ORF_ID e_value Gene_name EC_number CAZy COGs Description
PAMDGHLD_00001 3.2e-62 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PAMDGHLD_00002 7.7e-86 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PAMDGHLD_00003 1.3e-77 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PAMDGHLD_00004 2.6e-57 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PAMDGHLD_00005 1.7e-32 yqfQ S YqfQ-like protein
PAMDGHLD_00006 7.5e-247 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PAMDGHLD_00007 2.2e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PAMDGHLD_00008 9.3e-37 yqfT S Protein of unknown function (DUF2624)
PAMDGHLD_00009 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
PAMDGHLD_00010 1.4e-71 zur P Belongs to the Fur family
PAMDGHLD_00011 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
PAMDGHLD_00012 2.3e-52 yqfX S membrane
PAMDGHLD_00013 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PAMDGHLD_00014 5.3e-47 yqfZ M LysM domain
PAMDGHLD_00015 8.7e-131 yqgB S Protein of unknown function (DUF1189)
PAMDGHLD_00016 8.6e-76 yqgC S protein conserved in bacteria
PAMDGHLD_00017 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
PAMDGHLD_00018 1.7e-227 yqgE EGP Major facilitator superfamily
PAMDGHLD_00019 0.0 pbpA 3.4.16.4 M penicillin-binding protein
PAMDGHLD_00020 1.7e-157 pstS P Phosphate
PAMDGHLD_00021 5.2e-154 pstC P probably responsible for the translocation of the substrate across the membrane
PAMDGHLD_00022 1.8e-156 pstA P Phosphate transport system permease
PAMDGHLD_00023 7.3e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PAMDGHLD_00024 1.1e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PAMDGHLD_00025 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PAMDGHLD_00026 1.2e-50 yqzD
PAMDGHLD_00027 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PAMDGHLD_00028 6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PAMDGHLD_00029 4e-07 yqgO
PAMDGHLD_00030 2.3e-213 nhaC C Na H antiporter
PAMDGHLD_00031 1e-28 yqgQ S Protein conserved in bacteria
PAMDGHLD_00032 1.7e-179 glcK 2.7.1.2 G Glucokinase
PAMDGHLD_00033 1.3e-218 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
PAMDGHLD_00034 4.6e-199 yqgU
PAMDGHLD_00035 6.9e-50 yqgV S Thiamine-binding protein
PAMDGHLD_00036 5.4e-20 yqgW S Protein of unknown function (DUF2759)
PAMDGHLD_00037 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PAMDGHLD_00038 3.1e-37 yqgY S Protein of unknown function (DUF2626)
PAMDGHLD_00039 4.6e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
PAMDGHLD_00041 1.3e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PAMDGHLD_00042 2.4e-237 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PAMDGHLD_00043 1.2e-185 corA P Mg2 transporter protein
PAMDGHLD_00044 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PAMDGHLD_00045 2.4e-184 comGB NU COG1459 Type II secretory pathway, component PulF
PAMDGHLD_00046 8.9e-50 comGC U Required for transformation and DNA binding
PAMDGHLD_00047 6.9e-72 gspH NU Tfp pilus assembly protein FimT
PAMDGHLD_00048 2e-20 comGE
PAMDGHLD_00049 6.4e-76 comGF U Putative Competence protein ComGF
PAMDGHLD_00050 2.6e-59 S ComG operon protein 7
PAMDGHLD_00051 6.8e-26 yqzE S YqzE-like protein
PAMDGHLD_00052 1.4e-53 yqzG S Protein of unknown function (DUF3889)
PAMDGHLD_00053 8e-120 yqxM
PAMDGHLD_00054 8.6e-70 sipW 3.4.21.89 U Signal peptidase
PAMDGHLD_00055 9.6e-141 tasA S Cell division protein FtsN
PAMDGHLD_00056 7.8e-55 sinR K transcriptional
PAMDGHLD_00057 4.4e-22 sinI S Anti-repressor SinI
PAMDGHLD_00058 9.3e-152 yqhG S Bacterial protein YqhG of unknown function
PAMDGHLD_00059 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PAMDGHLD_00060 3e-209 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
PAMDGHLD_00061 3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PAMDGHLD_00062 8.5e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PAMDGHLD_00063 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
PAMDGHLD_00064 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PAMDGHLD_00065 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PAMDGHLD_00066 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
PAMDGHLD_00067 3.4e-62 yqhP
PAMDGHLD_00068 8e-174 yqhQ S Protein of unknown function (DUF1385)
PAMDGHLD_00069 5.4e-87 yqhR S Conserved membrane protein YqhR
PAMDGHLD_00070 9.5e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
PAMDGHLD_00071 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PAMDGHLD_00072 1.8e-36 yqhV S Protein of unknown function (DUF2619)
PAMDGHLD_00073 1.2e-171 spoIIIAA S stage III sporulation protein AA
PAMDGHLD_00074 3.7e-85 spoIIIAB S Stage III sporulation protein
PAMDGHLD_00075 7.6e-29 spoIIIAC S stage III sporulation protein AC
PAMDGHLD_00076 2.5e-41 spoIIIAD S Stage III sporulation protein AD
PAMDGHLD_00077 6.3e-200 spoIIIAE S stage III sporulation protein AE
PAMDGHLD_00078 2.6e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
PAMDGHLD_00079 2.5e-116 spoIIIAG S stage III sporulation protein AG
PAMDGHLD_00080 2.5e-62 spoIIIAH S SpoIIIAH-like protein
PAMDGHLD_00081 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PAMDGHLD_00082 2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PAMDGHLD_00083 8.1e-67 yqhY S protein conserved in bacteria
PAMDGHLD_00084 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PAMDGHLD_00085 2.5e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PAMDGHLD_00086 1.8e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PAMDGHLD_00087 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PAMDGHLD_00088 4.7e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PAMDGHLD_00089 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PAMDGHLD_00090 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
PAMDGHLD_00091 3.9e-78 argR K Regulates arginine biosynthesis genes
PAMDGHLD_00092 2.7e-305 recN L May be involved in recombinational repair of damaged DNA
PAMDGHLD_00093 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
PAMDGHLD_00094 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PAMDGHLD_00095 8.8e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PAMDGHLD_00098 3.5e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PAMDGHLD_00100 1.2e-112 K Protein of unknown function (DUF1232)
PAMDGHLD_00101 1.5e-101 ytaF P Probably functions as a manganese efflux pump
PAMDGHLD_00102 2.5e-17
PAMDGHLD_00103 2.3e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
PAMDGHLD_00104 1.9e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PAMDGHLD_00105 1.3e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
PAMDGHLD_00106 8.2e-154 hbdA 1.1.1.157 I Dehydrogenase
PAMDGHLD_00107 3e-204 mmgC I acyl-CoA dehydrogenase
PAMDGHLD_00108 4.8e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
PAMDGHLD_00109 3.4e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
PAMDGHLD_00110 8.1e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PAMDGHLD_00111 3.2e-34 yqzF S Protein of unknown function (DUF2627)
PAMDGHLD_00112 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
PAMDGHLD_00113 4.3e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
PAMDGHLD_00114 2e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
PAMDGHLD_00115 4.4e-208 buk 2.7.2.7 C Belongs to the acetokinase family
PAMDGHLD_00116 1.6e-266 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PAMDGHLD_00117 1.9e-162 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PAMDGHLD_00118 2.3e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PAMDGHLD_00119 3.6e-190 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PAMDGHLD_00120 1.9e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PAMDGHLD_00121 1e-75 yqiW S Belongs to the UPF0403 family
PAMDGHLD_00122 2.2e-134 artP ET Belongs to the bacterial solute-binding protein 3 family
PAMDGHLD_00123 1.1e-105 artQ E COG0765 ABC-type amino acid transport system, permease component
PAMDGHLD_00124 3.2e-127 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PAMDGHLD_00125 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
PAMDGHLD_00126 8.3e-66 yqjB S protein conserved in bacteria
PAMDGHLD_00128 7.2e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
PAMDGHLD_00129 5.9e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PAMDGHLD_00130 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
PAMDGHLD_00131 2.3e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PAMDGHLD_00132 2.4e-25 yqzJ
PAMDGHLD_00133 5.6e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PAMDGHLD_00134 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PAMDGHLD_00135 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PAMDGHLD_00136 1.1e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PAMDGHLD_00137 2e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PAMDGHLD_00138 4.8e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PAMDGHLD_00139 7.1e-50 S GlpM protein
PAMDGHLD_00140 3.4e-152 K LysR substrate binding domain
PAMDGHLD_00141 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
PAMDGHLD_00142 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PAMDGHLD_00145 3.8e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PAMDGHLD_00146 1.2e-129 IQ reductase
PAMDGHLD_00147 0.0 pksJ Q Polyketide synthase of type I
PAMDGHLD_00148 0.0 1.1.1.320 Q Polyketide synthase of type I
PAMDGHLD_00149 0.0 Q Polyketide synthase of type I
PAMDGHLD_00150 0.0 pksJ Q Polyketide synthase of type I
PAMDGHLD_00151 0.0 pfaA Q Polyketide synthase of type I
PAMDGHLD_00152 0.0 Q Polyketide synthase of type I
PAMDGHLD_00153 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PAMDGHLD_00154 5.8e-219 eryK 1.14.13.154 C Cytochrome P450
PAMDGHLD_00155 1.6e-238 pksG 2.3.3.10 I synthase
PAMDGHLD_00156 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
PAMDGHLD_00157 6.8e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAMDGHLD_00158 6.6e-176 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
PAMDGHLD_00159 4.2e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
PAMDGHLD_00160 2.1e-257 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
PAMDGHLD_00161 5.9e-177 coaA 2.7.1.33 F Pantothenic acid kinase
PAMDGHLD_00162 1.5e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAMDGHLD_00164 4.6e-186 yueF S transporter activity
PAMDGHLD_00166 7.6e-58 S YolD-like protein
PAMDGHLD_00167 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PAMDGHLD_00168 3.3e-88 yqjY K acetyltransferase
PAMDGHLD_00169 7.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
PAMDGHLD_00170 1.6e-174 yqkA K GrpB protein
PAMDGHLD_00171 3.8e-60 yqkB S Belongs to the HesB IscA family
PAMDGHLD_00172 3.2e-39 yqkC S Protein of unknown function (DUF2552)
PAMDGHLD_00173 3.4e-174 yqkD S COG1073 Hydrolases of the alpha beta superfamily
PAMDGHLD_00175 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
PAMDGHLD_00177 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
PAMDGHLD_00178 3.4e-219 yqxK 3.6.4.12 L DNA helicase
PAMDGHLD_00179 1.9e-56 ansR K Transcriptional regulator
PAMDGHLD_00180 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
PAMDGHLD_00181 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
PAMDGHLD_00182 2.7e-239 mleN C Na H antiporter
PAMDGHLD_00183 7.7e-244 mleA 1.1.1.38 C malic enzyme
PAMDGHLD_00184 2.5e-22
PAMDGHLD_00185 2.7e-29 yqkK
PAMDGHLD_00186 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PAMDGHLD_00187 1.9e-80 fur P Belongs to the Fur family
PAMDGHLD_00188 3.7e-37 S Protein of unknown function (DUF4227)
PAMDGHLD_00189 3.7e-165 xerD L recombinase XerD
PAMDGHLD_00190 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PAMDGHLD_00191 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PAMDGHLD_00192 1.1e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
PAMDGHLD_00193 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
PAMDGHLD_00194 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PAMDGHLD_00195 2.6e-135 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAMDGHLD_00196 1.8e-110 spoVAA S Stage V sporulation protein AA
PAMDGHLD_00197 1.3e-78 spoVAC S stage V sporulation protein AC
PAMDGHLD_00198 5e-190 spoVAD I Stage V sporulation protein AD
PAMDGHLD_00199 3.8e-57 spoVAEB S stage V sporulation protein
PAMDGHLD_00200 5.2e-110 spoVAEA S stage V sporulation protein
PAMDGHLD_00201 9.2e-270 spoVAF EG Stage V sporulation protein AF
PAMDGHLD_00202 2.3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PAMDGHLD_00203 1.2e-152 ypuA S Secreted protein
PAMDGHLD_00204 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PAMDGHLD_00205 1.7e-82 ccdC1 O Protein of unknown function (DUF1453)
PAMDGHLD_00206 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PAMDGHLD_00207 1.7e-49 ypuD
PAMDGHLD_00208 1.1e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PAMDGHLD_00209 1.7e-111 ribE 2.5.1.9 H Riboflavin synthase
PAMDGHLD_00210 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PAMDGHLD_00211 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PAMDGHLD_00212 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAMDGHLD_00213 4.6e-91 ypuF S Domain of unknown function (DUF309)
PAMDGHLD_00215 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PAMDGHLD_00216 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PAMDGHLD_00217 3.8e-93 ypuI S Protein of unknown function (DUF3907)
PAMDGHLD_00218 5e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
PAMDGHLD_00219 2e-103 spmA S Spore maturation protein
PAMDGHLD_00220 1.3e-88 spmB S Spore maturation protein
PAMDGHLD_00221 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PAMDGHLD_00222 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PAMDGHLD_00223 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
PAMDGHLD_00224 4.2e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PAMDGHLD_00225 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_00226 0.0 resE 2.7.13.3 T Histidine kinase
PAMDGHLD_00227 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
PAMDGHLD_00228 6.3e-199 rsiX
PAMDGHLD_00229 2.8e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAMDGHLD_00230 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PAMDGHLD_00231 3.6e-41 fer C Ferredoxin
PAMDGHLD_00232 1.5e-197 ypbB 5.1.3.1 S protein conserved in bacteria
PAMDGHLD_00233 6.1e-271 recQ 3.6.4.12 L DNA helicase
PAMDGHLD_00234 9.9e-100 ypbD S metal-dependent membrane protease
PAMDGHLD_00235 3.1e-80 ypbE M Lysin motif
PAMDGHLD_00236 5.7e-85 ypbF S Protein of unknown function (DUF2663)
PAMDGHLD_00237 2.1e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
PAMDGHLD_00238 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PAMDGHLD_00239 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
PAMDGHLD_00240 9e-189 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
PAMDGHLD_00241 1.6e-120 prsW S Involved in the degradation of specific anti-sigma factors
PAMDGHLD_00242 4.2e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
PAMDGHLD_00243 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
PAMDGHLD_00244 1.4e-60 ypfA M Flagellar protein YcgR
PAMDGHLD_00245 1.4e-12 S Family of unknown function (DUF5359)
PAMDGHLD_00246 2.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PAMDGHLD_00247 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
PAMDGHLD_00248 1.7e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PAMDGHLD_00249 4.7e-08 S YpzI-like protein
PAMDGHLD_00250 1.1e-104 yphA
PAMDGHLD_00251 6.1e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PAMDGHLD_00252 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PAMDGHLD_00253 3.3e-16 yphE S Protein of unknown function (DUF2768)
PAMDGHLD_00254 1.6e-134 yphF
PAMDGHLD_00255 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PAMDGHLD_00256 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PAMDGHLD_00257 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
PAMDGHLD_00258 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PAMDGHLD_00259 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PAMDGHLD_00260 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PAMDGHLD_00261 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PAMDGHLD_00262 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PAMDGHLD_00263 2.1e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
PAMDGHLD_00264 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PAMDGHLD_00265 2.1e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PAMDGHLD_00266 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PAMDGHLD_00267 3.6e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PAMDGHLD_00268 3.5e-159 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PAMDGHLD_00269 1.3e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PAMDGHLD_00270 1.3e-114 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
PAMDGHLD_00271 2.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PAMDGHLD_00272 4.7e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PAMDGHLD_00273 4.6e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PAMDGHLD_00274 5.9e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PAMDGHLD_00275 2e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PAMDGHLD_00276 3.5e-233 S COG0457 FOG TPR repeat
PAMDGHLD_00277 2.1e-99 ypiB S Belongs to the UPF0302 family
PAMDGHLD_00278 3.2e-77 ypiF S Protein of unknown function (DUF2487)
PAMDGHLD_00279 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
PAMDGHLD_00280 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
PAMDGHLD_00281 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
PAMDGHLD_00282 4.1e-104 ypjA S membrane
PAMDGHLD_00283 5.1e-142 ypjB S sporulation protein
PAMDGHLD_00284 9.3e-44 oxdC 4.1.1.2 G Oxalate decarboxylase
PAMDGHLD_00285 3.6e-168 oxdC 4.1.1.2 G Oxalate decarboxylase
PAMDGHLD_00286 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
PAMDGHLD_00287 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
PAMDGHLD_00288 2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PAMDGHLD_00289 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
PAMDGHLD_00290 1.3e-131 bshB1 S proteins, LmbE homologs
PAMDGHLD_00291 9.1e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
PAMDGHLD_00292 1.9e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PAMDGHLD_00293 3.7e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PAMDGHLD_00294 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PAMDGHLD_00295 2.5e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PAMDGHLD_00296 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PAMDGHLD_00297 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PAMDGHLD_00298 6.7e-23 ypmA S Protein of unknown function (DUF4264)
PAMDGHLD_00299 4.5e-80 ypmB S protein conserved in bacteria
PAMDGHLD_00300 3.3e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PAMDGHLD_00301 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
PAMDGHLD_00302 3e-130 dnaD L DNA replication protein DnaD
PAMDGHLD_00303 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PAMDGHLD_00304 4.3e-91 ypoC
PAMDGHLD_00305 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PAMDGHLD_00306 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PAMDGHLD_00307 2.2e-187 yppC S Protein of unknown function (DUF2515)
PAMDGHLD_00310 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
PAMDGHLD_00312 2.5e-43 yppG S YppG-like protein
PAMDGHLD_00313 1.7e-72 hspX O Belongs to the small heat shock protein (HSP20) family
PAMDGHLD_00314 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
PAMDGHLD_00315 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PAMDGHLD_00316 7.8e-238 yprB L RNase_H superfamily
PAMDGHLD_00318 9.9e-33 cotD S Inner spore coat protein D
PAMDGHLD_00319 4.8e-99 ypsA S Belongs to the UPF0398 family
PAMDGHLD_00320 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PAMDGHLD_00321 4.2e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PAMDGHLD_00322 6.6e-22 S YpzG-like protein
PAMDGHLD_00324 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
PAMDGHLD_00325 1.3e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PAMDGHLD_00326 5.7e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PAMDGHLD_00327 5.5e-234 pbuX F xanthine
PAMDGHLD_00329 7e-101 yrdC 3.5.1.19 Q Isochorismatase family
PAMDGHLD_00331 6.2e-51 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
PAMDGHLD_00332 1.3e-105 J Acetyltransferase (GNAT) domain
PAMDGHLD_00333 3.5e-205 bcsA Q Naringenin-chalcone synthase
PAMDGHLD_00334 1.2e-88 ypbQ S protein conserved in bacteria
PAMDGHLD_00335 0.0 ypbR S Dynamin family
PAMDGHLD_00336 1.7e-38 ypbS S Protein of unknown function (DUF2533)
PAMDGHLD_00338 1.4e-164 polA 2.7.7.7 L 5'3' exonuclease
PAMDGHLD_00340 4.9e-69 rnhA 3.1.26.4 L Ribonuclease
PAMDGHLD_00341 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PAMDGHLD_00342 2.4e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
PAMDGHLD_00343 1.5e-28 ypeQ S Zinc-finger
PAMDGHLD_00344 6.1e-36 S Protein of unknown function (DUF2564)
PAMDGHLD_00345 9.7e-12 degR
PAMDGHLD_00346 7.9e-31 cspD K Cold-shock protein
PAMDGHLD_00347 5.5e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
PAMDGHLD_00348 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PAMDGHLD_00349 3.2e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PAMDGHLD_00350 7.8e-98 ypgQ S phosphohydrolase
PAMDGHLD_00351 1.5e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
PAMDGHLD_00352 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PAMDGHLD_00353 1e-75 yphP S Belongs to the UPF0403 family
PAMDGHLD_00354 4.4e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
PAMDGHLD_00355 2.7e-114 ypjP S YpjP-like protein
PAMDGHLD_00356 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PAMDGHLD_00357 6.2e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PAMDGHLD_00358 1e-113 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PAMDGHLD_00359 2.7e-109 hlyIII S protein, Hemolysin III
PAMDGHLD_00360 2.6e-175 pspF K Transcriptional regulator
PAMDGHLD_00361 2.4e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PAMDGHLD_00362 2.6e-39 ypmP S Protein of unknown function (DUF2535)
PAMDGHLD_00363 3.3e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PAMDGHLD_00364 2.6e-135 ypmR E GDSL-like Lipase/Acylhydrolase
PAMDGHLD_00365 1.6e-97 ypmS S protein conserved in bacteria
PAMDGHLD_00366 1.4e-66 ypoP K transcriptional
PAMDGHLD_00367 5.9e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PAMDGHLD_00368 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PAMDGHLD_00369 2.6e-103 4.2.1.115 GM Polysaccharide biosynthesis protein
PAMDGHLD_00370 6.9e-306 yokA L Recombinase
PAMDGHLD_00371 3.4e-76 yokF 3.1.31.1 L RNA catabolic process
PAMDGHLD_00372 8.6e-85 G SMI1-KNR4 cell-wall
PAMDGHLD_00373 1.5e-290 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PAMDGHLD_00374 8.3e-52 S SMI1-KNR4 cell-wall
PAMDGHLD_00376 2.9e-158 3.4.24.40 S amine dehydrogenase activity
PAMDGHLD_00378 6.3e-202 S aspartate phosphatase
PAMDGHLD_00379 2.4e-38 yoqH M LysM domain
PAMDGHLD_00384 3e-72 4.2.1.115 GM Polysaccharide biosynthesis protein
PAMDGHLD_00385 1.6e-216 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
PAMDGHLD_00386 1.9e-167 cgeB S Spore maturation protein
PAMDGHLD_00387 4.9e-54 cgeA
PAMDGHLD_00388 1.1e-41 cgeC
PAMDGHLD_00389 8.5e-248 cgeD M maturation of the outermost layer of the spore
PAMDGHLD_00390 8.3e-145 yiiD K acetyltransferase
PAMDGHLD_00392 2.4e-64 yosT L Bacterial transcription activator, effector binding domain
PAMDGHLD_00393 8.9e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAMDGHLD_00394 5.8e-126 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PAMDGHLD_00395 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PAMDGHLD_00396 2.4e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
PAMDGHLD_00397 2.5e-158 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
PAMDGHLD_00398 1.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
PAMDGHLD_00399 4.6e-45 yokU S YokU-like protein, putative antitoxin
PAMDGHLD_00400 4.1e-36 yozE S Belongs to the UPF0346 family
PAMDGHLD_00401 1.7e-125 yodN
PAMDGHLD_00403 6.2e-24 yozD S YozD-like protein
PAMDGHLD_00404 5.8e-101 yodM 3.6.1.27 I Acid phosphatase homologues
PAMDGHLD_00405 3.3e-55 yodL S YodL-like
PAMDGHLD_00407 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
PAMDGHLD_00408 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PAMDGHLD_00409 4.3e-34 yodI
PAMDGHLD_00410 3.7e-128 yodH Q Methyltransferase
PAMDGHLD_00411 2.1e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
PAMDGHLD_00412 2.8e-131 yydK K Transcriptional regulator
PAMDGHLD_00413 6e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PAMDGHLD_00414 8e-282 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
PAMDGHLD_00415 1e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAMDGHLD_00416 1.4e-19 S Protein of unknown function (DUF3311)
PAMDGHLD_00417 2.7e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
PAMDGHLD_00418 3.6e-95 mhqD S Carboxylesterase
PAMDGHLD_00419 4.5e-106 yodC C nitroreductase
PAMDGHLD_00420 1.4e-56 yodB K transcriptional
PAMDGHLD_00421 1.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
PAMDGHLD_00422 5.9e-67 yodA S tautomerase
PAMDGHLD_00424 1.3e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
PAMDGHLD_00425 1.3e-162 rarD S -transporter
PAMDGHLD_00426 4.9e-23
PAMDGHLD_00427 9.7e-61 yojF S Protein of unknown function (DUF1806)
PAMDGHLD_00428 2.5e-126 yojG S deacetylase
PAMDGHLD_00429 2.5e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PAMDGHLD_00430 1.5e-242 norM V Multidrug efflux pump
PAMDGHLD_00432 5.3e-110 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PAMDGHLD_00433 2.5e-217 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
PAMDGHLD_00434 1.4e-223 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PAMDGHLD_00435 8.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PAMDGHLD_00436 2e-163 yojN S ATPase family associated with various cellular activities (AAA)
PAMDGHLD_00437 0.0 yojO P Von Willebrand factor
PAMDGHLD_00438 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PAMDGHLD_00439 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PAMDGHLD_00440 1.2e-140 S Metallo-beta-lactamase superfamily
PAMDGHLD_00441 7.9e-161 yocS S -transporter
PAMDGHLD_00442 8.7e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PAMDGHLD_00443 3.2e-166 sodA 1.15.1.1 P Superoxide dismutase
PAMDGHLD_00444 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
PAMDGHLD_00445 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
PAMDGHLD_00446 1.8e-30 yozC
PAMDGHLD_00448 2.4e-56 yozO S Bacterial PH domain
PAMDGHLD_00449 8.5e-37 yocN
PAMDGHLD_00450 2.1e-42 yozN
PAMDGHLD_00451 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
PAMDGHLD_00452 1.3e-08
PAMDGHLD_00453 7.8e-10 yocL
PAMDGHLD_00454 1.9e-54 dksA T general stress protein
PAMDGHLD_00456 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PAMDGHLD_00457 0.0 recQ 3.6.4.12 L DNA helicase
PAMDGHLD_00458 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
PAMDGHLD_00460 4.6e-185 yocD 3.4.17.13 V peptidase S66
PAMDGHLD_00461 2.5e-94 yocC
PAMDGHLD_00462 2e-138 yocB J Protein required for attachment to host cells
PAMDGHLD_00463 6.9e-90 yozB S membrane
PAMDGHLD_00464 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PAMDGHLD_00465 1.7e-54 czrA K transcriptional
PAMDGHLD_00466 5.5e-92 yobW
PAMDGHLD_00467 2.2e-136 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
PAMDGHLD_00468 7e-93 yobS K Transcriptional regulator
PAMDGHLD_00469 4.8e-131 yobQ K helix_turn_helix, arabinose operon control protein
PAMDGHLD_00470 1.1e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
PAMDGHLD_00471 3.9e-307 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PAMDGHLD_00472 6.2e-55 S SMI1-KNR4 cell-wall
PAMDGHLD_00473 8.1e-42
PAMDGHLD_00474 1.3e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
PAMDGHLD_00476 3.6e-16 yoaF
PAMDGHLD_00477 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAMDGHLD_00478 3.8e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAMDGHLD_00479 5.7e-272 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
PAMDGHLD_00480 3.3e-204 yoaB EGP Major facilitator Superfamily
PAMDGHLD_00481 2.1e-137 yoxB
