ORF_ID e_value Gene_name EC_number CAZy COGs Description
KCBGAEBN_00001 6.9e-30 yqkB S Belongs to the HesB IscA family
KCBGAEBN_00002 2.3e-65 yxkH G Polysaccharide deacetylase
KCBGAEBN_00003 9.6e-09
KCBGAEBN_00004 2.9e-53 K LysR substrate binding domain
KCBGAEBN_00005 2e-122 MA20_14895 S Conserved hypothetical protein 698
KCBGAEBN_00006 1.1e-199 nupG F Nucleoside
KCBGAEBN_00007 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCBGAEBN_00008 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KCBGAEBN_00009 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KCBGAEBN_00010 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KCBGAEBN_00011 3.9e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KCBGAEBN_00012 9e-20 yaaA S S4 domain protein YaaA
KCBGAEBN_00013 9.3e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCBGAEBN_00014 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCBGAEBN_00015 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCBGAEBN_00016 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
KCBGAEBN_00017 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KCBGAEBN_00018 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KCBGAEBN_00019 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
KCBGAEBN_00020 7.3e-117 S Glycosyl transferase family 2
KCBGAEBN_00021 7.4e-64 D peptidase
KCBGAEBN_00022 0.0 asnB 6.3.5.4 E Asparagine synthase
KCBGAEBN_00023 1.9e-47 yiiE S Protein of unknown function (DUF1211)
KCBGAEBN_00024 7.8e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KCBGAEBN_00025 6.3e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KCBGAEBN_00026 3.6e-17 yneR
KCBGAEBN_00027 8.7e-231 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KCBGAEBN_00028 4.9e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
KCBGAEBN_00029 2.4e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KCBGAEBN_00030 9.9e-153 mdtG EGP Major facilitator Superfamily
KCBGAEBN_00031 1e-14 yobS K transcriptional regulator
KCBGAEBN_00032 2.8e-109 glcU U sugar transport
KCBGAEBN_00033 3.4e-170 yjjP S Putative threonine/serine exporter
KCBGAEBN_00034 1.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
KCBGAEBN_00035 3.7e-96 yicL EG EamA-like transporter family
KCBGAEBN_00036 6e-223 pepF E Oligopeptidase F
KCBGAEBN_00037 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KCBGAEBN_00038 4.9e-178 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KCBGAEBN_00039 6.6e-140 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
KCBGAEBN_00040 4.1e-61 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KCBGAEBN_00041 4e-23 relB L RelB antitoxin
KCBGAEBN_00043 2.9e-172 S Putative peptidoglycan binding domain
KCBGAEBN_00044 1.2e-31 K Transcriptional regulator, MarR family
KCBGAEBN_00045 1.4e-216 XK27_09600 V ABC transporter, ATP-binding protein
KCBGAEBN_00046 1.1e-229 V ABC transporter transmembrane region
KCBGAEBN_00047 1.7e-06
KCBGAEBN_00048 9.1e-93 S Domain of unknown function DUF87
KCBGAEBN_00050 7.9e-106 yxeH S hydrolase
KCBGAEBN_00051 9e-114 K response regulator
KCBGAEBN_00052 1.1e-272 vicK 2.7.13.3 T Histidine kinase
KCBGAEBN_00053 4.6e-103 yycH S YycH protein
KCBGAEBN_00054 5.6e-80 yycI S YycH protein
KCBGAEBN_00055 3.1e-30 yyaQ S YjbR
KCBGAEBN_00056 2.7e-114 vicX 3.1.26.11 S domain protein
KCBGAEBN_00057 3.7e-145 htrA 3.4.21.107 O serine protease
KCBGAEBN_00058 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCBGAEBN_00059 4.4e-40 1.6.5.2 GM NAD(P)H-binding
KCBGAEBN_00060 3.3e-25 K MarR family transcriptional regulator
KCBGAEBN_00061 5.9e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
KCBGAEBN_00062 2e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KCBGAEBN_00064 9.4e-208 G glycerol-3-phosphate transporter
KCBGAEBN_00065 5.9e-30 L Helix-turn-helix domain
KCBGAEBN_00066 1e-20 L HTH-like domain
KCBGAEBN_00067 8e-37 L Integrase core domain
KCBGAEBN_00068 3.5e-26 L PFAM transposase IS200-family protein
KCBGAEBN_00072 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KCBGAEBN_00073 1.2e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KCBGAEBN_00074 1.1e-68 coiA 3.6.4.12 S Competence protein
KCBGAEBN_00075 1.9e-232 pepF E oligoendopeptidase F
KCBGAEBN_00076 1e-41 yjbH Q Thioredoxin
KCBGAEBN_00077 6.4e-98 pstS P Phosphate
KCBGAEBN_00078 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
KCBGAEBN_00079 5.1e-122 pstA P Phosphate transport system permease protein PstA
KCBGAEBN_00080 4.5e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCBGAEBN_00081 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCBGAEBN_00082 2.7e-56 P Plays a role in the regulation of phosphate uptake
KCBGAEBN_00083 6.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KCBGAEBN_00084 9.2e-79 S VIT family
KCBGAEBN_00085 1.8e-82 S membrane
KCBGAEBN_00086 2.5e-41 M1-874 K Domain of unknown function (DUF1836)
KCBGAEBN_00087 2.3e-65 hly S protein, hemolysin III
KCBGAEBN_00088 2.1e-34 K helix_turn_helix, Arsenical Resistance Operon Repressor
KCBGAEBN_00089 1.7e-74 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCBGAEBN_00092 1.5e-13
KCBGAEBN_00093 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KCBGAEBN_00094 1.3e-158 ccpA K catabolite control protein A
KCBGAEBN_00095 3.7e-42 S VanZ like family
KCBGAEBN_00096 1.5e-119 yebC K Transcriptional regulatory protein
KCBGAEBN_00097 2.3e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KCBGAEBN_00098 4.7e-121 comGA NU Type II IV secretion system protein
KCBGAEBN_00099 5.7e-98 comGB NU type II secretion system
KCBGAEBN_00100 1.2e-27 comGC U competence protein ComGC
KCBGAEBN_00101 1.5e-13
KCBGAEBN_00103 5.5e-11 S Putative Competence protein ComGF
KCBGAEBN_00105 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
KCBGAEBN_00106 1.6e-183 cycA E Amino acid permease
KCBGAEBN_00107 3e-57 S Calcineurin-like phosphoesterase
KCBGAEBN_00108 1.9e-53 yutD S Protein of unknown function (DUF1027)
KCBGAEBN_00109 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KCBGAEBN_00110 7.8e-32 S Protein of unknown function (DUF1461)
KCBGAEBN_00111 5.1e-92 dedA S SNARE associated Golgi protein
KCBGAEBN_00112 5.5e-96 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KCBGAEBN_00113 8.8e-50 yugI 5.3.1.9 J general stress protein
KCBGAEBN_00119 2.1e-07
KCBGAEBN_00122 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCBGAEBN_00123 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCBGAEBN_00124 2.4e-192 cycA E Amino acid permease
KCBGAEBN_00125 2.4e-186 ytgP S Polysaccharide biosynthesis protein
KCBGAEBN_00126 2.8e-62 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCBGAEBN_00127 1.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KCBGAEBN_00128 8.7e-193 pepV 3.5.1.18 E dipeptidase PepV
KCBGAEBN_00129 6.3e-63 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KCBGAEBN_00130 5.6e-67 L Type III restriction enzyme, res subunit
KCBGAEBN_00131 0.0 L Type III restriction enzyme, res subunit
KCBGAEBN_00133 4e-36
KCBGAEBN_00134 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KCBGAEBN_00135 4.2e-61 marR K Transcriptional regulator, MarR family
KCBGAEBN_00136 7.1e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCBGAEBN_00137 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCBGAEBN_00138 6.5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KCBGAEBN_00139 6.5e-99 IQ reductase
KCBGAEBN_00140 1.8e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KCBGAEBN_00141 7.9e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KCBGAEBN_00142 1.5e-63 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KCBGAEBN_00143 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KCBGAEBN_00144 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCBGAEBN_00145 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KCBGAEBN_00146 4.6e-108 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KCBGAEBN_00147 2.8e-229 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KCBGAEBN_00148 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
KCBGAEBN_00149 4.6e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KCBGAEBN_00150 5.7e-119 gla U Major intrinsic protein
KCBGAEBN_00151 5.8e-45 ykuL S CBS domain
KCBGAEBN_00152 1.5e-60 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KCBGAEBN_00153 7.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KCBGAEBN_00154 1.5e-86 ykuT M mechanosensitive ion channel
KCBGAEBN_00156 5e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCBGAEBN_00157 2e-21 yheA S Belongs to the UPF0342 family
KCBGAEBN_00158 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
KCBGAEBN_00159 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KCBGAEBN_00161 5.4e-53 hit FG histidine triad
KCBGAEBN_00162 1.3e-94 ecsA V ABC transporter, ATP-binding protein
KCBGAEBN_00163 1.4e-71 ecsB U ABC transporter
KCBGAEBN_00164 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
KCBGAEBN_00165 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KCBGAEBN_00166 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KCBGAEBN_00167 2.3e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCBGAEBN_00168 3.8e-238 sftA D Belongs to the FtsK SpoIIIE SftA family
KCBGAEBN_00169 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KCBGAEBN_00170 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
KCBGAEBN_00171 6.7e-69 ybhL S Belongs to the BI1 family
KCBGAEBN_00172 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCBGAEBN_00173 3.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KCBGAEBN_00174 2.1e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KCBGAEBN_00175 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCBGAEBN_00176 1.6e-79 dnaB L replication initiation and membrane attachment
KCBGAEBN_00177 2.2e-107 dnaI L Primosomal protein DnaI
KCBGAEBN_00178 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCBGAEBN_00179 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCBGAEBN_00180 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KCBGAEBN_00181 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCBGAEBN_00182 2.5e-71 yqeG S HAD phosphatase, family IIIA
KCBGAEBN_00183 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
KCBGAEBN_00184 1e-29 yhbY J RNA-binding protein
KCBGAEBN_00185 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCBGAEBN_00186 7.2e-72 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KCBGAEBN_00187 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KCBGAEBN_00188 5.5e-82 H Nodulation protein S (NodS)
KCBGAEBN_00189 1.3e-122 ylbM S Belongs to the UPF0348 family
KCBGAEBN_00190 3.9e-56 yceD S Uncharacterized ACR, COG1399
KCBGAEBN_00191 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KCBGAEBN_00192 1.2e-88 plsC 2.3.1.51 I Acyltransferase
KCBGAEBN_00193 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
KCBGAEBN_00194 1.5e-27 yazA L GIY-YIG catalytic domain protein
KCBGAEBN_00195 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
KCBGAEBN_00196 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCBGAEBN_00197 6.9e-37
KCBGAEBN_00198 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KCBGAEBN_00199 1.8e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KCBGAEBN_00200 2.7e-157 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KCBGAEBN_00201 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCBGAEBN_00202 9.5e-106 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KCBGAEBN_00204 3.1e-111 K response regulator
KCBGAEBN_00205 5e-167 arlS 2.7.13.3 T Histidine kinase
KCBGAEBN_00206 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCBGAEBN_00207 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KCBGAEBN_00208 1.6e-136 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KCBGAEBN_00209 7.3e-105
KCBGAEBN_00210 7.2e-117
KCBGAEBN_00211 1.3e-41 dut S dUTPase
KCBGAEBN_00212 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCBGAEBN_00213 3.7e-46 yqhY S Asp23 family, cell envelope-related function
KCBGAEBN_00214 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCBGAEBN_00215 3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCBGAEBN_00216 2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KCBGAEBN_00217 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KCBGAEBN_00218 1.4e-82 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KCBGAEBN_00219 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KCBGAEBN_00220 1.5e-48 argR K Regulates arginine biosynthesis genes
KCBGAEBN_00221 2.7e-177 recN L May be involved in recombinational repair of damaged DNA
KCBGAEBN_00222 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KCBGAEBN_00223 2.2e-30 ynzC S UPF0291 protein
KCBGAEBN_00224 5.9e-27 yneF S UPF0154 protein
KCBGAEBN_00225 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
KCBGAEBN_00226 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
