ORF_ID e_value Gene_name EC_number CAZy COGs Description
HDDEELLK_00001 9e-30 yqkB S Belongs to the HesB IscA family
HDDEELLK_00002 6e-66 yxkH G Polysaccharide deacetylase
HDDEELLK_00003 1.8e-07
HDDEELLK_00004 3.8e-53 K LysR substrate binding domain
HDDEELLK_00005 1.5e-122 MA20_14895 S Conserved hypothetical protein 698
HDDEELLK_00006 1.1e-199 nupG F Nucleoside
HDDEELLK_00007 5.3e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDDEELLK_00008 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDDEELLK_00009 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HDDEELLK_00010 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDDEELLK_00011 6.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDDEELLK_00012 9e-20 yaaA S S4 domain protein YaaA
HDDEELLK_00013 8.4e-154 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDDEELLK_00014 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDDEELLK_00015 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDDEELLK_00016 6.2e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
HDDEELLK_00017 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDDEELLK_00018 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDDEELLK_00019 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HDDEELLK_00020 5.6e-117 S Glycosyl transferase family 2
HDDEELLK_00021 7.4e-64 D peptidase
HDDEELLK_00022 0.0 asnB 6.3.5.4 E Asparagine synthase
HDDEELLK_00023 3.7e-37 yiiE S Protein of unknown function (DUF1211)
HDDEELLK_00024 3.3e-12 yiiE S Protein of unknown function (DUF1211)
HDDEELLK_00025 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDDEELLK_00026 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDDEELLK_00027 3.6e-17 yneR
HDDEELLK_00028 1.5e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDDEELLK_00029 2.2e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
HDDEELLK_00030 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HDDEELLK_00031 1.1e-151 mdtG EGP Major facilitator Superfamily
HDDEELLK_00032 3.8e-14 yobS K transcriptional regulator
HDDEELLK_00033 2.8e-109 glcU U sugar transport
HDDEELLK_00034 4.4e-170 yjjP S Putative threonine/serine exporter
HDDEELLK_00035 2.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
HDDEELLK_00036 2.2e-96 yicL EG EamA-like transporter family
HDDEELLK_00037 1.8e-222 pepF E Oligopeptidase F
HDDEELLK_00038 6.5e-45 mccA 2.5.1.134, 2.5.1.47 E Pyridoxal-phosphate dependent enzyme
HDDEELLK_00039 4.4e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HDDEELLK_00040 1.1e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
HDDEELLK_00041 8.4e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HDDEELLK_00042 4e-23 relB L RelB antitoxin
HDDEELLK_00044 8.3e-172 S Putative peptidoglycan binding domain
HDDEELLK_00045 1.2e-31 K Transcriptional regulator, MarR family
HDDEELLK_00046 2e-215 XK27_09600 V ABC transporter, ATP-binding protein
HDDEELLK_00047 1.1e-229 V ABC transporter transmembrane region
HDDEELLK_00049 4.3e-96 S Domain of unknown function DUF87
HDDEELLK_00051 4.7e-106 yxeH S hydrolase
HDDEELLK_00052 1.8e-120 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HDDEELLK_00053 9e-114 K response regulator
HDDEELLK_00054 1.1e-272 vicK 2.7.13.3 T Histidine kinase
HDDEELLK_00055 2.7e-103 yycH S YycH protein
HDDEELLK_00056 3.6e-79 yycI S YycH protein
HDDEELLK_00057 5.1e-16 yyaQ S YjbR
HDDEELLK_00058 2.3e-110 vicX 3.1.26.11 S domain protein
HDDEELLK_00059 3.7e-145 htrA 3.4.21.107 O serine protease
HDDEELLK_00060 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDDEELLK_00061 7.2e-208 G glycerol-3-phosphate transporter
HDDEELLK_00062 8.3e-138 S interspecies interaction between organisms
HDDEELLK_00063 7.1e-66 secY2 U SecY translocase
HDDEELLK_00064 1.7e-77 asp1 S Accessory Sec system protein Asp1
HDDEELLK_00067 5.5e-149 mepA V MATE efflux family protein
HDDEELLK_00068 6e-152 lsa S ABC transporter
HDDEELLK_00069 4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDDEELLK_00070 1e-109 puuD S peptidase C26
HDDEELLK_00071 2.9e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HDDEELLK_00072 1.1e-25
HDDEELLK_00073 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HDDEELLK_00074 1.1e-59 uspA T Universal stress protein family
HDDEELLK_00076 1.1e-209 glnP P ABC transporter
HDDEELLK_00077 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HDDEELLK_00078 3.8e-93 yihY S Belongs to the UPF0761 family
HDDEELLK_00079 6.2e-12 mltD CBM50 M Lysin motif
HDDEELLK_00080 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDDEELLK_00081 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
HDDEELLK_00082 5.1e-54 fld C Flavodoxin
HDDEELLK_00083 8.7e-53 gtcA S Teichoic acid glycosylation protein
HDDEELLK_00084 0.0 S Bacterial membrane protein YfhO
HDDEELLK_00085 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HDDEELLK_00086 1.7e-122 S Sulfite exporter TauE/SafE
HDDEELLK_00087 2.4e-70 K Sugar-specific transcriptional regulator TrmB
HDDEELLK_00088 2.4e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDDEELLK_00089 3.5e-182 pepS E Thermophilic metalloprotease (M29)
HDDEELLK_00090 3e-266 E Amino acid permease
HDDEELLK_00091 4.9e-85 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HDDEELLK_00092 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HDDEELLK_00093 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
HDDEELLK_00094 4.3e-213 malT G Transporter, major facilitator family protein
HDDEELLK_00095 9.4e-101 malR K Transcriptional regulator, LacI family
HDDEELLK_00096 3.9e-279 kup P Transport of potassium into the cell
HDDEELLK_00098 1.5e-20 S Domain of unknown function (DUF3284)
HDDEELLK_00099 1.5e-159 yfmL L DEAD DEAH box helicase
HDDEELLK_00100 5.4e-128 mocA S Oxidoreductase
HDDEELLK_00101 3.4e-24 S Domain of unknown function (DUF4828)
HDDEELLK_00102 9.5e-176 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HDDEELLK_00103 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDDEELLK_00104 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HDDEELLK_00105 6.9e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HDDEELLK_00106 4.2e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HDDEELLK_00107 2.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDDEELLK_00108 1.4e-219 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HDDEELLK_00109 3.8e-42 O ADP-ribosylglycohydrolase
HDDEELLK_00110 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HDDEELLK_00111 2.2e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HDDEELLK_00112 1.3e-34 K GNAT family
HDDEELLK_00113 1.7e-40
HDDEELLK_00115 1.9e-176 mgtE P Acts as a magnesium transporter
HDDEELLK_00116 6.9e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HDDEELLK_00117 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDDEELLK_00118 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
HDDEELLK_00119 4.3e-257 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDDEELLK_00120 3.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HDDEELLK_00121 2.2e-193 pbuX F xanthine permease
HDDEELLK_00122 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDDEELLK_00123 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
HDDEELLK_00124 3.2e-64 S ECF transporter, substrate-specific component
HDDEELLK_00125 2.2e-126 mleP S Sodium Bile acid symporter family
HDDEELLK_00126 3.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HDDEELLK_00127 6.2e-72 mleR K LysR family
HDDEELLK_00128 1.1e-56 K transcriptional
HDDEELLK_00129 7.6e-41 K Bacterial regulatory proteins, tetR family
HDDEELLK_00130 6.1e-60 T Belongs to the universal stress protein A family
HDDEELLK_00131 1.2e-44 K Copper transport repressor CopY TcrY
HDDEELLK_00132 2.7e-10 fhaB M Rib/alpha-like repeat
HDDEELLK_00133 5.5e-11 fhaB M Rib/alpha-like repeat
HDDEELLK_00134 2.9e-96 ypuA S Protein of unknown function (DUF1002)
HDDEELLK_00135 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
HDDEELLK_00136 1.1e-161 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDDEELLK_00137 7.4e-18 yncA 2.3.1.79 S Maltose acetyltransferase
HDDEELLK_00138 6.9e-206 yflS P Sodium:sulfate symporter transmembrane region
HDDEELLK_00139 4.7e-199 frdC 1.3.5.4 C FAD binding domain
HDDEELLK_00140 1.5e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDDEELLK_00141 4.4e-14 ybaN S Protein of unknown function (DUF454)
HDDEELLK_00142 4e-179 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HDDEELLK_00143 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDDEELLK_00144 1.1e-95 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDDEELLK_00145 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HDDEELLK_00146 1.5e-71 ywlG S Belongs to the UPF0340 family
HDDEELLK_00147 4.4e-52 S Acetyltransferase (GNAT) domain
HDDEELLK_00148 1.7e-25 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HDDEELLK_00149 9.4e-34 yjaB_1 K Acetyltransferase (GNAT) domain
HDDEELLK_00150 4.5e-15 Z012_01675 S X-Pro dipeptidyl-peptidase (S15 family)
HDDEELLK_00151 7.9e-50 K Cro/C1-type HTH DNA-binding domain
HDDEELLK_00152 1e-173 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
HDDEELLK_00153 7.1e-43
HDDEELLK_00154 1.7e-97
HDDEELLK_00155 8.8e-17 aguA_2 3.5.3.12 E Belongs to the agmatine deiminase family
HDDEELLK_00156 7.9e-50 K Cro/C1-type HTH DNA-binding domain
HDDEELLK_00157 7.7e-72 S Beta-lactamase superfamily domain
HDDEELLK_00159 8.1e-17
HDDEELLK_00160 1.3e-119 L Mrr N-terminal domain
HDDEELLK_00161 1.5e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDDEELLK_00162 3.4e-146 yegS 2.7.1.107 G Lipid kinase
HDDEELLK_00163 4.3e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDDEELLK_00164 1.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDDEELLK_00165 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDDEELLK_00166 7.1e-161 camS S sex pheromone
HDDEELLK_00167 4.3e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDDEELLK_00168 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HDDEELLK_00169 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HDDEELLK_00172 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HDDEELLK_00173 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDDEELLK_00174 1.1e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDDEELLK_00175 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDDEELLK_00176 1.9e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDDEELLK_00177 8e-95 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDDEELLK_00178 2.3e-41 yabR J RNA binding
HDDEELLK_00179 1e-21 divIC D Septum formation initiator
HDDEELLK_00180 3.1e-30 yabO J S4 domain protein
HDDEELLK_00181 2.1e-139 yabM S Polysaccharide biosynthesis protein
HDDEELLK_00182 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDDEELLK_00183 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDDEELLK_00184 8.1e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDDEELLK_00185 5.5e-86 S (CBS) domain
HDDEELLK_00186 3.1e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDDEELLK_00187 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDDEELLK_00188 7.2e-53 perR P Belongs to the Fur family
HDDEELLK_00189 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
HDDEELLK_00190 2.7e-98 sbcC L Putative exonuclease SbcCD, C subunit
HDDEELLK_00191 5.7e-115 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDDEELLK_00192 5.5e-45 M LysM domain protein
HDDEELLK_00193 5.6e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDDEELLK_00194 8.2e-86 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HDDEELLK_00195 3e-34 ygfC K Bacterial regulatory proteins, tetR family
HDDEELLK_00196 4.5e-101 hrtB V ABC transporter permease
HDDEELLK_00197 2e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HDDEELLK_00198 1e-67 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HDDEELLK_00199 0.0 helD 3.6.4.12 L DNA helicase
HDDEELLK_00200 8.9e-246 yjbQ P TrkA C-terminal domain protein
HDDEELLK_00201 6.1e-31
HDDEELLK_00202 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
HDDEELLK_00203 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDDEELLK_00204 9.4e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDDEELLK_00205 2.2e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDDEELLK_00206 5.2e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDDEELLK_00207 2.3e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDDEELLK_00208 4.8e-53 rplQ J Ribosomal protein L17
HDDEELLK_00209 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDDEELLK_00210 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDDEELLK_00211 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDDEELLK_00212 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HDDEELLK_00213 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDDEELLK_00214 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDDEELLK_00215 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDDEELLK_00216 1e-67 rplO J Binds to the 23S rRNA
HDDEELLK_00217 2.1e-22 rpmD J Ribosomal protein L30
