ORF_ID e_value Gene_name EC_number CAZy COGs Description
LKLMECAK_00001 1.1e-86 pksJ Q Polyketide synthase of type I
LKLMECAK_00002 1.1e-127 IQ reductase
LKLMECAK_00003 1.7e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LKLMECAK_00006 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LKLMECAK_00007 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
LKLMECAK_00008 3e-159 K LysR substrate binding domain
LKLMECAK_00009 1.6e-49 S GlpM protein
LKLMECAK_00010 4.8e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LKLMECAK_00011 1.8e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LKLMECAK_00012 6.1e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LKLMECAK_00013 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LKLMECAK_00014 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LKLMECAK_00015 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKLMECAK_00016 2.4e-25 yqzJ
LKLMECAK_00017 5e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKLMECAK_00018 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
LKLMECAK_00019 1.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LKLMECAK_00020 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
LKLMECAK_00022 3.1e-95 yqjB S protein conserved in bacteria
LKLMECAK_00023 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
LKLMECAK_00024 3.8e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LKLMECAK_00025 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
LKLMECAK_00026 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
LKLMECAK_00027 1e-75 yqiW S Belongs to the UPF0403 family
LKLMECAK_00028 1.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LKLMECAK_00029 3.7e-203 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKLMECAK_00030 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKLMECAK_00031 2.1e-161 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKLMECAK_00032 2.9e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKLMECAK_00033 1.6e-205 buk 2.7.2.7 C Belongs to the acetokinase family
LKLMECAK_00034 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
LKLMECAK_00035 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
LKLMECAK_00036 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
LKLMECAK_00037 3.2e-34 yqzF S Protein of unknown function (DUF2627)
LKLMECAK_00038 1.8e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LKLMECAK_00039 8.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
LKLMECAK_00040 9.4e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
LKLMECAK_00041 1.3e-202 mmgC I acyl-CoA dehydrogenase
LKLMECAK_00042 2.5e-155 hbdA 1.1.1.157 I Dehydrogenase
LKLMECAK_00043 2.4e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
LKLMECAK_00044 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LKLMECAK_00045 8.8e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
LKLMECAK_00046 4.2e-17
LKLMECAK_00047 7.7e-101 ytaF P Probably functions as a manganese efflux pump
LKLMECAK_00048 1.2e-112 K Protein of unknown function (DUF1232)
LKLMECAK_00050 4.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LKLMECAK_00053 2.6e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKLMECAK_00054 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LKLMECAK_00055 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
LKLMECAK_00056 0.0 recN L May be involved in recombinational repair of damaged DNA
LKLMECAK_00057 3.9e-78 argR K Regulates arginine biosynthesis genes
LKLMECAK_00058 1.3e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
LKLMECAK_00059 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LKLMECAK_00060 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LKLMECAK_00061 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKLMECAK_00062 6.7e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKLMECAK_00063 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LKLMECAK_00064 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LKLMECAK_00065 8.1e-67 yqhY S protein conserved in bacteria
LKLMECAK_00066 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LKLMECAK_00067 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LKLMECAK_00068 2.5e-62 spoIIIAH S SpoIIIAH-like protein
LKLMECAK_00069 1.1e-116 spoIIIAG S stage III sporulation protein AG
LKLMECAK_00070 2.6e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
LKLMECAK_00071 6.3e-200 spoIIIAE S stage III sporulation protein AE
LKLMECAK_00072 2.5e-41 spoIIIAD S Stage III sporulation protein AD
LKLMECAK_00073 7.6e-29 spoIIIAC S stage III sporulation protein AC
LKLMECAK_00074 1.6e-83 spoIIIAB S Stage III sporulation protein
LKLMECAK_00075 1.6e-171 spoIIIAA S stage III sporulation protein AA
LKLMECAK_00076 1.8e-36 yqhV S Protein of unknown function (DUF2619)
LKLMECAK_00077 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LKLMECAK_00078 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LKLMECAK_00079 3.7e-88 yqhR S Conserved membrane protein YqhR
LKLMECAK_00080 1.2e-172 yqhQ S Protein of unknown function (DUF1385)
LKLMECAK_00081 5.8e-62 yqhP
LKLMECAK_00082 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
LKLMECAK_00083 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LKLMECAK_00084 7.5e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LKLMECAK_00085 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
LKLMECAK_00086 1.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LKLMECAK_00087 2.3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LKLMECAK_00088 1.5e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
LKLMECAK_00089 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LKLMECAK_00090 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
LKLMECAK_00091 5.2e-23 sinI S Anti-repressor SinI
LKLMECAK_00092 7.8e-55 sinR K transcriptional
LKLMECAK_00093 1.6e-140 tasA S Cell division protein FtsN
LKLMECAK_00094 1.9e-69 sipW 3.4.21.89 U Signal peptidase
LKLMECAK_00095 1.2e-120 yqxM
LKLMECAK_00096 1.1e-53 yqzG S Protein of unknown function (DUF3889)
LKLMECAK_00097 2.3e-26 yqzE S YqzE-like protein
LKLMECAK_00098 1e-60 S ComG operon protein 7
LKLMECAK_00099 1.6e-64 comGF U Putative Competence protein ComGF
LKLMECAK_00100 1.3e-19 comGE
LKLMECAK_00101 2.9e-70 gspH NU Tfp pilus assembly protein FimT
LKLMECAK_00102 8.9e-50 comGC U Required for transformation and DNA binding
LKLMECAK_00103 3.2e-184 comGB NU COG1459 Type II secretory pathway, component PulF
LKLMECAK_00104 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LKLMECAK_00105 1.2e-185 corA P Mg2 transporter protein
LKLMECAK_00106 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LKLMECAK_00107 6.5e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKLMECAK_00109 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
LKLMECAK_00110 3.1e-37 yqgY S Protein of unknown function (DUF2626)
LKLMECAK_00111 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LKLMECAK_00112 5.4e-20 yqgW S Protein of unknown function (DUF2759)
LKLMECAK_00113 4.5e-49 yqgV S Thiamine-binding protein
LKLMECAK_00114 1.1e-197 yqgU
LKLMECAK_00115 1.2e-216 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
LKLMECAK_00116 2.2e-179 glcK 2.7.1.2 G Glucokinase
LKLMECAK_00117 1e-230 nhaC C Na H antiporter
LKLMECAK_00118 4e-07 yqgO
LKLMECAK_00119 1e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LKLMECAK_00120 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LKLMECAK_00121 1.2e-50 yqzD
LKLMECAK_00122 1.1e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LKLMECAK_00123 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKLMECAK_00124 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKLMECAK_00125 2.9e-154 pstA P Phosphate transport system permease
LKLMECAK_00126 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
LKLMECAK_00127 7.6e-158 pstS P Phosphate
LKLMECAK_00128 0.0 pbpA 3.4.16.4 M penicillin-binding protein
LKLMECAK_00129 3.4e-228 yqgE EGP Major facilitator superfamily
LKLMECAK_00130 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
LKLMECAK_00131 2.9e-71 yqgC S protein conserved in bacteria
LKLMECAK_00132 2.4e-128 yqgB S Protein of unknown function (DUF1189)
LKLMECAK_00133 3.1e-47 yqfZ M LysM domain
LKLMECAK_00134 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LKLMECAK_00135 2.3e-52 yqfX S membrane
LKLMECAK_00136 3.2e-109 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
LKLMECAK_00137 2.9e-72 zur P Belongs to the Fur family
LKLMECAK_00138 5.3e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LKLMECAK_00139 9.3e-37 yqfT S Protein of unknown function (DUF2624)
LKLMECAK_00140 1.3e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LKLMECAK_00141 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LKLMECAK_00142 3.7e-43 yqfQ S YqfQ-like protein
LKLMECAK_00143 6.5e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LKLMECAK_00144 2.1e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LKLMECAK_00145 1.4e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
LKLMECAK_00146 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
LKLMECAK_00147 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LKLMECAK_00148 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LKLMECAK_00149 6.1e-88 yaiI S Belongs to the UPF0178 family
LKLMECAK_00150 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LKLMECAK_00151 4.5e-112 ccpN K CBS domain
LKLMECAK_00152 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LKLMECAK_00153 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LKLMECAK_00154 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
LKLMECAK_00155 1.8e-16 S YqzL-like protein
LKLMECAK_00156 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LKLMECAK_00157 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LKLMECAK_00158 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LKLMECAK_00159 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LKLMECAK_00160 0.0 yqfF S membrane-associated HD superfamily hydrolase
LKLMECAK_00161 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
LKLMECAK_00162 5.7e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
LKLMECAK_00163 9.3e-46 yqfC S sporulation protein YqfC
LKLMECAK_00164 9.9e-47 yqfB
LKLMECAK_00165 3.8e-118 yqfA S UPF0365 protein
LKLMECAK_00166 5.7e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
LKLMECAK_00167 8e-68 yqeY S Yqey-like protein
LKLMECAK_00168 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LKLMECAK_00169 3.3e-156 yqeW P COG1283 Na phosphate symporter
LKLMECAK_00170 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
LKLMECAK_00171 3.9e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LKLMECAK_00172 6.6e-173 prmA J Methylates ribosomal protein L11
LKLMECAK_00173 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LKLMECAK_00174 0.0 dnaK O Heat shock 70 kDa protein
LKLMECAK_00175 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LKLMECAK_00176 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LKLMECAK_00177 8.5e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
LKLMECAK_00178 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LKLMECAK_00179 2.5e-53 yqxA S Protein of unknown function (DUF3679)
LKLMECAK_00180 7.8e-219 spoIIP M stage II sporulation protein P
LKLMECAK_00181 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LKLMECAK_00182 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
LKLMECAK_00183 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
LKLMECAK_00184 0.0 comEC S Competence protein ComEC
LKLMECAK_00185 8e-105 comEB 3.5.4.12 F ComE operon protein 2
LKLMECAK_00186 9.6e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
LKLMECAK_00187 3.8e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKLMECAK_00188 1.1e-138 yqeM Q Methyltransferase
LKLMECAK_00189 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LKLMECAK_00190 2.9e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LKLMECAK_00191 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LKLMECAK_00192 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
LKLMECAK_00193 1.2e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LKLMECAK_00194 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LKLMECAK_00195 7.6e-94 yqeG S hydrolase of the HAD superfamily
LKLMECAK_00197 2.5e-138 yqeF E GDSL-like Lipase/Acylhydrolase
LKLMECAK_00198 3.8e-139 3.5.1.104 G Polysaccharide deacetylase
LKLMECAK_00199 8e-106 yqeD S SNARE associated Golgi protein
LKLMECAK_00200 8.8e-213 EGP Major facilitator Superfamily
LKLMECAK_00201 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKLMECAK_00202 1.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
LKLMECAK_00203 2.1e-91 K Transcriptional regulator PadR-like family
LKLMECAK_00204 3.4e-147 ydeE K AraC family transcriptional regulator
LKLMECAK_00205 9.2e-95 adk 2.7.4.3 F adenylate kinase activity
LKLMECAK_00207 1.5e-218 tetL EGP Major facilitator Superfamily
LKLMECAK_00208 6.7e-82 yyaR K Acetyltransferase (GNAT) domain
LKLMECAK_00209 8.9e-92 yrdA S DinB family
LKLMECAK_00211 4.2e-144 S hydrolase
LKLMECAK_00212 3.9e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
LKLMECAK_00213 5.9e-129 glvR K Helix-turn-helix domain, rpiR family
LKLMECAK_00214 3.8e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
LKLMECAK_00215 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
LKLMECAK_00216 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
LKLMECAK_00217 8.7e-181 romA S Beta-lactamase superfamily domain
LKLMECAK_00218 2.6e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LKLMECAK_00219 5.9e-163 yybE K Transcriptional regulator
LKLMECAK_00220 1.9e-212 ynfM EGP Major facilitator Superfamily
LKLMECAK_00221 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LKLMECAK_00222 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
LKLMECAK_00223 1.3e-77 yrhH Q methyltransferase
LKLMECAK_00225 8e-143 focA P Formate nitrite
LKLMECAK_00226 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
LKLMECAK_00227 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
LKLMECAK_00228 7e-81 yrhD S Protein of unknown function (DUF1641)
LKLMECAK_00229 5.1e-34 yrhC S YrhC-like protein
LKLMECAK_00230 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LKLMECAK_00231 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
LKLMECAK_00232 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LKLMECAK_00233 1e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
LKLMECAK_00234 4.1e-27 yrzA S Protein of unknown function (DUF2536)
LKLMECAK_00235 8.1e-70 yrrS S Protein of unknown function (DUF1510)
LKLMECAK_00236 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
LKLMECAK_00237 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LKLMECAK_00238 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
LKLMECAK_00239 3.9e-245 yegQ O COG0826 Collagenase and related proteases
LKLMECAK_00240 2.9e-173 yegQ O Peptidase U32
LKLMECAK_00241 4.7e-117 yrrM 2.1.1.104 S O-methyltransferase
LKLMECAK_00242 1.2e-189 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LKLMECAK_00243 7.1e-46 yrzB S Belongs to the UPF0473 family
LKLMECAK_00244 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LKLMECAK_00245 8.5e-41 yrzL S Belongs to the UPF0297 family
LKLMECAK_00246 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LKLMECAK_00247 2e-162 yrrI S AI-2E family transporter
LKLMECAK_00248 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LKLMECAK_00249 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
LKLMECAK_00250 6.1e-109 gluC P ABC transporter
LKLMECAK_00251 2.9e-106 glnP P ABC transporter
LKLMECAK_00252 2.1e-08 S Protein of unknown function (DUF3918)
LKLMECAK_00253 2.9e-30 yrzR
LKLMECAK_00254 3.4e-82 yrrD S protein conserved in bacteria
LKLMECAK_00255 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LKLMECAK_00256 1.7e-18 S COG0457 FOG TPR repeat
LKLMECAK_00257 2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LKLMECAK_00258 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
LKLMECAK_00259 7.8e-64 cymR K Transcriptional regulator
LKLMECAK_00260 2.8e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LKLMECAK_00261 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LKLMECAK_00262 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LKLMECAK_00263 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
LKLMECAK_00266 2.5e-273 lytH 3.5.1.28 M COG3103 SH3 domain protein
LKLMECAK_00267 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LKLMECAK_00268 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LKLMECAK_00269 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LKLMECAK_00270 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LKLMECAK_00271 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
LKLMECAK_00272 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
LKLMECAK_00273 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LKLMECAK_00274 8.5e-50 yrzD S Post-transcriptional regulator
LKLMECAK_00275 1.8e-271 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKLMECAK_00276 9.5e-110 yrbG S membrane
LKLMECAK_00277 2.4e-60 yrzE S Protein of unknown function (DUF3792)
LKLMECAK_00278 2.5e-37 yajC U Preprotein translocase subunit YajC
LKLMECAK_00279 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LKLMECAK_00280 1.6e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LKLMECAK_00281 1.6e-20 yrzS S Protein of unknown function (DUF2905)
LKLMECAK_00282 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LKLMECAK_00283 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LKLMECAK_00284 3.7e-93 bofC S BofC C-terminal domain
LKLMECAK_00286 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKLMECAK_00287 1.2e-126 safA M spore coat assembly protein SafA
LKLMECAK_00288 7.7e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LKLMECAK_00289 2.2e-151 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
LKLMECAK_00290 9.7e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
LKLMECAK_00291 1.5e-222 nifS 2.8.1.7 E Cysteine desulfurase
LKLMECAK_00292 1.3e-93 niaR S small molecule binding protein (contains 3H domain)
LKLMECAK_00293 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
LKLMECAK_00294 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
LKLMECAK_00295 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LKLMECAK_00296 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
LKLMECAK_00297 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LKLMECAK_00298 3.2e-56 ysxB J ribosomal protein
LKLMECAK_00299 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
LKLMECAK_00300 4.6e-160 spoIVFB S Stage IV sporulation protein
LKLMECAK_00301 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
LKLMECAK_00302 2.3e-142 minD D Belongs to the ParA family
LKLMECAK_00303 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LKLMECAK_00304 5.4e-84 mreD M shape-determining protein
LKLMECAK_00305 3.6e-157 mreC M Involved in formation and maintenance of cell shape
LKLMECAK_00306 4e-184 mreB D Rod shape-determining protein MreB
LKLMECAK_00307 5.3e-127 radC E Belongs to the UPF0758 family
LKLMECAK_00308 2.1e-97 maf D septum formation protein Maf
LKLMECAK_00309 1.4e-136 spoIIB S Sporulation related domain
LKLMECAK_00310 1.1e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LKLMECAK_00311 1.4e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LKLMECAK_00312 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LKLMECAK_00313 2.1e-25
LKLMECAK_00314 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LKLMECAK_00315 6.4e-223 spoVID M stage VI sporulation protein D
LKLMECAK_00316 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LKLMECAK_00317 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
LKLMECAK_00318 1.6e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LKLMECAK_00319 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LKLMECAK_00320 1e-145 hemX O cytochrome C
LKLMECAK_00321 3.8e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LKLMECAK_00322 3.8e-87 ysxD
LKLMECAK_00323 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
LKLMECAK_00324 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LKLMECAK_00325 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
LKLMECAK_00326 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LKLMECAK_00327 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LKLMECAK_00328 1e-187 ysoA H Tetratricopeptide repeat
LKLMECAK_00329 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LKLMECAK_00330 9.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LKLMECAK_00331 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LKLMECAK_00332 1.8e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LKLMECAK_00333 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LKLMECAK_00334 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
LKLMECAK_00335 0.0 ilvB 2.2.1.6 E Acetolactate synthase
LKLMECAK_00340 5.9e-91 ysnB S Phosphoesterase
LKLMECAK_00341 4.2e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LKLMECAK_00342 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LKLMECAK_00343 5.3e-198 gerM S COG5401 Spore germination protein
LKLMECAK_00344 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LKLMECAK_00345 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
LKLMECAK_00346 2e-30 gerE K Transcriptional regulator
LKLMECAK_00347 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
LKLMECAK_00348 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LKLMECAK_00349 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LKLMECAK_00350 4.8e-108 sdhC C succinate dehydrogenase
LKLMECAK_00351 2e-79 yslB S Protein of unknown function (DUF2507)
LKLMECAK_00352 9.2e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LKLMECAK_00353 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LKLMECAK_00354 2.5e-52 trxA O Belongs to the thioredoxin family
LKLMECAK_00355 8e-298 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
LKLMECAK_00356 1.6e-177 etfA C Electron transfer flavoprotein
LKLMECAK_00357 2.8e-137 etfB C Electron transfer flavoprotein
LKLMECAK_00358 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LKLMECAK_00359 2.7e-103 fadR K Transcriptional regulator
LKLMECAK_00360 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LKLMECAK_00361 8.6e-89 ywbB S Protein of unknown function (DUF2711)
LKLMECAK_00362 4.7e-67 yshE S membrane
LKLMECAK_00363 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LKLMECAK_00364 0.0 polX L COG1796 DNA polymerase IV (family X)
LKLMECAK_00365 1.8e-82 cvpA S membrane protein, required for colicin V production
LKLMECAK_00366 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LKLMECAK_00367 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKLMECAK_00368 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKLMECAK_00369 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LKLMECAK_00370 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKLMECAK_00371 2e-32 sspI S Belongs to the SspI family
LKLMECAK_00372 2.7e-202 ysfB KT regulator
LKLMECAK_00373 1.6e-258 glcD 1.1.3.15 C FAD binding domain
LKLMECAK_00374 2e-255 glcF C Glycolate oxidase
LKLMECAK_00375 0.0 cstA T Carbon starvation protein
LKLMECAK_00376 8.6e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
LKLMECAK_00377 1.2e-144 araQ G transport system permease
LKLMECAK_00378 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
LKLMECAK_00379 2.9e-251 araN G carbohydrate transport
LKLMECAK_00380 1.2e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LKLMECAK_00381 1.7e-140 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LKLMECAK_00382 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LKLMECAK_00383 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
LKLMECAK_00384 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
LKLMECAK_00385 1.5e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LKLMECAK_00386 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
LKLMECAK_00387 1.9e-65 ysdB S Sigma-w pathway protein YsdB
LKLMECAK_00388 2.6e-42 ysdA S Membrane
LKLMECAK_00389 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LKLMECAK_00390 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LKLMECAK_00391 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LKLMECAK_00392 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LKLMECAK_00393 3.8e-38 lrgA S effector of murein hydrolase LrgA
LKLMECAK_00394 1.2e-129 lytT T COG3279 Response regulator of the LytR AlgR family
LKLMECAK_00395 0.0 lytS 2.7.13.3 T Histidine kinase
LKLMECAK_00396 3.9e-150 ysaA S HAD-hyrolase-like
LKLMECAK_00397 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LKLMECAK_00398 2e-152 ytxC S YtxC-like family
LKLMECAK_00399 2.1e-106 ytxB S SNARE associated Golgi protein
LKLMECAK_00400 9.5e-172 dnaI L Primosomal protein DnaI
LKLMECAK_00401 3.1e-251 dnaB L Membrane attachment protein
LKLMECAK_00402 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LKLMECAK_00403 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LKLMECAK_00404 9.7e-194 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKLMECAK_00405 2e-67 ytcD K Transcriptional regulator
LKLMECAK_00406 4.5e-206 ytbD EGP Major facilitator Superfamily
LKLMECAK_00407 1.7e-159 ytbE S reductase
LKLMECAK_00408 2e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LKLMECAK_00409 2.1e-106 ytaF P Probably functions as a manganese efflux pump
LKLMECAK_00410 9.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LKLMECAK_00411 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LKLMECAK_00412 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
LKLMECAK_00413 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKLMECAK_00414 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
LKLMECAK_00415 1.2e-241 icd 1.1.1.42 C isocitrate
LKLMECAK_00416 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
LKLMECAK_00417 2.1e-46 yjdF S Protein of unknown function (DUF2992)
LKLMECAK_00418 1.1e-72 yeaL S membrane
LKLMECAK_00419 2.4e-193 ytvI S sporulation integral membrane protein YtvI
LKLMECAK_00420 3.5e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
LKLMECAK_00421 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LKLMECAK_00422 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LKLMECAK_00423 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LKLMECAK_00424 4.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LKLMECAK_00425 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
LKLMECAK_00426 0.0 dnaE 2.7.7.7 L DNA polymerase
LKLMECAK_00427 3.2e-56 ytrH S Sporulation protein YtrH
LKLMECAK_00428 4.3e-86 ytrI
LKLMECAK_00429 5.8e-23
LKLMECAK_00430 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
LKLMECAK_00431 1.5e-46 ytpI S YtpI-like protein
LKLMECAK_00432 1.7e-236 ytoI K transcriptional regulator containing CBS domains
LKLMECAK_00433 1.3e-128 ytkL S Belongs to the UPF0173 family
LKLMECAK_00434 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKLMECAK_00436 7e-264 argH 4.3.2.1 E argininosuccinate lyase
LKLMECAK_00437 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LKLMECAK_00438 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
LKLMECAK_00439 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LKLMECAK_00440 9.1e-181 ytxK 2.1.1.72 L DNA methylase
LKLMECAK_00441 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LKLMECAK_00442 1.6e-60 ytfJ S Sporulation protein YtfJ
LKLMECAK_00443 1e-93 ytfI S Protein of unknown function (DUF2953)
LKLMECAK_00444 4.5e-88 yteJ S RDD family
LKLMECAK_00445 6.4e-182 sppA OU signal peptide peptidase SppA
LKLMECAK_00446 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LKLMECAK_00447 8.8e-311 ytcJ S amidohydrolase
LKLMECAK_00448 4.2e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LKLMECAK_00449 3.9e-31 sspB S spore protein
LKLMECAK_00450 2.8e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LKLMECAK_00451 2.3e-207 iscS2 2.8.1.7 E Cysteine desulfurase
LKLMECAK_00452 2.6e-239 braB E Component of the transport system for branched-chain amino acids
LKLMECAK_00453 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LKLMECAK_00454 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LKLMECAK_00455 1.7e-108 yttP K Transcriptional regulator
LKLMECAK_00456 4.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
LKLMECAK_00457 9.5e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