KCBGAEBN_00227 2.1e-74 yciQ P membrane protein (DUF2207)
KCBGAEBN_00228 3e-19 D nuclear chromosome segregation
KCBGAEBN_00229 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KCBGAEBN_00230 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCBGAEBN_00231 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
KCBGAEBN_00232 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
KCBGAEBN_00233 4.7e-158 glk 2.7.1.2 G Glucokinase
KCBGAEBN_00234 8e-46 yqhL P Rhodanese-like protein
KCBGAEBN_00235 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
KCBGAEBN_00236 1.9e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCBGAEBN_00237 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
KCBGAEBN_00238 1.3e-45 glnR K Transcriptional regulator
KCBGAEBN_00239 2e-247 glnA 6.3.1.2 E glutamine synthetase
KCBGAEBN_00241 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KCBGAEBN_00242 2.7e-48 S Domain of unknown function (DUF956)
KCBGAEBN_00243 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KCBGAEBN_00244 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KCBGAEBN_00245 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCBGAEBN_00246 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
KCBGAEBN_00247 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KCBGAEBN_00248 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KCBGAEBN_00249 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCBGAEBN_00250 8e-66 rimP J Required for maturation of 30S ribosomal subunits
KCBGAEBN_00251 4.8e-170 nusA K Participates in both transcription termination and antitermination
KCBGAEBN_00252 1.4e-39 ylxR K Protein of unknown function (DUF448)
KCBGAEBN_00253 6.8e-26 ylxQ J ribosomal protein
KCBGAEBN_00254 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KCBGAEBN_00255 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KCBGAEBN_00256 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KCBGAEBN_00257 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KCBGAEBN_00258 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KCBGAEBN_00259 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCBGAEBN_00260 1.5e-274 dnaK O Heat shock 70 kDa protein
KCBGAEBN_00261 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KCBGAEBN_00262 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KCBGAEBN_00264 9.2e-206 glnP P ABC transporter
KCBGAEBN_00265 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KCBGAEBN_00266 1.5e-31
KCBGAEBN_00267 2e-111 ampC V Beta-lactamase
KCBGAEBN_00268 3.5e-110 cobQ S glutamine amidotransferase
KCBGAEBN_00269 4.7e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
KCBGAEBN_00270 6.8e-86 tdk 2.7.1.21 F thymidine kinase
KCBGAEBN_00271 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCBGAEBN_00272 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KCBGAEBN_00273 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KCBGAEBN_00274 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCBGAEBN_00275 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
KCBGAEBN_00276 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCBGAEBN_00277 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KCBGAEBN_00278 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCBGAEBN_00279 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCBGAEBN_00280 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KCBGAEBN_00281 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KCBGAEBN_00282 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KCBGAEBN_00283 4.1e-15 ywzB S Protein of unknown function (DUF1146)
KCBGAEBN_00284 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCBGAEBN_00285 6e-141 mbl D Cell shape determining protein MreB Mrl
KCBGAEBN_00286 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KCBGAEBN_00287 1.8e-12 S Protein of unknown function (DUF2969)
KCBGAEBN_00288 6.1e-187 rodA D Belongs to the SEDS family
KCBGAEBN_00289 7.9e-26 arsC 1.20.4.1 P Belongs to the ArsC family
KCBGAEBN_00290 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
KCBGAEBN_00291 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KCBGAEBN_00292 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KCBGAEBN_00293 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCBGAEBN_00294 2.4e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCBGAEBN_00295 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCBGAEBN_00296 6.4e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCBGAEBN_00297 3.3e-90 stp 3.1.3.16 T phosphatase
KCBGAEBN_00298 3.4e-191 KLT serine threonine protein kinase
KCBGAEBN_00299 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KCBGAEBN_00300 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
KCBGAEBN_00301 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KCBGAEBN_00302 4.5e-53 asp S Asp23 family, cell envelope-related function
KCBGAEBN_00303 3.7e-238 yloV S DAK2 domain fusion protein YloV
KCBGAEBN_00304 3.3e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCBGAEBN_00305 2.1e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KCBGAEBN_00306 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCBGAEBN_00307 2.5e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KCBGAEBN_00308 4.7e-211 smc D Required for chromosome condensation and partitioning
KCBGAEBN_00309 9.1e-149 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KCBGAEBN_00310 7e-40 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KCBGAEBN_00311 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCBGAEBN_00312 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KCBGAEBN_00313 1.1e-26 ylqC S Belongs to the UPF0109 family
KCBGAEBN_00314 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCBGAEBN_00315 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KCBGAEBN_00316 5.7e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
KCBGAEBN_00317 3.5e-197 yfnA E amino acid
KCBGAEBN_00318 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KCBGAEBN_00319 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
KCBGAEBN_00320 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KCBGAEBN_00321 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCBGAEBN_00322 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCBGAEBN_00323 4e-18 S Tetratricopeptide repeat
KCBGAEBN_00324 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCBGAEBN_00325 1.7e-195 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KCBGAEBN_00326 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCBGAEBN_00327 2.3e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KCBGAEBN_00328 1.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCBGAEBN_00329 5e-23 ykzG S Belongs to the UPF0356 family
KCBGAEBN_00330 1.6e-24
KCBGAEBN_00331 8.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KCBGAEBN_00332 3.7e-32 1.1.1.27 C L-malate dehydrogenase activity
KCBGAEBN_00333 1.7e-23 yktA S Belongs to the UPF0223 family
KCBGAEBN_00334 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KCBGAEBN_00335 0.0 typA T GTP-binding protein TypA
KCBGAEBN_00336 6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KCBGAEBN_00337 1.6e-114 manY G PTS system
KCBGAEBN_00338 3.3e-148 manN G system, mannose fructose sorbose family IID component
KCBGAEBN_00339 1.6e-102 ftsW D Belongs to the SEDS family
KCBGAEBN_00340 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KCBGAEBN_00341 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KCBGAEBN_00342 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KCBGAEBN_00343 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCBGAEBN_00344 2.4e-131 ylbL T Belongs to the peptidase S16 family
KCBGAEBN_00345 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KCBGAEBN_00346 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCBGAEBN_00347 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCBGAEBN_00348 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCBGAEBN_00349 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KCBGAEBN_00350 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KCBGAEBN_00351 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCBGAEBN_00352 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KCBGAEBN_00353 1e-152 purD 6.3.4.13 F Belongs to the GARS family
KCBGAEBN_00354 1.5e-93 S Acyltransferase family
KCBGAEBN_00355 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCBGAEBN_00356 3.9e-122 K LysR substrate binding domain
KCBGAEBN_00358 2.2e-20
KCBGAEBN_00359 6.2e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KCBGAEBN_00360 2.2e-267 argS 6.1.1.19 J Arginyl-tRNA synthetase
KCBGAEBN_00361 1.4e-50 comEA L Competence protein ComEA
KCBGAEBN_00362 2e-69 comEB 3.5.4.12 F ComE operon protein 2
KCBGAEBN_00363 3.3e-154 comEC S Competence protein ComEC
KCBGAEBN_00364 9.3e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
KCBGAEBN_00365 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KCBGAEBN_00366 3e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KCBGAEBN_00367 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KCBGAEBN_00368 1.8e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KCBGAEBN_00369 3.9e-229 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KCBGAEBN_00370 1.8e-36 ypmB S Protein conserved in bacteria
KCBGAEBN_00371 1.2e-142 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KCBGAEBN_00372 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KCBGAEBN_00373 5.1e-56 dnaD L DnaD domain protein
KCBGAEBN_00374 4.4e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCBGAEBN_00375 5.8e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCBGAEBN_00376 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCBGAEBN_00377 1.9e-93 M transferase activity, transferring glycosyl groups
KCBGAEBN_00378 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
KCBGAEBN_00379 5.8e-100 epsJ1 M Glycosyltransferase like family 2
KCBGAEBN_00382 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KCBGAEBN_00383 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KCBGAEBN_00384 1.8e-56 yqeY S YqeY-like protein
KCBGAEBN_00386 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
KCBGAEBN_00387 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCBGAEBN_00388 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KCBGAEBN_00389 6.6e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KCBGAEBN_00390 2.9e-276 yfmR S ABC transporter, ATP-binding protein
KCBGAEBN_00391 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KCBGAEBN_00392 3.2e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCBGAEBN_00393 8.6e-135 yvgN C Aldo keto reductase
KCBGAEBN_00394 2.4e-35 K helix_turn_helix, mercury resistance
KCBGAEBN_00395 1.3e-102 S Aldo keto reductase
KCBGAEBN_00397 6.5e-80 ypmR E GDSL-like Lipase/Acylhydrolase
KCBGAEBN_00398 2.2e-52 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
KCBGAEBN_00399 3.6e-24 yozE S Belongs to the UPF0346 family
KCBGAEBN_00400 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCBGAEBN_00401 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCBGAEBN_00402 6.2e-85 dprA LU DNA protecting protein DprA
KCBGAEBN_00403 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCBGAEBN_00404 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KCBGAEBN_00405 5.8e-205 G PTS system Galactitol-specific IIC component
KCBGAEBN_00406 2.3e-81 K Bacterial regulatory proteins, tetR family
KCBGAEBN_00407 1.6e-128 yjjC V ATPases associated with a variety of cellular activities
KCBGAEBN_00408 2.1e-203 M Exporter of polyketide antibiotics
KCBGAEBN_00409 1.8e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KCBGAEBN_00410 2.7e-35 S Repeat protein
KCBGAEBN_00411 2e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KCBGAEBN_00412 3.4e-91 L Belongs to the 'phage' integrase family
KCBGAEBN_00413 4.3e-14 L Belongs to the 'phage' integrase family
KCBGAEBN_00415 1.4e-22 dinG 2.7.7.7, 3.6.4.12 L DNA-directed DNA polymerase activity
KCBGAEBN_00416 1.9e-13
KCBGAEBN_00417 1.7e-17 L nuclease
KCBGAEBN_00418 9.6e-28 S Short C-terminal domain
KCBGAEBN_00420 8.4e-38 E Zn peptidase
KCBGAEBN_00421 2.4e-37 K Helix-turn-helix XRE-family like proteins
KCBGAEBN_00422 3.5e-10 XK27_07105 K Helix-turn-helix XRE-family like proteins
KCBGAEBN_00425 3.8e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCBGAEBN_00426 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KCBGAEBN_00427 9.1e-43 yodB K Transcriptional regulator, HxlR family
KCBGAEBN_00428 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCBGAEBN_00429 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCBGAEBN_00430 1.5e-126 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCBGAEBN_00431 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
KCBGAEBN_00432 2.2e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KCBGAEBN_00433 6.4e-12
