7e-23 spoIISB S Stage II sporulation protein SB
HKLHMJLG_01288 1.7e-134 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HKLHMJLG_01289 2e-175 pit P phosphate transporter
HKLHMJLG_01290 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HKLHMJLG_01291 3.8e-243 steT E amino acid
HKLHMJLG_01292 5e-184 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HKLHMJLG_01293 3.9e-309 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKLHMJLG_01294 6.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKLHMJLG_01296 7.3e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKLHMJLG_01297 1.1e-284 yubD P Major Facilitator Superfamily
HKLHMJLG_01299 6.5e-156 dppA E D-aminopeptidase
HKLHMJLG_01300 5.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHMJLG_01301 1.9e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHMJLG_01302 5.4e-192 dppD P Belongs to the ABC transporter superfamily
HKLHMJLG_01303 0.0 dppE E ABC transporter substrate-binding protein
HKLHMJLG_01304 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HKLHMJLG_01305 1.7e-204 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HKLHMJLG_01306 7e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HKLHMJLG_01307 1.5e-183 ykfD E Belongs to the ABC transporter superfamily
HKLHMJLG_01308 3.9e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
HKLHMJLG_01309 7.7e-160 ykgA E Amidinotransferase
HKLHMJLG_01310 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HKLHMJLG_01311 7.9e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKLHMJLG_01312 9.4e-53 ykkC P Multidrug resistance protein
HKLHMJLG_01313 3.4e-49 ykkD P Multidrug resistance protein
HKLHMJLG_01314 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HKLHMJLG_01315 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKLHMJLG_01316 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKLHMJLG_01317 1.4e-69 ohrA O Organic hydroperoxide resistance protein
HKLHMJLG_01318 6.1e-88 ohrR K COG1846 Transcriptional regulators
HKLHMJLG_01319 4.2e-71 ohrB O Organic hydroperoxide resistance protein
HKLHMJLG_01320 9.5e-61 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKLHMJLG_01322 3.4e-216 M Glycosyl transferase family 2
HKLHMJLG_01323 2.3e-132 M PFAM Collagen triple helix repeat (20 copies)
HKLHMJLG_01324 1.1e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
HKLHMJLG_01325 1.4e-119 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HKLHMJLG_01326 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKLHMJLG_01327 2.9e-176 isp O Belongs to the peptidase S8 family
HKLHMJLG_01328 5.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKLHMJLG_01329 3.5e-132 ykoC P Cobalt transport protein
HKLHMJLG_01330 3.8e-309 P ABC transporter, ATP-binding protein
HKLHMJLG_01331 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HKLHMJLG_01332 1e-245 ydhD M Glycosyl hydrolase
HKLHMJLG_01334 2.2e-238 mgtE P Acts as a magnesium transporter
HKLHMJLG_01335 5.4e-53 tnrA K transcriptional
HKLHMJLG_01336 3.2e-16
HKLHMJLG_01337 3.1e-26 ykoL
HKLHMJLG_01338 1.1e-80 ykoM K transcriptional
HKLHMJLG_01339 3.7e-99 ykoP G polysaccharide deacetylase
HKLHMJLG_01340 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HKLHMJLG_01341 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HKLHMJLG_01342 4.1e-101 ykoX S membrane-associated protein
HKLHMJLG_01343 8.6e-134 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HKLHMJLG_01344 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKLHMJLG_01345 8.1e-120 rsgI S Anti-sigma factor N-terminus
HKLHMJLG_01346 2.5e-26 sspD S small acid-soluble spore protein
HKLHMJLG_01347 7.8e-126 ykrK S Domain of unknown function (DUF1836)
HKLHMJLG_01348 9.2e-156 htpX O Belongs to the peptidase M48B family
HKLHMJLG_01349 4.3e-242 ktrB P COG0168 Trk-type K transport systems, membrane components
HKLHMJLG_01350 2.9e-114 ydfR S Protein of unknown function (DUF421)
HKLHMJLG_01351 7.9e-24 ykzE
HKLHMJLG_01352 2.9e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HKLHMJLG_01353 0.0 kinE 2.7.13.3 T Histidine kinase
HKLHMJLG_01354 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKLHMJLG_01356 4.1e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HKLHMJLG_01357 1.1e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HKLHMJLG_01358 3.8e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKLHMJLG_01359 1.1e-228 mtnE 2.6.1.83 E Aminotransferase
HKLHMJLG_01360 1e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HKLHMJLG_01361 1.9e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HKLHMJLG_01362 1.4e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HKLHMJLG_01363 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HKLHMJLG_01364 3.4e-10 S Spo0E like sporulation regulatory protein
HKLHMJLG_01365 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKLHMJLG_01366 3.6e-76 ykvE K transcriptional
HKLHMJLG_01367 2.7e-127 motB N Flagellar motor protein
HKLHMJLG_01368 1.1e-136 motA N flagellar motor
HKLHMJLG_01369 0.0 clpE O Belongs to the ClpA ClpB family
HKLHMJLG_01370 1.4e-184 ykvI S membrane
HKLHMJLG_01371 6.5e-191
HKLHMJLG_01372 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HKLHMJLG_01373 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HKLHMJLG_01374 1.9e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HKLHMJLG_01375 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HKLHMJLG_01376 5.1e-60 ykvN K Transcriptional regulator
HKLHMJLG_01377 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
HKLHMJLG_01378 2.7e-31 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HKLHMJLG_01379 3.5e-45 ykvR S Protein of unknown function (DUF3219)
HKLHMJLG_01380 7.8e-25 ykvS S protein conserved in bacteria
HKLHMJLG_01381 6e-28
HKLHMJLG_01382 6.3e-111 ykvT 3.5.1.28 M Cell Wall Hydrolase
HKLHMJLG_01383 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKLHMJLG_01384 2.7e-88 stoA CO thiol-disulfide
HKLHMJLG_01385 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HKLHMJLG_01386 4.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HKLHMJLG_01388 8.6e-176 ykvZ 5.1.1.1 K Transcriptional regulator
HKLHMJLG_01389 5.1e-156 glcT K antiterminator
HKLHMJLG_01390 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKLHMJLG_01391 2.1e-39 ptsH G phosphocarrier protein HPr
HKLHMJLG_01392 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKLHMJLG_01393 6.1e-38 splA S Transcriptional regulator
HKLHMJLG_01394 2.9e-190 splB 4.1.99.14 L Spore photoproduct lyase
HKLHMJLG_01395 1.4e-265 mcpC NT chemotaxis protein
HKLHMJLG_01396 5.6e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HKLHMJLG_01397 6.8e-115 ykwD J protein with SCP PR1 domains
HKLHMJLG_01398 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HKLHMJLG_01399 6.8e-291 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
HKLHMJLG_01400 3.9e-215 patA 2.6.1.1 E Aminotransferase
HKLHMJLG_01401 2.3e-09
HKLHMJLG_01402 2.6e-166 cheV 2.7.13.3 T Chemotaxis protein CheV
HKLHMJLG_01403 7e-83 ykyB S YkyB-like protein
HKLHMJLG_01404 7.8e-241 ykuC EGP Major facilitator Superfamily
HKLHMJLG_01405 3.2e-89 ykuD S protein conserved in bacteria
HKLHMJLG_01406 2.3e-156 ykuE S Metallophosphoesterase
HKLHMJLG_01407 4.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKLHMJLG_01408 1.5e-233 ykuI T Diguanylate phosphodiesterase
HKLHMJLG_01409 3.9e-37 ykuJ S protein conserved in bacteria
HKLHMJLG_01410 4.9e-93 ykuK S Ribonuclease H-like
HKLHMJLG_01411 2.5e-26 ykzF S Antirepressor AbbA
HKLHMJLG_01412 1e-75 ykuL S CBS domain
HKLHMJLG_01413 4.6e-168 ccpC K Transcriptional regulator
HKLHMJLG_01414 1.3e-89 fld C Flavodoxin
HKLHMJLG_01415 4.5e-171 ykuO
HKLHMJLG_01416 9.3e-80 fld C Flavodoxin
HKLHMJLG_01417 8.8e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKLHMJLG_01418 7.6e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKLHMJLG_01419 4.8e-38 ykuS S Belongs to the UPF0180 family
HKLHMJLG_01420 5.8e-141 ykuT M Mechanosensitive ion channel
HKLHMJLG_01421 1.6e-79 ykuV CO thiol-disulfide
HKLHMJLG_01422 1.5e-98 rok K Repressor of ComK
HKLHMJLG_01423 1.9e-162 yknT
HKLHMJLG_01424 7.4e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HKLHMJLG_01425 8.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKLHMJLG_01426 1.3e-243 moeA 2.10.1.1 H molybdopterin
HKLHMJLG_01427 2.9e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HKLHMJLG_01428 2.3e-81 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HKLHMJLG_01429 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HKLHMJLG_01430 1.2e-105 yknW S Yip1 domain
HKLHMJLG_01431 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKLHMJLG_01432 6.1e-123 macB V ABC transporter, ATP-binding protein
HKLHMJLG_01433 6.4e-213 yknZ V ABC transporter (permease)
HKLHMJLG_01434 1.1e-133 fruR K Transcriptional regulator
HKLHMJLG_01435 4e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HKLHMJLG_01436 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HKLHMJLG_01437 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKLHMJLG_01438 2.6e-37 ykoA
HKLHMJLG_01439 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKLHMJLG_01440 5.3e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKLHMJLG_01441 6.5e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HKLHMJLG_01442 5.5e-12 S Uncharacterized protein YkpC
HKLHMJLG_01443 6.9e-184 mreB D Rod-share determining protein MreBH
HKLHMJLG_01444 2.1e-45 abrB K of stationary sporulation gene expression
HKLHMJLG_01445 1.4e-245 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKLHMJLG_01446 4.1e-150 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HKLHMJLG_01447 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
HKLHMJLG_01448 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HKLHMJLG_01449 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKLHMJLG_01450 8.2e-31 ykzG S Belongs to the UPF0356 family
HKLHMJLG_01451 4.7e-148 ykrA S hydrolases of the HAD superfamily
HKLHMJLG_01452 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKLHMJLG_01454 5.9e-104 recN L Putative cell-wall binding lipoprotein
HKLHMJLG_01455 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKLHMJLG_01456 0.0 Q Polyketide synthase of type I
HKLHMJLG_01457 0.0 Q polyketide synthase
HKLHMJLG_01458 0.0 Q Polyketide synthase of type I
HKLHMJLG_01459 0.0 Q Polyketide synthase of type I
HKLHMJLG_01460 0.0 Q Polyketide synthase of type I
HKLHMJLG_01461 0.0 Q Polyketide synthase of type I
HKLHMJLG_01462 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
HKLHMJLG_01463 1.1e-211 V Beta-lactamase
HKLHMJLG_01464 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKLHMJLG_01465 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKLHMJLG_01466 3.4e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKLHMJLG_01467 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKLHMJLG_01468 8e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HKLHMJLG_01469 3.7e-140 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
HKLHMJLG_01470 1.6e-277 speA 4.1.1.19 E Arginine
HKLHMJLG_01471 1.6e-42 yktA S Belongs to the UPF0223 family
HKLHMJLG_01472 4.9e-119 yktB S Belongs to the UPF0637 family
HKLHMJLG_01473 9.7e-25 ykzI
HKLHMJLG_01474 2.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
HKLHMJLG_01475 1.5e-82 ykzC S Acetyltransferase (GNAT) family
HKLHMJLG_01476 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HKLHMJLG_01477 2.8e-13 sigC S Putative zinc-finger
HKLHMJLG_01478 6.3e-39 ylaE
HKLHMJLG_01479 6.7e-24 S Family of unknown function (DUF5325)
HKLHMJLG_01480 0.0 typA T GTP-binding protein TypA
HKLHMJLG_01481 1.7e-48 ylaH S YlaH-like protein
HKLHMJLG_01482 1e-33 ylaI S protein conserved in bacteria
HKLHMJLG_01483 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKLHMJLG_01484 2.2e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HKLHMJLG_01485 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HKLHMJLG_01486 5.2e-47 glsA 3.5.1.2 E Belongs to the glutaminase family
HKLHMJLG_01497 3e-10 K Cro/C1-type HTH DNA-binding domain
HKLHMJLG_01501 1.6e-22 K Helix-turn-helix domain
HKLHMJLG_01503 4.9e-43
HKLHMJLG_01504 2.4e-23
HKLHMJLG_01505 4.1e-182 I Pfam Lipase (class 3)
HKLHMJLG_01506 5.1e-28 S Protein of unknown function (DUF1433)
HKLHMJLG_01508 1e-159 S aspartate phosphatase
HKLHMJLG_01509 1.9e-22
HKLHMJLG_01510 0.0 S Pfam Transposase IS66
HKLHMJLG_01511 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKLHMJLG_01512 6e-193 S peptidoglycan catabolic process
HKLHMJLG_01513 1.1e-31 L GIY-YIG catalytic domain
HKLHMJLG_01514 3.7e-48 L Phage integrase, N-terminal SAM-like domain
HKLHMJLG_01520 6.2e-08
HKLHMJLG_01521 1.1e-54
HKLHMJLG_01522 6.2e-10 S Phage uncharacterised protein (Phage_XkdX)
HKLHMJLG_01524 3.8e-49 S Domain of unknown function (DUF2479)
HKLHMJLG_01527 2.4e-189
HKLHMJLG_01529 5.8e-55
HKLHMJLG_01540 1.3e-73 L Recombinase zinc beta ribbon domain
HKLHMJLG_01541 3.8e-122 glsA 3.5.1.2 E Belongs to the glutaminase family
HKLHMJLG_01542 8.7e-44 ylaN S Belongs to the UPF0358 family
HKLHMJLG_01543 9e-215 ftsW D Belongs to the SEDS family
HKLHMJLG_01544 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKLHMJLG_01545 1e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HKLHMJLG_01546 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HKLHMJLG_01547 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HKLHMJLG_01548 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKLHMJLG_01549 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HKLHMJLG_01550 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HKLHMJLG_01551 9.7e-166 ctaG S cytochrome c oxidase
HKLHMJLG_01552 8.5e-60 ylbA S YugN-like family
HKLHMJLG_01553 2.2e-73 ylbB T COG0517 FOG CBS domain
HKLHMJLG_01554 2.1e-199 ylbC S protein with SCP PR1 domains
HKLHMJLG_01555 6.5e-56 ylbD S Putative coat protein
HKLHMJLG_01556 1.1e-36 ylbE S YlbE-like protein
HKLHMJLG_01557 1.2e-71 ylbF S Belongs to the UPF0342 family
HKLHMJLG_01558 5.5e-43 ylbG S UPF0298 protein
HKLHMJLG_01560 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
HKLHMJLG_01561 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKLHMJLG_01562 2.8e-216 ylbJ S Sporulation integral membrane protein YlbJ
HKLHMJLG_01563 8.9e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
HKLHMJLG_01564 8.8e-187 ylbL T Belongs to the peptidase S16 family
HKLHMJLG_01565 8.9e-133 L Molecular Function DNA binding, Biological Process DNA recombination
HKLHMJLG_01566 1.1e-53 L COG2963 Transposase and inactivated derivatives
HKLHMJLG_01567 2.4e-231 ylbM S Belongs to the UPF0348 family
HKLHMJLG_01568 2.7e-91 yceD S metal-binding, possibly nucleic acid-binding protein
HKLHMJLG_01569 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HKLHMJLG_01570 1.2e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HKLHMJLG_01571 1.2e-88 ylbP K n-acetyltransferase
HKLHMJLG_01572 7.7e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKLHMJLG_01573 2.3e-311 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HKLHMJLG_01574 8.9e-78 mraZ K Belongs to the MraZ family
HKLHMJLG_01575 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKLHMJLG_01576 8.3e-52 ftsL D Essential cell division protein
HKLHMJLG_01577 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HKLHMJLG_01578 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HKLHMJLG_01579 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKLHMJLG_01580 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKLHMJLG_01581 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKLHMJLG_01582 2.8e-185 spoVE D Belongs to the SEDS family
HKLHMJLG_01583 7.9e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKLHMJLG_01584 3.7e-168 murB 1.3.1.98 M cell wall formation
HKLHMJLG_01585 8.7e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKLHMJLG_01586 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKLHMJLG_01587 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKLHMJLG_01588 0.0 bpr O COG1404 Subtilisin-like serine proteases
HKLHMJLG_01589 2.7e-158 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HKLHMJLG_01590 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKLHMJLG_01591 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKLHMJLG_01592 2.9e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HKLHMJLG_01593 4.2e-255 argE 3.5.1.16 E Acetylornithine deacetylase
HKLHMJLG_01594 2.2e-38 ylmC S sporulation protein
HKLHMJLG_01595 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HKLHMJLG_01596 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKLHMJLG_01597 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKLHMJLG_01598 5.2e-41 yggT S membrane
HKLHMJLG_01599 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HKLHMJLG_01600 8.9e-68 divIVA D Cell division initiation protein
HKLHMJLG_01601 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKLHMJLG_01602 3.4e-64 dksA T COG1734 DnaK suppressor protein
HKLHMJLG_01603 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKLHMJLG_01604 2.3e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKLHMJLG_01605 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKLHMJLG_01606 1.8e-232 pyrP F Xanthine uracil
HKLHMJLG_01607 5.3e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HKLHMJLG_01608 5e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKLHMJLG_01609 2.1e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKLHMJLG_01610 0.0 carB 6.3.5.5 F Belongs to the CarB family
HKLHMJLG_01611 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HKLHMJLG_01612 3.9e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKLHMJLG_01613 1.4e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKLHMJLG_01614 5.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKLHMJLG_01616 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HKLHMJLG_01617 1.7e-177 cysP P phosphate transporter
HKLHMJLG_01618 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HKLHMJLG_01619 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HKLHMJLG_01620 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HKLHMJLG_01621 5.8e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HKLHMJLG_01622 9e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HKLHMJLG_01623 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HKLHMJLG_01624 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HKLHMJLG_01625 7.7e-155 yloC S stress-induced protein
HKLHMJLG_01626 1.5e-40 ylzA S Belongs to the UPF0296 family
HKLHMJLG_01627 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HKLHMJLG_01628 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKLHMJLG_01629 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKLHMJLG_01630 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKLHMJLG_01631 1.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKLHMJLG_01632 3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKLHMJLG_01633 1.1e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKLHMJLG_01634 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKLHMJLG_01635 1.7e-139 stp 3.1.3.16 T phosphatase
HKLHMJLG_01636 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HKLHMJLG_01637 5.7e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKLHMJLG_01638 2.3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HKLHMJLG_01639 2e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
HKLHMJLG_01640 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HKLHMJLG_01641 5.5e-59 asp S protein conserved in bacteria
HKLHMJLG_01642 1.4e-303 yloV S kinase related to dihydroxyacetone kinase
HKLHMJLG_01643 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HKLHMJLG_01644 7.1e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HKLHMJLG_01645 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKLHMJLG_01646 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HKLHMJLG_01647 6.2e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKLHMJLG_01648 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKLHMJLG_01649 4.6e-129 IQ reductase
