ORF_ID e_value Gene_name EC_number CAZy COGs Description
MEAKJJMH_00001 9e-30 yqkB S Belongs to the HesB IscA family
MEAKJJMH_00002 2.9e-43 yxkH G Polysaccharide deacetylase
MEAKJJMH_00003 5.4e-18 yxkH G Polysaccharide deacetylase
MEAKJJMH_00004 9.6e-09
MEAKJJMH_00005 1.7e-53 K LysR substrate binding domain
MEAKJJMH_00006 1.3e-121 MA20_14895 S Conserved hypothetical protein 698
MEAKJJMH_00007 1.1e-199 nupG F Nucleoside
MEAKJJMH_00008 3.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEAKJJMH_00009 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEAKJJMH_00010 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MEAKJJMH_00011 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEAKJJMH_00012 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEAKJJMH_00013 9e-20 yaaA S S4 domain protein YaaA
MEAKJJMH_00014 1.2e-152 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEAKJJMH_00015 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEAKJJMH_00016 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEAKJJMH_00017 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
MEAKJJMH_00018 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEAKJJMH_00019 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEAKJJMH_00020 4.8e-109 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MEAKJJMH_00021 7.3e-117 S Glycosyl transferase family 2
MEAKJJMH_00022 9.7e-64 D peptidase
MEAKJJMH_00023 0.0 asnB 6.3.5.4 E Asparagine synthase
MEAKJJMH_00024 3.3e-61 yiiE S Protein of unknown function (DUF1211)
MEAKJJMH_00025 3e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEAKJJMH_00026 3.7e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MEAKJJMH_00027 4.7e-17 yneR
MEAKJJMH_00028 5.7e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEAKJJMH_00029 8.4e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
MEAKJJMH_00030 3.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MEAKJJMH_00031 1.7e-152 mdtG EGP Major facilitator Superfamily
MEAKJJMH_00032 1.3e-14 yobS K transcriptional regulator
MEAKJJMH_00033 2.8e-109 glcU U sugar transport
MEAKJJMH_00034 3.4e-170 yjjP S Putative threonine/serine exporter
MEAKJJMH_00035 2.6e-68 2.3.1.178 J Acetyltransferase (GNAT) domain
MEAKJJMH_00036 1.7e-96 yicL EG EamA-like transporter family
MEAKJJMH_00039 5.6e-10 hol S Bacteriophage holin
MEAKJJMH_00040 1.5e-132 lys 3.5.1.104 M Glycosyl hydrolases family 25
MEAKJJMH_00041 1.7e-15
MEAKJJMH_00044 5.9e-87 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEAKJJMH_00045 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MEAKJJMH_00046 9.1e-43 yodB K Transcriptional regulator, HxlR family
MEAKJJMH_00047 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEAKJJMH_00048 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEAKJJMH_00049 5.1e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MEAKJJMH_00050 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
MEAKJJMH_00051 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEAKJJMH_00052 6.4e-12
MEAKJJMH_00053 2.3e-144 iunH2 3.2.2.1 F nucleoside hydrolase
MEAKJJMH_00054 7.6e-43 XK27_03960 S Protein of unknown function (DUF3013)
MEAKJJMH_00055 5.8e-118 prmA J Ribosomal protein L11 methyltransferase
MEAKJJMH_00056 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEAKJJMH_00057 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEAKJJMH_00058 3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEAKJJMH_00059 2.5e-56 3.1.3.18 J HAD-hyrolase-like
MEAKJJMH_00060 5.2e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEAKJJMH_00061 7.3e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEAKJJMH_00062 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEAKJJMH_00063 2.7e-204 pyrP F Permease
MEAKJJMH_00064 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MEAKJJMH_00065 2.2e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MEAKJJMH_00066 2e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEAKJJMH_00067 6.7e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEAKJJMH_00068 9.8e-135 K Transcriptional regulator
MEAKJJMH_00069 1.1e-143 ppaC 3.6.1.1 C inorganic pyrophosphatase
MEAKJJMH_00070 8.6e-115 glcR K DeoR C terminal sensor domain
MEAKJJMH_00071 1.7e-170 patA 2.6.1.1 E Aminotransferase
MEAKJJMH_00072 1.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MEAKJJMH_00074 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MEAKJJMH_00075 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MEAKJJMH_00076 1.4e-36 rnhA 3.1.26.4 L Ribonuclease HI
MEAKJJMH_00077 6.6e-23 S Family of unknown function (DUF5322)
MEAKJJMH_00078 7.7e-257 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MEAKJJMH_00079 1.1e-11
MEAKJJMH_00084 3.7e-16 V PFAM secretion protein HlyD family protein
MEAKJJMH_00086 1.1e-149 EGP Sugar (and other) transporter
MEAKJJMH_00087 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
MEAKJJMH_00088 4.8e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MEAKJJMH_00089 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MEAKJJMH_00090 3.9e-71 alkD L DNA alkylation repair enzyme
MEAKJJMH_00091 6.4e-136 EG EamA-like transporter family
MEAKJJMH_00092 5.2e-149 S Tetratricopeptide repeat protein
MEAKJJMH_00093 4.5e-204 hisS 6.1.1.21 J histidyl-tRNA synthetase
MEAKJJMH_00094 1.5e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MEAKJJMH_00095 2.7e-126 corA P CorA-like Mg2+ transporter protein
MEAKJJMH_00096 1.4e-160 nhaC C Na H antiporter NhaC
MEAKJJMH_00097 7.2e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MEAKJJMH_00098 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MEAKJJMH_00100 1.2e-91 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEAKJJMH_00101 1.7e-159 iscS 2.8.1.7 E Aminotransferase class V
MEAKJJMH_00102 3.7e-41 XK27_04120 S Putative amino acid metabolism
MEAKJJMH_00103 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEAKJJMH_00104 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEAKJJMH_00105 4.3e-15 S Protein of unknown function (DUF2929)
MEAKJJMH_00106 0.0 dnaE 2.7.7.7 L DNA polymerase
MEAKJJMH_00107 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MEAKJJMH_00108 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MEAKJJMH_00110 1e-39 ypaA S Protein of unknown function (DUF1304)
MEAKJJMH_00111 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEAKJJMH_00112 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEAKJJMH_00113 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEAKJJMH_00114 1.9e-202 FbpA K Fibronectin-binding protein
MEAKJJMH_00115 3.1e-40 K Transcriptional regulator
MEAKJJMH_00116 6.3e-117 degV S EDD domain protein, DegV family
MEAKJJMH_00117 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
MEAKJJMH_00118 2.7e-39 6.3.3.2 S ASCH
MEAKJJMH_00119 1.7e-187 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEAKJJMH_00120 1.1e-78 yjjH S Calcineurin-like phosphoesterase
MEAKJJMH_00121 1.8e-95 EG EamA-like transporter family
MEAKJJMH_00122 1.1e-84 natB CP ABC-type Na efflux pump, permease component
MEAKJJMH_00123 6.9e-111 natA S Domain of unknown function (DUF4162)
MEAKJJMH_00124 4.8e-23 K Acetyltransferase (GNAT) domain
MEAKJJMH_00126 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEAKJJMH_00127 4.5e-228 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MEAKJJMH_00128 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
MEAKJJMH_00129 3.7e-59 arsC 1.20.4.1 T Low molecular weight phosphatase family
MEAKJJMH_00130 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MEAKJJMH_00131 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEAKJJMH_00132 3.5e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
MEAKJJMH_00133 1.2e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEAKJJMH_00134 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
MEAKJJMH_00135 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
MEAKJJMH_00136 4.6e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEAKJJMH_00137 2.8e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MEAKJJMH_00138 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEAKJJMH_00139 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
MEAKJJMH_00140 2.6e-83 lytH 3.5.1.28 M Ami_3
MEAKJJMH_00141 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MEAKJJMH_00142 7.7e-12 M Lysin motif
MEAKJJMH_00143 1e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MEAKJJMH_00144 2.9e-60 ypbB 5.1.3.1 S Helix-turn-helix domain
MEAKJJMH_00145 2.9e-221 mntH P H( )-stimulated, divalent metal cation uptake system
MEAKJJMH_00146 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MEAKJJMH_00147 4.4e-57 ica2 GT2 M Glycosyl transferase family group 2
MEAKJJMH_00149 6.3e-44
MEAKJJMH_00150 1.6e-91 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEAKJJMH_00152 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEAKJJMH_00153 5.8e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEAKJJMH_00154 1.5e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MEAKJJMH_00155 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MEAKJJMH_00156 2.9e-109 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
MEAKJJMH_00157 8.2e-68 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEAKJJMH_00158 1.1e-62 3.1.21.3 V Type I restriction modification DNA specificity domain
MEAKJJMH_00159 4.3e-84 L Belongs to the 'phage' integrase family
MEAKJJMH_00160 2.8e-11 L Belongs to the 'phage' integrase family
MEAKJJMH_00161 4.7e-45 3.1.21.3 V Type I restriction modification DNA specificity domain protein
MEAKJJMH_00162 2.7e-211 hsdM 2.1.1.72 V type I restriction-modification system
MEAKJJMH_00163 1.5e-37 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MEAKJJMH_00164 1.3e-275 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MEAKJJMH_00166 3e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
MEAKJJMH_00167 5.7e-57 3.6.1.27 I Acid phosphatase homologues
MEAKJJMH_00168 1.3e-68 maa 2.3.1.79 S Maltose acetyltransferase
MEAKJJMH_00169 7e-72 2.3.1.178 M GNAT acetyltransferase
MEAKJJMH_00171 4.6e-196 ade 3.5.4.2 F Adenine deaminase C-terminal domain
MEAKJJMH_00172 1.5e-63 ypsA S Belongs to the UPF0398 family
MEAKJJMH_00173 1.3e-188 nhaC C Na H antiporter NhaC
MEAKJJMH_00174 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEAKJJMH_00175 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MEAKJJMH_00176 2.8e-112 xerD D recombinase XerD
MEAKJJMH_00177 1.1e-124 cvfB S S1 domain
MEAKJJMH_00178 1.6e-50 yeaL S Protein of unknown function (DUF441)
MEAKJJMH_00179 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEAKJJMH_00180 4.9e-99 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEAKJJMH_00181 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEAKJJMH_00182 5.9e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEAKJJMH_00183 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEAKJJMH_00184 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MEAKJJMH_00185 4.5e-78 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MEAKJJMH_00186 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MEAKJJMH_00187 7.8e-179 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MEAKJJMH_00188 1.2e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MEAKJJMH_00189 3.1e-71
MEAKJJMH_00191 3.7e-12
MEAKJJMH_00192 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MEAKJJMH_00193 1e-27 ysxB J Cysteine protease Prp
MEAKJJMH_00194 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