KCBGAEBN_00434 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
KCBGAEBN_00435 1.3e-42 XK27_03960 S Protein of unknown function (DUF3013)
KCBGAEBN_00436 1.9e-116 prmA J Ribosomal protein L11 methyltransferase
KCBGAEBN_00437 1.8e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KCBGAEBN_00438 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCBGAEBN_00439 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KCBGAEBN_00440 2.5e-56 3.1.3.18 J HAD-hyrolase-like
KCBGAEBN_00441 5.2e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KCBGAEBN_00442 5.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCBGAEBN_00443 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KCBGAEBN_00444 2.7e-204 pyrP F Permease
KCBGAEBN_00445 2.8e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KCBGAEBN_00446 2.2e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KCBGAEBN_00447 2e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KCBGAEBN_00448 2.3e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCBGAEBN_00449 8.3e-134 K Transcriptional regulator
KCBGAEBN_00450 1.1e-143 ppaC 3.6.1.1 C inorganic pyrophosphatase
KCBGAEBN_00451 8.6e-115 glcR K DeoR C terminal sensor domain
KCBGAEBN_00452 4.5e-171 patA 2.6.1.1 E Aminotransferase
KCBGAEBN_00453 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KCBGAEBN_00455 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KCBGAEBN_00456 6.1e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KCBGAEBN_00457 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
KCBGAEBN_00458 6.2e-21 S Family of unknown function (DUF5322)
KCBGAEBN_00459 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KCBGAEBN_00460 8e-39
KCBGAEBN_00464 2.8e-16 V PFAM secretion protein HlyD family protein
KCBGAEBN_00466 8.7e-150 EGP Sugar (and other) transporter
KCBGAEBN_00467 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
KCBGAEBN_00468 5.7e-104 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KCBGAEBN_00469 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KCBGAEBN_00470 4.2e-73 alkD L DNA alkylation repair enzyme
KCBGAEBN_00471 3.8e-136 EG EamA-like transporter family
KCBGAEBN_00472 3.6e-150 S Tetratricopeptide repeat protein
KCBGAEBN_00473 2.4e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
KCBGAEBN_00474 8.7e-299 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KCBGAEBN_00475 7e-127 corA P CorA-like Mg2+ transporter protein
KCBGAEBN_00476 8.5e-161 nhaC C Na H antiporter NhaC
KCBGAEBN_00477 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KCBGAEBN_00478 2.2e-80 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KCBGAEBN_00480 4.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCBGAEBN_00481 5.8e-155 iscS 2.8.1.7 E Aminotransferase class V
KCBGAEBN_00482 3.7e-41 XK27_04120 S Putative amino acid metabolism
KCBGAEBN_00483 3.7e-202 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KCBGAEBN_00484 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KCBGAEBN_00485 4.3e-15 S Protein of unknown function (DUF2929)
KCBGAEBN_00486 0.0 dnaE 2.7.7.7 L DNA polymerase
KCBGAEBN_00487 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KCBGAEBN_00488 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KCBGAEBN_00490 2.2e-39 ypaA S Protein of unknown function (DUF1304)
KCBGAEBN_00491 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KCBGAEBN_00492 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCBGAEBN_00493 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCBGAEBN_00494 1.6e-201 FbpA K Fibronectin-binding protein
KCBGAEBN_00495 3.1e-40 K Transcriptional regulator
KCBGAEBN_00496 3.4e-99 degV S EDD domain protein, DegV family
KCBGAEBN_00497 2.4e-40 6.3.3.2 S ASCH
KCBGAEBN_00498 1.8e-175 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCBGAEBN_00499 5.3e-81 yjjH S Calcineurin-like phosphoesterase
KCBGAEBN_00500 1.8e-95 EG EamA-like transporter family
KCBGAEBN_00501 2.5e-84 natB CP ABC-type Na efflux pump, permease component
KCBGAEBN_00502 4e-111 natA S Domain of unknown function (DUF4162)
KCBGAEBN_00503 6.2e-23 K Acetyltransferase (GNAT) domain
KCBGAEBN_00505 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KCBGAEBN_00506 2.2e-227 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KCBGAEBN_00507 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
KCBGAEBN_00508 1.3e-59 arsC 1.20.4.1 T Low molecular weight phosphatase family
KCBGAEBN_00509 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KCBGAEBN_00510 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCBGAEBN_00511 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
KCBGAEBN_00512 1.2e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCBGAEBN_00513 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
KCBGAEBN_00514 2e-90 recO L Involved in DNA repair and RecF pathway recombination
KCBGAEBN_00515 4.6e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCBGAEBN_00516 2.8e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KCBGAEBN_00517 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KCBGAEBN_00518 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
KCBGAEBN_00519 2.6e-83 lytH 3.5.1.28 M Ami_3
KCBGAEBN_00520 2.6e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KCBGAEBN_00521 7.7e-12 M Lysin motif
KCBGAEBN_00522 2.2e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KCBGAEBN_00523 1.4e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
KCBGAEBN_00524 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
KCBGAEBN_00525 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
KCBGAEBN_00526 3.2e-120 ica2 GT2 M Glycosyl transferase family group 2
KCBGAEBN_00527 1.4e-43
KCBGAEBN_00528 7.2e-92 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KCBGAEBN_00530 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KCBGAEBN_00531 3.4e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KCBGAEBN_00532 2.8e-280 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KCBGAEBN_00533 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KCBGAEBN_00534 3.7e-109 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
KCBGAEBN_00535 3.1e-75 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KCBGAEBN_00536 6.3e-65 hsdS-1 3.1.21.3 V Type I restriction modification DNA specificity domain
KCBGAEBN_00537 4.7e-131 L Belongs to the 'phage' integrase family
KCBGAEBN_00538 8.9e-81 3.1.21.3 V type I restriction modification DNA specificity domain protein
KCBGAEBN_00539 1.3e-67 3.1.21.3 V Type I restriction modification DNA specificity domain
KCBGAEBN_00540 4e-202 hsdM 2.1.1.72 V type I restriction-modification system
KCBGAEBN_00541 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KCBGAEBN_00543 5.2e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
KCBGAEBN_00544 5.7e-57 3.6.1.27 I Acid phosphatase homologues
KCBGAEBN_00545 1.8e-68 maa 2.3.1.79 S Maltose acetyltransferase
KCBGAEBN_00546 4.8e-73 2.3.1.178 M GNAT acetyltransferase
KCBGAEBN_00548 1.4e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
KCBGAEBN_00549 3.5e-65 ypsA S Belongs to the UPF0398 family
KCBGAEBN_00550 6.4e-09 nhaC C Na H antiporter NhaC
KCBGAEBN_00551 2.9e-168 nhaC C Na H antiporter NhaC
KCBGAEBN_00552 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KCBGAEBN_00553 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KCBGAEBN_00554 4.3e-113 xerD D recombinase XerD
KCBGAEBN_00555 2.4e-124 cvfB S S1 domain
KCBGAEBN_00556 4.1e-51 yeaL S Protein of unknown function (DUF441)
KCBGAEBN_00557 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KCBGAEBN_00558 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCBGAEBN_00559 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCBGAEBN_00560 7e-59 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCBGAEBN_00561 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCBGAEBN_00562 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KCBGAEBN_00563 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KCBGAEBN_00564 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
KCBGAEBN_00565 4.5e-179 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KCBGAEBN_00566 1.3e-99 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KCBGAEBN_00568 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KCBGAEBN_00569 1e-27 ysxB J Cysteine protease Prp
KCBGAEBN_00570 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
KCBGAEBN_00573 2.9e-08 S Protein of unknown function (DUF2922)
KCBGAEBN_00575 1.3e-16 K DNA-templated transcription, initiation
KCBGAEBN_00577 1.1e-64 H Methyltransferase domain
KCBGAEBN_00578 1.7e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
KCBGAEBN_00579 1.3e-40 wecD M Acetyltransferase (GNAT) family
KCBGAEBN_00581 3.6e-26 ybl78 L Conserved phage C-terminus (Phg_2220_C)
KCBGAEBN_00582 1.3e-40 S Protein of unknown function (DUF1211)
KCBGAEBN_00583 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
KCBGAEBN_00584 2.7e-30 S CHY zinc finger
KCBGAEBN_00585 2.1e-39 K Transcriptional regulator
KCBGAEBN_00586 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
KCBGAEBN_00587 6.3e-09
KCBGAEBN_00589 5.6e-126 M Glycosyl transferases group 1
KCBGAEBN_00590 3.4e-64 M Glycosyl transferases group 1
KCBGAEBN_00591 3.5e-166 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KCBGAEBN_00592 8e-146 lspL 5.1.3.6 GM RmlD substrate binding domain
KCBGAEBN_00593 1.4e-103 cps2I S Psort location CytoplasmicMembrane, score
KCBGAEBN_00594 2.3e-60 cps1B GT2,GT4 M Glycosyl transferases group 1
KCBGAEBN_00595 8e-117 S Glycosyltransferase WbsX
KCBGAEBN_00596 5.4e-53
KCBGAEBN_00598 9.7e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
KCBGAEBN_00599 3.3e-41 GT2 S Glycosyltransferase, group 2 family protein
KCBGAEBN_00600 2.9e-74 M Glycosyltransferase Family 4
KCBGAEBN_00601 3.2e-76 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
KCBGAEBN_00602 3.6e-80 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
KCBGAEBN_00603 1.2e-120 2.4.1.52 GT4 M Glycosyl transferases group 1
KCBGAEBN_00604 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
KCBGAEBN_00605 1.6e-77 epsL M Bacterial sugar transferase
KCBGAEBN_00606 2.8e-168 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
KCBGAEBN_00607 9.1e-222 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M Psort location CytoplasmicMembrane, score
KCBGAEBN_00608 5.3e-48 cps4C M Chain length determinant protein
KCBGAEBN_00609 3e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KCBGAEBN_00610 1.3e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KCBGAEBN_00611 8.1e-81
KCBGAEBN_00612 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KCBGAEBN_00613 1e-113 yitU 3.1.3.104 S hydrolase
KCBGAEBN_00614 6.2e-59 speG J Acetyltransferase (GNAT) domain
KCBGAEBN_00615 2.6e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KCBGAEBN_00616 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KCBGAEBN_00617 5e-204 pipD E Dipeptidase
KCBGAEBN_00618 1.9e-44
KCBGAEBN_00619 1.6e-64 K helix_turn_helix, arabinose operon control protein
KCBGAEBN_00620 9.9e-53 S Membrane
KCBGAEBN_00621 0.0 rafA 3.2.1.22 G alpha-galactosidase
KCBGAEBN_00622 2.3e-59 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
KCBGAEBN_00623 2.2e-307 L Helicase C-terminal domain protein
KCBGAEBN_00624 1.1e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
KCBGAEBN_00625 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
KCBGAEBN_00626 1.4e-113 2.7.7.65 T diguanylate cyclase activity
KCBGAEBN_00627 9.4e-222 ydaN S Bacterial cellulose synthase subunit
KCBGAEBN_00628 3.9e-75 ydaN S Bacterial cellulose synthase subunit
KCBGAEBN_00629 1.5e-201 ydaM M Glycosyl transferase family group 2
KCBGAEBN_00630 6.5e-205 S Protein conserved in bacteria
KCBGAEBN_00631 7.9e-181
KCBGAEBN_00632 3.6e-127 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
KCBGAEBN_00633 4.9e-32 2.7.7.65 T GGDEF domain
KCBGAEBN_00635 1.5e-146 pbuO_1 S Permease family
KCBGAEBN_00636 1.9e-156 ndh 1.6.99.3 C NADH dehydrogenase
KCBGAEBN_00637 2e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KCBGAEBN_00638 2.4e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KCBGAEBN_00639 2.3e-219 cydD CO ABC transporter transmembrane region
KCBGAEBN_00640 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KCBGAEBN_00641 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KCBGAEBN_00642 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
KCBGAEBN_00643 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
KCBGAEBN_00644 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
KCBGAEBN_00645 5e-19 glpE P Rhodanese Homology Domain
KCBGAEBN_00646 4.2e-49 lytE M LysM domain protein
KCBGAEBN_00647 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
KCBGAEBN_00648 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
