ORF_ID e_value Gene_name EC_number CAZy COGs Description
HOIIOEIH_00008 2.8e-48 S dUTPase
HOIIOEIH_00010 9.9e-97 ydiP 2.1.1.37 H C-5 cytosine-specific DNA methylase
HOIIOEIH_00011 9.1e-126 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HOIIOEIH_00014 4.2e-27 yqaO S Phage-like element PBSX protein XtrA
HOIIOEIH_00016 1e-54 S Protein of unknown function (DUF1064)
HOIIOEIH_00017 6.4e-22 S YopX protein
HOIIOEIH_00020 7.6e-130 xkdC L IstB-like ATP binding protein
HOIIOEIH_00021 1.5e-36 3.1.3.16 L DnaD domain protein
HOIIOEIH_00022 8.4e-135 recT L RecT family
HOIIOEIH_00023 1.6e-153 yqaJ L YqaJ-like viral recombinase domain
HOIIOEIH_00029 1.3e-86
HOIIOEIH_00030 5.2e-67 S DNA binding
HOIIOEIH_00031 5.8e-15 S Helix-turn-helix domain
HOIIOEIH_00032 8.4e-13 K Helix-turn-helix domain
HOIIOEIH_00033 2.1e-16 xre K Helix-turn-helix XRE-family like proteins
HOIIOEIH_00034 3.3e-49
HOIIOEIH_00035 4.7e-23 S Protein of unknown function (DUF4064)
HOIIOEIH_00036 2.5e-49 xkdA E IrrE N-terminal-like domain
HOIIOEIH_00037 1.6e-166 L Belongs to the 'phage' integrase family
HOIIOEIH_00039 1.6e-130 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HOIIOEIH_00040 3.1e-188 yubA S transporter activity
HOIIOEIH_00041 2e-175 ygjR S Oxidoreductase
HOIIOEIH_00042 1.2e-246 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HOIIOEIH_00043 1.5e-52 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HOIIOEIH_00044 5.2e-265 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HOIIOEIH_00045 6.1e-132 fucR K COG1349 Transcriptional regulators of sugar metabolism
HOIIOEIH_00046 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HOIIOEIH_00047 6.4e-226 mcpA NT chemotaxis protein
HOIIOEIH_00048 2.3e-284 mcpA NT chemotaxis protein
HOIIOEIH_00049 4.9e-210 mcpA NT chemotaxis protein
HOIIOEIH_00050 4.5e-211 mcpA NT chemotaxis protein
HOIIOEIH_00051 6.9e-133 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HOIIOEIH_00052 6.1e-36
HOIIOEIH_00053 8.1e-164 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HOIIOEIH_00054 1.2e-67 yugU S Uncharacterised protein family UPF0047
HOIIOEIH_00055 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HOIIOEIH_00056 7.9e-233 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HOIIOEIH_00057 1.2e-115 yugP S Zn-dependent protease
HOIIOEIH_00058 1.4e-35
HOIIOEIH_00059 1.2e-52 mstX S Membrane-integrating protein Mistic
HOIIOEIH_00060 3.5e-172 yugO P COG1226 Kef-type K transport systems
HOIIOEIH_00061 2.3e-69 yugN S YugN-like family
HOIIOEIH_00063 1.2e-260 pgi 5.3.1.9 G Belongs to the GPI family
HOIIOEIH_00064 5.5e-225 yugK C Dehydrogenase
HOIIOEIH_00065 8.4e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HOIIOEIH_00066 1.1e-34 yuzA S Domain of unknown function (DUF378)
HOIIOEIH_00067 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HOIIOEIH_00068 9e-198 yugH 2.6.1.1 E Aminotransferase
HOIIOEIH_00069 4.7e-85 alaR K Transcriptional regulator
HOIIOEIH_00070 5.3e-150 yugF I Hydrolase
HOIIOEIH_00071 1.7e-38 yugE S Domain of unknown function (DUF1871)
HOIIOEIH_00072 4e-220 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HOIIOEIH_00073 4.3e-223 T PhoQ Sensor
HOIIOEIH_00074 4.1e-68 kapB G Kinase associated protein B
HOIIOEIH_00075 5.1e-113 kapD L the KinA pathway to sporulation
HOIIOEIH_00076 1.3e-164 yuxJ EGP Major facilitator Superfamily
HOIIOEIH_00077 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HOIIOEIH_00078 1.9e-71 yuxK S protein conserved in bacteria
HOIIOEIH_00079 1.2e-76 yufK S Family of unknown function (DUF5366)
HOIIOEIH_00080 5.3e-287 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HOIIOEIH_00081 1.2e-123 dcuR T COG4565 Response regulator of citrate malate metabolism
HOIIOEIH_00082 1.2e-186 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HOIIOEIH_00083 5.6e-262 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HOIIOEIH_00084 6.2e-180 yufP S Belongs to the binding-protein-dependent transport system permease family
HOIIOEIH_00085 4.3e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
HOIIOEIH_00086 2.7e-228 maeN C COG3493 Na citrate symporter
HOIIOEIH_00087 5.5e-14
HOIIOEIH_00088 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HOIIOEIH_00089 5.9e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HOIIOEIH_00090 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HOIIOEIH_00091 2.8e-258 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HOIIOEIH_00092 2.3e-73 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HOIIOEIH_00093 1.2e-37 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HOIIOEIH_00094 1.3e-55 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HOIIOEIH_00095 5.1e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HOIIOEIH_00096 8.7e-78 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOIIOEIH_00097 1.2e-21 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOIIOEIH_00098 0.0 comP 2.7.13.3 T Histidine kinase
HOIIOEIH_00100 8.6e-147 comQ H Polyprenyl synthetase
HOIIOEIH_00102 4.1e-22 yuzC
HOIIOEIH_00103 1.2e-227 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HOIIOEIH_00104 1.2e-277 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOIIOEIH_00105 1e-101 pncA Q COG1335 Amidases related to nicotinamidase
HOIIOEIH_00106 7.9e-59 yueI S Protein of unknown function (DUF1694)
HOIIOEIH_00107 1.4e-37 yueH S YueH-like protein
HOIIOEIH_00108 3.8e-26 yueG S Spore germination protein gerPA/gerPF
HOIIOEIH_00109 5.1e-188 yueF S transporter activity
HOIIOEIH_00110 3.6e-36 S Protein of unknown function (DUF2283)
HOIIOEIH_00111 6.4e-24 S Protein of unknown function (DUF2642)
HOIIOEIH_00112 3.1e-95 yueE S phosphohydrolase
HOIIOEIH_00113 1.7e-123 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOIIOEIH_00114 6.2e-63 yueC S Family of unknown function (DUF5383)
HOIIOEIH_00115 0.0 esaA S type VII secretion protein EsaA
HOIIOEIH_00116 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HOIIOEIH_00117 4.2e-189 essB S WXG100 protein secretion system (Wss), protein YukC
HOIIOEIH_00118 6.3e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
HOIIOEIH_00119 2.8e-45 esxA S Belongs to the WXG100 family
HOIIOEIH_00120 1e-221 yukF QT Transcriptional regulator
HOIIOEIH_00121 2.4e-201 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HOIIOEIH_00122 1.6e-128 yukJ S Uncharacterized conserved protein (DUF2278)
HOIIOEIH_00123 6.5e-36 mbtH S MbtH-like protein
HOIIOEIH_00124 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOIIOEIH_00125 1.7e-168 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HOIIOEIH_00126 2e-302 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HOIIOEIH_00127 1.1e-209 entC 5.4.4.2 HQ Isochorismate synthase
HOIIOEIH_00128 1.6e-135 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_00129 9.3e-153 besA S Putative esterase
HOIIOEIH_00130 4.7e-116 yuiH S Oxidoreductase molybdopterin binding domain
HOIIOEIH_00131 9.4e-96 bioY S Biotin biosynthesis protein
HOIIOEIH_00132 2.1e-201 yuiF S antiporter
HOIIOEIH_00133 9e-273 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HOIIOEIH_00134 5.5e-75 yuiD S protein conserved in bacteria
HOIIOEIH_00135 3.2e-113 yuiC S protein conserved in bacteria
HOIIOEIH_00136 6e-25 yuiB S Putative membrane protein
HOIIOEIH_00137 3e-234 yumB 1.6.99.3 C NADH dehydrogenase
HOIIOEIH_00138 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HOIIOEIH_00140 2.1e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HOIIOEIH_00141 5.7e-112 paiB K Putative FMN-binding domain
HOIIOEIH_00142 2.5e-81 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOIIOEIH_00143 5.9e-61 erpA S Belongs to the HesB IscA family
HOIIOEIH_00144 2.2e-159 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HOIIOEIH_00145 9.4e-196 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HOIIOEIH_00146 3.2e-39 yuzB S Belongs to the UPF0349 family
HOIIOEIH_00147 2.5e-197 yutJ 1.6.99.3 C NADH dehydrogenase
HOIIOEIH_00148 7e-53 yuzD S protein conserved in bacteria
HOIIOEIH_00149 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HOIIOEIH_00150 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HOIIOEIH_00151 2.8e-171 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HOIIOEIH_00152 6.3e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HOIIOEIH_00153 3e-240 hom 1.1.1.3 E homoserine dehydrogenase
HOIIOEIH_00154 1.3e-179 yutH S Spore coat protein
HOIIOEIH_00155 1.8e-75 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HOIIOEIH_00156 1.9e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HOIIOEIH_00157 1.5e-66 yutE S Protein of unknown function DUF86
HOIIOEIH_00158 9.7e-48 yutD S protein conserved in bacteria
HOIIOEIH_00159 4e-105 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HOIIOEIH_00160 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HOIIOEIH_00161 4.2e-194 lytH M Peptidase, M23
HOIIOEIH_00162 5.4e-128 yunB S Sporulation protein YunB (Spo_YunB)
HOIIOEIH_00163 4.1e-47 yunC S Domain of unknown function (DUF1805)
HOIIOEIH_00164 3.2e-256 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HOIIOEIH_00165 8.8e-137 yunE S membrane transporter protein
HOIIOEIH_00166 1.2e-168 yunF S Protein of unknown function DUF72
HOIIOEIH_00167 2.2e-57 yunG
HOIIOEIH_00168 2.7e-244 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HOIIOEIH_00169 2.3e-295 pucR QT COG2508 Regulator of polyketide synthase expression
HOIIOEIH_00170 5.3e-224 pbuX F Permease family
HOIIOEIH_00171 3e-216 pbuX F xanthine
HOIIOEIH_00172 4.3e-259 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HOIIOEIH_00173 5.9e-50 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HOIIOEIH_00175 1.8e-87 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HOIIOEIH_00176 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HOIIOEIH_00177 5.2e-129 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HOIIOEIH_00178 6.7e-97 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HOIIOEIH_00179 1.9e-170 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HOIIOEIH_00180 2.2e-232 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HOIIOEIH_00181 1.3e-229 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HOIIOEIH_00182 2.1e-23 2.4.2.18 E Anthranilate phosphoribosyltransferase
HOIIOEIH_00183 7e-161 bsn L Ribonuclease
HOIIOEIH_00184 1.2e-192 msmX P Belongs to the ABC transporter superfamily
HOIIOEIH_00185 4.4e-132 yurK K UTRA
HOIIOEIH_00186 3.3e-155 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HOIIOEIH_00187 9.9e-166 yurM P COG0395 ABC-type sugar transport system, permease component
HOIIOEIH_00188 2e-155 yurN G Binding-protein-dependent transport system inner membrane component
HOIIOEIH_00189 1.7e-232 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HOIIOEIH_00190 8.2e-182 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HOIIOEIH_00191 1.6e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HOIIOEIH_00192 3e-196 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HOIIOEIH_00194 1.3e-33
HOIIOEIH_00195 3.2e-65 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOIIOEIH_00196 3.5e-271 sufB O FeS cluster assembly
HOIIOEIH_00197 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HOIIOEIH_00198 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HOIIOEIH_00199 1.9e-242 sufD O assembly protein SufD
HOIIOEIH_00200 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HOIIOEIH_00201 4.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HOIIOEIH_00202 1.5e-144 metQ P Belongs to the NlpA lipoprotein family
HOIIOEIH_00203 3.4e-94 metI P COG2011 ABC-type metal ion transport system, permease component
HOIIOEIH_00204 1.1e-181 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOIIOEIH_00205 1e-54 yusD S SCP-2 sterol transfer family
HOIIOEIH_00206 8.9e-53 traF CO Thioredoxin
HOIIOEIH_00207 1.5e-71 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HOIIOEIH_00208 3e-37 yusG S Protein of unknown function (DUF2553)
HOIIOEIH_00209 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HOIIOEIH_00210 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HOIIOEIH_00211 2.5e-306 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HOIIOEIH_00212 1.8e-215 fadA 2.3.1.16 I Belongs to the thiolase family
HOIIOEIH_00213 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HOIIOEIH_00214 8.1e-09 S YuzL-like protein
HOIIOEIH_00215 8.1e-160 fadM E Proline dehydrogenase
HOIIOEIH_00216 5.6e-39
HOIIOEIH_00217 5.4e-53 yusN M Coat F domain
HOIIOEIH_00218 8.2e-71 yusO K Iron dependent repressor, N-terminal DNA binding domain
HOIIOEIH_00219 5e-285 yusP P Major facilitator superfamily
HOIIOEIH_00220 3.3e-62 yusQ S Tautomerase enzyme
HOIIOEIH_00221 1.1e-109 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_00222 6.8e-151 yusT K LysR substrate binding domain
HOIIOEIH_00223 3.3e-46 yusU S Protein of unknown function (DUF2573)
HOIIOEIH_00224 1.1e-152 yusV 3.6.3.34 HP ABC transporter
HOIIOEIH_00225 3.1e-64 S YusW-like protein
HOIIOEIH_00226 8.8e-299 pepF2 E COG1164 Oligoendopeptidase F
HOIIOEIH_00227 8.2e-146 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_00228 1.8e-78 dps P Ferritin-like domain
HOIIOEIH_00229 4.5e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HOIIOEIH_00230 3.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_00231 5e-246 cssS 2.7.13.3 T PhoQ Sensor
HOIIOEIH_00232 3.4e-155 yuxN K Transcriptional regulator
HOIIOEIH_00233 3.6e-260 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HOIIOEIH_00234 2.3e-24 S Protein of unknown function (DUF3970)
HOIIOEIH_00235 6.3e-239 gerAA EG Spore germination protein
HOIIOEIH_00236 1.5e-192 gerAB E Spore germination protein
HOIIOEIH_00237 1.2e-173 gerAC S Spore germination B3/ GerAC like, C-terminal
HOIIOEIH_00238 4.3e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOIIOEIH_00239 1.5e-181 vraS 2.7.13.3 T Histidine kinase
HOIIOEIH_00240 3.5e-121 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HOIIOEIH_00241 8.5e-106 liaG S Putative adhesin
HOIIOEIH_00242 2.9e-101 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HOIIOEIH_00243 2.1e-61 liaI S membrane
HOIIOEIH_00244 5e-224 yvqJ EGP Major facilitator Superfamily
HOIIOEIH_00245 2.8e-94 yvqK 2.5.1.17 S Adenosyltransferase
HOIIOEIH_00246 1.8e-219 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HOIIOEIH_00247 2.3e-177 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_00248 5.3e-162 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HOIIOEIH_00249 1.1e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_00250 6.9e-164 yvrE G SMP-30/Gluconolaconase/LRE-like region
HOIIOEIH_00251 0.0 T PhoQ Sensor
HOIIOEIH_00252 1.1e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_00253 2.7e-22
HOIIOEIH_00254 3e-99 yvrI K RNA polymerase
HOIIOEIH_00255 5e-17 S YvrJ protein family
HOIIOEIH_00256 1.8e-220 oxdC 4.1.1.2 G Oxalate decarboxylase
HOIIOEIH_00257 4.6e-54 yvrL S Regulatory protein YrvL
HOIIOEIH_00258 2.5e-204 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HOIIOEIH_00259 3e-122 macB V ABC transporter, ATP-binding protein
HOIIOEIH_00260 1.9e-169 M Efflux transporter rnd family, mfp subunit
HOIIOEIH_00261 3.9e-145 fhuC 3.6.3.34 HP ABC transporter
HOIIOEIH_00262 8.7e-171 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_00263 2.7e-190 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_00264 1.1e-156 fhuD P ABC transporter
HOIIOEIH_00266 6.8e-230 yvsH E Arginine ornithine antiporter
HOIIOEIH_00267 1.5e-15 S Small spore protein J (Spore_SspJ)
HOIIOEIH_00268 9.5e-83 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HOIIOEIH_00269 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HOIIOEIH_00270 8.1e-163 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HOIIOEIH_00271 3.6e-132 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HOIIOEIH_00272 1.2e-115 modB P COG4149 ABC-type molybdate transport system, permease component
HOIIOEIH_00273 9.4e-155 yvgN S reductase
HOIIOEIH_00274 1.5e-83 yvgO
HOIIOEIH_00275 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HOIIOEIH_00276 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HOIIOEIH_00277 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HOIIOEIH_00278 0.0 helD 3.6.4.12 L DNA helicase
HOIIOEIH_00279 7e-107 yvgT S membrane
HOIIOEIH_00280 6.5e-72 bdbC O Required for disulfide bond formation in some proteins
HOIIOEIH_00281 3.1e-100 bdbD O Thioredoxin
HOIIOEIH_00282 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HOIIOEIH_00283 0.0 copA 3.6.3.54 P P-type ATPase
HOIIOEIH_00284 1.7e-28 copZ P Copper resistance protein CopZ
HOIIOEIH_00285 6.3e-48 csoR S transcriptional
HOIIOEIH_00286 1.2e-186 yvaA 1.1.1.371 S Oxidoreductase
HOIIOEIH_00287 1e-116 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HOIIOEIH_00288 0.0 yvaC S Fusaric acid resistance protein-like
HOIIOEIH_00289 8.1e-101 K FCD domain
HOIIOEIH_00290 7.2e-143 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HOIIOEIH_00291 6.5e-69 yvaD S Family of unknown function (DUF5360)
HOIIOEIH_00292 2e-53 yvaE P Small Multidrug Resistance protein
HOIIOEIH_00293 2.7e-92 K Bacterial regulatory proteins, tetR family
HOIIOEIH_00294 1.3e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_00296 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HOIIOEIH_00297 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HOIIOEIH_00298 1.2e-140 est 3.1.1.1 S Carboxylesterase
HOIIOEIH_00299 2.4e-23 secG U Preprotein translocase subunit SecG
HOIIOEIH_00300 4.5e-135 yvaM S Serine aminopeptidase, S33
HOIIOEIH_00301 9.8e-36 yvzC K Transcriptional
HOIIOEIH_00302 1.2e-68 K transcriptional
HOIIOEIH_00303 1.1e-66 yvaO K Cro/C1-type HTH DNA-binding domain
HOIIOEIH_00304 4.8e-54 yodB K transcriptional
HOIIOEIH_00305 4.8e-206 NT chemotaxis protein
HOIIOEIH_00306 1.3e-153 T His Kinase A (phosphoacceptor) domain
HOIIOEIH_00307 6.4e-106 K Transcriptional regulatory protein, C terminal
HOIIOEIH_00308 1.5e-82 mutG S ABC-2 family transporter protein
HOIIOEIH_00309 5e-86 spaE S ABC-2 family transporter protein
HOIIOEIH_00310 1.9e-103 mutF V ABC transporter, ATP-binding protein
HOIIOEIH_00313 8.3e-101 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HOIIOEIH_00314 9.1e-167 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HOIIOEIH_00315 4e-108 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HOIIOEIH_00316 1.2e-208 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HOIIOEIH_00317 1.3e-85 yvbF K Belongs to the GbsR family
HOIIOEIH_00318 6.6e-43 L COG2963 Transposase and inactivated derivatives
HOIIOEIH_00319 8.6e-128 L Molecular Function DNA binding, Biological Process DNA recombination
HOIIOEIH_00320 5.9e-107 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HOIIOEIH_00321 3.1e-167 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HOIIOEIH_00322 6.6e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HOIIOEIH_00323 5e-207 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HOIIOEIH_00324 1e-96 yvbF K Belongs to the GbsR family
HOIIOEIH_00325 1.1e-27 yvbH S YvbH-like oligomerisation region
HOIIOEIH_00326 1e-114 exoY M Membrane
HOIIOEIH_00327 0.0 tcaA S response to antibiotic
HOIIOEIH_00328 1.8e-75 yvbK 3.1.3.25 K acetyltransferase
HOIIOEIH_00329 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOIIOEIH_00330 1.1e-294 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HOIIOEIH_00331 3.6e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HOIIOEIH_00332 2.5e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HOIIOEIH_00333 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOIIOEIH_00334 2.4e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HOIIOEIH_00335 1.1e-248 araE EGP Major facilitator Superfamily
HOIIOEIH_00336 2.5e-200 araR K transcriptional
HOIIOEIH_00337 4e-37 S PFAM Archaeal ATPase
HOIIOEIH_00338 3.3e-186 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOIIOEIH_00339 2.3e-151 yvbU K Transcriptional regulator
HOIIOEIH_00340 1e-149 yvbV EG EamA-like transporter family
HOIIOEIH_00341 1.2e-223 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HOIIOEIH_00342 5.1e-174 yvbX S Glycosyl hydrolase
HOIIOEIH_00343 1.2e-129 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HOIIOEIH_00344 2.8e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HOIIOEIH_00345 3e-133 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HOIIOEIH_00346 6.3e-47 S Protein of unknown function (DUF2812)
HOIIOEIH_00347 2.6e-31 K Transcriptional regulator PadR-like family
HOIIOEIH_00348 1.4e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOIIOEIH_00349 1.1e-177 desK 2.7.13.3 T Histidine kinase
HOIIOEIH_00350 5.5e-130 yvfS V COG0842 ABC-type multidrug transport system, permease component
HOIIOEIH_00351 2.4e-151 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HOIIOEIH_00352 1.7e-145 rsbQ S Alpha/beta hydrolase family
HOIIOEIH_00353 9.5e-172 rsbU 3.1.3.3 T response regulator
HOIIOEIH_00354 3.8e-235 galA 3.2.1.89 G arabinogalactan
HOIIOEIH_00355 0.0 lacA 3.2.1.23 G beta-galactosidase
HOIIOEIH_00356 6.7e-148 ganQ P transport
HOIIOEIH_00357 5.1e-229 malC P COG1175 ABC-type sugar transport systems, permease components
HOIIOEIH_00358 2.3e-221 cycB G COG2182 Maltose-binding periplasmic proteins domains
HOIIOEIH_00359 1.3e-179 lacR K Transcriptional regulator
HOIIOEIH_00360 3.7e-115 yvfI K COG2186 Transcriptional regulators
HOIIOEIH_00361 3.6e-302 yvfH C L-lactate permease
HOIIOEIH_00362 2.2e-235 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HOIIOEIH_00363 1e-31 yvfG S YvfG protein
HOIIOEIH_00364 5.8e-180 yvfF GM Exopolysaccharide biosynthesis protein
HOIIOEIH_00365 2.2e-210 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HOIIOEIH_00366 5.9e-48 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HOIIOEIH_00367 2e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HOIIOEIH_00368 3.5e-248 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOIIOEIH_00369 3.3e-181 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HOIIOEIH_00370 2.9e-196 epsI GM pyruvyl transferase
HOIIOEIH_00371 4e-179 epsH GT2 S Glycosyltransferase like family 2
HOIIOEIH_00372 2.1e-202 epsG S EpsG family
HOIIOEIH_00373 4.4e-203 epsF GT4 M Glycosyl transferases group 1
HOIIOEIH_00374 5.6e-155 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HOIIOEIH_00375 3.6e-205 epsD GT4 M Glycosyl transferase 4-like
HOIIOEIH_00376 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HOIIOEIH_00377 1.1e-113 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HOIIOEIH_00378 4.1e-119 ywqC M biosynthesis protein
HOIIOEIH_00379 5.3e-75 slr K transcriptional
HOIIOEIH_00380 1.4e-51 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HOIIOEIH_00381 2.1e-202 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HOIIOEIH_00383 5.1e-92 padC Q Phenolic acid decarboxylase
HOIIOEIH_00384 9e-75 MA20_18690 S Protein of unknown function (DUF3237)
HOIIOEIH_00385 1.6e-64 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HOIIOEIH_00386 2e-44 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HOIIOEIH_00387 3.1e-240 pbpE V Beta-lactamase
HOIIOEIH_00388 1.6e-70
HOIIOEIH_00389 1.9e-272 sacB 2.4.1.10 GH68 M levansucrase activity
HOIIOEIH_00390 2.9e-298 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HOIIOEIH_00391 5e-106 Q FtsX-like permease family
HOIIOEIH_00392 9.6e-82 V ATPases associated with a variety of cellular activities
HOIIOEIH_00393 8.1e-80 T Transcriptional regulatory protein, C terminal
HOIIOEIH_00394 4.5e-80 T Histidine kinase
HOIIOEIH_00395 2.8e-11 CO Vitamin k epoxide reductase
HOIIOEIH_00398 6.5e-18 O DSBA-like thioredoxin domain
HOIIOEIH_00400 2.5e-104 msbA9 V ABC transporter transmembrane region
HOIIOEIH_00403 1e-60 6.3.5.4 E TIGRFAM asparagine synthase (glutamine-hydrolyzing)
HOIIOEIH_00404 3.1e-08 E Transglutaminase-like superfamily
HOIIOEIH_00405 2.1e-07 S Coenzyme PQQ synthesis protein D (PqqD)
HOIIOEIH_00406 1.4e-21 dpiB 2.7.13.3 T Sensor_kinase_SpoOB-type, alpha-helical domain
HOIIOEIH_00407 4.6e-33 K LytTr DNA-binding domain
HOIIOEIH_00408 2.8e-285 yveA E amino acid
HOIIOEIH_00409 5.9e-103 yvdT K Transcriptional regulator
HOIIOEIH_00410 1.1e-50 ykkC P Small Multidrug Resistance protein
HOIIOEIH_00411 2.5e-47 sugE P Small Multidrug Resistance protein
HOIIOEIH_00412 3e-87 yvdQ S Protein of unknown function (DUF3231)
HOIIOEIH_00414 2.1e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOIIOEIH_00415 2.6e-102 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HOIIOEIH_00416 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HOIIOEIH_00417 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HOIIOEIH_00418 1.1e-137 malA S Protein of unknown function (DUF1189)
HOIIOEIH_00419 5.6e-147 malD P transport
HOIIOEIH_00420 1.4e-240 malC P COG1175 ABC-type sugar transport systems, permease components
HOIIOEIH_00421 1.3e-224 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HOIIOEIH_00422 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HOIIOEIH_00423 2e-169 yvdE K Transcriptional regulator
HOIIOEIH_00424 6.2e-105 yvdD 3.2.2.10 S Belongs to the LOG family
HOIIOEIH_00425 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HOIIOEIH_00426 7.5e-286 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HOIIOEIH_00427 5.9e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HOIIOEIH_00428 3.8e-179 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOIIOEIH_00429 0.0 V ABC transporter (permease)
HOIIOEIH_00430 3.7e-137 yvcR V ABC transporter, ATP-binding protein
HOIIOEIH_00431 1.5e-181 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HOIIOEIH_00432 1.2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_00433 6.7e-33
HOIIOEIH_00434 1.2e-129 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HOIIOEIH_00435 1.6e-36 crh G Phosphocarrier protein Chr
HOIIOEIH_00436 1.8e-170 whiA K May be required for sporulation
HOIIOEIH_00437 9.8e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HOIIOEIH_00438 1.2e-163 rapZ S Displays ATPase and GTPase activities
HOIIOEIH_00439 2.8e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HOIIOEIH_00440 5.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HOIIOEIH_00441 1.1e-94 usp CBM50 M protein conserved in bacteria
HOIIOEIH_00442 1.2e-274 S COG0457 FOG TPR repeat
HOIIOEIH_00443 0.0 msbA2 3.6.3.44 V ABC transporter
HOIIOEIH_00445 5.2e-265
HOIIOEIH_00446 5.8e-68
HOIIOEIH_00447 6.5e-108 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HOIIOEIH_00448 1.1e-133 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HOIIOEIH_00449 2.8e-126 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HOIIOEIH_00450 6e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOIIOEIH_00451 3.7e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HOIIOEIH_00452 9.9e-220 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HOIIOEIH_00453 1.3e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HOIIOEIH_00454 1.7e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HOIIOEIH_00455 2.9e-134 yvpB NU protein conserved in bacteria
HOIIOEIH_00456 1.3e-117 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HOIIOEIH_00457 9e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HOIIOEIH_00458 2.2e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HOIIOEIH_00459 1.4e-159 yvoD P COG0370 Fe2 transport system protein B
HOIIOEIH_00460 5e-145 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HOIIOEIH_00461 1.1e-167 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HOIIOEIH_00462 1.1e-212 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HOIIOEIH_00463 3.4e-124 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HOIIOEIH_00464 8.9e-125 yvoA K transcriptional
HOIIOEIH_00465 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HOIIOEIH_00466 1e-73 adcR K helix_turn_helix multiple antibiotic resistance protein
HOIIOEIH_00467 2.6e-222 cypX 1.14.15.13 C Cytochrome P450
HOIIOEIH_00468 3.4e-124 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HOIIOEIH_00469 4.1e-84 yvmB K helix_turn_helix multiple antibiotic resistance protein
HOIIOEIH_00470 3.5e-182 yvmA EGP Major facilitator Superfamily
HOIIOEIH_00471 1.2e-50 yvlD S Membrane
HOIIOEIH_00472 2.8e-25 pspB KT PspC domain
HOIIOEIH_00473 4e-161 yvlB S Putative adhesin
HOIIOEIH_00474 4.8e-46 yvlA
HOIIOEIH_00475 2.8e-32 yvkN
HOIIOEIH_00476 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HOIIOEIH_00477 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HOIIOEIH_00478 1.2e-30 csbA S protein conserved in bacteria
HOIIOEIH_00479 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HOIIOEIH_00480 1.4e-98 yvkB K Transcriptional regulator
HOIIOEIH_00481 3.1e-224 yvkA EGP Major facilitator Superfamily
HOIIOEIH_00482 1.9e-212 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HOIIOEIH_00483 5.3e-56 swrA S Swarming motility protein
HOIIOEIH_00484 1.9e-264 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HOIIOEIH_00485 1.1e-153 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HOIIOEIH_00486 1.8e-122 ftsE D cell division ATP-binding protein FtsE
HOIIOEIH_00487 2.3e-51 cccB C COG2010 Cytochrome c, mono- and diheme variants
HOIIOEIH_00488 6.2e-138 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HOIIOEIH_00489 1.1e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HOIIOEIH_00490 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HOIIOEIH_00491 1.6e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOIIOEIH_00492 6.6e-63
HOIIOEIH_00493 5.5e-08 fliT S bacterial-type flagellum organization
HOIIOEIH_00494 3e-66 fliS N flagellar protein FliS
HOIIOEIH_00495 3.1e-257 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HOIIOEIH_00496 4.9e-54 flaG N flagellar protein FlaG
HOIIOEIH_00497 3.6e-123 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HOIIOEIH_00498 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HOIIOEIH_00499 5.2e-72 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HOIIOEIH_00500 5e-46 yviE
HOIIOEIH_00501 1.3e-149 flgL N Belongs to the bacterial flagellin family
HOIIOEIH_00502 2.6e-259 flgK N flagellar hook-associated protein
HOIIOEIH_00503 2.1e-74 flgN NOU FlgN protein
HOIIOEIH_00504 4.4e-37 flgM KNU Negative regulator of flagellin synthesis
HOIIOEIH_00505 1.1e-69 yvyF S flagellar protein
HOIIOEIH_00506 6.8e-117 comFC S Phosphoribosyl transferase domain
HOIIOEIH_00507 6.6e-42 comFB S Late competence development protein ComFB
HOIIOEIH_00508 3e-238 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HOIIOEIH_00509 3.2e-150 degV S protein conserved in bacteria
HOIIOEIH_00510 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOIIOEIH_00511 1.5e-182 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HOIIOEIH_00512 1.9e-118 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HOIIOEIH_00513 2.7e-160 yvhJ K Transcriptional regulator
HOIIOEIH_00514 1.1e-179 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HOIIOEIH_00515 8.6e-226 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HOIIOEIH_00516 1.4e-141 tuaG GT2 M Glycosyltransferase like family 2
HOIIOEIH_00517 1.4e-100 tuaF M protein involved in exopolysaccharide biosynthesis