MEAKJJMH_00198 2.2e-08 S Protein of unknown function (DUF2922)
MEAKJJMH_00200 1.3e-16 K DNA-templated transcription, initiation
MEAKJJMH_00202 8.1e-65 H Methyltransferase domain
MEAKJJMH_00203 1e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
MEAKJJMH_00204 1.9e-41 wecD M Acetyltransferase (GNAT) family
MEAKJJMH_00206 6.2e-26 ybl78 L Conserved phage C-terminus (Phg_2220_C)
MEAKJJMH_00207 6.7e-18 S Protein of unknown function (DUF1211)
MEAKJJMH_00208 1.1e-14 S Protein of unknown function (DUF1211)
MEAKJJMH_00210 6.6e-86 1.1.1.1 C Zinc-binding dehydrogenase
MEAKJJMH_00211 2.2e-32 S CHY zinc finger
MEAKJJMH_00212 9.5e-40 K Transcriptional regulator
MEAKJJMH_00213 2.7e-55 qorB 1.6.5.2 GM NmrA-like family
MEAKJJMH_00216 4.5e-64 M Glycosyl transferases group 1
MEAKJJMH_00217 2.6e-180 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MEAKJJMH_00218 1.4e-145 lspL 5.1.3.6 GM RmlD substrate binding domain
MEAKJJMH_00219 1.1e-105 cps2I S Psort location CytoplasmicMembrane, score
MEAKJJMH_00220 3.5e-61 cps1B GT2,GT4 M Glycosyl transferases group 1
MEAKJJMH_00221 2.2e-114 S Glycosyltransferase WbsX
MEAKJJMH_00222 2.1e-08 wzy S EpsG family
MEAKJJMH_00223 1.6e-51 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
MEAKJJMH_00224 1.7e-52 M Glycosyltransferase Family 4
MEAKJJMH_00226 2.4e-76 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
MEAKJJMH_00227 6.8e-79 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
MEAKJJMH_00228 3.9e-124 2.4.1.52 GT4 M Glycosyl transferases group 1
MEAKJJMH_00229 6.5e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
MEAKJJMH_00230 8e-77 epsL M Bacterial sugar transferase
MEAKJJMH_00231 3.4e-166 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
MEAKJJMH_00232 1.6e-71 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 M CoA-binding domain
MEAKJJMH_00233 1.5e-132 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MEAKJJMH_00234 4e-48 cps4C M Chain length determinant protein
MEAKJJMH_00235 1e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MEAKJJMH_00236 3.8e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MEAKJJMH_00237 8.1e-81
MEAKJJMH_00238 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MEAKJJMH_00239 3.5e-114 yitU 3.1.3.104 S hydrolase
MEAKJJMH_00240 4.7e-59 speG J Acetyltransferase (GNAT) domain
MEAKJJMH_00241 8.8e-192 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEAKJJMH_00242 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MEAKJJMH_00243 1.3e-204 pipD E Dipeptidase
MEAKJJMH_00244 2.8e-43
MEAKJJMH_00245 2.6e-64 K helix_turn_helix, arabinose operon control protein
MEAKJJMH_00246 2e-53 S Membrane
MEAKJJMH_00247 0.0 rafA 3.2.1.22 G alpha-galactosidase
MEAKJJMH_00248 3.6e-60 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
MEAKJJMH_00249 1.9e-303 L Helicase C-terminal domain protein
MEAKJJMH_00250 1.1e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MEAKJJMH_00251 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MEAKJJMH_00252 1.4e-113 2.7.7.65 T diguanylate cyclase activity
MEAKJJMH_00253 0.0 ydaN S Bacterial cellulose synthase subunit
MEAKJJMH_00254 6.9e-202 ydaM M Glycosyl transferase family group 2
MEAKJJMH_00255 9.1e-156 S Protein conserved in bacteria
MEAKJJMH_00256 1.5e-36 S Protein conserved in bacteria
MEAKJJMH_00257 4.2e-182
MEAKJJMH_00258 2.8e-127 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
MEAKJJMH_00259 6.4e-32 2.7.7.65 T GGDEF domain
MEAKJJMH_00260 7.3e-146 pbuO_1 S Permease family
MEAKJJMH_00261 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
MEAKJJMH_00262 1.5e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MEAKJJMH_00263 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MEAKJJMH_00264 6.7e-219 cydD CO ABC transporter transmembrane region
MEAKJJMH_00265 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MEAKJJMH_00266 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MEAKJJMH_00267 2.1e-194 cydA 1.10.3.14 C ubiquinol oxidase
MEAKJJMH_00268 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
MEAKJJMH_00269 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
MEAKJJMH_00270 5e-19 glpE P Rhodanese Homology Domain
MEAKJJMH_00271 4.2e-49 lytE M LysM domain protein
MEAKJJMH_00272 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
MEAKJJMH_00273 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
MEAKJJMH_00275 4.4e-74 draG O ADP-ribosylglycohydrolase
MEAKJJMH_00276 4.8e-26 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEAKJJMH_00277 2.2e-49 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEAKJJMH_00279 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEAKJJMH_00280 8.6e-62 divIVA D DivIVA domain protein
MEAKJJMH_00281 1.7e-81 ylmH S S4 domain protein
MEAKJJMH_00282 3e-19 yggT S YGGT family
MEAKJJMH_00283 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEAKJJMH_00284 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEAKJJMH_00285 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEAKJJMH_00286 1.6e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MEAKJJMH_00287 6.8e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEAKJJMH_00288 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEAKJJMH_00289 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEAKJJMH_00290 6.9e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
MEAKJJMH_00291 2.5e-11 ftsL D cell division protein FtsL
MEAKJJMH_00292 6.7e-141 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEAKJJMH_00293 5.2e-64 mraZ K Belongs to the MraZ family
MEAKJJMH_00294 2.2e-07 S Protein of unknown function (DUF3397)
MEAKJJMH_00295 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MEAKJJMH_00297 9.8e-100 D Alpha beta
MEAKJJMH_00298 3.7e-109 aatB ET ABC transporter substrate-binding protein
MEAKJJMH_00299 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEAKJJMH_00300 1.9e-94 glnP P ABC transporter permease
MEAKJJMH_00301 1.8e-126 minD D Belongs to the ParA family
MEAKJJMH_00302 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MEAKJJMH_00303 1.5e-54 mreD M rod shape-determining protein MreD
MEAKJJMH_00304 2.1e-88 mreC M Involved in formation and maintenance of cell shape
MEAKJJMH_00305 3.6e-156 mreB D cell shape determining protein MreB
MEAKJJMH_00306 4.5e-21 K Cold shock
MEAKJJMH_00307 6.2e-80 radC L DNA repair protein
MEAKJJMH_00308 4e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MEAKJJMH_00309 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEAKJJMH_00310 1.2e-195 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEAKJJMH_00311 3.8e-162 iscS2 2.8.1.7 E Aminotransferase class V
MEAKJJMH_00312 4.4e-175 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MEAKJJMH_00313 3.5e-55 ytsP 1.8.4.14 T GAF domain-containing protein
MEAKJJMH_00314 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEAKJJMH_00315 2e-24 yueI S Protein of unknown function (DUF1694)
MEAKJJMH_00316 2e-188 rarA L recombination factor protein RarA
MEAKJJMH_00318 9.3e-73 usp6 T universal stress protein
MEAKJJMH_00319 1.5e-196 pepF E Oligopeptidase F
MEAKJJMH_00320 2.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MEAKJJMH_00321 3.7e-178 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MEAKJJMH_00322 1.2e-138 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
MEAKJJMH_00323 5e-59 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MEAKJJMH_00324 2.8e-24 relB L RelB antitoxin
MEAKJJMH_00325 2.1e-30 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MEAKJJMH_00326 7.5e-173 S Putative peptidoglycan binding domain
MEAKJJMH_00327 1.2e-31 K Transcriptional regulator, MarR family
MEAKJJMH_00328 3.6e-217 XK27_09600 V ABC transporter, ATP-binding protein
MEAKJJMH_00329 3.4e-242 V ABC transporter transmembrane region
MEAKJJMH_00330 1.3e-10 yxeH S hydrolase
MEAKJJMH_00331 2.8e-85 yxeH S hydrolase
MEAKJJMH_00332 9e-114 K response regulator
MEAKJJMH_00333 9.6e-272 vicK 2.7.13.3 T Histidine kinase
MEAKJJMH_00334 4.6e-103 yycH S YycH protein
MEAKJJMH_00335 5.6e-80 yycI S YycH protein
MEAKJJMH_00336 6.8e-30 yyaQ S YjbR
MEAKJJMH_00337 3.2e-115 vicX 3.1.26.11 S domain protein
MEAKJJMH_00338 2.8e-145 htrA 3.4.21.107 O serine protease
MEAKJJMH_00339 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEAKJJMH_00340 5.7e-40 1.6.5.2 GM NAD(P)H-binding
MEAKJJMH_00341 3.3e-25 K MarR family transcriptional regulator
MEAKJJMH_00342 3.5e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
MEAKJJMH_00343 4.3e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MEAKJJMH_00345 3.6e-207 G glycerol-3-phosphate transporter
MEAKJJMH_00346 9.4e-137 S interspecies interaction between organisms
MEAKJJMH_00347 1.2e-17 ebh 2.1.1.80, 3.1.1.61 D interspecies interaction between organisms
MEAKJJMH_00348 1.9e-53 tag 3.2.2.20 L glycosylase
MEAKJJMH_00349 2.2e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MEAKJJMH_00350 3.5e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MEAKJJMH_00352 1.6e-52 yviA S Protein of unknown function (DUF421)
MEAKJJMH_00353 1.8e-27 S Protein of unknown function (DUF3290)
MEAKJJMH_00354 6.8e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
MEAKJJMH_00355 1.2e-296 S membrane
MEAKJJMH_00356 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEAKJJMH_00357 1.5e-218 recJ L Single-stranded-DNA-specific exonuclease RecJ
MEAKJJMH_00358 5.8e-101 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MEAKJJMH_00359 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEAKJJMH_00361 5.4e-16
MEAKJJMH_00362 5.6e-200 oatA I Acyltransferase
MEAKJJMH_00363 6.3e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEAKJJMH_00364 5.6e-306 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEAKJJMH_00365 2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAKJJMH_00368 1.5e-41 S Phosphoesterase
MEAKJJMH_00369 5e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEAKJJMH_00370 1.1e-60 yslB S Protein of unknown function (DUF2507)
MEAKJJMH_00371 9.9e-41 trxA O Belongs to the thioredoxin family
MEAKJJMH_00372 2.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEAKJJMH_00373 7.5e-15 cvpA S Colicin V production protein
MEAKJJMH_00374 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MEAKJJMH_00375 1.9e-33 yrzB S Belongs to the UPF0473 family
MEAKJJMH_00376 1e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEAKJJMH_00377 2.1e-36 yrzL S Belongs to the UPF0297 family
MEAKJJMH_00378 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEAKJJMH_00379 1.5e-186 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MEAKJJMH_00380 4.7e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MEAKJJMH_00381 7.5e-13
MEAKJJMH_00382 8e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEAKJJMH_00383 1.1e-66 yrjD S LUD domain
MEAKJJMH_00384 3.6e-245 lutB C 4Fe-4S dicluster domain
MEAKJJMH_00385 1.5e-116 lutA C Cysteine-rich domain
MEAKJJMH_00386 2e-208 yfnA E Amino Acid
MEAKJJMH_00388 4.3e-61 uspA T universal stress protein
MEAKJJMH_00390 1.4e-12 yajC U Preprotein translocase
MEAKJJMH_00391 2.3e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEAKJJMH_00392 2.3e-182 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MEAKJJMH_00393 2.8e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEAKJJMH_00394 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEAKJJMH_00395 1.3e-226 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEAKJJMH_00396 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEAKJJMH_00397 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