KCBGAEBN_00650 4.4e-74 draG O ADP-ribosylglycohydrolase
KCBGAEBN_00651 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KCBGAEBN_00652 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KCBGAEBN_00653 1.1e-61 divIVA D DivIVA domain protein
KCBGAEBN_00654 1.7e-81 ylmH S S4 domain protein
KCBGAEBN_00655 3e-19 yggT S YGGT family
KCBGAEBN_00656 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KCBGAEBN_00657 9.8e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCBGAEBN_00658 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KCBGAEBN_00659 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KCBGAEBN_00660 1.2e-152 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCBGAEBN_00661 3.2e-184 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KCBGAEBN_00662 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCBGAEBN_00663 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
KCBGAEBN_00664 2.5e-11 ftsL D cell division protein FtsL
KCBGAEBN_00665 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KCBGAEBN_00666 1.5e-55 mraZ K Belongs to the MraZ family
KCBGAEBN_00667 2.2e-07 S Protein of unknown function (DUF3397)
KCBGAEBN_00668 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
KCBGAEBN_00670 9.8e-100 D Alpha beta
KCBGAEBN_00671 3.7e-109 aatB ET ABC transporter substrate-binding protein
KCBGAEBN_00672 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KCBGAEBN_00673 1.9e-94 glnP P ABC transporter permease
KCBGAEBN_00674 1.8e-126 minD D Belongs to the ParA family
KCBGAEBN_00675 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KCBGAEBN_00676 1.5e-54 mreD M rod shape-determining protein MreD
KCBGAEBN_00677 2.1e-88 mreC M Involved in formation and maintenance of cell shape
KCBGAEBN_00678 3.6e-156 mreB D cell shape determining protein MreB
KCBGAEBN_00679 4.5e-21 K Cold shock
KCBGAEBN_00680 3.1e-79 radC L DNA repair protein
KCBGAEBN_00681 1.1e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KCBGAEBN_00682 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KCBGAEBN_00683 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCBGAEBN_00684 6.4e-162 iscS2 2.8.1.7 E Aminotransferase class V
KCBGAEBN_00685 1.3e-174 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KCBGAEBN_00686 7.1e-56 ytsP 1.8.4.14 T GAF domain-containing protein
KCBGAEBN_00687 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KCBGAEBN_00688 3.4e-24 yueI S Protein of unknown function (DUF1694)
KCBGAEBN_00689 5.1e-184 rarA L recombination factor protein RarA
KCBGAEBN_00691 3.2e-73 usp6 T universal stress protein
KCBGAEBN_00692 3.7e-54 tag 3.2.2.20 L glycosylase
KCBGAEBN_00693 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KCBGAEBN_00694 5.9e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KCBGAEBN_00696 3.3e-75 yviA S Protein of unknown function (DUF421)
KCBGAEBN_00697 1.8e-27 S Protein of unknown function (DUF3290)
KCBGAEBN_00698 2.3e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
KCBGAEBN_00699 1.2e-296 S membrane
KCBGAEBN_00700 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCBGAEBN_00701 4e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
KCBGAEBN_00702 6.5e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
KCBGAEBN_00703 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KCBGAEBN_00705 1.4e-16
KCBGAEBN_00706 2.1e-199 oatA I Acyltransferase
KCBGAEBN_00707 1.8e-213 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCBGAEBN_00708 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KCBGAEBN_00709 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCBGAEBN_00712 5.1e-42 S Phosphoesterase
KCBGAEBN_00713 2.2e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCBGAEBN_00714 1.1e-60 yslB S Protein of unknown function (DUF2507)
KCBGAEBN_00715 9.9e-41 trxA O Belongs to the thioredoxin family
KCBGAEBN_00716 3.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KCBGAEBN_00717 7.5e-15 cvpA S Colicin V production protein
KCBGAEBN_00718 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KCBGAEBN_00719 1.9e-33 yrzB S Belongs to the UPF0473 family
KCBGAEBN_00720 1e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCBGAEBN_00721 2.1e-36 yrzL S Belongs to the UPF0297 family
KCBGAEBN_00722 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KCBGAEBN_00723 3.9e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KCBGAEBN_00724 2.1e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KCBGAEBN_00725 7.5e-13
KCBGAEBN_00726 2.1e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCBGAEBN_00727 3.2e-66 yrjD S LUD domain
KCBGAEBN_00728 2.1e-245 lutB C 4Fe-4S dicluster domain
KCBGAEBN_00729 6.9e-117 lutA C Cysteine-rich domain
KCBGAEBN_00730 2e-208 yfnA E Amino Acid
KCBGAEBN_00732 4.3e-61 uspA T universal stress protein
KCBGAEBN_00734 1.8e-12 yajC U Preprotein translocase
KCBGAEBN_00735 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KCBGAEBN_00736 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCBGAEBN_00737 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KCBGAEBN_00738 7.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KCBGAEBN_00739 6e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCBGAEBN_00740 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCBGAEBN_00741 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
KCBGAEBN_00742 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCBGAEBN_00743 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCBGAEBN_00744 2.9e-64 ymfM S Helix-turn-helix domain
KCBGAEBN_00745 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
KCBGAEBN_00746 3.4e-52 ymfH S Peptidase M16
KCBGAEBN_00747 1.7e-91 ymfH S Peptidase M16
KCBGAEBN_00748 3.5e-108 ymfF S Peptidase M16 inactive domain protein
KCBGAEBN_00749 1.6e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
KCBGAEBN_00750 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KCBGAEBN_00751 1.7e-98 rrmA 2.1.1.187 H Methyltransferase
KCBGAEBN_00752 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
KCBGAEBN_00753 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KCBGAEBN_00754 4.3e-169 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KCBGAEBN_00755 3.2e-21 cutC P Participates in the control of copper homeostasis
KCBGAEBN_00756 3.4e-130 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KCBGAEBN_00757 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KCBGAEBN_00758 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCBGAEBN_00759 5.3e-68 ybbR S YbbR-like protein
KCBGAEBN_00760 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KCBGAEBN_00761 2.4e-71 S Protein of unknown function (DUF1361)
KCBGAEBN_00762 1.2e-115 murB 1.3.1.98 M Cell wall formation
KCBGAEBN_00763 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
KCBGAEBN_00764 2.5e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KCBGAEBN_00765 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KCBGAEBN_00766 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCBGAEBN_00767 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
KCBGAEBN_00768 9.1e-42 yxjI
KCBGAEBN_00769 9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KCBGAEBN_00770 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KCBGAEBN_00771 2.8e-19 secG U Preprotein translocase
KCBGAEBN_00772 7e-180 clcA P chloride
KCBGAEBN_00773 6.7e-146 lmrP E Major Facilitator Superfamily
KCBGAEBN_00774 1.8e-169 T PhoQ Sensor
KCBGAEBN_00775 5e-104 K response regulator
KCBGAEBN_00776 3.3e-119 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCBGAEBN_00777 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KCBGAEBN_00778 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KCBGAEBN_00779 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KCBGAEBN_00780 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KCBGAEBN_00781 1.1e-136 cggR K Putative sugar-binding domain
KCBGAEBN_00783 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KCBGAEBN_00784 6.7e-149 whiA K May be required for sporulation
KCBGAEBN_00785 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KCBGAEBN_00786 7.5e-126 rapZ S Displays ATPase and GTPase activities
KCBGAEBN_00787 2.7e-36 ylbE GM NAD dependent epimerase dehydratase family protein
KCBGAEBN_00788 2.9e-32 ylbE GM NAD(P)H-binding
KCBGAEBN_00789 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KCBGAEBN_00790 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KCBGAEBN_00791 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KCBGAEBN_00792 3.9e-272 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KCBGAEBN_00793 1.9e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCBGAEBN_00794 9.6e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KCBGAEBN_00795 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KCBGAEBN_00796 3.2e-08 KT PspC domain protein
KCBGAEBN_00797 3.5e-85 phoR 2.7.13.3 T Histidine kinase
KCBGAEBN_00798 4.6e-86 K response regulator
KCBGAEBN_00799 4.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
KCBGAEBN_00800 1.2e-162 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KCBGAEBN_00801 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KCBGAEBN_00802 1.7e-96 yeaN P Major Facilitator Superfamily
KCBGAEBN_00803 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KCBGAEBN_00804 1e-45 comFC S Competence protein
KCBGAEBN_00805 4.6e-127 comFA L Helicase C-terminal domain protein
KCBGAEBN_00806 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
KCBGAEBN_00807 4.1e-296 ydaO E amino acid
KCBGAEBN_00808 2.8e-268 aha1 P COG COG0474 Cation transport ATPase
KCBGAEBN_00809 3.7e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KCBGAEBN_00810 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KCBGAEBN_00811 8.2e-34 S CAAX protease self-immunity
KCBGAEBN_00812 1.3e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KCBGAEBN_00813 1.9e-254 uup S ABC transporter, ATP-binding protein
KCBGAEBN_00814 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KCBGAEBN_00815 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KCBGAEBN_00816 2.8e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KCBGAEBN_00817 1.6e-140 ansA 3.5.1.1 EJ Asparaginase
KCBGAEBN_00818 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
KCBGAEBN_00819 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KCBGAEBN_00820 1.4e-40 yabA L Involved in initiation control of chromosome replication
KCBGAEBN_00821 5.2e-83 holB 2.7.7.7 L DNA polymerase III
KCBGAEBN_00822 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCBGAEBN_00823 9.2e-29 yaaL S Protein of unknown function (DUF2508)
KCBGAEBN_00824 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KCBGAEBN_00825 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KCBGAEBN_00826 5.1e-211 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCBGAEBN_00827 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KCBGAEBN_00828 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
KCBGAEBN_00829 3.5e-27 nrdH O Glutaredoxin
KCBGAEBN_00830 4.8e-45 nrdI F NrdI Flavodoxin like
KCBGAEBN_00831 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCBGAEBN_00832 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCBGAEBN_00833 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCBGAEBN_00834 1.4e-54
KCBGAEBN_00835 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KCBGAEBN_00836 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KCBGAEBN_00837 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KCBGAEBN_00838 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCBGAEBN_00839 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
KCBGAEBN_00840 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KCBGAEBN_00841 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KCBGAEBN_00842 7e-71 yacP S YacP-like NYN domain
KCBGAEBN_00843 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCBGAEBN_00844 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KCBGAEBN_00845 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCBGAEBN_00846 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCBGAEBN_00847 8.2e-154 yacL S domain protein
KCBGAEBN_00848 1e-222 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KCBGAEBN_00849 6.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KCBGAEBN_00850 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
KCBGAEBN_00851 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
KCBGAEBN_00852 1e-33 S Enterocin A Immunity
KCBGAEBN_00853 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KCBGAEBN_00854 4.5e-129 mleP2 S Sodium Bile acid symporter family
KCBGAEBN_00855 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCBGAEBN_00857 3e-43 ydcK S Belongs to the SprT family
KCBGAEBN_00858 4.4e-252 yhgF K Tex-like protein N-terminal domain protein