LKLMECAK_00458 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LKLMECAK_00459 2.3e-251 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LKLMECAK_00460 1.7e-99 yokH G SMI1 / KNR4 family
LKLMECAK_00461 1.5e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LKLMECAK_00462 2.5e-09
LKLMECAK_00463 2.2e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
LKLMECAK_00465 2.6e-135 E GDSL-like Lipase/Acylhydrolase family
LKLMECAK_00466 1.1e-148 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKLMECAK_00467 2.8e-148 K Transcriptional regulator
LKLMECAK_00468 5.2e-125 azlC E AzlC protein
LKLMECAK_00469 2.1e-46 azlD S Branched-chain amino acid transport protein (AzlD)
LKLMECAK_00470 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKLMECAK_00471 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LKLMECAK_00472 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LKLMECAK_00473 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
LKLMECAK_00474 4e-228 acuC BQ histone deacetylase
LKLMECAK_00475 1.1e-119 motS N Flagellar motor protein
LKLMECAK_00476 6.6e-145 motA N flagellar motor
LKLMECAK_00477 6.4e-182 ccpA K catabolite control protein A
LKLMECAK_00478 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LKLMECAK_00479 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
LKLMECAK_00480 1.7e-16 ytxH S COG4980 Gas vesicle protein
LKLMECAK_00481 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LKLMECAK_00482 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LKLMECAK_00483 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
LKLMECAK_00484 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKLMECAK_00485 3.7e-148 ytpQ S Belongs to the UPF0354 family
LKLMECAK_00486 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LKLMECAK_00487 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
LKLMECAK_00488 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LKLMECAK_00489 1.7e-51 ytzB S small secreted protein
LKLMECAK_00490 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
LKLMECAK_00491 2.1e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
LKLMECAK_00492 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LKLMECAK_00493 3.5e-45 ytzH S YtzH-like protein
LKLMECAK_00494 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
LKLMECAK_00495 4.4e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LKLMECAK_00496 1.2e-166 ytlQ
LKLMECAK_00497 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LKLMECAK_00498 3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LKLMECAK_00499 4e-267 pepV 3.5.1.18 E Dipeptidase
LKLMECAK_00500 1.3e-227 pbuO S permease
LKLMECAK_00501 4.6e-216 ythQ U Bacterial ABC transporter protein EcsB
LKLMECAK_00502 3.7e-128 ythP V ABC transporter
LKLMECAK_00503 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
LKLMECAK_00504 5.3e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LKLMECAK_00505 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKLMECAK_00506 5.7e-236 ytfP S HI0933-like protein
LKLMECAK_00507 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LKLMECAK_00508 9e-26 yteV S Sporulation protein Cse60
LKLMECAK_00509 4.8e-185 msmR K Transcriptional regulator
LKLMECAK_00510 4.9e-243 msmE G Bacterial extracellular solute-binding protein
LKLMECAK_00511 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
LKLMECAK_00512 4.1e-142 amyC P ABC transporter (permease)
LKLMECAK_00513 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LKLMECAK_00514 1.7e-84 M Acetyltransferase (GNAT) domain
LKLMECAK_00515 5.6e-52 ytwF P Sulfurtransferase
LKLMECAK_00516 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LKLMECAK_00517 1.2e-52 ytvB S Protein of unknown function (DUF4257)
LKLMECAK_00518 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LKLMECAK_00519 2.3e-207 yttB EGP Major facilitator Superfamily
LKLMECAK_00520 1.4e-122 ywaF S Integral membrane protein
LKLMECAK_00521 0.0 bceB V ABC transporter (permease)
LKLMECAK_00522 1.4e-133 bceA V ABC transporter, ATP-binding protein
LKLMECAK_00523 6e-169 T PhoQ Sensor
LKLMECAK_00524 2.8e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKLMECAK_00525 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
LKLMECAK_00526 2.2e-125 ytrE V ABC transporter, ATP-binding protein
LKLMECAK_00527 1.2e-151
LKLMECAK_00528 5.9e-172 P ABC-2 family transporter protein
LKLMECAK_00529 2e-164 S ABC-2 family transporter protein
LKLMECAK_00530 5.5e-161 ytrB P abc transporter atp-binding protein
LKLMECAK_00531 3.9e-66 ytrA K GntR family transcriptional regulator
LKLMECAK_00533 7.4e-40 ytzC S Protein of unknown function (DUF2524)
LKLMECAK_00534 6.8e-193 K helix_turn_helix, Arsenical Resistance Operon Repressor
LKLMECAK_00535 5.3e-282 norB EGP COG0477 Permeases of the major facilitator superfamily
LKLMECAK_00536 1.1e-189 yhcC S Fe-S oxidoreductase
LKLMECAK_00537 2.5e-106 ytqB J Putative rRNA methylase
LKLMECAK_00539 2.6e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
LKLMECAK_00540 7.1e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
LKLMECAK_00541 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
LKLMECAK_00542 6.7e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LKLMECAK_00543 1.1e-259 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
LKLMECAK_00544 0.0 asnB 6.3.5.4 E Asparagine synthase
LKLMECAK_00545 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LKLMECAK_00546 7.7e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LKLMECAK_00547 1.6e-38 ytmB S Protein of unknown function (DUF2584)
LKLMECAK_00548 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LKLMECAK_00549 5.8e-183 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LKLMECAK_00550 3.2e-144 ytlC P ABC transporter
LKLMECAK_00551 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LKLMECAK_00552 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
LKLMECAK_00553 5e-61 ytkC S Bacteriophage holin family
LKLMECAK_00554 1e-75 dps P Belongs to the Dps family
LKLMECAK_00556 7.9e-76 ytkA S YtkA-like
LKLMECAK_00557 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LKLMECAK_00558 1.2e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LKLMECAK_00559 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LKLMECAK_00560 7.9e-41 rpmE2 J Ribosomal protein L31
LKLMECAK_00561 1.5e-239 cydA 1.10.3.14 C oxidase, subunit
LKLMECAK_00562 1.5e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LKLMECAK_00563 2e-23 S Domain of Unknown Function (DUF1540)
LKLMECAK_00564 1.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LKLMECAK_00565 4.1e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LKLMECAK_00566 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LKLMECAK_00567 4.7e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LKLMECAK_00568 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LKLMECAK_00569 6.1e-271 menF 5.4.4.2 HQ Isochorismate synthase
LKLMECAK_00570 7e-130 dksA T COG1734 DnaK suppressor protein
LKLMECAK_00571 6.5e-76 tspO T membrane
LKLMECAK_00580 7.8e-08
LKLMECAK_00581 1.3e-09
LKLMECAK_00588 1.6e-08
LKLMECAK_00593 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_00594 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_00595 3.2e-43 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_00596 0.0 pksJ Q Polyketide synthase of type I
LKLMECAK_00597 0.0 pfaA Q Polyketide synthase of type I
LKLMECAK_00598 0.0 Q Polyketide synthase of type I
LKLMECAK_00599 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LKLMECAK_00600 3.1e-220 eryK 1.14.13.154 C Cytochrome P450
LKLMECAK_00601 6.3e-238 pksG 2.3.3.10 I synthase
LKLMECAK_00602 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
LKLMECAK_00603 2.4e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKLMECAK_00604 3.7e-171 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
LKLMECAK_00605 5.5e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
LKLMECAK_00606 8.2e-249 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
LKLMECAK_00607 5.9e-177 coaA 2.7.1.33 F Pantothenic acid kinase
LKLMECAK_00608 1.2e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKLMECAK_00610 1.7e-185 yueF S transporter activity
LKLMECAK_00612 2.1e-55 S YolD-like protein
LKLMECAK_00613 1.8e-234 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKLMECAK_00614 8.7e-89 yqjY K acetyltransferase
LKLMECAK_00615 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
LKLMECAK_00616 7.6e-172 yqkA K GrpB protein
LKLMECAK_00617 7.7e-61 yqkB S Belongs to the HesB IscA family
LKLMECAK_00618 3.2e-39 yqkC S Protein of unknown function (DUF2552)
LKLMECAK_00619 3.8e-29 yqkD S COG1073 Hydrolases of the alpha beta superfamily
LKLMECAK_00620 2.5e-135 yqkD S COG1073 Hydrolases of the alpha beta superfamily
LKLMECAK_00622 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
LKLMECAK_00624 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
LKLMECAK_00625 4.5e-219 yqxK 3.6.4.12 L DNA helicase
LKLMECAK_00626 1e-57 ansR K Transcriptional regulator
LKLMECAK_00627 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
LKLMECAK_00628 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
LKLMECAK_00629 1.6e-239 mleN C Na H antiporter
LKLMECAK_00630 3.8e-243 mleA 1.1.1.38 C malic enzyme
LKLMECAK_00631 5.7e-22
LKLMECAK_00632 8.6e-34 yqkK
LKLMECAK_00634 2.1e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LKLMECAK_00635 1.9e-80 fur P Belongs to the Fur family
LKLMECAK_00636 3.7e-37 S Protein of unknown function (DUF4227)
LKLMECAK_00637 8.2e-165 xerD L recombinase XerD
LKLMECAK_00638 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LKLMECAK_00639 9.3e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LKLMECAK_00640 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
LKLMECAK_00641 6.6e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
LKLMECAK_00642 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LKLMECAK_00643 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKLMECAK_00644 1.8e-110 spoVAA S Stage V sporulation protein AA
LKLMECAK_00645 5.1e-60 spoVAB S Stage V sporulation protein AB
LKLMECAK_00646 6e-79 spoVAC S stage V sporulation protein AC
LKLMECAK_00647 1.2e-188 spoVAD I Stage V sporulation protein AD
LKLMECAK_00648 5e-57 spoVAEB S stage V sporulation protein
LKLMECAK_00649 5.2e-110 spoVAEA S stage V sporulation protein
LKLMECAK_00650 3.2e-270 spoVAF EG Stage V sporulation protein AF
LKLMECAK_00651 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LKLMECAK_00652 1.9e-153 ypuA S Secreted protein
LKLMECAK_00653 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LKLMECAK_00654 1.2e-80 ccdC1 O Protein of unknown function (DUF1453)
LKLMECAK_00655 5.8e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LKLMECAK_00656 1.4e-48 ypuD
LKLMECAK_00657 1.8e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LKLMECAK_00658 6.5e-111 ribE 2.5.1.9 H Riboflavin synthase
LKLMECAK_00659 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LKLMECAK_00660 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LKLMECAK_00661 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKLMECAK_00662 2.9e-93 ypuF S Domain of unknown function (DUF309)
LKLMECAK_00664 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LKLMECAK_00665 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LKLMECAK_00666 3.8e-93 ypuI S Protein of unknown function (DUF3907)
LKLMECAK_00667 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
LKLMECAK_00668 2e-103 spmA S Spore maturation protein
LKLMECAK_00669 6.4e-88 spmB S Spore maturation protein
LKLMECAK_00670 1.3e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LKLMECAK_00671 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LKLMECAK_00672 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
LKLMECAK_00673 9.4e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LKLMECAK_00674 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKLMECAK_00675 0.0 resE 2.7.13.3 T Histidine kinase
LKLMECAK_00676 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
LKLMECAK_00677 9.7e-192 rsiX
LKLMECAK_00678 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKLMECAK_00679 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LKLMECAK_00680 3.6e-41 fer C Ferredoxin
LKLMECAK_00681 1.1e-192 ypbB 5.1.3.1 S protein conserved in bacteria
LKLMECAK_00682 1.5e-269 recQ 3.6.4.12 L DNA helicase
LKLMECAK_00683 4e-99 ypbD S metal-dependent membrane protease
LKLMECAK_00684 5.4e-72 ypbE M Lysin motif
LKLMECAK_00685 5.7e-85 ypbF S Protein of unknown function (DUF2663)
LKLMECAK_00686 7.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
LKLMECAK_00687 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LKLMECAK_00688 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LKLMECAK_00689 3.4e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
LKLMECAK_00690 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
LKLMECAK_00691 3e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
LKLMECAK_00692 4.6e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
LKLMECAK_00693 1.4e-60 ypfA M Flagellar protein YcgR
LKLMECAK_00694 1.4e-12 S Family of unknown function (DUF5359)
LKLMECAK_00695 1e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LKLMECAK_00696 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
LKLMECAK_00697 5e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LKLMECAK_00698 4.7e-08 S YpzI-like protein
LKLMECAK_00699 7.2e-104 yphA
LKLMECAK_00700 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LKLMECAK_00701 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LKLMECAK_00702 9.5e-16 yphE S Protein of unknown function (DUF2768)
LKLMECAK_00703 1.1e-133 yphF
LKLMECAK_00704 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LKLMECAK_00705 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LKLMECAK_00706 2.1e-100 folE 3.5.4.16 H GTP cyclohydrolase
LKLMECAK_00707 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LKLMECAK_00708 1.8e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LKLMECAK_00709 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LKLMECAK_00710 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LKLMECAK_00711 5e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LKLMECAK_00712 1.1e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
LKLMECAK_00713 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LKLMECAK_00714 3.2e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LKLMECAK_00715 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LKLMECAK_00716 2.7e-288 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LKLMECAK_00717 8.3e-153 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LKLMECAK_00718 3.6e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LKLMECAK_00719 1.7e-114 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
LKLMECAK_00720 2.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LKLMECAK_00721 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LKLMECAK_00722 1.9e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LKLMECAK_00723 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LKLMECAK_00724 8.1e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LKLMECAK_00725 3.5e-233 S COG0457 FOG TPR repeat
LKLMECAK_00726 2.1e-99 ypiB S Belongs to the UPF0302 family
LKLMECAK_00727 3.2e-77 ypiF S Protein of unknown function (DUF2487)
LKLMECAK_00728 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
LKLMECAK_00729 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
LKLMECAK_00730 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
LKLMECAK_00731 2.9e-105 ypjA S membrane
LKLMECAK_00732 9.5e-141 ypjB S sporulation protein
LKLMECAK_00733 2.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
LKLMECAK_00734 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
LKLMECAK_00735 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
LKLMECAK_00736 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LKLMECAK_00737 1.2e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
LKLMECAK_00738 1.9e-132 bshB1 S proteins, LmbE homologs
LKLMECAK_00739 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
LKLMECAK_00740 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LKLMECAK_00741 6.2e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LKLMECAK_00742 1.7e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LKLMECAK_00743 2.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LKLMECAK_00744 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LKLMECAK_00745 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LKLMECAK_00746 6.7e-23 ypmA S Protein of unknown function (DUF4264)
LKLMECAK_00747 1.5e-80 ypmB S protein conserved in bacteria
LKLMECAK_00748 4.1e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LKLMECAK_00749 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
LKLMECAK_00750 3e-130 dnaD L DNA replication protein DnaD
LKLMECAK_00751 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LKLMECAK_00752 5.7e-91 ypoC
LKLMECAK_00753 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LKLMECAK_00754 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LKLMECAK_00755 2.6e-188 yppC S Protein of unknown function (DUF2515)
LKLMECAK_00758 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
LKLMECAK_00760 2.1e-49 yppG S YppG-like protein
LKLMECAK_00761 7.9e-70 hspX O Belongs to the small heat shock protein (HSP20) family
LKLMECAK_00762 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
LKLMECAK_00763 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LKLMECAK_00764 8e-235 yprB L RNase_H superfamily
LKLMECAK_00766 9.9e-33 cotD S Inner spore coat protein D
LKLMECAK_00767 1.1e-98 ypsA S Belongs to the UPF0398 family
LKLMECAK_00768 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LKLMECAK_00769 5.1e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LKLMECAK_00770 6.6e-22 S YpzG-like protein
LKLMECAK_00772 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
LKLMECAK_00773 4.8e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LKLMECAK_00774 6.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LKLMECAK_00775 2.9e-64 pbuX F xanthine
LKLMECAK_00776 4e-50 L Recombinase
LKLMECAK_00777 1.4e-77 yokF 3.1.31.1 L RNA catabolic process
LKLMECAK_00778 1.5e-92 G SMI1-KNR4 cell-wall
LKLMECAK_00779 2e-167 V HNH endonuclease
LKLMECAK_00780 7.4e-218 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LKLMECAK_00781 7.8e-97 yokK S SMI1 / KNR4 family
LKLMECAK_00783 4.8e-129 yunB S Sporulation protein YunB (Spo_YunB)
LKLMECAK_00784 5.3e-40 S YolD-like protein
LKLMECAK_00785 3.2e-223 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKLMECAK_00787 7.4e-89 S response regulator aspartate phosphatase
LKLMECAK_00790 3.1e-32 S Bacteriophage holin
LKLMECAK_00792 8.4e-76 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LKLMECAK_00793 2.1e-266 M Pectate lyase superfamily protein
LKLMECAK_00794 9.1e-94
LKLMECAK_00795 0.0 S Pfam Transposase IS66
LKLMECAK_00796 1.9e-125 S Phage tail protein
LKLMECAK_00797 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LKLMECAK_00798 3.8e-77
LKLMECAK_00800 3e-67 S DNA integration
LKLMECAK_00801 4.6e-49
LKLMECAK_00802 1.1e-57
LKLMECAK_00804 5.9e-74
LKLMECAK_00805 3.9e-49
LKLMECAK_00807 7.1e-91
LKLMECAK_00808 2.6e-89
LKLMECAK_00809 1.3e-85
LKLMECAK_00810 1.8e-55
LKLMECAK_00813 4e-68
LKLMECAK_00815 6.3e-40
LKLMECAK_00816 8.2e-19
LKLMECAK_00817 1.8e-94
LKLMECAK_00818 1.7e-17
LKLMECAK_00821 1e-218 S Calcineurin-like phosphoesterase superfamily domain
LKLMECAK_00825 1e-33 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LKLMECAK_00826 0.0
LKLMECAK_00830 6.4e-58 ftsZ D Tubulin/FtsZ family, GTPase domain
LKLMECAK_00832 1.2e-214
LKLMECAK_00834 8.6e-197 3.1.21.3 L Domain of unknown function (DUF4942)
LKLMECAK_00838 4.5e-17
LKLMECAK_00839 4.4e-09
LKLMECAK_00841 6.2e-21 I Acyltransferase family
LKLMECAK_00842 5.4e-69 yoaW
LKLMECAK_00843 8e-23 K Cro/C1-type HTH DNA-binding domain
LKLMECAK_00853 5e-40 S HicB_like antitoxin of bacterial toxin-antitoxin system
LKLMECAK_00854 2.2e-77
LKLMECAK_00860 1.2e-37 L Belongs to the 'phage' integrase family
LKLMECAK_00861 5.8e-186
LKLMECAK_00862 4.9e-33
LKLMECAK_00863 2.4e-12 K Transcriptional regulator
LKLMECAK_00867 2.1e-42
LKLMECAK_00868 5.6e-07 S YopX protein
LKLMECAK_00871 5.8e-265 3.1.3.16, 3.1.4.37 T phosphatase
LKLMECAK_00875 1.1e-84 S Protein of unknown function (DUF1273)
LKLMECAK_00881 5.2e-74
LKLMECAK_00883 1.2e-51 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
LKLMECAK_00886 6.4e-64
LKLMECAK_00888 3.9e-137 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
LKLMECAK_00889 6.3e-125 yoqW S Belongs to the SOS response-associated peptidase family
LKLMECAK_00892 8.2e-10 S YopX protein
LKLMECAK_00893 8.8e-159
LKLMECAK_00895 2.9e-33 S YopX protein
LKLMECAK_00897 1.1e-89 S Pfam:DUF867
LKLMECAK_00898 3e-219 M Parallel beta-helix repeats
LKLMECAK_00902 1.4e-170
LKLMECAK_00903 8.5e-159 S AAA domain
LKLMECAK_00905 1.4e-241 3.6.4.12 L DnaB-like helicase C terminal domain
LKLMECAK_00906 5.2e-147 3.6.4.12 L DNA primase activity
LKLMECAK_00907 1.1e-171 S PD-(D/E)XK nuclease superfamily
LKLMECAK_00908 5.8e-292 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
LKLMECAK_00909 1.2e-23 DR0488 S protein conserved in bacteria
LKLMECAK_00912 1e-69 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
LKLMECAK_00913 2.5e-89 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
LKLMECAK_00939 1.1e-54 S NrdI Flavodoxin like
LKLMECAK_00940 0.0 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
LKLMECAK_00942 7.5e-175 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKLMECAK_00943 5.3e-26 O Glutaredoxin
LKLMECAK_00944 9.1e-54 ymaB S MutT family
LKLMECAK_00949 2.2e-151 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LKLMECAK_00950 1.1e-28 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LKLMECAK_00954 5.7e-10
LKLMECAK_00956 4.9e-23 sspB S spore protein
LKLMECAK_00957 8.3e-151 S Calcineurin-like phosphoesterase
LKLMECAK_00965 7.1e-90 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LKLMECAK_00967 4e-159 pbuX F xanthine
LKLMECAK_00969 1.6e-97 yrdC 3.5.1.19 Q Isochorismatase family
LKLMECAK_00970 6.3e-28 ydfR S Protein of unknown function (DUF421)
LKLMECAK_00971 3.9e-22 ydfR S Protein of unknown function (DUF421)
LKLMECAK_00973 1.5e-49 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
LKLMECAK_00974 1.6e-106 J Acetyltransferase (GNAT) domain
LKLMECAK_00975 1.9e-203 bcsA Q Naringenin-chalcone synthase
LKLMECAK_00976 2.7e-88 ypbQ S protein conserved in bacteria
LKLMECAK_00977 0.0 ypbR S Dynamin family
LKLMECAK_00978 2.2e-38 ypbS S Protein of unknown function (DUF2533)
LKLMECAK_00980 5.9e-163 polA 2.7.7.7 L 5'3' exonuclease
LKLMECAK_00982 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
LKLMECAK_00983 2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LKLMECAK_00984 9.1e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
LKLMECAK_00985 1.5e-28 ypeQ S Zinc-finger
LKLMECAK_00986 6.1e-36 S Protein of unknown function (DUF2564)
LKLMECAK_00987 1.3e-11 degR
LKLMECAK_00988 1e-30 cspD K Cold-shock protein
LKLMECAK_00989 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LKLMECAK_00990 3.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LKLMECAK_00991 7.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LKLMECAK_00992 3.1e-99 ypgQ S phosphohydrolase
LKLMECAK_00993 4.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
LKLMECAK_00994 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LKLMECAK_00995 1e-75 yphP S Belongs to the UPF0403 family
LKLMECAK_00996 1.1e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
LKLMECAK_00997 8.5e-113 ypjP S YpjP-like protein
LKLMECAK_00998 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LKLMECAK_00999 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LKLMECAK_01000 6.1e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LKLMECAK_01001 3.5e-109 hlyIII S protein, Hemolysin III
LKLMECAK_01002 1.6e-172 pspF K Transcriptional regulator
LKLMECAK_01003 6.3e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LKLMECAK_01004 1.4e-37 ypmP S Protein of unknown function (DUF2535)
LKLMECAK_01005 3.6e-114 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LKLMECAK_01006 6.4e-134 ypmR E GDSL-like Lipase/Acylhydrolase
LKLMECAK_01007 6.1e-97 ypmS S protein conserved in bacteria
LKLMECAK_01008 1.4e-66 ypoP K transcriptional
LKLMECAK_01009 2.7e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LKLMECAK_01010 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LKLMECAK_01011 2.6e-103 4.2.1.115 GM Polysaccharide biosynthesis protein
LKLMECAK_01012 1.2e-302 yokA L Recombinase
LKLMECAK_01014 1.7e-47 yokH G SMI1 / KNR4 family
LKLMECAK_01015 2.4e-26 yokH G SMI1 / KNR4 family
LKLMECAK_01016 4.1e-288 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LKLMECAK_01017 7.5e-53 S SMI1-KNR4 cell-wall
LKLMECAK_01018 4.9e-89 yokK S SMI1 / KNR4 family
LKLMECAK_01019 6.6e-30 S Acetyltransferase (GNAT) domain
LKLMECAK_01020 7e-24
LKLMECAK_01021 2.6e-08 S Domain of unknown function (DUF4879)
LKLMECAK_01023 7.2e-157 3.4.24.40 S amine dehydrogenase activity
LKLMECAK_01026 1.9e-206 S aspartate phosphatase
LKLMECAK_01027 5.3e-75 yoqH M LysM domain
LKLMECAK_01030 2.6e-08
LKLMECAK_01031 2.5e-22 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
LKLMECAK_01032 1.7e-77
LKLMECAK_01038 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
LKLMECAK_01039 2.6e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
LKLMECAK_01040 1.4e-178 cgeB S Spore maturation protein
LKLMECAK_01041 1.6e-52 cgeA
LKLMECAK_01042 1.2e-40 cgeC
LKLMECAK_01043 1.2e-241 cgeD M maturation of the outermost layer of the spore
LKLMECAK_01044 1.4e-144 yiiD K acetyltransferase
LKLMECAK_01046 3.2e-64 yosT L Bacterial transcription activator, effector binding domain
LKLMECAK_01047 1.9e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKLMECAK_01048 2.9e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LKLMECAK_01049 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LKLMECAK_01050 9e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
LKLMECAK_01051 9.8e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
LKLMECAK_01052 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
LKLMECAK_01053 9.2e-46 yokU S YokU-like protein, putative antitoxin
LKLMECAK_01054 9.1e-36 yozE S Belongs to the UPF0346 family
LKLMECAK_01055 2.6e-24 E lactoylglutathione lyase activity
LKLMECAK_01056 1.7e-125 yodN
LKLMECAK_01058 6.2e-24 yozD S YozD-like protein
LKLMECAK_01059 1.4e-102 yodM 3.6.1.27 I Acid phosphatase homologues
LKLMECAK_01060 3.3e-55 yodL S YodL-like
LKLMECAK_01062 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
LKLMECAK_01063 2.3e-121 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LKLMECAK_01064 1.9e-21 yodI
LKLMECAK_01065 2.8e-128 yodH Q Methyltransferase
LKLMECAK_01066 7.9e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
LKLMECAK_01067 2.6e-132 yydK K Transcriptional regulator
LKLMECAK_01068 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LKLMECAK_01069 1e-276 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
LKLMECAK_01070 3e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKLMECAK_01071 1.4e-19 S Protein of unknown function (DUF3311)
LKLMECAK_01072 5e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
LKLMECAK_01073 5.7e-109 mhqD S Carboxylesterase
LKLMECAK_01074 4.5e-106 yodC C nitroreductase
LKLMECAK_01075 3e-56 yodB K transcriptional
LKLMECAK_01076 3.9e-68 yoaQ S Evidence 4 Homologs of previously reported genes of
LKLMECAK_01077 2.3e-66 yodA S tautomerase
LKLMECAK_01079 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
LKLMECAK_01080 1.1e-161 rarD S -transporter
LKLMECAK_01081 4.9e-23
LKLMECAK_01082 3.7e-60 yojF S Protein of unknown function (DUF1806)
LKLMECAK_01083 5.6e-126 yojG S deacetylase
LKLMECAK_01084 2.2e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKLMECAK_01085 6.1e-236 norM V Multidrug efflux pump
LKLMECAK_01087 1.7e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LKLMECAK_01088 6.9e-223 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
LKLMECAK_01089 5.2e-226 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LKLMECAK_01090 8.9e-99 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LKLMECAK_01091 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