MEAKJJMH_00398 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEAKJJMH_00399 7.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEAKJJMH_00400 1.5e-63 ymfM S Helix-turn-helix domain
MEAKJJMH_00401 4.9e-91 IQ Enoyl-(Acyl carrier protein) reductase
MEAKJJMH_00402 6.4e-150 ymfH S Peptidase M16
MEAKJJMH_00403 1.2e-108 ymfF S Peptidase M16 inactive domain protein
MEAKJJMH_00404 4.5e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
MEAKJJMH_00405 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEAKJJMH_00406 1.3e-98 rrmA 2.1.1.187 H Methyltransferase
MEAKJJMH_00407 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
MEAKJJMH_00408 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEAKJJMH_00409 1.4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEAKJJMH_00410 3.2e-21 cutC P Participates in the control of copper homeostasis
MEAKJJMH_00411 2e-130 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MEAKJJMH_00412 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MEAKJJMH_00413 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEAKJJMH_00414 5.3e-68 ybbR S YbbR-like protein
MEAKJJMH_00415 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEAKJJMH_00416 2.4e-71 S Protein of unknown function (DUF1361)
MEAKJJMH_00417 4.6e-115 murB 1.3.1.98 M Cell wall formation
MEAKJJMH_00418 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
MEAKJJMH_00419 3.2e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MEAKJJMH_00420 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MEAKJJMH_00421 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEAKJJMH_00422 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
MEAKJJMH_00423 4.1e-42 yxjI
MEAKJJMH_00424 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEAKJJMH_00425 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEAKJJMH_00426 2.8e-19 secG U Preprotein translocase
MEAKJJMH_00427 4.6e-179 clcA P chloride
MEAKJJMH_00428 6.7e-146 lmrP E Major Facilitator Superfamily
MEAKJJMH_00429 1.8e-169 T PhoQ Sensor
MEAKJJMH_00430 1.9e-103 K response regulator
MEAKJJMH_00431 1.3e-129 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEAKJJMH_00432 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEAKJJMH_00433 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEAKJJMH_00434 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MEAKJJMH_00435 7.9e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEAKJJMH_00436 6.4e-137 cggR K Putative sugar-binding domain
MEAKJJMH_00438 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEAKJJMH_00439 1.8e-149 whiA K May be required for sporulation
MEAKJJMH_00440 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MEAKJJMH_00441 7.5e-126 rapZ S Displays ATPase and GTPase activities
MEAKJJMH_00442 5e-79 ylbE GM NAD dependent epimerase dehydratase family protein
MEAKJJMH_00443 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEAKJJMH_00444 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEAKJJMH_00445 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEAKJJMH_00446 1.5e-271 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MEAKJJMH_00447 1.9e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEAKJJMH_00448 9.6e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MEAKJJMH_00449 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MEAKJJMH_00450 3.2e-08 KT PspC domain protein
MEAKJJMH_00451 4.5e-85 phoR 2.7.13.3 T Histidine kinase
MEAKJJMH_00452 4.6e-86 K response regulator
MEAKJJMH_00453 4.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
MEAKJJMH_00454 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEAKJJMH_00455 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEAKJJMH_00456 1.7e-96 yeaN P Major Facilitator Superfamily
MEAKJJMH_00457 7.8e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEAKJJMH_00458 1e-45 comFC S Competence protein
MEAKJJMH_00459 4.2e-128 comFA L Helicase C-terminal domain protein
MEAKJJMH_00460 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
MEAKJJMH_00461 4.1e-296 ydaO E amino acid
MEAKJJMH_00462 1.3e-268 aha1 P COG COG0474 Cation transport ATPase
MEAKJJMH_00463 1.4e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEAKJJMH_00464 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEAKJJMH_00465 5.3e-33 S CAAX protease self-immunity
MEAKJJMH_00466 1.3e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEAKJJMH_00467 1.9e-254 uup S ABC transporter, ATP-binding protein
MEAKJJMH_00468 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEAKJJMH_00469 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MEAKJJMH_00470 2.8e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MEAKJJMH_00471 1.6e-140 ansA 3.5.1.1 EJ Asparaginase
MEAKJJMH_00472 2.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
MEAKJJMH_00473 2.1e-91 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEAKJJMH_00474 1.4e-40 yabA L Involved in initiation control of chromosome replication
MEAKJJMH_00475 2.3e-83 holB 2.7.7.7 L DNA polymerase III
MEAKJJMH_00476 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEAKJJMH_00477 9.2e-29 yaaL S Protein of unknown function (DUF2508)
MEAKJJMH_00478 8.4e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEAKJJMH_00479 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MEAKJJMH_00480 1e-211 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEAKJJMH_00481 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEAKJJMH_00482 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
MEAKJJMH_00483 2.7e-27 nrdH O Glutaredoxin
MEAKJJMH_00484 4.8e-45 nrdI F NrdI Flavodoxin like
MEAKJJMH_00485 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEAKJJMH_00486 5.2e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEAKJJMH_00487 2.7e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEAKJJMH_00488 4.7e-55
MEAKJJMH_00489 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEAKJJMH_00490 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEAKJJMH_00491 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEAKJJMH_00492 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEAKJJMH_00493 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
MEAKJJMH_00494 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEAKJJMH_00495 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MEAKJJMH_00496 7e-71 yacP S YacP-like NYN domain
MEAKJJMH_00497 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEAKJJMH_00498 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MEAKJJMH_00499 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEAKJJMH_00500 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEAKJJMH_00501 8.2e-154 yacL S domain protein
MEAKJJMH_00502 1.6e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEAKJJMH_00503 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MEAKJJMH_00504 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
MEAKJJMH_00505 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
MEAKJJMH_00506 1e-33 S Enterocin A Immunity
MEAKJJMH_00507 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEAKJJMH_00508 5.9e-129 mleP2 S Sodium Bile acid symporter family
MEAKJJMH_00509 1e-115 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEAKJJMH_00511 3.6e-44 ydcK S Belongs to the SprT family
MEAKJJMH_00512 5.9e-249 yhgF K Tex-like protein N-terminal domain protein
MEAKJJMH_00513 2.3e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MEAKJJMH_00514 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEAKJJMH_00515 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MEAKJJMH_00516 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
MEAKJJMH_00517 1.2e-88 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEAKJJMH_00518 1.5e-08 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MEAKJJMH_00520 9.8e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEAKJJMH_00521 8.4e-119 ytbE S reductase
MEAKJJMH_00522 4.2e-43 ytcD K HxlR-like helix-turn-helix
MEAKJJMH_00523 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
MEAKJJMH_00524 9.3e-42 ybbL S ABC transporter
MEAKJJMH_00525 2.5e-12 ybbL S ABC transporter, ATP-binding protein
MEAKJJMH_00526 2.4e-162 oxlT P Major Facilitator Superfamily
MEAKJJMH_00527 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEAKJJMH_00528 4.5e-46 S Short repeat of unknown function (DUF308)
MEAKJJMH_00529 3.4e-29 tetR K Transcriptional regulator C-terminal region
MEAKJJMH_00530 1.2e-150 yfeX P Peroxidase
MEAKJJMH_00531 2.5e-16 S Protein of unknown function (DUF3021)
MEAKJJMH_00532 4.5e-39 K LytTr DNA-binding domain
MEAKJJMH_00533 9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MEAKJJMH_00534 4.2e-208 mmuP E amino acid
MEAKJJMH_00535 9.2e-16 psiE S Phosphate-starvation-inducible E
MEAKJJMH_00536 2.2e-155 oppF P Belongs to the ABC transporter superfamily
MEAKJJMH_00537 1.3e-180 oppD P Belongs to the ABC transporter superfamily
MEAKJJMH_00538 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEAKJJMH_00539 4.6e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEAKJJMH_00540 1.4e-202 oppA E ABC transporter, substratebinding protein
MEAKJJMH_00541 2.3e-217 yifK E Amino acid permease
MEAKJJMH_00542 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEAKJJMH_00543 1.1e-56 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
MEAKJJMH_00544 1.4e-65 pgm3 G phosphoglycerate mutase family
MEAKJJMH_00545 2.1e-250 ctpA 3.6.3.54 P P-type ATPase
MEAKJJMH_00546 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MEAKJJMH_00547 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MEAKJJMH_00548 2.8e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MEAKJJMH_00549 1.2e-21 K transcriptional regulator
MEAKJJMH_00550 5e-77 hchA S intracellular protease amidase
MEAKJJMH_00551 4.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MEAKJJMH_00552 1.8e-112 lacI3 K helix_turn _helix lactose operon repressor
MEAKJJMH_00553 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
MEAKJJMH_00554 7.5e-39 2.7.1.191 G PTS system fructose IIA component
MEAKJJMH_00555 3.2e-123 G PTS system mannose/fructose/sorbose family IID component
MEAKJJMH_00556 4.4e-101 G PTS system sorbose-specific iic component
MEAKJJMH_00557 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
MEAKJJMH_00558 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MEAKJJMH_00559 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MEAKJJMH_00560 9.9e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
MEAKJJMH_00561 1.4e-116 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
MEAKJJMH_00562 9e-198 1.3.5.4 C FMN_bind
MEAKJJMH_00563 3.7e-56 3.1.3.48 K Transcriptional regulator
MEAKJJMH_00564 5.5e-160 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MEAKJJMH_00565 5.3e-197 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MEAKJJMH_00566 4.9e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MEAKJJMH_00567 1.1e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
MEAKJJMH_00568 2.3e-99 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MEAKJJMH_00569 2.5e-82 S Belongs to the UPF0246 family
MEAKJJMH_00570 1.9e-10 S CAAX protease self-immunity
MEAKJJMH_00571 1.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
MEAKJJMH_00572 1.5e-156 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEAKJJMH_00574 9.6e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEAKJJMH_00575 2e-63 C FMN binding