KCBGAEBN_00859 1e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KCBGAEBN_00860 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCBGAEBN_00861 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KCBGAEBN_00862 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
KCBGAEBN_00863 1e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCBGAEBN_00865 1.1e-07
KCBGAEBN_00866 1.6e-197 dtpT U amino acid peptide transporter
KCBGAEBN_00868 3.8e-93 yihY S Belongs to the UPF0761 family
KCBGAEBN_00869 6.2e-12 mltD CBM50 M Lysin motif
KCBGAEBN_00870 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KCBGAEBN_00871 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
KCBGAEBN_00872 5.1e-54 fld C Flavodoxin
KCBGAEBN_00873 8.7e-53 gtcA S Teichoic acid glycosylation protein
KCBGAEBN_00874 0.0 S Bacterial membrane protein YfhO
KCBGAEBN_00875 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
KCBGAEBN_00876 1.7e-122 S Sulfite exporter TauE/SafE
KCBGAEBN_00877 2.4e-70 K Sugar-specific transcriptional regulator TrmB
KCBGAEBN_00878 1e-167 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KCBGAEBN_00879 6e-182 pepS E Thermophilic metalloprotease (M29)
KCBGAEBN_00880 3e-266 E Amino acid permease
KCBGAEBN_00881 4.9e-85 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KCBGAEBN_00882 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KCBGAEBN_00883 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
KCBGAEBN_00884 4.3e-213 malT G Transporter, major facilitator family protein
KCBGAEBN_00885 3.1e-43 malR K Transcriptional regulator, LacI family
KCBGAEBN_00886 6.6e-37 malR K Transcriptional regulator, LacI family
KCBGAEBN_00887 2.3e-279 kup P Transport of potassium into the cell
KCBGAEBN_00889 2e-20 S Domain of unknown function (DUF3284)
KCBGAEBN_00890 5.2e-160 yfmL L DEAD DEAH box helicase
KCBGAEBN_00891 1.6e-127 mocA S Oxidoreductase
KCBGAEBN_00892 2e-24 S Domain of unknown function (DUF4828)
KCBGAEBN_00893 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
KCBGAEBN_00894 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KCBGAEBN_00895 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
KCBGAEBN_00896 1.4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
KCBGAEBN_00897 7.1e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KCBGAEBN_00898 3.6e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KCBGAEBN_00899 8.5e-222 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KCBGAEBN_00900 1.1e-41 O ADP-ribosylglycohydrolase
KCBGAEBN_00901 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
KCBGAEBN_00902 2.9e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KCBGAEBN_00903 1.3e-34 K GNAT family
KCBGAEBN_00904 1.7e-40
KCBGAEBN_00906 2.1e-159 mgtE P Acts as a magnesium transporter
KCBGAEBN_00907 9.7e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
KCBGAEBN_00908 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KCBGAEBN_00909 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
KCBGAEBN_00910 2.7e-259 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KCBGAEBN_00911 9.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KCBGAEBN_00912 9.7e-194 pbuX F xanthine permease
KCBGAEBN_00913 3.3e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KCBGAEBN_00914 4.1e-60 acmC 3.2.1.96 NU mannosyl-glycoprotein
KCBGAEBN_00915 9.4e-64 S ECF transporter, substrate-specific component
KCBGAEBN_00916 3.3e-127 mleP S Sodium Bile acid symporter family
KCBGAEBN_00917 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KCBGAEBN_00918 6.2e-72 mleR K LysR family
KCBGAEBN_00919 1.1e-56 K transcriptional
KCBGAEBN_00920 3.4e-41 K Bacterial regulatory proteins, tetR family
KCBGAEBN_00921 1.8e-59 T Belongs to the universal stress protein A family
KCBGAEBN_00922 3.6e-44 K Copper transport repressor CopY TcrY
KCBGAEBN_00923 3.5e-230 3.2.1.18 GH33 M Rib/alpha-like repeat
KCBGAEBN_00925 1.8e-95 ypuA S Protein of unknown function (DUF1002)
KCBGAEBN_00926 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
KCBGAEBN_00927 3e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCBGAEBN_00928 8.7e-35 yncA 2.3.1.79 S Maltose acetyltransferase
KCBGAEBN_00929 6.9e-206 yflS P Sodium:sulfate symporter transmembrane region
KCBGAEBN_00930 1.2e-199 frdC 1.3.5.4 C FAD binding domain
KCBGAEBN_00931 3.3e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KCBGAEBN_00932 2e-14 ybaN S Protein of unknown function (DUF454)
KCBGAEBN_00933 8.2e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KCBGAEBN_00934 2.6e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KCBGAEBN_00935 3.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCBGAEBN_00936 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KCBGAEBN_00937 1.1e-71 ywlG S Belongs to the UPF0340 family
KCBGAEBN_00938 7.3e-67 S Acetyltransferase (GNAT) domain
KCBGAEBN_00939 9.2e-14 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KCBGAEBN_00942 2.3e-173 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
KCBGAEBN_00943 3e-230 yfjM S Protein of unknown function DUF262
KCBGAEBN_00944 8.5e-73 S Domain of unknown function (DUF3841)
KCBGAEBN_00945 1.6e-56 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
KCBGAEBN_00946 4.2e-302 hsdM 2.1.1.72 V Type I restriction-modification system
KCBGAEBN_00947 1.4e-208 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCBGAEBN_00948 3.4e-146 yegS 2.7.1.107 G Lipid kinase
KCBGAEBN_00949 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCBGAEBN_00950 3.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KCBGAEBN_00951 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCBGAEBN_00952 1.2e-160 camS S sex pheromone
KCBGAEBN_00953 3.9e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCBGAEBN_00954 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KCBGAEBN_00955 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KCBGAEBN_00958 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KCBGAEBN_00959 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCBGAEBN_00960 2.4e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCBGAEBN_00961 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCBGAEBN_00962 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KCBGAEBN_00963 5.5e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KCBGAEBN_00964 1.1e-40 yabR J RNA binding
KCBGAEBN_00965 1.3e-21 divIC D Septum formation initiator
KCBGAEBN_00966 3.6e-31 yabO J S4 domain protein
KCBGAEBN_00967 7.3e-140 yabM S Polysaccharide biosynthesis protein
KCBGAEBN_00968 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCBGAEBN_00969 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KCBGAEBN_00970 6.2e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KCBGAEBN_00971 2.5e-86 S (CBS) domain
KCBGAEBN_00972 4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCBGAEBN_00973 3.2e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCBGAEBN_00974 1e-51 perR P Belongs to the Fur family
KCBGAEBN_00975 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
KCBGAEBN_00976 6.7e-97 sbcC L Putative exonuclease SbcCD, C subunit
KCBGAEBN_00977 1.1e-113 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KCBGAEBN_00978 2.1e-36 M LysM domain protein
KCBGAEBN_00979 3e-278 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KCBGAEBN_00980 7e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KCBGAEBN_00981 2e-35 ygfC K Bacterial regulatory proteins, tetR family
KCBGAEBN_00982 5.9e-101 hrtB V ABC transporter permease
KCBGAEBN_00983 1.5e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KCBGAEBN_00984 3e-67 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KCBGAEBN_00985 0.0 helD 3.6.4.12 L DNA helicase
KCBGAEBN_00986 8.9e-246 yjbQ P TrkA C-terminal domain protein
KCBGAEBN_00987 3.4e-23
KCBGAEBN_00988 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
KCBGAEBN_00989 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KCBGAEBN_00990 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KCBGAEBN_00991 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCBGAEBN_00992 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCBGAEBN_00993 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCBGAEBN_00994 4.8e-53 rplQ J Ribosomal protein L17
KCBGAEBN_00995 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCBGAEBN_00996 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KCBGAEBN_00997 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KCBGAEBN_00998 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KCBGAEBN_00999 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KCBGAEBN_01000 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KCBGAEBN_01001 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KCBGAEBN_01002 1e-67 rplO J Binds to the 23S rRNA
KCBGAEBN_01003 2.1e-22 rpmD J Ribosomal protein L30
KCBGAEBN_01004 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KCBGAEBN_01005 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KCBGAEBN_01006 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KCBGAEBN_01007 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KCBGAEBN_01008 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCBGAEBN_01009 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCBGAEBN_01010 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCBGAEBN_01011 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KCBGAEBN_01012 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCBGAEBN_01013 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
KCBGAEBN_01014 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KCBGAEBN_01015 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KCBGAEBN_01016 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KCBGAEBN_01017 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KCBGAEBN_01018 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCBGAEBN_01019 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KCBGAEBN_01020 1e-100 rplD J Forms part of the polypeptide exit tunnel
KCBGAEBN_01021 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KCBGAEBN_01022 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KCBGAEBN_01023 5.6e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCBGAEBN_01024 2.5e-78 K rpiR family
KCBGAEBN_01025 5.9e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KCBGAEBN_01026 1.1e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
KCBGAEBN_01027 6.5e-21 K Acetyltransferase (GNAT) domain
KCBGAEBN_01028 2.9e-182 steT E amino acid
KCBGAEBN_01029 9.6e-78 glnP P ABC transporter permease
KCBGAEBN_01030 1.2e-85 gluC P ABC transporter permease
KCBGAEBN_01031 6.6e-100 glnH ET ABC transporter
KCBGAEBN_01032 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KCBGAEBN_01033 3.9e-08
KCBGAEBN_01034 2.2e-98
KCBGAEBN_01036 3.2e-53 zur P Belongs to the Fur family
KCBGAEBN_01037 2.2e-212 yfnA E Amino Acid
KCBGAEBN_01038 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KCBGAEBN_01039 0.0 L Helicase C-terminal domain protein
KCBGAEBN_01040 6e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
KCBGAEBN_01041 2.1e-180 yhdP S Transporter associated domain
KCBGAEBN_01042 1.7e-26
KCBGAEBN_01043 5.3e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCBGAEBN_01044 3.7e-131 bacI V MacB-like periplasmic core domain
KCBGAEBN_01045 7.4e-97 V ABC transporter
KCBGAEBN_01046 2.6e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCBGAEBN_01047 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
KCBGAEBN_01048 6.2e-140 V MatE
KCBGAEBN_01049 3.5e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KCBGAEBN_01050 2.1e-85 S Alpha beta hydrolase
KCBGAEBN_01051 7.1e-95 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KCBGAEBN_01052 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCBGAEBN_01053 1e-111 argE 3.5.1.18 E Peptidase dimerisation domain
KCBGAEBN_01054 8.4e-102 IQ Enoyl-(Acyl carrier protein) reductase
KCBGAEBN_01055 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
KCBGAEBN_01056 8.1e-53 queT S QueT transporter
KCBGAEBN_01058 1.1e-65 degV S Uncharacterised protein, DegV family COG1307
KCBGAEBN_01059 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KCBGAEBN_01060 9.4e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KCBGAEBN_01061 3.2e-34 trxA O Belongs to the thioredoxin family
KCBGAEBN_01062 1.4e-86 S Sucrose-6F-phosphate phosphohydrolase
KCBGAEBN_01063 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KCBGAEBN_01064 2.8e-49 S Threonine/Serine exporter, ThrE
KCBGAEBN_01065 4.3e-82 thrE S Putative threonine/serine exporter
KCBGAEBN_01066 3.1e-27 cspC K Cold shock protein
KCBGAEBN_01067 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
KCBGAEBN_01068 3.8e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KCBGAEBN_01069 5.4e-23
KCBGAEBN_01070 1.2e-58 3.6.1.27 I phosphatase
KCBGAEBN_01071 1.2e-24
KCBGAEBN_01072 1.8e-65 I alpha/beta hydrolase fold