HKLHMJLG_01650 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKLHMJLG_01651 1.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKLHMJLG_01652 0.0 smc D Required for chromosome condensation and partitioning
HKLHMJLG_01653 8.3e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKLHMJLG_01654 2.1e-140 S Phosphotransferase enzyme family
HKLHMJLG_01655 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKLHMJLG_01656 2.4e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKLHMJLG_01657 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HKLHMJLG_01658 1.7e-35 ylqC S Belongs to the UPF0109 family
HKLHMJLG_01659 1.3e-61 ylqD S YlqD protein
HKLHMJLG_01660 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKLHMJLG_01661 8.3e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HKLHMJLG_01662 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKLHMJLG_01663 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKLHMJLG_01664 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKLHMJLG_01665 2.9e-307 ylqG
HKLHMJLG_01666 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HKLHMJLG_01667 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HKLHMJLG_01668 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKLHMJLG_01669 2.1e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HKLHMJLG_01670 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKLHMJLG_01671 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKLHMJLG_01672 6.1e-171 xerC L tyrosine recombinase XerC
HKLHMJLG_01673 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKLHMJLG_01674 1.6e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKLHMJLG_01675 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HKLHMJLG_01676 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HKLHMJLG_01677 2.4e-75 flgC N Belongs to the flagella basal body rod proteins family
HKLHMJLG_01678 2.5e-31 fliE N Flagellar hook-basal body
HKLHMJLG_01679 1.4e-263 fliF N The M ring may be actively involved in energy transduction
HKLHMJLG_01680 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HKLHMJLG_01681 3.7e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HKLHMJLG_01682 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HKLHMJLG_01683 4.5e-71 fliJ N Flagellar biosynthesis chaperone
HKLHMJLG_01684 4.4e-48 ylxF S MgtE intracellular N domain
HKLHMJLG_01685 1.2e-204 fliK N Flagellar hook-length control protein
HKLHMJLG_01686 1.4e-72 flgD N Flagellar basal body rod modification protein
HKLHMJLG_01687 4e-139 flgG N Flagellar basal body rod
HKLHMJLG_01688 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
HKLHMJLG_01689 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HKLHMJLG_01690 9.4e-190 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HKLHMJLG_01691 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HKLHMJLG_01692 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
HKLHMJLG_01693 5.7e-110 fliP N Plays a role in the flagellum-specific transport system
HKLHMJLG_01694 2e-37 fliQ N Role in flagellar biosynthesis
HKLHMJLG_01695 4e-131 fliR N Flagellar biosynthetic protein FliR
HKLHMJLG_01696 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HKLHMJLG_01697 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HKLHMJLG_01698 1.1e-192 flhF N Flagellar biosynthesis regulator FlhF
HKLHMJLG_01699 1.2e-155 flhG D Belongs to the ParA family
HKLHMJLG_01700 2.5e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HKLHMJLG_01701 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HKLHMJLG_01702 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
HKLHMJLG_01703 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HKLHMJLG_01704 8.6e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HKLHMJLG_01705 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKLHMJLG_01706 3.1e-54 ylxL
HKLHMJLG_01707 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HKLHMJLG_01708 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKLHMJLG_01709 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HKLHMJLG_01710 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKLHMJLG_01711 2.9e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKLHMJLG_01712 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
HKLHMJLG_01713 7.3e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HKLHMJLG_01714 1.7e-232 rasP M zinc metalloprotease
HKLHMJLG_01715 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKLHMJLG_01716 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKLHMJLG_01717 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
HKLHMJLG_01718 5.4e-206 nusA K Participates in both transcription termination and antitermination
HKLHMJLG_01719 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
HKLHMJLG_01720 1.8e-47 ylxQ J ribosomal protein
HKLHMJLG_01721 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKLHMJLG_01722 3.9e-44 ylxP S protein conserved in bacteria
HKLHMJLG_01723 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKLHMJLG_01724 5.2e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKLHMJLG_01725 9.6e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HKLHMJLG_01726 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKLHMJLG_01727 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKLHMJLG_01728 8e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HKLHMJLG_01729 1.4e-234 pepR S Belongs to the peptidase M16 family
HKLHMJLG_01730 2.6e-42 ymxH S YlmC YmxH family
HKLHMJLG_01731 3.6e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HKLHMJLG_01732 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HKLHMJLG_01733 1.7e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKLHMJLG_01734 3.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HKLHMJLG_01735 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKLHMJLG_01736 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKLHMJLG_01737 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HKLHMJLG_01738 6.3e-31 S YlzJ-like protein
HKLHMJLG_01739 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HKLHMJLG_01740 1.8e-133 ymfC K Transcriptional regulator
HKLHMJLG_01741 6.5e-227 ymfD EGP Major facilitator Superfamily
HKLHMJLG_01742 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
HKLHMJLG_01743 0.0 ydgH S drug exporters of the RND superfamily
HKLHMJLG_01744 3.6e-238 ymfF S Peptidase M16
HKLHMJLG_01745 6.4e-243 ymfH S zinc protease
HKLHMJLG_01746 4.6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HKLHMJLG_01747 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
HKLHMJLG_01748 3.5e-143 ymfK S Protein of unknown function (DUF3388)
HKLHMJLG_01749 2.7e-123 ymfM S protein conserved in bacteria
HKLHMJLG_01750 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKLHMJLG_01751 2.4e-231 cinA 3.5.1.42 S Belongs to the CinA family
HKLHMJLG_01752 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKLHMJLG_01753 1.1e-193 pbpX V Beta-lactamase
HKLHMJLG_01754 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
HKLHMJLG_01755 4.9e-153 ymdB S protein conserved in bacteria
HKLHMJLG_01756 1.2e-36 spoVS S Stage V sporulation protein S
HKLHMJLG_01757 3.5e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HKLHMJLG_01758 5.1e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HKLHMJLG_01759 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKLHMJLG_01760 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HKLHMJLG_01761 1.7e-88 cotE S Spore coat protein
HKLHMJLG_01762 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKLHMJLG_01763 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKLHMJLG_01765 3.9e-130 pksB 3.1.2.6 S Polyketide biosynthesis
HKLHMJLG_01766 1.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKLHMJLG_01767 3.6e-182 pksD Q Acyl transferase domain
HKLHMJLG_01768 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKLHMJLG_01769 1.3e-35 acpK IQ Phosphopantetheine attachment site
HKLHMJLG_01770 1.9e-244 pksG 2.3.3.10 I synthase
HKLHMJLG_01771 1.4e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
HKLHMJLG_01772 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HKLHMJLG_01773 0.0 rhiB IQ polyketide synthase
HKLHMJLG_01774 0.0 Q Polyketide synthase of type I
HKLHMJLG_01775 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HKLHMJLG_01776 0.0 dhbF IQ polyketide synthase
HKLHMJLG_01777 0.0 pks13 HQ Beta-ketoacyl synthase
HKLHMJLG_01778 4.8e-232 cypA C Cytochrome P450
HKLHMJLG_01779 6.4e-78 nucB M Deoxyribonuclease NucA/NucB
HKLHMJLG_01780 1.6e-118 yoaK S Membrane
HKLHMJLG_01781 1.1e-53 L COG2963 Transposase and inactivated derivatives
HKLHMJLG_01782 8.9e-133 L Molecular Function DNA binding, Biological Process DNA recombination
HKLHMJLG_01783 1.4e-62 ymzB
HKLHMJLG_01784 3.4e-255 aprX O Belongs to the peptidase S8 family
HKLHMJLG_01786 1.4e-127 ymaC S Replication protein
HKLHMJLG_01787 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
HKLHMJLG_01788 5.2e-54 ebrB P Small Multidrug Resistance protein
HKLHMJLG_01789 3.1e-48 ebrA P Small Multidrug Resistance protein
HKLHMJLG_01791 1.4e-47 ymaF S YmaF family
HKLHMJLG_01792 1.1e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKLHMJLG_01793 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HKLHMJLG_01794 2.5e-43
HKLHMJLG_01795 1.8e-20 ymzA
HKLHMJLG_01796 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HKLHMJLG_01797 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLHMJLG_01798 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLHMJLG_01799 2.4e-110 ymaB S MutT family
HKLHMJLG_01800 3.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKLHMJLG_01801 1.3e-176 spoVK O stage V sporulation protein K
HKLHMJLG_01802 2.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKLHMJLG_01803 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HKLHMJLG_01804 4.3e-68 glnR K transcriptional
HKLHMJLG_01805 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
HKLHMJLG_01806 2.8e-215 mrjp G Major royal jelly protein
HKLHMJLG_01807 9.6e-253 xynT G MFS/sugar transport protein
HKLHMJLG_01808 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HKLHMJLG_01809 3.2e-217 xylR GK ROK family
HKLHMJLG_01810 2.9e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HKLHMJLG_01811 4e-289 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
HKLHMJLG_01812 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HKLHMJLG_01818 5.4e-17
HKLHMJLG_01819 1.5e-22 dinB S DinB family
HKLHMJLG_01820 5.1e-23 dinB S DinB family
HKLHMJLG_01821 3.9e-187 adhP 1.1.1.1 C alcohol dehydrogenase
HKLHMJLG_01822 4.3e-146 yoaP 3.1.3.18 K YoaP-like
HKLHMJLG_01823 1.5e-100 J Acetyltransferase (GNAT) domain
HKLHMJLG_01824 1.6e-60
HKLHMJLG_01826 4.3e-120 ynaE S Domain of unknown function (DUF3885)
HKLHMJLG_01827 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKLHMJLG_01828 1.3e-116 AA10,CBM73 S Pfam:Chitin_bind_3
HKLHMJLG_01830 1.7e-14 yvgO
HKLHMJLG_01832 0.0 yobO M Pectate lyase superfamily protein
HKLHMJLG_01833 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HKLHMJLG_01834 1.1e-144 yndL S Replication protein
HKLHMJLG_01835 1.6e-07
HKLHMJLG_01836 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
HKLHMJLG_01837 5.4e-72 yndM S Protein of unknown function (DUF2512)
HKLHMJLG_01838 2.1e-12 yoaW
HKLHMJLG_01839 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKLHMJLG_01840 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HKLHMJLG_01841 3.5e-112 yneB L resolvase
HKLHMJLG_01842 9.8e-33 ynzC S UPF0291 protein
HKLHMJLG_01843 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKLHMJLG_01844 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
HKLHMJLG_01845 2.3e-28 yneF S UPF0154 protein
HKLHMJLG_01846 2.1e-23 ynzD S Spo0E like sporulation regulatory protein
HKLHMJLG_01847 3.9e-125 ccdA O cytochrome c biogenesis protein
HKLHMJLG_01848 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HKLHMJLG_01849 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HKLHMJLG_01850 8.5e-75 yneK S Protein of unknown function (DUF2621)
HKLHMJLG_01851 3.5e-61 hspX O Spore coat protein
HKLHMJLG_01852 2.3e-19 sspP S Belongs to the SspP family
HKLHMJLG_01853 7.5e-15 sspO S Belongs to the SspO family
HKLHMJLG_01854 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HKLHMJLG_01855 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKLHMJLG_01857 2.7e-33 tlp S Belongs to the Tlp family
HKLHMJLG_01858 4.1e-74 yneP S Thioesterase-like superfamily
HKLHMJLG_01859 4.4e-54 yneQ
HKLHMJLG_01860 1.3e-50 yneR S Belongs to the HesB IscA family
HKLHMJLG_01861 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKLHMJLG_01862 1.5e-68 yccU S CoA-binding protein
HKLHMJLG_01863 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKLHMJLG_01864 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKLHMJLG_01865 4.6e-13
HKLHMJLG_01866 5.1e-41 ynfC
HKLHMJLG_01867 2.2e-252 agcS E Sodium alanine symporter
HKLHMJLG_01868 3.6e-182 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HKLHMJLG_01869 1.8e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HKLHMJLG_01870 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HKLHMJLG_01871 1.8e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HKLHMJLG_01872 2e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMJLG_01873 5.4e-181 kdgR_1 K transcriptional
HKLHMJLG_01874 1.6e-222 exuT G Sugar (and other) transporter
HKLHMJLG_01875 6.8e-158 yndG S DoxX-like family
HKLHMJLG_01876 1.5e-77 yndH S Domain of unknown function (DUF4166)
HKLHMJLG_01877 8.3e-304 yndJ S YndJ-like protein
HKLHMJLG_01878 7e-85 S Protein of unknown function (DUF1430)
HKLHMJLG_01879 5.7e-64 V ABC transporter
HKLHMJLG_01881 1.4e-14
HKLHMJLG_01882 4.2e-214 S Platelet-activating factor acetylhydrolase, isoform II
HKLHMJLG_01883 7.3e-291 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HKLHMJLG_01884 4e-50 S Domain of unknown function (DUF4870)
HKLHMJLG_01885 2.4e-235 T PhoQ Sensor
HKLHMJLG_01886 3.4e-129 T Transcriptional regulatory protein, C terminal
HKLHMJLG_01887 1.1e-252 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
HKLHMJLG_01888 5.6e-294 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HKLHMJLG_01889 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_01890 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_01891 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_01892 2.6e-222 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKLHMJLG_01893 1.8e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HKLHMJLG_01894 7.1e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HKLHMJLG_01895 3.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKLHMJLG_01896 1.4e-254 yxjC EG COG2610 H gluconate symporter and related permeases
HKLHMJLG_01897 3.6e-224 bioI 1.14.14.46 C Cytochrome P450
HKLHMJLG_01898 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HKLHMJLG_01899 5.7e-129 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HKLHMJLG_01900 3e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HKLHMJLG_01901 2.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HKLHMJLG_01902 9.6e-146 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HKLHMJLG_01903 3.7e-72 yngA S membrane
HKLHMJLG_01904 3.8e-67 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKLHMJLG_01905 4.3e-43 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKLHMJLG_01906 3.2e-104 yngC S SNARE associated Golgi protein
HKLHMJLG_01907 8.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKLHMJLG_01908 1.3e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HKLHMJLG_01909 2.5e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HKLHMJLG_01910 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HKLHMJLG_01911 5.5e-253 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HKLHMJLG_01912 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKLHMJLG_01913 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HKLHMJLG_01914 2.3e-303 yngK T Glycosyl hydrolase-like 10
HKLHMJLG_01915 4.1e-65 yngL S Protein of unknown function (DUF1360)
HKLHMJLG_01916 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
HKLHMJLG_01917 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_01918 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_01919 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_01920 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_01921 3.7e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HKLHMJLG_01922 2.6e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
HKLHMJLG_01923 2.7e-247 yoeA V MATE efflux family protein
HKLHMJLG_01924 3.4e-97 yoeB S IseA DL-endopeptidase inhibitor
HKLHMJLG_01926 3.5e-97 L Integrase
HKLHMJLG_01927 1.8e-34 yoeD G Helix-turn-helix domain
HKLHMJLG_01928 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HKLHMJLG_01929 1.4e-199 ybcL EGP Major facilitator Superfamily
HKLHMJLG_01930 1.8e-50 ybzH K Helix-turn-helix domain
HKLHMJLG_01931 4.1e-270 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKLHMJLG_01932 3.1e-156 gltR1 K Transcriptional regulator
HKLHMJLG_01933 5.3e-189 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKLHMJLG_01934 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HKLHMJLG_01935 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HKLHMJLG_01936 5.1e-146 gltC K Transcriptional regulator
HKLHMJLG_01937 4.8e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKLHMJLG_01938 2.8e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKLHMJLG_01939 1e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HKLHMJLG_01940 1.4e-77 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
HKLHMJLG_01941 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMJLG_01942 2.1e-43 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKLHMJLG_01943 7.1e-141 yoxB
HKLHMJLG_01944 4.3e-193 yoaB EGP Major facilitator Superfamily
HKLHMJLG_01945 3.2e-275 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
HKLHMJLG_01946 1.9e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHMJLG_01947 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKLHMJLG_01948 4.9e-09 yoaF
HKLHMJLG_01950 1.5e-98 hpr K helix_turn_helix multiple antibiotic resistance protein
HKLHMJLG_01951 3.9e-44
HKLHMJLG_01952 2.6e-77 S SMI1-KNR4 cell-wall
HKLHMJLG_01953 8.2e-172 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKLHMJLG_01954 3e-99 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKLHMJLG_01955 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HKLHMJLG_01956 7.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
HKLHMJLG_01957 1.2e-92 yobS K Transcriptional regulator
HKLHMJLG_01958 1.3e-136 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HKLHMJLG_01959 1.8e-90 yobW
HKLHMJLG_01960 3.4e-55 czrA K transcriptional
HKLHMJLG_01961 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKLHMJLG_01962 2.8e-91 yozB S membrane
HKLHMJLG_01963 1.1e-141 yocB J Protein required for attachment to host cells
HKLHMJLG_01964 1.9e-94 yocC
HKLHMJLG_01965 3e-184 yocD 3.4.17.13 V peptidase S66
HKLHMJLG_01967 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
HKLHMJLG_01968 0.0 recQ 3.6.4.12 L DNA helicase
HKLHMJLG_01969 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKLHMJLG_01971 6.8e-60 dksA T general stress protein
HKLHMJLG_01972 7.8e-10 yocL
HKLHMJLG_01973 1.7e-08
HKLHMJLG_01974 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
HKLHMJLG_01975 3.8e-44 yozN
HKLHMJLG_01976 8.5e-37 yocN
HKLHMJLG_01977 2.4e-56 yozO S Bacterial PH domain
HKLHMJLG_01979 1.6e-31 yozC