HOIIOEIH_00518 1e-252 tuaE M Teichuronic acid biosynthesis protein
HOIIOEIH_00519 5.5e-256 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HOIIOEIH_00520 1e-202 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HOIIOEIH_00521 8e-242 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOIIOEIH_00522 3.5e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HOIIOEIH_00523 1.9e-94 M Glycosyltransferase like family 2
HOIIOEIH_00524 2.6e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HOIIOEIH_00525 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HOIIOEIH_00526 1.2e-12
HOIIOEIH_00527 2.1e-155 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HOIIOEIH_00528 4.4e-211 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HOIIOEIH_00529 4.3e-89 M Glycosyltransferase like family 2
HOIIOEIH_00530 4.3e-97 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HOIIOEIH_00531 2.3e-20 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HOIIOEIH_00532 6.5e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HOIIOEIH_00533 5.8e-262 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HOIIOEIH_00534 7.7e-133 tagG GM Transport permease protein
HOIIOEIH_00535 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOIIOEIH_00536 2.2e-230 ggaA M Glycosyltransferase like family 2
HOIIOEIH_00537 5.3e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HOIIOEIH_00538 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HOIIOEIH_00539 1.3e-86 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HOIIOEIH_00540 5e-106 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HOIIOEIH_00541 1.5e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HOIIOEIH_00542 1.1e-147 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HOIIOEIH_00543 2.1e-91 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOIIOEIH_00544 5.7e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOIIOEIH_00545 7.8e-203 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HOIIOEIH_00546 1.9e-183 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HOIIOEIH_00547 7.4e-248 gerBA EG Spore germination protein
HOIIOEIH_00548 7.5e-192 gerBB E Spore germination protein
HOIIOEIH_00549 1e-204 gerAC S Spore germination protein
HOIIOEIH_00550 3.9e-246 ywtG EGP Major facilitator Superfamily
HOIIOEIH_00551 2e-164 ywtF K Transcriptional regulator
HOIIOEIH_00552 2.8e-154 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HOIIOEIH_00553 1.4e-231 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HOIIOEIH_00554 1.5e-19 ywtC
HOIIOEIH_00555 3.8e-215 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HOIIOEIH_00556 8.6e-70 pgsC S biosynthesis protein
HOIIOEIH_00557 6.7e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HOIIOEIH_00558 3.7e-166 rbsR K transcriptional
HOIIOEIH_00559 1.7e-154 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOIIOEIH_00560 1.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HOIIOEIH_00561 5.6e-267 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HOIIOEIH_00562 1.6e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
HOIIOEIH_00563 8.5e-157 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HOIIOEIH_00564 4.9e-10 batE T Sh3 type 3 domain protein
HOIIOEIH_00565 1.4e-60 batE T Sh3 type 3 domain protein
HOIIOEIH_00566 1.2e-46 ywsA S Protein of unknown function (DUF3892)
HOIIOEIH_00567 7.2e-92 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HOIIOEIH_00568 2.4e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HOIIOEIH_00569 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HOIIOEIH_00570 4.7e-144 alsR K LysR substrate binding domain
HOIIOEIH_00571 3.3e-200 cotH M Spore Coat
HOIIOEIH_00572 1.3e-12
HOIIOEIH_00573 3e-105 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HOIIOEIH_00574 5.7e-29 S Domain of unknown function (DUF4181)
HOIIOEIH_00575 1.3e-293 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HOIIOEIH_00576 1.2e-80 ywrC K Transcriptional regulator
HOIIOEIH_00577 1.6e-103 ywrB P Chromate transporter
HOIIOEIH_00578 1.7e-88 ywrA P COG2059 Chromate transport protein ChrA
HOIIOEIH_00580 6.3e-91 ywqN S NAD(P)H-dependent
HOIIOEIH_00581 4.1e-156 K Transcriptional regulator
HOIIOEIH_00582 4.1e-293 S Domain of unknown function
HOIIOEIH_00583 2.4e-79 K helix_turn_helix, arabinose operon control protein
HOIIOEIH_00584 2.9e-128 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HOIIOEIH_00585 5.5e-51
HOIIOEIH_00586 3.2e-105
HOIIOEIH_00588 0.0 ywqJ S Pre-toxin TG
HOIIOEIH_00589 1.3e-38 ywqI S Family of unknown function (DUF5344)
HOIIOEIH_00590 1.7e-22 S Domain of unknown function (DUF5082)
HOIIOEIH_00591 1.7e-238 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HOIIOEIH_00592 6.1e-124 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HOIIOEIH_00593 2.6e-113 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HOIIOEIH_00594 3.7e-110 ywqC M biosynthesis protein
HOIIOEIH_00595 3.5e-17
HOIIOEIH_00596 2.3e-298 ywqB S SWIM zinc finger
HOIIOEIH_00597 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HOIIOEIH_00598 1.2e-149 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HOIIOEIH_00599 1.6e-135 glcR K COG1349 Transcriptional regulators of sugar metabolism
HOIIOEIH_00600 9.2e-56 ssbB L Single-stranded DNA-binding protein
HOIIOEIH_00601 5.1e-63 ywpG
HOIIOEIH_00602 7.9e-65 ywpF S YwpF-like protein
HOIIOEIH_00603 9.7e-83 srtA 3.4.22.70 M Sortase family
HOIIOEIH_00604 0.0 M1-568 M cell wall anchor domain
HOIIOEIH_00605 1.1e-176 M1-574 T Transcriptional regulatory protein, C terminal
HOIIOEIH_00606 0.0 ywpD T PhoQ Sensor
HOIIOEIH_00607 7.1e-52 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HOIIOEIH_00608 7.1e-83 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HOIIOEIH_00609 7.2e-192 S aspartate phosphatase
HOIIOEIH_00610 6e-138 flhP N flagellar basal body
HOIIOEIH_00611 7.9e-122 flhO N flagellar basal body
HOIIOEIH_00612 3.9e-179 mbl D Rod shape-determining protein
HOIIOEIH_00613 3e-44 spoIIID K Stage III sporulation protein D
HOIIOEIH_00614 4.7e-70 ywoH K COG1846 Transcriptional regulators
HOIIOEIH_00615 1.1e-204 ywoG EGP Major facilitator Superfamily
HOIIOEIH_00616 5.1e-201 ywoF P Right handed beta helix region
HOIIOEIH_00617 1e-273 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HOIIOEIH_00618 5.7e-234 ywoD EGP Major facilitator superfamily
HOIIOEIH_00619 1.4e-101 phzA Q Isochorismatase family
HOIIOEIH_00620 1.5e-72
HOIIOEIH_00621 3.7e-224 amt P Ammonium transporter
HOIIOEIH_00622 1.6e-58 nrgB K Belongs to the P(II) protein family
HOIIOEIH_00623 1.6e-100 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HOIIOEIH_00624 2.3e-67 ywnJ S VanZ like family
HOIIOEIH_00625 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HOIIOEIH_00626 2.7e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HOIIOEIH_00627 1e-13 ywnC S Family of unknown function (DUF5362)
HOIIOEIH_00628 3.2e-192 spsF 2.5.1.56, 2.7.7.92 M NeuB family
HOIIOEIH_00629 1.6e-68 ywnF S Family of unknown function (DUF5392)
HOIIOEIH_00630 1.6e-274 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOIIOEIH_00631 1.8e-128 mta K transcriptional
HOIIOEIH_00632 2.5e-57 ywnC S Family of unknown function (DUF5362)
HOIIOEIH_00633 3.2e-110 ywnB S NAD(P)H-binding
HOIIOEIH_00634 4.1e-63 ywnA K Transcriptional regulator
HOIIOEIH_00635 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HOIIOEIH_00636 1.5e-59 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HOIIOEIH_00637 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HOIIOEIH_00638 1.5e-113 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HOIIOEIH_00639 1.6e-121 urtD S ATPases associated with a variety of cellular activities
HOIIOEIH_00640 2.8e-183 urtC E Belongs to the binding-protein-dependent transport system permease family
HOIIOEIH_00641 1e-146 urtB E Belongs to the binding-protein-dependent transport system permease family
HOIIOEIH_00642 4.1e-218 urtA E Receptor family ligand binding region
HOIIOEIH_00643 6.1e-09 csbD K CsbD-like
HOIIOEIH_00644 1.6e-77 ywmF S Peptidase M50
HOIIOEIH_00645 1.8e-103 S response regulator aspartate phosphatase
HOIIOEIH_00646 2.1e-188 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HOIIOEIH_00647 1.9e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HOIIOEIH_00649 1.2e-118 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HOIIOEIH_00650 6.9e-119 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HOIIOEIH_00651 1.2e-167 spoIID D Stage II sporulation protein D
HOIIOEIH_00652 6.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOIIOEIH_00653 9.3e-130 ywmB S TATA-box binding
HOIIOEIH_00654 3.7e-32 ywzB S membrane
HOIIOEIH_00655 1.8e-81 ywmA
HOIIOEIH_00656 8.8e-58 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HOIIOEIH_00657 8.6e-265 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HOIIOEIH_00658 9.5e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HOIIOEIH_00659 2.6e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HOIIOEIH_00660 8e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOIIOEIH_00661 7.3e-41 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HOIIOEIH_00662 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOIIOEIH_00663 6.6e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HOIIOEIH_00664 2.8e-61 atpI S ATP synthase
HOIIOEIH_00665 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HOIIOEIH_00666 1e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOIIOEIH_00667 1.5e-89 ywlG S Belongs to the UPF0340 family
HOIIOEIH_00668 4.9e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HOIIOEIH_00669 2.7e-71 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOIIOEIH_00670 7.1e-90 mntP P Probably functions as a manganese efflux pump
HOIIOEIH_00671 2.8e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HOIIOEIH_00672 4.3e-72 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HOIIOEIH_00673 1.3e-109 spoIIR S stage II sporulation protein R
HOIIOEIH_00674 9.1e-54 ywlA S Uncharacterised protein family (UPF0715)
HOIIOEIH_00676 1.9e-150 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HOIIOEIH_00677 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HOIIOEIH_00678 5e-66 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOIIOEIH_00679 2.4e-85 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HOIIOEIH_00680 1.1e-154 ywkB S Membrane transport protein
HOIIOEIH_00681 0.0 sfcA 1.1.1.38 C malic enzyme
HOIIOEIH_00682 5.5e-101 tdk 2.7.1.21 F thymidine kinase
HOIIOEIH_00683 1.1e-32 rpmE J Binds the 23S rRNA
HOIIOEIH_00684 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HOIIOEIH_00685 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HOIIOEIH_00686 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOIIOEIH_00687 1.4e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HOIIOEIH_00688 1.8e-156 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HOIIOEIH_00689 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HOIIOEIH_00690 1.1e-89 ywjG S Domain of unknown function (DUF2529)
HOIIOEIH_00691 4.5e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HOIIOEIH_00692 7e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HOIIOEIH_00693 1.8e-204 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HOIIOEIH_00694 0.0 fadF C COG0247 Fe-S oxidoreductase
HOIIOEIH_00695 4.2e-204 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HOIIOEIH_00696 1.8e-178 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HOIIOEIH_00697 1.8e-41 ywjC
HOIIOEIH_00698 2.4e-87 ywjB H RibD C-terminal domain
HOIIOEIH_00699 5.7e-305 ywjA V ABC transporter
HOIIOEIH_00700 1.9e-278 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOIIOEIH_00701 3.3e-91 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOIIOEIH_00702 9.7e-118 narI 1.7.5.1 C nitrate reductase, gamma
HOIIOEIH_00703 9.9e-92 narJ 1.7.5.1 C nitrate reductase
HOIIOEIH_00704 6.9e-294 narH 1.7.5.1 C Nitrate reductase, beta
HOIIOEIH_00705 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HOIIOEIH_00706 4.4e-80 arfM T cyclic nucleotide binding
HOIIOEIH_00707 3e-125 ywiC S YwiC-like protein
HOIIOEIH_00708 1.7e-128 fnr K helix_turn_helix, cAMP Regulatory protein
HOIIOEIH_00709 8.6e-210 narK P COG2223 Nitrate nitrite transporter
HOIIOEIH_00710 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HOIIOEIH_00711 1.8e-72 ywiB S protein conserved in bacteria
HOIIOEIH_00712 1e-07 S Bacteriocin subtilosin A
HOIIOEIH_00713 3e-267 C Fe-S oxidoreductases
HOIIOEIH_00715 1.3e-128 cbiO V ABC transporter
HOIIOEIH_00716 1.7e-222 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HOIIOEIH_00717 3.2e-196 2.7.1.26, 2.7.7.2 L Peptidase, M16
HOIIOEIH_00718 1.8e-221 L Peptidase, M16
HOIIOEIH_00720 5.1e-182 ywhK CO amine dehydrogenase activity
HOIIOEIH_00721 2.6e-78 S aspartate phosphatase
HOIIOEIH_00723 8.1e-10
HOIIOEIH_00724 1.7e-20
HOIIOEIH_00727 2e-59 V ATPases associated with a variety of cellular activities
HOIIOEIH_00729 3e-167 speB 3.5.3.11 E Belongs to the arginase family
HOIIOEIH_00730 9.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HOIIOEIH_00731 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HOIIOEIH_00732 4.9e-93 ywhD S YwhD family
HOIIOEIH_00733 4e-116 ywhC S Peptidase family M50
HOIIOEIH_00734 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HOIIOEIH_00735 1.5e-68 ywhA K Transcriptional regulator
HOIIOEIH_00736 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOIIOEIH_00737 1e-87 ywgA 2.1.1.72, 3.1.21.3
HOIIOEIH_00738 2.8e-254 ywfO S COG1078 HD superfamily phosphohydrolases
HOIIOEIH_00739 3.1e-36 ywzC S Belongs to the UPF0741 family
HOIIOEIH_00740 6.9e-107 rsfA_1
HOIIOEIH_00741 3.6e-152 ywfM EG EamA-like transporter family
HOIIOEIH_00742 1.7e-151 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HOIIOEIH_00743 2.7e-155 cysL K Transcriptional regulator
HOIIOEIH_00744 4e-173 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HOIIOEIH_00745 4.3e-146 ywfI C May function as heme-dependent peroxidase
HOIIOEIH_00746 3e-134 IQ Enoyl-(Acyl carrier protein) reductase
HOIIOEIH_00747 8.6e-226 ywfG 2.6.1.83 E Aminotransferase class I and II
HOIIOEIH_00748 1.3e-205 bacE EGP Major facilitator Superfamily
HOIIOEIH_00749 1.4e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HOIIOEIH_00750 1.8e-136 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOIIOEIH_00751 5.4e-135 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HOIIOEIH_00752 1.1e-110 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HOIIOEIH_00753 9.9e-193 ywfA EGP Major facilitator Superfamily
HOIIOEIH_00754 3.2e-256 lysP E amino acid
HOIIOEIH_00755 0.0 rocB E arginine degradation protein
HOIIOEIH_00756 1.2e-288 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HOIIOEIH_00757 2.7e-241 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HOIIOEIH_00758 2.9e-76
HOIIOEIH_00759 6.7e-86 spsL 5.1.3.13 M Spore Coat
HOIIOEIH_00760 1.4e-150 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HOIIOEIH_00761 8.2e-179 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOIIOEIH_00762 1.6e-134 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HOIIOEIH_00763 3.2e-165 spsG M Spore Coat
HOIIOEIH_00764 1.4e-117 spsF M Spore Coat
HOIIOEIH_00765 5.1e-204 spsE 2.5.1.56 M acid synthase
HOIIOEIH_00766 4.7e-157 spsD 2.3.1.210 K Spore Coat
HOIIOEIH_00767 3e-215 spsC E Belongs to the DegT DnrJ EryC1 family
HOIIOEIH_00768 7.8e-255 spsB M Capsule polysaccharide biosynthesis protein
HOIIOEIH_00769 2.5e-141 spsA M Spore Coat
HOIIOEIH_00770 5.5e-71 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HOIIOEIH_00771 5.7e-59 ywdK S small membrane protein
HOIIOEIH_00772 1.7e-227 ywdJ F Xanthine uracil
HOIIOEIH_00773 4.2e-47 ywdI S Family of unknown function (DUF5327)
HOIIOEIH_00774 1.2e-250 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HOIIOEIH_00775 6.8e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HOIIOEIH_00776 5.7e-149 ywdF GT2,GT4 S Glycosyltransferase like family 2
HOIIOEIH_00778 2.2e-95 ywdD
HOIIOEIH_00779 2.6e-55 pex K Transcriptional regulator PadR-like family
HOIIOEIH_00780 1.5e-144 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HOIIOEIH_00781 4.1e-29 ywdA
HOIIOEIH_00782 1.2e-279 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HOIIOEIH_00783 3.8e-249 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOIIOEIH_00784 5.5e-133 focA P Formate/nitrite transporter
HOIIOEIH_00785 1.5e-147 sacT K transcriptional antiterminator
HOIIOEIH_00787 0.0 vpr O Belongs to the peptidase S8 family
HOIIOEIH_00788 5.1e-179 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOIIOEIH_00789 7e-133 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HOIIOEIH_00790 4e-199 rodA D Belongs to the SEDS family
HOIIOEIH_00791 4e-204 S Acetyltransferase
HOIIOEIH_00792 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HOIIOEIH_00793 2e-64 qoxD 1.10.3.12 C quinol oxidase, subunit
HOIIOEIH_00794 2.8e-111 qoxC 1.10.3.12 C quinol oxidase, subunit
HOIIOEIH_00795 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HOIIOEIH_00796 3.6e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HOIIOEIH_00797 9.7e-31 ywzA S membrane
HOIIOEIH_00798 6.6e-295 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HOIIOEIH_00799 3.4e-219 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HOIIOEIH_00800 1.1e-58 gtcA S GtrA-like protein
HOIIOEIH_00801 7.2e-113 ywcC K transcriptional regulator
HOIIOEIH_00803 1.7e-48 ywcB S Protein of unknown function, DUF485
HOIIOEIH_00804 2.4e-265 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOIIOEIH_00805 1.5e-109 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HOIIOEIH_00806 7.9e-222 ywbN P Dyp-type peroxidase family protein
HOIIOEIH_00807 2.5e-161 ycdO P periplasmic lipoprotein involved in iron transport
HOIIOEIH_00808 1.5e-245 P COG0672 High-affinity Fe2 Pb2 permease
HOIIOEIH_00809 8.2e-109 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HOIIOEIH_00810 1.9e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HOIIOEIH_00811 1.3e-149 ywbI K Transcriptional regulator
HOIIOEIH_00812 5.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HOIIOEIH_00813 6.8e-111 ywbG M effector of murein hydrolase
HOIIOEIH_00814 4.8e-208 ywbF EGP Major facilitator Superfamily
HOIIOEIH_00815 3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HOIIOEIH_00816 2.2e-213 ywbD 2.1.1.191 J Methyltransferase
HOIIOEIH_00817 2.2e-66 ywbC 4.4.1.5 E glyoxalase
HOIIOEIH_00818 1.6e-104 ywbB S Protein of unknown function (DUF2711)
HOIIOEIH_00819 1.2e-236 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIIOEIH_00820 7.1e-262 epr 3.4.21.62 O Belongs to the peptidase S8 family
HOIIOEIH_00821 1.9e-232 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOIIOEIH_00822 1.9e-150 sacY K transcriptional antiterminator
HOIIOEIH_00823 4.7e-165 gspA M General stress
HOIIOEIH_00824 6.7e-117 ywaF S Integral membrane protein
HOIIOEIH_00825 2.1e-83 ywaE K Transcriptional regulator
HOIIOEIH_00826 7.5e-225 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOIIOEIH_00827 1.3e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HOIIOEIH_00828 4.3e-115 ywaC 2.7.6.5 S protein conserved in bacteria
HOIIOEIH_00829 6.1e-143 L Molecular Function DNA binding, Biological Process DNA recombination
HOIIOEIH_00830 1.9e-42 L COG2963 Transposase and inactivated derivatives
HOIIOEIH_00831 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HOIIOEIH_00832 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
HOIIOEIH_00833 7.4e-283 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOIIOEIH_00834 2e-230 dltB M membrane protein involved in D-alanine export
HOIIOEIH_00835 5.6e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOIIOEIH_00836 6.9e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HOIIOEIH_00837 2e-135 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_00838 5.9e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HOIIOEIH_00839 4.3e-250 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HOIIOEIH_00840 1.5e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HOIIOEIH_00841 9.1e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIIOEIH_00842 8.9e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HOIIOEIH_00843 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HOIIOEIH_00844 1.2e-106 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HOIIOEIH_00845 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HOIIOEIH_00846 1.6e-203 yxlH EGP Major facilitator Superfamily
HOIIOEIH_00847 1.4e-131 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HOIIOEIH_00848 3.1e-156 yxlF V ABC transporter, ATP-binding protein
HOIIOEIH_00849 2.9e-27 yxlE S Phospholipase_D-nuclease N-terminal
HOIIOEIH_00850 6.4e-28
HOIIOEIH_00851 2.4e-37 yxlC S Family of unknown function (DUF5345)
HOIIOEIH_00852 7.8e-86 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HOIIOEIH_00853 1.7e-249 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HOIIOEIH_00854 6.7e-153 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOIIOEIH_00855 2.4e-311 cydD V ATP-binding protein
HOIIOEIH_00856 3e-304 cydD V ATP-binding
HOIIOEIH_00857 2.7e-188 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HOIIOEIH_00858 7.7e-266 cydA 1.10.3.14 C oxidase, subunit
HOIIOEIH_00859 4.4e-226 cimH C COG3493 Na citrate symporter
HOIIOEIH_00860 5.5e-287 3.4.24.84 O Peptidase family M48
HOIIOEIH_00862 7.8e-149 yxkH G Polysaccharide deacetylase
HOIIOEIH_00864 3.7e-94 P transporter
HOIIOEIH_00865 9.4e-203 msmK P Belongs to the ABC transporter superfamily
HOIIOEIH_00866 9.8e-150 lrp QT PucR C-terminal helix-turn-helix domain
HOIIOEIH_00867 9.1e-262 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HOIIOEIH_00868 1.6e-146 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOIIOEIH_00869 3.9e-133
HOIIOEIH_00870 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HOIIOEIH_00871 1.4e-73 S Protein of unknown function (DUF1453)
HOIIOEIH_00872 2.5e-164 yxjM T Signal transduction histidine kinase
HOIIOEIH_00873 1.2e-109 K helix_turn_helix, Lux Regulon
HOIIOEIH_00874 3.8e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HOIIOEIH_00875 6.7e-68 yxjI S LURP-one-related
HOIIOEIH_00876 6.5e-215 yxjG 2.1.1.14 E Methionine synthase
HOIIOEIH_00877 3.1e-217 yxjG 2.1.1.14 E Methionine synthase
HOIIOEIH_00878 2.1e-132 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HOIIOEIH_00879 3.5e-112 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HOIIOEIH_00880 3.8e-128 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HOIIOEIH_00881 4.6e-242 yxjC EG COG2610 H gluconate symporter and related permeases
HOIIOEIH_00882 2.2e-138 rlmA 2.1.1.187 Q Methyltransferase domain
HOIIOEIH_00883 9.2e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HOIIOEIH_00884 1.4e-108 T Domain of unknown function (DUF4163)
HOIIOEIH_00885 9e-44 yxiS
HOIIOEIH_00886 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HOIIOEIH_00887 8.9e-221 citH C Citrate transporter
HOIIOEIH_00888 1.6e-60 ydfR S Protein of unknown function (DUF421)
HOIIOEIH_00889 1.5e-163
HOIIOEIH_00890 1.6e-258 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HOIIOEIH_00891 1.6e-239 bglF G phosphotransferase system
HOIIOEIH_00892 1.2e-146 licT K transcriptional antiterminator
HOIIOEIH_00893 4.8e-80
HOIIOEIH_00894 1.2e-222 yxiO S COG2270 Permeases of the major facilitator superfamily
HOIIOEIH_00895 9.9e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HOIIOEIH_00896 1.3e-210 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HOIIOEIH_00899 1.1e-41 yxiJ S YxiJ-like protein
HOIIOEIH_00901 1.3e-35 yxiI S Protein of unknown function (DUF2716)
HOIIOEIH_00902 1.7e-18 yxiG
HOIIOEIH_00903 5.8e-56
HOIIOEIH_00904 3.4e-11
HOIIOEIH_00905 1.6e-94 S Protein of unknown function (DUF4240)
HOIIOEIH_00906 1.7e-140
HOIIOEIH_00907 1.5e-49 yxiG
HOIIOEIH_00909 0.0 wapA M COG3209 Rhs family protein
HOIIOEIH_00910 2.1e-158 yxxF EG EamA-like transporter family
HOIIOEIH_00911 1.2e-68 yxiE T Belongs to the universal stress protein A family
HOIIOEIH_00912 6.9e-275 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HOIIOEIH_00913 5.6e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOIIOEIH_00914 2.5e-14 S Uncharacterized protein conserved in bacteria (DUF2247)
HOIIOEIH_00915 3.5e-26
HOIIOEIH_00916 1e-62 L Belongs to the WXG100 family
HOIIOEIH_00917 2e-269 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HOIIOEIH_00918 1.5e-122 S Oxidoreductase NAD-binding domain protein
HOIIOEIH_00919 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HOIIOEIH_00920 2.5e-278 hutH 4.3.1.3 E Histidine ammonia-lyase
HOIIOEIH_00921 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HOIIOEIH_00922 4.2e-231 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HOIIOEIH_00923 9.2e-170 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HOIIOEIH_00924 1.4e-254 lysP E amino acid
HOIIOEIH_00925 2.4e-229 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HOIIOEIH_00926 3.1e-204 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HOIIOEIH_00927 4.2e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HOIIOEIH_00928 4e-170 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HOIIOEIH_00929 9.7e-144 yxxB S Domain of Unknown Function (DUF1206)
HOIIOEIH_00930 2.3e-188 eutH E Ethanolamine utilisation protein, EutH
HOIIOEIH_00931 1.1e-232 yxeQ S MmgE/PrpD family
HOIIOEIH_00932 4.1e-209 yxeP 3.5.1.47 E hydrolase activity
HOIIOEIH_00933 1e-128 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HOIIOEIH_00934 7.7e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
HOIIOEIH_00935 2.5e-141 yxeM M Belongs to the bacterial solute-binding protein 3 family
HOIIOEIH_00936 1.2e-88 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOIIOEIH_00937 2.9e-251 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOIIOEIH_00938 2.7e-172 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HOIIOEIH_00939 4.6e-146 yidA S hydrolases of the HAD superfamily
HOIIOEIH_00942 1.3e-07 yxeE
HOIIOEIH_00943 6.2e-15 yxeD
HOIIOEIH_00944 8.5e-69
HOIIOEIH_00945 5.2e-173 fhuD P ABC transporter
HOIIOEIH_00946 7.6e-58 yxeA S Protein of unknown function (DUF1093)
HOIIOEIH_00947 0.0 yxdM V ABC transporter (permease)
HOIIOEIH_00948 2.6e-138 yxdL V ABC transporter, ATP-binding protein
HOIIOEIH_00949 1.1e-178 T PhoQ Sensor
HOIIOEIH_00950 3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_00951 3.5e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HOIIOEIH_00952 7e-150 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HOIIOEIH_00953 1.9e-166 iolH G Xylose isomerase-like TIM barrel
HOIIOEIH_00954 3.4e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HOIIOEIH_00955 4.9e-230 iolF EGP Major facilitator Superfamily
HOIIOEIH_00956 3.8e-170 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HOIIOEIH_00957 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HOIIOEIH_00958 1.8e-176 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HOIIOEIH_00959 1.6e-151 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HOIIOEIH_00960 2.6e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HOIIOEIH_00961 9.5e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HOIIOEIH_00962 2.7e-174 iolS C Aldo keto reductase
HOIIOEIH_00964 1.1e-49 yxcD S Protein of unknown function (DUF2653)
HOIIOEIH_00965 5.6e-229 csbC EGP Major facilitator Superfamily
HOIIOEIH_00966 0.0 htpG O Molecular chaperone. Has ATPase activity
HOIIOEIH_00968 1.4e-147 IQ Enoyl-(Acyl carrier protein) reductase
HOIIOEIH_00970 4.4e-195 yxbF K Bacterial regulatory proteins, tetR family
HOIIOEIH_00971 1.1e-242 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HOIIOEIH_00972 1.3e-25 yxaI S membrane protein domain
HOIIOEIH_00973 3.4e-52 S Family of unknown function (DUF5391)
HOIIOEIH_00974 2.1e-71 yxaI S membrane protein domain
HOIIOEIH_00975 5e-213 P Protein of unknown function (DUF418)
HOIIOEIH_00976 2.6e-183 yxaG 1.13.11.24 S AraC-like ligand binding domain
HOIIOEIH_00977 1.9e-98 yxaF K Transcriptional regulator
HOIIOEIH_00978 1.2e-186 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_00979 3.1e-69 yxaD K helix_turn_helix multiple antibiotic resistance protein
HOIIOEIH_00980 3.4e-41 S LrgA family
HOIIOEIH_00981 1.6e-115 yxaC M effector of murein hydrolase
HOIIOEIH_00982 1.5e-209 nhaS2 P Sodium/hydrogen exchanger family
HOIIOEIH_00983 8e-188 yxaB GM Polysaccharide pyruvyl transferase
HOIIOEIH_00984 9.5e-190 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HOIIOEIH_00985 5.8e-124 gntR K transcriptional
HOIIOEIH_00986 2.3e-292 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HOIIOEIH_00987 1.4e-227 gntP EG COG2610 H gluconate symporter and related permeases
HOIIOEIH_00988 2.2e-268 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOIIOEIH_00989 4.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HOIIOEIH_00990 2.3e-284 ahpF O Alkyl hydroperoxide reductase
HOIIOEIH_00991 5.4e-199 XK27_00240 S Fic/DOC family
HOIIOEIH_00992 4.7e-188 wgaE S Polysaccharide pyruvyl transferase
HOIIOEIH_00993 3.3e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HOIIOEIH_00994 0.0 bglF G phosphotransferase system
HOIIOEIH_00995 5.1e-125 yydK K Transcriptional regulator
HOIIOEIH_00996 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HOIIOEIH_00997 2e-61 2.7.7.49 L DNA polymerase
HOIIOEIH_00998 6e-110 L AAA ATPase domain
HOIIOEIH_00999 2.5e-100 2.7.11.1 KLT Protein kinase domain
HOIIOEIH_01000 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOIIOEIH_01001 1.1e-09 S YyzF-like protein
HOIIOEIH_01002 1.8e-61
HOIIOEIH_01003 2.1e-232 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HOIIOEIH_01005 8.4e-27 yycQ S Protein of unknown function (DUF2651)
HOIIOEIH_01006 4.6e-192 yycP
HOIIOEIH_01007 9.6e-127 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HOIIOEIH_01008 1.9e-80 yycN 2.3.1.128 K Acetyltransferase
HOIIOEIH_01009 8.5e-188 S aspartate phosphatase
HOIIOEIH_01011 2.8e-165 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HOIIOEIH_01012 5.2e-257 rocE E amino acid
HOIIOEIH_01013 5.3e-231 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HOIIOEIH_01014 7.3e-253 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HOIIOEIH_01015 1.9e-39 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HOIIOEIH_01016 2.2e-213 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HOIIOEIH_01017 4.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HOIIOEIH_01018 1.7e-148 yycI S protein conserved in bacteria
HOIIOEIH_01019 1.3e-249 yycH S protein conserved in bacteria
HOIIOEIH_01020 0.0 vicK 2.7.13.3 T Histidine kinase
HOIIOEIH_01021 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_01026 1.5e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOIIOEIH_01027 3.4e-68 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOIIOEIH_01028 1.5e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HOIIOEIH_01029 9.1e-27 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HOIIOEIH_01031 1.9e-15 yycC K YycC-like protein
HOIIOEIH_01032 7.2e-204 yeaN P COG2807 Cyanate permease