MEAKJJMH_00576 4.7e-207 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MEAKJJMH_00577 1.7e-54 rplI J Binds to the 23S rRNA
MEAKJJMH_00578 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MEAKJJMH_00579 6.1e-07
MEAKJJMH_00583 1.9e-59 rny D peptidase
MEAKJJMH_00584 1.3e-58 S Phage tail protein
MEAKJJMH_00585 6.5e-106 M Phage tail tape measure protein TP901
MEAKJJMH_00586 1.1e-38 S Bacteriophage Gp15 protein
MEAKJJMH_00588 2.6e-38 N domain, Protein
MEAKJJMH_00589 7.6e-17 S Minor capsid protein from bacteriophage
MEAKJJMH_00590 3e-15 S Minor capsid protein
MEAKJJMH_00591 4.4e-29 S Minor capsid protein
MEAKJJMH_00592 8.9e-15
MEAKJJMH_00593 2.3e-98 S T=7 icosahedral viral capsid
MEAKJJMH_00601 3.9e-16
MEAKJJMH_00602 5.7e-44 S magnesium ion binding
MEAKJJMH_00603 0.0 L Primase C terminal 2 (PriCT-2)
MEAKJJMH_00604 1.2e-262 L Helicase C-terminal domain protein
MEAKJJMH_00605 1.6e-81
MEAKJJMH_00606 7.4e-39
MEAKJJMH_00607 1.3e-50
MEAKJJMH_00608 5.4e-102 S AAA domain
MEAKJJMH_00609 6.6e-163 D AAA domain
MEAKJJMH_00614 2.4e-14
MEAKJJMH_00615 1.1e-105 K ORF6N domain
MEAKJJMH_00616 1.2e-10 K Helix-turn-helix XRE-family like proteins
MEAKJJMH_00619 3.3e-29 3.4.21.88 K Helix-turn-helix domain
MEAKJJMH_00620 1.1e-29 E Zn peptidase
MEAKJJMH_00621 4e-28 S Domain of unknown function (DUF4352)
MEAKJJMH_00622 1.9e-30
MEAKJJMH_00623 2.3e-107 S Protein of unknown function (DUF3644)
MEAKJJMH_00624 4.8e-80 sip L Belongs to the 'phage' integrase family
MEAKJJMH_00625 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MEAKJJMH_00631 1.1e-07
MEAKJJMH_00632 1.6e-197 dtpT U amino acid peptide transporter
MEAKJJMH_00633 1.9e-92 yihY S Belongs to the UPF0761 family
MEAKJJMH_00634 4.7e-12 mltD CBM50 M Lysin motif
MEAKJJMH_00635 2.1e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MEAKJJMH_00636 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
MEAKJJMH_00637 5.1e-54 fld C Flavodoxin
MEAKJJMH_00638 3.1e-50 gtcA S Teichoic acid glycosylation protein
MEAKJJMH_00639 0.0 S Bacterial membrane protein YfhO
MEAKJJMH_00640 2.2e-118 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
MEAKJJMH_00641 1.7e-122 S Sulfite exporter TauE/SafE
MEAKJJMH_00642 1.1e-70 K Sugar-specific transcriptional regulator TrmB
MEAKJJMH_00643 1.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MEAKJJMH_00644 3.9e-181 pepS E Thermophilic metalloprotease (M29)
MEAKJJMH_00645 5.7e-265 E Amino acid permease
MEAKJJMH_00646 2e-83 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MEAKJJMH_00647 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MEAKJJMH_00648 2.6e-79 galM 5.1.3.3 G Aldose 1-epimerase
MEAKJJMH_00649 4.3e-213 malT G Transporter, major facilitator family protein
MEAKJJMH_00650 4.2e-101 malR K Transcriptional regulator, LacI family
MEAKJJMH_00651 2.3e-279 kup P Transport of potassium into the cell
MEAKJJMH_00653 2e-20 S Domain of unknown function (DUF3284)
MEAKJJMH_00654 5.2e-160 yfmL L DEAD DEAH box helicase
MEAKJJMH_00655 7e-128 mocA S Oxidoreductase
MEAKJJMH_00656 2e-24 S Domain of unknown function (DUF4828)
MEAKJJMH_00657 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
MEAKJJMH_00658 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MEAKJJMH_00659 1.4e-193 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
MEAKJJMH_00660 3.4e-126 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
MEAKJJMH_00661 4.2e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MEAKJJMH_00662 6.2e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MEAKJJMH_00663 2.5e-221 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MEAKJJMH_00664 1.1e-41 O ADP-ribosylglycohydrolase
MEAKJJMH_00665 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MEAKJJMH_00666 2.9e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MEAKJJMH_00667 1.3e-34 K GNAT family
MEAKJJMH_00668 1.7e-40
MEAKJJMH_00670 5.5e-160 mgtE P Acts as a magnesium transporter
MEAKJJMH_00671 1.9e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MEAKJJMH_00672 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEAKJJMH_00673 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
MEAKJJMH_00674 3.9e-258 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MEAKJJMH_00675 9.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MEAKJJMH_00676 9.7e-194 pbuX F xanthine permease
MEAKJJMH_00677 9.7e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEAKJJMH_00678 3.1e-60 acmC 3.2.1.96 NU mannosyl-glycoprotein
MEAKJJMH_00679 9.4e-64 S ECF transporter, substrate-specific component
MEAKJJMH_00680 3.3e-127 mleP S Sodium Bile acid symporter family
MEAKJJMH_00681 4.4e-249 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MEAKJJMH_00682 1.4e-71 mleR K LysR family
MEAKJJMH_00683 1.1e-56 K transcriptional
MEAKJJMH_00684 1.5e-41 K Bacterial regulatory proteins, tetR family
MEAKJJMH_00685 4e-59 T Belongs to the universal stress protein A family
MEAKJJMH_00686 1.2e-44 K Copper transport repressor CopY TcrY
MEAKJJMH_00687 1e-62 3.2.1.18 GH33 M Rib/alpha-like repeat
MEAKJJMH_00688 2.1e-157 3.2.1.18 GH33 M Rib/alpha-like repeat
MEAKJJMH_00690 7.1e-95 ypuA S Protein of unknown function (DUF1002)
MEAKJJMH_00691 2.1e-58 dedA 3.1.3.1 S SNARE associated Golgi protein
MEAKJJMH_00692 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEAKJJMH_00693 2.6e-18 yncA 2.3.1.79 S Maltose acetyltransferase
MEAKJJMH_00694 1.5e-205 yflS P Sodium:sulfate symporter transmembrane region
MEAKJJMH_00695 7.2e-200 frdC 1.3.5.4 C FAD binding domain
MEAKJJMH_00696 1.9e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MEAKJJMH_00697 2e-14 ybaN S Protein of unknown function (DUF454)
MEAKJJMH_00698 6.3e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MEAKJJMH_00699 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEAKJJMH_00700 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEAKJJMH_00701 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MEAKJJMH_00702 3.3e-71 ywlG S Belongs to the UPF0340 family
MEAKJJMH_00703 3.3e-158 C Oxidoreductase
MEAKJJMH_00704 8.6e-176 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
MEAKJJMH_00706 2.2e-146 3.6.4.12 L UvrD/REP helicase N-terminal domain
MEAKJJMH_00707 1.8e-11 L AAA ATPase domain
MEAKJJMH_00708 3.1e-26 L AAA ATPase domain
MEAKJJMH_00709 0.0 hsdR 3.1.21.3 L COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
MEAKJJMH_00710 1.3e-75 3.1.21.3 V Type I restriction modification DNA specificity domain
MEAKJJMH_00711 0.0 2.1.1.72 V type I restriction-modification system
MEAKJJMH_00712 3.9e-19
MEAKJJMH_00713 3.7e-122 L Mrr N-terminal domain
MEAKJJMH_00714 2.6e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEAKJJMH_00715 3.4e-146 yegS 2.7.1.107 G Lipid kinase
MEAKJJMH_00716 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEAKJJMH_00717 1.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEAKJJMH_00718 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEAKJJMH_00719 1.6e-160 camS S sex pheromone
MEAKJJMH_00720 1.5e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEAKJJMH_00721 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MEAKJJMH_00723 3.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEAKJJMH_00727 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MEAKJJMH_00728 6.1e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEAKJJMH_00729 2.4e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MEAKJJMH_00730 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEAKJJMH_00731 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MEAKJJMH_00732 4.2e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEAKJJMH_00733 1.1e-40 yabR J RNA binding
MEAKJJMH_00734 1e-21 divIC D Septum formation initiator
MEAKJJMH_00735 3.6e-31 yabO J S4 domain protein
MEAKJJMH_00736 7.3e-140 yabM S Polysaccharide biosynthesis protein
MEAKJJMH_00737 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEAKJJMH_00738 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEAKJJMH_00739 6.2e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MEAKJJMH_00740 1.6e-85 S (CBS) domain
MEAKJJMH_00741 1.4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEAKJJMH_00742 9.4e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEAKJJMH_00743 7.2e-53 perR P Belongs to the Fur family
MEAKJJMH_00744 2.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
MEAKJJMH_00745 2e-93 sbcC L Putative exonuclease SbcCD, C subunit
MEAKJJMH_00746 2.2e-114 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MEAKJJMH_00747 8.6e-38 M LysM domain protein
MEAKJJMH_00748 1.5e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MEAKJJMH_00749 2e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MEAKJJMH_00750 2e-35 ygfC K Bacterial regulatory proteins, tetR family
MEAKJJMH_00751 2.9e-100 hrtB V ABC transporter permease
MEAKJJMH_00752 1.5e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MEAKJJMH_00753 2.5e-69 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MEAKJJMH_00754 0.0 helD 3.6.4.12 L DNA helicase
MEAKJJMH_00755 4e-246 yjbQ P TrkA C-terminal domain protein
MEAKJJMH_00756 5.7e-26
MEAKJJMH_00757 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
MEAKJJMH_00758 2.7e-76 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEAKJJMH_00759 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEAKJJMH_00760 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEAKJJMH_00761 5.7e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEAKJJMH_00762 1e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEAKJJMH_00763 4.8e-53 rplQ J Ribosomal protein L17
MEAKJJMH_00764 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEAKJJMH_00765 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEAKJJMH_00766 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEAKJJMH_00767 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MEAKJJMH_00768 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEAKJJMH_00769 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEAKJJMH_00770 2.2e-206 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEAKJJMH_00771 1e-67 rplO J Binds to the 23S rRNA
MEAKJJMH_00772 2.1e-22 rpmD J Ribosomal protein L30
MEAKJJMH_00773 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEAKJJMH_00774 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEAKJJMH_00775 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEAKJJMH_00776 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEAKJJMH_00777 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEAKJJMH_00778 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEAKJJMH_00779 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEAKJJMH_00780 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEAKJJMH_00781 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEAKJJMH_00782 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
MEAKJJMH_00783 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEAKJJMH_00784 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEAKJJMH_00785 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEAKJJMH_00786 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEAKJJMH_00787 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEAKJJMH_00788 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEAKJJMH_00789 1e-100 rplD J Forms part of the polypeptide exit tunnel