HKLHMJLG_01980 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HKLHMJLG_01981 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HKLHMJLG_01982 1.4e-166 sodA 1.15.1.1 P Superoxide dismutase
HKLHMJLG_01983 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKLHMJLG_01984 2.1e-161 yocS S -transporter
HKLHMJLG_01985 2.4e-141 S Metallo-beta-lactamase superfamily
HKLHMJLG_01986 1.9e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HKLHMJLG_01987 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HKLHMJLG_01988 0.0 yojO P Von Willebrand factor
HKLHMJLG_01989 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
HKLHMJLG_01990 5.9e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKLHMJLG_01991 1.8e-226 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKLHMJLG_01992 1.1e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HKLHMJLG_01993 7.4e-112 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKLHMJLG_01995 4.7e-244 norM V Multidrug efflux pump
HKLHMJLG_01996 6.5e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKLHMJLG_01997 2.5e-126 yojG S deacetylase
HKLHMJLG_01998 9.7e-61 yojF S Protein of unknown function (DUF1806)
HKLHMJLG_01999 4.9e-23
HKLHMJLG_02000 1.7e-162 rarD S -transporter
HKLHMJLG_02001 1.3e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
HKLHMJLG_02003 2e-67 yodA S tautomerase
HKLHMJLG_02004 1.4e-62 yoaQ S Evidence 4 Homologs of previously reported genes of
HKLHMJLG_02005 1.4e-56 yodB K transcriptional
HKLHMJLG_02006 2.3e-105 yodC C nitroreductase
HKLHMJLG_02007 2.8e-108 mhqD S Carboxylesterase
HKLHMJLG_02008 1.5e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
HKLHMJLG_02009 1.4e-19 S Protein of unknown function (DUF3311)
HKLHMJLG_02010 2e-264 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKLHMJLG_02011 5.6e-275 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
HKLHMJLG_02012 2.8e-287 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLHMJLG_02013 2.6e-132 yydK K Transcriptional regulator
HKLHMJLG_02014 6.1e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HKLHMJLG_02015 2.8e-128 yodH Q Methyltransferase
HKLHMJLG_02016 1.1e-34 yodI
HKLHMJLG_02017 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HKLHMJLG_02018 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HKLHMJLG_02020 3.3e-55 yodL S YodL-like
HKLHMJLG_02021 1.6e-103 yodM 3.6.1.27 I Acid phosphatase homologues
HKLHMJLG_02022 6.2e-24 yozD S YozD-like protein
HKLHMJLG_02024 4.9e-125 yodN
HKLHMJLG_02025 4.1e-36 yozE S Belongs to the UPF0346 family
HKLHMJLG_02026 8.3e-47 yokU S YokU-like protein, putative antitoxin
HKLHMJLG_02027 7.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
HKLHMJLG_02028 6.6e-159 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HKLHMJLG_02029 1.5e-255 yodQ 3.5.1.16 E Acetylornithine deacetylase
HKLHMJLG_02030 6.1e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HKLHMJLG_02031 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKLHMJLG_02032 6.8e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKLHMJLG_02033 1.1e-52 yosT L Bacterial transcription activator, effector binding domain
HKLHMJLG_02035 9.8e-146 yiiD K acetyltransferase
HKLHMJLG_02036 3.2e-247 cgeD M maturation of the outermost layer of the spore
HKLHMJLG_02037 1.1e-41 cgeC
HKLHMJLG_02038 2.7e-52 cgeA
HKLHMJLG_02039 5.2e-181 cgeB S Spore maturation protein
HKLHMJLG_02040 8.9e-220 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HKLHMJLG_02041 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
HKLHMJLG_02048 1.9e-17 yoqH M LysM domain
HKLHMJLG_02049 3.6e-17 yoqH M LysM domain
HKLHMJLG_02050 1e-199 S aspartate phosphatase
HKLHMJLG_02052 7.4e-10 gabD_2 1.2.1.9 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKLHMJLG_02053 5.7e-63
HKLHMJLG_02054 3e-62 S SMI1-KNR4 cell-wall
HKLHMJLG_02055 4.5e-279 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKLHMJLG_02056 3.3e-84 G SMI1-KNR4 cell-wall
HKLHMJLG_02057 5.8e-76 yokF 3.1.31.1 L RNA catabolic process
HKLHMJLG_02058 8.1e-307 yokA L Recombinase
HKLHMJLG_02059 2.3e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
HKLHMJLG_02060 3.6e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HKLHMJLG_02061 2.7e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKLHMJLG_02062 1.4e-66 ypoP K transcriptional
HKLHMJLG_02063 5.5e-98 ypmS S protein conserved in bacteria
HKLHMJLG_02064 8.9e-136 ypmR E GDSL-like Lipase/Acylhydrolase
HKLHMJLG_02065 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HKLHMJLG_02066 2.6e-39 ypmP S Protein of unknown function (DUF2535)
HKLHMJLG_02067 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HKLHMJLG_02068 1.2e-180 pspF K Transcriptional regulator
HKLHMJLG_02069 9.3e-110 hlyIII S protein, Hemolysin III
HKLHMJLG_02070 4.2e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HKLHMJLG_02071 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKLHMJLG_02072 5.6e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKLHMJLG_02073 1e-113 ypjP S YpjP-like protein
HKLHMJLG_02074 5.2e-131 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HKLHMJLG_02075 2.3e-75 yphP S Belongs to the UPF0403 family
HKLHMJLG_02076 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HKLHMJLG_02077 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
HKLHMJLG_02078 6.3e-100 ypgQ S phosphohydrolase
HKLHMJLG_02079 1.1e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HKLHMJLG_02080 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKLHMJLG_02081 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HKLHMJLG_02082 1e-30 cspD K Cold-shock protein
HKLHMJLG_02083 3.3e-12 degR
HKLHMJLG_02084 1.2e-36 S Protein of unknown function (DUF2564)
HKLHMJLG_02085 5.7e-28 ypeQ S Zinc-finger
HKLHMJLG_02086 1e-122 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HKLHMJLG_02087 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HKLHMJLG_02088 1.7e-66 rnhA 3.1.26.4 L Ribonuclease
HKLHMJLG_02090 3.1e-164 polA 2.7.7.7 L 5'3' exonuclease
HKLHMJLG_02092 3.5e-39 ypbS S Protein of unknown function (DUF2533)
HKLHMJLG_02093 0.0 ypbR S Dynamin family
HKLHMJLG_02094 7.2e-89 ypbQ S protein conserved in bacteria
HKLHMJLG_02095 3.5e-205 bcsA Q Naringenin-chalcone synthase
HKLHMJLG_02096 1.1e-107 J Acetyltransferase (GNAT) domain
HKLHMJLG_02097 6.2e-51 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HKLHMJLG_02099 3.7e-97 ydfR S Protein of unknown function (DUF421)
HKLHMJLG_02100 4.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
HKLHMJLG_02102 8.9e-159 pbuX F xanthine
HKLHMJLG_02104 3.2e-90 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKLHMJLG_02105 1.7e-08 K Cro/C1-type HTH DNA-binding domain
HKLHMJLG_02107 3.4e-24 S Macro domain
HKLHMJLG_02112 4.9e-23 sspB S spore protein
HKLHMJLG_02121 6.4e-29 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKLHMJLG_02122 1.1e-150 S Thymidylate synthase
HKLHMJLG_02123 1e-49 S Protein of unknown function (DUF1643)
HKLHMJLG_02127 2.7e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HKLHMJLG_02128 4.8e-27 O Glutaredoxin
HKLHMJLG_02129 9.4e-26
HKLHMJLG_02130 6.9e-47 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLHMJLG_02131 2.5e-89 L HNH endonuclease
HKLHMJLG_02132 7.4e-101 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLHMJLG_02134 3.3e-172 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLHMJLG_02135 1.4e-196 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
HKLHMJLG_02136 8.1e-56 S NrdI Flavodoxin like
HKLHMJLG_02140 2e-12 larC 4.99.1.12 FJ Protein conserved in bacteria
HKLHMJLG_02149 5.1e-24 S hydrolase activity
HKLHMJLG_02151 2.2e-09
HKLHMJLG_02156 1.2e-88 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HKLHMJLG_02157 2.5e-70 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
HKLHMJLG_02160 2.3e-23 DR0488 S protein conserved in bacteria
HKLHMJLG_02161 0.0 S Bacterial DNA polymerase III alpha subunit
HKLHMJLG_02162 1.5e-271 recJ L Single-stranded-DNA-specific exonuclease RecJ
HKLHMJLG_02163 1.8e-204 L DNA primase activity
HKLHMJLG_02164 1.5e-211 3.6.4.12 J DnaB-like helicase C terminal domain
HKLHMJLG_02165 5.6e-80
HKLHMJLG_02166 9e-173 L AAA domain
HKLHMJLG_02167 1.6e-155
HKLHMJLG_02173 6.7e-219 M Parallel beta-helix repeats
HKLHMJLG_02174 1.6e-82 S Pfam:DUF867
HKLHMJLG_02177 2.5e-161
HKLHMJLG_02179 7e-124 yoqW S Belongs to the SOS response-associated peptidase family
HKLHMJLG_02180 2.4e-139 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HKLHMJLG_02183 4.5e-61 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
HKLHMJLG_02185 5.2e-74
HKLHMJLG_02190 2.9e-93 S Protein of unknown function (DUF1273)
HKLHMJLG_02195 4.1e-64
HKLHMJLG_02202 1.3e-22
HKLHMJLG_02204 4.9e-11 S YopX protein
HKLHMJLG_02206 2.6e-63 S dUTPase
HKLHMJLG_02210 1.6e-13 K Transcriptional regulator
HKLHMJLG_02211 5.2e-35
HKLHMJLG_02212 4.6e-191
HKLHMJLG_02213 1.6e-37 L Belongs to the 'phage' integrase family
HKLHMJLG_02219 2.4e-79
HKLHMJLG_02232 8e-23 K Cro/C1-type HTH DNA-binding domain
HKLHMJLG_02233 1.4e-69 yoaW
HKLHMJLG_02234 1.6e-21 I Acyltransferase family
HKLHMJLG_02240 6.6e-197 3.1.21.3 L Domain of unknown function (DUF4942)
HKLHMJLG_02242 6.3e-155
HKLHMJLG_02245 4.5e-59 ftsZ D Tubulin/FtsZ family, GTPase domain
HKLHMJLG_02249 0.0
HKLHMJLG_02250 5.5e-15 L GIY-YIG type nucleases (URI domain)
HKLHMJLG_02251 8.9e-81
HKLHMJLG_02252 1.4e-33 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKLHMJLG_02254 1.3e-07
HKLHMJLG_02257 6.6e-218 S Calcineurin-like phosphoesterase superfamily domain
HKLHMJLG_02260 3.5e-18
HKLHMJLG_02261 6.7e-110
HKLHMJLG_02262 1.1e-18
HKLHMJLG_02263 5.3e-39
HKLHMJLG_02265 6.8e-68
HKLHMJLG_02268 6.8e-55
HKLHMJLG_02269 2.2e-85
HKLHMJLG_02270 1.9e-98
HKLHMJLG_02271 1.7e-57
HKLHMJLG_02273 3.9e-49
HKLHMJLG_02274 1.5e-48 S Domain of unknown function (DUF2479)
HKLHMJLG_02275 2.1e-13
HKLHMJLG_02276 1.9e-81 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
HKLHMJLG_02277 1.6e-58
HKLHMJLG_02278 2.5e-47
HKLHMJLG_02279 2.4e-173 xerH A Belongs to the 'phage' integrase family
HKLHMJLG_02282 1.2e-75
HKLHMJLG_02283 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKLHMJLG_02284 5.5e-85 S Phage tail protein
HKLHMJLG_02285 5.5e-198 S Pfam Transposase IS66
HKLHMJLG_02286 2.6e-93
HKLHMJLG_02287 2.5e-214 M Pectate lyase superfamily protein
HKLHMJLG_02288 1.4e-75 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HKLHMJLG_02290 3.1e-32 S Bacteriophage holin
HKLHMJLG_02293 4.3e-89 S response regulator aspartate phosphatase
HKLHMJLG_02295 1.2e-222 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLHMJLG_02296 1.4e-40 S YolD-like protein
HKLHMJLG_02297 4.8e-129 yunB S Sporulation protein YunB (Spo_YunB)
HKLHMJLG_02299 1e-99 yokK S SMI1 / KNR4 family
HKLHMJLG_02300 1.8e-216 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKLHMJLG_02301 1.3e-166 V HNH endonuclease
HKLHMJLG_02302 1.5e-92 G SMI1-KNR4 cell-wall
HKLHMJLG_02303 8.3e-78 yokF 3.1.31.1 L RNA catabolic process
HKLHMJLG_02304 3.1e-50 L Recombinase
HKLHMJLG_02305 6.4e-64 pbuX F xanthine
HKLHMJLG_02306 3.3e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKLHMJLG_02307 3.8e-295 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HKLHMJLG_02308 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HKLHMJLG_02310 6.6e-22 S YpzG-like protein
HKLHMJLG_02311 1.9e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HKLHMJLG_02312 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKLHMJLG_02313 8.3e-99 ypsA S Belongs to the UPF0398 family
HKLHMJLG_02314 9.9e-33 cotD S Inner spore coat protein D
HKLHMJLG_02315 5.6e-236 yprB L RNase_H superfamily
HKLHMJLG_02316 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HKLHMJLG_02317 6.1e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HKLHMJLG_02318 1.7e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HKLHMJLG_02319 1.5e-50 yppG S YppG-like protein
HKLHMJLG_02321 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
HKLHMJLG_02324 5.7e-188 yppC S Protein of unknown function (DUF2515)
HKLHMJLG_02325 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKLHMJLG_02326 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKLHMJLG_02327 2.8e-90 ypoC
HKLHMJLG_02328 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKLHMJLG_02329 3e-130 dnaD L DNA replication protein DnaD
HKLHMJLG_02330 2e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HKLHMJLG_02331 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HKLHMJLG_02332 4e-81 ypmB S protein conserved in bacteria
HKLHMJLG_02333 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HKLHMJLG_02334 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HKLHMJLG_02335 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HKLHMJLG_02336 5e-159 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HKLHMJLG_02337 6.3e-151 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HKLHMJLG_02338 1.6e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKLHMJLG_02339 1.2e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKLHMJLG_02340 1.8e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HKLHMJLG_02341 1.3e-131 bshB1 S proteins, LmbE homologs
HKLHMJLG_02342 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HKLHMJLG_02343 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKLHMJLG_02344 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HKLHMJLG_02345 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HKLHMJLG_02346 1e-226 oxdC 4.1.1.2 G Oxalate decarboxylase
HKLHMJLG_02347 5.1e-142 ypjB S sporulation protein
HKLHMJLG_02348 4.1e-104 ypjA S membrane
HKLHMJLG_02349 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HKLHMJLG_02350 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HKLHMJLG_02351 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HKLHMJLG_02352 8.5e-78 ypiF S Protein of unknown function (DUF2487)
HKLHMJLG_02353 6.2e-99 ypiB S Belongs to the UPF0302 family
HKLHMJLG_02354 2.2e-232 S COG0457 FOG TPR repeat
HKLHMJLG_02355 1.2e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKLHMJLG_02356 5e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HKLHMJLG_02357 3.2e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKLHMJLG_02358 2.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKLHMJLG_02359 1.7e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKLHMJLG_02360 2.4e-121 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HKLHMJLG_02361 2e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HKLHMJLG_02362 4.1e-160 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKLHMJLG_02363 2.5e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKLHMJLG_02364 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HKLHMJLG_02365 2.5e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKLHMJLG_02366 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKLHMJLG_02367 8.5e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HKLHMJLG_02368 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HKLHMJLG_02369 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKLHMJLG_02370 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKLHMJLG_02371 1.6e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HKLHMJLG_02372 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HKLHMJLG_02373 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
HKLHMJLG_02374 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKLHMJLG_02375 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HKLHMJLG_02376 3.6e-134 yphF
HKLHMJLG_02377 2.5e-16 yphE S Protein of unknown function (DUF2768)
HKLHMJLG_02378 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HKLHMJLG_02379 2.1e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HKLHMJLG_02380 1.1e-104 yphA
HKLHMJLG_02381 4.7e-08 S YpzI-like protein
HKLHMJLG_02382 1.3e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKLHMJLG_02383 5.6e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HKLHMJLG_02384 2.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HKLHMJLG_02385 1.4e-12 S Family of unknown function (DUF5359)
HKLHMJLG_02386 2.2e-61 ypfA M Flagellar protein YcgR
HKLHMJLG_02387 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HKLHMJLG_02388 4.9e-162 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HKLHMJLG_02389 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
HKLHMJLG_02390 9e-189 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HKLHMJLG_02391 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKLHMJLG_02392 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HKLHMJLG_02393 2.8e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
HKLHMJLG_02394 5.7e-85 ypbF S Protein of unknown function (DUF2663)
HKLHMJLG_02395 1.6e-79 ypbE M Lysin motif
HKLHMJLG_02396 1.3e-99 ypbD S metal-dependent membrane protease
HKLHMJLG_02397 1.7e-273 recQ 3.6.4.12 L DNA helicase
HKLHMJLG_02398 2.8e-196 ypbB 5.1.3.1 S protein conserved in bacteria
HKLHMJLG_02399 3.6e-41 fer C Ferredoxin
HKLHMJLG_02400 9.2e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKLHMJLG_02401 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHMJLG_02402 4.2e-195 rsiX
HKLHMJLG_02403 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HKLHMJLG_02404 0.0 resE 2.7.13.3 T Histidine kinase
HKLHMJLG_02405 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_02406 1.2e-192 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HKLHMJLG_02407 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HKLHMJLG_02408 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HKLHMJLG_02409 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKLHMJLG_02410 2.2e-88 spmB S Spore maturation protein
HKLHMJLG_02411 2e-103 spmA S Spore maturation protein
HKLHMJLG_02412 2.3e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HKLHMJLG_02413 2.9e-93 ypuI S Protein of unknown function (DUF3907)
HKLHMJLG_02414 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKLHMJLG_02415 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKLHMJLG_02417 3.8e-93 ypuF S Domain of unknown function (DUF309)
HKLHMJLG_02418 1.3e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKLHMJLG_02419 3.3e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKLHMJLG_02420 8.3e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKLHMJLG_02421 1e-111 ribE 2.5.1.9 H Riboflavin synthase
HKLHMJLG_02422 7.3e-211 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKLHMJLG_02423 1.7e-49 ypuD
HKLHMJLG_02424 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKLHMJLG_02425 3.1e-81 ccdC1 O Protein of unknown function (DUF1453)
HKLHMJLG_02426 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKLHMJLG_02427 5.4e-156 ypuA S Secreted protein
HKLHMJLG_02428 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKLHMJLG_02429 7.1e-270 spoVAF EG Stage V sporulation protein AF
HKLHMJLG_02430 1.8e-110 spoVAEA S stage V sporulation protein
HKLHMJLG_02431 3.8e-57 spoVAEB S stage V sporulation protein
HKLHMJLG_02432 1.4e-189 spoVAD I Stage V sporulation protein AD
HKLHMJLG_02433 1.3e-78 spoVAC S stage V sporulation protein AC
HKLHMJLG_02434 3.9e-60 spoVAB S Stage V sporulation protein AB
HKLHMJLG_02435 3.7e-111 spoVAA S Stage V sporulation protein AA
HKLHMJLG_02436 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKLHMJLG_02437 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HKLHMJLG_02438 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HKLHMJLG_02439 3.1e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HKLHMJLG_02440 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HKLHMJLG_02441 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKLHMJLG_02442 3.7e-165 xerD L recombinase XerD
HKLHMJLG_02443 5.4e-36 S Protein of unknown function (DUF4227)
HKLHMJLG_02444 1.9e-80 fur P Belongs to the Fur family
HKLHMJLG_02445 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HKLHMJLG_02446 6.6e-34 yqkK
HKLHMJLG_02447 5.7e-22