PAMDGHLD_00482 3.5e-38 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PAMDGHLD_00483 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PAMDGHLD_00484 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PAMDGHLD_00485 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAMDGHLD_00486 7.3e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PAMDGHLD_00487 3.3e-153 gltC K Transcriptional regulator
PAMDGHLD_00488 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
PAMDGHLD_00489 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PAMDGHLD_00490 2.2e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PAMDGHLD_00491 2.6e-155 gltR1 K Transcriptional regulator
PAMDGHLD_00492 3.1e-270 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PAMDGHLD_00493 1.8e-50 ybzH K Helix-turn-helix domain
PAMDGHLD_00494 6.1e-200 ybcL EGP Major facilitator Superfamily
PAMDGHLD_00495 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PAMDGHLD_00496 1.8e-34 yoeD G Helix-turn-helix domain
PAMDGHLD_00497 3.5e-97 L Integrase
PAMDGHLD_00499 1.4e-95 yoeB S IseA DL-endopeptidase inhibitor
PAMDGHLD_00500 4.6e-247 yoeA V MATE efflux family protein
PAMDGHLD_00501 2.6e-188 yoxA 5.1.3.3 G Aldose 1-epimerase
PAMDGHLD_00502 2.2e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
PAMDGHLD_00503 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_00504 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_00505 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_00506 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_00507 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
PAMDGHLD_00508 1.6e-64 yngL S Protein of unknown function (DUF1360)
PAMDGHLD_00509 1.2e-304 yngK T Glycosyl hydrolase-like 10
PAMDGHLD_00510 4.1e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
PAMDGHLD_00511 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PAMDGHLD_00512 1.9e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
PAMDGHLD_00513 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
PAMDGHLD_00514 4.7e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
PAMDGHLD_00515 6.4e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
PAMDGHLD_00516 2.6e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PAMDGHLD_00517 3.2e-104 yngC S SNARE associated Golgi protein
PAMDGHLD_00518 9.1e-113 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PAMDGHLD_00519 3.7e-72 yngA S membrane
PAMDGHLD_00520 9e-144 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
PAMDGHLD_00521 7.4e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
PAMDGHLD_00522 1.1e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PAMDGHLD_00523 2.6e-129 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PAMDGHLD_00524 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PAMDGHLD_00525 8.9e-223 bioI 1.14.14.46 C Cytochrome P450
PAMDGHLD_00526 3.4e-253 yxjC EG COG2610 H gluconate symporter and related permeases
PAMDGHLD_00527 3.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PAMDGHLD_00528 1.2e-120 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PAMDGHLD_00529 2e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PAMDGHLD_00530 4.3e-225 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PAMDGHLD_00531 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_00532 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_00533 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_00534 5.2e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
PAMDGHLD_00535 1.1e-250 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
PAMDGHLD_00536 3.8e-128 T Transcriptional regulatory protein, C terminal
PAMDGHLD_00537 3.2e-232 T PhoQ Sensor
PAMDGHLD_00538 4e-50 S Domain of unknown function (DUF4870)
PAMDGHLD_00539 8.4e-287 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
PAMDGHLD_00540 1.1e-211 S Platelet-activating factor acetylhydrolase, isoform II
PAMDGHLD_00542 5.4e-10 yxlH EGP Major facilitator Superfamily
PAMDGHLD_00543 1.9e-300 yndJ S YndJ-like protein
PAMDGHLD_00544 3.1e-78 yndH S Domain of unknown function (DUF4166)
PAMDGHLD_00545 6.4e-156 yndG S DoxX-like family
PAMDGHLD_00546 1.2e-222 exuT G Sugar (and other) transporter
PAMDGHLD_00547 1.1e-181 kdgR_1 K transcriptional
PAMDGHLD_00548 8.6e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PAMDGHLD_00549 4.4e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
PAMDGHLD_00550 6.8e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
PAMDGHLD_00551 3.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
PAMDGHLD_00552 1.9e-183 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
PAMDGHLD_00553 1.6e-250 agcS E Sodium alanine symporter
PAMDGHLD_00554 5.1e-41 ynfC
PAMDGHLD_00555 1.6e-13
PAMDGHLD_00556 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PAMDGHLD_00557 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PAMDGHLD_00558 1.5e-68 yccU S CoA-binding protein
PAMDGHLD_00559 2.5e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PAMDGHLD_00560 1.3e-50 yneR S Belongs to the HesB IscA family
PAMDGHLD_00561 3.7e-53 yneQ
PAMDGHLD_00562 8.3e-75 yneP S Thioesterase-like superfamily
PAMDGHLD_00563 7.8e-33 tlp S Belongs to the Tlp family
PAMDGHLD_00565 7e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PAMDGHLD_00566 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PAMDGHLD_00567 2.2e-14 sspO S Belongs to the SspO family
PAMDGHLD_00568 3.9e-19 sspP S Belongs to the SspP family
PAMDGHLD_00569 3.2e-62 hspX O Spore coat protein
PAMDGHLD_00570 8.5e-75 yneK S Protein of unknown function (DUF2621)
PAMDGHLD_00571 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
PAMDGHLD_00572 1.4e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
PAMDGHLD_00573 1.3e-125 ccdA O cytochrome c biogenesis protein
PAMDGHLD_00574 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
PAMDGHLD_00575 2.3e-28 yneF S UPF0154 protein
PAMDGHLD_00576 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
PAMDGHLD_00577 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PAMDGHLD_00578 9.8e-33 ynzC S UPF0291 protein
PAMDGHLD_00579 3.5e-112 yneB L resolvase
PAMDGHLD_00580 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PAMDGHLD_00581 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PAMDGHLD_00582 7.8e-12 yoaW
PAMDGHLD_00583 2.4e-72 yndM S Protein of unknown function (DUF2512)
PAMDGHLD_00584 3.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
PAMDGHLD_00585 1.6e-07
PAMDGHLD_00586 8.2e-143 yndL S Replication protein
PAMDGHLD_00587 8.3e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
PAMDGHLD_00588 0.0 yobO M Pectate lyase superfamily protein
PAMDGHLD_00592 2.6e-117 AA10,CBM73 S Pfam:Chitin_bind_3
PAMDGHLD_00593 4.6e-202 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAMDGHLD_00594 1e-107 ynaE S Domain of unknown function (DUF3885)
PAMDGHLD_00595 1.4e-98 J Acetyltransferase (GNAT) domain
PAMDGHLD_00596 1.3e-60 yoaP 3.1.3.18 K YoaP-like
PAMDGHLD_00597 3.9e-74 yoaP 3.1.3.18 K YoaP-like
PAMDGHLD_00599 1.2e-29
PAMDGHLD_00601 3.8e-17
PAMDGHLD_00602 1.2e-69 ccmM S Bacterial transferase hexapeptide (six repeats)
PAMDGHLD_00603 1.4e-184 adhP 1.1.1.1 C alcohol dehydrogenase
PAMDGHLD_00604 6e-55 dinB S DinB family
PAMDGHLD_00605 5.4e-17
PAMDGHLD_00609 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
PAMDGHLD_00610 7.6e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
PAMDGHLD_00611 4.9e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
PAMDGHLD_00612 3.5e-216 xylR GK ROK family
PAMDGHLD_00613 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
PAMDGHLD_00614 3.4e-250 xynT G MFS/sugar transport protein
PAMDGHLD_00615 1.5e-208 mrjp G Major royal jelly protein
PAMDGHLD_00616 1.2e-43 T Histidine kinase
PAMDGHLD_00617 1e-41 S Protein of unknown function (DUF2568)
PAMDGHLD_00619 5.4e-11
PAMDGHLD_00621 9.5e-89
PAMDGHLD_00622 3.1e-21
PAMDGHLD_00623 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
PAMDGHLD_00624 1.6e-67 glnR K transcriptional
PAMDGHLD_00625 5.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PAMDGHLD_00626 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PAMDGHLD_00627 1.3e-176 spoVK O stage V sporulation protein K
PAMDGHLD_00628 4.3e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PAMDGHLD_00629 9e-110 ymaB S MutT family
PAMDGHLD_00630 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAMDGHLD_00631 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAMDGHLD_00632 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
PAMDGHLD_00633 1.8e-20 ymzA
PAMDGHLD_00634 2.1e-42
PAMDGHLD_00635 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PAMDGHLD_00636 2.1e-171 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PAMDGHLD_00637 1.4e-47 ymaF S YmaF family
PAMDGHLD_00639 3.1e-48 ebrA P Small Multidrug Resistance protein
PAMDGHLD_00640 1.7e-52 ebrB P Small Multidrug Resistance protein
PAMDGHLD_00641 2.1e-76 ymaD O redox protein, regulator of disulfide bond formation
PAMDGHLD_00642 1.5e-124 ymaC S Replication protein
PAMDGHLD_00644 4.4e-255 aprX O Belongs to the peptidase S8 family
PAMDGHLD_00645 1.4e-62 ymzB
PAMDGHLD_00646 2.7e-118 yoaK S Membrane
PAMDGHLD_00647 4.9e-78 nucB M Deoxyribonuclease NucA/NucB
PAMDGHLD_00648 1e-229 cypA C Cytochrome P450
PAMDGHLD_00649 0.0 pks13 HQ Beta-ketoacyl synthase
PAMDGHLD_00650 0.0 dhbF IQ polyketide synthase
PAMDGHLD_00651 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
PAMDGHLD_00652 0.0 Q Polyketide synthase of type I
PAMDGHLD_00653 0.0 rhiB IQ polyketide synthase
PAMDGHLD_00654 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
PAMDGHLD_00655 4.5e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
PAMDGHLD_00656 2.8e-243 pksG 2.3.3.10 I synthase
PAMDGHLD_00657 1.3e-35 acpK IQ Phosphopantetheine attachment site
PAMDGHLD_00658 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PAMDGHLD_00659 1.9e-183 pksD Q Acyl transferase domain
PAMDGHLD_00660 1.1e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PAMDGHLD_00661 7.4e-129 pksB 3.1.2.6 S Polyketide biosynthesis
PAMDGHLD_00663 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PAMDGHLD_00664 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PAMDGHLD_00665 1.7e-88 cotE S Spore coat protein
PAMDGHLD_00666 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PAMDGHLD_00667 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PAMDGHLD_00668 2.6e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PAMDGHLD_00669 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
PAMDGHLD_00670 1.2e-36 spoVS S Stage V sporulation protein S
PAMDGHLD_00671 4.9e-153 ymdB S protein conserved in bacteria
PAMDGHLD_00672 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
PAMDGHLD_00673 4.9e-181 pbpX V Beta-lactamase
PAMDGHLD_00674 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PAMDGHLD_00675 1.4e-231 cinA 3.5.1.42 S Belongs to the CinA family
PAMDGHLD_00676 1.1e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PAMDGHLD_00677 4.2e-124 ymfM S protein conserved in bacteria
PAMDGHLD_00678 1e-142 ymfK S Protein of unknown function (DUF3388)
PAMDGHLD_00679 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
PAMDGHLD_00680 3.9e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PAMDGHLD_00681 1.3e-243 ymfH S zinc protease
PAMDGHLD_00682 1.2e-238 ymfF S Peptidase M16
PAMDGHLD_00683 0.0 ydgH S drug exporters of the RND superfamily
PAMDGHLD_00684 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
PAMDGHLD_00685 1.1e-229 ymfD EGP Major facilitator Superfamily
PAMDGHLD_00686 1.8e-133 ymfC K Transcriptional regulator
PAMDGHLD_00687 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PAMDGHLD_00688 8.2e-31 S YlzJ-like protein
PAMDGHLD_00689 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
PAMDGHLD_00690 8.8e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PAMDGHLD_00691 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PAMDGHLD_00692 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
PAMDGHLD_00693 3.4e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PAMDGHLD_00694 4.4e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PAMDGHLD_00695 8.8e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
PAMDGHLD_00696 2.6e-42 ymxH S YlmC YmxH family
PAMDGHLD_00697 5.2e-234 pepR S Belongs to the peptidase M16 family
PAMDGHLD_00698 8.8e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
PAMDGHLD_00699 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PAMDGHLD_00700 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PAMDGHLD_00701 3.5e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PAMDGHLD_00702 8e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PAMDGHLD_00703 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PAMDGHLD_00704 3.9e-44 ylxP S protein conserved in bacteria
PAMDGHLD_00705 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PAMDGHLD_00706 1.8e-47 ylxQ J ribosomal protein
PAMDGHLD_00707 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
PAMDGHLD_00708 5.4e-206 nusA K Participates in both transcription termination and antitermination
PAMDGHLD_00709 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
PAMDGHLD_00710 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PAMDGHLD_00711 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PAMDGHLD_00712 1.5e-233 rasP M zinc metalloprotease
PAMDGHLD_00713 1.2e-213 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PAMDGHLD_00714 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
PAMDGHLD_00715 2.2e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PAMDGHLD_00716 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PAMDGHLD_00717 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PAMDGHLD_00718 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PAMDGHLD_00719 1.4e-130 rpsB J Belongs to the universal ribosomal protein uS2 family
PAMDGHLD_00720 6.9e-54 ylxL
PAMDGHLD_00721 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAMDGHLD_00722 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PAMDGHLD_00723 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PAMDGHLD_00724 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
PAMDGHLD_00725 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
PAMDGHLD_00726 2.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PAMDGHLD_00727 1.6e-155 flhG D Belongs to the ParA family
PAMDGHLD_00728 2.7e-194 flhF N Flagellar biosynthesis regulator FlhF
PAMDGHLD_00729 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PAMDGHLD_00730 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PAMDGHLD_00731 1.2e-130 fliR N Flagellar biosynthetic protein FliR
PAMDGHLD_00732 2e-37 fliQ N Role in flagellar biosynthesis
PAMDGHLD_00733 4.3e-110 fliP N Plays a role in the flagellum-specific transport system
PAMDGHLD_00734 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
PAMDGHLD_00735 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
PAMDGHLD_00736 9e-180 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PAMDGHLD_00737 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PAMDGHLD_00738 5.1e-56 fliL N Controls the rotational direction of flagella during chemotaxis
PAMDGHLD_00739 4e-139 flgG N Flagellar basal body rod
PAMDGHLD_00740 1.4e-72 flgD N Flagellar basal body rod modification protein
PAMDGHLD_00741 1e-203 fliK N Flagellar hook-length control protein
PAMDGHLD_00742 1.3e-47 ylxF S MgtE intracellular N domain
PAMDGHLD_00743 1.7e-70 fliJ N Flagellar biosynthesis chaperone
PAMDGHLD_00744 5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PAMDGHLD_00745 9e-88 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
PAMDGHLD_00746 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PAMDGHLD_00747 4.5e-262 fliF N The M ring may be actively involved in energy transduction
PAMDGHLD_00748 2.5e-31 fliE N Flagellar hook-basal body
PAMDGHLD_00749 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
PAMDGHLD_00750 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PAMDGHLD_00751 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PAMDGHLD_00752 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PAMDGHLD_00753 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PAMDGHLD_00754 7.2e-172 xerC L tyrosine recombinase XerC
PAMDGHLD_00755 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PAMDGHLD_00756 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PAMDGHLD_00757 1.6e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
PAMDGHLD_00758 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PAMDGHLD_00759 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PAMDGHLD_00760 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
PAMDGHLD_00761 3.5e-305 ylqG
PAMDGHLD_00762 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PAMDGHLD_00763 6.4e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PAMDGHLD_00764 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PAMDGHLD_00765 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PAMDGHLD_00766 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PAMDGHLD_00767 1.3e-61 ylqD S YlqD protein
PAMDGHLD_00768 1.7e-35 ylqC S Belongs to the UPF0109 family
PAMDGHLD_00769 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PAMDGHLD_00770 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PAMDGHLD_00771 9.6e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PAMDGHLD_00772 4.5e-143 S Phosphotransferase enzyme family
PAMDGHLD_00773 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PAMDGHLD_00774 0.0 smc D Required for chromosome condensation and partitioning
PAMDGHLD_00775 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PAMDGHLD_00776 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAMDGHLD_00777 1.8e-128 IQ reductase
PAMDGHLD_00778 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PAMDGHLD_00779 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PAMDGHLD_00780 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PAMDGHLD_00781 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PAMDGHLD_00782 1.3e-154 sdaAA 4.3.1.17 E L-serine dehydratase
PAMDGHLD_00783 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
PAMDGHLD_00784 7.1e-303 yloV S kinase related to dihydroxyacetone kinase
PAMDGHLD_00785 5.5e-59 asp S protein conserved in bacteria
PAMDGHLD_00786 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PAMDGHLD_00787 6.5e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
PAMDGHLD_00788 6.8e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PAMDGHLD_00789 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PAMDGHLD_00790 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PAMDGHLD_00791 6.6e-139 stp 3.1.3.16 T phosphatase
PAMDGHLD_00792 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PAMDGHLD_00793 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PAMDGHLD_00794 7.3e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PAMDGHLD_00795 1.7e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PAMDGHLD_00796 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PAMDGHLD_00797 6.3e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PAMDGHLD_00798 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PAMDGHLD_00799 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PAMDGHLD_00800 1.5e-40 ylzA S Belongs to the UPF0296 family
PAMDGHLD_00801 1e-154 yloC S stress-induced protein
PAMDGHLD_00802 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
PAMDGHLD_00803 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PAMDGHLD_00804 9e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
PAMDGHLD_00805 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
PAMDGHLD_00806 1.8e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
PAMDGHLD_00807 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
PAMDGHLD_00808 3.3e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
PAMDGHLD_00809 4.1e-179 cysP P phosphate transporter
PAMDGHLD_00810 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
PAMDGHLD_00812 1.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PAMDGHLD_00813 4.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PAMDGHLD_00814 6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PAMDGHLD_00815 7.2e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PAMDGHLD_00816 0.0 carB 6.3.5.5 F Belongs to the CarB family
PAMDGHLD_00817 1.2e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PAMDGHLD_00818 1.9e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PAMDGHLD_00819 3.1e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PAMDGHLD_00820 3e-232 pyrP F Xanthine uracil
PAMDGHLD_00821 3.9e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PAMDGHLD_00822 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PAMDGHLD_00823 2e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PAMDGHLD_00824 1.2e-61 dksA T COG1734 DnaK suppressor protein
PAMDGHLD_00825 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PAMDGHLD_00826 8.9e-68 divIVA D Cell division initiation protein
PAMDGHLD_00827 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
PAMDGHLD_00828 5.2e-41 yggT S membrane
PAMDGHLD_00829 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PAMDGHLD_00830 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PAMDGHLD_00831 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
PAMDGHLD_00832 2.2e-38 ylmC S sporulation protein
PAMDGHLD_00833 4e-253 argE 3.5.1.16 E Acetylornithine deacetylase
PAMDGHLD_00834 1.3e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PAMDGHLD_00835 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAMDGHLD_00836 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAMDGHLD_00837 1.2e-161 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PAMDGHLD_00838 0.0 bpr O COG1404 Subtilisin-like serine proteases
PAMDGHLD_00839 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PAMDGHLD_00840 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PAMDGHLD_00841 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PAMDGHLD_00842 1.4e-167 murB 1.3.1.98 M cell wall formation
PAMDGHLD_00843 7.9e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PAMDGHLD_00844 2.2e-185 spoVE D Belongs to the SEDS family
PAMDGHLD_00845 5.9e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PAMDGHLD_00846 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PAMDGHLD_00847 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PAMDGHLD_00848 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
PAMDGHLD_00849 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PAMDGHLD_00850 2.9e-52 ftsL D Essential cell division protein
PAMDGHLD_00851 4.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PAMDGHLD_00852 2e-77 mraZ K Belongs to the MraZ family
PAMDGHLD_00853 5.7e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PAMDGHLD_00854 4.5e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAMDGHLD_00855 3.1e-89 ylbP K n-acetyltransferase
PAMDGHLD_00856 1e-70 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PAMDGHLD_00857 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PAMDGHLD_00858 3.3e-89 yceD S metal-binding, possibly nucleic acid-binding protein
PAMDGHLD_00859 1e-229 ylbM S Belongs to the UPF0348 family
PAMDGHLD_00860 6.1e-188 ylbL T Belongs to the peptidase S16 family
PAMDGHLD_00861 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
PAMDGHLD_00862 2.8e-216 ylbJ S Sporulation integral membrane protein YlbJ
PAMDGHLD_00863 7.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PAMDGHLD_00864 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
PAMDGHLD_00865 7.2e-43 ylbG S UPF0298 protein
PAMDGHLD_00866 4.6e-71 ylbF S Belongs to the UPF0342 family
PAMDGHLD_00867 8.8e-37 ylbE S YlbE-like protein
PAMDGHLD_00868 1.3e-56 ylbD S Putative coat protein
PAMDGHLD_00869 7.8e-199 ylbC S protein with SCP PR1 domains
PAMDGHLD_00870 6.3e-73 ylbB T COG0517 FOG CBS domain
PAMDGHLD_00871 8.5e-60 ylbA S YugN-like family
PAMDGHLD_00872 9.1e-164 ctaG S cytochrome c oxidase
PAMDGHLD_00873 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PAMDGHLD_00874 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PAMDGHLD_00875 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PAMDGHLD_00876 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PAMDGHLD_00877 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PAMDGHLD_00878 2e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PAMDGHLD_00879 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PAMDGHLD_00880 4.5e-214 ftsW D Belongs to the SEDS family
PAMDGHLD_00881 8.7e-44 ylaN S Belongs to the UPF0358 family
PAMDGHLD_00882 5e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
PAMDGHLD_00883 2.9e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PAMDGHLD_00884 8.3e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
PAMDGHLD_00885 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PAMDGHLD_00886 1e-33 ylaI S protein conserved in bacteria
PAMDGHLD_00887 1.3e-48 ylaH S YlaH-like protein
PAMDGHLD_00888 0.0 typA T GTP-binding protein TypA
PAMDGHLD_00889 6.7e-24 S Family of unknown function (DUF5325)
PAMDGHLD_00890 6.3e-39 ylaE
PAMDGHLD_00891 8.3e-13 sigC S Putative zinc-finger
PAMDGHLD_00892 7.9e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
PAMDGHLD_00893 8.9e-83 ykzC S Acetyltransferase (GNAT) family
PAMDGHLD_00894 6.7e-150 suhB 3.1.3.25 G Inositol monophosphatase
PAMDGHLD_00895 9.7e-25 ykzI
PAMDGHLD_00896 4.9e-119 yktB S Belongs to the UPF0637 family
PAMDGHLD_00897 3.5e-42 yktA S Belongs to the UPF0223 family
PAMDGHLD_00898 5.9e-277 speA 4.1.1.19 E Arginine
PAMDGHLD_00899 1.1e-139 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
PAMDGHLD_00900 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
PAMDGHLD_00901 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PAMDGHLD_00902 1.3e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PAMDGHLD_00903 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PAMDGHLD_00904 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PAMDGHLD_00905 5.7e-208 V Beta-lactamase
PAMDGHLD_00906 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
PAMDGHLD_00907 0.0 Q Polyketide synthase of type I
PAMDGHLD_00908 0.0 Q Polyketide synthase of type I
PAMDGHLD_00909 0.0 Q Polyketide synthase of type I
PAMDGHLD_00910 0.0 Q Polyketide synthase of type I
PAMDGHLD_00911 0.0 Q polyketide synthase
PAMDGHLD_00912 0.0 Q Polyketide synthase of type I
PAMDGHLD_00913 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PAMDGHLD_00914 5e-103 recN L Putative cell-wall binding lipoprotein
PAMDGHLD_00916 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PAMDGHLD_00917 1.5e-146 ykrA S hydrolases of the HAD superfamily
PAMDGHLD_00918 8.2e-31 ykzG S Belongs to the UPF0356 family
PAMDGHLD_00919 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PAMDGHLD_00920 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PAMDGHLD_00921 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
PAMDGHLD_00922 4.1e-150 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
PAMDGHLD_00923 6.3e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
PAMDGHLD_00924 2.1e-45 abrB K of stationary sporulation gene expression
PAMDGHLD_00925 7.7e-183 mreB D Rod-share determining protein MreBH
PAMDGHLD_00926 5.5e-12 S Uncharacterized protein YkpC
PAMDGHLD_00927 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PAMDGHLD_00928 2.1e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAMDGHLD_00929 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PAMDGHLD_00930 2.6e-37 ykoA
PAMDGHLD_00931 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PAMDGHLD_00932 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PAMDGHLD_00933 1.2e-166 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
PAMDGHLD_00934 1e-131 fruR K Transcriptional regulator
PAMDGHLD_00935 2.1e-211 yknZ V ABC transporter (permease)
PAMDGHLD_00936 3e-122 macB V ABC transporter, ATP-binding protein
PAMDGHLD_00937 2.6e-171 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAMDGHLD_00938 4.9e-104 yknW S Yip1 domain
PAMDGHLD_00939 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PAMDGHLD_00940 7.1e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
PAMDGHLD_00941 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
PAMDGHLD_00942 1.1e-242 moeA 2.10.1.1 H molybdopterin
PAMDGHLD_00943 1.4e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PAMDGHLD_00944 1.8e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PAMDGHLD_00945 1.1e-160 yknT