HDDEELLK_00218 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDDEELLK_00219 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDDEELLK_00220 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDDEELLK_00221 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDDEELLK_00222 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDDEELLK_00223 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDDEELLK_00224 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDDEELLK_00225 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDDEELLK_00226 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDDEELLK_00227 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HDDEELLK_00228 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDDEELLK_00229 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDDEELLK_00230 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDDEELLK_00231 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDDEELLK_00232 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDDEELLK_00233 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDDEELLK_00234 1e-100 rplD J Forms part of the polypeptide exit tunnel
HDDEELLK_00235 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDDEELLK_00236 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HDDEELLK_00237 6.2e-166 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDDEELLK_00238 6.5e-79 K rpiR family
HDDEELLK_00239 1.4e-52 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HDDEELLK_00240 8.5e-147 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HDDEELLK_00241 6.5e-21 K Acetyltransferase (GNAT) domain
HDDEELLK_00242 6.4e-182 steT E amino acid
HDDEELLK_00243 2.9e-82 glnP P ABC transporter permease
HDDEELLK_00244 1.2e-85 gluC P ABC transporter permease
HDDEELLK_00245 1.9e-99 glnH ET ABC transporter
HDDEELLK_00246 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDDEELLK_00247 1.4e-14
HDDEELLK_00248 5e-98
HDDEELLK_00250 3.2e-53 zur P Belongs to the Fur family
HDDEELLK_00251 3.7e-212 yfnA E Amino Acid
HDDEELLK_00252 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDDEELLK_00253 0.0 L Helicase C-terminal domain protein
HDDEELLK_00254 2e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
HDDEELLK_00255 2.1e-180 yhdP S Transporter associated domain
HDDEELLK_00256 1.4e-25
HDDEELLK_00257 2.4e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDDEELLK_00258 9.6e-132 bacI V MacB-like periplasmic core domain
HDDEELLK_00259 9.6e-97 V ABC transporter
HDDEELLK_00260 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDDEELLK_00261 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
HDDEELLK_00262 3.6e-140 V MatE
HDDEELLK_00263 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDDEELLK_00264 5e-87 S Alpha beta hydrolase
HDDEELLK_00265 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDDEELLK_00266 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDDEELLK_00267 4.6e-112 argE 3.5.1.18 E Peptidase dimerisation domain
HDDEELLK_00268 3.2e-101 IQ Enoyl-(Acyl carrier protein) reductase
HDDEELLK_00269 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
HDDEELLK_00270 9.6e-54 queT S QueT transporter
HDDEELLK_00272 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
HDDEELLK_00273 1.1e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDDEELLK_00274 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDDEELLK_00275 5.5e-34 trxA O Belongs to the thioredoxin family
HDDEELLK_00276 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
HDDEELLK_00277 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDDEELLK_00278 1.3e-49 S Threonine/Serine exporter, ThrE
HDDEELLK_00279 4.3e-82 thrE S Putative threonine/serine exporter
HDDEELLK_00280 3.1e-27 cspC K Cold shock protein
HDDEELLK_00281 3.1e-89 sirR K Helix-turn-helix diphteria tox regulatory element
HDDEELLK_00282 2.4e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HDDEELLK_00283 1.2e-22
HDDEELLK_00284 1.2e-58 3.6.1.27 I phosphatase
HDDEELLK_00285 3.1e-25
HDDEELLK_00286 2.1e-66 I alpha/beta hydrolase fold
HDDEELLK_00287 1.3e-38 azlD S branched-chain amino acid
HDDEELLK_00288 1.1e-104 azlC E AzlC protein
HDDEELLK_00289 2e-17
HDDEELLK_00290 2.2e-119 xth 3.1.11.2 L exodeoxyribonuclease III
HDDEELLK_00291 5.8e-100 V domain protein
HDDEELLK_00292 7.2e-18
HDDEELLK_00296 1e-11 S zinc-ribbon domain
HDDEELLK_00298 1.8e-11 S Mor transcription activator family
HDDEELLK_00299 7.8e-60 yfjR K WYL domain
HDDEELLK_00300 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDDEELLK_00301 3.8e-173 malY 4.4.1.8 E Aminotransferase, class I
HDDEELLK_00302 3.1e-118 K AI-2E family transporter
HDDEELLK_00303 1.8e-61 EG EamA-like transporter family
HDDEELLK_00304 1.8e-76 L haloacid dehalogenase-like hydrolase
HDDEELLK_00305 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HDDEELLK_00306 1.7e-67 1.5.1.38 S NADPH-dependent FMN reductase
HDDEELLK_00307 2.9e-164 C Luciferase-like monooxygenase
HDDEELLK_00308 3.6e-41 K Transcriptional regulator, HxlR family
HDDEELLK_00309 2.3e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDDEELLK_00310 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
HDDEELLK_00311 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HDDEELLK_00312 9.2e-82 pncA Q isochorismatase
HDDEELLK_00313 4.6e-63 3.1.3.73 G phosphoglycerate mutase
HDDEELLK_00314 7.3e-259 treB G phosphotransferase system
HDDEELLK_00315 3.4e-84 treR K UTRA
HDDEELLK_00316 8.2e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HDDEELLK_00317 8.4e-168 mdtG EGP Major facilitator Superfamily
HDDEELLK_00319 8.2e-57 S peptidoglycan catabolic process
HDDEELLK_00320 5.2e-13 ganB 3.2.1.89 G arabinogalactan
HDDEELLK_00321 1.6e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDDEELLK_00322 8.8e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HDDEELLK_00323 4e-128 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDDEELLK_00324 8.3e-178 thrC 4.2.3.1 E Threonine synthase
HDDEELLK_00325 5.3e-78 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HDDEELLK_00326 1.4e-22 ganB 3.2.1.89 G arabinogalactan
HDDEELLK_00327 2.6e-60 S Psort location CytoplasmicMembrane, score
HDDEELLK_00328 1.6e-164 XK27_08315 M Sulfatase
HDDEELLK_00329 2.8e-80 S Bacterial membrane protein YfhO
HDDEELLK_00330 1.3e-10 S Bacterial membrane protein YfhO
HDDEELLK_00331 1.6e-16 S Bacterial membrane protein YfhO
HDDEELLK_00332 3.6e-14
HDDEELLK_00333 2.4e-54 cps3I G Acyltransferase family
HDDEELLK_00334 4.2e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HDDEELLK_00335 1.2e-39 2.7.7.65 T phosphorelay sensor kinase activity
HDDEELLK_00336 1.1e-157 XK27_09615 S reductase
HDDEELLK_00337 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
HDDEELLK_00338 1.1e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDDEELLK_00339 9.5e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDDEELLK_00340 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDDEELLK_00341 3.8e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HDDEELLK_00342 1.7e-133 coaA 2.7.1.33 F Pantothenic acid kinase
HDDEELLK_00343 4.1e-43 E lipolytic protein G-D-S-L family
HDDEELLK_00344 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDDEELLK_00345 5.6e-190 glnPH2 P ABC transporter permease
HDDEELLK_00346 9.4e-214 yjeM E Amino Acid
HDDEELLK_00347 2e-137 tetA EGP Major facilitator Superfamily
HDDEELLK_00349 6.2e-70 rny D Peptidase family M23
HDDEELLK_00350 7.7e-189 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HDDEELLK_00351 2.8e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
HDDEELLK_00352 9.1e-112 S Psort location CytoplasmicMembrane, score
HDDEELLK_00353 2.8e-95 waaB GT4 M Glycosyl transferases group 1
HDDEELLK_00354 1.3e-109 M Core-2/I-Branching enzyme
HDDEELLK_00355 1.1e-93 M transferase activity, transferring glycosyl groups
HDDEELLK_00356 8.1e-67 cps3F
HDDEELLK_00357 9.1e-92 rfbP M Bacterial sugar transferase
HDDEELLK_00358 1.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDDEELLK_00359 1.6e-111 ywqE 3.1.3.48 GM PHP domain protein
HDDEELLK_00360 2.7e-81 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HDDEELLK_00361 2.6e-77 epsB M biosynthesis protein
HDDEELLK_00362 3.8e-215 ugd 1.1.1.22 M UDP binding domain
HDDEELLK_00364 1.3e-45 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HDDEELLK_00365 1.2e-20 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HDDEELLK_00366 2.2e-90 tuaB S Polysaccharide biosynthesis protein
HDDEELLK_00367 1e-66 ppm1 GT2 M Glycosyl transferase family 2
HDDEELLK_00368 5.1e-15 wzy S EpsG family
HDDEELLK_00369 1.1e-31 M Glycosyl transferases group 1
HDDEELLK_00370 3.1e-19 2.3.1.18 S Psort location Cytoplasmic, score 9.26
HDDEELLK_00371 3.3e-99 S Glycosyltransferase WbsX
HDDEELLK_00372 5e-43 cps M Glycosyltransferase family 92
HDDEELLK_00373 2.2e-67 rgpB M Glycosyl transferase family 2
HDDEELLK_00374 2e-142 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDDEELLK_00375 1.7e-84 wbbL S Glycosyl transferase family 2
HDDEELLK_00376 2.8e-71 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
HDDEELLK_00377 1.1e-26 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
HDDEELLK_00378 3.4e-128 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDDEELLK_00379 5.6e-165 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDDEELLK_00380 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HDDEELLK_00381 4.2e-145 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HDDEELLK_00382 1.7e-72 S Glycosyltransferase like family 2
HDDEELLK_00383 4.5e-84 S Psort location CytoplasmicMembrane, score
HDDEELLK_00384 5.4e-99 waaB GT4 M Glycosyl transferases group 1
HDDEELLK_00385 4.6e-89 S Psort location CytoplasmicMembrane, score
HDDEELLK_00386 1.1e-61 S Glycosyltransferase like family 2
HDDEELLK_00387 4.9e-116 cps1D M Domain of unknown function (DUF4422)
HDDEELLK_00388 3e-39 S CAAX protease self-immunity
HDDEELLK_00389 9.1e-89 yvyE 3.4.13.9 S YigZ family
HDDEELLK_00390 2.9e-58 S Haloacid dehalogenase-like hydrolase
HDDEELLK_00391 2.9e-153 EGP Major facilitator Superfamily
HDDEELLK_00393 9e-68 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDDEELLK_00394 1.2e-27 yraB K transcriptional regulator
HDDEELLK_00395 9.8e-90 S NADPH-dependent FMN reductase
HDDEELLK_00396 2.3e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HDDEELLK_00397 1.5e-55 S ECF transporter, substrate-specific component
HDDEELLK_00398 2.5e-96 znuB U ABC 3 transport family
HDDEELLK_00399 1e-98 fhuC P ABC transporter
HDDEELLK_00400 1.3e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
HDDEELLK_00401 2e-38
HDDEELLK_00402 1.4e-53 XK27_01040 S Protein of unknown function (DUF1129)
HDDEELLK_00403 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDDEELLK_00404 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
HDDEELLK_00405 6.3e-109 spo0J K Belongs to the ParB family
HDDEELLK_00406 6.5e-118 soj D Sporulation initiation inhibitor
HDDEELLK_00407 1.7e-82 noc K Belongs to the ParB family
HDDEELLK_00408 6.2e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HDDEELLK_00409 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HDDEELLK_00410 1.4e-109 3.1.4.46 C phosphodiesterase
HDDEELLK_00411 0.0 pacL 3.6.3.8 P P-type ATPase
HDDEELLK_00412 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
HDDEELLK_00413 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HDDEELLK_00415 8e-64 srtA 3.4.22.70 M sortase family
HDDEELLK_00416 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HDDEELLK_00417 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HDDEELLK_00418 1.1e-33
HDDEELLK_00419 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDDEELLK_00420 1e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDDEELLK_00421 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDDEELLK_00422 3.6e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDDEELLK_00423 1.1e-39 ybjQ S Belongs to the UPF0145 family
HDDEELLK_00424 2.5e-08
HDDEELLK_00425 6.1e-96 V ABC transporter, ATP-binding protein
HDDEELLK_00426 1.1e-41 gntR1 K Transcriptional regulator, GntR family
HDDEELLK_00427 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HDDEELLK_00428 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDEELLK_00429 1.1e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HDDEELLK_00430 1.7e-107 terC P Integral membrane protein TerC family
HDDEELLK_00431 5.5e-39 K Transcriptional regulator
HDDEELLK_00432 5.7e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HDDEELLK_00433 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDDEELLK_00434 4.5e-102 tcyB E ABC transporter
HDDEELLK_00436 5e-37 M Glycosyl hydrolases family 25
HDDEELLK_00437 6.1e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDDEELLK_00438 5.9e-303 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDDEELLK_00439 1.4e-210 mtlR K Mga helix-turn-helix domain
HDDEELLK_00440 2.4e-175 yjcE P Sodium proton antiporter
HDDEELLK_00441 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDDEELLK_00442 3.1e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
HDDEELLK_00443 1.6e-68 dhaL 2.7.1.121 S Dak2
HDDEELLK_00444 7.6e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HDDEELLK_00445 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HDDEELLK_00446 1.7e-61 K Bacterial regulatory proteins, tetR family
HDDEELLK_00447 8.5e-209 brnQ U Component of the transport system for branched-chain amino acids
HDDEELLK_00449 1.1e-110 endA F DNA RNA non-specific endonuclease
HDDEELLK_00450 4.1e-75 XK27_02070 S Nitroreductase family
HDDEELLK_00451 2.4e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HDDEELLK_00452 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HDDEELLK_00453 4.7e-294 lai 4.2.1.53 S Myosin-crossreactive antigen
HDDEELLK_00454 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HDDEELLK_00455 9.3e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HDDEELLK_00456 5.1e-77 azlC E branched-chain amino acid
HDDEELLK_00457 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