LKLMECAK_01092 0.0 yojO P Von Willebrand factor
LKLMECAK_01093 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LKLMECAK_01094 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LKLMECAK_01095 7.2e-138 S Metallo-beta-lactamase superfamily
LKLMECAK_01096 3e-160 yocS S -transporter
LKLMECAK_01097 8.7e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LKLMECAK_01098 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
LKLMECAK_01099 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
LKLMECAK_01100 9.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
LKLMECAK_01101 3.6e-31 yozC
LKLMECAK_01103 2.4e-56 yozO S Bacterial PH domain
LKLMECAK_01104 8.5e-37 yocN
LKLMECAK_01105 3.8e-44 yozN
LKLMECAK_01106 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
LKLMECAK_01107 7.5e-09
LKLMECAK_01108 1e-09 yocL
LKLMECAK_01109 8.6e-55 dksA T general stress protein
LKLMECAK_01111 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LKLMECAK_01112 0.0 recQ 3.6.4.12 L DNA helicase
LKLMECAK_01113 3.1e-108 yocH CBM50 M COG1388 FOG LysM repeat
LKLMECAK_01115 5.5e-186 yocD 3.4.17.13 V peptidase S66
LKLMECAK_01116 1.6e-93 yocC
LKLMECAK_01117 1.2e-138 yocB J Protein required for attachment to host cells
LKLMECAK_01118 3.6e-91 yozB S membrane
LKLMECAK_01119 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LKLMECAK_01120 8.4e-54 czrA K transcriptional
LKLMECAK_01121 7.1e-92 yobW
LKLMECAK_01122 7.2e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
LKLMECAK_01123 3.4e-92 yobS K Transcriptional regulator
LKLMECAK_01124 4.3e-132 yobQ K helix_turn_helix, arabinose operon control protein
LKLMECAK_01125 1.1e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
LKLMECAK_01126 3.8e-60 ykvN K HxlR-like helix-turn-helix
LKLMECAK_01127 1.9e-130 IQ Enoyl-(Acyl carrier protein) reductase
LKLMECAK_01128 6.7e-44
LKLMECAK_01129 1.5e-95 hpr K helix_turn_helix multiple antibiotic resistance protein
LKLMECAK_01130 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKLMECAK_01131 5.3e-192 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKLMECAK_01132 1.5e-267 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
LKLMECAK_01133 7.4e-204 yoaB EGP Major facilitator Superfamily
LKLMECAK_01134 2.3e-131 yoxB
LKLMECAK_01135 2.4e-39 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LKLMECAK_01136 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LKLMECAK_01137 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LKLMECAK_01138 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKLMECAK_01139 6.2e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LKLMECAK_01140 4.5e-150 gltC K Transcriptional regulator
LKLMECAK_01141 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
LKLMECAK_01142 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LKLMECAK_01143 4.8e-182 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LKLMECAK_01144 1.2e-152 gltR1 K Transcriptional regulator
LKLMECAK_01145 1.5e-14 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LKLMECAK_01146 1.8e-50 ybzH K Helix-turn-helix domain
LKLMECAK_01147 5.2e-199 ybcL EGP Major facilitator Superfamily
LKLMECAK_01148 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LKLMECAK_01149 1.8e-34 yoeD G Helix-turn-helix domain
LKLMECAK_01150 3.5e-97 L Integrase
LKLMECAK_01152 1e-96 yoeB S IseA DL-endopeptidase inhibitor
LKLMECAK_01153 6.7e-246 yoeA V MATE efflux family protein
LKLMECAK_01154 1.3e-184 yoxA 5.1.3.3 G Aldose 1-epimerase
LKLMECAK_01155 1.5e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
LKLMECAK_01156 6.8e-69 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_01157 1.1e-52 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_01158 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_01159 7.5e-77 ctsR K Belongs to the CtsR family
LKLMECAK_01160 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
LKLMECAK_01161 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LKLMECAK_01162 0.0 clpC O Belongs to the ClpA ClpB family
LKLMECAK_01163 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LKLMECAK_01164 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LKLMECAK_01165 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
LKLMECAK_01166 4.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LKLMECAK_01167 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LKLMECAK_01168 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LKLMECAK_01169 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
LKLMECAK_01170 5.3e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LKLMECAK_01171 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LKLMECAK_01172 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKLMECAK_01173 4.2e-89 yacP S RNA-binding protein containing a PIN domain
LKLMECAK_01174 8.9e-116 sigH K Belongs to the sigma-70 factor family
LKLMECAK_01175 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LKLMECAK_01176 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
LKLMECAK_01177 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LKLMECAK_01178 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LKLMECAK_01179 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LKLMECAK_01180 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LKLMECAK_01181 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
LKLMECAK_01182 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKLMECAK_01183 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKLMECAK_01184 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
LKLMECAK_01185 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LKLMECAK_01186 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LKLMECAK_01187 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LKLMECAK_01188 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LKLMECAK_01189 1.2e-182 ybaC 3.4.11.5 S Alpha/beta hydrolase family
LKLMECAK_01190 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LKLMECAK_01191 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LKLMECAK_01192 3e-105 rplD J Forms part of the polypeptide exit tunnel
LKLMECAK_01193 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LKLMECAK_01194 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LKLMECAK_01195 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LKLMECAK_01196 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LKLMECAK_01197 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LKLMECAK_01198 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LKLMECAK_01199 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
LKLMECAK_01200 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LKLMECAK_01201 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LKLMECAK_01202 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LKLMECAK_01203 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LKLMECAK_01204 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKLMECAK_01205 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LKLMECAK_01206 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LKLMECAK_01207 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LKLMECAK_01208 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LKLMECAK_01209 1.9e-23 rpmD J Ribosomal protein L30
LKLMECAK_01210 4.1e-72 rplO J binds to the 23S rRNA
LKLMECAK_01211 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LKLMECAK_01212 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LKLMECAK_01213 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
LKLMECAK_01214 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LKLMECAK_01215 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LKLMECAK_01216 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LKLMECAK_01217 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LKLMECAK_01218 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKLMECAK_01219 4.7e-58 rplQ J Ribosomal protein L17
LKLMECAK_01220 2.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKLMECAK_01221 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKLMECAK_01222 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKLMECAK_01223 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LKLMECAK_01224 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LKLMECAK_01225 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
LKLMECAK_01226 2.9e-142 ybaJ Q Methyltransferase domain
LKLMECAK_01227 1.2e-82 yizA S Damage-inducible protein DinB
LKLMECAK_01228 4.2e-77 ybaK S Protein of unknown function (DUF2521)
LKLMECAK_01229 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKLMECAK_01230 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LKLMECAK_01231 1.7e-75 gerD
LKLMECAK_01232 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
LKLMECAK_01233 2.1e-132 pdaB 3.5.1.104 G Polysaccharide deacetylase
LKLMECAK_01234 3.4e-39 S COG NOG14552 non supervised orthologous group
LKLMECAK_01235 1.5e-95 thiT S Thiamine transporter protein (Thia_YuaJ)
LKLMECAK_01236 1.7e-178 yuaG 3.4.21.72 S protein conserved in bacteria
LKLMECAK_01237 4.7e-83 yuaF OU Membrane protein implicated in regulation of membrane protease activity
LKLMECAK_01238 2e-72 yuaE S DinB superfamily
LKLMECAK_01239 2.7e-108 yuaD S MOSC domain
LKLMECAK_01240 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
LKLMECAK_01241 1.6e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
LKLMECAK_01242 8.6e-96 yuaC K Belongs to the GbsR family
LKLMECAK_01243 7.9e-94 yuaB
LKLMECAK_01244 3.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
LKLMECAK_01245 1.5e-144 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKLMECAK_01246 1.6e-216 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LKLMECAK_01247 1.4e-118 G Cupin
LKLMECAK_01248 2.4e-50 yjcN
LKLMECAK_01250 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LKLMECAK_01251 2.9e-194 yubA S transporter activity
LKLMECAK_01252 1.4e-184 ygjR S Oxidoreductase
LKLMECAK_01253 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
LKLMECAK_01254 1.3e-234 mcpA NT chemotaxis protein
LKLMECAK_01255 6e-224 mcpA NT chemotaxis protein
LKLMECAK_01256 1.5e-235 mcpA NT chemotaxis protein
LKLMECAK_01257 8.1e-221 mcpA NT chemotaxis protein
LKLMECAK_01258 2.2e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
LKLMECAK_01259 1.4e-40
LKLMECAK_01260 5.6e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LKLMECAK_01261 2e-73 yugU S Uncharacterised protein family UPF0047
LKLMECAK_01262 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
LKLMECAK_01263 2.5e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
LKLMECAK_01264 8.3e-117 yugP S Zn-dependent protease
LKLMECAK_01265 3.4e-18
LKLMECAK_01266 6.7e-27 mstX S Membrane-integrating protein Mistic
LKLMECAK_01267 5.3e-181 yugO P COG1226 Kef-type K transport systems
LKLMECAK_01268 7e-71 yugN S YugN-like family
LKLMECAK_01270 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
LKLMECAK_01271 3.6e-45 S NADPH-dependent FMN reductase
LKLMECAK_01272 3.5e-117 ycaC Q Isochorismatase family
LKLMECAK_01273 1.8e-228 yugK C Dehydrogenase
LKLMECAK_01274 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
LKLMECAK_01275 1.8e-34 yuzA S Domain of unknown function (DUF378)
LKLMECAK_01276 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
LKLMECAK_01277 1.6e-208 yugH 2.6.1.1 E Aminotransferase
LKLMECAK_01278 2e-83 alaR K Transcriptional regulator
LKLMECAK_01279 5.5e-155 yugF I Hydrolase
LKLMECAK_01280 1.4e-40 yugE S Domain of unknown function (DUF1871)
LKLMECAK_01281 3.3e-222 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LKLMECAK_01282 8.9e-229 T PhoQ Sensor
LKLMECAK_01283 7.7e-67 kapB G Kinase associated protein B
LKLMECAK_01284 4e-118 kapD L the KinA pathway to sporulation
LKLMECAK_01285 4.5e-185 yuxJ EGP Major facilitator Superfamily
LKLMECAK_01286 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
LKLMECAK_01287 2.2e-72 yuxK S protein conserved in bacteria
LKLMECAK_01288 2.7e-73 yufK S Family of unknown function (DUF5366)
LKLMECAK_01289 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LKLMECAK_01290 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
LKLMECAK_01291 1.7e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
LKLMECAK_01292 2.8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LKLMECAK_01293 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
LKLMECAK_01294 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
LKLMECAK_01295 2.3e-12
LKLMECAK_01296 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LKLMECAK_01297 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKLMECAK_01298 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKLMECAK_01299 4.5e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKLMECAK_01300 8.5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKLMECAK_01301 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKLMECAK_01302 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
LKLMECAK_01303 1.1e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
LKLMECAK_01304 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKLMECAK_01305 5.3e-256 comP 2.7.13.3 T Histidine kinase
LKLMECAK_01307 4.4e-62 comQ H Polyprenyl synthetase
LKLMECAK_01310 1.2e-50 yuzC
LKLMECAK_01311 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
LKLMECAK_01312 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LKLMECAK_01313 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
LKLMECAK_01314 7.2e-68 yueI S Protein of unknown function (DUF1694)
LKLMECAK_01315 2.8e-38 yueH S YueH-like protein
LKLMECAK_01316 6.4e-34 yueG S Spore germination protein gerPA/gerPF
LKLMECAK_01317 3.6e-186 yueF S transporter activity
LKLMECAK_01318 1.6e-22 S Protein of unknown function (DUF2642)
LKLMECAK_01319 8.3e-96 yueE S phosphohydrolase
LKLMECAK_01320 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKLMECAK_01321 1.3e-76 yueC S Family of unknown function (DUF5383)
LKLMECAK_01322 0.0 esaA S type VII secretion protein EsaA
LKLMECAK_01323 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LKLMECAK_01324 1.2e-204 essB S WXG100 protein secretion system (Wss), protein YukC
LKLMECAK_01325 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
LKLMECAK_01326 3.3e-46 esxA S Belongs to the WXG100 family
LKLMECAK_01327 4.2e-228 yukF QT Transcriptional regulator
LKLMECAK_01328 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
LKLMECAK_01329 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
LKLMECAK_01330 1.1e-33 mbtH S MbtH-like protein
LKLMECAK_01331 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_01332 3.6e-171 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
LKLMECAK_01333 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
LKLMECAK_01334 1.9e-220 entC 5.4.4.2 HQ Isochorismate synthase
LKLMECAK_01335 4.8e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKLMECAK_01336 1.5e-163 besA S Putative esterase
LKLMECAK_01337 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
LKLMECAK_01338 5.6e-101 bioY S Biotin biosynthesis protein
LKLMECAK_01339 1.2e-207 yuiF S antiporter
LKLMECAK_01340 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LKLMECAK_01341 1.6e-77 yuiD S protein conserved in bacteria
LKLMECAK_01342 2.7e-117 yuiC S protein conserved in bacteria
LKLMECAK_01343 9.9e-28 yuiB S Putative membrane protein
LKLMECAK_01344 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
LKLMECAK_01345 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
LKLMECAK_01347 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LKLMECAK_01348 4.8e-29
LKLMECAK_01349 1e-69 CP Membrane
LKLMECAK_01350 1.5e-121 V ABC transporter
LKLMECAK_01352 2.2e-33 S Bacteriocin class IId cyclical uberolysin-like
LKLMECAK_01354 3.9e-26 K helix_turn_helix, mercury resistance
LKLMECAK_01355 2.4e-136 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
LKLMECAK_01356 1.1e-62 erpA S Belongs to the HesB IscA family
LKLMECAK_01357 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LKLMECAK_01358 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKLMECAK_01359 2.4e-39 yuzB S Belongs to the UPF0349 family
LKLMECAK_01360 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
LKLMECAK_01361 1.1e-53 yuzD S protein conserved in bacteria
LKLMECAK_01362 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
LKLMECAK_01363 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
LKLMECAK_01364 9.8e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LKLMECAK_01365 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LKLMECAK_01366 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
LKLMECAK_01367 3e-195 yutH S Spore coat protein
LKLMECAK_01368 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LKLMECAK_01369 1.4e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LKLMECAK_01370 6.8e-72 yutE S Protein of unknown function DUF86
LKLMECAK_01371 1.7e-47 yutD S protein conserved in bacteria
LKLMECAK_01372 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LKLMECAK_01373 6.6e-192 lytH M Peptidase, M23
LKLMECAK_01374 3.3e-130 yunB S Sporulation protein YunB (Spo_YunB)
LKLMECAK_01375 6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LKLMECAK_01376 1.1e-144 yunE S membrane transporter protein
LKLMECAK_01377 1.2e-168 yunF S Protein of unknown function DUF72
LKLMECAK_01378 1.1e-59 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
LKLMECAK_01379 4.7e-260 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LKLMECAK_01380 2.2e-301 pucR QT COG2508 Regulator of polyketide synthase expression
LKLMECAK_01382 3.2e-08 S Phage Mu protein F like protein
LKLMECAK_01384 1.9e-212 blt EGP Major facilitator Superfamily
LKLMECAK_01385 1.3e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LKLMECAK_01386 5.2e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LKLMECAK_01387 1.6e-165 bsn L Ribonuclease
LKLMECAK_01388 2e-205 msmX P Belongs to the ABC transporter superfamily
LKLMECAK_01389 3.6e-134 yurK K UTRA
LKLMECAK_01390 9e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
LKLMECAK_01391 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
LKLMECAK_01392 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
LKLMECAK_01393 1.4e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
LKLMECAK_01394 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LKLMECAK_01395 5e-165 K helix_turn_helix, mercury resistance
LKLMECAK_01397 7e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
LKLMECAK_01398 3.1e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
LKLMECAK_01399 1.7e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LKLMECAK_01400 8.7e-270 sufB O FeS cluster assembly
LKLMECAK_01401 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
LKLMECAK_01402 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LKLMECAK_01403 1.2e-244 sufD O assembly protein SufD
LKLMECAK_01404 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LKLMECAK_01405 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LKLMECAK_01406 3e-145 metQ P Belongs to the NlpA lipoprotein family
LKLMECAK_01407 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
LKLMECAK_01408 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LKLMECAK_01409 1.5e-56 yusD S SCP-2 sterol transfer family
LKLMECAK_01410 1.6e-54 yusE CO Thioredoxin
LKLMECAK_01411 4.9e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
LKLMECAK_01412 3.7e-40 yusG S Protein of unknown function (DUF2553)
LKLMECAK_01413 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LKLMECAK_01414 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
LKLMECAK_01415 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
LKLMECAK_01416 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
LKLMECAK_01417 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
LKLMECAK_01418 1.4e-164 fadM E Proline dehydrogenase
LKLMECAK_01419 8.9e-210 yusP P Major facilitator superfamily
LKLMECAK_01420 5.7e-42
LKLMECAK_01421 1.1e-53 yusN M Coat F domain
LKLMECAK_01422 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
LKLMECAK_01423 8.1e-288 yusP P Major facilitator superfamily
LKLMECAK_01424 1e-154 ywbI2 K Transcriptional regulator
LKLMECAK_01425 4.2e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
LKLMECAK_01426 2.4e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKLMECAK_01427 3.3e-39 yusU S Protein of unknown function (DUF2573)
LKLMECAK_01428 3.1e-150 yusV 3.6.3.34 HP ABC transporter
LKLMECAK_01429 3.2e-45 S YusW-like protein
LKLMECAK_01430 0.0 pepF2 E COG1164 Oligoendopeptidase F
LKLMECAK_01431 1.1e-147 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKLMECAK_01432 4.7e-79 dps P Belongs to the Dps family
LKLMECAK_01433 3.8e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKLMECAK_01434 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKLMECAK_01435 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
LKLMECAK_01436 3.4e-24
LKLMECAK_01437 3.2e-156 yuxN K Transcriptional regulator
LKLMECAK_01438 1.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LKLMECAK_01439 6.6e-24 S Protein of unknown function (DUF3970)
LKLMECAK_01440 3.5e-258 gerAA EG Spore germination protein
LKLMECAK_01441 3.6e-186 gerAB E Spore germination protein
LKLMECAK_01442 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
LKLMECAK_01443 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKLMECAK_01444 8.7e-193 vraS 2.7.13.3 T Histidine kinase
LKLMECAK_01445 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
LKLMECAK_01446 7.4e-126 liaG S Putative adhesin
LKLMECAK_01447 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LKLMECAK_01448 5.3e-44 liaI S membrane
LKLMECAK_01449 1.8e-226 yvqJ EGP Major facilitator Superfamily
LKLMECAK_01450 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
LKLMECAK_01451 2.3e-218 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LKLMECAK_01452 5.8e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKLMECAK_01453 4.6e-166 yvrC P ABC transporter substrate-binding protein
LKLMECAK_01454 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKLMECAK_01455 4.2e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
LKLMECAK_01456 0.0 T PhoQ Sensor
LKLMECAK_01457 2.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKLMECAK_01458 1.1e-36
LKLMECAK_01459 3.8e-102 yvrI K RNA polymerase
LKLMECAK_01460 1.6e-15 S YvrJ protein family
LKLMECAK_01461 3e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
LKLMECAK_01462 9.3e-66 yvrL S Regulatory protein YrvL
LKLMECAK_01463 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
LKLMECAK_01464 7.6e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKLMECAK_01465 1.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKLMECAK_01466 2.6e-177 fhuD P ABC transporter
LKLMECAK_01467 1.6e-126 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LKLMECAK_01468 7e-235 yvsH E Arginine ornithine antiporter
LKLMECAK_01469 5.2e-13 S Small spore protein J (Spore_SspJ)
LKLMECAK_01470 1.7e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
LKLMECAK_01471 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LKLMECAK_01472 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
LKLMECAK_01473 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
LKLMECAK_01474 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
LKLMECAK_01475 8.6e-114 yfiK K Regulator
LKLMECAK_01476 1.6e-178 T Histidine kinase
LKLMECAK_01477 2.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
LKLMECAK_01478 1.3e-191 yfiM V ABC-2 type transporter
LKLMECAK_01479 7e-193 yfiN V COG0842 ABC-type multidrug transport system, permease component
LKLMECAK_01480 5e-156 yvgN S reductase
LKLMECAK_01481 2.7e-85 yvgO
LKLMECAK_01482 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
LKLMECAK_01483 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LKLMECAK_01484 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LKLMECAK_01485 0.0 helD 3.6.4.12 L DNA helicase
LKLMECAK_01486 2.9e-97 yvgT S membrane
LKLMECAK_01487 1.7e-140 S Metallo-peptidase family M12
LKLMECAK_01488 5.6e-71 bdbC O Required for disulfide bond formation in some proteins
LKLMECAK_01489 7.5e-102 bdbD O Thioredoxin
LKLMECAK_01490 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LKLMECAK_01491 0.0 copA 3.6.3.54 P P-type ATPase
LKLMECAK_01492 7.6e-29 copZ P Heavy-metal-associated domain
LKLMECAK_01493 1.4e-47 csoR S transcriptional
LKLMECAK_01494 4.6e-191 yvaA 1.1.1.371 S Oxidoreductase
LKLMECAK_01495 2.5e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LKLMECAK_01496 2e-252 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKLMECAK_01497 2.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
LKLMECAK_01498 2.1e-180 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKLMECAK_01499 3.6e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LKLMECAK_01500 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
LKLMECAK_01501 1.7e-120 tcyL P Binding-protein-dependent transport system inner membrane component
LKLMECAK_01502 4.3e-144 tcyK M Bacterial periplasmic substrate-binding proteins
LKLMECAK_01503 4.3e-128 ytmJ ET Bacterial periplasmic substrate-binding proteins
LKLMECAK_01504 3e-101 ytmI K Acetyltransferase (GNAT) domain
LKLMECAK_01505 2.5e-161 ytlI K LysR substrate binding domain
LKLMECAK_01506 6.9e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKLMECAK_01507 3.7e-48 yrdF K ribonuclease inhibitor
LKLMECAK_01509 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LKLMECAK_01510 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LKLMECAK_01511 1.6e-142 est 3.1.1.1 S Carboxylesterase
LKLMECAK_01512 4.8e-24 secG U Preprotein translocase subunit SecG
LKLMECAK_01513 6e-35 yvzC K Transcriptional
LKLMECAK_01514 1e-69 K transcriptional
LKLMECAK_01515 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
LKLMECAK_01516 8.8e-53 yodB K transcriptional
LKLMECAK_01517 1.5e-258 T His Kinase A (phosphoacceptor) domain
LKLMECAK_01518 1.4e-121 K Transcriptional regulatory protein, C terminal
LKLMECAK_01519 3.1e-136 mutG S ABC-2 family transporter protein
LKLMECAK_01520 4.9e-123 spaE S ABC-2 family transporter protein
LKLMECAK_01521 3.5e-126 mutF V ABC transporter, ATP-binding protein
LKLMECAK_01522 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LKLMECAK_01523 3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LKLMECAK_01524 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LKLMECAK_01525 8.6e-207 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LKLMECAK_01526 4.3e-76 yvbF K Belongs to the GbsR family
LKLMECAK_01527 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LKLMECAK_01528 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LKLMECAK_01529 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LKLMECAK_01530 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LKLMECAK_01531 3.5e-97 yvbF K Belongs to the GbsR family
LKLMECAK_01532 9.8e-104 yvbG U UPF0056 membrane protein
LKLMECAK_01533 6.4e-120 exoY M Membrane
LKLMECAK_01534 0.0 tcaA S response to antibiotic
LKLMECAK_01535 2.1e-79 yvbK 3.1.3.25 K acetyltransferase
LKLMECAK_01536 1.8e-210 EGP Major facilitator Superfamily
LKLMECAK_01537 3.3e-177
LKLMECAK_01538 7e-124 S GlcNAc-PI de-N-acetylase
LKLMECAK_01539 2.1e-142 C WbqC-like protein family
LKLMECAK_01540 4.6e-147 M Protein involved in cellulose biosynthesis
LKLMECAK_01541 8.5e-224 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LKLMECAK_01542 2e-169 5.1.3.2 M GDP-mannose 4,6 dehydratase
LKLMECAK_01543 2.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LKLMECAK_01544 8.9e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKLMECAK_01545 4.9e-235 ywaD 3.4.11.10, 3.4.11.6 S PA domain
LKLMECAK_01546 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LKLMECAK_01547 9.8e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
LKLMECAK_01548 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LKLMECAK_01549 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LKLMECAK_01550 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKLMECAK_01551 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LKLMECAK_01553 2.1e-252 araE EGP Major facilitator Superfamily
LKLMECAK_01554 5.5e-203 araR K transcriptional
LKLMECAK_01555 3.2e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKLMECAK_01557 1.5e-155 yvbU K Transcriptional regulator
LKLMECAK_01558 2.5e-156 yvbV EG EamA-like transporter family
LKLMECAK_01559 1.1e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