HOIIOEIH_01033 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOIIOEIH_01034 5.4e-72 rplI J binds to the 23S rRNA
HOIIOEIH_01035 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HOIIOEIH_01036 3.7e-152 yybS S membrane
HOIIOEIH_01038 4.7e-82 cotF M Spore coat protein
HOIIOEIH_01039 1.5e-67 ydeP3 K Transcriptional regulator
HOIIOEIH_01040 7.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HOIIOEIH_01041 1.5e-66
HOIIOEIH_01043 1.1e-237 yybO G COG0477 Permeases of the major facilitator superfamily
HOIIOEIH_01044 9.3e-120
HOIIOEIH_01045 1.4e-51 yybH S SnoaL-like domain
HOIIOEIH_01046 2.4e-118 yybG S Pentapeptide repeat-containing protein
HOIIOEIH_01047 7.4e-201 ynfM EGP Major facilitator Superfamily
HOIIOEIH_01048 3.9e-159 yybE K Transcriptional regulator
HOIIOEIH_01049 3.6e-68 yjcF S Acetyltransferase (GNAT) domain
HOIIOEIH_01050 2.9e-71 yybC
HOIIOEIH_01051 6.6e-119 S Metallo-beta-lactamase superfamily
HOIIOEIH_01052 1.9e-40 yybR K Transcriptional regulator
HOIIOEIH_01053 2.9e-73 yybA 2.3.1.57 K transcriptional
HOIIOEIH_01054 3.8e-67 yjcF S Acetyltransferase (GNAT) domain
HOIIOEIH_01055 8.6e-89 yyaS S Membrane
HOIIOEIH_01056 2.7e-66 S Putative inner membrane exporter, YdcZ
HOIIOEIH_01057 2.8e-62 S Putative inner membrane exporter, YdcZ
HOIIOEIH_01058 1.1e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HOIIOEIH_01059 4e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HOIIOEIH_01060 1.8e-76 T Nacht domain
HOIIOEIH_01061 1.2e-54 L Recombinase
HOIIOEIH_01062 4.6e-61
HOIIOEIH_01064 2e-09 S Domain of unknown function with cystatin-like fold (DUF4467)
HOIIOEIH_01065 3.8e-24 S Domain of unknown function with cystatin-like fold (DUF4467)
HOIIOEIH_01066 1.3e-23 S response regulator aspartate phosphatase
HOIIOEIH_01068 5.4e-74 betI9 K Bacterial regulatory proteins, tetR family
HOIIOEIH_01069 1.6e-50 qacC U Quaternary ammonium transporter
HOIIOEIH_01070 5.7e-24 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HOIIOEIH_01071 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HOIIOEIH_01072 7.3e-161 yyaK S CAAX protease self-immunity
HOIIOEIH_01073 6.1e-236 EGP Major facilitator superfamily
HOIIOEIH_01074 1.9e-90 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HOIIOEIH_01075 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOIIOEIH_01076 1.6e-163 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HOIIOEIH_01077 1.7e-139 xth 3.1.11.2 L exodeoxyribonuclease III
HOIIOEIH_01078 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HOIIOEIH_01079 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HOIIOEIH_01080 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
HOIIOEIH_01081 4.8e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HOIIOEIH_01082 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HOIIOEIH_01083 6.6e-33 yyzM S protein conserved in bacteria
HOIIOEIH_01084 4.8e-177 yyaD S Membrane
HOIIOEIH_01085 3.8e-108 yyaC S Sporulation protein YyaC
HOIIOEIH_01086 7.4e-147 spo0J K Belongs to the ParB family
HOIIOEIH_01087 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HOIIOEIH_01088 2.3e-67 S Bacterial PH domain
HOIIOEIH_01089 1.4e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HOIIOEIH_01090 4.5e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HOIIOEIH_01091 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HOIIOEIH_01092 4.1e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HOIIOEIH_01093 4.8e-103 jag S single-stranded nucleic acid binding R3H
HOIIOEIH_01094 1.1e-117 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOIIOEIH_01095 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HOIIOEIH_01096 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HOIIOEIH_01097 3e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HOIIOEIH_01098 2.4e-33 yaaA S S4 domain
HOIIOEIH_01099 3.5e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOIIOEIH_01100 1.8e-37 yaaB S Domain of unknown function (DUF370)
HOIIOEIH_01101 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOIIOEIH_01102 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOIIOEIH_01103 3.4e-39 S COG NOG14552 non supervised orthologous group
HOIIOEIH_01106 4.7e-169 yaaC S YaaC-like Protein
HOIIOEIH_01107 1.7e-271 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HOIIOEIH_01108 6e-244 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HOIIOEIH_01109 4.8e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HOIIOEIH_01110 1.7e-105 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HOIIOEIH_01111 6.9e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOIIOEIH_01112 1.3e-09
HOIIOEIH_01113 2e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HOIIOEIH_01114 3.1e-110 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HOIIOEIH_01115 5.1e-208 yaaH M Glycoside Hydrolase Family
HOIIOEIH_01116 6.3e-91 yaaI Q COG1335 Amidases related to nicotinamidase
HOIIOEIH_01117 1.3e-82 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HOIIOEIH_01118 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOIIOEIH_01119 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HOIIOEIH_01120 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOIIOEIH_01121 2.3e-31 yaaL S Protein of unknown function (DUF2508)
HOIIOEIH_01122 1.8e-35 bofA S Sigma-K factor-processing regulatory protein BofA
HOIIOEIH_01123 3.4e-39 S COG NOG14552 non supervised orthologous group
HOIIOEIH_01126 4.9e-30 csfB S Inhibitor of sigma-G Gin
HOIIOEIH_01127 5.6e-96 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HOIIOEIH_01128 1.8e-191 yaaN P Belongs to the TelA family
HOIIOEIH_01129 7.1e-259 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HOIIOEIH_01130 1.3e-106 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HOIIOEIH_01131 8.3e-54 yaaQ S protein conserved in bacteria
HOIIOEIH_01132 1.7e-70 yaaR S protein conserved in bacteria
HOIIOEIH_01133 2.1e-177 holB 2.7.7.7 L DNA polymerase III
HOIIOEIH_01134 8.8e-145 yaaT S stage 0 sporulation protein
HOIIOEIH_01135 4.8e-31 yabA L Involved in initiation control of chromosome replication
HOIIOEIH_01136 3e-136 yabB 2.1.1.223 S Conserved hypothetical protein 95
HOIIOEIH_01137 4e-47 yazA L endonuclease containing a URI domain
HOIIOEIH_01138 3.9e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOIIOEIH_01139 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HOIIOEIH_01140 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOIIOEIH_01141 3.8e-142 tatD L hydrolase, TatD
HOIIOEIH_01142 6.2e-163 rpfB GH23 T protein conserved in bacteria
HOIIOEIH_01143 1.1e-93 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HOIIOEIH_01144 6.5e-154 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HOIIOEIH_01145 1.5e-134 yabG S peptidase
HOIIOEIH_01146 7.8e-39 veg S protein conserved in bacteria
HOIIOEIH_01147 8.3e-27 sspF S DNA topological change
HOIIOEIH_01148 1.5e-158 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HOIIOEIH_01149 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HOIIOEIH_01150 1.9e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HOIIOEIH_01151 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HOIIOEIH_01152 2.6e-226 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOIIOEIH_01153 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOIIOEIH_01154 1.8e-94 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HOIIOEIH_01155 1.2e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HOIIOEIH_01156 4.9e-37 yabK S Peptide ABC transporter permease
HOIIOEIH_01157 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOIIOEIH_01158 1.5e-92 spoVT K stage V sporulation protein
HOIIOEIH_01159 1.1e-271 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOIIOEIH_01160 2.7e-237 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HOIIOEIH_01161 2.5e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HOIIOEIH_01162 1.4e-47 yabP S Sporulation protein YabP
HOIIOEIH_01163 2.1e-101 yabQ S spore cortex biosynthesis protein
HOIIOEIH_01164 1.4e-44 divIC D Septum formation initiator
HOIIOEIH_01165 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HOIIOEIH_01168 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HOIIOEIH_01169 1.9e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
HOIIOEIH_01170 3.6e-180 KLT serine threonine protein kinase
HOIIOEIH_01171 2.4e-267 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HOIIOEIH_01172 2.3e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HOIIOEIH_01173 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOIIOEIH_01174 1.3e-145 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HOIIOEIH_01175 4.2e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HOIIOEIH_01176 7.9e-149 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HOIIOEIH_01177 9.8e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HOIIOEIH_01178 7.4e-261 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOIIOEIH_01179 4e-104 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HOIIOEIH_01180 6.9e-156 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HOIIOEIH_01181 5.2e-156 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HOIIOEIH_01182 8.5e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HOIIOEIH_01183 1.6e-85 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HOIIOEIH_01184 1.6e-29 yazB K transcriptional
HOIIOEIH_01185 1.7e-187 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOIIOEIH_01186 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HOIIOEIH_01187 3.4e-39 S COG NOG14552 non supervised orthologous group
HOIIOEIH_01192 2e-08
HOIIOEIH_01197 3.4e-39 S COG NOG14552 non supervised orthologous group
HOIIOEIH_01198 2.9e-15
HOIIOEIH_01199 2.9e-76 ctsR K Belongs to the CtsR family
HOIIOEIH_01200 1.1e-56 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HOIIOEIH_01201 3.9e-201 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HOIIOEIH_01202 0.0 clpC O Belongs to the ClpA ClpB family
HOIIOEIH_01203 5.8e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOIIOEIH_01204 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HOIIOEIH_01205 1.3e-196 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HOIIOEIH_01206 2.8e-120 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HOIIOEIH_01207 9.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HOIIOEIH_01208 4e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOIIOEIH_01209 2.1e-117 cysE 2.3.1.30 E Serine acetyltransferase
HOIIOEIH_01210 1.6e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOIIOEIH_01211 2.6e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HOIIOEIH_01212 9.8e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOIIOEIH_01213 4.7e-88 yacP S RNA-binding protein containing a PIN domain
HOIIOEIH_01214 4.4e-115 sigH K Belongs to the sigma-70 factor family
HOIIOEIH_01215 3.9e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HOIIOEIH_01216 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
HOIIOEIH_01217 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HOIIOEIH_01218 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HOIIOEIH_01219 2.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOIIOEIH_01220 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HOIIOEIH_01221 9.1e-107 rsmC 2.1.1.172 J Methyltransferase
HOIIOEIH_01222 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOIIOEIH_01223 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOIIOEIH_01224 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HOIIOEIH_01225 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HOIIOEIH_01226 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HOIIOEIH_01227 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOIIOEIH_01228 1e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOIIOEIH_01229 1.1e-159 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HOIIOEIH_01230 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HOIIOEIH_01231 7e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOIIOEIH_01232 1.1e-104 rplD J Forms part of the polypeptide exit tunnel
HOIIOEIH_01233 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HOIIOEIH_01234 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOIIOEIH_01235 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOIIOEIH_01236 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOIIOEIH_01237 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOIIOEIH_01238 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HOIIOEIH_01239 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HOIIOEIH_01240 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOIIOEIH_01241 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HOIIOEIH_01242 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HOIIOEIH_01243 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOIIOEIH_01244 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOIIOEIH_01245 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HOIIOEIH_01246 1.9e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOIIOEIH_01247 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HOIIOEIH_01248 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HOIIOEIH_01249 1.9e-23 rpmD J Ribosomal protein L30
HOIIOEIH_01250 1.8e-72 rplO J binds to the 23S rRNA
HOIIOEIH_01251 5.1e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HOIIOEIH_01252 9.8e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HOIIOEIH_01253 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HOIIOEIH_01254 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOIIOEIH_01255 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HOIIOEIH_01256 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOIIOEIH_01257 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOIIOEIH_01258 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOIIOEIH_01259 3.6e-58 rplQ J Ribosomal protein L17
HOIIOEIH_01260 9.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOIIOEIH_01261 5.2e-156 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOIIOEIH_01262 6.5e-121 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOIIOEIH_01263 6.5e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HOIIOEIH_01264 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HOIIOEIH_01265 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HOIIOEIH_01266 1.7e-134 ybaJ Q Methyltransferase domain
HOIIOEIH_01267 2e-63 ybaK S Protein of unknown function (DUF2521)
HOIIOEIH_01268 2.6e-129 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HOIIOEIH_01269 4.8e-196 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HOIIOEIH_01270 1.1e-82 gerD
HOIIOEIH_01271 4.3e-101 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HOIIOEIH_01272 2.9e-134 pdaB 3.5.1.104 G Polysaccharide deacetylase
HOIIOEIH_01273 3.4e-39 S COG NOG14552 non supervised orthologous group
HOIIOEIH_01276 2e-08
HOIIOEIH_01280 3.4e-39 S COG NOG14552 non supervised orthologous group
HOIIOEIH_01281 3.4e-39 S COG NOG14552 non supervised orthologous group
HOIIOEIH_01282 3.6e-171 glcP G Major Facilitator Superfamily
HOIIOEIH_01283 2.9e-232 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOIIOEIH_01284 6.8e-157 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HOIIOEIH_01285 3e-174 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HOIIOEIH_01286 2.5e-248 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HOIIOEIH_01287 2e-161 ybaS 1.1.1.58 S Na -dependent transporter
HOIIOEIH_01288 8.5e-123 ybbA S Putative esterase
HOIIOEIH_01289 1.1e-176 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_01290 3.8e-174 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_01291 1.2e-161 feuA P Iron-uptake system-binding protein
HOIIOEIH_01292 6.6e-282 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HOIIOEIH_01293 7.8e-230 ybbC 3.2.1.52 S protein conserved in bacteria
HOIIOEIH_01294 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HOIIOEIH_01295 4.3e-242 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HOIIOEIH_01296 4e-227 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOIIOEIH_01297 6.1e-141 ybbH K transcriptional
HOIIOEIH_01298 2.8e-152 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HOIIOEIH_01299 8.9e-81 ybbJ J acetyltransferase
HOIIOEIH_01300 2.2e-73 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HOIIOEIH_01306 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HOIIOEIH_01307 3.2e-99 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HOIIOEIH_01308 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HOIIOEIH_01309 1.3e-220 ybbR S protein conserved in bacteria
HOIIOEIH_01310 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOIIOEIH_01311 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HOIIOEIH_01312 9.2e-257 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HOIIOEIH_01313 0.0 ybcC S Belongs to the UPF0753 family
HOIIOEIH_01314 1.1e-79 can 4.2.1.1 P carbonic anhydrase
HOIIOEIH_01315 1.4e-41
HOIIOEIH_01316 4.4e-59 ybcI S Uncharacterized conserved protein (DUF2294)
HOIIOEIH_01317 2.5e-49 ybzH K Helix-turn-helix domain
HOIIOEIH_01318 6.7e-199 ybcL EGP Major facilitator Superfamily
HOIIOEIH_01319 1.5e-50
HOIIOEIH_01320 1.1e-173 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HOIIOEIH_01321 2.2e-117 T Transcriptional regulatory protein, C terminal
HOIIOEIH_01322 1.4e-157 T His Kinase A (phospho-acceptor) domain
HOIIOEIH_01324 4.8e-129 KLT Protein tyrosine kinase
HOIIOEIH_01325 2.2e-146 ybdN
HOIIOEIH_01326 1.1e-191 ybdO S Domain of unknown function (DUF4885)
HOIIOEIH_01327 1.6e-255 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HOIIOEIH_01328 4.2e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
HOIIOEIH_01329 5.4e-29 ybxH S Family of unknown function (DUF5370)
HOIIOEIH_01330 1.6e-143 ybxI 3.5.2.6 V beta-lactamase
HOIIOEIH_01331 1.9e-231 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HOIIOEIH_01332 7e-40 ybyB
HOIIOEIH_01333 1.5e-276 nptA P COG1283 Na phosphate symporter
HOIIOEIH_01334 8.5e-154 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HOIIOEIH_01335 4e-256 glpT G -transporter
HOIIOEIH_01336 5.5e-26 S Protein of unknown function (DUF2651)
HOIIOEIH_01337 4.8e-160 ybfA 3.4.15.5 K FR47-like protein
HOIIOEIH_01338 5.5e-215 ybfB G COG0477 Permeases of the major facilitator superfamily
HOIIOEIH_01341 8.3e-152 ybfH EG EamA-like transporter family
HOIIOEIH_01342 7.7e-141 msmR K AraC-like ligand binding domain
HOIIOEIH_01343 5.6e-206 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HOIIOEIH_01344 1.7e-168 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HOIIOEIH_01346 8.8e-151 S Alpha/beta hydrolase family
HOIIOEIH_01347 1.2e-91 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOIIOEIH_01348 1.3e-82 ybfM S SNARE associated Golgi protein
HOIIOEIH_01349 4.2e-144 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HOIIOEIH_01350 6.8e-41 ybfN
HOIIOEIH_01351 1.8e-240 S Erythromycin esterase
HOIIOEIH_01352 1.2e-188 yceA S Belongs to the UPF0176 family
HOIIOEIH_01353 2.4e-210 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOIIOEIH_01354 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOIIOEIH_01355 1.2e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HOIIOEIH_01356 6.4e-128 K UTRA
HOIIOEIH_01358 1.3e-193 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HOIIOEIH_01359 1.5e-253 mmuP E amino acid
HOIIOEIH_01360 8.7e-173 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HOIIOEIH_01361 5.1e-249 agcS E Sodium alanine symporter
HOIIOEIH_01362 1.1e-181 glsA 3.5.1.2 E Belongs to the glutaminase family
HOIIOEIH_01363 2.8e-222 phoQ 2.7.13.3 T Histidine kinase
HOIIOEIH_01364 5.9e-161 glnL T Regulator
HOIIOEIH_01365 2.6e-169 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HOIIOEIH_01366 5.5e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HOIIOEIH_01367 3.4e-250 gudP G COG0477 Permeases of the major facilitator superfamily
HOIIOEIH_01368 1.7e-262 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HOIIOEIH_01369 4e-122 ycbG K FCD
HOIIOEIH_01370 3.7e-290 garD 4.2.1.42, 4.2.1.7 G Altronate
HOIIOEIH_01371 1.4e-154 ycbJ S Macrolide 2'-phosphotransferase
HOIIOEIH_01372 3.8e-20 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HOIIOEIH_01373 4.6e-150 eamA1 EG spore germination
HOIIOEIH_01374 7.4e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_01375 3.3e-156 T PhoQ Sensor
HOIIOEIH_01376 1.5e-161 ycbN V ABC transporter, ATP-binding protein
HOIIOEIH_01377 2.5e-108 S ABC-2 family transporter protein
HOIIOEIH_01378 1.4e-52 ycbP S Protein of unknown function (DUF2512)
HOIIOEIH_01379 6e-97 O Belongs to the serpin family
HOIIOEIH_01380 4.1e-77 sleB 3.5.1.28 M Cell wall
HOIIOEIH_01381 7.9e-129 ycbR T vWA found in TerF C terminus
HOIIOEIH_01382 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HOIIOEIH_01383 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HOIIOEIH_01384 4.6e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HOIIOEIH_01385 1.1e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HOIIOEIH_01386 8.1e-186 ycbU E Selenocysteine lyase
HOIIOEIH_01387 1.4e-230 lmrB EGP the major facilitator superfamily
HOIIOEIH_01388 1.5e-98 yxaF K Transcriptional regulator
HOIIOEIH_01389 2.5e-182 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HOIIOEIH_01390 3.8e-103 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HOIIOEIH_01391 5.2e-55 S RDD family
HOIIOEIH_01392 4.6e-194 yccF K DNA-templated transcriptional preinitiation complex assembly
HOIIOEIH_01393 4.7e-134 2.7.13.3 T GHKL domain
HOIIOEIH_01394 3.1e-122 lytR_2 T LytTr DNA-binding domain
HOIIOEIH_01395 6.1e-129 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HOIIOEIH_01396 4.5e-195 natB CP ABC-2 family transporter protein
HOIIOEIH_01397 2.2e-168 yccK C Aldo keto reductase
HOIIOEIH_01398 4.7e-175 ycdA S Domain of unknown function (DUF5105)
HOIIOEIH_01399 1.1e-240 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HOIIOEIH_01400 8.5e-246 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HOIIOEIH_01401 1.3e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
HOIIOEIH_01402 7.2e-174 S response regulator aspartate phosphatase
HOIIOEIH_01403 4.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
HOIIOEIH_01404 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HOIIOEIH_01405 1.7e-158 adcA P Belongs to the bacterial solute-binding protein 9 family
HOIIOEIH_01406 1e-130 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HOIIOEIH_01407 5.1e-132 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HOIIOEIH_01408 4.7e-177 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HOIIOEIH_01409 3.1e-107 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HOIIOEIH_01410 4.1e-104 yceD T proteins involved in stress response, homologs of TerZ and
HOIIOEIH_01411 1.8e-107 yceE T proteins involved in stress response, homologs of TerZ and
HOIIOEIH_01412 5e-134 terC P Protein of unknown function (DUF475)
HOIIOEIH_01413 6.7e-311 yceG S Putative component of 'biosynthetic module'
HOIIOEIH_01414 1.8e-190 yceH P Belongs to the TelA family
HOIIOEIH_01415 1.8e-215 naiP P Uncharacterised MFS-type transporter YbfB
HOIIOEIH_01416 2.2e-31 K helix_turn_helix, Arsenical Resistance Operon Repressor
HOIIOEIH_01417 9.4e-223 proV 3.6.3.32 E glycine betaine
HOIIOEIH_01418 1e-127 opuAB P glycine betaine
HOIIOEIH_01419 6.7e-159 opuAC E glycine betaine
HOIIOEIH_01420 3.3e-214 amhX S amidohydrolase
HOIIOEIH_01421 1.2e-255 ycgA S Membrane
HOIIOEIH_01422 6.1e-77 ycgB
HOIIOEIH_01423 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HOIIOEIH_01424 6.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HOIIOEIH_01425 1.4e-282 lctP C L-lactate permease
HOIIOEIH_01426 2.8e-261 mdr EGP Major facilitator Superfamily
HOIIOEIH_01427 4.1e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
HOIIOEIH_01428 1.4e-110 ycgF E Lysine exporter protein LysE YggA
HOIIOEIH_01429 3.6e-145 yqcI S YqcI/YcgG family
HOIIOEIH_01430 2.1e-241 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HOIIOEIH_01431 7.1e-112 ycgI S Domain of unknown function (DUF1989)
HOIIOEIH_01432 1.8e-145 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HOIIOEIH_01433 2.2e-61 tmrB S AAA domain
HOIIOEIH_01434 4e-101 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HOIIOEIH_01435 7.4e-130 yafE Q ubiE/COQ5 methyltransferase family
HOIIOEIH_01436 6.4e-171 oxyR3 K LysR substrate binding domain
HOIIOEIH_01437 2e-177 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HOIIOEIH_01438 1.2e-140 ycgL S Predicted nucleotidyltransferase
HOIIOEIH_01439 3.4e-166 ycgM E Proline dehydrogenase
HOIIOEIH_01440 4.4e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HOIIOEIH_01441 5.2e-254 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOIIOEIH_01442 4.4e-225 ycgP QT COG2508 Regulator of polyketide synthase expression
HOIIOEIH_01443 2e-144 ycgQ S membrane
HOIIOEIH_01444 1.7e-141 ycgR S permeases
HOIIOEIH_01445 2.8e-154 I alpha/beta hydrolase fold
HOIIOEIH_01446 1.8e-184 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HOIIOEIH_01447 1.4e-262 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HOIIOEIH_01448 3.9e-56 nirD 1.7.1.15 P Nitrite reductase
HOIIOEIH_01449 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HOIIOEIH_01450 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HOIIOEIH_01451 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HOIIOEIH_01452 7.1e-220 nasA P COG2223 Nitrate nitrite transporter
HOIIOEIH_01453 1.9e-156 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HOIIOEIH_01454 1.6e-92 yciB M ErfK YbiS YcfS YnhG
HOIIOEIH_01455 2.2e-194 P FAD-NAD(P)-binding
HOIIOEIH_01456 3.6e-224 yciC S GTPases (G3E family)
HOIIOEIH_01457 1.3e-114 yecS P COG0765 ABC-type amino acid transport system, permease component
HOIIOEIH_01458 1.9e-129 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HOIIOEIH_01461 1.5e-21 yckC S membrane
HOIIOEIH_01462 2.4e-48 yckD S Protein of unknown function (DUF2680)
HOIIOEIH_01463 2.8e-46 K MarR family
HOIIOEIH_01464 4.2e-24
HOIIOEIH_01465 9.5e-119 S AAA domain
HOIIOEIH_01466 1.4e-161 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HOIIOEIH_01467 2.1e-67 nin S Competence protein J (ComJ)
HOIIOEIH_01468 1.8e-67 nucA M Deoxyribonuclease NucA/NucB
HOIIOEIH_01469 3.7e-161 tlpC 2.7.13.3 NT chemotaxis protein
HOIIOEIH_01470 1.5e-92 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HOIIOEIH_01471 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HOIIOEIH_01472 9.1e-62 hxlR K transcriptional
HOIIOEIH_01473 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOIIOEIH_01474 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOIIOEIH_01475 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HOIIOEIH_01476 4.7e-134 srfAD Q thioesterase
HOIIOEIH_01477 4.1e-215 EGP Major Facilitator Superfamily
HOIIOEIH_01478 4.1e-77 S YcxB-like protein
HOIIOEIH_01479 1.5e-148 ycxC EG EamA-like transporter family
HOIIOEIH_01480 6e-244 ycxD K GntR family transcriptional regulator
HOIIOEIH_01481 3.3e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HOIIOEIH_01482 7e-113 yczE S membrane
HOIIOEIH_01483 1.5e-34 S Histidine kinase
HOIIOEIH_01484 2.4e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HOIIOEIH_01485 1.1e-122 tcyB P COG0765 ABC-type amino acid transport system, permease component
HOIIOEIH_01486 5.4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HOIIOEIH_01487 4.6e-160 bsdA K LysR substrate binding domain
HOIIOEIH_01488 1.6e-106 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HOIIOEIH_01489 1.7e-281 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HOIIOEIH_01490 1.5e-38 bsdD 4.1.1.61 S response to toxic substance
HOIIOEIH_01491 9.2e-75 yclD
HOIIOEIH_01492 5.6e-147 yclE 3.4.11.5 S Alpha beta hydrolase
HOIIOEIH_01493 1.7e-260 dtpT E amino acid peptide transporter
HOIIOEIH_01494 1.4e-289 yclG M Pectate lyase superfamily protein
HOIIOEIH_01496 2.3e-266 gerKA EG Spore germination protein
HOIIOEIH_01497 1.2e-211 gerKC S spore germination
HOIIOEIH_01498 2.2e-186 gerKB F Spore germination protein
HOIIOEIH_01499 4.4e-118 yclH P ABC transporter
HOIIOEIH_01500 3.7e-194 yclI V ABC transporter (permease) YclI
HOIIOEIH_01501 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_01502 4.2e-256 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HOIIOEIH_01503 3.6e-72 S aspartate phosphatase
HOIIOEIH_01506 8.5e-246 lysC 2.7.2.4 E Belongs to the aspartokinase family
HOIIOEIH_01507 1.3e-160 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_01508 3.4e-161 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_01509 2.9e-134 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HOIIOEIH_01510 1.9e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HOIIOEIH_01511 8.9e-246 ycnB EGP Major facilitator Superfamily
HOIIOEIH_01512 9.6e-150 ycnC K Transcriptional regulator
HOIIOEIH_01513 3.5e-132 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HOIIOEIH_01514 6.1e-45 ycnE S Monooxygenase
HOIIOEIH_01515 1.8e-50 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HOIIOEIH_01516 4.6e-258 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOIIOEIH_01517 1.6e-241 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOIIOEIH_01518 3.2e-256 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HOIIOEIH_01519 4.9e-146 glcU U Glucose uptake
HOIIOEIH_01520 7.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOIIOEIH_01521 1.3e-95 ycnI S protein conserved in bacteria
HOIIOEIH_01522 2.1e-291 ycnJ P protein, homolog of Cu resistance protein CopC
HOIIOEIH_01523 8.9e-104 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HOIIOEIH_01524 8.3e-52
HOIIOEIH_01525 9e-238 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HOIIOEIH_01526 7.5e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HOIIOEIH_01527 4.6e-205 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HOIIOEIH_01528 5.7e-197 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HOIIOEIH_01529 2.3e-97 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HOIIOEIH_01530 1.9e-65 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HOIIOEIH_01532 5.7e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HOIIOEIH_01533 1.1e-136 ycsF S Belongs to the UPF0271 (lamB) family
HOIIOEIH_01534 7.2e-204 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HOIIOEIH_01535 4.6e-143 ycsI S Belongs to the D-glutamate cyclase family
HOIIOEIH_01536 1.6e-129 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HOIIOEIH_01537 3.6e-177 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HOIIOEIH_01538 9.5e-130 kipR K Transcriptional regulator
HOIIOEIH_01539 8.7e-116 ycsK E anatomical structure formation involved in morphogenesis
HOIIOEIH_01541 1.6e-48 yczJ S biosynthesis
HOIIOEIH_01542 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HOIIOEIH_01543 2.8e-168 ydhF S Oxidoreductase
HOIIOEIH_01544 0.0 mtlR K transcriptional regulator, MtlR
HOIIOEIH_01545 1.4e-281 ydaB IQ acyl-CoA ligase
HOIIOEIH_01546 2.2e-89 ydaC Q Methyltransferase domain