HDDEELLK_00458 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
HDDEELLK_00459 2.1e-55 jag S R3H domain protein
HDDEELLK_00460 5.3e-54 K Transcriptional regulator C-terminal region
HDDEELLK_00461 5.9e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
HDDEELLK_00462 8.1e-287 pepO 3.4.24.71 O Peptidase family M13
HDDEELLK_00463 2.2e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
HDDEELLK_00464 2.1e-07 S SdpI/YhfL protein family
HDDEELLK_00465 7.8e-72 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HDDEELLK_00466 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
HDDEELLK_00467 5.1e-42 wecD K Acetyltransferase GNAT Family
HDDEELLK_00469 5e-255 XK27_06780 V ABC transporter permease
HDDEELLK_00470 6.4e-96 XK27_06785 V ABC transporter, ATP-binding protein
HDDEELLK_00471 2.4e-32 tetR K transcriptional regulator
HDDEELLK_00473 1.5e-34 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDDEELLK_00474 8.3e-60 L Probable transposase
HDDEELLK_00475 1.1e-25 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDDEELLK_00476 2.4e-121 ytbE S reductase
HDDEELLK_00477 9.3e-43 ytcD K HxlR-like helix-turn-helix
HDDEELLK_00478 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
HDDEELLK_00479 2e-67 ybbL S ABC transporter
HDDEELLK_00480 6.2e-163 oxlT P Major Facilitator Superfamily
HDDEELLK_00481 1.1e-52 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDDEELLK_00482 9.2e-47 S Short repeat of unknown function (DUF308)
HDDEELLK_00483 1.4e-30 tetR K Transcriptional regulator C-terminal region
HDDEELLK_00484 1.2e-150 yfeX P Peroxidase
HDDEELLK_00485 2.5e-16 S Protein of unknown function (DUF3021)
HDDEELLK_00486 4.5e-39 K LytTr DNA-binding domain
HDDEELLK_00487 1.1e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HDDEELLK_00488 1.7e-209 mmuP E amino acid
HDDEELLK_00489 5.4e-16 psiE S Phosphate-starvation-inducible E
HDDEELLK_00490 3.7e-155 oppF P Belongs to the ABC transporter superfamily
HDDEELLK_00491 1.3e-180 oppD P Belongs to the ABC transporter superfamily
HDDEELLK_00492 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDDEELLK_00493 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDDEELLK_00494 4e-202 oppA E ABC transporter, substratebinding protein
HDDEELLK_00495 1.6e-218 yifK E Amino acid permease
HDDEELLK_00496 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDDEELLK_00497 1.5e-56 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HDDEELLK_00498 5e-66 pgm3 G phosphoglycerate mutase family
HDDEELLK_00499 1.2e-250 ctpA 3.6.3.54 P P-type ATPase
HDDEELLK_00500 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HDDEELLK_00501 2.6e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HDDEELLK_00502 3.7e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HDDEELLK_00503 1.8e-181 EG GntP family permease
HDDEELLK_00504 5e-116 KT Putative sugar diacid recognition
HDDEELLK_00505 3.1e-22 K transcriptional regulator
HDDEELLK_00506 6.1e-75 hchA S intracellular protease amidase
HDDEELLK_00507 6.2e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HDDEELLK_00508 3.7e-113 lacI3 K helix_turn _helix lactose operon repressor
HDDEELLK_00509 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
HDDEELLK_00510 7.5e-39 2.7.1.191 G PTS system fructose IIA component
HDDEELLK_00511 3.2e-123 G PTS system mannose/fructose/sorbose family IID component
HDDEELLK_00512 4.4e-101 G PTS system sorbose-specific iic component
HDDEELLK_00513 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
HDDEELLK_00514 8.7e-81 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HDDEELLK_00515 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDDEELLK_00516 2.6e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
HDDEELLK_00517 1.1e-116 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
HDDEELLK_00518 6.9e-198 1.3.5.4 C FMN_bind
HDDEELLK_00519 2.2e-56 3.1.3.48 K Transcriptional regulator
HDDEELLK_00520 2.2e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HDDEELLK_00521 3.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HDDEELLK_00522 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HDDEELLK_00523 1.6e-128 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
HDDEELLK_00524 4.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HDDEELLK_00525 1.6e-81 S Belongs to the UPF0246 family
HDDEELLK_00526 7.9e-12 V CAAX protease self-immunity
HDDEELLK_00527 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
HDDEELLK_00528 3.9e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDDEELLK_00530 7.4e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDDEELLK_00531 4e-64 C FMN binding
HDDEELLK_00532 1.2e-205 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HDDEELLK_00533 1.7e-54 rplI J Binds to the 23S rRNA
HDDEELLK_00534 4.4e-262 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HDDEELLK_00535 1.4e-06
HDDEELLK_00539 8.8e-50 yugI 5.3.1.9 J general stress protein
HDDEELLK_00540 3.8e-97 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HDDEELLK_00541 3e-92 dedA S SNARE associated Golgi protein
HDDEELLK_00542 6e-32 S Protein of unknown function (DUF1461)
HDDEELLK_00543 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDDEELLK_00544 1.9e-53 yutD S Protein of unknown function (DUF1027)
HDDEELLK_00545 3e-57 S Calcineurin-like phosphoesterase
HDDEELLK_00546 9.3e-184 cycA E Amino acid permease
HDDEELLK_00547 5.8e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
HDDEELLK_00549 9.4e-11 S Putative Competence protein ComGF
HDDEELLK_00551 1.1e-13
HDDEELLK_00552 3.6e-27 comGC U competence protein ComGC
HDDEELLK_00553 1.3e-97 comGB NU type II secretion system
HDDEELLK_00554 1.1e-120 comGA NU Type II IV secretion system protein
HDDEELLK_00555 1.8e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDDEELLK_00556 1.5e-119 yebC K Transcriptional regulatory protein
HDDEELLK_00557 3.7e-42 S VanZ like family
HDDEELLK_00558 3.4e-159 ccpA K catabolite control protein A
HDDEELLK_00559 7.8e-173 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HDDEELLK_00560 3e-14
HDDEELLK_00563 4.5e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDDEELLK_00564 6.9e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDDEELLK_00565 2.3e-65 hly S protein, hemolysin III
HDDEELLK_00566 1.6e-40 M1-874 K Domain of unknown function (DUF1836)
HDDEELLK_00567 9.4e-84 S membrane
HDDEELLK_00568 1.1e-79 S VIT family
HDDEELLK_00569 5.2e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HDDEELLK_00570 2.7e-56 P Plays a role in the regulation of phosphate uptake
HDDEELLK_00571 6.1e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDDEELLK_00572 1e-113 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDDEELLK_00573 5.1e-122 pstA P Phosphate transport system permease protein PstA
HDDEELLK_00574 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
HDDEELLK_00575 1.1e-97 pstS P Phosphate
HDDEELLK_00576 1.3e-41 yjbH Q Thioredoxin
HDDEELLK_00577 2.5e-232 pepF E oligoendopeptidase F
HDDEELLK_00578 9.5e-68 coiA 3.6.4.12 S Competence protein
HDDEELLK_00579 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDDEELLK_00580 6.3e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HDDEELLK_00586 5.1e-08
HDDEELLK_00591 1.7e-60 K DeoR C terminal sensor domain
HDDEELLK_00592 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HDDEELLK_00593 8.3e-13 S Fic/DOC family
HDDEELLK_00594 9.9e-10 S Fic/DOC family
HDDEELLK_00595 8.7e-21 S Fic/DOC family
HDDEELLK_00596 1.6e-77 S Fic/DOC family
HDDEELLK_00597 5.6e-181 L PLD-like domain
HDDEELLK_00600 1.6e-108 L Initiator Replication protein
HDDEELLK_00601 6.6e-38 S Replication initiator protein A (RepA) N-terminus
HDDEELLK_00602 6.5e-149 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDDEELLK_00603 4.2e-45 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDDEELLK_00604 2.3e-218 L Probable transposase
HDDEELLK_00605 1.2e-27 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDDEELLK_00606 2.9e-14 bglG K CAT RNA binding domain
HDDEELLK_00607 9.6e-08 arbG1 K antiterminator
HDDEELLK_00608 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
HDDEELLK_00610 4.2e-35
HDDEELLK_00611 0.0 pepN 3.4.11.2 E aminopeptidase
HDDEELLK_00612 1.2e-44 2.7.13.3 T protein histidine kinase activity
HDDEELLK_00613 3e-35 agrA KT Response regulator of the LytR AlgR family
HDDEELLK_00614 6.3e-20 M domain protein
HDDEELLK_00615 3.9e-147 scrR K helix_turn _helix lactose operon repressor
HDDEELLK_00616 1.1e-217 scrB 3.2.1.26 GH32 G invertase
HDDEELLK_00617 3.1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
HDDEELLK_00618 1.2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HDDEELLK_00620 6.1e-125 yvgN C Aldo keto reductase
HDDEELLK_00621 1.1e-69 K DeoR C terminal sensor domain
HDDEELLK_00622 1.1e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDDEELLK_00623 6.9e-42 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HDDEELLK_00624 1.2e-216 pts36C G PTS system sugar-specific permease component
HDDEELLK_00626 5.1e-104 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
HDDEELLK_00628 4.7e-54 S COG NOG19168 non supervised orthologous group
HDDEELLK_00629 1.3e-180 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HDDEELLK_00630 4.9e-50 S Membrane
HDDEELLK_00631 3.1e-75 rhaR K helix_turn_helix, arabinose operon control protein
HDDEELLK_00632 1.5e-188 iolF EGP Major facilitator Superfamily
HDDEELLK_00633 2.6e-216 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HDDEELLK_00634 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HDDEELLK_00635 4.8e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HDDEELLK_00636 1.3e-108 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HDDEELLK_00638 1.2e-191 XK27_11280 S Psort location CytoplasmicMembrane, score
HDDEELLK_00640 2.4e-106 L Belongs to the 'phage' integrase family
HDDEELLK_00641 1.3e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
HDDEELLK_00642 6e-61 hsdM 2.1.1.72 V HsdM N-terminal domain
HDDEELLK_00644 3.2e-161 L T/G mismatch-specific endonuclease activity
HDDEELLK_00645 1.5e-62
HDDEELLK_00646 7.9e-66
HDDEELLK_00647 3e-57 yeeA V Type II restriction enzyme, methylase subunits
HDDEELLK_00648 1.2e-15 yeeA V Type II restriction enzyme, methylase subunits
HDDEELLK_00649 6e-216 yeeA V Type II restriction enzyme, methylase subunits
HDDEELLK_00650 1.4e-257 yeeB L DEAD-like helicases superfamily
HDDEELLK_00651 2.7e-94 pstS P T5orf172
HDDEELLK_00652 3.5e-19
HDDEELLK_00655 3.5e-133 potE2 E amino acid
HDDEELLK_00656 4.3e-147 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HDDEELLK_00657 5.2e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HDDEELLK_00658 5.6e-57 racA K Domain of unknown function (DUF1836)
HDDEELLK_00659 2e-80 yitS S EDD domain protein, DegV family
HDDEELLK_00660 4.2e-45 yjaB_1 K Acetyltransferase (GNAT) domain
HDDEELLK_00662 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDDEELLK_00663 0.0 O Belongs to the peptidase S8 family
HDDEELLK_00668 6.3e-54 1.14.12.17 C Oxidoreductase NAD-binding domain
HDDEELLK_00669 1.6e-55 tlpA2 L Transposase IS200 like
HDDEELLK_00670 1.7e-158 L transposase, IS605 OrfB family
HDDEELLK_00671 3.2e-85 dps P Ferritin-like domain
HDDEELLK_00672 1.5e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HDDEELLK_00673 7.5e-44 L hmm pf00665
HDDEELLK_00674 4.8e-32 P Heavy-metal-associated domain
HDDEELLK_00675 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HDDEELLK_00677 7e-70 L Integrase core domain
HDDEELLK_00678 2.6e-129 EGP Major Facilitator Superfamily
HDDEELLK_00679 8.2e-99 EGP Major Facilitator Superfamily
HDDEELLK_00680 1.7e-72 K Transcriptional regulator, LysR family
HDDEELLK_00681 3.6e-138 G Xylose isomerase-like TIM barrel
HDDEELLK_00682 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
HDDEELLK_00683 4.7e-217 1.3.5.4 C FAD binding domain
HDDEELLK_00684 1.4e-137 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDDEELLK_00685 2.9e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDDEELLK_00686 1.4e-142 xerS L Phage integrase family
HDDEELLK_00687 2e-10
HDDEELLK_00688 1.8e-36
HDDEELLK_00690 3.7e-14 S YjcQ protein
HDDEELLK_00693 2.1e-105 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HDDEELLK_00694 1.3e-71 ptp3 3.1.3.48 T Tyrosine phosphatase family
HDDEELLK_00695 4.4e-77 desR K helix_turn_helix, Lux Regulon
HDDEELLK_00696 1.9e-57 salK 2.7.13.3 T Histidine kinase
HDDEELLK_00697 1.6e-52 yvfS V ABC-2 type transporter
HDDEELLK_00698 1.2e-80 yvfR V ABC transporter
HDDEELLK_00699 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDDEELLK_00700 2.9e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HDDEELLK_00701 1.9e-29
HDDEELLK_00702 1.4e-60 sip L Belongs to the 'phage' integrase family
HDDEELLK_00703 5e-07
HDDEELLK_00706 1.5e-29 M CHAP domain
HDDEELLK_00708 3.8e-191 U type IV secretory pathway VirB4
HDDEELLK_00709 3.5e-27
HDDEELLK_00711 3.4e-77
HDDEELLK_00712 2e-220 U TraM recognition site of TraD and TraG
HDDEELLK_00716 2.9e-148 clpB O Belongs to the ClpA ClpB family
HDDEELLK_00719 3.2e-165 topA2 5.99.1.2 G Topoisomerase IA
HDDEELLK_00720 6.1e-43 L Protein of unknown function (DUF3991)
HDDEELLK_00721 4.5e-69
HDDEELLK_00724 4.7e-89 pac DM Glucan-binding protein C
HDDEELLK_00726 2.4e-106 L Belongs to the 'phage' integrase family
HDDEELLK_00727 5.7e-08
HDDEELLK_00728 8.6e-25 D nuclear chromosome segregation
HDDEELLK_00730 7.5e-239 bcgIB 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
HDDEELLK_00731 2.6e-76 S Fic/DOC family
HDDEELLK_00732 7.9e-11