KCBGAEBN_01073 1.3e-38 azlD S branched-chain amino acid
KCBGAEBN_01074 1.1e-104 azlC E AzlC protein
KCBGAEBN_01075 1.3e-16
KCBGAEBN_01076 1.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
KCBGAEBN_01077 3.8e-99 V domain protein
KCBGAEBN_01078 1.9e-09
KCBGAEBN_01080 6e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KCBGAEBN_01081 5.4e-172 malY 4.4.1.8 E Aminotransferase, class I
KCBGAEBN_01082 2.4e-118 K AI-2E family transporter
KCBGAEBN_01083 5.2e-61 EG EamA-like transporter family
KCBGAEBN_01084 1.1e-75 L haloacid dehalogenase-like hydrolase
KCBGAEBN_01085 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KCBGAEBN_01086 1.8e-67 1.5.1.38 S NADPH-dependent FMN reductase
KCBGAEBN_01087 1.2e-08 L Probable transposase
KCBGAEBN_01088 3.7e-164 C Luciferase-like monooxygenase
KCBGAEBN_01089 1.3e-41 K Transcriptional regulator, HxlR family
KCBGAEBN_01090 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCBGAEBN_01091 6.2e-102 ydhQ K UbiC transcription regulator-associated domain protein
KCBGAEBN_01092 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KCBGAEBN_01093 2.4e-82 pncA Q isochorismatase
KCBGAEBN_01094 3.5e-63 3.1.3.73 G phosphoglycerate mutase
KCBGAEBN_01095 4e-104 treB G phosphotransferase system
KCBGAEBN_01096 1.1e-147 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
KCBGAEBN_01097 1.9e-167 mdtG EGP Major facilitator Superfamily
KCBGAEBN_01099 5.6e-194 XK27_08315 M Sulfatase
KCBGAEBN_01100 1.6e-47 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KCBGAEBN_01101 1.1e-216 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KCBGAEBN_01102 7.2e-149 mepA V MATE efflux family protein
KCBGAEBN_01103 5.6e-150 lsa S ABC transporter
KCBGAEBN_01104 4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCBGAEBN_01105 6.8e-109 puuD S peptidase C26
KCBGAEBN_01106 9.8e-202 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KCBGAEBN_01107 1.1e-25
KCBGAEBN_01108 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
KCBGAEBN_01109 2.9e-60 uspA T Universal stress protein family
KCBGAEBN_01111 4.7e-210 glnP P ABC transporter
KCBGAEBN_01112 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KCBGAEBN_01113 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KCBGAEBN_01114 8.8e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KCBGAEBN_01115 3.4e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KCBGAEBN_01116 4.1e-177 thrC 4.2.3.1 E Threonine synthase
KCBGAEBN_01117 9.7e-75 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KCBGAEBN_01118 2e-60 S Psort location CytoplasmicMembrane, score
KCBGAEBN_01119 1.3e-87 waaB GT4 M Glycosyl transferases group 1
KCBGAEBN_01120 1.4e-58 cps3F
KCBGAEBN_01121 5.3e-70 M Domain of unknown function (DUF4422)
KCBGAEBN_01122 4.8e-161 XK27_08315 M Sulfatase
KCBGAEBN_01123 6.5e-130 S Bacterial membrane protein YfhO
KCBGAEBN_01124 3.6e-14
KCBGAEBN_01125 1.4e-54 cps3I G Acyltransferase family
KCBGAEBN_01126 1.1e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KCBGAEBN_01127 4.4e-39 2.7.7.65 T phosphorelay sensor kinase activity
KCBGAEBN_01128 1.1e-157 XK27_09615 S reductase
KCBGAEBN_01129 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
KCBGAEBN_01130 1.8e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCBGAEBN_01131 2.8e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KCBGAEBN_01132 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KCBGAEBN_01133 1.2e-74 G Peptidase_C39 like family
KCBGAEBN_01134 8.3e-48 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KCBGAEBN_01135 1e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KCBGAEBN_01136 2.3e-133 coaA 2.7.1.33 F Pantothenic acid kinase
KCBGAEBN_01137 3.5e-42 E lipolytic protein G-D-S-L family
KCBGAEBN_01138 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KCBGAEBN_01139 2.1e-189 glnPH2 P ABC transporter permease
KCBGAEBN_01140 2.1e-213 yjeM E Amino Acid
KCBGAEBN_01141 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
KCBGAEBN_01142 5.1e-138 tetA EGP Major facilitator Superfamily
KCBGAEBN_01144 3.1e-70 rny D Peptidase family M23
KCBGAEBN_01145 8.5e-188 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
KCBGAEBN_01146 1.1e-193 glf 5.4.99.9 M UDP-galactopyranose mutase
KCBGAEBN_01147 1.8e-116 M Core-2/I-Branching enzyme
KCBGAEBN_01148 8.5e-90 rfbP M Bacterial sugar transferase
KCBGAEBN_01149 3.7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KCBGAEBN_01150 8.6e-110 ywqE 3.1.3.48 GM PHP domain protein
KCBGAEBN_01151 1.2e-81 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KCBGAEBN_01152 3e-73 epsB M biosynthesis protein
KCBGAEBN_01154 2.7e-114 cps2J S Polysaccharide biosynthesis protein
KCBGAEBN_01155 1.2e-67 S Polysaccharide pyruvyl transferase
KCBGAEBN_01157 4.5e-28 M family 8
KCBGAEBN_01158 6.5e-59
KCBGAEBN_01159 5.9e-37 M group 2 family protein
KCBGAEBN_01160 1e-91 M Glycosyl transferase family 8
KCBGAEBN_01161 5.9e-114 3.6.4.12 L UvrD/REP helicase N-terminal domain
KCBGAEBN_01162 4.8e-144 L AAA ATPase domain
KCBGAEBN_01163 4.9e-79 S response to antibiotic
KCBGAEBN_01164 9.8e-27 S zinc-ribbon domain
KCBGAEBN_01165 1.6e-117 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
KCBGAEBN_01166 2.1e-130 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KCBGAEBN_01167 5.6e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KCBGAEBN_01168 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KCBGAEBN_01169 1.9e-142 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCBGAEBN_01170 1.7e-62 S Glycosyltransferase like family 2
KCBGAEBN_01171 2.2e-116 cps1D M Domain of unknown function (DUF4422)
KCBGAEBN_01172 7.3e-38 S CAAX protease self-immunity
KCBGAEBN_01173 1e-87 yvyE 3.4.13.9 S YigZ family
KCBGAEBN_01174 3.3e-57 S Haloacid dehalogenase-like hydrolase
KCBGAEBN_01175 3.4e-154 EGP Major facilitator Superfamily
KCBGAEBN_01177 2.2e-66 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KCBGAEBN_01178 1.2e-27 yraB K transcriptional regulator
KCBGAEBN_01179 9.8e-90 S NADPH-dependent FMN reductase
KCBGAEBN_01180 1.7e-100 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KCBGAEBN_01181 8.6e-56 S ECF transporter, substrate-specific component
KCBGAEBN_01182 2.8e-95 znuB U ABC 3 transport family
KCBGAEBN_01183 1e-98 fhuC P ABC transporter
KCBGAEBN_01184 5.1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
KCBGAEBN_01185 1.3e-40
KCBGAEBN_01186 5e-51 I Alpha/beta hydrolase family
KCBGAEBN_01187 1.8e-94 S Bacterial membrane protein, YfhO
KCBGAEBN_01188 5.5e-53 XK27_01040 S Protein of unknown function (DUF1129)
KCBGAEBN_01189 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KCBGAEBN_01190 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
KCBGAEBN_01191 1.4e-108 spo0J K Belongs to the ParB family
KCBGAEBN_01192 6.5e-118 soj D Sporulation initiation inhibitor
KCBGAEBN_01193 3.7e-82 noc K Belongs to the ParB family
KCBGAEBN_01194 1.1e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KCBGAEBN_01195 4.1e-127 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KCBGAEBN_01196 2.7e-108 3.1.4.46 C phosphodiesterase
KCBGAEBN_01197 0.0 pacL 3.6.3.8 P P-type ATPase
KCBGAEBN_01198 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
KCBGAEBN_01199 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KCBGAEBN_01201 2.3e-63 srtA 3.4.22.70 M sortase family
KCBGAEBN_01202 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KCBGAEBN_01203 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KCBGAEBN_01204 3.7e-34
KCBGAEBN_01205 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCBGAEBN_01206 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCBGAEBN_01207 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KCBGAEBN_01208 4.7e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCBGAEBN_01209 1.1e-39 ybjQ S Belongs to the UPF0145 family
KCBGAEBN_01210 2.5e-08
KCBGAEBN_01211 8e-96 V ABC transporter, ATP-binding protein
KCBGAEBN_01212 1.1e-41 gntR1 K Transcriptional regulator, GntR family
KCBGAEBN_01213 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
KCBGAEBN_01214 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KCBGAEBN_01215 4.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
KCBGAEBN_01216 2.2e-107 terC P Integral membrane protein TerC family
KCBGAEBN_01217 1.6e-38 K Transcriptional regulator
KCBGAEBN_01218 5.7e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KCBGAEBN_01219 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KCBGAEBN_01220 4.5e-102 tcyB E ABC transporter
KCBGAEBN_01221 3.2e-29 ponA V the current gene model (or a revised gene model) may contain a frame shift
KCBGAEBN_01222 4.7e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KCBGAEBN_01223 1.5e-301 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KCBGAEBN_01224 2e-209 mtlR K Mga helix-turn-helix domain
KCBGAEBN_01225 7.5e-177 yjcE P Sodium proton antiporter
KCBGAEBN_01226 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KCBGAEBN_01227 4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
KCBGAEBN_01228 9.5e-69 dhaL 2.7.1.121 S Dak2
KCBGAEBN_01229 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
KCBGAEBN_01230 9.3e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
KCBGAEBN_01231 1.7e-61 K Bacterial regulatory proteins, tetR family
KCBGAEBN_01232 3.2e-208 brnQ U Component of the transport system for branched-chain amino acids
KCBGAEBN_01234 3.7e-111 endA F DNA RNA non-specific endonuclease
KCBGAEBN_01235 4.1e-75 XK27_02070 S Nitroreductase family
KCBGAEBN_01236 3.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
KCBGAEBN_01237 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
KCBGAEBN_01238 5.2e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
KCBGAEBN_01239 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KCBGAEBN_01240 9.3e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
KCBGAEBN_01241 5.1e-77 azlC E branched-chain amino acid
KCBGAEBN_01242 2e-31 azlD S Branched-chain amino acid transport protein (AzlD)
KCBGAEBN_01243 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
KCBGAEBN_01244 1.6e-55 jag S R3H domain protein
KCBGAEBN_01245 1.2e-123 sip L Belongs to the 'phage' integrase family
KCBGAEBN_01246 1.4e-24 K Cro/C1-type HTH DNA-binding domain
KCBGAEBN_01247 2.5e-08 S Helix-turn-helix domain
KCBGAEBN_01249 6.8e-39 K COG3617 Prophage antirepressor
KCBGAEBN_01254 6.7e-15
KCBGAEBN_01255 3.1e-43 L Bifunctional DNA primase/polymerase, N-terminal
KCBGAEBN_01256 1e-76 S DNA primase
KCBGAEBN_01258 1.1e-08
KCBGAEBN_01261 6.9e-54 K Transcriptional regulator C-terminal region
KCBGAEBN_01262 7.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
KCBGAEBN_01263 2.6e-285 pepO 3.4.24.71 O Peptidase family M13
KCBGAEBN_01264 1.7e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
KCBGAEBN_01265 1.7e-09 yvaZ S Protein of unknown function (DUF1648)
KCBGAEBN_01266 6.2e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KCBGAEBN_01267 3.9e-47 hmpT S ECF-type riboflavin transporter, S component
KCBGAEBN_01268 5.1e-42 wecD K Acetyltransferase GNAT Family
KCBGAEBN_01270 2.5e-254 XK27_06780 V ABC transporter permease
KCBGAEBN_01271 6.4e-96 XK27_06785 V ABC transporter, ATP-binding protein
KCBGAEBN_01273 7.5e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KCBGAEBN_01274 6.9e-121 ytbE S reductase
KCBGAEBN_01275 4.2e-43 ytcD K HxlR-like helix-turn-helix
KCBGAEBN_01276 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
KCBGAEBN_01277 2e-67 ybbL S ABC transporter
KCBGAEBN_01278 8.1e-163 oxlT P Major Facilitator Superfamily
KCBGAEBN_01279 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KCBGAEBN_01280 3.1e-47 S Short repeat of unknown function (DUF308)
KCBGAEBN_01281 1.4e-30 tetR K Transcriptional regulator C-terminal region
KCBGAEBN_01282 1.2e-150 yfeX P Peroxidase
KCBGAEBN_01283 2.5e-16 S Protein of unknown function (DUF3021)
KCBGAEBN_01284 4.5e-39 K LytTr DNA-binding domain
KCBGAEBN_01285 7.6e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KCBGAEBN_01286 8.4e-209 mmuP E amino acid
KCBGAEBN_01287 1.2e-15 psiE S Phosphate-starvation-inducible E
KCBGAEBN_01288 3.7e-155 oppF P Belongs to the ABC transporter superfamily
KCBGAEBN_01289 7.4e-181 oppD P Belongs to the ABC transporter superfamily
KCBGAEBN_01290 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCBGAEBN_01291 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCBGAEBN_01292 1.1e-202 oppA E ABC transporter, substratebinding protein
KCBGAEBN_01293 1.2e-218 yifK E Amino acid permease
KCBGAEBN_01294 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCBGAEBN_01295 5.1e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
KCBGAEBN_01296 6.5e-66 pgm3 G phosphoglycerate mutase family
KCBGAEBN_01297 1.3e-252 ctpA 3.6.3.54 P P-type ATPase