PAMDGHLD_00946 4.5e-98 rok K Repressor of ComK
PAMDGHLD_00947 1.6e-79 ykuV CO thiol-disulfide
PAMDGHLD_00948 2.4e-139 ykuT M Mechanosensitive ion channel
PAMDGHLD_00949 4.8e-38 ykuS S Belongs to the UPF0180 family
PAMDGHLD_00950 7.6e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PAMDGHLD_00951 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PAMDGHLD_00952 2.1e-79 fld C Flavodoxin
PAMDGHLD_00953 1.6e-171 ykuO
PAMDGHLD_00954 7.4e-88 fld C Flavodoxin
PAMDGHLD_00955 4.6e-168 ccpC K Transcriptional regulator
PAMDGHLD_00956 1e-75 ykuL S CBS domain
PAMDGHLD_00957 2.1e-25 ykzF S Antirepressor AbbA
PAMDGHLD_00958 4.9e-93 ykuK S Ribonuclease H-like
PAMDGHLD_00959 3.9e-37 ykuJ S protein conserved in bacteria
PAMDGHLD_00960 1.7e-232 ykuI T Diguanylate phosphodiesterase
PAMDGHLD_00962 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAMDGHLD_00963 8.3e-154 ykuE S Metallophosphoesterase
PAMDGHLD_00964 9.2e-89 ykuD S protein conserved in bacteria
PAMDGHLD_00965 3e-240 ykuC EGP Major facilitator Superfamily
PAMDGHLD_00966 1.4e-83 ykyB S YkyB-like protein
PAMDGHLD_00967 2.6e-166 cheV 2.7.13.3 T Chemotaxis protein CheV
PAMDGHLD_00968 2.3e-09
PAMDGHLD_00969 6.7e-215 patA 2.6.1.1 E Aminotransferase
PAMDGHLD_00970 9.8e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
PAMDGHLD_00971 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
PAMDGHLD_00972 1.2e-114 ykwD J protein with SCP PR1 domains
PAMDGHLD_00973 1.9e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PAMDGHLD_00974 5e-263 mcpC NT chemotaxis protein
PAMDGHLD_00975 2.9e-190 splB 4.1.99.14 L Spore photoproduct lyase
PAMDGHLD_00976 6.1e-38 splA S Transcriptional regulator
PAMDGHLD_00977 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PAMDGHLD_00978 2.1e-39 ptsH G phosphocarrier protein HPr
PAMDGHLD_00979 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PAMDGHLD_00980 4.3e-155 glcT K antiterminator
PAMDGHLD_00981 1e-176 ykvZ 5.1.1.1 K Transcriptional regulator
PAMDGHLD_00983 2.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
PAMDGHLD_00984 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PAMDGHLD_00985 5.9e-88 stoA CO thiol-disulfide
PAMDGHLD_00986 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAMDGHLD_00987 1.5e-109 ykvT 3.5.1.28 M Cell Wall Hydrolase
PAMDGHLD_00988 7.9e-28
PAMDGHLD_00989 7.8e-25 ykvS S protein conserved in bacteria
PAMDGHLD_00990 2.2e-44 ykvR S Protein of unknown function (DUF3219)
PAMDGHLD_00991 9.1e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PAMDGHLD_00992 1.1e-130 IQ Enoyl-(Acyl carrier protein) reductase
PAMDGHLD_00993 3.4e-58 ykvN K Transcriptional regulator
PAMDGHLD_00995 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PAMDGHLD_00996 2.2e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PAMDGHLD_00997 1.3e-78 queD 4.1.2.50, 4.2.3.12 H synthase
PAMDGHLD_00998 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PAMDGHLD_00999 2.3e-188
PAMDGHLD_01000 1.5e-181 ykvI S membrane
PAMDGHLD_01001 0.0 clpE O Belongs to the ClpA ClpB family
PAMDGHLD_01002 1.1e-136 motA N flagellar motor
PAMDGHLD_01003 2.7e-127 motB N Flagellar motor protein
PAMDGHLD_01004 5.5e-77 ykvE K transcriptional
PAMDGHLD_01005 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
PAMDGHLD_01006 3.4e-10 S Spo0E like sporulation regulatory protein
PAMDGHLD_01007 2.7e-94 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PAMDGHLD_01008 1e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
PAMDGHLD_01009 1.1e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PAMDGHLD_01010 3.3e-225 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
PAMDGHLD_01011 1.9e-228 mtnE 2.6.1.83 E Aminotransferase
PAMDGHLD_01012 1.9e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PAMDGHLD_01013 1e-226 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PAMDGHLD_01014 4.8e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PAMDGHLD_01016 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PAMDGHLD_01017 0.0 kinE 2.7.13.3 T Histidine kinase
PAMDGHLD_01018 1.2e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
PAMDGHLD_01019 7.9e-24 ykzE
PAMDGHLD_01020 1.7e-114 ydfR S Protein of unknown function (DUF421)
PAMDGHLD_01021 4.3e-242 ktrB P COG0168 Trk-type K transport systems, membrane components
PAMDGHLD_01022 4.1e-156 htpX O Belongs to the peptidase M48B family
PAMDGHLD_01023 1.7e-125 ykrK S Domain of unknown function (DUF1836)
PAMDGHLD_01024 2.5e-26 sspD S small acid-soluble spore protein
PAMDGHLD_01025 3.1e-119 rsgI S Anti-sigma factor N-terminus
PAMDGHLD_01026 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAMDGHLD_01027 4.6e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PAMDGHLD_01028 4.1e-101 ykoX S membrane-associated protein
PAMDGHLD_01029 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PAMDGHLD_01030 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
PAMDGHLD_01031 2.2e-99 ykoP G polysaccharide deacetylase
PAMDGHLD_01032 1.1e-80 ykoM K transcriptional
PAMDGHLD_01033 3.1e-26 ykoL
PAMDGHLD_01034 1.9e-16
PAMDGHLD_01035 5.4e-53 tnrA K transcriptional
PAMDGHLD_01036 5e-238 mgtE P Acts as a magnesium transporter
PAMDGHLD_01038 1.1e-244 ydhD M Glycosyl hydrolase
PAMDGHLD_01039 1.3e-97 ykoE S ABC-type cobalt transport system, permease component
PAMDGHLD_01040 2e-305 P ABC transporter, ATP-binding protein
PAMDGHLD_01041 1.3e-131 ykoC P Cobalt transport protein
PAMDGHLD_01042 6.6e-148 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PAMDGHLD_01043 1.3e-176 isp O Belongs to the peptidase S8 family
PAMDGHLD_01044 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PAMDGHLD_01045 3.3e-112 S AAA ATPase domain
PAMDGHLD_01046 9.3e-124 M PFAM Collagen triple helix repeat (20 copies)
PAMDGHLD_01047 2.2e-215 M Glycosyl transferase family 2
PAMDGHLD_01049 2.3e-59 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PAMDGHLD_01050 4.6e-70 ohrB O Organic hydroperoxide resistance protein
PAMDGHLD_01051 4.8e-85 ohrR K COG1846 Transcriptional regulators
PAMDGHLD_01052 5.7e-71 ohrA O Organic hydroperoxide resistance protein
PAMDGHLD_01053 1.8e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PAMDGHLD_01054 6e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PAMDGHLD_01055 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
PAMDGHLD_01056 5e-48 ykkD P Multidrug resistance protein
PAMDGHLD_01057 8e-52 ykkC P Multidrug resistance protein
PAMDGHLD_01058 1.1e-100 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PAMDGHLD_01059 1.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
PAMDGHLD_01060 1.1e-158 ykgA E Amidinotransferase
PAMDGHLD_01061 1.1e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
PAMDGHLD_01062 2.1e-182 ykfD E Belongs to the ABC transporter superfamily
PAMDGHLD_01063 1.1e-169 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PAMDGHLD_01064 9.7e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
PAMDGHLD_01065 2.1e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
PAMDGHLD_01066 0.0 dppE E ABC transporter substrate-binding protein
PAMDGHLD_01067 5.5e-189 dppD P Belongs to the ABC transporter superfamily
PAMDGHLD_01068 8.5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAMDGHLD_01069 2.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAMDGHLD_01070 6.5e-156 dppA E D-aminopeptidase
PAMDGHLD_01071 3.3e-286 yubD P Major Facilitator Superfamily
PAMDGHLD_01072 4.3e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAMDGHLD_01074 2.9e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PAMDGHLD_01075 6e-310 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PAMDGHLD_01076 4.8e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
PAMDGHLD_01077 1.2e-242 steT E amino acid
PAMDGHLD_01078 3.2e-107 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
PAMDGHLD_01079 2e-175 pit P phosphate transporter
PAMDGHLD_01080 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
PAMDGHLD_01081 8.7e-23 spoIISB S Stage II sporulation protein SB
PAMDGHLD_01082 6e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PAMDGHLD_01083 1.3e-38 xhlB S SPP1 phage holin
PAMDGHLD_01084 8.7e-38 xhlA S Haemolysin XhlA
PAMDGHLD_01085 4.3e-138 xepA
PAMDGHLD_01086 2.5e-29 xkdX
PAMDGHLD_01088 8.4e-91
PAMDGHLD_01089 9.3e-27
PAMDGHLD_01090 1.4e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
PAMDGHLD_01091 2.5e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PAMDGHLD_01092 6.1e-57 xkdS S Protein of unknown function (DUF2634)
PAMDGHLD_01093 7.2e-32 xkdR S Protein of unknown function (DUF2577)
PAMDGHLD_01094 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
PAMDGHLD_01095 6.6e-111 xkdP S Lysin motif
PAMDGHLD_01096 1.3e-177 xkdO L Transglycosylase SLT domain
PAMDGHLD_01097 3.4e-19
PAMDGHLD_01098 4.9e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
PAMDGHLD_01099 2e-74 xkdM S Phage tail tube protein
PAMDGHLD_01100 1e-225 xkdK S Phage tail sheath C-terminal domain
PAMDGHLD_01101 3.1e-14
PAMDGHLD_01102 2.2e-57 xkdJ
PAMDGHLD_01103 5.9e-59 xkdI S Bacteriophage HK97-gp10, putative tail-component
PAMDGHLD_01104 4.2e-43 yqbH S Domain of unknown function (DUF3599)
PAMDGHLD_01105 2.2e-45 yqbG S Protein of unknown function (DUF3199)
PAMDGHLD_01106 1e-157 xkdG S Phage capsid family
PAMDGHLD_01107 5.7e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
PAMDGHLD_01108 7.9e-242 yqbA S portal protein
PAMDGHLD_01109 4.7e-209 xtmB S phage terminase, large subunit
PAMDGHLD_01110 1.6e-111 xtmA L phage terminase small subunit
PAMDGHLD_01111 6.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PAMDGHLD_01112 2e-10 yqaO S Phage-like element PBSX protein XtrA
PAMDGHLD_01115 7.2e-152 xkdC L Bacterial dnaA protein
PAMDGHLD_01117 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
PAMDGHLD_01118 7.8e-111 xkdA E IrrE N-terminal-like domain
PAMDGHLD_01119 6.1e-111 yjqB S phage-related replication protein
PAMDGHLD_01120 4.7e-61 yjqA S Bacterial PH domain
PAMDGHLD_01121 1.9e-167 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PAMDGHLD_01123 4.9e-215 S response regulator aspartate phosphatase
PAMDGHLD_01124 3.1e-78 yjoA S DinB family
PAMDGHLD_01125 3.9e-131 MA20_18170 S membrane transporter protein
PAMDGHLD_01126 4.1e-205 salB V Domain of unknown function (DUF4135)
PAMDGHLD_01129 2.1e-214 lanT 3.6.3.27 V Peptidase C39 family
PAMDGHLD_01130 6.7e-302 lcnDR2 V Lanthionine synthetase C-like protein
PAMDGHLD_01132 7e-60 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAMDGHLD_01133 1.8e-45 narQ 2.7.13.3 T Histidine kinase
PAMDGHLD_01135 3.8e-67 S ABC-2 family transporter protein
PAMDGHLD_01136 7e-106 V ABC transporter, ATP-binding protein
PAMDGHLD_01137 4.5e-130 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PAMDGHLD_01138 1.8e-87 T Transcriptional regulatory protein, C terminal
PAMDGHLD_01139 2.7e-277 uxaA 4.2.1.7, 4.4.1.24 G Altronate
PAMDGHLD_01140 7.3e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
PAMDGHLD_01141 3.4e-183 exuR K transcriptional
PAMDGHLD_01142 6.7e-254 yjmB G symporter YjmB
PAMDGHLD_01143 8.7e-278 uxaC 5.3.1.12 G glucuronate isomerase
PAMDGHLD_01144 3.8e-218 yjlD 1.6.99.3 C NADH dehydrogenase
PAMDGHLD_01145 7e-66 yjlC S Protein of unknown function (DUF1641)
PAMDGHLD_01146 5.7e-91 yjlB S Cupin domain
PAMDGHLD_01147 1e-176 yjlA EG Putative multidrug resistance efflux transporter
PAMDGHLD_01148 1.9e-130 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
PAMDGHLD_01149 3.7e-124 ybbM S transport system, permease component
PAMDGHLD_01150 4.6e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PAMDGHLD_01151 6.8e-29
PAMDGHLD_01152 1.7e-221 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PAMDGHLD_01153 1.2e-227 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
PAMDGHLD_01154 4.3e-92 yjgD S Protein of unknown function (DUF1641)
PAMDGHLD_01155 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
PAMDGHLD_01156 5.9e-100 yjgB S Domain of unknown function (DUF4309)
PAMDGHLD_01157 1.1e-68 T PhoQ Sensor
PAMDGHLD_01158 7.5e-22 yjfB S Putative motility protein
PAMDGHLD_01160 6.8e-105 yhiD S MgtC SapB transporter
PAMDGHLD_01161 7.7e-52 K helix_turn_helix multiple antibiotic resistance protein
PAMDGHLD_01162 9.1e-35
PAMDGHLD_01163 3.5e-123 5.4.2.6 S Haloacid dehalogenase-like hydrolase
PAMDGHLD_01164 1.4e-136 lacR K COG1349 Transcriptional regulators of sugar metabolism
PAMDGHLD_01165 3.1e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
PAMDGHLD_01166 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
PAMDGHLD_01167 8e-310 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAMDGHLD_01168 1.1e-214 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PAMDGHLD_01169 6.3e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PAMDGHLD_01170 1.3e-290 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PAMDGHLD_01171 7.8e-221 ganA 3.2.1.89 G arabinogalactan
PAMDGHLD_01172 1.4e-81 napB K helix_turn_helix multiple antibiotic resistance protein
PAMDGHLD_01173 2.4e-251 yfjF EGP Belongs to the major facilitator superfamily
PAMDGHLD_01174 1.4e-46 yjcS S Antibiotic biosynthesis monooxygenase
PAMDGHLD_01175 6.1e-147 bla 3.5.2.6 V beta-lactamase
PAMDGHLD_01176 3.5e-59 E Glyoxalase-like domain
PAMDGHLD_01180 1.9e-200 M nucleic acid phosphodiester bond hydrolysis
PAMDGHLD_01181 2.2e-29
PAMDGHLD_01182 3.5e-38
PAMDGHLD_01183 6.9e-23
PAMDGHLD_01184 1.3e-19
PAMDGHLD_01186 2.4e-212 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PAMDGHLD_01187 3.5e-213 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PAMDGHLD_01188 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
PAMDGHLD_01189 2.4e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
PAMDGHLD_01190 2.1e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAMDGHLD_01191 9.4e-36 K SpoVT / AbrB like domain
PAMDGHLD_01192 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
PAMDGHLD_01193 5.2e-125 S ABC-2 type transporter
PAMDGHLD_01194 3.7e-142 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
PAMDGHLD_01195 7.9e-36
PAMDGHLD_01196 0.0 yjcD 3.6.4.12 L DNA helicase
PAMDGHLD_01197 3.8e-38 spoVIF S Stage VI sporulation protein F
PAMDGHLD_01201 1.6e-55 yjcA S Protein of unknown function (DUF1360)
PAMDGHLD_01202 1.4e-39 cotV S Spore Coat Protein X and V domain
PAMDGHLD_01203 2.1e-22 cotW
PAMDGHLD_01204 5.1e-71 cotX S Spore Coat Protein X and V domain
PAMDGHLD_01205 1.7e-92 cotY S Spore coat protein Z
PAMDGHLD_01206 6.7e-83 cotZ S Spore coat protein
PAMDGHLD_01207 9.5e-88 yjbX S Spore coat protein
PAMDGHLD_01208 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PAMDGHLD_01209 8.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PAMDGHLD_01210 1.8e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PAMDGHLD_01211 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PAMDGHLD_01212 1.4e-30 thiS H Thiamine biosynthesis
PAMDGHLD_01213 6.6e-212 thiO 1.4.3.19 E Glycine oxidase
PAMDGHLD_01214 1.9e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
PAMDGHLD_01215 4.9e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PAMDGHLD_01216 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PAMDGHLD_01217 4e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PAMDGHLD_01218 9.1e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PAMDGHLD_01219 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PAMDGHLD_01220 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
PAMDGHLD_01221 8.6e-60 yjbL S Belongs to the UPF0738 family
PAMDGHLD_01222 1.3e-99 yjbK S protein conserved in bacteria
PAMDGHLD_01223 9.9e-118 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PAMDGHLD_01224 4.1e-71 yjbI S Bacterial-like globin
PAMDGHLD_01225 5.1e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PAMDGHLD_01226 1.9e-17
PAMDGHLD_01227 0.0 pepF E oligoendopeptidase F
PAMDGHLD_01228 3.1e-220 yjbF S Competence protein
PAMDGHLD_01229 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PAMDGHLD_01230 1.8e-108 yjbE P Integral membrane protein TerC family
PAMDGHLD_01231 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PAMDGHLD_01232 5.8e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAMDGHLD_01233 1.2e-230 S Putative glycosyl hydrolase domain
PAMDGHLD_01234 1.1e-169 oppF E Belongs to the ABC transporter superfamily
PAMDGHLD_01235 2.7e-202 oppD P Belongs to the ABC transporter superfamily
PAMDGHLD_01236 5.3e-159 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAMDGHLD_01237 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAMDGHLD_01238 0.0 oppA E ABC transporter substrate-binding protein
PAMDGHLD_01239 7.5e-183 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PAMDGHLD_01240 5.5e-146 yjbA S Belongs to the UPF0736 family
PAMDGHLD_01241 3.6e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAMDGHLD_01242 7e-170 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAMDGHLD_01243 1.8e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
PAMDGHLD_01244 2.2e-187 appF E Belongs to the ABC transporter superfamily
PAMDGHLD_01245 2.2e-182 appD P Belongs to the ABC transporter superfamily
PAMDGHLD_01246 1.6e-148 yjaZ O Zn-dependent protease
PAMDGHLD_01247 1.7e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PAMDGHLD_01248 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAMDGHLD_01249 1.5e-30 yjzB
PAMDGHLD_01250 1.1e-26 comZ S ComZ
PAMDGHLD_01251 1.9e-166 med S Transcriptional activator protein med
PAMDGHLD_01252 2.3e-104 yjaV
PAMDGHLD_01253 4.6e-137 yjaU I carboxylic ester hydrolase activity
PAMDGHLD_01254 2.8e-22 yjzD S Protein of unknown function (DUF2929)
PAMDGHLD_01255 1.2e-27 yjzC S YjzC-like protein
PAMDGHLD_01256 2.3e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PAMDGHLD_01257 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
PAMDGHLD_01258 1.5e-202 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PAMDGHLD_01259 5.8e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PAMDGHLD_01260 8.3e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
PAMDGHLD_01261 6.7e-226 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PAMDGHLD_01262 2.8e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PAMDGHLD_01263 1.2e-89 norB G Major Facilitator Superfamily
PAMDGHLD_01264 1.5e-272 yitY C D-arabinono-1,4-lactone oxidase
PAMDGHLD_01265 1e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
PAMDGHLD_01266 1.8e-50 yitW S metal-sulfur cluster biosynthetic enzyme
PAMDGHLD_01267 4.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
PAMDGHLD_01268 5.1e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PAMDGHLD_01269 3.5e-07
PAMDGHLD_01270 4.4e-26 S Protein of unknown function (DUF3813)
PAMDGHLD_01271 2.9e-81 ipi S Intracellular proteinase inhibitor
PAMDGHLD_01272 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
PAMDGHLD_01273 4.9e-159 yitS S protein conserved in bacteria
PAMDGHLD_01275 2.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
PAMDGHLD_01276 2e-209 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
PAMDGHLD_01277 1.3e-171 yufN S ABC transporter substrate-binding protein PnrA-like
PAMDGHLD_01278 2.6e-160 cvfB S protein conserved in bacteria
PAMDGHLD_01279 6.6e-55 yajQ S Belongs to the UPF0234 family
PAMDGHLD_01280 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PAMDGHLD_01281 1.2e-79 yjcF S Acetyltransferase (GNAT) domain
PAMDGHLD_01282 1.7e-71 mcbG S Pentapeptide repeats (9 copies)
PAMDGHLD_01283 3.7e-191 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PAMDGHLD_01284 7.8e-74 argO S Lysine exporter protein LysE YggA
PAMDGHLD_01285 2e-88 yisT S DinB family
PAMDGHLD_01286 5.1e-25 yisS 1.1.1.370 S Oxidoreductase family, NAD-binding Rossmann fold
PAMDGHLD_01287 1.7e-159 yisR K Transcriptional regulator
PAMDGHLD_01288 2.5e-245 yisQ V Mate efflux family protein
PAMDGHLD_01289 1e-131 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
PAMDGHLD_01290 0.0 asnO 6.3.5.4 E Asparagine synthase
PAMDGHLD_01291 1.3e-96 yisN S Protein of unknown function (DUF2777)
PAMDGHLD_01292 1.1e-59 yisL S UPF0344 protein
PAMDGHLD_01293 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PAMDGHLD_01294 5e-07 yisI S Spo0E like sporulation regulatory protein
PAMDGHLD_01295 8.4e-34 gerPA S Spore germination protein
PAMDGHLD_01296 6.2e-35 gerPB S cell differentiation
PAMDGHLD_01297 1.4e-62 gerPC S Spore germination protein
PAMDGHLD_01298 3.1e-23 gerPD S Spore germination protein
PAMDGHLD_01299 1.2e-62 gerPE S Spore germination protein GerPE
PAMDGHLD_01300 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
PAMDGHLD_01301 1.4e-49 yisB V COG1403 Restriction endonuclease
PAMDGHLD_01302 0.0 sbcC L COG0419 ATPase involved in DNA repair
PAMDGHLD_01303 1.3e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PAMDGHLD_01304 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PAMDGHLD_01305 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
PAMDGHLD_01306 1.4e-119 ydfS S Protein of unknown function (DUF421)
PAMDGHLD_01307 2.2e-93 yhjR S Rubrerythrin
PAMDGHLD_01308 1.9e-107 K QacR-like protein, C-terminal region
PAMDGHLD_01309 3e-202 blt EGP Major facilitator Superfamily
PAMDGHLD_01310 1.8e-188 abrB S membrane
PAMDGHLD_01311 8.4e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
PAMDGHLD_01312 2.3e-268 yhjG CH FAD binding domain
PAMDGHLD_01313 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
PAMDGHLD_01314 7.7e-109 yhjE S SNARE associated Golgi protein
PAMDGHLD_01315 1.7e-60 yhjD
PAMDGHLD_01316 3.1e-27 yhjC S Protein of unknown function (DUF3311)
PAMDGHLD_01317 3.8e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAMDGHLD_01318 3.3e-47 S Belongs to the UPF0145 family
PAMDGHLD_01319 1.6e-42 yhjA S Excalibur calcium-binding domain
PAMDGHLD_01320 8.7e-125 yrpD S Domain of unknown function, YrpD
PAMDGHLD_01321 6.5e-63 frataxin S Domain of unknown function (DU1801)
PAMDGHLD_01322 4.3e-67 frataxin S Domain of unknown function (DU1801)
PAMDGHLD_01323 1.9e-109 comK K Competence transcription factor
PAMDGHLD_01324 5.4e-31 yhzC S IDEAL
PAMDGHLD_01325 8.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAMDGHLD_01326 6.5e-295 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
PAMDGHLD_01327 5.7e-199 hemAT NT chemotaxis protein
PAMDGHLD_01328 3.5e-89 bioY S BioY family
PAMDGHLD_01329 7.3e-280 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
PAMDGHLD_01330 2.8e-199 vraB 2.3.1.9 I Belongs to the thiolase family
PAMDGHLD_01331 2.6e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
PAMDGHLD_01332 8.7e-151 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PAMDGHLD_01333 4.4e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
PAMDGHLD_01334 1.4e-234 yhfN 3.4.24.84 O Peptidase M48
PAMDGHLD_01335 1.3e-64 yhfM
PAMDGHLD_01336 1.9e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
PAMDGHLD_01337 1.1e-110 yhfK GM NmrA-like family
PAMDGHLD_01338 3.5e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
PAMDGHLD_01339 1.3e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
PAMDGHLD_01340 7.9e-11 yhfH S YhfH-like protein
PAMDGHLD_01341 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PAMDGHLD_01342 9.5e-197 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
PAMDGHLD_01344 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAMDGHLD_01345 7.2e-245 yhgE S YhgE Pip N-terminal domain protein
PAMDGHLD_01346 4.1e-101 yhgD K Transcriptional regulator
PAMDGHLD_01347 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PAMDGHLD_01348 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PAMDGHLD_01349 2.8e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PAMDGHLD_01350 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PAMDGHLD_01351 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PAMDGHLD_01352 1.8e-243 yhfA C membrane
PAMDGHLD_01353 7.2e-225 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PAMDGHLD_01354 2.8e-123 ecsC S EcsC protein family
PAMDGHLD_01355 1.9e-220 ecsB U ABC transporter
PAMDGHLD_01356 7.4e-135 ecsA V transporter (ATP-binding protein)
PAMDGHLD_01357 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PAMDGHLD_01358 2.1e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PAMDGHLD_01359 2.9e-77 trpP S Tryptophan transporter TrpP
PAMDGHLD_01360 2e-17
PAMDGHLD_01361 6.2e-39 yhaH S YtxH-like protein
PAMDGHLD_01362 3.3e-112 hpr K Negative regulator of protease production and sporulation
PAMDGHLD_01363 9.9e-55 yhaI S Protein of unknown function (DUF1878)
PAMDGHLD_01364 7e-95 yhaK S Putative zincin peptidase
PAMDGHLD_01365 2.6e-115 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PAMDGHLD_01366 3.6e-32 yhaL S Sporulation protein YhaL
PAMDGHLD_01367 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
PAMDGHLD_01368 0.0 yhaN L AAA domain
PAMDGHLD_01369 4.2e-236 yhaO L DNA repair exonuclease
PAMDGHLD_01370 8e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
PAMDGHLD_01371 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
PAMDGHLD_01372 7.3e-15 S YhzD-like protein
PAMDGHLD_01373 4.5e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
PAMDGHLD_01375 9.5e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
PAMDGHLD_01376 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
PAMDGHLD_01377 3.7e-251 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
PAMDGHLD_01378 9.3e-294 hemZ H coproporphyrinogen III oxidase
PAMDGHLD_01379 3.3e-158 yhaX S haloacid dehalogenase-like hydrolase
PAMDGHLD_01380 3.2e-198 yhaZ L DNA alkylation repair enzyme
PAMDGHLD_01381 4.4e-53 yheA S Belongs to the UPF0342 family
PAMDGHLD_01382 7.2e-206 yheB S Belongs to the UPF0754 family
PAMDGHLD_01383 3.1e-214 yheC HJ YheC/D like ATP-grasp
PAMDGHLD_01384 3.7e-260 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
PAMDGHLD_01385 1.7e-36 yheE S Family of unknown function (DUF5342)
PAMDGHLD_01386 1.3e-28 sspB S spore protein
PAMDGHLD_01388 2.4e-110 yheG GM NAD(P)H-binding
PAMDGHLD_01389 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
PAMDGHLD_01390 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
PAMDGHLD_01392 2.1e-85 T universal stress protein
PAMDGHLD_01393 1.8e-93 ymcC S Membrane
PAMDGHLD_01394 3e-87 pksA K Transcriptional regulator
PAMDGHLD_01395 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PAMDGHLD_01396 1.3e-156 yheN G deacetylase
PAMDGHLD_01397 4.5e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PAMDGHLD_01398 1e-204 yhdY M Mechanosensitive ion channel
PAMDGHLD_01400 6.5e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PAMDGHLD_01401 9.3e-60 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAMDGHLD_01402 7.9e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAMDGHLD_01403 2.9e-257 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
PAMDGHLD_01404 2.8e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PAMDGHLD_01405 4.2e-225 yhdR 2.6.1.1 E Aminotransferase
PAMDGHLD_01406 4.3e-71 cueR K transcriptional
PAMDGHLD_01407 1.6e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PAMDGHLD_01408 1.9e-109 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PAMDGHLD_01409 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
PAMDGHLD_01410 6.6e-201 yhdL S Sigma factor regulator N-terminal
PAMDGHLD_01411 8.1e-45 yhdK S Sigma-M inhibitor protein
PAMDGHLD_01412 1.4e-197 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PAMDGHLD_01413 1.5e-250 yhdG E amino acid
PAMDGHLD_01414 4.6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAMDGHLD_01415 3.9e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
PAMDGHLD_01416 5.8e-163 citR K Transcriptional regulator
PAMDGHLD_01417 2.2e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PAMDGHLD_01418 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
PAMDGHLD_01419 1.2e-271 ycgB S Stage V sporulation protein R
PAMDGHLD_01420 2.9e-255 ygxB M Conserved TM helix
PAMDGHLD_01421 1.6e-73 nsrR K Transcriptional regulator
PAMDGHLD_01422 1.5e-216 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PAMDGHLD_01423 3.1e-53 yhdC S Protein of unknown function (DUF3889)
PAMDGHLD_01424 3.6e-38 yhdB S YhdB-like protein
PAMDGHLD_01425 3.3e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
PAMDGHLD_01426 1.4e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAMDGHLD_01427 5.5e-206 yhcY 2.7.13.3 T Histidine kinase
