ORF_ID e_value Gene_name EC_number CAZy COGs Description
HKLABNOI_00002 1e-100
HKLABNOI_00003 6.7e-19
HKLABNOI_00004 2.1e-32
HKLABNOI_00005 2.4e-132 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKLABNOI_00006 4.9e-15 dnaX 2.4.99.16, 2.7.7.7 GH13 D cell septum assembly
HKLABNOI_00009 1.7e-81 S Protein conserved in bacteria
HKLABNOI_00013 9.1e-35
HKLABNOI_00015 7.7e-107 L Psort location Cytoplasmic, score
HKLABNOI_00016 0.0 res_1 3.1.21.5 S DEAD-like helicases superfamily
HKLABNOI_00017 1.1e-200 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
HKLABNOI_00018 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKLABNOI_00019 5.9e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HKLABNOI_00021 2.7e-103
HKLABNOI_00022 9.5e-89 sdaAB 4.3.1.17 E L-serine dehydratase
HKLABNOI_00023 5.8e-147 sdaAA 4.3.1.17 E L-serine dehydratase
HKLABNOI_00024 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
HKLABNOI_00025 4.8e-160 yjlA EG membrane
HKLABNOI_00026 4.8e-80 3.4.21.89 S RDD family
HKLABNOI_00027 7.5e-153 K sequence-specific DNA binding
HKLABNOI_00028 5.2e-145 V ABC transporter, ATP-binding protein
HKLABNOI_00029 2.3e-80 S ABC-2 family transporter protein
HKLABNOI_00030 1.4e-146 K sequence-specific DNA binding
HKLABNOI_00031 1.8e-84
HKLABNOI_00032 1.1e-75 yfiQ K Acetyltransferase (GNAT) domain
HKLABNOI_00033 1.1e-141 S ABC-2 family transporter protein
HKLABNOI_00034 5.8e-141 S ABC-2 family transporter protein
HKLABNOI_00035 8e-185 S AAA domain, putative AbiEii toxin, Type IV TA system
HKLABNOI_00036 4.8e-80
HKLABNOI_00037 5.7e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKLABNOI_00038 1.2e-186 desK 2.7.13.3 T Histidine kinase
HKLABNOI_00039 2.6e-132 yvfS V ABC-2 type transporter
HKLABNOI_00040 4.8e-157 XK27_09825 V 'abc transporter, ATP-binding protein
HKLABNOI_00043 9e-170 fabH 2.3.1.180 I synthase III
HKLABNOI_00044 7.7e-241 6.2.1.30 H Coenzyme F390 synthetase
HKLABNOI_00045 6.9e-150 gumP S Metallo-beta-lactamase superfamily
HKLABNOI_00046 3.2e-178 ybjS 1.1.1.133, 5.1.3.13 M NAD dependent epimerase dehydratase family protein
HKLABNOI_00047 1.5e-228 2.4.1.276 GT1 CG Glycosyltransferase family 28 C-terminal domain
HKLABNOI_00048 1.8e-107 1.1.1.105 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLABNOI_00049 4.7e-197 ugcG 2.4.1.80 GT21 M transferase activity, transferring glycosyl groups
HKLABNOI_00050 3.1e-100
HKLABNOI_00051 1.3e-208 2.4.1.276 GT1 CG transferase activity, transferring hexosyl groups
HKLABNOI_00053 1.8e-203 anK3 G response to abiotic stimulus
HKLABNOI_00054 0.0 hscC O Belongs to the heat shock protein 70 family
HKLABNOI_00055 2.3e-165 yocS S Transporter
HKLABNOI_00056 2.6e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
HKLABNOI_00057 1.9e-130 yvfS V Transporter
HKLABNOI_00058 3.1e-156 XK27_09825 V abc transporter atp-binding protein
HKLABNOI_00059 7e-15 liaI KT membrane
HKLABNOI_00060 1.5e-30 liaI KT membrane
HKLABNOI_00061 6.1e-93 XK27_05000 S metal cluster binding
HKLABNOI_00062 0.0 V ABC transporter (permease)
HKLABNOI_00063 1.1e-133 macB2 V ABC transporter, ATP-binding protein
HKLABNOI_00064 2.5e-162 T Histidine kinase
HKLABNOI_00065 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLABNOI_00066 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKLABNOI_00067 1.2e-222 pbuX F xanthine permease
HKLABNOI_00068 2.3e-274 V (ABC) transporter
HKLABNOI_00069 5.7e-144 K sequence-specific DNA binding
HKLABNOI_00070 1.8e-240 norM V Multidrug efflux pump
HKLABNOI_00072 3.3e-180 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKLABNOI_00073 1.1e-229 brnQ E Component of the transport system for branched-chain amino acids
HKLABNOI_00074 1.5e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKLABNOI_00075 4e-59 S Protein of unknown function (DUF3290)
HKLABNOI_00076 2.8e-106 S Protein of unknown function (DUF421)
HKLABNOI_00077 1.1e-16 csbD S CsbD-like
HKLABNOI_00078 2.2e-109 S Carbohydrate-binding domain-containing protein Cthe_2159
HKLABNOI_00079 6.8e-51 XK27_01300 S ASCH
HKLABNOI_00080 1.4e-216 yfnA E amino acid
HKLABNOI_00081 0.0 S dextransucrase activity
HKLABNOI_00082 8.6e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HKLABNOI_00083 2e-42 S Sugar efflux transporter for intercellular exchange
HKLABNOI_00084 1.6e-205 P FtsX-like permease family
HKLABNOI_00085 3.9e-122 V abc transporter atp-binding protein
HKLABNOI_00086 8.1e-97 K WHG domain
HKLABNOI_00087 1.2e-171 ydhF S Aldo keto reductase
HKLABNOI_00088 4.9e-07 S Protein of unknown function (DUF3169)
HKLABNOI_00089 2.5e-27 XK27_07105 K transcriptional
HKLABNOI_00090 2.8e-35
HKLABNOI_00091 5.8e-100 XK27_02070 S nitroreductase
HKLABNOI_00092 1.9e-150 1.13.11.2 S glyoxalase
HKLABNOI_00093 2.6e-74 ywnA K Transcriptional regulator
HKLABNOI_00094 1.1e-153 E Alpha/beta hydrolase of unknown function (DUF915)
HKLABNOI_00095 1.1e-223 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLABNOI_00096 3.7e-168 bcrA V abc transporter atp-binding protein
HKLABNOI_00097 8.1e-129 S ABC-2 family transporter protein
HKLABNOI_00098 2.5e-45 S Domain of unknown function (DUF4352)
HKLABNOI_00099 5.8e-147 T PhoQ Sensor
HKLABNOI_00100 1.1e-121 T Xre family transcriptional regulator
HKLABNOI_00101 3e-108 drgA C nitroreductase
HKLABNOI_00102 6.9e-103 yoaK S Protein of unknown function (DUF1275)
HKLABNOI_00103 4e-40 DJ nuclease activity
HKLABNOI_00104 2.5e-30 XK27_10490
HKLABNOI_00105 9.2e-158 yvgN C reductase
HKLABNOI_00106 7.1e-209 S Tetratricopeptide repeat
HKLABNOI_00107 0.0 lacL 3.2.1.23 G -beta-galactosidase
HKLABNOI_00108 0.0 lacS G transporter
HKLABNOI_00109 1.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HKLABNOI_00110 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKLABNOI_00111 1.7e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HKLABNOI_00112 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKLABNOI_00113 3.2e-181 galR K Transcriptional regulator
HKLABNOI_00114 1.4e-308 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
HKLABNOI_00115 1.9e-226 vncS 2.7.13.3 T Histidine kinase
HKLABNOI_00116 1.5e-115 K Response regulator receiver domain protein
HKLABNOI_00117 6e-239 vex3 V Efflux ABC transporter, permease protein
HKLABNOI_00118 1.5e-107 vex2 V abc transporter atp-binding protein
HKLABNOI_00119 3.2e-178 vex1 V Efflux ABC transporter, permease protein
HKLABNOI_00120 1.9e-283 XK27_07020 S Belongs to the UPF0371 family
HKLABNOI_00122 1.9e-195 gldA 1.1.1.6 C glycerol dehydrogenase
HKLABNOI_00123 8.5e-179 XK27_10475 S oxidoreductase
HKLABNOI_00124 5.7e-59 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
HKLABNOI_00125 2.6e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
HKLABNOI_00126 4.5e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
HKLABNOI_00127 2.8e-227 thrE K Psort location CytoplasmicMembrane, score
HKLABNOI_00128 0.0 M Putative cell wall binding repeat
HKLABNOI_00129 1.2e-33 S Immunity protein 41
HKLABNOI_00130 0.0 pepO 3.4.24.71 O Peptidase family M13
HKLABNOI_00132 1e-14 S integral membrane protein
HKLABNOI_00133 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
HKLABNOI_00134 3.4e-108 yhfC S Putative membrane peptidase family (DUF2324)
HKLABNOI_00135 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HKLABNOI_00137 4.4e-66
HKLABNOI_00138 1.7e-255 S dextransucrase activity
HKLABNOI_00139 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HKLABNOI_00140 0.0 S dextransucrase activity
HKLABNOI_00141 0.0 S dextransucrase activity
HKLABNOI_00142 0.0 S dextransucrase activity
HKLABNOI_00143 1.3e-90 M Putative cell wall binding repeat
HKLABNOI_00144 0.0 S dextransucrase activity
HKLABNOI_00145 1.9e-101 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HKLABNOI_00146 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HKLABNOI_00147 1.3e-292 S dextransucrase activity
HKLABNOI_00148 1.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKLABNOI_00149 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLABNOI_00150 1.2e-235 dltB M Membrane protein involved in D-alanine export
HKLABNOI_00151 4.2e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLABNOI_00152 0.0 XK27_10035 V abc transporter atp-binding protein
HKLABNOI_00153 5e-291 yfiB1 V abc transporter atp-binding protein
HKLABNOI_00154 5.4e-99 pvaA M lytic transglycosylase activity
HKLABNOI_00155 5.5e-178 ndpA S 37-kD nucleoid-associated bacterial protein
HKLABNOI_00156 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKLABNOI_00157 1.8e-102 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKLABNOI_00158 2e-141 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKLABNOI_00159 1.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKLABNOI_00160 5.1e-110 tdk 2.7.1.21 F thymidine kinase
HKLABNOI_00161 9.9e-183 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HKLABNOI_00162 1.9e-152 gst O Glutathione S-transferase
HKLABNOI_00163 5.5e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HKLABNOI_00164 4.9e-168 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKLABNOI_00165 4.4e-45 rpmE2 J 50S ribosomal protein L31
HKLABNOI_00166 6.7e-229 mntH P Mn2 and Fe2 transporters of the NRAMP family
HKLABNOI_00167 1.6e-161 ypuA S secreted protein
HKLABNOI_00168 1.2e-70 yaeR E COG0346 Lactoylglutathione lyase and related lyases
HKLABNOI_00169 3.9e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HKLABNOI_00170 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKLABNOI_00171 2.2e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKLABNOI_00172 3.9e-254 noxE P NADH oxidase
HKLABNOI_00173 5.6e-294 yfmM S abc transporter atp-binding protein
HKLABNOI_00174 1.8e-82 XK27_01265 S ECF-type riboflavin transporter, S component
HKLABNOI_00175 6.5e-151 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HKLABNOI_00176 6.3e-85 S ECF-type riboflavin transporter, S component
HKLABNOI_00178 6.1e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKLABNOI_00179 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HKLABNOI_00181 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKLABNOI_00182 2.3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKLABNOI_00183 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKLABNOI_00184 2.4e-22 WQ51_00220 K Helix-turn-helix domain
HKLABNOI_00185 5.9e-89 S Protein of unknown function (DUF3278)
HKLABNOI_00186 0.0 smc D Required for chromosome condensation and partitioning
HKLABNOI_00187 7.1e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKLABNOI_00188 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKLABNOI_00189 1.4e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKLABNOI_00190 4.8e-122 alkD L Dna alkylation repair
HKLABNOI_00191 1.4e-295 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKLABNOI_00192 7.2e-89 pat 2.3.1.183 M acetyltransferase
HKLABNOI_00193 2.2e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKLABNOI_00195 1.3e-131 agrA KT Response regulator of the LytR AlgR family
HKLABNOI_00196 7.5e-231 2.7.13.3 T GHKL domain
HKLABNOI_00197 1.8e-48 L COG3547 Transposase and inactivated derivatives
HKLABNOI_00198 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
HKLABNOI_00200 7.7e-242 3.5.1.28 NU GBS Bsp-like repeat
HKLABNOI_00201 2e-23 M Psort location Cytoplasmic, score
HKLABNOI_00203 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKLABNOI_00204 9.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKLABNOI_00205 5.7e-201 V permease protein
HKLABNOI_00206 5.2e-122 macB V ABC transporter, ATP-binding protein
HKLABNOI_00207 8.3e-179 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKLABNOI_00208 3.6e-121 rsmJ 2.1.1.242 J Putative SAM-dependent methyltransferase
HKLABNOI_00209 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HKLABNOI_00210 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HKLABNOI_00211 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HKLABNOI_00212 2.1e-217 pyrP F uracil Permease
HKLABNOI_00213 1.8e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKLABNOI_00214 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKLABNOI_00215 2.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKLABNOI_00216 1.2e-166 fhuR K transcriptional regulator (lysR family)
HKLABNOI_00218 1.6e-41
HKLABNOI_00219 5.8e-69 K Helix-turn-helix
HKLABNOI_00223 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKLABNOI_00224 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HKLABNOI_00225 2.3e-07 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLABNOI_00226 1.3e-254 cycA E permease
HKLABNOI_00227 3.5e-39 ynzC S UPF0291 protein
HKLABNOI_00228 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HKLABNOI_00229 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HKLABNOI_00230 8.1e-219 S membrane
HKLABNOI_00231 5.7e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKLABNOI_00232 3.5e-294 nptA P COG1283 Na phosphate symporter
HKLABNOI_00233 3.6e-114 3.4.17.14, 3.5.1.28 NU amidase activity
HKLABNOI_00234 2.1e-83 S Bacterial inner membrane protein
HKLABNOI_00235 1.1e-142 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HKLABNOI_00236 2.1e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
HKLABNOI_00237 1.9e-53 glnB K Belongs to the P(II) protein family
HKLABNOI_00238 3.3e-228 amt P Ammonium Transporter
HKLABNOI_00239 1.3e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKLABNOI_00240 1.2e-54 yabA L Involved in initiation control of chromosome replication
HKLABNOI_00241 4.4e-133 yaaT S stage 0 sporulation protein
HKLABNOI_00242 3.3e-158 holB 2.7.7.7 L dna polymerase iii
HKLABNOI_00243 1e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKLABNOI_00245 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKLABNOI_00246 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKLABNOI_00247 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKLABNOI_00248 2.7e-217 ftsW D Belongs to the SEDS family
HKLABNOI_00249 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HKLABNOI_00250 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKLABNOI_00251 1.1e-156 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKLABNOI_00252 6.5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKLABNOI_00253 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKLABNOI_00254 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKLABNOI_00255 2e-121 atpB C it plays a direct role in the translocation of protons across the membrane
HKLABNOI_00256 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKLABNOI_00257 3.7e-293
HKLABNOI_00258 9.8e-217 dcm 2.1.1.37 H cytosine-specific methyltransferase
HKLABNOI_00259 1.7e-13
HKLABNOI_00260 7.7e-115 L reverse transcriptase
HKLABNOI_00261 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKLABNOI_00262 1.5e-15
HKLABNOI_00263 2.9e-99 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
