ORF_ID e_value Gene_name EC_number CAZy COGs Description
ECDMHAGH_00001 5.3e-131 L PFAM transposase, IS4 family protein
ECDMHAGH_00003 3.1e-49
ECDMHAGH_00004 2e-68
ECDMHAGH_00005 7.9e-196 lplA 6.3.1.20 H Lipoate-protein ligase
ECDMHAGH_00006 1.6e-79 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
ECDMHAGH_00007 6.9e-192 oppD P Belongs to the ABC transporter superfamily
ECDMHAGH_00008 2.9e-179 oppF P Belongs to the ABC transporter superfamily
ECDMHAGH_00009 9.8e-180 oppB P ABC transporter permease
ECDMHAGH_00010 1e-173 oppC EP Binding-protein-dependent transport system inner membrane component
ECDMHAGH_00011 0.0 oppA1 E ABC transporter substrate-binding protein
ECDMHAGH_00012 6.9e-50 K transcriptional regulator
ECDMHAGH_00013 6e-164 norB EGP Major Facilitator
ECDMHAGH_00014 8.6e-107 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ECDMHAGH_00015 2.8e-76 uspA T universal stress protein
ECDMHAGH_00016 1.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ECDMHAGH_00018 2.5e-127 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
ECDMHAGH_00019 3.1e-208 2.1.1.80, 2.7.13.3, 3.1.1.61 T protein histidine kinase activity
ECDMHAGH_00020 1e-211 2.7.13.3 T GHKL domain
ECDMHAGH_00021 8.6e-122 plnC K LytTr DNA-binding domain
ECDMHAGH_00022 3.3e-71
ECDMHAGH_00023 7.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ECDMHAGH_00024 1.6e-107 O Zinc-dependent metalloprotease
ECDMHAGH_00025 4.4e-132 gntR1 K UbiC transcription regulator-associated domain protein
ECDMHAGH_00026 3.2e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECDMHAGH_00027 1.5e-128
ECDMHAGH_00028 1.3e-64 S Leucine-rich repeat (LRR) protein
ECDMHAGH_00029 2.2e-19 K Helix-turn-helix XRE-family like proteins
ECDMHAGH_00030 2.8e-19 S Protein of unknown function (DUF3278)
ECDMHAGH_00031 4e-251 EGP Major facilitator Superfamily
ECDMHAGH_00033 1.8e-226 S module of peptide synthetase
ECDMHAGH_00034 2e-293 uxaC 5.3.1.12 G glucuronate isomerase
ECDMHAGH_00035 4.8e-309 5.1.2.7 S tagaturonate epimerase
ECDMHAGH_00036 1.8e-278 yjmB G MFS/sugar transport protein
ECDMHAGH_00037 2.4e-184 exuR K Periplasmic binding protein domain
ECDMHAGH_00038 3.3e-208 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
ECDMHAGH_00039 9.8e-129 kdgR K FCD domain
ECDMHAGH_00040 3.9e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
ECDMHAGH_00041 3.9e-303 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
ECDMHAGH_00042 1.6e-188 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECDMHAGH_00043 1.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
ECDMHAGH_00044 1.3e-165 yqhA G Aldose 1-epimerase
ECDMHAGH_00045 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
ECDMHAGH_00046 6.4e-204 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
ECDMHAGH_00047 1.1e-92 kdgR K FCD domain
ECDMHAGH_00048 2.2e-266 uxuT G MFS/sugar transport protein
ECDMHAGH_00049 2.8e-34
ECDMHAGH_00050 3.5e-242 uxaC 5.3.1.12 G glucuronate isomerase
ECDMHAGH_00051 1.8e-109 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
ECDMHAGH_00052 9.9e-83 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
ECDMHAGH_00053 1.5e-149 gntP EG GntP family permease
ECDMHAGH_00054 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
ECDMHAGH_00055 0.0 yicI 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
ECDMHAGH_00056 1.8e-259 gph G MFS/sugar transport protein
ECDMHAGH_00057 2.8e-284 uxaC 5.3.1.12 G glucuronate isomerase
ECDMHAGH_00058 4.4e-247 V Polysaccharide biosynthesis C-terminal domain
ECDMHAGH_00059 5.6e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
ECDMHAGH_00060 9.4e-169 yjjC V ABC transporter
ECDMHAGH_00061 1.9e-284 M Exporter of polyketide antibiotics
ECDMHAGH_00062 8.7e-47 DR0488 S 3D domain
ECDMHAGH_00063 1.6e-216 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECDMHAGH_00064 7.4e-175 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
ECDMHAGH_00065 1.4e-166 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ECDMHAGH_00066 5.6e-89 K Bacterial regulatory proteins, tetR family
ECDMHAGH_00068 6.5e-57 M LysM domain
ECDMHAGH_00070 6e-56 M LysM domain protein
ECDMHAGH_00071 3.8e-46 M LysM domain protein
ECDMHAGH_00072 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
ECDMHAGH_00073 0.0 glpQ 3.1.4.46 C phosphodiesterase
ECDMHAGH_00074 8.5e-93 M1-874 K Domain of unknown function (DUF1836)
ECDMHAGH_00075 0.0 yfgQ P E1-E2 ATPase
ECDMHAGH_00077 3.6e-162 ytbE 1.1.1.346 S Aldo keto reductase
ECDMHAGH_00078 8.9e-257 yjeM E Amino Acid
ECDMHAGH_00079 3.5e-73 hsp O Belongs to the small heat shock protein (HSP20) family
ECDMHAGH_00080 7.6e-61
ECDMHAGH_00081 3.3e-242 yhdP S Transporter associated domain
ECDMHAGH_00082 1.6e-106 yneD S Enoyl-(Acyl carrier protein) reductase
ECDMHAGH_00083 7.6e-52 K transcriptional regulator
ECDMHAGH_00084 5.2e-173 K Transcriptional regulator, LacI family
ECDMHAGH_00085 7.7e-143 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ECDMHAGH_00087 6e-250 lmrB EGP Major facilitator Superfamily
ECDMHAGH_00088 3e-255 S ATPases associated with a variety of cellular activities
ECDMHAGH_00089 4.5e-85 nrdI F Belongs to the NrdI family
ECDMHAGH_00090 1.2e-129 nfrA 1.5.1.39 C nitroreductase
ECDMHAGH_00091 2.7e-27 K Bacterial regulatory proteins, tetR family
ECDMHAGH_00092 9e-92 emrY EGP Major facilitator Superfamily
ECDMHAGH_00093 5.3e-38 ywnB S NAD(P)H-binding
ECDMHAGH_00094 7.1e-245 glpT G Major Facilitator Superfamily
ECDMHAGH_00095 2.3e-215 yttB EGP Major facilitator Superfamily
ECDMHAGH_00096 1.2e-88
ECDMHAGH_00097 2.7e-114 tra L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_00098 1.2e-48 KLT serine threonine protein kinase
ECDMHAGH_00099 4.8e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ECDMHAGH_00100 2.4e-83 ytsP 1.8.4.14 T GAF domain-containing protein
ECDMHAGH_00101 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ECDMHAGH_00102 7.2e-214 iscS2 2.8.1.7 E Aminotransferase class V
ECDMHAGH_00103 7.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECDMHAGH_00104 3.5e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ECDMHAGH_00105 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ECDMHAGH_00106 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ECDMHAGH_00107 2.1e-117 radC L DNA repair protein
ECDMHAGH_00108 9.6e-162 mreB D cell shape determining protein MreB
ECDMHAGH_00109 9.7e-139 mreC M Involved in formation and maintenance of cell shape
ECDMHAGH_00110 3.2e-92 mreD M rod shape-determining protein MreD
ECDMHAGH_00111 8.2e-117 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
ECDMHAGH_00112 4.1e-147 minD D Belongs to the ParA family
ECDMHAGH_00113 2.5e-110 glnP P ABC transporter permease
ECDMHAGH_00114 1.2e-93 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ECDMHAGH_00115 3.7e-159 aatB ET ABC transporter substrate-binding protein
ECDMHAGH_00116 4.2e-234 ymfF S Peptidase M16 inactive domain protein
ECDMHAGH_00117 1.1e-245 ymfH S Peptidase M16
ECDMHAGH_00118 2.6e-65 ymfM S Domain of unknown function (DUF4115)
ECDMHAGH_00119 1e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECDMHAGH_00120 1.6e-227 cinA 3.5.1.42 S Belongs to the CinA family
ECDMHAGH_00121 4.7e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ECDMHAGH_00123 4e-223 rny S Endoribonuclease that initiates mRNA decay
ECDMHAGH_00124 1.5e-149 ymdB S YmdB-like protein
ECDMHAGH_00125 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ECDMHAGH_00126 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ECDMHAGH_00127 2.8e-108 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ECDMHAGH_00128 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ECDMHAGH_00129 4.1e-200 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ECDMHAGH_00130 2.6e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ECDMHAGH_00131 1.1e-26 yajC U Preprotein translocase
ECDMHAGH_00132 1.9e-179 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ECDMHAGH_00133 1.5e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
ECDMHAGH_00134 6.1e-252 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ECDMHAGH_00135 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ECDMHAGH_00136 1.9e-43 yrzL S Belongs to the UPF0297 family
ECDMHAGH_00137 1.5e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ECDMHAGH_00138 1.6e-51 yrzB S Belongs to the UPF0473 family
ECDMHAGH_00139 1.2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ECDMHAGH_00140 3.2e-87 cvpA S Colicin V production protein
ECDMHAGH_00141 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ECDMHAGH_00142 2.7e-54 trxA O Belongs to the thioredoxin family
ECDMHAGH_00143 2.2e-88 yslB S Protein of unknown function (DUF2507)
ECDMHAGH_00144 4.7e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ECDMHAGH_00145 3.1e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ECDMHAGH_00146 5.6e-97 S Phosphoesterase
ECDMHAGH_00147 4.5e-80 ykuL S (CBS) domain
ECDMHAGH_00148 4.3e-15
ECDMHAGH_00149 4.9e-23 S Mor transcription activator family
ECDMHAGH_00150 6e-46 S virion core protein, lumpy skin disease virus
ECDMHAGH_00151 2.1e-72 bla2 3.5.2.6 V Beta-lactamase enzyme family
ECDMHAGH_00152 4.2e-134 S Protease prsW family
ECDMHAGH_00154 9.8e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
ECDMHAGH_00155 2.3e-243 U Major Facilitator Superfamily
ECDMHAGH_00157 4.1e-156 ykuT M mechanosensitive ion channel
ECDMHAGH_00158 6.9e-34 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ECDMHAGH_00159 9.5e-43
ECDMHAGH_00160 2.7e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ECDMHAGH_00161 4.6e-180 ccpA K catabolite control protein A
ECDMHAGH_00163 2.6e-12 ps115 K Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators
ECDMHAGH_00165 4.8e-97 S Phage regulatory protein
ECDMHAGH_00167 4.4e-23 S Domain of unknown function (DUF1883)
ECDMHAGH_00168 9.8e-53 M Glycosyl transferases group 1
ECDMHAGH_00169 7.8e-09 1.1.1.133 S Glycosyltransferase like family 2
ECDMHAGH_00170 2.1e-57 glfT1 1.1.1.133 S Glycosyltransferase like family 2
ECDMHAGH_00172 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ECDMHAGH_00173 3.8e-75 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ECDMHAGH_00174 7.8e-64 K Transcriptional regulator
ECDMHAGH_00175 2.1e-99 S Phosphatidylethanolamine-binding protein
ECDMHAGH_00176 7.1e-218 EGP Major facilitator Superfamily
ECDMHAGH_00177 7.9e-298 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
ECDMHAGH_00181 2.6e-64 S Plasmid replication protein
ECDMHAGH_00182 5.4e-140 K Bacterial regulatory helix-turn-helix protein, lysR family
ECDMHAGH_00183 5.3e-120 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ECDMHAGH_00184 6.6e-72 repA S Replication initiator protein A
ECDMHAGH_00185 3.8e-210 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
ECDMHAGH_00186 6.1e-171 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
ECDMHAGH_00187 1.4e-07 mod 2.1.1.72, 3.1.21.5 L DNA methylase
ECDMHAGH_00188 7.3e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ECDMHAGH_00189 3.4e-194 htrA 3.4.21.107 O serine protease
ECDMHAGH_00190 3.4e-157 vicX 3.1.26.11 S domain protein
ECDMHAGH_00191 6.1e-149 yycI S YycH protein
ECDMHAGH_00192 1.1e-237 yycH S YycH protein
ECDMHAGH_00193 0.0 vicK 2.7.13.3 T Histidine kinase
ECDMHAGH_00194 5.7e-132 K response regulator
ECDMHAGH_00196 8.2e-113 E Matrixin
ECDMHAGH_00197 4.5e-36
ECDMHAGH_00198 1.5e-302 E ABC transporter, substratebinding protein
ECDMHAGH_00199 8.9e-22
ECDMHAGH_00200 5e-210 yttB EGP Major facilitator Superfamily
ECDMHAGH_00201 8.5e-101 S NADPH-dependent FMN reductase
ECDMHAGH_00202 6e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ECDMHAGH_00205 1.2e-63 rplI J Binds to the 23S rRNA
ECDMHAGH_00206 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
ECDMHAGH_00207 3.2e-66 S membrane transporter protein
ECDMHAGH_00208 1.1e-98 K Bacterial regulatory proteins, tetR family
ECDMHAGH_00209 4e-303 E ABC transporter, substratebinding protein
ECDMHAGH_00210 4.8e-229 Q Imidazolonepropionase and related amidohydrolases
ECDMHAGH_00211 6.9e-139
ECDMHAGH_00212 4e-303 E ABC transporter, substratebinding protein
ECDMHAGH_00213 6.8e-231 Q Imidazolonepropionase and related amidohydrolases
ECDMHAGH_00214 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ECDMHAGH_00215 3.9e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ECDMHAGH_00216 1.9e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
ECDMHAGH_00217 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECDMHAGH_00218 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECDMHAGH_00219 1.7e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ECDMHAGH_00220 2e-35 yaaA S S4 domain protein YaaA
ECDMHAGH_00221 8.5e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ECDMHAGH_00222 4.8e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ECDMHAGH_00223 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
ECDMHAGH_00224 3.2e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ECDMHAGH_00225 1e-145 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ECDMHAGH_00226 1e-110 jag S R3H domain protein
ECDMHAGH_00227 7.1e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ECDMHAGH_00228 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ECDMHAGH_00229 4.4e-54
ECDMHAGH_00230 3e-37
ECDMHAGH_00231 1.1e-107 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
ECDMHAGH_00232 1.4e-35
ECDMHAGH_00233 1.6e-244 brnQ U Component of the transport system for branched-chain amino acids
ECDMHAGH_00234 3.1e-113 ywnB S NAD(P)H-binding
ECDMHAGH_00235 4e-98 J Acetyltransferase (GNAT) domain
ECDMHAGH_00236 1.2e-91 ykhA 3.1.2.20 I Thioesterase superfamily
ECDMHAGH_00237 1.6e-224 S module of peptide synthetase
ECDMHAGH_00238 2.7e-217 tcaB EGP Major facilitator Superfamily
ECDMHAGH_00239 5.5e-109 lepB 3.4.21.89 U Belongs to the peptidase S26 family
ECDMHAGH_00240 1.3e-76 K helix_turn_helix multiple antibiotic resistance protein
ECDMHAGH_00241 1.9e-250 pepC 3.4.22.40 E aminopeptidase
ECDMHAGH_00242 2.2e-111 L haloacid dehalogenase-like hydrolase
ECDMHAGH_00243 8.8e-50
ECDMHAGH_00247 1.1e-218 ydiC1 EGP Major facilitator Superfamily
ECDMHAGH_00248 1.6e-163 corA P CorA-like Mg2+ transporter protein
ECDMHAGH_00249 2.2e-127
ECDMHAGH_00250 1e-125 liaI S membrane
ECDMHAGH_00252 6.3e-31
ECDMHAGH_00255 1.1e-31 K Helix-turn-helix XRE-family like proteins
ECDMHAGH_00256 1.5e-86 K helix_turn_helix multiple antibiotic resistance protein
ECDMHAGH_00257 0.0 pepO 3.4.24.71 O Peptidase family M13
ECDMHAGH_00258 2.8e-91 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
ECDMHAGH_00259 3.4e-21
ECDMHAGH_00261 1.8e-31 V AAA domain, putative AbiEii toxin, Type IV TA system
ECDMHAGH_00263 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
ECDMHAGH_00265 6.2e-185 galR K Transcriptional regulator
ECDMHAGH_00266 1.4e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ECDMHAGH_00267 4.4e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ECDMHAGH_00268 1.9e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ECDMHAGH_00269 9.3e-211 gph G Transporter
ECDMHAGH_00270 2.6e-36
ECDMHAGH_00271 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
ECDMHAGH_00272 1.2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
ECDMHAGH_00273 6.4e-207 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
ECDMHAGH_00274 3.2e-144 etfB C Electron transfer flavoprotein domain
ECDMHAGH_00275 4e-173 etfA C Electron transfer flavoprotein FAD-binding domain
ECDMHAGH_00276 1.1e-89 1.1.1.1 C nadph quinone reductase
ECDMHAGH_00277 1.2e-72 1.1.1.1 C nadph quinone reductase
ECDMHAGH_00278 3.2e-53 K Transcriptional
ECDMHAGH_00279 4.9e-125 hchA 3.5.1.124 S DJ-1/PfpI family
ECDMHAGH_00280 0.0 oppD EP Psort location Cytoplasmic, score
ECDMHAGH_00281 5e-77 K Transcriptional regulator, LysR family
ECDMHAGH_00282 4.6e-190 oxlT G Major Facilitator Superfamily
ECDMHAGH_00283 1.5e-126 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ECDMHAGH_00284 1.3e-132 IQ Enoyl-(Acyl carrier protein) reductase
ECDMHAGH_00285 1.1e-80 6.3.3.2 S ASCH
ECDMHAGH_00286 5.2e-246 EGP Major facilitator Superfamily
ECDMHAGH_00287 2.3e-23
ECDMHAGH_00288 5.5e-152 map 3.4.11.18 E Methionine Aminopeptidase
ECDMHAGH_00289 1.1e-138 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ECDMHAGH_00290 1.4e-158 hipB K Helix-turn-helix
ECDMHAGH_00291 1.8e-118 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
ECDMHAGH_00292 7.5e-70 yeaO S Protein of unknown function, DUF488
ECDMHAGH_00293 1.4e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S HAD-hyrolase-like
ECDMHAGH_00294 2.3e-78 usp1 T Universal stress protein family
ECDMHAGH_00295 1e-208 U Belongs to the BCCT transporter (TC 2.A.15) family
ECDMHAGH_00296 2.4e-44 U Belongs to the BCCT transporter (TC 2.A.15) family
ECDMHAGH_00297 1.8e-110 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
ECDMHAGH_00298 2.5e-83 S 3-demethylubiquinone-9 3-methyltransferase
ECDMHAGH_00299 7.9e-143 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ECDMHAGH_00300 1.3e-84
ECDMHAGH_00301 6.4e-240 codA 3.5.4.1 F cytosine deaminase
ECDMHAGH_00302 5.2e-47
ECDMHAGH_00303 1.2e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ECDMHAGH_00304 5.2e-18
ECDMHAGH_00305 1.2e-123 yrkL S Flavodoxin-like fold
ECDMHAGH_00307 6.2e-30
ECDMHAGH_00309 1e-37 S Cytochrome B5
ECDMHAGH_00310 2.1e-31 cspC K Cold shock protein
ECDMHAGH_00311 1.1e-107 XK27_00220 S Dienelactone hydrolase family
ECDMHAGH_00312 9.9e-52
ECDMHAGH_00313 8.8e-220 mutY L A G-specific adenine glycosylase
ECDMHAGH_00314 1.9e-303 E Bacterial extracellular solute-binding proteins, family 5 Middle
ECDMHAGH_00315 0.0 pelX M domain, Protein
ECDMHAGH_00316 4.8e-51
ECDMHAGH_00317 1.1e-189 6.3.1.20 H Lipoate-protein ligase
ECDMHAGH_00318 6.3e-66 gcvH E glycine cleavage
ECDMHAGH_00319 9.7e-183 tas C Aldo/keto reductase family
ECDMHAGH_00320 2.1e-32
ECDMHAGH_00321 1.6e-177 EG EamA-like transporter family
ECDMHAGH_00322 6.7e-63 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
ECDMHAGH_00323 1.5e-18 L transposase and inactivated derivatives, IS30 family
ECDMHAGH_00324 9.6e-07 S regulation of response to stimulus
ECDMHAGH_00326 1e-38 L Transposase
ECDMHAGH_00327 9.1e-197 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
ECDMHAGH_00328 2.9e-51
ECDMHAGH_00329 1.7e-58
ECDMHAGH_00330 3.7e-207
ECDMHAGH_00331 4.9e-99 K DNA-templated transcription, initiation
ECDMHAGH_00332 2.3e-27