PAMDGHLD_01428 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PAMDGHLD_01429 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PAMDGHLD_01430 1.2e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PAMDGHLD_01431 1.2e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
PAMDGHLD_01432 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PAMDGHLD_01433 9.3e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAMDGHLD_01434 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PAMDGHLD_01435 4.9e-125 yhcW 5.4.2.6 S hydrolase
PAMDGHLD_01436 2.6e-68 yhcV S COG0517 FOG CBS domain
PAMDGHLD_01437 1.6e-67 yhcU S Family of unknown function (DUF5365)
PAMDGHLD_01438 5.6e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PAMDGHLD_01439 4.4e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
PAMDGHLD_01440 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
PAMDGHLD_01441 7.6e-115 yhcQ M Spore coat protein
PAMDGHLD_01442 8.9e-159 yhcP
PAMDGHLD_01443 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PAMDGHLD_01444 5.6e-49 yhcM
PAMDGHLD_01445 3.5e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PAMDGHLD_01446 6.7e-185 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
PAMDGHLD_01447 1.1e-147 metQ M Belongs to the nlpA lipoprotein family
PAMDGHLD_01448 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
PAMDGHLD_01449 3.7e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PAMDGHLD_01450 6.4e-70 yhcH V ABC transporter, ATP-binding protein
PAMDGHLD_01451 3.8e-55 yhcC
PAMDGHLD_01452 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
PAMDGHLD_01453 8.4e-285 yhcA EGP Major facilitator Superfamily
PAMDGHLD_01454 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
PAMDGHLD_01455 4.6e-74 yhbI K DNA-binding transcription factor activity
PAMDGHLD_01456 3e-215 yhbH S Belongs to the UPF0229 family
PAMDGHLD_01457 0.0 prkA T Ser protein kinase
PAMDGHLD_01459 1.3e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
PAMDGHLD_01460 5.2e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
PAMDGHLD_01461 8.6e-108 yhbD K Protein of unknown function (DUF4004)
PAMDGHLD_01462 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PAMDGHLD_01463 1.4e-175 yhbB S Putative amidase domain
PAMDGHLD_01464 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PAMDGHLD_01465 3e-113 yhzB S B3/4 domain
PAMDGHLD_01467 4.8e-23 K Transcriptional regulator
PAMDGHLD_01468 6.6e-81 ygaO
PAMDGHLD_01469 1.6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PAMDGHLD_01470 1e-212 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
PAMDGHLD_01471 2e-144 ssuC P ABC transporter (permease)
PAMDGHLD_01472 1.7e-174 ssuA M Sulfonate ABC transporter
PAMDGHLD_01473 1e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PAMDGHLD_01474 9.8e-185 S Amidohydrolase
PAMDGHLD_01475 3e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PAMDGHLD_01476 1.1e-133 oppF3 E Belongs to the ABC transporter superfamily
PAMDGHLD_01477 3.7e-134 oppD3 P Belongs to the ABC transporter superfamily
PAMDGHLD_01478 3.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAMDGHLD_01479 9.2e-138 appB P Binding-protein-dependent transport system inner membrane component
PAMDGHLD_01480 5e-227 oppA5 E PFAM extracellular solute-binding protein family 5
PAMDGHLD_01482 4.5e-263 ygaK C Berberine and berberine like
PAMDGHLD_01483 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PAMDGHLD_01484 1.7e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
PAMDGHLD_01485 3.4e-206 C Na+/H+ antiporter family
PAMDGHLD_01489 1.6e-08
PAMDGHLD_01497 7.8e-08
PAMDGHLD_01502 3.4e-39 S COG NOG14552 non supervised orthologous group
PAMDGHLD_01503 8.2e-165 ygxA S Nucleotidyltransferase-like
PAMDGHLD_01504 1.5e-56 ygzB S UPF0295 protein
PAMDGHLD_01505 1.8e-80 perR P Belongs to the Fur family
PAMDGHLD_01506 4.5e-85 bcp 1.11.1.15 O Peroxiredoxin
PAMDGHLD_01507 2.3e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
PAMDGHLD_01508 1.6e-178 ygaE S Membrane
PAMDGHLD_01509 7.7e-300 ygaD V ABC transporter
PAMDGHLD_01510 2.2e-104 ygaC J Belongs to the UPF0374 family
PAMDGHLD_01511 1.5e-37 ygaB S YgaB-like protein
PAMDGHLD_01513 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAMDGHLD_01514 8.2e-37 yfhS
PAMDGHLD_01515 4.7e-210 mutY L A G-specific
PAMDGHLD_01516 1e-184 yfhP S membrane-bound metal-dependent
PAMDGHLD_01517 0.0 yfhO S Bacterial membrane protein YfhO
PAMDGHLD_01518 3e-184 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PAMDGHLD_01519 9.7e-171 yfhM S Alpha/beta hydrolase family
PAMDGHLD_01520 5.7e-34 yfhL S SdpI/YhfL protein family
PAMDGHLD_01521 1.9e-92 batE T Bacterial SH3 domain homologues
PAMDGHLD_01522 2.2e-44 yfhJ S WVELL protein
PAMDGHLD_01523 4.5e-166 mpr 3.4.21.19 M Belongs to the peptidase S1B family
PAMDGHLD_01525 1.5e-206 yfhI EGP Major facilitator Superfamily
PAMDGHLD_01526 8.8e-53 yfhH S Protein of unknown function (DUF1811)
PAMDGHLD_01527 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
PAMDGHLD_01528 1.1e-164 yfhF S nucleoside-diphosphate sugar epimerase
PAMDGHLD_01530 2.1e-25 yfhD S YfhD-like protein
PAMDGHLD_01531 6.3e-105 yfhC C nitroreductase
PAMDGHLD_01532 2.4e-164 yfhB 5.3.3.17 S PhzF family
PAMDGHLD_01533 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PAMDGHLD_01534 2.8e-82 yfiV K transcriptional
PAMDGHLD_01535 1.3e-290 yfiU EGP Major facilitator Superfamily
PAMDGHLD_01536 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
PAMDGHLD_01537 9.9e-45 yrdF K ribonuclease inhibitor
PAMDGHLD_01538 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
PAMDGHLD_01539 1e-180 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PAMDGHLD_01540 1.1e-112 1.6.5.2 S NADPH-dependent FMN reductase
PAMDGHLD_01541 1.7e-96 padR K transcriptional
PAMDGHLD_01542 1.3e-168 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PAMDGHLD_01543 7.7e-160 yfiE 1.13.11.2 S glyoxalase
PAMDGHLD_01544 7e-63 mhqP S DoxX
PAMDGHLD_01545 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
PAMDGHLD_01546 0.0 yfiB3 V ABC transporter
PAMDGHLD_01547 5.6e-225 yobO M COG5434 Endopolygalacturonase
PAMDGHLD_01548 5.9e-184 yobO M COG5434 Endopolygalacturonase
PAMDGHLD_01549 3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PAMDGHLD_01550 8.7e-139 glvR F Helix-turn-helix domain, rpiR family
PAMDGHLD_01551 1.7e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PAMDGHLD_01552 4.2e-15 sspH S Belongs to the SspH family
PAMDGHLD_01553 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
PAMDGHLD_01554 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PAMDGHLD_01555 6.4e-213 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PAMDGHLD_01556 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PAMDGHLD_01557 6.4e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PAMDGHLD_01558 1.4e-89 yfjM S Psort location Cytoplasmic, score
PAMDGHLD_01559 1.8e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PAMDGHLD_01560 1.5e-46 S YfzA-like protein
PAMDGHLD_01561 5.6e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PAMDGHLD_01562 4.7e-157 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PAMDGHLD_01563 8.5e-184 corA P Mediates influx of magnesium ions
PAMDGHLD_01564 8.7e-31
PAMDGHLD_01565 1.4e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PAMDGHLD_01566 8.9e-110 T PhoQ Sensor
PAMDGHLD_01567 4.1e-106 K Two component transcriptional regulator, winged helix family
PAMDGHLD_01568 9.4e-72 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
PAMDGHLD_01569 3.7e-80 S Bacitracin ABC transporter permease
PAMDGHLD_01570 1.3e-144 bcrA V ABC transporter
PAMDGHLD_01571 4.5e-154 pdaA G deacetylase
PAMDGHLD_01572 4.9e-27 yfjT
PAMDGHLD_01573 6e-221 yfkA S YfkB-like domain
PAMDGHLD_01574 3.3e-147 yfkC M Mechanosensitive ion channel
PAMDGHLD_01575 4.2e-144 yfkD S YfkD-like protein
PAMDGHLD_01576 6.5e-185 cax P COG0387 Ca2 H antiporter
PAMDGHLD_01577 9.9e-208 ycaD EGP COG0477 Permeases of the major facilitator superfamily
PAMDGHLD_01578 2.5e-07
PAMDGHLD_01579 1.2e-144 yihY S Belongs to the UPF0761 family
PAMDGHLD_01580 3.5e-52 yfkI S gas vesicle protein
PAMDGHLD_01581 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAMDGHLD_01582 2.7e-29 yfkK S Belongs to the UPF0435 family
PAMDGHLD_01583 1.5e-193 ydiM EGP Major facilitator Superfamily
PAMDGHLD_01584 1.3e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PAMDGHLD_01585 4.5e-163 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PAMDGHLD_01586 8.9e-187 K helix_turn _helix lactose operon repressor
PAMDGHLD_01587 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
PAMDGHLD_01588 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
PAMDGHLD_01589 2.1e-194 yibE S YibE/F-like protein
PAMDGHLD_01590 4.2e-125 yibF S YibE/F-like protein
PAMDGHLD_01591 2e-123 yfkO C nitroreductase
PAMDGHLD_01592 4.5e-129 treR K transcriptional
PAMDGHLD_01593 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PAMDGHLD_01594 9.5e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PAMDGHLD_01595 5.6e-37 ydgB S Spore germination protein gerPA/gerPF
PAMDGHLD_01596 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
PAMDGHLD_01597 3.7e-78 cotP O Belongs to the small heat shock protein (HSP20) family
PAMDGHLD_01598 7.8e-64 yhdN S Domain of unknown function (DUF1992)
PAMDGHLD_01599 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PAMDGHLD_01600 4.8e-73 yfmQ S Uncharacterised protein from bacillus cereus group
PAMDGHLD_01601 1.9e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
PAMDGHLD_01602 1.4e-136 map 3.4.11.18 E Methionine aminopeptidase
PAMDGHLD_01603 3.1e-50 yflH S Protein of unknown function (DUF3243)
PAMDGHLD_01604 9.1e-19 yflI
PAMDGHLD_01605 1.5e-14 yflJ S Protein of unknown function (DUF2639)
PAMDGHLD_01606 3.2e-121 yflK S protein conserved in bacteria
PAMDGHLD_01607 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PAMDGHLD_01608 9.3e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PAMDGHLD_01609 3.3e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
PAMDGHLD_01610 5.5e-226 citM C Citrate transporter
PAMDGHLD_01611 1.8e-178 yflP S Tripartite tricarboxylate transporter family receptor
PAMDGHLD_01612 1.8e-119 citT T response regulator
PAMDGHLD_01613 3e-274 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PAMDGHLD_01614 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
PAMDGHLD_01615 3.3e-23 M1-820 Q Collagen triple helix repeat (20 copies)
PAMDGHLD_01618 2.7e-14 Q calcium- and calmodulin-responsive adenylate cyclase activity
PAMDGHLD_01620 2.1e-28 Q PFAM Collagen triple helix
PAMDGHLD_01621 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
PAMDGHLD_01622 9.1e-242 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
PAMDGHLD_01623 1.3e-57 yflT S Heat induced stress protein YflT
PAMDGHLD_01624 1.2e-24 S Protein of unknown function (DUF3212)
PAMDGHLD_01625 2.6e-186 yfmJ S N-terminal domain of oxidoreductase
PAMDGHLD_01626 4.6e-63 yfmK 2.3.1.128 K acetyltransferase
PAMDGHLD_01627 2.1e-205 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
PAMDGHLD_01628 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PAMDGHLD_01629 3e-207 yfmO EGP Major facilitator Superfamily
PAMDGHLD_01630 9e-69 yfmP K transcriptional
PAMDGHLD_01631 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PAMDGHLD_01632 3.2e-208 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PAMDGHLD_01633 2e-166 IQ Enoyl-(Acyl carrier protein) reductase
PAMDGHLD_01634 9.8e-115 yfmS NT chemotaxis protein
PAMDGHLD_01635 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PAMDGHLD_01636 3e-246 yfnA E amino acid
PAMDGHLD_01637 1e-218 fsr P COG0477 Permeases of the major facilitator superfamily
PAMDGHLD_01638 8.1e-187 yfnD M Nucleotide-diphospho-sugar transferase
PAMDGHLD_01639 1.1e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
PAMDGHLD_01640 1e-178 yfnF M Nucleotide-diphospho-sugar transferase
PAMDGHLD_01641 9.2e-172 yfnG 4.2.1.45 M dehydratase
PAMDGHLD_01642 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
PAMDGHLD_01643 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PAMDGHLD_01645 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
PAMDGHLD_01646 6.4e-196 yetN S Protein of unknown function (DUF3900)
PAMDGHLD_01647 2.8e-210 yetM CH FAD binding domain
PAMDGHLD_01648 5e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
PAMDGHLD_01649 4.1e-105 yetJ S Belongs to the BI1 family
PAMDGHLD_01650 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
PAMDGHLD_01651 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
PAMDGHLD_01652 1.7e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PAMDGHLD_01653 3.4e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAMDGHLD_01654 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
PAMDGHLD_01655 8.7e-122 yetF S membrane
PAMDGHLD_01657 1.9e-95 yesJ K Acetyltransferase (GNAT) family
PAMDGHLD_01658 8.9e-104 cotJC P Spore Coat
PAMDGHLD_01659 3.3e-45 cotJB S CotJB protein
PAMDGHLD_01660 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
PAMDGHLD_01661 3.6e-109 aadK G Streptomycin adenylyltransferase
PAMDGHLD_01663 9.4e-127 yeeN K transcriptional regulatory protein
PAMDGHLD_01664 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
PAMDGHLD_01665 2.4e-78 S Protein of unknown function, DUF600
PAMDGHLD_01666 8e-53 S Protein of unknown function, DUF600
PAMDGHLD_01667 1.1e-46 S Protein of unknown function, DUF600
PAMDGHLD_01668 5e-52 S Protein of unknown function, DUF600
PAMDGHLD_01669 3.1e-62 S Protein of unknown function, DUF600
PAMDGHLD_01670 3.8e-138 cylB V ABC-2 type transporter
PAMDGHLD_01671 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
PAMDGHLD_01672 1.9e-310 L Uncharacterized conserved protein (DUF2075)
PAMDGHLD_01673 1.4e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PAMDGHLD_01674 8.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PAMDGHLD_01675 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAMDGHLD_01676 6.9e-153 yerO K Transcriptional regulator
PAMDGHLD_01677 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PAMDGHLD_01678 4.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PAMDGHLD_01679 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PAMDGHLD_01680 4.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAMDGHLD_01681 1.5e-121 sapB S MgtC SapB transporter
PAMDGHLD_01682 1.3e-195 yerI S homoserine kinase type II (protein kinase fold)
PAMDGHLD_01683 3.1e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
PAMDGHLD_01684 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PAMDGHLD_01685 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PAMDGHLD_01686 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PAMDGHLD_01687 2.2e-301 yerD 1.4.7.1 E Belongs to the glutamate synthase family
PAMDGHLD_01688 2.4e-50 yerC S protein conserved in bacteria
PAMDGHLD_01689 3.4e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
PAMDGHLD_01690 0.0 yerA 3.5.4.2 F adenine deaminase
PAMDGHLD_01691 8.9e-26 S Protein of unknown function (DUF2892)
PAMDGHLD_01692 3.7e-235 purD 6.3.4.13 F Belongs to the GARS family
PAMDGHLD_01693 3.9e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PAMDGHLD_01694 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PAMDGHLD_01695 1.9e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PAMDGHLD_01696 6.8e-270 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PAMDGHLD_01697 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAMDGHLD_01698 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAMDGHLD_01699 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAMDGHLD_01700 2.9e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PAMDGHLD_01701 4.7e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PAMDGHLD_01702 3.6e-224 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PAMDGHLD_01703 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PAMDGHLD_01704 6.1e-28 yebG S NETI protein
PAMDGHLD_01705 3.1e-93 yebE S UPF0316 protein
PAMDGHLD_01707 2.1e-127 yebC M Membrane
PAMDGHLD_01708 6.2e-209 pbuG S permease
PAMDGHLD_01709 2.6e-253 S Domain of unknown function (DUF4179)
PAMDGHLD_01710 8.6e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
PAMDGHLD_01711 1.3e-82
PAMDGHLD_01712 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PAMDGHLD_01713 0.0 yebA E COG1305 Transglutaminase-like enzymes
PAMDGHLD_01714 3.4e-214 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PAMDGHLD_01715 8.6e-176 yeaC S COG0714 MoxR-like ATPases
PAMDGHLD_01716 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
PAMDGHLD_01717 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
PAMDGHLD_01718 7.2e-35 ydjO S Cold-inducible protein YdjO
PAMDGHLD_01719 6.2e-07 ydjN U Involved in the tonB-independent uptake of proteins
PAMDGHLD_01720 1e-134 ydjN U Involved in the tonB-independent uptake of proteins
PAMDGHLD_01721 7.1e-62 ydjM M Lytic transglycolase
PAMDGHLD_01722 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
PAMDGHLD_01723 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
PAMDGHLD_01724 1.7e-146 rsiV S Protein of unknown function (DUF3298)
PAMDGHLD_01725 0.0 yrhL I Acyltransferase family
PAMDGHLD_01726 7.6e-151 ydjI S virion core protein (lumpy skin disease virus)
PAMDGHLD_01727 1.3e-118 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
PAMDGHLD_01728 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PAMDGHLD_01729 8.7e-114 pspA KT Phage shock protein A
PAMDGHLD_01730 5.6e-31 yjdJ S Domain of unknown function (DUF4306)
PAMDGHLD_01731 5.4e-170 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
PAMDGHLD_01732 2.6e-250 gutA G MFS/sugar transport protein
PAMDGHLD_01733 1.2e-199 gutB 1.1.1.14 E Dehydrogenase
PAMDGHLD_01734 0.0 K NB-ARC domain
PAMDGHLD_01735 2.1e-75 T helix_turn_helix, Lux Regulon
PAMDGHLD_01736 0.0 V Beta-lactamase
PAMDGHLD_01737 4.7e-92 S Putative sensor
PAMDGHLD_01738 0.0 yvfT T helix_turn_helix, Lux Regulon
PAMDGHLD_01739 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PAMDGHLD_01740 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PAMDGHLD_01741 3.1e-125 ydiL S CAAX protease self-immunity
PAMDGHLD_01742 1.7e-27 ydiK S Domain of unknown function (DUF4305)
PAMDGHLD_01743 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PAMDGHLD_01744 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PAMDGHLD_01745 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PAMDGHLD_01746 3e-87 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PAMDGHLD_01747 0.0 ydiF S ABC transporter
PAMDGHLD_01748 2.3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PAMDGHLD_01749 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PAMDGHLD_01750 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
PAMDGHLD_01751 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
PAMDGHLD_01752 3.7e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PAMDGHLD_01754 7.8e-08
PAMDGHLD_01755 3.4e-39 S COG NOG14552 non supervised orthologous group
PAMDGHLD_01758 3.5e-250 iolT EGP Major facilitator Superfamily
PAMDGHLD_01759 1.8e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
PAMDGHLD_01760 6.6e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
PAMDGHLD_01761 3.5e-165 ydhU P Catalase
PAMDGHLD_01762 9.3e-297 yveA E amino acid
PAMDGHLD_01763 5.3e-104 yvdT K Transcriptional regulator
PAMDGHLD_01764 2.3e-51 ykkC P Small Multidrug Resistance protein
PAMDGHLD_01765 1.3e-48 sugE P Small Multidrug Resistance protein
PAMDGHLD_01766 7.4e-217 yeaN P COG2807 Cyanate permease
PAMDGHLD_01767 1.3e-117 K FCD
PAMDGHLD_01768 1.3e-133 ydhQ K UTRA
PAMDGHLD_01769 4.5e-195 pbuE EGP Major facilitator Superfamily
PAMDGHLD_01770 7.2e-98 ydhK M Protein of unknown function (DUF1541)
PAMDGHLD_01772 8.5e-262 pbpE V Beta-lactamase
PAMDGHLD_01775 6.4e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PAMDGHLD_01776 5.3e-119 ydhC K FCD
PAMDGHLD_01777 3.4e-165 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
PAMDGHLD_01778 2.9e-145 ycgJ_1 Q ubiE/COQ5 methyltransferase family
PAMDGHLD_01779 1e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
PAMDGHLD_01780 6.9e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PAMDGHLD_01781 7.6e-149 bltR K helix_turn_helix, mercury resistance
PAMDGHLD_01782 1.3e-81 bltD 2.3.1.57 K FR47-like protein
PAMDGHLD_01783 6.5e-123 ydhB S membrane transporter protein
PAMDGHLD_01784 2.5e-155 K Helix-turn-helix XRE-family like proteins
PAMDGHLD_01785 3.2e-223 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PAMDGHLD_01786 9.7e-209 tcaB EGP Major facilitator Superfamily
PAMDGHLD_01787 2.3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
PAMDGHLD_01788 1.8e-148 S Uncharacterized protein conserved in bacteria (DUF2179)
PAMDGHLD_01789 1.8e-98 ynaD J Acetyltransferase (GNAT) domain
PAMDGHLD_01790 1.6e-299 expZ S ABC transporter
PAMDGHLD_01791 8e-134 puuD S Peptidase C26
PAMDGHLD_01792 0.0 ydfJ S drug exporters of the RND superfamily
PAMDGHLD_01793 1.6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAMDGHLD_01794 9.5e-215 ydfH 2.7.13.3 T Histidine kinase
PAMDGHLD_01795 3.4e-36 yraG
PAMDGHLD_01796 6.4e-63 yraF M Spore coat protein
PAMDGHLD_01797 4.2e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PAMDGHLD_01798 1.1e-24 yraE
PAMDGHLD_01799 9.5e-49 yraD M Spore coat protein
PAMDGHLD_01800 4e-267 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PAMDGHLD_01801 4.1e-156 ydeK EG -transporter
PAMDGHLD_01802 4.5e-103 ydeS K Transcriptional regulator
PAMDGHLD_01803 3.8e-181 ydeR EGP Major facilitator Superfamily
PAMDGHLD_01805 7.1e-115 paiB K Transcriptional regulator
PAMDGHLD_01806 2.4e-264 K helix_turn_helix gluconate operon transcriptional repressor
PAMDGHLD_01807 1.8e-221 mleN_2 C antiporter
PAMDGHLD_01808 8.9e-66 yraB K helix_turn_helix, mercury resistance
PAMDGHLD_01809 1.3e-201 adhA 1.1.1.1 C alcohol dehydrogenase
PAMDGHLD_01810 1.1e-165 S Sodium Bile acid symporter family
PAMDGHLD_01811 1.5e-51 ydeH
PAMDGHLD_01812 4.6e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
PAMDGHLD_01814 2.9e-28 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
PAMDGHLD_01815 3.4e-29 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
PAMDGHLD_01816 2.6e-75 ykkA S Protein of unknown function (DUF664)
PAMDGHLD_01817 1e-101 yrkC G Cupin domain
PAMDGHLD_01819 1.1e-197 trkA P Oxidoreductase
PAMDGHLD_01820 4.6e-166 czcD P COG1230 Co Zn Cd efflux system component
PAMDGHLD_01821 1.3e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
PAMDGHLD_01823 1.2e-61 G Cupin domain
PAMDGHLD_01824 4.1e-78 S DinB superfamily
PAMDGHLD_01825 4.7e-182 S Patatin-like phospholipase
PAMDGHLD_01826 3.4e-52 K Transcriptional regulator PadR-like family
PAMDGHLD_01827 1.7e-102 S Protein of unknown function (DUF2812)
PAMDGHLD_01828 3.6e-120 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PAMDGHLD_01829 2.3e-118 yrkJ S membrane transporter protein
PAMDGHLD_01830 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
PAMDGHLD_01831 7.9e-197 yrkH P Rhodanese Homology Domain
PAMDGHLD_01832 8.5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
PAMDGHLD_01833 1.6e-58 P Rhodanese Homology Domain
PAMDGHLD_01834 1.4e-81 yrkE O DsrE/DsrF/DrsH-like family
PAMDGHLD_01835 4.6e-39 yrkD S protein conserved in bacteria
PAMDGHLD_01836 1.4e-78 carD K Transcription factor
PAMDGHLD_01837 1.4e-30 cspL K Cold shock
PAMDGHLD_01838 1.1e-189 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
PAMDGHLD_01839 3.8e-111 ywnB S NAD(P)H-binding
PAMDGHLD_01840 3.3e-74 ywnA K Transcriptional regulator
PAMDGHLD_01841 3.8e-65 yyaQ S YjbR
PAMDGHLD_01842 2.1e-73 maoC I N-terminal half of MaoC dehydratase
PAMDGHLD_01843 4.2e-71 S Domain of unknown function with cystatin-like fold (DUF4467)
PAMDGHLD_01844 4.5e-49 ohrR K Transcriptional regulator
PAMDGHLD_01845 6.1e-231 proP EGP Transporter
PAMDGHLD_01847 8.8e-139 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PAMDGHLD_01848 1.8e-42
PAMDGHLD_01850 1.7e-122 S ATPase (AAA superfamily
PAMDGHLD_01859 1.1e-56 ydcK S Belongs to the SprT family
PAMDGHLD_01860 1.7e-14
PAMDGHLD_01861 0.0 yhgF K COG2183 Transcriptional accessory protein
PAMDGHLD_01862 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
PAMDGHLD_01863 1.8e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAMDGHLD_01864 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PAMDGHLD_01865 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
PAMDGHLD_01866 1.7e-187 rsbU 3.1.3.3 KT phosphatase
PAMDGHLD_01867 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PAMDGHLD_01868 1.8e-57 rsbS T antagonist
PAMDGHLD_01869 6.1e-146 rsbR T Positive regulator of sigma-B
PAMDGHLD_01870 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
PAMDGHLD_01871 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PAMDGHLD_01872 1.4e-217 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PAMDGHLD_01873 7.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
PAMDGHLD_01874 2.3e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PAMDGHLD_01875 3.1e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
PAMDGHLD_01876 2.8e-263 ydbT S Membrane
PAMDGHLD_01877 3.6e-82 ydbS S Bacterial PH domain
PAMDGHLD_01878 9.9e-248 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PAMDGHLD_01879 8.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PAMDGHLD_01880 6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PAMDGHLD_01881 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PAMDGHLD_01882 5.8e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAMDGHLD_01883 5.8e-09 S Fur-regulated basic protein A
PAMDGHLD_01884 1.5e-10 S Fur-regulated basic protein B
PAMDGHLD_01885 2.9e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
PAMDGHLD_01886 1.3e-51 ydbL
PAMDGHLD_01887 9.7e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PAMDGHLD_01888 1.1e-172 ydbJ V ABC transporter, ATP-binding protein
PAMDGHLD_01889 3.2e-160 ydbI S AI-2E family transporter
PAMDGHLD_01890 5e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PAMDGHLD_01891 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
PAMDGHLD_01892 7.9e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PAMDGHLD_01893 2.1e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PAMDGHLD_01894 4.2e-155 ydbD P Catalase
PAMDGHLD_01895 1.3e-60 ydbC S Domain of unknown function (DUF4937
PAMDGHLD_01896 3.4e-58 ydbB G Cupin domain
PAMDGHLD_01898 7.5e-141 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
PAMDGHLD_01899 7e-54 yvaE P Small Multidrug Resistance protein
PAMDGHLD_01900 3.2e-71 yvaD S Family of unknown function (DUF5360)
PAMDGHLD_01901 6.5e-34 ydaT
PAMDGHLD_01903 2e-225 mntH P H( )-stimulated, divalent metal cation uptake system
PAMDGHLD_01904 2.1e-39
PAMDGHLD_01905 4.8e-97
PAMDGHLD_01906 7.4e-79
PAMDGHLD_01908 6.1e-11
PAMDGHLD_01910 1e-207 S Histidine kinase
PAMDGHLD_01912 1.8e-69
PAMDGHLD_01913 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PAMDGHLD_01914 1.8e-57 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PAMDGHLD_01915 0.0 ydaO E amino acid
PAMDGHLD_01916 0.0 ydaN S Bacterial cellulose synthase subunit
PAMDGHLD_01917 3.6e-230 ydaM M Glycosyl transferase family group 2
PAMDGHLD_01918 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
PAMDGHLD_01919 5.1e-148 ydaK T Diguanylate cyclase, GGDEF domain
PAMDGHLD_01920 2.5e-200 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
PAMDGHLD_01921 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PAMDGHLD_01922 4.3e-74 lrpC K Transcriptional regulator
PAMDGHLD_01923 1.3e-47 ydzA EGP Major facilitator Superfamily
PAMDGHLD_01924 1.3e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PAMDGHLD_01925 1.4e-77 ydaG 1.4.3.5 S general stress protein
PAMDGHLD_01926 1.5e-112 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PAMDGHLD_01927 2.3e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
PAMDGHLD_01928 9.7e-163 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAMDGHLD_01929 8.5e-287 ydaB IQ acyl-CoA ligase
PAMDGHLD_01930 0.0 mtlR K transcriptional regulator, MtlR
PAMDGHLD_01931 3.4e-174 ydhF S Oxidoreductase
PAMDGHLD_01932 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
PAMDGHLD_01933 5.1e-56 yczJ S biosynthesis
PAMDGHLD_01935 1.8e-116 ycsK E anatomical structure formation involved in morphogenesis
PAMDGHLD_01936 4.9e-129 kipR K Transcriptional regulator
PAMDGHLD_01937 4.9e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
PAMDGHLD_01938 5.1e-136 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