HKLABNOI_00264 6.9e-104 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HKLABNOI_00267 3e-14 coiA 3.6.4.12 S Competence protein
HKLABNOI_00268 2.6e-16 T peptidase
HKLABNOI_00269 9.1e-148 rarD S Transporter
HKLABNOI_00270 4.5e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKLABNOI_00271 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HKLABNOI_00272 9.7e-134 yxkH G deacetylase
HKLABNOI_00273 4.6e-205 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HKLABNOI_00274 2.8e-126 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HKLABNOI_00275 3e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKLABNOI_00276 1.7e-185 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKLABNOI_00277 4.7e-224 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HKLABNOI_00278 2.8e-140 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKLABNOI_00279 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
HKLABNOI_00281 7.5e-135 agrA KT response regulator
HKLABNOI_00282 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HKLABNOI_00283 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKLABNOI_00284 8.7e-84 yxjI S LURP-one-related
HKLABNOI_00285 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HKLABNOI_00286 6.7e-119 yrrM 2.1.1.104 S O-Methyltransferase
HKLABNOI_00287 5.9e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
HKLABNOI_00288 0.0 pepF E oligoendopeptidase F
HKLABNOI_00289 1.5e-164 coiA 3.6.4.12 S Competence protein
HKLABNOI_00290 6.4e-279 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKLABNOI_00291 1e-104 S CAAX amino terminal protease family protein
HKLABNOI_00292 5.2e-167 K transcriptional regulator (lysR family)
HKLABNOI_00293 8.4e-159 S reductase
HKLABNOI_00294 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKLABNOI_00300 1.8e-51 bta 1.8.1.8 CO cell redox homeostasis
HKLABNOI_00301 1.6e-57 L thioesterase
HKLABNOI_00302 1.5e-141 S Macro domain protein
HKLABNOI_00303 2.4e-50 trxA O Belongs to the thioredoxin family
HKLABNOI_00304 1.7e-70 yccU S CoA-binding protein
HKLABNOI_00305 6.8e-142 tatD L Hydrolase, tatd
HKLABNOI_00306 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKLABNOI_00307 7.1e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKLABNOI_00309 4.1e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKLABNOI_00310 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HKLABNOI_00311 1.3e-111 thiN 2.7.6.2 H thiamine pyrophosphokinase
HKLABNOI_00312 1.1e-167 rmuC S RmuC domain protein
HKLABNOI_00313 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
HKLABNOI_00314 6.9e-142 purR 2.4.2.7 F operon repressor
HKLABNOI_00315 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKLABNOI_00316 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKLABNOI_00317 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKLABNOI_00318 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
HKLABNOI_00319 5.7e-102
HKLABNOI_00320 9.9e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HKLABNOI_00321 2.5e-86 S Fusaric acid resistance protein-like
HKLABNOI_00322 8.5e-63 glnR K Transcriptional regulator
HKLABNOI_00323 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
HKLABNOI_00324 9.5e-115 pscB M CHAP domain protein
HKLABNOI_00325 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKLABNOI_00326 3.3e-33 ykzG S Belongs to the UPF0356 family
HKLABNOI_00327 1.5e-118 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HKLABNOI_00328 1.5e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKLABNOI_00329 6.2e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKLABNOI_00330 1.1e-111 azlC E AzlC protein
HKLABNOI_00331 7.5e-47 azlD S branched-chain amino acid
HKLABNOI_00332 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKLABNOI_00333 4e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HKLABNOI_00334 8.5e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKLABNOI_00335 1.4e-26 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKLABNOI_00336 4.5e-89 cvpA S toxin biosynthetic process
HKLABNOI_00337 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKLABNOI_00338 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKLABNOI_00340 1.3e-34
HKLABNOI_00342 1e-223 mutY L A G-specific adenine glycosylase
HKLABNOI_00343 3.8e-43 XK27_05745
HKLABNOI_00344 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HKLABNOI_00345 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKLABNOI_00346 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKLABNOI_00348 1e-122 XK27_01040 S Protein of unknown function (DUF1129)
HKLABNOI_00349 2.9e-168 corA P COG0598 Mg2 and Co2 transporters
HKLABNOI_00350 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HKLABNOI_00357 1.9e-144 V 'abc transporter, ATP-binding protein
HKLABNOI_00359 5.9e-186 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HKLABNOI_00360 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
HKLABNOI_00361 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKLABNOI_00362 1.7e-61 yqhY S protein conserved in bacteria
HKLABNOI_00363 1.3e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKLABNOI_00364 1.1e-178 scrR K Transcriptional regulator
HKLABNOI_00365 2.7e-290 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
HKLABNOI_00366 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HKLABNOI_00367 2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HKLABNOI_00368 1.9e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKLABNOI_00370 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKLABNOI_00371 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKLABNOI_00372 1.9e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKLABNOI_00373 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKLABNOI_00374 3e-180 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKLABNOI_00375 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKLABNOI_00379 2.9e-31 yozG K Transcriptional regulator
HKLABNOI_00381 1.2e-177 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HKLABNOI_00382 2.4e-256 XK27_03190 S hydrolases of the HAD superfamily
HKLABNOI_00383 4.2e-103 yebC M Membrane
HKLABNOI_00384 1.5e-308 KT response to antibiotic
HKLABNOI_00385 5.7e-74 XK27_02470 K LytTr DNA-binding domain
HKLABNOI_00386 8.2e-120 liaI S membrane
HKLABNOI_00388 2e-109
HKLABNOI_00389 2.8e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HKLABNOI_00390 4.4e-166 dnaI L Primosomal protein DnaI
HKLABNOI_00391 2e-214 dnaB L Replication initiation and membrane attachment
HKLABNOI_00392 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKLABNOI_00393 6.6e-279 T PhoQ Sensor
HKLABNOI_00394 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLABNOI_00395 9e-90 yceD K metal-binding, possibly nucleic acid-binding protein
HKLABNOI_00396 2.2e-128 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HKLABNOI_00397 5.2e-235 P COG0168 Trk-type K transport systems, membrane components
HKLABNOI_00398 4.5e-115 ktrA P COG0569 K transport systems, NAD-binding component
HKLABNOI_00399 2.1e-146 cbiQ P cobalt transport
HKLABNOI_00400 7.4e-308 ykoD P abc transporter atp-binding protein
HKLABNOI_00401 6.7e-93 S UPF0397 protein
HKLABNOI_00402 1e-156 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HKLABNOI_00403 5.1e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HKLABNOI_00404 1.2e-99 metI P ABC transporter (Permease
HKLABNOI_00405 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKLABNOI_00406 4.5e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HKLABNOI_00407 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
HKLABNOI_00408 6.3e-138 ET ABC transporter substrate-binding protein
HKLABNOI_00409 6.3e-131 cbiO P ABC transporter
HKLABNOI_00410 1.9e-136 P cobalt transport protein
HKLABNOI_00411 3.9e-176 cbiM P PDGLE domain
HKLABNOI_00412 3.7e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HKLABNOI_00413 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HKLABNOI_00414 6.9e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HKLABNOI_00415 6.6e-78 ureE O enzyme active site formation
HKLABNOI_00416 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HKLABNOI_00417 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HKLABNOI_00418 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HKLABNOI_00419 6.8e-95 ureI S AmiS/UreI family transporter
HKLABNOI_00420 2.4e-198 S Domain of unknown function (DUF4173)
HKLABNOI_00421 1.3e-54 yhaI L Membrane
HKLABNOI_00422 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKLABNOI_00423 7.1e-156 K sequence-specific DNA binding
HKLABNOI_00424 5.4e-89 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HKLABNOI_00425 2.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKLABNOI_00426 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKLABNOI_00427 1.6e-244 trkA P Potassium transporter peripheral membrane component
HKLABNOI_00428 4.6e-258 trkH P Cation transport protein
HKLABNOI_00429 1.8e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
HKLABNOI_00430 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKLABNOI_00431 6.9e-96 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKLABNOI_00432 3.4e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKLABNOI_00433 1.2e-127 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HKLABNOI_00434 2.7e-85 ykuL S CBS domain
HKLABNOI_00435 1.6e-96 XK27_09740 S Phosphoesterase
HKLABNOI_00436 6.2e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKLABNOI_00437 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKLABNOI_00438 1.6e-36 yneF S UPF0154 protein
HKLABNOI_00439 4.1e-90 K transcriptional regulator
HKLABNOI_00440 6.9e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKLABNOI_00441 4.2e-12 ycdA S Domain of unknown function (DUF4352)
HKLABNOI_00442 2.1e-99 ybhL S Belongs to the BI1 family
HKLABNOI_00443 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HKLABNOI_00444 2.3e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKLABNOI_00445 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HKLABNOI_00446 1.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKLABNOI_00447 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKLABNOI_00448 5.1e-300 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKLABNOI_00449 2.5e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
HKLABNOI_00450 2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HKLABNOI_00451 4.8e-22
HKLABNOI_00452 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HKLABNOI_00453 2.3e-276 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HKLABNOI_00454 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HKLABNOI_00455 9.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKLABNOI_00456 5.4e-92 ypsA S Belongs to the UPF0398 family
HKLABNOI_00457 1.1e-107 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKLABNOI_00458 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKLABNOI_00459 1.4e-253 pepC 3.4.22.40 E aminopeptidase
HKLABNOI_00460 2.8e-73 yhaI S Protein of unknown function (DUF805)
HKLABNOI_00461 1e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKLABNOI_00462 9.7e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKLABNOI_00463 7e-213 macB_2 V FtsX-like permease family
HKLABNOI_00464 8.1e-120 yhcA V abc transporter atp-binding protein
HKLABNOI_00465 1.8e-122 mta K Transcriptional
HKLABNOI_00466 2.2e-30 S Protein of unknown function (DUF3021)
HKLABNOI_00467 2.6e-74 K COG3279 Response regulator of the LytR AlgR family
HKLABNOI_00468 3e-132 cylB V ABC-2 type transporter
HKLABNOI_00469 4.1e-153 cylA V abc transporter atp-binding protein
HKLABNOI_00470 2.6e-217 S COG1073 Hydrolases of the alpha beta superfamily
HKLABNOI_00471 1.6e-71 K transcriptional
HKLABNOI_00472 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKLABNOI_00473 5.5e-133 glcR K transcriptional regulator (DeoR family)
HKLABNOI_00474 2.3e-142 cof S Sucrose-6F-phosphate phosphohydrolase
HKLABNOI_00475 1.8e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HKLABNOI_00476 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HKLABNOI_00477 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
HKLABNOI_00478 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKLABNOI_00479 1.7e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKLABNOI_00480 1.4e-53 S TM2 domain
HKLABNOI_00481 1.2e-43
HKLABNOI_00483 1.2e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKLABNOI_00484 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKLABNOI_00485 1.4e-142 cmpC S abc transporter atp-binding protein
HKLABNOI_00486 0.0 WQ51_06230 S ABC transporter
HKLABNOI_00487 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKLABNOI_00488 6.5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HKLABNOI_00489 9.3e-144 cdsA 2.7.7.41 S Belongs to the CDS family
HKLABNOI_00490 9.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKLABNOI_00491 7.7e-47 yajC U protein transport
HKLABNOI_00492 6.1e-126 yeeN K transcriptional regulatory protein
HKLABNOI_00493 1.1e-276 V ABC transporter
HKLABNOI_00494 1.4e-153 Z012_04635 K sequence-specific DNA binding
HKLABNOI_00495 2.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
HKLABNOI_00496 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKLABNOI_00497 1.1e-108 L Transposase IS116 IS110 IS902
HKLABNOI_00498 9.2e-59 L MULE transposase domain
HKLABNOI_00499 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
HKLABNOI_00500 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
HKLABNOI_00501 1.1e-95 srlA G PTS system glucitol sorbitol-specific
HKLABNOI_00502 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
HKLABNOI_00503 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
HKLABNOI_00504 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLABNOI_00505 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
HKLABNOI_00506 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
HKLABNOI_00507 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HKLABNOI_00508 5.5e-159 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HKLABNOI_00509 1.9e-128 adcB P ABC transporter (Permease
HKLABNOI_00510 7.1e-135 adcC P ABC transporter, ATP-binding protein
HKLABNOI_00511 1e-70 adcR K transcriptional
HKLABNOI_00512 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKLABNOI_00513 6.2e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKLABNOI_00514 4.7e-26
HKLABNOI_00515 2.9e-273 sufB O assembly protein SufB
HKLABNOI_00516 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
HKLABNOI_00517 8.6e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKLABNOI_00518 7.7e-233 sufD O assembly protein SufD
HKLABNOI_00519 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HKLABNOI_00520 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