HOIIOEIH_01547 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOIIOEIH_01548 6.2e-93 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HOIIOEIH_01549 2.3e-93 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HOIIOEIH_01550 2e-76 ydaG 1.4.3.5 S general stress protein
HOIIOEIH_01551 8.6e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HOIIOEIH_01552 1.8e-39 ydzA EGP Major facilitator Superfamily
HOIIOEIH_01553 2.1e-73 lrpC K Transcriptional regulator
HOIIOEIH_01554 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOIIOEIH_01555 6.9e-198 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HOIIOEIH_01556 5.3e-145 ydaK T Diguanylate cyclase, GGDEF domain
HOIIOEIH_01557 1.2e-308 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HOIIOEIH_01558 7.2e-231 ydaM M Glycosyl transferase family group 2
HOIIOEIH_01559 0.0 ydaN S Bacterial cellulose synthase subunit
HOIIOEIH_01560 0.0 ydaO E amino acid
HOIIOEIH_01561 5.8e-66 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HOIIOEIH_01562 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HOIIOEIH_01564 5.2e-38
HOIIOEIH_01565 7.3e-223 mntH P H( )-stimulated, divalent metal cation uptake system
HOIIOEIH_01567 7.3e-69 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HOIIOEIH_01568 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HOIIOEIH_01570 2.6e-52 ydbB G Cupin domain
HOIIOEIH_01571 1.1e-51 ydbC S Domain of unknown function (DUF4937
HOIIOEIH_01572 2.1e-151 ydbD P Catalase
HOIIOEIH_01573 3.9e-190 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HOIIOEIH_01574 6.4e-293 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HOIIOEIH_01575 2.4e-116 dctR T COG4565 Response regulator of citrate malate metabolism
HOIIOEIH_01576 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOIIOEIH_01577 7.4e-173 ydbI S AI-2E family transporter
HOIIOEIH_01578 2.1e-203 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOIIOEIH_01579 1e-165 ydbJ V ABC transporter, ATP-binding protein
HOIIOEIH_01580 3.3e-122 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HOIIOEIH_01581 2.7e-52 ydbL
HOIIOEIH_01582 1.7e-210 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HOIIOEIH_01583 1.1e-18 S Fur-regulated basic protein B
HOIIOEIH_01584 2.2e-07 S Fur-regulated basic protein A
HOIIOEIH_01585 3.5e-144 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOIIOEIH_01586 8.6e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HOIIOEIH_01587 2.5e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HOIIOEIH_01588 4.1e-248 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HOIIOEIH_01589 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HOIIOEIH_01590 2e-80 ydbS S Bacterial PH domain
HOIIOEIH_01591 7.9e-245 ydbT S Membrane
HOIIOEIH_01592 8.4e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HOIIOEIH_01593 3.4e-56 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HOIIOEIH_01594 1.3e-182 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HOIIOEIH_01595 1.6e-213 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOIIOEIH_01596 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HOIIOEIH_01597 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HOIIOEIH_01598 5.3e-142 rsbR T Positive regulator of sigma-B
HOIIOEIH_01599 5.2e-57 rsbS T antagonist
HOIIOEIH_01600 6.5e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HOIIOEIH_01601 5.1e-187 rsbU 3.1.3.3 KT phosphatase
HOIIOEIH_01602 1.3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
HOIIOEIH_01603 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HOIIOEIH_01604 8.4e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOIIOEIH_01605 4e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HOIIOEIH_01606 0.0 yhgF K COG2183 Transcriptional accessory protein
HOIIOEIH_01607 1.5e-82 ydcK S Belongs to the SprT family
HOIIOEIH_01615 5.7e-33 K Helix-turn-helix XRE-family like proteins
HOIIOEIH_01616 1.6e-39
HOIIOEIH_01617 1.7e-124 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
HOIIOEIH_01618 3.5e-153 yeaN P transporter
HOIIOEIH_01619 3.4e-134 cynR K Transcriptional regulator
HOIIOEIH_01620 9.2e-86 S protein conserved in bacteria
HOIIOEIH_01621 9e-41 MA20_06410 E threonine efflux protein
HOIIOEIH_01622 1.4e-49 ypaA S Protein of unknown function (DUF1304)
HOIIOEIH_01623 1.9e-189 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HOIIOEIH_01624 5.2e-30 cspL K Cold shock
HOIIOEIH_01625 1.3e-73 carD K Transcription factor
HOIIOEIH_01626 1.1e-108 K FCD
HOIIOEIH_01627 6.3e-192 yeaN P COG2807 Cyanate permease
HOIIOEIH_01628 7.9e-87 K Helix-turn-helix XRE-family like proteins
HOIIOEIH_01629 6.6e-159 ydeE K AraC family transcriptional regulator
HOIIOEIH_01630 5.2e-44 ydeH
HOIIOEIH_01631 1.1e-93 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HOIIOEIH_01632 5.8e-85 S CAAX protease self-immunity
HOIIOEIH_01635 2.1e-70
HOIIOEIH_01636 2.4e-103 IQ KR domain
HOIIOEIH_01637 2.4e-14 ptsH G PTS HPr component phosphorylation site
HOIIOEIH_01638 1e-85 K Transcriptional regulator C-terminal region
HOIIOEIH_01639 1.7e-134 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HOIIOEIH_01640 2.5e-68 lrpA K transcriptional
HOIIOEIH_01641 6.1e-149 ydeK EG -transporter
HOIIOEIH_01642 3.4e-258 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOIIOEIH_01643 2.9e-67 maoC I N-terminal half of MaoC dehydratase
HOIIOEIH_01644 8e-105 ydeN S Serine hydrolase
HOIIOEIH_01645 7.5e-55 K HxlR-like helix-turn-helix
HOIIOEIH_01646 7.6e-147 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HOIIOEIH_01647 1.1e-65 ydeP K Transcriptional regulator
HOIIOEIH_01648 9.9e-106 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HOIIOEIH_01649 5.5e-48 arsR K transcriptional
HOIIOEIH_01650 1.5e-218 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HOIIOEIH_01651 3e-72 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HOIIOEIH_01652 4.6e-119 ydfB J GNAT acetyltransferase
HOIIOEIH_01653 1.2e-152 lytR K Transcriptional regulator
HOIIOEIH_01654 1.2e-130 nodB1 G deacetylase
HOIIOEIH_01655 4.7e-173
HOIIOEIH_01656 1.2e-218 T GHKL domain
HOIIOEIH_01657 4.7e-123 T Transcriptional regulatory protein, C terminal
HOIIOEIH_01658 1.4e-140 ydfC EG EamA-like transporter family
HOIIOEIH_01659 2e-261 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOIIOEIH_01660 7.7e-109 ydfE S Flavin reductase like domain
HOIIOEIH_01661 1.8e-111 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HOIIOEIH_01662 2.7e-76 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HOIIOEIH_01664 1.5e-158 ydfH 2.7.13.3 T Histidine kinase
HOIIOEIH_01665 5.1e-108 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOIIOEIH_01666 0.0 ydfJ S drug exporters of the RND superfamily
HOIIOEIH_01667 1.7e-220 K Transcriptional regulator
HOIIOEIH_01668 9e-122 azlC E AzlC protein
HOIIOEIH_01669 3.1e-48 azlD E Branched-chain amino acid transport protein (AzlD)
HOIIOEIH_01670 4.6e-212 brnQ E Component of the transport system for branched-chain amino acids
HOIIOEIH_01671 2.3e-19 rok K Repressor of ComK
HOIIOEIH_01672 6.4e-109 S Protein of unknown function (DUF554)
HOIIOEIH_01673 1.9e-136 K Bacterial transcription activator, effector binding domain
HOIIOEIH_01674 2.8e-152 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOIIOEIH_01675 6.5e-108 ydfN C nitroreductase
HOIIOEIH_01676 7.1e-183 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HOIIOEIH_01677 3.4e-62 mhqP S DoxX
HOIIOEIH_01678 9.1e-56 traF CO Thioredoxin
HOIIOEIH_01679 8.8e-25
HOIIOEIH_01680 7.2e-83 smtA 2.1.1.104 S O-methyltransferase
HOIIOEIH_01682 7.7e-68 cotP O Belongs to the small heat shock protein (HSP20) family
HOIIOEIH_01683 1.2e-33 ydgA S Spore germination protein gerPA/gerPF
HOIIOEIH_01684 3.2e-35 ydgB S Spore germination protein gerPA/gerPF
HOIIOEIH_01685 1.4e-13 K Bacterial regulatory proteins, tetR family
HOIIOEIH_01686 4e-48 K Bacterial regulatory proteins, tetR family
HOIIOEIH_01687 6.2e-44 S DoxX-like family
HOIIOEIH_01688 3.3e-80 yycN 2.3.1.128 K Acetyltransferase
HOIIOEIH_01689 1.2e-49 FG HIT domain
HOIIOEIH_01690 1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HOIIOEIH_01691 4.1e-120 purR K helix_turn _helix lactose operon repressor
HOIIOEIH_01692 1e-187 csbC EGP Major facilitator Superfamily
HOIIOEIH_01693 4e-105 G Xylose isomerase-like TIM barrel
HOIIOEIH_01694 5.2e-138 EGP Major facilitator Superfamily
HOIIOEIH_01695 2.8e-49 K Bacterial regulatory proteins, tetR family
HOIIOEIH_01696 2e-281 expZ S ABC transporter
HOIIOEIH_01697 7.1e-248 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HOIIOEIH_01698 7.8e-83 dinB S DinB family
HOIIOEIH_01699 1.5e-77 K helix_turn_helix multiple antibiotic resistance protein
HOIIOEIH_01700 0.0 ydgH S drug exporters of the RND superfamily
HOIIOEIH_01701 4e-113 drgA C nitroreductase
HOIIOEIH_01702 1.6e-68 ydgJ K Winged helix DNA-binding domain
HOIIOEIH_01703 1.5e-92 ydcN K Cupin domain
HOIIOEIH_01704 2.5e-95 azlC E branched-chain amino acid
HOIIOEIH_01705 2.5e-42 azlD S Branched-chain amino acid transport protein (AzlD)
HOIIOEIH_01706 3.8e-205 tcaB EGP Major facilitator Superfamily
HOIIOEIH_01707 2.5e-119 ydhB S membrane transporter protein
HOIIOEIH_01708 7e-116 ydhC K FCD
HOIIOEIH_01709 1.4e-231 ydhD M Glycosyl hydrolase
HOIIOEIH_01710 4.7e-216 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HOIIOEIH_01711 8.2e-115
HOIIOEIH_01712 1.6e-252 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HOIIOEIH_01713 7.2e-80 E Transglutaminase-like superfamily
HOIIOEIH_01715 9.8e-16 K Acetyltransferase (GNAT) domain
HOIIOEIH_01716 1.4e-162 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HOIIOEIH_01717 4.1e-93 ydhK M Protein of unknown function (DUF1541)
HOIIOEIH_01718 7.4e-198 pbuE EGP Major facilitator Superfamily
HOIIOEIH_01719 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HOIIOEIH_01720 7.6e-47 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HOIIOEIH_01721 1.1e-237 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOIIOEIH_01722 2.4e-267 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HOIIOEIH_01723 1.1e-130 ydhQ K UTRA
HOIIOEIH_01724 6.6e-162 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HOIIOEIH_01725 2e-177 manA 5.3.1.8 G mannose-6-phosphate isomerase
HOIIOEIH_01726 3.5e-202 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HOIIOEIH_01727 5.5e-158 ydhU P Catalase
HOIIOEIH_01730 3.4e-39 S COG NOG14552 non supervised orthologous group
HOIIOEIH_01731 7.8e-08
HOIIOEIH_01733 8.7e-168 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HOIIOEIH_01734 6.5e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HOIIOEIH_01735 3.9e-122 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HOIIOEIH_01736 1.1e-80 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HOIIOEIH_01737 5.2e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOIIOEIH_01738 1.1e-310 ydiF S ABC transporter
HOIIOEIH_01739 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HOIIOEIH_01740 3.3e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HOIIOEIH_01741 1.7e-21 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HOIIOEIH_01742 3e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HOIIOEIH_01743 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HOIIOEIH_01744 2.6e-124 ydiL S CAAX protease self-immunity
HOIIOEIH_01745 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HOIIOEIH_01746 2e-278 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HOIIOEIH_01747 2.6e-35 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HOIIOEIH_01752 9.3e-61 V abc transporter atp-binding protein
HOIIOEIH_01753 0.0 K NB-ARC domain
HOIIOEIH_01754 4.4e-197 gutB 1.1.1.14 E Dehydrogenase
HOIIOEIH_01755 4.7e-244 gutA G MFS/sugar transport protein
HOIIOEIH_01756 2.3e-168 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HOIIOEIH_01757 1.5e-110 pspA KT Phage shock protein A
HOIIOEIH_01758 1.1e-173 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOIIOEIH_01759 1.1e-122 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HOIIOEIH_01760 7.9e-145 ydjI S virion core protein (lumpy skin disease virus)
HOIIOEIH_01761 2.1e-180 S Ion transport 2 domain protein
HOIIOEIH_01762 5.4e-251 iolT EGP Major facilitator Superfamily
HOIIOEIH_01763 4.9e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HOIIOEIH_01764 1.7e-63 ydjM M Lytic transglycolase
HOIIOEIH_01765 5.2e-142 ydjN U Involved in the tonB-independent uptake of proteins
HOIIOEIH_01766 4.6e-33 ydjO S Cold-inducible protein YdjO
HOIIOEIH_01767 2.1e-151 ydjP I Alpha/beta hydrolase family
HOIIOEIH_01768 3.2e-105 yeaA S Protein of unknown function (DUF4003)
HOIIOEIH_01769 3.2e-44 yeaA S Protein of unknown function (DUF4003)
HOIIOEIH_01770 4.4e-307 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HOIIOEIH_01771 2.1e-247 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HOIIOEIH_01772 6.6e-151 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOIIOEIH_01773 1e-168 yeaC S COG0714 MoxR-like ATPases
HOIIOEIH_01774 1.9e-204 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HOIIOEIH_01775 0.0 yebA E COG1305 Transglutaminase-like enzymes
HOIIOEIH_01776 1.9e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HOIIOEIH_01777 1.5e-210 pbuG S permease
HOIIOEIH_01778 2e-109 yebC M Membrane
HOIIOEIH_01780 1.2e-92 yebE S UPF0316 protein
HOIIOEIH_01781 8e-28 yebG S NETI protein
HOIIOEIH_01782 6.9e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HOIIOEIH_01783 5.4e-209 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HOIIOEIH_01784 2.4e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HOIIOEIH_01785 2.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HOIIOEIH_01786 4.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOIIOEIH_01787 7.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOIIOEIH_01788 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOIIOEIH_01789 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOIIOEIH_01790 3.9e-174 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HOIIOEIH_01791 3.8e-102 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HOIIOEIH_01792 6.2e-285 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HOIIOEIH_01793 7.2e-231 purD 6.3.4.13 F Belongs to the GARS family
HOIIOEIH_01794 2.4e-69 K helix_turn_helix ASNC type
HOIIOEIH_01795 2.1e-214 yjeH E Amino acid permease
HOIIOEIH_01796 6.6e-29 S Protein of unknown function (DUF2892)
HOIIOEIH_01797 0.0 yerA 3.5.4.2 F adenine deaminase
HOIIOEIH_01798 6.8e-184 yerB S Protein of unknown function (DUF3048) C-terminal domain
HOIIOEIH_01799 4.8e-51 yerC S protein conserved in bacteria
HOIIOEIH_01800 2.6e-294 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HOIIOEIH_01801 3.5e-123 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HOIIOEIH_01802 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HOIIOEIH_01803 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOIIOEIH_01804 2.5e-217 camS S COG4851 Protein involved in sex pheromone biosynthesis
HOIIOEIH_01805 1.6e-180 yerI S homoserine kinase type II (protein kinase fold)
HOIIOEIH_01806 8.8e-122 sapB S MgtC SapB transporter
HOIIOEIH_01807 2.4e-246 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOIIOEIH_01808 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOIIOEIH_01809 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HOIIOEIH_01810 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOIIOEIH_01811 2.3e-140 yerO K Transcriptional regulator
HOIIOEIH_01812 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HOIIOEIH_01813 2.5e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HOIIOEIH_01814 5.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOIIOEIH_01815 2.6e-86 S Protein of unknown function (DUF4007)
HOIIOEIH_01816 0.0 S COG0433 Predicted ATPase
HOIIOEIH_01817 1.4e-116 EH sulfate reduction
HOIIOEIH_01818 2.1e-228 KLT serine threonine protein kinase
HOIIOEIH_01819 8.6e-218
HOIIOEIH_01820 0.0 ftsK D FtsK/SpoIIIE family
HOIIOEIH_01822 8.9e-37
HOIIOEIH_01823 6.3e-153 L nucleic acid phosphodiester bond hydrolysis
HOIIOEIH_01824 4.4e-170 3.4.24.40 CO amine dehydrogenase activity
HOIIOEIH_01825 8.4e-54
HOIIOEIH_01826 9.7e-31
HOIIOEIH_01827 2.9e-199 S Tetratricopeptide repeat
HOIIOEIH_01829 5e-126 yeeN K transcriptional regulatory protein
HOIIOEIH_01831 6.3e-97 dhaR3 K Transcriptional regulator
HOIIOEIH_01832 1.3e-78 yesE S SnoaL-like domain
HOIIOEIH_01833 8.7e-140 yesF GM NAD(P)H-binding
HOIIOEIH_01834 5.9e-44 cotJA S Spore coat associated protein JA (CotJA)
HOIIOEIH_01835 1.3e-44 cotJB S CotJB protein
HOIIOEIH_01836 8.9e-104 cotJC P Spore Coat
HOIIOEIH_01837 2.9e-96 yesJ K Acetyltransferase (GNAT) family
HOIIOEIH_01838 3.5e-93 yesL S Protein of unknown function, DUF624
HOIIOEIH_01839 9e-301 yesM 2.7.13.3 T Histidine kinase
HOIIOEIH_01840 8e-194 yesN K helix_turn_helix, arabinose operon control protein
HOIIOEIH_01841 7e-242 yesO G Bacterial extracellular solute-binding protein
HOIIOEIH_01842 1.1e-164 yesP G Binding-protein-dependent transport system inner membrane component
HOIIOEIH_01843 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
HOIIOEIH_01844 6.8e-195 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HOIIOEIH_01845 0.0 yesS K Transcriptional regulator
HOIIOEIH_01846 4.5e-126 E GDSL-like Lipase/Acylhydrolase
HOIIOEIH_01847 1.4e-124 yesU S Domain of unknown function (DUF1961)
HOIIOEIH_01848 9.1e-110 yesV S Protein of unknown function, DUF624
HOIIOEIH_01849 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HOIIOEIH_01850 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HOIIOEIH_01851 2.2e-122 yesY E GDSL-like Lipase/Acylhydrolase
HOIIOEIH_01852 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HOIIOEIH_01853 0.0 yetA
HOIIOEIH_01854 1.3e-284 lplA G Bacterial extracellular solute-binding protein
HOIIOEIH_01855 2.1e-174 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HOIIOEIH_01856 1.1e-161 lplC G Binding-protein-dependent transport system inner membrane component
HOIIOEIH_01857 2.4e-232 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HOIIOEIH_01858 1.2e-107 yetF S membrane
HOIIOEIH_01859 5.8e-52 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HOIIOEIH_01860 4.5e-61 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOIIOEIH_01861 2.5e-31
HOIIOEIH_01862 9.3e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HOIIOEIH_01863 3.4e-19 yezD S Uncharacterized small protein (DUF2292)
HOIIOEIH_01864 7.7e-104 yetJ S Belongs to the BI1 family
HOIIOEIH_01865 3.8e-139 yetK EG EamA-like transporter family
HOIIOEIH_01866 2e-67 yetL K helix_turn_helix multiple antibiotic resistance protein
HOIIOEIH_01867 1.1e-198 yetM CH FAD binding domain
HOIIOEIH_01868 8.3e-196 yetN S Protein of unknown function (DUF3900)
HOIIOEIH_01869 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HOIIOEIH_01870 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HOIIOEIH_01871 1.9e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
HOIIOEIH_01872 4.6e-171 yfnG 4.2.1.45 M dehydratase
HOIIOEIH_01873 8.7e-178 yfnF M Nucleotide-diphospho-sugar transferase
HOIIOEIH_01874 1.6e-216 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HOIIOEIH_01875 8.3e-184 yfnD M Nucleotide-diphospho-sugar transferase
HOIIOEIH_01876 2.5e-204 fsr P COG0477 Permeases of the major facilitator superfamily
HOIIOEIH_01877 2.7e-118 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HOIIOEIH_01878 3.7e-236 yfnA E amino acid
HOIIOEIH_01879 1.4e-275 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HOIIOEIH_01880 3.5e-112 yfmS NT chemotaxis protein
HOIIOEIH_01881 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HOIIOEIH_01882 1.4e-67 yfmQ S Uncharacterised protein from bacillus cereus group
HOIIOEIH_01883 6.2e-70 yfmP K transcriptional
HOIIOEIH_01884 4.7e-208 yfmO EGP Major facilitator Superfamily
HOIIOEIH_01885 3.7e-91 yhfO K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOIIOEIH_01886 6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HOIIOEIH_01887 1.1e-195 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HOIIOEIH_01888 5e-52 yfmK 2.3.1.128 K acetyltransferase
HOIIOEIH_01889 1.4e-181 yfmJ S N-terminal domain of oxidoreductase
HOIIOEIH_01890 4.8e-148 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HOIIOEIH_01891 2.8e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_01892 4.4e-167 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_01893 5.1e-165 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HOIIOEIH_01894 1e-23 S Protein of unknown function (DUF3212)
HOIIOEIH_01895 4.2e-56 yflT S Heat induced stress protein YflT
HOIIOEIH_01896 4.1e-234 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HOIIOEIH_01897 8.7e-233 yflS P Sodium:sulfate symporter transmembrane region
HOIIOEIH_01898 4.4e-262 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HOIIOEIH_01899 8.1e-112 citT T response regulator
HOIIOEIH_01900 2.3e-168 yflP S Tripartite tricarboxylate transporter family receptor
HOIIOEIH_01901 8.5e-227 citM C Citrate transporter
HOIIOEIH_01902 1.6e-143 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HOIIOEIH_01903 1.6e-210 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HOIIOEIH_01904 1.4e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HOIIOEIH_01905 1.9e-110 yflK S protein conserved in bacteria
HOIIOEIH_01906 3.6e-16 yflJ S Protein of unknown function (DUF2639)
HOIIOEIH_01907 1.5e-20 yflI
HOIIOEIH_01908 1.8e-45 yflH S Protein of unknown function (DUF3243)
HOIIOEIH_01909 4.2e-138 map 3.4.11.18 E Methionine aminopeptidase
HOIIOEIH_01910 2e-247 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HOIIOEIH_01911 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HOIIOEIH_01912 2e-62 yhdN S Domain of unknown function (DUF1992)
HOIIOEIH_01913 1.4e-246 agcS_1 E Sodium alanine symporter
HOIIOEIH_01914 1.1e-35 E Spore germination protein
HOIIOEIH_01915 3e-54 yfkQ EG Spore germination protein
HOIIOEIH_01916 1.2e-253 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOIIOEIH_01917 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HOIIOEIH_01918 1.3e-131 treR K transcriptional
HOIIOEIH_01919 1.2e-123 yfkO C nitroreductase
HOIIOEIH_01920 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HOIIOEIH_01921 2.1e-88 yfkM 3.5.1.124 S protease
HOIIOEIH_01922 3.7e-197 ydiM EGP Major facilitator Superfamily
HOIIOEIH_01923 3e-28 yfkK S Belongs to the UPF0435 family
HOIIOEIH_01924 6.7e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOIIOEIH_01925 2.7e-49 yfkI S gas vesicle protein
HOIIOEIH_01926 1.1e-139 yihY S Belongs to the UPF0761 family
HOIIOEIH_01928 5.7e-214 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HOIIOEIH_01929 3.8e-177 cax P COG0387 Ca2 H antiporter
HOIIOEIH_01930 3.9e-142 yfkD S YfkD-like protein
HOIIOEIH_01931 3.3e-147 yfkC M Mechanosensitive ion channel
HOIIOEIH_01932 4.3e-219 yfkA S YfkB-like domain
HOIIOEIH_01933 1.1e-26 yfjT
HOIIOEIH_01934 4.9e-153 pdaA G deacetylase
HOIIOEIH_01935 3.6e-142 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HOIIOEIH_01936 1e-181 corA P Mediates influx of magnesium ions
HOIIOEIH_01937 1.3e-159 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HOIIOEIH_01938 1.9e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOIIOEIH_01939 2e-188 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOIIOEIH_01941 9.8e-117 msbA2 3.6.3.44 V ABC transporter
HOIIOEIH_01942 2.5e-13 abgA S Peptidase dimerisation domain
HOIIOEIH_01943 6.4e-15 abgA S Peptidase dimerisation domain
HOIIOEIH_01944 2.7e-76 ydaF_2 2.3.1.128 J Acetyltransferases including N-acetylases of ribosomal proteins
HOIIOEIH_01945 3.5e-79 yfjM S Psort location Cytoplasmic, score
HOIIOEIH_01946 2e-25 yfjL
HOIIOEIH_01947 3.2e-189 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HOIIOEIH_01948 1.2e-186 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HOIIOEIH_01949 1.4e-188 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HOIIOEIH_01950 5.1e-246 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HOIIOEIH_01951 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HOIIOEIH_01952 1.2e-22 sspH S Belongs to the SspH family
HOIIOEIH_01953 2.4e-53 yfjF S UPF0060 membrane protein
HOIIOEIH_01954 1.9e-87 S Family of unknown function (DUF5381)
HOIIOEIH_01955 5.7e-130 yfjC
HOIIOEIH_01956 4.8e-163 yfjB
HOIIOEIH_01957 2.2e-43 yfjA S Belongs to the WXG100 family
HOIIOEIH_01958 2.1e-260 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HOIIOEIH_01959 6.9e-136 glvR K Helix-turn-helix domain, rpiR family
HOIIOEIH_01960 9.8e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HOIIOEIH_01961 1.2e-297 yfiB3 V ABC transporter
HOIIOEIH_01962 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HOIIOEIH_01963 3e-61 mhqP S DoxX
HOIIOEIH_01964 3.1e-153 yfiE 1.13.11.2 S glyoxalase
HOIIOEIH_01965 1.9e-185 T Histidine kinase
HOIIOEIH_01966 2e-107 KT LuxR family transcriptional regulator
HOIIOEIH_01967 2.7e-166 V ABC transporter, ATP-binding protein
HOIIOEIH_01968 2.8e-192 V ABC-2 family transporter protein
HOIIOEIH_01969 3.9e-183 V COG0842 ABC-type multidrug transport system, permease component
HOIIOEIH_01970 3.3e-69 J Acetyltransferase (GNAT) domain
HOIIOEIH_01971 8.5e-96 padR K transcriptional
HOIIOEIH_01972 4.8e-74 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HOIIOEIH_01973 1.5e-192 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HOIIOEIH_01974 4.6e-94 yfiT S Belongs to the metal hydrolase YfiT family
HOIIOEIH_01975 2.3e-279 yfiU EGP Major facilitator Superfamily
HOIIOEIH_01976 9.2e-78 yfiV K transcriptional
HOIIOEIH_01977 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HOIIOEIH_01978 5.1e-176 yfiY P ABC transporter substrate-binding protein
HOIIOEIH_01979 3.8e-166 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_01980 3.7e-169 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOIIOEIH_01981 6.9e-156 yfhB 5.3.3.17 S PhzF family
HOIIOEIH_01982 9.1e-104 yfhC C nitroreductase
HOIIOEIH_01983 1.8e-24 yfhD S YfhD-like protein
HOIIOEIH_01985 7.9e-163 yfhF S nucleoside-diphosphate sugar epimerase
HOIIOEIH_01986 1.8e-134 recX 2.4.1.337 GT4 S Modulates RecA activity
HOIIOEIH_01987 1e-48 yfhH S Protein of unknown function (DUF1811)
HOIIOEIH_01988 1.3e-205 yfhI EGP Major facilitator Superfamily
HOIIOEIH_01989 6.2e-20 sspK S reproduction
HOIIOEIH_01990 2.7e-42 yfhJ S WVELL protein
HOIIOEIH_01991 1.6e-80 batE T Bacterial SH3 domain homologues
HOIIOEIH_01992 9.6e-49 yfhL S SdpI/YhfL protein family
HOIIOEIH_01993 2.4e-161 yfhM S Alpha beta hydrolase
HOIIOEIH_01994 1.7e-182 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HOIIOEIH_01995 0.0 yfhO S Bacterial membrane protein YfhO
HOIIOEIH_01996 6.1e-185 yfhP S membrane-bound metal-dependent
HOIIOEIH_01997 3e-204 mutY L A G-specific
HOIIOEIH_01998 2e-35 yfhS
HOIIOEIH_01999 4.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOIIOEIH_02000 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HOIIOEIH_02001 5.6e-37 ygaB S YgaB-like protein
HOIIOEIH_02002 1.3e-104 ygaC J Belongs to the UPF0374 family
HOIIOEIH_02003 3.6e-297 ygaD V ABC transporter
HOIIOEIH_02004 8.1e-178 ygaE S Membrane
HOIIOEIH_02005 1.6e-241 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HOIIOEIH_02006 1.4e-86 bcp 1.11.1.15 O Peroxiredoxin
HOIIOEIH_02007 4e-80 perR P Belongs to the Fur family
HOIIOEIH_02008 2.8e-55 ygzB S UPF0295 protein
HOIIOEIH_02009 1.7e-162 ygxA S Nucleotidyltransferase-like
HOIIOEIH_02010 3.4e-39 S COG NOG14552 non supervised orthologous group
HOIIOEIH_02015 7.8e-08
HOIIOEIH_02023 2e-08
HOIIOEIH_02027 4.4e-138 spo0M S COG4326 Sporulation control protein
HOIIOEIH_02028 1.7e-25
HOIIOEIH_02029 3.8e-14 yraF M Spore coat protein
HOIIOEIH_02030 2.8e-114 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HOIIOEIH_02031 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HOIIOEIH_02033 1.3e-287 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HOIIOEIH_02034 3.7e-157 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HOIIOEIH_02035 1.3e-163 ssuA M Sulfonate ABC transporter
HOIIOEIH_02036 2e-144 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HOIIOEIH_02037 4.2e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HOIIOEIH_02039 6.6e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOIIOEIH_02040 7.4e-72 ygaO
HOIIOEIH_02041 3.7e-28 K Transcriptional regulator
HOIIOEIH_02043 1.3e-108 yhzB S B3/4 domain
HOIIOEIH_02044 6.2e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HOIIOEIH_02045 6.3e-168 yhbB S Putative amidase domain
HOIIOEIH_02046 5.9e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HOIIOEIH_02047 1.6e-101 yhbD K Protein of unknown function (DUF4004)
HOIIOEIH_02048 1.7e-59 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HOIIOEIH_02049 2.1e-62 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HOIIOEIH_02050 0.0 prkA T Ser protein kinase
HOIIOEIH_02051 1.6e-224 yhbH S Belongs to the UPF0229 family
HOIIOEIH_02052 1e-73 yhbI K DNA-binding transcription factor activity
HOIIOEIH_02053 5.8e-96 yhbJ V COG1566 Multidrug resistance efflux pump
HOIIOEIH_02054 3.5e-283 yhcA EGP Major facilitator Superfamily
HOIIOEIH_02055 1.3e-96 yhcB 1.6.5.2 S Belongs to the WrbA family
HOIIOEIH_02056 8.3e-34 yhcC
HOIIOEIH_02057 1.6e-53
HOIIOEIH_02058 2.6e-56 yhcF K Transcriptional regulator
HOIIOEIH_02059 1.3e-117 yhcG V ABC transporter, ATP-binding protein
HOIIOEIH_02060 4.2e-156 yhcH V ABC transporter, ATP-binding protein
HOIIOEIH_02061 1.4e-154 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HOIIOEIH_02062 1e-30 cspB K Cold-shock protein
HOIIOEIH_02063 4.1e-142 metQ M Belongs to the nlpA lipoprotein family
HOIIOEIH_02064 3.5e-186 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HOIIOEIH_02065 1.8e-214 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOIIOEIH_02066 1.2e-36 yhcM
HOIIOEIH_02067 1.5e-66 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HOIIOEIH_02068 1e-152 yhcP
HOIIOEIH_02069 2.4e-97 yhcQ M Spore coat protein
HOIIOEIH_02070 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HOIIOEIH_02071 1.4e-96 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HOIIOEIH_02072 1.2e-158 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HOIIOEIH_02073 1.9e-65 yhcU S Family of unknown function (DUF5365)
HOIIOEIH_02074 1.2e-65 yhcV S COG0517 FOG CBS domain
HOIIOEIH_02075 4e-116 yhcW 5.4.2.6 S hydrolase
HOIIOEIH_02076 3.5e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HOIIOEIH_02077 4.2e-148 S Membrane transport protein
HOIIOEIH_02078 8.6e-259 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOIIOEIH_02079 2.4e-101 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HOIIOEIH_02080 7.4e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HOIIOEIH_02081 1.9e-291 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HOIIOEIH_02082 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HOIIOEIH_02083 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HOIIOEIH_02084 5e-199 yhcY 2.7.13.3 T Histidine kinase
HOIIOEIH_02085 1e-103 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOIIOEIH_02086 4.8e-80 azr 1.7.1.6 S NADPH-dependent FMN reductase