LKLMECAK_01561 5e-151 ybbH_1 K RpiR family transcriptional regulator
LKLMECAK_01562 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
LKLMECAK_01563 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
LKLMECAK_01564 2.8e-131 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LKLMECAK_01565 1.1e-270 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LKLMECAK_01566 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LKLMECAK_01567 1.3e-218 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKLMECAK_01568 1.5e-119 yvfI K COG2186 Transcriptional regulators
LKLMECAK_01569 3.8e-304 yvfH C L-lactate permease
LKLMECAK_01570 1.4e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LKLMECAK_01571 2.7e-32 yvfG S YvfG protein
LKLMECAK_01572 9.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
LKLMECAK_01573 4.1e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LKLMECAK_01574 4.2e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
LKLMECAK_01575 6.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LKLMECAK_01576 4.5e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKLMECAK_01577 7.5e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
LKLMECAK_01578 1.2e-202 epsI GM pyruvyl transferase
LKLMECAK_01579 1.9e-192 epsH GT2 S Glycosyltransferase like family 2
LKLMECAK_01580 7.7e-205 epsG S EpsG family
LKLMECAK_01581 4.7e-213 epsF GT4 M Glycosyl transferases group 1
LKLMECAK_01582 2.6e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKLMECAK_01583 9.1e-217 epsD GT4 M Glycosyl transferase 4-like
LKLMECAK_01584 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
LKLMECAK_01585 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
LKLMECAK_01586 3.5e-118 ywqC M biosynthesis protein
LKLMECAK_01587 2.1e-76 slr K transcriptional
LKLMECAK_01588 3.8e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
LKLMECAK_01590 3.7e-96 ywjB H RibD C-terminal domain
LKLMECAK_01591 2.2e-111 yyaS S Membrane
LKLMECAK_01592 2.3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKLMECAK_01593 1.6e-93 padC Q Phenolic acid decarboxylase
LKLMECAK_01594 7.7e-16 S Protein of unknown function (DUF1433)
LKLMECAK_01595 7.7e-18 S Protein of unknown function (DUF1433)
LKLMECAK_01596 9.8e-18 S Protein of unknown function (DUF1433)
LKLMECAK_01597 4.9e-268 I Pfam Lipase (class 3)
LKLMECAK_01598 2.6e-33
LKLMECAK_01600 1.2e-290 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
LKLMECAK_01601 5.2e-218 rafB P LacY proton/sugar symporter
LKLMECAK_01602 5.6e-183 scrR K transcriptional
LKLMECAK_01603 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LKLMECAK_01604 6.7e-164 yraN K Transcriptional regulator
LKLMECAK_01605 1.4e-209 yraM S PrpF protein
LKLMECAK_01606 9.2e-248 EGP Sugar (and other) transporter
LKLMECAK_01607 5.3e-11 yvdD 3.2.2.10 S Belongs to the LOG family
LKLMECAK_01608 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
LKLMECAK_01609 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
LKLMECAK_01610 7.3e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
LKLMECAK_01611 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LKLMECAK_01612 2.3e-181 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKLMECAK_01613 8.2e-79 M Ribonuclease
LKLMECAK_01614 5.7e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
LKLMECAK_01615 4.7e-36 crh G Phosphocarrier protein Chr
LKLMECAK_01616 5.3e-170 whiA K May be required for sporulation
LKLMECAK_01617 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LKLMECAK_01618 1.1e-166 rapZ S Displays ATPase and GTPase activities
LKLMECAK_01619 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LKLMECAK_01620 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LKLMECAK_01621 1.3e-124 usp CBM50 M protein conserved in bacteria
LKLMECAK_01622 2.5e-275 S COG0457 FOG TPR repeat
LKLMECAK_01623 2.3e-190 sasA T Histidine kinase
LKLMECAK_01624 9.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKLMECAK_01625 6.8e-54
LKLMECAK_01626 0.0 msbA2 3.6.3.44 V ABC transporter
LKLMECAK_01627 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
LKLMECAK_01628 4.9e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LKLMECAK_01629 1.3e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LKLMECAK_01630 1.6e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LKLMECAK_01631 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LKLMECAK_01632 1.4e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LKLMECAK_01633 5.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LKLMECAK_01634 1e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LKLMECAK_01635 3.5e-137 yvpB NU protein conserved in bacteria
LKLMECAK_01636 2.4e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
LKLMECAK_01637 5.3e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LKLMECAK_01638 6.4e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LKLMECAK_01639 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LKLMECAK_01640 1.5e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LKLMECAK_01641 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LKLMECAK_01642 2.3e-133 yvoA K transcriptional
LKLMECAK_01643 4.4e-103 yxaF K Transcriptional regulator
LKLMECAK_01644 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
LKLMECAK_01645 1.5e-40 yvlD S Membrane
LKLMECAK_01646 9.6e-26 pspB KT PspC domain
LKLMECAK_01647 1.2e-165 yvlB S Putative adhesin
LKLMECAK_01648 6.1e-49 yvlA
LKLMECAK_01649 2.2e-32 yvkN
LKLMECAK_01650 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LKLMECAK_01651 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LKLMECAK_01652 7.6e-33 csbA S protein conserved in bacteria
LKLMECAK_01653 0.0 yvkC 2.7.9.2 GT Phosphotransferase
LKLMECAK_01654 2e-109 yvkB K Transcriptional regulator
LKLMECAK_01655 9.6e-226 yvkA EGP Major facilitator Superfamily
LKLMECAK_01656 1.1e-174 S Psort location CytoplasmicMembrane, score
LKLMECAK_01657 8.3e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKLMECAK_01658 1.5e-55 swrA S Swarming motility protein
LKLMECAK_01659 2.4e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
LKLMECAK_01660 4.3e-224 ywoF P Right handed beta helix region
LKLMECAK_01661 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LKLMECAK_01662 2.3e-122 ftsE D cell division ATP-binding protein FtsE
LKLMECAK_01663 6.2e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
LKLMECAK_01664 1.3e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
LKLMECAK_01665 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LKLMECAK_01666 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LKLMECAK_01667 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LKLMECAK_01668 6.8e-68
LKLMECAK_01669 3.5e-10 fliT S bacterial-type flagellum organization
LKLMECAK_01670 3e-66 fliS N flagellar protein FliS
LKLMECAK_01671 2e-243 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LKLMECAK_01672 3.2e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LKLMECAK_01673 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LKLMECAK_01674 7.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LKLMECAK_01675 8.9e-80 yviE
LKLMECAK_01676 2.3e-162 flgL N Belongs to the bacterial flagellin family
LKLMECAK_01677 1.4e-273 flgK N flagellar hook-associated protein
LKLMECAK_01678 8.9e-81 flgN NOU FlgN protein
LKLMECAK_01679 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
LKLMECAK_01680 1.2e-73 yvyF S flagellar protein
LKLMECAK_01681 6.6e-108 comFC S Phosphoribosyl transferase domain
LKLMECAK_01682 1.1e-41 comFB S Late competence development protein ComFB
LKLMECAK_01683 1.3e-254 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LKLMECAK_01684 1.9e-158 degV S protein conserved in bacteria
LKLMECAK_01685 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKLMECAK_01686 6.3e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LKLMECAK_01687 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
LKLMECAK_01688 3.9e-165 yvhJ K Transcriptional regulator
LKLMECAK_01689 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LKLMECAK_01690 1.1e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
LKLMECAK_01691 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
LKLMECAK_01692 3.3e-113 tuaF M protein involved in exopolysaccharide biosynthesis
LKLMECAK_01693 1.5e-253 tuaE M Teichuronic acid biosynthesis protein
LKLMECAK_01694 4.9e-246 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKLMECAK_01695 2.6e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
LKLMECAK_01696 1.8e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKLMECAK_01697 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LKLMECAK_01698 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKLMECAK_01699 0.0 lytB 3.5.1.28 D Stage II sporulation protein
LKLMECAK_01700 2.3e-48
LKLMECAK_01701 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LKLMECAK_01702 2e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LKLMECAK_01703 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LKLMECAK_01704 1.1e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LKLMECAK_01705 1.7e-151 tagG GM Transport permease protein
LKLMECAK_01706 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LKLMECAK_01707 7.8e-280 M Glycosyltransferase like family 2
LKLMECAK_01708 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
LKLMECAK_01709 3.8e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LKLMECAK_01710 5.5e-217 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LKLMECAK_01711 2.3e-239 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKLMECAK_01712 7.7e-185 pmi 5.3.1.8 G mannose-6-phosphate isomerase
LKLMECAK_01713 9.7e-264 gerBA EG Spore germination protein
LKLMECAK_01714 7.8e-197 gerBB E Spore germination protein
LKLMECAK_01715 2.4e-209 gerAC S Spore germination protein
LKLMECAK_01716 1.5e-266 GT2,GT4 J Glycosyl transferase family 2
LKLMECAK_01717 4.9e-249 ywtG EGP Major facilitator Superfamily
LKLMECAK_01718 7.2e-178 ywtF K Transcriptional regulator
LKLMECAK_01719 4.7e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
LKLMECAK_01720 3.2e-34 yttA 2.7.13.3 S Pfam Transposase IS66
LKLMECAK_01721 7.3e-236 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LKLMECAK_01722 1.3e-20 ywtC
LKLMECAK_01723 2.8e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LKLMECAK_01724 2.3e-70 pgsC S biosynthesis protein
LKLMECAK_01725 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
LKLMECAK_01726 7.7e-184 gerKA EG Spore germination protein
LKLMECAK_01727 8.2e-191 gerKB E Spore germination protein
LKLMECAK_01728 1.5e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
LKLMECAK_01729 3.2e-178 rbsR K transcriptional
LKLMECAK_01730 2.4e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LKLMECAK_01731 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LKLMECAK_01732 7.1e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LKLMECAK_01733 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
LKLMECAK_01734 3.7e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
LKLMECAK_01735 9.8e-89 batE T Sh3 type 3 domain protein
LKLMECAK_01736 5.3e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
LKLMECAK_01737 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
LKLMECAK_01738 2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LKLMECAK_01739 2.6e-166 alsR K LysR substrate binding domain
LKLMECAK_01741 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKLMECAK_01742 7.5e-126 ywrJ
LKLMECAK_01743 2.8e-128 cotB
LKLMECAK_01744 5e-212 cotH M Spore Coat
LKLMECAK_01745 2e-09
LKLMECAK_01746 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LKLMECAK_01748 1.4e-300 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LKLMECAK_01749 2.5e-83 ywrC K Transcriptional regulator
LKLMECAK_01750 9.5e-101 ywrB P Chromate transporter
LKLMECAK_01751 1.6e-86 ywrA P COG2059 Chromate transport protein ChrA
LKLMECAK_01753 1.5e-92 ywqN S NAD(P)H-dependent
LKLMECAK_01754 9e-156 K Transcriptional regulator
LKLMECAK_01755 8.4e-131 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LKLMECAK_01756 9.7e-14
LKLMECAK_01758 7.5e-306 ywqJ S Pre-toxin TG
LKLMECAK_01759 7.3e-37 ywqI S Family of unknown function (DUF5344)
LKLMECAK_01760 1.4e-21 S Domain of unknown function (DUF5082)
LKLMECAK_01762 3.4e-146 ywqG S Domain of unknown function (DUF1963)
LKLMECAK_01763 2.9e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKLMECAK_01764 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
LKLMECAK_01765 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
LKLMECAK_01766 1.8e-109 ywqC M biosynthesis protein
LKLMECAK_01767 1.3e-14
LKLMECAK_01768 1.6e-307 ywqB S SWIM zinc finger
LKLMECAK_01769 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LKLMECAK_01770 1.7e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
LKLMECAK_01771 7.5e-138 glcR K DeoR C terminal sensor domain
LKLMECAK_01772 3.7e-57 ssbB L Single-stranded DNA-binding protein
LKLMECAK_01773 4e-62 ywpG
LKLMECAK_01774 2.5e-68 ywpF S YwpF-like protein
LKLMECAK_01775 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LKLMECAK_01776 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LKLMECAK_01777 5.2e-198 S aspartate phosphatase
LKLMECAK_01778 4.5e-141 flhP N flagellar basal body
LKLMECAK_01779 5.5e-128 flhO N flagellar basal body
LKLMECAK_01780 2.7e-180 mbl D Rod shape-determining protein
LKLMECAK_01781 1.8e-44 spoIIID K Stage III sporulation protein D
LKLMECAK_01782 2.5e-71 ywoH K transcriptional
LKLMECAK_01783 1.4e-212 ywoG EGP Major facilitator Superfamily
LKLMECAK_01784 4.6e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
LKLMECAK_01785 1.6e-244 ywoD EGP Major facilitator superfamily
LKLMECAK_01786 4.8e-102 phzA Q Isochorismatase family
LKLMECAK_01787 9.3e-228 amt P Ammonium transporter
LKLMECAK_01788 2e-58 nrgB K Belongs to the P(II) protein family
LKLMECAK_01789 5.1e-207 ftsW D Belongs to the SEDS family
LKLMECAK_01790 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
LKLMECAK_01791 8.1e-70 ywnJ S VanZ like family
LKLMECAK_01792 1.4e-121 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
LKLMECAK_01793 9.2e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
LKLMECAK_01794 1.2e-10 ywnC S Family of unknown function (DUF5362)
LKLMECAK_01795 4.2e-69 ywnF S Family of unknown function (DUF5392)
LKLMECAK_01796 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKLMECAK_01797 1.2e-51 ywnC S Family of unknown function (DUF5362)
LKLMECAK_01798 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
LKLMECAK_01800 6.1e-67 ywnA K Transcriptional regulator
LKLMECAK_01801 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LKLMECAK_01802 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LKLMECAK_01803 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LKLMECAK_01804 3.2e-10 csbD K CsbD-like
LKLMECAK_01805 2.3e-81 ywmF S Peptidase M50
LKLMECAK_01806 3.7e-93 S response regulator aspartate phosphatase
LKLMECAK_01807 1.2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LKLMECAK_01808 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LKLMECAK_01810 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
LKLMECAK_01811 5.1e-114 ywmC S protein containing a von Willebrand factor type A (vWA) domain
LKLMECAK_01812 4e-179 spoIID D Stage II sporulation protein D
LKLMECAK_01813 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LKLMECAK_01814 2.2e-134 ywmB S TATA-box binding
LKLMECAK_01815 4.8e-32 ywzB S membrane
LKLMECAK_01816 8.7e-89 ywmA
LKLMECAK_01817 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LKLMECAK_01818 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LKLMECAK_01819 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LKLMECAK_01820 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LKLMECAK_01821 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKLMECAK_01822 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LKLMECAK_01823 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKLMECAK_01824 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
LKLMECAK_01825 2.1e-61 atpI S ATP synthase
LKLMECAK_01826 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LKLMECAK_01827 5.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LKLMECAK_01828 1e-96 ywlG S Belongs to the UPF0340 family
LKLMECAK_01829 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
LKLMECAK_01830 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LKLMECAK_01831 1.3e-83 mntP P Probably functions as a manganese efflux pump
LKLMECAK_01832 1.5e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LKLMECAK_01833 1.1e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
LKLMECAK_01834 8.9e-119 spoIIR S stage II sporulation protein R
LKLMECAK_01835 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
LKLMECAK_01837 4.8e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LKLMECAK_01838 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LKLMECAK_01839 2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKLMECAK_01840 2.2e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LKLMECAK_01841 6.8e-157 ywkB S Membrane transport protein
LKLMECAK_01842 0.0 sfcA 1.1.1.38 C malic enzyme
LKLMECAK_01843 2.5e-101 tdk 2.7.1.21 F thymidine kinase
LKLMECAK_01844 1.1e-32 rpmE J Binds the 23S rRNA
LKLMECAK_01845 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LKLMECAK_01846 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
LKLMECAK_01847 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LKLMECAK_01848 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LKLMECAK_01849 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
LKLMECAK_01850 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
LKLMECAK_01851 4.2e-92 ywjG S Domain of unknown function (DUF2529)
LKLMECAK_01852 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LKLMECAK_01853 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LKLMECAK_01854 0.0 fadF C COG0247 Fe-S oxidoreductase
LKLMECAK_01855 2.3e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LKLMECAK_01856 2.2e-179 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LKLMECAK_01857 4.2e-43 ywjC
LKLMECAK_01858 0.0 ywjA V ABC transporter
LKLMECAK_01859 1.6e-296 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKLMECAK_01860 3.4e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKLMECAK_01861 2.1e-120 narI 1.7.5.1 C nitrate reductase, gamma
LKLMECAK_01862 1.7e-91 narJ 1.7.5.1 C nitrate reductase
LKLMECAK_01863 3.7e-295 narH 1.7.5.1 C Nitrate reductase, beta
LKLMECAK_01864 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKLMECAK_01865 1.7e-84 arfM T cyclic nucleotide binding
LKLMECAK_01866 2.8e-139 ywiC S YwiC-like protein
LKLMECAK_01867 8.5e-128 fnr K helix_turn_helix, cAMP Regulatory protein
LKLMECAK_01868 5.4e-212 narK P COG2223 Nitrate nitrite transporter
LKLMECAK_01869 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LKLMECAK_01870 2.9e-43 ywiB S protein conserved in bacteria
LKLMECAK_01871 4.7e-72 S aspartate phosphatase
LKLMECAK_01873 9.7e-29 ydcG K sequence-specific DNA binding
LKLMECAK_01874 1.6e-31
LKLMECAK_01876 1.3e-74 CP Membrane
LKLMECAK_01879 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
LKLMECAK_01880 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LKLMECAK_01881 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LKLMECAK_01882 1.8e-80
LKLMECAK_01883 1.9e-92 ywhD S YwhD family
LKLMECAK_01884 1.2e-117 ywhC S Peptidase family M50
LKLMECAK_01885 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
LKLMECAK_01886 4.9e-67 ywhA K Transcriptional regulator
LKLMECAK_01887 1.9e-245 yhdG_1 E C-terminus of AA_permease
LKLMECAK_01888 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
LKLMECAK_01889 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
LKLMECAK_01890 6.9e-36 ywzC S Belongs to the UPF0741 family
LKLMECAK_01891 6.6e-110 rsfA_1
LKLMECAK_01892 9.7e-52 padR K PadR family transcriptional regulator
LKLMECAK_01893 3.4e-92 S membrane
LKLMECAK_01894 2.1e-163 V ABC transporter, ATP-binding protein
LKLMECAK_01895 7.2e-167 yhcI S ABC transporter (permease)
LKLMECAK_01898 4.5e-174
LKLMECAK_01900 1.2e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LKLMECAK_01901 6e-163 cysL K Transcriptional regulator
LKLMECAK_01902 6.2e-158 MA20_14895 S Conserved hypothetical protein 698
LKLMECAK_01903 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
LKLMECAK_01904 1.1e-146 ywfI C May function as heme-dependent peroxidase
LKLMECAK_01905 1.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
LKLMECAK_01906 8.6e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
LKLMECAK_01907 1e-207 bacE EGP Major facilitator Superfamily
LKLMECAK_01908 2.4e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LKLMECAK_01909 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKLMECAK_01910 7.6e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LKLMECAK_01911 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LKLMECAK_01912 3.5e-222 ywfA EGP Major facilitator Superfamily
LKLMECAK_01913 2.5e-204 tcaB EGP Major facilitator Superfamily
LKLMECAK_01914 1.2e-258 lysP E amino acid
LKLMECAK_01915 0.0 rocB E arginine degradation protein
LKLMECAK_01916 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LKLMECAK_01917 7.3e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LKLMECAK_01918 1.9e-59
LKLMECAK_01919 3e-86 spsL 5.1.3.13 M Spore Coat
LKLMECAK_01920 4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LKLMECAK_01921 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LKLMECAK_01922 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LKLMECAK_01923 1.7e-179 spsG M Spore Coat
LKLMECAK_01924 2.6e-132 spsF M Spore Coat
LKLMECAK_01925 1.2e-213 spsE 2.5.1.56 M acid synthase
LKLMECAK_01926 8.9e-156 spsD 2.3.1.210 K Spore Coat
LKLMECAK_01927 4e-220 spsC E Belongs to the DegT DnrJ EryC1 family
LKLMECAK_01928 9.1e-275 spsB M Capsule polysaccharide biosynthesis protein
LKLMECAK_01929 1.7e-142 spsA M Spore Coat
LKLMECAK_01930 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LKLMECAK_01931 4.2e-46 ywdK S small membrane protein
LKLMECAK_01932 5.4e-229 ywdJ F Xanthine uracil
LKLMECAK_01933 4.7e-41 ywdI S Family of unknown function (DUF5327)
LKLMECAK_01934 1.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LKLMECAK_01935 6.8e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
LKLMECAK_01937 1.5e-88 ywdD
LKLMECAK_01938 6.3e-57 pex K Transcriptional regulator PadR-like family
LKLMECAK_01939 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LKLMECAK_01940 7.4e-20 ywdA
LKLMECAK_01941 1.9e-283 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
LKLMECAK_01942 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKLMECAK_01943 2.8e-151 sacT K transcriptional antiterminator
LKLMECAK_01945 0.0 vpr O Belongs to the peptidase S8 family
LKLMECAK_01946 6.8e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKLMECAK_01947 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
LKLMECAK_01948 2.8e-208 rodA D Belongs to the SEDS family
LKLMECAK_01949 1.7e-76 ysnE K acetyltransferase
LKLMECAK_01950 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
LKLMECAK_01951 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LKLMECAK_01952 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LKLMECAK_01953 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LKLMECAK_01954 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LKLMECAK_01955 8.4e-27 ywzA S membrane
LKLMECAK_01956 3.6e-293 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LKLMECAK_01957 5.1e-61 gtcA S GtrA-like protein
LKLMECAK_01958 3.1e-110 ywcC K Bacterial regulatory proteins, tetR family
LKLMECAK_01960 1.1e-127 H Methionine biosynthesis protein MetW
LKLMECAK_01961 1.2e-131 S Streptomycin biosynthesis protein StrF
LKLMECAK_01962 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LKLMECAK_01963 1.1e-242 ywbN P Dyp-type peroxidase family protein
LKLMECAK_01964 7.2e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LKLMECAK_01965 1.3e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LKLMECAK_01966 8.2e-152 ywbI K Transcriptional regulator
LKLMECAK_01967 4.2e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LKLMECAK_01968 1.3e-109 ywbG M effector of murein hydrolase
LKLMECAK_01969 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
LKLMECAK_01970 2.6e-135 mta K transcriptional
LKLMECAK_01971 3e-223 ywbD 2.1.1.191 J Methyltransferase
LKLMECAK_01972 7.6e-67 ywbC 4.4.1.5 E glyoxalase
LKLMECAK_01973 7.1e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKLMECAK_01974 6.4e-262 epr 3.4.21.62 O Belongs to the peptidase S8 family
LKLMECAK_01975 4.1e-161 gspA M General stress
LKLMECAK_01976 7.1e-49 ywaE K Transcriptional regulator
LKLMECAK_01977 1.9e-196 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKLMECAK_01978 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
LKLMECAK_01979 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
LKLMECAK_01980 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
LKLMECAK_01981 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_01982 1.1e-228 dltB M membrane protein involved in D-alanine export
LKLMECAK_01983 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_01984 3.1e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LKLMECAK_01985 7.1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LKLMECAK_01986 3e-251 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LKLMECAK_01987 5.1e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
LKLMECAK_01988 7.4e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKLMECAK_01989 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
LKLMECAK_01990 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
LKLMECAK_01991 1.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LKLMECAK_01992 4.7e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKLMECAK_01993 7.9e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKLMECAK_01994 1.5e-166 cbrA3 P Periplasmic binding protein
LKLMECAK_01995 1.7e-57 arsR K transcriptional
LKLMECAK_01996 2.5e-226 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKLMECAK_01997 1.3e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
LKLMECAK_01998 2.3e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
LKLMECAK_01999 2.3e-227 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKLMECAK_02000 2.1e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LKLMECAK_02001 2.4e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
LKLMECAK_02002 6.9e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
LKLMECAK_02003 2.1e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
LKLMECAK_02004 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LKLMECAK_02005 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LKLMECAK_02006 1e-251 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
LKLMECAK_02007 8e-154 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LKLMECAK_02008 1.3e-291 cydD V ATP-binding protein
LKLMECAK_02009 0.0 cydD V ATP-binding
LKLMECAK_02010 1.1e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
LKLMECAK_02011 4.5e-266 cydA 1.10.3.14 C oxidase, subunit
LKLMECAK_02012 1e-214 cimH C COG3493 Na citrate symporter
LKLMECAK_02013 1.6e-154 yxkH G Polysaccharide deacetylase
LKLMECAK_02014 2.6e-205 msmK P Belongs to the ABC transporter superfamily
LKLMECAK_02015 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
LKLMECAK_02016 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKLMECAK_02017 3.8e-87 yxkC S Domain of unknown function (DUF4352)
LKLMECAK_02018 8.2e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LKLMECAK_02019 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LKLMECAK_02022 2e-85 yxjI S LURP-one-related
LKLMECAK_02023 4.8e-218 yxjG 2.1.1.14 E Methionine synthase
LKLMECAK_02024 5.9e-155 rlmA 2.1.1.187 Q Methyltransferase domain
LKLMECAK_02025 3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKLMECAK_02026 3.6e-72 T Domain of unknown function (DUF4163)
LKLMECAK_02027 1.5e-49 yxiS
LKLMECAK_02028 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
LKLMECAK_02029 1.4e-221 citH C Citrate transporter
LKLMECAK_02030 2e-140 exoK GH16 M licheninase activity
LKLMECAK_02032 2.3e-70 licT K transcriptional antiterminator
LKLMECAK_02033 2.7e-20 licT K transcriptional antiterminator