HKLABNOI_00521 1.6e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKLABNOI_00522 8.3e-18 S Protein of unknown function (DUF3021)
HKLABNOI_00523 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKLABNOI_00524 4.2e-273 glnP P ABC transporter
HKLABNOI_00525 2.2e-123 glnQ E abc transporter atp-binding protein
HKLABNOI_00526 3.1e-180 D nuclear chromosome segregation
HKLABNOI_00527 2.8e-84 V VanZ like family
HKLABNOI_00528 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKLABNOI_00529 1.7e-189 yhjX P Major Facilitator
HKLABNOI_00530 1.3e-106 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HKLABNOI_00531 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKLABNOI_00532 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HKLABNOI_00533 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HKLABNOI_00534 9.1e-72 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKLABNOI_00535 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKLABNOI_00536 3.1e-83 nrdI F Belongs to the NrdI family
HKLABNOI_00537 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HKLABNOI_00538 1.1e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKLABNOI_00539 2.5e-175 prmA J Ribosomal protein L11 methyltransferase
HKLABNOI_00540 2.1e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HKLABNOI_00541 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
HKLABNOI_00542 1.3e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKLABNOI_00543 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKLABNOI_00544 5.8e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKLABNOI_00545 2.3e-134 ykuT M mechanosensitive ion channel
HKLABNOI_00546 3.9e-87 sigH K DNA-templated transcription, initiation
HKLABNOI_00548 1.4e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKLABNOI_00549 2.5e-62 manO S protein conserved in bacteria
HKLABNOI_00550 2.5e-169 manN G PTS system mannose fructose sorbose family IID component
HKLABNOI_00551 4.5e-117 manM G pts system
HKLABNOI_00552 4e-176 manL 2.7.1.191 G pts system
HKLABNOI_00553 2.2e-66 manO S Protein conserved in bacteria
HKLABNOI_00554 5.9e-158 manN G PTS system mannose fructose sorbose family IID component
HKLABNOI_00555 5.7e-133 manY G pts system
HKLABNOI_00556 1.4e-168 manL 2.7.1.191 G pts system
HKLABNOI_00557 9.2e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HKLABNOI_00558 1.7e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HKLABNOI_00559 1.6e-247 pbuO S permease
HKLABNOI_00560 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HKLABNOI_00561 3e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
HKLABNOI_00562 2.8e-187 brpA K Transcriptional
HKLABNOI_00563 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
HKLABNOI_00564 7.1e-196 nusA K Participates in both transcription termination and antitermination
HKLABNOI_00565 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HKLABNOI_00566 8e-42 ylxQ J ribosomal protein
HKLABNOI_00567 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKLABNOI_00568 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKLABNOI_00569 2.2e-99 yvdD 3.2.2.10 S Belongs to the LOG family
HKLABNOI_00570 3.3e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HKLABNOI_00571 3.1e-270 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKLABNOI_00572 1.3e-288 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HKLABNOI_00573 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HKLABNOI_00574 7.4e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
HKLABNOI_00575 3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HKLABNOI_00576 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HKLABNOI_00577 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
HKLABNOI_00578 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKLABNOI_00579 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKLABNOI_00580 2.3e-70 ylbF S Belongs to the UPF0342 family
HKLABNOI_00581 1.1e-43 ylbG S UPF0298 protein
HKLABNOI_00582 1.7e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HKLABNOI_00583 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
HKLABNOI_00584 3.2e-138 livM E Belongs to the binding-protein-dependent transport system permease family
HKLABNOI_00585 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HKLABNOI_00586 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HKLABNOI_00587 3e-111 acuB S CBS domain
HKLABNOI_00588 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKLABNOI_00589 6.5e-108 yvyE 3.4.13.9 S YigZ family
HKLABNOI_00590 5.7e-239 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HKLABNOI_00591 6.5e-98 comFC K competence protein
HKLABNOI_00592 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKLABNOI_00593 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLABNOI_00594 3.2e-220 vicK 2.7.13.3 T Histidine kinase
HKLABNOI_00595 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HKLABNOI_00596 6.7e-57 S Protein of unknown function (DUF454)
HKLABNOI_00597 1.3e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HKLABNOI_00598 1.3e-145 yidA S hydrolases of the HAD superfamily
HKLABNOI_00599 4.1e-145 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
HKLABNOI_00600 4.5e-67 ywiB S Domain of unknown function (DUF1934)
HKLABNOI_00601 0.0 pacL 3.6.3.8 P cation transport ATPase
HKLABNOI_00602 4.2e-130 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HKLABNOI_00603 1.3e-151 yjjH S Calcineurin-like phosphoesterase
HKLABNOI_00604 3.5e-205 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKLABNOI_00605 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKLABNOI_00606 5.5e-124 ftsE D cell division ATP-binding protein FtsE
HKLABNOI_00607 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HKLABNOI_00608 4.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HKLABNOI_00609 2.8e-176 yubA S permease
HKLABNOI_00610 3.3e-220 G COG0457 FOG TPR repeat
HKLABNOI_00611 1.6e-94 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HKLABNOI_00612 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HKLABNOI_00613 2e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HKLABNOI_00614 9.6e-86 ebsA S Family of unknown function (DUF5322)
HKLABNOI_00615 9.4e-17 M LysM domain
HKLABNOI_00616 6.2e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HKLABNOI_00617 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKLABNOI_00618 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HKLABNOI_00619 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKLABNOI_00620 5e-76 XK27_03610 K Gnat family
HKLABNOI_00621 1.4e-87 yybC
HKLABNOI_00622 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HKLABNOI_00623 4.1e-267 pepV 3.5.1.18 E Dipeptidase
HKLABNOI_00624 7.4e-106 ung2 3.2.2.27 L Uracil-DNA glycosylase
HKLABNOI_00625 7.2e-226 V Glucan-binding protein C
HKLABNOI_00626 5.7e-253 V Glucan-binding protein C
HKLABNOI_00627 4.7e-120 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKLABNOI_00628 6.1e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKLABNOI_00629 1.4e-93 S Protein of unknown function (DUF1697)
HKLABNOI_00630 3.4e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HKLABNOI_00631 1.2e-172 clcA_2 P Chloride transporter, ClC family
HKLABNOI_00632 4.3e-132 yfeJ 6.3.5.2 F glutamine amidotransferase
HKLABNOI_00633 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HKLABNOI_00634 1.2e-248 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HKLABNOI_00635 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HKLABNOI_00636 3.5e-110 cps4C M biosynthesis protein
HKLABNOI_00637 2e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
HKLABNOI_00638 2.7e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HKLABNOI_00639 4.8e-221 rgpAc GT4 M group 1 family protein
HKLABNOI_00640 6.3e-210 wcoF M Glycosyltransferase, group 1 family protein
HKLABNOI_00641 1.5e-120 Z012_10770 M Domain of unknown function (DUF1919)
HKLABNOI_00642 1.7e-171 M Glycosyltransferase, group 2 family protein
HKLABNOI_00643 1.3e-155 M Glycosyltransferase like family 2
HKLABNOI_00644 1.3e-173
HKLABNOI_00645 5.7e-245 epsU S Polysaccharide biosynthesis protein
HKLABNOI_00646 5.3e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
HKLABNOI_00647 2.7e-172 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
HKLABNOI_00648 4.1e-187 wbbI M transferase activity, transferring glycosyl groups
HKLABNOI_00650 4.9e-31 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HKLABNOI_00651 2.7e-31 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HKLABNOI_00652 3.3e-22 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
HKLABNOI_00653 1.6e-108 pgm G Belongs to the phosphoglycerate mutase family
HKLABNOI_00654 3.7e-108 G Belongs to the phosphoglycerate mutase family
HKLABNOI_00655 3.2e-104 G Belongs to the phosphoglycerate mutase family
HKLABNOI_00656 2e-195 S hmm pf01594
HKLABNOI_00657 2e-282 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLABNOI_00658 4.1e-38 S granule-associated protein
HKLABNOI_00659 5.2e-279 S unusual protein kinase
HKLABNOI_00660 7.2e-99 estA E Lysophospholipase L1 and related esterases
HKLABNOI_00661 9e-153 rssA S Phospholipase, patatin family
HKLABNOI_00662 2.6e-247 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HKLABNOI_00663 9.2e-212 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKLABNOI_00664 5.9e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKLABNOI_00665 3.5e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKLABNOI_00666 2.3e-300 S the current gene model (or a revised gene model) may contain a frame shift
HKLABNOI_00667 2.4e-135 S double-stranded DNA endodeoxyribonuclease activity
HKLABNOI_00668 6.8e-303 hsdM 2.1.1.72 V type I restriction-modification system
HKLABNOI_00669 5e-42 K Helix-turn-helix domain
HKLABNOI_00670 9.8e-56 S Phage derived protein Gp49-like (DUF891)
HKLABNOI_00671 2e-166 E Psort location Cytoplasmic, score
HKLABNOI_00672 1.1e-135 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
HKLABNOI_00673 2.4e-91
HKLABNOI_00674 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HKLABNOI_00675 2.9e-134 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLABNOI_00676 2.5e-198 MA20_36090 S Protein of unknown function (DUF2974)
HKLABNOI_00677 1.8e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKLABNOI_00678 4e-153 5.2.1.8 G hydrolase
HKLABNOI_00679 3e-26 P Hemerythrin HHE cation binding domain protein
HKLABNOI_00680 9.3e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
HKLABNOI_00681 3.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKLABNOI_00682 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
HKLABNOI_00684 1.2e-174 S hydrolase
HKLABNOI_00685 8.4e-23
HKLABNOI_00686 1.1e-136 M LysM domain
HKLABNOI_00687 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HKLABNOI_00688 7.6e-08
HKLABNOI_00689 1.6e-11
HKLABNOI_00690 8.1e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HKLABNOI_00691 1.1e-33 XK27_12190 S protein conserved in bacteria
HKLABNOI_00693 1.1e-87 bioY S biotin synthase
HKLABNOI_00694 1.7e-251 yegQ O Peptidase U32
HKLABNOI_00695 1.5e-177 yegQ O Peptidase U32
HKLABNOI_00697 3e-67 ytxH S General stress protein
HKLABNOI_00698 3.1e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKLABNOI_00699 3.2e-144 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKLABNOI_00700 5e-165 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKLABNOI_00701 2.2e-41 pspC KT PspC domain
HKLABNOI_00702 6.7e-83 ydcK S Belongs to the SprT family
HKLABNOI_00703 0.0 yhgF K Transcriptional accessory protein
HKLABNOI_00705 4.2e-156 XK27_03015 S permease
HKLABNOI_00706 1.7e-148 ycgQ S TIGR03943 family
HKLABNOI_00707 9.7e-165 S CRISPR-associated protein Csn2 subfamily St
HKLABNOI_00708 5.1e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKLABNOI_00709 1e-170 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKLABNOI_00710 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKLABNOI_00711 3.7e-275 sulP P Sulfate permease and related transporters (MFS superfamily)
HKLABNOI_00712 2.9e-100
HKLABNOI_00713 2.1e-114 estA E GDSL-like Lipase/Acylhydrolase
HKLABNOI_00714 1.3e-30 S CAAX protease self-immunity
HKLABNOI_00715 2.9e-57 tnpR L Resolvase, N terminal domain
HKLABNOI_00716 3.2e-07
HKLABNOI_00718 2.7e-201 traI 5.99.1.2 L DNA topoisomerase
HKLABNOI_00720 1.2e-27 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKLABNOI_00721 1.8e-59 D Cellulose biosynthesis protein BcsQ
HKLABNOI_00724 2.1e-50 L Psort location Cytoplasmic, score
HKLABNOI_00726 2.3e-11
HKLABNOI_00728 4.5e-134 L MobA MobL family protein
HKLABNOI_00730 6.4e-23
HKLABNOI_00731 1.7e-22 S Cag pathogenicity island, type IV secretory system
HKLABNOI_00732 1.7e-11
HKLABNOI_00733 1.3e-45
HKLABNOI_00735 2.7e-232 U type IV secretory pathway VirB4
HKLABNOI_00736 1.8e-49 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
HKLABNOI_00737 1.8e-90 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKLABNOI_00738 2.5e-10
HKLABNOI_00740 4.9e-149 traK U COG3505 Type IV secretory pathway, VirD4 components
HKLABNOI_00742 7.5e-43
HKLABNOI_00743 3.3e-223 2.7.13.3 T protein histidine kinase activity
HKLABNOI_00744 3.6e-206 hpk9 2.7.13.3 T protein histidine kinase activity
HKLABNOI_00745 1.5e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HKLABNOI_00746 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKLABNOI_00747 5.6e-213 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKLABNOI_00748 0.0 lpdA 1.8.1.4 C Dehydrogenase
HKLABNOI_00749 0.0 3.5.1.28 NU amidase activity
HKLABNOI_00750 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
HKLABNOI_00751 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HKLABNOI_00752 8.4e-146 ycdO P periplasmic lipoprotein involved in iron transport
HKLABNOI_00753 1.9e-228 ycdB P peroxidase
HKLABNOI_00754 4.1e-290 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HKLABNOI_00755 3.4e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKLABNOI_00756 2.3e-24 tatA U protein secretion
HKLABNOI_00757 1.1e-211 msmX P Belongs to the ABC transporter superfamily
HKLABNOI_00758 9.8e-152 malG P ABC transporter (Permease
HKLABNOI_00759 9.7e-250 malF P ABC transporter (Permease
HKLABNOI_00760 2.1e-227 malX G ABC transporter
HKLABNOI_00761 1.6e-172 malR K Transcriptional regulator
HKLABNOI_00762 0.0 malQ 2.4.1.1, 2.4.1.25 GH77,GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKLABNOI_00763 6.3e-37
HKLABNOI_00764 3e-184 lplA 6.3.1.20 H Lipoate-protein ligase
HKLABNOI_00765 1.3e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HKLABNOI_00766 0.0 pepN 3.4.11.2 E aminopeptidase
HKLABNOI_00767 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
HKLABNOI_00768 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKLABNOI_00769 3.4e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKLABNOI_00770 9.1e-156 pstA P phosphate transport system permease