HKLHMJLG_02448 2.2e-243 mleA 1.1.1.38 C malic enzyme
HKLHMJLG_02449 1.6e-242 mleN C Na H antiporter
HKLHMJLG_02450 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HKLHMJLG_02451 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
HKLHMJLG_02452 7.8e-58 ansR K Transcriptional regulator
HKLHMJLG_02453 1.1e-222 yqxK 3.6.4.12 L DNA helicase
HKLHMJLG_02454 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HKLHMJLG_02456 1.7e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HKLHMJLG_02458 5.7e-177 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HKLHMJLG_02459 3.2e-39 yqkC S Protein of unknown function (DUF2552)
HKLHMJLG_02460 7.7e-61 yqkB S Belongs to the HesB IscA family
HKLHMJLG_02461 2.3e-176 yqkA K GrpB protein
HKLHMJLG_02462 4.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HKLHMJLG_02463 3.9e-89 yqjY K acetyltransferase
HKLHMJLG_02464 7.2e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLHMJLG_02465 4.4e-58 S YolD-like protein
HKLHMJLG_02467 1.8e-190 yueF S transporter activity
HKLHMJLG_02469 3.6e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKLHMJLG_02470 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HKLHMJLG_02471 1.3e-257 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HKLHMJLG_02472 1.3e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMJLG_02473 6.6e-176 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HKLHMJLG_02474 2.1e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKLHMJLG_02475 1.1e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HKLHMJLG_02476 6.4e-240 pksG 2.3.3.10 I synthase
HKLHMJLG_02477 1.7e-218 eryK 1.14.13.154 C Cytochrome P450
HKLHMJLG_02478 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKLHMJLG_02479 0.0 Q Polyketide synthase of type I
HKLHMJLG_02480 0.0 pfaA Q Polyketide synthase of type I
HKLHMJLG_02481 0.0 pksJ Q Polyketide synthase of type I
HKLHMJLG_02482 0.0 Q Polyketide synthase of type I
HKLHMJLG_02483 0.0 1.1.1.320 Q Polyketide synthase of type I
HKLHMJLG_02484 0.0 pksJ Q Polyketide synthase of type I
HKLHMJLG_02485 1.8e-128 IQ reductase
HKLHMJLG_02486 3.5e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKLHMJLG_02489 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKLHMJLG_02490 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
HKLHMJLG_02491 2.6e-163 K LysR substrate binding domain
HKLHMJLG_02492 3.2e-50 S GlpM protein
HKLHMJLG_02493 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HKLHMJLG_02494 1e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKLHMJLG_02495 1.5e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKLHMJLG_02496 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKLHMJLG_02497 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKLHMJLG_02498 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLHMJLG_02499 2.4e-25 yqzJ
HKLHMJLG_02500 7.8e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKLHMJLG_02501 8.1e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HKLHMJLG_02502 8.8e-292 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKLHMJLG_02503 1.1e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HKLHMJLG_02505 4.8e-96 yqjB S protein conserved in bacteria
HKLHMJLG_02506 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
HKLHMJLG_02507 6.5e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKLHMJLG_02508 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
HKLHMJLG_02509 9e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
HKLHMJLG_02510 1e-75 yqiW S Belongs to the UPF0403 family
HKLHMJLG_02511 1.2e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKLHMJLG_02512 8.8e-205 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKLHMJLG_02513 3e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKLHMJLG_02514 3e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKLHMJLG_02515 3.1e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKLHMJLG_02516 7.5e-208 buk 2.7.2.7 C Belongs to the acetokinase family
HKLHMJLG_02517 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKLHMJLG_02518 9.5e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HKLHMJLG_02519 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HKLHMJLG_02520 3.2e-34 yqzF S Protein of unknown function (DUF2627)
HKLHMJLG_02521 1.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HKLHMJLG_02522 3.4e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HKLHMJLG_02523 6.3e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HKLHMJLG_02524 1.8e-204 mmgC I acyl-CoA dehydrogenase
HKLHMJLG_02525 3.7e-154 hbdA 1.1.1.157 I Dehydrogenase
HKLHMJLG_02526 5.7e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
HKLHMJLG_02527 5.6e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKLHMJLG_02528 5.2e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HKLHMJLG_02529 2.5e-17
HKLHMJLG_02530 1.5e-101 ytaF P Probably functions as a manganese efflux pump
HKLHMJLG_02531 1.8e-113 K Protein of unknown function (DUF1232)
HKLHMJLG_02533 1.4e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HKLHMJLG_02536 2.7e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKLHMJLG_02537 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HKLHMJLG_02538 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
HKLHMJLG_02539 1.2e-305 recN L May be involved in recombinational repair of damaged DNA
HKLHMJLG_02540 3.9e-78 argR K Regulates arginine biosynthesis genes
HKLHMJLG_02541 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HKLHMJLG_02542 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKLHMJLG_02543 2.8e-48 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKLHMJLG_02544 7.8e-27 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKLHMJLG_02545 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKLHMJLG_02546 1.4e-60 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKLHMJLG_02547 3.5e-46 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKLHMJLG_02548 9.5e-112 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKLHMJLG_02549 9.8e-20 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKLHMJLG_02550 7.5e-46 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKLHMJLG_02551 1.9e-11 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKLHMJLG_02552 8.1e-67 yqhY S protein conserved in bacteria
HKLHMJLG_02553 1.9e-13 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HKLHMJLG_02554 2.9e-69 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HKLHMJLG_02555 5.9e-129 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HKLHMJLG_02556 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKLHMJLG_02557 5.6e-62 spoIIIAH S SpoIIIAH-like protein
HKLHMJLG_02558 3.4e-118 spoIIIAG S stage III sporulation protein AG
HKLHMJLG_02559 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HKLHMJLG_02560 1.1e-199 spoIIIAE S stage III sporulation protein AE
HKLHMJLG_02561 2.5e-41 spoIIIAD S Stage III sporulation protein AD
HKLHMJLG_02562 7.6e-29 spoIIIAC S stage III sporulation protein AC
HKLHMJLG_02563 1.7e-85 spoIIIAB S Stage III sporulation protein
HKLHMJLG_02564 4.2e-172 spoIIIAA S stage III sporulation protein AA
HKLHMJLG_02565 1.8e-36 yqhV S Protein of unknown function (DUF2619)
HKLHMJLG_02566 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKLHMJLG_02567 3.2e-171 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HKLHMJLG_02568 3.7e-88 yqhR S Conserved membrane protein YqhR
HKLHMJLG_02569 8e-174 yqhQ S Protein of unknown function (DUF1385)
HKLHMJLG_02570 1.3e-61 yqhP
HKLHMJLG_02571 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
HKLHMJLG_02572 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HKLHMJLG_02573 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HKLHMJLG_02574 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
HKLHMJLG_02575 2.4e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKLHMJLG_02576 2.1e-252 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKLHMJLG_02577 2.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HKLHMJLG_02578 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HKLHMJLG_02579 8.4e-153 yqhG S Bacterial protein YqhG of unknown function
HKLHMJLG_02580 5.2e-23 sinI S Anti-repressor SinI
HKLHMJLG_02581 7.8e-55 sinR K transcriptional
HKLHMJLG_02582 3.3e-141 tasA S Cell division protein FtsN
HKLHMJLG_02583 8.9e-67 sipW 3.4.21.89 U Signal peptidase
HKLHMJLG_02584 1.4e-121 yqxM
HKLHMJLG_02585 1.3e-54 yqzG S Protein of unknown function (DUF3889)
HKLHMJLG_02586 2.3e-26 yqzE S YqzE-like protein
HKLHMJLG_02587 7.8e-64 S ComG operon protein 7
HKLHMJLG_02588 5.6e-68 comGF U Putative Competence protein ComGF
HKLHMJLG_02589 5.8e-20 comGE
HKLHMJLG_02590 1.6e-73 gspH NU Tfp pilus assembly protein FimT
HKLHMJLG_02591 8.9e-50 comGC U Required for transformation and DNA binding
HKLHMJLG_02592 6.6e-182 comGB NU COG1459 Type II secretory pathway, component PulF
HKLHMJLG_02593 6.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKLHMJLG_02594 4.1e-186 corA P Mg2 transporter protein
HKLHMJLG_02595 3.3e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKLHMJLG_02596 1.6e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKLHMJLG_02598 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
HKLHMJLG_02599 3.1e-37 yqgY S Protein of unknown function (DUF2626)
HKLHMJLG_02600 8.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HKLHMJLG_02601 5.4e-20 yqgW S Protein of unknown function (DUF2759)
HKLHMJLG_02602 6.9e-50 yqgV S Thiamine-binding protein
HKLHMJLG_02603 9.2e-200 yqgU
HKLHMJLG_02604 1.7e-223 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HKLHMJLG_02605 4.9e-179 glcK 2.7.1.2 G Glucokinase
HKLHMJLG_02606 1e-28 yqgQ S Protein conserved in bacteria
HKLHMJLG_02607 6.1e-214 nhaC C Na H antiporter
HKLHMJLG_02608 4e-07 yqgO
HKLHMJLG_02609 4.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKLHMJLG_02610 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKLHMJLG_02611 1.2e-50 yqzD
HKLHMJLG_02612 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKLHMJLG_02613 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKLHMJLG_02614 3.3e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKLHMJLG_02615 4.1e-156 pstA P Phosphate transport system permease
HKLHMJLG_02616 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HKLHMJLG_02617 1.7e-157 pstS P Phosphate
HKLHMJLG_02618 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HKLHMJLG_02619 2e-228 yqgE EGP Major facilitator superfamily
HKLHMJLG_02620 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HKLHMJLG_02621 3e-76 yqgC S protein conserved in bacteria
HKLHMJLG_02622 8.7e-131 yqgB S Protein of unknown function (DUF1189)
HKLHMJLG_02623 3.7e-48 yqfZ M LysM domain
HKLHMJLG_02624 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKLHMJLG_02625 2.3e-52 yqfX S membrane
HKLHMJLG_02626 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HKLHMJLG_02627 2.9e-72 zur P Belongs to the Fur family
HKLHMJLG_02628 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HKLHMJLG_02629 9.3e-37 yqfT S Protein of unknown function (DUF2624)
HKLHMJLG_02630 2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKLHMJLG_02631 1.2e-247 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKLHMJLG_02632 3.5e-49 yqfQ S YqfQ-like protein
HKLHMJLG_02633 1.7e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HKLHMJLG_02634 2.5e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKLHMJLG_02635 6.4e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HKLHMJLG_02636 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
HKLHMJLG_02637 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKLHMJLG_02638 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKLHMJLG_02639 6.1e-88 yaiI S Belongs to the UPF0178 family
HKLHMJLG_02640 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKLHMJLG_02641 4.5e-112 ccpN K CBS domain
HKLHMJLG_02642 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HKLHMJLG_02643 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HKLHMJLG_02644 4.1e-144 recO L Involved in DNA repair and RecF pathway recombination
HKLHMJLG_02645 1.8e-16 S YqzL-like protein
HKLHMJLG_02646 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKLHMJLG_02647 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKLHMJLG_02648 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HKLHMJLG_02649 2.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKLHMJLG_02650 0.0 yqfF S membrane-associated HD superfamily hydrolase
HKLHMJLG_02651 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
HKLHMJLG_02652 4.2e-217 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HKLHMJLG_02653 9.3e-46 yqfC S sporulation protein YqfC
HKLHMJLG_02654 9.9e-55 yqfB
HKLHMJLG_02655 1.6e-121 yqfA S UPF0365 protein
HKLHMJLG_02656 5.7e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HKLHMJLG_02657 1.2e-68 yqeY S Yqey-like protein
HKLHMJLG_02658 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HKLHMJLG_02659 4.6e-158 yqeW P COG1283 Na phosphate symporter
HKLHMJLG_02660 1.2e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HKLHMJLG_02661 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKLHMJLG_02662 1.6e-174 prmA J Methylates ribosomal protein L11
HKLHMJLG_02663 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKLHMJLG_02664 0.0 dnaK O Heat shock 70 kDa protein
HKLHMJLG_02665 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKLHMJLG_02666 2.3e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKLHMJLG_02667 6.3e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
HKLHMJLG_02668 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKLHMJLG_02669 3.8e-54 yqxA S Protein of unknown function (DUF3679)
HKLHMJLG_02670 1.4e-220 spoIIP M stage II sporulation protein P
HKLHMJLG_02671 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HKLHMJLG_02672 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
HKLHMJLG_02673 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
HKLHMJLG_02674 0.0 comEC S Competence protein ComEC
HKLHMJLG_02675 8e-105 comEB 3.5.4.12 F ComE operon protein 2
HKLHMJLG_02676 2.5e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HKLHMJLG_02677 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKLHMJLG_02678 2.2e-139 yqeM Q Methyltransferase
HKLHMJLG_02679 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKLHMJLG_02680 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HKLHMJLG_02681 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKLHMJLG_02682 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HKLHMJLG_02683 1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKLHMJLG_02684 1.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HKLHMJLG_02685 2e-94 yqeG S hydrolase of the HAD superfamily
HKLHMJLG_02687 7.7e-140 yqeF E GDSL-like Lipase/Acylhydrolase
HKLHMJLG_02688 1.5e-140 3.5.1.104 G Polysaccharide deacetylase
HKLHMJLG_02689 4.2e-107 yqeD S SNARE associated Golgi protein
HKLHMJLG_02690 9.7e-40 2.3.1.57 K Acetyltransferase (GNAT) domain
HKLHMJLG_02691 1.9e-215 EGP Major facilitator Superfamily
HKLHMJLG_02692 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKLHMJLG_02693 1.6e-151 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HKLHMJLG_02694 5.5e-92 K Transcriptional regulator PadR-like family
HKLHMJLG_02695 2.4e-148 ydeE K AraC family transcriptional regulator
HKLHMJLG_02696 3.1e-98 adk 2.7.4.3 F adenylate kinase activity
HKLHMJLG_02697 1.7e-31 yyaR K acetyltransferase
HKLHMJLG_02698 4e-77 tetL EGP Major facilitator Superfamily
HKLHMJLG_02699 1.1e-81 yyaR K Acetyltransferase (GNAT) domain
HKLHMJLG_02700 4.7e-93 yrdA S DinB family
HKLHMJLG_02702 1e-145 S hydrolase
HKLHMJLG_02703 5.1e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HKLHMJLG_02704 1.2e-129 glvR K Helix-turn-helix domain, rpiR family
HKLHMJLG_02705 8.2e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKLHMJLG_02706 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HKLHMJLG_02707 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HKLHMJLG_02708 7.5e-82 romA S Beta-lactamase superfamily domain
HKLHMJLG_02709 5.6e-69 romA S Beta-lactamase superfamily domain
HKLHMJLG_02710 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKLHMJLG_02711 1.1e-164 yybE K Transcriptional regulator
HKLHMJLG_02712 3.8e-213 ynfM EGP Major facilitator Superfamily
HKLHMJLG_02713 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HKLHMJLG_02714 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HKLHMJLG_02715 3.9e-93 yrhH Q methyltransferase
HKLHMJLG_02717 8e-143 focA P Formate nitrite
HKLHMJLG_02718 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HKLHMJLG_02719 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HKLHMJLG_02720 7e-81 yrhD S Protein of unknown function (DUF1641)
HKLHMJLG_02721 4.6e-35 yrhC S YrhC-like protein
HKLHMJLG_02722 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKLHMJLG_02723 5.2e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HKLHMJLG_02724 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKLHMJLG_02725 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HKLHMJLG_02726 4.1e-27 yrzA S Protein of unknown function (DUF2536)
HKLHMJLG_02727 3.1e-69 yrrS S Protein of unknown function (DUF1510)
HKLHMJLG_02728 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HKLHMJLG_02729 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKLHMJLG_02730 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HKLHMJLG_02731 2.3e-245 yegQ O COG0826 Collagenase and related proteases
HKLHMJLG_02732 1.7e-173 yegQ O Peptidase U32
HKLHMJLG_02733 2.8e-117 yrrM 2.1.1.104 S O-methyltransferase
HKLHMJLG_02734 9.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKLHMJLG_02735 7.1e-46 yrzB S Belongs to the UPF0473 family
HKLHMJLG_02736 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKLHMJLG_02737 1.7e-41 yrzL S Belongs to the UPF0297 family
HKLHMJLG_02738 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKLHMJLG_02739 2.6e-165 yrrI S AI-2E family transporter
HKLHMJLG_02740 2.9e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKLHMJLG_02741 3.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
HKLHMJLG_02742 1.2e-109 gluC P ABC transporter
HKLHMJLG_02743 3.1e-108 glnP P ABC transporter
HKLHMJLG_02744 2.1e-08 S Protein of unknown function (DUF3918)
HKLHMJLG_02745 2.9e-30 yrzR
HKLHMJLG_02746 9.1e-83 yrrD S protein conserved in bacteria
HKLHMJLG_02747 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKLHMJLG_02748 1.7e-18 S COG0457 FOG TPR repeat
HKLHMJLG_02749 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKLHMJLG_02750 8.8e-212 iscS 2.8.1.7 E Cysteine desulfurase
HKLHMJLG_02751 7.8e-64 cymR K Transcriptional regulator
HKLHMJLG_02752 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HKLHMJLG_02753 1.1e-53 L COG2963 Transposase and inactivated derivatives
HKLHMJLG_02754 8.9e-133 L Molecular Function DNA binding, Biological Process DNA recombination
HKLHMJLG_02755 7.4e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HKLHMJLG_02756 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HKLHMJLG_02757 8.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HKLHMJLG_02760 1.5e-278 lytH 3.5.1.28 M COG3103 SH3 domain protein
HKLHMJLG_02761 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKLHMJLG_02762 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKLHMJLG_02763 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKLHMJLG_02764 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HKLHMJLG_02765 5.7e-47 yrvD S Lipopolysaccharide assembly protein A domain
HKLHMJLG_02766 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HKLHMJLG_02767 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKLHMJLG_02768 1.6e-48 yrzD S Post-transcriptional regulator