LKLMECAK_02034 4.3e-220 yxiO S COG2270 Permeases of the major facilitator superfamily
LKLMECAK_02035 2e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LKLMECAK_02037 2.8e-20
LKLMECAK_02038 3.7e-13 S YxiJ-like protein
LKLMECAK_02039 3.2e-110
LKLMECAK_02043 9.3e-88
LKLMECAK_02044 0.0 wapA M COG3209 Rhs family protein
LKLMECAK_02045 5.5e-200 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
LKLMECAK_02046 3.6e-147 yxxF EG EamA-like transporter family
LKLMECAK_02047 1.8e-72 yxiE T Belongs to the universal stress protein A family
LKLMECAK_02048 0.0 L HKD family nuclease
LKLMECAK_02049 9.5e-65 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LKLMECAK_02050 2.6e-274 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LKLMECAK_02051 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LKLMECAK_02052 1.1e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
LKLMECAK_02053 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LKLMECAK_02054 6.3e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
LKLMECAK_02055 9.4e-175 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LKLMECAK_02056 4.4e-253 lysP E amino acid
LKLMECAK_02057 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
LKLMECAK_02058 6.8e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKLMECAK_02059 3.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LKLMECAK_02060 9.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LKLMECAK_02061 2.6e-149 yidA S hydrolases of the HAD superfamily
LKLMECAK_02065 3.4e-17 yxeD
LKLMECAK_02066 1.3e-34
LKLMECAK_02067 4.1e-178 fhuD P Periplasmic binding protein
LKLMECAK_02068 1.3e-57 yxeA S Protein of unknown function (DUF1093)
LKLMECAK_02069 0.0 yxdM V ABC transporter (permease)
LKLMECAK_02070 3.6e-140 yxdL V ABC transporter, ATP-binding protein
LKLMECAK_02071 2.5e-175 T PhoQ Sensor
LKLMECAK_02072 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKLMECAK_02073 1.8e-156 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LKLMECAK_02074 2.5e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LKLMECAK_02075 3.3e-166 iolH G Xylose isomerase-like TIM barrel
LKLMECAK_02076 2e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LKLMECAK_02077 6.7e-232 iolF EGP Major facilitator Superfamily
LKLMECAK_02078 3.4e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LKLMECAK_02079 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LKLMECAK_02080 2.7e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LKLMECAK_02081 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LKLMECAK_02082 4.8e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKLMECAK_02083 2e-135 iolR K COG1349 Transcriptional regulators of sugar metabolism
LKLMECAK_02084 4.6e-174 iolS C Aldo keto reductase
LKLMECAK_02085 4.3e-245 csbC EGP Major facilitator Superfamily
LKLMECAK_02086 0.0 htpG O Molecular chaperone. Has ATPase activity
LKLMECAK_02088 4.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
LKLMECAK_02089 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKLMECAK_02090 4.5e-200 desK 2.7.13.3 T Histidine kinase
LKLMECAK_02091 1.8e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
LKLMECAK_02092 6.2e-213 yxbF K Bacterial regulatory proteins, tetR family
LKLMECAK_02093 5.2e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LKLMECAK_02094 2.8e-142 S PQQ-like domain
LKLMECAK_02095 1.7e-64 S Family of unknown function (DUF5391)
LKLMECAK_02096 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
LKLMECAK_02097 2.9e-202 EGP Major facilitator Superfamily
LKLMECAK_02098 3.8e-73 yxaI S membrane protein domain
LKLMECAK_02099 1.7e-125 E Ring-cleavage extradiol dioxygenase
LKLMECAK_02100 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
LKLMECAK_02101 2.3e-287 ahpF O Alkyl hydroperoxide reductase
LKLMECAK_02102 9.3e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
LKLMECAK_02103 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
LKLMECAK_02104 1.2e-82 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LKLMECAK_02105 1.2e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LKLMECAK_02106 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LKLMECAK_02107 4.6e-90 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
LKLMECAK_02108 1.4e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LKLMECAK_02109 1.8e-176 S Fusaric acid resistance protein-like
LKLMECAK_02110 2.7e-17
LKLMECAK_02111 3.6e-20
LKLMECAK_02112 4.1e-223
LKLMECAK_02113 2.4e-108 mjecl24 D Involved in chromosome partitioning
LKLMECAK_02114 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LKLMECAK_02115 7.9e-08 S YyzF-like protein
LKLMECAK_02117 4.6e-216 yycP
LKLMECAK_02118 4.5e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LKLMECAK_02119 1.5e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
LKLMECAK_02120 1.4e-86 yycN 2.3.1.128 K Acetyltransferase
LKLMECAK_02122 1.1e-198 S Histidine kinase
LKLMECAK_02123 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
LKLMECAK_02124 1.1e-256 rocE E amino acid
LKLMECAK_02125 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
LKLMECAK_02126 7.7e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LKLMECAK_02127 5.9e-145 1.14.11.27 P peptidyl-arginine hydroxylation
LKLMECAK_02128 1.3e-304 S ABC transporter
LKLMECAK_02129 4.5e-195 S Major Facilitator Superfamily
LKLMECAK_02130 6.1e-257
LKLMECAK_02131 2.7e-188 2.7.7.73, 2.7.7.80 H ThiF family
LKLMECAK_02132 1.5e-248 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
LKLMECAK_02133 2.8e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKLMECAK_02134 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKLMECAK_02135 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LKLMECAK_02136 1.1e-150 yycI S protein conserved in bacteria
LKLMECAK_02137 2.5e-261 yycH S protein conserved in bacteria
LKLMECAK_02138 0.0 vicK 2.7.13.3 T Histidine kinase
LKLMECAK_02139 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKLMECAK_02144 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LKLMECAK_02145 8.5e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKLMECAK_02146 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LKLMECAK_02147 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
LKLMECAK_02149 4.6e-17 yycC K YycC-like protein
LKLMECAK_02150 6.4e-235 M Glycosyltransferase Family 4
LKLMECAK_02151 2.6e-202 S Ecdysteroid kinase
LKLMECAK_02152 2.5e-233 S Carbamoyl-phosphate synthase L chain, ATP binding domain
LKLMECAK_02153 3.6e-241 M Glycosyltransferase Family 4
LKLMECAK_02154 4.9e-122 S GlcNAc-PI de-N-acetylase
LKLMECAK_02155 6.4e-122 KLT COG0515 Serine threonine protein kinase
LKLMECAK_02156 4.9e-73 rplI J binds to the 23S rRNA
LKLMECAK_02157 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LKLMECAK_02158 2.4e-159 yybS S membrane
LKLMECAK_02160 2.5e-83 cotF M Spore coat protein
LKLMECAK_02161 8.2e-66 ydeP3 K Transcriptional regulator
LKLMECAK_02162 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
LKLMECAK_02163 5.3e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LKLMECAK_02164 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
LKLMECAK_02165 2.1e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
LKLMECAK_02166 2.2e-114 K FCD domain
LKLMECAK_02167 6.3e-77 dinB S PFAM DinB family protein
LKLMECAK_02168 3.2e-159 G Major Facilitator Superfamily
LKLMECAK_02169 2.2e-55 ypaA S Protein of unknown function (DUF1304)
LKLMECAK_02170 5.6e-115 drgA C nitroreductase
LKLMECAK_02171 4.1e-69 ydgJ K Winged helix DNA-binding domain
LKLMECAK_02172 1.5e-150 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LKLMECAK_02173 1.6e-76 yybA 2.3.1.57 K transcriptional
LKLMECAK_02174 6.4e-162 eaeH M Domain of Unknown Function (DUF1259)
LKLMECAK_02175 5.2e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
LKLMECAK_02176 4.3e-161 K Transcriptional regulator
LKLMECAK_02177 1.9e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LKLMECAK_02178 3.6e-94
LKLMECAK_02179 4.5e-66 S Leucine-rich repeat (LRR) protein
LKLMECAK_02180 4.2e-19
LKLMECAK_02181 8.5e-70 isp O Belongs to the peptidase S8 family
LKLMECAK_02182 7.2e-251 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKLMECAK_02183 2.6e-129 ydfC EG EamA-like transporter family
LKLMECAK_02184 1.5e-96 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LKLMECAK_02185 3.3e-78 K Transcriptional regulator
LKLMECAK_02186 7.6e-14 yvaO K Transcriptional
LKLMECAK_02187 2.7e-40 qacC U Small Multidrug Resistance protein
LKLMECAK_02188 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
LKLMECAK_02189 1.9e-161 yyaK S CAAX protease self-immunity
LKLMECAK_02190 2.6e-247 ydjK G Sugar (and other) transporter
LKLMECAK_02191 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKLMECAK_02192 2.6e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
LKLMECAK_02193 2.7e-140 xth 3.1.11.2 L exodeoxyribonuclease III
LKLMECAK_02194 4.6e-97 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKLMECAK_02195 2.4e-104 adaA 3.2.2.21 K Transcriptional regulator
LKLMECAK_02196 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LKLMECAK_02197 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LKLMECAK_02198 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
LKLMECAK_02199 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LKLMECAK_02200 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKLMECAK_02201 2.3e-33 yyzM S protein conserved in bacteria
LKLMECAK_02202 2.4e-176 yyaD S Membrane
LKLMECAK_02203 1.2e-46 4.2.1.103 K FR47-like protein
LKLMECAK_02204 6.2e-111 yyaC S Sporulation protein YyaC
LKLMECAK_02205 7.9e-149 spo0J K Belongs to the ParB family
LKLMECAK_02206 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
LKLMECAK_02207 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LKLMECAK_02208 1.6e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LKLMECAK_02209 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LKLMECAK_02210 2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LKLMECAK_02211 1.3e-108 jag S single-stranded nucleic acid binding R3H
LKLMECAK_02212 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKLMECAK_02213 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LKLMECAK_02214 2.3e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LKLMECAK_02215 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LKLMECAK_02216 2.4e-33 yaaA S S4 domain
LKLMECAK_02217 1.6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LKLMECAK_02218 8.1e-38 yaaB S Domain of unknown function (DUF370)
LKLMECAK_02219 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKLMECAK_02220 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKLMECAK_02221 7e-181 yaaC S YaaC-like Protein
LKLMECAK_02222 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LKLMECAK_02223 2.3e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LKLMECAK_02224 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LKLMECAK_02225 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LKLMECAK_02226 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LKLMECAK_02227 1.3e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LKLMECAK_02228 1.3e-09
LKLMECAK_02229 4.5e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
LKLMECAK_02230 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
LKLMECAK_02231 3.8e-211 yaaH M Glycoside Hydrolase Family
LKLMECAK_02232 1.8e-98 yaaI Q COG1335 Amidases related to nicotinamidase
LKLMECAK_02233 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LKLMECAK_02234 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKLMECAK_02235 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LKLMECAK_02236 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LKLMECAK_02237 3.6e-32 yaaL S Protein of unknown function (DUF2508)
LKLMECAK_02238 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
LKLMECAK_02239 1.1e-164 ygxA S Nucleotidyltransferase-like
LKLMECAK_02240 1.5e-56 ygzB S UPF0295 protein
LKLMECAK_02241 1.8e-80 perR P Belongs to the Fur family
LKLMECAK_02242 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
LKLMECAK_02243 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LKLMECAK_02244 2.7e-178 ygaE S Membrane
LKLMECAK_02245 9.1e-301 ygaD V ABC transporter
LKLMECAK_02246 2.2e-104 ygaC J Belongs to the UPF0374 family
LKLMECAK_02247 1.5e-37 ygaB S YgaB-like protein
LKLMECAK_02249 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKLMECAK_02250 3.1e-36 yfhS
LKLMECAK_02251 4.8e-207 mutY L A G-specific
LKLMECAK_02252 1e-184 yfhP S membrane-bound metal-dependent
LKLMECAK_02253 0.0 yfhO S Bacterial membrane protein YfhO
LKLMECAK_02254 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKLMECAK_02255 9.1e-169 yfhM S Alpha/beta hydrolase family
LKLMECAK_02256 9.7e-34 yfhL S SdpI/YhfL protein family
LKLMECAK_02257 8.5e-93 batE T Bacterial SH3 domain homologues
LKLMECAK_02258 2.2e-44 yfhJ S WVELL protein
LKLMECAK_02259 2e-166 mpr 3.4.21.19 M Belongs to the peptidase S1B family
LKLMECAK_02261 1.1e-204 yfhI EGP Major facilitator Superfamily
LKLMECAK_02262 2.5e-52 yfhH S Protein of unknown function (DUF1811)
LKLMECAK_02263 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
LKLMECAK_02264 3.4e-166 yfhF S nucleoside-diphosphate sugar epimerase
LKLMECAK_02266 2.1e-25 yfhD S YfhD-like protein
LKLMECAK_02267 1.7e-105 yfhC C nitroreductase
LKLMECAK_02268 7.2e-161 yfhB 5.3.3.17 S PhzF family
LKLMECAK_02269 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LKLMECAK_02270 6.2e-82 yfiV K transcriptional
LKLMECAK_02271 4.7e-288 yfiU EGP Major facilitator Superfamily
LKLMECAK_02272 2.4e-43 yfiT S Belongs to the metal hydrolase YfiT family
LKLMECAK_02273 4.5e-45 yrdF K ribonuclease inhibitor
LKLMECAK_02274 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
LKLMECAK_02275 1.9e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LKLMECAK_02276 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
LKLMECAK_02277 6.6e-96 padR K transcriptional
LKLMECAK_02278 1.7e-163 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LKLMECAK_02279 1.7e-159 yfiE 1.13.11.2 S glyoxalase
LKLMECAK_02280 9.2e-63 mhqP S DoxX
LKLMECAK_02281 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
LKLMECAK_02282 2.4e-309 yfiB3 V ABC transporter
LKLMECAK_02283 3.2e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKLMECAK_02284 5.1e-139 glvR F Helix-turn-helix domain, rpiR family
LKLMECAK_02285 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LKLMECAK_02286 4.2e-15 sspH S Belongs to the SspH family
LKLMECAK_02287 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
LKLMECAK_02288 2.3e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKLMECAK_02289 1.4e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKLMECAK_02290 4.7e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKLMECAK_02291 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKLMECAK_02292 2.8e-87 yfjM S Psort location Cytoplasmic, score
LKLMECAK_02293 3.5e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LKLMECAK_02294 8.7e-44 S YfzA-like protein
LKLMECAK_02295 1.8e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKLMECAK_02296 8.3e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LKLMECAK_02297 8.5e-184 corA P Mediates influx of magnesium ions
LKLMECAK_02298 3.3e-30
LKLMECAK_02299 7.5e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LKLMECAK_02300 9e-155 pdaA G deacetylase
LKLMECAK_02301 4.9e-27 yfjT
LKLMECAK_02302 7.3e-219 yfkA S YfkB-like domain
LKLMECAK_02303 1e-145 yfkC M Mechanosensitive ion channel
LKLMECAK_02304 1.6e-143 yfkD S YfkD-like protein
LKLMECAK_02305 8.5e-185 cax P COG0387 Ca2 H antiporter
LKLMECAK_02306 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
LKLMECAK_02307 2.5e-07
LKLMECAK_02308 7.6e-144 yihY S Belongs to the UPF0761 family
LKLMECAK_02309 1e-51 yfkI S gas vesicle protein
LKLMECAK_02310 1.2e-27 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LKLMECAK_02311 4.6e-35 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LKLMECAK_02312 2.3e-29 yfkK S Belongs to the UPF0435 family
LKLMECAK_02313 8.1e-192 ydiM EGP Major facilitator Superfamily
LKLMECAK_02314 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LKLMECAK_02315 5.6e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LKLMECAK_02316 9.8e-186 K helix_turn _helix lactose operon repressor
LKLMECAK_02317 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
LKLMECAK_02318 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
LKLMECAK_02319 9.4e-198 yibE S YibE/F-like protein
LKLMECAK_02320 1e-123 yibF S YibE/F-like protein
LKLMECAK_02321 1.7e-122 yfkO C nitroreductase
LKLMECAK_02322 2e-129 treR K transcriptional
LKLMECAK_02323 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LKLMECAK_02324 2.1e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKLMECAK_02325 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
LKLMECAK_02326 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
LKLMECAK_02327 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
LKLMECAK_02328 2.3e-63 yhdN S Domain of unknown function (DUF1992)
LKLMECAK_02329 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LKLMECAK_02330 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
LKLMECAK_02331 2.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LKLMECAK_02332 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
LKLMECAK_02333 3.1e-50 yflH S Protein of unknown function (DUF3243)
LKLMECAK_02334 7e-19 yflI
LKLMECAK_02335 1.5e-14 yflJ S Protein of unknown function (DUF2639)
LKLMECAK_02336 1.3e-122 yflK S protein conserved in bacteria
LKLMECAK_02337 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LKLMECAK_02338 6.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LKLMECAK_02339 4.8e-148 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
LKLMECAK_02340 3.6e-225 citM C Citrate transporter
LKLMECAK_02341 4.6e-177 yflP S Tripartite tricarboxylate transporter family receptor
LKLMECAK_02342 2.6e-118 citT T response regulator
LKLMECAK_02343 6.2e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LKLMECAK_02344 4.6e-80 srtA 3.4.22.70 M Sortase family
LKLMECAK_02345 0.0 M1-568 M cell wall anchor domain
LKLMECAK_02346 2.8e-151 M1-574 T Transcriptional regulatory protein, C terminal
LKLMECAK_02347 0.0 ywpD T PhoQ Sensor
LKLMECAK_02348 2.5e-73 M1-820 Q Collagen triple helix repeat (20 copies)
LKLMECAK_02350 5.9e-27 Q PFAM Collagen triple helix
LKLMECAK_02351 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
LKLMECAK_02352 1.7e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
LKLMECAK_02353 1.3e-57 yflT S Heat induced stress protein YflT
LKLMECAK_02354 2.7e-24 S Protein of unknown function (DUF3212)
LKLMECAK_02355 7.9e-188 yfmJ S N-terminal domain of oxidoreductase
LKLMECAK_02356 1.1e-43 yfmK 2.3.1.128 K acetyltransferase
LKLMECAK_02357 5.7e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
LKLMECAK_02358 3.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKLMECAK_02359 2.6e-206 yfmO EGP Major facilitator Superfamily
LKLMECAK_02360 1.8e-69 yfmP K transcriptional
LKLMECAK_02361 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKLMECAK_02362 2.3e-206 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKLMECAK_02363 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
LKLMECAK_02364 7.5e-107 yfmS NT chemotaxis protein
LKLMECAK_02365 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKLMECAK_02366 3e-246 yfnA E amino acid
LKLMECAK_02367 6.8e-218 fsr P COG0477 Permeases of the major facilitator superfamily
LKLMECAK_02368 6.9e-186 yfnD M Nucleotide-diphospho-sugar transferase
LKLMECAK_02369 6.2e-221 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
LKLMECAK_02370 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
LKLMECAK_02371 2.4e-172 yfnG 4.2.1.45 M dehydratase
LKLMECAK_02372 6.7e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
LKLMECAK_02373 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LKLMECAK_02374 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LKLMECAK_02375 3.4e-197 yetN S Protein of unknown function (DUF3900)
LKLMECAK_02376 5.4e-206 yetM CH FAD binding domain
LKLMECAK_02377 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
LKLMECAK_02379 2.4e-105 yetJ S Belongs to the BI1 family
LKLMECAK_02380 5.3e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
LKLMECAK_02381 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
LKLMECAK_02382 3.7e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKLMECAK_02383 3.4e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKLMECAK_02384 1.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LKLMECAK_02385 2.1e-120 yetF S membrane
LKLMECAK_02387 2e-94 yesJ K Acetyltransferase (GNAT) family
LKLMECAK_02388 8.9e-104 cotJC P Spore Coat
LKLMECAK_02389 1.3e-44 cotJB S CotJB protein
LKLMECAK_02390 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
LKLMECAK_02391 9e-108 aadK G Streptomycin adenylyltransferase
LKLMECAK_02393 9.4e-127 yeeN K transcriptional regulatory protein
LKLMECAK_02394 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
LKLMECAK_02395 4.8e-79 S Protein of unknown function, DUF600
LKLMECAK_02396 1e-40 S Protein of unknown function, DUF600
LKLMECAK_02397 4e-46 S Protein of unknown function, DUF600
LKLMECAK_02398 2.1e-50 S Protein of unknown function, DUF600
LKLMECAK_02399 1.3e-60 S Protein of unknown function, DUF600
LKLMECAK_02400 2.2e-138 cylB V ABC-2 type transporter
LKLMECAK_02401 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
LKLMECAK_02402 8.1e-311 L Uncharacterized conserved protein (DUF2075)
LKLMECAK_02403 2.4e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKLMECAK_02404 1.1e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LKLMECAK_02405 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LKLMECAK_02406 7.9e-149 yerO K Transcriptional regulator
LKLMECAK_02407 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKLMECAK_02408 3e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LKLMECAK_02409 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKLMECAK_02410 1.4e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKLMECAK_02411 1.3e-120 sapB S MgtC SapB transporter
LKLMECAK_02412 7.5e-191 yerI S homoserine kinase type II (protein kinase fold)
LKLMECAK_02413 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
LKLMECAK_02414 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LKLMECAK_02415 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LKLMECAK_02416 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LKLMECAK_02417 4.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
LKLMECAK_02418 2.4e-50 yerC S protein conserved in bacteria
LKLMECAK_02419 1.5e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
LKLMECAK_02420 0.0 yerA 3.5.4.2 F adenine deaminase
LKLMECAK_02421 2.6e-25 S Protein of unknown function (DUF2892)
LKLMECAK_02422 4.5e-233 purD 6.3.4.13 F Belongs to the GARS family
LKLMECAK_02423 3.9e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LKLMECAK_02424 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LKLMECAK_02425 1.9e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LKLMECAK_02426 1.2e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LKLMECAK_02427 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKLMECAK_02428 4.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKLMECAK_02429 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKLMECAK_02430 3.8e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LKLMECAK_02431 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LKLMECAK_02432 1.8e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LKLMECAK_02433 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LKLMECAK_02434 5.5e-29 yebG S NETI protein
LKLMECAK_02435 7.5e-92 yebE S UPF0316 protein
LKLMECAK_02437 1.5e-125 yebC M Membrane
LKLMECAK_02438 8.1e-209 pbuG S permease
LKLMECAK_02439 2.8e-247 S Domain of unknown function (DUF4179)
LKLMECAK_02440 1.9e-92 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LKLMECAK_02441 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LKLMECAK_02442 0.0 yebA E COG1305 Transglutaminase-like enzymes
LKLMECAK_02443 1.9e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LKLMECAK_02444 6.6e-176 yeaC S COG0714 MoxR-like ATPases
LKLMECAK_02445 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
LKLMECAK_02446 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
LKLMECAK_02447 7.2e-35 ydjO S Cold-inducible protein YdjO
LKLMECAK_02449 1.5e-133 ydjN U Involved in the tonB-independent uptake of proteins
LKLMECAK_02450 1.2e-61 ydjM M Lytic transglycolase
LKLMECAK_02451 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
LKLMECAK_02452 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LKLMECAK_02453 1.4e-145 rsiV S Protein of unknown function (DUF3298)
LKLMECAK_02454 0.0 yrhL I Acyltransferase family
LKLMECAK_02455 4.1e-144 ydjI S virion core protein (lumpy skin disease virus)
LKLMECAK_02456 3.8e-118 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
LKLMECAK_02457 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LKLMECAK_02458 3.3e-113 pspA KT Phage shock protein A
LKLMECAK_02459 3.6e-30 yjdJ S Domain of unknown function (DUF4306)
LKLMECAK_02460 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
LKLMECAK_02461 1.1e-248 gutA G MFS/sugar transport protein
LKLMECAK_02462 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
LKLMECAK_02463 0.0 K NB-ARC domain
LKLMECAK_02464 2.8e-17
LKLMECAK_02465 2e-79 S NYN domain
LKLMECAK_02466 2.3e-74 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKLMECAK_02467 2.2e-59 S Pfam:Phage_holin_4_1
LKLMECAK_02472 3.2e-225 S peptidoglycan catabolic process
LKLMECAK_02473 1e-46
LKLMECAK_02474 1.6e-132
LKLMECAK_02475 3.3e-25 S Phage tail assembly chaperone protein, TAC
LKLMECAK_02476 7.2e-09 chiA 3.2.1.14 GH18 G Belongs to the glycosyl hydrolase 18 family
LKLMECAK_02477 3.4e-33 N Bacterial Ig-like domain 2
LKLMECAK_02478 7.7e-30 S Protein of unknown function (DUF3168)
LKLMECAK_02479 6.2e-38 S Bacteriophage HK97-gp10, putative tail-component
LKLMECAK_02480 4.3e-29 S Phage head-tail joining protein
LKLMECAK_02481 2.3e-37 S Phage gp6-like head-tail connector protein
LKLMECAK_02484 2e-145 S Phage capsid family
LKLMECAK_02485 3e-59 S Domain of unknown function (DUF4355)
LKLMECAK_02486 4.3e-92 S Phage Mu protein F like protein
LKLMECAK_02487 1.8e-198 S Phage portal protein, SPP1 Gp6-like
LKLMECAK_02488 7.5e-185 ps334 S Terminase-like family
LKLMECAK_02489 1.5e-82 yqaS L DNA packaging
LKLMECAK_02492 3.9e-12 K Transcriptional regulator
LKLMECAK_02494 2.1e-67 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LKLMECAK_02498 8.4e-46
LKLMECAK_02500 5.5e-71
LKLMECAK_02501 2.4e-105 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
LKLMECAK_02505 1.5e-16 yqaO S Phage-like element PBSX protein XtrA
LKLMECAK_02507 5e-59 rusA L Endodeoxyribonuclease RusA
LKLMECAK_02509 5.5e-122 xkdC L IstB-like ATP binding protein
LKLMECAK_02510 9.6e-76 3.1.3.16 L DnaD domain protein
LKLMECAK_02512 5.8e-69 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
LKLMECAK_02513 1.2e-99
LKLMECAK_02517 4.2e-85
LKLMECAK_02518 4.3e-61 S DNA binding
LKLMECAK_02519 5e-32
LKLMECAK_02520 6.2e-22
LKLMECAK_02522 4.1e-20 K Helix-turn-helix XRE-family like proteins
LKLMECAK_02523 2.3e-44 xre K Helix-turn-helix XRE-family like proteins
LKLMECAK_02524 4.5e-25 S Short C-terminal domain
LKLMECAK_02525 2.8e-45 xkdA E IrrE N-terminal-like domain
LKLMECAK_02526 9.9e-145 L Belongs to the 'phage' integrase family
LKLMECAK_02527 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LKLMECAK_02528 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LKLMECAK_02529 4.3e-127 ydiL S CAAX protease self-immunity
LKLMECAK_02530 1.7e-27 ydiK S Domain of unknown function (DUF4305)
LKLMECAK_02531 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LKLMECAK_02532 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LKLMECAK_02533 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LKLMECAK_02534 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LKLMECAK_02535 0.0 ydiF S ABC transporter
LKLMECAK_02536 8.1e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LKLMECAK_02537 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LKLMECAK_02538 4.6e-123 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
LKLMECAK_02539 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