MEAKJJMH_00790 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEAKJJMH_00791 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MEAKJJMH_00792 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEAKJJMH_00793 2.2e-79 K rpiR family
MEAKJJMH_00794 1.2e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MEAKJJMH_00795 7.2e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MEAKJJMH_00796 8.4e-21 K Acetyltransferase (GNAT) domain
MEAKJJMH_00797 2.9e-182 steT E amino acid
MEAKJJMH_00798 9.6e-78 glnP P ABC transporter permease
MEAKJJMH_00799 1.2e-85 gluC P ABC transporter permease
MEAKJJMH_00800 2.5e-99 glnH ET ABC transporter
MEAKJJMH_00801 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEAKJJMH_00802 3.9e-08
MEAKJJMH_00803 2.9e-98
MEAKJJMH_00804 3.1e-09 3.2.1.14 GH18
MEAKJJMH_00805 3.2e-53 zur P Belongs to the Fur family
MEAKJJMH_00806 3.7e-212 yfnA E Amino Acid
MEAKJJMH_00807 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEAKJJMH_00808 0.0 L Helicase C-terminal domain protein
MEAKJJMH_00809 1.6e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
MEAKJJMH_00810 7.9e-180 yhdP S Transporter associated domain
MEAKJJMH_00811 1.3e-23
MEAKJJMH_00812 9.6e-76 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEAKJJMH_00813 9.6e-132 bacI V MacB-like periplasmic core domain
MEAKJJMH_00814 4.8e-96 V ABC transporter
MEAKJJMH_00815 1.2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEAKJJMH_00816 3.1e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
MEAKJJMH_00817 1.4e-139 V MatE
MEAKJJMH_00818 1e-42 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEAKJJMH_00819 1.5e-86 S Alpha beta hydrolase
MEAKJJMH_00820 5.1e-93 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEAKJJMH_00821 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MEAKJJMH_00822 1.3e-111 argE 3.5.1.18 E Peptidase dimerisation domain
MEAKJJMH_00823 1.4e-101 IQ Enoyl-(Acyl carrier protein) reductase
MEAKJJMH_00824 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
MEAKJJMH_00825 1.3e-53 queT S QueT transporter
MEAKJJMH_00827 7.3e-65 degV S Uncharacterised protein, DegV family COG1307
MEAKJJMH_00828 2e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEAKJJMH_00829 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEAKJJMH_00830 1.9e-34 trxA O Belongs to the thioredoxin family
MEAKJJMH_00831 3.8e-87 S Sucrose-6F-phosphate phosphohydrolase
MEAKJJMH_00832 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MEAKJJMH_00833 1.3e-49 S Threonine/Serine exporter, ThrE
MEAKJJMH_00834 4.8e-81 thrE S Putative threonine/serine exporter
MEAKJJMH_00835 3.1e-27 cspC K Cold shock protein
MEAKJJMH_00836 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
MEAKJJMH_00837 8.1e-32 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MEAKJJMH_00838 1.8e-53 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MEAKJJMH_00839 3.1e-23
MEAKJJMH_00840 8.1e-58 3.6.1.27 I phosphatase
MEAKJJMH_00841 3.1e-25
MEAKJJMH_00842 2.1e-66 I alpha/beta hydrolase fold
MEAKJJMH_00843 1.3e-38 azlD S branched-chain amino acid
MEAKJJMH_00844 1.9e-104 azlC E AzlC protein
MEAKJJMH_00845 3.5e-17
MEAKJJMH_00846 4.9e-119 xth 3.1.11.2 L exodeoxyribonuclease III
MEAKJJMH_00847 9.2e-91 V domain protein
MEAKJJMH_00852 8.1e-09 S zinc-ribbon domain
MEAKJJMH_00854 4e-11 S Mor transcription activator family
MEAKJJMH_00855 2.3e-59 yfjR K WYL domain
MEAKJJMH_00856 6e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEAKJJMH_00857 6.4e-173 malY 4.4.1.8 E Aminotransferase, class I
MEAKJJMH_00858 4e-118 K AI-2E family transporter
MEAKJJMH_00859 1.2e-60 EG EamA-like transporter family
MEAKJJMH_00860 4.4e-75 L haloacid dehalogenase-like hydrolase
MEAKJJMH_00861 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MEAKJJMH_00862 2.9e-67 1.5.1.38 S NADPH-dependent FMN reductase
MEAKJJMH_00863 3.7e-164 C Luciferase-like monooxygenase
MEAKJJMH_00864 1.3e-41 K Transcriptional regulator, HxlR family
MEAKJJMH_00865 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MEAKJJMH_00866 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
MEAKJJMH_00867 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MEAKJJMH_00868 7e-82 pncA Q isochorismatase
MEAKJJMH_00869 4.6e-63 3.1.3.73 G phosphoglycerate mutase
MEAKJJMH_00870 9.5e-259 treB G phosphotransferase system
MEAKJJMH_00871 5.7e-84 treR K UTRA
MEAKJJMH_00872 2.2e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MEAKJJMH_00873 1.4e-167 mdtG EGP Major facilitator Superfamily
MEAKJJMH_00875 1.9e-197 XK27_08315 M Sulfatase
MEAKJJMH_00876 5.1e-56 S peptidoglycan catabolic process
MEAKJJMH_00877 1.1e-150 M BCCT, betaine/carnitine/choline family transporter
MEAKJJMH_00878 1.9e-84 M Nucleotidyl transferase
MEAKJJMH_00879 2.2e-177 licA 2.7.1.89 M Choline/ethanolamine kinase
MEAKJJMH_00880 6.2e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEAKJJMH_00881 4.4e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MEAKJJMH_00882 1.5e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEAKJJMH_00883 1.6e-176 thrC 4.2.3.1 E Threonine synthase
MEAKJJMH_00884 9.1e-132 S Bacterial membrane protein YfhO
MEAKJJMH_00885 3.6e-14
MEAKJJMH_00886 5.8e-76 S Psort location CytoplasmicMembrane, score
MEAKJJMH_00887 1.6e-145 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MEAKJJMH_00888 7.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
MEAKJJMH_00889 7e-157 XK27_09615 S reductase
MEAKJJMH_00890 1.1e-67 XK27_09620 S NADPH-dependent FMN reductase
MEAKJJMH_00891 5.6e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEAKJJMH_00892 7.3e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEAKJJMH_00893 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MEAKJJMH_00895 1.8e-153 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
MEAKJJMH_00896 1.6e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
MEAKJJMH_00897 7e-38 S Acyltransferase family
MEAKJJMH_00898 3.8e-43 S Peptidase_C39 like family
MEAKJJMH_00902 8.5e-64 M Glycosyltransferase like family 2
MEAKJJMH_00903 2.4e-73 M LicD family
MEAKJJMH_00904 1.5e-57 cps3F
MEAKJJMH_00905 7.5e-93 M transferase activity, transferring glycosyl groups
MEAKJJMH_00906 1.3e-76 waaB GT4 M Glycosyl transferases group 1
MEAKJJMH_00907 6.9e-92 M Core-2/I-Branching enzyme
MEAKJJMH_00908 6.2e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEAKJJMH_00909 6.2e-64 rny D Peptidase family M23
MEAKJJMH_00911 4e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MEAKJJMH_00912 1.6e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEAKJJMH_00913 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MEAKJJMH_00914 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MEAKJJMH_00915 2e-91 rfbP M Bacterial sugar transferase
MEAKJJMH_00916 2.5e-58 cpsF M Oligosaccharide biosynthesis protein Alg14 like
MEAKJJMH_00917 1.6e-75 xerC L Belongs to the 'phage' integrase family
MEAKJJMH_00918 3.8e-22
MEAKJJMH_00919 4.4e-09 K SIR2-like domain
MEAKJJMH_00920 2.4e-71 K SIR2-like domain
MEAKJJMH_00921 8e-112 K IrrE N-terminal-like domain
MEAKJJMH_00922 4.1e-18
MEAKJJMH_00923 7.2e-38 L hmm pf00665
MEAKJJMH_00924 1.8e-49 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
MEAKJJMH_00925 8.7e-51 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
MEAKJJMH_00926 3.4e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MEAKJJMH_00927 3.9e-133 coaA 2.7.1.33 F Pantothenic acid kinase
MEAKJJMH_00928 1.7e-44 E GDSL-like Lipase/Acylhydrolase
MEAKJJMH_00929 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEAKJJMH_00930 1.6e-189 glnPH2 P ABC transporter permease
MEAKJJMH_00931 2.1e-213 yjeM E Amino Acid
MEAKJJMH_00932 3.9e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
MEAKJJMH_00933 2.5e-137 tetA EGP Major facilitator Superfamily
MEAKJJMH_00934 1.3e-62 S Glycosyltransferase like family 2
MEAKJJMH_00935 1.5e-117 cps1D M Domain of unknown function (DUF4422)
MEAKJJMH_00936 4.3e-38 S CAAX protease self-immunity
MEAKJJMH_00937 2.8e-09 yvyE 3.4.13.9 S YigZ family
MEAKJJMH_00938 2.9e-65 yvyE 3.4.13.9 S YigZ family
MEAKJJMH_00939 2.3e-58 S Haloacid dehalogenase-like hydrolase
MEAKJJMH_00940 4.5e-154 EGP Major facilitator Superfamily
MEAKJJMH_00942 1.5e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MEAKJJMH_00943 2.1e-27 yraB K transcriptional regulator
MEAKJJMH_00944 3.7e-89 S NADPH-dependent FMN reductase
MEAKJJMH_00945 8.8e-102 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MEAKJJMH_00946 1.5e-55 S ECF transporter, substrate-specific component
MEAKJJMH_00947 2.1e-103 znuB U ABC 3 transport family
MEAKJJMH_00948 2.9e-98 fhuC P ABC transporter
MEAKJJMH_00949 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
MEAKJJMH_00950 9e-39
MEAKJJMH_00951 7.3e-14 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MEAKJJMH_00952 4.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
MEAKJJMH_00953 9.1e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEAKJJMH_00954 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
MEAKJJMH_00955 9.1e-108 spo0J K Belongs to the ParB family
MEAKJJMH_00956 6.5e-118 soj D Sporulation initiation inhibitor
MEAKJJMH_00957 9.5e-68 noc K Belongs to the ParB family
MEAKJJMH_00958 8.1e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MEAKJJMH_00959 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MEAKJJMH_00960 2.4e-109 3.1.4.46 C phosphodiesterase
MEAKJJMH_00961 0.0 pacL 3.6.3.8 P P-type ATPase
MEAKJJMH_00962 1.8e-61 yvdD 3.2.2.10 S Possible lysine decarboxylase
MEAKJJMH_00963 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MEAKJJMH_00965 5.2e-63 srtA 3.4.22.70 M sortase family
MEAKJJMH_00966 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MEAKJJMH_00967 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MEAKJJMH_00968 3.7e-34
MEAKJJMH_00969 4.5e-140 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEAKJJMH_00970 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEAKJJMH_00971 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEAKJJMH_00972 1.1e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
MEAKJJMH_00973 1.1e-39 ybjQ S Belongs to the UPF0145 family
MEAKJJMH_00974 5.7e-08
MEAKJJMH_00975 1.8e-95 V ABC transporter, ATP-binding protein
MEAKJJMH_00976 1.1e-41 gntR1 K Transcriptional regulator, GntR family
MEAKJJMH_00977 7.1e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MEAKJJMH_00978 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEAKJJMH_00979 1.1e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MEAKJJMH_00980 2.2e-107 terC P Integral membrane protein TerC family
MEAKJJMH_00981 1.2e-38 K Transcriptional regulator
MEAKJJMH_00982 7.5e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MEAKJJMH_00983 2e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEAKJJMH_00984 2.9e-101 tcyB E ABC transporter
MEAKJJMH_00985 2.3e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEAKJJMH_00986 4e-210 mtlR K Mga helix-turn-helix domain
MEAKJJMH_00987 2.6e-58 yjcE P Sodium proton antiporter
MEAKJJMH_00988 4.9e-105 yjcE P Sodium proton antiporter
MEAKJJMH_00989 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MEAKJJMH_00990 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
MEAKJJMH_00991 1e-67 dhaL 2.7.1.121 S Dak2
MEAKJJMH_00992 7.6e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MEAKJJMH_00993 1.2e-113 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MEAKJJMH_00994 1.7e-61 K Bacterial regulatory proteins, tetR family
MEAKJJMH_00995 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