HKLHMJLG_02769 9.4e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKLHMJLG_02770 9.5e-110 yrbG S membrane
HKLHMJLG_02771 2.4e-60 yrzE S Protein of unknown function (DUF3792)
HKLHMJLG_02772 5.6e-37 yajC U Preprotein translocase subunit YajC
HKLHMJLG_02773 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKLHMJLG_02774 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKLHMJLG_02775 1.4e-19 yrzS S Protein of unknown function (DUF2905)
HKLHMJLG_02776 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKLHMJLG_02777 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKLHMJLG_02778 4.1e-92 bofC S BofC C-terminal domain
HKLHMJLG_02780 1.2e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKLHMJLG_02781 6.8e-146 safA M spore coat assembly protein SafA
HKLHMJLG_02782 5.9e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HKLHMJLG_02783 6.5e-151 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HKLHMJLG_02784 2.1e-301 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HKLHMJLG_02785 6.6e-223 nifS 2.8.1.7 E Cysteine desulfurase
HKLHMJLG_02786 1.3e-91 niaR S small molecule binding protein (contains 3H domain)
HKLHMJLG_02787 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
HKLHMJLG_02788 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HKLHMJLG_02789 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKLHMJLG_02790 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HKLHMJLG_02791 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HKLHMJLG_02792 3.2e-56 ysxB J ribosomal protein
HKLHMJLG_02793 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HKLHMJLG_02794 1.2e-160 spoIVFB S Stage IV sporulation protein
HKLHMJLG_02795 5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HKLHMJLG_02796 8e-143 minD D Belongs to the ParA family
HKLHMJLG_02797 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKLHMJLG_02798 1.4e-84 mreD M shape-determining protein
HKLHMJLG_02799 1.2e-157 mreC M Involved in formation and maintenance of cell shape
HKLHMJLG_02800 4e-184 mreB D Rod shape-determining protein MreB
HKLHMJLG_02801 1.8e-127 radC E Belongs to the UPF0758 family
HKLHMJLG_02802 1.2e-100 maf D septum formation protein Maf
HKLHMJLG_02803 2.5e-138 spoIIB S Sporulation related domain
HKLHMJLG_02804 3.5e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HKLHMJLG_02805 5.1e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKLHMJLG_02806 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKLHMJLG_02807 2.1e-25
HKLHMJLG_02808 5.6e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HKLHMJLG_02809 1.5e-227 spoVID M stage VI sporulation protein D
HKLHMJLG_02810 2.3e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HKLHMJLG_02811 1e-184 hemB 4.2.1.24 H Belongs to the ALAD family
HKLHMJLG_02812 5e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HKLHMJLG_02813 3.9e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HKLHMJLG_02814 3.6e-146 hemX O cytochrome C
HKLHMJLG_02815 2.4e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HKLHMJLG_02816 1.3e-87 ysxD
HKLHMJLG_02817 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HKLHMJLG_02818 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HKLHMJLG_02819 2.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HKLHMJLG_02820 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKLHMJLG_02821 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKLHMJLG_02822 2.4e-189 ysoA H Tetratricopeptide repeat
HKLHMJLG_02823 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKLHMJLG_02824 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKLHMJLG_02825 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKLHMJLG_02826 2.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKLHMJLG_02827 2e-191 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKLHMJLG_02828 5.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
HKLHMJLG_02829 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HKLHMJLG_02833 9.6e-148 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HKLHMJLG_02834 0.0 V Type I restriction-modification system methyltransferase subunit()
HKLHMJLG_02835 2.3e-61 L Phage integrase family
HKLHMJLG_02838 5.5e-89 ysnB S Phosphoesterase
HKLHMJLG_02839 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKLHMJLG_02840 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HKLHMJLG_02841 9e-198 gerM S COG5401 Spore germination protein
HKLHMJLG_02842 7.8e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKLHMJLG_02843 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HKLHMJLG_02844 2e-30 gerE K Transcriptional regulator
HKLHMJLG_02845 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HKLHMJLG_02846 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HKLHMJLG_02847 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HKLHMJLG_02848 4.8e-108 sdhC C succinate dehydrogenase
HKLHMJLG_02849 1.2e-79 yslB S Protein of unknown function (DUF2507)
HKLHMJLG_02850 1.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HKLHMJLG_02851 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKLHMJLG_02852 2.5e-52 trxA O Belongs to the thioredoxin family
HKLHMJLG_02853 6.4e-303 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HKLHMJLG_02854 2.9e-179 etfA C Electron transfer flavoprotein
HKLHMJLG_02855 7.5e-138 etfB C Electron transfer flavoprotein
HKLHMJLG_02856 4.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HKLHMJLG_02857 9.2e-104 fadR K Transcriptional regulator
HKLHMJLG_02858 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKLHMJLG_02859 4.1e-124 ywbB S Protein of unknown function (DUF2711)
HKLHMJLG_02860 4.7e-67 yshE S membrane
HKLHMJLG_02861 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKLHMJLG_02862 0.0 polX L COG1796 DNA polymerase IV (family X)
HKLHMJLG_02863 1.1e-82 cvpA S membrane protein, required for colicin V production
HKLHMJLG_02864 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKLHMJLG_02865 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKLHMJLG_02866 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKLHMJLG_02867 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKLHMJLG_02868 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKLHMJLG_02869 2e-32 sspI S Belongs to the SspI family
HKLHMJLG_02870 5.8e-205 ysfB KT regulator
HKLHMJLG_02871 8.2e-260 glcD 1.1.3.15 C FAD binding domain
HKLHMJLG_02872 4.9e-254 glcF C Glycolate oxidase
HKLHMJLG_02873 0.0 cstA T Carbon starvation protein
HKLHMJLG_02874 1.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HKLHMJLG_02875 9.9e-144 araQ G transport system permease
HKLHMJLG_02876 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
HKLHMJLG_02877 1.5e-252 araN G carbohydrate transport
HKLHMJLG_02878 2.7e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HKLHMJLG_02879 7.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HKLHMJLG_02880 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HKLHMJLG_02881 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HKLHMJLG_02882 1.2e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HKLHMJLG_02883 1.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HKLHMJLG_02884 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
HKLHMJLG_02885 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HKLHMJLG_02886 2.6e-42 ysdA S Membrane
HKLHMJLG_02887 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKLHMJLG_02888 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HKLHMJLG_02889 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKLHMJLG_02890 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HKLHMJLG_02891 3.1e-40 lrgA S effector of murein hydrolase LrgA
HKLHMJLG_02892 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
HKLHMJLG_02893 0.0 lytS 2.7.13.3 T Histidine kinase
HKLHMJLG_02894 7.1e-152 ysaA S HAD-hyrolase-like
HKLHMJLG_02895 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKLHMJLG_02896 8e-154 ytxC S YtxC-like family
HKLHMJLG_02897 6.4e-109 ytxB S SNARE associated Golgi protein
HKLHMJLG_02898 4.3e-172 dnaI L Primosomal protein DnaI
HKLHMJLG_02899 9e-215 dnaB L Membrane attachment protein
HKLHMJLG_02900 4.7e-23 dnaB L Membrane attachment protein
HKLHMJLG_02901 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKLHMJLG_02902 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HKLHMJLG_02903 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKLHMJLG_02904 2e-67 ytcD K Transcriptional regulator
HKLHMJLG_02905 1.3e-205 ytbD EGP Major facilitator Superfamily
HKLHMJLG_02906 1.4e-158 ytbE S reductase
HKLHMJLG_02907 1.9e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKLHMJLG_02908 9.5e-107 ytaF P Probably functions as a manganese efflux pump
HKLHMJLG_02909 5.9e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKLHMJLG_02910 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKLHMJLG_02911 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HKLHMJLG_02912 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_02913 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HKLHMJLG_02914 3.1e-242 icd 1.1.1.42 C isocitrate
HKLHMJLG_02915 8.1e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HKLHMJLG_02916 7.8e-104 S aspartate phosphatase
HKLHMJLG_02917 1.4e-34
HKLHMJLG_02918 2.4e-66
HKLHMJLG_02920 8.5e-48 yjdF S Protein of unknown function (DUF2992)
HKLHMJLG_02921 1.1e-72 yeaL S membrane
HKLHMJLG_02922 3.6e-194 ytvI S sporulation integral membrane protein YtvI
HKLHMJLG_02923 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HKLHMJLG_02924 1.3e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HKLHMJLG_02925 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKLHMJLG_02926 1.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HKLHMJLG_02927 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKLHMJLG_02928 1.3e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
HKLHMJLG_02929 0.0 dnaE 2.7.7.7 L DNA polymerase
HKLHMJLG_02930 3.2e-56 ytrH S Sporulation protein YtrH
HKLHMJLG_02931 5.1e-87 ytrI
HKLHMJLG_02932 4.4e-23
HKLHMJLG_02933 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HKLHMJLG_02934 8.2e-48 ytpI S YtpI-like protein
HKLHMJLG_02935 7.5e-239 ytoI K transcriptional regulator containing CBS domains
HKLHMJLG_02936 2.5e-129 ytkL S Belongs to the UPF0173 family
HKLHMJLG_02937 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKLHMJLG_02939 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
HKLHMJLG_02940 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKLHMJLG_02941 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HKLHMJLG_02942 5.3e-40 L COG2963 Transposase and inactivated derivatives
HKLHMJLG_02943 1.2e-121 L Molecular Function DNA binding, Biological Process DNA recombination
HKLHMJLG_02944 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKLHMJLG_02945 1.4e-184 ytxK 2.1.1.72 L DNA methylase
HKLHMJLG_02946 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKLHMJLG_02947 1.6e-60 ytfJ S Sporulation protein YtfJ
HKLHMJLG_02948 1.4e-108 ytfI S Protein of unknown function (DUF2953)
HKLHMJLG_02949 4.5e-88 yteJ S RDD family
HKLHMJLG_02950 6.4e-182 sppA OU signal peptide peptidase SppA
HKLHMJLG_02951 3.3e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKLHMJLG_02952 0.0 ytcJ S amidohydrolase
HKLHMJLG_02953 3.5e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HKLHMJLG_02954 3.9e-31 sspB S spore protein
HKLHMJLG_02955 1.3e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKLHMJLG_02956 5.4e-209 iscS2 2.8.1.7 E Cysteine desulfurase
HKLHMJLG_02957 4e-240 braB E Component of the transport system for branched-chain amino acids
HKLHMJLG_02958 5.6e-263 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKLHMJLG_02959 8.6e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HKLHMJLG_02960 7.7e-109 yttP K Transcriptional regulator
HKLHMJLG_02961 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
HKLHMJLG_02962 1.7e-283 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HKLHMJLG_02963 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKLHMJLG_02964 6.5e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HKLHMJLG_02969 1.9e-32
HKLHMJLG_02970 1.3e-221 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HKLHMJLG_02971 7.3e-09
HKLHMJLG_02972 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
HKLHMJLG_02974 5.9e-140 E GDSL-like Lipase/Acylhydrolase family
HKLHMJLG_02975 1.1e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKLHMJLG_02976 7.5e-149 K Transcriptional regulator
HKLHMJLG_02977 5.2e-125 azlC E AzlC protein
HKLHMJLG_02978 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
HKLHMJLG_02979 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKLHMJLG_02980 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HKLHMJLG_02981 9.8e-120 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HKLHMJLG_02982 1.2e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HKLHMJLG_02983 6.6e-231 acuC BQ histone deacetylase
HKLHMJLG_02984 3.7e-120 motS N Flagellar motor protein
HKLHMJLG_02985 5.1e-145 motA N flagellar motor
HKLHMJLG_02986 2.9e-182 ccpA K catabolite control protein A
HKLHMJLG_02987 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HKLHMJLG_02988 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
HKLHMJLG_02989 1.7e-16 ytxH S COG4980 Gas vesicle protein
HKLHMJLG_02990 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKLHMJLG_02991 4.2e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HKLHMJLG_02992 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HKLHMJLG_02993 2e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKLHMJLG_02994 6.4e-148 ytpQ S Belongs to the UPF0354 family
HKLHMJLG_02995 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKLHMJLG_02996 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HKLHMJLG_02997 7.5e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HKLHMJLG_02998 1.7e-51 ytzB S small secreted protein
HKLHMJLG_02999 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HKLHMJLG_03000 2.1e-165 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HKLHMJLG_03001 1.4e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKLHMJLG_03002 3.5e-45 ytzH S YtzH-like protein
HKLHMJLG_03003 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
HKLHMJLG_03004 6.1e-179 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HKLHMJLG_03005 2.9e-168 ytlQ
HKLHMJLG_03006 1.5e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HKLHMJLG_03007 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKLHMJLG_03008 1.2e-271 pepV 3.5.1.18 E Dipeptidase
HKLHMJLG_03009 5.9e-228 pbuO S permease
HKLHMJLG_03010 4.9e-218 ythQ U Bacterial ABC transporter protein EcsB
HKLHMJLG_03011 4.9e-128 ythP V ABC transporter
HKLHMJLG_03012 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HKLHMJLG_03013 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKLHMJLG_03014 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKLHMJLG_03015 1.3e-235 ytfP S HI0933-like protein
HKLHMJLG_03016 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HKLHMJLG_03017 9e-26 yteV S Sporulation protein Cse60
HKLHMJLG_03018 2e-186 msmR K Transcriptional regulator
HKLHMJLG_03019 5.7e-244 msmE G Bacterial extracellular solute-binding protein
HKLHMJLG_03020 2.6e-166 amyD G Binding-protein-dependent transport system inner membrane component
HKLHMJLG_03021 1.4e-142 amyC P ABC transporter (permease)
HKLHMJLG_03022 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HKLHMJLG_03023 2.4e-86 M Acetyltransferase (GNAT) domain
HKLHMJLG_03024 5.6e-52 ytwF P Sulfurtransferase
HKLHMJLG_03025 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKLHMJLG_03026 1.2e-52 ytvB S Protein of unknown function (DUF4257)
HKLHMJLG_03027 6.9e-139 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HKLHMJLG_03028 7.3e-209 yttB EGP Major facilitator Superfamily
HKLHMJLG_03029 1.2e-129 ywaF S Integral membrane protein
HKLHMJLG_03030 0.0 bceB V ABC transporter (permease)
HKLHMJLG_03031 5.8e-135 bceA V ABC transporter, ATP-binding protein
HKLHMJLG_03032 8.4e-174 T PhoQ Sensor
HKLHMJLG_03033 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_03034 2.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HKLHMJLG_03035 1.3e-125 ytrE V ABC transporter, ATP-binding protein
HKLHMJLG_03036 7.9e-161
HKLHMJLG_03037 8.2e-174 P ABC-2 family transporter protein
HKLHMJLG_03038 1e-160 S ABC-2 family transporter protein
HKLHMJLG_03039 3.8e-162 ytrB P abc transporter atp-binding protein
HKLHMJLG_03040 1.5e-65 ytrA K GntR family transcriptional regulator
HKLHMJLG_03042 1.3e-39 ytzC S Protein of unknown function (DUF2524)
HKLHMJLG_03043 2.1e-190 yhcC S Fe-S oxidoreductase
HKLHMJLG_03044 8.7e-107 ytqB J Putative rRNA methylase
HKLHMJLG_03046 8.4e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HKLHMJLG_03047 6.6e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
HKLHMJLG_03048 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HKLHMJLG_03049 2.5e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HKLHMJLG_03050 0.0 asnB 6.3.5.4 E Asparagine synthase
HKLHMJLG_03051 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKLHMJLG_03052 3.7e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HKLHMJLG_03053 1.6e-38 ytmB S Protein of unknown function (DUF2584)
HKLHMJLG_03054 2.3e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HKLHMJLG_03055 3.3e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HKLHMJLG_03056 8.3e-145 ytlC P ABC transporter
HKLHMJLG_03057 5.8e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HKLHMJLG_03058 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HKLHMJLG_03059 1.7e-61 ytkC S Bacteriophage holin family
HKLHMJLG_03060 1.6e-76 dps P Belongs to the Dps family
HKLHMJLG_03062 1.4e-75 ytkA S YtkA-like
HKLHMJLG_03063 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKLHMJLG_03064 1.8e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HKLHMJLG_03065 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HKLHMJLG_03066 3e-40 rpmE2 J Ribosomal protein L31
HKLHMJLG_03067 2e-239 cydA 1.10.3.14 C oxidase, subunit
HKLHMJLG_03068 9.2e-184 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HKLHMJLG_03069 2.3e-24 S Domain of Unknown Function (DUF1540)
HKLHMJLG_03070 3.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HKLHMJLG_03071 1.9e-275 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HKLHMJLG_03072 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HKLHMJLG_03073 5.5e-155 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HKLHMJLG_03074 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HKLHMJLG_03075 1.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
HKLHMJLG_03076 2e-132 dksA T COG1734 DnaK suppressor protein
HKLHMJLG_03077 9e-78 tspO T membrane
HKLHMJLG_03086 7.8e-08
HKLHMJLG_03087 1.3e-09
HKLHMJLG_03094 1.6e-08
HKLHMJLG_03099 3.4e-39 S COG NOG14552 non supervised orthologous group
HKLHMJLG_03101 3.3e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
HKLHMJLG_03102 4.2e-177 yuaG 3.4.21.72 S protein conserved in bacteria
HKLHMJLG_03103 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HKLHMJLG_03104 7.4e-83 yuaE S DinB superfamily
HKLHMJLG_03105 1.2e-108 yuaD S MOSC domain
HKLHMJLG_03106 2.1e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
HKLHMJLG_03107 5.5e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HKLHMJLG_03108 2.7e-97 yuaC K Belongs to the GbsR family
HKLHMJLG_03109 2.1e-94 yuaB
HKLHMJLG_03110 5.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
HKLHMJLG_03111 2.5e-147 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKLHMJLG_03112 4.1e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HKLHMJLG_03113 1.3e-124 G Cupin
HKLHMJLG_03115 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKLHMJLG_03116 9e-196 yubA S transporter activity