ECDMHAGH_00333 4.8e-11 S Protein of unknown function (DUF2922)
ECDMHAGH_00334 4.9e-165 K LysR substrate binding domain
ECDMHAGH_00335 1.5e-225 EK Aminotransferase, class I
ECDMHAGH_00336 2.2e-66
ECDMHAGH_00337 4.2e-49 L Transposase IS200 like
ECDMHAGH_00338 7.6e-210
ECDMHAGH_00340 1.1e-288
ECDMHAGH_00341 1.4e-105
ECDMHAGH_00342 5.5e-35
ECDMHAGH_00343 1.1e-62 K HxlR-like helix-turn-helix
ECDMHAGH_00344 1.6e-39
ECDMHAGH_00345 3.8e-86
ECDMHAGH_00346 6.3e-44
ECDMHAGH_00347 3.1e-113 GM NmrA-like family
ECDMHAGH_00348 7.9e-154 5.4.2.7 G Metalloenzyme superfamily
ECDMHAGH_00349 5.3e-226 nupG F Nucleoside
ECDMHAGH_00350 1.3e-214 pbuO_1 S Permease family
ECDMHAGH_00351 2.8e-168 rihC 3.2.2.1, 3.2.2.8 F Nucleoside
ECDMHAGH_00352 1.1e-164 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
ECDMHAGH_00353 1.7e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
ECDMHAGH_00354 1.2e-146 noc K Belongs to the ParB family
ECDMHAGH_00355 4.1e-136 soj D Sporulation initiation inhibitor
ECDMHAGH_00356 3.4e-155 spo0J K Belongs to the ParB family
ECDMHAGH_00357 8.5e-33 yyzM S Bacterial protein of unknown function (DUF951)
ECDMHAGH_00358 8.3e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ECDMHAGH_00359 3.1e-133 XK27_01040 S Protein of unknown function (DUF1129)
ECDMHAGH_00360 8.8e-107
ECDMHAGH_00361 3.7e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ECDMHAGH_00362 3.5e-123 K response regulator
ECDMHAGH_00363 7.4e-214 hpk31 2.7.13.3 T Histidine kinase
ECDMHAGH_00364 1.5e-239 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ECDMHAGH_00365 2e-215 V domain protein
ECDMHAGH_00366 4.3e-35
ECDMHAGH_00367 1.6e-249 gor 1.8.1.7 C Glutathione reductase
ECDMHAGH_00368 2.1e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
ECDMHAGH_00369 7.2e-136 azlC E AzlC protein
ECDMHAGH_00370 1.3e-52 azlD S branched-chain amino acid
ECDMHAGH_00371 5.4e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
ECDMHAGH_00372 3e-122
ECDMHAGH_00373 1.5e-214 xylR GK ROK family
ECDMHAGH_00374 5.2e-169 K AI-2E family transporter
ECDMHAGH_00375 3.1e-262 M domain protein
ECDMHAGH_00376 1.2e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ECDMHAGH_00377 2.5e-80 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
ECDMHAGH_00378 1.7e-38
ECDMHAGH_00379 5.2e-35 S Protein of unknown function (DUF3781)
ECDMHAGH_00380 4.4e-72 rmeB K helix_turn_helix, mercury resistance
ECDMHAGH_00381 4.6e-45 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
ECDMHAGH_00382 8.6e-106 S Aldo keto reductase
ECDMHAGH_00383 1.3e-123 degV S DegV family
ECDMHAGH_00384 2.6e-112 yjbH Q Thioredoxin
ECDMHAGH_00385 3.3e-118 yjbM 2.7.6.5 S RelA SpoT domain protein
ECDMHAGH_00386 6.8e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ECDMHAGH_00387 3.5e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
ECDMHAGH_00388 2.4e-48 3.1.3.18 S Pfam Methyltransferase
ECDMHAGH_00389 1.1e-101 S Pfam Methyltransferase
ECDMHAGH_00390 1.7e-25
ECDMHAGH_00391 3.5e-264 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
ECDMHAGH_00392 3.4e-264 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
ECDMHAGH_00393 3.8e-17 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
ECDMHAGH_00394 1.1e-107 cutC P Participates in the control of copper homeostasis
ECDMHAGH_00395 6e-203 XK27_05220 S AI-2E family transporter
ECDMHAGH_00396 3.2e-158 rrmA 2.1.1.187 H Methyltransferase
ECDMHAGH_00397 2.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ECDMHAGH_00398 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
ECDMHAGH_00399 2.2e-12 S Protein of unknown function (DUF4044)
ECDMHAGH_00400 2.9e-60 S Protein of unknown function (DUF3397)
ECDMHAGH_00401 2e-79 mraZ K Belongs to the MraZ family
ECDMHAGH_00402 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ECDMHAGH_00403 3.2e-60 ftsL D Cell division protein FtsL
ECDMHAGH_00404 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
ECDMHAGH_00405 3.3e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ECDMHAGH_00406 2.4e-248 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ECDMHAGH_00407 3.7e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ECDMHAGH_00408 2.2e-146 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ECDMHAGH_00409 6e-244 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ECDMHAGH_00410 1.1e-215 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ECDMHAGH_00411 6.5e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ECDMHAGH_00412 4.1e-41 yggT S YGGT family
ECDMHAGH_00413 5.4e-144 ylmH S S4 domain protein
ECDMHAGH_00414 7.4e-92 divIVA D DivIVA domain protein
ECDMHAGH_00415 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ECDMHAGH_00416 2.2e-34 cspA K Cold shock protein
ECDMHAGH_00417 2.5e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
ECDMHAGH_00418 5.2e-31
ECDMHAGH_00419 2.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ECDMHAGH_00420 2.6e-222 iscS 2.8.1.7 E Aminotransferase class V
ECDMHAGH_00421 1.5e-58 XK27_04120 S Putative amino acid metabolism
ECDMHAGH_00423 3e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ECDMHAGH_00424 3.5e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
ECDMHAGH_00425 3.6e-120 S Repeat protein
ECDMHAGH_00426 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ECDMHAGH_00427 1.4e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ECDMHAGH_00428 2.2e-125 yoaK S Protein of unknown function (DUF1275)
ECDMHAGH_00429 2.5e-121 yecS E ABC transporter permease
ECDMHAGH_00430 1.3e-159 yckB ET Belongs to the bacterial solute-binding protein 3 family
ECDMHAGH_00431 4e-273 nylA 3.5.1.4 J Belongs to the amidase family
ECDMHAGH_00432 3.6e-307 E ABC transporter, substratebinding protein
ECDMHAGH_00433 9.3e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ECDMHAGH_00434 9.1e-189 yghZ C Aldo keto reductase family protein
ECDMHAGH_00435 1.4e-184 rbsR K helix_turn _helix lactose operon repressor
ECDMHAGH_00436 2.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDMHAGH_00437 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECDMHAGH_00438 2.9e-170 ykfC 3.4.14.13 M NlpC/P60 family
ECDMHAGH_00439 8.8e-166 ypuA S Protein of unknown function (DUF1002)
ECDMHAGH_00440 8e-213 O AAA domain (Cdc48 subfamily)
ECDMHAGH_00441 1e-148
ECDMHAGH_00442 2.8e-63 S Phage derived protein Gp49-like (DUF891)
ECDMHAGH_00443 5.2e-41 K Helix-turn-helix domain
ECDMHAGH_00444 0.0 V Type II restriction enzyme, methylase subunits
ECDMHAGH_00445 6.1e-40
ECDMHAGH_00446 1.2e-33 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
ECDMHAGH_00447 8.3e-94 tnp2PF3 L manually curated
ECDMHAGH_00448 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDMHAGH_00449 4.6e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ECDMHAGH_00450 3.7e-233 fucP G Major Facilitator Superfamily
ECDMHAGH_00451 1.7e-171 deoR K sugar-binding domain protein
ECDMHAGH_00452 1.2e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ECDMHAGH_00453 4.2e-162 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_00454 2.2e-28 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ECDMHAGH_00455 3.8e-295 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
ECDMHAGH_00456 3.3e-239 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
ECDMHAGH_00457 1.2e-172 deoR K sugar-binding domain protein
ECDMHAGH_00458 1.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
ECDMHAGH_00459 3.8e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
ECDMHAGH_00460 1.3e-120 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ECDMHAGH_00461 5.1e-37 cro K Helix-turn-helix XRE-family like proteins
ECDMHAGH_00462 2.7e-58 K Helix-turn-helix XRE-family like proteins
ECDMHAGH_00463 3.8e-145 3.1.3.48 T Pfam:Y_phosphatase3C
ECDMHAGH_00464 5.4e-195 C Oxidoreductase
ECDMHAGH_00465 7.8e-55 pduU E BMC
ECDMHAGH_00466 4.1e-220 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECDMHAGH_00467 1.4e-209 pduQ C Iron-containing alcohol dehydrogenase
ECDMHAGH_00468 1.6e-266 pduP 1.2.1.87 C Aldehyde dehydrogenase family
ECDMHAGH_00469 1.4e-81 pduO S Haem-degrading
ECDMHAGH_00470 5.8e-103 pduO 2.5.1.17 S Cobalamin adenosyltransferase
ECDMHAGH_00471 6e-42 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
ECDMHAGH_00472 3e-90 S Putative propanediol utilisation
ECDMHAGH_00473 2.3e-113 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
ECDMHAGH_00474 4.9e-42 pduA_4 CQ BMC
ECDMHAGH_00475 4.8e-74 pduK CQ BMC
ECDMHAGH_00476 1.9e-56 pduH S Dehydratase medium subunit
ECDMHAGH_00477 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
ECDMHAGH_00478 4.5e-86 pduE 4.2.1.28 Q Dehydratase small subunit
ECDMHAGH_00479 8.5e-128 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
ECDMHAGH_00480 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
ECDMHAGH_00481 1.2e-129 pduB E BMC
ECDMHAGH_00482 5.2e-41 pduA_4 CQ BMC
ECDMHAGH_00483 4.8e-207 K helix_turn_helix, arabinose operon control protein
ECDMHAGH_00484 9.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
ECDMHAGH_00485 3.3e-42 eutP E Ethanolamine utilisation - propanediol utilisation
ECDMHAGH_00486 5.9e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ECDMHAGH_00487 9.4e-189 yegS 2.7.1.107 G Lipid kinase
ECDMHAGH_00488 3.2e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ECDMHAGH_00489 7.2e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ECDMHAGH_00490 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ECDMHAGH_00491 1.6e-181 camS S sex pheromone
ECDMHAGH_00492 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ECDMHAGH_00493 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
ECDMHAGH_00494 4.7e-213 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ECDMHAGH_00495 5.1e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ECDMHAGH_00496 2.1e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
ECDMHAGH_00497 1.6e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ECDMHAGH_00498 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ECDMHAGH_00499 1.8e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
ECDMHAGH_00500 1.1e-173 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
ECDMHAGH_00501 2.7e-282 cydA 1.10.3.14 C ubiquinol oxidase
ECDMHAGH_00502 1.9e-180 pdxB EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
ECDMHAGH_00503 7.4e-146 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ECDMHAGH_00504 3.3e-144 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ECDMHAGH_00505 4.4e-129 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
ECDMHAGH_00506 2.2e-156 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 GK Winged helix-turn-helix DNA-binding
ECDMHAGH_00507 0.0 tetP J elongation factor G
ECDMHAGH_00508 3.8e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
ECDMHAGH_00509 8.5e-156 yhaZ L DNA alkylation repair enzyme
ECDMHAGH_00510 5.9e-118 yihL K UTRA
ECDMHAGH_00511 2.1e-185 yegU O ADP-ribosylglycohydrolase
ECDMHAGH_00512 2.1e-252 F Belongs to the purine-cytosine permease (2.A.39) family
ECDMHAGH_00513 2.8e-149 G Belongs to the carbohydrate kinase PfkB family
ECDMHAGH_00514 8e-168 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
ECDMHAGH_00515 3.5e-129 S Protein of unknown function
ECDMHAGH_00516 1.2e-214 naiP EGP Major facilitator Superfamily
ECDMHAGH_00517 2.8e-115 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ECDMHAGH_00518 1.9e-107 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ECDMHAGH_00519 2.4e-103 K LysR substrate binding domain
ECDMHAGH_00520 1.4e-68 G Phosphoglycerate mutase family
ECDMHAGH_00521 3.8e-118 G PTS system sorbose-specific iic component
ECDMHAGH_00522 9.5e-153 G system, mannose fructose sorbose family IID component
ECDMHAGH_00523 3.2e-58 2.7.1.191 G PTS system fructose IIA component
ECDMHAGH_00524 3.3e-75 2.7.1.191 G PTS system sorbose subfamily IIB component
ECDMHAGH_00525 1.1e-66
ECDMHAGH_00526 1.6e-236 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECDMHAGH_00527 1e-136 S Belongs to the UPF0246 family
ECDMHAGH_00528 3.9e-10
ECDMHAGH_00530 1.4e-15 L Transposase
ECDMHAGH_00531 4.9e-29 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ECDMHAGH_00532 7e-305 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
ECDMHAGH_00533 2.8e-154 K Transcriptional regulator
ECDMHAGH_00534 3.6e-14 yjdF S Protein of unknown function (DUF2992)
ECDMHAGH_00535 6.4e-14 S Transglycosylase associated protein
ECDMHAGH_00536 3.3e-37
ECDMHAGH_00537 8.4e-303 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
ECDMHAGH_00538 7e-156 EG EamA-like transporter family
ECDMHAGH_00539 1.9e-26
ECDMHAGH_00540 1.4e-207 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
ECDMHAGH_00543 1.3e-38
ECDMHAGH_00544 1.4e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ECDMHAGH_00545 2.8e-287 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
ECDMHAGH_00546 6.4e-75 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
ECDMHAGH_00547 6.8e-262 E Amino acid permease
ECDMHAGH_00548 3.1e-238 nhaC C Na H antiporter NhaC
ECDMHAGH_00549 2.8e-196 ptcA 2.1.3.3, 2.1.3.6 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECDMHAGH_00550 7.1e-232 aguD E Amino Acid
ECDMHAGH_00551 1.1e-216 aguA 3.5.3.12 E agmatine deiminase
ECDMHAGH_00552 1.3e-165 arcC 2.7.2.2 E Belongs to the carbamate kinase family
ECDMHAGH_00553 5.2e-217 aguA 3.5.3.12 E agmatine deiminase
ECDMHAGH_00554 8.3e-148 K Helix-turn-helix domain, rpiR family
ECDMHAGH_00555 1.1e-161 mleR K LysR family
ECDMHAGH_00556 3.8e-309 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
ECDMHAGH_00557 1.5e-167 mleP S Sodium Bile acid symporter family
ECDMHAGH_00558 2.4e-81 thiW S Thiamine-precursor transporter protein (ThiW)
ECDMHAGH_00559 3.6e-17 ydiC1 EGP Major facilitator Superfamily
ECDMHAGH_00560 4.7e-91 K Transcriptional regulator PadR-like family
ECDMHAGH_00561 3e-81 merR K MerR family regulatory protein
ECDMHAGH_00562 1.4e-62 iap CBM50 M NlpC P60 family
ECDMHAGH_00563 8.3e-78 yjcF K protein acetylation
ECDMHAGH_00564 9e-124 pgm3 G phosphoglycerate mutase family
ECDMHAGH_00565 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ECDMHAGH_00566 5.4e-181 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
ECDMHAGH_00567 2.2e-142 S Alpha/beta hydrolase of unknown function (DUF915)
ECDMHAGH_00568 1e-190 S Protease prsW family
ECDMHAGH_00569 3.5e-177 iunH2 3.2.2.1, 3.2.2.8 F nucleoside hydrolase
ECDMHAGH_00570 1.6e-07 yvlA
ECDMHAGH_00571 9.7e-86
ECDMHAGH_00572 5.3e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
ECDMHAGH_00573 3.3e-152 S Alpha/beta hydrolase of unknown function (DUF915)
ECDMHAGH_00574 7.8e-233 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ECDMHAGH_00575 1.1e-73 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
ECDMHAGH_00576 8.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
ECDMHAGH_00577 3.4e-55 S LuxR family transcriptional regulator
ECDMHAGH_00578 1.8e-127 cat 2.3.1.28 V Chloramphenicol acetyltransferase
ECDMHAGH_00579 6.5e-218 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ECDMHAGH_00580 3.4e-169 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ECDMHAGH_00581 4.4e-95 S ABC transporter permease
ECDMHAGH_00582 5.7e-253 P ABC transporter
ECDMHAGH_00583 7.5e-115 P Cobalt transport protein
ECDMHAGH_00584 2.7e-120 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ECDMHAGH_00585 6.8e-10
ECDMHAGH_00586 2.2e-42
ECDMHAGH_00587 1.1e-08
ECDMHAGH_00589 5.5e-32
ECDMHAGH_00590 2.1e-216
ECDMHAGH_00591 3e-187 ansA 3.5.1.1 EJ Asparaginase
ECDMHAGH_00592 2.9e-25
ECDMHAGH_00593 4.2e-248 pbuX F xanthine permease
ECDMHAGH_00594 1.6e-168 natA S ABC transporter, ATP-binding protein
ECDMHAGH_00595 4e-210 natB CP ABC-2 family transporter protein
ECDMHAGH_00597 1.8e-251 yjjP S Putative threonine/serine exporter
ECDMHAGH_00598 1.9e-153 degV S Uncharacterised protein, DegV family COG1307
ECDMHAGH_00599 1.3e-153 1.1.1.2, 1.1.1.307 C Aldo keto reductase
ECDMHAGH_00600 3.4e-64 S Protein of unknown function (DUF1722)
ECDMHAGH_00601 7.7e-69 yqeB S Pyrimidine dimer DNA glycosylase
ECDMHAGH_00602 1e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
ECDMHAGH_00603 5.8e-126 K Crp-like helix-turn-helix domain
ECDMHAGH_00604 6.2e-238 larA 5.1.2.1 S Domain of unknown function (DUF2088)
ECDMHAGH_00605 2.1e-132 cpmA S AIR carboxylase
ECDMHAGH_00606 7.5e-225 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ECDMHAGH_00607 7.8e-149 larE S NAD synthase
ECDMHAGH_00608 1.7e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
ECDMHAGH_00609 3.2e-178 hoxN U High-affinity nickel-transport protein
ECDMHAGH_00610 4.9e-43 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
ECDMHAGH_00612 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
ECDMHAGH_00613 4.3e-36 ykuJ S Protein of unknown function (DUF1797)
ECDMHAGH_00614 4.1e-184 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ECDMHAGH_00615 5.7e-194 cpoA GT4 M Glycosyltransferase, group 1 family protein
ECDMHAGH_00616 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
ECDMHAGH_00617 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECDMHAGH_00618 2.7e-39 ptsH G phosphocarrier protein HPR
ECDMHAGH_00619 1.1e-29
ECDMHAGH_00620 0.0 clpE O Belongs to the ClpA ClpB family
ECDMHAGH_00621 1.4e-203 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
ECDMHAGH_00622 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
ECDMHAGH_00623 7.8e-282 pipD E Dipeptidase
ECDMHAGH_00624 5.9e-255 nox 1.6.3.4 C NADH oxidase
ECDMHAGH_00625 4.7e-267 XK27_00720 S Leucine-rich repeat (LRR) protein
ECDMHAGH_00626 6.5e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ECDMHAGH_00627 5e-88
ECDMHAGH_00628 0.0 2.7.8.12 M glycerophosphotransferase
ECDMHAGH_00629 3.6e-152
ECDMHAGH_00630 2.6e-76 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
ECDMHAGH_00631 1.2e-179 yueF S AI-2E family transporter
ECDMHAGH_00632 4.4e-108 ygaC J Belongs to the UPF0374 family
ECDMHAGH_00633 2.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
ECDMHAGH_00634 3.2e-217 pbpX2 V Beta-lactamase
ECDMHAGH_00635 3.6e-143 recX 2.4.1.337 GT4 S Regulatory protein RecX
ECDMHAGH_00636 1.1e-77 fld C Flavodoxin
ECDMHAGH_00637 1.7e-157 yihY S Belongs to the UPF0761 family
ECDMHAGH_00638 2.1e-157 S Nuclease-related domain
ECDMHAGH_00639 1.9e-211 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ECDMHAGH_00640 2.5e-159 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
ECDMHAGH_00641 4.1e-232 gntP EG Gluconate