HOIIOEIH_02087 2.8e-38 yhdB S YhdB-like protein
HOIIOEIH_02088 3.8e-51 yhdC S Protein of unknown function (DUF3889)
HOIIOEIH_02089 1.2e-173 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HOIIOEIH_02090 1.5e-74 nsrR K Transcriptional regulator
HOIIOEIH_02091 5.6e-230 ygxB M Conserved TM helix
HOIIOEIH_02092 1.7e-273 ycgB S Stage V sporulation protein R
HOIIOEIH_02093 3.1e-251 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HOIIOEIH_02094 1.2e-130 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HOIIOEIH_02095 3e-159 citR K Transcriptional regulator
HOIIOEIH_02096 5e-196 citA 2.3.3.1 C Belongs to the citrate synthase family
HOIIOEIH_02097 6.2e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOIIOEIH_02098 3.8e-249 yhdG E amino acid
HOIIOEIH_02099 9.4e-229 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HOIIOEIH_02100 9.8e-237 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOIIOEIH_02101 7.9e-73 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOIIOEIH_02102 8.1e-45 yhdK S Sigma-M inhibitor protein
HOIIOEIH_02103 3.4e-197 yhdL S Sigma factor regulator N-terminal
HOIIOEIH_02104 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HOIIOEIH_02105 5e-179 yhdN C Aldo keto reductase
HOIIOEIH_02106 1.7e-105 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HOIIOEIH_02107 9.4e-174 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HOIIOEIH_02108 1.3e-165 galE 5.1.3.2 GM GDP-mannose 4,6 dehydratase
HOIIOEIH_02109 2.8e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HOIIOEIH_02110 6.8e-74 cueR K transcriptional
HOIIOEIH_02111 3.7e-213 yhdR 2.6.1.1 E Aminotransferase
HOIIOEIH_02112 2.5e-237 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HOIIOEIH_02113 7.4e-40 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOIIOEIH_02114 4.8e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOIIOEIH_02115 1.5e-124 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HOIIOEIH_02117 2.7e-197 yhdY M Mechanosensitive ion channel
HOIIOEIH_02118 1.7e-131 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HOIIOEIH_02119 6.5e-135 yheN G deacetylase
HOIIOEIH_02120 1.8e-145 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HOIIOEIH_02121 5.2e-219 nhaC C Na H antiporter
HOIIOEIH_02122 6.4e-82 nhaX T Belongs to the universal stress protein A family
HOIIOEIH_02123 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HOIIOEIH_02124 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HOIIOEIH_02125 6.1e-98 yheG GM NAD(P)H-binding
HOIIOEIH_02126 6.3e-28 sspB S spore protein
HOIIOEIH_02127 2.5e-35 yheE S Family of unknown function (DUF5342)
HOIIOEIH_02128 2.5e-253 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HOIIOEIH_02129 5.8e-213 yheC HJ YheC/D like ATP-grasp
HOIIOEIH_02130 1.7e-191 yheB S Belongs to the UPF0754 family
HOIIOEIH_02131 9.5e-48 yheA S Belongs to the UPF0342 family
HOIIOEIH_02132 8.2e-187 yhaZ L DNA alkylation repair enzyme
HOIIOEIH_02133 1.1e-140 yhaX S haloacid dehalogenase-like hydrolase
HOIIOEIH_02134 1.2e-285 hemZ H coproporphyrinogen III oxidase
HOIIOEIH_02135 2.4e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
HOIIOEIH_02136 1e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HOIIOEIH_02138 1.3e-126 yhaR 5.3.3.18 I enoyl-CoA hydratase
HOIIOEIH_02139 6.2e-22 S YhzD-like protein
HOIIOEIH_02140 1.3e-162 yhaQ S ABC transporter, ATP-binding protein
HOIIOEIH_02141 4.8e-211 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HOIIOEIH_02142 2.2e-213 yhaO L DNA repair exonuclease
HOIIOEIH_02143 0.0 yhaN L AAA domain
HOIIOEIH_02144 1.4e-175 yhaM L Shows a 3'-5' exoribonuclease activity
HOIIOEIH_02145 5.1e-20 yhaL S Sporulation protein YhaL
HOIIOEIH_02146 4e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HOIIOEIH_02147 7.3e-89 yhaK S Putative zincin peptidase
HOIIOEIH_02148 1.6e-52 yhaI S Protein of unknown function (DUF1878)
HOIIOEIH_02149 3.9e-113 hpr K Negative regulator of protease production and sporulation
HOIIOEIH_02150 1e-37 yhaH S YtxH-like protein
HOIIOEIH_02151 9.5e-20
HOIIOEIH_02152 1.7e-77 trpP S Tryptophan transporter TrpP
HOIIOEIH_02153 5.6e-200 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HOIIOEIH_02154 2.6e-79 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HOIIOEIH_02155 4.6e-137 ecsA V transporter (ATP-binding protein)
HOIIOEIH_02156 2.7e-198 ecsB U ABC transporter
HOIIOEIH_02157 5.1e-109 ecsC S EcsC protein family
HOIIOEIH_02158 7.5e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HOIIOEIH_02159 6.5e-233 yhfA C membrane
HOIIOEIH_02160 2.4e-84 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HOIIOEIH_02161 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HOIIOEIH_02162 9.4e-200 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HOIIOEIH_02163 1.3e-176 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HOIIOEIH_02164 1.3e-260 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HOIIOEIH_02165 1.3e-99 yhgD K Transcriptional regulator
HOIIOEIH_02166 3.5e-215 yhgE S YhgE Pip N-terminal domain protein
HOIIOEIH_02167 9.6e-175 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOIIOEIH_02168 1e-126 yhfC S Putative membrane peptidase family (DUF2324)
HOIIOEIH_02169 1.2e-196 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HOIIOEIH_02170 1e-69 3.4.13.21 S ASCH
HOIIOEIH_02171 6.7e-224 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOIIOEIH_02172 6.4e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HOIIOEIH_02173 1.2e-185 lplJ 6.3.1.20 H Lipoate-protein ligase
HOIIOEIH_02174 9.7e-107 yhfK GM NmrA-like family
HOIIOEIH_02175 4.1e-292 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HOIIOEIH_02176 1.8e-63 yhfM
HOIIOEIH_02177 5e-232 yhfN 3.4.24.84 O Peptidase M48
HOIIOEIH_02178 5.4e-201 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HOIIOEIH_02179 3.1e-67 VY92_01935 K acetyltransferase
HOIIOEIH_02180 3.7e-174 yhfP 1.1.1.1 C Quinone oxidoreductase
HOIIOEIH_02181 4.6e-153 yfmC M Periplasmic binding protein
HOIIOEIH_02182 9.7e-106 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HOIIOEIH_02183 1.9e-179 vraB 2.3.1.9 I Belongs to the thiolase family
HOIIOEIH_02184 6.2e-247 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HOIIOEIH_02185 3e-88 bioY S BioY family
HOIIOEIH_02186 5.6e-178 hemAT NT chemotaxis protein
HOIIOEIH_02187 8.5e-295 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HOIIOEIH_02188 1.1e-155 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOIIOEIH_02189 2.4e-31 yhzC S IDEAL
HOIIOEIH_02190 1e-107 comK K Competence transcription factor
HOIIOEIH_02191 1.1e-161 IQ Enoyl-(Acyl carrier protein) reductase
HOIIOEIH_02192 9.5e-40 yhjA S Excalibur calcium-binding domain
HOIIOEIH_02193 3e-257 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOIIOEIH_02194 2e-26 yhjC S Protein of unknown function (DUF3311)
HOIIOEIH_02195 5.7e-56 yhjD
HOIIOEIH_02196 1e-108 yhjE S SNARE associated Golgi protein
HOIIOEIH_02197 1.9e-89 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HOIIOEIH_02198 2.9e-255 yhjG CH FAD binding domain
HOIIOEIH_02199 1.5e-89 yhjH K helix_turn_helix multiple antibiotic resistance protein
HOIIOEIH_02201 2.9e-205 glcP G Major Facilitator Superfamily
HOIIOEIH_02202 3.4e-194 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HOIIOEIH_02203 1.3e-154 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HOIIOEIH_02204 5.6e-242 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HOIIOEIH_02205 2.6e-183 yhjM 5.1.1.1 K Transcriptional regulator
HOIIOEIH_02206 1.5e-195 abrB S membrane
HOIIOEIH_02207 1.9e-196 EGP Transmembrane secretion effector
HOIIOEIH_02208 4.6e-305 S Sugar transport-related sRNA regulator N-term
HOIIOEIH_02209 2.3e-17 yhjQ C COG1145 Ferredoxin
HOIIOEIH_02210 6.2e-73 yhjR S Rubrerythrin
HOIIOEIH_02211 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HOIIOEIH_02212 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HOIIOEIH_02213 1.1e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HOIIOEIH_02214 0.0 sbcC L COG0419 ATPase involved in DNA repair
HOIIOEIH_02215 6.2e-48 yisB V COG1403 Restriction endonuclease
HOIIOEIH_02216 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HOIIOEIH_02217 2.1e-59 gerPE S Spore germination protein GerPE
HOIIOEIH_02218 2.6e-22 gerPD S Spore germination protein
HOIIOEIH_02219 5.5e-51 gerPC S Spore germination protein
HOIIOEIH_02220 1.5e-33 gerPB S cell differentiation
HOIIOEIH_02221 1.2e-32 gerPA S Spore germination protein
HOIIOEIH_02222 5.8e-14 yisI S Spo0E like sporulation regulatory protein
HOIIOEIH_02223 8e-147 cotH M Spore Coat
HOIIOEIH_02224 4.3e-169 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HOIIOEIH_02225 7.3e-56 yisL S UPF0344 protein
HOIIOEIH_02226 0.0 wprA O Belongs to the peptidase S8 family
HOIIOEIH_02227 1.9e-98 yisN S Protein of unknown function (DUF2777)
HOIIOEIH_02228 0.0 asnO 6.3.5.4 E Asparagine synthase
HOIIOEIH_02229 3.9e-113 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HOIIOEIH_02230 1.6e-239 yisQ V Mate efflux family protein
HOIIOEIH_02231 2.3e-159 yisR K Transcriptional regulator
HOIIOEIH_02232 6.3e-177 purR K helix_turn _helix lactose operon repressor
HOIIOEIH_02233 4e-187 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HOIIOEIH_02234 5.9e-83 yisT S DinB family
HOIIOEIH_02235 1.7e-100 argO S Lysine exporter protein LysE YggA
HOIIOEIH_02236 2.9e-260 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOIIOEIH_02237 1.8e-28 mcbG S Pentapeptide repeats (9 copies)
HOIIOEIH_02238 1.2e-146 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HOIIOEIH_02239 1.3e-105 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HOIIOEIH_02240 8.2e-221 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HOIIOEIH_02241 7.4e-132 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HOIIOEIH_02242 1.3e-109 comB 3.1.3.71 H Belongs to the ComB family
HOIIOEIH_02243 6.8e-136 yitD 4.4.1.19 S synthase
HOIIOEIH_02244 6.1e-106 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOIIOEIH_02245 5.6e-203 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HOIIOEIH_02246 1.2e-225 yitG EGP Major facilitator Superfamily
HOIIOEIH_02247 5e-135 yitH K Acetyltransferase (GNAT) domain
HOIIOEIH_02248 1.1e-72 yjcF S Acetyltransferase (GNAT) domain
HOIIOEIH_02249 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HOIIOEIH_02250 5.6e-54 yajQ S Belongs to the UPF0234 family
HOIIOEIH_02251 2.3e-156 cvfB S protein conserved in bacteria
HOIIOEIH_02252 1.2e-35 yitR S Domain of unknown function (DUF3784)
HOIIOEIH_02253 7.9e-149 yitS S protein conserved in bacteria
HOIIOEIH_02254 2.1e-146 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HOIIOEIH_02255 5.8e-74 ipi S Intracellular proteinase inhibitor
HOIIOEIH_02256 3.4e-26 S Protein of unknown function (DUF3813)
HOIIOEIH_02258 2.5e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HOIIOEIH_02259 6.3e-137 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HOIIOEIH_02260 8e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HOIIOEIH_02261 1.5e-22 pilT S Proteolipid membrane potential modulator
HOIIOEIH_02262 2.7e-258 yitY C D-arabinono-1,4-lactone oxidase
HOIIOEIH_02263 2.6e-89 norB G Major Facilitator Superfamily
HOIIOEIH_02264 2.1e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HOIIOEIH_02265 6.5e-221 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HOIIOEIH_02266 5.6e-133 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HOIIOEIH_02267 2e-211 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HOIIOEIH_02268 2.9e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HOIIOEIH_02269 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HOIIOEIH_02270 2.3e-168 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HOIIOEIH_02271 9.5e-28 yjzC S YjzC-like protein
HOIIOEIH_02272 2.1e-17 yjzD S Protein of unknown function (DUF2929)
HOIIOEIH_02273 1.9e-135 yjaU I carboxylic ester hydrolase activity
HOIIOEIH_02274 1.1e-90 yjaV
HOIIOEIH_02275 9.7e-180 med S Transcriptional activator protein med
HOIIOEIH_02276 7.3e-26 comZ S ComZ
HOIIOEIH_02277 1.1e-25 yjzB
HOIIOEIH_02278 2.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOIIOEIH_02279 1.7e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HOIIOEIH_02280 4e-139 yjaZ O Zn-dependent protease
HOIIOEIH_02281 5.1e-184 appD P Belongs to the ABC transporter superfamily
HOIIOEIH_02282 2.3e-184 appF E Belongs to the ABC transporter superfamily
HOIIOEIH_02283 1.3e-272 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HOIIOEIH_02284 3.8e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOIIOEIH_02285 8.8e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOIIOEIH_02286 8.6e-147 yjbA S Belongs to the UPF0736 family
HOIIOEIH_02287 2.8e-182 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HOIIOEIH_02288 3.4e-305 oppA E ABC transporter substrate-binding protein
HOIIOEIH_02289 1.5e-164 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOIIOEIH_02290 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOIIOEIH_02291 1.5e-197 oppD P Belongs to the ABC transporter superfamily
HOIIOEIH_02292 6.7e-170 oppF E Belongs to the ABC transporter superfamily
HOIIOEIH_02293 7.3e-179 yjbB EGP Major Facilitator Superfamily
HOIIOEIH_02294 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOIIOEIH_02295 1.7e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HOIIOEIH_02296 7.3e-110 yjbE P Integral membrane protein TerC family
HOIIOEIH_02297 2.9e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HOIIOEIH_02298 6.2e-197 yjbF S Competence protein
HOIIOEIH_02299 0.0 pepF E oligoendopeptidase F
HOIIOEIH_02300 3.7e-18
HOIIOEIH_02301 2.6e-166 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HOIIOEIH_02302 8.2e-72 yjbI S Bacterial-like globin
HOIIOEIH_02303 8.2e-102 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HOIIOEIH_02304 1.8e-96 yjbK S protein conserved in bacteria
HOIIOEIH_02305 2.8e-58 yjbL S Belongs to the UPF0738 family
HOIIOEIH_02306 1.7e-111 yjbM 2.7.6.5 S GTP pyrophosphokinase
HOIIOEIH_02307 4.7e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOIIOEIH_02308 1.9e-148 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HOIIOEIH_02309 6.9e-125 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HOIIOEIH_02310 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HOIIOEIH_02311 1e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HOIIOEIH_02312 1.1e-102 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HOIIOEIH_02313 9.2e-206 thiO 1.4.3.19 E Glycine oxidase
HOIIOEIH_02314 3.3e-29 thiS H thiamine diphosphate biosynthetic process
HOIIOEIH_02315 2.2e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HOIIOEIH_02316 2.2e-182 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HOIIOEIH_02317 7.3e-144 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HOIIOEIH_02318 4.7e-140 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HOIIOEIH_02319 2.8e-48 yjbX S Spore coat protein
HOIIOEIH_02320 5.6e-77 cotZ S Spore coat protein
HOIIOEIH_02321 1.3e-95 cotY S Spore coat protein Z
HOIIOEIH_02322 1.2e-67 cotX S Spore Coat Protein X and V domain
HOIIOEIH_02323 2.3e-24 cotW
HOIIOEIH_02324 1.1e-52 cotV S Spore Coat Protein X and V domain
HOIIOEIH_02325 7.3e-56 yjcA S Protein of unknown function (DUF1360)
HOIIOEIH_02328 6.4e-38 spoVIF S Stage VI sporulation protein F
HOIIOEIH_02329 0.0 yjcD 3.6.4.12 L DNA helicase
HOIIOEIH_02330 2.7e-36
HOIIOEIH_02331 4.8e-70 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOIIOEIH_02332 1.6e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HOIIOEIH_02333 1e-133 yjcH P COG2382 Enterochelin esterase and related enzymes
HOIIOEIH_02334 8.7e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HOIIOEIH_02335 4.1e-212 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HOIIOEIH_02336 1.1e-90 rimJ 2.3.1.128 J Alanine acetyltransferase
HOIIOEIH_02337 4.1e-204 yjcL S Protein of unknown function (DUF819)
HOIIOEIH_02339 8.3e-40
HOIIOEIH_02345 2.8e-22 V HNH endonuclease
HOIIOEIH_02346 3.2e-11 yokH G SMI1 / KNR4 family
HOIIOEIH_02347 3.4e-59 yokH G SMI1 / KNR4 family
HOIIOEIH_02348 6e-45 yjcS S Antibiotic biosynthesis monooxygenase
HOIIOEIH_02349 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HOIIOEIH_02350 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HOIIOEIH_02351 1.2e-166 manA 5.3.1.8 G mannose-6-phosphate isomerase
HOIIOEIH_02353 1.4e-76 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HOIIOEIH_02355 2e-72 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOIIOEIH_02356 4.6e-28 S Domain of unknown function (DUF4177)
HOIIOEIH_02358 2.7e-169 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HOIIOEIH_02360 1.3e-254 xynD 3.5.1.104 G Polysaccharide deacetylase
HOIIOEIH_02361 6.7e-81 S Protein of unknown function (DUF2690)
HOIIOEIH_02362 2.6e-19 yjfB S Putative motility protein
HOIIOEIH_02363 2.5e-153 yjfC O Predicted Zn-dependent protease (DUF2268)
HOIIOEIH_02364 7.8e-60 T PhoQ Sensor
HOIIOEIH_02365 7.4e-90 yjgB S Domain of unknown function (DUF4309)
HOIIOEIH_02366 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HOIIOEIH_02367 1.2e-92 yjgD S Protein of unknown function (DUF1641)
HOIIOEIH_02368 1.3e-09 S Domain of unknown function (DUF4352)
HOIIOEIH_02369 9.9e-101 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HOIIOEIH_02371 4.1e-212 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HOIIOEIH_02372 1.2e-206 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HOIIOEIH_02373 1.8e-29
HOIIOEIH_02374 2.2e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HOIIOEIH_02375 2.6e-119 ybbM S transport system, permease component
HOIIOEIH_02376 9.8e-127 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HOIIOEIH_02377 4.2e-170 yjlA EG Putative multidrug resistance efflux transporter
HOIIOEIH_02378 2.9e-82 yjlB S Cupin domain
HOIIOEIH_02379 1.2e-65 yjlC S Protein of unknown function (DUF1641)
HOIIOEIH_02380 1.5e-217 yjlD 1.6.99.3 C NADH dehydrogenase
HOIIOEIH_02381 1.2e-274 uxaC 5.3.1.12 G glucuronate isomerase
HOIIOEIH_02382 6e-247 yjmB G symporter YjmB
HOIIOEIH_02383 1.7e-174 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HOIIOEIH_02384 2e-183 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HOIIOEIH_02385 6.2e-207 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HOIIOEIH_02386 6.4e-143 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_02387 7e-218 exuT G Sugar (and other) transporter
HOIIOEIH_02388 3.2e-181 exuR K transcriptional
HOIIOEIH_02389 4.9e-268 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HOIIOEIH_02390 6.4e-279 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HOIIOEIH_02391 1.6e-129 MA20_18170 S membrane transporter protein
HOIIOEIH_02392 2.2e-76 yjoA S DinB family
HOIIOEIH_02393 2.8e-243 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HOIIOEIH_02394 4.6e-213 S response regulator aspartate phosphatase
HOIIOEIH_02396 6e-36 S YCII-related domain
HOIIOEIH_02397 1.7e-160 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HOIIOEIH_02398 5.8e-59 yjqA S Bacterial PH domain
HOIIOEIH_02399 1.3e-100 yjqB S Pfam:DUF867
HOIIOEIH_02400 1.4e-153 ydbD P Catalase
HOIIOEIH_02401 3.4e-106 xkdA E IrrE N-terminal-like domain
HOIIOEIH_02402 4.6e-55 xre K Helix-turn-helix XRE-family like proteins
HOIIOEIH_02404 1.8e-137 xkdB K sequence-specific DNA binding
HOIIOEIH_02405 3.7e-111 xkdC L Bacterial dnaA protein
HOIIOEIH_02409 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HOIIOEIH_02410 2.7e-80 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HOIIOEIH_02411 8.8e-134 xtmA L phage terminase small subunit
HOIIOEIH_02412 3.3e-247 xtmB S phage terminase, large subunit
HOIIOEIH_02413 2e-280 yqbA S portal protein
HOIIOEIH_02414 1.2e-130 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HOIIOEIH_02415 2.9e-168 xkdG S Phage capsid family
HOIIOEIH_02416 1e-58 yqbG S Protein of unknown function (DUF3199)
HOIIOEIH_02417 6.2e-63 yqbH S Domain of unknown function (DUF3599)
HOIIOEIH_02418 3.3e-83 xkdI S Bacteriophage HK97-gp10, putative tail-component
HOIIOEIH_02419 1.6e-73 xkdJ
HOIIOEIH_02420 1.5e-253 xkdK S Phage tail sheath C-terminal domain
HOIIOEIH_02421 6.1e-76 xkdM S Phage tail tube protein
HOIIOEIH_02422 1.8e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
HOIIOEIH_02423 0.0 xkdO L Transglycosylase SLT domain
HOIIOEIH_02424 5.4e-121 xkdP S Lysin motif
HOIIOEIH_02425 8.4e-179 yqbQ 3.2.1.96 G NLP P60 protein
HOIIOEIH_02426 4.7e-39 xkdR S Protein of unknown function (DUF2577)
HOIIOEIH_02427 7.6e-68 xkdS S Protein of unknown function (DUF2634)
HOIIOEIH_02428 4.8e-188 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HOIIOEIH_02429 2.4e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HOIIOEIH_02430 2.1e-39
HOIIOEIH_02431 0.0
HOIIOEIH_02432 7.7e-44 xkdW S XkdW protein
HOIIOEIH_02433 2.1e-21 xkdX
HOIIOEIH_02434 1e-140 xepA
HOIIOEIH_02435 2.9e-36 xhlA S Haemolysin XhlA
HOIIOEIH_02436 1.1e-37 xhlB S SPP1 phage holin
HOIIOEIH_02437 1.6e-160 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HOIIOEIH_02438 1.9e-22 spoIISB S Stage II sporulation protein SB
HOIIOEIH_02439 3.1e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HOIIOEIH_02440 3.2e-173 pit P phosphate transporter
HOIIOEIH_02441 2e-109 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HOIIOEIH_02442 7.5e-231 steT E amino acid
HOIIOEIH_02443 4.2e-175 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HOIIOEIH_02445 1.9e-300 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOIIOEIH_02446 7.8e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HOIIOEIH_02448 3.2e-200 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HOIIOEIH_02449 1.5e-125 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HOIIOEIH_02450 4.8e-151 dppA E D-aminopeptidase
HOIIOEIH_02451 5.9e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOIIOEIH_02452 1.2e-172 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HOIIOEIH_02453 6.4e-182 dppD P Belongs to the ABC transporter superfamily
HOIIOEIH_02454 2e-310 dppE E ABC transporter substrate-binding protein
HOIIOEIH_02455 6.9e-170 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HOIIOEIH_02456 8.8e-193 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HOIIOEIH_02457 4.4e-158 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HOIIOEIH_02458 1.3e-182 ykfD E Belongs to the ABC transporter superfamily
HOIIOEIH_02459 1.3e-196 pgl 3.1.1.31 G 6-phosphogluconolactonase
HOIIOEIH_02460 3.5e-144 ykgA E Amidinotransferase
HOIIOEIH_02461 3.8e-91 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HOIIOEIH_02462 2.9e-213 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HOIIOEIH_02463 6.5e-13
HOIIOEIH_02464 6.2e-126 ykjA S Protein of unknown function (DUF421)
HOIIOEIH_02465 2.5e-89 ykkA S Protein of unknown function (DUF664)
HOIIOEIH_02466 1.6e-88 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HOIIOEIH_02467 9.4e-53 ykkC P Multidrug resistance protein
HOIIOEIH_02468 3.5e-49 ykkD P Multidrug resistance protein
HOIIOEIH_02469 5.8e-166 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HOIIOEIH_02470 1.4e-198 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOIIOEIH_02471 3.1e-218 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HOIIOEIH_02472 8.2e-70 ohrA O Organic hydroperoxide resistance protein
HOIIOEIH_02473 1.3e-70 ohrR K COG1846 Transcriptional regulators
HOIIOEIH_02474 2.1e-70 ohrB O Organic hydroperoxide resistance protein
HOIIOEIH_02475 4.3e-163 M Glycosyl transferase family 2
HOIIOEIH_02476 1.5e-77 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HOIIOEIH_02477 5.9e-101 5.4.2.11 G Belongs to the phosphoglycerate mutase family
HOIIOEIH_02478 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HOIIOEIH_02479 2.8e-174 isp O Belongs to the peptidase S8 family
HOIIOEIH_02480 3.5e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HOIIOEIH_02481 3.5e-132 ykoC P Cobalt transport protein
HOIIOEIH_02482 5.4e-287 P ABC transporter, ATP-binding protein
HOIIOEIH_02483 5.9e-90 ykoE S ABC-type cobalt transport system, permease component
HOIIOEIH_02484 2.9e-105 ykoF S YKOF-related Family
HOIIOEIH_02485 3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_02486 4.4e-234 ykoH 2.7.13.3 T Histidine kinase
HOIIOEIH_02487 5.6e-97 ykoI S Peptidase propeptide and YPEB domain
HOIIOEIH_02488 3.2e-76 ykoJ S Peptidase propeptide and YPEB domain
HOIIOEIH_02491 6.1e-220 mgtE P Acts as a magnesium transporter
HOIIOEIH_02492 4.2e-53 tnrA K transcriptional
HOIIOEIH_02493 3.5e-18
HOIIOEIH_02494 1.4e-23 ykoL
HOIIOEIH_02495 6.6e-81 mhqR K transcriptional
HOIIOEIH_02496 2.7e-194 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HOIIOEIH_02497 2.3e-93 ykoP G polysaccharide deacetylase
HOIIOEIH_02498 2.6e-149 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HOIIOEIH_02499 0.0 ykoS
HOIIOEIH_02500 3.8e-182 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HOIIOEIH_02501 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HOIIOEIH_02502 1.1e-156 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HOIIOEIH_02503 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HOIIOEIH_02504 3.3e-107 ykoX S membrane-associated protein
HOIIOEIH_02505 3.1e-173 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HOIIOEIH_02506 1.4e-128 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOIIOEIH_02507 2.8e-109 rsgI S Anti-sigma factor N-terminus
HOIIOEIH_02508 1.9e-26 sspD S small acid-soluble spore protein
HOIIOEIH_02509 9.8e-121 ykrK S Domain of unknown function (DUF1836)
HOIIOEIH_02510 1.2e-152 htpX O Belongs to the peptidase M48B family
HOIIOEIH_02511 9.1e-224 ktrB P COG0168 Trk-type K transport systems, membrane components
HOIIOEIH_02512 1.2e-10 ydfR S Protein of unknown function (DUF421)
HOIIOEIH_02513 5.3e-20 ykzE
HOIIOEIH_02514 8.2e-185 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HOIIOEIH_02515 0.0 kinE 2.7.13.3 T Histidine kinase
HOIIOEIH_02516 9.8e-83 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HOIIOEIH_02518 1.1e-192 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HOIIOEIH_02519 2.2e-221 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HOIIOEIH_02520 3.4e-129 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HOIIOEIH_02521 5e-226 mtnE 2.6.1.83 E Aminotransferase
HOIIOEIH_02522 2.5e-225 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HOIIOEIH_02523 2.6e-129 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HOIIOEIH_02524 1.7e-111 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HOIIOEIH_02525 2.3e-93 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HOIIOEIH_02526 3.3e-47 XK27_09985 S Protein of unknown function (DUF1232)
HOIIOEIH_02527 6.4e-09 S Spo0E like sporulation regulatory protein
HOIIOEIH_02528 2e-60 eag
HOIIOEIH_02529 2.1e-269 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HOIIOEIH_02530 1.3e-75 ykvE K transcriptional
HOIIOEIH_02531 1.5e-122 motB N Flagellar motor protein
HOIIOEIH_02532 1e-137 motA N flagellar motor
HOIIOEIH_02533 0.0 clpE O Belongs to the ClpA ClpB family
HOIIOEIH_02534 3.4e-178 ykvI S membrane
HOIIOEIH_02535 7.5e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HOIIOEIH_02536 1.4e-80 queD 4.1.2.50, 4.2.3.12 H synthase
HOIIOEIH_02537 9.2e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HOIIOEIH_02538 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HOIIOEIH_02539 2.5e-203 ykvP 3.5.1.28 M Glycosyl transferases group 1
HOIIOEIH_02540 8.6e-34 3.5.1.104 M LysM domain
HOIIOEIH_02541 8.7e-165 G Glycosyl hydrolases family 18
HOIIOEIH_02542 1.1e-41 ykvR S Protein of unknown function (DUF3219)
HOIIOEIH_02543 6e-25 ykvS S protein conserved in bacteria
HOIIOEIH_02544 2.7e-28
HOIIOEIH_02545 1.1e-94 ykvT 3.5.1.28 M Cell Wall Hydrolase
HOIIOEIH_02546 1.9e-234 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOIIOEIH_02547 4.9e-82 stoA CO thiol-disulfide
HOIIOEIH_02548 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HOIIOEIH_02549 3.8e-09
HOIIOEIH_02550 2.9e-204 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HOIIOEIH_02552 8.1e-166 ykvZ 5.1.1.1 K Transcriptional regulator
HOIIOEIH_02553 7.6e-128 glcT K antiterminator
HOIIOEIH_02554 0.0 ptsG 2.7.1.193, 2.7.1.199 G phosphotransferase system
HOIIOEIH_02555 2.1e-39 ptsH G phosphocarrier protein HPr
HOIIOEIH_02556 3.4e-300 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOIIOEIH_02557 7.2e-39 splA S Transcriptional regulator
HOIIOEIH_02558 5.9e-199 splB 4.1.99.14 L Spore photoproduct lyase
HOIIOEIH_02559 9.5e-121 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOIIOEIH_02560 1.1e-230 mcpC NT chemotaxis protein
HOIIOEIH_02561 8e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HOIIOEIH_02562 3.7e-113 ykwD J protein with SCP PR1 domains
HOIIOEIH_02563 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HOIIOEIH_02564 0.0 pilS 2.7.13.3 T Histidine kinase
HOIIOEIH_02565 1.6e-219 patA 2.6.1.1 E Aminotransferase
HOIIOEIH_02566 3.7e-15
HOIIOEIH_02567 7.6e-166 cheV 2.7.13.3 T Chemotaxis protein CheV
HOIIOEIH_02568 6.4e-84 ykyB S YkyB-like protein
HOIIOEIH_02569 3.4e-236 ykuC EGP Major facilitator Superfamily
HOIIOEIH_02570 1.6e-85 ykuD S protein conserved in bacteria
HOIIOEIH_02571 2.2e-159 ykuE S Metallophosphoesterase
HOIIOEIH_02572 3.2e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOIIOEIH_02573 6.3e-232 ykuI T Diguanylate phosphodiesterase
HOIIOEIH_02574 3.9e-37 ykuJ S protein conserved in bacteria
HOIIOEIH_02575 2.9e-93 ykuK S Ribonuclease H-like
HOIIOEIH_02576 3.9e-27 ykzF S Antirepressor AbbA
HOIIOEIH_02577 1.6e-76 ykuL S CBS domain
HOIIOEIH_02578 8.7e-167 ccpC K Transcriptional regulator
HOIIOEIH_02579 1.8e-81 fld C Flavodoxin domain
HOIIOEIH_02580 1.5e-166 ykuO
HOIIOEIH_02581 1.9e-72 fld C Flavodoxin
HOIIOEIH_02582 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HOIIOEIH_02583 6e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HOIIOEIH_02584 1.3e-35 ykuS S Belongs to the UPF0180 family
HOIIOEIH_02585 1.1e-136 ykuT M Mechanosensitive ion channel
HOIIOEIH_02587 2.5e-100 ykuU O Alkyl hydroperoxide reductase
HOIIOEIH_02588 1.7e-81 ykuV CO thiol-disulfide
HOIIOEIH_02589 1.5e-93 rok K Repressor of ComK
HOIIOEIH_02590 5.3e-133 yknT
HOIIOEIH_02591 1.4e-96 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HOIIOEIH_02592 2.8e-185 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HOIIOEIH_02593 1.2e-236 moeA 2.10.1.1 H molybdopterin
HOIIOEIH_02594 2.1e-86 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HOIIOEIH_02595 2.3e-81 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HOIIOEIH_02596 1.4e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HOIIOEIH_02597 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HOIIOEIH_02598 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HOIIOEIH_02599 7.5e-113 yknW S Yip1 domain
HOIIOEIH_02600 7.8e-152 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOIIOEIH_02601 1.6e-123 macB V ABC transporter, ATP-binding protein
HOIIOEIH_02602 1.7e-202 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HOIIOEIH_02603 2.2e-134 fruR K Transcriptional regulator