HKLABNOI_00771 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HKLABNOI_00772 4.5e-155 pstS P phosphate
HKLABNOI_00773 1.5e-244 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HKLABNOI_00774 3.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HKLABNOI_00775 1e-44 yktA S Belongs to the UPF0223 family
HKLABNOI_00776 2.1e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKLABNOI_00777 8.7e-170 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HKLABNOI_00778 5.5e-153 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKLABNOI_00779 1.6e-233 XK27_04775 S hemerythrin HHE cation binding domain
HKLABNOI_00780 4.7e-35 M1-755 P Hemerythrin HHE cation binding domain protein
HKLABNOI_00781 2.1e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HKLABNOI_00782 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKLABNOI_00783 2.6e-135 S haloacid dehalogenase-like hydrolase
HKLABNOI_00784 2.9e-227 metY 2.5.1.49 E o-acetylhomoserine
HKLABNOI_00785 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HKLABNOI_00786 3.8e-238 agcS E (Alanine) symporter
HKLABNOI_00787 9.5e-245 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKLABNOI_00788 5.6e-175 bglC K Transcriptional regulator
HKLABNOI_00789 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HKLABNOI_00790 6.4e-82 yecS P ABC transporter (Permease
HKLABNOI_00791 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
HKLABNOI_00792 4.5e-237 nylA 3.5.1.4 J Belongs to the amidase family
HKLABNOI_00793 6.3e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKLABNOI_00794 1.3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKLABNOI_00795 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKLABNOI_00796 2.2e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HKLABNOI_00797 8.8e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HKLABNOI_00798 4.4e-133 S TraX protein
HKLABNOI_00799 1.1e-306 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HKLABNOI_00800 6.2e-261 S Psort location CytoplasmicMembrane, score
HKLABNOI_00801 1.2e-231 dinF V Mate efflux family protein
HKLABNOI_00802 4.4e-180 yclQ P ABC-type enterochelin transport system, periplasmic component
HKLABNOI_00803 2e-149 S von Willebrand factor (vWF) type A domain
HKLABNOI_00804 0.0 V Type III restriction enzyme, res subunit
HKLABNOI_00805 5.8e-112 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HKLABNOI_00806 4.2e-133 2.4.2.3 F Phosphorylase superfamily
HKLABNOI_00807 0.0 copA 3.6.3.54 P P-type ATPase
HKLABNOI_00808 3.1e-65 silP 1.9.3.1, 3.6.3.54 S cog cog4633
HKLABNOI_00809 2.8e-64 copY K Copper transport repressor, CopY TcrY family
HKLABNOI_00810 2.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKLABNOI_00811 3.4e-14 rpmH J Ribosomal protein L34
HKLABNOI_00812 1e-96 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HKLABNOI_00813 2.2e-97 K Transcriptional regulator
HKLABNOI_00814 1.4e-168 jag S RNA-binding protein
HKLABNOI_00815 1.7e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKLABNOI_00816 3.5e-52 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKLABNOI_00817 1.6e-263 argH 4.3.2.1 E Argininosuccinate lyase
HKLABNOI_00818 1.1e-228 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKLABNOI_00819 7.2e-130 fasA KT Response regulator of the LytR AlgR family
HKLABNOI_00820 1.2e-223 fasC 2.7.13.3 T protein histidine kinase activity
HKLABNOI_00821 4.2e-210 hpk9 2.7.13.3 T protein histidine kinase activity
HKLABNOI_00822 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
HKLABNOI_00823 4.8e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HKLABNOI_00824 1e-281 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKLABNOI_00825 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HKLABNOI_00826 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKLABNOI_00827 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKLABNOI_00828 1.2e-50 S Protein of unknown function (DUF3397)
HKLABNOI_00829 1e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HKLABNOI_00830 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
HKLABNOI_00831 9.9e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKLABNOI_00832 2.3e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
HKLABNOI_00833 7e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HKLABNOI_00834 2.4e-107 XK27_09620 S FMN reductase (NADPH) activity
HKLABNOI_00835 3.9e-229 XK27_09615 C reductase
HKLABNOI_00836 1.2e-138 fnt P Formate nitrite transporter
HKLABNOI_00837 6.7e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
HKLABNOI_00838 1.3e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HKLABNOI_00839 3.5e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKLABNOI_00840 3.5e-115 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HKLABNOI_00841 1.7e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKLABNOI_00842 6.7e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKLABNOI_00843 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKLABNOI_00844 3.5e-140 S HAD hydrolase, family IA, variant
HKLABNOI_00845 6e-157 rrmA 2.1.1.187 Q methyltransferase
HKLABNOI_00849 5.6e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKLABNOI_00850 1.5e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKLABNOI_00851 4.7e-120 S CAAX protease self-immunity
HKLABNOI_00852 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKLABNOI_00853 9e-10 S NTF2 fold immunity protein
HKLABNOI_00854 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKLABNOI_00855 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
HKLABNOI_00856 1.3e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HKLABNOI_00857 4.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKLABNOI_00858 4e-100 S CAAX amino terminal protease family protein
HKLABNOI_00860 3.2e-105 V CAAX protease self-immunity
HKLABNOI_00861 1.5e-26 lanR K sequence-specific DNA binding
HKLABNOI_00862 7.5e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKLABNOI_00863 7.2e-175 ytxK 2.1.1.72 L DNA methylase
HKLABNOI_00864 1.5e-12 comGF U Putative Competence protein ComGF
HKLABNOI_00865 2e-71 comGF U Competence protein ComGF
HKLABNOI_00866 5.3e-15 NU Type II secretory pathway pseudopilin
HKLABNOI_00867 8.4e-70 cglD NU Competence protein
HKLABNOI_00868 2.2e-43 comGC U Required for transformation and DNA binding
HKLABNOI_00869 9.7e-144 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKLABNOI_00870 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKLABNOI_00871 5e-68 S cog cog4699
HKLABNOI_00872 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLABNOI_00873 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLABNOI_00874 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKLABNOI_00875 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKLABNOI_00876 1.4e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKLABNOI_00877 5e-76 ilvN 2.2.1.6 E Acetolactate synthase
HKLABNOI_00878 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HKLABNOI_00879 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HKLABNOI_00880 9.3e-303 yloV S kinase related to dihydroxyacetone kinase
HKLABNOI_00881 1.4e-57 asp S cog cog1302
HKLABNOI_00882 1.9e-223 norN V Mate efflux family protein
HKLABNOI_00883 1.9e-275 thrC 4.2.3.1 E Threonine synthase
HKLABNOI_00886 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HKLABNOI_00887 0.0 pepO 3.4.24.71 O Peptidase family M13
HKLABNOI_00888 1.8e-181 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HKLABNOI_00889 2.3e-84 treR K trehalose operon
HKLABNOI_00890 3.7e-94 ywlG S Belongs to the UPF0340 family
HKLABNOI_00892 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
HKLABNOI_00894 1.6e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
HKLABNOI_00895 4.4e-62 rplQ J ribosomal protein l17
HKLABNOI_00896 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLABNOI_00897 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKLABNOI_00898 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKLABNOI_00899 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HKLABNOI_00900 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKLABNOI_00901 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKLABNOI_00902 4e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKLABNOI_00903 5.7e-58 rplO J binds to the 23S rRNA
HKLABNOI_00904 1.9e-23 rpmD J ribosomal protein l30
HKLABNOI_00905 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKLABNOI_00906 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKLABNOI_00907 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKLABNOI_00908 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKLABNOI_00909 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKLABNOI_00910 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKLABNOI_00911 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKLABNOI_00912 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKLABNOI_00913 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKLABNOI_00914 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HKLABNOI_00915 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKLABNOI_00916 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKLABNOI_00917 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKLABNOI_00918 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKLABNOI_00919 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKLABNOI_00920 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKLABNOI_00921 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
HKLABNOI_00922 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKLABNOI_00923 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HKLABNOI_00924 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKLABNOI_00925 0.0 XK27_09800 I Acyltransferase
HKLABNOI_00926 4.8e-35 XK27_09805 S MORN repeat protein
HKLABNOI_00927 3.4e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKLABNOI_00928 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKLABNOI_00929 9e-92 adk 2.7.4.3 F topology modulation protein
HKLABNOI_00931 4.8e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HKLABNOI_00932 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HKLABNOI_00933 6.3e-44 yrzL S Belongs to the UPF0297 family
HKLABNOI_00934 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKLABNOI_00935 3.2e-44 yrzB S Belongs to the UPF0473 family
HKLABNOI_00936 1.2e-291 ccs S the current gene model (or a revised gene model) may contain a frame shift
HKLABNOI_00937 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HKLABNOI_00938 7.5e-14
HKLABNOI_00939 3.5e-88 XK27_10930 K acetyltransferase
HKLABNOI_00940 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKLABNOI_00941 2.8e-120 yaaA S Belongs to the UPF0246 family
HKLABNOI_00942 9.3e-167 XK27_01785 S cog cog1284
HKLABNOI_00943 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKLABNOI_00945 3.4e-236 hisS 6.1.1.21 J histidyl-tRNA synthetase
HKLABNOI_00946 1.8e-75 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HKLABNOI_00947 1.9e-23 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HKLABNOI_00948 1e-07 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HKLABNOI_00949 4.7e-218 metE 2.1.1.14 E Methionine synthase
HKLABNOI_00950 3.4e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HKLABNOI_00951 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKLABNOI_00952 0.0 fokIM 2.1.1.113, 2.1.1.72 L PFAM DNA methylase N-4 N-6
HKLABNOI_00953 4.5e-266 mrr V Restriction endonuclease
HKLABNOI_00955 1.6e-31 S Protein of unknown function (DUF2971)
HKLABNOI_00956 3e-109 K Peptidase S24-like protein
HKLABNOI_00957 9.8e-131 E IrrE N-terminal-like domain
HKLABNOI_00960 9.5e-45 K Bacteriophage CI repressor helix-turn-helix domain
HKLABNOI_00961 1.3e-42
HKLABNOI_00962 2.3e-73
HKLABNOI_00963 2.2e-275 ydcQ D Ftsk spoiiie family protein
HKLABNOI_00964 4.1e-223 K Replication initiation factor
HKLABNOI_00965 1.3e-32
HKLABNOI_00966 3e-88
HKLABNOI_00967 9.2e-157 S Conjugative transposon protein TcpC
HKLABNOI_00968 3.2e-33
HKLABNOI_00969 6.7e-69 S TcpE family
HKLABNOI_00970 0.0 yddE S AAA-like domain
HKLABNOI_00971 2.1e-250
HKLABNOI_00972 5.7e-30
HKLABNOI_00973 4.8e-170 isp2 S pathogenesis
HKLABNOI_00974 6.1e-36 S MerR HTH family regulatory protein
HKLABNOI_00975 4.9e-219 sip L Belongs to the 'phage' integrase family
HKLABNOI_00976 1.5e-07
HKLABNOI_00979 4.5e-114 nudL L hydrolase
HKLABNOI_00980 5.5e-50 K transcriptional regulator, PadR family
HKLABNOI_00981 8.1e-60 XK27_06920 S Protein of unknown function (DUF1700)
HKLABNOI_00982 9.4e-102 S Putative adhesin
HKLABNOI_00983 6.8e-158 XK27_06930 V domain protein
HKLABNOI_00984 2.1e-94 XK27_06935 K transcriptional regulator
HKLABNOI_00985 7.7e-53 ypaA M Membrane
HKLABNOI_00986 1.1e-10
HKLABNOI_00987 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKLABNOI_00988 1.8e-47 veg S Biofilm formation stimulator VEG
HKLABNOI_00989 5.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HKLABNOI_00990 2.2e-73 rplI J binds to the 23S rRNA
HKLABNOI_00991 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HKLABNOI_00992 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKLABNOI_00993 1.2e-98 yvbG U UPF0056 membrane protein
HKLABNOI_00994 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKLABNOI_00995 0.0 S Bacterial membrane protein, YfhO
HKLABNOI_00996 4.9e-64 isaA GH23 M Immunodominant staphylococcal antigen A
HKLABNOI_00997 1.9e-61 lytE M LysM domain protein
HKLABNOI_00998 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLABNOI_00999 2.4e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLABNOI_01000 3.5e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLABNOI_01001 2.6e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKLABNOI_01002 2.4e-129 S sequence-specific DNA binding
HKLABNOI_01003 3e-232 ymfH S Peptidase M16
HKLABNOI_01004 5.1e-229 ymfF S Peptidase M16
HKLABNOI_01005 1.4e-57 yaaA S S4 domain protein YaaA
HKLABNOI_01006 3.7e-199 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKLABNOI_01007 8.9e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKLABNOI_01008 2.5e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HKLABNOI_01009 7.1e-153 yvjA S membrane
HKLABNOI_01010 5.1e-306 ybiT S abc transporter atp-binding protein
HKLABNOI_01011 0.0 XK27_10405 S Bacterial membrane protein YfhO
HKLABNOI_01015 9e-119 yoaK S Protein of unknown function (DUF1275)
HKLABNOI_01016 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKLABNOI_01017 3.5e-206 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HKLABNOI_01018 6.5e-134 parB K Belongs to the ParB family
HKLABNOI_01019 2.2e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKLABNOI_01020 4.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKLABNOI_01021 3.2e-29 yyzM S Protein conserved in bacteria