KCBGAEBN_01298 1.9e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KCBGAEBN_01299 6.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KCBGAEBN_01300 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KCBGAEBN_01301 5.3e-134 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KCBGAEBN_01302 4.3e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KCBGAEBN_01303 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KCBGAEBN_01304 1.6e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KCBGAEBN_01305 2.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
KCBGAEBN_01306 1.2e-197 1.3.5.4 C FMN_bind
KCBGAEBN_01307 2.2e-56 3.1.3.48 K Transcriptional regulator
KCBGAEBN_01308 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KCBGAEBN_01309 4.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
KCBGAEBN_01310 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KCBGAEBN_01311 9.3e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
KCBGAEBN_01312 1.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KCBGAEBN_01313 2.8e-81 S Belongs to the UPF0246 family
KCBGAEBN_01314 5.6e-10 S CAAX protease self-immunity
KCBGAEBN_01315 3.5e-59 ykhA 3.1.2.20 I Thioesterase superfamily
KCBGAEBN_01316 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KCBGAEBN_01318 7.4e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCBGAEBN_01319 5.3e-64 C FMN binding
KCBGAEBN_01320 1.3e-204 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KCBGAEBN_01321 1.7e-54 rplI J Binds to the 23S rRNA
KCBGAEBN_01322 2.3e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KCBGAEBN_01323 3.6e-07
KCBGAEBN_01329 5.1e-08
KCBGAEBN_01331 2.8e-182 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KCBGAEBN_01332 9.1e-31 L Helix-turn-helix domain
KCBGAEBN_01333 3.1e-72 L HTH-like domain
KCBGAEBN_01334 3.5e-23 L PLD-like domain
KCBGAEBN_01335 6.5e-12 L PLD-like domain
KCBGAEBN_01337 6.1e-08 yokH G regulation of fungal-type cell wall biogenesis
KCBGAEBN_01338 9.4e-109 L Initiator Replication protein
KCBGAEBN_01339 1.9e-37 S Replication initiator protein A (RepA) N-terminus
KCBGAEBN_01340 8.5e-141 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCBGAEBN_01341 3.2e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KCBGAEBN_01342 1.4e-12 bglG K antiterminator
KCBGAEBN_01343 2.9e-124 D CobQ CobB MinD ParA nucleotide binding domain protein
KCBGAEBN_01345 1.1e-35
KCBGAEBN_01346 0.0 pepN 3.4.11.2 E aminopeptidase
KCBGAEBN_01347 1.8e-43 2.7.13.3 T protein histidine kinase activity
KCBGAEBN_01348 1.6e-22 agrA KT Response regulator of the LytR AlgR family
KCBGAEBN_01350 1.3e-16 M domain protein
KCBGAEBN_01355 3.6e-125 yvgN C Aldo keto reductase
KCBGAEBN_01356 1.7e-122 yvgN C Aldo keto reductase
KCBGAEBN_01357 2.2e-70 K DeoR C terminal sensor domain
KCBGAEBN_01358 1.1e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KCBGAEBN_01359 3.4e-41 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
KCBGAEBN_01360 1.2e-216 pts36C G PTS system sugar-specific permease component
KCBGAEBN_01362 2.3e-104 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
KCBGAEBN_01364 6.2e-29 S COG NOG19168 non supervised orthologous group
KCBGAEBN_01365 1.1e-189 XK27_11280 S Psort location CytoplasmicMembrane, score
KCBGAEBN_01366 2.7e-14 L Plasmid pRiA4b ORF-3-like protein
KCBGAEBN_01367 1.5e-105 L Belongs to the 'phage' integrase family
KCBGAEBN_01368 5.7e-23 3.1.21.3 V Type I restriction modification DNA specificity domain
KCBGAEBN_01369 8.6e-60 hsdM 2.1.1.72 V type I restriction-modification system
KCBGAEBN_01371 1.5e-54 sthIM 2.1.1.72 L DNA methylase
KCBGAEBN_01372 2.4e-09 sthIM 2.1.1.72 L DNA methylase
KCBGAEBN_01373 6.3e-109 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KCBGAEBN_01374 5.9e-57 sthIM 2.1.1.72 L DNA methylase
KCBGAEBN_01375 3.7e-105 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KCBGAEBN_01376 4e-260 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
KCBGAEBN_01377 4.6e-16
KCBGAEBN_01378 4.9e-24
KCBGAEBN_01379 3.4e-48 L HNH endonuclease
KCBGAEBN_01382 3.5e-133 potE2 E amino acid
KCBGAEBN_01383 4.8e-71 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KCBGAEBN_01384 2.3e-69 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KCBGAEBN_01385 7.2e-117 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCBGAEBN_01386 1.9e-57 racA K Domain of unknown function (DUF1836)
KCBGAEBN_01387 3.1e-81 yitS S EDD domain protein, DegV family
KCBGAEBN_01388 1.7e-46 yjaB_1 K Acetyltransferase (GNAT) domain
KCBGAEBN_01391 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KCBGAEBN_01392 0.0 O Belongs to the peptidase S8 family
KCBGAEBN_01393 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
KCBGAEBN_01394 2.5e-58 tlpA2 L Transposase IS200 like
KCBGAEBN_01395 1.1e-157 L transposase, IS605 OrfB family
KCBGAEBN_01396 4.6e-84 dps P Ferritin-like domain
KCBGAEBN_01397 1.1e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
KCBGAEBN_01398 9.6e-44 L hmm pf00665
KCBGAEBN_01399 5e-18 tnp
KCBGAEBN_01400 8.7e-31 tnp L Transposase IS66 family
KCBGAEBN_01401 1.7e-32 P Heavy-metal-associated domain
KCBGAEBN_01402 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KCBGAEBN_01403 1.3e-20 L PFAM transposase IS3 IS911 family protein
KCBGAEBN_01404 1.4e-41 L Integrase core domain
KCBGAEBN_01405 2.4e-35 L Integrase core domain
KCBGAEBN_01406 7.5e-129 EGP Major Facilitator Superfamily
KCBGAEBN_01407 1.4e-98 EGP Major Facilitator Superfamily
KCBGAEBN_01408 7.5e-73 K Transcriptional regulator, LysR family
KCBGAEBN_01409 4.7e-138 G Xylose isomerase-like TIM barrel
KCBGAEBN_01410 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
KCBGAEBN_01411 4e-216 1.3.5.4 C FAD binding domain
KCBGAEBN_01412 6.5e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCBGAEBN_01413 1e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KCBGAEBN_01414 4.2e-142 xerS L Phage integrase family
KCBGAEBN_01418 1.1e-20 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KCBGAEBN_01419 2.5e-82 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KCBGAEBN_01420 8.2e-13 ptp3 3.1.3.48 T Tyrosine phosphatase family
KCBGAEBN_01421 8.7e-39 ptp3 3.1.3.48 T Tyrosine phosphatase family
KCBGAEBN_01422 2.4e-75 desR K helix_turn_helix, Lux Regulon
KCBGAEBN_01423 8.4e-58 salK 2.7.13.3 T Histidine kinase
KCBGAEBN_01424 3.2e-53 yvfS V ABC-2 type transporter
KCBGAEBN_01425 3.4e-78 yvfR V ABC transporter
KCBGAEBN_01426 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCBGAEBN_01427 1.9e-78 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KCBGAEBN_01428 2.7e-30
KCBGAEBN_01429 3.7e-16
KCBGAEBN_01430 3e-111 rssA S Phospholipase, patatin family
KCBGAEBN_01431 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCBGAEBN_01432 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
KCBGAEBN_01433 5.5e-45 S VIT family
KCBGAEBN_01434 4.2e-240 sufB O assembly protein SufB
KCBGAEBN_01435 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
KCBGAEBN_01436 3.7e-147 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCBGAEBN_01437 4.6e-145 sufD O FeS assembly protein SufD
KCBGAEBN_01438 1.1e-115 sufC O FeS assembly ATPase SufC
KCBGAEBN_01439 1.7e-224 E ABC transporter, substratebinding protein
KCBGAEBN_01440 2.5e-255 V Type II restriction enzyme, methylase subunits
KCBGAEBN_01441 5.6e-136 pfoS S Phosphotransferase system, EIIC
KCBGAEBN_01442 5.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KCBGAEBN_01443 7e-27 L PFAM transposase IS200-family protein
KCBGAEBN_01444 6.3e-64 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
KCBGAEBN_01445 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KCBGAEBN_01446 1.1e-136 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
KCBGAEBN_01447 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
KCBGAEBN_01448 4.5e-43 gutM K Glucitol operon activator protein (GutM)
KCBGAEBN_01449 1.3e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
KCBGAEBN_01450 5.2e-110 IQ NAD dependent epimerase/dehydratase family
KCBGAEBN_01451 1.8e-162 ytbD EGP Major facilitator Superfamily
KCBGAEBN_01452 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
KCBGAEBN_01453 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCBGAEBN_01455 1.1e-265 fbp 3.1.3.11 G phosphatase activity
KCBGAEBN_01456 1.4e-70 xerD L Phage integrase, N-terminal SAM-like domain
KCBGAEBN_01459 2e-86 mesE M Transport protein ComB
KCBGAEBN_01460 1.2e-250 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCBGAEBN_01463 7.3e-56 K LytTr DNA-binding domain
KCBGAEBN_01464 1.8e-51 2.7.13.3 T GHKL domain
KCBGAEBN_01470 9.2e-16
KCBGAEBN_01472 7.2e-08
KCBGAEBN_01473 6.6e-19
KCBGAEBN_01474 5.9e-39 blpT
KCBGAEBN_01475 3e-87 S Haloacid dehalogenase-like hydrolase
KCBGAEBN_01476 1.8e-14
KCBGAEBN_01478 1.8e-28 S Phage gp6-like head-tail connector protein
KCBGAEBN_01479 3.1e-98
KCBGAEBN_01480 4e-08 S Domain of unknown function (DUF4355)
KCBGAEBN_01483 9.5e-17 S head morphogenesis protein, SPP1 gp7 family
KCBGAEBN_01484 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
KCBGAEBN_01485 1.3e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KCBGAEBN_01486 1.3e-66 S Protein of unknown function (DUF1440)
KCBGAEBN_01487 7.7e-41 S Iron-sulfur cluster assembly protein
KCBGAEBN_01488 3.3e-113 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KCBGAEBN_01489 5.9e-75 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KCBGAEBN_01490 5.1e-207 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KCBGAEBN_01491 5.6e-153 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KCBGAEBN_01492 4e-64 G Xylose isomerase domain protein TIM barrel
KCBGAEBN_01493 1.7e-72 nanK GK ROK family
KCBGAEBN_01494 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
KCBGAEBN_01495 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KCBGAEBN_01496 4.3e-75 K Helix-turn-helix domain, rpiR family
KCBGAEBN_01497 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
KCBGAEBN_01498 6.9e-217 yjeM E Amino Acid
KCBGAEBN_01500 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCBGAEBN_01501 3.4e-232 tetP J elongation factor G
KCBGAEBN_01503 1.3e-10 tcdC
KCBGAEBN_01505 7.3e-102 L PLD-like domain
KCBGAEBN_01506 3.9e-147 scrR K helix_turn _helix lactose operon repressor
KCBGAEBN_01507 5.9e-216 scrB 3.2.1.26 GH32 G invertase
KCBGAEBN_01508 1.4e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
KCBGAEBN_01509 2.6e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KCBGAEBN_01510 1.2e-114 ntpJ P Potassium uptake protein
KCBGAEBN_01511 4.8e-58 ktrA P TrkA-N domain
KCBGAEBN_01512 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KCBGAEBN_01513 1.3e-36 M Glycosyltransferase group 2 family protein
KCBGAEBN_01514 1.4e-19
KCBGAEBN_01515 1.8e-94 S Predicted membrane protein (DUF2207)
KCBGAEBN_01516 2.1e-54 bioY S BioY family
KCBGAEBN_01517 2.2e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCBGAEBN_01518 7.6e-74 glcR K DeoR C terminal sensor domain
KCBGAEBN_01519 2.2e-60 yceE S haloacid dehalogenase-like hydrolase
KCBGAEBN_01520 1.1e-41 S CAAX protease self-immunity
KCBGAEBN_01521 9.1e-34 S Domain of unknown function (DUF4811)
KCBGAEBN_01522 2.1e-197 lmrB EGP Major facilitator Superfamily
KCBGAEBN_01523 1.9e-32 merR K MerR HTH family regulatory protein
KCBGAEBN_01524 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KCBGAEBN_01525 1.2e-70 S Protein of unknown function (DUF554)
KCBGAEBN_01526 2.8e-121 G Bacterial extracellular solute-binding protein
KCBGAEBN_01527 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
KCBGAEBN_01528 5.1e-99 baeS T Histidine kinase
KCBGAEBN_01529 1.1e-80 rbsB G sugar-binding domain protein
KCBGAEBN_01530 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KCBGAEBN_01531 6.4e-116 manY G PTS system sorbose-specific iic component
KCBGAEBN_01532 6.1e-147 manN G system, mannose fructose sorbose family IID component
KCBGAEBN_01533 2.4e-52 manO S Domain of unknown function (DUF956)
KCBGAEBN_01534 9.5e-16 S Protein of unknown function (DUF805)
KCBGAEBN_01535 2.1e-70 mltD CBM50 M NlpC P60 family protein
KCBGAEBN_01536 4.7e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KCBGAEBN_01537 4.9e-165 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCBGAEBN_01538 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
KCBGAEBN_01539 3.5e-48 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KCBGAEBN_01540 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KCBGAEBN_01541 3.9e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCBGAEBN_01542 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCBGAEBN_01543 2e-46 S CRISPR-associated protein (Cas_Csn2)
KCBGAEBN_01544 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
KCBGAEBN_01548 3e-95 L Transposase IS66 family
KCBGAEBN_01549 8.1e-38 K transcriptional regulator PadR family
KCBGAEBN_01550 7.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