HOIIOEIH_02604 8.4e-165 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HOIIOEIH_02605 3.2e-307 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HOIIOEIH_02606 4.1e-104 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HOIIOEIH_02607 5.2e-38 ykoA
HOIIOEIH_02608 2.5e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HOIIOEIH_02609 3.6e-155 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HOIIOEIH_02610 6.8e-234 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HOIIOEIH_02611 1.1e-12 S Uncharacterized protein YkpC
HOIIOEIH_02612 2.5e-181 mreB D Rod-share determining protein MreBH
HOIIOEIH_02613 4.3e-43 abrB K of stationary sporulation gene expression
HOIIOEIH_02614 4e-235 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HOIIOEIH_02615 4e-145 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HOIIOEIH_02616 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HOIIOEIH_02617 1.2e-308 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HOIIOEIH_02618 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOIIOEIH_02619 1.4e-30 ykzG S Belongs to the UPF0356 family
HOIIOEIH_02620 6.3e-143 ykrA S hydrolases of the HAD superfamily
HOIIOEIH_02621 1.5e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOIIOEIH_02623 6.3e-98 recN L Putative cell-wall binding lipoprotein
HOIIOEIH_02624 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HOIIOEIH_02625 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HOIIOEIH_02626 2.4e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HOIIOEIH_02627 3.4e-245 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HOIIOEIH_02628 1e-60 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HOIIOEIH_02629 2.6e-272 speA 4.1.1.19 E Arginine
HOIIOEIH_02630 1.7e-41 yktA S Belongs to the UPF0223 family
HOIIOEIH_02631 8.7e-116 yktB S Belongs to the UPF0637 family
HOIIOEIH_02632 7.2e-26 ykzI
HOIIOEIH_02633 2.2e-145 suhB 3.1.3.25 G Inositol monophosphatase
HOIIOEIH_02634 9.6e-72 ykzC S Acetyltransferase (GNAT) family
HOIIOEIH_02635 1.9e-156 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HOIIOEIH_02636 4.3e-286 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HOIIOEIH_02637 3.3e-304 ylaA
HOIIOEIH_02638 1.4e-35 ylaB
HOIIOEIH_02639 1.3e-85 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HOIIOEIH_02640 6.3e-13 sigC S Putative zinc-finger
HOIIOEIH_02641 1.4e-33 ylaE
HOIIOEIH_02642 6.3e-22 S Family of unknown function (DUF5325)
HOIIOEIH_02643 0.0 typA T GTP-binding protein TypA
HOIIOEIH_02644 7.2e-47 ylaH S YlaH-like protein
HOIIOEIH_02645 2.1e-31 ylaI S protein conserved in bacteria
HOIIOEIH_02646 7e-86 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HOIIOEIH_02647 6.8e-248 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HOIIOEIH_02648 1.5e-80 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HOIIOEIH_02649 1.4e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
HOIIOEIH_02650 1.9e-43 ylaN S Belongs to the UPF0358 family
HOIIOEIH_02651 5.1e-210 ftsW D Belongs to the SEDS family
HOIIOEIH_02652 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HOIIOEIH_02653 8.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HOIIOEIH_02654 1.2e-163 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HOIIOEIH_02655 1.2e-186 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HOIIOEIH_02656 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HOIIOEIH_02657 1.6e-111 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HOIIOEIH_02658 2.3e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HOIIOEIH_02659 2.8e-160 ctaG S cytochrome c oxidase
HOIIOEIH_02660 1e-60 ylbA S YugN-like family
HOIIOEIH_02661 8.3e-73 ylbB T COG0517 FOG CBS domain
HOIIOEIH_02662 4e-195 ylbC S protein with SCP PR1 domains
HOIIOEIH_02663 6.1e-59 ylbD S Putative coat protein
HOIIOEIH_02664 1.5e-36 ylbE S YlbE-like protein
HOIIOEIH_02665 1.8e-75 ylbF S Belongs to the UPF0342 family
HOIIOEIH_02666 9.8e-39 ylbG S UPF0298 protein
HOIIOEIH_02667 4.6e-97 rsmD 2.1.1.171 L Methyltransferase
HOIIOEIH_02668 4.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOIIOEIH_02669 3.4e-217 ylbJ S Sporulation integral membrane protein YlbJ
HOIIOEIH_02670 1.6e-135 ylbK S esterase of the alpha-beta hydrolase superfamily
HOIIOEIH_02671 5.5e-181 ylbL T Belongs to the peptidase S16 family
HOIIOEIH_02672 1.3e-216 ylbM S Belongs to the UPF0348 family
HOIIOEIH_02673 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
HOIIOEIH_02674 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HOIIOEIH_02675 2.8e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HOIIOEIH_02676 1.4e-86 ylbP K n-acetyltransferase
HOIIOEIH_02677 1.6e-155 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HOIIOEIH_02678 2.1e-299 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HOIIOEIH_02679 2.9e-78 mraZ K Belongs to the MraZ family
HOIIOEIH_02680 5.8e-169 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HOIIOEIH_02681 2.9e-44 ftsL D Essential cell division protein
HOIIOEIH_02682 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HOIIOEIH_02683 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HOIIOEIH_02684 2e-272 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOIIOEIH_02685 4.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOIIOEIH_02686 8.2e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HOIIOEIH_02687 5.7e-186 spoVE D Belongs to the SEDS family
HOIIOEIH_02688 1.8e-198 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HOIIOEIH_02689 7.6e-166 murB 1.3.1.98 M cell wall formation
HOIIOEIH_02690 2.5e-136 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HOIIOEIH_02691 7e-103 ylxW S protein conserved in bacteria
HOIIOEIH_02692 1.2e-112 ylxX S protein conserved in bacteria
HOIIOEIH_02693 4.7e-58 sbp S small basic protein
HOIIOEIH_02694 6.6e-227 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HOIIOEIH_02695 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOIIOEIH_02696 0.0 bpr O COG1404 Subtilisin-like serine proteases
HOIIOEIH_02697 2.1e-166 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HOIIOEIH_02698 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOIIOEIH_02699 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOIIOEIH_02700 2.5e-144 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HOIIOEIH_02701 2.5e-239 argE 3.5.1.16 E Acetylornithine deacetylase
HOIIOEIH_02702 5.3e-37 ylmC S sporulation protein
HOIIOEIH_02703 2.6e-152 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HOIIOEIH_02704 4.3e-121 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HOIIOEIH_02705 3.3e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HOIIOEIH_02706 1.3e-39 yggT S membrane
HOIIOEIH_02707 2.8e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HOIIOEIH_02708 1.3e-66 divIVA D Cell division initiation protein
HOIIOEIH_02709 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HOIIOEIH_02710 2.1e-61 dksA T COG1734 DnaK suppressor protein
HOIIOEIH_02711 7e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HOIIOEIH_02712 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HOIIOEIH_02713 1.4e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HOIIOEIH_02714 1.1e-231 pyrP F Xanthine uracil
HOIIOEIH_02716 1.3e-160 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HOIIOEIH_02717 5.2e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HOIIOEIH_02718 1e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HOIIOEIH_02719 0.0 carB 6.3.5.5 F Belongs to the CarB family
HOIIOEIH_02720 3.2e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HOIIOEIH_02721 2.4e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HOIIOEIH_02722 2.5e-119 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HOIIOEIH_02723 1.7e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOIIOEIH_02724 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HOIIOEIH_02725 5e-177 cysP P phosphate transporter
HOIIOEIH_02726 2.8e-218 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HOIIOEIH_02727 6.8e-107 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HOIIOEIH_02728 2.6e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HOIIOEIH_02729 5.2e-139 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HOIIOEIH_02730 1.2e-72 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HOIIOEIH_02731 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HOIIOEIH_02732 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HOIIOEIH_02733 1.1e-150 yloC S stress-induced protein
HOIIOEIH_02734 1.5e-40 ylzA S Belongs to the UPF0296 family
HOIIOEIH_02735 1.2e-109 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HOIIOEIH_02736 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HOIIOEIH_02737 3.3e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HOIIOEIH_02738 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOIIOEIH_02739 1.4e-81 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOIIOEIH_02740 1.4e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOIIOEIH_02741 9.3e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HOIIOEIH_02742 1.6e-202 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HOIIOEIH_02743 3.1e-136 stp 3.1.3.16 T phosphatase
HOIIOEIH_02744 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HOIIOEIH_02745 2.8e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HOIIOEIH_02746 7.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HOIIOEIH_02747 4.8e-114 thiN 2.7.6.2 H thiamine pyrophosphokinase
HOIIOEIH_02748 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HOIIOEIH_02749 2.1e-58 asp S protein conserved in bacteria
HOIIOEIH_02750 1e-293 yloV S kinase related to dihydroxyacetone kinase
HOIIOEIH_02751 1.3e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HOIIOEIH_02752 5.1e-154 sdaAA 4.3.1.17 E L-serine dehydratase
HOIIOEIH_02753 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HOIIOEIH_02754 5.7e-79 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HOIIOEIH_02755 8.9e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HOIIOEIH_02756 5.2e-165 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HOIIOEIH_02757 3e-128 IQ reductase
HOIIOEIH_02758 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOIIOEIH_02759 2.6e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HOIIOEIH_02760 0.0 smc D Required for chromosome condensation and partitioning
HOIIOEIH_02761 8.3e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HOIIOEIH_02762 3.4e-80
HOIIOEIH_02763 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HOIIOEIH_02764 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOIIOEIH_02765 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HOIIOEIH_02766 1.3e-35 ylqC S Belongs to the UPF0109 family
HOIIOEIH_02767 3.1e-60 ylqD S YlqD protein
HOIIOEIH_02768 2.9e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOIIOEIH_02769 1.3e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HOIIOEIH_02770 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HOIIOEIH_02771 9.3e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HOIIOEIH_02772 7.4e-130 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOIIOEIH_02773 1e-256 ylqG
HOIIOEIH_02774 5.6e-43 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HOIIOEIH_02775 1.7e-210 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HOIIOEIH_02776 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HOIIOEIH_02777 5.5e-161 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HOIIOEIH_02778 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOIIOEIH_02779 3.4e-244 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HOIIOEIH_02780 2.4e-167 xerC L tyrosine recombinase XerC
HOIIOEIH_02781 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HOIIOEIH_02782 4.2e-240 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HOIIOEIH_02783 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HOIIOEIH_02784 6.3e-61 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HOIIOEIH_02785 9.9e-74 flgC N Belongs to the flagella basal body rod proteins family
HOIIOEIH_02786 2e-31 fliE N Flagellar hook-basal body
HOIIOEIH_02787 1.6e-243 fliF N The M ring may be actively involved in energy transduction
HOIIOEIH_02788 9.7e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HOIIOEIH_02789 7.6e-103 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HOIIOEIH_02790 1.7e-238 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HOIIOEIH_02791 3.6e-68 fliJ N Flagellar biosynthesis chaperone
HOIIOEIH_02792 6.1e-34 ylxF S MgtE intracellular N domain
HOIIOEIH_02793 1.1e-198 fliK N Flagellar hook-length control protein
HOIIOEIH_02794 4.6e-65 flgD N Flagellar basal body rod modification protein
HOIIOEIH_02795 2.9e-137 flgG N Flagellar basal body rod
HOIIOEIH_02796 3.5e-44 fliL N Controls the rotational direction of flagella during chemotaxis
HOIIOEIH_02797 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HOIIOEIH_02798 9.5e-158 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HOIIOEIH_02799 2.3e-57 cheB 3.1.1.61, 3.5.1.44 T response regulator
HOIIOEIH_02800 1.9e-94 fliZ N Flagellar biosynthesis protein, FliO
HOIIOEIH_02801 6.3e-109 fliP N Plays a role in the flagellum-specific transport system
HOIIOEIH_02802 3.2e-35 fliQ N Role in flagellar biosynthesis
HOIIOEIH_02803 1.1e-128 fliR N Flagellar biosynthetic protein FliR
HOIIOEIH_02804 3.4e-189 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HOIIOEIH_02805 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HOIIOEIH_02806 4.2e-187 flhF N Flagellar biosynthesis regulator FlhF
HOIIOEIH_02807 7.2e-153 flhG D Belongs to the ParA family
HOIIOEIH_02808 2e-189 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HOIIOEIH_02809 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HOIIOEIH_02810 1.2e-77 cheW NT COG0835 Chemotaxis signal transduction protein
HOIIOEIH_02811 3.7e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HOIIOEIH_02812 1.2e-85 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HOIIOEIH_02813 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOIIOEIH_02814 1.5e-59 ylxL
HOIIOEIH_02815 1.7e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HOIIOEIH_02816 7.7e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HOIIOEIH_02817 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HOIIOEIH_02818 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HOIIOEIH_02819 1.7e-142 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOIIOEIH_02820 1.4e-134 cdsA 2.7.7.41 S Belongs to the CDS family
HOIIOEIH_02821 2.1e-213 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HOIIOEIH_02822 2.9e-232 rasP M zinc metalloprotease
HOIIOEIH_02823 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HOIIOEIH_02824 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOIIOEIH_02825 1.3e-79 rimP S Required for maturation of 30S ribosomal subunits
HOIIOEIH_02826 4.3e-203 nusA K Participates in both transcription termination and antitermination
HOIIOEIH_02827 9.4e-35 ylxR K nucleic-acid-binding protein implicated in transcription termination
HOIIOEIH_02828 3.1e-47 ylxQ J ribosomal protein
HOIIOEIH_02829 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HOIIOEIH_02830 3e-44 ylxP S protein conserved in bacteria
HOIIOEIH_02831 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HOIIOEIH_02832 1.3e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HOIIOEIH_02833 7.7e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HOIIOEIH_02834 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HOIIOEIH_02835 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HOIIOEIH_02836 3.3e-175 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HOIIOEIH_02837 9.1e-231 pepR S Belongs to the peptidase M16 family
HOIIOEIH_02838 4.1e-40 ymxH S YlmC YmxH family
HOIIOEIH_02839 2.8e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HOIIOEIH_02840 6.3e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HOIIOEIH_02841 2.3e-190 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOIIOEIH_02842 1.4e-218 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HOIIOEIH_02843 1.3e-154 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOIIOEIH_02844 6.9e-306 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOIIOEIH_02845 3.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HOIIOEIH_02846 6.4e-31 S YlzJ-like protein
HOIIOEIH_02847 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HOIIOEIH_02848 9.2e-130 ymfC K Transcriptional regulator
HOIIOEIH_02849 8.8e-202 ymfD EGP Major facilitator Superfamily
HOIIOEIH_02850 7.3e-223 ymfF S Peptidase M16
HOIIOEIH_02851 2.8e-238 ymfH S zinc protease
HOIIOEIH_02852 2.2e-123 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HOIIOEIH_02853 1.4e-40 ymfJ S Protein of unknown function (DUF3243)
HOIIOEIH_02854 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HOIIOEIH_02855 3.7e-112 ymfM S protein conserved in bacteria
HOIIOEIH_02856 7.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOIIOEIH_02857 2.1e-230 cinA 3.5.1.42 S Belongs to the CinA family
HOIIOEIH_02858 7.6e-186 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOIIOEIH_02859 8.8e-199 pbpX V Beta-lactamase
HOIIOEIH_02860 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HOIIOEIH_02861 4.2e-152 ymdB S protein conserved in bacteria
HOIIOEIH_02862 1.2e-36 spoVS S Stage V sporulation protein S
HOIIOEIH_02863 5.1e-190 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HOIIOEIH_02864 9.4e-209 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HOIIOEIH_02865 4.2e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HOIIOEIH_02866 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HOIIOEIH_02867 9.4e-87 cotE S Spore coat protein
HOIIOEIH_02868 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HOIIOEIH_02869 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HOIIOEIH_02870 1.4e-59 S Regulatory protein YrvL
HOIIOEIH_02872 8.1e-94 ymcC S Membrane
HOIIOEIH_02873 6.7e-97 pksA K Transcriptional regulator
HOIIOEIH_02874 3.6e-120 pksB 3.1.2.6 S Polyketide biosynthesis
HOIIOEIH_02875 3.5e-152 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HOIIOEIH_02876 1.3e-166 pksD Q Acyl transferase domain
HOIIOEIH_02877 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HOIIOEIH_02878 2.2e-35 acpK IQ Phosphopantetheine attachment site
HOIIOEIH_02879 2.7e-222 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HOIIOEIH_02880 1e-237 pksG 2.3.3.10 I synthase
HOIIOEIH_02881 1e-134 pksH 4.2.1.18 I enoyl-CoA hydratase
HOIIOEIH_02882 1.1e-130 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HOIIOEIH_02883 0.0 rhiB IQ polyketide synthase
HOIIOEIH_02884 0.0 pfaA Q Polyketide synthase of type I
HOIIOEIH_02885 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HOIIOEIH_02886 0.0 dhbF IQ polyketide synthase
HOIIOEIH_02887 0.0 pks13 HQ Beta-ketoacyl synthase
HOIIOEIH_02888 2.8e-224 cypA C Cytochrome P450
HOIIOEIH_02889 1.1e-59 ymzB
HOIIOEIH_02890 4.3e-155 ymaE S Metallo-beta-lactamase superfamily
HOIIOEIH_02891 4.1e-245 aprX O Belongs to the peptidase S8 family
HOIIOEIH_02892 1.7e-08 K Transcriptional regulator
HOIIOEIH_02893 4.7e-123 ymaC S Replication protein
HOIIOEIH_02894 2.1e-76 ymaD O redox protein, regulator of disulfide bond formation
HOIIOEIH_02895 7.1e-51 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HOIIOEIH_02896 1.5e-47 ebrA P Small Multidrug Resistance protein
HOIIOEIH_02898 1.2e-38 ymaF S YmaF family
HOIIOEIH_02899 2.6e-169 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HOIIOEIH_02900 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HOIIOEIH_02901 3.3e-24
HOIIOEIH_02902 1.7e-21 ymzA
HOIIOEIH_02903 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HOIIOEIH_02904 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOIIOEIH_02905 1.1e-186 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOIIOEIH_02906 1e-105 ymaB
HOIIOEIH_02907 1.9e-109 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HOIIOEIH_02908 1.9e-175 spoVK O stage V sporulation protein K
HOIIOEIH_02909 2.4e-226 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HOIIOEIH_02910 1.8e-242 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HOIIOEIH_02911 1.1e-68 glnR K transcriptional
HOIIOEIH_02912 1.1e-258 glnA 6.3.1.2 E glutamine synthetase
HOIIOEIH_02913 2.6e-77 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HOIIOEIH_02914 8.5e-31
HOIIOEIH_02917 1e-246 xynT G MFS/sugar transport protein
HOIIOEIH_02918 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HOIIOEIH_02919 6.4e-210 xylR GK ROK family
HOIIOEIH_02920 3.1e-256 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HOIIOEIH_02921 1.6e-274 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HOIIOEIH_02922 3.7e-120 3.2.1.8 G Glycosyl hydrolases family 11
HOIIOEIH_02923 7.6e-97 yokF 3.1.31.1 L RNA catabolic process
HOIIOEIH_02924 3.9e-241 iolT EGP Major facilitator Superfamily
HOIIOEIH_02925 1.2e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOIIOEIH_02927 4e-70 yncE S Protein of unknown function (DUF2691)
HOIIOEIH_02928 3.3e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HOIIOEIH_02929 4e-15
HOIIOEIH_02932 1.3e-159 S Thymidylate synthase
HOIIOEIH_02934 3.8e-120 S Domain of unknown function, YrpD
HOIIOEIH_02937 2.3e-58
HOIIOEIH_02938 4.5e-71 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HOIIOEIH_02941 3e-178 chrA P chromate transporter, chromate ion transporter
HOIIOEIH_02943 3.6e-272 gerAA EG Spore germination protein
HOIIOEIH_02944 9.1e-182 gerAB U Spore germination
HOIIOEIH_02945 9.8e-193 gerLC S Spore germination protein
HOIIOEIH_02946 8.9e-134 yndG S DoxX-like family
HOIIOEIH_02947 1.2e-107 yndH S Domain of unknown function (DUF4166)
HOIIOEIH_02948 1.4e-279 yndJ S YndJ-like protein
HOIIOEIH_02950 2.3e-131 yndL S Replication protein
HOIIOEIH_02951 4.8e-68 yndM S Protein of unknown function (DUF2512)
HOIIOEIH_02952 3.3e-71 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HOIIOEIH_02953 1.2e-12
HOIIOEIH_02954 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HOIIOEIH_02955 1.9e-47 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HOIIOEIH_02956 3.4e-107 yneB L resolvase
HOIIOEIH_02957 3.1e-31 ynzC S UPF0291 protein
HOIIOEIH_02958 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HOIIOEIH_02959 4.5e-79 yneE S Sporulation inhibitor of replication protein sirA
HOIIOEIH_02960 1.8e-28 yneF S UPF0154 protein
HOIIOEIH_02961 1.2e-14 ynzD S Spo0E like sporulation regulatory protein
HOIIOEIH_02962 1.1e-124 ccdA O cytochrome c biogenesis protein
HOIIOEIH_02963 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HOIIOEIH_02964 1.6e-74 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HOIIOEIH_02965 4.1e-69 yneK S Protein of unknown function (DUF2621)
HOIIOEIH_02966 5e-63 hspX O Spore coat protein
HOIIOEIH_02967 3.9e-19 sspP S Belongs to the SspP family
HOIIOEIH_02968 4.2e-14 sspO S Belongs to the SspO family
HOIIOEIH_02969 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HOIIOEIH_02970 2e-86 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HOIIOEIH_02972 4e-08 sspN S Small acid-soluble spore protein N family
HOIIOEIH_02973 2.1e-33 tlp S Belongs to the Tlp family
HOIIOEIH_02974 2.7e-73 yneP S Thioesterase-like superfamily
HOIIOEIH_02975 1.3e-53 yneQ
HOIIOEIH_02976 2.9e-47 yneR S Belongs to the HesB IscA family
HOIIOEIH_02977 1.2e-92 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HOIIOEIH_02978 2e-65 yccU S CoA-binding protein
HOIIOEIH_02979 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOIIOEIH_02980 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOIIOEIH_02981 9.7e-11
HOIIOEIH_02982 1.5e-56 ynfC
HOIIOEIH_02983 1.6e-239 agcS E Sodium alanine symporter
HOIIOEIH_02984 1.9e-267 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HOIIOEIH_02986 1.1e-247 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HOIIOEIH_02987 7.3e-294 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HOIIOEIH_02988 1.1e-68 yngA S membrane
HOIIOEIH_02989 2.6e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HOIIOEIH_02990 5.5e-104 yngC S membrane-associated protein
HOIIOEIH_02991 1.2e-230 nrnB S phosphohydrolase (DHH superfamily)
HOIIOEIH_02992 2.7e-280 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HOIIOEIH_02993 3.6e-132 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HOIIOEIH_02994 3.4e-158 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HOIIOEIH_02995 3.3e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HOIIOEIH_02996 7.3e-242 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HOIIOEIH_02997 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HOIIOEIH_02998 7e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HOIIOEIH_02999 2.7e-12 S Family of unknown function (DUF5367)
HOIIOEIH_03000 1.5e-55 K Bacterial regulatory proteins, tetR family
HOIIOEIH_03001 2.3e-80 2.3.1.128 J Acetyltransferase (GNAT) domain
HOIIOEIH_03002 8e-293 yngK T Glycosyl hydrolase-like 10
HOIIOEIH_03003 1.5e-62 yngL S Protein of unknown function (DUF1360)
HOIIOEIH_03004 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOIIOEIH_03005 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOIIOEIH_03006 0.0 nrsA IQ polyketide synthase
HOIIOEIH_03007 3.4e-190 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HOIIOEIH_03008 4.4e-248 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HOIIOEIH_03009 7.6e-180 yoxA 5.1.3.3 G Aldose 1-epimerase
HOIIOEIH_03010 5.5e-240 yoeA V MATE efflux family protein
HOIIOEIH_03011 2.6e-97 yoeB S IseA DL-endopeptidase inhibitor
HOIIOEIH_03013 1.4e-95 L Integrase
HOIIOEIH_03014 4.8e-32 yoeD G Helix-turn-helix domain
HOIIOEIH_03015 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HOIIOEIH_03016 2e-139 gltR1 K Transcriptional regulator
HOIIOEIH_03017 2.7e-172 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HOIIOEIH_03018 4.7e-290 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HOIIOEIH_03019 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HOIIOEIH_03020 2.5e-153 gltC K Transcriptional regulator
HOIIOEIH_03021 6.6e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOIIOEIH_03022 2.4e-139 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOIIOEIH_03023 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HOIIOEIH_03024 1.5e-134 eryK 1.14.13.154 C Cytochrome P450
HOIIOEIH_03025 6.6e-43 L COG2963 Transposase and inactivated derivatives
HOIIOEIH_03026 1.5e-141 L Molecular Function DNA binding, Biological Process DNA recombination
HOIIOEIH_03027 1e-120 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_03028 3.6e-35 yoxC S Bacterial protein of unknown function (DUF948)
HOIIOEIH_03029 2.6e-119 yoxB
HOIIOEIH_03030 1.3e-85 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HOIIOEIH_03031 8.7e-131 V ABC-2 family transporter protein
HOIIOEIH_03032 6.2e-97 V ABC-2 family transporter protein
HOIIOEIH_03033 8.3e-90 V AAA domain, putative AbiEii toxin, Type IV TA system
HOIIOEIH_03034 1.9e-39 V AAA domain, putative AbiEii toxin, Type IV TA system
HOIIOEIH_03035 4.7e-78 hpr K helix_turn_helix multiple antibiotic resistance protein
HOIIOEIH_03036 2.2e-232 yoaB EGP Major facilitator Superfamily
HOIIOEIH_03037 5.7e-264 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HOIIOEIH_03038 2.5e-178 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOIIOEIH_03039 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HOIIOEIH_03040 3.1e-36 yoaF
HOIIOEIH_03043 1.6e-13
HOIIOEIH_03044 6.5e-42 S Protein of unknown function (DUF4025)
HOIIOEIH_03045 7.7e-164 mcpU NT methyl-accepting chemotaxis protein
HOIIOEIH_03046 2.5e-18 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HOIIOEIH_03047 2.9e-227 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HOIIOEIH_03048 2e-126 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HOIIOEIH_03049 8.4e-105 yoaK S Membrane
HOIIOEIH_03050 3e-190 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HOIIOEIH_03051 3.7e-129 IQ Enoyl-(Acyl carrier protein) reductase
HOIIOEIH_03052 1.5e-47 yoaW
HOIIOEIH_03053 7.5e-108 EGP Necrosis inducing protein (NPP1)
HOIIOEIH_03054 6.9e-119 yoqW S Belongs to the SOS response-associated peptidase family
HOIIOEIH_03057 1.3e-223 oxdC 4.1.1.2 G Oxalate decarboxylase
HOIIOEIH_03060 1.7e-60 yoaQ S Evidence 4 Homologs of previously reported genes of
HOIIOEIH_03062 2.9e-66
HOIIOEIH_03063 2.4e-159 yoaR V vancomycin resistance protein
HOIIOEIH_03064 2.8e-66 yoaS S Protein of unknown function (DUF2975)
HOIIOEIH_03065 4.4e-30 yozG K Transcriptional regulator
HOIIOEIH_03066 1.1e-133 yoaT S Protein of unknown function (DUF817)
HOIIOEIH_03067 2.5e-150 yoaU K LysR substrate binding domain
HOIIOEIH_03068 4.9e-154 yijE EG EamA-like transporter family
HOIIOEIH_03070 7.7e-13
HOIIOEIH_03071 2.9e-69 S CAAX protease self-immunity
HOIIOEIH_03072 1.9e-107 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HOIIOEIH_03073 7.7e-158 bla 3.5.2.6 V beta-lactamase
HOIIOEIH_03074 2.8e-11 G SMI1-KNR4 cell-wall
HOIIOEIH_03075 2.1e-114 AA10,CBM73 D Lytic polysaccharide mono-oxygenase, cellulose-degrading
HOIIOEIH_03076 3.2e-89 yrdA S DinB family
HOIIOEIH_03077 5.5e-92 ynaD J Acetyltransferase (GNAT) domain
HOIIOEIH_03078 3.2e-118 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HOIIOEIH_03079 4.5e-19 S aspartate phosphatase
HOIIOEIH_03080 1.7e-08 S aspartate phosphatase
HOIIOEIH_03081 2.8e-142 exoK GH16 M licheninase activity
HOIIOEIH_03082 2.4e-215 cypA C Cytochrome P450
HOIIOEIH_03083 2.7e-45 K Acetyltransferase (GNAT) family
HOIIOEIH_03084 9.4e-66 K Transcriptional regulator
HOIIOEIH_03085 2e-66 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HOIIOEIH_03086 4.6e-123 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HOIIOEIH_03087 1.1e-192 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOIIOEIH_03088 7.3e-09 ydcN K PFAM Cupin
HOIIOEIH_03089 8.4e-30 ansA 3.5.1.1 E PFAM L-asparaginase II
HOIIOEIH_03090 1.2e-161 scrR K transcriptional
HOIIOEIH_03091 4.5e-228 msmE G Bacterial extracellular solute-binding protein
HOIIOEIH_03092 8.7e-149 msmF P Binding-protein-dependent transport system inner membrane component
HOIIOEIH_03093 1.8e-140 msmG P PFAM binding-protein-dependent transport systems inner membrane component
HOIIOEIH_03094 8.8e-197 rafB P LacY proton/sugar symporter
HOIIOEIH_03095 5.9e-248 cscA 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HOIIOEIH_03096 3.3e-146 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
HOIIOEIH_03097 3e-72 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
HOIIOEIH_03100 1.5e-59
HOIIOEIH_03104 1.5e-91 3.1.21.1 L Protein of unknown function (DUF1524)
HOIIOEIH_03105 2.3e-29
HOIIOEIH_03106 5e-59 K Cupin domain
HOIIOEIH_03107 1.3e-72 ilvE 2.6.1.42 E Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HOIIOEIH_03108 8e-64 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOIIOEIH_03109 2.2e-125 C L-lactate permease
HOIIOEIH_03110 6.2e-213 S impB/mucB/samB family C-terminal domain
HOIIOEIH_03111 3.5e-52 S YolD-like protein
HOIIOEIH_03112 5e-46