HDDEELLK_00734 2.1e-62 ruvB 3.6.4.12 L four-way junction helicase activity
HDDEELLK_00738 3.8e-12 polC 2.7.7.7 L BRCA1 C Terminus (BRCT) domain
HDDEELLK_00739 7.5e-20
HDDEELLK_00742 6.1e-07
HDDEELLK_00747 5.8e-21 S Replication initiator protein A (RepA) N-terminus
HDDEELLK_00754 1.8e-16 3.4.21.88 K Peptidase S24-like
HDDEELLK_00756 1.5e-10 3.4.21.88 K Peptidase S24-like
HDDEELLK_00758 3.7e-162 3.1.21.3 L N-6 DNA Methylase
HDDEELLK_00760 6.3e-65 L ISXO2-like transposase domain
HDDEELLK_00761 7.8e-87 S Fic/DOC family
HDDEELLK_00763 4.6e-15 fhaB M Membrane
HDDEELLK_00764 2.5e-39
HDDEELLK_00766 1e-111 rssA S Phospholipase, patatin family
HDDEELLK_00767 4.4e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDDEELLK_00768 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HDDEELLK_00769 5.6e-45 S VIT family
HDDEELLK_00770 1.2e-239 sufB O assembly protein SufB
HDDEELLK_00771 1.4e-40 nifU C SUF system FeS assembly protein, NifU family
HDDEELLK_00772 1.8e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDDEELLK_00773 4.6e-145 sufD O FeS assembly protein SufD
HDDEELLK_00774 3.1e-115 sufC O FeS assembly ATPase SufC
HDDEELLK_00775 2e-225 E ABC transporter, substratebinding protein
HDDEELLK_00776 8.5e-138 yfeO P Voltage gated chloride channel
HDDEELLK_00777 3.2e-27 K Helix-turn-helix XRE-family like proteins
HDDEELLK_00778 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HDDEELLK_00779 6.6e-54
HDDEELLK_00781 3.6e-30 3.1.21.3 V Type I restriction modification DNA specificity domain
HDDEELLK_00782 3.2e-43 3.1.21.3 V type i restriction
HDDEELLK_00783 9.7e-127 xerC L Belongs to the 'phage' integrase family
HDDEELLK_00784 4.6e-59 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HDDEELLK_00785 4.1e-249 2.1.1.72 V type I restriction-modification system
HDDEELLK_00786 1.2e-56 hsdM 2.1.1.72 V HsdM N-terminal domain
HDDEELLK_00787 2.9e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
HDDEELLK_00788 2.5e-136 pfoS S Phosphotransferase system, EIIC
HDDEELLK_00789 9.3e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HDDEELLK_00790 1.3e-64 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HDDEELLK_00791 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HDDEELLK_00792 1.2e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HDDEELLK_00793 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
HDDEELLK_00794 4.5e-43 gutM K Glucitol operon activator protein (GutM)
HDDEELLK_00795 2.2e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HDDEELLK_00796 4e-110 IQ NAD dependent epimerase/dehydratase family
HDDEELLK_00797 1.6e-49 M Phage tail tape measure protein TP901
HDDEELLK_00800 6e-32 S Phage minor capsid protein 2
HDDEELLK_00801 2.3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
HDDEELLK_00802 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDDEELLK_00803 2.2e-266 fbp 3.1.3.11 G phosphatase activity
HDDEELLK_00804 1.4e-70 xerD L Phage integrase, N-terminal SAM-like domain
HDDEELLK_00810 1.9e-56 K LytTr DNA-binding domain
HDDEELLK_00811 7.5e-58 2.7.13.3 T GHKL domain
HDDEELLK_00814 1.9e-13
HDDEELLK_00815 7.2e-08
HDDEELLK_00818 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
HDDEELLK_00819 7.7e-82 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HDDEELLK_00820 1.3e-66 S Protein of unknown function (DUF1440)
HDDEELLK_00821 7.7e-41 S Iron-sulfur cluster assembly protein
HDDEELLK_00822 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HDDEELLK_00823 1.6e-72 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HDDEELLK_00824 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDDEELLK_00825 7.9e-155 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDDEELLK_00826 6.1e-65 G Xylose isomerase domain protein TIM barrel
HDDEELLK_00827 6.5e-90 nanK GK ROK family
HDDEELLK_00828 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HDDEELLK_00829 3.3e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HDDEELLK_00830 4.3e-75 K Helix-turn-helix domain, rpiR family
HDDEELLK_00831 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
HDDEELLK_00832 7e-217 yjeM E Amino Acid
HDDEELLK_00834 1.9e-25 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDDEELLK_00835 2e-232 tetP J elongation factor G
HDDEELLK_00836 2.1e-277 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDDEELLK_00837 6e-88 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HDDEELLK_00838 1.1e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HDDEELLK_00839 1.2e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HDDEELLK_00840 8.1e-182 gatC G PTS system sugar-specific permease component
HDDEELLK_00841 2e-35 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HDDEELLK_00842 2.7e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDDEELLK_00843 5e-23 S by MetaGeneAnnotator
HDDEELLK_00844 3.1e-06 M domain protein
HDDEELLK_00845 2.1e-27 3.4.22.70 M Sortase family
HDDEELLK_00846 1.2e-87 M Gram-positive pilin backbone subunit 2, Cna-B-like domain
HDDEELLK_00847 1.4e-44 3.4.22.70 M Sortase family
HDDEELLK_00850 2.3e-25 L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDDEELLK_00851 2e-57 S AAA domain, putative AbiEii toxin, Type IV TA system
HDDEELLK_00852 5.6e-13 S RloB-like protein
HDDEELLK_00853 4.4e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDDEELLK_00865 1.1e-21 ssb L Single-stranded DNA-binding protein
HDDEELLK_00866 1.7e-87 endA F DNA RNA non-specific endonuclease
HDDEELLK_00867 5.6e-133 NU StbA protein
HDDEELLK_00869 6.6e-08 S Uncharacterized protein pXO2-11
HDDEELLK_00870 4.3e-40
HDDEELLK_00871 3.8e-239 trsE S COG0433 Predicted ATPase
HDDEELLK_00873 3.3e-60 M Peptidase family M23
HDDEELLK_00876 4e-118 S Uncharacterised protein family (UPF0236)
HDDEELLK_00877 1.6e-114 ntpJ P Potassium uptake protein
HDDEELLK_00878 2.8e-58 ktrA P TrkA-N domain
HDDEELLK_00879 7.4e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HDDEELLK_00880 4.4e-37 M Glycosyltransferase group 2 family protein
HDDEELLK_00881 1.4e-19
HDDEELLK_00882 1.4e-94 S Predicted membrane protein (DUF2207)
HDDEELLK_00883 2.1e-54 bioY S BioY family
HDDEELLK_00884 1.3e-183 lmrB EGP Major facilitator Superfamily
HDDEELLK_00885 3.7e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDDEELLK_00886 7.6e-74 glcR K DeoR C terminal sensor domain
HDDEELLK_00887 7.7e-61 yceE S haloacid dehalogenase-like hydrolase
HDDEELLK_00888 1.7e-31 S CAAX protease self-immunity
HDDEELLK_00889 5.3e-34 S Domain of unknown function (DUF4811)
HDDEELLK_00890 2.1e-197 lmrB EGP Major facilitator Superfamily
HDDEELLK_00891 7.1e-32 merR K MerR HTH family regulatory protein
HDDEELLK_00892 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDDEELLK_00893 1.7e-69 S Protein of unknown function (DUF554)
HDDEELLK_00894 1.4e-120 G Bacterial extracellular solute-binding protein
HDDEELLK_00895 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
HDDEELLK_00896 2.3e-99 baeS T Histidine kinase
HDDEELLK_00897 2.4e-80 rbsB G sugar-binding domain protein
HDDEELLK_00898 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HDDEELLK_00899 6.4e-116 manY G PTS system sorbose-specific iic component
HDDEELLK_00900 8e-147 manN G system, mannose fructose sorbose family IID component
HDDEELLK_00901 1.8e-52 manO S Domain of unknown function (DUF956)
HDDEELLK_00902 3.6e-71 L PFAM transposase IS200-family protein
HDDEELLK_00903 4.3e-16 S Protein of unknown function (DUF805)
HDDEELLK_00905 2.3e-84 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDDEELLK_00906 9.2e-71 mltD CBM50 M NlpC P60 family protein
HDDEELLK_00907 5.2e-129 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDDEELLK_00908 8.4e-165 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDDEELLK_00909 4.1e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
HDDEELLK_00910 5.6e-46 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HDDEELLK_00911 8.1e-38 K transcriptional regulator PadR family
HDDEELLK_00912 7.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
HDDEELLK_00913 1.5e-15 S Putative adhesin
HDDEELLK_00914 7.5e-10 pspC KT PspC domain
HDDEELLK_00915 3.9e-13 S Enterocin A Immunity
HDDEELLK_00916 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDDEELLK_00917 1.6e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HDDEELLK_00918 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDDEELLK_00919 6.3e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDDEELLK_00920 1.5e-120 potB P ABC transporter permease
HDDEELLK_00921 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
HDDEELLK_00922 1.3e-159 potD P ABC transporter
HDDEELLK_00923 3.5e-132 ABC-SBP S ABC transporter
HDDEELLK_00924 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HDDEELLK_00925 5.2e-107 XK27_08845 S ABC transporter, ATP-binding protein
HDDEELLK_00926 4.4e-67 M ErfK YbiS YcfS YnhG
HDDEELLK_00927 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDDEELLK_00928 1.4e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDDEELLK_00929 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDDEELLK_00930 1.2e-102 pgm3 G phosphoglycerate mutase
HDDEELLK_00931 3.6e-56 S CAAX protease self-immunity
HDDEELLK_00932 4.8e-47 C Flavodoxin
HDDEELLK_00933 1.1e-55 yphH S Cupin domain
HDDEELLK_00934 1.4e-45 yphJ 4.1.1.44 S decarboxylase
HDDEELLK_00935 3.5e-144 E methionine synthase, vitamin-B12 independent
HDDEELLK_00936 1.8e-108 metQ1 P Belongs to the nlpA lipoprotein family
HDDEELLK_00937 2.6e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDDEELLK_00938 1.3e-69 metI P ABC transporter permease
HDDEELLK_00939 6.7e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HDDEELLK_00940 3e-84 drgA C nitroreductase
HDDEELLK_00941 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HDDEELLK_00942 2.3e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HDDEELLK_00943 1.3e-172 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDDEELLK_00944 1.7e-264 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HDDEELLK_00946 2.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDDEELLK_00947 2.4e-31 metI U ABC transporter permease
HDDEELLK_00948 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
HDDEELLK_00949 3.2e-58 S Protein of unknown function (DUF4256)
HDDEELLK_00951 0.0 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
HDDEELLK_00952 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HDDEELLK_00953 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HDDEELLK_00954 4.5e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDDEELLK_00955 4e-230 lpdA 1.8.1.4 C Dehydrogenase
HDDEELLK_00956 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
HDDEELLK_00957 9.2e-56 S Protein of unknown function (DUF975)
HDDEELLK_00958 1.3e-77 E GDSL-like Lipase/Acylhydrolase family
HDDEELLK_00959 1.8e-38
HDDEELLK_00960 9.2e-27 gcvR T Belongs to the UPF0237 family
HDDEELLK_00961 1.4e-219 XK27_08635 S UPF0210 protein
HDDEELLK_00962 4.5e-87 fruR K DeoR C terminal sensor domain
HDDEELLK_00963 9.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDDEELLK_00964 2.1e-282 fruA 2.7.1.202 GT Phosphotransferase System
HDDEELLK_00965 7e-50 cps3F
HDDEELLK_00966 2.7e-83 S Membrane
HDDEELLK_00967 2.4e-254 E Amino acid permease
HDDEELLK_00968 1e-225 cadA P P-type ATPase
HDDEELLK_00969 6.4e-114 degV S EDD domain protein, DegV family
HDDEELLK_00970 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HDDEELLK_00971 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
HDDEELLK_00972 7.5e-27 ydiI Q Thioesterase superfamily
HDDEELLK_00973 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HDDEELLK_00974 9.6e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HDDEELLK_00975 4.7e-81 S L,D-transpeptidase catalytic domain
HDDEELLK_00976 1.5e-165 EGP Major facilitator Superfamily
HDDEELLK_00977 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
HDDEELLK_00978 6e-226 pipD E Dipeptidase
HDDEELLK_00979 3.2e-118 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDDEELLK_00980 2.6e-32 ywjH S Protein of unknown function (DUF1634)
HDDEELLK_00981 2.2e-119 yxaA S membrane transporter protein
HDDEELLK_00982 7.6e-83 lysR5 K LysR substrate binding domain
HDDEELLK_00983 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
HDDEELLK_00984 9.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDDEELLK_00985 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HDDEELLK_00986 1.2e-68 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HDDEELLK_00987 1.6e-242 lysP E amino acid
HDDEELLK_00988 4.8e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDDEELLK_00990 3.2e-11 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDDEELLK_00991 2.7e-117 K Primase C terminal 1 (PriCT-1)
HDDEELLK_00993 2.8e-12 S Thioredoxin
HDDEELLK_00995 5.7e-07 L Integrase core domain
HDDEELLK_00996 3.2e-40
HDDEELLK_01001 1.9e-08 2.3.1.19 K Cro/C1-type HTH DNA-binding domain
HDDEELLK_01007 2.6e-16 S RelB antitoxin
HDDEELLK_01009 1.8e-26
HDDEELLK_01011 9.3e-16
HDDEELLK_01017 2.9e-61 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HDDEELLK_01018 1.1e-13
HDDEELLK_01028 1.6e-20 ada 3.2.2.21 F DNA/RNA non-specific endonuclease
HDDEELLK_01030 5.1e-16
HDDEELLK_01031 5.9e-141 ruvB 3.6.4.12 L four-way junction helicase activity
HDDEELLK_01036 3.2e-73
HDDEELLK_01038 6.4e-48 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDDEELLK_01040 3.1e-193 clpB O Belongs to the ClpA ClpB family
HDDEELLK_01043 4.1e-11
HDDEELLK_01044 5e-257 U COG3505 Type IV secretory pathway, VirD4 components
HDDEELLK_01045 1.1e-81