HKLABNOI_01022 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKLABNOI_01023 5.2e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKLABNOI_01024 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKLABNOI_01025 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HKLABNOI_01026 8.7e-60 divIC D Septum formation initiator
HKLABNOI_01028 4.9e-235 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HKLABNOI_01029 7.7e-233 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKLABNOI_01030 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKLABNOI_01031 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKLABNOI_01032 1.5e-16 S Domain of unknown function (DUF3173)
HKLABNOI_01033 2.7e-147 L Phage integrase SAM-like domain
HKLABNOI_01035 1.3e-65 traG U COG3505 Type IV secretory pathway, VirD4 components
HKLABNOI_01036 4.7e-103 XK27_00530 M CHAP domain protein
HKLABNOI_01037 6.8e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
HKLABNOI_01038 2.1e-272 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HKLABNOI_01039 0.0 mdlB V abc transporter atp-binding protein
HKLABNOI_01040 0.0 lmrA V abc transporter atp-binding protein
HKLABNOI_01041 3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKLABNOI_01042 1.5e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKLABNOI_01043 1.9e-210 T signal transduction protein with a C-terminal ATPase domain
HKLABNOI_01044 4e-130 rr02 KT response regulator
HKLABNOI_01045 7.1e-164 V ABC transporter
HKLABNOI_01046 1.5e-119 sagI S ABC-2 type transporter
HKLABNOI_01047 2e-196 yceA S Belongs to the UPF0176 family
HKLABNOI_01048 2.7e-28 XK27_00085 K Transcriptional
HKLABNOI_01049 2.1e-21
HKLABNOI_01050 2.9e-134 deoD_1 2.4.2.3 F Phosphorylase superfamily
HKLABNOI_01051 3.9e-114 S VIT family
HKLABNOI_01052 6.5e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKLABNOI_01053 1.3e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HKLABNOI_01054 4.4e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HKLABNOI_01056 1.7e-132 E Alpha beta hydrolase
HKLABNOI_01057 1.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKLABNOI_01058 3.9e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HKLABNOI_01059 1.7e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HKLABNOI_01060 8.9e-168 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HKLABNOI_01061 1.1e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKLABNOI_01062 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HKLABNOI_01063 2.7e-247 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKLABNOI_01064 9.4e-95 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HKLABNOI_01065 8.7e-22
HKLABNOI_01066 2.9e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKLABNOI_01067 0.0 U protein secretion
HKLABNOI_01068 1.5e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HKLABNOI_01069 1e-243 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HKLABNOI_01071 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKLABNOI_01072 2.1e-158 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKLABNOI_01073 1.2e-191 S Protein of unknown function (DUF3114)
HKLABNOI_01074 8.9e-127 S Belongs to the UPF0255 family
HKLABNOI_01075 5.8e-28 K regulation of RNA biosynthetic process
HKLABNOI_01076 1.2e-28 pspC KT PspC domain protein
HKLABNOI_01077 2.6e-118 yqfA K protein, Hemolysin III
HKLABNOI_01078 5e-78 K hmm pf08876
HKLABNOI_01079 6.6e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HKLABNOI_01080 6.5e-210 mvaS 2.3.3.10 I synthase
HKLABNOI_01081 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKLABNOI_01082 1.3e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKLABNOI_01083 9.7e-22
HKLABNOI_01084 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKLABNOI_01085 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HKLABNOI_01086 1.1e-170 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HKLABNOI_01087 2.2e-30 S Domain of unknown function (DUF1912)
HKLABNOI_01088 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
HKLABNOI_01089 1.1e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKLABNOI_01090 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKLABNOI_01092 4.9e-08
HKLABNOI_01093 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKLABNOI_01094 4.5e-199 ilvE 2.6.1.42 E Aminotransferase
HKLABNOI_01095 4.8e-16 S Protein of unknown function (DUF2969)
HKLABNOI_01098 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
HKLABNOI_01101 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
HKLABNOI_01102 1.9e-116 M Pfam SNARE associated Golgi protein
HKLABNOI_01103 1.4e-226 murN 2.3.2.16 V FemAB family
HKLABNOI_01104 6.2e-174 S oxidoreductase
HKLABNOI_01105 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
HKLABNOI_01106 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HKLABNOI_01107 0.0 clpE O Belongs to the ClpA ClpB family
HKLABNOI_01108 1.8e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKLABNOI_01109 1e-34 ykuJ S protein conserved in bacteria
HKLABNOI_01110 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HKLABNOI_01111 3.2e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
HKLABNOI_01112 1.6e-77 feoA P FeoA domain protein
HKLABNOI_01113 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HKLABNOI_01114 6.6e-08
HKLABNOI_01115 8e-148 I Alpha/beta hydrolase family
HKLABNOI_01116 1.1e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKLABNOI_01117 1.7e-143 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKLABNOI_01118 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HKLABNOI_01119 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKLABNOI_01120 3.9e-39 licT K antiterminator
HKLABNOI_01121 4.5e-80 licT K antiterminator
HKLABNOI_01122 8.6e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKLABNOI_01123 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HKLABNOI_01124 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKLABNOI_01125 7.4e-144 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKLABNOI_01126 4e-91 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKLABNOI_01127 2.7e-222 mdtG EGP Major facilitator Superfamily
HKLABNOI_01128 2e-33 secG U Preprotein translocase subunit SecG
HKLABNOI_01129 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKLABNOI_01130 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKLABNOI_01131 1.5e-274 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKLABNOI_01132 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HKLABNOI_01133 8.4e-196 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HKLABNOI_01134 3.2e-181 ccpA K Catabolite control protein A
HKLABNOI_01135 1.3e-193 yyaQ S YjbR
HKLABNOI_01136 5.3e-193 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HKLABNOI_01137 4.5e-74 yueI S Protein of unknown function (DUF1694)
HKLABNOI_01138 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKLABNOI_01139 4.6e-25 WQ51_00785
HKLABNOI_01140 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKLABNOI_01141 1.8e-215 ywbD 2.1.1.191 J Methyltransferase
HKLABNOI_01142 1.9e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKLABNOI_01143 1.4e-153 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKLABNOI_01144 5.4e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKLABNOI_01145 6.4e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKLABNOI_01146 1.3e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HKLABNOI_01147 1.6e-52 yheA S Belongs to the UPF0342 family
HKLABNOI_01148 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HKLABNOI_01149 1.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKLABNOI_01150 2.1e-77 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKLABNOI_01151 5.1e-153 pheA 4.2.1.51 E Prephenate dehydratase
HKLABNOI_01152 5.6e-248 msrR K Transcriptional regulator
HKLABNOI_01153 5.5e-151 ydiA P C4-dicarboxylate transporter malic acid transport
HKLABNOI_01154 5e-201 I acyl-CoA dehydrogenase
HKLABNOI_01155 2e-97 mip S hydroperoxide reductase activity
HKLABNOI_01156 2.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKLABNOI_01157 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
HKLABNOI_01158 2.4e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
HKLABNOI_01159 1.6e-61 smtB K Transcriptional regulator
HKLABNOI_01160 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HKLABNOI_01161 4.3e-22
HKLABNOI_01162 2e-217 EGP Transmembrane secretion effector
HKLABNOI_01163 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
HKLABNOI_01164 1.1e-49
HKLABNOI_01165 8.7e-60
HKLABNOI_01166 5.9e-55
HKLABNOI_01167 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLABNOI_01168 5.7e-112 K Bacterial regulatory proteins, tetR family
HKLABNOI_01169 2e-116 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKLABNOI_01170 3.3e-127 bcrA V abc transporter atp-binding protein
HKLABNOI_01171 8.5e-288 V ABC transporter transmembrane region
HKLABNOI_01172 1.7e-12
HKLABNOI_01173 1.4e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKLABNOI_01174 1.7e-131 S Domain of unknown function (DUF4336)
HKLABNOI_01175 7e-204 yeaN P transporter
HKLABNOI_01176 5.6e-147 yitS S EDD domain protein, DegV family
HKLABNOI_01177 5.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
HKLABNOI_01178 6.6e-99 ypgQ F HD superfamily hydrolase
HKLABNOI_01179 5.2e-129 S CAAX amino terminal protease family
HKLABNOI_01180 1.7e-108 cutC P Participates in the control of copper homeostasis
HKLABNOI_01182 9.2e-21 S Domain of unknown function (DUF4767)
HKLABNOI_01183 4.1e-150 S Domain of unknown function (DUF4300)
HKLABNOI_01184 3.7e-118 V CAAX protease self-immunity
HKLABNOI_01185 3e-150 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLABNOI_01186 2.2e-134 fecE 3.6.3.34 HP ABC transporter
HKLABNOI_01187 2.5e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HKLABNOI_01188 6.5e-125 ybbA S Putative esterase
HKLABNOI_01189 1.1e-118 yegS 2.7.1.107 I Diacylglycerol kinase
HKLABNOI_01190 2.8e-172 S Domain of unknown function (DUF389)
HKLABNOI_01191 5.5e-31 S Membrane
HKLABNOI_01192 7.8e-10 S CsbD-like
HKLABNOI_01193 2.1e-172 pdhD 1.8.1.4 C Dehydrogenase
HKLABNOI_01194 9e-166 acoA C Acetoin dehydrogenase E1 component subunit alpha
HKLABNOI_01195 1.3e-174 acoB C dehydrogenase E1 component
HKLABNOI_01196 1.1e-143 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKLABNOI_01197 1.1e-80 Q Methyltransferase domain
HKLABNOI_01198 1e-62 K TetR family transcriptional regulator
HKLABNOI_01199 7.9e-46
HKLABNOI_01200 1e-128 V CAAX protease self-immunity
HKLABNOI_01201 6.8e-11
HKLABNOI_01202 2.2e-19 S Bacterial lipoprotein
HKLABNOI_01203 5.1e-58 S Protein of unknown function (DUF1722)
HKLABNOI_01204 1.1e-64 yqeB S Pyrimidine dimer DNA glycosylase
HKLABNOI_01206 5.2e-49
HKLABNOI_01207 4.8e-54 S CAAX protease self-immunity
HKLABNOI_01208 4.7e-67 GnaT 2.5.1.16 K acetyltransferase
HKLABNOI_01209 3.4e-21 Q Methyltransferase domain
HKLABNOI_01210 3.1e-136 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLABNOI_01211 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKLABNOI_01212 1.5e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HKLABNOI_01213 6.6e-221 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKLABNOI_01214 9.9e-229 rodA D Belongs to the SEDS family
HKLABNOI_01215 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HKLABNOI_01216 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HKLABNOI_01217 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HKLABNOI_01218 1.2e-180 XK27_08075 M glycosyl transferase family 2
HKLABNOI_01219 4.7e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
HKLABNOI_01220 2e-143 P molecular chaperone
HKLABNOI_01221 5.8e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
HKLABNOI_01223 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HKLABNOI_01224 1.4e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKLABNOI_01225 6.2e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKLABNOI_01226 2.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKLABNOI_01227 2.6e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKLABNOI_01228 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HKLABNOI_01229 3.2e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKLABNOI_01230 1e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKLABNOI_01231 4.8e-182 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKLABNOI_01232 1.8e-190 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKLABNOI_01233 2.1e-59 XK27_08085
HKLABNOI_01234 1.4e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HKLABNOI_01235 2.8e-134 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HKLABNOI_01236 6e-117 ylfI S tigr01906
HKLABNOI_01237 6.7e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKLABNOI_01238 1.4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
HKLABNOI_01239 1.4e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
HKLABNOI_01240 8.4e-30 KT response to antibiotic
HKLABNOI_01242 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKLABNOI_01243 6.4e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKLABNOI_01244 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKLABNOI_01245 5.8e-255 S phospholipase Carboxylesterase
HKLABNOI_01246 1.3e-193 yurR 1.4.5.1 E oxidoreductase
HKLABNOI_01247 1.1e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
HKLABNOI_01248 1.3e-142 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKLABNOI_01249 3.7e-120 trmK 2.1.1.217 S SAM-dependent methyltransferase
HKLABNOI_01250 1.8e-66 gtrA S GtrA-like protein
HKLABNOI_01251 5.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKLABNOI_01252 3.2e-162 ybbR S Protein conserved in bacteria
HKLABNOI_01253 1.4e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKLABNOI_01254 9.9e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HKLABNOI_01255 6.2e-148 cobQ S glutamine amidotransferase
HKLABNOI_01256 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKLABNOI_01257 3.3e-132 pip 1.11.1.10 S Alpha beta hydrolase
HKLABNOI_01258 4.6e-10
HKLABNOI_01259 1.6e-39 MA20_06245 S yiaA/B two helix domain
HKLABNOI_01260 0.0 uup S abc transporter atp-binding protein
HKLABNOI_01261 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HKLABNOI_01262 6e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
HKLABNOI_01263 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
HKLABNOI_01264 2.7e-153 XK27_05675 S Esterase
HKLABNOI_01265 3.9e-161 XK27_05670 S Putative esterase
HKLABNOI_01266 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HKLABNOI_01267 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKLABNOI_01268 5.1e-38 ptsH G phosphocarrier protein Hpr
HKLABNOI_01269 2.2e-218 icd 1.1.1.42 C Isocitrate dehydrogenase
HKLABNOI_01270 2.4e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