HOIIOEIH_03114 4e-09 S Domain of unknown function (DUF4879)
HOIIOEIH_03115 1.8e-83 S SMI1-KNR4 cell-wall
HOIIOEIH_03116 3.6e-308 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HOIIOEIH_03117 2.3e-21 yokH G SMI1 / KNR4 family
HOIIOEIH_03118 1.6e-21 yokH G SMI1 / KNR4 family
HOIIOEIH_03119 6.9e-254 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HOIIOEIH_03120 1.3e-49 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HOIIOEIH_03121 2.4e-130 yobQ K helix_turn_helix, arabinose operon control protein
HOIIOEIH_03122 4.8e-118 yobR 2.3.1.1 J FR47-like protein
HOIIOEIH_03123 2.4e-88 yobS K Transcriptional regulator
HOIIOEIH_03124 5e-125 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HOIIOEIH_03125 9.9e-72 yobU K Bacterial transcription activator, effector binding domain
HOIIOEIH_03126 7.1e-159 yobV K WYL domain
HOIIOEIH_03127 5e-88 yobW
HOIIOEIH_03128 1.1e-50 czrA K transcriptional
HOIIOEIH_03129 2e-115 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HOIIOEIH_03130 9.6e-92 yozB S membrane
HOIIOEIH_03131 8.6e-134
HOIIOEIH_03132 1.2e-91 yocC
HOIIOEIH_03133 1.9e-178 yocD 3.4.17.13 V peptidase S66
HOIIOEIH_03135 9.7e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HOIIOEIH_03136 3.6e-186 desK 2.7.13.3 T Histidine kinase
HOIIOEIH_03137 1.3e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOIIOEIH_03138 3.4e-230 yidK S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOIIOEIH_03139 1.1e-108 yocH CBM50 M COG1388 FOG LysM repeat
HOIIOEIH_03140 0.0 recQ 3.6.4.12 L DNA helicase
HOIIOEIH_03141 9.7e-112 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HOIIOEIH_03142 1.5e-78 dksA T general stress protein
HOIIOEIH_03143 4.2e-56 yozO S Bacterial PH domain
HOIIOEIH_03144 1.8e-30 yozC
HOIIOEIH_03145 8.3e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HOIIOEIH_03146 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HOIIOEIH_03147 4.7e-162 sodA 1.15.1.1 P Superoxide dismutase
HOIIOEIH_03148 1.9e-226 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HOIIOEIH_03149 2.7e-161 yocS S -transporter
HOIIOEIH_03150 1.1e-186 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HOIIOEIH_03151 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HOIIOEIH_03152 0.0 yojO P Von Willebrand factor
HOIIOEIH_03153 2.7e-160 yojN S ATPase family associated with various cellular activities (AAA)
HOIIOEIH_03154 2.7e-103 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HOIIOEIH_03155 2.4e-183 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HOIIOEIH_03156 9.1e-215 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HOIIOEIH_03157 3.2e-107 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HOIIOEIH_03159 4e-235 norM V Multidrug efflux pump
HOIIOEIH_03160 6.3e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HOIIOEIH_03161 6.2e-125 yojG S deacetylase
HOIIOEIH_03162 8.2e-60 yojF S Protein of unknown function (DUF1806)
HOIIOEIH_03163 3.1e-41
HOIIOEIH_03164 6.8e-159 rarD S -transporter
HOIIOEIH_03165 7.8e-66 yozR S COG0071 Molecular chaperone (small heat shock protein)
HOIIOEIH_03166 1.5e-09
HOIIOEIH_03167 3e-195 gntP EG COG2610 H gluconate symporter and related permeases
HOIIOEIH_03168 3.7e-61 yodA S tautomerase
HOIIOEIH_03169 4.4e-55 yodB K transcriptional
HOIIOEIH_03170 9.1e-107 yodC C nitroreductase
HOIIOEIH_03171 6.3e-108 mhqD S Carboxylesterase
HOIIOEIH_03172 4.9e-165 yodE E COG0346 Lactoylglutathione lyase and related lyases
HOIIOEIH_03173 3.1e-27 S Protein of unknown function (DUF3311)
HOIIOEIH_03174 4e-265 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOIIOEIH_03175 4.4e-245 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HOIIOEIH_03176 3.4e-121 yodH Q Methyltransferase
HOIIOEIH_03177 6.4e-22 yodI
HOIIOEIH_03178 2e-136 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HOIIOEIH_03179 1.6e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HOIIOEIH_03180 1e-07
HOIIOEIH_03181 1.4e-53 yodL S YodL-like
HOIIOEIH_03182 1.5e-101 yodM 3.6.1.27 I Acid phosphatase homologues
HOIIOEIH_03183 2.8e-24 yozD S YozD-like protein
HOIIOEIH_03185 3.5e-123 yodN
HOIIOEIH_03186 6.9e-36 yozE S Belongs to the UPF0346 family
HOIIOEIH_03187 2.3e-44 yokU S YokU-like protein, putative antitoxin
HOIIOEIH_03188 3.2e-272 kamA 5.4.3.2 E lysine 2,3-aminomutase
HOIIOEIH_03189 1.3e-140 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HOIIOEIH_03190 4.9e-251 yodQ 3.5.1.16 E Acetylornithine deacetylase
HOIIOEIH_03191 6.6e-111 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HOIIOEIH_03192 1.6e-120 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HOIIOEIH_03193 8.7e-235 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOIIOEIH_03194 2.9e-137 yiiD K acetyltransferase
HOIIOEIH_03195 1.7e-232 cgeD M maturation of the outermost layer of the spore
HOIIOEIH_03196 9.8e-33 cgeC
HOIIOEIH_03197 1.4e-55 cgeA
HOIIOEIH_03198 5.5e-167 cgeB S Spore maturation protein
HOIIOEIH_03199 1.3e-194 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HOIIOEIH_03200 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
HOIIOEIH_03201 8.6e-75 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HOIIOEIH_03202 3.9e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOIIOEIH_03203 1.8e-69 ypoP K transcriptional
HOIIOEIH_03204 3.3e-218 mepA V MATE efflux family protein
HOIIOEIH_03205 7.1e-29 ypmT S Uncharacterized ympT
HOIIOEIH_03206 1.4e-96 ypmS S protein conserved in bacteria
HOIIOEIH_03207 1.9e-133 ypmR E GDSL-like Lipase/Acylhydrolase
HOIIOEIH_03208 9e-104 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HOIIOEIH_03209 2e-39 ypmP S Protein of unknown function (DUF2535)
HOIIOEIH_03210 2.6e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HOIIOEIH_03211 1.1e-162 pspF K Transcriptional regulator
HOIIOEIH_03212 1.1e-107 hlyIII S protein, Hemolysin III
HOIIOEIH_03213 1.6e-106 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HOIIOEIH_03214 7.9e-88 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HOIIOEIH_03215 1.4e-152 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOIIOEIH_03216 1.6e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HOIIOEIH_03217 8.9e-110 ypjP S YpjP-like protein
HOIIOEIH_03218 9.9e-138 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HOIIOEIH_03219 6.6e-75 yphP S Belongs to the UPF0403 family
HOIIOEIH_03220 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HOIIOEIH_03221 1.9e-153 ypgR C COG0694 Thioredoxin-like proteins and domains
HOIIOEIH_03222 6.9e-102 ypgQ S phosphohydrolase
HOIIOEIH_03223 3.9e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HOIIOEIH_03224 2.2e-173 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HOIIOEIH_03225 6.8e-212 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HOIIOEIH_03226 1e-30 cspD K Cold-shock protein
HOIIOEIH_03227 1e-16 degR
HOIIOEIH_03228 5.6e-32 S Protein of unknown function (DUF2564)
HOIIOEIH_03229 1.9e-28 ypeQ S Zinc-finger
HOIIOEIH_03230 8.6e-122 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HOIIOEIH_03231 6.9e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HOIIOEIH_03232 8.8e-62 rnhA 3.1.26.4 L Ribonuclease
HOIIOEIH_03234 1.1e-164 polA 2.7.7.7 L 5'3' exonuclease
HOIIOEIH_03235 2e-07
HOIIOEIH_03236 7.2e-37 ypbS S Protein of unknown function (DUF2533)
HOIIOEIH_03237 0.0 ypbR S Dynamin family
HOIIOEIH_03238 4.6e-80 ypbQ S protein conserved in bacteria
HOIIOEIH_03239 7.7e-197 bcsA Q Naringenin-chalcone synthase
HOIIOEIH_03240 9.5e-218 pbuX F xanthine
HOIIOEIH_03241 6.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HOIIOEIH_03242 1.5e-288 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HOIIOEIH_03243 4.7e-169 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HOIIOEIH_03244 7.5e-98 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HOIIOEIH_03245 6.7e-176 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HOIIOEIH_03246 8.8e-179 ptxS K transcriptional
HOIIOEIH_03247 1e-156 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HOIIOEIH_03248 2.1e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOIIOEIH_03249 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HOIIOEIH_03251 8.7e-22 S YpzG-like protein
HOIIOEIH_03252 1.6e-47 yqgA
HOIIOEIH_03253 1e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HOIIOEIH_03254 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HOIIOEIH_03255 6.1e-94 ypsA S Belongs to the UPF0398 family
HOIIOEIH_03256 4.3e-220 yprB L RNase_H superfamily
HOIIOEIH_03257 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HOIIOEIH_03258 2.5e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HOIIOEIH_03259 5.4e-66 hspX O Belongs to the small heat shock protein (HSP20) family
HOIIOEIH_03260 2.6e-19 yppG S YppG-like protein
HOIIOEIH_03261 3.3e-07 S YppF-like protein
HOIIOEIH_03262 1.3e-10 yppE S Bacterial domain of unknown function (DUF1798)
HOIIOEIH_03265 1.8e-178 yppC S Protein of unknown function (DUF2515)
HOIIOEIH_03266 1.1e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HOIIOEIH_03267 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HOIIOEIH_03268 4e-84 ypoC
HOIIOEIH_03269 1.2e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HOIIOEIH_03270 2.4e-127 dnaD L DNA replication protein DnaD
HOIIOEIH_03271 4.2e-250 asnS 6.1.1.22 J asparaginyl-tRNA
HOIIOEIH_03272 3.8e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HOIIOEIH_03273 4.2e-78 ypmB S protein conserved in bacteria
HOIIOEIH_03274 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HOIIOEIH_03275 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HOIIOEIH_03276 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HOIIOEIH_03277 6.5e-151 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HOIIOEIH_03278 1.6e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HOIIOEIH_03279 1.3e-179 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HOIIOEIH_03280 1.7e-202 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HOIIOEIH_03281 5.1e-204 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HOIIOEIH_03282 2.1e-126 bshB1 S proteins, LmbE homologs
HOIIOEIH_03283 4.7e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HOIIOEIH_03284 4.2e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HOIIOEIH_03285 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HOIIOEIH_03286 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HOIIOEIH_03287 7.7e-138 ypjB S sporulation protein
HOIIOEIH_03288 1.5e-95 ypjA S membrane
HOIIOEIH_03289 3.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HOIIOEIH_03290 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HOIIOEIH_03291 1e-95 qcrA C Menaquinol-cytochrome c reductase
HOIIOEIH_03292 7e-72 ypiF S Protein of unknown function (DUF2487)
HOIIOEIH_03293 2.8e-99 ypiB S Belongs to the UPF0302 family
HOIIOEIH_03294 1.2e-228 S COG0457 FOG TPR repeat
HOIIOEIH_03295 4.2e-226 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HOIIOEIH_03296 3.2e-198 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HOIIOEIH_03297 1.4e-198 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOIIOEIH_03298 3.6e-135 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HOIIOEIH_03299 3.6e-224 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HOIIOEIH_03300 1.2e-104 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HOIIOEIH_03301 3.2e-117 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HOIIOEIH_03302 2.3e-155 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOIIOEIH_03303 9.6e-278 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOIIOEIH_03304 1.6e-61 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HOIIOEIH_03305 5.1e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HOIIOEIH_03306 3.6e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HOIIOEIH_03307 1.8e-139 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HOIIOEIH_03309 7.7e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HOIIOEIH_03310 2.2e-193 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HOIIOEIH_03311 1.7e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HOIIOEIH_03312 6.9e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HOIIOEIH_03313 3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HOIIOEIH_03314 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HOIIOEIH_03315 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HOIIOEIH_03316 3.2e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HOIIOEIH_03317 7.5e-132 yphF
HOIIOEIH_03318 2.7e-18 yphE S Protein of unknown function (DUF2768)
HOIIOEIH_03319 5.9e-175 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HOIIOEIH_03320 1.7e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HOIIOEIH_03321 4.6e-28 ypzH
HOIIOEIH_03322 1.8e-159 seaA S YIEGIA protein
HOIIOEIH_03323 1.7e-97 yphA
HOIIOEIH_03324 1e-07 S YpzI-like protein
HOIIOEIH_03325 6.5e-177 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HOIIOEIH_03326 6.2e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HOIIOEIH_03327 4.4e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HOIIOEIH_03328 9.1e-23 S Family of unknown function (DUF5359)
HOIIOEIH_03329 1.9e-97 ypfA M Flagellar protein YcgR
HOIIOEIH_03330 2.8e-249 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HOIIOEIH_03331 6.7e-154 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HOIIOEIH_03332 1.1e-116 prsW S Involved in the degradation of specific anti-sigma factors
HOIIOEIH_03333 9.9e-172 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HOIIOEIH_03334 4.4e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HOIIOEIH_03335 5.3e-96 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HOIIOEIH_03336 1.6e-140 ypbG S Calcineurin-like phosphoesterase superfamily domain
HOIIOEIH_03337 4.6e-73 ypbF S Protein of unknown function (DUF2663)
HOIIOEIH_03338 1.7e-65 ypbE M Lysin motif
HOIIOEIH_03339 5.2e-94 ypbD S metal-dependent membrane protease
HOIIOEIH_03340 3.3e-275 recQ 3.6.4.12 L DNA helicase
HOIIOEIH_03341 4.6e-186 ypbB 5.1.3.1 S protein conserved in bacteria
HOIIOEIH_03342 4.7e-41 fer C Ferredoxin
HOIIOEIH_03343 1.2e-81 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HOIIOEIH_03344 6.4e-10
HOIIOEIH_03345 3.5e-291 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOIIOEIH_03346 1.3e-129 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HOIIOEIH_03347 1.7e-183 rsiX
HOIIOEIH_03348 8.5e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HOIIOEIH_03349 0.0 resE 2.7.13.3 T Histidine kinase
HOIIOEIH_03350 8.3e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_03351 7e-212 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HOIIOEIH_03352 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HOIIOEIH_03353 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HOIIOEIH_03354 4.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HOIIOEIH_03355 7.1e-87 spmB S Spore maturation protein
HOIIOEIH_03356 7.8e-103 spmA S Spore maturation protein
HOIIOEIH_03357 1.2e-205 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HOIIOEIH_03358 1.9e-95 ypuI S Protein of unknown function (DUF3907)
HOIIOEIH_03359 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HOIIOEIH_03360 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HOIIOEIH_03361 1.7e-85 ypuF S Domain of unknown function (DUF309)
HOIIOEIH_03362 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOIIOEIH_03363 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HOIIOEIH_03364 6e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HOIIOEIH_03365 4.5e-112 ribE 2.5.1.9 H Riboflavin synthase
HOIIOEIH_03366 3e-193 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HOIIOEIH_03367 3.3e-53 ypuD
HOIIOEIH_03368 7.8e-97 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HOIIOEIH_03369 4.6e-13
HOIIOEIH_03370 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HOIIOEIH_03372 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOIIOEIH_03374 5.8e-147 ypuA S Secreted protein
HOIIOEIH_03375 1.3e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HOIIOEIH_03376 3e-260 spoVAF EG Stage V sporulation protein AF
HOIIOEIH_03377 4.2e-107 spoVAEA S stage V sporulation protein
HOIIOEIH_03378 3.8e-57 spoVAEB S stage V sporulation protein
HOIIOEIH_03379 1.6e-188 spoVAD I Stage V sporulation protein AD
HOIIOEIH_03380 5.1e-78 spoVAC S stage V sporulation protein AC
HOIIOEIH_03381 3.8e-67 spoVAB S Stage V sporulation protein AB
HOIIOEIH_03382 1.8e-110 spoVAA S Stage V sporulation protein AA
HOIIOEIH_03383 2.2e-134 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOIIOEIH_03384 1.1e-74 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HOIIOEIH_03385 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HOIIOEIH_03386 2.1e-208 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HOIIOEIH_03387 3.2e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HOIIOEIH_03388 9.1e-228 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HOIIOEIH_03389 4.4e-166 xerD L recombinase XerD
HOIIOEIH_03390 1.1e-36 S Protein of unknown function (DUF4227)
HOIIOEIH_03391 2.4e-80 fur P Belongs to the Fur family
HOIIOEIH_03392 5.1e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HOIIOEIH_03393 3.3e-27 yqkK
HOIIOEIH_03394 7.5e-239 mleA 1.1.1.38 C malic enzyme
HOIIOEIH_03395 1.9e-200 mleN C Na H antiporter
HOIIOEIH_03396 7e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HOIIOEIH_03397 6.1e-185 ansA 3.5.1.1 EJ L-asparaginase
HOIIOEIH_03398 4.2e-56 ansR K Transcriptional regulator
HOIIOEIH_03399 3.2e-209 yqxK 3.6.4.12 L DNA helicase
HOIIOEIH_03400 9.9e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HOIIOEIH_03402 2.4e-159 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HOIIOEIH_03403 2.9e-10 yqkE S Protein of unknown function (DUF3886)
HOIIOEIH_03404 1.5e-156 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HOIIOEIH_03405 3.3e-182 ftsW D Belongs to the SEDS family
HOIIOEIH_03406 1.8e-191 rodA D Belongs to the SEDS family
HOIIOEIH_03407 1.6e-93 K Protein of unknown function (DUF1232)
HOIIOEIH_03408 1.2e-38 yqkC S Protein of unknown function (DUF2552)
HOIIOEIH_03409 2.8e-54 yqkB S Belongs to the HesB IscA family
HOIIOEIH_03410 6.4e-177 yqkA K GrpB protein
HOIIOEIH_03411 2.7e-52 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HOIIOEIH_03412 2.6e-85 yqjY K acetyltransferase
HOIIOEIH_03413 1.2e-50 S YolD-like protein
HOIIOEIH_03414 1.9e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOIIOEIH_03416 1.1e-215 yqjV G Major Facilitator Superfamily
HOIIOEIH_03418 1.5e-67 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOIIOEIH_03419 3.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HOIIOEIH_03420 3.9e-235 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HOIIOEIH_03421 3.6e-140 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_03422 9.5e-167 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HOIIOEIH_03423 2.1e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOIIOEIH_03424 2.2e-301 rocB E arginine degradation protein
HOIIOEIH_03425 2.2e-190 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HOIIOEIH_03426 3.6e-137 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HOIIOEIH_03427 1.4e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HOIIOEIH_03428 4.8e-168 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HOIIOEIH_03429 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HOIIOEIH_03430 2.6e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOIIOEIH_03431 1.6e-227 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOIIOEIH_03432 2.1e-24 yqzJ
HOIIOEIH_03433 2.1e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOIIOEIH_03434 7.8e-129 yqjF S Uncharacterized conserved protein (COG2071)
HOIIOEIH_03435 1.8e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HOIIOEIH_03436 8e-277 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HOIIOEIH_03437 1.9e-66 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HOIIOEIH_03439 1.8e-95 yqjB S protein conserved in bacteria
HOIIOEIH_03440 2.9e-171 yqjA S Putative aromatic acid exporter C-terminal domain
HOIIOEIH_03441 6.8e-125 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HOIIOEIH_03442 1.6e-104 artQ E COG0765 ABC-type amino acid transport system, permease component
HOIIOEIH_03443 5e-134 artP ET Belongs to the bacterial solute-binding protein 3 family
HOIIOEIH_03444 9.3e-77 yqiW S Belongs to the UPF0403 family
HOIIOEIH_03445 1.4e-153 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HOIIOEIH_03446 1.4e-201 norA EGP Major facilitator Superfamily
HOIIOEIH_03447 5.6e-147 bmrR K helix_turn_helix, mercury resistance
HOIIOEIH_03448 3.3e-207 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HOIIOEIH_03449 4.3e-183 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HOIIOEIH_03450 5.2e-184 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HOIIOEIH_03451 1.4e-262 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HOIIOEIH_03452 1e-196 buk 2.7.2.7 C Belongs to the acetokinase family
HOIIOEIH_03453 4.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HOIIOEIH_03454 2e-150 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HOIIOEIH_03455 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HOIIOEIH_03456 6.4e-32 yqzF S Protein of unknown function (DUF2627)
HOIIOEIH_03457 9.3e-156 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HOIIOEIH_03458 1.1e-267 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HOIIOEIH_03459 3.1e-201 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HOIIOEIH_03460 3.6e-205 mmgC I acyl-CoA dehydrogenase
HOIIOEIH_03461 2.9e-146 hbdA 1.1.1.157 I Dehydrogenase
HOIIOEIH_03462 3.4e-206 mmgA 2.3.1.9 I Belongs to the thiolase family
HOIIOEIH_03463 4.3e-119 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HOIIOEIH_03464 5.6e-104 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HOIIOEIH_03465 1e-26
HOIIOEIH_03466 8.3e-210 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HOIIOEIH_03469 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HOIIOEIH_03470 2.4e-234 rseP 3.4.21.116 M Stage IV sporulation protein B
HOIIOEIH_03471 4.2e-290 recN L May be involved in recombinational repair of damaged DNA
HOIIOEIH_03472 1.1e-77 argR K Regulates arginine biosynthesis genes
HOIIOEIH_03473 4.8e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HOIIOEIH_03474 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOIIOEIH_03475 1.9e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HOIIOEIH_03476 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOIIOEIH_03477 5.7e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOIIOEIH_03478 3.3e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HOIIOEIH_03479 9.6e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOIIOEIH_03480 2.4e-66 yqhY S protein conserved in bacteria
HOIIOEIH_03481 1e-254 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HOIIOEIH_03482 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HOIIOEIH_03483 7.8e-88 spoIIIAH S SpoIIIAH-like protein
HOIIOEIH_03484 6.5e-109 spoIIIAG S stage III sporulation protein AG
HOIIOEIH_03485 7.2e-99 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HOIIOEIH_03486 4.6e-195 spoIIIAE S stage III sporulation protein AE
HOIIOEIH_03487 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HOIIOEIH_03488 7.6e-29 spoIIIAC S stage III sporulation protein AC
HOIIOEIH_03489 6e-83 spoIIIAB S Stage III sporulation protein
HOIIOEIH_03490 3.6e-163 spoIIIAA S stage III sporulation protein AA
HOIIOEIH_03491 1e-36 yqhV S Protein of unknown function (DUF2619)
HOIIOEIH_03492 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOIIOEIH_03493 8.6e-169 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HOIIOEIH_03494 1e-75 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HOIIOEIH_03495 1.9e-87 yqhR S Conserved membrane protein YqhR
HOIIOEIH_03496 5.4e-170 yqhQ S Protein of unknown function (DUF1385)
HOIIOEIH_03497 3.2e-60 yqhP
HOIIOEIH_03498 1.3e-162 yqhO S esterase of the alpha-beta hydrolase superfamily
HOIIOEIH_03499 3.6e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HOIIOEIH_03500 9.8e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HOIIOEIH_03501 1.1e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
HOIIOEIH_03502 3.9e-281 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HOIIOEIH_03503 7.6e-247 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HOIIOEIH_03504 2e-189 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HOIIOEIH_03505 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HOIIOEIH_03506 5.3e-147 yqhG S Bacterial protein YqhG of unknown function
HOIIOEIH_03507 1.1e-23 sinI S Anti-repressor SinI
HOIIOEIH_03508 1e-54 sinR K transcriptional
HOIIOEIH_03509 3.4e-138 tasA S Cell division protein FtsN
HOIIOEIH_03510 9e-56 sipW 3.4.21.89 U Signal peptidase
HOIIOEIH_03511 2.6e-95 yqxM
HOIIOEIH_03512 7.7e-52 yqzG S Protein of unknown function (DUF3889)
HOIIOEIH_03513 1.2e-25 yqzE S YqzE-like protein
HOIIOEIH_03514 5.9e-48 S ComG operon protein 7
HOIIOEIH_03515 4.1e-54 comGF U Putative Competence protein ComGF
HOIIOEIH_03516 1.7e-49 comGE
HOIIOEIH_03517 2.8e-63 gspH NU protein transport across the cell outer membrane
HOIIOEIH_03518 6.8e-47 comGC U Required for transformation and DNA binding
HOIIOEIH_03519 2.5e-165 comGB NU COG1459 Type II secretory pathway, component PulF
HOIIOEIH_03520 3.4e-197 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HOIIOEIH_03521 1.3e-48 ylbB S Cbs domain
HOIIOEIH_03522 3.9e-165 corA P Mg2 transporter protein
HOIIOEIH_03523 1e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HOIIOEIH_03524 6e-133 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HOIIOEIH_03526 2.1e-61 yqgZ 1.20.4.1 P Belongs to the ArsC family
HOIIOEIH_03527 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HOIIOEIH_03528 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HOIIOEIH_03529 4.4e-22 yqgW S Protein of unknown function (DUF2759)
HOIIOEIH_03530 1.3e-48 yqgV S Thiamine-binding protein
HOIIOEIH_03531 1e-177 yqgU
HOIIOEIH_03532 1.4e-209 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HOIIOEIH_03533 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HOIIOEIH_03534 5.9e-178 glcK 2.7.1.2 G Glucokinase
HOIIOEIH_03535 6.6e-247 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HOIIOEIH_03536 4.3e-09 yqgO
HOIIOEIH_03537 3.1e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HOIIOEIH_03538 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HOIIOEIH_03539 7.9e-170 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HOIIOEIH_03541 1e-49 yqzD
HOIIOEIH_03542 1.5e-72 yqzC S YceG-like family
HOIIOEIH_03543 2.3e-142 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOIIOEIH_03544 1.8e-142 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOIIOEIH_03545 1.1e-156 pstA P Phosphate transport system permease
HOIIOEIH_03546 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HOIIOEIH_03547 3.2e-148 pstS P Phosphate
HOIIOEIH_03548 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HOIIOEIH_03549 1.8e-216 yqgE EGP Major facilitator superfamily
HOIIOEIH_03550 7e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HOIIOEIH_03551 7.6e-72 yqgC S protein conserved in bacteria
HOIIOEIH_03552 3.1e-128 yqgB S Protein of unknown function (DUF1189)
HOIIOEIH_03553 7.6e-46 yqfZ M LysM domain
HOIIOEIH_03554 2.4e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HOIIOEIH_03555 1.3e-55 yqfX S membrane
HOIIOEIH_03556 7.9e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HOIIOEIH_03557 1.6e-76 zur P Belongs to the Fur family
HOIIOEIH_03558 4.6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HOIIOEIH_03559 2.5e-34 yqfT S Protein of unknown function (DUF2624)
HOIIOEIH_03560 4.8e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HOIIOEIH_03561 2.6e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HOIIOEIH_03562 3.2e-26 yqfQ S YqfQ-like protein
HOIIOEIH_03563 2.1e-174 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HOIIOEIH_03564 3.5e-205 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HOIIOEIH_03565 5e-111 trmK 2.1.1.217 S SAM-dependent methyltransferase
HOIIOEIH_03566 3.8e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
HOIIOEIH_03567 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HOIIOEIH_03568 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HOIIOEIH_03569 5.5e-86 yaiI S Belongs to the UPF0178 family
HOIIOEIH_03570 7.6e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HOIIOEIH_03571 4.4e-112 ccpN K CBS domain
HOIIOEIH_03572 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HOIIOEIH_03573 1.1e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HOIIOEIH_03574 1.9e-141 recO L Involved in DNA repair and RecF pathway recombination
HOIIOEIH_03575 8.4e-19 S YqzL-like protein
HOIIOEIH_03576 3.4e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOIIOEIH_03577 1.6e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HOIIOEIH_03578 3.7e-58 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HOIIOEIH_03579 3.7e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOIIOEIH_03580 0.0 yqfF S membrane-associated HD superfamily hydrolase
HOIIOEIH_03582 3.4e-172 phoH T Phosphate starvation-inducible protein PhoH
HOIIOEIH_03583 2.4e-199 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HOIIOEIH_03584 2.7e-45 yqfC S sporulation protein YqfC
HOIIOEIH_03585 7.4e-23 yqfB
HOIIOEIH_03586 2.5e-114 yqfA S UPF0365 protein
HOIIOEIH_03587 4.7e-217 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HOIIOEIH_03588 1.1e-64 yqeY S Yqey-like protein
HOIIOEIH_03589 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HOIIOEIH_03590 4.7e-155 yqeW P COG1283 Na phosphate symporter
HOIIOEIH_03591 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HOIIOEIH_03592 7.7e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HOIIOEIH_03593 1e-173 prmA J Methylates ribosomal protein L11
HOIIOEIH_03594 1.5e-179 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HOIIOEIH_03595 0.0 dnaK O Heat shock 70 kDa protein
HOIIOEIH_03596 9.4e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOIIOEIH_03597 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HOIIOEIH_03598 5.9e-208 hemN H Involved in the biosynthesis of porphyrin-containing compound
HOIIOEIH_03599 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HOIIOEIH_03600 3e-51 yqxA S Protein of unknown function (DUF3679)
HOIIOEIH_03601 2.7e-219 spoIIP M stage II sporulation protein P
HOIIOEIH_03602 3.6e-202 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HOIIOEIH_03603 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HOIIOEIH_03604 1.2e-186 holA 2.7.7.7 L DNA polymerase III delta subunit
HOIIOEIH_03605 0.0 comEC S Competence protein ComEC
HOIIOEIH_03606 2.8e-102 comEB 3.5.4.12 F ComE operon protein 2
HOIIOEIH_03607 1.1e-94 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HOIIOEIH_03608 4.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOIIOEIH_03609 1.1e-135 yqeM Q Methyltransferase