PAMDGHLD_01939 2.5e-149 ycsI S Belongs to the D-glutamate cyclase family
PAMDGHLD_01940 2.3e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
PAMDGHLD_01941 1.5e-138 ycsF S Belongs to the UPF0271 (lamB) family
PAMDGHLD_01942 2.3e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PAMDGHLD_01944 2.5e-65 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
PAMDGHLD_01945 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
PAMDGHLD_01946 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
PAMDGHLD_01947 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
PAMDGHLD_01948 6e-55
PAMDGHLD_01949 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
PAMDGHLD_01950 5.2e-298 ycnJ P protein, homolog of Cu resistance protein CopC
PAMDGHLD_01951 7.8e-98 ycnI S protein conserved in bacteria
PAMDGHLD_01952 1.9e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAMDGHLD_01953 3.6e-149 glcU U Glucose uptake
PAMDGHLD_01954 2.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PAMDGHLD_01955 4.5e-220 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAMDGHLD_01956 2.1e-263 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PAMDGHLD_01957 2.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
PAMDGHLD_01958 2.3e-44 ycnE S Monooxygenase
PAMDGHLD_01959 2.6e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
PAMDGHLD_01960 2.1e-152 ycnC K Transcriptional regulator
PAMDGHLD_01961 1.6e-247 ycnB EGP Major facilitator Superfamily
PAMDGHLD_01962 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
PAMDGHLD_01963 3.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
PAMDGHLD_01964 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAMDGHLD_01965 5.2e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAMDGHLD_01966 3.2e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
PAMDGHLD_01968 1.9e-81 S aspartate phosphatase
PAMDGHLD_01969 1.5e-261 T PhoQ Sensor
PAMDGHLD_01970 5.2e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_01971 2.5e-232 yclI V ABC transporter (permease) YclI
PAMDGHLD_01972 2.7e-123 yclH P ABC transporter
PAMDGHLD_01973 6.7e-251 yxeQ S MmgE/PrpD family
PAMDGHLD_01974 5.4e-217 yxeP 3.5.1.47 E hydrolase activity
PAMDGHLD_01975 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
PAMDGHLD_01976 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
PAMDGHLD_01977 3e-142 yxeM M Belongs to the bacterial solute-binding protein 3 family
PAMDGHLD_01978 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAMDGHLD_01979 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAMDGHLD_01980 1.9e-195 gerKB F Spore germination protein
PAMDGHLD_01981 1.4e-234 gerKC S spore germination
PAMDGHLD_01982 5e-285 gerKA EG Spore germination protein
PAMDGHLD_01984 4.6e-276 yclG M Pectate lyase superfamily protein
PAMDGHLD_01985 7e-270 dtpT E amino acid peptide transporter
PAMDGHLD_01986 1.7e-76 yclD
PAMDGHLD_01987 2e-38 bsdD 4.1.1.61 S response to toxic substance
PAMDGHLD_01988 1.4e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
PAMDGHLD_01989 2.1e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PAMDGHLD_01990 6.6e-159 bsdA K LysR substrate binding domain
PAMDGHLD_01991 2.7e-92 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PAMDGHLD_01992 3.2e-119 tcyB P COG0765 ABC-type amino acid transport system, permease component
PAMDGHLD_01993 3.4e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PAMDGHLD_01994 1.3e-111 yczE S membrane
PAMDGHLD_01995 1e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
PAMDGHLD_01996 1.8e-248 bamJ E Aminotransferase class I and II
PAMDGHLD_01997 1.3e-139 srfAD Q thioesterase
PAMDGHLD_01998 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
PAMDGHLD_01999 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_02000 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_02001 6.3e-63 hxlR K transcriptional
PAMDGHLD_02002 2.8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
PAMDGHLD_02003 1.2e-92 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
PAMDGHLD_02004 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
PAMDGHLD_02005 8.5e-69 nin S Competence protein J (ComJ)
PAMDGHLD_02006 2.6e-35 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PAMDGHLD_02007 4.9e-51 S Protein of unknown function (DUF2680)
PAMDGHLD_02008 4.7e-73 yckC S membrane
PAMDGHLD_02009 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PAMDGHLD_02010 4.9e-229 yciC S GTPases (G3E family)
PAMDGHLD_02011 3.1e-223 nasA P COG2223 Nitrate nitrite transporter
PAMDGHLD_02012 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
PAMDGHLD_02013 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAMDGHLD_02014 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PAMDGHLD_02015 1.7e-56 nirD 1.7.1.15 P Nitrite reductase
PAMDGHLD_02016 2.8e-279 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
PAMDGHLD_02017 6.4e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PAMDGHLD_02018 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
PAMDGHLD_02019 2.9e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PAMDGHLD_02020 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
PAMDGHLD_02021 2.3e-170 ycgM E Proline dehydrogenase
PAMDGHLD_02022 4.2e-141 ycgL S Predicted nucleotidyltransferase
PAMDGHLD_02023 1.9e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
PAMDGHLD_02024 7.4e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PAMDGHLD_02025 1e-219 G COG0477 Permeases of the major facilitator superfamily
PAMDGHLD_02026 1.4e-147 4.2.1.118 G Xylose isomerase-like TIM barrel
PAMDGHLD_02027 1.3e-108 tmrB S AAA domain
PAMDGHLD_02029 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PAMDGHLD_02030 7.6e-114 ycgI S Domain of unknown function (DUF1989)
PAMDGHLD_02031 2.2e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
PAMDGHLD_02032 1.7e-150 yqcI S YqcI/YcgG family
PAMDGHLD_02033 4.7e-114 ycgF E Lysine exporter protein LysE YggA
PAMDGHLD_02034 1.8e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
PAMDGHLD_02035 1.2e-259 mdr EGP Major facilitator Superfamily
PAMDGHLD_02036 1.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PAMDGHLD_02037 8.2e-27 amyE 3.2.1.1 GH13 G alpha-amylase
PAMDGHLD_02038 3e-273 amyE 3.2.1.1 GH13 G alpha-amylase
PAMDGHLD_02039 3.1e-81 ycgB
PAMDGHLD_02040 1.1e-230 ycgA S Membrane
PAMDGHLD_02041 3.3e-211 amhX S amidohydrolase
PAMDGHLD_02042 6.9e-164 opuAC E glycine betaine
PAMDGHLD_02043 1.6e-138 opuAB P glycine betaine
PAMDGHLD_02044 4.3e-228 proV 3.6.3.32 E glycine betaine
PAMDGHLD_02045 1.8e-215 naiP P Uncharacterised MFS-type transporter YbfB
PAMDGHLD_02046 8.7e-193 yceH P Belongs to the TelA family
PAMDGHLD_02047 0.0 yceG S Putative component of 'biosynthetic module'
PAMDGHLD_02048 9.7e-138 terC P Protein of unknown function (DUF475)
PAMDGHLD_02049 2.3e-107 yceE T proteins involved in stress response, homologs of TerZ and
PAMDGHLD_02050 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
PAMDGHLD_02051 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
PAMDGHLD_02052 1.2e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAMDGHLD_02053 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PAMDGHLD_02054 7.2e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PAMDGHLD_02055 6e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
PAMDGHLD_02056 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
PAMDGHLD_02057 8.9e-139 IQ Enoyl-(Acyl carrier protein) reductase
PAMDGHLD_02058 1.3e-188 S response regulator aspartate phosphatase
PAMDGHLD_02059 1.4e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
PAMDGHLD_02060 1.8e-264 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
PAMDGHLD_02061 1.3e-257 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
PAMDGHLD_02062 5.8e-175 ycdA S Domain of unknown function (DUF5105)
PAMDGHLD_02063 4.2e-101 yccK C Aldo keto reductase
PAMDGHLD_02064 1.9e-54 yccK C Aldo keto reductase
PAMDGHLD_02065 6.4e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
PAMDGHLD_02066 1.3e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
PAMDGHLD_02067 3.9e-196 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PAMDGHLD_02068 1.3e-99 yxaF K Transcriptional regulator
PAMDGHLD_02069 2.5e-240 lmrB EGP the major facilitator superfamily
PAMDGHLD_02070 2.5e-206 ycbU E Selenocysteine lyase
PAMDGHLD_02071 1.2e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PAMDGHLD_02072 4.7e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PAMDGHLD_02073 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PAMDGHLD_02074 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
PAMDGHLD_02075 2e-76 sleB 3.5.1.28 M Cell wall
PAMDGHLD_02076 5.6e-62 ycbP S Protein of unknown function (DUF2512)
PAMDGHLD_02077 1.3e-54 traF CO Thioredoxin
PAMDGHLD_02078 1.5e-62 mhqP S DoxX
PAMDGHLD_02079 4.1e-183 ydfO E COG0346 Lactoylglutathione lyase and related lyases
PAMDGHLD_02080 6.9e-110 ydfN C nitroreductase
PAMDGHLD_02081 1e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAMDGHLD_02082 1.8e-25 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
PAMDGHLD_02083 3.9e-16 ycbJ S Macrolide 2'-phosphotransferase
PAMDGHLD_02084 1.9e-172 glnL T Regulator
PAMDGHLD_02085 2.2e-211 phoQ 2.7.13.3 T Histidine kinase
PAMDGHLD_02086 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
PAMDGHLD_02087 4.6e-258 agcS E Sodium alanine symporter
PAMDGHLD_02088 1.3e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
PAMDGHLD_02089 8.8e-257 mmuP E amino acid
PAMDGHLD_02090 7.2e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PAMDGHLD_02091 3.2e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PAMDGHLD_02092 2.3e-192 yceA S Belongs to the UPF0176 family
PAMDGHLD_02093 3e-41 ybfN
PAMDGHLD_02094 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
PAMDGHLD_02095 1.9e-86 ybfM S SNARE associated Golgi protein
PAMDGHLD_02096 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PAMDGHLD_02097 3.4e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PAMDGHLD_02098 2.1e-199 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
PAMDGHLD_02099 3.9e-81 K Helix-turn-helix XRE-family like proteins
PAMDGHLD_02100 1.3e-69 yobL L Belongs to the WXG100 family
PAMDGHLD_02101 1e-139 draG 3.2.2.24 O ADP-ribosylglycohydrolase
PAMDGHLD_02103 2.7e-53 S DNA-sulfur modification-associated
PAMDGHLD_02104 3.2e-22 L DNA-sulfur modification-associated
PAMDGHLD_02105 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
PAMDGHLD_02107 3.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
PAMDGHLD_02108 1.3e-16 S Protein of unknown function (DUF2651)
PAMDGHLD_02109 1.7e-259 glpT G -transporter
PAMDGHLD_02110 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PAMDGHLD_02111 4e-16 S Protein of unknown function (DUF2651)
PAMDGHLD_02112 5.7e-52
PAMDGHLD_02113 1.5e-47 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PAMDGHLD_02114 2.1e-291 ybeC E amino acid
PAMDGHLD_02115 9.2e-40 ybyB
PAMDGHLD_02116 3.6e-107 yqeB
PAMDGHLD_02117 1.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
PAMDGHLD_02118 1.2e-74 S Domain of unknown function (DUF4879)
PAMDGHLD_02119 5.8e-25
PAMDGHLD_02120 1.9e-198 V ABC-2 family transporter protein
PAMDGHLD_02121 4.4e-206 V COG0842 ABC-type multidrug transport system, permease component
PAMDGHLD_02122 3.5e-166 V COG1131 ABC-type multidrug transport system, ATPase component
PAMDGHLD_02123 3.6e-109 KT LuxR family transcriptional regulator
PAMDGHLD_02124 5.5e-198 T COG4585 Signal transduction histidine kinase
PAMDGHLD_02125 3.6e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PAMDGHLD_02126 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
PAMDGHLD_02128 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
PAMDGHLD_02129 6.9e-52 S LrgA family
PAMDGHLD_02130 5e-93 yxaC M effector of murein hydrolase
PAMDGHLD_02131 1.2e-162 dkgB S Aldo/keto reductase family
PAMDGHLD_02132 1.4e-17 dkgB S Aldo/keto reductase family
PAMDGHLD_02133 3e-12 cusA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PAMDGHLD_02134 0.0 V ABC transporter (permease)
PAMDGHLD_02135 3.7e-137 V ABC transporter, ATP-binding protein
PAMDGHLD_02136 1.1e-184 T PhoQ Sensor
PAMDGHLD_02137 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_02138 7.5e-107 S ABC-2 family transporter protein
PAMDGHLD_02139 3.4e-155 V ATPases associated with a variety of cellular activities
PAMDGHLD_02140 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PAMDGHLD_02141 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PAMDGHLD_02142 1.1e-222 ybbR S protein conserved in bacteria
PAMDGHLD_02143 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PAMDGHLD_02144 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PAMDGHLD_02145 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
PAMDGHLD_02151 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
PAMDGHLD_02152 7.7e-85 ybbJ J acetyltransferase
PAMDGHLD_02153 2.6e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PAMDGHLD_02154 1.3e-238 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PAMDGHLD_02155 4.9e-243 yfeW 3.4.16.4 V Belongs to the UPF0214 family
PAMDGHLD_02156 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
PAMDGHLD_02157 1.9e-236 ybbC 3.2.1.52 S protein conserved in bacteria
PAMDGHLD_02158 7.5e-310 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
PAMDGHLD_02159 5.7e-172 feuA P Iron-uptake system-binding protein
PAMDGHLD_02160 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAMDGHLD_02161 4.7e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAMDGHLD_02162 4e-112 ybbA S Putative esterase
PAMDGHLD_02163 2.2e-174 ybaS 1.1.1.58 S Na -dependent transporter
PAMDGHLD_02164 4.3e-224 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
PAMDGHLD_02165 7.1e-200 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
PAMDGHLD_02166 1.7e-179 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
PAMDGHLD_02167 1.8e-245 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAMDGHLD_02168 5e-221 glcP G Major Facilitator Superfamily
PAMDGHLD_02169 3.4e-39 S COG NOG14552 non supervised orthologous group
PAMDGHLD_02172 1.6e-08
PAMDGHLD_02175 3.4e-39 S COG NOG14552 non supervised orthologous group
PAMDGHLD_02176 8.4e-134 pdaB 3.5.1.104 G Polysaccharide deacetylase
PAMDGHLD_02177 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
PAMDGHLD_02178 1.7e-75 gerD
PAMDGHLD_02179 1.5e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PAMDGHLD_02180 1.8e-133 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PAMDGHLD_02181 1.7e-78 ybaK S Protein of unknown function (DUF2521)
PAMDGHLD_02182 1.1e-83 yizA S Damage-inducible protein DinB
PAMDGHLD_02183 8.2e-145 ybaJ Q Methyltransferase domain
PAMDGHLD_02184 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
PAMDGHLD_02185 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PAMDGHLD_02186 6.3e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PAMDGHLD_02187 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAMDGHLD_02188 1.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAMDGHLD_02189 3.3e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAMDGHLD_02190 4.7e-58 rplQ J Ribosomal protein L17
PAMDGHLD_02191 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAMDGHLD_02192 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PAMDGHLD_02193 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PAMDGHLD_02194 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PAMDGHLD_02195 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PAMDGHLD_02196 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
PAMDGHLD_02197 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PAMDGHLD_02198 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PAMDGHLD_02199 1.1e-72 rplO J binds to the 23S rRNA
PAMDGHLD_02200 1.9e-23 rpmD J Ribosomal protein L30
PAMDGHLD_02201 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PAMDGHLD_02202 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PAMDGHLD_02203 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PAMDGHLD_02204 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PAMDGHLD_02205 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PAMDGHLD_02206 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PAMDGHLD_02207 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PAMDGHLD_02208 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PAMDGHLD_02209 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PAMDGHLD_02210 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
PAMDGHLD_02211 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PAMDGHLD_02212 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PAMDGHLD_02213 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PAMDGHLD_02214 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PAMDGHLD_02215 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PAMDGHLD_02216 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PAMDGHLD_02217 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
PAMDGHLD_02218 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PAMDGHLD_02219 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PAMDGHLD_02220 6.4e-187 ybaC 3.4.11.5 S Alpha/beta hydrolase family
PAMDGHLD_02221 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PAMDGHLD_02222 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PAMDGHLD_02223 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PAMDGHLD_02224 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PAMDGHLD_02225 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
PAMDGHLD_02226 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAMDGHLD_02227 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAMDGHLD_02228 5.3e-107 rsmC 2.1.1.172 J Methyltransferase
PAMDGHLD_02229 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PAMDGHLD_02230 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PAMDGHLD_02231 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PAMDGHLD_02232 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PAMDGHLD_02233 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
PAMDGHLD_02234 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PAMDGHLD_02235 8.9e-116 sigH K Belongs to the sigma-70 factor family
PAMDGHLD_02236 4.2e-89 yacP S RNA-binding protein containing a PIN domain
PAMDGHLD_02237 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PAMDGHLD_02238 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PAMDGHLD_02239 4.5e-266 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PAMDGHLD_02240 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
PAMDGHLD_02241 8.1e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PAMDGHLD_02242 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PAMDGHLD_02243 3.6e-123 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PAMDGHLD_02244 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
PAMDGHLD_02245 2.9e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PAMDGHLD_02246 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PAMDGHLD_02247 0.0 clpC O Belongs to the ClpA ClpB family
PAMDGHLD_02248 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PAMDGHLD_02249 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
PAMDGHLD_02250 7.5e-77 ctsR K Belongs to the CtsR family
PAMDGHLD_02251 3.4e-39 S COG NOG14552 non supervised orthologous group
PAMDGHLD_02256 2e-08
PAMDGHLD_02259 1.3e-07
PAMDGHLD_02261 3.4e-39 S COG NOG14552 non supervised orthologous group
PAMDGHLD_02262 1.1e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PAMDGHLD_02263 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PAMDGHLD_02264 5.9e-29 yazB K transcriptional
PAMDGHLD_02265 3.8e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PAMDGHLD_02266 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PAMDGHLD_02267 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PAMDGHLD_02268 1.2e-160 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
PAMDGHLD_02269 2.8e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
PAMDGHLD_02270 5.2e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PAMDGHLD_02271 1.4e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PAMDGHLD_02272 5.1e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
PAMDGHLD_02273 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PAMDGHLD_02274 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PAMDGHLD_02275 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PAMDGHLD_02276 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PAMDGHLD_02277 1.5e-269 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PAMDGHLD_02278 4.7e-185 KLT serine threonine protein kinase
PAMDGHLD_02279 1.4e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
PAMDGHLD_02280 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
PAMDGHLD_02283 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
PAMDGHLD_02284 3.5e-56 divIC D Septum formation initiator
PAMDGHLD_02285 6.8e-91 yabQ S spore cortex biosynthesis protein
PAMDGHLD_02286 1.9e-49 yabP S Sporulation protein YabP
PAMDGHLD_02287 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PAMDGHLD_02288 1.7e-276 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PAMDGHLD_02289 1e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAMDGHLD_02290 6.2e-91 spoVT K stage V sporulation protein
PAMDGHLD_02291 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PAMDGHLD_02292 3.7e-40 yabK S Peptide ABC transporter permease
PAMDGHLD_02293 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PAMDGHLD_02294 5e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PAMDGHLD_02295 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PAMDGHLD_02296 1.6e-247 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PAMDGHLD_02297 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PAMDGHLD_02298 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
PAMDGHLD_02299 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PAMDGHLD_02300 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PAMDGHLD_02301 2.9e-27 sspF S DNA topological change
PAMDGHLD_02302 2.3e-38 veg S protein conserved in bacteria
PAMDGHLD_02303 1.2e-144 yabG S peptidase
PAMDGHLD_02304 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PAMDGHLD_02305 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PAMDGHLD_02306 7.2e-229 rpfB GH23 T protein conserved in bacteria
PAMDGHLD_02307 1.7e-142 tatD L hydrolase, TatD
PAMDGHLD_02308 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PAMDGHLD_02309 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
PAMDGHLD_02310 2e-163 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PAMDGHLD_02311 4.7e-48 yazA L endonuclease containing a URI domain
PAMDGHLD_02312 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
PAMDGHLD_02313 7.7e-37 yabA L Involved in initiation control of chromosome replication
PAMDGHLD_02314 8.8e-145 yaaT S stage 0 sporulation protein
PAMDGHLD_02315 2.4e-181 holB 2.7.7.7 L DNA polymerase III
PAMDGHLD_02316 1.2e-71 yaaR S protein conserved in bacteria
PAMDGHLD_02317 7.5e-55 yaaQ S protein conserved in bacteria
PAMDGHLD_02318 1.5e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PAMDGHLD_02319 1.2e-269 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
PAMDGHLD_02320 2.3e-188 yaaN P Belongs to the TelA family
PAMDGHLD_02321 5.1e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PAMDGHLD_02322 2.2e-30 csfB S Inhibitor of sigma-G Gin
PAMDGHLD_02325 3.4e-39 S COG NOG14552 non supervised orthologous group
PAMDGHLD_02326 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
PAMDGHLD_02327 3.6e-32 yaaL S Protein of unknown function (DUF2508)
PAMDGHLD_02328 5.1e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PAMDGHLD_02329 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PAMDGHLD_02330 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PAMDGHLD_02331 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PAMDGHLD_02332 3.7e-99 yaaI Q COG1335 Amidases related to nicotinamidase
PAMDGHLD_02333 2.1e-209 yaaH M Glycoside Hydrolase Family
PAMDGHLD_02334 5.5e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
PAMDGHLD_02335 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
PAMDGHLD_02336 1.3e-09
PAMDGHLD_02337 3.2e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PAMDGHLD_02338 6.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PAMDGHLD_02339 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PAMDGHLD_02340 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PAMDGHLD_02341 1.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PAMDGHLD_02342 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PAMDGHLD_02343 1.7e-182 yaaC S YaaC-like Protein
PAMDGHLD_02346 3.4e-39 S COG NOG14552 non supervised orthologous group
PAMDGHLD_02347 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PAMDGHLD_02348 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PAMDGHLD_02349 8.1e-38 yaaB S Domain of unknown function (DUF370)
PAMDGHLD_02350 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PAMDGHLD_02351 2.4e-33 yaaA S S4 domain
PAMDGHLD_02352 7.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PAMDGHLD_02353 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PAMDGHLD_02355 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PAMDGHLD_02356 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PAMDGHLD_02357 1e-108 jag S single-stranded nucleic acid binding R3H
PAMDGHLD_02358 1.2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PAMDGHLD_02359 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PAMDGHLD_02360 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PAMDGHLD_02361 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PAMDGHLD_02362 9.2e-136 soj D COG1192 ATPases involved in chromosome partitioning
PAMDGHLD_02363 2.3e-148 spo0J K Belongs to the ParB family
PAMDGHLD_02364 4e-110 yyaC S Sporulation protein YyaC
PAMDGHLD_02365 5.5e-81 4.2.1.103 K FR47-like protein
PAMDGHLD_02366 6.9e-176 yyaD S Membrane
PAMDGHLD_02367 2.3e-33 yyzM S protein conserved in bacteria
PAMDGHLD_02368 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAMDGHLD_02369 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PAMDGHLD_02370 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
PAMDGHLD_02371 4.2e-68 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PAMDGHLD_02372 1.1e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PAMDGHLD_02373 7.4e-106 adaA 3.2.2.21 K Transcriptional regulator
PAMDGHLD_02374 6.4e-99 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PAMDGHLD_02375 9.9e-143 xth 3.1.11.2 L exodeoxyribonuclease III
PAMDGHLD_02376 5.2e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
PAMDGHLD_02377 3.4e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAMDGHLD_02378 6.8e-248 ydjK G Sugar (and other) transporter
PAMDGHLD_02379 1.5e-161 yyaK S CAAX protease self-immunity
PAMDGHLD_02380 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
PAMDGHLD_02383 6.7e-69 ynaF
PAMDGHLD_02384 4e-81
PAMDGHLD_02385 5.5e-30 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
PAMDGHLD_02386 9.4e-132 ydfC EG EamA-like transporter family
PAMDGHLD_02387 7.9e-250 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PAMDGHLD_02388 6e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PAMDGHLD_02389 1.4e-164 K Transcriptional regulator
PAMDGHLD_02390 2.3e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
PAMDGHLD_02391 1.2e-163 eaeH M Domain of Unknown Function (DUF1259)
PAMDGHLD_02392 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
PAMDGHLD_02393 5.6e-77 yybA 2.3.1.57 K transcriptional
PAMDGHLD_02394 5.7e-150 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
PAMDGHLD_02395 9.2e-69 ydgJ K Winged helix DNA-binding domain
PAMDGHLD_02396 1.5e-112 drgA C nitroreductase
PAMDGHLD_02397 2.2e-55 ypaA S Protein of unknown function (DUF1304)
PAMDGHLD_02398 9.3e-159 G Major Facilitator Superfamily
PAMDGHLD_02399 7e-76 dinB S PFAM DinB family protein
PAMDGHLD_02400 6.4e-114 K FCD domain
PAMDGHLD_02401 2.1e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
PAMDGHLD_02402 1.1e-272 sacB 2.4.1.10 GH68 M levansucrase activity
PAMDGHLD_02403 4.4e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PAMDGHLD_02404 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
PAMDGHLD_02405 2.8e-66 ydeP3 K Transcriptional regulator