KCBGAEBN_01551 3.1e-16 S Putative adhesin
KCBGAEBN_01552 2.2e-16 pspC KT PspC domain
KCBGAEBN_01554 3e-13 S Enterocin A Immunity
KCBGAEBN_01555 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KCBGAEBN_01556 5.7e-261 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
KCBGAEBN_01557 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KCBGAEBN_01558 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KCBGAEBN_01559 1.5e-120 potB P ABC transporter permease
KCBGAEBN_01560 1.7e-103 potC U Binding-protein-dependent transport system inner membrane component
KCBGAEBN_01561 1.3e-159 potD P ABC transporter
KCBGAEBN_01562 7.8e-132 ABC-SBP S ABC transporter
KCBGAEBN_01563 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KCBGAEBN_01564 1.4e-107 XK27_08845 S ABC transporter, ATP-binding protein
KCBGAEBN_01565 1.5e-67 M ErfK YbiS YcfS YnhG
KCBGAEBN_01566 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KCBGAEBN_01567 1.9e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KCBGAEBN_01568 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KCBGAEBN_01569 1.2e-102 pgm3 G phosphoglycerate mutase
KCBGAEBN_01570 8.5e-58 S CAAX protease self-immunity
KCBGAEBN_01571 2e-45 C Flavodoxin
KCBGAEBN_01572 1.2e-57 yphH S Cupin domain
KCBGAEBN_01573 1e-45 yphJ 4.1.1.44 S decarboxylase
KCBGAEBN_01574 1.2e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
KCBGAEBN_01575 5.1e-108 metQ1 P Belongs to the nlpA lipoprotein family
KCBGAEBN_01576 2e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCBGAEBN_01577 1.3e-69 metI P ABC transporter permease
KCBGAEBN_01578 8.8e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KCBGAEBN_01579 3e-84 drgA C nitroreductase
KCBGAEBN_01580 1.1e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
KCBGAEBN_01581 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
KCBGAEBN_01582 5.3e-171 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KCBGAEBN_01583 1.7e-264 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KCBGAEBN_01585 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCBGAEBN_01586 2.4e-31 metI U ABC transporter permease
KCBGAEBN_01587 1.5e-128 metQ M Belongs to the nlpA lipoprotein family
KCBGAEBN_01588 6.5e-59 S Protein of unknown function (DUF4256)
KCBGAEBN_01591 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KCBGAEBN_01592 2.8e-166 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
KCBGAEBN_01593 1.5e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KCBGAEBN_01594 4e-230 lpdA 1.8.1.4 C Dehydrogenase
KCBGAEBN_01595 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
KCBGAEBN_01596 9.2e-56 S Protein of unknown function (DUF975)
KCBGAEBN_01597 2.2e-77 E GDSL-like Lipase/Acylhydrolase family
KCBGAEBN_01598 6.1e-39
KCBGAEBN_01599 4.1e-27 gcvR T Belongs to the UPF0237 family
KCBGAEBN_01600 2.1e-220 XK27_08635 S UPF0210 protein
KCBGAEBN_01601 4.5e-87 fruR K DeoR C terminal sensor domain
KCBGAEBN_01602 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KCBGAEBN_01603 5.1e-268 fruA 2.7.1.202 GT Phosphotransferase System
KCBGAEBN_01604 1.2e-49 cps3F
KCBGAEBN_01605 2.7e-83 S Membrane
KCBGAEBN_01606 1.8e-254 E Amino acid permease
KCBGAEBN_01607 5e-225 cadA P P-type ATPase
KCBGAEBN_01608 6.4e-114 degV S EDD domain protein, DegV family
KCBGAEBN_01609 1.9e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KCBGAEBN_01610 5.6e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
KCBGAEBN_01611 1.9e-27 ydiI Q Thioesterase superfamily
KCBGAEBN_01612 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KCBGAEBN_01613 5.6e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KCBGAEBN_01614 5.6e-82 S L,D-transpeptidase catalytic domain
KCBGAEBN_01615 4.4e-165 EGP Major facilitator Superfamily
KCBGAEBN_01616 1.1e-21 K helix_turn_helix multiple antibiotic resistance protein
KCBGAEBN_01617 6e-226 pipD E Dipeptidase
KCBGAEBN_01618 7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KCBGAEBN_01619 2.6e-32 ywjH S Protein of unknown function (DUF1634)
KCBGAEBN_01620 2.2e-119 yxaA S membrane transporter protein
KCBGAEBN_01621 7.6e-83 lysR5 K LysR substrate binding domain
KCBGAEBN_01622 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
KCBGAEBN_01623 9.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCBGAEBN_01624 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KCBGAEBN_01625 2.3e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
KCBGAEBN_01626 3.6e-242 lysP E amino acid
KCBGAEBN_01627 2.1e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KCBGAEBN_01628 1.6e-137 L Belongs to the 'phage' integrase family
KCBGAEBN_01641 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KCBGAEBN_01642 2.1e-185 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KCBGAEBN_01643 6.3e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KCBGAEBN_01644 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KCBGAEBN_01645 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KCBGAEBN_01647 1.6e-55 ctsR K Belongs to the CtsR family
KCBGAEBN_01648 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KCBGAEBN_01649 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCBGAEBN_01650 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCBGAEBN_01651 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
KCBGAEBN_01652 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KCBGAEBN_01653 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KCBGAEBN_01654 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCBGAEBN_01655 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KCBGAEBN_01656 5.2e-90 patB 4.4.1.8 E Aminotransferase, class I
KCBGAEBN_01657 2.5e-113 K response regulator
KCBGAEBN_01658 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
KCBGAEBN_01659 1.5e-91 lacX 5.1.3.3 G Aldose 1-epimerase
KCBGAEBN_01660 3.9e-146 G Transporter, major facilitator family protein
KCBGAEBN_01661 5.3e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KCBGAEBN_01662 2.8e-245 yhcA V ABC transporter, ATP-binding protein
KCBGAEBN_01663 3.4e-35 K Bacterial regulatory proteins, tetR family
KCBGAEBN_01664 7.6e-223 lmrA V ABC transporter, ATP-binding protein
KCBGAEBN_01665 1.8e-254 yfiC V ABC transporter
KCBGAEBN_01667 3.2e-45 yjcF K protein acetylation
KCBGAEBN_01668 3.5e-26 S Sel1-like repeats.
KCBGAEBN_01669 5.4e-55 L phosphatase homologous to the C-terminal domain of histone macroH2A1
KCBGAEBN_01670 3.3e-71 lemA S LemA family
KCBGAEBN_01671 1.3e-114 htpX O Belongs to the peptidase M48B family
KCBGAEBN_01673 2e-271 helD 3.6.4.12 L DNA helicase
KCBGAEBN_01674 4.1e-73 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCBGAEBN_01675 1.3e-32 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCBGAEBN_01676 6.7e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCBGAEBN_01677 1.6e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KCBGAEBN_01678 4.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
KCBGAEBN_01679 5.9e-104 ybhR V ABC transporter
KCBGAEBN_01680 7.9e-32 K Bacterial regulatory proteins, tetR family
KCBGAEBN_01681 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
KCBGAEBN_01682 3.3e-151 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KCBGAEBN_01683 3.9e-128
KCBGAEBN_01684 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCBGAEBN_01685 7.8e-103 tatD L hydrolase, TatD family
KCBGAEBN_01686 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KCBGAEBN_01687 1.4e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KCBGAEBN_01688 2.7e-22 veg S Biofilm formation stimulator VEG
KCBGAEBN_01689 3.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
KCBGAEBN_01690 5.5e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
KCBGAEBN_01691 8.2e-47 argR K Regulates arginine biosynthesis genes
KCBGAEBN_01692 4.8e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KCBGAEBN_01693 3.5e-156 amtB P ammonium transporter
KCBGAEBN_01695 1.7e-201 argH 4.3.2.1 E argininosuccinate lyase
KCBGAEBN_01696 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KCBGAEBN_01697 1.5e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KCBGAEBN_01698 9e-128 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCBGAEBN_01699 4.4e-101 pfoS S Phosphotransferase system, EIIC
KCBGAEBN_01700 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCBGAEBN_01701 6.6e-53 adhR K helix_turn_helix, mercury resistance
KCBGAEBN_01702 5.2e-137 purR 2.4.2.7 F pur operon repressor
KCBGAEBN_01703 1.9e-47 EGP Transmembrane secretion effector
KCBGAEBN_01704 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCBGAEBN_01705 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCBGAEBN_01706 3.1e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCBGAEBN_01707 3.1e-113 dkg S reductase
KCBGAEBN_01708 1.7e-24
KCBGAEBN_01709 6.7e-78 2.4.2.3 F Phosphorylase superfamily
KCBGAEBN_01710 1.4e-290 ybiT S ABC transporter, ATP-binding protein
KCBGAEBN_01711 2.1e-18 ytkL S Beta-lactamase superfamily domain
KCBGAEBN_01712 1.2e-34 ytkL S Belongs to the UPF0173 family
KCBGAEBN_01713 4.5e-100 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KCBGAEBN_01714 2.1e-125 S overlaps another CDS with the same product name
KCBGAEBN_01715 2.2e-86 S overlaps another CDS with the same product name
KCBGAEBN_01717 4.6e-57 spoVK O ATPase family associated with various cellular activities (AAA)
KCBGAEBN_01718 2.3e-22
KCBGAEBN_01719 2.7e-38 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
KCBGAEBN_01721 1.3e-63
KCBGAEBN_01722 8.2e-216 L Probable transposase
KCBGAEBN_01723 6e-60 ydcZ S Putative inner membrane exporter, YdcZ
KCBGAEBN_01724 6.4e-87 S hydrolase
KCBGAEBN_01725 2.5e-205 ywfO S HD domain protein
KCBGAEBN_01726 9.8e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
KCBGAEBN_01727 1.8e-32 ywiB S Domain of unknown function (DUF1934)
KCBGAEBN_01728 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KCBGAEBN_01729 1.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KCBGAEBN_01732 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCBGAEBN_01733 1.2e-188 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KCBGAEBN_01734 3.6e-41 rpmE2 J Ribosomal protein L31
KCBGAEBN_01735 2.8e-61
KCBGAEBN_01736 7.8e-255 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
KCBGAEBN_01738 4.7e-79 S Cell surface protein
KCBGAEBN_01740 1.6e-180 pbuG S permease
KCBGAEBN_01741 8.4e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
KCBGAEBN_01742 1.8e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KCBGAEBN_01743 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KCBGAEBN_01744 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KCBGAEBN_01745 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KCBGAEBN_01746 5.4e-13
KCBGAEBN_01747 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
KCBGAEBN_01748 2.5e-91 yunF F Protein of unknown function DUF72
KCBGAEBN_01749 2.3e-156 nrnB S DHHA1 domain
KCBGAEBN_01750 3.7e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KCBGAEBN_01751 2.2e-59
KCBGAEBN_01752 6e-49 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
KCBGAEBN_01753 5.4e-23 S Cytochrome B5
KCBGAEBN_01754 1.1e-19 sigH K DNA-templated transcription, initiation
KCBGAEBN_01755 2.9e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
KCBGAEBN_01756 3.2e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCBGAEBN_01757 2.6e-97 ygaC J Belongs to the UPF0374 family
KCBGAEBN_01758 6.9e-92 yueF S AI-2E family transporter
KCBGAEBN_01759 1.9e-157 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KCBGAEBN_01760 1.4e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KCBGAEBN_01761 4e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KCBGAEBN_01762 6.3e-36
KCBGAEBN_01763 0.0 lacL 3.2.1.23 G -beta-galactosidase
KCBGAEBN_01764 1.2e-288 lacS G Transporter
KCBGAEBN_01765 5.9e-111 galR K Transcriptional regulator
KCBGAEBN_01766 2.6e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KCBGAEBN_01767 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCBGAEBN_01768 1.2e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KCBGAEBN_01769 0.0 rafA 3.2.1.22 G alpha-galactosidase
KCBGAEBN_01770 5e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
KCBGAEBN_01771 3e-23 XK27_09445 S Domain of unknown function (DUF1827)
KCBGAEBN_01772 0.0 clpE O Belongs to the ClpA ClpB family
KCBGAEBN_01773 1.5e-15
KCBGAEBN_01774 9.7e-37 ptsH G phosphocarrier protein HPR
KCBGAEBN_01775 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCBGAEBN_01776 3.9e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KCBGAEBN_01777 1.2e-127 cpoA GT4 M Glycosyltransferase, group 1 family protein
KCBGAEBN_01778 1.5e-130 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCBGAEBN_01779 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
KCBGAEBN_01780 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)