ECDMHAGH_00642 5.6e-77 T Universal stress protein family
ECDMHAGH_00645 1.6e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
ECDMHAGH_00646 7.3e-186 mocA S Oxidoreductase
ECDMHAGH_00647 5.7e-64 S Domain of unknown function (DUF4828)
ECDMHAGH_00648 1.6e-145 lys M Glycosyl hydrolases family 25
ECDMHAGH_00649 3.2e-150 gntR K rpiR family
ECDMHAGH_00650 4.6e-304 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
ECDMHAGH_00651 3.4e-92
ECDMHAGH_00652 4.6e-67 S sequence-specific DNA binding
ECDMHAGH_00653 1e-11
ECDMHAGH_00654 1.8e-53 K Phage antirepressor protein KilAC domain
ECDMHAGH_00662 7e-31 S ERF superfamily
ECDMHAGH_00663 1.3e-51 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ECDMHAGH_00664 9.3e-95 S Pfam:HNHc_6
ECDMHAGH_00665 4.3e-47 S calcium ion binding
ECDMHAGH_00666 1.6e-71 pi346 L IstB-like ATP binding protein
ECDMHAGH_00672 1.6e-10 S YopX protein
ECDMHAGH_00674 2.4e-08 K Transcriptional regulator
ECDMHAGH_00675 1.4e-45 S Transcriptional regulator, RinA family
ECDMHAGH_00677 1.1e-27
ECDMHAGH_00678 1.2e-63 L Terminase small subunit
ECDMHAGH_00679 5.3e-160 ps334 S Terminase-like family
ECDMHAGH_00681 1.8e-264 S Phage portal protein, SPP1 Gp6-like
ECDMHAGH_00682 1.3e-75 S Phage Mu protein F like protein
ECDMHAGH_00683 4.8e-42 S Domain of unknown function (DUF4355)
ECDMHAGH_00684 1.9e-179 gpG
ECDMHAGH_00686 4.1e-59
ECDMHAGH_00692 1.1e-119 L Probable transposase
ECDMHAGH_00695 1.5e-149 M Membrane
ECDMHAGH_00696 5.6e-60 M LysM domain
ECDMHAGH_00697 4.1e-16
ECDMHAGH_00698 5.1e-133
ECDMHAGH_00699 6.3e-43
ECDMHAGH_00701 1.5e-180 Z012_12235 S Baseplate J-like protein
ECDMHAGH_00703 1.4e-50 D nuclear chromosome segregation
ECDMHAGH_00704 2.5e-19
ECDMHAGH_00706 9.5e-42
ECDMHAGH_00707 6.1e-90 3.2.1.17 M hydrolase, family 25
ECDMHAGH_00709 5.4e-31
ECDMHAGH_00710 5e-113 soj D AAA domain
ECDMHAGH_00711 2.9e-248 L Transposase
ECDMHAGH_00712 9.7e-28 L Transposase
ECDMHAGH_00713 0.0 ydaO E amino acid
ECDMHAGH_00714 6.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ECDMHAGH_00715 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ECDMHAGH_00716 6.9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ECDMHAGH_00717 0.0 uup S ABC transporter, ATP-binding protein
ECDMHAGH_00718 7.5e-46 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
ECDMHAGH_00719 3e-215 yeaN P Transporter, major facilitator family protein
ECDMHAGH_00720 1.4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ECDMHAGH_00721 1.2e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
ECDMHAGH_00722 3.2e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
ECDMHAGH_00723 4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
ECDMHAGH_00724 2.6e-163 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ECDMHAGH_00725 1.7e-38 yabA L Involved in initiation control of chromosome replication
ECDMHAGH_00726 9.7e-178 holB 2.7.7.7 L DNA polymerase III
ECDMHAGH_00727 2.2e-54 yaaQ S Cyclic-di-AMP receptor
ECDMHAGH_00728 5.1e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECDMHAGH_00729 1.3e-38 yaaL S Protein of unknown function (DUF2508)
ECDMHAGH_00730 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ECDMHAGH_00731 1.6e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ECDMHAGH_00732 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ECDMHAGH_00733 1.6e-89 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ECDMHAGH_00734 6.8e-110 rsmC 2.1.1.172 J Methyltransferase
ECDMHAGH_00735 4.9e-37 nrdH O Glutaredoxin
ECDMHAGH_00736 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECDMHAGH_00737 1.6e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECDMHAGH_00738 2.2e-165 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
ECDMHAGH_00739 8.7e-107 yvdD 3.2.2.10 S Belongs to the LOG family
ECDMHAGH_00740 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ECDMHAGH_00741 7.1e-193 S membrane
ECDMHAGH_00742 1.6e-21 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatase
ECDMHAGH_00743 1.8e-117 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
ECDMHAGH_00744 1e-113 T PhoQ Sensor
ECDMHAGH_00745 2.9e-93 K Transcriptional regulatory protein, C terminal
ECDMHAGH_00746 4e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ECDMHAGH_00747 7.7e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ECDMHAGH_00748 1.2e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ECDMHAGH_00749 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ECDMHAGH_00750 1.1e-98 nusG K Participates in transcription elongation, termination and antitermination
ECDMHAGH_00751 4.3e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ECDMHAGH_00752 4.7e-97 sigH K Sigma-70 region 2
ECDMHAGH_00753 6.3e-91 yacP S YacP-like NYN domain
ECDMHAGH_00754 2.5e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECDMHAGH_00755 7.8e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ECDMHAGH_00756 7.4e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
ECDMHAGH_00757 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ECDMHAGH_00758 1.8e-212 yacL S domain protein
ECDMHAGH_00759 4.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ECDMHAGH_00760 3.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
ECDMHAGH_00761 2e-55
ECDMHAGH_00762 5.3e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ECDMHAGH_00764 5e-259 pepC 3.4.22.40 E Peptidase C1-like family
ECDMHAGH_00765 5.2e-226 V Beta-lactamase
ECDMHAGH_00766 1.6e-120 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ECDMHAGH_00767 3.4e-170 EG EamA-like transporter family
ECDMHAGH_00768 6.1e-166 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
ECDMHAGH_00769 4.6e-205 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ECDMHAGH_00770 2.8e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
ECDMHAGH_00771 1.5e-209 XK27_06930 V domain protein
ECDMHAGH_00772 2.7e-100 K Bacterial regulatory proteins, tetR family
ECDMHAGH_00773 1.4e-116 yliE T EAL domain
ECDMHAGH_00774 2e-163 2.7.7.65 T diguanylate cyclase
ECDMHAGH_00775 2.4e-176 K AI-2E family transporter
ECDMHAGH_00776 1.8e-153 manN G system, mannose fructose sorbose family IID component
ECDMHAGH_00777 9.6e-117 manM G PTS system
ECDMHAGH_00778 1.4e-60 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
ECDMHAGH_00779 4.3e-55 manL 2.7.1.191 G PTS system fructose IIA component
ECDMHAGH_00780 5.8e-109 gph 3.1.3.18 S HAD hydrolase, family IA, variant
ECDMHAGH_00781 2.6e-245 dinF V MatE
ECDMHAGH_00782 6.6e-75 K MarR family
ECDMHAGH_00783 2e-98 S Psort location CytoplasmicMembrane, score
ECDMHAGH_00784 4.8e-62 yobS K transcriptional regulator
ECDMHAGH_00785 7.4e-123 S Alpha/beta hydrolase family
ECDMHAGH_00786 2.5e-151 4.1.1.52 S Amidohydrolase
ECDMHAGH_00788 3.7e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ECDMHAGH_00789 2e-88 ydcK S Belongs to the SprT family
ECDMHAGH_00790 0.0 yhgF K Tex-like protein N-terminal domain protein
ECDMHAGH_00791 2.3e-72
ECDMHAGH_00792 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ECDMHAGH_00793 4.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ECDMHAGH_00794 2.9e-139 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
ECDMHAGH_00795 8.2e-93 MA20_25245 K FR47-like protein
ECDMHAGH_00796 1.9e-124 gntR1 K UbiC transcription regulator-associated domain protein
ECDMHAGH_00797 9.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECDMHAGH_00798 2.8e-135 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ECDMHAGH_00801 1.5e-149 yjjH S Calcineurin-like phosphoesterase
ECDMHAGH_00802 5.1e-298 dtpT U amino acid peptide transporter
ECDMHAGH_00803 9.9e-52 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
ECDMHAGH_00807 2.6e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECDMHAGH_00808 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ECDMHAGH_00809 1.2e-89 L PFAM Integrase, catalytic core
ECDMHAGH_00810 2.4e-109 citR K Putative sugar-binding domain
ECDMHAGH_00811 7.7e-82 ydjP I Alpha/beta hydrolase family
ECDMHAGH_00812 4.5e-311 ybiT S ABC transporter, ATP-binding protein
ECDMHAGH_00813 3.2e-158 K helix_turn_helix, arabinose operon control protein
ECDMHAGH_00814 4.3e-209 norA EGP Major facilitator Superfamily
ECDMHAGH_00815 2.7e-152 K LysR substrate binding domain
ECDMHAGH_00816 2.1e-159 MA20_14895 S Conserved hypothetical protein 698
ECDMHAGH_00817 1.1e-99 P Cadmium resistance transporter
ECDMHAGH_00818 2.1e-52 czrA K Transcriptional regulator, ArsR family
ECDMHAGH_00819 1e-308 mco Q Multicopper oxidase
ECDMHAGH_00820 2.1e-120 S SNARE associated Golgi protein
ECDMHAGH_00821 5e-310 cadA P P-type ATPase
ECDMHAGH_00822 1.7e-182 sdrF M Collagen binding domain
ECDMHAGH_00823 1.5e-68 S Iron-sulphur cluster biosynthesis
ECDMHAGH_00824 4.3e-59 gntR1 K Transcriptional regulator, GntR family
ECDMHAGH_00825 0.0 Q FtsX-like permease family
ECDMHAGH_00826 5.2e-136 cysA V ABC transporter, ATP-binding protein
ECDMHAGH_00827 7.2e-183 S Aldo keto reductase
ECDMHAGH_00828 6.7e-202 ytbD EGP Major facilitator Superfamily
ECDMHAGH_00829 1.8e-62 K Transcriptional regulator, HxlR family
ECDMHAGH_00830 6.2e-131
ECDMHAGH_00831 0.0 2.7.8.12 M glycerophosphotransferase
ECDMHAGH_00832 5.3e-72 K Transcriptional regulator
ECDMHAGH_00833 2.6e-152 1.6.5.2 GM NmrA-like family
ECDMHAGH_00834 1.9e-133 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ECDMHAGH_00835 2e-149 3.2.1.37 GH43 K helix_turn_helix, arabinose operon control protein
ECDMHAGH_00836 0.0 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
ECDMHAGH_00837 8.9e-226 G Major Facilitator
ECDMHAGH_00838 5.3e-122 IQ Enoyl-(Acyl carrier protein) reductase
ECDMHAGH_00839 2.7e-47 S membrane transporter protein
ECDMHAGH_00840 1.3e-35 S membrane transporter protein
ECDMHAGH_00841 6.9e-287 E dipeptidase activity
ECDMHAGH_00842 2.2e-142 K acetyltransferase
ECDMHAGH_00843 2e-143 iap CBM50 M NlpC/P60 family
ECDMHAGH_00844 2.7e-73 spx4 1.20.4.1 P ArsC family
ECDMHAGH_00845 7.2e-106 ypsA S Belongs to the UPF0398 family
ECDMHAGH_00846 6.4e-28 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ECDMHAGH_00848 6.1e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
ECDMHAGH_00849 9.9e-67 FG Scavenger mRNA decapping enzyme C-term binding
ECDMHAGH_00850 3.4e-247 amtB P ammonium transporter
ECDMHAGH_00851 4.8e-28
ECDMHAGH_00852 1.8e-82 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
ECDMHAGH_00853 8.8e-54
ECDMHAGH_00854 4.2e-121 S CAAX protease self-immunity
ECDMHAGH_00855 3.8e-85 K Bacterial regulatory proteins, tetR family
ECDMHAGH_00856 1.6e-111 XK27_02070 S Nitroreductase family
ECDMHAGH_00857 7.6e-208 yurR 1.4.5.1 E FAD dependent oxidoreductase
ECDMHAGH_00858 2.9e-64 rnhA 3.1.26.4 L Ribonuclease HI
ECDMHAGH_00859 8.6e-56 esbA S Family of unknown function (DUF5322)
ECDMHAGH_00860 3.4e-305 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
ECDMHAGH_00861 1.3e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ECDMHAGH_00862 2.1e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ECDMHAGH_00863 2.6e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ECDMHAGH_00864 1.7e-204 carA 6.3.5.5 F Belongs to the CarA family
ECDMHAGH_00865 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
ECDMHAGH_00866 0.0 FbpA K Fibronectin-binding protein
ECDMHAGH_00867 2.4e-69 K Transcriptional regulator
ECDMHAGH_00868 3.2e-197 npp S type I phosphodiesterase nucleotide pyrophosphatase
ECDMHAGH_00869 8.4e-232 yxiO S Vacuole effluxer Atg22 like
ECDMHAGH_00870 7.8e-160 degV S EDD domain protein, DegV family
ECDMHAGH_00871 3.2e-87 folT S ECF transporter, substrate-specific component
ECDMHAGH_00872 1.9e-74 gtcA S Teichoic acid glycosylation protein
ECDMHAGH_00873 2.6e-83 ysaA V VanZ like family
ECDMHAGH_00874 1.3e-90 V VanZ like family
ECDMHAGH_00875 2.5e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ECDMHAGH_00876 1.2e-143 mta K helix_turn_helix, mercury resistance
ECDMHAGH_00877 2.6e-169 C Zinc-binding dehydrogenase
ECDMHAGH_00878 6.9e-85 C Zinc-binding dehydrogenase
ECDMHAGH_00879 7e-13 K Bacterial regulatory proteins, tetR family
ECDMHAGH_00881 1.3e-67 IQ KR domain
ECDMHAGH_00882 1.4e-72 S membrane transporter protein
ECDMHAGH_00883 4.3e-47 S Phosphatidylethanolamine-binding protein
ECDMHAGH_00884 1.3e-35 yobS K transcriptional regulator
ECDMHAGH_00885 3.2e-119 Q Methyltransferase domain
ECDMHAGH_00886 2.1e-119 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ECDMHAGH_00887 2.1e-95 yneE K Transcriptional regulator
ECDMHAGH_00888 7.1e-13 yneE K Transcriptional regulator
ECDMHAGH_00890 9.1e-54 XK27_02470 K LytTr DNA-binding domain
ECDMHAGH_00891 1.7e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ECDMHAGH_00892 1.7e-168 whiA K May be required for sporulation
ECDMHAGH_00893 3.4e-191 ybhK S Required for morphogenesis under gluconeogenic growth conditions
ECDMHAGH_00894 4.8e-165 rapZ S Displays ATPase and GTPase activities
ECDMHAGH_00895 2.4e-90 S Short repeat of unknown function (DUF308)
ECDMHAGH_00896 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ECDMHAGH_00897 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ECDMHAGH_00898 4.5e-94 K acetyltransferase
ECDMHAGH_00899 6.7e-116 yfbR S HD containing hydrolase-like enzyme
ECDMHAGH_00901 9.9e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ECDMHAGH_00902 8.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ECDMHAGH_00903 1.5e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
ECDMHAGH_00904 1.1e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ECDMHAGH_00905 9.5e-172 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ECDMHAGH_00906 5.5e-30 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
ECDMHAGH_00907 1.7e-54 pspC KT PspC domain protein
ECDMHAGH_00908 1.2e-118 phoU P Plays a role in the regulation of phosphate uptake
ECDMHAGH_00909 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ECDMHAGH_00910 1.8e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ECDMHAGH_00911 1.3e-154 pstA P Phosphate transport system permease protein PstA
ECDMHAGH_00912 1e-157 pstC P probably responsible for the translocation of the substrate across the membrane
ECDMHAGH_00913 2.1e-160 pstS P Phosphate
ECDMHAGH_00914 3.1e-248 phoR 2.7.13.3 T Histidine kinase
ECDMHAGH_00915 7.6e-129 K response regulator
ECDMHAGH_00916 6.2e-221 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
ECDMHAGH_00917 5.6e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ECDMHAGH_00918 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ECDMHAGH_00919 7.9e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECDMHAGH_00920 2e-123 comFC S Competence protein
ECDMHAGH_00921 6.3e-254 comFA L Helicase C-terminal domain protein
ECDMHAGH_00922 4.4e-115 yvyE 3.4.13.9 S YigZ family
ECDMHAGH_00923 3.6e-178 tagO 2.7.8.33, 2.7.8.35 M transferase
ECDMHAGH_00924 1.6e-60 lrgA S LrgA family
ECDMHAGH_00925 3.7e-140 lrgB M LrgB-like family
ECDMHAGH_00926 6.2e-126 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ECDMHAGH_00927 1.7e-12
ECDMHAGH_00928 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ECDMHAGH_00929 7.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECDMHAGH_00930 3.7e-134 ybbR S YbbR-like protein
ECDMHAGH_00931 1.3e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ECDMHAGH_00932 2.9e-122 S Protein of unknown function (DUF1361)
ECDMHAGH_00933 0.0 yjcE P Sodium proton antiporter
ECDMHAGH_00934 5e-165 murB 1.3.1.98 M Cell wall formation
ECDMHAGH_00935 2.6e-151 xth 3.1.11.2 L exodeoxyribonuclease III
ECDMHAGH_00936 6e-102 dnaQ 2.7.7.7 L DNA polymerase III
ECDMHAGH_00937 9.7e-194 C Aldo keto reductase family protein
ECDMHAGH_00938 1.4e-87 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
ECDMHAGH_00939 1.9e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
ECDMHAGH_00940 4.6e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
ECDMHAGH_00941 8.8e-141 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ECDMHAGH_00942 4.9e-102 yxjI
ECDMHAGH_00943 6.4e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ECDMHAGH_00944 2.3e-81 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
ECDMHAGH_00945 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ECDMHAGH_00946 8.1e-137 est 3.1.1.1 S Serine aminopeptidase, S33
ECDMHAGH_00947 4.9e-32 secG U Preprotein translocase
ECDMHAGH_00948 2.2e-282 clcA P chloride
ECDMHAGH_00950 8e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ECDMHAGH_00951 8.7e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ECDMHAGH_00952 4.3e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
ECDMHAGH_00953 9e-192 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ECDMHAGH_00954 1.6e-183 cggR K Putative sugar-binding domain
ECDMHAGH_00956 1.4e-107 S ECF transporter, substrate-specific component
ECDMHAGH_00957 2.3e-61 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
ECDMHAGH_00958 3.8e-196 araR K Transcriptional regulator
ECDMHAGH_00959 6.5e-249 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
ECDMHAGH_00960 8.1e-304 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
ECDMHAGH_00961 3.2e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
ECDMHAGH_00962 5e-281 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
ECDMHAGH_00963 5.5e-90 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
ECDMHAGH_00966 1.4e-53 S Glycine cleavage H-protein
ECDMHAGH_00967 9.1e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
ECDMHAGH_00968 7.2e-141 yejC S Protein of unknown function (DUF1003)
ECDMHAGH_00969 6.3e-105 3.2.2.20 K acetyltransferase
ECDMHAGH_00970 1.4e-86 nimA S resistance protein
ECDMHAGH_00971 3e-90 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
ECDMHAGH_00972 1e-69
ECDMHAGH_00973 1.9e-217 EGP Major facilitator Superfamily
ECDMHAGH_00974 1.2e-233 pyrP F Permease
ECDMHAGH_00975 8.1e-49 azlD S Branched-chain amino acid transport protein (AzlD)
ECDMHAGH_00976 1.3e-107 azlC E branched-chain amino acid
ECDMHAGH_00977 1e-37 yyaN K MerR HTH family regulatory protein
ECDMHAGH_00978 2.8e-102 S Domain of unknown function (DUF4811)
ECDMHAGH_00979 4.3e-267 lmrB EGP Major facilitator Superfamily
ECDMHAGH_00980 1.8e-72 merR K MerR HTH family regulatory protein
ECDMHAGH_00981 1.3e-102 K Acetyltransferase (GNAT) domain
ECDMHAGH_00982 2e-158 czcD P cation diffusion facilitator family transporter
ECDMHAGH_00983 1.5e-120 sirR K iron dependent repressor
ECDMHAGH_00984 6.2e-121 thrE S Putative threonine/serine exporter
ECDMHAGH_00985 1.1e-72 S Threonine/Serine exporter, ThrE