HDDEELLK_01046 2.7e-07 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
HDDEELLK_01049 4.5e-09 D Antitoxin Phd_YefM, type II toxin-antitoxin system
HDDEELLK_01050 5.1e-08 XK27_10540 S ParE toxin of type II toxin-antitoxin system, parDE
HDDEELLK_01051 1.3e-174 2.1.1.72, 3.1.21.3 V HsdM N-terminal domain
HDDEELLK_01055 2.9e-18 D nuclear chromosome segregation
HDDEELLK_01065 1e-54 tlpA2 L Transposase IS200 like
HDDEELLK_01075 2.9e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HDDEELLK_01076 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDDEELLK_01077 3.7e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDDEELLK_01078 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HDDEELLK_01079 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDDEELLK_01081 1.6e-55 ctsR K Belongs to the CtsR family
HDDEELLK_01082 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDDEELLK_01083 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDDEELLK_01084 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDDEELLK_01085 4.3e-23 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HDDEELLK_01086 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDDEELLK_01087 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDDEELLK_01088 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDDEELLK_01089 3.4e-92 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HDDEELLK_01090 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
HDDEELLK_01091 2.5e-113 K response regulator
HDDEELLK_01092 1.7e-141 hpk31 2.7.13.3 T Histidine kinase
HDDEELLK_01093 1.7e-90 lacX 5.1.3.3 G Aldose 1-epimerase
HDDEELLK_01094 8.6e-146 G Transporter, major facilitator family protein
HDDEELLK_01095 7e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDDEELLK_01096 5.6e-246 yhcA V ABC transporter, ATP-binding protein
HDDEELLK_01097 5.8e-35 K Bacterial regulatory proteins, tetR family
HDDEELLK_01098 8.9e-224 lmrA V ABC transporter, ATP-binding protein
HDDEELLK_01099 7.4e-253 yfiC V ABC transporter
HDDEELLK_01101 1.1e-45 yjcF K protein acetylation
HDDEELLK_01102 1.4e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
HDDEELLK_01103 8.7e-72 lemA S LemA family
HDDEELLK_01104 1.3e-114 htpX O Belongs to the peptidase M48B family
HDDEELLK_01106 8.8e-272 helD 3.6.4.12 L DNA helicase
HDDEELLK_01107 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDDEELLK_01108 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDDEELLK_01109 2.1e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HDDEELLK_01110 4.2e-82 ybhF_2 V abc transporter atp-binding protein
HDDEELLK_01111 2.7e-104 ybhR V ABC transporter
HDDEELLK_01112 1.8e-31 K Transcriptional regulator
HDDEELLK_01113 1.9e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
HDDEELLK_01114 2.3e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HDDEELLK_01115 5.1e-128
HDDEELLK_01116 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDDEELLK_01117 1e-102 tatD L hydrolase, TatD family
HDDEELLK_01118 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDDEELLK_01119 3.7e-133 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDDEELLK_01120 2.7e-22 veg S Biofilm formation stimulator VEG
HDDEELLK_01121 2.9e-90 S Alpha/beta hydrolase of unknown function (DUF915)
HDDEELLK_01122 7.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
HDDEELLK_01123 6.6e-46 argR K Regulates arginine biosynthesis genes
HDDEELLK_01124 1.8e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDDEELLK_01125 1.6e-156 amtB P ammonium transporter
HDDEELLK_01126 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
HDDEELLK_01127 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDDEELLK_01128 3.4e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HDDEELLK_01129 4.9e-126 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDDEELLK_01130 4.3e-104 pfoS S Phosphotransferase system, EIIC
HDDEELLK_01134 7.7e-08 L Helix-turn-helix domain
HDDEELLK_01135 9.3e-19 M domain protein
HDDEELLK_01136 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDDEELLK_01137 1.1e-52 adhR K helix_turn_helix, mercury resistance
HDDEELLK_01138 5.2e-137 purR 2.4.2.7 F pur operon repressor
HDDEELLK_01139 1.9e-47 EGP Transmembrane secretion effector
HDDEELLK_01140 1.7e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDDEELLK_01141 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDDEELLK_01142 1.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDDEELLK_01144 1.2e-112 dkg S reductase
HDDEELLK_01145 1.7e-24
HDDEELLK_01146 5.1e-78 2.4.2.3 F Phosphorylase superfamily
HDDEELLK_01147 3.9e-290 ybiT S ABC transporter, ATP-binding protein
HDDEELLK_01148 3.9e-63 bCE_4747 S Beta-lactamase superfamily domain
HDDEELLK_01149 2.2e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDDEELLK_01150 1e-124 S overlaps another CDS with the same product name
HDDEELLK_01151 1.7e-86 S overlaps another CDS with the same product name
HDDEELLK_01153 6.7e-56 spoVK O ATPase family associated with various cellular activities (AAA)
HDDEELLK_01154 1.9e-21
HDDEELLK_01155 5.4e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HDDEELLK_01157 7e-73
HDDEELLK_01158 2.2e-27
HDDEELLK_01159 7.7e-105 ydcZ S Putative inner membrane exporter, YdcZ
HDDEELLK_01160 4.4e-88 S hydrolase
HDDEELLK_01161 8.6e-206 ywfO S HD domain protein
HDDEELLK_01162 9.8e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
HDDEELLK_01163 6.3e-33 ywiB S Domain of unknown function (DUF1934)
HDDEELLK_01164 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDDEELLK_01165 1.6e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDDEELLK_01167 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDDEELLK_01168 5.3e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HDDEELLK_01169 1.4e-40 rpmE2 J Ribosomal protein L31
HDDEELLK_01170 2.2e-61
HDDEELLK_01171 1.2e-255 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HDDEELLK_01173 1.6e-79 S Cell surface protein
HDDEELLK_01175 1.2e-180 pbuG S permease
HDDEELLK_01176 3.8e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
HDDEELLK_01177 4.1e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDDEELLK_01178 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDDEELLK_01179 3.9e-40 tlpA2 L Transposase IS200 like
HDDEELLK_01180 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDDEELLK_01181 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDDEELLK_01182 5.4e-13
HDDEELLK_01183 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
HDDEELLK_01184 2.5e-91 yunF F Protein of unknown function DUF72
HDDEELLK_01185 2.9e-156 nrnB S DHHA1 domain
HDDEELLK_01186 7.1e-19 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDDEELLK_01187 7.6e-60
HDDEELLK_01188 2.9e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
HDDEELLK_01189 2e-22 S Cytochrome B5
HDDEELLK_01190 8.1e-20 sigH K DNA-templated transcription, initiation
HDDEELLK_01191 6.9e-70 recX 2.4.1.337 GT4 S Regulatory protein RecX
HDDEELLK_01192 1e-119 sip L Belongs to the 'phage' integrase family
HDDEELLK_01193 2.1e-15 K Transcriptional regulator, Cro CI family
HDDEELLK_01194 1.5e-07 K Helix-turn-helix XRE-family like proteins
HDDEELLK_01195 6.2e-45 S Phage regulatory protein Rha (Phage_pRha)
HDDEELLK_01200 5.7e-20
HDDEELLK_01202 1.5e-37 ybl78 L Conserved phage C-terminus (Phg_2220_C)
HDDEELLK_01203 3.7e-09 arpU S Phage transcriptional regulator, ArpU family
HDDEELLK_01204 2.3e-16
HDDEELLK_01205 8.5e-193 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDDEELLK_01206 2.6e-97 ygaC J Belongs to the UPF0374 family
HDDEELLK_01207 6.9e-92 yueF S AI-2E family transporter
HDDEELLK_01208 3.2e-157 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HDDEELLK_01209 1.8e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDDEELLK_01210 1.5e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDDEELLK_01211 0.0 lacL 3.2.1.23 G -beta-galactosidase
HDDEELLK_01212 7.5e-288 lacS G Transporter
HDDEELLK_01213 5.9e-111 galR K Transcriptional regulator
HDDEELLK_01214 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDDEELLK_01215 8.6e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDDEELLK_01216 1.2e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HDDEELLK_01217 3e-311 rafA 3.2.1.22 G alpha-galactosidase
HDDEELLK_01218 1.7e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HDDEELLK_01219 1.5e-22 XK27_09445 S Domain of unknown function (DUF1827)
HDDEELLK_01220 0.0 clpE O Belongs to the ClpA ClpB family
HDDEELLK_01221 1.5e-15
HDDEELLK_01222 9.7e-37 ptsH G phosphocarrier protein HPR
HDDEELLK_01223 2e-284 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDDEELLK_01224 2e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HDDEELLK_01225 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
HDDEELLK_01226 5.2e-131 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDDEELLK_01227 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
HDDEELLK_01228 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDDEELLK_01230 2.1e-07
HDDEELLK_01238 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDDEELLK_01239 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDDEELLK_01240 2.4e-192 cycA E Amino acid permease
HDDEELLK_01241 8.3e-187 ytgP S Polysaccharide biosynthesis protein
HDDEELLK_01242 5.7e-63 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDDEELLK_01243 5.4e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDDEELLK_01244 6.6e-193 pepV 3.5.1.18 E dipeptidase PepV
HDDEELLK_01245 2.1e-215 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HDDEELLK_01247 1.2e-84 V AAA domain (dynein-related subfamily)
HDDEELLK_01248 5.8e-68 S LlaJI restriction endonuclease
HDDEELLK_01251 1.5e-35
HDDEELLK_01252 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDDEELLK_01253 4.2e-61 marR K Transcriptional regulator, MarR family
HDDEELLK_01254 2.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDDEELLK_01255 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDDEELLK_01256 2.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HDDEELLK_01257 1.1e-98 IQ reductase
HDDEELLK_01258 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDDEELLK_01259 4.6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDDEELLK_01260 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDDEELLK_01261 4.2e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HDDEELLK_01262 1.4e-124 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDDEELLK_01263 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HDDEELLK_01264 9.3e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HDDEELLK_01265 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDDEELLK_01266 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
HDDEELLK_01267 5.5e-303 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDDEELLK_01268 5.7e-119 gla U Major intrinsic protein
HDDEELLK_01269 1.5e-45 ykuL S CBS domain
HDDEELLK_01270 8.8e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDDEELLK_01271 1.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDDEELLK_01272 9e-87 ykuT M mechanosensitive ion channel
HDDEELLK_01274 1e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDDEELLK_01275 2e-21 yheA S Belongs to the UPF0342 family
HDDEELLK_01276 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDDEELLK_01277 2.5e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDDEELLK_01279 5.4e-53 hit FG histidine triad
HDDEELLK_01280 9.8e-95 ecsA V ABC transporter, ATP-binding protein
HDDEELLK_01281 1.9e-71 ecsB U ABC transporter
HDDEELLK_01282 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HDDEELLK_01283 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDDEELLK_01284 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDDEELLK_01285 8.1e-77 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDDEELLK_01286 1.4e-240 sftA D Belongs to the FtsK SpoIIIE SftA family
HDDEELLK_01287 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HDDEELLK_01288 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
HDDEELLK_01289 5.2e-69 ybhL S Belongs to the BI1 family
HDDEELLK_01290 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDDEELLK_01291 1.5e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDDEELLK_01292 3.5e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDDEELLK_01293 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDDEELLK_01294 1.6e-79 dnaB L replication initiation and membrane attachment
HDDEELLK_01295 1.3e-107 dnaI L Primosomal protein DnaI
HDDEELLK_01296 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDDEELLK_01297 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDDEELLK_01298 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HDDEELLK_01299 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDDEELLK_01300 1.6e-70 yqeG S HAD phosphatase, family IIIA
HDDEELLK_01301 4.6e-181 yqeH S Ribosome biogenesis GTPase YqeH
HDDEELLK_01302 6e-30 yhbY J RNA-binding protein
HDDEELLK_01303 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDDEELLK_01304 2.6e-69 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HDDEELLK_01305 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDDEELLK_01306 6.5e-83 H Nodulation protein S (NodS)
HDDEELLK_01307 4.5e-123 ylbM S Belongs to the UPF0348 family
HDDEELLK_01308 2.3e-56 yceD S Uncharacterized ACR, COG1399
HDDEELLK_01309 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HDDEELLK_01310 4e-89 plsC 2.3.1.51 I Acyltransferase
HDDEELLK_01311 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