HKLABNOI_01271 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HKLABNOI_01272 6.5e-34 nrdH O Glutaredoxin
HKLABNOI_01273 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLABNOI_01274 4.2e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLABNOI_01275 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKLABNOI_01276 1.9e-137 divIVA D Cell division initiation protein
HKLABNOI_01277 2.9e-137 ylmH S conserved protein, contains S4-like domain
HKLABNOI_01278 1.7e-30 yggT D integral membrane protein
HKLABNOI_01279 1e-89 sepF D cell septum assembly
HKLABNOI_01280 2.8e-120 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKLABNOI_01281 4.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKLABNOI_01282 3.5e-223 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKLABNOI_01283 6.7e-135 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKLABNOI_01284 3.1e-198 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKLABNOI_01285 2e-247 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKLABNOI_01287 0.0 typA T GTP-binding protein TypA
HKLABNOI_01288 1.1e-175 glk 2.7.1.2 G Glucokinase
HKLABNOI_01289 4.2e-27 yqgQ S protein conserved in bacteria
HKLABNOI_01290 3.8e-78 perR P Belongs to the Fur family
HKLABNOI_01291 9e-79 dps P Belongs to the Dps family
HKLABNOI_01292 8.1e-101 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HKLABNOI_01293 1.3e-164 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HKLABNOI_01294 2.7e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HKLABNOI_01295 3e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
HKLABNOI_01296 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HKLABNOI_01297 8.1e-64 S Domain of unknown function (DUF4430)
HKLABNOI_01298 4.7e-74 S Psort location CytoplasmicMembrane, score
HKLABNOI_01299 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
HKLABNOI_01300 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
HKLABNOI_01301 9.5e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
HKLABNOI_01302 1.4e-116 sirR K iron dependent repressor
HKLABNOI_01303 1.3e-133 htpX O Belongs to the peptidase M48B family
HKLABNOI_01304 7.7e-92 lemA S LemA family
HKLABNOI_01305 1.5e-175 spd F DNA RNA non-specific endonuclease
HKLABNOI_01306 2.4e-34 2.4.1.21 GT5 M Right handed beta helix region
HKLABNOI_01307 6e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HKLABNOI_01308 3.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKLABNOI_01309 0.0 dnaE 2.7.7.7 L DNA polymerase
HKLABNOI_01310 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKLABNOI_01311 2.8e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKLABNOI_01312 2.5e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKLABNOI_01313 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKLABNOI_01314 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKLABNOI_01315 1.5e-177 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HKLABNOI_01317 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKLABNOI_01318 3.4e-95 ypmS S Protein conserved in bacteria
HKLABNOI_01319 1.2e-155 ypmR E COG2755 Lysophospholipase L1 and related esterases
HKLABNOI_01320 1.2e-144 DegV S DegV family
HKLABNOI_01321 1.9e-300 recN L May be involved in recombinational repair of damaged DNA
HKLABNOI_01322 2.8e-73 argR K Regulates arginine biosynthesis genes
HKLABNOI_01323 4.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HKLABNOI_01324 3.4e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKLABNOI_01325 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKLABNOI_01326 1.4e-232 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKLABNOI_01328 2.1e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKLABNOI_01329 6.5e-125 dnaD
HKLABNOI_01330 3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKLABNOI_01331 4.9e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKLABNOI_01332 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HKLABNOI_01334 1.4e-54
HKLABNOI_01335 1.2e-57 S CD20-like family
HKLABNOI_01337 3e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HKLABNOI_01338 2.2e-131 ecsA V abc transporter atp-binding protein
HKLABNOI_01339 1.6e-175 ecsB U Bacterial ABC transporter protein EcsB
HKLABNOI_01340 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
HKLABNOI_01341 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKLABNOI_01343 1.4e-223 ytfP S Flavoprotein
HKLABNOI_01344 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HKLABNOI_01345 9.6e-64 XK27_02560 S cog cog2151
HKLABNOI_01346 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
HKLABNOI_01347 4.9e-105 dnaQ 2.7.7.7 L DNA polymerase III
HKLABNOI_01348 5.2e-125 K transcriptional regulator, MerR family
HKLABNOI_01349 0.0 V ABC transporter (Permease
HKLABNOI_01350 1.9e-124 V abc transporter atp-binding protein
HKLABNOI_01352 8.7e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKLABNOI_01353 2e-46
HKLABNOI_01354 7.1e-44
HKLABNOI_01355 2.4e-79
HKLABNOI_01356 2.6e-93
HKLABNOI_01357 2.1e-108 E IrrE N-terminal-like domain
HKLABNOI_01358 2e-110 K Peptidase S24-like protein
HKLABNOI_01359 1.2e-74
HKLABNOI_01360 1.8e-24 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLABNOI_01361 0.0
HKLABNOI_01362 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
HKLABNOI_01363 1.7e-148 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HKLABNOI_01364 1.4e-19 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HKLABNOI_01365 4.4e-162 T Diguanylate cyclase
HKLABNOI_01366 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKLABNOI_01367 1.1e-21 fruR K transcriptional
HKLABNOI_01368 2e-46
HKLABNOI_01369 0.0 ctpE P E1-E2 ATPase
HKLABNOI_01370 1.4e-57
HKLABNOI_01371 2.9e-39 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
HKLABNOI_01372 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKLABNOI_01373 1.8e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HKLABNOI_01374 2.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKLABNOI_01375 1.6e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HKLABNOI_01376 1e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HKLABNOI_01377 9.9e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKLABNOI_01378 5.1e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKLABNOI_01381 2.7e-73 copY K negative regulation of transcription, DNA-templated
HKLABNOI_01382 0.0 copA 3.6.3.54 P P-type ATPase
HKLABNOI_01383 1.4e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
HKLABNOI_01384 2.5e-34 K Transcriptional regulator C-terminal region
HKLABNOI_01385 2.9e-83 V ABC transporter
HKLABNOI_01386 6.6e-57
HKLABNOI_01387 1.2e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HKLABNOI_01388 1.1e-113 papP P ABC transporter (Permease
HKLABNOI_01389 3e-106 P ABC transporter (Permease
HKLABNOI_01390 3.4e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
HKLABNOI_01391 9.7e-155 cjaA ET ABC transporter substrate-binding protein
HKLABNOI_01395 6.6e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKLABNOI_01396 2.3e-119 ywaF S Integral membrane protein (intg_mem_TP0381)
HKLABNOI_01397 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKLABNOI_01398 7.7e-195 yjbB G Permeases of the major facilitator superfamily
HKLABNOI_01399 6.5e-151 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HKLABNOI_01400 8.1e-97 thiT S Thiamine transporter
HKLABNOI_01401 9.6e-62 yjqA S Bacterial PH domain
HKLABNOI_01402 1.8e-151 corA P CorA-like protein
HKLABNOI_01403 1.7e-253 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKLABNOI_01405 3e-41 yazA L endonuclease containing a URI domain
HKLABNOI_01406 2.6e-127 yabB 2.1.1.223 L Methyltransferase
HKLABNOI_01407 2.5e-148 nodB3 G Polysaccharide deacetylase
HKLABNOI_01408 1.9e-141 plsC 2.3.1.51 I Acyltransferase
HKLABNOI_01409 2.4e-87 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HKLABNOI_01410 0.0 comEC S Competence protein ComEC
HKLABNOI_01411 3.6e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKLABNOI_01412 1.2e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HKLABNOI_01413 5.6e-231 ytoI K transcriptional regulator containing CBS domains
HKLABNOI_01414 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HKLABNOI_01415 5.3e-162 rbn E Belongs to the UPF0761 family
HKLABNOI_01416 1.7e-85 ccl S cog cog4708
HKLABNOI_01417 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKLABNOI_01418 6.2e-185 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKLABNOI_01420 1e-171 yfjR K regulation of single-species biofilm formation
HKLABNOI_01422 4.4e-72 S QueT transporter
HKLABNOI_01423 8.5e-156 xth 3.1.11.2 L exodeoxyribonuclease III
HKLABNOI_01425 2.9e-17 yjdB S Domain of unknown function (DUF4767)
HKLABNOI_01426 2.1e-165 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HKLABNOI_01427 1e-166 O protein import
HKLABNOI_01428 2.2e-123 agrA KT phosphorelay signal transduction system
HKLABNOI_01429 3.9e-211 2.7.13.3 T protein histidine kinase activity
HKLABNOI_01431 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HKLABNOI_01432 1.5e-36 ylqC L Belongs to the UPF0109 family
HKLABNOI_01433 1.2e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKLABNOI_01434 0.0 ydaO E amino acid
HKLABNOI_01435 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
HKLABNOI_01436 2.6e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKLABNOI_01437 3.2e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HKLABNOI_01438 5e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKLABNOI_01439 3.7e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKLABNOI_01440 3.4e-166 murB 1.3.1.98 M cell wall formation
HKLABNOI_01441 2.6e-211 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKLABNOI_01442 1.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
HKLABNOI_01443 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
HKLABNOI_01444 7e-203 potD P spermidine putrescine ABC transporter
HKLABNOI_01445 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
HKLABNOI_01446 2e-70 gloA 4.4.1.5 E Lactoylglutathione lyase
HKLABNOI_01447 7.3e-153 GK ROK family
HKLABNOI_01448 5.1e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKLABNOI_01449 5.3e-101 wecD M Acetyltransferase (GNAT) domain
HKLABNOI_01450 4.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLABNOI_01451 7.8e-72 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HKLABNOI_01452 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
HKLABNOI_01454 5.9e-56 lrgA S Effector of murein hydrolase LrgA
HKLABNOI_01455 1.1e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HKLABNOI_01456 4.6e-97 3.1.3.18 S IA, variant 1
HKLABNOI_01457 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKLABNOI_01458 7.1e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKLABNOI_01459 2.9e-111 serB 3.1.3.3 E phosphoserine phosphatase
HKLABNOI_01460 8.5e-08 N PFAM Uncharacterised protein family UPF0150
HKLABNOI_01461 2.6e-150 EG Permeases of the drug metabolite transporter (DMT) superfamily
HKLABNOI_01463 3.5e-61 ycaO O OsmC-like protein
HKLABNOI_01464 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
HKLABNOI_01465 1.7e-09 O ADP-ribosylglycohydrolase
HKLABNOI_01466 3.9e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKLABNOI_01468 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKLABNOI_01469 1.7e-17 XK27_00735
HKLABNOI_01470 3.9e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HKLABNOI_01471 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HKLABNOI_01472 8.7e-157 S CAAX amino terminal protease family protein
HKLABNOI_01474 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKLABNOI_01475 2.7e-82 mutT 3.6.1.55 F Nudix family
HKLABNOI_01476 2.1e-135 ET ABC transporter
HKLABNOI_01477 4.2e-136 ET Belongs to the bacterial solute-binding protein 3 family
HKLABNOI_01478 2e-205 arcT 2.6.1.1 E Aminotransferase
HKLABNOI_01479 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
HKLABNOI_01480 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HKLABNOI_01481 9.9e-51 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKLABNOI_01482 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKLABNOI_01483 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKLABNOI_01484 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HKLABNOI_01485 8e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HKLABNOI_01486 1e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKLABNOI_01487 5.6e-214 rgpA GT4 M Domain of unknown function (DUF1972)
HKLABNOI_01488 1.5e-172 rgpB GT2 M Glycosyltransferase, group 2 family protein
HKLABNOI_01489 2e-141 rgpC GM Transport permease protein
HKLABNOI_01490 1.8e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKLABNOI_01491 9.6e-181 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKLABNOI_01492 0.0 rgpF M Rhamnan synthesis protein F
HKLABNOI_01493 1.6e-155 rfbJ M Glycosyl transferase family 2
HKLABNOI_01494 6.9e-43 M Psort location CytoplasmicMembrane, score
HKLABNOI_01495 3.6e-168
HKLABNOI_01496 5.8e-118 radC E Belongs to the UPF0758 family
HKLABNOI_01497 2.2e-128 puuD T peptidase C26
HKLABNOI_01498 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKLABNOI_01499 1.8e-59 XK27_04120 S Putative amino acid metabolism
HKLABNOI_01500 2.7e-205 iscS 2.8.1.7 E Cysteine desulfurase
HKLABNOI_01501 8.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKLABNOI_01502 5.4e-101 yjbK S Adenylate cyclase
HKLABNOI_01503 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HKLABNOI_01504 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKLABNOI_01505 3e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HKLABNOI_01506 1e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HKLABNOI_01507 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HKLABNOI_01508 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
HKLABNOI_01509 1.1e-275 amiC P ABC transporter (Permease
HKLABNOI_01510 1.7e-165 amiD P ABC transporter (Permease
HKLABNOI_01511 1.3e-201 oppD P Belongs to the ABC transporter superfamily
HKLABNOI_01512 1e-170 oppF P Belongs to the ABC transporter superfamily
HKLABNOI_01513 1.4e-128 V Psort location CytoplasmicMembrane, score
HKLABNOI_01514 1.8e-119 skfE V abc transporter atp-binding protein
HKLABNOI_01515 2.8e-61 yvoA_1 K Transcriptional
HKLABNOI_01516 2.5e-144 supH S overlaps another CDS with the same product name
HKLABNOI_01517 9.6e-144 XK27_02985 S overlaps another CDS with the same product name
HKLABNOI_01518 3.2e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKLABNOI_01519 5.7e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HKLABNOI_01520 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HKLABNOI_01521 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKLABNOI_01522 4e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKLABNOI_01523 4.7e-241 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKLABNOI_01524 1.5e-135 stp 3.1.3.16 T phosphatase