ECDMHAGH_00986 9.4e-121 lssY 3.6.1.27 I phosphatase
ECDMHAGH_00987 3.3e-149 I alpha/beta hydrolase fold
ECDMHAGH_00988 8e-25 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECDMHAGH_00989 1.3e-274 lysP E amino acid
ECDMHAGH_00990 9.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
ECDMHAGH_00991 4.9e-211 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ECDMHAGH_00992 2.2e-131 ydfG S KR domain
ECDMHAGH_00994 3.3e-100
ECDMHAGH_00995 4.7e-156 map 3.4.11.18 E Methionine Aminopeptidase
ECDMHAGH_00996 6.6e-145 S Sucrose-6F-phosphate phosphohydrolase
ECDMHAGH_00997 2.6e-203 bcr1 EGP Major facilitator Superfamily
ECDMHAGH_00998 1.3e-126 S haloacid dehalogenase-like hydrolase
ECDMHAGH_00999 4.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
ECDMHAGH_01000 1.6e-174 3.5.2.6 V Beta-lactamase enzyme family
ECDMHAGH_01001 1.9e-62 yvoA_1 K Transcriptional regulator, GntR family
ECDMHAGH_01002 4.3e-124 skfE V ATPases associated with a variety of cellular activities
ECDMHAGH_01003 3.4e-119
ECDMHAGH_01004 2.2e-137 3.1.3.48 T Tyrosine phosphatase family
ECDMHAGH_01005 3.4e-121 S membrane transporter protein
ECDMHAGH_01006 9.5e-92 rmaB K Transcriptional regulator, MarR family
ECDMHAGH_01007 0.0 lmrA 3.6.3.44 V ABC transporter
ECDMHAGH_01008 2.4e-107 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ECDMHAGH_01009 3.6e-109 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
ECDMHAGH_01010 6e-55 S Domain of unknown function (DU1801)
ECDMHAGH_01011 0.0 epsA I PAP2 superfamily
ECDMHAGH_01012 4.6e-70 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
ECDMHAGH_01013 8.7e-159 K LysR substrate binding domain
ECDMHAGH_01014 8.5e-284 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
ECDMHAGH_01015 2.1e-97 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
ECDMHAGH_01016 6e-70
ECDMHAGH_01017 1.7e-157 P ABC-type cobalt transport system permease component CbiQ and related transporters
ECDMHAGH_01018 6.2e-307 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
ECDMHAGH_01019 1.4e-113 S ECF-type riboflavin transporter, S component
ECDMHAGH_01020 3.8e-177 U FFAT motif binding
ECDMHAGH_01021 1e-53 S Domain of unknown function (DUF4430)
ECDMHAGH_01022 8.2e-59 K helix_turn_helix, arabinose operon control protein
ECDMHAGH_01023 1.9e-40 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
ECDMHAGH_01024 2.4e-133 C Oxidoreductase
ECDMHAGH_01025 4.3e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ECDMHAGH_01026 1.8e-265 glnPH2 P ABC transporter permease
ECDMHAGH_01027 2.6e-132 yebC K Transcriptional regulatory protein
ECDMHAGH_01028 9.9e-172 comGA NU Type II IV secretion system protein
ECDMHAGH_01029 1.2e-166 comGB NU type II secretion system
ECDMHAGH_01030 1.1e-47 comGC U competence protein ComGC
ECDMHAGH_01031 2.5e-77
ECDMHAGH_01033 1.6e-73
ECDMHAGH_01034 2e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
ECDMHAGH_01035 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECDMHAGH_01036 6.1e-255 cycA E Amino acid permease
ECDMHAGH_01037 1.1e-153 yeaE S Aldo keto
ECDMHAGH_01038 5.3e-115 S Calcineurin-like phosphoesterase
ECDMHAGH_01039 1.5e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
ECDMHAGH_01040 2.9e-82 yutD S Protein of unknown function (DUF1027)
ECDMHAGH_01041 1.7e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ECDMHAGH_01042 7.7e-117 S Protein of unknown function (DUF1461)
ECDMHAGH_01043 6.9e-89 S WxL domain surface cell wall-binding
ECDMHAGH_01044 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
ECDMHAGH_01045 7.8e-242 M domain protein
ECDMHAGH_01046 2.4e-251 yfnA E Amino Acid
ECDMHAGH_01047 4.8e-140 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
ECDMHAGH_01048 4.5e-112 ytbE C Aldo keto reductase
ECDMHAGH_01049 6.1e-64 IQ Enoyl-(Acyl carrier protein) reductase
ECDMHAGH_01050 2.6e-13 K helix_turn_helix, mercury resistance
ECDMHAGH_01051 2.9e-122 dedA S SNARE-like domain protein
ECDMHAGH_01052 2.3e-87 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
ECDMHAGH_01053 7.8e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECDMHAGH_01054 5.2e-71 yugI 5.3.1.9 J general stress protein
ECDMHAGH_01055 7.4e-62 rplQ J Ribosomal protein L17
ECDMHAGH_01056 9.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ECDMHAGH_01057 7.5e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ECDMHAGH_01058 1.3e-60 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ECDMHAGH_01059 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ECDMHAGH_01060 3.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ECDMHAGH_01061 1.2e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ECDMHAGH_01062 1.9e-69 rplO J Binds to the 23S rRNA
ECDMHAGH_01063 3.8e-24 rpmD J Ribosomal protein L30
ECDMHAGH_01064 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ECDMHAGH_01065 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ECDMHAGH_01066 3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ECDMHAGH_01067 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ECDMHAGH_01068 2.1e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ECDMHAGH_01069 1.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ECDMHAGH_01070 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ECDMHAGH_01071 5.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ECDMHAGH_01072 4.8e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
ECDMHAGH_01073 7.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ECDMHAGH_01074 5.1e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ECDMHAGH_01075 2.4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ECDMHAGH_01076 1.8e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ECDMHAGH_01077 7.9e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ECDMHAGH_01078 2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ECDMHAGH_01079 3.2e-107 rplD J Forms part of the polypeptide exit tunnel
ECDMHAGH_01080 6.1e-117 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ECDMHAGH_01081 8.9e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
ECDMHAGH_01082 1.3e-230 mepA V MATE efflux family protein
ECDMHAGH_01083 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ECDMHAGH_01084 3.2e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ECDMHAGH_01085 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ECDMHAGH_01086 2e-112 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
ECDMHAGH_01087 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ECDMHAGH_01088 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ECDMHAGH_01089 1.6e-103 K Bacterial regulatory proteins, tetR family
ECDMHAGH_01090 2.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ECDMHAGH_01091 6.4e-207 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ECDMHAGH_01092 0.0 pacL 3.6.3.8 P P-type ATPase
ECDMHAGH_01093 1.2e-211 3.1.3.1 S associated with various cellular activities
ECDMHAGH_01094 3.3e-247 S Putative metallopeptidase domain
ECDMHAGH_01095 1.4e-47
ECDMHAGH_01096 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ECDMHAGH_01097 1.9e-40 ylqC S Belongs to the UPF0109 family
ECDMHAGH_01098 4.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ECDMHAGH_01099 4.5e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ECDMHAGH_01100 2.7e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ECDMHAGH_01101 4.3e-188 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ECDMHAGH_01102 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ECDMHAGH_01103 2.1e-79 marR K Transcriptional regulator
ECDMHAGH_01104 1.8e-181 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ECDMHAGH_01105 2e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECDMHAGH_01106 9.4e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
ECDMHAGH_01107 3.2e-122 IQ reductase
ECDMHAGH_01108 4.7e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ECDMHAGH_01109 6.7e-72 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ECDMHAGH_01110 6.7e-69 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
ECDMHAGH_01111 5.5e-264 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
ECDMHAGH_01112 1.2e-154 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ECDMHAGH_01113 6.5e-142 accA 2.1.3.15, 6.4.1.2 I alpha subunit
ECDMHAGH_01114 2.6e-119 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
ECDMHAGH_01115 2e-138 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ECDMHAGH_01116 2.2e-85 bioY S BioY family
ECDMHAGH_01117 4.4e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
ECDMHAGH_01118 1.8e-87 entB 3.5.1.19 Q Isochorismatase family
ECDMHAGH_01119 1e-108 S NAD(P)H-binding
ECDMHAGH_01120 1.9e-31 K helix_turn_helix, mercury resistance
ECDMHAGH_01121 3.2e-22 papX3 K Transcriptional regulator
ECDMHAGH_01122 2e-112 ydiC1 EGP Major facilitator Superfamily
ECDMHAGH_01123 3e-07 K MarR family
ECDMHAGH_01125 7.3e-104 T EAL domain
ECDMHAGH_01126 3.2e-89
ECDMHAGH_01127 3.1e-164 pgaC GT2 M Glycosyl transferase
ECDMHAGH_01128 3.5e-52 pgaC GT2 M Glycosyl transferase
ECDMHAGH_01130 3.1e-101 ytqB J Putative rRNA methylase
ECDMHAGH_01131 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ECDMHAGH_01132 1e-46
ECDMHAGH_01133 1.1e-121 P ABC-type multidrug transport system ATPase component
ECDMHAGH_01134 3.1e-144 S NADPH-dependent FMN reductase
ECDMHAGH_01135 4.4e-52
ECDMHAGH_01136 8.8e-298 ytgP S Polysaccharide biosynthesis protein
ECDMHAGH_01137 2.1e-82 rluB 5.4.99.19, 5.4.99.20, 5.4.99.21, 5.4.99.22 J pseudouridine synthase activity
ECDMHAGH_01138 2.9e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ECDMHAGH_01139 3.3e-269 pepV 3.5.1.18 E dipeptidase PepV
ECDMHAGH_01140 8.2e-85 uspA T Belongs to the universal stress protein A family
ECDMHAGH_01141 1.8e-201 ald 1.4.1.1 C Belongs to the AlaDH PNT family
ECDMHAGH_01142 1.1e-245 cycA E Amino acid permease
ECDMHAGH_01143 2e-55 ytzB S Small secreted protein
ECDMHAGH_01144 4e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ECDMHAGH_01145 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ECDMHAGH_01146 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
ECDMHAGH_01147 9.5e-258 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
ECDMHAGH_01148 6.9e-110 pnuC H nicotinamide mononucleotide transporter
ECDMHAGH_01149 4.6e-118 ybhL S Belongs to the BI1 family
ECDMHAGH_01150 3.3e-113 F Permease
ECDMHAGH_01151 4.4e-38 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_01152 1.9e-113 F Permease
ECDMHAGH_01153 7.9e-260 guaD 3.5.4.3 F Amidohydrolase family
ECDMHAGH_01154 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECDMHAGH_01155 3.3e-163 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ECDMHAGH_01156 5.4e-110 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ECDMHAGH_01157 7.8e-88 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ECDMHAGH_01158 1.4e-243 dnaB L replication initiation and membrane attachment
ECDMHAGH_01159 4.3e-164 dnaI L Primosomal protein DnaI
ECDMHAGH_01160 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ECDMHAGH_01161 4.4e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ECDMHAGH_01162 7.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
ECDMHAGH_01163 3.7e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ECDMHAGH_01164 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ECDMHAGH_01165 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ECDMHAGH_01166 5.9e-255 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ECDMHAGH_01167 4.2e-71 yabR J RNA binding
ECDMHAGH_01168 9.7e-44 divIC D Septum formation initiator
ECDMHAGH_01169 1.6e-39 yabO J S4 domain protein
ECDMHAGH_01170 9.1e-292 yabM S Polysaccharide biosynthesis protein
ECDMHAGH_01171 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ECDMHAGH_01172 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ECDMHAGH_01173 2.2e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ECDMHAGH_01174 7.1e-256 S Putative peptidoglycan binding domain
ECDMHAGH_01176 1.1e-113 S (CBS) domain
ECDMHAGH_01177 3.6e-61 ndoA L Toxic component of a toxin-antitoxin (TA) module
ECDMHAGH_01179 3.2e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECDMHAGH_01180 6.4e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ECDMHAGH_01181 8e-213 S nuclear-transcribed mRNA catabolic process, no-go decay
ECDMHAGH_01182 1.6e-240 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ECDMHAGH_01183 3.5e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ECDMHAGH_01184 1.8e-147
ECDMHAGH_01185 7.3e-145 htpX O Belongs to the peptidase M48B family
ECDMHAGH_01186 9.9e-95 lemA S LemA family
ECDMHAGH_01187 1.3e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ECDMHAGH_01188 3.1e-70 XK27_00720 S Leucine-rich repeat (LRR) protein
ECDMHAGH_01189 2.2e-136 XK27_00720 S Leucine-rich repeat (LRR) protein
ECDMHAGH_01190 7.4e-111 XK27_00720 S regulation of response to stimulus
ECDMHAGH_01191 2.8e-108 S Cell surface protein
ECDMHAGH_01192 3.7e-32 S WxL domain surface cell wall-binding
ECDMHAGH_01193 1.5e-17 S WxL domain surface cell wall-binding
ECDMHAGH_01195 2.5e-50 XK27_00720 S Leucine-rich repeat (LRR) protein
ECDMHAGH_01196 1.9e-39 XK27_00720 S regulation of response to stimulus
ECDMHAGH_01197 1.2e-11 S WxL domain surface cell wall-binding
ECDMHAGH_01198 9e-09 S WxL domain surface cell wall-binding
ECDMHAGH_01199 9.8e-18 S WxL domain surface cell wall-binding
ECDMHAGH_01200 8.7e-117 srtA 3.4.22.70 M sortase family
ECDMHAGH_01201 4.3e-42 rpmE2 J Ribosomal protein L31
ECDMHAGH_01202 8.9e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ECDMHAGH_01203 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
ECDMHAGH_01204 1.7e-128 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
ECDMHAGH_01205 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
ECDMHAGH_01206 1.3e-72 K Transcriptional regulator
ECDMHAGH_01207 4.5e-236
ECDMHAGH_01208 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
ECDMHAGH_01209 8.4e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ECDMHAGH_01210 5.8e-54 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ECDMHAGH_01211 4.9e-78 ywiB S Domain of unknown function (DUF1934)
ECDMHAGH_01212 9.2e-150 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
ECDMHAGH_01213 1.1e-264 ywfO S HD domain protein
ECDMHAGH_01214 1.3e-143 yxeH S hydrolase
ECDMHAGH_01215 0.0 xpkA 4.1.2.22, 4.1.2.9 G Phosphoketolase
ECDMHAGH_01216 7.5e-132 gntR K UbiC transcription regulator-associated domain protein
ECDMHAGH_01217 4.7e-70 racA K helix_turn_helix, mercury resistance
ECDMHAGH_01218 9.7e-56 S Domain of unknown function (DUF3899)
ECDMHAGH_01219 5.5e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ECDMHAGH_01220 2.5e-216 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ECDMHAGH_01221 1.5e-144 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
ECDMHAGH_01224 1.1e-131 znuB U ABC 3 transport family
ECDMHAGH_01225 2.7e-131 fhuC P ABC transporter
ECDMHAGH_01226 2.3e-170 znuA P Belongs to the bacterial solute-binding protein 9 family
ECDMHAGH_01227 3.3e-154 S Prolyl oligopeptidase family
ECDMHAGH_01228 1.3e-86 KTV abc transporter atp-binding protein
ECDMHAGH_01229 5.1e-87 V ABC transporter
ECDMHAGH_01230 2.2e-54 V Transport permease protein
ECDMHAGH_01232 1e-87
ECDMHAGH_01233 7.7e-166 2.7.1.2 GK ROK family
ECDMHAGH_01234 1e-292 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ECDMHAGH_01236 4.2e-209 xylR GK ROK family
ECDMHAGH_01237 1.2e-258 xylP G MFS/sugar transport protein
ECDMHAGH_01238 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
ECDMHAGH_01239 3.1e-140 E Bacterial extracellular solute-binding proteins, family 5 Middle
ECDMHAGH_01240 1.1e-113 K Bacterial regulatory proteins, tetR family
ECDMHAGH_01241 1.6e-230 XK27_06930 S ABC-2 family transporter protein
ECDMHAGH_01242 9.9e-64 rmeB K transcriptional regulator, MerR family
ECDMHAGH_01243 1e-47 ydcZ S Putative inner membrane exporter, YdcZ
ECDMHAGH_01244 4.5e-44 ydcZ S Putative inner membrane exporter, YdcZ
ECDMHAGH_01245 3.1e-129 qmcA O prohibitin homologues
ECDMHAGH_01246 5.7e-55 S protein encoded in hypervariable junctions of pilus gene clusters
ECDMHAGH_01247 6.2e-134
ECDMHAGH_01248 4.5e-100 GBS0088 S Nucleotidyltransferase
ECDMHAGH_01249 1.8e-84 yybC S Protein of unknown function (DUF2798)
ECDMHAGH_01250 2.6e-56 ydiI Q Thioesterase superfamily
ECDMHAGH_01251 1.1e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ECDMHAGH_01252 5.1e-265 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
ECDMHAGH_01253 5.5e-95 S Protein of unknown function (DUF1097)
ECDMHAGH_01254 4.6e-166
ECDMHAGH_01255 1.4e-286 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECDMHAGH_01256 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
ECDMHAGH_01257 5.9e-40 lmrP E Major Facilitator Superfamily
ECDMHAGH_01258 1.3e-157 lmrP E Major Facilitator Superfamily
ECDMHAGH_01261 3.7e-73 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ECDMHAGH_01262 6.6e-11 yobS K transcriptional regulator
ECDMHAGH_01263 2.2e-55 ywnB S NAD(P)H-binding
ECDMHAGH_01264 8.9e-107 dhaS K Bacterial regulatory proteins, tetR family
ECDMHAGH_01265 1.7e-279 E amino acid
ECDMHAGH_01266 6.5e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
ECDMHAGH_01267 1.4e-294 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ECDMHAGH_01269 8.4e-173
ECDMHAGH_01270 8.4e-67 EGP Major facilitator Superfamily
ECDMHAGH_01271 9.5e-250 gshR 1.8.1.7 C Glutathione reductase
ECDMHAGH_01272 9.1e-36 ygbF S Sugar efflux transporter for intercellular exchange
ECDMHAGH_01274 3.7e-197 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ECDMHAGH_01275 1e-35
ECDMHAGH_01276 4.7e-137 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
ECDMHAGH_01277 8.2e-233 gntT EG Citrate transporter
ECDMHAGH_01278 1.2e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
ECDMHAGH_01279 9.4e-107 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase HUMPS family
ECDMHAGH_01280 3.2e-87 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M sugar phosphate isomerase involved in capsule formation
ECDMHAGH_01281 5.2e-176 kdgR K helix_turn _helix lactose operon repressor
ECDMHAGH_01282 4.3e-55
ECDMHAGH_01283 1.8e-83
ECDMHAGH_01284 0.0 helD 3.6.4.12 L DNA helicase
ECDMHAGH_01285 1.2e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
ECDMHAGH_01286 4.8e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ECDMHAGH_01287 2.9e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
ECDMHAGH_01288 6e-177