HDDEELLK_01312 1.5e-27 yazA L GIY-YIG catalytic domain protein
HDDEELLK_01313 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
HDDEELLK_01314 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDDEELLK_01315 6.9e-37
HDDEELLK_01316 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HDDEELLK_01317 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDDEELLK_01318 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDDEELLK_01319 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDDEELLK_01320 1.7e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDDEELLK_01322 3.1e-111 K response regulator
HDDEELLK_01323 1.3e-167 arlS 2.7.13.3 T Histidine kinase
HDDEELLK_01324 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDDEELLK_01325 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HDDEELLK_01326 1.8e-135 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HDDEELLK_01327 7.3e-105
HDDEELLK_01328 5.5e-117
HDDEELLK_01329 6.5e-41 dut S dUTPase
HDDEELLK_01330 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDDEELLK_01331 3.7e-46 yqhY S Asp23 family, cell envelope-related function
HDDEELLK_01332 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDDEELLK_01333 3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDDEELLK_01334 5.8e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDDEELLK_01335 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDDEELLK_01336 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDDEELLK_01337 2.6e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HDDEELLK_01338 6.6e-49 argR K Regulates arginine biosynthesis genes
HDDEELLK_01339 9.3e-178 recN L May be involved in recombinational repair of damaged DNA
HDDEELLK_01340 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDDEELLK_01341 2.2e-30 ynzC S UPF0291 protein
HDDEELLK_01342 5.9e-27 yneF S UPF0154 protein
HDDEELLK_01343 1.6e-92 engB D Necessary for normal cell division and for the maintenance of normal septation
HDDEELLK_01344 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HDDEELLK_01345 2.9e-76 yciQ P membrane protein (DUF2207)
HDDEELLK_01346 1.8e-19 D nuclear chromosome segregation
HDDEELLK_01347 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDDEELLK_01348 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDDEELLK_01349 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
HDDEELLK_01350 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
HDDEELLK_01351 4.7e-158 glk 2.7.1.2 G Glucokinase
HDDEELLK_01352 1.4e-45 yqhL P Rhodanese-like protein
HDDEELLK_01353 2.8e-16 WQ51_02665 S Protein of unknown function (DUF3042)
HDDEELLK_01354 5.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDDEELLK_01355 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
HDDEELLK_01356 1.3e-45 glnR K Transcriptional regulator
HDDEELLK_01357 2e-247 glnA 6.3.1.2 E glutamine synthetase
HDDEELLK_01359 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HDDEELLK_01360 2.7e-48 S Domain of unknown function (DUF956)
HDDEELLK_01361 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HDDEELLK_01362 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDDEELLK_01363 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDDEELLK_01364 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
HDDEELLK_01365 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HDDEELLK_01366 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDDEELLK_01367 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDDEELLK_01368 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
HDDEELLK_01369 4.8e-170 nusA K Participates in both transcription termination and antitermination
HDDEELLK_01370 1.4e-39 ylxR K Protein of unknown function (DUF448)
HDDEELLK_01371 6.9e-26 ylxQ J ribosomal protein
HDDEELLK_01372 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDDEELLK_01373 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDDEELLK_01374 8.2e-120 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDDEELLK_01375 5.1e-96 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HDDEELLK_01376 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDDEELLK_01377 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDDEELLK_01378 4.5e-274 dnaK O Heat shock 70 kDa protein
HDDEELLK_01379 9.2e-161 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDDEELLK_01380 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDDEELLK_01382 4.6e-205 glnP P ABC transporter
HDDEELLK_01383 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDDEELLK_01384 1.5e-31
HDDEELLK_01385 5.9e-111 ampC V Beta-lactamase
HDDEELLK_01386 2.7e-110 cobQ S glutamine amidotransferase
HDDEELLK_01387 2.3e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HDDEELLK_01388 6.8e-86 tdk 2.7.1.21 F thymidine kinase
HDDEELLK_01389 1.3e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDDEELLK_01390 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDDEELLK_01391 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDDEELLK_01392 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDDEELLK_01393 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
HDDEELLK_01394 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDDEELLK_01395 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDDEELLK_01396 2.4e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDDEELLK_01397 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDDEELLK_01398 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDDEELLK_01399 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDDEELLK_01400 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HDDEELLK_01401 4.1e-15 ywzB S Protein of unknown function (DUF1146)
HDDEELLK_01402 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDDEELLK_01403 1.2e-167 mbl D Cell shape determining protein MreB Mrl
HDDEELLK_01404 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HDDEELLK_01405 1.3e-13 S Protein of unknown function (DUF2969)
HDDEELLK_01406 6.1e-187 rodA D Belongs to the SEDS family
HDDEELLK_01407 2.1e-26 arsC 1.20.4.1 P Belongs to the ArsC family
HDDEELLK_01408 9.5e-94 2.7.1.89 M Phosphotransferase enzyme family
HDDEELLK_01409 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HDDEELLK_01410 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDDEELLK_01411 3.7e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDDEELLK_01412 1.6e-287 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDDEELLK_01413 4.4e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDDEELLK_01414 2.6e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDDEELLK_01415 1.9e-90 stp 3.1.3.16 T phosphatase
HDDEELLK_01416 5.7e-191 KLT serine threonine protein kinase
HDDEELLK_01417 1.1e-108 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDDEELLK_01418 7.7e-59 thiN 2.7.6.2 H thiamine pyrophosphokinase
HDDEELLK_01419 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HDDEELLK_01420 4.5e-53 asp S Asp23 family, cell envelope-related function
HDDEELLK_01421 2.5e-239 yloV S DAK2 domain fusion protein YloV
HDDEELLK_01422 6.7e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDDEELLK_01423 4.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDDEELLK_01424 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDDEELLK_01425 3.9e-101 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDDEELLK_01426 2.7e-211 smc D Required for chromosome condensation and partitioning
HDDEELLK_01427 9.1e-149 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDDEELLK_01428 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDDEELLK_01429 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDDEELLK_01430 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HDDEELLK_01431 1.1e-26 ylqC S Belongs to the UPF0109 family
HDDEELLK_01432 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDDEELLK_01433 1.6e-113 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HDDEELLK_01434 4.4e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
HDDEELLK_01435 1.3e-196 yfnA E amino acid
HDDEELLK_01436 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDDEELLK_01437 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
HDDEELLK_01438 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDDEELLK_01439 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDDEELLK_01440 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDDEELLK_01441 1.8e-18 S Tetratricopeptide repeat
HDDEELLK_01442 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDDEELLK_01443 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDDEELLK_01444 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDDEELLK_01445 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDDEELLK_01446 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDDEELLK_01447 2.5e-22 ykzG S Belongs to the UPF0356 family
HDDEELLK_01448 5.5e-25
HDDEELLK_01449 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDDEELLK_01450 1.7e-32 1.1.1.27 C L-malate dehydrogenase activity
HDDEELLK_01451 2.2e-23 yktA S Belongs to the UPF0223 family
HDDEELLK_01452 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HDDEELLK_01453 0.0 typA T GTP-binding protein TypA
HDDEELLK_01454 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HDDEELLK_01455 7e-115 manY G PTS system
HDDEELLK_01456 3.3e-148 manN G system, mannose fructose sorbose family IID component
HDDEELLK_01457 3e-101 ftsW D Belongs to the SEDS family
HDDEELLK_01458 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HDDEELLK_01459 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HDDEELLK_01460 1.1e-71 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HDDEELLK_01461 1.5e-48 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDDEELLK_01462 2.4e-131 ylbL T Belongs to the peptidase S16 family
HDDEELLK_01463 2.9e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HDDEELLK_01464 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDDEELLK_01465 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDDEELLK_01466 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDDEELLK_01467 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDDEELLK_01468 9e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HDDEELLK_01469 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDDEELLK_01470 5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HDDEELLK_01471 6e-161 purD 6.3.4.13 F Belongs to the GARS family
HDDEELLK_01472 3.2e-107 S Acyltransferase family
HDDEELLK_01473 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDDEELLK_01474 5e-122 K LysR substrate binding domain
HDDEELLK_01476 2.2e-20
HDDEELLK_01477 4.7e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HDDEELLK_01478 1.3e-267 argS 6.1.1.19 J Arginyl-tRNA synthetase
HDDEELLK_01479 1.4e-50 comEA L Competence protein ComEA
HDDEELLK_01480 2e-69 comEB 3.5.4.12 F ComE operon protein 2
HDDEELLK_01481 1.6e-156 comEC S Competence protein ComEC
HDDEELLK_01482 8.4e-105 holA 2.7.7.7 L DNA polymerase III delta subunit
HDDEELLK_01483 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDDEELLK_01484 6.7e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HDDEELLK_01485 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HDDEELLK_01486 4.7e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HDDEELLK_01487 2.3e-229 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HDDEELLK_01488 4.2e-33 ypmB S Protein conserved in bacteria
HDDEELLK_01489 9e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HDDEELLK_01490 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HDDEELLK_01491 7.2e-55 dnaD L DnaD domain protein
HDDEELLK_01492 6.3e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDDEELLK_01493 7.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDDEELLK_01494 1.3e-125 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDDEELLK_01495 8.6e-94 M transferase activity, transferring glycosyl groups
HDDEELLK_01496 2.8e-84 M Glycosyltransferase sugar-binding region containing DXD motif
HDDEELLK_01497 1.2e-100 epsJ1 M Glycosyltransferase like family 2
HDDEELLK_01500 2.2e-116 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDDEELLK_01501 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HDDEELLK_01502 1.8e-56 yqeY S YqeY-like protein
HDDEELLK_01504 1.8e-68 xerD L Phage integrase, N-terminal SAM-like domain
HDDEELLK_01505 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDDEELLK_01506 8.2e-108 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDDEELLK_01507 2.5e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDDEELLK_01508 5e-276 yfmR S ABC transporter, ATP-binding protein
HDDEELLK_01509 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDDEELLK_01510 5.5e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDDEELLK_01511 7.3e-134 yvgN C Aldo keto reductase
HDDEELLK_01512 1.1e-35 K helix_turn_helix, mercury resistance
HDDEELLK_01513 2.7e-113 S Aldo keto reductase
HDDEELLK_01515 4.5e-81 ypmR E GDSL-like Lipase/Acylhydrolase
HDDEELLK_01516 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HDDEELLK_01517 3.6e-24 yozE S Belongs to the UPF0346 family
HDDEELLK_01518 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDDEELLK_01519 1.1e-96 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDDEELLK_01520 1.4e-84 dprA LU DNA protecting protein DprA
HDDEELLK_01521 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDDEELLK_01522 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDDEELLK_01523 5.8e-205 G PTS system Galactitol-specific IIC component
HDDEELLK_01524 2.1e-153 M Exporter of polyketide antibiotics