HKLHMJLG_03117 2.7e-185 ygjR S Oxidoreductase
HKLHMJLG_03118 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HKLHMJLG_03119 3.7e-237 mcpA NT chemotaxis protein
HKLHMJLG_03120 1.6e-224 mcpA NT chemotaxis protein
HKLHMJLG_03121 1.5e-238 mcpA NT chemotaxis protein
HKLHMJLG_03122 2.6e-219 mcpA NT chemotaxis protein
HKLHMJLG_03123 2.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HKLHMJLG_03124 4.8e-41
HKLHMJLG_03125 1.3e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HKLHMJLG_03126 2.4e-77 yugU S Uncharacterised protein family UPF0047
HKLHMJLG_03127 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HKLHMJLG_03128 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HKLHMJLG_03129 8.3e-117 yugP S Zn-dependent protease
HKLHMJLG_03130 4.5e-18
HKLHMJLG_03131 1.1e-26 mstX S Membrane-integrating protein Mistic
HKLHMJLG_03132 1.8e-181 yugO P COG1226 Kef-type K transport systems
HKLHMJLG_03133 1.3e-72 yugN S YugN-like family
HKLHMJLG_03135 5.6e-258 pgi 5.3.1.9 G Belongs to the GPI family
HKLHMJLG_03136 1.8e-96 S NADPH-dependent FMN reductase
HKLHMJLG_03137 9.3e-118 ycaC Q Isochorismatase family
HKLHMJLG_03138 2.1e-229 yugK C Dehydrogenase
HKLHMJLG_03139 1.7e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HKLHMJLG_03140 1.8e-34 yuzA S Domain of unknown function (DUF378)
HKLHMJLG_03141 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HKLHMJLG_03142 2.7e-208 yugH 2.6.1.1 E Aminotransferase
HKLHMJLG_03143 2e-83 alaR K Transcriptional regulator
HKLHMJLG_03144 1.1e-155 yugF I Hydrolase
HKLHMJLG_03145 3.2e-40 yugE S Domain of unknown function (DUF1871)
HKLHMJLG_03146 8.1e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HKLHMJLG_03147 1.4e-229 T PhoQ Sensor
HKLHMJLG_03148 3.1e-68 kapB G Kinase associated protein B
HKLHMJLG_03149 1.7e-117 kapD L the KinA pathway to sporulation
HKLHMJLG_03150 1.5e-185 yuxJ EGP Major facilitator Superfamily
HKLHMJLG_03151 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HKLHMJLG_03152 2.2e-72 yuxK S protein conserved in bacteria
HKLHMJLG_03153 9.3e-74 yufK S Family of unknown function (DUF5366)
HKLHMJLG_03154 5.8e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKLHMJLG_03155 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
HKLHMJLG_03156 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HKLHMJLG_03157 4.3e-286 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HKLHMJLG_03158 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
HKLHMJLG_03159 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HKLHMJLG_03160 4.7e-13
HKLHMJLG_03161 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HKLHMJLG_03162 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKLHMJLG_03163 2e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKLHMJLG_03164 6.5e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKLHMJLG_03165 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKLHMJLG_03166 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKLHMJLG_03167 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HKLHMJLG_03168 3.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
HKLHMJLG_03169 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKLHMJLG_03170 0.0 comP 2.7.13.3 T Histidine kinase
HKLHMJLG_03172 1.5e-147 comQ H Polyprenyl synthetase
HKLHMJLG_03174 4.7e-52 yuzC
HKLHMJLG_03175 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HKLHMJLG_03176 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKLHMJLG_03177 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
HKLHMJLG_03178 7.2e-68 yueI S Protein of unknown function (DUF1694)
HKLHMJLG_03179 2.8e-38 yueH S YueH-like protein
HKLHMJLG_03180 6.4e-34 yueG S Spore germination protein gerPA/gerPF
HKLHMJLG_03181 1.9e-187 yueF S transporter activity
HKLHMJLG_03182 1.6e-22 S Protein of unknown function (DUF2642)
HKLHMJLG_03183 3.7e-96 yueE S phosphohydrolase
HKLHMJLG_03184 6.6e-128 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKLHMJLG_03185 3.8e-76 yueC S Family of unknown function (DUF5383)
HKLHMJLG_03186 0.0 esaA S type VII secretion protein EsaA
HKLHMJLG_03187 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HKLHMJLG_03188 1.5e-204 essB S WXG100 protein secretion system (Wss), protein YukC
HKLHMJLG_03189 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
HKLHMJLG_03190 2.8e-45 esxA S Belongs to the WXG100 family
HKLHMJLG_03191 3.2e-228 yukF QT Transcriptional regulator
HKLHMJLG_03192 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HKLHMJLG_03193 7.5e-134 yukJ S Uncharacterized conserved protein (DUF2278)
HKLHMJLG_03194 1.3e-34 mbtH S MbtH-like protein
HKLHMJLG_03195 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_03196 3.3e-172 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HKLHMJLG_03197 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HKLHMJLG_03198 2.1e-224 entC 5.4.4.2 HQ Isochorismate synthase
HKLHMJLG_03199 3.5e-135 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMJLG_03200 3.6e-165 besA S Putative esterase
HKLHMJLG_03201 4.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
HKLHMJLG_03202 1.1e-101 bioY S Biotin biosynthesis protein
HKLHMJLG_03203 4e-208 yuiF S antiporter
HKLHMJLG_03204 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HKLHMJLG_03205 3.5e-77 yuiD S protein conserved in bacteria
HKLHMJLG_03206 4.6e-117 yuiC S protein conserved in bacteria
HKLHMJLG_03207 3.8e-27 yuiB S Putative membrane protein
HKLHMJLG_03208 4.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
HKLHMJLG_03209 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
HKLHMJLG_03211 1.2e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKLHMJLG_03212 4.8e-29
HKLHMJLG_03213 3.1e-71 CP Membrane
HKLHMJLG_03214 1.6e-123 V ABC transporter
HKLHMJLG_03216 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
HKLHMJLG_03218 4.7e-45 rimJ 2.3.1.128 J Alanine acetyltransferase
HKLHMJLG_03219 4e-20 rimJ 2.3.1.128 J Alanine acetyltransferase
HKLHMJLG_03220 1.9e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMJLG_03221 1.1e-62 erpA S Belongs to the HesB IscA family
HKLHMJLG_03222 3.7e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKLHMJLG_03223 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKLHMJLG_03224 2.4e-39 yuzB S Belongs to the UPF0349 family
HKLHMJLG_03225 1.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
HKLHMJLG_03226 3.3e-55 yuzD S protein conserved in bacteria
HKLHMJLG_03227 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HKLHMJLG_03228 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HKLHMJLG_03229 1.2e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKLHMJLG_03230 4e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HKLHMJLG_03231 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
HKLHMJLG_03232 2.7e-196 yutH S Spore coat protein
HKLHMJLG_03233 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HKLHMJLG_03234 1.4e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKLHMJLG_03235 1.2e-73 yutE S Protein of unknown function DUF86
HKLHMJLG_03236 1.7e-47 yutD S protein conserved in bacteria
HKLHMJLG_03237 9.8e-166 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HKLHMJLG_03238 6.4e-195 lytH M Peptidase, M23
HKLHMJLG_03239 5.6e-130 yunB S Sporulation protein YunB (Spo_YunB)
HKLHMJLG_03240 3.4e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKLHMJLG_03241 1.8e-145 yunE S membrane transporter protein
HKLHMJLG_03242 1.5e-168 yunF S Protein of unknown function DUF72
HKLHMJLG_03243 1.5e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
HKLHMJLG_03244 6.5e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HKLHMJLG_03245 8e-304 pucR QT COG2508 Regulator of polyketide synthase expression
HKLHMJLG_03248 8.1e-133 S Aspartate phosphatase response regulator
HKLHMJLG_03249 6.8e-134 L Molecular Function DNA binding, Biological Process DNA recombination
HKLHMJLG_03250 1.1e-40 L transposase activity
HKLHMJLG_03251 3.7e-69
HKLHMJLG_03252 3.2e-212 blt EGP Major facilitator Superfamily
HKLHMJLG_03253 1.2e-233 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HKLHMJLG_03254 2.3e-237 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HKLHMJLG_03255 2e-168 bsn L Ribonuclease
HKLHMJLG_03256 1.3e-207 msmX P Belongs to the ABC transporter superfamily
HKLHMJLG_03257 3.1e-133 yurK K UTRA
HKLHMJLG_03258 1.4e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HKLHMJLG_03259 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
HKLHMJLG_03260 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
HKLHMJLG_03261 1.1e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HKLHMJLG_03262 7.9e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HKLHMJLG_03263 5.9e-166 K helix_turn_helix, mercury resistance
HKLHMJLG_03264 3e-14
HKLHMJLG_03265 2.6e-76
HKLHMJLG_03266 2.7e-22 S Sporulation delaying protein SdpA
HKLHMJLG_03268 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HKLHMJLG_03269 1e-204 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HKLHMJLG_03270 1.3e-125 Q ubiE/COQ5 methyltransferase family
HKLHMJLG_03271 2.3e-23 yncE S Protein of unknown function (DUF2691)
HKLHMJLG_03272 1.6e-38 yncE S Protein of unknown function (DUF2691)
HKLHMJLG_03273 6.6e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HKLHMJLG_03274 3e-270 sufB O FeS cluster assembly
HKLHMJLG_03275 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HKLHMJLG_03276 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKLHMJLG_03277 7e-245 sufD O assembly protein SufD
HKLHMJLG_03278 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HKLHMJLG_03279 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HKLHMJLG_03280 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
HKLHMJLG_03281 2.6e-94 metI P COG2011 ABC-type metal ion transport system, permease component
HKLHMJLG_03282 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKLHMJLG_03283 5e-57 yusD S SCP-2 sterol transfer family
HKLHMJLG_03284 1.6e-54 yusE CO Thioredoxin
HKLHMJLG_03285 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HKLHMJLG_03286 3.7e-40 yusG S Protein of unknown function (DUF2553)
HKLHMJLG_03287 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HKLHMJLG_03288 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HKLHMJLG_03289 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HKLHMJLG_03290 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HKLHMJLG_03291 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HKLHMJLG_03292 1.2e-166 fadM E Proline dehydrogenase
HKLHMJLG_03293 3.9e-43
HKLHMJLG_03294 1.1e-53 yusN M Coat F domain
HKLHMJLG_03295 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
HKLHMJLG_03296 8.1e-288 yusP P Major facilitator superfamily
HKLHMJLG_03297 1.2e-155 ywbI2 K Transcriptional regulator
HKLHMJLG_03298 7.2e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HKLHMJLG_03299 5.8e-186 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKLHMJLG_03300 3.3e-39 yusU S Protein of unknown function (DUF2573)
HKLHMJLG_03301 1.4e-150 yusV 3.6.3.34 HP ABC transporter
HKLHMJLG_03302 1.6e-44 S YusW-like protein
HKLHMJLG_03303 0.0 pepF2 E COG1164 Oligoendopeptidase F
HKLHMJLG_03304 4.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMJLG_03305 3.6e-79 dps P Belongs to the Dps family
HKLHMJLG_03306 1.1e-240 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKLHMJLG_03307 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_03308 2.3e-251 cssS 2.7.13.3 T PhoQ Sensor
HKLHMJLG_03309 3.4e-24
HKLHMJLG_03310 2.2e-157 yuxN K Transcriptional regulator
HKLHMJLG_03311 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKLHMJLG_03312 6.6e-24 S Protein of unknown function (DUF3970)
HKLHMJLG_03313 4.2e-259 gerAA EG Spore germination protein
HKLHMJLG_03314 5e-188 gerAB E Spore germination protein
HKLHMJLG_03315 7.3e-211 gerAC S Spore germination B3/ GerAC like, C-terminal
HKLHMJLG_03316 1.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKLHMJLG_03317 1e-193 vraS 2.7.13.3 T Histidine kinase
HKLHMJLG_03318 1.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HKLHMJLG_03319 6.2e-133 liaG S Putative adhesin
HKLHMJLG_03320 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HKLHMJLG_03321 3.3e-46 liaI S membrane
HKLHMJLG_03322 4.7e-230 yvqJ EGP Major facilitator Superfamily
HKLHMJLG_03323 1.1e-101 yvqK 2.5.1.17 S Adenosyltransferase
HKLHMJLG_03324 2.3e-226 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HKLHMJLG_03325 1.6e-180 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMJLG_03326 1.1e-167 yvrC P ABC transporter substrate-binding protein
HKLHMJLG_03327 1.2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMJLG_03328 2.9e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
HKLHMJLG_03329 0.0 T PhoQ Sensor
HKLHMJLG_03330 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_03331 1.1e-36
HKLHMJLG_03332 9.9e-103 yvrI K RNA polymerase
HKLHMJLG_03333 1.6e-15 S YvrJ protein family
HKLHMJLG_03334 5.4e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
HKLHMJLG_03335 4.9e-67 yvrL S Regulatory protein YrvL
HKLHMJLG_03336 4.8e-148 fhuC 3.6.3.34 HP ABC transporter
HKLHMJLG_03337 2e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMJLG_03338 5.6e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMJLG_03339 4e-178 fhuD P ABC transporter
HKLHMJLG_03340 1.3e-236 yvsH E Arginine ornithine antiporter
HKLHMJLG_03341 3.6e-14 S Small spore protein J (Spore_SspJ)
HKLHMJLG_03342 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HKLHMJLG_03343 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKLHMJLG_03344 3.1e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HKLHMJLG_03345 2.2e-140 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HKLHMJLG_03346 1e-98 modB P COG4149 ABC-type molybdate transport system, permease component
HKLHMJLG_03347 1.3e-114 yfiK K Regulator
HKLHMJLG_03348 4.9e-183 T Histidine kinase
HKLHMJLG_03349 2.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
HKLHMJLG_03350 1.6e-194 yfiM V ABC-2 type transporter
HKLHMJLG_03351 5e-199 yfiN V COG0842 ABC-type multidrug transport system, permease component
HKLHMJLG_03352 5e-156 yvgN S reductase
HKLHMJLG_03353 1.4e-86 yvgO
HKLHMJLG_03354 1.1e-40 L transposase activity
HKLHMJLG_03355 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
HKLHMJLG_03356 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HKLHMJLG_03357 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HKLHMJLG_03358 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HKLHMJLG_03359 0.0 helD 3.6.4.12 L DNA helicase
HKLHMJLG_03360 3.1e-99 yvgT S membrane
HKLHMJLG_03361 5.2e-142 S Metallo-peptidase family M12
HKLHMJLG_03362 2e-73 bdbC O Required for disulfide bond formation in some proteins
HKLHMJLG_03363 1.2e-102 bdbD O Thioredoxin
HKLHMJLG_03364 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HKLHMJLG_03365 0.0 copA 3.6.3.54 P P-type ATPase
HKLHMJLG_03366 2.6e-29 copZ P Heavy-metal-associated domain
HKLHMJLG_03367 3.7e-48 csoR S transcriptional
HKLHMJLG_03368 2.6e-194 yvaA 1.1.1.371 S Oxidoreductase
HKLHMJLG_03369 2.7e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKLHMJLG_03370 3.1e-161 K Helix-turn-helix XRE-family like proteins
HKLHMJLG_03371 6.1e-219 ynfM EGP Major Facilitator Superfamily
HKLHMJLG_03372 4.8e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
HKLHMJLG_03373 4e-147 S Amidohydrolase
HKLHMJLG_03374 3.4e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKLHMJLG_03375 1.1e-46 ytnI O COG0695 Glutaredoxin and related proteins
HKLHMJLG_03376 2.9e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKLHMJLG_03377 8e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKLHMJLG_03378 2.9e-120 tcyM U Binding-protein-dependent transport system inner membrane component
HKLHMJLG_03379 2e-121 tcyL P Binding-protein-dependent transport system inner membrane component
HKLHMJLG_03380 6.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
HKLHMJLG_03381 8.4e-132 ytmJ ET Bacterial periplasmic substrate-binding proteins
HKLHMJLG_03382 1.7e-101 ytmI K Acetyltransferase (GNAT) domain
HKLHMJLG_03383 4.8e-165 ytlI K LysR substrate binding domain
HKLHMJLG_03384 1.1e-40 L transposase activity
HKLHMJLG_03385 6.8e-134 L Molecular Function DNA binding, Biological Process DNA recombination
HKLHMJLG_03386 6.9e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMJLG_03388 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HKLHMJLG_03389 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKLHMJLG_03390 7.4e-143 est 3.1.1.1 S Carboxylesterase
HKLHMJLG_03391 4.8e-24 secG U Preprotein translocase subunit SecG
HKLHMJLG_03392 6e-35 yvzC K Transcriptional
HKLHMJLG_03393 8.7e-69 K transcriptional
HKLHMJLG_03394 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
HKLHMJLG_03395 8.8e-53 yodB K transcriptional
HKLHMJLG_03396 1.3e-257 T His Kinase A (phosphoacceptor) domain
HKLHMJLG_03397 1.3e-122 K Transcriptional regulatory protein, C terminal
HKLHMJLG_03398 8.8e-139 mutG S ABC-2 family transporter protein
HKLHMJLG_03399 1.7e-123 spaE S ABC-2 family transporter protein
HKLHMJLG_03400 1.2e-126 mutF V ABC transporter, ATP-binding protein
HKLHMJLG_03401 1.8e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKLHMJLG_03402 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKLHMJLG_03403 7.8e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKLHMJLG_03404 1.1e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HKLHMJLG_03405 4.3e-76 yvbF K Belongs to the GbsR family
HKLHMJLG_03406 7.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKLHMJLG_03407 2.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKLHMJLG_03408 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKLHMJLG_03409 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HKLHMJLG_03410 1.9e-98 yvbF K Belongs to the GbsR family
HKLHMJLG_03411 5.2e-105 yvbG U UPF0056 membrane protein
HKLHMJLG_03412 1.6e-118 exoY M Membrane
HKLHMJLG_03413 0.0 tcaA S response to antibiotic
HKLHMJLG_03414 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
HKLHMJLG_03415 1.2e-211 EGP Major facilitator Superfamily
HKLHMJLG_03416 3.8e-181
HKLHMJLG_03417 1.8e-124 S GlcNAc-PI de-N-acetylase
HKLHMJLG_03418 2.5e-143 C WbqC-like protein family
HKLHMJLG_03419 2.6e-150 M Protein involved in cellulose biosynthesis
HKLHMJLG_03420 1.6e-235 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HKLHMJLG_03421 1.6e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
HKLHMJLG_03422 1.1e-217 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HKLHMJLG_03423 2.3e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKLHMJLG_03424 5.6e-239 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HKLHMJLG_03425 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKLHMJLG_03426 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HKLHMJLG_03427 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKLHMJLG_03428 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HKLHMJLG_03429 3.1e-184 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKLHMJLG_03430 1.5e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HKLHMJLG_03432 7.4e-253 araE EGP Major facilitator Superfamily
HKLHMJLG_03433 6.5e-204 araR K transcriptional
HKLHMJLG_03434 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKLHMJLG_03436 1.4e-156 yvbU K Transcriptional regulator
HKLHMJLG_03437 1.6e-158 yvbV EG EamA-like transporter family
HKLHMJLG_03438 8.5e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HKLHMJLG_03439 3.4e-260
HKLHMJLG_03440 1.4e-181 purR7 5.1.1.1 K Transcriptional regulator
HKLHMJLG_03441 2.6e-115 yyaS S Membrane
HKLHMJLG_03442 8.8e-167 3.1.3.104 S hydrolases of the HAD superfamily
HKLHMJLG_03443 7.7e-152 ybbH_1 K RpiR family transcriptional regulator
HKLHMJLG_03444 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