ECDMHAGH_01289 6.8e-130 cobB K SIR2 family
ECDMHAGH_01290 3.8e-51
ECDMHAGH_01291 4.4e-160 yunF F Protein of unknown function DUF72
ECDMHAGH_01292 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECDMHAGH_01293 1.8e-147 tatD L hydrolase, TatD family
ECDMHAGH_01294 1.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ECDMHAGH_01295 8.5e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ECDMHAGH_01296 4.3e-36 veg S Biofilm formation stimulator VEG
ECDMHAGH_01297 1.9e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ECDMHAGH_01298 1e-107 ung2 3.2.2.27 L Uracil-DNA glycosylase
ECDMHAGH_01299 2.8e-120 K response regulator
ECDMHAGH_01300 9.3e-292 arlS 2.7.13.3 T Histidine kinase
ECDMHAGH_01301 1.2e-70 S Protein of unknown function (DUF1093)
ECDMHAGH_01302 1.5e-134 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ECDMHAGH_01303 2.7e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
ECDMHAGH_01304 1.6e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECDMHAGH_01305 4e-92 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
ECDMHAGH_01306 1.7e-66 yodB K Transcriptional regulator, HxlR family
ECDMHAGH_01307 1.7e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ECDMHAGH_01308 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ECDMHAGH_01309 3.8e-207 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ECDMHAGH_01310 1e-119 udk 2.7.1.48 F Cytidine monophosphokinase
ECDMHAGH_01311 6.3e-71 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ECDMHAGH_01312 1.7e-56 yneR S Belongs to the HesB IscA family
ECDMHAGH_01313 0.0 S membrane
ECDMHAGH_01314 4.2e-27 CP_0775 S Domain of unknown function (DUF378)
ECDMHAGH_01315 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
ECDMHAGH_01316 2.5e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ECDMHAGH_01317 1.3e-91 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ECDMHAGH_01318 9.9e-118 gluP 3.4.21.105 S Peptidase, S54 family
ECDMHAGH_01319 9.3e-36 yqgQ S Bacterial protein of unknown function (DUF910)
ECDMHAGH_01320 1.2e-180 glk 2.7.1.2 G Glucokinase
ECDMHAGH_01321 2.1e-70 yqhL P Rhodanese-like protein
ECDMHAGH_01322 3.1e-23 WQ51_02665 S Protein of unknown function (DUF3042)
ECDMHAGH_01323 7e-141 glpQ 3.1.4.46 C phosphodiesterase
ECDMHAGH_01324 2e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ECDMHAGH_01325 2.1e-64 glnR K Transcriptional regulator
ECDMHAGH_01326 4.9e-262 glnA 6.3.1.2 E glutamine synthetase
ECDMHAGH_01328 3.2e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ECDMHAGH_01329 2.4e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ECDMHAGH_01330 4.6e-241 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ECDMHAGH_01331 6.4e-40 GM NmrA-like family
ECDMHAGH_01332 4.3e-232 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
ECDMHAGH_01333 1e-122 GM NmrA-like family
ECDMHAGH_01334 4.3e-98 fadR K Bacterial regulatory proteins, tetR family
ECDMHAGH_01335 4.3e-180 D Alpha beta
ECDMHAGH_01336 2.5e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
ECDMHAGH_01337 1.8e-164 I Alpha beta
ECDMHAGH_01338 0.0 O Pro-kumamolisin, activation domain
ECDMHAGH_01339 2.9e-119 S Membrane
ECDMHAGH_01340 1.8e-133 puuD S peptidase C26
ECDMHAGH_01341 1.6e-36
ECDMHAGH_01342 2.2e-111 magIII L Base excision DNA repair protein, HhH-GPD family
ECDMHAGH_01343 7.2e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ECDMHAGH_01344 4.5e-199 M NlpC/P60 family
ECDMHAGH_01345 6.4e-162 G Peptidase_C39 like family
ECDMHAGH_01346 1.4e-242 3.2.1.21 GH3 G Fibronectin type III-like domain
ECDMHAGH_01347 5.2e-79 K AraC-like ligand binding domain
ECDMHAGH_01348 1.7e-247 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
ECDMHAGH_01349 2e-71 blt G MFS/sugar transport protein
ECDMHAGH_01352 2.3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
ECDMHAGH_01353 2.8e-290 xylB 2.7.1.12, 2.7.1.16, 2.7.1.17 G Xylulose kinase
ECDMHAGH_01354 1.1e-217 xylT EGP Major facilitator Superfamily
ECDMHAGH_01355 3.3e-141 IQ reductase
ECDMHAGH_01356 1e-68 frataxin S Domain of unknown function (DU1801)
ECDMHAGH_01357 0.0 S membrane
ECDMHAGH_01358 1.1e-89 uspA T universal stress protein
ECDMHAGH_01359 4.7e-96 yxkA S Phosphatidylethanolamine-binding protein
ECDMHAGH_01360 1.8e-220 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ECDMHAGH_01361 3.3e-122 kcsA P Ion channel
ECDMHAGH_01362 1.4e-49
ECDMHAGH_01363 1.6e-171 C Aldo keto reductase
ECDMHAGH_01364 7.5e-70
ECDMHAGH_01365 7e-95 Z012_06855 S Acetyltransferase (GNAT) family
ECDMHAGH_01366 3.2e-251 nhaC C Na H antiporter NhaC
ECDMHAGH_01367 3.1e-190 S Membrane transport protein
ECDMHAGH_01368 7e-189 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECDMHAGH_01369 1.4e-268 yufL 2.7.13.3 T Single cache domain 3
ECDMHAGH_01370 3e-125 malR3 K cheY-homologous receiver domain
ECDMHAGH_01371 2.7e-175 S ABC-2 family transporter protein
ECDMHAGH_01372 1.2e-101 XK27_06935 K Bacterial regulatory proteins, tetR family
ECDMHAGH_01373 4e-124 yliE T Putative diguanylate phosphodiesterase
ECDMHAGH_01374 4.3e-153 E Bacterial extracellular solute-binding proteins, family 5 Middle
ECDMHAGH_01375 2.7e-75 gtrA S GtrA-like protein
ECDMHAGH_01376 6.5e-75 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
ECDMHAGH_01377 7.1e-85 cadD P Cadmium resistance transporter
ECDMHAGH_01379 5e-97 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
ECDMHAGH_01380 7.1e-175 draG 3.2.2.24 O ADP-ribosylglycohydrolase
ECDMHAGH_01381 4.3e-143 nlhH I Esterase
ECDMHAGH_01382 1.3e-35 mgrA K helix_turn_helix multiple antibiotic resistance protein
ECDMHAGH_01383 5.1e-81 argO S LysE type translocator
ECDMHAGH_01384 6.1e-173 yfjF U Sugar (and other) transporter
ECDMHAGH_01385 1.1e-59 K Bacterial regulatory proteins, tetR family
ECDMHAGH_01386 4.7e-120 lsa S ABC transporter
ECDMHAGH_01387 8.6e-36 S Domain of unknown function (DUF4440)
ECDMHAGH_01388 4e-113 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
ECDMHAGH_01389 3.3e-85 GM NAD(P)H-binding
ECDMHAGH_01390 2.5e-218 EGP Major Facilitator Superfamily
ECDMHAGH_01391 5.8e-143 ydhO 3.4.14.13 M NlpC/P60 family
ECDMHAGH_01392 3.3e-22 S Mor transcription activator family
ECDMHAGH_01393 2.3e-08 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
ECDMHAGH_01394 1.3e-107 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ECDMHAGH_01395 4.2e-166
ECDMHAGH_01396 5e-47 K Acetyltransferase (GNAT) domain
ECDMHAGH_01397 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
ECDMHAGH_01399 3.2e-37
ECDMHAGH_01400 4.5e-173 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ECDMHAGH_01401 0.0 smc D Required for chromosome condensation and partitioning
ECDMHAGH_01402 2.8e-128 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ECDMHAGH_01403 6.4e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECDMHAGH_01404 1.4e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ECDMHAGH_01405 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ECDMHAGH_01406 2.4e-311 yloV S DAK2 domain fusion protein YloV
ECDMHAGH_01407 5.2e-57 asp S Asp23 family, cell envelope-related function
ECDMHAGH_01408 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
ECDMHAGH_01409 2e-126 thiN 2.7.6.2 H thiamine pyrophosphokinase
ECDMHAGH_01410 7.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
ECDMHAGH_01411 3.6e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ECDMHAGH_01412 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
ECDMHAGH_01413 9.4e-130 stp 3.1.3.16 T phosphatase
ECDMHAGH_01414 2.8e-225 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ECDMHAGH_01415 4.3e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ECDMHAGH_01416 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ECDMHAGH_01417 1.8e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ECDMHAGH_01418 4.9e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ECDMHAGH_01419 3.3e-104 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
ECDMHAGH_01420 1e-51
ECDMHAGH_01421 1.8e-110 yktB S Belongs to the UPF0637 family
ECDMHAGH_01422 7.1e-80 yueI S Protein of unknown function (DUF1694)
ECDMHAGH_01423 1.7e-235 rarA L recombination factor protein RarA
ECDMHAGH_01424 3.2e-41
ECDMHAGH_01425 1e-81 usp6 T universal stress protein
ECDMHAGH_01426 1.4e-159 2.3.1.19 K Helix-turn-helix XRE-family like proteins
ECDMHAGH_01427 4.8e-301 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
ECDMHAGH_01428 2e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ECDMHAGH_01429 3.9e-176 S Protein of unknown function (DUF2785)
ECDMHAGH_01430 1.3e-140 f42a O Band 7 protein
ECDMHAGH_01431 1.9e-49 gcsH2 E glycine cleavage
ECDMHAGH_01432 1.1e-220 rodA D Belongs to the SEDS family
ECDMHAGH_01433 1.1e-33 S Protein of unknown function (DUF2969)
ECDMHAGH_01434 1.1e-52 yidD S Could be involved in insertion of integral membrane proteins into the membrane
ECDMHAGH_01435 1.1e-178 mbl D Cell shape determining protein MreB Mrl
ECDMHAGH_01436 1.3e-243 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ECDMHAGH_01437 4.3e-33 ywzB S Protein of unknown function (DUF1146)
ECDMHAGH_01438 8.3e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ECDMHAGH_01439 5.3e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ECDMHAGH_01440 7.3e-161 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ECDMHAGH_01441 5.1e-287 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ECDMHAGH_01442 1.3e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ECDMHAGH_01443 3.4e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ECDMHAGH_01444 7.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ECDMHAGH_01445 6.1e-126 atpB C it plays a direct role in the translocation of protons across the membrane
ECDMHAGH_01446 1.5e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ECDMHAGH_01447 1.2e-226 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ECDMHAGH_01448 1.2e-47 S NADPH-dependent FMN reductase
ECDMHAGH_01449 4.5e-71 S Protein of unknown function (DUF3021)
ECDMHAGH_01450 1.7e-70 K LytTr DNA-binding domain
ECDMHAGH_01451 6.9e-43 merR K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ECDMHAGH_01452 1.1e-155 lmrB EGP Major facilitator Superfamily
ECDMHAGH_01453 5.8e-41 N PFAM Uncharacterised protein family UPF0150
ECDMHAGH_01454 2.1e-207 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
ECDMHAGH_01455 6.8e-143 K LysR substrate binding domain
ECDMHAGH_01456 4e-30 adhR K MerR, DNA binding
ECDMHAGH_01457 8.2e-185 C Aldo/keto reductase family
ECDMHAGH_01458 4.1e-89 pnb C nitroreductase
ECDMHAGH_01459 7.7e-56 K GNAT family
ECDMHAGH_01460 1.8e-294 katA 1.11.1.6 C Belongs to the catalase family
ECDMHAGH_01461 3.9e-101 rimL J Acetyltransferase (GNAT) domain
ECDMHAGH_01462 1.7e-67
ECDMHAGH_01463 8.6e-67 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
ECDMHAGH_01464 7e-35 K Bacterial regulatory proteins, tetR family
ECDMHAGH_01465 7.9e-146 K Helix-turn-helix
ECDMHAGH_01466 2.7e-277 yjeM E Amino Acid
ECDMHAGH_01467 1.5e-272 pipD E Dipeptidase
ECDMHAGH_01468 4.5e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ECDMHAGH_01469 1.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
ECDMHAGH_01470 4.9e-295 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ECDMHAGH_01471 4.4e-50 S Protein of unknown function (DUF2975)
ECDMHAGH_01472 1.8e-27 yozG K Transcriptional regulator
ECDMHAGH_01473 1.5e-08 zntR K helix_turn_helix, mercury resistance
ECDMHAGH_01474 1.3e-218
ECDMHAGH_01475 2.6e-09 K MarR family
ECDMHAGH_01476 4.5e-100 yobS K Bacterial regulatory proteins, tetR family
ECDMHAGH_01477 2.9e-75 K helix_turn_helix, mercury resistance
ECDMHAGH_01478 1.6e-78 yphH S Cupin domain
ECDMHAGH_01479 3.6e-54 yphJ 4.1.1.44 S decarboxylase
ECDMHAGH_01480 1.5e-203 G Glycosyl hydrolases family 8
ECDMHAGH_01481 2.9e-168 XK27_00880 3.5.1.28 M hydrolase, family 25
ECDMHAGH_01482 6.8e-146 S Zinc-dependent metalloprotease
ECDMHAGH_01483 5.5e-106 tag 3.2.2.20 L glycosylase
ECDMHAGH_01484 6.5e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ECDMHAGH_01485 9.9e-306 sbcC L Putative exonuclease SbcCD, C subunit
ECDMHAGH_01486 3.4e-188 pva1 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
ECDMHAGH_01487 0.0 3.2.1.21 GH3 G hydrolase, family 3
ECDMHAGH_01489 0.0 E ABC transporter, substratebinding protein
ECDMHAGH_01490 5.9e-97 tag 3.2.2.20 L glycosylase
ECDMHAGH_01491 1.7e-145 P Belongs to the nlpA lipoprotein family
ECDMHAGH_01492 6.5e-193 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ECDMHAGH_01493 1.1e-113 metI P ABC transporter permease
ECDMHAGH_01494 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ECDMHAGH_01495 7e-214 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
ECDMHAGH_01496 2.8e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
ECDMHAGH_01497 4.6e-204 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ECDMHAGH_01498 9.8e-269 lpdA 1.8.1.4 C Dehydrogenase
ECDMHAGH_01499 3e-162 1.1.1.27 C L-malate dehydrogenase activity
ECDMHAGH_01500 7.9e-45 yktA S Belongs to the UPF0223 family
ECDMHAGH_01501 1.8e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
ECDMHAGH_01502 0.0 typA T GTP-binding protein TypA
ECDMHAGH_01503 2.4e-209 ftsW D Belongs to the SEDS family
ECDMHAGH_01504 1.3e-42 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
ECDMHAGH_01505 1.4e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
ECDMHAGH_01506 2.1e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ECDMHAGH_01507 8.1e-196 ylbL T Belongs to the peptidase S16 family
ECDMHAGH_01508 2.7e-107 comEA L Competence protein ComEA
ECDMHAGH_01509 1.2e-88 comEB 3.5.4.12 F ComE operon protein 2
ECDMHAGH_01510 0.0 comEC S Competence protein ComEC
ECDMHAGH_01511 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
ECDMHAGH_01512 2.1e-38 K transcriptional regulator
ECDMHAGH_01513 3.9e-94
ECDMHAGH_01514 2.1e-33 rpsT J Binds directly to 16S ribosomal RNA
ECDMHAGH_01515 1.3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ECDMHAGH_01516 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ECDMHAGH_01517 4e-162 S Tetratricopeptide repeat
ECDMHAGH_01518 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ECDMHAGH_01519 8.3e-222 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ECDMHAGH_01520 6.9e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ECDMHAGH_01521 6.6e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
ECDMHAGH_01522 3.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
ECDMHAGH_01523 3.3e-15
ECDMHAGH_01524 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ECDMHAGH_01525 3.3e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ECDMHAGH_01526 6.2e-105
ECDMHAGH_01527 3.8e-28
ECDMHAGH_01528 5.7e-180 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ECDMHAGH_01529 2.6e-54 yrvD S Pfam:DUF1049
ECDMHAGH_01530 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
ECDMHAGH_01531 3.2e-92 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ECDMHAGH_01532 1.1e-77 T Universal stress protein family
ECDMHAGH_01534 1.3e-74
ECDMHAGH_01535 4.5e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
ECDMHAGH_01536 1.7e-69 S MTH538 TIR-like domain (DUF1863)
ECDMHAGH_01539 1.7e-61
ECDMHAGH_01542 1e-81 ndk 2.7.4.6 F Belongs to the NDK family
ECDMHAGH_01543 7.7e-25 KT PspC domain
ECDMHAGH_01544 1.5e-123 G phosphoglycerate mutase
ECDMHAGH_01545 2.4e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
ECDMHAGH_01546 1.1e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
ECDMHAGH_01547 7.8e-79
ECDMHAGH_01548 9.3e-77 F nucleoside 2-deoxyribosyltransferase
ECDMHAGH_01549 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECDMHAGH_01550 1.8e-37 ynzC S UPF0291 protein
ECDMHAGH_01551 1.6e-32 yneF S Uncharacterised protein family (UPF0154)
ECDMHAGH_01552 1.2e-287 mdlA V ABC transporter
ECDMHAGH_01553 0.0 mdlB V ABC transporter
ECDMHAGH_01554 7.6e-120 plsC 2.3.1.51 I Acyltransferase
ECDMHAGH_01555 2.6e-135 yabB 2.1.1.223 L Methyltransferase small domain
ECDMHAGH_01556 6.4e-44 yazA L GIY-YIG catalytic domain protein
ECDMHAGH_01557 9.8e-183 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECDMHAGH_01558 6.5e-136 S Haloacid dehalogenase-like hydrolase
ECDMHAGH_01559 1.9e-144 rpsB J Belongs to the universal ribosomal protein uS2 family
ECDMHAGH_01560 1.9e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ECDMHAGH_01561 1.7e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ECDMHAGH_01562 6.9e-85 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ECDMHAGH_01563 3.2e-74
ECDMHAGH_01564 2.6e-146 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ECDMHAGH_01565 4.2e-136 cdsA 2.7.7.41 I Belongs to the CDS family
ECDMHAGH_01566 5.6e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
ECDMHAGH_01567 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ECDMHAGH_01568 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ECDMHAGH_01569 1.4e-38
ECDMHAGH_01570 1.8e-81 rimP J Required for maturation of 30S ribosomal subunits
ECDMHAGH_01571 1.5e-190 nusA K Participates in both transcription termination and antitermination
ECDMHAGH_01572 8.8e-47 ylxR K Protein of unknown function (DUF448)
ECDMHAGH_01573 1.4e-44 ylxQ J ribosomal protein
ECDMHAGH_01574 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ECDMHAGH_01575 9.4e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ECDMHAGH_01576 9.6e-169 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ECDMHAGH_01577 1.2e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
ECDMHAGH_01578 7.8e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ECDMHAGH_01579 5.2e-83 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ECDMHAGH_01580 0.0 dnaK O Heat shock 70 kDa protein
ECDMHAGH_01581 4.9e-178 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ECDMHAGH_01582 1.7e-37 L Transposase DDE domain
ECDMHAGH_01583 3.1e-68 L Transposase DDE domain
ECDMHAGH_01584 0.0 pepF E oligoendopeptidase F
ECDMHAGH_01585 1.6e-186 coiA 3.6.4.12 S Competence protein
ECDMHAGH_01586 3.9e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ECDMHAGH_01587 1.9e-149 ytmP 2.7.1.89 M Choline/ethanolamine kinase
ECDMHAGH_01588 5.2e-218 ecsB U ABC transporter
ECDMHAGH_01589 4.8e-134 ecsA V ABC transporter, ATP-binding protein
ECDMHAGH_01590 6.9e-83 hit FG histidine triad
ECDMHAGH_01591 1.7e-48
ECDMHAGH_01592 9.1e-151 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ECDMHAGH_01593 6e-185 S Metal dependent phosphohydrolases with conserved 'HD' motif.