PAMDGHLD_02406 6.5e-85 cotF M Spore coat protein
PAMDGHLD_02408 4.3e-156 yybS S membrane
PAMDGHLD_02409 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PAMDGHLD_02410 4.9e-73 rplI J binds to the 23S rRNA
PAMDGHLD_02411 1.1e-121 KLT COG0515 Serine threonine protein kinase
PAMDGHLD_02412 1.1e-121 S GlcNAc-PI de-N-acetylase
PAMDGHLD_02413 2.2e-238 M Glycosyltransferase Family 4
PAMDGHLD_02414 5.9e-235 S Carbamoyl-phosphate synthase L chain, ATP binding domain
PAMDGHLD_02415 6.9e-203 S Ecdysteroid kinase
PAMDGHLD_02416 1.3e-240 M Glycosyltransferase Family 4
PAMDGHLD_02417 4.6e-17 yycC K YycC-like protein
PAMDGHLD_02419 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
PAMDGHLD_02420 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PAMDGHLD_02421 2.2e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAMDGHLD_02422 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PAMDGHLD_02427 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_02428 0.0 vicK 2.7.13.3 T Histidine kinase
PAMDGHLD_02429 1e-259 yycH S protein conserved in bacteria
PAMDGHLD_02430 8.3e-151 yycI S protein conserved in bacteria
PAMDGHLD_02431 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PAMDGHLD_02432 1.2e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAMDGHLD_02433 9.6e-11 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_02434 4.9e-252 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
PAMDGHLD_02435 2.2e-190 2.7.7.73, 2.7.7.80 H ThiF family
PAMDGHLD_02436 1.2e-260
PAMDGHLD_02437 2.6e-198 S Major Facilitator Superfamily
PAMDGHLD_02438 3e-306 S ABC transporter
PAMDGHLD_02439 9e-146 1.14.11.27 P peptidyl-arginine hydroxylation
PAMDGHLD_02440 1.2e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PAMDGHLD_02441 9.8e-43 sdpR K transcriptional
PAMDGHLD_02442 2.5e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
PAMDGHLD_02443 1.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
PAMDGHLD_02444 6.9e-259 rocE E amino acid
PAMDGHLD_02445 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
PAMDGHLD_02446 5.2e-201 S Histidine kinase
PAMDGHLD_02448 8.2e-87 yycN 2.3.1.128 K Acetyltransferase
PAMDGHLD_02449 1.9e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
PAMDGHLD_02450 1.2e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PAMDGHLD_02451 1.3e-215 yycP
PAMDGHLD_02453 7.9e-08 S YyzF-like protein
PAMDGHLD_02454 2.6e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PAMDGHLD_02455 8e-95 K NAD+ binding
PAMDGHLD_02456 1.1e-80 F 5-carbamoylmethyl uridine residue modification
PAMDGHLD_02457 0.0 L AAA domain
PAMDGHLD_02458 2.1e-17
PAMDGHLD_02459 3.6e-177 S Fusaric acid resistance protein-like
PAMDGHLD_02460 9.7e-186 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PAMDGHLD_02461 3.8e-92 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
PAMDGHLD_02462 6e-64 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PAMDGHLD_02463 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PAMDGHLD_02464 1.2e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
PAMDGHLD_02465 1.3e-84 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
PAMDGHLD_02466 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
PAMDGHLD_02467 1.4e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
PAMDGHLD_02468 5e-229 XK27_00240 S Fic/DOC family
PAMDGHLD_02469 2.3e-287 ahpF O Alkyl hydroperoxide reductase
PAMDGHLD_02470 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
PAMDGHLD_02471 6.4e-125 E Ring-cleavage extradiol dioxygenase
PAMDGHLD_02472 7.6e-74 yxaI S membrane protein domain
PAMDGHLD_02473 5e-202 EGP Major facilitator Superfamily
PAMDGHLD_02474 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
PAMDGHLD_02475 2.7e-65 S Family of unknown function (DUF5391)
PAMDGHLD_02476 4.4e-140 S PQQ-like domain
PAMDGHLD_02477 1.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
PAMDGHLD_02478 1.6e-216 yxbF K Bacterial regulatory proteins, tetR family
PAMDGHLD_02479 4.2e-200 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
PAMDGHLD_02480 4.1e-201 desK 2.7.13.3 T Histidine kinase
PAMDGHLD_02481 7.9e-103 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAMDGHLD_02482 5.3e-150 IQ Enoyl-(Acyl carrier protein) reductase
PAMDGHLD_02484 0.0 htpG O Molecular chaperone. Has ATPase activity
PAMDGHLD_02485 1.9e-245 csbC EGP Major facilitator Superfamily
PAMDGHLD_02486 6e-174 iolS C Aldo keto reductase
PAMDGHLD_02487 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
PAMDGHLD_02488 2.3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PAMDGHLD_02489 2.4e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PAMDGHLD_02490 1.2e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PAMDGHLD_02491 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PAMDGHLD_02492 1.4e-175 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PAMDGHLD_02493 4.3e-231 iolF EGP Major facilitator Superfamily
PAMDGHLD_02494 3.6e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PAMDGHLD_02495 4.3e-166 iolH G Xylose isomerase-like TIM barrel
PAMDGHLD_02496 6e-141 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
PAMDGHLD_02497 5.1e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
PAMDGHLD_02498 6.6e-128 S ABC-2 family transporter protein
PAMDGHLD_02499 3.3e-130 S permease
PAMDGHLD_02500 9.3e-164 bcrA V ABC transporter, ATP-binding protein
PAMDGHLD_02501 8.5e-136 T Transcriptional regulator
PAMDGHLD_02502 2.5e-272 T Histidine kinase
PAMDGHLD_02503 7.9e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_02504 3.3e-175 T PhoQ Sensor
PAMDGHLD_02505 9.4e-141 yxdL V ABC transporter, ATP-binding protein
PAMDGHLD_02506 0.0 yxdM V ABC transporter (permease)
PAMDGHLD_02507 1.3e-57 yxeA S Protein of unknown function (DUF1093)
PAMDGHLD_02508 1.9e-175 fhuD P Periplasmic binding protein
PAMDGHLD_02509 8.6e-12
PAMDGHLD_02511 1.4e-07 yxeE
PAMDGHLD_02514 4e-150 yidA S hydrolases of the HAD superfamily
PAMDGHLD_02515 8.1e-171 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PAMDGHLD_02516 2.7e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PAMDGHLD_02517 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PAMDGHLD_02518 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
PAMDGHLD_02519 3.3e-248 lysP E amino acid
PAMDGHLD_02520 7.9e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
PAMDGHLD_02521 1.5e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
PAMDGHLD_02522 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PAMDGHLD_02523 1.5e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
PAMDGHLD_02524 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
PAMDGHLD_02525 3.3e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
PAMDGHLD_02526 1.7e-09
PAMDGHLD_02527 5.1e-181 L AlwI restriction endonuclease
PAMDGHLD_02528 1.4e-182 2.1.1.37 H C-5 cytosine-specific DNA methylase
PAMDGHLD_02529 2e-44 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
PAMDGHLD_02530 1.1e-13 S Domain of unknown function (DUF5082)
PAMDGHLD_02531 1.8e-102 L Replication protein
PAMDGHLD_02532 9e-25
PAMDGHLD_02534 1.2e-34 K Transcriptional regulator
PAMDGHLD_02537 7e-72 yxiE T Belongs to the universal stress protein A family
PAMDGHLD_02538 3.6e-147 yxxF EG EamA-like transporter family
PAMDGHLD_02539 2.1e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
PAMDGHLD_02540 1.5e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
PAMDGHLD_02541 1.1e-220 yxiO S COG2270 Permeases of the major facilitator superfamily
PAMDGHLD_02542 2.3e-141 exoK GH16 M licheninase activity
PAMDGHLD_02543 2.8e-222 citH C Citrate transporter
PAMDGHLD_02544 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
PAMDGHLD_02545 1.4e-50 yxiS
PAMDGHLD_02546 3.9e-74 T Domain of unknown function (DUF4163)
PAMDGHLD_02547 8.6e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PAMDGHLD_02548 3.3e-127 rlmA 2.1.1.187 Q Methyltransferase domain
PAMDGHLD_02549 2.8e-218 yxjG 2.1.1.14 E Methionine synthase
PAMDGHLD_02550 1.2e-85 yxjI S LURP-one-related
PAMDGHLD_02553 1.9e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PAMDGHLD_02554 1.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PAMDGHLD_02555 3.8e-87 yxkC S Domain of unknown function (DUF4352)
PAMDGHLD_02556 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAMDGHLD_02557 7.7e-163 lrp QT PucR C-terminal helix-turn-helix domain
PAMDGHLD_02558 7e-206 msmK P Belongs to the ABC transporter superfamily
PAMDGHLD_02559 1.3e-156 yxkH G Polysaccharide deacetylase
PAMDGHLD_02560 2.9e-214 cimH C COG3493 Na citrate symporter
PAMDGHLD_02561 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
PAMDGHLD_02562 4.6e-188 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
PAMDGHLD_02563 0.0 cydD V ATP-binding
PAMDGHLD_02564 5.9e-292 cydD V ATP-binding protein
PAMDGHLD_02565 7.7e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PAMDGHLD_02566 2.8e-59 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PAMDGHLD_02567 9.6e-105 natA V ATPases associated with a variety of cellular activities
PAMDGHLD_02569 2.1e-41 T LytTr DNA-binding domain
PAMDGHLD_02572 1.3e-99 V AAA domain, putative AbiEii toxin, Type IV TA system
PAMDGHLD_02574 5.5e-248 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
PAMDGHLD_02575 4.2e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PAMDGHLD_02576 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PAMDGHLD_02577 1.3e-209 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
PAMDGHLD_02578 2.4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
PAMDGHLD_02579 1.5e-23 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
PAMDGHLD_02580 1e-109 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
PAMDGHLD_02581 2.1e-287 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PAMDGHLD_02582 9.2e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAMDGHLD_02583 3.5e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
PAMDGHLD_02584 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
PAMDGHLD_02585 2.9e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PAMDGHLD_02586 5e-57 arsR K transcriptional
PAMDGHLD_02587 2e-166 cbrA3 P Periplasmic binding protein
PAMDGHLD_02588 1.3e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAMDGHLD_02589 2.8e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAMDGHLD_02590 3.8e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PAMDGHLD_02591 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
PAMDGHLD_02592 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
PAMDGHLD_02593 3.3e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAMDGHLD_02594 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
PAMDGHLD_02595 4.6e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PAMDGHLD_02596 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PAMDGHLD_02597 2.9e-226 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PAMDGHLD_02598 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_02599 3.7e-229 dltB M membrane protein involved in D-alanine export
PAMDGHLD_02600 3.5e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_02601 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
PAMDGHLD_02602 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
PAMDGHLD_02603 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
PAMDGHLD_02604 4.4e-163 gspA M General stress
PAMDGHLD_02605 2.3e-264 epr 3.4.21.62 O Belongs to the peptidase S8 family
PAMDGHLD_02606 1.6e-244 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAMDGHLD_02607 4.5e-67 ywbC 4.4.1.5 E glyoxalase
PAMDGHLD_02608 8e-224 ywbD 2.1.1.191 J Methyltransferase
PAMDGHLD_02609 2.5e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
PAMDGHLD_02610 2e-135 mta K transcriptional
PAMDGHLD_02611 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
PAMDGHLD_02612 1.5e-110 ywbG M effector of murein hydrolase
PAMDGHLD_02613 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PAMDGHLD_02614 8.2e-152 ywbI K Transcriptional regulator
PAMDGHLD_02615 5.3e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PAMDGHLD_02616 2.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PAMDGHLD_02617 1.5e-241 ywbN P Dyp-type peroxidase family protein
PAMDGHLD_02618 5.5e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PAMDGHLD_02619 2.9e-130 S Streptomycin biosynthesis protein StrF
PAMDGHLD_02620 3.6e-128 H Methionine biosynthesis protein MetW
PAMDGHLD_02622 8.7e-113 ywcC K Bacterial regulatory proteins, tetR family
PAMDGHLD_02623 1.7e-61 gtcA S GtrA-like protein
PAMDGHLD_02624 2.7e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PAMDGHLD_02625 9.2e-297 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PAMDGHLD_02626 8.4e-27 ywzA S membrane
PAMDGHLD_02627 1.4e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PAMDGHLD_02628 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PAMDGHLD_02629 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
PAMDGHLD_02630 9.9e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
PAMDGHLD_02631 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
PAMDGHLD_02632 1e-77 ysnE K acetyltransferase
PAMDGHLD_02633 9.8e-214 rodA D Belongs to the SEDS family
PAMDGHLD_02634 3.6e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
PAMDGHLD_02635 4e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAMDGHLD_02636 0.0 vpr O Belongs to the peptidase S8 family
PAMDGHLD_02638 1.3e-151 sacT K transcriptional antiterminator
PAMDGHLD_02639 6.2e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PAMDGHLD_02640 1.3e-284 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
PAMDGHLD_02641 9.7e-20 ywdA
PAMDGHLD_02642 3.9e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PAMDGHLD_02643 3.1e-56 pex K Transcriptional regulator PadR-like family
PAMDGHLD_02644 6.9e-14 ywdD
PAMDGHLD_02645 2.6e-64 ywdD
PAMDGHLD_02647 2.1e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
PAMDGHLD_02648 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PAMDGHLD_02649 8.8e-40 ywdI S Family of unknown function (DUF5327)
PAMDGHLD_02650 2.4e-229 ywdJ F Xanthine uracil
PAMDGHLD_02651 4.2e-46 ywdK S small membrane protein
PAMDGHLD_02652 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PAMDGHLD_02653 7.7e-143 spsA M Spore Coat
PAMDGHLD_02654 7e-275 spsB M Capsule polysaccharide biosynthesis protein
PAMDGHLD_02655 9.6e-222 spsC E Belongs to the DegT DnrJ EryC1 family
PAMDGHLD_02656 1.7e-159 spsD 2.3.1.210 K Spore Coat
PAMDGHLD_02657 3.8e-215 spsE 2.5.1.56 M acid synthase
PAMDGHLD_02658 2.4e-133 spsF M Spore Coat
PAMDGHLD_02659 1.5e-183 spsG M Spore Coat
PAMDGHLD_02660 2.7e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PAMDGHLD_02661 6.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PAMDGHLD_02662 5.8e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PAMDGHLD_02663 3.5e-87 spsL 5.1.3.13 M Spore Coat
PAMDGHLD_02664 3.3e-172 bcrA5 V ABC transporter, ATP-binding protein
PAMDGHLD_02665 2.9e-120 S ABC-2 family transporter protein
PAMDGHLD_02666 2.9e-74
PAMDGHLD_02667 1.5e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_02668 9.3e-159 T PhoQ Sensor
PAMDGHLD_02669 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
PAMDGHLD_02670 1.7e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
PAMDGHLD_02671 0.0 rocB E arginine degradation protein
PAMDGHLD_02672 3.1e-259 lysP E amino acid
PAMDGHLD_02673 4e-207 tcaB EGP Major facilitator Superfamily
PAMDGHLD_02674 9.2e-223 ywfA EGP Major facilitator Superfamily
PAMDGHLD_02675 9.5e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
PAMDGHLD_02676 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
PAMDGHLD_02677 5.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAMDGHLD_02678 1.8e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
PAMDGHLD_02679 4.7e-208 bacE EGP Major facilitator Superfamily
PAMDGHLD_02680 7.8e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
PAMDGHLD_02681 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
PAMDGHLD_02682 1.1e-146 ywfI C May function as heme-dependent peroxidase
PAMDGHLD_02683 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
PAMDGHLD_02684 1.8e-157 MA20_14895 S Conserved hypothetical protein 698
PAMDGHLD_02685 6.6e-162 cysL K Transcriptional regulator
PAMDGHLD_02686 1.1e-158 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PAMDGHLD_02688 3.6e-182
PAMDGHLD_02691 1e-148 yhcI S ABC transporter (permease)
PAMDGHLD_02692 3.8e-165 V ABC transporter, ATP-binding protein
PAMDGHLD_02693 5.2e-93 S membrane
PAMDGHLD_02694 8.2e-51 padR K PadR family transcriptional regulator
PAMDGHLD_02695 3e-110 rsfA_1
PAMDGHLD_02696 6.9e-36 ywzC S Belongs to the UPF0741 family
PAMDGHLD_02697 6.7e-256 ywfO S COG1078 HD superfamily phosphohydrolases
PAMDGHLD_02698 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
PAMDGHLD_02699 3.5e-247 yhdG_1 E C-terminus of AA_permease
PAMDGHLD_02700 8e-70 ywhA K Transcriptional regulator
PAMDGHLD_02701 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
PAMDGHLD_02702 1.2e-117 ywhC S Peptidase family M50
PAMDGHLD_02703 4e-95 ywhD S YwhD family
PAMDGHLD_02704 2.9e-10
PAMDGHLD_02705 1e-53
PAMDGHLD_02706 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PAMDGHLD_02707 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PAMDGHLD_02708 3.5e-168 speB 3.5.3.11 E Belongs to the arginase family
PAMDGHLD_02710 7.5e-78 S aspartate phosphatase
PAMDGHLD_02711 6.8e-219 ywhK CO amine dehydrogenase activity
PAMDGHLD_02712 2.6e-226 ywhL CO amine dehydrogenase activity
PAMDGHLD_02714 8.8e-72 ywiB S protein conserved in bacteria
PAMDGHLD_02715 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PAMDGHLD_02716 1.3e-213 narK P COG2223 Nitrate nitrite transporter
PAMDGHLD_02717 1e-128 fnr K helix_turn_helix, cAMP Regulatory protein
PAMDGHLD_02718 4.2e-17 ywiC S YwiC-like protein
PAMDGHLD_02719 1.3e-84 arfM T cyclic nucleotide binding
PAMDGHLD_02720 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAMDGHLD_02721 9e-294 narH 1.7.5.1 C Nitrate reductase, beta
PAMDGHLD_02722 3.6e-94 narJ 1.7.5.1 C nitrate reductase
PAMDGHLD_02723 2e-123 narI 1.7.5.1 C nitrate reductase, gamma
PAMDGHLD_02724 1.4e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAMDGHLD_02725 1.6e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAMDGHLD_02726 0.0 ywjA V ABC transporter
PAMDGHLD_02727 4.2e-43 ywjC
PAMDGHLD_02728 6.1e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
PAMDGHLD_02729 3e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PAMDGHLD_02730 0.0 fadF C COG0247 Fe-S oxidoreductase
PAMDGHLD_02731 8.3e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PAMDGHLD_02732 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PAMDGHLD_02733 6.4e-93 ywjG S Domain of unknown function (DUF2529)
PAMDGHLD_02734 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
PAMDGHLD_02735 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
PAMDGHLD_02736 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PAMDGHLD_02737 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PAMDGHLD_02738 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
PAMDGHLD_02739 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PAMDGHLD_02740 1.1e-32 rpmE J Binds the 23S rRNA
PAMDGHLD_02741 1.4e-104 tdk 2.7.1.21 F thymidine kinase
PAMDGHLD_02742 0.0 sfcA 1.1.1.38 C malic enzyme
PAMDGHLD_02743 3.6e-158 ywkB S Membrane transport protein
PAMDGHLD_02744 4.4e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
PAMDGHLD_02745 5.8e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAMDGHLD_02746 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PAMDGHLD_02747 6.1e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PAMDGHLD_02748 6.7e-60 ywlA S Uncharacterised protein family (UPF0715)
PAMDGHLD_02749 5.2e-119 spoIIR S stage II sporulation protein R
PAMDGHLD_02750 3.3e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
PAMDGHLD_02751 5.6e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PAMDGHLD_02752 4.5e-84 mntP P Probably functions as a manganese efflux pump
PAMDGHLD_02753 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAMDGHLD_02754 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
PAMDGHLD_02755 5.9e-97 ywlG S Belongs to the UPF0340 family
PAMDGHLD_02756 2.5e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PAMDGHLD_02757 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PAMDGHLD_02758 2.1e-61 atpI S ATP synthase
PAMDGHLD_02759 2.1e-129 atpB C it plays a direct role in the translocation of protons across the membrane
PAMDGHLD_02760 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PAMDGHLD_02761 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PAMDGHLD_02762 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PAMDGHLD_02763 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PAMDGHLD_02764 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PAMDGHLD_02765 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PAMDGHLD_02766 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PAMDGHLD_02767 2.3e-89 ywmA
PAMDGHLD_02768 1.3e-32 ywzB S membrane
PAMDGHLD_02769 7.4e-135 ywmB S TATA-box binding
PAMDGHLD_02770 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PAMDGHLD_02771 3.3e-189 spoIID D Stage II sporulation protein D
PAMDGHLD_02772 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
PAMDGHLD_02773 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
PAMDGHLD_02775 6.4e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PAMDGHLD_02776 1.6e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PAMDGHLD_02777 2.8e-93 S response regulator aspartate phosphatase
PAMDGHLD_02778 9.5e-83 ywmF S Peptidase M50
PAMDGHLD_02779 7.4e-10 csbD K CsbD-like
PAMDGHLD_02780 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PAMDGHLD_02781 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PAMDGHLD_02782 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PAMDGHLD_02783 4e-66 ywnA K Transcriptional regulator
PAMDGHLD_02785 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
PAMDGHLD_02786 9.7e-54 ywnC S Family of unknown function (DUF5362)
PAMDGHLD_02787 8.4e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAMDGHLD_02788 2.7e-68 ywnF S Family of unknown function (DUF5392)
PAMDGHLD_02789 1.2e-10 ywnC S Family of unknown function (DUF5362)
PAMDGHLD_02790 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
PAMDGHLD_02791 4.6e-120 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
PAMDGHLD_02792 5.1e-72 ywnJ S VanZ like family
PAMDGHLD_02793 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
PAMDGHLD_02794 1.9e-209 ftsW D Belongs to the SEDS family
PAMDGHLD_02795 1.7e-57 nrgB K Belongs to the P(II) protein family
PAMDGHLD_02796 2.5e-228 amt P Ammonium transporter
PAMDGHLD_02797 4.8e-102 phzA Q Isochorismatase family
PAMDGHLD_02798 2.7e-244 ywoD EGP Major facilitator superfamily
PAMDGHLD_02799 1.4e-275 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
PAMDGHLD_02800 4.9e-213 ywoG EGP Major facilitator Superfamily
PAMDGHLD_02801 8.5e-72 ywoH K transcriptional
PAMDGHLD_02802 1.8e-44 spoIIID K Stage III sporulation protein D
PAMDGHLD_02803 2.7e-180 mbl D Rod shape-determining protein
PAMDGHLD_02804 4e-118 flhO N flagellar basal body
PAMDGHLD_02805 4.4e-144 flhP N flagellar basal body
PAMDGHLD_02806 8.5e-201 S aspartate phosphatase
PAMDGHLD_02807 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PAMDGHLD_02808 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PAMDGHLD_02809 4.3e-68 ywpF S YwpF-like protein
PAMDGHLD_02810 4e-62 ywpG
PAMDGHLD_02811 3.7e-57 ssbB L Single-stranded DNA-binding protein
PAMDGHLD_02812 7.5e-138 glcR K DeoR C terminal sensor domain
PAMDGHLD_02813 1.1e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
PAMDGHLD_02814 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PAMDGHLD_02815 1.7e-306 ywqB S SWIM zinc finger
PAMDGHLD_02816 1.3e-14
PAMDGHLD_02817 5.7e-111 ywqC M biosynthesis protein
PAMDGHLD_02818 8.2e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
PAMDGHLD_02819 4.6e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
PAMDGHLD_02820 1.8e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PAMDGHLD_02821 3.9e-150 ywqG S Domain of unknown function (DUF1963)
PAMDGHLD_02823 7.9e-28 S Domain of unknown function (DUF5082)
PAMDGHLD_02824 7.3e-37 ywqI S Family of unknown function (DUF5344)
PAMDGHLD_02825 7.3e-258 ywqJ S Pre-toxin TG
PAMDGHLD_02826 8.8e-87
PAMDGHLD_02827 3.6e-50
PAMDGHLD_02829 2.7e-96
PAMDGHLD_02830 1.8e-133 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
PAMDGHLD_02831 2.8e-157 K Transcriptional regulator
PAMDGHLD_02832 1e-93 ywqN S NAD(P)H-dependent
PAMDGHLD_02834 3.8e-88 ywrA P COG2059 Chromate transport protein ChrA
PAMDGHLD_02835 3.9e-102 ywrB P Chromate transporter
PAMDGHLD_02836 1.1e-83 ywrC K Transcriptional regulator
PAMDGHLD_02837 1e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PAMDGHLD_02838 7.5e-18 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PAMDGHLD_02839 6.2e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PAMDGHLD_02840 1e-08
PAMDGHLD_02841 7.2e-211 cotH M Spore Coat
PAMDGHLD_02842 2.3e-130 cotB
PAMDGHLD_02843 4.4e-126 ywrJ
PAMDGHLD_02844 1.4e-240 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PAMDGHLD_02846 9e-167 alsR K LysR substrate binding domain
PAMDGHLD_02847 2.2e-307 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PAMDGHLD_02848 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
PAMDGHLD_02849 1.4e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
PAMDGHLD_02850 7.5e-89 batE T Sh3 type 3 domain protein
PAMDGHLD_02851 2.2e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
PAMDGHLD_02852 4.2e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
PAMDGHLD_02853 8.7e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PAMDGHLD_02854 2.1e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PAMDGHLD_02855 3e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAMDGHLD_02856 4.5e-180 rbsR K transcriptional
PAMDGHLD_02857 1.5e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
PAMDGHLD_02858 2.2e-191 gerKB E Spore germination protein
PAMDGHLD_02859 1e-183 gerKA EG Spore germination protein
PAMDGHLD_02861 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
PAMDGHLD_02862 2.3e-70 pgsC S biosynthesis protein
PAMDGHLD_02863 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
PAMDGHLD_02864 1.3e-20 ywtC
PAMDGHLD_02865 1.8e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PAMDGHLD_02866 7.7e-36 yttA 2.7.13.3 S Pfam Transposase IS66
PAMDGHLD_02867 5e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
PAMDGHLD_02868 1.9e-178 ywtF K Transcriptional regulator
PAMDGHLD_02869 3.2e-248 ywtG EGP Major facilitator Superfamily
PAMDGHLD_02870 1.4e-264 GT2,GT4 J Glycosyl transferase family 2
PAMDGHLD_02871 3.2e-214 gerAC S Spore germination protein
PAMDGHLD_02872 1.1e-195 gerBB E Spore germination protein
PAMDGHLD_02873 6.7e-265 gerBA EG Spore germination protein
PAMDGHLD_02874 6.3e-187 pmi 5.3.1.8 G mannose-6-phosphate isomerase
PAMDGHLD_02875 2.9e-242 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PAMDGHLD_02876 8.7e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PAMDGHLD_02877 7.7e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PAMDGHLD_02878 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
PAMDGHLD_02879 8.6e-279 M Glycosyltransferase like family 2
PAMDGHLD_02880 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PAMDGHLD_02881 2.8e-151 tagG GM Transport permease protein
PAMDGHLD_02882 7.1e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PAMDGHLD_02883 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PAMDGHLD_02884 2e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PAMDGHLD_02885 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PAMDGHLD_02886 1.3e-48
PAMDGHLD_02887 0.0 lytB 3.5.1.28 D Stage II sporulation protein
PAMDGHLD_02888 1e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PAMDGHLD_02889 1.4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PAMDGHLD_02890 2.3e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAMDGHLD_02891 4.1e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
PAMDGHLD_02892 1.5e-250 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PAMDGHLD_02893 1.4e-254 tuaE M Teichuronic acid biosynthesis protein
PAMDGHLD_02894 7.8e-115 tuaF M protein involved in exopolysaccharide biosynthesis