HKLHMJLG_03445 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
HKLHMJLG_03446 6.7e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HKLHMJLG_03447 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HKLHMJLG_03448 3.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HKLHMJLG_03449 2.8e-224 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKLHMJLG_03450 7.8e-121 yvfI K COG2186 Transcriptional regulators
HKLHMJLG_03451 3.8e-304 yvfH C L-lactate permease
HKLHMJLG_03452 7.7e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HKLHMJLG_03453 2.7e-32 yvfG S YvfG protein
HKLHMJLG_03454 1.5e-188 yvfF GM Exopolysaccharide biosynthesis protein
HKLHMJLG_03455 1.6e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HKLHMJLG_03456 1.2e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HKLHMJLG_03457 3.4e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HKLHMJLG_03458 1.8e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKLHMJLG_03459 5.2e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HKLHMJLG_03460 4.1e-203 epsI GM pyruvyl transferase
HKLHMJLG_03461 8.9e-195 epsH GT2 S Glycosyltransferase like family 2
HKLHMJLG_03462 1e-204 epsG S EpsG family
HKLHMJLG_03463 1.9e-214 epsF GT4 M Glycosyl transferases group 1
HKLHMJLG_03464 1.2e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKLHMJLG_03465 8.2e-218 epsD GT4 M Glycosyl transferase 4-like
HKLHMJLG_03466 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HKLHMJLG_03467 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HKLHMJLG_03468 1.1e-119 ywqC M biosynthesis protein
HKLHMJLG_03469 1.9e-77 slr K transcriptional
HKLHMJLG_03470 2.9e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HKLHMJLG_03472 6.8e-98 ywjB H RibD C-terminal domain
HKLHMJLG_03473 1.3e-111 yyaS S Membrane
HKLHMJLG_03474 6.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKLHMJLG_03475 1.6e-93 padC Q Phenolic acid decarboxylase
HKLHMJLG_03476 9.1e-17 S Protein of unknown function (DUF1433)
HKLHMJLG_03477 1.2e-39 S Protein of unknown function (DUF1433)
HKLHMJLG_03478 1.8e-16 S Protein of unknown function (DUF1433)
HKLHMJLG_03479 1.4e-270 I Pfam Lipase (class 3)
HKLHMJLG_03480 1.8e-34
HKLHMJLG_03482 6.7e-297 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
HKLHMJLG_03483 1.4e-218 rafB P LacY proton/sugar symporter
HKLHMJLG_03484 1.1e-183 scrR K transcriptional
HKLHMJLG_03485 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKLHMJLG_03486 2e-163 yraN K Transcriptional regulator
HKLHMJLG_03487 4.9e-215 yraM S PrpF protein
HKLHMJLG_03488 3.1e-251 EGP Sugar (and other) transporter
HKLHMJLG_03489 7.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HKLHMJLG_03490 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HKLHMJLG_03491 9.5e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HKLHMJLG_03492 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HKLHMJLG_03493 7.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHMJLG_03494 1.6e-79 M Ribonuclease
HKLHMJLG_03495 1.7e-27 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HKLHMJLG_03496 4.4e-21
HKLHMJLG_03497 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HKLHMJLG_03498 4.7e-36 crh G Phosphocarrier protein Chr
HKLHMJLG_03499 3.1e-170 whiA K May be required for sporulation
HKLHMJLG_03500 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HKLHMJLG_03501 1.1e-166 rapZ S Displays ATPase and GTPase activities
HKLHMJLG_03502 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HKLHMJLG_03503 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKLHMJLG_03504 4e-121 usp CBM50 M protein conserved in bacteria
HKLHMJLG_03505 1.2e-274 S COG0457 FOG TPR repeat
HKLHMJLG_03506 1.2e-191 sasA T Histidine kinase
HKLHMJLG_03507 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_03508 0.0 msbA2 3.6.3.44 V ABC transporter
HKLHMJLG_03509 4e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HKLHMJLG_03510 2.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKLHMJLG_03511 3.4e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKLHMJLG_03512 1.5e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKLHMJLG_03513 5.1e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HKLHMJLG_03514 3.8e-235 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKLHMJLG_03515 1.3e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKLHMJLG_03516 1.1e-206 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKLHMJLG_03517 1.8e-138 yvpB NU protein conserved in bacteria
HKLHMJLG_03518 5.4e-84 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HKLHMJLG_03519 5.3e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HKLHMJLG_03520 6.2e-151 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKLHMJLG_03521 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKLHMJLG_03522 5e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKLHMJLG_03523 1.2e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKLHMJLG_03524 1.1e-133 yvoA K transcriptional
HKLHMJLG_03525 1.2e-105 yxaF K Transcriptional regulator
HKLHMJLG_03526 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HKLHMJLG_03527 3.9e-41 yvlD S Membrane
HKLHMJLG_03528 9.6e-26 pspB KT PspC domain
HKLHMJLG_03529 3.2e-166 yvlB S Putative adhesin
HKLHMJLG_03530 1e-48 yvlA
HKLHMJLG_03531 3e-38 yvkN
HKLHMJLG_03532 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKLHMJLG_03533 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKLHMJLG_03534 7.6e-33 csbA S protein conserved in bacteria
HKLHMJLG_03535 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HKLHMJLG_03536 1e-108 yvkB K Transcriptional regulator
HKLHMJLG_03537 1.1e-226 yvkA EGP Major facilitator Superfamily
HKLHMJLG_03538 4.3e-176 S Psort location CytoplasmicMembrane, score
HKLHMJLG_03539 1.4e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKLHMJLG_03540 1.5e-55 swrA S Swarming motility protein
HKLHMJLG_03541 1.2e-255 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HKLHMJLG_03542 2.4e-227 ywoF P Right handed beta helix region
HKLHMJLG_03543 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HKLHMJLG_03544 1e-122 ftsE D cell division ATP-binding protein FtsE
HKLHMJLG_03545 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
HKLHMJLG_03546 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HKLHMJLG_03547 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKLHMJLG_03548 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKLHMJLG_03549 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKLHMJLG_03550 6.8e-68
HKLHMJLG_03551 2.6e-10 fliT S bacterial-type flagellum organization
HKLHMJLG_03552 3e-66 fliS N flagellar protein FliS
HKLHMJLG_03553 9.6e-262 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HKLHMJLG_03554 3.9e-116 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HKLHMJLG_03555 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HKLHMJLG_03556 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HKLHMJLG_03557 1.5e-79 yviE
HKLHMJLG_03558 6.1e-163 flgL N Belongs to the bacterial flagellin family
HKLHMJLG_03559 1.1e-273 flgK N flagellar hook-associated protein
HKLHMJLG_03560 2.6e-80 flgN NOU FlgN protein
HKLHMJLG_03561 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
HKLHMJLG_03562 1.4e-74 yvyF S flagellar protein
HKLHMJLG_03563 1.6e-77 comFC S Phosphoribosyl transferase domain
HKLHMJLG_03564 1.5e-43 comFB S Late competence development protein ComFB
HKLHMJLG_03565 1.5e-261 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HKLHMJLG_03566 1.4e-158 degV S protein conserved in bacteria
HKLHMJLG_03567 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKLHMJLG_03568 3.8e-152 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HKLHMJLG_03569 2.1e-07 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HKLHMJLG_03570 2.2e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HKLHMJLG_03571 8.6e-173 yvhJ K Transcriptional regulator
HKLHMJLG_03572 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HKLHMJLG_03573 8e-240 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HKLHMJLG_03574 6.8e-144 tuaG GT2 M Glycosyltransferase like family 2
HKLHMJLG_03575 3.5e-115 tuaF M protein involved in exopolysaccharide biosynthesis
HKLHMJLG_03576 3.6e-255 tuaE M Teichuronic acid biosynthesis protein
HKLHMJLG_03577 2.5e-250 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKLHMJLG_03578 1.1e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HKLHMJLG_03579 1.5e-256 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKLHMJLG_03580 2.4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HKLHMJLG_03581 9.1e-209 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKLHMJLG_03582 1.3e-306 lytB 3.5.1.28 D Stage II sporulation protein
HKLHMJLG_03583 5.9e-30
HKLHMJLG_03584 1.7e-136 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HKLHMJLG_03585 2.7e-184 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKLHMJLG_03586 3.7e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKLHMJLG_03587 1.3e-181 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKLHMJLG_03588 7.5e-136 tagG GM Transport permease protein
HKLHMJLG_03589 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKLHMJLG_03590 1e-258 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HKLHMJLG_03591 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HKLHMJLG_03592 3.4e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKLHMJLG_03593 2e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKLHMJLG_03594 5.3e-244 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKLHMJLG_03595 1.8e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HKLHMJLG_03596 3.5e-266 gerBA EG Spore germination protein
HKLHMJLG_03597 8.3e-199 gerBB E Spore germination protein
HKLHMJLG_03598 1.4e-214 gerAC S Spore germination protein
HKLHMJLG_03599 2.8e-268 GT2,GT4 J Glycosyl transferase family 2
HKLHMJLG_03600 4.9e-249 ywtG EGP Major facilitator Superfamily
HKLHMJLG_03601 1.9e-178 ywtF K Transcriptional regulator
HKLHMJLG_03602 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HKLHMJLG_03603 4.1e-37 yttA 2.7.13.3 S Pfam Transposase IS66
HKLHMJLG_03604 2e-241 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HKLHMJLG_03605 1.3e-20 ywtC
HKLHMJLG_03606 2.6e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HKLHMJLG_03607 2.3e-70 pgsC S biosynthesis protein
HKLHMJLG_03608 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HKLHMJLG_03609 1.3e-183 gerKA EG Spore germination protein
HKLHMJLG_03610 1.1e-190 gerKB E Spore germination protein
HKLHMJLG_03611 2e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
HKLHMJLG_03612 1.2e-177 rbsR K transcriptional
HKLHMJLG_03613 1.5e-158 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKLHMJLG_03614 9.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKLHMJLG_03615 3.4e-280 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HKLHMJLG_03616 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HKLHMJLG_03617 3.3e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HKLHMJLG_03618 1.5e-89 batE T Sh3 type 3 domain protein
HKLHMJLG_03619 9e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HKLHMJLG_03620 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HKLHMJLG_03621 1.2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HKLHMJLG_03622 9e-167 alsR K LysR substrate binding domain
HKLHMJLG_03624 4.7e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKLHMJLG_03625 4.4e-126 ywrJ
HKLHMJLG_03626 9.2e-132 cotB
HKLHMJLG_03627 4.5e-213 cotH M Spore Coat
HKLHMJLG_03628 2e-09
HKLHMJLG_03629 5.6e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HKLHMJLG_03630 1.5e-302 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HKLHMJLG_03631 1.1e-83 ywrC K Transcriptional regulator
HKLHMJLG_03632 1.3e-102 ywrB P Chromate transporter
HKLHMJLG_03633 4.4e-89 ywrA P COG2059 Chromate transport protein ChrA
HKLHMJLG_03634 1.1e-53 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HKLHMJLG_03635 5.2e-92
HKLHMJLG_03636 4.3e-66 S SMI1 / KNR4 family (SUKH-1)
HKLHMJLG_03637 1.1e-103 S Domain of unknown function (DUF1851)
HKLHMJLG_03638 7.3e-79 S LXG domain of WXG superfamily
HKLHMJLG_03639 5.2e-99 L Integrase core domain
HKLHMJLG_03640 1.2e-91
HKLHMJLG_03641 5.9e-260 ywqJ S Pre-toxin TG
HKLHMJLG_03642 9.5e-37 ywqI S Family of unknown function (DUF5344)
HKLHMJLG_03643 1.3e-27 S Domain of unknown function (DUF5082)
HKLHMJLG_03645 6e-151 ywqG S Domain of unknown function (DUF1963)
HKLHMJLG_03646 9.5e-250 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKLHMJLG_03647 3.5e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HKLHMJLG_03648 4.3e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HKLHMJLG_03649 5.2e-112 ywqC M biosynthesis protein
HKLHMJLG_03650 1.3e-14
HKLHMJLG_03651 1.2e-307 ywqB S SWIM zinc finger
HKLHMJLG_03652 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HKLHMJLG_03653 2.5e-158 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HKLHMJLG_03654 7.5e-138 glcR K DeoR C terminal sensor domain
HKLHMJLG_03655 7.5e-58 ssbB L Single-stranded DNA-binding protein
HKLHMJLG_03656 4e-62 ywpG
HKLHMJLG_03657 3.9e-69 ywpF S YwpF-like protein
HKLHMJLG_03658 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKLHMJLG_03659 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKLHMJLG_03660 1.1e-200 S aspartate phosphatase
HKLHMJLG_03661 6.1e-146 flhP N flagellar basal body
HKLHMJLG_03662 4.1e-123 flhO N flagellar basal body
HKLHMJLG_03663 2.7e-180 mbl D Rod shape-determining protein
HKLHMJLG_03664 1.8e-44 spoIIID K Stage III sporulation protein D
HKLHMJLG_03665 8.5e-72 ywoH K transcriptional
HKLHMJLG_03666 3.8e-213 ywoG EGP Major facilitator Superfamily
HKLHMJLG_03667 4.5e-277 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HKLHMJLG_03668 4e-243 ywoD EGP Major facilitator superfamily
HKLHMJLG_03669 5.7e-103 phzA Q Isochorismatase family
HKLHMJLG_03670 2.1e-227 amt P Ammonium transporter
HKLHMJLG_03671 2e-58 nrgB K Belongs to the P(II) protein family
HKLHMJLG_03672 4.9e-210 ftsW D Belongs to the SEDS family
HKLHMJLG_03673 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HKLHMJLG_03674 5.1e-72 ywnJ S VanZ like family
HKLHMJLG_03675 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HKLHMJLG_03676 5.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HKLHMJLG_03677 1.2e-10 ywnC S Family of unknown function (DUF5362)
HKLHMJLG_03678 4.2e-69 ywnF S Family of unknown function (DUF5392)
HKLHMJLG_03679 4.5e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKLHMJLG_03680 2.2e-53 ywnC S Family of unknown function (DUF5362)
HKLHMJLG_03681 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HKLHMJLG_03682 1.4e-66 ywnA K Transcriptional regulator
HKLHMJLG_03683 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HKLHMJLG_03684 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HKLHMJLG_03685 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HKLHMJLG_03686 7.4e-10 csbD K CsbD-like
HKLHMJLG_03687 2.1e-82 ywmF S Peptidase M50
HKLHMJLG_03688 2.8e-93 S response regulator aspartate phosphatase
HKLHMJLG_03689 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HKLHMJLG_03690 1.3e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HKLHMJLG_03692 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HKLHMJLG_03693 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HKLHMJLG_03694 1.9e-189 spoIID D Stage II sporulation protein D
HKLHMJLG_03695 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKLHMJLG_03696 3.3e-135 ywmB S TATA-box binding
HKLHMJLG_03697 1.3e-32 ywzB S membrane
HKLHMJLG_03698 1.2e-90 ywmA
HKLHMJLG_03699 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HKLHMJLG_03700 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKLHMJLG_03701 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKLHMJLG_03702 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKLHMJLG_03703 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKLHMJLG_03704 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKLHMJLG_03705 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKLHMJLG_03706 9.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
HKLHMJLG_03707 2.1e-61 atpI S ATP synthase
HKLHMJLG_03708 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKLHMJLG_03709 3e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKLHMJLG_03710 2.2e-96 ywlG S Belongs to the UPF0340 family
HKLHMJLG_03711 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HKLHMJLG_03712 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKLHMJLG_03713 1.7e-83 mntP P Probably functions as a manganese efflux pump
HKLHMJLG_03714 3.3e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKLHMJLG_03715 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HKLHMJLG_03716 8.1e-120 spoIIR S stage II sporulation protein R
HKLHMJLG_03717 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
HKLHMJLG_03719 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKLHMJLG_03720 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKLHMJLG_03721 5.8e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKLHMJLG_03722 4.4e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HKLHMJLG_03723 3.7e-155 ywkB S Membrane transport protein
HKLHMJLG_03724 0.0 sfcA 1.1.1.38 C malic enzyme
HKLHMJLG_03725 1.7e-102 tdk 2.7.1.21 F thymidine kinase
HKLHMJLG_03726 1.1e-32 rpmE J Binds the 23S rRNA
HKLHMJLG_03727 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKLHMJLG_03728 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HKLHMJLG_03729 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKLHMJLG_03730 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKLHMJLG_03731 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HKLHMJLG_03732 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
HKLHMJLG_03733 6.4e-93 ywjG S Domain of unknown function (DUF2529)
HKLHMJLG_03734 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKLHMJLG_03735 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKLHMJLG_03736 0.0 fadF C COG0247 Fe-S oxidoreductase
HKLHMJLG_03737 5.4e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HKLHMJLG_03738 4.7e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HKLHMJLG_03739 7.1e-43 ywjC
HKLHMJLG_03740 0.0 ywjA V ABC transporter
HKLHMJLG_03741 1e-63 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKLHMJLG_03742 4.6e-194 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKLHMJLG_03743 1.2e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKLHMJLG_03744 4.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
HKLHMJLG_03745 1.6e-97 narJ 1.7.5.1 C nitrate reductase
HKLHMJLG_03746 5.9e-293 narH 1.7.5.1 C Nitrate reductase, beta
HKLHMJLG_03747 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKLHMJLG_03748 4.5e-85 arfM T cyclic nucleotide binding
HKLHMJLG_03749 1.3e-139 ywiC S YwiC-like protein
HKLHMJLG_03750 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HKLHMJLG_03751 5.8e-214 narK P COG2223 Nitrate nitrite transporter
HKLHMJLG_03752 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HKLHMJLG_03753 1.2e-73 ywiB S protein conserved in bacteria
HKLHMJLG_03755 1.9e-229 ywhL CO amine dehydrogenase activity
HKLHMJLG_03756 2.9e-222 ywhK CO amine dehydrogenase activity
HKLHMJLG_03757 3.3e-81 S aspartate phosphatase
HKLHMJLG_03759 2.6e-29 ydcG K sequence-specific DNA binding
HKLHMJLG_03760 5e-33
HKLHMJLG_03761 2e-28 S Domain of unknown function (DUF4177)
HKLHMJLG_03763 1.1e-76 CP Membrane
HKLHMJLG_03766 3.5e-168 speB 3.5.3.11 E Belongs to the arginase family
HKLHMJLG_03767 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HKLHMJLG_03768 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKLHMJLG_03769 6.5e-83
HKLHMJLG_03770 3.1e-95 ywhD S YwhD family
HKLHMJLG_03771 1.2e-117 ywhC S Peptidase family M50