ECDMHAGH_01594 0.0 L AAA domain
ECDMHAGH_01595 3e-226 yhaO L Ser Thr phosphatase family protein
ECDMHAGH_01596 1.8e-51 yheA S Belongs to the UPF0342 family
ECDMHAGH_01597 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ECDMHAGH_01598 4.7e-79 argR K Regulates arginine biosynthesis genes
ECDMHAGH_01599 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ECDMHAGH_01601 1.1e-17
ECDMHAGH_01602 2.5e-231 3.2.1.96, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ECDMHAGH_01603 1.4e-150 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ECDMHAGH_01604 2.4e-161 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ECDMHAGH_01605 6.1e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ECDMHAGH_01606 4.6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ECDMHAGH_01607 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ECDMHAGH_01608 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
ECDMHAGH_01609 4.1e-194 manA 5.3.1.8 G mannose-6-phosphate isomerase
ECDMHAGH_01610 1.2e-239 ktrB P Potassium uptake protein
ECDMHAGH_01611 1.8e-116 ktrA P domain protein
ECDMHAGH_01612 1.5e-197 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECDMHAGH_01613 1.1e-104 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
ECDMHAGH_01614 7.1e-220 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
ECDMHAGH_01615 1.3e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
ECDMHAGH_01616 1e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
ECDMHAGH_01617 8.8e-254 yfnA E Amino Acid
ECDMHAGH_01618 2.9e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
ECDMHAGH_01619 2.3e-158 brpA K Cell envelope-like function transcriptional attenuator common domain protein
ECDMHAGH_01620 3.5e-90 epsB M biosynthesis protein
ECDMHAGH_01621 5.3e-128 ywqD 2.7.10.1 D Capsular exopolysaccharide family
ECDMHAGH_01622 1.7e-137 ywqE 3.1.3.48 GM PHP domain protein
ECDMHAGH_01624 1.5e-58 rfbP 2.7.8.6 M Bacterial sugar transferase
ECDMHAGH_01625 6e-87 cps1D M Domain of unknown function (DUF4422)
ECDMHAGH_01626 0.0 xpkA 4.1.2.22, 4.1.2.9 G XFP C-terminal domain
ECDMHAGH_01627 9.3e-133
ECDMHAGH_01628 1.6e-183 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_01629 2.1e-39
ECDMHAGH_01630 2e-88 3.2.1.17 M hydrolase, family 25
ECDMHAGH_01632 3.5e-68 L Transposase
ECDMHAGH_01634 2.7e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
ECDMHAGH_01635 9.8e-40
ECDMHAGH_01636 1.6e-26
ECDMHAGH_01637 0.0 traA L MobA MobL family protein
ECDMHAGH_01638 3.6e-51
ECDMHAGH_01640 2e-101 tnpR L Resolvase, N terminal domain
ECDMHAGH_01641 1.8e-248 G MFS/sugar transport protein
ECDMHAGH_01642 1.8e-80 tnp L DDE domain
ECDMHAGH_01643 4.5e-263 npr 1.11.1.1 C NADH oxidase
ECDMHAGH_01644 2.1e-15 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_01645 4.2e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ECDMHAGH_01646 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
ECDMHAGH_01647 5e-60 P Rhodanese Homology Domain
ECDMHAGH_01648 6e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
ECDMHAGH_01649 1.2e-123 dnaD L Replication initiation and membrane attachment
ECDMHAGH_01650 2.1e-208 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
ECDMHAGH_01651 2.6e-83 ypmB S Protein conserved in bacteria
ECDMHAGH_01652 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
ECDMHAGH_01653 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
ECDMHAGH_01654 2.9e-171 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
ECDMHAGH_01655 2.4e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
ECDMHAGH_01656 8.1e-188 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ECDMHAGH_01657 2.3e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
ECDMHAGH_01658 3.3e-152 yitU 3.1.3.104 S hydrolase
ECDMHAGH_01659 7.3e-214 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ECDMHAGH_01660 8.6e-81
ECDMHAGH_01661 4.3e-46 S Oxidoreductase, aldo keto reductase family protein
ECDMHAGH_01662 1.9e-114 S Phage plasmid primase, P4
ECDMHAGH_01663 1.1e-81 L DNA replication protein
ECDMHAGH_01664 2.5e-07 L DNA replication protein
ECDMHAGH_01666 9.8e-41 L the current gene model (or a revised gene model) may contain a frame shift
ECDMHAGH_01669 5.3e-204 sip L Belongs to the 'phage' integrase family
ECDMHAGH_01672 3.8e-99 S Protein of unknown function (DUF1211)
ECDMHAGH_01673 1.5e-80 tspO T TspO/MBR family
ECDMHAGH_01674 0.0 S Bacterial membrane protein YfhO
ECDMHAGH_01675 7.1e-261 pgi 5.3.1.9 G Belongs to the GPI family
ECDMHAGH_01676 2.9e-154 glcU U sugar transport
ECDMHAGH_01677 2.4e-209 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
ECDMHAGH_01678 2.8e-266 T PhoQ Sensor
ECDMHAGH_01679 9e-147 K response regulator
ECDMHAGH_01681 2.4e-96 gepA S Protein of unknown function (DUF4065)
ECDMHAGH_01682 6.1e-33 S Motility quorum-sensing regulator, toxin of MqsA
ECDMHAGH_01683 7.9e-20 S transferase activity, transferring acyl groups
ECDMHAGH_01687 5.6e-23
ECDMHAGH_01688 6.8e-13
ECDMHAGH_01689 6.4e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ECDMHAGH_01690 4.5e-100 ahpC 1.11.1.15 O Peroxiredoxin
ECDMHAGH_01691 7.2e-56
ECDMHAGH_01692 2.3e-108 ylbE GM NAD(P)H-binding
ECDMHAGH_01693 3.7e-44
ECDMHAGH_01695 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ECDMHAGH_01696 1.7e-70 K Transcriptional regulator
ECDMHAGH_01697 2.3e-75 elaA S Gnat family
ECDMHAGH_01698 7.3e-45
ECDMHAGH_01699 2.3e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ECDMHAGH_01700 7.1e-155 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
ECDMHAGH_01701 7.4e-66 K Bacterial regulatory proteins, tetR family
ECDMHAGH_01702 3.4e-205 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
ECDMHAGH_01703 3.2e-158 1.1.1.65 C Aldo keto reductase
ECDMHAGH_01704 3.4e-94 wecD K Acetyltransferase (GNAT) family
ECDMHAGH_01705 8e-141 S zinc-ribbon domain
ECDMHAGH_01706 2.4e-222 S response to antibiotic
ECDMHAGH_01708 1.7e-84 F NUDIX domain
ECDMHAGH_01710 3.2e-103 padC Q Phenolic acid decarboxylase
ECDMHAGH_01711 2.2e-82 padR K Virulence activator alpha C-term
ECDMHAGH_01712 4.5e-100 K Bacterial regulatory proteins, tetR family
ECDMHAGH_01713 8.3e-185 1.1.1.219 GM Male sterility protein
ECDMHAGH_01714 1e-75 elaA S Gnat family
ECDMHAGH_01715 2.1e-79 yybA 2.3.1.57 K Transcriptional regulator
ECDMHAGH_01717 2.3e-72
ECDMHAGH_01718 1.1e-90
ECDMHAGH_01719 8e-89 P Cadmium resistance transporter
ECDMHAGH_01720 9.4e-118 sirR K Helix-turn-helix diphteria tox regulatory element
ECDMHAGH_01721 1.5e-71 T Universal stress protein family
ECDMHAGH_01722 1.5e-251 mntH P H( )-stimulated, divalent metal cation uptake system
ECDMHAGH_01723 2e-113 XK27_00720 S regulation of response to stimulus
ECDMHAGH_01725 1.4e-63 M domain protein
ECDMHAGH_01726 5.7e-308 recN L May be involved in recombinational repair of damaged DNA
ECDMHAGH_01727 3.7e-76 argR K Regulates arginine biosynthesis genes
ECDMHAGH_01728 9.9e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
ECDMHAGH_01729 2.1e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ECDMHAGH_01730 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ECDMHAGH_01731 3.6e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ECDMHAGH_01732 6.8e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ECDMHAGH_01733 7.2e-74 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ECDMHAGH_01734 4.8e-73 yqhY S Asp23 family, cell envelope-related function
ECDMHAGH_01735 1.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ECDMHAGH_01736 6.8e-190 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
ECDMHAGH_01737 1.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
ECDMHAGH_01738 2.2e-57 ysxB J Cysteine protease Prp
ECDMHAGH_01739 3.4e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
ECDMHAGH_01740 4.5e-94 K Transcriptional regulator
ECDMHAGH_01741 3.2e-95 dut S Protein conserved in bacteria
ECDMHAGH_01742 1.8e-178
ECDMHAGH_01743 4e-156
ECDMHAGH_01744 1.1e-223 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ECDMHAGH_01745 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
ECDMHAGH_01746 6e-66 S WxL domain surface cell wall-binding
ECDMHAGH_01747 2e-107
ECDMHAGH_01748 6.2e-241 yifK E Amino acid permease
ECDMHAGH_01749 2.8e-96 K Acetyltransferase (GNAT) domain
ECDMHAGH_01750 1.6e-71 fld C Flavodoxin
ECDMHAGH_01751 7.1e-220 fabV 1.3.1.44, 1.3.1.9 I NAD(P)H binding domain of trans-2-enoyl-CoA reductase
ECDMHAGH_01752 3.6e-185 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECDMHAGH_01753 4.2e-111 S Putative adhesin
ECDMHAGH_01754 6.3e-74 XK27_06920 S Protein of unknown function (DUF1700)
ECDMHAGH_01755 2.7e-54 K Transcriptional regulator PadR-like family
ECDMHAGH_01756 3.8e-104 pncA Q Isochorismatase family
ECDMHAGH_01757 6e-198 srfJ1 3.2.1.45 GH30 M Belongs to the glycosyl hydrolase 30 family
ECDMHAGH_01758 1.3e-67 blt G MFS/sugar transport protein
ECDMHAGH_01759 7e-29 M hydrolase, family 25
ECDMHAGH_01760 1.2e-13
ECDMHAGH_01763 2.9e-27 XK27_10050 K Peptidase S24-like
ECDMHAGH_01764 5.8e-15
ECDMHAGH_01765 0.0 S Predicted membrane protein (DUF2207)
ECDMHAGH_01766 4.8e-26
ECDMHAGH_01767 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
ECDMHAGH_01768 5.7e-208 xynT G MFS/sugar transport protein
ECDMHAGH_01769 6e-61 xynT G MFS/sugar transport protein
ECDMHAGH_01770 2.9e-141 rhaS2 K Transcriptional regulator, AraC family
ECDMHAGH_01771 9.7e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECDMHAGH_01772 5.2e-22
ECDMHAGH_01773 2.9e-148 F DNA/RNA non-specific endonuclease
ECDMHAGH_01774 4.5e-89
ECDMHAGH_01775 6.4e-75 K helix_turn_helix, mercury resistance
ECDMHAGH_01776 2.4e-113
ECDMHAGH_01777 1.9e-135 C Zinc-binding dehydrogenase
ECDMHAGH_01778 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
ECDMHAGH_01779 2.5e-261 G Major Facilitator
ECDMHAGH_01780 1.2e-175 K Transcriptional regulator, LacI family
ECDMHAGH_01781 3.5e-08
ECDMHAGH_01782 1.7e-79
ECDMHAGH_01783 1e-301 E ABC transporter, substratebinding protein
ECDMHAGH_01784 1.4e-248 xylP2 G symporter
ECDMHAGH_01785 1.7e-193 nlhH_1 I alpha/beta hydrolase fold
ECDMHAGH_01786 1.4e-09 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
ECDMHAGH_01787 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
ECDMHAGH_01788 6.7e-19 S integral membrane protein
ECDMHAGH_01789 3.6e-146 G Belongs to the phosphoglycerate mutase family
ECDMHAGH_01790 6.1e-99 speG J Acetyltransferase (GNAT) domain
ECDMHAGH_01791 2.8e-51 sugE P Multidrug resistance protein
ECDMHAGH_01792 5.6e-50 ykkC P Small Multidrug Resistance protein
ECDMHAGH_01793 2.7e-205 gldA 1.1.1.6 C dehydrogenase
ECDMHAGH_01794 6.4e-75
ECDMHAGH_01795 8.9e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
ECDMHAGH_01796 2.8e-185 tdh 1.1.1.14 C Zinc-binding dehydrogenase
ECDMHAGH_01797 1.9e-141 S Membrane
ECDMHAGH_01798 6.8e-71 4.4.1.5 E Glyoxalase
ECDMHAGH_01800 1.3e-91
ECDMHAGH_01801 4.8e-36 hxlR K HxlR-like helix-turn-helix
ECDMHAGH_01802 2.6e-97 EGP Major facilitator Superfamily
ECDMHAGH_01803 1.1e-225 rodA D Cell cycle protein
ECDMHAGH_01804 7.1e-229 opuAB P Binding-protein-dependent transport system inner membrane component
ECDMHAGH_01805 2e-138 P ATPases associated with a variety of cellular activities
ECDMHAGH_01806 3.9e-223 lytR5 K Cell envelope-related transcriptional attenuator domain
ECDMHAGH_01807 1.6e-260 norG_2 K Aminotransferase class I and II
ECDMHAGH_01808 8.2e-140 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H Phosphomethylpyrimidine kinase
ECDMHAGH_01809 4e-84 hmpT S ECF-type riboflavin transporter, S component
ECDMHAGH_01810 2.9e-99 ywlG S Belongs to the UPF0340 family
ECDMHAGH_01811 3e-28 mcbG S Pentapeptide repeats (8 copies)
ECDMHAGH_01812 1.9e-178 K helix_turn _helix lactose operon repressor
ECDMHAGH_01814 7.3e-156 rihA F Inosine-uridine preferring nucleoside hydrolase
ECDMHAGH_01815 2.2e-117 yoaK S Protein of unknown function (DUF1275)
ECDMHAGH_01816 3.5e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
ECDMHAGH_01817 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
ECDMHAGH_01818 0.0 yjcE P Sodium proton antiporter
ECDMHAGH_01819 1.9e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ECDMHAGH_01820 2e-43
ECDMHAGH_01821 4.4e-169 panE2 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ECDMHAGH_01822 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
ECDMHAGH_01823 7.2e-59 K Helix-turn-helix domain
ECDMHAGH_01825 9.3e-292 ytgP S Polysaccharide biosynthesis protein
ECDMHAGH_01826 3.8e-84 iap CBM50 M NlpC P60 family
ECDMHAGH_01827 4.2e-183 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ECDMHAGH_01828 7.9e-114
ECDMHAGH_01829 1.3e-102 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ECDMHAGH_01830 2.4e-204 EGP Major facilitator Superfamily
ECDMHAGH_01831 9.4e-32 arsR K DNA-binding transcription factor activity
ECDMHAGH_01832 3.8e-111 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
ECDMHAGH_01833 1.1e-77 K Winged helix DNA-binding domain
ECDMHAGH_01834 2.5e-50
ECDMHAGH_01836 9e-189 S DNA/RNA non-specific endonuclease
ECDMHAGH_01838 1.3e-26
ECDMHAGH_01839 8.4e-26
ECDMHAGH_01840 8.5e-254 frlA E Amino acid permease
ECDMHAGH_01841 2.8e-157 nanK 2.7.1.2 GK ROK family
ECDMHAGH_01842 4.3e-253 brnQ U Component of the transport system for branched-chain amino acids
ECDMHAGH_01843 1.2e-189 S DUF218 domain
ECDMHAGH_01844 1.9e-163
ECDMHAGH_01845 1.2e-73 K Transcriptional regulator
ECDMHAGH_01846 0.0 pepF2 E Oligopeptidase F
ECDMHAGH_01847 4.2e-175 D Alpha beta
ECDMHAGH_01848 4.5e-126 yoaK S Protein of unknown function (DUF1275)
ECDMHAGH_01849 1.5e-278 rny S Endoribonuclease that initiates mRNA decay
ECDMHAGH_01850 1.5e-247 rarA L recombination factor protein RarA
ECDMHAGH_01851 8.4e-159 akr5f 1.1.1.346 C Aldo keto reductase
ECDMHAGH_01852 1.5e-222 xylR GK ROK family
ECDMHAGH_01853 1.8e-130 K helix_turn_helix, mercury resistance
ECDMHAGH_01854 7.2e-134 XK27_00890 S Domain of unknown function (DUF368)
ECDMHAGH_01855 3e-65 hxlR K HxlR-like helix-turn-helix
ECDMHAGH_01856 7.4e-60 asp2 S Asp23 family, cell envelope-related function
ECDMHAGH_01857 3.6e-70 asp S Asp23 family, cell envelope-related function
ECDMHAGH_01858 5.9e-25
ECDMHAGH_01859 1.4e-90
ECDMHAGH_01860 4.4e-18 S Transglycosylase associated protein
ECDMHAGH_01861 5.5e-156
ECDMHAGH_01862 2e-270 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
ECDMHAGH_01863 5.2e-183 chaT1 U Major Facilitator Superfamily
ECDMHAGH_01864 6.3e-94 laaE K Transcriptional regulator PadR-like family
ECDMHAGH_01865 1e-66 lysM M LysM domain
ECDMHAGH_01866 2.2e-131 XK27_07210 6.1.1.6 S B3 4 domain
ECDMHAGH_01867 6.6e-122 iprA K Cyclic nucleotide-monophosphate binding domain
ECDMHAGH_01868 4.1e-170 arcC 2.7.2.2 E Belongs to the carbamate kinase family
ECDMHAGH_01869 6.8e-217 arcT 2.6.1.1 E Aminotransferase
ECDMHAGH_01870 1.5e-256 arcD E Arginine ornithine antiporter
ECDMHAGH_01871 1.2e-196 argF 2.1.3.3, 2.1.3.6, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECDMHAGH_01872 7.7e-238 arcA 3.5.3.6 E Arginine
ECDMHAGH_01873 2.2e-252 S C4-dicarboxylate anaerobic carrier
ECDMHAGH_01874 5.7e-112 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_01875 5.4e-77 S Iron Transport-associated domain
ECDMHAGH_01876 1.8e-159 M Iron Transport-associated domain
ECDMHAGH_01877 1.1e-88 M Iron Transport-associated domain
ECDMHAGH_01878 5.5e-161 isdE P Periplasmic binding protein
ECDMHAGH_01879 1.1e-170 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECDMHAGH_01880 1.1e-136 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
ECDMHAGH_01881 5.8e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ECDMHAGH_01882 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ECDMHAGH_01883 2.7e-288 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
ECDMHAGH_01884 7.6e-149 licD M LicD family
ECDMHAGH_01885 6e-76 S Domain of unknown function (DUF5067)
ECDMHAGH_01886 2.3e-75 K Transcriptional regulator
ECDMHAGH_01887 1.9e-25
ECDMHAGH_01888 2.7e-79 O OsmC-like protein
ECDMHAGH_01889 8.3e-24
ECDMHAGH_01891 3.2e-13 EGP Major facilitator Superfamily
ECDMHAGH_01892 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
ECDMHAGH_01893 2.6e-181 hrtB V ABC transporter permease
ECDMHAGH_01894 2e-86 ygfC K Bacterial regulatory proteins, tetR family
ECDMHAGH_01895 1.5e-206 ynfM EGP Major facilitator Superfamily
ECDMHAGH_01896 6.6e-62 G Domain of unknown function (DUF386)
ECDMHAGH_01897 2.7e-214 G Sugar (and other) transporter
ECDMHAGH_01898 1.6e-82 G Domain of unknown function (DUF386)
ECDMHAGH_01899 1.3e-128 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
ECDMHAGH_01900 2.5e-145 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
ECDMHAGH_01901 6.9e-236 2.7.1.53 G Xylulose kinase
ECDMHAGH_01902 1.1e-165
ECDMHAGH_01903 1.3e-155 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECDMHAGH_01904 7.2e-141 K helix_turn _helix lactose operon repressor
ECDMHAGH_01905 5.8e-233 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
ECDMHAGH_01906 1e-63 K Bacterial regulatory proteins, tetR family
ECDMHAGH_01907 8.1e-212 mntH P H( )-stimulated, divalent metal cation uptake system
ECDMHAGH_01908 2.6e-129 corA P CorA-like Mg2+ transporter protein
ECDMHAGH_01909 1.3e-11 G leucine binding
ECDMHAGH_01910 6.5e-61 L Helix-turn-helix domain
ECDMHAGH_01911 2.7e-66 L Helix-turn-helix domain
ECDMHAGH_01912 2.6e-40
ECDMHAGH_01913 1.8e-25
ECDMHAGH_01914 0.0 L MobA MobL family protein
ECDMHAGH_01915 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
ECDMHAGH_01916 1.7e-18
ECDMHAGH_01918 0.0 uvrA3 L ABC transporter
ECDMHAGH_01920 1.5e-46
ECDMHAGH_01921 1.2e-83 V VanZ like family
ECDMHAGH_01922 6.1e-82 ohrR K Transcriptional regulator
ECDMHAGH_01923 7.8e-123 S CAAX protease self-immunity
ECDMHAGH_01924 1.5e-36
ECDMHAGH_01925 4.3e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECDMHAGH_01926 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