MEAKJJMH_00997 7e-110 endA F DNA RNA non-specific endonuclease
MEAKJJMH_00998 9.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
MEAKJJMH_00999 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
MEAKJJMH_01000 6.8e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
MEAKJJMH_01001 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MEAKJJMH_01002 1e-57 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MEAKJJMH_01003 5.1e-77 azlC E branched-chain amino acid
MEAKJJMH_01004 2.6e-31 azlD S Branched-chain amino acid transport protein (AzlD)
MEAKJJMH_01005 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
MEAKJJMH_01006 1.6e-55 jag S R3H domain protein
MEAKJJMH_01007 4.5e-53 K Transcriptional regulator C-terminal region
MEAKJJMH_01008 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
MEAKJJMH_01009 1.5e-285 pepO 3.4.24.71 O Peptidase family M13
MEAKJJMH_01010 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
MEAKJJMH_01011 2.1e-07 yvaZ S SdpI/YhfL protein family
MEAKJJMH_01012 8.6e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MEAKJJMH_01013 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
MEAKJJMH_01014 1.3e-40 wecD K Acetyltransferase GNAT Family
MEAKJJMH_01016 1.3e-37 aguA_2 3.5.3.12 E Porphyromonas-type peptidyl-arginine deiminase
MEAKJJMH_01017 2.3e-252 XK27_06780 V ABC transporter permease
MEAKJJMH_01018 7.1e-95 XK27_06785 V ABC transporter, ATP-binding protein
MEAKJJMH_01019 3.2e-34 tetR K transcriptional regulator
MEAKJJMH_01020 3.1e-80 L Integrase
MEAKJJMH_01021 3.2e-27
MEAKJJMH_01022 2.2e-39
MEAKJJMH_01023 9.1e-167 2.7.1.176 S Zeta toxin
MEAKJJMH_01024 4.2e-43 S Bacterial epsilon antitoxin
MEAKJJMH_01025 2.3e-50
MEAKJJMH_01026 8.9e-143 repA S Replication initiator protein A
MEAKJJMH_01028 1.4e-125 D Sporulation initiation inhibitor
MEAKJJMH_01029 1.3e-80 L COG1961 Site-specific recombinases, DNA invertase Pin homologs
MEAKJJMH_01031 2.1e-12 K Bacterial regulatory proteins, tetR family
MEAKJJMH_01032 4e-76 S Protein of unknown function with HXXEE motif
MEAKJJMH_01033 3.9e-40 S Asp23 family, cell envelope-related function
MEAKJJMH_01034 1.3e-11 S Transglycosylase associated protein
MEAKJJMH_01035 1.5e-15
MEAKJJMH_01038 3.2e-141 L Transposase and inactivated derivatives, IS30 family
MEAKJJMH_01039 1.6e-131 G Polysaccharide deacetylase
MEAKJJMH_01040 3.3e-45 G Polysaccharide deacetylase
MEAKJJMH_01041 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MEAKJJMH_01042 1.6e-10 T Antidote-toxin recognition MazE, bacterial antitoxin
MEAKJJMH_01043 3e-147 mepA V MATE efflux family protein
MEAKJJMH_01044 1.1e-150 lsa S ABC transporter
MEAKJJMH_01045 2.8e-81 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEAKJJMH_01046 1e-109 puuD S peptidase C26
MEAKJJMH_01047 2.2e-201 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MEAKJJMH_01048 1.1e-25
MEAKJJMH_01049 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
MEAKJJMH_01050 1.7e-60 uspA T Universal stress protein family
MEAKJJMH_01052 3.6e-210 glnP P ABC transporter
MEAKJJMH_01053 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MEAKJJMH_01054 1.5e-30 tnp L MULE transposase domain
MEAKJJMH_01055 3.2e-103 pncA Q Isochorismatase family
MEAKJJMH_01056 1.8e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEAKJJMH_01057 1.1e-130 3.6.1.13, 3.6.1.55 F NUDIX domain
MEAKJJMH_01058 8.5e-64 V HNH endonuclease
MEAKJJMH_01060 1.2e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MEAKJJMH_01061 2.6e-55 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
MEAKJJMH_01062 4.9e-148 D CobQ CobB MinD ParA nucleotide binding domain protein
MEAKJJMH_01063 8.5e-35
MEAKJJMH_01064 6.2e-186 repA S Replication initiator protein A
MEAKJJMH_01065 4.9e-25
MEAKJJMH_01066 1.1e-138 S Fic/DOC family
MEAKJJMH_01067 4.3e-43 relB L Addiction module antitoxin, RelB DinJ family
MEAKJJMH_01068 8.3e-27
MEAKJJMH_01069 4.1e-29 S protein conserved in bacteria
MEAKJJMH_01070 4.9e-72 S protein conserved in bacteria
MEAKJJMH_01071 4e-41
MEAKJJMH_01072 2.8e-23
MEAKJJMH_01073 0.0 L MobA MobL family protein
MEAKJJMH_01074 2.4e-76 cylA V abc transporter atp-binding protein
MEAKJJMH_01075 4.1e-60 cylB V ABC-2 type transporter
MEAKJJMH_01076 7e-27 K LytTr DNA-binding domain
MEAKJJMH_01077 1.4e-10 S Protein of unknown function (DUF3021)
MEAKJJMH_01078 2.5e-158 L Transposase
MEAKJJMH_01079 1.1e-47 L Transposase
MEAKJJMH_01080 4.6e-79
MEAKJJMH_01081 1.1e-258 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MEAKJJMH_01082 8.5e-89 2.7.7.65 T phosphorelay sensor kinase activity
MEAKJJMH_01083 1.3e-132 cbiQ P Cobalt transport protein
MEAKJJMH_01084 1.3e-156 P ABC transporter
MEAKJJMH_01085 9.3e-147 cbiO2 P ABC transporter
MEAKJJMH_01086 4.4e-262 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MEAKJJMH_01087 4.9e-179 proV E ABC transporter, ATP-binding protein
MEAKJJMH_01088 2.6e-247 gshR 1.8.1.7 C Glutathione reductase
MEAKJJMH_01089 6.7e-105
MEAKJJMH_01090 2.5e-38 S RelB antitoxin
MEAKJJMH_01091 2.9e-289 norB EGP Major Facilitator
MEAKJJMH_01092 3e-99 K Bacterial regulatory proteins, tetR family
MEAKJJMH_01094 3.6e-234 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
MEAKJJMH_01095 7.1e-26 S Psort location Cytoplasmic, score
MEAKJJMH_01096 4.5e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
MEAKJJMH_01097 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
MEAKJJMH_01098 8e-73 prdD S An automated process has identified a potential problem with this gene model
MEAKJJMH_01099 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
MEAKJJMH_01100 7.8e-143 5.1.1.4 E Proline racemase
MEAKJJMH_01101 2.2e-93 XK27_00825 S Sulfite exporter TauE/SafE
MEAKJJMH_01102 4.1e-223 ybeC E amino acid
MEAKJJMH_01103 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
MEAKJJMH_01104 2.9e-07 S Protein of unknown function (DUF3343)
MEAKJJMH_01105 1.4e-137 selB J Elongation factor SelB, winged helix
MEAKJJMH_01106 8.8e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
MEAKJJMH_01107 9.1e-110 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
MEAKJJMH_01108 6.9e-29 yitW S Iron-sulfur cluster assembly protein
MEAKJJMH_01109 4.4e-175 rnfC C RnfC Barrel sandwich hybrid domain
MEAKJJMH_01110 7.8e-100 selD 2.7.9.3 E AIR synthase related protein, C-terminal domain
MEAKJJMH_01111 9.2e-148 yedE S Sulphur transport
MEAKJJMH_01112 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
MEAKJJMH_01113 2.9e-16 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
MEAKJJMH_01114 2.3e-57 yvbG U MarC family integral membrane protein
MEAKJJMH_01115 6.1e-181 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MEAKJJMH_01116 1.9e-49 S Membrane
MEAKJJMH_01117 2.2e-76 rhaR K helix_turn_helix, arabinose operon control protein
MEAKJJMH_01118 1.5e-188 iolF EGP Major facilitator Superfamily
MEAKJJMH_01119 2.9e-215 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MEAKJJMH_01120 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MEAKJJMH_01121 2.4e-218 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
MEAKJJMH_01122 1.5e-109 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MEAKJJMH_01124 1.7e-19 S YjcQ protein
MEAKJJMH_01125 7.6e-105 L Belongs to the 'phage' integrase family
MEAKJJMH_01126 5.7e-23 3.1.21.3 V Type I restriction modification DNA specificity domain
MEAKJJMH_01127 1.9e-59 hsdM 2.1.1.72 V type I restriction-modification system
MEAKJJMH_01128 4.3e-26 K Cro/C1-type HTH DNA-binding domain
MEAKJJMH_01129 2.6e-80 S Putative inner membrane protein (DUF1819)
MEAKJJMH_01130 6.9e-69 S Domain of unknown function (DUF1788)
MEAKJJMH_01131 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
MEAKJJMH_01132 0.0 V restriction
MEAKJJMH_01133 3.3e-310 S TIGR02687 family
MEAKJJMH_01134 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
MEAKJJMH_01135 1.1e-49
MEAKJJMH_01136 7.6e-38
MEAKJJMH_01137 1e-09
MEAKJJMH_01138 2.1e-16
MEAKJJMH_01139 5.5e-27
MEAKJJMH_01142 6.2e-167 potE2 E amino acid
MEAKJJMH_01143 4.3e-147 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MEAKJJMH_01144 1e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MEAKJJMH_01145 1.5e-57 racA K Domain of unknown function (DUF1836)
MEAKJJMH_01146 3.8e-79 yitS S EDD domain protein, DegV family
MEAKJJMH_01147 1.1e-45 yjaB_1 K Acetyltransferase (GNAT) domain
MEAKJJMH_01148 8.7e-07
MEAKJJMH_01149 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEAKJJMH_01150 0.0 O Belongs to the peptidase S8 family
MEAKJJMH_01151 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
MEAKJJMH_01152 2.8e-57 tlpA2 L Transposase IS200 like
MEAKJJMH_01154 3.4e-142 L transposase, IS605 OrfB family
MEAKJJMH_01155 4.6e-84 dps P Ferritin-like domain
MEAKJJMH_01156 4.3e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MEAKJJMH_01157 9.6e-44 L hmm pf00665
MEAKJJMH_01158 5e-18 tnp
MEAKJJMH_01159 8.7e-31 tnp L Transposase IS66 family
MEAKJJMH_01160 1.7e-32 P Heavy-metal-associated domain
MEAKJJMH_01161 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MEAKJJMH_01162 1.3e-20 L PFAM transposase IS3 IS911 family protein
MEAKJJMH_01163 1.4e-41 L Integrase core domain
MEAKJJMH_01164 2.4e-35 L Integrase core domain
MEAKJJMH_01165 2.6e-129 EGP Major Facilitator Superfamily
MEAKJJMH_01166 1.2e-97 EGP Major Facilitator Superfamily
MEAKJJMH_01167 1.3e-72 K Transcriptional regulator, LysR family
MEAKJJMH_01168 1.6e-138 G Xylose isomerase-like TIM barrel
MEAKJJMH_01169 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
MEAKJJMH_01170 1.6e-217 1.3.5.4 C FAD binding domain
MEAKJJMH_01171 1.3e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MEAKJJMH_01172 3.8e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MEAKJJMH_01173 1.1e-142 xerS L Phage integrase family
MEAKJJMH_01177 2e-91 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MEAKJJMH_01178 8.2e-13 ptp3 3.1.3.48 T Tyrosine phosphatase family
MEAKJJMH_01179 8.7e-39 ptp3 3.1.3.48 T Tyrosine phosphatase family
MEAKJJMH_01180 2.4e-75 desR K helix_turn_helix, Lux Regulon
MEAKJJMH_01181 3.2e-57 salK 2.7.13.3 T Histidine kinase
MEAKJJMH_01182 1.9e-53 yvfS V ABC-2 type transporter
MEAKJJMH_01183 5.2e-79 yvfR V ABC transporter
MEAKJJMH_01184 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEAKJJMH_01185 1.7e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MEAKJJMH_01186 1.2e-30
MEAKJJMH_01187 8.2e-16
MEAKJJMH_01188 4.7e-112 rssA S Phospholipase, patatin family
MEAKJJMH_01189 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEAKJJMH_01190 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MEAKJJMH_01191 9.6e-45 S VIT family
MEAKJJMH_01192 8.7e-60 L Transposase
MEAKJJMH_01193 4.2e-240 sufB O assembly protein SufB
MEAKJJMH_01194 1.4e-40 nifU C SUF system FeS assembly protein, NifU family
MEAKJJMH_01195 1.1e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEAKJJMH_01196 5.6e-143 sufD O FeS assembly protein SufD
MEAKJJMH_01197 8.1e-116 sufC O FeS assembly ATPase SufC
MEAKJJMH_01198 6e-222 E ABC transporter, substratebinding protein
MEAKJJMH_01199 8.5e-138 yfeO P Voltage gated chloride channel
MEAKJJMH_01200 1.4e-27 K Helix-turn-helix XRE-family like proteins
MEAKJJMH_01201 5.6e-136 pfoS S Phosphotransferase system, EIIC
MEAKJJMH_01202 7.2e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MEAKJJMH_01203 8.8e-66 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