HKLABNOI_01525 2.6e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
HKLABNOI_01526 2.1e-100 kcsA P Ion transport protein
HKLABNOI_01527 1.9e-116 yvqF S Membrane
HKLABNOI_01528 1.9e-170 vraS 2.7.13.3 T Histidine kinase
HKLABNOI_01529 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKLABNOI_01532 2.2e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKLABNOI_01533 1.2e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HKLABNOI_01534 9.5e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HKLABNOI_01535 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HKLABNOI_01536 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HKLABNOI_01537 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKLABNOI_01538 3.2e-185 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKLABNOI_01539 1.8e-180 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
HKLABNOI_01540 9.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKLABNOI_01541 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKLABNOI_01542 1.8e-101 2.3.1.128 K Acetyltransferase GNAT Family
HKLABNOI_01543 1.8e-281 S Protein of unknown function (DUF3114)
HKLABNOI_01545 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HKLABNOI_01546 5.2e-296 V abc transporter atp-binding protein
HKLABNOI_01547 0.0 V abc transporter atp-binding protein
HKLABNOI_01548 1.7e-186 XK27_10075 S abc transporter atp-binding protein
HKLABNOI_01549 2e-11
HKLABNOI_01550 3.7e-68 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKLABNOI_01552 2.2e-188 phoH T phosphate starvation-inducible protein PhoH
HKLABNOI_01553 5.3e-125 sip M LysM domain protein
HKLABNOI_01554 8.2e-34 yozE S Belongs to the UPF0346 family
HKLABNOI_01555 8.5e-159 cvfB S Protein conserved in bacteria
HKLABNOI_01556 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKLABNOI_01557 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HKLABNOI_01558 2.3e-210 sptS 2.7.13.3 T Histidine kinase
HKLABNOI_01559 5e-114 T response regulator
HKLABNOI_01560 1.7e-108 2.7.6.5 S Region found in RelA / SpoT proteins
HKLABNOI_01561 1.1e-110 K Acetyltransferase (GNAT) family
HKLABNOI_01562 0.0 lmrA2 V abc transporter atp-binding protein
HKLABNOI_01563 1e-310 lmrA1 V abc transporter atp-binding protein
HKLABNOI_01564 1.4e-72 K DNA-binding transcription factor activity
HKLABNOI_01565 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKLABNOI_01566 4.6e-270 S Psort location CytoplasmicMembrane, score
HKLABNOI_01567 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKLABNOI_01568 8e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HKLABNOI_01569 3.7e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HKLABNOI_01570 3.8e-26 U response to pH
HKLABNOI_01571 0.0 yfmR S abc transporter atp-binding protein
HKLABNOI_01572 3.9e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKLABNOI_01573 5.7e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKLABNOI_01574 3.6e-146 XK27_08360 S EDD domain protein, DegV family
HKLABNOI_01575 5e-63 WQ51_03320 S cog cog4835
HKLABNOI_01576 3.2e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKLABNOI_01577 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HKLABNOI_01578 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HKLABNOI_01579 2.3e-15 L Transposase
HKLABNOI_01580 2.3e-36 L transposase activity
HKLABNOI_01581 8.6e-301 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKLABNOI_01582 4.1e-84 ytsP 1.8.4.14 T GAF domain-containing protein
HKLABNOI_01583 2.4e-159 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKLABNOI_01584 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
HKLABNOI_01587 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKLABNOI_01588 2.9e-208 XK27_05110 P Chloride transporter ClC family
HKLABNOI_01589 1.2e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HKLABNOI_01590 8.6e-279 clcA P Chloride transporter, ClC family
HKLABNOI_01591 1.8e-75 fld C Flavodoxin
HKLABNOI_01592 2.2e-18 XK27_08880
HKLABNOI_01593 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
HKLABNOI_01594 3.6e-148 estA CE1 S Esterase
HKLABNOI_01595 6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKLABNOI_01596 8.9e-136 XK27_08845 S abc transporter atp-binding protein
HKLABNOI_01597 4.4e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HKLABNOI_01598 2.4e-176 XK27_08835 S ABC transporter substrate binding protein
HKLABNOI_01599 1.7e-18 S Domain of unknown function (DUF4649)
HKLABNOI_01600 1e-185 Q the current gene model (or a revised gene model) may contain a frame shift
HKLABNOI_01601 0.0 M Putative cell wall binding repeat
HKLABNOI_01602 9e-225 S dextransucrase activity
HKLABNOI_01604 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKLABNOI_01605 5.2e-43 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKLABNOI_01606 6.3e-163 mleP S Sodium Bile acid symporter family
HKLABNOI_01607 1.1e-310 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
HKLABNOI_01608 4.7e-47 K Helix-turn-helix
HKLABNOI_01609 3.3e-118 mleR K malolactic fermentation system
HKLABNOI_01610 2.8e-113 XK27_00785 S CAAX protease self-immunity
HKLABNOI_01611 3.4e-234 EGP Major facilitator Superfamily
HKLABNOI_01612 1e-64 rmaI K Transcriptional regulator, MarR family
HKLABNOI_01613 1.1e-91 maa 2.3.1.79 GK Maltose O-acetyltransferase
HKLABNOI_01614 6.8e-136 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
HKLABNOI_01615 0.0 3.5.1.28 M domain protein
HKLABNOI_01616 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
HKLABNOI_01617 8.6e-22
HKLABNOI_01620 3.2e-114 M Putative cell wall binding repeat
HKLABNOI_01621 0.0 3.6.3.8 P cation transport ATPase
HKLABNOI_01622 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HKLABNOI_01624 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKLABNOI_01625 3.6e-165 metF 1.5.1.20 E reductase
HKLABNOI_01626 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HKLABNOI_01627 2.7e-92 panT S ECF transporter, substrate-specific component
HKLABNOI_01628 3.1e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKLABNOI_01629 7.1e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HKLABNOI_01630 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HKLABNOI_01631 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKLABNOI_01632 9.8e-237 T PhoQ Sensor
HKLABNOI_01633 1e-29 rpsT J Binds directly to 16S ribosomal RNA
HKLABNOI_01634 2.3e-170 coaA 2.7.1.33 F Pantothenic acid kinase
HKLABNOI_01635 2.3e-102 rsmC 2.1.1.172 J Methyltransferase small domain protein
HKLABNOI_01636 3.4e-228 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HKLABNOI_01637 7.9e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKLABNOI_01638 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKLABNOI_01639 1.2e-191 tcsA S membrane
HKLABNOI_01640 2.4e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HKLABNOI_01641 8.6e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
HKLABNOI_01642 1.2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HKLABNOI_01643 1.7e-119 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HKLABNOI_01644 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HKLABNOI_01645 1.1e-81 ypmB S Protein conserved in bacteria
HKLABNOI_01646 3.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HKLABNOI_01647 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HKLABNOI_01648 8.2e-19
HKLABNOI_01649 1.5e-198 pmrB EGP Major facilitator Superfamily
HKLABNOI_01650 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
HKLABNOI_01651 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HKLABNOI_01652 4.3e-82 queD 4.1.2.50, 4.2.3.12 H synthase
HKLABNOI_01653 1.6e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HKLABNOI_01654 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HKLABNOI_01655 5.1e-182 D nuclear chromosome segregation
HKLABNOI_01656 2.9e-134 yejC S cyclic nucleotide-binding protein
HKLABNOI_01657 5.5e-161 rapZ S Displays ATPase and GTPase activities
HKLABNOI_01658 5.3e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HKLABNOI_01659 5.7e-161 whiA K May be required for sporulation
HKLABNOI_01660 1.8e-275 pepD E Dipeptidase
HKLABNOI_01661 1.2e-141 XK27_10720 D peptidase activity
HKLABNOI_01662 2e-283 adcA P Belongs to the bacterial solute-binding protein 9 family
HKLABNOI_01663 2.6e-09
HKLABNOI_01665 4e-168 yeiH S Membrane
HKLABNOI_01666 6.7e-125 mur1 3.4.17.14, 3.5.1.28 NU muramidase
HKLABNOI_01667 2.9e-165 cpsY K Transcriptional regulator
HKLABNOI_01668 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKLABNOI_01669 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
HKLABNOI_01670 3.1e-105 artQ P ABC transporter (Permease
HKLABNOI_01671 2.8e-111 glnQ 3.6.3.21 E abc transporter atp-binding protein
HKLABNOI_01672 9.7e-155 aatB ET ABC transporter substrate-binding protein
HKLABNOI_01673 3.7e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLABNOI_01674 2.9e-50
HKLABNOI_01675 1.3e-44
HKLABNOI_01676 2.1e-188 adhP 1.1.1.1 C alcohol dehydrogenase
HKLABNOI_01677 4e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKLABNOI_01678 5.6e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HKLABNOI_01679 2.2e-125 gntR1 K transcriptional
HKLABNOI_01680 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKLABNOI_01681 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKLABNOI_01682 2.1e-83
HKLABNOI_01683 6e-83 niaR S small molecule binding protein (contains 3H domain)
HKLABNOI_01684 2.4e-127 K DNA-binding helix-turn-helix protein
HKLABNOI_01685 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKLABNOI_01686 3.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKLABNOI_01687 1.2e-152 GK ROK family
HKLABNOI_01688 4.6e-157 dprA LU DNA protecting protein DprA
HKLABNOI_01689 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKLABNOI_01690 1.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
HKLABNOI_01691 7.7e-52 V ABC-2 family transporter protein
HKLABNOI_01693 6.7e-145 S TraX protein
HKLABNOI_01694 2.9e-122 KT Transcriptional regulatory protein, C terminal
HKLABNOI_01695 1.6e-239 T PhoQ Sensor
HKLABNOI_01696 2e-255 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKLABNOI_01697 1.4e-220 XK27_05470 E Methionine synthase
HKLABNOI_01698 9.4e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HKLABNOI_01699 1.1e-44 pspE P Rhodanese-like protein
HKLABNOI_01700 2.4e-136 IQ Acetoin reductase
HKLABNOI_01702 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKLABNOI_01705 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HKLABNOI_01706 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HKLABNOI_01707 4.9e-65 mgrA K Transcriptional regulator, MarR family
HKLABNOI_01708 3.3e-151 C alcohol dehydrogenase
HKLABNOI_01709 4.7e-126 proV E abc transporter atp-binding protein
HKLABNOI_01710 1.6e-264 proWX P ABC transporter
HKLABNOI_01711 4e-134 S Phenazine biosynthesis protein
HKLABNOI_01712 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
HKLABNOI_01713 3.7e-132 cbiQ P cobalt transport
HKLABNOI_01714 3.9e-156 P ATPase activity
HKLABNOI_01715 6.7e-150 cbiO2 P ABC transporter, ATP-binding protein
HKLABNOI_01716 9.2e-62 pnuC H nicotinamide mononucleotide transporter
HKLABNOI_01717 2.8e-12
HKLABNOI_01718 3.7e-35 S Protein of unknown function with HXXEE motif
HKLABNOI_01719 1.3e-102 K Transcriptional regulator, TetR family
HKLABNOI_01720 8.7e-146 czcD P cation diffusion facilitator family transporter
HKLABNOI_01721 3.2e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HKLABNOI_01722 1.2e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HKLABNOI_01723 1.3e-128 mccF V LD-carboxypeptidase
HKLABNOI_01724 3e-298 O MreB/Mbl protein
HKLABNOI_01726 5.8e-146 V Psort location CytoplasmicMembrane, score
HKLABNOI_01729 1.5e-13
HKLABNOI_01730 5.9e-228 dcuS 2.7.13.3 T protein histidine kinase activity
HKLABNOI_01731 8.3e-233 2.7.13.3 T protein histidine kinase activity
HKLABNOI_01732 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HKLABNOI_01733 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HKLABNOI_01734 6.8e-125 S Protein of unknown function (DUF554)
HKLABNOI_01735 1.5e-132 ecsA_2 V abc transporter atp-binding protein
HKLABNOI_01736 3.2e-276 XK27_00765
HKLABNOI_01737 1.3e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKLABNOI_01738 9.3e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKLABNOI_01739 2.3e-58 yhaI J Membrane
HKLABNOI_01740 6e-33 yhaI J Protein of unknown function (DUF805)
HKLABNOI_01741 1.7e-56 yhaI J Protein of unknown function (DUF805)
HKLABNOI_01742 1.4e-47 yhaI J Protein of unknown function (DUF805)
HKLABNOI_01744 3.8e-97
HKLABNOI_01745 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKLABNOI_01746 4e-45 ftsL D cell division protein FtsL
HKLABNOI_01747 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HKLABNOI_01748 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKLABNOI_01749 3.1e-219 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKLABNOI_01751 5e-257 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKLABNOI_01752 5.7e-63 yutD J protein conserved in bacteria
HKLABNOI_01753 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKLABNOI_01754 1.2e-91 XK27_09885 V Glycopeptide antibiotics resistance protein
HKLABNOI_01757 0.0 mdlA V abc transporter atp-binding protein
HKLABNOI_01758 0.0 mdlB V abc transporter atp-binding protein
HKLABNOI_01767 3.1e-44 spiA K sequence-specific DNA binding
HKLABNOI_01768 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKLABNOI_01769 3.6e-157 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HKLABNOI_01770 4.7e-96 V CAAX protease self-immunity
HKLABNOI_01771 4.7e-137 cppA E CppA N-terminal
HKLABNOI_01772 1.3e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HKLABNOI_01774 1.9e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKLABNOI_01775 1.9e-141 cah 4.2.1.1 P carbonic anhydrase
HKLABNOI_01776 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HKLABNOI_01777 1.6e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLABNOI_01778 8e-35
HKLABNOI_01779 5.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HKLABNOI_01780 1.4e-162 yxeN P ABC transporter (Permease
HKLABNOI_01781 5.2e-128 tcyN 3.6.3.21 E abc transporter atp-binding protein
HKLABNOI_01782 5e-10 S Protein of unknown function (DUF4059)
HKLABNOI_01783 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKLABNOI_01784 2.1e-91 rsmD 2.1.1.171 L Methyltransferase
HKLABNOI_01785 5e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKLABNOI_01786 6e-186 ylbL T Belongs to the peptidase S16 family
HKLABNOI_01787 1e-181 yhcC S radical SAM protein
HKLABNOI_01788 9.4e-95 ytqB 2.1.1.176 J (SAM)-dependent
HKLABNOI_01790 0.0 yjcE P NhaP-type Na H and K H antiporters
HKLABNOI_01791 4.6e-25