ECDMHAGH_01927 1.4e-100 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
ECDMHAGH_01928 3.8e-142 S haloacid dehalogenase-like hydrolase
ECDMHAGH_01929 7.2e-86 dck 2.7.1.74 F Deoxynucleoside kinase
ECDMHAGH_01930 3.7e-69 ycgX S Protein of unknown function (DUF1398)
ECDMHAGH_01931 3.4e-120 S GyrI-like small molecule binding domain
ECDMHAGH_01932 6.8e-124 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
ECDMHAGH_01933 6.3e-221 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
ECDMHAGH_01934 4.5e-172 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ECDMHAGH_01935 7.5e-118 yeiL K Cyclic nucleotide-monophosphate binding domain
ECDMHAGH_01936 4e-178 rihB 3.2.2.1, 3.2.2.8 F Nucleoside
ECDMHAGH_01937 8.7e-209 mccF V LD-carboxypeptidase
ECDMHAGH_01938 3.4e-67 K Transcriptional regulator, HxlR family
ECDMHAGH_01939 4e-12
ECDMHAGH_01940 4.7e-224 C Oxidoreductase
ECDMHAGH_01941 1.8e-66 2.3.1.209, 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
ECDMHAGH_01942 4.5e-110 1.6.5.5 C alcohol dehydrogenase
ECDMHAGH_01943 8.7e-54 napB K Transcriptional regulator
ECDMHAGH_01945 2.1e-61 ytrA K helix_turn_helix gluconate operon transcriptional repressor
ECDMHAGH_01946 4.3e-39 ytrB V ABC transporter, ATP-binding protein
ECDMHAGH_01947 1.7e-108 ytrB V ABC transporter, ATP-binding protein
ECDMHAGH_01948 8.4e-176
ECDMHAGH_01949 1.4e-192 KT Putative sugar diacid recognition
ECDMHAGH_01950 9.1e-213 EG GntP family permease
ECDMHAGH_01951 3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ECDMHAGH_01952 2.9e-172 yjcE P Sodium proton antiporter
ECDMHAGH_01953 5e-09 yjcE P Sodium proton antiporter
ECDMHAGH_01954 9.4e-259 ydbT S Bacterial PH domain
ECDMHAGH_01955 1.7e-84 S Bacterial PH domain
ECDMHAGH_01956 2.5e-77 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
ECDMHAGH_01957 8.3e-227 U Belongs to the purine-cytosine permease (2.A.39) family
ECDMHAGH_01958 1.9e-228 arcA 3.5.3.6 E Arginine
ECDMHAGH_01959 7.2e-152 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
ECDMHAGH_01960 1.5e-135 S protein conserved in bacteria
ECDMHAGH_01961 1.4e-104 S Putative glutamine amidotransferase
ECDMHAGH_01962 1.8e-94 K helix_turn _helix lactose operon repressor
ECDMHAGH_01963 2.7e-252 dapE 3.5.1.18 E Peptidase dimerisation domain
ECDMHAGH_01964 4.9e-72 S Sigma factor regulator C-terminal
ECDMHAGH_01965 6e-45 sigM K Sigma-70 region 2
ECDMHAGH_01966 2.4e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ECDMHAGH_01967 2.9e-87
ECDMHAGH_01968 1.3e-55 ypaA S Protein of unknown function (DUF1304)
ECDMHAGH_01969 1.3e-92 S regulation of response to stimulus
ECDMHAGH_01970 3.2e-103 yqeG S HAD phosphatase, family IIIA
ECDMHAGH_01971 1.9e-222 yqeH S Ribosome biogenesis GTPase YqeH
ECDMHAGH_01972 1.3e-48 yhbY J RNA-binding protein
ECDMHAGH_01973 5.9e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ECDMHAGH_01974 4e-107 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
ECDMHAGH_01975 1.6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ECDMHAGH_01976 1.1e-138 yqeM Q Methyltransferase
ECDMHAGH_01977 3.5e-216 ylbM S Belongs to the UPF0348 family
ECDMHAGH_01978 8.6e-96 yceD S Uncharacterized ACR, COG1399
ECDMHAGH_01979 6.9e-29 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ECDMHAGH_01980 1.1e-144 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
ECDMHAGH_01981 8.2e-51 K Transcriptional regulator, ArsR family
ECDMHAGH_01982 2.6e-115 zmp3 O Zinc-dependent metalloprotease
ECDMHAGH_01983 1.9e-194 adhP 1.1.1.1 C alcohol dehydrogenase
ECDMHAGH_01984 6.9e-17 adhP 1.1.1.1 C alcohol dehydrogenase
ECDMHAGH_01985 1.1e-286 macB3 V ABC transporter, ATP-binding protein
ECDMHAGH_01986 3.6e-109 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ECDMHAGH_01987 2.1e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ECDMHAGH_01988 1.8e-139 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ECDMHAGH_01989 9.2e-150 vdlC S Enoyl-(Acyl carrier protein) reductase
ECDMHAGH_01990 1.4e-128 ybbM S Uncharacterised protein family (UPF0014)
ECDMHAGH_01991 2.7e-117 ybbL S ABC transporter, ATP-binding protein
ECDMHAGH_01992 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ECDMHAGH_01993 9.8e-91
ECDMHAGH_01996 1.9e-53 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_01997 2.4e-13 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
ECDMHAGH_01998 4.2e-169 K transcriptional regulator, ArsR family
ECDMHAGH_01999 2.3e-200 abf G Belongs to the glycosyl hydrolase 43 family
ECDMHAGH_02000 6.9e-237 lacY G Oligosaccharide H symporter
ECDMHAGH_02001 2.8e-298 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
ECDMHAGH_02002 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
ECDMHAGH_02003 2.1e-70 K Transcriptional regulator
ECDMHAGH_02004 3.5e-92 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
ECDMHAGH_02005 6.7e-278 pipD E Dipeptidase
ECDMHAGH_02006 1.8e-263 arcD E Arginine ornithine antiporter
ECDMHAGH_02007 0.0 pepN 3.4.11.2 E aminopeptidase
ECDMHAGH_02008 4.3e-73 S Iron-sulphur cluster biosynthesis
ECDMHAGH_02009 0.0 rafA 3.2.1.22 G alpha-galactosidase
ECDMHAGH_02010 1.2e-55 bipA 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Leucine-rich repeat (LRR) protein
ECDMHAGH_02011 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ECDMHAGH_02012 2.1e-100 aacA4_1 4.1.1.17 K acetyltransferase
ECDMHAGH_02013 7e-175 coaA 2.7.1.33 F Pantothenic acid kinase
ECDMHAGH_02014 0.0 helD 3.6.4.12 L DNA helicase
ECDMHAGH_02015 7.7e-290 yjbQ P TrkA C-terminal domain protein
ECDMHAGH_02016 9.1e-121 G phosphoglycerate mutase
ECDMHAGH_02017 1.3e-179 oppF P Belongs to the ABC transporter superfamily
ECDMHAGH_02018 1.3e-204 oppD P Belongs to the ABC transporter superfamily
ECDMHAGH_02019 2.6e-186 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECDMHAGH_02020 2.2e-152 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECDMHAGH_02021 8.8e-306 oppA E ABC transporter, substratebinding protein
ECDMHAGH_02022 6.7e-306 oppA E ABC transporter, substratebinding protein
ECDMHAGH_02023 9.2e-226 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ECDMHAGH_02024 1.4e-108 glnP P ABC transporter permease
ECDMHAGH_02025 1.1e-110 gluC P ABC transporter permease
ECDMHAGH_02026 2.4e-150 glnH ET ABC transporter substrate-binding protein
ECDMHAGH_02027 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
ECDMHAGH_02028 7.3e-172
ECDMHAGH_02029 5.3e-13 3.2.1.14 GH18
ECDMHAGH_02030 4.7e-79 zur P Belongs to the Fur family
ECDMHAGH_02031 2.3e-75 gmk2 2.7.4.8 F Guanylate kinase
ECDMHAGH_02032 2.4e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
ECDMHAGH_02033 3.8e-241 yfnA E Amino Acid
ECDMHAGH_02034 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
ECDMHAGH_02035 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
ECDMHAGH_02036 4.6e-87 M ErfK YbiS YcfS YnhG
ECDMHAGH_02037 6.7e-295 S ABC transporter, ATP-binding protein
ECDMHAGH_02038 4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ECDMHAGH_02039 1.7e-125 XK27_07075 S CAAX protease self-immunity
ECDMHAGH_02040 7.5e-121 cmpC S ATPases associated with a variety of cellular activities
ECDMHAGH_02041 1.7e-168 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
ECDMHAGH_02042 4.7e-166 XK27_00670 S ABC transporter
ECDMHAGH_02043 7.7e-163 degV S Uncharacterised protein, DegV family COG1307
ECDMHAGH_02044 1.1e-178 XK27_08835 S ABC transporter
ECDMHAGH_02045 3.9e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
ECDMHAGH_02046 4.4e-138 XK27_08845 S ABC transporter, ATP-binding protein
ECDMHAGH_02047 3.7e-51 S WxL domain surface cell wall-binding
ECDMHAGH_02048 5.4e-55 S WxL domain surface cell wall-binding
ECDMHAGH_02049 4.5e-114 S Fn3-like domain
ECDMHAGH_02051 9.8e-221
ECDMHAGH_02053 2e-155 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
ECDMHAGH_02054 5.2e-128 terC P integral membrane protein, YkoY family
ECDMHAGH_02055 1.9e-242 pbpX1 V SH3-like domain
ECDMHAGH_02056 6.9e-110 NU mannosyl-glycoprotein
ECDMHAGH_02057 3.7e-182 S DUF218 domain
ECDMHAGH_02058 1.8e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
ECDMHAGH_02059 4.5e-135 IQ reductase
ECDMHAGH_02060 1.9e-15
ECDMHAGH_02061 0.0 ydgH S MMPL family
ECDMHAGH_02062 5.2e-295 E amino acid
ECDMHAGH_02063 1.1e-116 S membrane
ECDMHAGH_02064 4.8e-112 S VIT family
ECDMHAGH_02065 5.7e-91 perR P Belongs to the Fur family
ECDMHAGH_02066 3e-177 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
ECDMHAGH_02068 3e-126 yibF S overlaps another CDS with the same product name
ECDMHAGH_02069 1.8e-201 yibE S overlaps another CDS with the same product name
ECDMHAGH_02071 2.8e-82 uspA T Belongs to the universal stress protein A family
ECDMHAGH_02072 5e-130
ECDMHAGH_02075 3.6e-12 S Membrane
ECDMHAGH_02076 2.2e-279 L Belongs to the 'phage' integrase family
ECDMHAGH_02077 5.4e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
ECDMHAGH_02078 1e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ECDMHAGH_02079 4.2e-138 yhfI S Metallo-beta-lactamase superfamily
ECDMHAGH_02080 1.8e-92 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
ECDMHAGH_02081 9.5e-233 N Uncharacterized conserved protein (DUF2075)
ECDMHAGH_02100 1.8e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
ECDMHAGH_02101 3.3e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
ECDMHAGH_02102 0.0 asnB 6.3.5.4 E Asparagine synthase
ECDMHAGH_02103 4.1e-119 ntcA2 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
ECDMHAGH_02104 5.5e-272 pipD E Peptidase family C69
ECDMHAGH_02105 1.3e-37
ECDMHAGH_02106 0.0
ECDMHAGH_02107 1.8e-38
ECDMHAGH_02108 1.1e-103 S NAD:arginine ADP-ribosyltransferase
ECDMHAGH_02109 1.7e-196 ybiR P Citrate transporter
ECDMHAGH_02110 2.3e-119 yliE T Putative diguanylate phosphodiesterase
ECDMHAGH_02111 1.6e-149 2.7.7.65 T diguanylate cyclase
ECDMHAGH_02112 4.3e-08
ECDMHAGH_02113 8.9e-56
ECDMHAGH_02114 8.8e-50 lmrA V ABC transporter, ATP-binding protein
ECDMHAGH_02115 1.9e-245 lmrA V ABC transporter, ATP-binding protein
ECDMHAGH_02116 0.0 yfiC V ABC transporter
ECDMHAGH_02117 6.7e-195 ampC V Beta-lactamase
ECDMHAGH_02118 1e-49 S NAD:arginine ADP-ribosyltransferase
ECDMHAGH_02119 4e-28
ECDMHAGH_02120 5.6e-29 cspA K Cold shock protein
ECDMHAGH_02121 2e-40
ECDMHAGH_02122 7.5e-32 S Phage gp6-like head-tail connector protein
ECDMHAGH_02123 3.5e-272 S Caudovirus prohead serine protease
ECDMHAGH_02124 1.3e-114 S Phage portal protein
ECDMHAGH_02125 1.6e-60 S Phage portal protein
ECDMHAGH_02127 5.2e-309 terL S overlaps another CDS with the same product name
ECDMHAGH_02128 2e-77 terS L overlaps another CDS with the same product name
ECDMHAGH_02129 9.1e-50 L HNH endonuclease
ECDMHAGH_02130 1.1e-21 S head-tail joining protein
ECDMHAGH_02131 2.3e-08
ECDMHAGH_02132 6.9e-21
ECDMHAGH_02133 7.1e-32 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ECDMHAGH_02134 4e-23 ulaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
ECDMHAGH_02135 4.3e-189 ulaA 2.7.1.194 S PTS system sugar-specific permease component
ECDMHAGH_02136 4.5e-251 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECDMHAGH_02137 2.1e-217 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECDMHAGH_02138 8.1e-107 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
ECDMHAGH_02139 1.1e-53 S Protein of unknown function (DUF1516)
ECDMHAGH_02140 8.6e-75 1.5.1.3 H RibD C-terminal domain
ECDMHAGH_02141 4.9e-252 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ECDMHAGH_02142 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
ECDMHAGH_02143 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
ECDMHAGH_02144 7.8e-97 dps P Belongs to the Dps family
ECDMHAGH_02145 1.1e-25 copZ P Heavy-metal-associated domain
ECDMHAGH_02146 8.7e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
ECDMHAGH_02147 6.2e-51
ECDMHAGH_02148 1.1e-166 lacX 5.1.3.3 G Aldose 1-epimerase
ECDMHAGH_02149 3.2e-99 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ECDMHAGH_02150 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ECDMHAGH_02151 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ECDMHAGH_02152 6.2e-182 K Transcriptional regulator
ECDMHAGH_02153 4.6e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
ECDMHAGH_02154 2.1e-100 zmp1 O PFAM peptidase M10A and M12B, matrixin and adamalysin
ECDMHAGH_02155 2.1e-31
ECDMHAGH_02156 1.7e-57
ECDMHAGH_02157 1.6e-155 pstS P Phosphate
ECDMHAGH_02158 1e-168 pstC P probably responsible for the translocation of the substrate across the membrane
ECDMHAGH_02159 3e-143 pstA P Phosphate transport system permease protein PstA
ECDMHAGH_02160 1.8e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ECDMHAGH_02161 1.3e-204 potD P ABC transporter
ECDMHAGH_02162 9.8e-133 potC P ABC transporter permease
ECDMHAGH_02163 3.8e-148 potB P ABC transporter permease
ECDMHAGH_02164 6.8e-209 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
ECDMHAGH_02165 2.2e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ECDMHAGH_02166 3.6e-236 mntH P H( )-stimulated, divalent metal cation uptake system
ECDMHAGH_02167 3.4e-30
ECDMHAGH_02168 6.2e-58 K Winged helix DNA-binding domain
ECDMHAGH_02169 5.8e-250 S Uncharacterized protein conserved in bacteria (DUF2252)
ECDMHAGH_02170 1.6e-269 frvR K Mga helix-turn-helix domain
ECDMHAGH_02171 9.8e-36
ECDMHAGH_02172 1.2e-100 K Bacterial transcriptional regulator
ECDMHAGH_02173 1.4e-53 kguE 2.7.1.45 G Xylose isomerase-like TIM barrel
ECDMHAGH_02174 8e-10
ECDMHAGH_02175 1.3e-146 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ECDMHAGH_02176 3.5e-138 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ECDMHAGH_02177 7e-128 kdgT P 2-keto-3-deoxygluconate permease
ECDMHAGH_02178 2.1e-110 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
ECDMHAGH_02179 4.2e-81 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
ECDMHAGH_02180 1.4e-128 IQ reductase
ECDMHAGH_02181 6.4e-241 mntH P H( )-stimulated, divalent metal cation uptake system
ECDMHAGH_02182 8.2e-154 S Uncharacterised protein, DegV family COG1307
ECDMHAGH_02183 1.7e-268 nox C NADH oxidase
ECDMHAGH_02184 2.3e-56 trxA1 O Belongs to the thioredoxin family
ECDMHAGH_02185 1.3e-38 yrkD S Metal-sensitive transcriptional repressor
ECDMHAGH_02186 3.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ECDMHAGH_02187 5.4e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ECDMHAGH_02188 2.3e-148 M1-1017
ECDMHAGH_02189 3.7e-162 I Carboxylesterase family
ECDMHAGH_02190 3.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ECDMHAGH_02191 5.5e-163
ECDMHAGH_02192 3.9e-248 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ECDMHAGH_02193 2.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
ECDMHAGH_02194 5.2e-156 lysR5 K LysR substrate binding domain
ECDMHAGH_02195 7.6e-144 yxaA S membrane transporter protein
ECDMHAGH_02196 2e-56 ywjH S Protein of unknown function (DUF1634)
ECDMHAGH_02197 2.3e-139 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
ECDMHAGH_02198 6.8e-226 mdtG EGP Major facilitator Superfamily
ECDMHAGH_02199 7.5e-94 2.7.6.5 S RelA SpoT domain protein
ECDMHAGH_02200 8.1e-28 S Protein of unknown function (DUF2929)
ECDMHAGH_02201 1.4e-167 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ECDMHAGH_02203 0.0 S membrane
ECDMHAGH_02204 4.6e-123 K cheY-homologous receiver domain
ECDMHAGH_02205 1.2e-244 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
ECDMHAGH_02206 6.8e-181 malR K Transcriptional regulator, LacI family
ECDMHAGH_02207 1.6e-88 malT G Major Facilitator
ECDMHAGH_02208 3.5e-149 malT G Major Facilitator
ECDMHAGH_02209 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
ECDMHAGH_02210 2.4e-77
ECDMHAGH_02211 2.3e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ECDMHAGH_02212 1.4e-152 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
ECDMHAGH_02213 4.3e-160 S Alpha/beta hydrolase of unknown function (DUF915)
ECDMHAGH_02214 9.6e-152 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
ECDMHAGH_02215 4.6e-64 K MarR family
ECDMHAGH_02216 3.8e-249 yclG M Parallel beta-helix repeats
ECDMHAGH_02217 5.6e-172 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_02218 4.5e-215 L Transposase
ECDMHAGH_02219 3.3e-42
ECDMHAGH_02221 1.8e-62
ECDMHAGH_02222 1.3e-26 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ECDMHAGH_02223 1.2e-54
ECDMHAGH_02224 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
ECDMHAGH_02225 1.6e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ECDMHAGH_02226 1.8e-59
ECDMHAGH_02227 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECDMHAGH_02228 1.5e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ECDMHAGH_02229 7.6e-112 3.1.3.18 S HAD-hyrolase-like
ECDMHAGH_02230 1.2e-163 yniA G Fructosamine kinase
ECDMHAGH_02231 3e-156 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ECDMHAGH_02232 1.3e-96
ECDMHAGH_02233 8.7e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
ECDMHAGH_02234 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
ECDMHAGH_02235 3.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ECDMHAGH_02236 3.8e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ECDMHAGH_02237 1.4e-188 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ECDMHAGH_02238 1.5e-149 tagG U Transport permease protein
ECDMHAGH_02239 5.7e-241 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
ECDMHAGH_02240 8.6e-173 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ECDMHAGH_02241 4.8e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
ECDMHAGH_02242 1.3e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
ECDMHAGH_02243 1.3e-190 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
ECDMHAGH_02244 1.1e-65 hxlR K Transcriptional regulator, HxlR family
ECDMHAGH_02245 7e-72 yqeY S YqeY-like protein
ECDMHAGH_02246 5.3e-181 phoH T phosphate starvation-inducible protein PhoH