MEAKJJMH_01204 1.2e-35 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MEAKJJMH_01205 3.9e-134 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
MEAKJJMH_01206 2.2e-83 srlA G PTS system enzyme II sorbitol-specific factor
MEAKJJMH_01207 9.9e-43 gutM K Glucitol operon activator protein (GutM)
MEAKJJMH_01208 2.9e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
MEAKJJMH_01209 3.6e-111 IQ NAD dependent epimerase/dehydratase family
MEAKJJMH_01210 1e-26 yuaG 3.4.21.72 M by MetaGeneAnnotator
MEAKJJMH_01211 1.7e-39 M Phage tail tape measure protein TP901
MEAKJJMH_01215 4.8e-29 S Phage Mu protein F like protein
MEAKJJMH_01216 2.7e-99 fabK 1.3.1.9 S Nitronate monooxygenase
MEAKJJMH_01217 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MEAKJJMH_01219 1.8e-265 fbp 3.1.3.11 G phosphatase activity
MEAKJJMH_01220 2.2e-71 xerD L Phage integrase, N-terminal SAM-like domain
MEAKJJMH_01224 3.2e-84 mesE M Transport protein ComB
MEAKJJMH_01225 8.4e-280 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MEAKJJMH_01227 6.2e-55 K LytTr DNA-binding domain
MEAKJJMH_01228 1.4e-51 2.7.13.3 T GHKL domain
MEAKJJMH_01233 1.1e-16
MEAKJJMH_01235 4.2e-08
MEAKJJMH_01236 2e-39 blpT
MEAKJJMH_01237 2.3e-14
MEAKJJMH_01239 2.3e-186 mtnE 2.6.1.83 E Aminotransferase
MEAKJJMH_01240 4.5e-82 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MEAKJJMH_01241 1.3e-66 S Protein of unknown function (DUF1440)
MEAKJJMH_01242 7.7e-41 S Iron-sulfur cluster assembly protein
MEAKJJMH_01243 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MEAKJJMH_01244 1.1e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MEAKJJMH_01245 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEAKJJMH_01246 7.4e-153 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEAKJJMH_01247 4e-64 G Xylose isomerase domain protein TIM barrel
MEAKJJMH_01248 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
MEAKJJMH_01249 6.5e-90 nanK GK ROK family
MEAKJJMH_01250 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MEAKJJMH_01251 3.6e-91 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MEAKJJMH_01252 9.6e-75 K Helix-turn-helix domain, rpiR family
MEAKJJMH_01253 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
MEAKJJMH_01254 4.5e-216 yjeM E Amino Acid
MEAKJJMH_01256 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEAKJJMH_01257 6.9e-233 tetP J elongation factor G
MEAKJJMH_01258 5.2e-276 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEAKJJMH_01259 2.3e-87 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MEAKJJMH_01260 1.1e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
MEAKJJMH_01261 1.2e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
MEAKJJMH_01262 2.4e-181 gatC G PTS system sugar-specific permease component
MEAKJJMH_01263 2e-35 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MEAKJJMH_01264 2.1e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEAKJJMH_01265 2.2e-60 K DeoR C terminal sensor domain
MEAKJJMH_01266 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MEAKJJMH_01267 3.2e-78 S Fic/DOC family
MEAKJJMH_01268 5.2e-134 L PLD-like domain
MEAKJJMH_01269 3e-39 L PLD-like domain
MEAKJJMH_01271 2.3e-07 G SMI1 / KNR4 family (SUKH-1)
MEAKJJMH_01272 9.4e-109 L Initiator Replication protein
MEAKJJMH_01273 5.1e-38 S Replication initiator protein A (RepA) N-terminus
MEAKJJMH_01274 5.7e-128 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEAKJJMH_01275 1.6e-37 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEAKJJMH_01276 8.4e-91 2.7.1.193, 2.7.1.199, 2.7.1.208, 2.7.1.211 G .Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome down-regulated in Spo0A mutant
MEAKJJMH_01277 6e-17 bglG K antiterminator
MEAKJJMH_01278 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
MEAKJJMH_01280 1.4e-35
MEAKJJMH_01281 0.0 pepN 3.4.11.2 E aminopeptidase
MEAKJJMH_01282 6e-44 2.7.13.3 T protein histidine kinase activity
MEAKJJMH_01283 1.5e-34 agrA KT Response regulator of the LytR AlgR family
MEAKJJMH_01284 4.4e-21 M domain protein
MEAKJJMH_01285 2.2e-108 XK27_09655 S Virulence protein RhuM family
MEAKJJMH_01286 3.6e-125 yvgN C Aldo keto reductase
MEAKJJMH_01287 2e-104 yraQ S Predicted permease
MEAKJJMH_01288 3.1e-62 yeeE S Sulphur transport
MEAKJJMH_01289 5.4e-17 yeeD O Belongs to the sulfur carrier protein TusA family
MEAKJJMH_01290 1.9e-115 ynjE 2.8.1.11 P Rhodanese Homology Domain
MEAKJJMH_01292 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
MEAKJJMH_01293 4.3e-113 L Transposase IS66 family
MEAKJJMH_01294 3.9e-147 scrR K helix_turn _helix lactose operon repressor
MEAKJJMH_01295 1.4e-217 scrB 3.2.1.26 GH32 G invertase
MEAKJJMH_01296 3.1e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
MEAKJJMH_01297 1.2e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MEAKJJMH_01298 7.1e-115 ntpJ P Potassium uptake protein
MEAKJJMH_01299 2.2e-58 ktrA P TrkA-N domain
MEAKJJMH_01300 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MEAKJJMH_01301 2.4e-43 K helix_turn_helix isocitrate lyase regulation
MEAKJJMH_01302 1.5e-119 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAKJJMH_01303 7.6e-101 pfoS S Phosphotransferase system, EIIC
MEAKJJMH_01304 7.2e-19
MEAKJJMH_01305 1e-60 K helix_turn_helix, arabinose operon control protein
MEAKJJMH_01306 5.7e-140 G PFAM major facilitator superfamily MFS_1
MEAKJJMH_01307 7.6e-104 S Phospholipase/Carboxylesterase
MEAKJJMH_01308 1.4e-79 bglK_1 GK ROK family
MEAKJJMH_01309 2.4e-246 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEAKJJMH_01310 2.6e-53 S Predicted membrane protein (DUF2207)
MEAKJJMH_01311 1.2e-42 S Predicted membrane protein (DUF2207)
MEAKJJMH_01312 1.6e-54 bioY S BioY family
MEAKJJMH_01313 4.5e-181 lmrB EGP Major facilitator Superfamily
MEAKJJMH_01314 6.3e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEAKJJMH_01315 1.3e-73 glcR K DeoR C terminal sensor domain
MEAKJJMH_01316 5.9e-61 yceE S haloacid dehalogenase-like hydrolase
MEAKJJMH_01317 4.3e-41 S CAAX protease self-immunity
MEAKJJMH_01318 3.1e-34 S Domain of unknown function (DUF4811)
MEAKJJMH_01319 2.1e-197 lmrB EGP Major facilitator Superfamily
MEAKJJMH_01320 4.2e-32 merR K MerR HTH family regulatory protein
MEAKJJMH_01321 6.7e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEAKJJMH_01322 1.2e-70 S Protein of unknown function (DUF554)
MEAKJJMH_01323 1.8e-120 G Bacterial extracellular solute-binding protein
MEAKJJMH_01324 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
MEAKJJMH_01325 1.6e-100 baeS T Histidine kinase
MEAKJJMH_01326 3.7e-81 rbsB G sugar-binding domain protein
MEAKJJMH_01327 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MEAKJJMH_01328 6.4e-116 manY G PTS system sorbose-specific iic component
MEAKJJMH_01329 6.1e-147 manN G system, mannose fructose sorbose family IID component
MEAKJJMH_01330 3.2e-52 manO S Domain of unknown function (DUF956)
MEAKJJMH_01331 6e-70 mltD CBM50 M NlpC P60 family protein
MEAKJJMH_01332 8.1e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEAKJJMH_01333 4.2e-164 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAKJJMH_01334 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
MEAKJJMH_01335 1e-47 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MEAKJJMH_01336 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MEAKJJMH_01337 1.3e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEAKJJMH_01338 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEAKJJMH_01339 1.4e-47 S CRISPR-associated protein (Cas_Csn2)
MEAKJJMH_01340 7.8e-38 K transcriptional regulator PadR family
MEAKJJMH_01341 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
MEAKJJMH_01342 1.2e-15 S Putative adhesin
MEAKJJMH_01343 2.2e-16 pspC KT PspC domain
MEAKJJMH_01344 1.8e-13 S Enterocin A Immunity
MEAKJJMH_01345 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEAKJJMH_01346 5.7e-261 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
MEAKJJMH_01347 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MEAKJJMH_01348 2.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MEAKJJMH_01349 1.5e-120 potB P ABC transporter permease
MEAKJJMH_01350 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
MEAKJJMH_01351 1.3e-159 potD P ABC transporter
MEAKJJMH_01352 3.5e-132 ABC-SBP S ABC transporter
MEAKJJMH_01353 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MEAKJJMH_01354 1e-107 XK27_08845 S ABC transporter, ATP-binding protein
MEAKJJMH_01355 3.7e-66 M ErfK YbiS YcfS YnhG
MEAKJJMH_01356 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEAKJJMH_01357 6.5e-225 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEAKJJMH_01358 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEAKJJMH_01359 1.2e-102 pgm3 G phosphoglycerate mutase
MEAKJJMH_01360 1.5e-57 S CAAX protease self-immunity
MEAKJJMH_01361 1.1e-46 C Flavodoxin
MEAKJJMH_01362 1.5e-57 yphH S Cupin domain
MEAKJJMH_01364 2.9e-29 yphJ 4.1.1.44 S decarboxylase
MEAKJJMH_01365 7.8e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
MEAKJJMH_01366 7.4e-107 metQ1 P Belongs to the nlpA lipoprotein family
MEAKJJMH_01367 4.4e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEAKJJMH_01368 1.3e-69 metI P ABC transporter permease
MEAKJJMH_01369 6.7e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MEAKJJMH_01370 3e-84 drgA C nitroreductase
MEAKJJMH_01371 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
MEAKJJMH_01372 5.9e-107 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
MEAKJJMH_01373 1.2e-170 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MEAKJJMH_01374 5.7e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MEAKJJMH_01376 3.1e-150 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEAKJJMH_01377 2.4e-31 metI U ABC transporter permease
MEAKJJMH_01378 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
MEAKJJMH_01379 8.2e-54 S Protein of unknown function (DUF4256)
MEAKJJMH_01381 0.0 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
MEAKJJMH_01382 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MEAKJJMH_01383 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MEAKJJMH_01384 4.5e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEAKJJMH_01385 4e-230 lpdA 1.8.1.4 C Dehydrogenase
MEAKJJMH_01386 4e-112 lplA 6.3.1.20 H Lipoate-protein ligase
MEAKJJMH_01387 9.3e-56 S Protein of unknown function (DUF975)
MEAKJJMH_01388 1.3e-77 E GDSL-like Lipase/Acylhydrolase family
MEAKJJMH_01389 1.8e-38
MEAKJJMH_01390 4.1e-27 gcvR T Belongs to the UPF0237 family
MEAKJJMH_01391 4.6e-220 XK27_08635 S UPF0210 protein
MEAKJJMH_01392 4.5e-87 fruR K DeoR C terminal sensor domain
MEAKJJMH_01393 2e-150 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MEAKJJMH_01394 3e-284 fruA 2.7.1.202 GT Phosphotransferase System
MEAKJJMH_01395 2e-49 cps3F
MEAKJJMH_01396 2.7e-83 S Membrane
MEAKJJMH_01397 1.8e-254 E Amino acid permease
MEAKJJMH_01398 4.2e-162 cadA P P-type ATPase
MEAKJJMH_01399 1.8e-53 cadA P P-type ATPase
MEAKJJMH_01400 6.4e-114 degV S EDD domain protein, DegV family
MEAKJJMH_01401 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MEAKJJMH_01402 7.3e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
MEAKJJMH_01403 7.2e-27 ydiI Q Thioesterase superfamily
MEAKJJMH_01404 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MEAKJJMH_01405 9.6e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MEAKJJMH_01406 6.1e-81 S L,D-transpeptidase catalytic domain
MEAKJJMH_01407 4.4e-165 EGP Major facilitator Superfamily