LKLMECAK_02540 1.3e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LKLMECAK_02542 7.8e-08
LKLMECAK_02547 7.8e-08
LKLMECAK_02555 1.6e-08
LKLMECAK_02559 9e-21 C Na+/H+ antiporter family
LKLMECAK_02560 2.4e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
LKLMECAK_02561 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LKLMECAK_02562 1.8e-265 ygaK C Berberine and berberine like
LKLMECAK_02564 2.8e-230 oppA5 E PFAM extracellular solute-binding protein family 5
LKLMECAK_02565 5.4e-138 appB P Binding-protein-dependent transport system inner membrane component
LKLMECAK_02566 1.7e-125 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKLMECAK_02567 1.3e-134 oppD3 P Belongs to the ABC transporter superfamily
LKLMECAK_02568 4e-133 oppF3 E Belongs to the ABC transporter superfamily
LKLMECAK_02569 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LKLMECAK_02570 7.3e-180 S Amidohydrolase
LKLMECAK_02571 1.6e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LKLMECAK_02572 4.4e-167 ssuA M Sulfonate ABC transporter
LKLMECAK_02573 7e-142 ssuC P ABC transporter (permease)
LKLMECAK_02574 2.5e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
LKLMECAK_02575 1.6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKLMECAK_02576 8.6e-81 ygaO
LKLMECAK_02577 4.8e-23 K Transcriptional regulator
LKLMECAK_02579 9.4e-107 yhzB S B3/4 domain
LKLMECAK_02580 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LKLMECAK_02581 1.4e-173 yhbB S Putative amidase domain
LKLMECAK_02582 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LKLMECAK_02583 3e-108 yhbD K Protein of unknown function (DUF4004)
LKLMECAK_02584 8.9e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
LKLMECAK_02585 1e-61 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
LKLMECAK_02587 0.0 prkA T Ser protein kinase
LKLMECAK_02588 3.9e-215 yhbH S Belongs to the UPF0229 family
LKLMECAK_02589 4.6e-74 yhbI K DNA-binding transcription factor activity
LKLMECAK_02590 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
LKLMECAK_02591 8.4e-285 yhcA EGP Major facilitator Superfamily
LKLMECAK_02592 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
LKLMECAK_02593 3.8e-55 yhcC
LKLMECAK_02594 8.1e-52
LKLMECAK_02595 2.8e-61 yhcF K Transcriptional regulator
LKLMECAK_02596 1.3e-123 yhcG V ABC transporter, ATP-binding protein
LKLMECAK_02597 3.4e-166 yhcH V ABC transporter, ATP-binding protein
LKLMECAK_02598 8.2e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LKLMECAK_02599 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
LKLMECAK_02600 1.7e-143 metQ M Belongs to the nlpA lipoprotein family
LKLMECAK_02601 2.5e-184 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
LKLMECAK_02602 1.5e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKLMECAK_02603 6.5e-54 yhcM
LKLMECAK_02604 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKLMECAK_02605 1.4e-159 yhcP
LKLMECAK_02606 8.4e-114 yhcQ M Spore coat protein
LKLMECAK_02607 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
LKLMECAK_02608 1.7e-105 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LKLMECAK_02609 4e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LKLMECAK_02610 1.3e-69 yhcU S Family of unknown function (DUF5365)
LKLMECAK_02611 9.9e-68 yhcV S COG0517 FOG CBS domain
LKLMECAK_02612 1.1e-124 yhcW 5.4.2.6 S hydrolase
LKLMECAK_02613 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LKLMECAK_02614 2.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKLMECAK_02615 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LKLMECAK_02616 7.7e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
LKLMECAK_02617 1.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LKLMECAK_02618 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LKLMECAK_02619 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LKLMECAK_02620 8.5e-70 yhcY 2.7.13.3 T Histidine kinase
LKLMECAK_02621 1.6e-36 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKLMECAK_02622 4.3e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
LKLMECAK_02623 2.5e-39 yhdB S YhdB-like protein
LKLMECAK_02624 1.1e-53 yhdC S Protein of unknown function (DUF3889)
LKLMECAK_02625 5.4e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LKLMECAK_02626 1.6e-73 nsrR K Transcriptional regulator
LKLMECAK_02627 3.1e-244 ygxB M Conserved TM helix
LKLMECAK_02628 1.8e-270 ycgB S Stage V sporulation protein R
LKLMECAK_02629 1.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LKLMECAK_02630 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LKLMECAK_02631 1.3e-162 citR K Transcriptional regulator
LKLMECAK_02632 1.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
LKLMECAK_02633 8.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKLMECAK_02634 1.2e-250 yhdG E amino acid
LKLMECAK_02635 2.9e-198 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LKLMECAK_02636 8.1e-45 yhdK S Sigma-M inhibitor protein
LKLMECAK_02637 1.3e-201 yhdL S Sigma factor regulator N-terminal
LKLMECAK_02638 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
LKLMECAK_02639 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LKLMECAK_02640 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LKLMECAK_02641 2.8e-70 cueR K transcriptional
LKLMECAK_02642 1.9e-225 yhdR 2.6.1.1 E Aminotransferase
LKLMECAK_02643 4.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKLMECAK_02644 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
LKLMECAK_02645 3.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKLMECAK_02646 1.9e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKLMECAK_02647 7.2e-127 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LKLMECAK_02649 3.5e-205 yhdY M Mechanosensitive ion channel
LKLMECAK_02650 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LKLMECAK_02651 1.1e-155 yheN G deacetylase
LKLMECAK_02652 9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LKLMECAK_02653 3e-87 pksA K Transcriptional regulator
LKLMECAK_02654 4e-93 ymcC S Membrane
LKLMECAK_02655 3.1e-84 T universal stress protein
LKLMECAK_02657 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
LKLMECAK_02658 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
LKLMECAK_02659 1.6e-111 yheG GM NAD(P)H-binding
LKLMECAK_02661 1.3e-28 sspB S spore protein
LKLMECAK_02662 2.2e-36 yheE S Family of unknown function (DUF5342)
LKLMECAK_02663 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
LKLMECAK_02664 1.7e-212 yheC HJ YheC/D like ATP-grasp
LKLMECAK_02665 3.6e-205 yheB S Belongs to the UPF0754 family
LKLMECAK_02666 4.4e-53 yheA S Belongs to the UPF0342 family
LKLMECAK_02667 5.9e-200 yhaZ L DNA alkylation repair enzyme
LKLMECAK_02668 4.7e-157 yhaX S haloacid dehalogenase-like hydrolase
LKLMECAK_02669 2.7e-293 hemZ H coproporphyrinogen III oxidase
LKLMECAK_02670 7.8e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
LKLMECAK_02671 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
LKLMECAK_02672 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
LKLMECAK_02674 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
LKLMECAK_02675 1.1e-13 S YhzD-like protein
LKLMECAK_02676 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
LKLMECAK_02677 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
LKLMECAK_02678 4.7e-235 yhaO L DNA repair exonuclease
LKLMECAK_02679 0.0 yhaN L AAA domain
LKLMECAK_02680 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
LKLMECAK_02681 1.8e-31 yhaL S Sporulation protein YhaL
LKLMECAK_02682 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LKLMECAK_02683 7e-95 yhaK S Putative zincin peptidase
LKLMECAK_02684 9.9e-55 yhaI S Protein of unknown function (DUF1878)
LKLMECAK_02685 8.6e-113 hpr K Negative regulator of protease production and sporulation
LKLMECAK_02686 6.2e-39 yhaH S YtxH-like protein
LKLMECAK_02687 2e-17
LKLMECAK_02688 1.4e-76 trpP S Tryptophan transporter TrpP
LKLMECAK_02689 2.3e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LKLMECAK_02690 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LKLMECAK_02691 1.1e-135 ecsA V transporter (ATP-binding protein)
LKLMECAK_02692 4.2e-220 ecsB U ABC transporter
LKLMECAK_02693 4e-122 ecsC S EcsC protein family
LKLMECAK_02694 2e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LKLMECAK_02695 6.2e-244 yhfA C membrane
LKLMECAK_02696 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LKLMECAK_02697 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LKLMECAK_02698 9.5e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LKLMECAK_02699 9.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LKLMECAK_02700 1.6e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LKLMECAK_02701 3.2e-101 yhgD K Transcriptional regulator
LKLMECAK_02702 7.2e-245 yhgE S YhgE Pip N-terminal domain protein
LKLMECAK_02703 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKLMECAK_02705 8.6e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
LKLMECAK_02706 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKLMECAK_02707 7.9e-11 yhfH S YhfH-like protein
LKLMECAK_02708 2.2e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LKLMECAK_02709 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
LKLMECAK_02710 2.7e-109 yhfK GM NmrA-like family
LKLMECAK_02711 4.1e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LKLMECAK_02712 1.5e-62 yhfM
LKLMECAK_02713 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
LKLMECAK_02714 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
LKLMECAK_02715 1.5e-150 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LKLMECAK_02716 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
LKLMECAK_02717 4.3e-200 vraB 2.3.1.9 I Belongs to the thiolase family
LKLMECAK_02718 1.4e-278 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LKLMECAK_02719 3.5e-89 bioY S BioY family
LKLMECAK_02720 3.1e-197 hemAT NT chemotaxis protein
LKLMECAK_02721 3.5e-296 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LKLMECAK_02722 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKLMECAK_02723 5.4e-31 yhzC S IDEAL
LKLMECAK_02724 1.9e-109 comK K Competence transcription factor
LKLMECAK_02725 4.7e-66 frataxin S Domain of unknown function (DU1801)
LKLMECAK_02726 4.2e-62 frataxin S Domain of unknown function (DU1801)
LKLMECAK_02727 1.9e-124 yrpD S Domain of unknown function, YrpD
LKLMECAK_02728 1.6e-42 yhjA S Excalibur calcium-binding domain
LKLMECAK_02729 3.3e-47 S Belongs to the UPF0145 family
LKLMECAK_02730 5e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKLMECAK_02731 3.1e-27 yhjC S Protein of unknown function (DUF3311)
LKLMECAK_02732 1.7e-60 yhjD
LKLMECAK_02733 7.7e-109 yhjE S SNARE associated Golgi protein
LKLMECAK_02734 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
LKLMECAK_02736 2.1e-269 yhjG CH FAD binding domain
LKLMECAK_02737 8.4e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
LKLMECAK_02738 1.2e-187 abrB S membrane
LKLMECAK_02739 3e-202 blt EGP Major facilitator Superfamily
LKLMECAK_02740 1.1e-107 K QacR-like protein, C-terminal region
LKLMECAK_02741 6.3e-93 yhjR S Rubrerythrin
LKLMECAK_02742 2.5e-119 ydfS S Protein of unknown function (DUF421)
LKLMECAK_02743 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
LKLMECAK_02744 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LKLMECAK_02745 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LKLMECAK_02746 0.0 sbcC L COG0419 ATPase involved in DNA repair
LKLMECAK_02747 5e-50 yisB V COG1403 Restriction endonuclease
LKLMECAK_02748 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
LKLMECAK_02749 1.1e-63 gerPE S Spore germination protein GerPE
LKLMECAK_02750 3.1e-23 gerPD S Spore germination protein
LKLMECAK_02751 1.4e-62 gerPC S Spore germination protein
LKLMECAK_02752 1.8e-34 gerPB S cell differentiation
LKLMECAK_02753 8.4e-34 gerPA S Spore germination protein
LKLMECAK_02754 4.8e-07 yisI S Spo0E like sporulation regulatory protein
LKLMECAK_02755 7.8e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LKLMECAK_02756 3.2e-59 yisL S UPF0344 protein
LKLMECAK_02757 3.4e-97 yisN S Protein of unknown function (DUF2777)
LKLMECAK_02758 0.0 asnO 6.3.5.4 E Asparagine synthase
LKLMECAK_02759 3.6e-129 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
LKLMECAK_02760 4.2e-245 yisQ V Mate efflux family protein
LKLMECAK_02761 2.3e-159 yisR K Transcriptional regulator
LKLMECAK_02762 9.2e-144 purR K helix_turn _helix lactose operon repressor
LKLMECAK_02763 5.8e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
LKLMECAK_02764 3.1e-81 yisT S DinB family
LKLMECAK_02765 1.6e-69 mcbG S Pentapeptide repeats (9 copies)
LKLMECAK_02766 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
LKLMECAK_02767 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LKLMECAK_02768 6.6e-55 yajQ S Belongs to the UPF0234 family
LKLMECAK_02769 7.6e-160 cvfB S protein conserved in bacteria
LKLMECAK_02770 1.1e-170 yufN S ABC transporter substrate-binding protein PnrA-like
LKLMECAK_02771 7.4e-110 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LKLMECAK_02773 1.3e-156 yitS S protein conserved in bacteria
LKLMECAK_02774 2.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
LKLMECAK_02775 1.2e-79 ipi S Intracellular proteinase inhibitor
LKLMECAK_02776 4.4e-26 S Protein of unknown function (DUF3813)
LKLMECAK_02777 3.5e-07
LKLMECAK_02778 5.1e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LKLMECAK_02779 9e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
LKLMECAK_02780 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
LKLMECAK_02781 4.6e-73 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LKLMECAK_02782 1.5e-272 yitY C D-arabinono-1,4-lactone oxidase
LKLMECAK_02783 1.2e-89 norB G Major Facilitator Superfamily
LKLMECAK_02784 1.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LKLMECAK_02785 1.5e-225 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LKLMECAK_02786 1.1e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
LKLMECAK_02787 1.9e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LKLMECAK_02788 6.5e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LKLMECAK_02789 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
LKLMECAK_02790 8.7e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LKLMECAK_02791 1.2e-27 yjzC S YjzC-like protein
LKLMECAK_02792 3.3e-23 yjzD S Protein of unknown function (DUF2929)
LKLMECAK_02793 8.4e-139 yjaU I carboxylic ester hydrolase activity
LKLMECAK_02794 1.7e-102 yjaV
LKLMECAK_02795 2.7e-165 med S Transcriptional activator protein med
LKLMECAK_02796 1.1e-26 comZ S ComZ
LKLMECAK_02797 1e-31 yjzB
LKLMECAK_02798 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKLMECAK_02799 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKLMECAK_02800 5.6e-149 yjaZ O Zn-dependent protease
LKLMECAK_02801 4.8e-182 appD P Belongs to the ABC transporter superfamily
LKLMECAK_02802 5.9e-188 appF E Belongs to the ABC transporter superfamily
LKLMECAK_02803 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
LKLMECAK_02804 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKLMECAK_02805 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKLMECAK_02806 4.7e-145 yjbA S Belongs to the UPF0736 family
LKLMECAK_02807 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LKLMECAK_02808 0.0 oppA E ABC transporter substrate-binding protein
LKLMECAK_02809 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKLMECAK_02810 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKLMECAK_02811 2.7e-202 oppD P Belongs to the ABC transporter superfamily
LKLMECAK_02812 2.3e-170 oppF E Belongs to the ABC transporter superfamily
LKLMECAK_02813 9.8e-230 S Putative glycosyl hydrolase domain
LKLMECAK_02814 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKLMECAK_02815 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LKLMECAK_02816 4.7e-109 yjbE P Integral membrane protein TerC family
LKLMECAK_02817 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LKLMECAK_02818 2.3e-215 yjbF S Competence protein
LKLMECAK_02819 0.0 pepF E oligoendopeptidase F
LKLMECAK_02820 5.8e-19
LKLMECAK_02821 6.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LKLMECAK_02822 4.8e-72 yjbI S Bacterial-like globin
LKLMECAK_02823 1.2e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LKLMECAK_02824 1.5e-95 yjbK S protein conserved in bacteria
LKLMECAK_02825 8.6e-60 yjbL S Belongs to the UPF0738 family
LKLMECAK_02826 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
LKLMECAK_02827 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LKLMECAK_02828 4.1e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LKLMECAK_02829 1.2e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LKLMECAK_02830 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LKLMECAK_02831 9.9e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LKLMECAK_02832 3.5e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
LKLMECAK_02833 2.8e-210 thiO 1.4.3.19 E Glycine oxidase
LKLMECAK_02834 6.7e-30 thiS H Thiamine biosynthesis
LKLMECAK_02835 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LKLMECAK_02836 1.1e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LKLMECAK_02837 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LKLMECAK_02838 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LKLMECAK_02839 1.5e-88 yjbX S Spore coat protein
LKLMECAK_02840 6.7e-83 cotZ S Spore coat protein
LKLMECAK_02841 4.6e-93 cotY S Spore coat protein Z
LKLMECAK_02842 5.1e-71 cotX S Spore Coat Protein X and V domain
LKLMECAK_02843 6.8e-21 cotW
LKLMECAK_02844 1.4e-52 cotV S Spore Coat Protein X and V domain
LKLMECAK_02845 5.6e-56 yjcA S Protein of unknown function (DUF1360)
LKLMECAK_02849 3.8e-38 spoVIF S Stage VI sporulation protein F
LKLMECAK_02850 0.0 yjcD 3.6.4.12 L DNA helicase
LKLMECAK_02851 1.3e-35
LKLMECAK_02852 1.4e-141 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
LKLMECAK_02853 5.7e-124 S ABC-2 type transporter
LKLMECAK_02854 6.4e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
LKLMECAK_02855 2.7e-35 K SpoVT / AbrB like domain
LKLMECAK_02857 2.3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKLMECAK_02858 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
LKLMECAK_02859 3.6e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
LKLMECAK_02860 5.6e-211 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LKLMECAK_02861 1.1e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LKLMECAK_02863 2e-22
LKLMECAK_02864 1.1e-256 yobL S Bacterial EndoU nuclease
LKLMECAK_02866 1.5e-57 E Glyoxalase-like domain
LKLMECAK_02867 1.5e-161 bla 3.5.2.6 V beta-lactamase
LKLMECAK_02868 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
LKLMECAK_02869 1.7e-249 yfjF EGP Belongs to the major facilitator superfamily
LKLMECAK_02870 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
LKLMECAK_02871 5e-220 ganA 3.2.1.89 G arabinogalactan
LKLMECAK_02872 7.1e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LKLMECAK_02873 2.1e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LKLMECAK_02874 7.4e-214 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LKLMECAK_02875 1.1e-306 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKLMECAK_02876 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
LKLMECAK_02877 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
LKLMECAK_02878 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
LKLMECAK_02879 1e-122 5.4.2.6 S Haloacid dehalogenase-like hydrolase
LKLMECAK_02880 3.7e-144 N Kelch motif
LKLMECAK_02882 8.1e-106 yhiD S MgtC SapB transporter
LKLMECAK_02884 1.3e-21 yjfB S Putative motility protein
LKLMECAK_02885 2.6e-65 T PhoQ Sensor
LKLMECAK_02886 5.9e-100 yjgB S Domain of unknown function (DUF4309)
LKLMECAK_02887 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
LKLMECAK_02888 4.3e-92 yjgD S Protein of unknown function (DUF1641)
LKLMECAK_02889 4.4e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
LKLMECAK_02890 1.1e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LKLMECAK_02891 6.8e-29
LKLMECAK_02892 1.2e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LKLMECAK_02893 2.1e-124 ybbM S transport system, permease component
LKLMECAK_02894 1e-128 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
LKLMECAK_02895 4.4e-175 yjlA EG Putative multidrug resistance efflux transporter
LKLMECAK_02896 1.8e-89 yjlB S Cupin domain
LKLMECAK_02897 7e-66 yjlC S Protein of unknown function (DUF1641)
LKLMECAK_02898 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
LKLMECAK_02899 3.8e-273 uxaC 5.3.1.12 G glucuronate isomerase
LKLMECAK_02900 2.5e-253 yjmB G symporter YjmB
LKLMECAK_02901 7e-181 exuR K transcriptional
LKLMECAK_02902 5.3e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
LKLMECAK_02903 4e-87 T Transcriptional regulatory protein, C terminal
LKLMECAK_02904 1.4e-131 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LKLMECAK_02905 8.5e-104 V ABC transporter, ATP-binding protein
LKLMECAK_02906 1.4e-64 S ABC-2 family transporter protein
LKLMECAK_02908 2.2e-46 narQ 2.7.13.3 T Histidine kinase
LKLMECAK_02909 5.4e-60 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKLMECAK_02911 8.2e-300 lcnDR2 V Lanthionine synthetase C-like protein
LKLMECAK_02912 2.3e-221 lanT 3.6.3.27 V Peptidase C39 family
LKLMECAK_02915 3.4e-204 salB V Domain of unknown function (DUF4135)
LKLMECAK_02916 1.9e-130 MA20_18170 S membrane transporter protein
LKLMECAK_02917 3.1e-78 yjoA S DinB family
LKLMECAK_02918 4.9e-215 S response regulator aspartate phosphatase
LKLMECAK_02920 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LKLMECAK_02921 8e-61 yjqA S Bacterial PH domain
LKLMECAK_02922 3.9e-110 yjqB S phage-related replication protein
LKLMECAK_02924 2.9e-110 xkdA E IrrE N-terminal-like domain
LKLMECAK_02925 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
LKLMECAK_02927 8.8e-150 xkdC L Bacterial dnaA protein
LKLMECAK_02930 2e-10 yqaO S Phage-like element PBSX protein XtrA
LKLMECAK_02931 3.1e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LKLMECAK_02932 8.9e-110 xtmA L phage terminase small subunit
LKLMECAK_02933 3.6e-209 xtmB S phage terminase, large subunit
LKLMECAK_02934 5.1e-241 yqbA S portal protein
LKLMECAK_02935 9.8e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
LKLMECAK_02936 4.6e-158 xkdG S Phage capsid family
LKLMECAK_02937 3.3e-46 yqbG S Protein of unknown function (DUF3199)
LKLMECAK_02938 5.5e-43 yqbH S Domain of unknown function (DUF3599)
LKLMECAK_02939 4.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
LKLMECAK_02940 3.2e-56 xkdJ
LKLMECAK_02941 8.2e-15
LKLMECAK_02942 7.7e-226 xkdK S Phage tail sheath C-terminal domain
LKLMECAK_02943 2e-74 xkdM S Phage tail tube protein
LKLMECAK_02944 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
LKLMECAK_02945 3.4e-19
LKLMECAK_02946 9.7e-185 xkdO L Transglycosylase SLT domain
LKLMECAK_02947 6.6e-111 xkdP S Lysin motif
LKLMECAK_02948 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
LKLMECAK_02949 7.2e-32 xkdR S Protein of unknown function (DUF2577)
LKLMECAK_02950 4.2e-58 xkdS S Protein of unknown function (DUF2634)
LKLMECAK_02951 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LKLMECAK_02952 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
LKLMECAK_02953 1.2e-26
LKLMECAK_02954 6.4e-91
LKLMECAK_02956 1.6e-28 xkdX
LKLMECAK_02957 8.1e-137 xepA
LKLMECAK_02958 9.6e-37 xhlA S Haemolysin XhlA
LKLMECAK_02959 1.3e-38 xhlB S SPP1 phage holin
LKLMECAK_02960 1.6e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKLMECAK_02961 8.7e-23 spoIISB S Stage II sporulation protein SB
LKLMECAK_02962 5.9e-132 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
LKLMECAK_02963 5.8e-175 pit P phosphate transporter
LKLMECAK_02964 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
LKLMECAK_02965 1.1e-242 steT E amino acid
LKLMECAK_02966 8.2e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
LKLMECAK_02967 4.7e-299 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LKLMECAK_02968 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKLMECAK_02969 1.5e-16 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LKLMECAK_02970 1e-203 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKLMECAK_02971 3.3e-278 yubD P Major Facilitator Superfamily
LKLMECAK_02972 9.3e-155 dppA E D-aminopeptidase
LKLMECAK_02973 5.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKLMECAK_02974 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKLMECAK_02975 1.6e-188 dppD P Belongs to the ABC transporter superfamily
LKLMECAK_02976 0.0 dppE E ABC transporter substrate-binding protein
LKLMECAK_02977 3.7e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LKLMECAK_02978 5.9e-197 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LKLMECAK_02979 8.6e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LKLMECAK_02980 1.6e-182 ykfD E Belongs to the ABC transporter superfamily
LKLMECAK_02981 1.5e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
LKLMECAK_02982 5.5e-158 ykgA E Amidinotransferase
LKLMECAK_02983 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
LKLMECAK_02984 1.1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LKLMECAK_02985 1.4e-51 ykkC P Multidrug resistance protein
LKLMECAK_02986 2.9e-48 ykkD P Multidrug resistance protein
LKLMECAK_02987 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LKLMECAK_02988 1.1e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LKLMECAK_02989 7.6e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LKLMECAK_02990 4.1e-69 ohrA O Organic hydroperoxide resistance protein
LKLMECAK_02991 1.1e-72 ohrR K COG1846 Transcriptional regulators
LKLMECAK_02992 4.2e-71 ohrB O Organic hydroperoxide resistance protein
LKLMECAK_02993 1e-54 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LKLMECAK_02995 3.8e-215 M Glycosyl transferase family 2
LKLMECAK_02996 9.3e-123 M PFAM Collagen triple helix repeat (20 copies)
LKLMECAK_02997 2.6e-214 hcaT 1.5.1.2 EGP Major facilitator Superfamily
LKLMECAK_02998 5.8e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LKLMECAK_02999 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LKLMECAK_03000 5e-176 isp O Belongs to the peptidase S8 family
LKLMECAK_03001 4.3e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKLMECAK_03002 1.2e-132 ykoC P Cobalt transport protein
LKLMECAK_03003 9.1e-303 P ABC transporter, ATP-binding protein
LKLMECAK_03004 1.3e-97 ykoE S ABC-type cobalt transport system, permease component
LKLMECAK_03005 7.4e-244 ydhD M Glycosyl hydrolase
LKLMECAK_03007 3.2e-237 mgtE P Acts as a magnesium transporter
LKLMECAK_03008 5.4e-53 tnrA K transcriptional
LKLMECAK_03009 1.9e-16
LKLMECAK_03010 3.1e-26 ykoL
LKLMECAK_03011 1.1e-80 ykoM K transcriptional
LKLMECAK_03012 6.4e-99 ykoP G polysaccharide deacetylase
LKLMECAK_03013 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
LKLMECAK_03014 4.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LKLMECAK_03015 8.6e-99 ykoX S membrane-associated protein
LKLMECAK_03016 8.6e-134 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LKLMECAK_03017 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKLMECAK_03018 1.5e-118 rsgI S Anti-sigma factor N-terminus
LKLMECAK_03019 2.5e-26 sspD S small acid-soluble spore protein
LKLMECAK_03020 8.6e-125 ykrK S Domain of unknown function (DUF1836)
LKLMECAK_03021 4.5e-155 htpX O Belongs to the peptidase M48B family
LKLMECAK_03022 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
LKLMECAK_03023 7.2e-113 ydfR S Protein of unknown function (DUF421)
LKLMECAK_03024 8.7e-23 ykzE
LKLMECAK_03025 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
LKLMECAK_03026 0.0 kinE 2.7.13.3 T Histidine kinase
LKLMECAK_03027 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKLMECAK_03029 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LKLMECAK_03030 4.2e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LKLMECAK_03031 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LKLMECAK_03032 1.6e-227 mtnE 2.6.1.83 E Aminotransferase
LKLMECAK_03033 5.1e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LKLMECAK_03034 4.7e-128 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LKLMECAK_03035 1.5e-112 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LKLMECAK_03036 7.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LKLMECAK_03037 3.4e-10 S Spo0E like sporulation regulatory protein