HKLHMJLG_03772 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HKLHMJLG_03773 3.6e-70 ywhA K Transcriptional regulator
HKLHMJLG_03774 1.3e-246 yhdG_1 E C-terminus of AA_permease
HKLHMJLG_03775 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
HKLHMJLG_03776 7.9e-257 ywfO S COG1078 HD superfamily phosphohydrolases
HKLHMJLG_03777 6.9e-36 ywzC S Belongs to the UPF0741 family
HKLHMJLG_03778 3e-110 rsfA_1
HKLHMJLG_03779 4.8e-51 padR K PadR family transcriptional regulator
HKLHMJLG_03780 8.1e-94 S membrane
HKLHMJLG_03781 1.6e-166 V ABC transporter, ATP-binding protein
HKLHMJLG_03782 3.5e-169 yhcI S ABC transporter (permease)
HKLHMJLG_03785 3.8e-184
HKLHMJLG_03787 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HKLHMJLG_03788 1.9e-161 cysL K Transcriptional regulator
HKLHMJLG_03789 3.3e-159 MA20_14895 S Conserved hypothetical protein 698
HKLHMJLG_03790 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HKLHMJLG_03791 1.1e-146 ywfI C May function as heme-dependent peroxidase
HKLHMJLG_03792 1.4e-139 IQ Enoyl-(Acyl carrier protein) reductase
HKLHMJLG_03793 3.5e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HKLHMJLG_03794 4.7e-208 bacE EGP Major facilitator Superfamily
HKLHMJLG_03795 2e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HKLHMJLG_03796 4.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKLHMJLG_03797 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HKLHMJLG_03798 1.5e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HKLHMJLG_03799 2.9e-224 ywfA EGP Major facilitator Superfamily
HKLHMJLG_03800 4.8e-208 tcaB EGP Major facilitator Superfamily
HKLHMJLG_03801 7.5e-261 lysP E amino acid
HKLHMJLG_03802 0.0 rocB E arginine degradation protein
HKLHMJLG_03803 2.5e-294 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HKLHMJLG_03804 2.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKLHMJLG_03805 2.2e-160 T PhoQ Sensor
HKLHMJLG_03806 3.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_03807 3.2e-65
HKLHMJLG_03808 1.4e-119 S ABC-2 family transporter protein
HKLHMJLG_03809 6.7e-173 bcrA5 V ABC transporter, ATP-binding protein
HKLHMJLG_03810 3.5e-87 spsL 5.1.3.13 M Spore Coat
HKLHMJLG_03811 3.4e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKLHMJLG_03812 2.7e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKLHMJLG_03813 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKLHMJLG_03814 6.8e-184 spsG M Spore Coat
HKLHMJLG_03815 1.4e-133 spsF M Spore Coat
HKLHMJLG_03816 2.9e-215 spsE 2.5.1.56 M acid synthase
HKLHMJLG_03817 5.9e-160 spsD 2.3.1.210 K Spore Coat
HKLHMJLG_03818 1.5e-222 spsC E Belongs to the DegT DnrJ EryC1 family
HKLHMJLG_03819 1.8e-275 spsB M Capsule polysaccharide biosynthesis protein
HKLHMJLG_03820 2.6e-143 spsA M Spore Coat
HKLHMJLG_03821 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HKLHMJLG_03822 4.2e-46 ywdK S small membrane protein
HKLHMJLG_03823 2e-231 ywdJ F Xanthine uracil
HKLHMJLG_03824 7.3e-41 ywdI S Family of unknown function (DUF5327)
HKLHMJLG_03825 1.9e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKLHMJLG_03826 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
HKLHMJLG_03828 2.6e-88 ywdD
HKLHMJLG_03829 1.4e-56 pex K Transcriptional regulator PadR-like family
HKLHMJLG_03830 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKLHMJLG_03831 9.7e-20 ywdA
HKLHMJLG_03832 3e-289 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
HKLHMJLG_03833 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKLHMJLG_03834 2e-07 sacT K transcriptional antiterminator
HKLHMJLG_03835 8.3e-151 sacT K transcriptional antiterminator
HKLHMJLG_03837 0.0 vpr O Belongs to the peptidase S8 family
HKLHMJLG_03838 2.1e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKLHMJLG_03839 1.4e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HKLHMJLG_03840 2.8e-208 rodA D Belongs to the SEDS family
HKLHMJLG_03841 8.2e-80 ysnE K acetyltransferase
HKLHMJLG_03842 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
HKLHMJLG_03843 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HKLHMJLG_03844 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HKLHMJLG_03845 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKLHMJLG_03846 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HKLHMJLG_03847 8.4e-27 ywzA S membrane
HKLHMJLG_03848 2.5e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HKLHMJLG_03849 5.7e-230 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKLHMJLG_03850 9.3e-63 gtcA S GtrA-like protein
HKLHMJLG_03851 1.6e-111 ywcC K Bacterial regulatory proteins, tetR family
HKLHMJLG_03853 1.9e-129 H Methionine biosynthesis protein MetW
HKLHMJLG_03854 3.5e-131 S Streptomycin biosynthesis protein StrF
HKLHMJLG_03855 5.5e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HKLHMJLG_03856 2.4e-242 ywbN P Dyp-type peroxidase family protein
HKLHMJLG_03857 1.9e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKLHMJLG_03858 4.3e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKLHMJLG_03859 8.2e-152 ywbI K Transcriptional regulator
HKLHMJLG_03860 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HKLHMJLG_03861 1.5e-110 ywbG M effector of murein hydrolase
HKLHMJLG_03862 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HKLHMJLG_03863 2.2e-142 mta K transcriptional
HKLHMJLG_03864 3.9e-170 yjfC O Predicted Zn-dependent protease (DUF2268)
HKLHMJLG_03865 5.5e-225 ywbD 2.1.1.191 J Methyltransferase
HKLHMJLG_03866 2.9e-66 ywbC 4.4.1.5 E glyoxalase
HKLHMJLG_03867 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMJLG_03868 1.1e-266 epr 3.4.21.62 O Belongs to the peptidase S8 family
HKLHMJLG_03869 1.1e-163 gspA M General stress
HKLHMJLG_03870 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
HKLHMJLG_03871 1.7e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HKLHMJLG_03872 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
HKLHMJLG_03873 6e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_03874 3.7e-229 dltB M membrane protein involved in D-alanine export
HKLHMJLG_03875 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMJLG_03876 1.2e-192 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKLHMJLG_03877 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HKLHMJLG_03878 7.8e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HKLHMJLG_03879 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKLHMJLG_03880 2.2e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMJLG_03881 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HKLHMJLG_03882 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HKLHMJLG_03883 2.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HKLHMJLG_03884 1.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMJLG_03885 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMJLG_03886 4e-167 cbrA3 P Periplasmic binding protein
HKLHMJLG_03887 2.2e-57 arsR K transcriptional
HKLHMJLG_03888 2.9e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKLHMJLG_03889 2e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKLHMJLG_03890 5.9e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKLHMJLG_03891 6.4e-230 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMJLG_03892 2.5e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLHMJLG_03893 5.6e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HKLHMJLG_03894 1.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKLHMJLG_03895 3.8e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HKLHMJLG_03896 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HKLHMJLG_03897 7.2e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HKLHMJLG_03898 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HKLHMJLG_03899 1.2e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKLHMJLG_03900 8.2e-294 cydD V ATP-binding protein
HKLHMJLG_03901 0.0 cydD V ATP-binding
HKLHMJLG_03902 4.2e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HKLHMJLG_03903 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
HKLHMJLG_03904 1.5e-215 cimH C COG3493 Na citrate symporter
HKLHMJLG_03905 7.1e-158 yxkH G Polysaccharide deacetylase
HKLHMJLG_03906 3.5e-205 msmK P Belongs to the ABC transporter superfamily
HKLHMJLG_03907 2.1e-168 lrp QT PucR C-terminal helix-turn-helix domain
HKLHMJLG_03908 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKLHMJLG_03909 3.8e-87 yxkC S Domain of unknown function (DUF4352)
HKLHMJLG_03910 1.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKLHMJLG_03911 8e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HKLHMJLG_03914 1.8e-86 yxjI S LURP-one-related
HKLHMJLG_03915 1.1e-217 yxjG 2.1.1.14 E Methionine synthase
HKLHMJLG_03916 4.8e-157 rlmA 2.1.1.187 Q Methyltransferase domain
HKLHMJLG_03917 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKLHMJLG_03918 2.7e-75 T Domain of unknown function (DUF4163)
HKLHMJLG_03919 1.4e-50 yxiS
HKLHMJLG_03920 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HKLHMJLG_03921 1.8e-221 citH C Citrate transporter
HKLHMJLG_03922 2.5e-143 exoK GH16 M licheninase activity
HKLHMJLG_03923 5.3e-150 licT K transcriptional antiterminator
HKLHMJLG_03924 9.3e-223 yxiO S COG2270 Permeases of the major facilitator superfamily
HKLHMJLG_03925 9.9e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HKLHMJLG_03928 1.6e-61 S SMI1-KNR4 cell-wall
HKLHMJLG_03929 6.1e-82 yxiI S Protein of unknown function (DUF2716)
HKLHMJLG_03931 1.7e-20
HKLHMJLG_03932 1.2e-13 S YxiJ-like protein
HKLHMJLG_03933 1.4e-105
HKLHMJLG_03934 1.9e-72
HKLHMJLG_03935 5.6e-33
HKLHMJLG_03938 6.6e-69 yxiG
HKLHMJLG_03939 2.3e-61 yxxG
HKLHMJLG_03941 1.9e-08
HKLHMJLG_03942 8.5e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
HKLHMJLG_03943 2.3e-146 yxxF EG EamA-like transporter family
HKLHMJLG_03944 9.8e-74 yxiE T Belongs to the universal stress protein A family
HKLHMJLG_03945 1.2e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLHMJLG_03946 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKLHMJLG_03947 0.0 L HKD family nuclease
HKLHMJLG_03948 6.5e-66 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HKLHMJLG_03949 1.6e-279 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HKLHMJLG_03950 3.8e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HKLHMJLG_03951 5.1e-287 hutH 4.3.1.3 E Histidine ammonia-lyase
HKLHMJLG_03952 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HKLHMJLG_03953 3.6e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HKLHMJLG_03954 5.9e-177 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HKLHMJLG_03955 2e-253 lysP E amino acid
HKLHMJLG_03956 5.1e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HKLHMJLG_03957 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKLHMJLG_03958 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKLHMJLG_03959 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HKLHMJLG_03960 4e-150 yidA S hydrolases of the HAD superfamily
HKLHMJLG_03963 6.4e-13 yxeE
HKLHMJLG_03964 8.4e-23 yxeD
HKLHMJLG_03965 3.8e-15
HKLHMJLG_03966 1.8e-178 fhuD P Periplasmic binding protein
HKLHMJLG_03967 5e-57 yxeA S Protein of unknown function (DUF1093)
HKLHMJLG_03968 0.0 yxdM V ABC transporter (permease)
HKLHMJLG_03969 6.7e-139 yxdL V ABC transporter, ATP-binding protein
HKLHMJLG_03970 3.2e-178 T PhoQ Sensor
HKLHMJLG_03971 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_03972 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HKLHMJLG_03973 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HKLHMJLG_03974 1.1e-166 iolH G Xylose isomerase-like TIM barrel
HKLHMJLG_03975 5.6e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HKLHMJLG_03976 1.2e-233 iolF EGP Major facilitator Superfamily
HKLHMJLG_03977 1.2e-176 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HKLHMJLG_03978 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HKLHMJLG_03979 6.8e-184 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HKLHMJLG_03980 1.7e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HKLHMJLG_03981 2.1e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKLHMJLG_03982 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
HKLHMJLG_03983 4.9e-176 iolS C Aldo keto reductase
HKLHMJLG_03984 6.7e-246 csbC EGP Major facilitator Superfamily
HKLHMJLG_03985 0.0 htpG O Molecular chaperone. Has ATPase activity
HKLHMJLG_03987 4.8e-151 IQ Enoyl-(Acyl carrier protein) reductase
HKLHMJLG_03988 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKLHMJLG_03989 2.4e-201 desK 2.7.13.3 T Histidine kinase
HKLHMJLG_03990 3.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HKLHMJLG_03991 8.9e-220 yxbF K Bacterial regulatory proteins, tetR family
HKLHMJLG_03992 7.3e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HKLHMJLG_03993 6.8e-141 S PQQ-like domain
HKLHMJLG_03994 6e-65 S Family of unknown function (DUF5391)
HKLHMJLG_03995 1.5e-49 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHMJLG_03996 9e-204 EGP Major facilitator Superfamily
HKLHMJLG_03997 1.5e-74 yxaI S membrane protein domain
HKLHMJLG_03998 8.1e-128 E Ring-cleavage extradiol dioxygenase
HKLHMJLG_03999 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HKLHMJLG_04000 2.3e-287 ahpF O Alkyl hydroperoxide reductase
HKLHMJLG_04001 3.8e-229 XK27_00240 S Fic/DOC family
HKLHMJLG_04002 1.9e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
HKLHMJLG_04003 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HKLHMJLG_04004 1.5e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HKLHMJLG_04005 1.9e-155 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HKLHMJLG_04006 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HKLHMJLG_04007 4.8e-95 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HKLHMJLG_04008 4.6e-188 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HKLHMJLG_04009 2e-183 S Fusaric acid resistance protein-like
HKLHMJLG_04010 2.1e-17
HKLHMJLG_04011 2.6e-35 L HNH nucleases
HKLHMJLG_04012 3.3e-67 L AAA ATPase domain
HKLHMJLG_04013 2.8e-265 S AIPR protein
HKLHMJLG_04014 2.9e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKLHMJLG_04015 7.9e-08 S YyzF-like protein
HKLHMJLG_04017 1.6e-216 yycP
HKLHMJLG_04018 1e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKLHMJLG_04019 9.6e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
HKLHMJLG_04020 2.6e-85 yycN 2.3.1.128 K Acetyltransferase
HKLHMJLG_04022 2.4e-201 S Histidine kinase
HKLHMJLG_04023 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HKLHMJLG_04024 1.2e-258 rocE E amino acid
HKLHMJLG_04025 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HKLHMJLG_04026 4.2e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HKLHMJLG_04027 2.2e-42 sdpR K transcriptional
HKLHMJLG_04028 1.2e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HKLHMJLG_04029 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
HKLHMJLG_04030 8.8e-306 S ABC transporter
HKLHMJLG_04031 7.6e-198 S Major Facilitator Superfamily
HKLHMJLG_04032 6.3e-262
HKLHMJLG_04033 1.5e-191 2.7.7.73, 2.7.7.80 H ThiF family
HKLHMJLG_04034 4.7e-255 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKLHMJLG_04035 9.4e-11 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_04036 2.4e-220 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKLHMJLG_04037 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HKLHMJLG_04038 2.6e-152 yycI S protein conserved in bacteria
HKLHMJLG_04039 4.2e-261 yycH S protein conserved in bacteria
HKLHMJLG_04040 0.0 vicK 2.7.13.3 T Histidine kinase
HKLHMJLG_04041 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLHMJLG_04046 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKLHMJLG_04047 5e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKLHMJLG_04048 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HKLHMJLG_04049 8e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HKLHMJLG_04051 4.6e-17 yycC K YycC-like protein
HKLHMJLG_04052 7.1e-242 M Glycosyltransferase Family 4
HKLHMJLG_04053 4.3e-205 S Ecdysteroid kinase
HKLHMJLG_04054 2.4e-236 S Carbamoyl-phosphate synthase L chain, ATP binding domain
HKLHMJLG_04055 7.3e-250 M Glycosyltransferase Family 4
HKLHMJLG_04056 9.8e-123 S GlcNAc-PI de-N-acetylase
HKLHMJLG_04057 1.2e-123 KLT COG0515 Serine threonine protein kinase
HKLHMJLG_04058 4.9e-73 rplI J binds to the 23S rRNA
HKLHMJLG_04059 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HKLHMJLG_04060 1.6e-158 yybS S membrane
HKLHMJLG_04062 6.5e-85 cotF M Spore coat protein
HKLHMJLG_04063 6.2e-66 ydeP3 K Transcriptional regulator
HKLHMJLG_04064 1.9e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HKLHMJLG_04065 4.8e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKLHMJLG_04066 7.7e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HKLHMJLG_04067 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HKLHMJLG_04068 9e-116 K FCD domain
HKLHMJLG_04069 1.3e-77 dinB S PFAM DinB family protein
HKLHMJLG_04070 2.6e-161 G Major Facilitator Superfamily
HKLHMJLG_04071 2.2e-162 yfiE K LysR substrate binding domain
HKLHMJLG_04072 1.1e-100 E LysE type translocator
HKLHMJLG_04073 1.5e-92 ynfM EGP Major facilitator Superfamily
HKLHMJLG_04074 1e-111 ynfM EGP Major facilitator Superfamily
HKLHMJLG_04075 1.3e-165 gltC K Transcriptional regulator
HKLHMJLG_04076 1.4e-54 ypaA S Protein of unknown function (DUF1304)
HKLHMJLG_04077 9.6e-115 drgA C nitroreductase
HKLHMJLG_04078 3.2e-69 ydgJ K Winged helix DNA-binding domain
HKLHMJLG_04079 3.8e-154 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HKLHMJLG_04080 2.5e-77 yybA 2.3.1.57 K transcriptional
HKLHMJLG_04081 7.7e-76 yjcF S Acetyltransferase (GNAT) domain
HKLHMJLG_04082 2.3e-164 eaeH M Domain of Unknown Function (DUF1259)
HKLHMJLG_04083 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
HKLHMJLG_04084 4.9e-165 K Transcriptional regulator
HKLHMJLG_04085 8.5e-126 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HKLHMJLG_04086 4.4e-100
HKLHMJLG_04087 5.4e-41 qacC U Small Multidrug Resistance protein
HKLHMJLG_04088 1.1e-248 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKLHMJLG_04089 6.1e-131 ydfC EG EamA-like transporter family
HKLHMJLG_04090 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HKLHMJLG_04091 9.2e-164 yyaK S CAAX protease self-immunity
HKLHMJLG_04092 6.2e-249 ydjK G Sugar (and other) transporter
HKLHMJLG_04093 5.8e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKLHMJLG_04094 4.8e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HKLHMJLG_04095 7.3e-146 xth 3.1.11.2 L exodeoxyribonuclease III
HKLHMJLG_04096 3.6e-102 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKLHMJLG_04097 2.7e-108 adaA 3.2.2.21 K Transcriptional regulator
HKLHMJLG_04098 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKLHMJLG_04099 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKLHMJLG_04100 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HKLHMJLG_04101 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKLHMJLG_04102 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKLHMJLG_04103 7.8e-34 yyzM S protein conserved in bacteria
HKLHMJLG_04104 2.4e-176 yyaD S Membrane
HKLHMJLG_04105 3.4e-83 4.2.1.103 K FR47-like protein
HKLHMJLG_04106 6.2e-111 yyaC S Sporulation protein YyaC
HKLHMJLG_04107 1.6e-149 spo0J K Belongs to the ParB family
HKLHMJLG_04108 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
HKLHMJLG_04109 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HKLHMJLG_04110 3.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HKLHMJLG_04111 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKLHMJLG_04112 2.6e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKLHMJLG_04113 7.1e-110 jag S single-stranded nucleic acid binding R3H
HKLHMJLG_04114 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKLHMJLG_04115 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)