HOIIOEIH_03610 1.3e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HOIIOEIH_03611 1.1e-98 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HOIIOEIH_03612 8.6e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOIIOEIH_03613 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HOIIOEIH_03614 3.2e-150 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HOIIOEIH_03615 1.1e-211 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HOIIOEIH_03616 2e-94 yqeG S hydrolase of the HAD superfamily
HOIIOEIH_03618 1.6e-137 yqeF E GDSL-like Lipase/Acylhydrolase
HOIIOEIH_03619 3.1e-128 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HOIIOEIH_03620 4e-97 yqeD S SNARE associated Golgi protein
HOIIOEIH_03621 4.1e-164 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HOIIOEIH_03622 2.2e-112 yqeB
HOIIOEIH_03623 7.1e-71 nucB M Deoxyribonuclease NucA/NucB
HOIIOEIH_03624 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOIIOEIH_03625 2.3e-35 cisA2 L Recombinase
HOIIOEIH_03627 5e-60 ykvN K HxlR-like helix-turn-helix
HOIIOEIH_03628 7e-133 IQ Enoyl-(Acyl carrier protein) reductase
HOIIOEIH_03629 6.2e-62 hosA K helix_turn_helix multiple antibiotic resistance protein
HOIIOEIH_03630 5.4e-60 2.8.1.7, 4.4.1.16 P Rhodanese Homology Domain
HOIIOEIH_03631 2.9e-53 ydcG S EVE domain
HOIIOEIH_03632 7.2e-66 S response regulator aspartate phosphatase
HOIIOEIH_03634 1.2e-89 lacR K Transcriptional regulator
HOIIOEIH_03635 8.2e-30 S Agrobacterium tumefaciens protein Atu4866
HOIIOEIH_03636 9.7e-93 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HOIIOEIH_03637 4.9e-167 yobL S Bacterial EndoU nuclease
HOIIOEIH_03638 3.5e-32
HOIIOEIH_03639 1.8e-23
HOIIOEIH_03640 5.7e-16 S Protein of unknown function (DUF4064)
HOIIOEIH_03642 1.9e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HOIIOEIH_03643 1.9e-89 K Transcriptional regulator PadR-like family
HOIIOEIH_03644 2.4e-95 yqaB E IrrE N-terminal-like domain
HOIIOEIH_03645 3.4e-40 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOIIOEIH_03646 5.7e-103 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HOIIOEIH_03647 2.5e-56 K transcriptional
HOIIOEIH_03648 5.2e-112 nfsA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HOIIOEIH_03649 1.1e-40 yrdF K ribonuclease inhibitor
HOIIOEIH_03651 3.3e-144 bltR K helix_turn_helix, mercury resistance
HOIIOEIH_03652 4.6e-203 blt EGP Major facilitator Superfamily
HOIIOEIH_03653 1.6e-79 bltD 2.3.1.57 K FR47-like protein
HOIIOEIH_03654 3.3e-98 flr S Flavin reductase like domain
HOIIOEIH_03655 1.3e-07 rocF 3.5.3.1, 3.5.3.11 E Arginase family
HOIIOEIH_03656 7.2e-118 bmrR K helix_turn_helix, mercury resistance
HOIIOEIH_03657 6.4e-08 1.3.1.9 S 2-nitropropane dioxygenase
HOIIOEIH_03658 1.4e-48 yjbR S YjbR
HOIIOEIH_03659 8.1e-292 epsA I Passenger-associated-transport-repeat
HOIIOEIH_03660 5.1e-107 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HOIIOEIH_03661 2e-89 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HOIIOEIH_03662 6.7e-184 yrpG C Aldo/keto reductase family
HOIIOEIH_03663 3.4e-144 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HOIIOEIH_03664 1.6e-39 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HOIIOEIH_03665 4.2e-139 S Alpha beta hydrolase
HOIIOEIH_03666 1.7e-60 T sh3 domain protein
HOIIOEIH_03667 1.6e-55 T sh3 domain protein
HOIIOEIH_03668 2.2e-35 yraG
HOIIOEIH_03669 7.8e-61 yraF M Spore coat protein
HOIIOEIH_03670 1.8e-217 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HOIIOEIH_03671 3.7e-25 yraE
HOIIOEIH_03672 2.6e-46 yraD M Spore coat protein
HOIIOEIH_03673 6.2e-43 yraB K helix_turn_helix, mercury resistance
HOIIOEIH_03674 8.1e-24 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HOIIOEIH_03675 2.4e-47 4.1.1.44 S Cupin domain
HOIIOEIH_03676 5.7e-189 adhA 1.1.1.1 C alcohol dehydrogenase
HOIIOEIH_03677 2.1e-88 yhbO 1.11.1.6, 3.5.1.124 S protease
HOIIOEIH_03678 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HOIIOEIH_03679 2.6e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HOIIOEIH_03680 9.3e-115 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HOIIOEIH_03681 1e-79 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HOIIOEIH_03682 4.1e-72 levD 2.7.1.202 G PTS system fructose IIA component
HOIIOEIH_03683 0.0 levR K PTS system fructose IIA component
HOIIOEIH_03686 1.1e-245 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HOIIOEIH_03687 1.9e-99 yrhP E LysE type translocator
HOIIOEIH_03688 5.5e-147 yrhO K Archaeal transcriptional regulator TrmB
HOIIOEIH_03689 6.2e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HOIIOEIH_03690 1.7e-143 rsiV S Protein of unknown function (DUF3298)
HOIIOEIH_03691 0.0 yrhL I Acyltransferase family
HOIIOEIH_03692 1.2e-40 yrhK S YrhK-like protein
HOIIOEIH_03693 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HOIIOEIH_03694 1e-99 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HOIIOEIH_03695 9.4e-87 yrhH Q methyltransferase
HOIIOEIH_03697 7.5e-141 focA P Formate nitrite
HOIIOEIH_03698 7e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HOIIOEIH_03699 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HOIIOEIH_03700 1e-76 yrhD S Protein of unknown function (DUF1641)
HOIIOEIH_03701 4.5e-208 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HOIIOEIH_03702 7e-167 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HOIIOEIH_03703 1.4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOIIOEIH_03704 1.5e-112 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HOIIOEIH_03705 1.7e-25 yrzA S Protein of unknown function (DUF2536)
HOIIOEIH_03706 1.4e-55 yrrS S Protein of unknown function (DUF1510)
HOIIOEIH_03707 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HOIIOEIH_03708 1.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOIIOEIH_03709 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HOIIOEIH_03710 1.5e-244 yegQ O COG0826 Collagenase and related proteases
HOIIOEIH_03711 7.3e-172 yegQ O Peptidase U32
HOIIOEIH_03712 4.2e-118 yrrM 2.1.1.104 S O-methyltransferase
HOIIOEIH_03713 1e-177 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HOIIOEIH_03714 3.9e-44 yrzB S Belongs to the UPF0473 family
HOIIOEIH_03715 6.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOIIOEIH_03716 1.7e-41 yrzL S Belongs to the UPF0297 family
HOIIOEIH_03717 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOIIOEIH_03718 1.6e-162 yrrI S AI-2E family transporter
HOIIOEIH_03719 3.6e-08 S Protein of unknown function (DUF3918)
HOIIOEIH_03720 9.8e-31 yrzR
HOIIOEIH_03721 1.2e-79 yrrD S protein conserved in bacteria
HOIIOEIH_03722 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HOIIOEIH_03723 1.4e-15 S COG0457 FOG TPR repeat
HOIIOEIH_03724 1.9e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HOIIOEIH_03725 4.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
HOIIOEIH_03726 1.2e-70 cymR K Transcriptional regulator
HOIIOEIH_03727 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HOIIOEIH_03728 1e-134 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HOIIOEIH_03729 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HOIIOEIH_03730 3.2e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
HOIIOEIH_03732 5.2e-239 lytH 3.5.1.28 M COG3103 SH3 domain protein
HOIIOEIH_03733 1.3e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HOIIOEIH_03734 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOIIOEIH_03735 1.1e-89 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOIIOEIH_03736 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HOIIOEIH_03737 1.2e-39 yrvD S Lipopolysaccharide assembly protein A domain
HOIIOEIH_03738 6.2e-77 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HOIIOEIH_03739 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HOIIOEIH_03740 8.8e-47 yrzD S Post-transcriptional regulator
HOIIOEIH_03741 2.5e-265 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOIIOEIH_03742 1.4e-105 yrbG S membrane
HOIIOEIH_03743 7.1e-72 yrzE S Protein of unknown function (DUF3792)
HOIIOEIH_03744 6.7e-38 yajC U Preprotein translocase subunit YajC
HOIIOEIH_03745 2e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HOIIOEIH_03746 7.7e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HOIIOEIH_03747 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HOIIOEIH_03748 2.8e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HOIIOEIH_03749 2.2e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HOIIOEIH_03750 3.6e-88 bofC S BofC C-terminal domain
HOIIOEIH_03751 1.8e-245 csbX EGP Major facilitator Superfamily
HOIIOEIH_03752 2.2e-185 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HOIIOEIH_03753 2.2e-114 yrzF T serine threonine protein kinase
HOIIOEIH_03755 9.4e-251 alsT E Sodium alanine symporter
HOIIOEIH_03756 1.6e-118 yebC K transcriptional regulatory protein
HOIIOEIH_03757 8.5e-41 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HOIIOEIH_03758 5.8e-118 safA M spore coat assembly protein SafA
HOIIOEIH_03759 1.3e-204 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HOIIOEIH_03760 3.2e-145 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HOIIOEIH_03761 3.9e-274 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HOIIOEIH_03762 6.1e-216 nifS 2.8.1.7 E Cysteine desulfurase
HOIIOEIH_03763 2.8e-91 niaR S small molecule binding protein (contains 3H domain)
HOIIOEIH_03764 8.7e-159 pheA 4.2.1.51 E Prephenate dehydratase
HOIIOEIH_03765 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HOIIOEIH_03766 5.2e-229 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOIIOEIH_03767 7.4e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HOIIOEIH_03768 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HOIIOEIH_03769 5.3e-56 ysxB J ribosomal protein
HOIIOEIH_03770 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HOIIOEIH_03771 5.6e-158 spoIVFB S Stage IV sporulation protein
HOIIOEIH_03772 1e-142 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HOIIOEIH_03773 2.1e-143 minD D Belongs to the ParA family
HOIIOEIH_03774 6e-107 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HOIIOEIH_03775 6.6e-82 mreD M shape-determining protein
HOIIOEIH_03776 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HOIIOEIH_03777 2e-183 mreB D Rod shape-determining protein MreB
HOIIOEIH_03778 9.4e-124 radC E Belongs to the UPF0758 family
HOIIOEIH_03779 5.9e-100 maf D septum formation protein Maf
HOIIOEIH_03780 1.4e-160 spoIIB S Sporulation related domain
HOIIOEIH_03781 2.4e-117 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HOIIOEIH_03782 7.3e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HOIIOEIH_03783 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HOIIOEIH_03784 3.1e-24
HOIIOEIH_03785 1.4e-184 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HOIIOEIH_03786 1.6e-132 spoVID M stage VI sporulation protein D
HOIIOEIH_03787 2.6e-244 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HOIIOEIH_03788 5.3e-181 hemB 4.2.1.24 H Belongs to the ALAD family
HOIIOEIH_03789 7.9e-135 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HOIIOEIH_03790 5.8e-169 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HOIIOEIH_03791 3.6e-146 hemX O cytochrome C
HOIIOEIH_03792 4e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HOIIOEIH_03793 2.3e-87 ysxD
HOIIOEIH_03794 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HOIIOEIH_03795 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HOIIOEIH_03796 5.2e-306 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HOIIOEIH_03797 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HOIIOEIH_03798 3.9e-224 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HOIIOEIH_03799 2.4e-184 ysoA H Tetratricopeptide repeat
HOIIOEIH_03800 4.5e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOIIOEIH_03801 3.5e-274 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOIIOEIH_03802 5.9e-197 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HOIIOEIH_03803 1.3e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOIIOEIH_03804 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOIIOEIH_03805 1.6e-83 ilvN 2.2.1.6 E Acetolactate synthase
HOIIOEIH_03806 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HOIIOEIH_03808 1.8e-75 ysnE K acetyltransferase
HOIIOEIH_03809 6.8e-121 ysnF S protein conserved in bacteria
HOIIOEIH_03811 9.4e-89 ysnB S Phosphoesterase
HOIIOEIH_03812 1.5e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOIIOEIH_03813 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HOIIOEIH_03814 1.7e-191 gerM S COG5401 Spore germination protein
HOIIOEIH_03815 1.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HOIIOEIH_03816 1.5e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HOIIOEIH_03817 3.3e-30 gerE K Transcriptional regulator
HOIIOEIH_03818 4.4e-74 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HOIIOEIH_03819 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HOIIOEIH_03820 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HOIIOEIH_03821 2.4e-107 sdhC C succinate dehydrogenase
HOIIOEIH_03822 1.6e-79 yslB S Protein of unknown function (DUF2507)
HOIIOEIH_03823 1.8e-210 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HOIIOEIH_03824 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HOIIOEIH_03825 2e-52 trxA O Belongs to the thioredoxin family
HOIIOEIH_03826 5.8e-296 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HOIIOEIH_03828 2.9e-171 etfA C Electron transfer flavoprotein
HOIIOEIH_03829 7.2e-133 etfB C Electron transfer flavoprotein
HOIIOEIH_03830 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HOIIOEIH_03831 4.1e-96 fadR K Transcriptional regulator
HOIIOEIH_03832 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HOIIOEIH_03833 4.7e-67 yshE S membrane
HOIIOEIH_03834 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HOIIOEIH_03835 0.0 polX L COG1796 DNA polymerase IV (family X)
HOIIOEIH_03836 9.5e-84 cvpA S membrane protein, required for colicin V production
HOIIOEIH_03837 1.7e-38 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HOIIOEIH_03838 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOIIOEIH_03839 6.6e-43 L COG2963 Transposase and inactivated derivatives
HOIIOEIH_03840 2.3e-142 L Molecular Function DNA binding, Biological Process DNA recombination
HOIIOEIH_03841 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOIIOEIH_03842 6.8e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HOIIOEIH_03843 1.1e-122 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOIIOEIH_03844 4.5e-32 sspI S Belongs to the SspI family
HOIIOEIH_03845 3.2e-190 ysfB KT regulator
HOIIOEIH_03846 2e-253 glcD 1.1.3.15 C Glycolate oxidase subunit
HOIIOEIH_03847 6.6e-251 glcF C Glycolate oxidase
HOIIOEIH_03848 3.6e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
HOIIOEIH_03849 0.0 cstA T Carbon starvation protein
HOIIOEIH_03850 1.8e-79 S Putative adhesin
HOIIOEIH_03851 1.3e-83 S Protein of unknown function (DUF1700)
HOIIOEIH_03852 7.5e-55 K PadR family transcriptional regulator
HOIIOEIH_03853 1.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HOIIOEIH_03854 9.9e-144 araQ G transport system permease
HOIIOEIH_03855 1.2e-166 araP G carbohydrate transport
HOIIOEIH_03856 1.2e-241 araN G carbohydrate transport
HOIIOEIH_03857 4.7e-208 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HOIIOEIH_03858 1.6e-138 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HOIIOEIH_03859 9.3e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HOIIOEIH_03860 1.2e-302 araB 2.7.1.16 C Belongs to the ribulokinase family
HOIIOEIH_03861 5.2e-289 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HOIIOEIH_03862 1e-160 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HOIIOEIH_03863 5.4e-203 ysdC G COG1363 Cellulase M and related proteins
HOIIOEIH_03864 1.6e-67 ysdB S Sigma-w pathway protein YsdB
HOIIOEIH_03865 9.2e-43 ysdA S Membrane
HOIIOEIH_03866 1.3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HOIIOEIH_03867 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HOIIOEIH_03868 9.6e-80 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HOIIOEIH_03871 6.5e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HOIIOEIH_03872 1.6e-47 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HOIIOEIH_03873 3.3e-127 lytT T COG3279 Response regulator of the LytR AlgR family
HOIIOEIH_03874 1.1e-309 lytS 2.7.13.3 T Histidine kinase
HOIIOEIH_03875 2.3e-147 ysaA S HAD-hyrolase-like
HOIIOEIH_03876 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOIIOEIH_03878 5.8e-152 ytxC S YtxC-like family
HOIIOEIH_03879 7.4e-107 ytxB S SNARE associated Golgi protein
HOIIOEIH_03880 1.4e-153 dnaI L Primosomal protein DnaI
HOIIOEIH_03881 3.5e-258 dnaB L Membrane attachment protein
HOIIOEIH_03882 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOIIOEIH_03883 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HOIIOEIH_03884 9.1e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOIIOEIH_03885 2.2e-66 ytcD K Transcriptional regulator
HOIIOEIH_03886 4.9e-197 ytbD EGP Major facilitator Superfamily
HOIIOEIH_03887 2.6e-152 ytbE S reductase
HOIIOEIH_03888 5.3e-94 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HOIIOEIH_03889 1.9e-107 ytaF P Probably functions as a manganese efflux pump
HOIIOEIH_03890 1.6e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HOIIOEIH_03891 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOIIOEIH_03892 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HOIIOEIH_03893 3.1e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_03894 7.6e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HOIIOEIH_03895 4.5e-241 icd 1.1.1.42 C isocitrate
HOIIOEIH_03896 4.4e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
HOIIOEIH_03897 2.3e-70 yeaL S membrane
HOIIOEIH_03898 4.2e-190 ytvI S sporulation integral membrane protein YtvI
HOIIOEIH_03899 2.1e-61 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HOIIOEIH_03900 4.7e-297 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HOIIOEIH_03901 2.2e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HOIIOEIH_03902 3.7e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HOIIOEIH_03903 4.1e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HOIIOEIH_03904 7.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HOIIOEIH_03905 0.0 dnaE 2.7.7.7 L DNA polymerase
HOIIOEIH_03906 6e-55 ytrH S Sporulation protein YtrH
HOIIOEIH_03907 6.9e-68 ytrI
HOIIOEIH_03908 3.5e-28
HOIIOEIH_03909 1.7e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HOIIOEIH_03910 2.5e-44 ytpI S YtpI-like protein
HOIIOEIH_03911 2.3e-240 ytoI K transcriptional regulator containing CBS domains
HOIIOEIH_03912 1.1e-129 ytkL S Belongs to the UPF0173 family
HOIIOEIH_03913 7.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOIIOEIH_03915 6e-263 argH 4.3.2.1 E argininosuccinate lyase
HOIIOEIH_03916 2.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HOIIOEIH_03917 1.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HOIIOEIH_03918 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOIIOEIH_03919 2.8e-158 ytxK 2.1.1.72 L DNA methylase
HOIIOEIH_03920 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HOIIOEIH_03921 6.3e-68 ytfJ S Sporulation protein YtfJ
HOIIOEIH_03922 1.9e-105 ytfI S Protein of unknown function (DUF2953)
HOIIOEIH_03923 5.4e-81 yteJ S RDD family
HOIIOEIH_03924 1.8e-176 sppA OU signal peptide peptidase SppA
HOIIOEIH_03925 9.1e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOIIOEIH_03926 2.4e-300 ytcJ S amidohydrolase
HOIIOEIH_03927 1.3e-298 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HOIIOEIH_03928 7.7e-29 sspB S spore protein
HOIIOEIH_03929 8.7e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOIIOEIH_03930 6.8e-196 iscS2 2.8.1.7 E Cysteine desulfurase
HOIIOEIH_03931 1.6e-172 braB E Component of the transport system for branched-chain amino acids
HOIIOEIH_03932 1.1e-263 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HOIIOEIH_03933 1.9e-144 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HOIIOEIH_03934 1.9e-107 yttP K Transcriptional regulator
HOIIOEIH_03935 1.9e-86 ytsP 1.8.4.14 T GAF domain-containing protein
HOIIOEIH_03936 1.1e-290 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HOIIOEIH_03937 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HOIIOEIH_03939 2.4e-234 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOIIOEIH_03940 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HOIIOEIH_03941 4.4e-120 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HOIIOEIH_03942 8.2e-114 acuB S Domain in cystathionine beta-synthase and other proteins.
HOIIOEIH_03943 1e-215 acuC BQ histone deacetylase
HOIIOEIH_03944 7.9e-118 motS N Flagellar motor protein
HOIIOEIH_03945 1.5e-144 motA N flagellar motor
HOIIOEIH_03946 1.2e-180 ccpA K catabolite control protein A
HOIIOEIH_03947 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HOIIOEIH_03948 9.1e-53 ytxJ O Protein of unknown function (DUF2847)
HOIIOEIH_03949 6.6e-17 ytxH S COG4980 Gas vesicle protein
HOIIOEIH_03950 1.4e-13 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HOIIOEIH_03951 3.4e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HOIIOEIH_03952 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HOIIOEIH_03953 9.4e-104 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOIIOEIH_03954 4.1e-147 ytpQ S Belongs to the UPF0354 family
HOIIOEIH_03955 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HOIIOEIH_03956 3.8e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HOIIOEIH_03957 1.4e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HOIIOEIH_03958 3.1e-50 ytzB S small secreted protein
HOIIOEIH_03959 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HOIIOEIH_03960 2.1e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HOIIOEIH_03961 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HOIIOEIH_03962 2e-45 ytzH S YtzH-like protein
HOIIOEIH_03963 4.6e-151 ytmP 2.7.1.89 M Phosphotransferase
HOIIOEIH_03964 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HOIIOEIH_03965 1.8e-175 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HOIIOEIH_03966 1.4e-159 ytlQ
HOIIOEIH_03967 3e-96 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HOIIOEIH_03968 3.4e-169 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HOIIOEIH_03969 2.4e-256 pepV 3.5.1.18 E Dipeptidase
HOIIOEIH_03970 2.8e-222 pbuO S permease
HOIIOEIH_03971 4.8e-181 ythQ U Bacterial ABC transporter protein EcsB
HOIIOEIH_03972 1.9e-124 ythP V ABC transporter
HOIIOEIH_03973 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HOIIOEIH_03974 1.2e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HOIIOEIH_03975 3.7e-288 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HOIIOEIH_03976 7.9e-227 ytfP S HI0933-like protein
HOIIOEIH_03977 2.8e-269 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HOIIOEIH_03978 3.1e-26 yteV S Sporulation protein Cse60
HOIIOEIH_03979 3.2e-105 yteU S Integral membrane protein
HOIIOEIH_03980 3.9e-248 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HOIIOEIH_03981 6e-65 yteS G transport
HOIIOEIH_03982 2.3e-212 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HOIIOEIH_03983 6.4e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HOIIOEIH_03984 0.0 ytdP K Transcriptional regulator
HOIIOEIH_03985 1.3e-282 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HOIIOEIH_03986 2.3e-151 ytcP G COG0395 ABC-type sugar transport system, permease component
HOIIOEIH_03987 2.2e-134 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HOIIOEIH_03988 1.6e-203 bioI 1.14.14.46 C Cytochrome P450
HOIIOEIH_03989 6.6e-187 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HOIIOEIH_03990 1.3e-117 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HOIIOEIH_03991 8.5e-202 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HOIIOEIH_03992 1.1e-250 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HOIIOEIH_03993 9.3e-130 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HOIIOEIH_03994 6.9e-60 S Psort location CytoplasmicMembrane, score
HOIIOEIH_03995 3e-162 ytaP S Acetyl xylan esterase (AXE1)
HOIIOEIH_03996 2.4e-184 msmR K Transcriptional regulator
HOIIOEIH_03997 9.8e-236 msmE G Bacterial extracellular solute-binding protein
HOIIOEIH_03998 1e-165 amyD P ABC transporter
HOIIOEIH_03999 2e-141 amyC P ABC transporter (permease)
HOIIOEIH_04000 1.3e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HOIIOEIH_04001 6.9e-50 ytwF P Sulfurtransferase
HOIIOEIH_04002 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOIIOEIH_04003 4.5e-55 ytvB S Protein of unknown function (DUF4257)
HOIIOEIH_04004 1.6e-135 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HOIIOEIH_04005 6.4e-205 yttB EGP Major facilitator Superfamily
HOIIOEIH_04006 5.9e-39 yttA 2.7.13.3 S Pfam Transposase IS66
HOIIOEIH_04007 0.0 bceB V ABC transporter (permease)
HOIIOEIH_04008 7.6e-135 bceA V ABC transporter, ATP-binding protein
HOIIOEIH_04009 1.4e-173 T PhoQ Sensor
HOIIOEIH_04010 6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOIIOEIH_04011 1.2e-228 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HOIIOEIH_04012 3.2e-124 ytrE V ABC transporter, ATP-binding protein
HOIIOEIH_04013 4.1e-141
HOIIOEIH_04014 5.9e-148 P ABC-2 family transporter protein
HOIIOEIH_04015 1.2e-160 ytrB P abc transporter atp-binding protein
HOIIOEIH_04016 6.2e-64 ytrA K GntR family transcriptional regulator
HOIIOEIH_04018 1.9e-40 ytzC S Protein of unknown function (DUF2524)
HOIIOEIH_04019 3.1e-189 yhcC S Fe-S oxidoreductase
HOIIOEIH_04020 1.3e-102 ytqB J Putative rRNA methylase
HOIIOEIH_04021 1.2e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HOIIOEIH_04022 7.5e-146 ytpA 3.1.1.5 I Alpha beta hydrolase
HOIIOEIH_04023 3.6e-56 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HOIIOEIH_04024 5.3e-243 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HOIIOEIH_04025 0.0 asnB 6.3.5.4 E Asparagine synthase
HOIIOEIH_04026 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOIIOEIH_04027 3.8e-306 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HOIIOEIH_04028 4.7e-38 ytmB S Protein of unknown function (DUF2584)
HOIIOEIH_04029 5.7e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HOIIOEIH_04030 7.8e-183 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HOIIOEIH_04031 1.7e-142 ytlC P ABC transporter
HOIIOEIH_04032 2.4e-139 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HOIIOEIH_04033 9.1e-86 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HOIIOEIH_04034 1.6e-62 ytkC S Bacteriophage holin family
HOIIOEIH_04035 1e-75 dps P Belongs to the Dps family
HOIIOEIH_04037 3e-67 ytkA S YtkA-like
HOIIOEIH_04038 1.3e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HOIIOEIH_04039 8.5e-99 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HOIIOEIH_04040 3.6e-41 rpmE2 J Ribosomal protein L31
HOIIOEIH_04041 2e-247 cydA 1.10.3.14 C oxidase, subunit
HOIIOEIH_04042 1.7e-185 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HOIIOEIH_04043 3.3e-24 S Domain of Unknown Function (DUF1540)
HOIIOEIH_04044 8e-144 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HOIIOEIH_04045 1.8e-208 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HOIIOEIH_04046 9.2e-133 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HOIIOEIH_04047 6.7e-162 troA P Belongs to the bacterial solute-binding protein 9 family
HOIIOEIH_04048 3e-212 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HOIIOEIH_04049 8.2e-263 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HOIIOEIH_04050 1.9e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HOIIOEIH_04051 3e-145 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HOIIOEIH_04052 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HOIIOEIH_04053 3.8e-261 menF 5.4.4.2 HQ Isochorismate synthase
HOIIOEIH_04054 1.1e-130 dksA T COG1734 DnaK suppressor protein
HOIIOEIH_04055 2.5e-144 galU 2.7.7.9 M Nucleotidyl transferase
HOIIOEIH_04056 1.6e-222 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HOIIOEIH_04057 1.5e-169 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HOIIOEIH_04058 2e-222 ytcC M Glycosyltransferase Family 4
HOIIOEIH_04060 6.7e-198 cotS S Seems to be required for the assembly of the CotSA protein in spores
HOIIOEIH_04061 3.1e-209 cotSA M Glycosyl transferases group 1
HOIIOEIH_04062 1.5e-197 cotI S Spore coat protein
HOIIOEIH_04063 2e-69 tspO T membrane
HOIIOEIH_04064 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HOIIOEIH_04065 3.4e-269 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HOIIOEIH_04066 1e-174 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HOIIOEIH_04067 6.6e-191 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HOIIOEIH_04068 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HOIIOEIH_04077 7.8e-08
HOIIOEIH_04078 1.3e-09
HOIIOEIH_04085 2e-08
HOIIOEIH_04090 3.4e-39 S COG NOG14552 non supervised orthologous group
HOIIOEIH_04091 1.2e-87 thiT S Thiamine transporter protein (Thia_YuaJ)
HOIIOEIH_04092 1.3e-88 M1-753 M FR47-like protein
HOIIOEIH_04093 1.3e-181 yuaG 3.4.21.72 S protein conserved in bacteria
HOIIOEIH_04094 4.8e-72 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HOIIOEIH_04095 5.3e-81 yuaE S DinB superfamily
HOIIOEIH_04096 2.1e-100 yuaD
HOIIOEIH_04097 3e-226 gbsB 1.1.1.1 C alcohol dehydrogenase
HOIIOEIH_04098 1.6e-277 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HOIIOEIH_04099 1.8e-90 yuaC K Belongs to the GbsR family
HOIIOEIH_04100 3.8e-80 yuaB
HOIIOEIH_04101 8.2e-117 ktrA P COG0569 K transport systems, NAD-binding component
HOIIOEIH_04102 7.1e-229 ktrB P Potassium
HOIIOEIH_04103 1e-38 yiaA S yiaA/B two helix domain
HOIIOEIH_04104 6.7e-148 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HOIIOEIH_04105 8.7e-247 yubD P Major Facilitator Superfamily
HOIIOEIH_04106 1.6e-85 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HOIIOEIH_04107 1.2e-44 S YolD-like protein
HOIIOEIH_04108 9e-60 V Abortive infection bacteriophage resistance protein
HOIIOEIH_04109 1.2e-27 K Helix-turn-helix domain
HOIIOEIH_04113 3.1e-125 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HOIIOEIH_04114 3.5e-31 xhlB S SPP1 phage holin
HOIIOEIH_04115 2.6e-32 xhlA S Haemolysin XhlA
HOIIOEIH_04120 5.4e-225 S peptidoglycan catabolic process
HOIIOEIH_04121 4.4e-50
HOIIOEIH_04122 3.4e-140
HOIIOEIH_04123 6.4e-29 S Phage tail assembly chaperone protein, TAC
HOIIOEIH_04124 1.8e-09 chiB 3.2.1.14 GH18 G Belongs to the glycosyl hydrolase 18 family
HOIIOEIH_04125 1.5e-33 S Phage tail tube protein
HOIIOEIH_04126 1.7e-29 S Protein of unknown function (DUF3168)
HOIIOEIH_04127 3.4e-36 S Bacteriophage HK97-gp10, putative tail-component
HOIIOEIH_04128 7.7e-26 S Phage head-tail joining protein
HOIIOEIH_04129 3.2e-28 S Phage gp6-like head-tail connector protein
HOIIOEIH_04131 2.6e-116 gpG
HOIIOEIH_04133 2.2e-42 S Phage minor structural protein GP20
HOIIOEIH_04135 4.4e-92 S Phage Mu protein F like protein
HOIIOEIH_04136 5.4e-121 S Phage portal protein, SPP1 Gp6-like
HOIIOEIH_04137 3.4e-196 S Phage terminase large subunit
HOIIOEIH_04138 1.4e-45 L Terminase small subunit
HOIIOEIH_04141 5.6e-68 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)