LKLMECAK_03038 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
LKLMECAK_03039 5.5e-77 ykvE K transcriptional
LKLMECAK_03040 2.7e-127 motB N Flagellar motor protein
LKLMECAK_03041 3.3e-136 motA N flagellar motor
LKLMECAK_03042 0.0 clpE O Belongs to the ClpA ClpB family
LKLMECAK_03043 1.3e-182 ykvI S membrane
LKLMECAK_03044 5e-183
LKLMECAK_03045 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LKLMECAK_03046 1.7e-78 queD 4.1.2.50, 4.2.3.12 H synthase
LKLMECAK_03047 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LKLMECAK_03048 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LKLMECAK_03049 3.8e-44 ykvR S Protein of unknown function (DUF3219)
LKLMECAK_03050 7.8e-25 ykvS S protein conserved in bacteria
LKLMECAK_03051 3.9e-27
LKLMECAK_03052 9.1e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
LKLMECAK_03053 4e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKLMECAK_03054 1.7e-87 stoA CO thiol-disulfide
LKLMECAK_03055 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LKLMECAK_03056 3.4e-205 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LKLMECAK_03058 7.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
LKLMECAK_03059 8.7e-156 glcT K antiterminator
LKLMECAK_03060 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKLMECAK_03061 2.1e-39 ptsH G phosphocarrier protein HPr
LKLMECAK_03062 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LKLMECAK_03063 6.1e-38 splA S Transcriptional regulator
LKLMECAK_03064 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
LKLMECAK_03065 2.4e-257 mcpC NT chemotaxis protein
LKLMECAK_03066 2.1e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LKLMECAK_03067 1.5e-114 ykwD J protein with SCP PR1 domains
LKLMECAK_03068 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
LKLMECAK_03069 1.3e-254 pilS 2.7.13.3 T PAS fold
LKLMECAK_03070 1.2e-63 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
LKLMECAK_03071 3.9e-215 patA 2.6.1.1 E Aminotransferase
LKLMECAK_03072 2.3e-09
LKLMECAK_03073 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
LKLMECAK_03074 1.4e-83 ykyB S YkyB-like protein
LKLMECAK_03075 6.6e-240 ykuC EGP Major facilitator Superfamily
LKLMECAK_03076 1.6e-88 ykuD S protein conserved in bacteria
LKLMECAK_03077 2e-152 ykuE S Metallophosphoesterase
LKLMECAK_03078 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKLMECAK_03080 3.3e-233 ykuI T Diguanylate phosphodiesterase
LKLMECAK_03081 3.9e-37 ykuJ S protein conserved in bacteria
LKLMECAK_03082 1.4e-92 ykuK S Ribonuclease H-like
LKLMECAK_03083 2.1e-25 ykzF S Antirepressor AbbA
LKLMECAK_03084 1e-75 ykuL S CBS domain
LKLMECAK_03085 1.3e-167 ccpC K Transcriptional regulator
LKLMECAK_03086 1.3e-89 fld C Flavodoxin
LKLMECAK_03087 1.4e-164 ykuO
LKLMECAK_03088 3.9e-78 fld C Flavodoxin
LKLMECAK_03089 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LKLMECAK_03090 6.4e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LKLMECAK_03091 4.8e-38 ykuS S Belongs to the UPF0180 family
LKLMECAK_03092 3.7e-140 ykuT M Mechanosensitive ion channel
LKLMECAK_03093 2.2e-76 ykuV CO thiol-disulfide
LKLMECAK_03094 4.5e-98 rok K Repressor of ComK
LKLMECAK_03095 1.8e-160 yknT
LKLMECAK_03096 2.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LKLMECAK_03097 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LKLMECAK_03098 1.7e-243 moeA 2.10.1.1 H molybdopterin
LKLMECAK_03099 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
LKLMECAK_03100 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
LKLMECAK_03101 5.7e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LKLMECAK_03102 7.5e-105 yknW S Yip1 domain
LKLMECAK_03103 6e-168 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LKLMECAK_03104 2e-121 macB V ABC transporter, ATP-binding protein
LKLMECAK_03105 3e-210 yknZ V ABC transporter (permease)
LKLMECAK_03106 1.7e-131 fruR K Transcriptional regulator
LKLMECAK_03107 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
LKLMECAK_03108 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LKLMECAK_03109 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LKLMECAK_03110 1.7e-36 ykoA
LKLMECAK_03111 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKLMECAK_03112 1.7e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKLMECAK_03113 3.6e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LKLMECAK_03114 5.5e-12 S Uncharacterized protein YkpC
LKLMECAK_03115 6.9e-184 mreB D Rod-share determining protein MreBH
LKLMECAK_03116 1.8e-44 abrB K of stationary sporulation gene expression
LKLMECAK_03117 3.4e-244 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
LKLMECAK_03118 1.9e-147 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
LKLMECAK_03119 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
LKLMECAK_03120 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LKLMECAK_03121 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKLMECAK_03122 8.2e-31 ykzG S Belongs to the UPF0356 family
LKLMECAK_03123 7.4e-146 ykrA S hydrolases of the HAD superfamily
LKLMECAK_03124 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKLMECAK_03126 1.6e-101 recN L Putative cell-wall binding lipoprotein
LKLMECAK_03127 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LKLMECAK_03128 0.0 Q Polyketide synthase of type I
LKLMECAK_03129 0.0 Q polyketide synthase
LKLMECAK_03130 0.0 Q Polyketide synthase of type I
LKLMECAK_03131 0.0 Q Polyketide synthase of type I
LKLMECAK_03132 0.0 Q Polyketide synthase of type I
LKLMECAK_03133 0.0 Q Polyketide synthase of type I
LKLMECAK_03134 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
LKLMECAK_03135 3.3e-208 V Beta-lactamase
LKLMECAK_03136 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKLMECAK_03137 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKLMECAK_03138 4.6e-228 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKLMECAK_03139 5.4e-251 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKLMECAK_03140 8.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
LKLMECAK_03141 1e-134 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
LKLMECAK_03142 3.2e-275 speA 4.1.1.19 E Arginine
LKLMECAK_03143 1.6e-42 yktA S Belongs to the UPF0223 family
LKLMECAK_03144 1.8e-118 yktB S Belongs to the UPF0637 family
LKLMECAK_03145 6.3e-24 ykzI
LKLMECAK_03146 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
LKLMECAK_03147 4e-83 ykzC S Acetyltransferase (GNAT) family
LKLMECAK_03148 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
LKLMECAK_03149 2.2e-13 sigC S Putative zinc-finger
LKLMECAK_03150 1.3e-36 ylaE
LKLMECAK_03151 6.7e-24 S Family of unknown function (DUF5325)
LKLMECAK_03152 0.0 typA T GTP-binding protein TypA
LKLMECAK_03153 6.6e-48 ylaH S YlaH-like protein
LKLMECAK_03154 1.4e-33 ylaI S protein conserved in bacteria
LKLMECAK_03155 2.6e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKLMECAK_03156 8.6e-243 phoH T ATPase related to phosphate starvation-inducible protein PhoH
LKLMECAK_03157 9.4e-83 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LKLMECAK_03158 3.9e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
LKLMECAK_03159 8.7e-44 ylaN S Belongs to the UPF0358 family
LKLMECAK_03160 1.9e-212 ftsW D Belongs to the SEDS family
LKLMECAK_03161 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LKLMECAK_03162 2e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LKLMECAK_03163 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LKLMECAK_03164 1.2e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LKLMECAK_03165 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LKLMECAK_03166 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LKLMECAK_03167 1.9e-50 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LKLMECAK_03168 2e-163 ctaG S cytochrome c oxidase
LKLMECAK_03169 3.2e-59 ylbA S YugN-like family
LKLMECAK_03170 2.2e-73 ylbB T COG0517 FOG CBS domain
LKLMECAK_03171 2.3e-198 ylbC S protein with SCP PR1 domains
LKLMECAK_03172 2.1e-54 ylbD S Putative coat protein
LKLMECAK_03173 8.8e-37 ylbE S YlbE-like protein
LKLMECAK_03174 1.2e-71 ylbF S Belongs to the UPF0342 family
LKLMECAK_03175 5.5e-43 ylbG S UPF0298 protein
LKLMECAK_03177 6e-97 rsmD 2.1.1.171 L Methyltransferase
LKLMECAK_03178 9.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LKLMECAK_03179 2.2e-216 ylbJ S Sporulation integral membrane protein YlbJ
LKLMECAK_03180 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
LKLMECAK_03181 1e-187 ylbL T Belongs to the peptidase S16 family
LKLMECAK_03182 7.3e-228 ylbM S Belongs to the UPF0348 family
LKLMECAK_03183 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
LKLMECAK_03184 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LKLMECAK_03185 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LKLMECAK_03186 1.2e-88 ylbP K n-acetyltransferase
LKLMECAK_03187 1.6e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKLMECAK_03188 7.4e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LKLMECAK_03189 1.2e-77 mraZ K Belongs to the MraZ family
LKLMECAK_03190 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LKLMECAK_03191 2.9e-52 ftsL D Essential cell division protein
LKLMECAK_03192 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LKLMECAK_03193 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
LKLMECAK_03194 2.6e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LKLMECAK_03195 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LKLMECAK_03196 6.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LKLMECAK_03197 2.2e-185 spoVE D Belongs to the SEDS family
LKLMECAK_03198 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LKLMECAK_03199 1.8e-167 murB 1.3.1.98 M cell wall formation
LKLMECAK_03200 4.8e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LKLMECAK_03201 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LKLMECAK_03202 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LKLMECAK_03203 0.0 bpr O COG1404 Subtilisin-like serine proteases
LKLMECAK_03204 4.1e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LKLMECAK_03205 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKLMECAK_03206 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKLMECAK_03207 1.2e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LKLMECAK_03208 2.2e-251 argE 3.5.1.16 E Acetylornithine deacetylase
LKLMECAK_03209 2.2e-38 ylmC S sporulation protein
LKLMECAK_03210 6.5e-159 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
LKLMECAK_03211 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LKLMECAK_03212 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LKLMECAK_03213 5.2e-41 yggT S membrane
LKLMECAK_03214 1.6e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
LKLMECAK_03215 8.9e-68 divIVA D Cell division initiation protein
LKLMECAK_03216 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LKLMECAK_03217 1.2e-61 dksA T COG1734 DnaK suppressor protein
LKLMECAK_03218 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LKLMECAK_03219 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LKLMECAK_03220 8e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LKLMECAK_03221 5.2e-232 pyrP F Xanthine uracil
LKLMECAK_03222 5.9e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LKLMECAK_03223 4.7e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LKLMECAK_03224 3.6e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LKLMECAK_03225 0.0 carB 6.3.5.5 F Belongs to the CarB family
LKLMECAK_03226 2.6e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LKLMECAK_03227 1.1e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LKLMECAK_03228 1.2e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LKLMECAK_03229 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LKLMECAK_03231 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LKLMECAK_03232 1.1e-176 cysP P phosphate transporter
LKLMECAK_03233 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LKLMECAK_03234 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
LKLMECAK_03235 3.8e-142 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LKLMECAK_03236 5.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
LKLMECAK_03237 5.1e-76 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
LKLMECAK_03238 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LKLMECAK_03239 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
LKLMECAK_03240 8.5e-154 yloC S stress-induced protein
LKLMECAK_03241 1.5e-40 ylzA S Belongs to the UPF0296 family
LKLMECAK_03242 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LKLMECAK_03243 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LKLMECAK_03244 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LKLMECAK_03245 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LKLMECAK_03246 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKLMECAK_03247 6.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LKLMECAK_03248 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LKLMECAK_03249 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LKLMECAK_03250 3.3e-138 stp 3.1.3.16 T phosphatase
LKLMECAK_03251 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LKLMECAK_03252 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LKLMECAK_03253 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LKLMECAK_03254 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
LKLMECAK_03255 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LKLMECAK_03256 5.5e-59 asp S protein conserved in bacteria
LKLMECAK_03257 1.4e-303 yloV S kinase related to dihydroxyacetone kinase
LKLMECAK_03258 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
LKLMECAK_03259 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
LKLMECAK_03260 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LKLMECAK_03261 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LKLMECAK_03262 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LKLMECAK_03263 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LKLMECAK_03264 4.6e-129 IQ reductase
LKLMECAK_03265 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LKLMECAK_03266 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LKLMECAK_03267 0.0 smc D Required for chromosome condensation and partitioning
LKLMECAK_03268 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LKLMECAK_03269 7.9e-140 S Phosphotransferase enzyme family
LKLMECAK_03270 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LKLMECAK_03271 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LKLMECAK_03272 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LKLMECAK_03273 1.7e-35 ylqC S Belongs to the UPF0109 family
LKLMECAK_03274 1.3e-61 ylqD S YlqD protein
LKLMECAK_03275 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LKLMECAK_03276 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LKLMECAK_03277 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LKLMECAK_03278 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LKLMECAK_03279 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKLMECAK_03280 4.7e-302 ylqG
LKLMECAK_03281 2.5e-43 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
LKLMECAK_03282 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LKLMECAK_03283 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LKLMECAK_03284 1.2e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
LKLMECAK_03285 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKLMECAK_03286 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LKLMECAK_03287 1.6e-171 xerC L tyrosine recombinase XerC
LKLMECAK_03288 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LKLMECAK_03289 4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LKLMECAK_03290 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LKLMECAK_03291 2e-54 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LKLMECAK_03292 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
LKLMECAK_03293 2.5e-31 fliE N Flagellar hook-basal body
LKLMECAK_03294 1.4e-263 fliF N The M ring may be actively involved in energy transduction
LKLMECAK_03295 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LKLMECAK_03296 1.5e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
LKLMECAK_03297 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LKLMECAK_03298 2e-71 fliJ N Flagellar biosynthesis chaperone
LKLMECAK_03299 4.8e-47 ylxF S MgtE intracellular N domain
LKLMECAK_03300 2.3e-203 fliK N Flagellar hook-length control protein
LKLMECAK_03301 4.1e-72 flgD N Flagellar basal body rod modification protein
LKLMECAK_03302 5.7e-138 flgG N Flagellar basal body rod
LKLMECAK_03303 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
LKLMECAK_03304 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LKLMECAK_03305 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LKLMECAK_03306 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
LKLMECAK_03307 2.5e-110 fliZ N Flagellar biosynthesis protein, FliO
LKLMECAK_03308 3.7e-109 fliP N Plays a role in the flagellum-specific transport system
LKLMECAK_03309 2e-37 fliQ N Role in flagellar biosynthesis
LKLMECAK_03310 5.2e-131 fliR N Flagellar biosynthetic protein FliR
LKLMECAK_03311 7.6e-189 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LKLMECAK_03312 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LKLMECAK_03313 2.2e-191 flhF N Flagellar biosynthesis regulator FlhF
LKLMECAK_03314 4.1e-156 flhG D Belongs to the ParA family
LKLMECAK_03315 2.5e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LKLMECAK_03316 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
LKLMECAK_03317 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
LKLMECAK_03318 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LKLMECAK_03319 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LKLMECAK_03320 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKLMECAK_03321 8e-50 ylxL
LKLMECAK_03322 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
LKLMECAK_03323 4.5e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LKLMECAK_03324 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LKLMECAK_03325 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LKLMECAK_03326 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LKLMECAK_03327 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
LKLMECAK_03328 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LKLMECAK_03329 1.5e-233 rasP M zinc metalloprotease
LKLMECAK_03330 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LKLMECAK_03331 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKLMECAK_03332 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
LKLMECAK_03333 5.4e-206 nusA K Participates in both transcription termination and antitermination
LKLMECAK_03334 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
LKLMECAK_03335 1.8e-47 ylxQ J ribosomal protein
LKLMECAK_03336 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LKLMECAK_03337 3.9e-44 ylxP S protein conserved in bacteria
LKLMECAK_03338 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LKLMECAK_03339 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LKLMECAK_03340 6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LKLMECAK_03341 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LKLMECAK_03342 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LKLMECAK_03343 5.7e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
LKLMECAK_03344 1.2e-233 pepR S Belongs to the peptidase M16 family
LKLMECAK_03345 2.6e-42 ymxH S YlmC YmxH family
LKLMECAK_03346 1e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
LKLMECAK_03347 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LKLMECAK_03348 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LKLMECAK_03349 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LKLMECAK_03350 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LKLMECAK_03351 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKLMECAK_03352 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
LKLMECAK_03353 6.3e-31 S YlzJ-like protein
LKLMECAK_03354 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LKLMECAK_03355 4.4e-132 ymfC K Transcriptional regulator
LKLMECAK_03356 3e-227 ymfD EGP Major facilitator Superfamily
LKLMECAK_03357 2.1e-76 K helix_turn_helix multiple antibiotic resistance protein
LKLMECAK_03358 0.0 ydgH S drug exporters of the RND superfamily
LKLMECAK_03359 1.3e-235 ymfF S Peptidase M16
LKLMECAK_03360 3.5e-241 ymfH S zinc protease
LKLMECAK_03361 6.6e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LKLMECAK_03362 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
LKLMECAK_03363 1e-142 ymfK S Protein of unknown function (DUF3388)
LKLMECAK_03364 1.9e-124 ymfM S protein conserved in bacteria
LKLMECAK_03365 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LKLMECAK_03366 1.2e-230 cinA 3.5.1.42 S Belongs to the CinA family
LKLMECAK_03367 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LKLMECAK_03368 3.3e-193 pbpX V Beta-lactamase
LKLMECAK_03369 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
LKLMECAK_03370 4.9e-153 ymdB S protein conserved in bacteria
LKLMECAK_03371 1.2e-36 spoVS S Stage V sporulation protein S
LKLMECAK_03372 2.4e-195 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LKLMECAK_03373 2.6e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LKLMECAK_03374 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LKLMECAK_03375 4.6e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LKLMECAK_03376 1.7e-88 cotE S Spore coat protein
LKLMECAK_03377 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LKLMECAK_03378 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LKLMECAK_03380 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
LKLMECAK_03381 5.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LKLMECAK_03382 1.6e-182 pksD Q Acyl transferase domain
LKLMECAK_03383 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LKLMECAK_03384 5.5e-34 acpK IQ Phosphopantetheine attachment site
LKLMECAK_03385 2.4e-242 pksG 2.3.3.10 I synthase
LKLMECAK_03386 9.1e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
LKLMECAK_03387 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
LKLMECAK_03388 0.0 rhiB IQ polyketide synthase
LKLMECAK_03389 0.0 Q Polyketide synthase of type I
LKLMECAK_03390 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
LKLMECAK_03391 0.0 dhbF IQ polyketide synthase
LKLMECAK_03392 0.0 pks13 HQ Beta-ketoacyl synthase
LKLMECAK_03393 8.4e-229 cypA C Cytochrome P450
LKLMECAK_03394 1.9e-77 nucB M Deoxyribonuclease NucA/NucB
LKLMECAK_03395 3.6e-118 yoaK S Membrane
LKLMECAK_03396 4.1e-62 ymzB
LKLMECAK_03397 1.7e-254 aprX O Belongs to the peptidase S8 family
LKLMECAK_03398 8.7e-125 ymaC S Replication protein
LKLMECAK_03399 6e-79 ymaD O redox protein, regulator of disulfide bond formation
LKLMECAK_03400 2.6e-53 ebrB P Small Multidrug Resistance protein
LKLMECAK_03401 2.6e-47 ebrA P Small Multidrug Resistance protein
LKLMECAK_03403 9.2e-47 ymaF S YmaF family
LKLMECAK_03404 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LKLMECAK_03405 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LKLMECAK_03406 1.8e-41
LKLMECAK_03407 1.8e-20 ymzA
LKLMECAK_03408 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LKLMECAK_03409 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKLMECAK_03410 1.4e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKLMECAK_03411 6.5e-108 ymaB S MutT family
LKLMECAK_03412 1.4e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LKLMECAK_03413 1.3e-176 spoVK O stage V sporulation protein K
LKLMECAK_03414 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LKLMECAK_03415 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LKLMECAK_03416 4.3e-68 glnR K transcriptional
LKLMECAK_03417 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
LKLMECAK_03418 1.7e-207 mrjp G Major royal jelly protein
LKLMECAK_03419 1.9e-248 xynT G MFS/sugar transport protein
LKLMECAK_03420 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
LKLMECAK_03421 1.6e-208 xylR GK ROK family
LKLMECAK_03422 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
LKLMECAK_03423 9.3e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
LKLMECAK_03424 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
LKLMECAK_03428 7.4e-186 adhP 1.1.1.1 C alcohol dehydrogenase
LKLMECAK_03429 1e-09
LKLMECAK_03431 1.7e-142 yoaP 3.1.3.18 K YoaP-like
LKLMECAK_03432 6.3e-99 J Acetyltransferase (GNAT) domain
LKLMECAK_03433 6.6e-116 ynaE S Domain of unknown function (DUF3885)
LKLMECAK_03434 1.1e-200 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKLMECAK_03435 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
LKLMECAK_03438 5.6e-92 yvgO
LKLMECAK_03440 0.0 yobO M Pectate lyase superfamily protein
LKLMECAK_03441 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LKLMECAK_03442 2.6e-141 yndL S Replication protein
LKLMECAK_03443 9.1e-08
LKLMECAK_03444 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
LKLMECAK_03445 1.2e-71 yndM S Protein of unknown function (DUF2512)
LKLMECAK_03446 2.1e-12 yoaW
LKLMECAK_03447 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LKLMECAK_03448 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LKLMECAK_03449 3.5e-112 yneB L resolvase
LKLMECAK_03450 9.8e-33 ynzC S UPF0291 protein
LKLMECAK_03451 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LKLMECAK_03452 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
LKLMECAK_03453 2.3e-28 yneF S UPF0154 protein
LKLMECAK_03454 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
LKLMECAK_03455 1.7e-125 ccdA O cytochrome c biogenesis protein
LKLMECAK_03456 3e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
LKLMECAK_03457 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
LKLMECAK_03458 2.5e-74 yneK S Protein of unknown function (DUF2621)
LKLMECAK_03459 1.1e-62 hspX O Spore coat protein
LKLMECAK_03460 2.3e-19 sspP S Belongs to the SspP family
LKLMECAK_03461 7.5e-15 sspO S Belongs to the SspO family
LKLMECAK_03462 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LKLMECAK_03463 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LKLMECAK_03465 7.1e-18 tlp S Belongs to the Tlp family
LKLMECAK_03466 8.3e-75 yneP S Thioesterase-like superfamily
LKLMECAK_03467 4.1e-52 yneQ
LKLMECAK_03468 1.1e-49 yneR S Belongs to the HesB IscA family
LKLMECAK_03469 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LKLMECAK_03470 1.5e-68 yccU S CoA-binding protein
LKLMECAK_03471 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKLMECAK_03472 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKLMECAK_03473 6e-13
LKLMECAK_03474 5.1e-41 ynfC
LKLMECAK_03475 1.2e-245 agcS E Sodium alanine symporter
LKLMECAK_03476 3.3e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
LKLMECAK_03477 1.3e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
LKLMECAK_03478 1.5e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
LKLMECAK_03479 1.1e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LKLMECAK_03480 2.2e-143 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LKLMECAK_03481 5.1e-179 kdgR_1 K transcriptional
LKLMECAK_03482 2.9e-219 exuT G Sugar (and other) transporter
LKLMECAK_03483 3.5e-154 yndG S DoxX-like family
LKLMECAK_03484 7.3e-80 yndH S Domain of unknown function (DUF4166)
LKLMECAK_03485 7.4e-297 yndJ S YndJ-like protein
LKLMECAK_03486 7.2e-80 S Platelet-activating factor acetylhydrolase, isoform II
LKLMECAK_03487 1.1e-283 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
LKLMECAK_03488 1.2e-49 S Domain of unknown function (DUF4870)
LKLMECAK_03489 2.6e-229 T PhoQ Sensor
LKLMECAK_03490 8.4e-128 T Transcriptional regulatory protein, C terminal
LKLMECAK_03491 2.4e-250 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
LKLMECAK_03492 4.7e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
LKLMECAK_03493 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_03494 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_03495 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_03496 3e-218 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LKLMECAK_03497 1.4e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LKLMECAK_03498 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LKLMECAK_03499 1.3e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LKLMECAK_03500 1.9e-251 yxjC EG COG2610 H gluconate symporter and related permeases