ECDMHAGH_02247 8.5e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ECDMHAGH_02248 3.4e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
ECDMHAGH_02249 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ECDMHAGH_02250 3.3e-149 recO L Involved in DNA repair and RecF pathway recombination
ECDMHAGH_02251 1.5e-177 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
ECDMHAGH_02252 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
ECDMHAGH_02253 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ECDMHAGH_02254 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ECDMHAGH_02255 1.6e-88 K Transcriptional regulator
ECDMHAGH_02256 0.0 ydgH S MMPL family
ECDMHAGH_02257 1.1e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
ECDMHAGH_02258 5.4e-155 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ECDMHAGH_02259 1.2e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
ECDMHAGH_02260 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ECDMHAGH_02261 0.0 dnaE 2.7.7.7 L DNA polymerase
ECDMHAGH_02262 3.6e-126 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
ECDMHAGH_02263 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
ECDMHAGH_02264 1.8e-167 cvfB S S1 domain
ECDMHAGH_02265 9.8e-166 xerD D recombinase XerD
ECDMHAGH_02266 6.9e-71 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ECDMHAGH_02267 2.1e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ECDMHAGH_02268 3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ECDMHAGH_02269 2.7e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ECDMHAGH_02270 1.6e-92 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ECDMHAGH_02271 1.3e-182 ypbB 5.1.3.1 S Helix-turn-helix domain
ECDMHAGH_02272 6.4e-252 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
ECDMHAGH_02273 8e-26 M Lysin motif
ECDMHAGH_02274 6.4e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
ECDMHAGH_02275 1.1e-210 rpsA 1.17.7.4 J Ribosomal protein S1
ECDMHAGH_02276 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
ECDMHAGH_02277 1.5e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ECDMHAGH_02278 3.8e-232 S Tetratricopeptide repeat protein
ECDMHAGH_02279 1.3e-171 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ECDMHAGH_02280 6.4e-221 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ECDMHAGH_02281 0.0 yfmR S ABC transporter, ATP-binding protein
ECDMHAGH_02282 6.3e-187 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ECDMHAGH_02283 2.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ECDMHAGH_02284 2.8e-114 hlyIII S protein, hemolysin III
ECDMHAGH_02285 1.1e-147 DegV S EDD domain protein, DegV family
ECDMHAGH_02286 4e-162 ypmR E GDSL-like Lipase/Acylhydrolase
ECDMHAGH_02287 6.5e-105 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
ECDMHAGH_02288 6.4e-34 yozE S Belongs to the UPF0346 family
ECDMHAGH_02289 9.7e-121
ECDMHAGH_02292 4.3e-30 cinA 3.5.1.42 S Belongs to the CinA family
ECDMHAGH_02294 2e-67 K Transcriptional regulator
ECDMHAGH_02295 2.7e-93 GM NAD(P)H-binding
ECDMHAGH_02296 1.1e-57 S Phosphatidylethanolamine-binding protein
ECDMHAGH_02297 2.5e-43 I sulfurtransferase activity
ECDMHAGH_02298 4.3e-207 S membrane
ECDMHAGH_02299 2.7e-65 K Bacterial regulatory proteins, tetR family
ECDMHAGH_02300 3.6e-199 xerS L Belongs to the 'phage' integrase family
ECDMHAGH_02301 2.5e-69 3.6.1.55 F NUDIX domain
ECDMHAGH_02302 4.7e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ECDMHAGH_02303 1.3e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ECDMHAGH_02304 1.3e-162 arbZ I Phosphate acyltransferases
ECDMHAGH_02305 5.1e-181 arbY M family 8
ECDMHAGH_02306 2.6e-146 arbV 2.3.1.51 I Phosphate acyltransferases
ECDMHAGH_02307 0.0 lmrA 3.6.3.44 V ABC transporter
ECDMHAGH_02308 1.9e-155 arbx M Glycosyl transferase family 8
ECDMHAGH_02309 1.1e-239 codA 3.5.4.1 F cytosine deaminase
ECDMHAGH_02310 8.4e-18 L transposase and inactivated derivatives, IS30 family
ECDMHAGH_02311 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
ECDMHAGH_02312 1.8e-101 K Bacterial regulatory proteins, tetR family
ECDMHAGH_02313 2e-94 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ECDMHAGH_02314 6.5e-229 ndh 1.6.99.3 C NADH dehydrogenase
ECDMHAGH_02315 7.1e-105 ylbE GM NAD(P)H-binding
ECDMHAGH_02316 7e-28
ECDMHAGH_02317 6.8e-73 K Transcriptional regulatory protein, C terminal
ECDMHAGH_02318 8.5e-130 sip L Belongs to the 'phage' integrase family
ECDMHAGH_02319 1.4e-14 K Cro/C1-type HTH DNA-binding domain
ECDMHAGH_02320 1.6e-13 K Cro/C1-type HTH DNA-binding domain
ECDMHAGH_02321 2.6e-70 S Phage regulatory protein Rha (Phage_pRha)
ECDMHAGH_02322 2e-08
ECDMHAGH_02325 5.2e-07
ECDMHAGH_02326 5.3e-67 L Primase C terminal 1 (PriCT-1)
ECDMHAGH_02327 3.7e-159 S Virulence-associated protein E
ECDMHAGH_02328 4.4e-67
ECDMHAGH_02329 1.2e-32 ykzG S Belongs to the UPF0356 family
ECDMHAGH_02330 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ECDMHAGH_02331 2.4e-186 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
ECDMHAGH_02332 1.3e-28
ECDMHAGH_02333 2.4e-106 mltD CBM50 M NlpC P60 family protein
ECDMHAGH_02334 1.3e-161 dprA LU DNA protecting protein DprA
ECDMHAGH_02335 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECDMHAGH_02336 2.2e-176 xerC D Belongs to the 'phage' integrase family. XerC subfamily
ECDMHAGH_02337 1.8e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ECDMHAGH_02338 5.2e-262 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ECDMHAGH_02339 1.8e-43
ECDMHAGH_02340 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
ECDMHAGH_02341 5.5e-124
ECDMHAGH_02342 9.7e-177 sepS16B
ECDMHAGH_02343 3.3e-197 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
ECDMHAGH_02344 1.3e-78 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECDMHAGH_02345 1.8e-56 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
ECDMHAGH_02346 1e-252 bmr3 EGP Major facilitator Superfamily
ECDMHAGH_02347 3.7e-213 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ECDMHAGH_02348 3.3e-108
ECDMHAGH_02349 1.2e-44
ECDMHAGH_02350 3e-96
ECDMHAGH_02351 1.7e-51 ybjQ S Belongs to the UPF0145 family
ECDMHAGH_02352 6.5e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ECDMHAGH_02353 8.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ECDMHAGH_02354 7.9e-186 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ECDMHAGH_02355 8.5e-110 tdk 2.7.1.21 F thymidine kinase
ECDMHAGH_02356 1.4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
ECDMHAGH_02357 1e-133 cobQ S glutamine amidotransferase
ECDMHAGH_02358 6.2e-32 repA S Replication initiator protein A
ECDMHAGH_02360 4.9e-28 uspA T Belongs to the universal stress protein A family
ECDMHAGH_02361 4.5e-166 L PFAM Integrase, catalytic core
ECDMHAGH_02362 4.5e-32 L Putative transposase of IS4/5 family (DUF4096)
ECDMHAGH_02363 1.5e-67 L Putative transposase of IS4/5 family (DUF4096)
ECDMHAGH_02364 1e-75 L Transposase DDE domain
ECDMHAGH_02367 8.1e-119 soj D CobQ CobB MinD ParA nucleotide binding domain protein
ECDMHAGH_02368 1.7e-22 S Family of unknown function (DUF5388)
ECDMHAGH_02369 2.6e-32
ECDMHAGH_02370 2.9e-28 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_02371 5.7e-242 T PhoQ Sensor
ECDMHAGH_02372 6.5e-43
ECDMHAGH_02373 3e-64
ECDMHAGH_02374 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
ECDMHAGH_02375 1.6e-150 corA P CorA-like Mg2+ transporter protein
ECDMHAGH_02376 1.2e-137 pnuC H nicotinamide mononucleotide transporter
ECDMHAGH_02377 5.6e-56 K Winged helix DNA-binding domain
ECDMHAGH_02378 0.0 malL 3.2.1.10, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G Alpha amylase, catalytic domain protein
ECDMHAGH_02379 2.4e-121 yclH V ABC transporter
ECDMHAGH_02380 8e-165 yclI V FtsX-like permease family
ECDMHAGH_02381 7e-196 yubA S AI-2E family transporter
ECDMHAGH_02382 1.3e-106
ECDMHAGH_02383 2.6e-247 M hydrolase, family 25
ECDMHAGH_02384 6.3e-193 ykoT GT2 M Glycosyl transferase family 2
ECDMHAGH_02385 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ECDMHAGH_02386 1.1e-108 M Protein of unknown function (DUF3737)
ECDMHAGH_02387 4.2e-225 patB 4.4.1.8 E Aminotransferase, class I
ECDMHAGH_02388 5.5e-183 yfeX P Peroxidase
ECDMHAGH_02389 8.6e-221 mdtG EGP Major facilitator Superfamily
ECDMHAGH_02390 4.6e-45
ECDMHAGH_02391 2.8e-224 opuCA E ABC transporter, ATP-binding protein
ECDMHAGH_02392 8.8e-105 opuCB E ABC transporter permease
ECDMHAGH_02393 2e-177 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ECDMHAGH_02394 2.1e-109 opuCD P Binding-protein-dependent transport system inner membrane component
ECDMHAGH_02395 1.5e-210
ECDMHAGH_02396 1.9e-262
ECDMHAGH_02397 5e-66 S Tautomerase enzyme
ECDMHAGH_02398 0.0 uvrA2 L ABC transporter
ECDMHAGH_02399 4.6e-99 S Protein of unknown function (DUF1440)
ECDMHAGH_02400 8.1e-249 xylP1 G MFS/sugar transport protein
ECDMHAGH_02401 2.4e-94 K helix_turn_helix multiple antibiotic resistance protein
ECDMHAGH_02402 1.4e-37
ECDMHAGH_02403 1.4e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
ECDMHAGH_02404 1.7e-105 lepB 3.4.21.89 U Belongs to the peptidase S26 family
ECDMHAGH_02405 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
ECDMHAGH_02406 7.3e-122
ECDMHAGH_02407 0.0 oatA I Acyltransferase
ECDMHAGH_02408 4.3e-189 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ECDMHAGH_02409 1.1e-158 xerD L Phage integrase, N-terminal SAM-like domain
ECDMHAGH_02410 3.3e-155 yxkH G Polysaccharide deacetylase
ECDMHAGH_02412 2.5e-67 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
ECDMHAGH_02413 0.0 ctpA 3.6.3.54 P P-type ATPase
ECDMHAGH_02414 8.4e-159 S reductase
ECDMHAGH_02415 7e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ECDMHAGH_02416 1.5e-77 copR K Copper transport repressor CopY TcrY
ECDMHAGH_02417 0.0 copB 3.6.3.4 P P-type ATPase
ECDMHAGH_02418 1.3e-168 EG EamA-like transporter family
ECDMHAGH_02419 4.2e-118 S Elongation factor G-binding protein, N-terminal
ECDMHAGH_02420 5.4e-101 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
ECDMHAGH_02421 1.9e-126
ECDMHAGH_02422 1.2e-277 pipD E Dipeptidase
ECDMHAGH_02423 0.0 pacL1 P P-type ATPase
ECDMHAGH_02424 9.2e-73 K MarR family
ECDMHAGH_02425 1.4e-98 S NADPH-dependent FMN reductase
ECDMHAGH_02426 2.7e-197 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
ECDMHAGH_02427 6.4e-12 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ECDMHAGH_02428 3.6e-269 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ECDMHAGH_02429 4.7e-163 opuBA E ABC transporter, ATP-binding protein
ECDMHAGH_02430 2.2e-67 lrpA K AsnC family
ECDMHAGH_02431 1e-176 adhP 1.1.1.1 C alcohol dehydrogenase
ECDMHAGH_02432 2.2e-90 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_02433 1.7e-17 dltX S D-Ala-teichoic acid biosynthesis protein
ECDMHAGH_02434 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ECDMHAGH_02435 3.8e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
ECDMHAGH_02436 5.2e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ECDMHAGH_02437 3.2e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ECDMHAGH_02438 5.8e-100 gntP EG Gluconate
ECDMHAGH_02439 9.9e-104 gntP EG Gluconate
ECDMHAGH_02440 3.6e-233 potE E amino acid
ECDMHAGH_02441 4.5e-247 fucP G Major Facilitator Superfamily
ECDMHAGH_02442 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
ECDMHAGH_02443 9.9e-77 ctsR K Belongs to the CtsR family
ECDMHAGH_02456 1.1e-11 S Mor transcription activator family
ECDMHAGH_02458 1e-07
ECDMHAGH_02459 1.8e-107 L Integrase
ECDMHAGH_02460 8e-42 S RelB antitoxin
ECDMHAGH_02461 1.6e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
ECDMHAGH_02462 4.1e-07 L transposase and inactivated derivatives, IS30 family
ECDMHAGH_02463 5.9e-92
ECDMHAGH_02464 4.1e-161 L Initiator Replication protein
ECDMHAGH_02466 2.7e-09 K transcriptional regulator
ECDMHAGH_02467 2.1e-141 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
ECDMHAGH_02469 3.4e-25 S HicB_like antitoxin of bacterial toxin-antitoxin system
ECDMHAGH_02470 3.1e-41
ECDMHAGH_02471 2.5e-27
ECDMHAGH_02472 0.0 traA L MobA MobL family protein
ECDMHAGH_02473 5.8e-102 L Psort location Cytoplasmic, score
ECDMHAGH_02474 1.7e-138 EGP Major facilitator Superfamily
ECDMHAGH_02475 7.7e-163 ropB K Helix-turn-helix XRE-family like proteins
ECDMHAGH_02476 4.4e-74 S Protein of unknown function (DUF3290)
ECDMHAGH_02477 1.2e-112 yviA S Protein of unknown function (DUF421)
ECDMHAGH_02478 6.8e-95 I NUDIX domain
ECDMHAGH_02480 7.2e-192 M Glycosyl hydrolases family 25
ECDMHAGH_02482 4.3e-60 S Bacteriophage holin family
ECDMHAGH_02483 2.8e-21
ECDMHAGH_02486 6.3e-07 M Glycosyl transferases group 1
ECDMHAGH_02487 9.5e-15 licD M LICD family
ECDMHAGH_02488 1.6e-193 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_02489 4.3e-15 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_02490 2.6e-159 S Bacterial SH3 domain
ECDMHAGH_02491 4.4e-29
ECDMHAGH_02492 2.2e-44 M hydrolase, family 25
ECDMHAGH_02493 1.2e-86 ccl S QueT transporter
ECDMHAGH_02494 0.0 S Bacterial membrane protein YfhO
ECDMHAGH_02495 6.9e-167 2.5.1.74 H UbiA prenyltransferase family
ECDMHAGH_02496 8.6e-118 drrB U ABC-2 type transporter
ECDMHAGH_02497 9.6e-164 drrA V ABC transporter
ECDMHAGH_02498 5e-93 K helix_turn_helix multiple antibiotic resistance protein
ECDMHAGH_02499 5.9e-228 pbuG S permease
ECDMHAGH_02500 8.2e-182 iolS C Aldo keto reductase
ECDMHAGH_02501 3.9e-102 GM NAD(P)H-binding
ECDMHAGH_02502 1.3e-58
ECDMHAGH_02503 1.5e-183 xynD 3.5.1.104 G polysaccharide deacetylase
ECDMHAGH_02504 5.9e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
ECDMHAGH_02505 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
ECDMHAGH_02506 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
ECDMHAGH_02507 6.9e-167
ECDMHAGH_02508 7.1e-141 K Helix-turn-helix domain
ECDMHAGH_02509 4e-192 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECDMHAGH_02510 1.9e-94 qorB 1.6.5.2 GM NmrA-like family
ECDMHAGH_02511 1.9e-69 K Transcriptional regulator
ECDMHAGH_02512 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
ECDMHAGH_02513 2.2e-171 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
ECDMHAGH_02514 3.2e-133 1.1.1.219 GM Male sterility protein
ECDMHAGH_02515 4.9e-50 K Bacterial regulatory proteins, tetR family
ECDMHAGH_02516 6.8e-28 K helix_turn_helix, mercury resistance
ECDMHAGH_02517 7.6e-62 yliE T EAL domain
ECDMHAGH_02518 7.3e-102 S Alpha beta hydrolase
ECDMHAGH_02519 1.6e-77 GM NmrA-like family
ECDMHAGH_02520 2.9e-57 adhR K MerR, DNA binding
ECDMHAGH_02521 3.4e-48 C Flavodoxin
ECDMHAGH_02522 6.9e-179 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
ECDMHAGH_02524 3.4e-37 T Cyclic nucleotide-binding protein
ECDMHAGH_02525 3.5e-63 1.6.5.2 S NADPH-dependent FMN reductase
ECDMHAGH_02526 2.7e-133 lmrB EGP Major facilitator Superfamily
ECDMHAGH_02527 2.2e-55 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ECDMHAGH_02528 1.6e-42 K helix_turn_helix multiple antibiotic resistance protein
ECDMHAGH_02529 1.6e-160 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M MucBP domain
ECDMHAGH_02530 9.5e-70 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
ECDMHAGH_02531 5.5e-43 M Mycoplasma protein of unknown function, DUF285
ECDMHAGH_02532 2.3e-245 M Mycoplasma protein of unknown function, DUF285
ECDMHAGH_02533 9.8e-71
ECDMHAGH_02534 2e-26 K Transcriptional
ECDMHAGH_02535 1.6e-224 LO Uncharacterized conserved protein (DUF2075)
ECDMHAGH_02536 3.6e-114 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
ECDMHAGH_02537 6.8e-26
ECDMHAGH_02538 1.3e-122
ECDMHAGH_02539 3.2e-107 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
ECDMHAGH_02540 4e-204 pmrB EGP Major facilitator Superfamily
ECDMHAGH_02541 1.7e-72 S COG NOG18757 non supervised orthologous group
ECDMHAGH_02542 1.3e-167 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_02543 9.4e-16 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_02544 2.8e-53 K Bacterial regulatory proteins, tetR family
ECDMHAGH_02545 2.7e-132 IQ reductase
ECDMHAGH_02546 1.1e-231 EK Aminotransferase, class I
ECDMHAGH_02547 6.6e-247 uxuT G MFS/sugar transport protein
ECDMHAGH_02548 1.7e-174 picA 3.2.1.67 G Glycosyl hydrolases family 28
ECDMHAGH_02549 5.8e-18 L PFAM Integrase, catalytic core
ECDMHAGH_02550 4e-111 K Primase C terminal 1 (PriCT-1)
ECDMHAGH_02551 2.4e-135 D Cellulose biosynthesis protein BcsQ
ECDMHAGH_02552 2.6e-08
ECDMHAGH_02553 4.4e-113 L Psort location Cytoplasmic, score
ECDMHAGH_02554 1e-102 tnpR L Resolvase, N terminal domain
ECDMHAGH_02555 6e-149 S Uncharacterised protein, DegV family COG1307
ECDMHAGH_02556 1.6e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ECDMHAGH_02557 8e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ECDMHAGH_02559 4.6e-85 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
ECDMHAGH_02560 2.1e-195 EGP Major facilitator Superfamily
ECDMHAGH_02561 2.1e-200 EGP Major facilitator Superfamily
ECDMHAGH_02562 6e-157 dkgB S reductase
ECDMHAGH_02563 3.2e-132 U Relaxase/Mobilisation nuclease domain
ECDMHAGH_02564 2.1e-34 S Bacterial mobilisation protein (MobC)
ECDMHAGH_02565 3.5e-118 L Initiator Replication protein
ECDMHAGH_02566 3.3e-84 zmp2 O Zinc-dependent metalloprotease
ECDMHAGH_02579 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
ECDMHAGH_02580 1.1e-166 L Transposase and inactivated derivatives, IS30 family
ECDMHAGH_02581 9.6e-202 S Domain of unknown function (DUF4432)
ECDMHAGH_02582 1.4e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECDMHAGH_02583 3.6e-120
ECDMHAGH_02584 2.3e-95 J glyoxalase III activity
ECDMHAGH_02585 3.5e-88 rmeB K transcriptional regulator, MerR family
ECDMHAGH_02586 9.2e-30 K Helix-turn-helix XRE-family like proteins
ECDMHAGH_02588 1e-185 mod 2.1.1.72, 3.1.21.5 L DNA methylase
ECDMHAGH_02589 1.7e-103 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)