HDDEELLK_01525 1.4e-37 cas6 S Pfam:DUF2276
HDDEELLK_01526 2.6e-207 csm1 S CRISPR-associated protein Csm1 family
HDDEELLK_01527 6.7e-28 csm2 L Csm2 Type III-A
HDDEELLK_01528 2.6e-70 csm3 L RAMP superfamily
HDDEELLK_01529 2.5e-60 csm4 L CRISPR-associated RAMP protein, Csm4 family
HDDEELLK_01530 4.3e-66 csm5 L RAMP superfamily
HDDEELLK_01531 4.9e-88 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDDEELLK_01532 1.2e-30 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDDEELLK_01533 2.5e-71 csm6 S Psort location Cytoplasmic, score
HDDEELLK_01534 1.1e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HDDEELLK_01535 1.1e-44 S Repeat protein
HDDEELLK_01536 5.3e-278 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDDEELLK_01539 2.2e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDDEELLK_01540 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDDEELLK_01541 9.1e-43 yodB K Transcriptional regulator, HxlR family
HDDEELLK_01542 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDDEELLK_01543 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDDEELLK_01544 4.3e-126 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDDEELLK_01545 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
HDDEELLK_01546 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDDEELLK_01547 6.4e-12
HDDEELLK_01548 3.9e-144 iunH2 3.2.2.1 F nucleoside hydrolase
HDDEELLK_01549 1.7e-42 XK27_03960 S Protein of unknown function (DUF3013)
HDDEELLK_01550 4.4e-118 prmA J Ribosomal protein L11 methyltransferase
HDDEELLK_01551 6.3e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDDEELLK_01552 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDDEELLK_01553 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDDEELLK_01554 5.7e-56 3.1.3.18 J HAD-hyrolase-like
HDDEELLK_01555 2.3e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDDEELLK_01556 1.6e-128 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDDEELLK_01557 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDDEELLK_01558 3.5e-204 pyrP F Permease
HDDEELLK_01559 2.2e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDDEELLK_01560 2.9e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HDDEELLK_01561 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDDEELLK_01562 3.3e-88 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDDEELLK_01563 4.7e-134 K Transcriptional regulator
HDDEELLK_01564 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
HDDEELLK_01565 1.1e-114 glcR K DeoR C terminal sensor domain
HDDEELLK_01566 9.1e-172 patA 2.6.1.1 E Aminotransferase
HDDEELLK_01567 9.2e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDDEELLK_01569 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDDEELLK_01570 6.1e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HDDEELLK_01571 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
HDDEELLK_01572 8.1e-21 S Family of unknown function (DUF5322)
HDDEELLK_01573 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HDDEELLK_01574 1.8e-38
HDDEELLK_01579 7.2e-13 V PFAM secretion protein HlyD family protein
HDDEELLK_01580 9.6e-149 EGP Sugar (and other) transporter
HDDEELLK_01581 7.8e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
HDDEELLK_01582 1.9e-104 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDDEELLK_01583 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDDEELLK_01584 3.9e-71 alkD L DNA alkylation repair enzyme
HDDEELLK_01585 4.9e-136 EG EamA-like transporter family
HDDEELLK_01586 2.8e-150 S Tetratricopeptide repeat protein
HDDEELLK_01587 3.4e-204 hisS 6.1.1.21 J histidyl-tRNA synthetase
HDDEELLK_01588 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDDEELLK_01589 5.4e-127 corA P CorA-like Mg2+ transporter protein
HDDEELLK_01590 1.9e-160 nhaC C Na H antiporter NhaC
HDDEELLK_01591 7.2e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDDEELLK_01592 2.6e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HDDEELLK_01594 1.9e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDDEELLK_01595 2.3e-159 iscS 2.8.1.7 E Aminotransferase class V
HDDEELLK_01596 3.7e-41 XK27_04120 S Putative amino acid metabolism
HDDEELLK_01597 1.6e-202 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDDEELLK_01598 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDDEELLK_01599 4.3e-15 S Protein of unknown function (DUF2929)
HDDEELLK_01600 0.0 dnaE 2.7.7.7 L DNA polymerase
HDDEELLK_01601 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDDEELLK_01602 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HDDEELLK_01604 1e-39 ypaA S Protein of unknown function (DUF1304)
HDDEELLK_01605 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDDEELLK_01606 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDDEELLK_01607 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDDEELLK_01608 4.2e-202 FbpA K Fibronectin-binding protein
HDDEELLK_01609 3.1e-40 K Transcriptional regulator
HDDEELLK_01610 1.8e-51 degV S EDD domain protein, DegV family
HDDEELLK_01611 3.7e-50 degV S EDD domain protein, DegV family
HDDEELLK_01612 1.5e-69 lepB 3.4.21.89 U Signal peptidase, peptidase S26
HDDEELLK_01613 2.4e-40 6.3.3.2 S ASCH
HDDEELLK_01614 6.3e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDDEELLK_01615 7e-81 yjjH S Calcineurin-like phosphoesterase
HDDEELLK_01616 1.8e-95 EG EamA-like transporter family
HDDEELLK_01617 2.5e-84 natB CP ABC-type Na efflux pump, permease component
HDDEELLK_01618 6.2e-112 natA S Domain of unknown function (DUF4162)
HDDEELLK_01619 3.7e-23 K Acetyltransferase (GNAT) domain
HDDEELLK_01621 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDDEELLK_01622 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HDDEELLK_01623 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
HDDEELLK_01624 1.4e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
HDDEELLK_01625 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDDEELLK_01626 1.4e-28 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDDEELLK_01627 1.2e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
HDDEELLK_01628 2e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDDEELLK_01629 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
HDDEELLK_01630 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
HDDEELLK_01631 1e-154 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDDEELLK_01632 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HDDEELLK_01633 1.2e-58 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDDEELLK_01634 3.5e-153 phoH T phosphate starvation-inducible protein PhoH
HDDEELLK_01635 1.5e-83 lytH 3.5.1.28 M Ami_3
HDDEELLK_01636 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HDDEELLK_01637 7.7e-12 M Lysin motif
HDDEELLK_01638 1e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HDDEELLK_01639 4.9e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
HDDEELLK_01640 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
HDDEELLK_01641 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HDDEELLK_01642 1.4e-120 ica2 GT2 M Glycosyl transferase family group 2
HDDEELLK_01643 1.7e-44
HDDEELLK_01644 9.5e-92 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDDEELLK_01646 3.7e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDDEELLK_01647 1.4e-214 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDDEELLK_01648 2.5e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HDDEELLK_01649 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HDDEELLK_01650 1.1e-109 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
HDDEELLK_01651 4.4e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDDEELLK_01653 3e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
HDDEELLK_01654 5.7e-57 3.6.1.27 I Acid phosphatase homologues
HDDEELLK_01655 3e-68 maa 2.3.1.79 S Maltose acetyltransferase
HDDEELLK_01656 1.3e-73 2.3.1.178 M GNAT acetyltransferase
HDDEELLK_01658 3.9e-08 XK27_10540 S ParE toxin of type II toxin-antitoxin system, parDE
HDDEELLK_01659 1e-08 D Antitoxin Phd_YefM, type II toxin-antitoxin system
HDDEELLK_01660 5.5e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HDDEELLK_01661 4.3e-63 ypsA S Belongs to the UPF0398 family
HDDEELLK_01662 3.7e-188 nhaC C Na H antiporter NhaC
HDDEELLK_01663 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDDEELLK_01664 1.9e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HDDEELLK_01665 1.2e-112 xerD D recombinase XerD
HDDEELLK_01666 1.8e-124 cvfB S S1 domain
HDDEELLK_01667 4.1e-51 yeaL S Protein of unknown function (DUF441)
HDDEELLK_01668 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDDEELLK_01669 3.4e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDDEELLK_01670 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDDEELLK_01671 2e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDDEELLK_01672 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDDEELLK_01673 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDDEELLK_01674 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDDEELLK_01675 7.9e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HDDEELLK_01676 6.6e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HDDEELLK_01677 1.8e-101 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HDDEELLK_01678 1.4e-71
HDDEELLK_01680 3.7e-12
HDDEELLK_01681 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HDDEELLK_01682 1e-27 ysxB J Cysteine protease Prp
HDDEELLK_01683 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
HDDEELLK_01686 1e-59 S RRXRR protein
HDDEELLK_01688 2.2e-08 S Protein of unknown function (DUF2922)
HDDEELLK_01690 3.7e-16 K DNA-templated transcription, initiation
HDDEELLK_01692 1.5e-66 H Methyltransferase domain
HDDEELLK_01693 1.4e-77 cps2D 5.1.3.2 M RmlD substrate binding domain
HDDEELLK_01694 3.3e-41 wecD M Acetyltransferase (GNAT) family
HDDEELLK_01696 1.8e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
HDDEELLK_01697 3.4e-41 S Protein of unknown function (DUF1211)
HDDEELLK_01699 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
HDDEELLK_01700 2.7e-30 S CHY zinc finger
HDDEELLK_01701 5.2e-11 K Transcriptional regulator
HDDEELLK_01702 1.5e-21 K Transcriptional regulator
HDDEELLK_01703 1.2e-83 qorB 1.6.5.2 GM NmrA-like family
HDDEELLK_01704 5.8e-10
HDDEELLK_01705 2.6e-70 M Glycosyl transferases group 1
HDDEELLK_01706 1.1e-71 M Glycosyl transferases group 1
HDDEELLK_01707 2.4e-178 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HDDEELLK_01708 1.1e-144 lspL 5.1.3.6 GM RmlD substrate binding domain
HDDEELLK_01709 7.7e-102 cps2I S Psort location CytoplasmicMembrane, score
HDDEELLK_01710 6.8e-116 S Glycosyltransferase WbsX
HDDEELLK_01711 1.5e-115 S Glycosyltransferase WbsX
HDDEELLK_01712 2.9e-16
HDDEELLK_01713 2.7e-25 S Psort location Cytoplasmic, score
HDDEELLK_01714 1.1e-06 S EpsG family
HDDEELLK_01715 2.7e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
HDDEELLK_01716 4.3e-41 GT2 S Glycosyltransferase
HDDEELLK_01717 4.4e-75 M Glycosyltransferase Family 4
HDDEELLK_01718 1e-82 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
HDDEELLK_01719 6.2e-122 2.4.1.52 GT4 M Glycosyl transferases group 1
HDDEELLK_01720 6.5e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
HDDEELLK_01721 2.3e-76 epsL M Bacterial sugar transferase
HDDEELLK_01722 2.4e-167 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
HDDEELLK_01723 3.8e-211 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM CoA-binding domain
HDDEELLK_01724 7.2e-65 cpsD D AAA domain
HDDEELLK_01725 1.2e-47 cps4C M Chain length determinant protein
HDDEELLK_01726 1.8e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HDDEELLK_01727 7.7e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HDDEELLK_01728 8.1e-81
HDDEELLK_01729 1.2e-82 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HDDEELLK_01730 2.3e-113 yitU 3.1.3.104 S hydrolase
HDDEELLK_01731 5.6e-60 speG J Acetyltransferase (GNAT) domain
HDDEELLK_01732 7e-189 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDDEELLK_01733 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HDDEELLK_01734 4.5e-205 pipD E Dipeptidase
HDDEELLK_01735 9.5e-44
HDDEELLK_01736 9.1e-65 K helix_turn_helix, arabinose operon control protein
HDDEELLK_01737 1.5e-53 S Membrane
HDDEELLK_01738 0.0 rafA 3.2.1.22 G alpha-galactosidase
HDDEELLK_01739 3.6e-60 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
HDDEELLK_01740 1.2e-308 L Helicase C-terminal domain protein
HDDEELLK_01741 1.1e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HDDEELLK_01742 5.9e-39 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HDDEELLK_01743 2.4e-113 2.7.7.65 T diguanylate cyclase activity
HDDEELLK_01744 0.0 ydaN S Bacterial cellulose synthase subunit
HDDEELLK_01745 1.2e-201 ydaM M Glycosyl transferase family group 2
HDDEELLK_01746 5.8e-206 S Protein conserved in bacteria
HDDEELLK_01747 7.1e-182
HDDEELLK_01748 3.3e-128 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HDDEELLK_01749 7.3e-44 2.7.7.65 T GGDEF domain
HDDEELLK_01750 6.2e-145 pbuO_1 S Permease family
HDDEELLK_01751 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
HDDEELLK_01752 4.4e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HDDEELLK_01753 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDDEELLK_01754 1.8e-219 cydD CO ABC transporter transmembrane region
HDDEELLK_01755 7.8e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HDDEELLK_01756 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HDDEELLK_01757 2.1e-194 cydA 1.10.3.14 C ubiquinol oxidase