LKLMECAK_03501 5.6e-217 bioI 1.14.14.46 C Cytochrome P450
LKLMECAK_03502 8.2e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LKLMECAK_03503 4.1e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LKLMECAK_03504 2.6e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LKLMECAK_03505 9.6e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LKLMECAK_03506 2e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LKLMECAK_03507 9.6e-68 yngA S membrane
LKLMECAK_03508 2.6e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LKLMECAK_03509 3.2e-104 yngC S SNARE associated Golgi protein
LKLMECAK_03510 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LKLMECAK_03511 3.1e-139 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LKLMECAK_03512 1.3e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
LKLMECAK_03513 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
LKLMECAK_03514 2.1e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
LKLMECAK_03515 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LKLMECAK_03516 3.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
LKLMECAK_03517 1.2e-301 yngK T Glycosyl hydrolase-like 10
LKLMECAK_03518 1.2e-64 yngL S Protein of unknown function (DUF1360)
LKLMECAK_03519 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
LKLMECAK_03520 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_03521 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_03522 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_03523 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
LKLMECAK_03524 3.4e-140 srfAD Q thioesterase
LKLMECAK_03525 3e-248 bamJ E Aminotransferase class I and II
LKLMECAK_03526 6.1e-128 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
LKLMECAK_03527 1.7e-108 yczE S membrane
LKLMECAK_03528 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LKLMECAK_03529 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
LKLMECAK_03530 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LKLMECAK_03531 3.9e-159 bsdA K LysR substrate binding domain
LKLMECAK_03532 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LKLMECAK_03533 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LKLMECAK_03534 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
LKLMECAK_03535 4.8e-76 yclD
LKLMECAK_03536 1.2e-269 dtpT E amino acid peptide transporter
LKLMECAK_03537 9.2e-277 yclG M Pectate lyase superfamily protein
LKLMECAK_03539 7.8e-294 gerKA EG Spore germination protein
LKLMECAK_03540 5.2e-234 gerKC S spore germination
LKLMECAK_03541 1.1e-195 gerKB F Spore germination protein
LKLMECAK_03542 1.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKLMECAK_03543 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKLMECAK_03544 2.1e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
LKLMECAK_03545 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
LKLMECAK_03546 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
LKLMECAK_03547 1.9e-217 yxeP 3.5.1.47 E hydrolase activity
LKLMECAK_03548 3.3e-250 yxeQ S MmgE/PrpD family
LKLMECAK_03549 4e-119 yclH P ABC transporter
LKLMECAK_03550 5.9e-229 yclI V ABC transporter (permease) YclI
LKLMECAK_03551 6.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKLMECAK_03552 4.1e-259 T PhoQ Sensor
LKLMECAK_03553 1.6e-80 S aspartate phosphatase
LKLMECAK_03555 4.5e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
LKLMECAK_03556 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKLMECAK_03557 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKLMECAK_03558 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
LKLMECAK_03559 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
LKLMECAK_03560 6.2e-247 ycnB EGP Major facilitator Superfamily
LKLMECAK_03561 3e-151 ycnC K Transcriptional regulator
LKLMECAK_03562 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
LKLMECAK_03563 1e-44 ycnE S Monooxygenase
LKLMECAK_03564 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
LKLMECAK_03565 7e-259 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKLMECAK_03566 4.2e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKLMECAK_03567 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKLMECAK_03568 3.6e-149 glcU U Glucose uptake
LKLMECAK_03569 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKLMECAK_03570 2.3e-97 ycnI S protein conserved in bacteria
LKLMECAK_03571 3.3e-297 ycnJ P protein, homolog of Cu resistance protein CopC
LKLMECAK_03572 9.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
LKLMECAK_03573 1.6e-55
LKLMECAK_03574 1.8e-225 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
LKLMECAK_03575 8.8e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LKLMECAK_03576 2.4e-206 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
LKLMECAK_03577 1.3e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
LKLMECAK_03579 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LKLMECAK_03580 3.9e-139 ycsF S Belongs to the UPF0271 (lamB) family
LKLMECAK_03581 5.7e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
LKLMECAK_03582 2.5e-149 ycsI S Belongs to the D-glutamate cyclase family
LKLMECAK_03583 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
LKLMECAK_03584 1.2e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
LKLMECAK_03585 1.3e-129 kipR K Transcriptional regulator
LKLMECAK_03586 2.5e-115 ycsK E anatomical structure formation involved in morphogenesis
LKLMECAK_03588 5.1e-56 yczJ S biosynthesis
LKLMECAK_03589 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
LKLMECAK_03590 1.6e-171 ydhF S Oxidoreductase
LKLMECAK_03591 0.0 mtlR K transcriptional regulator, MtlR
LKLMECAK_03592 5.5e-286 ydaB IQ acyl-CoA ligase
LKLMECAK_03593 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKLMECAK_03594 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
LKLMECAK_03595 3.2e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LKLMECAK_03596 1.4e-77 ydaG 1.4.3.5 S general stress protein
LKLMECAK_03597 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LKLMECAK_03598 1.3e-47 ydzA EGP Major facilitator Superfamily
LKLMECAK_03599 4.3e-74 lrpC K Transcriptional regulator
LKLMECAK_03600 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKLMECAK_03601 2.8e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
LKLMECAK_03602 2.5e-147 ydaK T Diguanylate cyclase, GGDEF domain
LKLMECAK_03603 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
LKLMECAK_03604 7.2e-231 ydaM M Glycosyl transferase family group 2
LKLMECAK_03605 0.0 ydaN S Bacterial cellulose synthase subunit
LKLMECAK_03606 0.0 ydaO E amino acid
LKLMECAK_03607 2.8e-73 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LKLMECAK_03608 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LKLMECAK_03609 4.8e-41 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LKLMECAK_03610 2.2e-67
LKLMECAK_03612 1.1e-206 S Histidine kinase
LKLMECAK_03614 6.5e-13
LKLMECAK_03616 2.5e-74
LKLMECAK_03617 1.6e-97
LKLMECAK_03618 1.8e-38
LKLMECAK_03619 2.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
LKLMECAK_03621 6.5e-34 ydaT
LKLMECAK_03622 1.2e-53 yvaE P Small Multidrug Resistance protein
LKLMECAK_03623 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
LKLMECAK_03625 1e-40 ydbB G Cupin domain
LKLMECAK_03626 8.5e-60 ydbC S Domain of unknown function (DUF4937
LKLMECAK_03627 1.2e-154 ydbD P Catalase
LKLMECAK_03628 1.6e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LKLMECAK_03629 1.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LKLMECAK_03630 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
LKLMECAK_03631 5e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKLMECAK_03632 4e-158 ydbI S AI-2E family transporter
LKLMECAK_03633 2.3e-170 ydbJ V ABC transporter, ATP-binding protein
LKLMECAK_03634 3.7e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LKLMECAK_03635 4.6e-52 ydbL
LKLMECAK_03636 6.8e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
LKLMECAK_03637 1.5e-10 S Fur-regulated basic protein B
LKLMECAK_03638 5.8e-09 S Fur-regulated basic protein A
LKLMECAK_03639 3.4e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKLMECAK_03640 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LKLMECAK_03641 2.3e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LKLMECAK_03642 1e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LKLMECAK_03643 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LKLMECAK_03644 1.3e-60 ydbS S Bacterial PH domain
LKLMECAK_03645 7.7e-261 ydbT S Membrane
LKLMECAK_03646 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
LKLMECAK_03647 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LKLMECAK_03648 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
LKLMECAK_03649 2.6e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKLMECAK_03650 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LKLMECAK_03651 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
LKLMECAK_03652 2.3e-145 rsbR T Positive regulator of sigma-B
LKLMECAK_03653 1.8e-57 rsbS T antagonist
LKLMECAK_03654 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LKLMECAK_03655 1.7e-187 rsbU 3.1.3.3 KT phosphatase
LKLMECAK_03656 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
LKLMECAK_03657 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LKLMECAK_03658 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKLMECAK_03659 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
LKLMECAK_03660 0.0 yhgF K COG2183 Transcriptional accessory protein
LKLMECAK_03661 1.7e-14
LKLMECAK_03662 8.6e-59 ydcK S Belongs to the SprT family
LKLMECAK_03670 1.1e-95 ywrO S Flavodoxin-like fold
LKLMECAK_03671 2e-149 S Serine aminopeptidase, S33
LKLMECAK_03672 5.7e-229 proP EGP Transporter
LKLMECAK_03673 1.9e-135 I esterase
LKLMECAK_03674 4.8e-46 ohrB O OsmC-like protein
LKLMECAK_03675 1.4e-48 ohrR K Transcriptional regulator
LKLMECAK_03676 8.3e-23 S Domain of unknown function with cystatin-like fold (DUF4467)
LKLMECAK_03677 1.1e-33 S Domain of unknown function with cystatin-like fold (DUF4467)
LKLMECAK_03678 1e-72 maoC I N-terminal half of MaoC dehydratase
LKLMECAK_03679 3.2e-64 yyaQ S YjbR
LKLMECAK_03680 1.6e-71 ywnA K Transcriptional regulator
LKLMECAK_03681 1.9e-110 ywnB S NAD(P)H-binding
LKLMECAK_03682 1.4e-30 cspL K Cold shock
LKLMECAK_03683 9.2e-40 yrkD S protein conserved in bacteria
LKLMECAK_03684 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
LKLMECAK_03685 5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
LKLMECAK_03686 1.2e-200 yrkH P Rhodanese Homology Domain
LKLMECAK_03687 7.8e-35 yrkI O Belongs to the sulfur carrier protein TusA family
LKLMECAK_03688 1.2e-116 yrkJ S membrane transporter protein
LKLMECAK_03689 3.7e-117 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LKLMECAK_03690 4.1e-101 S Protein of unknown function (DUF2812)
LKLMECAK_03691 4.9e-51 K Transcriptional regulator PadR-like family
LKLMECAK_03692 2.3e-181 S Patatin-like phospholipase
LKLMECAK_03693 5.5e-83 S DinB superfamily
LKLMECAK_03694 5.1e-44 G Cupin domain
LKLMECAK_03697 6.6e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
LKLMECAK_03698 1.2e-09 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKLMECAK_03699 8.4e-168 czcD P COG1230 Co Zn Cd efflux system component
LKLMECAK_03700 2.6e-194 trkA P Oxidoreductase
LKLMECAK_03703 1.8e-14 ykkA S Protein of unknown function (DUF664)
LKLMECAK_03704 3.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
LKLMECAK_03706 6.9e-195 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
LKLMECAK_03707 1.7e-50 ydeH
LKLMECAK_03708 2.6e-164 S Sodium Bile acid symporter family
LKLMECAK_03709 3.8e-201 adhA 1.1.1.1 C alcohol dehydrogenase
LKLMECAK_03710 3.6e-67 yraB K helix_turn_helix, mercury resistance
LKLMECAK_03711 4.3e-223 mleN_2 C antiporter
LKLMECAK_03712 8.3e-257 K helix_turn_helix gluconate operon transcriptional repressor
LKLMECAK_03713 3e-113 paiB K Transcriptional regulator
LKLMECAK_03715 1.1e-177 ydeR EGP Major facilitator Superfamily
LKLMECAK_03716 1.2e-100 ydeS K Transcriptional regulator
LKLMECAK_03717 1.9e-17 ydeS K Transcriptional regulator
LKLMECAK_03718 1.4e-47 yraD M Spore coat protein
LKLMECAK_03719 3.1e-24 yraE
LKLMECAK_03720 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LKLMECAK_03721 8.4e-63 yraF M Spore coat protein
LKLMECAK_03722 1.3e-35 yraG
LKLMECAK_03723 3.9e-216 ydfH 2.7.13.3 T Histidine kinase
LKLMECAK_03724 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKLMECAK_03725 0.0 ydfJ S drug exporters of the RND superfamily
LKLMECAK_03726 6.7e-133 puuD S Peptidase C26
LKLMECAK_03727 1.5e-297 expZ S ABC transporter
LKLMECAK_03728 2.3e-98 ynaD J Acetyltransferase (GNAT) domain
LKLMECAK_03729 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
LKLMECAK_03730 5e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
LKLMECAK_03731 3.9e-210 tcaB EGP Major facilitator Superfamily
LKLMECAK_03732 3.7e-224 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKLMECAK_03733 5e-156 K Helix-turn-helix XRE-family like proteins
LKLMECAK_03734 9.4e-122 ydhB S membrane transporter protein
LKLMECAK_03735 2.2e-81 bltD 2.3.1.57 K FR47-like protein
LKLMECAK_03736 7.6e-149 bltR K helix_turn_helix, mercury resistance
LKLMECAK_03737 1.2e-147 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LKLMECAK_03738 1.9e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
LKLMECAK_03739 2.4e-144 ycgJ_1 Q ubiE/COQ5 methyltransferase family
LKLMECAK_03740 2.1e-82 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
LKLMECAK_03743 1.6e-33 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
LKLMECAK_03744 2.4e-119 ydhC K FCD
LKLMECAK_03745 3.5e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LKLMECAK_03748 5.5e-261 pbpE V Beta-lactamase
LKLMECAK_03750 5.5e-98 ydhK M Protein of unknown function (DUF1541)
LKLMECAK_03751 2e-195 pbuE EGP Major facilitator Superfamily
LKLMECAK_03752 1.5e-132 ydhQ K UTRA
LKLMECAK_03753 9.9e-118 K FCD
LKLMECAK_03754 8.2e-216 yeaN P COG2807 Cyanate permease
LKLMECAK_03755 2.6e-49 sugE P Small Multidrug Resistance protein
LKLMECAK_03756 2.3e-51 ykkC P Small Multidrug Resistance protein
LKLMECAK_03757 2.9e-102 yvdT K Transcriptional regulator
LKLMECAK_03758 2.1e-296 yveA E amino acid
LKLMECAK_03759 1.9e-163 ydhU P Catalase
LKLMECAK_03760 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
LKLMECAK_03761 1.5e-183 yhfP 1.1.1.1 C Quinone oxidoreductase
LKLMECAK_03762 1.2e-250 iolT EGP Major facilitator Superfamily
LKLMECAK_03765 0.0 pksJ Q Polyketide synthase of type I
LKLMECAK_03766 0.0 1.1.1.320 Q Polyketide synthase of type I
LKLMECAK_03767 0.0 Q Polyketide synthase of type I
LKLMECAK_03768 1.5e-86 pksJ Q Polyketide synthase of type I
LKLMECAK_03769 7.7e-39 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_03770 2.2e-78 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKLMECAK_03771 2.6e-61 hxlR K transcriptional
LKLMECAK_03772 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
LKLMECAK_03773 1.6e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
LKLMECAK_03774 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
LKLMECAK_03775 1.5e-65 nin S Competence protein J (ComJ)
LKLMECAK_03776 9e-11 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LKLMECAK_03777 1.3e-48 S Protein of unknown function (DUF2680)
LKLMECAK_03778 3.1e-72 yckC S membrane
LKLMECAK_03779 2e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LKLMECAK_03780 6.6e-226 yciC S GTPases (G3E family)
LKLMECAK_03781 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LKLMECAK_03782 1.1e-55 nirD 1.7.1.15 P Nitrite reductase
LKLMECAK_03783 1.9e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LKLMECAK_03784 1.9e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LKLMECAK_03785 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
LKLMECAK_03786 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKLMECAK_03787 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LKLMECAK_03788 1.9e-169 ycgM E Proline dehydrogenase
LKLMECAK_03789 5.8e-146 ycgL S Predicted nucleotidyltransferase
LKLMECAK_03790 1.5e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
LKLMECAK_03791 4.3e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LKLMECAK_03792 4.8e-222 G COG0477 Permeases of the major facilitator superfamily
LKLMECAK_03793 2.5e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
LKLMECAK_03794 1.4e-107 tmrB S AAA domain
LKLMECAK_03796 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LKLMECAK_03797 7.6e-114 ycgI S Domain of unknown function (DUF1989)
LKLMECAK_03798 5.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
LKLMECAK_03799 7.6e-151 yqcI S YqcI/YcgG family
LKLMECAK_03800 3e-113 ycgF E Lysine exporter protein LysE YggA
LKLMECAK_03801 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
LKLMECAK_03802 8.1e-261 mdr EGP Major facilitator Superfamily
LKLMECAK_03803 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LKLMECAK_03804 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
LKLMECAK_03805 1.5e-80 ycgB
LKLMECAK_03806 2.5e-227 ycgA S Membrane
LKLMECAK_03807 2.4e-209 amhX S amidohydrolase
LKLMECAK_03808 1.5e-163 opuAC E glycine betaine
LKLMECAK_03809 1.6e-138 opuAB P glycine betaine
LKLMECAK_03810 3.9e-229 proV 3.6.3.32 E glycine betaine
LKLMECAK_03811 2e-214 naiP P Uncharacterised MFS-type transporter YbfB
LKLMECAK_03812 6.7e-193 yceH P Belongs to the TelA family
LKLMECAK_03813 0.0 yceG S Putative component of 'biosynthetic module'
LKLMECAK_03814 9.7e-138 terC P Protein of unknown function (DUF475)
LKLMECAK_03815 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
LKLMECAK_03816 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
LKLMECAK_03817 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
LKLMECAK_03818 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKLMECAK_03819 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LKLMECAK_03820 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LKLMECAK_03821 2.3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
LKLMECAK_03822 8.1e-168 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
LKLMECAK_03823 1.1e-149 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
LKLMECAK_03824 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
LKLMECAK_03825 1e-188 S response regulator aspartate phosphatase
LKLMECAK_03826 5.8e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
LKLMECAK_03827 1.3e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
LKLMECAK_03828 2.9e-257 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
LKLMECAK_03829 1.5e-175 ycdA S Domain of unknown function (DUF5105)
LKLMECAK_03830 6.2e-171 yccK C Aldo keto reductase
LKLMECAK_03831 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
LKLMECAK_03832 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LKLMECAK_03833 2.5e-195 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LKLMECAK_03834 6.5e-99 yxaF K Transcriptional regulator
LKLMECAK_03835 1e-241 lmrB EGP the major facilitator superfamily
LKLMECAK_03836 6e-205 ycbU E Selenocysteine lyase
LKLMECAK_03837 2.7e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LKLMECAK_03838 1.3e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LKLMECAK_03839 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LKLMECAK_03840 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
LKLMECAK_03841 5.3e-77 sleB 3.5.1.28 M Cell wall
LKLMECAK_03842 5.6e-62 ycbP S Protein of unknown function (DUF2512)
LKLMECAK_03843 2.4e-56 traF CO Thioredoxin
LKLMECAK_03844 4.4e-62 mhqP S DoxX
LKLMECAK_03845 4.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
LKLMECAK_03846 4.5e-109 ydfN C nitroreductase
LKLMECAK_03847 2.3e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKLMECAK_03848 1.2e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
LKLMECAK_03849 1.1e-124 ycbJ S Macrolide 2'-phosphotransferase
LKLMECAK_03850 2.2e-171 glnL T Regulator
LKLMECAK_03851 4.8e-206 phoQ 2.7.13.3 T Histidine kinase
LKLMECAK_03852 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
LKLMECAK_03853 2.7e-258 agcS E Sodium alanine symporter
LKLMECAK_03854 1.5e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
LKLMECAK_03855 1.5e-256 mmuP E amino acid
LKLMECAK_03856 9.5e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LKLMECAK_03857 9.3e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKLMECAK_03858 2.5e-191 yceA S Belongs to the UPF0176 family
LKLMECAK_03859 6.1e-42 ybfN
LKLMECAK_03860 7.3e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LKLMECAK_03861 1.9e-86 ybfM S SNARE associated Golgi protein
LKLMECAK_03862 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LKLMECAK_03863 1.2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LKLMECAK_03864 2.3e-193 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
LKLMECAK_03865 1.2e-82 K Helix-turn-helix XRE-family like proteins
LKLMECAK_03866 9.2e-32
LKLMECAK_03867 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
LKLMECAK_03869 2.1e-210 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
LKLMECAK_03870 1e-16 S Protein of unknown function (DUF2651)
LKLMECAK_03871 1.7e-259 glpT G -transporter
LKLMECAK_03872 3.7e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LKLMECAK_03873 5.5e-292 ybeC E amino acid
LKLMECAK_03874 9.2e-40 ybyB
LKLMECAK_03875 1.8e-106 yqeB
LKLMECAK_03876 7.5e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
LKLMECAK_03877 8.5e-76 S Domain of unknown function (DUF4879)
LKLMECAK_03878 5.1e-49 crtF 2.1.1.210 Q PFAM O-methyltransferase
LKLMECAK_03879 0.0 Q TIGRFAM amino acid adenylation domain
LKLMECAK_03880 1.2e-102 Q Flavin containing amine oxidoreductase
LKLMECAK_03881 0.0 Q Polyketide synthase modules and related proteins
LKLMECAK_03882 0.0 Q Beta-ketoacyl synthase
LKLMECAK_03883 8.7e-120 fabD 2.3.1.39 I PFAM Acyl transferase
LKLMECAK_03884 0.0 srfAC Q TIGRFAM amino acid adenylation domain
LKLMECAK_03885 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
LKLMECAK_03886 8.1e-59 bacT Q Thioesterase domain
LKLMECAK_03887 4.4e-14
LKLMECAK_03888 3.9e-122 V ABC-2 type transporter
LKLMECAK_03889 6.8e-146 V ABC-2 type transporter
LKLMECAK_03890 3.5e-134 V ABC transporter, ATP-binding protein
LKLMECAK_03891 3.8e-82 KT helix_turn_helix, Lux Regulon
LKLMECAK_03892 6.2e-104 T Histidine kinase
LKLMECAK_03893 1.5e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LKLMECAK_03894 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
LKLMECAK_03895 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
LKLMECAK_03896 6.9e-52 S LrgA family
LKLMECAK_03897 2.9e-93 yxaC M effector of murein hydrolase
LKLMECAK_03898 3.3e-163 dkgB S Aldo/keto reductase family
LKLMECAK_03899 3.7e-106 S ABC-2 family transporter protein
LKLMECAK_03900 7.6e-155 V ATPases associated with a variety of cellular activities
LKLMECAK_03901 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LKLMECAK_03902 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LKLMECAK_03903 1.3e-223 ybbR S protein conserved in bacteria
LKLMECAK_03904 1.8e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LKLMECAK_03905 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LKLMECAK_03906 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
LKLMECAK_03912 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
LKLMECAK_03913 7.7e-85 ybbJ J acetyltransferase
LKLMECAK_03914 2.9e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LKLMECAK_03915 1.6e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LKLMECAK_03916 5.8e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
LKLMECAK_03917 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
LKLMECAK_03918 1.2e-235 ybbC 3.2.1.52 S protein conserved in bacteria
LKLMECAK_03919 1.3e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
LKLMECAK_03920 3.4e-172 feuA P Iron-uptake system-binding protein
LKLMECAK_03921 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKLMECAK_03922 6.1e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKLMECAK_03923 1.9e-109 ybbA S Putative esterase
LKLMECAK_03924 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
LKLMECAK_03925 1.3e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
LKLMECAK_03926 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
LKLMECAK_03927 2.5e-175 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
LKLMECAK_03928 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKLMECAK_03929 1.6e-219 glcP G Major Facilitator Superfamily
LKLMECAK_03930 3.8e-30 csfB S Inhibitor of sigma-G Gin
LKLMECAK_03931 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LKLMECAK_03932 4.3e-187 yaaN P Belongs to the TelA family
LKLMECAK_03933 6.4e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
LKLMECAK_03934 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LKLMECAK_03935 7.5e-55 yaaQ S protein conserved in bacteria
LKLMECAK_03936 1.2e-71 yaaR S protein conserved in bacteria
LKLMECAK_03937 1.3e-182 holB 2.7.7.7 L DNA polymerase III
LKLMECAK_03938 8.8e-145 yaaT S stage 0 sporulation protein
LKLMECAK_03939 7.7e-37 yabA L Involved in initiation control of chromosome replication
LKLMECAK_03940 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
LKLMECAK_03941 5.2e-47 yazA L endonuclease containing a URI domain
LKLMECAK_03942 1.4e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LKLMECAK_03943 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
LKLMECAK_03944 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LKLMECAK_03945 4.5e-143 tatD L hydrolase, TatD
LKLMECAK_03946 2.7e-231 rpfB GH23 T protein conserved in bacteria
LKLMECAK_03947 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LKLMECAK_03948 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LKLMECAK_03949 8.4e-146 yabG S peptidase
LKLMECAK_03950 7.8e-39 veg S protein conserved in bacteria
LKLMECAK_03951 2.9e-27 sspF S DNA topological change
LKLMECAK_03952 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LKLMECAK_03953 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LKLMECAK_03954 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
LKLMECAK_03955 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LKLMECAK_03956 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LKLMECAK_03957 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LKLMECAK_03958 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LKLMECAK_03959 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LKLMECAK_03960 3.7e-40 yabK S Peptide ABC transporter permease
LKLMECAK_03961 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LKLMECAK_03962 6.2e-91 spoVT K stage V sporulation protein
LKLMECAK_03963 2.3e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKLMECAK_03964 8e-274 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LKLMECAK_03965 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LKLMECAK_03966 1.9e-49 yabP S Sporulation protein YabP
LKLMECAK_03967 2.9e-103 yabQ S spore cortex biosynthesis protein
LKLMECAK_03968 4.1e-57 divIC D Septum formation initiator
LKLMECAK_03969 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
LKLMECAK_03972 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
LKLMECAK_03973 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
LKLMECAK_03974 1.4e-184 KLT serine threonine protein kinase
LKLMECAK_03975 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LKLMECAK_03976 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LKLMECAK_03977 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LKLMECAK_03978 3.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LKLMECAK_03979 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LKLMECAK_03980 3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
LKLMECAK_03981 4.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LKLMECAK_03982 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LKLMECAK_03983 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
LKLMECAK_03984 4.2e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
LKLMECAK_03985 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LKLMECAK_03986 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LKLMECAK_03987 2.4e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LKLMECAK_03988 4.5e-29 yazB K transcriptional
LKLMECAK_03989 1.7e-187 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LKLMECAK_03990 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)