PAMDGHLD_02895 9.9e-143 tuaG GT2 M Glycosyltransferase like family 2
PAMDGHLD_02896 5.2e-239 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
PAMDGHLD_02897 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PAMDGHLD_02898 3.5e-171 yvhJ K Transcriptional regulator
PAMDGHLD_02899 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
PAMDGHLD_02900 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PAMDGHLD_02901 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAMDGHLD_02902 1.2e-157 degV S protein conserved in bacteria
PAMDGHLD_02903 1.7e-254 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PAMDGHLD_02904 1.7e-42 comFB S Late competence development protein ComFB
PAMDGHLD_02905 1.2e-77 comFC S Phosphoribosyl transferase domain
PAMDGHLD_02906 1.4e-74 yvyF S flagellar protein
PAMDGHLD_02907 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
PAMDGHLD_02908 7.6e-80 flgN NOU FlgN protein
PAMDGHLD_02909 6.3e-274 flgK N flagellar hook-associated protein
PAMDGHLD_02910 2.3e-162 flgL N Belongs to the bacterial flagellin family
PAMDGHLD_02911 1.4e-80 yviE
PAMDGHLD_02912 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PAMDGHLD_02913 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PAMDGHLD_02914 5.5e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PAMDGHLD_02915 1.6e-245 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PAMDGHLD_02916 3e-66 fliS N flagellar protein FliS
PAMDGHLD_02917 2.6e-10 fliT S bacterial-type flagellum organization
PAMDGHLD_02918 6.8e-68
PAMDGHLD_02919 1.4e-101 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PAMDGHLD_02920 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PAMDGHLD_02921 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PAMDGHLD_02922 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
PAMDGHLD_02923 2.4e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
PAMDGHLD_02924 1e-122 ftsE D cell division ATP-binding protein FtsE
PAMDGHLD_02925 9.2e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PAMDGHLD_02926 1.8e-227 ywoF P Right handed beta helix region
PAMDGHLD_02927 1.2e-255 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
PAMDGHLD_02928 1.5e-55 swrA S Swarming motility protein
PAMDGHLD_02929 1.8e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAMDGHLD_02930 2.7e-181 S Psort location CytoplasmicMembrane, score
PAMDGHLD_02932 1.1e-26 bacT Q Thioesterase domain
PAMDGHLD_02933 5.1e-227 yvkA EGP Major facilitator Superfamily
PAMDGHLD_02934 2.4e-110 yvkB K Transcriptional regulator
PAMDGHLD_02935 0.0 yvkC 2.7.9.2 GT Phosphotransferase
PAMDGHLD_02936 7.6e-33 csbA S protein conserved in bacteria
PAMDGHLD_02937 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PAMDGHLD_02938 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PAMDGHLD_02939 5e-32 yvkN
PAMDGHLD_02940 6.1e-49 yvlA
PAMDGHLD_02941 3.2e-166 yvlB S Putative adhesin
PAMDGHLD_02942 9.6e-26 pspB KT PspC domain
PAMDGHLD_02943 3.9e-41 yvlD S Membrane
PAMDGHLD_02944 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
PAMDGHLD_02945 6.2e-105 yxaF K Transcriptional regulator
PAMDGHLD_02946 2.3e-133 yvoA K transcriptional
PAMDGHLD_02947 5.7e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PAMDGHLD_02948 1.4e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PAMDGHLD_02949 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PAMDGHLD_02950 2.8e-151 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PAMDGHLD_02951 8.3e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PAMDGHLD_02952 3.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
PAMDGHLD_02953 3.1e-138 yvpB NU protein conserved in bacteria
PAMDGHLD_02954 1e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PAMDGHLD_02955 1.6e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PAMDGHLD_02956 1.9e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PAMDGHLD_02957 3e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PAMDGHLD_02958 3.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PAMDGHLD_02959 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PAMDGHLD_02960 6.8e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PAMDGHLD_02961 7.4e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
PAMDGHLD_02962 0.0 msbA2 3.6.3.44 V ABC transporter
PAMDGHLD_02963 1.2e-120 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_02964 1.6e-191 sasA T Histidine kinase
PAMDGHLD_02965 4.6e-274 S COG0457 FOG TPR repeat
PAMDGHLD_02966 2.5e-123 usp CBM50 M protein conserved in bacteria
PAMDGHLD_02967 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PAMDGHLD_02968 1.9e-86 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PAMDGHLD_02969 1.1e-166 rapZ S Displays ATPase and GTPase activities
PAMDGHLD_02970 3.8e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PAMDGHLD_02971 4.1e-170 whiA K May be required for sporulation
PAMDGHLD_02972 4.7e-36 crh G Phosphocarrier protein Chr
PAMDGHLD_02973 8.2e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
PAMDGHLD_02974 1.6e-79 M Ribonuclease
PAMDGHLD_02975 2.8e-182 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAMDGHLD_02976 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
PAMDGHLD_02977 9.5e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
PAMDGHLD_02978 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
PAMDGHLD_02979 3.4e-103 yvdD 3.2.2.10 S Belongs to the LOG family
PAMDGHLD_02980 1.3e-160 yvdE K Transcriptional regulator
PAMDGHLD_02981 4.9e-310 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
PAMDGHLD_02982 8.8e-205 mdxE G COG2182 Maltose-binding periplasmic proteins domains
PAMDGHLD_02983 4.1e-221 malC P COG1175 ABC-type sugar transport systems, permease components
PAMDGHLD_02984 8.6e-140 malD P transport
PAMDGHLD_02985 1.4e-108 malA S Protein of unknown function (DUF1189)
PAMDGHLD_02986 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
PAMDGHLD_02987 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
PAMDGHLD_02988 4.5e-94 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
PAMDGHLD_02989 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PAMDGHLD_02990 3.3e-183 scrR K transcriptional
PAMDGHLD_02991 4.7e-219 rafB P LacY proton/sugar symporter
PAMDGHLD_02992 2.6e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
PAMDGHLD_02994 3.4e-33
PAMDGHLD_02995 3e-265 I Pfam Lipase (class 3)
PAMDGHLD_02996 1e-16 S Protein of unknown function (DUF1433)
PAMDGHLD_02997 4.8e-43 I Pfam Lipase (class 3)
PAMDGHLD_02998 2.2e-38 S Protein of unknown function (DUF1433)
PAMDGHLD_02999 4.5e-16 S Protein of unknown function (DUF1433)
PAMDGHLD_03000 1.6e-93 padC Q Phenolic acid decarboxylase
PAMDGHLD_03001 9.2e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAMDGHLD_03002 4.8e-111 yyaS S Membrane
PAMDGHLD_03003 9.8e-97 ywjB H RibD C-terminal domain
PAMDGHLD_03004 4.6e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
PAMDGHLD_03005 5.7e-77 slr K transcriptional
PAMDGHLD_03006 8.4e-120 ywqC M biosynthesis protein
PAMDGHLD_03007 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
PAMDGHLD_03008 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
PAMDGHLD_03009 3.3e-219 epsD GT4 M Glycosyl transferase 4-like
PAMDGHLD_03010 2.3e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PAMDGHLD_03011 2.7e-213 epsF GT4 M Glycosyl transferases group 1
PAMDGHLD_03012 7.7e-205 epsG S EpsG family
PAMDGHLD_03013 6.4e-193 epsH GT2 S Glycosyltransferase like family 2
PAMDGHLD_03014 9.2e-203 epsI GM pyruvyl transferase
PAMDGHLD_03015 1.3e-193 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
PAMDGHLD_03016 4.5e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAMDGHLD_03017 1.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PAMDGHLD_03018 1.9e-54 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
PAMDGHLD_03019 6.3e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
PAMDGHLD_03020 3.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
PAMDGHLD_03021 2.7e-32 yvfG S YvfG protein
PAMDGHLD_03022 3.2e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PAMDGHLD_03023 2.2e-304 yvfH C L-lactate permease
PAMDGHLD_03024 6.6e-120 yvfI K COG2186 Transcriptional regulators
PAMDGHLD_03025 5.7e-222 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PAMDGHLD_03026 9.3e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PAMDGHLD_03027 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PAMDGHLD_03028 3.9e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PAMDGHLD_03031 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
PAMDGHLD_03032 2.1e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
PAMDGHLD_03033 1.3e-151 ybbH_1 K RpiR family transcriptional regulator
PAMDGHLD_03034 5.1e-167 3.1.3.104 S hydrolases of the HAD superfamily
PAMDGHLD_03035 1.4e-113 yyaS S Membrane
PAMDGHLD_03036 1.6e-182 purR7 5.1.1.1 K Transcriptional regulator
PAMDGHLD_03037 5e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
PAMDGHLD_03038 1.6e-158 yvbV EG EamA-like transporter family
PAMDGHLD_03039 9e-156 yvbU K Transcriptional regulator
PAMDGHLD_03041 1.9e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAMDGHLD_03042 4.2e-203 araR K transcriptional
PAMDGHLD_03043 3.7e-252 araE EGP Major facilitator Superfamily
PAMDGHLD_03045 8.9e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PAMDGHLD_03046 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PAMDGHLD_03047 1.5e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PAMDGHLD_03048 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PAMDGHLD_03049 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
PAMDGHLD_03050 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PAMDGHLD_03051 9.8e-236 ywaD 3.4.11.10, 3.4.11.6 S PA domain
PAMDGHLD_03052 2e-255 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PAMDGHLD_03053 4e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
PAMDGHLD_03054 2.6e-169 5.1.3.2 M GDP-mannose 4,6 dehydratase
PAMDGHLD_03055 1.2e-230 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PAMDGHLD_03056 9.2e-148 M Protein involved in cellulose biosynthesis
PAMDGHLD_03057 2.5e-143 C WbqC-like protein family
PAMDGHLD_03058 1.2e-126 S GlcNAc-PI de-N-acetylase
PAMDGHLD_03059 3.2e-180
PAMDGHLD_03060 9.5e-212 EGP Major facilitator Superfamily
PAMDGHLD_03061 2.5e-80 yvbK 3.1.3.25 K acetyltransferase
PAMDGHLD_03062 0.0 tcaA S response to antibiotic
PAMDGHLD_03063 7.1e-119 exoY M Membrane
PAMDGHLD_03064 5.2e-105 yvbG U UPF0056 membrane protein
PAMDGHLD_03065 7.9e-97 yvbF K Belongs to the GbsR family
PAMDGHLD_03066 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PAMDGHLD_03067 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
PAMDGHLD_03068 7.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PAMDGHLD_03069 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
PAMDGHLD_03070 4.3e-76 yvbF K Belongs to the GbsR family
PAMDGHLD_03071 1.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PAMDGHLD_03072 1.2e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
PAMDGHLD_03073 3.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PAMDGHLD_03074 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
PAMDGHLD_03075 1e-125 mutF V ABC transporter, ATP-binding protein
PAMDGHLD_03076 2.7e-121 spaE S ABC-2 family transporter protein
PAMDGHLD_03077 1.5e-135 mutG S ABC-2 family transporter protein
PAMDGHLD_03078 5.8e-123 K Transcriptional regulatory protein, C terminal
PAMDGHLD_03079 3.2e-256 T His Kinase A (phosphoacceptor) domain
PAMDGHLD_03080 4.4e-52 yodB K transcriptional
PAMDGHLD_03081 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
PAMDGHLD_03082 1e-69 K transcriptional
PAMDGHLD_03083 6e-35 yvzC K Transcriptional
PAMDGHLD_03084 4.8e-24 secG U Preprotein translocase subunit SecG
PAMDGHLD_03085 7.4e-143 est 3.1.1.1 S Carboxylesterase
PAMDGHLD_03086 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PAMDGHLD_03087 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PAMDGHLD_03089 2.5e-32 S Phage integrase family
PAMDGHLD_03092 2.8e-13 S AAA ATPase domain
PAMDGHLD_03094 2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PAMDGHLD_03095 1e-159 ytlI K LysR substrate binding domain
PAMDGHLD_03096 3.3e-100 ytmI K Acetyltransferase (GNAT) domain
PAMDGHLD_03097 3e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
PAMDGHLD_03098 1e-145 tcyK M Bacterial periplasmic substrate-binding proteins
PAMDGHLD_03099 2e-121 tcyL P Binding-protein-dependent transport system inner membrane component
PAMDGHLD_03100 1.1e-119 tcyM U Binding-protein-dependent transport system inner membrane component
PAMDGHLD_03101 8e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PAMDGHLD_03102 7.1e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAMDGHLD_03103 6.6e-47 ytnI O COG0695 Glutaredoxin and related proteins
PAMDGHLD_03104 5.4e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PAMDGHLD_03105 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PAMDGHLD_03106 8.4e-193 yvaA 1.1.1.371 S Oxidoreductase
PAMDGHLD_03107 3.7e-48 csoR S transcriptional
PAMDGHLD_03108 9.9e-29 copZ P Heavy-metal-associated domain
PAMDGHLD_03109 0.0 copA 3.6.3.54 P P-type ATPase
PAMDGHLD_03110 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PAMDGHLD_03111 3.1e-100 bdbD O Thioredoxin
PAMDGHLD_03112 1e-72 bdbC O Required for disulfide bond formation in some proteins
PAMDGHLD_03113 1.3e-140 S Metallo-peptidase family M12
PAMDGHLD_03114 3.5e-106 yvgT S membrane
PAMDGHLD_03115 0.0 helD 3.6.4.12 L DNA helicase
PAMDGHLD_03116 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PAMDGHLD_03117 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PAMDGHLD_03118 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
PAMDGHLD_03119 2.7e-85 yvgO
PAMDGHLD_03120 1.5e-155 yvgN S reductase
PAMDGHLD_03121 2.2e-194 yfiN V COG0842 ABC-type multidrug transport system, permease component
PAMDGHLD_03122 4.7e-194 yfiM V ABC-2 type transporter
PAMDGHLD_03123 4.7e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
PAMDGHLD_03124 1.8e-177 T Histidine kinase
PAMDGHLD_03125 1.3e-114 yfiK K Regulator
PAMDGHLD_03126 1e-98 modB P COG4149 ABC-type molybdate transport system, permease component
PAMDGHLD_03127 4.1e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
PAMDGHLD_03128 1.5e-164 yvgK P COG1910 Periplasmic molybdate-binding protein domain
PAMDGHLD_03129 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PAMDGHLD_03130 3.9e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
PAMDGHLD_03131 3.6e-14 S Small spore protein J (Spore_SspJ)
PAMDGHLD_03132 1.3e-236 yvsH E Arginine ornithine antiporter
PAMDGHLD_03133 4.4e-177 fhuD P ABC transporter
PAMDGHLD_03134 6.6e-185 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAMDGHLD_03135 2.6e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAMDGHLD_03136 1.8e-147 fhuC 3.6.3.34 HP ABC transporter
PAMDGHLD_03137 2.9e-67 yvrL S Regulatory protein YrvL
PAMDGHLD_03138 2.1e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
PAMDGHLD_03139 1.2e-15 S YvrJ protein family
PAMDGHLD_03140 9.9e-103 yvrI K RNA polymerase
PAMDGHLD_03141 1.1e-36
PAMDGHLD_03142 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_03143 0.0 T PhoQ Sensor
PAMDGHLD_03144 2.2e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
PAMDGHLD_03145 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PAMDGHLD_03146 5.5e-167 yvrC P ABC transporter substrate-binding protein
PAMDGHLD_03147 1e-177 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAMDGHLD_03148 1.1e-220 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
PAMDGHLD_03149 9.2e-101 yvqK 2.5.1.17 S Adenosyltransferase
PAMDGHLD_03150 4.8e-227 yvqJ EGP Major facilitator Superfamily
PAMDGHLD_03151 1.6e-45 liaI S membrane
PAMDGHLD_03152 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
PAMDGHLD_03153 8.7e-143 liaG S Putative adhesin
PAMDGHLD_03154 9.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
PAMDGHLD_03155 2.3e-193 vraS 2.7.13.3 T Histidine kinase
PAMDGHLD_03156 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAMDGHLD_03157 8.6e-204 gerAC S Spore germination B3/ GerAC like, C-terminal
PAMDGHLD_03158 1.1e-187 gerAB E Spore germination protein
PAMDGHLD_03159 7.9e-258 gerAA EG Spore germination protein
PAMDGHLD_03160 6.6e-24 S Protein of unknown function (DUF3970)
PAMDGHLD_03161 1.1e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PAMDGHLD_03162 1e-157 yuxN K Transcriptional regulator
PAMDGHLD_03163 1.3e-23
PAMDGHLD_03164 1e-251 cssS 2.7.13.3 T PhoQ Sensor
PAMDGHLD_03165 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_03166 8.5e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PAMDGHLD_03167 8e-79 dps P Belongs to the Dps family
PAMDGHLD_03168 3.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PAMDGHLD_03169 0.0 pepF2 E COG1164 Oligoendopeptidase F
PAMDGHLD_03170 1.2e-44 S YusW-like protein
PAMDGHLD_03171 1.4e-150 yusV 3.6.3.34 HP ABC transporter
PAMDGHLD_03172 3.3e-39 yusU S Protein of unknown function (DUF2573)
PAMDGHLD_03173 4.7e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAMDGHLD_03174 5.5e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
PAMDGHLD_03175 3.1e-156 ywbI2 K Transcriptional regulator
PAMDGHLD_03176 1.4e-156 yusT K LysR substrate binding domain
PAMDGHLD_03177 6.9e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PAMDGHLD_03178 6.4e-66 yusQ S Tautomerase enzyme
PAMDGHLD_03179 8.1e-288 yusP P Major facilitator superfamily
PAMDGHLD_03180 8.3e-68 yusO K Iron dependent repressor, N-terminal DNA binding domain
PAMDGHLD_03181 7.1e-53 yusN M Coat F domain
PAMDGHLD_03182 3.9e-43
PAMDGHLD_03183 1.9e-164 fadM E Proline dehydrogenase
PAMDGHLD_03184 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
PAMDGHLD_03185 9.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
PAMDGHLD_03186 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
PAMDGHLD_03187 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
PAMDGHLD_03188 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PAMDGHLD_03189 1.4e-39 yusG S Protein of unknown function (DUF2553)
PAMDGHLD_03190 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
PAMDGHLD_03191 1.6e-54 yusE CO Thioredoxin
PAMDGHLD_03192 5e-57 yusD S SCP-2 sterol transfer family
PAMDGHLD_03193 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PAMDGHLD_03194 8.3e-93 metI P COG2011 ABC-type metal ion transport system, permease component
PAMDGHLD_03195 5.1e-145 metQ P Belongs to the NlpA lipoprotein family
PAMDGHLD_03196 2.2e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PAMDGHLD_03197 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PAMDGHLD_03198 7e-245 sufD O assembly protein SufD
PAMDGHLD_03199 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PAMDGHLD_03200 3.2e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
PAMDGHLD_03201 3e-270 sufB O FeS cluster assembly
PAMDGHLD_03202 1.5e-155 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
PAMDGHLD_03203 4.2e-80 yncE S Protein of unknown function (DUF2691)
PAMDGHLD_03204 4.7e-24
PAMDGHLD_03205 5.6e-34
PAMDGHLD_03206 1.7e-204 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
PAMDGHLD_03207 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
PAMDGHLD_03209 7.1e-23 S Sporulation delaying protein SdpA
PAMDGHLD_03210 1.7e-75
PAMDGHLD_03211 4e-14
PAMDGHLD_03212 2.9e-165 K helix_turn_helix, mercury resistance
PAMDGHLD_03213 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PAMDGHLD_03214 4e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
PAMDGHLD_03215 2.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
PAMDGHLD_03216 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
PAMDGHLD_03217 3.1e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
PAMDGHLD_03218 1e-133 yurK K UTRA
PAMDGHLD_03219 2.4e-206 msmX P Belongs to the ABC transporter superfamily
PAMDGHLD_03220 1.2e-168 bsn L Ribonuclease
PAMDGHLD_03221 2.2e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PAMDGHLD_03222 6.2e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PAMDGHLD_03223 3.8e-213 blt EGP Major facilitator Superfamily
PAMDGHLD_03224 1.3e-26
PAMDGHLD_03225 5.1e-08
PAMDGHLD_03227 4.7e-14 yqbD 2.1.1.72 L Putative phage serine protease XkdF
PAMDGHLD_03228 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
PAMDGHLD_03229 6.5e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
PAMDGHLD_03230 9.8e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
PAMDGHLD_03231 8.1e-170 yunF S Protein of unknown function DUF72
PAMDGHLD_03232 5.1e-145 yunE S membrane transporter protein
PAMDGHLD_03233 4.5e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PAMDGHLD_03234 2.5e-130 yunB S Sporulation protein YunB (Spo_YunB)
PAMDGHLD_03235 3.8e-195 lytH M Peptidase, M23
PAMDGHLD_03236 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PAMDGHLD_03237 1.7e-47 yutD S protein conserved in bacteria
PAMDGHLD_03238 9.5e-74 yutE S Protein of unknown function DUF86
PAMDGHLD_03239 5.1e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PAMDGHLD_03240 7.3e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
PAMDGHLD_03241 3.2e-197 yutH S Spore coat protein
PAMDGHLD_03242 3.5e-241 hom 1.1.1.3 E homoserine dehydrogenase
PAMDGHLD_03243 1.1e-195 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PAMDGHLD_03244 1.2e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PAMDGHLD_03245 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
PAMDGHLD_03246 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
PAMDGHLD_03247 9.7e-55 yuzD S protein conserved in bacteria
PAMDGHLD_03248 4.7e-207 yutJ 1.6.99.3 C NADH dehydrogenase
PAMDGHLD_03249 2.4e-39 yuzB S Belongs to the UPF0349 family
PAMDGHLD_03250 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PAMDGHLD_03251 1.6e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PAMDGHLD_03252 7e-62 erpA S Belongs to the HesB IscA family
PAMDGHLD_03253 2.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
PAMDGHLD_03254 1.8e-93 rimJ 2.3.1.128 J Alanine acetyltransferase
PAMDGHLD_03256 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
PAMDGHLD_03258 1.8e-122 V ABC transporter
PAMDGHLD_03259 3.1e-71 CP Membrane
PAMDGHLD_03260 1.8e-28
PAMDGHLD_03261 3.5e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PAMDGHLD_03263 1.5e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
PAMDGHLD_03264 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
PAMDGHLD_03265 3.8e-27 yuiB S Putative membrane protein
PAMDGHLD_03266 3.5e-117 yuiC S protein conserved in bacteria
PAMDGHLD_03267 1.3e-76 yuiD S protein conserved in bacteria
PAMDGHLD_03268 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PAMDGHLD_03269 1.1e-208 yuiF S antiporter
PAMDGHLD_03270 1.1e-101 bioY S Biotin biosynthesis protein
PAMDGHLD_03271 1.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
PAMDGHLD_03272 2.3e-164 besA S Putative esterase
PAMDGHLD_03273 2.5e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PAMDGHLD_03274 1.8e-223 entC 5.4.4.2 HQ Isochorismate synthase
PAMDGHLD_03275 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
PAMDGHLD_03276 5.5e-172 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
PAMDGHLD_03277 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAMDGHLD_03278 5.3e-33 mbtH S MbtH-like protein
PAMDGHLD_03279 7.5e-134 yukJ S Uncharacterized conserved protein (DUF2278)
PAMDGHLD_03280 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
PAMDGHLD_03281 9.5e-228 yukF QT Transcriptional regulator
PAMDGHLD_03282 2.8e-45 esxA S Belongs to the WXG100 family
PAMDGHLD_03283 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
PAMDGHLD_03284 2.4e-205 essB S WXG100 protein secretion system (Wss), protein YukC
PAMDGHLD_03285 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PAMDGHLD_03286 0.0 esaA S type VII secretion protein EsaA
PAMDGHLD_03287 6.9e-78 yueC S Family of unknown function (DUF5383)
PAMDGHLD_03288 6.4e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAMDGHLD_03289 3.7e-96 yueE S phosphohydrolase
PAMDGHLD_03290 2.1e-22 S Protein of unknown function (DUF2642)
PAMDGHLD_03291 5.6e-187 yueF S transporter activity
PAMDGHLD_03292 6.4e-34 yueG S Spore germination protein gerPA/gerPF
PAMDGHLD_03293 2.8e-38 yueH S YueH-like protein
PAMDGHLD_03294 7.2e-68 yueI S Protein of unknown function (DUF1694)
PAMDGHLD_03295 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
PAMDGHLD_03296 2.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PAMDGHLD_03297 3.5e-230 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
PAMDGHLD_03298 3.1e-51 yuzC
PAMDGHLD_03301 8.6e-148 comQ H Polyprenyl synthetase
PAMDGHLD_03303 0.0 comP 2.7.13.3 T Histidine kinase
PAMDGHLD_03304 2.1e-45 comP 2.7.13.3 T Histidine kinase
PAMDGHLD_03305 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PAMDGHLD_03306 3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
PAMDGHLD_03307 1.1e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
PAMDGHLD_03308 1.5e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PAMDGHLD_03309 9.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PAMDGHLD_03310 1.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PAMDGHLD_03311 1.2e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PAMDGHLD_03312 9.2e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PAMDGHLD_03313 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PAMDGHLD_03314 1.2e-13
PAMDGHLD_03315 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
PAMDGHLD_03316 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
PAMDGHLD_03317 2.8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PAMDGHLD_03318 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
PAMDGHLD_03319 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
PAMDGHLD_03320 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PAMDGHLD_03321 3.6e-73 yufK S Family of unknown function (DUF5366)
PAMDGHLD_03322 3.8e-72 yuxK S protein conserved in bacteria
PAMDGHLD_03323 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
PAMDGHLD_03324 1.8e-178 yuxJ EGP Major facilitator Superfamily
PAMDGHLD_03325 4.5e-118 kapD L the KinA pathway to sporulation
PAMDGHLD_03326 2e-67 kapB G Kinase associated protein B
PAMDGHLD_03327 2.2e-227 T PhoQ Sensor
PAMDGHLD_03328 7.1e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PAMDGHLD_03329 1.4e-40 yugE S Domain of unknown function (DUF1871)
PAMDGHLD_03330 3.2e-155 yugF I Hydrolase
PAMDGHLD_03331 2e-83 alaR K Transcriptional regulator
PAMDGHLD_03332 5.5e-209 yugH 2.6.1.1 E Aminotransferase
PAMDGHLD_03333 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
PAMDGHLD_03334 1.8e-34 yuzA S Domain of unknown function (DUF378)
PAMDGHLD_03335 3.2e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
PAMDGHLD_03336 7.4e-230 yugK C Dehydrogenase
PAMDGHLD_03337 1.4e-118 ycaC Q Isochorismatase family
PAMDGHLD_03338 1.5e-95 S NADPH-dependent FMN reductase
PAMDGHLD_03339 1.9e-258 pgi 5.3.1.9 G Belongs to the GPI family
PAMDGHLD_03341 2.8e-72 yugN S YugN-like family
PAMDGHLD_03342 1.8e-181 yugO P COG1226 Kef-type K transport systems
PAMDGHLD_03343 1.1e-26 mstX S Membrane-integrating protein Mistic
PAMDGHLD_03344 3.4e-18
PAMDGHLD_03345 8.3e-117 yugP S Zn-dependent protease
PAMDGHLD_03346 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
PAMDGHLD_03347 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
PAMDGHLD_03348 4.8e-75 yugU S Uncharacterised protein family UPF0047
PAMDGHLD_03349 1.9e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PAMDGHLD_03350 1.1e-40
PAMDGHLD_03351 1.3e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
PAMDGHLD_03352 1.1e-220 mcpA NT chemotaxis protein
PAMDGHLD_03353 7.6e-235 mcpA NT chemotaxis protein
PAMDGHLD_03354 6.6e-223 mcpA NT chemotaxis protein
PAMDGHLD_03355 1.1e-233 mcpA NT chemotaxis protein
PAMDGHLD_03356 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
PAMDGHLD_03357 8.8e-184 ygjR S Oxidoreductase
PAMDGHLD_03358 7.6e-195 yubA S transporter activity
PAMDGHLD_03359 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PAMDGHLD_03361 1.9e-50 yjcN
PAMDGHLD_03362 3.1e-121 G Cupin
PAMDGHLD_03363 1.5e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PAMDGHLD_03364 1.1e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PAMDGHLD_03365 2.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
PAMDGHLD_03366 3.9e-93 yuaB