HKLABNOI_01793 3.9e-142 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HKLABNOI_01794 1.9e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HKLABNOI_01795 8.1e-09 MU outer membrane autotransporter barrel domain protein
HKLABNOI_01796 9.7e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKLABNOI_01798 2.3e-143 L Integrase core domain protein
HKLABNOI_01799 8.9e-119 L Helix-turn-helix domain
HKLABNOI_01800 9e-75 XK27_03180 T universal stress protein
HKLABNOI_01801 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HKLABNOI_01802 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HKLABNOI_01803 6.4e-99 pncA Q isochorismatase
HKLABNOI_01804 3.2e-291 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKLABNOI_01805 2.4e-215 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HKLABNOI_01806 1.3e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
HKLABNOI_01807 4e-192 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HKLABNOI_01808 3.4e-232 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HKLABNOI_01809 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKLABNOI_01810 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKLABNOI_01811 1.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKLABNOI_01812 2.4e-65
HKLABNOI_01813 1.5e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKLABNOI_01814 1.4e-98 yqeG S hydrolase of the HAD superfamily
HKLABNOI_01815 7.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HKLABNOI_01816 7.7e-49 yhbY J RNA-binding protein
HKLABNOI_01817 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKLABNOI_01818 4.6e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HKLABNOI_01819 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKLABNOI_01820 2.9e-139 yqeM Q Methyltransferase domain protein
HKLABNOI_01821 3.4e-197 ylbM S Belongs to the UPF0348 family
HKLABNOI_01822 3.4e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HKLABNOI_01823 1.6e-44 yoeB S Addiction module toxin, Txe YoeB family
HKLABNOI_01825 1.1e-78 hmpT S cog cog4720
HKLABNOI_01826 3.8e-134 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HKLABNOI_01827 3.8e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKLABNOI_01828 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKLABNOI_01829 5e-108 thiJ-2 3.5.1.124 S DJ-1/PfpI family
HKLABNOI_01830 6e-303 dnaK O Heat shock 70 kDa protein
HKLABNOI_01831 5.9e-70 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKLABNOI_01832 4.1e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKLABNOI_01833 6.7e-99 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
HKLABNOI_01834 4.7e-135 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HKLABNOI_01835 5.6e-132 ais G Phosphoglycerate mutase
HKLABNOI_01836 2.8e-241 XK27_08635 S UPF0210 protein
HKLABNOI_01837 8e-39 gcvR T UPF0237 protein
HKLABNOI_01838 4.3e-233 capA M Bacterial capsule synthesis protein
HKLABNOI_01839 2.7e-149 srtB 3.4.22.70 S Sortase family
HKLABNOI_01841 1.5e-29 K Helix-turn-helix domain
HKLABNOI_01842 2e-18
HKLABNOI_01843 5.6e-81 2.3.1.128 J Acetyltransferase GNAT Family
HKLABNOI_01844 1.4e-21 int L DNA integration
HKLABNOI_01845 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HKLABNOI_01846 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKLABNOI_01848 2.2e-151 degV S DegV family
HKLABNOI_01849 6e-91 yacP S RNA-binding protein containing a PIN domain
HKLABNOI_01850 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKLABNOI_01852 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKLABNOI_01853 5.3e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKLABNOI_01854 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
HKLABNOI_01855 2.3e-139 S SseB protein N-terminal domain
HKLABNOI_01856 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKLABNOI_01857 9e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKLABNOI_01858 7.9e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKLABNOI_01859 0.0 clpC O Belongs to the ClpA ClpB family
HKLABNOI_01860 9e-75 ctsR K Belongs to the CtsR family
HKLABNOI_01861 1.3e-81 S Putative small multi-drug export protein
HKLABNOI_01862 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKLABNOI_01863 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
HKLABNOI_01864 4.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
HKLABNOI_01865 3.5e-288 ahpF O alkyl hydroperoxide reductase
HKLABNOI_01867 5.2e-93 S reductase
HKLABNOI_01868 5.7e-71 badR K Transcriptional regulator, marr family
HKLABNOI_01869 1.2e-35 XK27_02060 S Transglycosylase associated protein
HKLABNOI_01870 2.5e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HKLABNOI_01871 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKLABNOI_01876 1.9e-07
HKLABNOI_01879 1.9e-84 2.3.1.128 K acetyltransferase
HKLABNOI_01880 3.7e-254 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HKLABNOI_01881 4.8e-290 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HKLABNOI_01882 8.2e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKLABNOI_01883 4.1e-209 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HKLABNOI_01885 3.4e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKLABNOI_01886 4.3e-258 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKLABNOI_01888 0.0 fruA 2.7.1.202 G phosphotransferase system
HKLABNOI_01889 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKLABNOI_01890 1.4e-112 fruR K transcriptional
HKLABNOI_01891 2.4e-207 rny D Endoribonuclease that initiates mRNA decay
HKLABNOI_01892 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKLABNOI_01893 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HKLABNOI_01894 2.7e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKLABNOI_01895 1.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HKLABNOI_01896 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKLABNOI_01897 1.8e-52 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKLABNOI_01898 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKLABNOI_01899 1.1e-125 IQ reductase
HKLABNOI_01900 7.2e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HKLABNOI_01901 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HKLABNOI_01902 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKLABNOI_01903 3.7e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKLABNOI_01904 5.2e-72 marR K Transcriptional regulator, MarR family
HKLABNOI_01905 4.8e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HKLABNOI_01906 1.2e-114 S HAD hydrolase, family IA, variant 3
HKLABNOI_01907 3.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
HKLABNOI_01908 2e-191 asnA 6.3.1.1 E aspartate--ammonia ligase
HKLABNOI_01909 6.5e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKLABNOI_01910 5.4e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
HKLABNOI_01911 7.8e-102 ygaC J Belongs to the UPF0374 family
HKLABNOI_01912 9.5e-104 S Domain of unknown function (DUF1803)
HKLABNOI_01913 3.3e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
HKLABNOI_01916 0.0 M domain protein
HKLABNOI_01917 5.2e-114 fhaB M Rib/alpha-like repeat
HKLABNOI_01923 4.9e-111 mreC M Involved in formation and maintenance of cell shape
HKLABNOI_01924 4.4e-81 mreD M rod shape-determining protein MreD
HKLABNOI_01925 5.4e-84 usp 3.5.1.28 CBM50 S CHAP domain
HKLABNOI_01926 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKLABNOI_01927 1.8e-215 araT 2.6.1.1 E Aminotransferase
HKLABNOI_01928 3.7e-137 recO L Involved in DNA repair and RecF pathway recombination
HKLABNOI_01929 3.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKLABNOI_01930 1.4e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKLABNOI_01931 3.4e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HKLABNOI_01932 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKLABNOI_01933 5.1e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKLABNOI_01934 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HKLABNOI_01935 9.9e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKLABNOI_01936 3.6e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HKLABNOI_01937 2.3e-156 S CHAP domain
HKLABNOI_01938 6.1e-238 purD 6.3.4.13 F Belongs to the GARS family
HKLABNOI_01939 3.8e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKLABNOI_01940 1.5e-200 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKLABNOI_01941 3.8e-176 1.1.1.169 H Ketopantoate reductase
HKLABNOI_01942 6.6e-34
HKLABNOI_01943 4.7e-134 J Domain of unknown function (DUF4041)
HKLABNOI_01945 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKLABNOI_01946 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HKLABNOI_01947 3.4e-68 argR K Regulates arginine biosynthesis genes
HKLABNOI_01948 1.8e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HKLABNOI_01949 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKLABNOI_01950 1.3e-78 S Protein of unknown function (DUF3021)
HKLABNOI_01951 5.4e-69 K LytTr DNA-binding domain
HKLABNOI_01953 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKLABNOI_01955 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKLABNOI_01956 4.6e-105 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HKLABNOI_01957 4e-229 cinA 3.5.1.42 S Belongs to the CinA family
HKLABNOI_01958 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKLABNOI_01959 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HKLABNOI_01960 1.4e-116 M domain protein
HKLABNOI_01961 6.7e-89 H Methyltransferase
HKLABNOI_01962 5.3e-22 XK27_10050 K Peptidase S24-like
HKLABNOI_01965 1.3e-42
HKLABNOI_01969 2.8e-103 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HKLABNOI_01970 3.2e-89 abiGI K Transcriptional regulator, AbiEi antitoxin
HKLABNOI_01971 8.2e-130 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HKLABNOI_01973 6.8e-54
HKLABNOI_01974 1.8e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLABNOI_01975 3.6e-107
HKLABNOI_01976 1.1e-70 2.7.13.3 T Histidine kinase
HKLABNOI_01977 8.8e-111 K Transcriptional regulatory protein, C terminal
HKLABNOI_01979 4.3e-48 6.3.5.4 E Asparagine synthase
HKLABNOI_01981 5.1e-24 S Transglutaminase-like superfamily
HKLABNOI_01982 3.8e-120 V abc transporter atp-binding protein
HKLABNOI_01983 3e-17
HKLABNOI_01985 4.3e-85 V ABC transporter, ATP-binding protein
HKLABNOI_01986 5.9e-36 K Helix-turn-helix
HKLABNOI_01987 4.8e-39 D LPXTG cell wall anchor motif
HKLABNOI_01989 1.3e-94 amiB 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
HKLABNOI_01991 3.2e-70
HKLABNOI_01994 1.1e-08
HKLABNOI_01996 0.0 XK27_00500 L the current gene model (or a revised gene model) may contain a
HKLABNOI_01997 6.5e-16
HKLABNOI_01999 2.9e-56 S the current gene model (or a revised gene model) may contain a frame shift
HKLABNOI_02000 1.1e-12 S PcfK-like protein
HKLABNOI_02001 4.7e-39 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKLABNOI_02002 1.9e-17
HKLABNOI_02003 1.5e-71 S Region found in RelA / SpoT proteins
HKLABNOI_02004 1.2e-29 dnaG L DNA primase activity
HKLABNOI_02009 0.0 zmpB M signal peptide protein, YSIRK family
HKLABNOI_02010 0.0 GM domain, Protein
HKLABNOI_02011 9.6e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKLABNOI_02012 0.0 sbcC L ATPase involved in DNA repair
HKLABNOI_02013 0.0 M family 8
HKLABNOI_02014 9.5e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HKLABNOI_02015 6.1e-288 asp1 S Accessory Sec system protein Asp1
HKLABNOI_02016 7.8e-288 asp2 3.4.11.5 S Accessory Sec system protein Asp2
HKLABNOI_02017 4.2e-77 asp3 S Accessory Sec system protein Asp3
HKLABNOI_02018 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKLABNOI_02019 1.3e-279 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HKLABNOI_02020 7.9e-244 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HKLABNOI_02021 2.6e-17 S Accessory secretory protein Sec Asp4
HKLABNOI_02022 3.6e-16 S Accessory secretory protein Sec, Asp5
HKLABNOI_02023 5.4e-189 nss M transferase activity, transferring glycosyl groups
HKLABNOI_02024 1.6e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKLABNOI_02025 1.1e-209 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKLABNOI_02026 8.6e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKLABNOI_02027 2.6e-130
HKLABNOI_02029 7.4e-247 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
HKLABNOI_02030 1e-193 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HKLABNOI_02031 1.6e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKLABNOI_02032 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
HKLABNOI_02033 1.1e-153 endA F DNA RNA non-specific endonuclease
HKLABNOI_02034 4.3e-59 tcyB_2 P ABC transporter (permease)
HKLABNOI_02035 4.7e-79 glnQ 3.6.3.21 E abc transporter atp-binding protein
HKLABNOI_02036 1.4e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HKLABNOI_02037 3.2e-80 glnQ 3.6.3.21 E abc transporter atp-binding protein
HKLABNOI_02038 6.6e-148 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HKLABNOI_02039 1.9e-116 gltJ P ABC transporter (Permease
HKLABNOI_02041 2.5e-232 S dextransucrase activity
HKLABNOI_02042 3.5e-280 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HKLABNOI_02043 3.4e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HKLABNOI_02044 0.0 3.2.1.97, 4.2.2.1 GH101,PL8 N Leucine rich repeats (6 copies)
HKLABNOI_02046 8.3e-20 S Ribosomal protein S1-like RNA-binding domain
HKLABNOI_02048 1e-126 U TraM recognition site of TraD and TraG
HKLABNOI_02061 5.6e-08
HKLABNOI_02067 6e-15 L Transposase, IS605 OrfB family
HKLABNOI_02070 1.5e-31 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKLABNOI_02071 1.6e-64 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HKLABNOI_02072 6e-10 S ERF superfamily
HKLABNOI_02077 1.7e-29 radC E Belongs to the UPF0758 family
HKLABNOI_02079 2.2e-09 panZ K Acetyltransferase (GNAT) domain
HKLABNOI_02087 1.1e-44
HKLABNOI_02090 1.7e-130 clpB O C-terminal, D2-small domain, of ClpB protein
HKLABNOI_02092 1.2e-44
HKLABNOI_02093 7.5e-53 I mechanosensitive ion channel activity
HKLABNOI_02094 2.1e-25
HKLABNOI_02096 9.5e-30
HKLABNOI_02097 1e-45 U AAA-like domain
HKLABNOI_02098 7e-25 soj D ATPases involved in chromosome partitioning
HKLABNOI_02100 1.4e-07 L Psort location Cytoplasmic, score 8.96
HKLABNOI_02101 9.2e-83 L COG1943 Transposase and inactivated derivatives
HKLABNOI_02102 1.6e-20 xerS L Belongs to the 'phage' integrase family
HKLABNOI_02103 5.1e-53 spd F DNA/RNA non-specific endonuclease
HKLABNOI_02104 4.5e-32 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
HKLABNOI_02106 1.9e-223 L Transposase
HKLABNOI_02110 1.8e-42 xisC L viral genome integration into host DNA
HKLABNOI_02112 2.7e-14
HKLABNOI_02114 7e-57 U AAA-like domain
HKLABNOI_02115 2.5e-10
HKLABNOI_02128 5.9e-96 M domain protein
HKLABNOI_02129 0.0 M Pilin isopeptide linkage domain protein
HKLABNOI_02131 2.4e-94
HKLABNOI_02132 1.3e-26

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)