HDDEELLK_01758 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
HDDEELLK_01759 3.1e-27 xlyB 3.5.1.28 CBM50 M LysM domain
HDDEELLK_01760 5e-19 glpE P Rhodanese Homology Domain
HDDEELLK_01761 4.2e-49 lytE M LysM domain protein
HDDEELLK_01762 2.6e-91 T Calcineurin-like phosphoesterase superfamily domain
HDDEELLK_01763 3.7e-84 2.7.7.12 C Domain of unknown function (DUF4931)
HDDEELLK_01765 1.3e-73 draG O ADP-ribosylglycohydrolase
HDDEELLK_01766 5.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDDEELLK_01767 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDDEELLK_01768 1.9e-61 divIVA D DivIVA domain protein
HDDEELLK_01769 3.5e-82 ylmH S S4 domain protein
HDDEELLK_01770 3e-19 yggT S YGGT family
HDDEELLK_01771 2.5e-32 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDDEELLK_01772 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDDEELLK_01773 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDDEELLK_01774 2.2e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDDEELLK_01775 8.9e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDDEELLK_01776 4.5e-186 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDDEELLK_01777 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDDEELLK_01778 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
HDDEELLK_01779 2.5e-11 ftsL D cell division protein FtsL
HDDEELLK_01780 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDDEELLK_01781 1.5e-55 mraZ K Belongs to the MraZ family
HDDEELLK_01783 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HDDEELLK_01785 9.8e-100 D Alpha beta
HDDEELLK_01786 3.7e-109 aatB ET ABC transporter substrate-binding protein
HDDEELLK_01787 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDDEELLK_01788 1.9e-94 glnP P ABC transporter permease
HDDEELLK_01789 1.8e-126 minD D Belongs to the ParA family
HDDEELLK_01790 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HDDEELLK_01791 1.5e-54 mreD M rod shape-determining protein MreD
HDDEELLK_01792 2.1e-88 mreC M Involved in formation and maintenance of cell shape
HDDEELLK_01793 3.6e-156 mreB D cell shape determining protein MreB
HDDEELLK_01794 4.5e-21 K Cold shock
HDDEELLK_01795 6.2e-80 radC L DNA repair protein
HDDEELLK_01796 3.7e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDDEELLK_01797 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDDEELLK_01798 3.2e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDDEELLK_01799 3.8e-162 iscS2 2.8.1.7 E Aminotransferase class V
HDDEELLK_01800 4.4e-175 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDDEELLK_01801 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
HDDEELLK_01802 6.3e-100 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDDEELLK_01803 2e-24 yueI S Protein of unknown function (DUF1694)
HDDEELLK_01804 5.2e-189 rarA L recombination factor protein RarA
HDDEELLK_01806 3.2e-73 usp6 T universal stress protein
HDDEELLK_01807 3.8e-54 tag 3.2.2.20 L glycosylase
HDDEELLK_01808 2.2e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDDEELLK_01809 3.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HDDEELLK_01812 1.5e-75 yviA S Protein of unknown function (DUF421)
HDDEELLK_01813 1.8e-27 S Protein of unknown function (DUF3290)
HDDEELLK_01814 2.3e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
HDDEELLK_01815 3.5e-296 S membrane
HDDEELLK_01816 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDDEELLK_01817 3.1e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
HDDEELLK_01818 5.8e-101 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HDDEELLK_01819 2.6e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDDEELLK_01821 1.4e-16
HDDEELLK_01822 5.6e-200 oatA I Acyltransferase
HDDEELLK_01823 2.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDDEELLK_01824 1.9e-306 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDDEELLK_01825 2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDDEELLK_01828 1.5e-41 S Phosphoesterase
HDDEELLK_01829 5e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDDEELLK_01830 1.1e-60 yslB S Protein of unknown function (DUF2507)
HDDEELLK_01831 9.9e-41 trxA O Belongs to the thioredoxin family
HDDEELLK_01832 2.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDDEELLK_01833 1.2e-17 cvpA S Colicin V production protein
HDDEELLK_01834 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDDEELLK_01835 1.9e-33 yrzB S Belongs to the UPF0473 family
HDDEELLK_01836 5.2e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDDEELLK_01837 2.1e-36 yrzL S Belongs to the UPF0297 family
HDDEELLK_01838 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDDEELLK_01839 5.1e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDDEELLK_01840 1.6e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HDDEELLK_01841 7.5e-13
HDDEELLK_01842 8e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDDEELLK_01843 3.2e-66 yrjD S LUD domain
HDDEELLK_01844 1.1e-244 lutB C 4Fe-4S dicluster domain
HDDEELLK_01845 6.9e-117 lutA C Cysteine-rich domain
HDDEELLK_01846 2e-208 yfnA E Amino Acid
HDDEELLK_01848 4.3e-61 uspA T universal stress protein
HDDEELLK_01850 1.8e-12 yajC U Preprotein translocase
HDDEELLK_01851 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDDEELLK_01852 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDDEELLK_01853 2.8e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDDEELLK_01854 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDDEELLK_01855 8.4e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDDEELLK_01856 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDDEELLK_01857 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
HDDEELLK_01858 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDDEELLK_01859 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDDEELLK_01860 3.8e-64 ymfM S Helix-turn-helix domain
HDDEELLK_01861 2.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
HDDEELLK_01862 8.4e-150 ymfH S Peptidase M16
HDDEELLK_01863 5.3e-109 ymfF S Peptidase M16 inactive domain protein
HDDEELLK_01864 4.5e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
HDDEELLK_01865 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDDEELLK_01866 7.5e-99 rrmA 2.1.1.187 H Methyltransferase
HDDEELLK_01867 6.4e-61 ybaK J Aminoacyl-tRNA editing domain
HDDEELLK_01868 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDDEELLK_01869 8.1e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDDEELLK_01870 4.2e-21 cutC P Participates in the control of copper homeostasis
HDDEELLK_01871 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HDDEELLK_01872 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HDDEELLK_01873 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDDEELLK_01874 5.3e-68 ybbR S YbbR-like protein
HDDEELLK_01875 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDDEELLK_01876 2.4e-71 S Protein of unknown function (DUF1361)
HDDEELLK_01877 1.2e-115 murB 1.3.1.98 M Cell wall formation
HDDEELLK_01878 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
HDDEELLK_01879 2.5e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HDDEELLK_01880 1.3e-142 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HDDEELLK_01881 6.8e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDDEELLK_01882 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
HDDEELLK_01883 3.1e-42 yxjI
HDDEELLK_01884 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDDEELLK_01885 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDDEELLK_01886 2.8e-19 secG U Preprotein translocase
HDDEELLK_01887 9.2e-180 clcA P chloride
HDDEELLK_01888 6.7e-146 lmrP E Major Facilitator Superfamily
HDDEELLK_01889 1.8e-169 T PhoQ Sensor
HDDEELLK_01890 5e-104 K response regulator
HDDEELLK_01891 5e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDDEELLK_01892 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDDEELLK_01893 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDDEELLK_01894 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HDDEELLK_01895 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDDEELLK_01896 2.9e-137 cggR K Putative sugar-binding domain
HDDEELLK_01898 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDDEELLK_01899 1.8e-149 whiA K May be required for sporulation
HDDEELLK_01900 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HDDEELLK_01901 7.5e-126 rapZ S Displays ATPase and GTPase activities
HDDEELLK_01902 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
HDDEELLK_01903 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDDEELLK_01904 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDDEELLK_01905 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDDEELLK_01906 1.4e-272 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HDDEELLK_01907 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDDEELLK_01908 2.5e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDDEELLK_01909 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HDDEELLK_01910 4.1e-08 KT PspC domain protein
HDDEELLK_01911 1.2e-85 phoR 2.7.13.3 T Histidine kinase
HDDEELLK_01912 6e-86 K response regulator
HDDEELLK_01913 4.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HDDEELLK_01914 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDDEELLK_01915 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDDEELLK_01916 3.1e-95 yeaN P Major Facilitator Superfamily
HDDEELLK_01917 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDDEELLK_01918 1e-45 comFC S Competence protein
HDDEELLK_01919 5.4e-128 comFA L Helicase C-terminal domain protein
HDDEELLK_01920 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
HDDEELLK_01921 4.1e-296 ydaO E amino acid
HDDEELLK_01922 3.3e-269 aha1 P COG COG0474 Cation transport ATPase
HDDEELLK_01923 1.8e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDDEELLK_01924 1.8e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDDEELLK_01925 2.4e-33 S CAAX protease self-immunity
HDDEELLK_01926 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDDEELLK_01927 1.2e-253 uup S ABC transporter, ATP-binding protein
HDDEELLK_01928 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDDEELLK_01929 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HDDEELLK_01930 2.8e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HDDEELLK_01931 2.7e-140 ansA 3.5.1.1 EJ Asparaginase
HDDEELLK_01932 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
HDDEELLK_01933 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDDEELLK_01934 1.4e-40 yabA L Involved in initiation control of chromosome replication
HDDEELLK_01935 1e-83 holB 2.7.7.7 L DNA polymerase III
HDDEELLK_01936 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDDEELLK_01937 9.2e-29 yaaL S Protein of unknown function (DUF2508)
HDDEELLK_01938 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDDEELLK_01939 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDDEELLK_01940 1.5e-210 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDDEELLK_01941 4.8e-61 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDDEELLK_01942 1.1e-75 rsmC 2.1.1.172 J Methyltransferase
HDDEELLK_01943 1.2e-27 nrdH O Glutaredoxin
HDDEELLK_01944 4.8e-45 nrdI F NrdI Flavodoxin like
HDDEELLK_01945 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDDEELLK_01946 1.4e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDDEELLK_01947 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDDEELLK_01948 1.4e-54
HDDEELLK_01949 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDDEELLK_01950 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDDEELLK_01951 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDDEELLK_01952 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDDEELLK_01953 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
HDDEELLK_01954 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDDEELLK_01955 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDDEELLK_01956 7e-71 yacP S YacP-like NYN domain
HDDEELLK_01957 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDDEELLK_01958 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDDEELLK_01959 1.8e-206 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDDEELLK_01960 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDDEELLK_01961 8.2e-154 yacL S domain protein
HDDEELLK_01962 3.5e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDDEELLK_01963 3.1e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HDDEELLK_01964 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
HDDEELLK_01965 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
HDDEELLK_01966 1.4e-33 S Enterocin A Immunity
HDDEELLK_01967 8.3e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDDEELLK_01968 4.5e-129 mleP2 S Sodium Bile acid symporter family
HDDEELLK_01969 3.5e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDDEELLK_01971 2.3e-43 ydcK S Belongs to the SprT family
HDDEELLK_01972 3.3e-252 yhgF K Tex-like protein N-terminal domain protein
HDDEELLK_01973 6.8e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDDEELLK_01974 1.6e-242 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDDEELLK_01975 1.2e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDDEELLK_01976 6.4e-96 gntR1 K UbiC transcription regulator-associated domain protein
HDDEELLK_01977 1.2e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDDEELLK_01979 1.1e-07
HDDEELLK_01980 1.6e-197 dtpT U amino acid peptide transporter

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)