PAMDGHLD_03367 6e-97 yuaC K Belongs to the GbsR family
PAMDGHLD_03368 1.1e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
PAMDGHLD_03369 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
PAMDGHLD_03370 2.5e-109 yuaD S MOSC domain
PAMDGHLD_03371 1.2e-80 yuaE S DinB superfamily
PAMDGHLD_03372 4.3e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
PAMDGHLD_03373 7.7e-179 yuaG 3.4.21.72 S protein conserved in bacteria
PAMDGHLD_03374 2e-95 thiT S Thiamine transporter protein (Thia_YuaJ)
PAMDGHLD_03376 3.4e-39 S COG NOG14552 non supervised orthologous group
PAMDGHLD_03381 1.6e-08
PAMDGHLD_03388 1.3e-09
PAMDGHLD_03389 7.8e-08
PAMDGHLD_03398 1.5e-77 tspO T membrane
PAMDGHLD_03399 1.7e-131 dksA T COG1734 DnaK suppressor protein
PAMDGHLD_03400 2e-269 menF 5.4.4.2 HQ Isochorismate synthase
PAMDGHLD_03401 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PAMDGHLD_03402 2.5e-155 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PAMDGHLD_03403 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PAMDGHLD_03404 7e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PAMDGHLD_03405 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PAMDGHLD_03406 2.3e-24 S Domain of Unknown Function (DUF1540)
PAMDGHLD_03407 2.2e-185 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
PAMDGHLD_03408 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
PAMDGHLD_03409 1.6e-41 rpmE2 J Ribosomal protein L31
PAMDGHLD_03410 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
PAMDGHLD_03411 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PAMDGHLD_03412 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PAMDGHLD_03413 1.6e-76 ytkA S YtkA-like
PAMDGHLD_03415 1.6e-76 dps P Belongs to the Dps family
PAMDGHLD_03416 1.7e-61 ytkC S Bacteriophage holin family
PAMDGHLD_03417 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
PAMDGHLD_03418 4.6e-122 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PAMDGHLD_03419 1.7e-142 ytlC P ABC transporter
PAMDGHLD_03420 4.7e-185 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PAMDGHLD_03421 2.6e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PAMDGHLD_03422 1.6e-38 ytmB S Protein of unknown function (DUF2584)
PAMDGHLD_03423 6.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PAMDGHLD_03424 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PAMDGHLD_03425 0.0 asnB 6.3.5.4 E Asparagine synthase
PAMDGHLD_03426 1.3e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
PAMDGHLD_03427 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PAMDGHLD_03428 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
PAMDGHLD_03429 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
PAMDGHLD_03430 2.8e-143 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
PAMDGHLD_03432 1.9e-106 ytqB J Putative rRNA methylase
PAMDGHLD_03433 2.1e-190 yhcC S Fe-S oxidoreductase
PAMDGHLD_03434 2.8e-39 ytzC S Protein of unknown function (DUF2524)
PAMDGHLD_03436 3.9e-66 ytrA K GntR family transcriptional regulator
PAMDGHLD_03437 3.8e-162 ytrB P abc transporter atp-binding protein
PAMDGHLD_03438 1.2e-161 S ABC-2 family transporter protein
PAMDGHLD_03439 1.6e-161 P ABC-2 family transporter protein
PAMDGHLD_03440 6.5e-147
PAMDGHLD_03441 1.3e-125 ytrE V ABC transporter, ATP-binding protein
PAMDGHLD_03442 3.7e-222 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
PAMDGHLD_03443 5.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_03444 1.2e-169 T PhoQ Sensor
PAMDGHLD_03445 9.8e-135 bceA V ABC transporter, ATP-binding protein
PAMDGHLD_03446 0.0 bceB V ABC transporter (permease)
PAMDGHLD_03447 2.7e-126 ywaF S Integral membrane protein
PAMDGHLD_03448 1.8e-207 yttB EGP Major facilitator Superfamily
PAMDGHLD_03449 5.8e-138 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
PAMDGHLD_03450 1.2e-52 ytvB S Protein of unknown function (DUF4257)
PAMDGHLD_03451 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PAMDGHLD_03452 4.8e-51 ytwF P Sulfurtransferase
PAMDGHLD_03453 6e-85 M Acetyltransferase (GNAT) domain
PAMDGHLD_03454 1.1e-250 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
PAMDGHLD_03455 1.4e-142 amyC P ABC transporter (permease)
PAMDGHLD_03456 1.1e-164 amyD G Binding-protein-dependent transport system inner membrane component
PAMDGHLD_03457 1.5e-244 msmE G Bacterial extracellular solute-binding protein
PAMDGHLD_03458 7.5e-186 msmR K Transcriptional regulator
PAMDGHLD_03459 9e-26 yteV S Sporulation protein Cse60
PAMDGHLD_03460 5.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
PAMDGHLD_03461 3.3e-236 ytfP S HI0933-like protein
PAMDGHLD_03462 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAMDGHLD_03463 8.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PAMDGHLD_03464 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
PAMDGHLD_03465 5.4e-127 ythP V ABC transporter
PAMDGHLD_03466 3.5e-216 ythQ U Bacterial ABC transporter protein EcsB
PAMDGHLD_03467 4.1e-229 pbuO S permease
PAMDGHLD_03468 1.6e-268 pepV 3.5.1.18 E Dipeptidase
PAMDGHLD_03469 3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PAMDGHLD_03470 1.4e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PAMDGHLD_03471 2e-169 ytlQ
PAMDGHLD_03472 5.7e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PAMDGHLD_03473 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
PAMDGHLD_03474 4.6e-45 ytzH S YtzH-like protein
PAMDGHLD_03475 1.2e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PAMDGHLD_03476 4.3e-163 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
PAMDGHLD_03477 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
PAMDGHLD_03478 1.7e-51 ytzB S small secreted protein
PAMDGHLD_03479 3.7e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PAMDGHLD_03480 2.5e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
PAMDGHLD_03481 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PAMDGHLD_03482 4.9e-148 ytpQ S Belongs to the UPF0354 family
PAMDGHLD_03483 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PAMDGHLD_03484 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
PAMDGHLD_03485 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PAMDGHLD_03486 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PAMDGHLD_03487 1.7e-16 ytxH S COG4980 Gas vesicle protein
PAMDGHLD_03488 2.9e-43 ytxJ O Protein of unknown function (DUF2847)
PAMDGHLD_03489 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PAMDGHLD_03490 4.2e-181 ccpA K catabolite control protein A
PAMDGHLD_03491 5.1e-145 motA N flagellar motor
PAMDGHLD_03492 1.5e-118 motS N Flagellar motor protein
PAMDGHLD_03493 3.6e-229 acuC BQ histone deacetylase
PAMDGHLD_03494 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
PAMDGHLD_03495 8.9e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PAMDGHLD_03496 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PAMDGHLD_03497 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PAMDGHLD_03498 1.9e-47 azlD S Branched-chain amino acid transport protein (AzlD)
PAMDGHLD_03499 3.4e-124 azlC E AzlC protein
PAMDGHLD_03500 3.7e-148 K Transcriptional regulator
PAMDGHLD_03501 5.6e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAMDGHLD_03502 1.9e-138 E GDSL-like Lipase/Acylhydrolase family
PAMDGHLD_03504 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
PAMDGHLD_03505 2.5e-09
PAMDGHLD_03506 1.2e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PAMDGHLD_03507 1.4e-16
PAMDGHLD_03509 1.5e-13 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PAMDGHLD_03510 2.3e-45 S HicB_like antitoxin of bacterial toxin-antitoxin system
PAMDGHLD_03512 1.3e-102 yokH G SMI1 / KNR4 family
PAMDGHLD_03513 2.9e-254 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
PAMDGHLD_03514 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PAMDGHLD_03515 7.3e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
PAMDGHLD_03516 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
PAMDGHLD_03517 6.5e-108 yttP K Transcriptional regulator
PAMDGHLD_03518 7.3e-152 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
PAMDGHLD_03519 1.1e-261 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PAMDGHLD_03520 6.9e-240 braB E Component of the transport system for branched-chain amino acids
PAMDGHLD_03521 3.5e-208 iscS2 2.8.1.7 E Cysteine desulfurase
PAMDGHLD_03522 6.6e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PAMDGHLD_03523 3.9e-31 sspB S spore protein
PAMDGHLD_03524 1.6e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PAMDGHLD_03525 0.0 ytcJ S amidohydrolase
PAMDGHLD_03526 3.3e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PAMDGHLD_03527 6.4e-182 sppA OU signal peptide peptidase SppA
PAMDGHLD_03528 4.5e-88 yteJ S RDD family
PAMDGHLD_03529 1.6e-107 ytfI S Protein of unknown function (DUF2953)
PAMDGHLD_03530 1.6e-60 ytfJ S Sporulation protein YtfJ
PAMDGHLD_03531 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PAMDGHLD_03532 2.4e-181 ytxK 2.1.1.72 L DNA methylase
PAMDGHLD_03533 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PAMDGHLD_03534 4.7e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PAMDGHLD_03535 9.6e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PAMDGHLD_03536 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
PAMDGHLD_03538 1e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAMDGHLD_03539 1.1e-129 ytkL S Belongs to the UPF0173 family
PAMDGHLD_03540 6.3e-238 ytoI K transcriptional regulator containing CBS domains
PAMDGHLD_03541 1.5e-46 ytpI S YtpI-like protein
PAMDGHLD_03542 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
PAMDGHLD_03543 4.4e-23
PAMDGHLD_03544 5.1e-87 ytrI
PAMDGHLD_03545 3.2e-56 ytrH S Sporulation protein YtrH
PAMDGHLD_03546 0.0 dnaE 2.7.7.7 L DNA polymerase
PAMDGHLD_03547 7.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
PAMDGHLD_03548 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PAMDGHLD_03549 1.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PAMDGHLD_03550 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PAMDGHLD_03551 6.4e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PAMDGHLD_03552 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
PAMDGHLD_03553 8.1e-194 ytvI S sporulation integral membrane protein YtvI
PAMDGHLD_03554 1.1e-72 yeaL S membrane
PAMDGHLD_03555 2.9e-48 yjdF S Protein of unknown function (DUF2992)
PAMDGHLD_03556 7.1e-53
PAMDGHLD_03557 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
PAMDGHLD_03558 1.2e-241 icd 1.1.1.42 C isocitrate
PAMDGHLD_03559 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
PAMDGHLD_03560 8.5e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PAMDGHLD_03561 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
PAMDGHLD_03562 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PAMDGHLD_03563 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PAMDGHLD_03564 1.6e-106 ytaF P Probably functions as a manganese efflux pump
PAMDGHLD_03565 5.2e-99 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PAMDGHLD_03566 7.6e-160 ytbE S reductase
PAMDGHLD_03567 2.9e-205 ytbD EGP Major facilitator Superfamily
PAMDGHLD_03568 2e-67 ytcD K Transcriptional regulator
PAMDGHLD_03569 4.4e-194 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PAMDGHLD_03570 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PAMDGHLD_03571 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PAMDGHLD_03572 7.2e-248 dnaB L Membrane attachment protein
PAMDGHLD_03573 5.6e-172 dnaI L Primosomal protein DnaI
PAMDGHLD_03574 7.4e-107 ytxB S SNARE associated Golgi protein
PAMDGHLD_03575 8e-154 ytxC S YtxC-like family
PAMDGHLD_03576 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PAMDGHLD_03577 1e-150 ysaA S HAD-hyrolase-like
PAMDGHLD_03578 0.0 lytS 2.7.13.3 T Histidine kinase
PAMDGHLD_03579 2.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
PAMDGHLD_03580 9.1e-40 lrgA S effector of murein hydrolase LrgA
PAMDGHLD_03581 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PAMDGHLD_03582 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PAMDGHLD_03583 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PAMDGHLD_03584 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PAMDGHLD_03585 7e-43 ysdA S Membrane
PAMDGHLD_03586 1.7e-66 ysdB S Sigma-w pathway protein YsdB
PAMDGHLD_03587 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
PAMDGHLD_03588 6.4e-187 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
PAMDGHLD_03589 9.9e-296 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PAMDGHLD_03590 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
PAMDGHLD_03591 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PAMDGHLD_03592 7.5e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
PAMDGHLD_03593 8.8e-223 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PAMDGHLD_03594 4.4e-252 araN G carbohydrate transport
PAMDGHLD_03595 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
PAMDGHLD_03596 1.2e-144 araQ G transport system permease
PAMDGHLD_03597 1.2e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
PAMDGHLD_03598 0.0 cstA T Carbon starvation protein
PAMDGHLD_03599 8.9e-256 glcF C Glycolate oxidase
PAMDGHLD_03600 4.1e-259 glcD 1.1.3.15 C FAD binding domain
PAMDGHLD_03601 3.8e-204 ysfB KT regulator
PAMDGHLD_03602 2e-32 sspI S Belongs to the SspI family
PAMDGHLD_03603 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PAMDGHLD_03604 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PAMDGHLD_03605 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PAMDGHLD_03606 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PAMDGHLD_03607 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PAMDGHLD_03608 1.6e-83 cvpA S membrane protein, required for colicin V production
PAMDGHLD_03609 0.0 polX L COG1796 DNA polymerase IV (family X)
PAMDGHLD_03610 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PAMDGHLD_03611 4.7e-67 yshE S membrane
PAMDGHLD_03612 7.8e-73 ywbB S Protein of unknown function (DUF2711)
PAMDGHLD_03613 5.9e-38 ywbB S Protein of unknown function (DUF2711)
PAMDGHLD_03614 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PAMDGHLD_03615 9.2e-104 fadR K Transcriptional regulator
PAMDGHLD_03616 7e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
PAMDGHLD_03617 2.8e-137 etfB C Electron transfer flavoprotein
PAMDGHLD_03618 2.5e-178 etfA C Electron transfer flavoprotein
PAMDGHLD_03619 4.3e-299 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
PAMDGHLD_03620 2.5e-52 trxA O Belongs to the thioredoxin family
PAMDGHLD_03621 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PAMDGHLD_03622 2.4e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
PAMDGHLD_03623 1.2e-79 yslB S Protein of unknown function (DUF2507)
PAMDGHLD_03624 4.8e-108 sdhC C succinate dehydrogenase
PAMDGHLD_03625 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
PAMDGHLD_03626 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
PAMDGHLD_03627 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
PAMDGHLD_03628 2e-30 gerE K Transcriptional regulator
PAMDGHLD_03629 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
PAMDGHLD_03630 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PAMDGHLD_03631 6.9e-198 gerM S COG5401 Spore germination protein
PAMDGHLD_03632 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PAMDGHLD_03633 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PAMDGHLD_03634 4.5e-91 ysnB S Phosphoesterase
PAMDGHLD_03639 0.0 ilvB 2.2.1.6 E Acetolactate synthase
PAMDGHLD_03640 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
PAMDGHLD_03641 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PAMDGHLD_03642 1.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PAMDGHLD_03643 3.1e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PAMDGHLD_03644 2.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PAMDGHLD_03645 1.8e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PAMDGHLD_03646 4.1e-189 ysoA H Tetratricopeptide repeat
PAMDGHLD_03647 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PAMDGHLD_03648 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PAMDGHLD_03649 1.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
PAMDGHLD_03650 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PAMDGHLD_03651 3.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
PAMDGHLD_03652 1.1e-86 ysxD
PAMDGHLD_03653 4.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PAMDGHLD_03654 3.6e-146 hemX O cytochrome C
PAMDGHLD_03655 2.1e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PAMDGHLD_03656 9.5e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PAMDGHLD_03657 1.7e-184 hemB 4.2.1.24 H Belongs to the ALAD family
PAMDGHLD_03658 1.1e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
PAMDGHLD_03659 1.3e-223 spoVID M stage VI sporulation protein D
PAMDGHLD_03660 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PAMDGHLD_03661 6.1e-25
PAMDGHLD_03662 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PAMDGHLD_03663 3e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PAMDGHLD_03664 3.5e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PAMDGHLD_03665 3.1e-136 spoIIB S Sporulation related domain
PAMDGHLD_03666 3.5e-100 maf D septum formation protein Maf
PAMDGHLD_03667 1.8e-127 radC E Belongs to the UPF0758 family
PAMDGHLD_03668 4e-184 mreB D Rod shape-determining protein MreB
PAMDGHLD_03669 1.2e-157 mreC M Involved in formation and maintenance of cell shape
PAMDGHLD_03670 1.4e-84 mreD M shape-determining protein
PAMDGHLD_03671 4.3e-105 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PAMDGHLD_03672 2.3e-142 minD D Belongs to the ParA family
PAMDGHLD_03673 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
PAMDGHLD_03674 7.8e-160 spoIVFB S Stage IV sporulation protein
PAMDGHLD_03675 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
PAMDGHLD_03676 3.2e-56 ysxB J ribosomal protein
PAMDGHLD_03677 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PAMDGHLD_03678 4.8e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
PAMDGHLD_03679 2.2e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PAMDGHLD_03680 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
PAMDGHLD_03681 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
PAMDGHLD_03682 1.9e-92 niaR S small molecule binding protein (contains 3H domain)
PAMDGHLD_03683 9.5e-222 nifS 2.8.1.7 E Cysteine desulfurase
PAMDGHLD_03684 1e-298 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
PAMDGHLD_03685 2.2e-151 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
PAMDGHLD_03686 1.6e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PAMDGHLD_03687 1.7e-144 safA M spore coat assembly protein SafA
PAMDGHLD_03688 1.4e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PAMDGHLD_03690 1.4e-92 bofC S BofC C-terminal domain
PAMDGHLD_03691 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PAMDGHLD_03692 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PAMDGHLD_03693 1.6e-20 yrzS S Protein of unknown function (DUF2905)
PAMDGHLD_03694 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PAMDGHLD_03695 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PAMDGHLD_03696 5.6e-37 yajC U Preprotein translocase subunit YajC
PAMDGHLD_03697 2.4e-60 yrzE S Protein of unknown function (DUF3792)
PAMDGHLD_03698 6.2e-109 yrbG S membrane
PAMDGHLD_03699 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PAMDGHLD_03700 1.3e-50 yrzD S Post-transcriptional regulator
PAMDGHLD_03701 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PAMDGHLD_03702 2.1e-85 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
PAMDGHLD_03703 5.7e-47 yrvD S Lipopolysaccharide assembly protein A domain
PAMDGHLD_03704 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PAMDGHLD_03705 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PAMDGHLD_03706 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PAMDGHLD_03707 6.7e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PAMDGHLD_03708 3.4e-275 lytH 3.5.1.28 M COG3103 SH3 domain protein
PAMDGHLD_03711 2.8e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
PAMDGHLD_03712 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PAMDGHLD_03713 1.3e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PAMDGHLD_03714 1.7e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PAMDGHLD_03715 7.8e-64 cymR K Transcriptional regulator
PAMDGHLD_03716 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
PAMDGHLD_03717 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PAMDGHLD_03718 1.7e-18 S COG0457 FOG TPR repeat
PAMDGHLD_03719 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PAMDGHLD_03720 3.2e-80 yrrD S protein conserved in bacteria
PAMDGHLD_03721 2.9e-30 yrzR
PAMDGHLD_03722 2.1e-08 S Protein of unknown function (DUF3918)
PAMDGHLD_03723 9.9e-107 glnP P ABC transporter
PAMDGHLD_03724 3.6e-109 gluC P ABC transporter
PAMDGHLD_03725 3.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
PAMDGHLD_03726 2e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PAMDGHLD_03727 1.4e-163 yrrI S AI-2E family transporter
PAMDGHLD_03728 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PAMDGHLD_03729 1.7e-41 yrzL S Belongs to the UPF0297 family
PAMDGHLD_03730 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PAMDGHLD_03731 7.1e-46 yrzB S Belongs to the UPF0473 family
PAMDGHLD_03732 8.2e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PAMDGHLD_03733 9.5e-118 yrrM 2.1.1.104 S O-methyltransferase
PAMDGHLD_03734 5.6e-172 yegQ O Peptidase U32
PAMDGHLD_03735 6.1e-246 yegQ O COG0826 Collagenase and related proteases
PAMDGHLD_03736 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
PAMDGHLD_03737 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PAMDGHLD_03738 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
PAMDGHLD_03739 8.9e-69 yrrS S Protein of unknown function (DUF1510)
PAMDGHLD_03740 4.1e-27 yrzA S Protein of unknown function (DUF2536)
PAMDGHLD_03741 2.1e-117 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
PAMDGHLD_03742 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PAMDGHLD_03743 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
PAMDGHLD_03744 2.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PAMDGHLD_03745 3.9e-34 yrhC S YrhC-like protein
PAMDGHLD_03746 3.8e-79 yrhD S Protein of unknown function (DUF1641)
PAMDGHLD_03747 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
PAMDGHLD_03748 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
PAMDGHLD_03749 8e-143 focA P Formate nitrite
PAMDGHLD_03751 3.9e-93 yrhH Q methyltransferase
PAMDGHLD_03752 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
PAMDGHLD_03753 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
PAMDGHLD_03754 6.9e-215 ynfM EGP Major facilitator Superfamily
PAMDGHLD_03755 2.6e-163 yybE K Transcriptional regulator
PAMDGHLD_03756 6.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PAMDGHLD_03757 1.2e-182 romA S Beta-lactamase superfamily domain
PAMDGHLD_03758 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
PAMDGHLD_03759 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
PAMDGHLD_03760 3.3e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
PAMDGHLD_03761 1.6e-129 glvR K Helix-turn-helix domain, rpiR family
PAMDGHLD_03762 1.7e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
PAMDGHLD_03763 4.1e-147 S hydrolase
PAMDGHLD_03764 8.9e-92 yrdA S DinB family
PAMDGHLD_03765 3.3e-81 yyaR K Acetyltransferase (GNAT) domain
PAMDGHLD_03766 5.1e-222 tetL EGP Major facilitator Superfamily
PAMDGHLD_03767 9.2e-26 yyaR K acetyltransferase
PAMDGHLD_03768 2.6e-97 adk 2.7.4.3 F adenylate kinase activity
PAMDGHLD_03769 1.9e-103 yrkN K Acetyltransferase (GNAT) family
PAMDGHLD_03771 9.4e-220 yrkO P Protein of unknown function (DUF418)
PAMDGHLD_03773 1.6e-123 T Transcriptional regulator
PAMDGHLD_03774 1.1e-237 yrkQ T Histidine kinase
PAMDGHLD_03775 3e-69 psiE S Belongs to the PsiE family
PAMDGHLD_03776 2e-89 K Transcriptional regulator PadR-like family
PAMDGHLD_03777 1.2e-157 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
PAMDGHLD_03779 1.9e-53 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAMDGHLD_03780 2.9e-46 D nuclear chromosome segregation
PAMDGHLD_03781 4.5e-60 L Transposase
PAMDGHLD_03782 6e-58 yjcP
PAMDGHLD_03783 7.2e-46 S YjcQ protein
PAMDGHLD_03784 3.6e-20
PAMDGHLD_03785 6.5e-70 K MerR family transcriptional regulator
PAMDGHLD_03786 8.2e-138 yvgN 1.1.1.346 S Aldo/keto reductase family
PAMDGHLD_03788 1.8e-19 xkdR S Protein of unknown function (DUF2577)
PAMDGHLD_03789 3.9e-109 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PAMDGHLD_03790 4.5e-26 xkdS S Protein of unknown function (DUF2634)
PAMDGHLD_03791 2.7e-36 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAMDGHLD_03792 1.3e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PAMDGHLD_03793 4.3e-220 EGP Major facilitator Superfamily
PAMDGHLD_03794 9.3e-25 2.3.1.57 K Acetyltransferase (GNAT) domain
PAMDGHLD_03795 3.4e-107 yqeD S SNARE associated Golgi protein
PAMDGHLD_03796 4e-141 3.5.1.104 G Polysaccharide deacetylase
PAMDGHLD_03797 1.6e-137 yqeF E GDSL-like Lipase/Acylhydrolase
PAMDGHLD_03799 2e-94 yqeG S hydrolase of the HAD superfamily
PAMDGHLD_03800 1e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PAMDGHLD_03801 5.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PAMDGHLD_03802 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
PAMDGHLD_03803 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PAMDGHLD_03804 6.4e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PAMDGHLD_03805 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PAMDGHLD_03806 4.2e-138 yqeM Q Methyltransferase
PAMDGHLD_03807 2.2e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAMDGHLD_03808 6.2e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PAMDGHLD_03809 8e-105 comEB 3.5.4.12 F ComE operon protein 2
PAMDGHLD_03810 0.0 comEC S Competence protein ComEC
PAMDGHLD_03811 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
PAMDGHLD_03812 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
PAMDGHLD_03813 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PAMDGHLD_03814 9.2e-220 spoIIP M stage II sporulation protein P
PAMDGHLD_03815 3.8e-54 yqxA S Protein of unknown function (DUF3679)
PAMDGHLD_03816 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PAMDGHLD_03817 5.9e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
PAMDGHLD_03818 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PAMDGHLD_03819 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PAMDGHLD_03820 0.0 dnaK O Heat shock 70 kDa protein
PAMDGHLD_03821 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PAMDGHLD_03822 7.8e-174 prmA J Methylates ribosomal protein L11
PAMDGHLD_03823 2.3e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PAMDGHLD_03824 1e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
PAMDGHLD_03825 1e-157 yqeW P COG1283 Na phosphate symporter
PAMDGHLD_03826 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PAMDGHLD_03827 1.2e-68 yqeY S Yqey-like protein
PAMDGHLD_03828 2.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
PAMDGHLD_03829 1.2e-119 yqfA S UPF0365 protein
PAMDGHLD_03830 4.6e-36 yqfB
PAMDGHLD_03831 9.3e-46 yqfC S sporulation protein YqfC
PAMDGHLD_03832 6.8e-215 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
PAMDGHLD_03833 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
PAMDGHLD_03834 0.0 yqfF S membrane-associated HD superfamily hydrolase
PAMDGHLD_03835 5.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PAMDGHLD_03836 4.6e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PAMDGHLD_03837 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PAMDGHLD_03838 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PAMDGHLD_03839 1.8e-16 S YqzL-like protein
PAMDGHLD_03840 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
PAMDGHLD_03841 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PAMDGHLD_03842 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PAMDGHLD_03843 4.5e-112 ccpN K CBS domain
PAMDGHLD_03844 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PAMDGHLD_03845 1.8e-87 yaiI S Belongs to the UPF0178 family
PAMDGHLD_03846 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PAMDGHLD_03847 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PAMDGHLD_03848 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)