MEAKJJMH_01408 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
MEAKJJMH_01409 1.2e-226 pipD E Dipeptidase
MEAKJJMH_01410 4.1e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MEAKJJMH_01411 2.6e-32 ywjH S Protein of unknown function (DUF1634)
MEAKJJMH_01412 1.7e-119 yxaA S membrane transporter protein
MEAKJJMH_01413 7.6e-83 lysR5 K LysR substrate binding domain
MEAKJJMH_01414 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
MEAKJJMH_01415 1.2e-13 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MEAKJJMH_01416 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MEAKJJMH_01417 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MEAKJJMH_01418 5.5e-243 lysP E amino acid
MEAKJJMH_01419 2.1e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEAKJJMH_01420 1.2e-97 L AAA ATPase domain
MEAKJJMH_01421 7.3e-46 L Transposase
MEAKJJMH_01424 2.6e-95 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MEAKJJMH_01439 2.1e-07
MEAKJJMH_01441 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEAKJJMH_01442 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEAKJJMH_01443 2.4e-192 cycA E Amino acid permease
MEAKJJMH_01444 8.3e-187 ytgP S Polysaccharide biosynthesis protein
MEAKJJMH_01445 3.3e-63 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEAKJJMH_01446 4.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEAKJJMH_01447 3.3e-192 pepV 3.5.1.18 E dipeptidase PepV
MEAKJJMH_01448 1.2e-111 2.1.1.72, 3.1.21.4 L restriction endonuclease
MEAKJJMH_01449 7.7e-261 L Type III restriction enzyme, res subunit
MEAKJJMH_01451 4.2e-115 L Type III restriction enzyme, res subunit
MEAKJJMH_01453 1.3e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MEAKJJMH_01454 5e-187 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEAKJJMH_01455 6.3e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MEAKJJMH_01456 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MEAKJJMH_01457 3.8e-120 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEAKJJMH_01459 3.7e-55 ctsR K Belongs to the CtsR family
MEAKJJMH_01460 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEAKJJMH_01461 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEAKJJMH_01462 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEAKJJMH_01463 4.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
MEAKJJMH_01464 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEAKJJMH_01465 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEAKJJMH_01466 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEAKJJMH_01467 1e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MEAKJJMH_01468 8.9e-90 patB 4.4.1.8 E Aminotransferase, class I
MEAKJJMH_01469 2.5e-113 K response regulator
MEAKJJMH_01470 1.7e-141 hpk31 2.7.13.3 T Histidine kinase
MEAKJJMH_01471 1.5e-91 lacX 5.1.3.3 G Aldose 1-epimerase
MEAKJJMH_01472 3.9e-146 G Transporter, major facilitator family protein
MEAKJJMH_01473 2.4e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEAKJJMH_01474 5.6e-246 yhcA V ABC transporter, ATP-binding protein
MEAKJJMH_01475 5.8e-35 K Bacterial regulatory proteins, tetR family
MEAKJJMH_01476 7.2e-148 lmrA V ABC transporter, ATP-binding protein
MEAKJJMH_01477 1.3e-66 lmrA V ABC transporter, ATP-binding protein
MEAKJJMH_01478 7.4e-253 yfiC V ABC transporter
MEAKJJMH_01480 2.7e-44 yjcF K protein acetylation
MEAKJJMH_01481 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
MEAKJJMH_01482 1.5e-71 lemA S LemA family
MEAKJJMH_01483 3e-114 htpX O Belongs to the peptidase M48B family
MEAKJJMH_01485 6.7e-233 helD 3.6.4.12 L DNA helicase
MEAKJJMH_01486 9.3e-128 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEAKJJMH_01487 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEAKJJMH_01488 2.7e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MEAKJJMH_01489 8.4e-83 ybhF_2 V abc transporter atp-binding protein
MEAKJJMH_01490 1.6e-104 ybhR V ABC transporter
MEAKJJMH_01491 3.9e-31 K Bacterial regulatory proteins, tetR family
MEAKJJMH_01492 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
MEAKJJMH_01493 1.3e-152 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MEAKJJMH_01494 7.8e-129
MEAKJJMH_01495 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEAKJJMH_01496 8.3e-105 tatD L hydrolase, TatD family
MEAKJJMH_01497 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MEAKJJMH_01498 1.7e-133 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEAKJJMH_01499 1.2e-22 veg S Biofilm formation stimulator VEG
MEAKJJMH_01500 2.8e-90 S Alpha/beta hydrolase of unknown function (DUF915)
MEAKJJMH_01501 3.6e-133 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
MEAKJJMH_01502 6.6e-46 argR K Regulates arginine biosynthesis genes
MEAKJJMH_01503 4.8e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEAKJJMH_01504 3.5e-156 amtB P ammonium transporter
MEAKJJMH_01506 2.5e-200 argH 4.3.2.1 E argininosuccinate lyase
MEAKJJMH_01507 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEAKJJMH_01508 1.5e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MEAKJJMH_01509 3.1e-128 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEAKJJMH_01510 4.4e-101 pfoS S Phosphotransferase system, EIIC
MEAKJJMH_01511 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEAKJJMH_01512 6.6e-53 adhR K helix_turn_helix, mercury resistance
MEAKJJMH_01513 5.2e-137 purR 2.4.2.7 F pur operon repressor
MEAKJJMH_01514 4.7e-46 EGP Transmembrane secretion effector
MEAKJJMH_01515 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEAKJJMH_01516 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEAKJJMH_01517 1.3e-18 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MEAKJJMH_01518 5.8e-112 dkg S reductase
MEAKJJMH_01519 1.7e-24
MEAKJJMH_01520 6e-79 2.4.2.3 F Phosphorylase superfamily
MEAKJJMH_01521 1.4e-290 ybiT S ABC transporter, ATP-binding protein
MEAKJJMH_01522 1.3e-61 bCE_4747 S Beta-lactamase superfamily domain
MEAKJJMH_01523 1.3e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEAKJJMH_01524 1.3e-124 S overlaps another CDS with the same product name
MEAKJJMH_01525 2.2e-86 S overlaps another CDS with the same product name
MEAKJJMH_01527 2.1e-54 spoVK O ATPase family associated with various cellular activities (AAA)
MEAKJJMH_01528 7.8e-23
MEAKJJMH_01529 3.2e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
MEAKJJMH_01531 1.8e-47
MEAKJJMH_01532 3.1e-21
MEAKJJMH_01533 1.4e-97 ydcZ S Putative inner membrane exporter, YdcZ
MEAKJJMH_01534 1.2e-88 S hydrolase
MEAKJJMH_01535 2.5e-205 ywfO S HD domain protein
MEAKJJMH_01536 9.8e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
MEAKJJMH_01537 1.8e-32 ywiB S Domain of unknown function (DUF1934)
MEAKJJMH_01538 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MEAKJJMH_01539 1.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEAKJJMH_01542 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEAKJJMH_01543 1.3e-187 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MEAKJJMH_01544 3.6e-41 rpmE2 J Ribosomal protein L31
MEAKJJMH_01545 1.3e-61
MEAKJJMH_01546 2.9e-257 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
MEAKJJMH_01548 6.8e-78 S Cell surface protein
MEAKJJMH_01551 1.6e-180 pbuG S permease
MEAKJJMH_01552 2.7e-83 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEAKJJMH_01554 2.9e-60 M ErfK YbiS YcfS YnhG
MEAKJJMH_01555 2.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
MEAKJJMH_01556 6.9e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEAKJJMH_01557 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MEAKJJMH_01558 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEAKJJMH_01559 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEAKJJMH_01560 5.4e-13
MEAKJJMH_01561 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
MEAKJJMH_01562 1.6e-90 yunF F Protein of unknown function DUF72
MEAKJJMH_01563 9.5e-155 nrnB S DHHA1 domain
MEAKJJMH_01564 4.8e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MEAKJJMH_01565 2.2e-59
MEAKJJMH_01566 8.6e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
MEAKJJMH_01567 2e-22 S Cytochrome B5
MEAKJJMH_01568 2.6e-18 yvrI K RNA polymerase sigma factor, sigma-70 family
MEAKJJMH_01569 6.9e-70 recX 2.4.1.337 GT4 S Regulatory protein RecX
MEAKJJMH_01570 1.6e-191 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEAKJJMH_01571 2.6e-97 ygaC J Belongs to the UPF0374 family
MEAKJJMH_01572 5.3e-92 yueF S AI-2E family transporter
MEAKJJMH_01573 2.5e-157 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MEAKJJMH_01574 1.8e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MEAKJJMH_01575 7.5e-278 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MEAKJJMH_01576 0.0 lacL 3.2.1.23 G -beta-galactosidase
MEAKJJMH_01577 2.6e-288 lacS G Transporter
MEAKJJMH_01578 1e-110 galR K Transcriptional regulator
MEAKJJMH_01579 1.2e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEAKJJMH_01580 1.5e-162 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MEAKJJMH_01581 2.4e-201 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MEAKJJMH_01582 0.0 rafA 3.2.1.22 G alpha-galactosidase
MEAKJJMH_01583 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
MEAKJJMH_01584 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
MEAKJJMH_01585 0.0 clpE O Belongs to the ClpA ClpB family
MEAKJJMH_01586 1.5e-15
MEAKJJMH_01587 9.7e-37 ptsH G phosphocarrier protein HPR
MEAKJJMH_01588 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEAKJJMH_01589 3.6e-163 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MEAKJJMH_01590 7.7e-127 cpoA GT4 M Glycosyltransferase, group 1 family protein
MEAKJJMH_01591 6.6e-126 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEAKJJMH_01592 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
MEAKJJMH_01593 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEAKJJMH_01595 2.7e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
MEAKJJMH_01596 1.2e-113 S N-acetylmuramoyl-L-alanine amidase activity
MEAKJJMH_01597 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MEAKJJMH_01598 1.1e-68 coiA 3.6.4.12 S Competence protein
MEAKJJMH_01599 1.5e-232 pepF E oligoendopeptidase F
MEAKJJMH_01600 1.3e-41 yjbH Q Thioredoxin
MEAKJJMH_01601 6.4e-98 pstS P Phosphate
MEAKJJMH_01602 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
MEAKJJMH_01603 5.1e-122 pstA P Phosphate transport system permease protein PstA
MEAKJJMH_01604 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEAKJJMH_01605 1.4e-83 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEAKJJMH_01606 1.1e-23 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEAKJJMH_01607 2.1e-56 P Plays a role in the regulation of phosphate uptake
MEAKJJMH_01608 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MEAKJJMH_01609 4.1e-79 S VIT family
MEAKJJMH_01610 9.4e-84 S membrane
MEAKJJMH_01611 1.6e-40 M1-874 K Domain of unknown function (DUF1836)
MEAKJJMH_01612 5.2e-65 hly S protein, hemolysin III
MEAKJJMH_01613 7.1e-35 K helix_turn_helix, Arsenical Resistance Operon Repressor
MEAKJJMH_01614 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEAKJJMH_01617 2.6e-13
MEAKJJMH_01618 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MEAKJJMH_01619 1.3e-158 ccpA K catabolite control protein A
MEAKJJMH_01620 3.7e-42 S VanZ like family
MEAKJJMH_01621 1.5e-119 yebC K Transcriptional regulatory protein
MEAKJJMH_01622 1e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEAKJJMH_01623 8.1e-121 comGA NU Type II IV secretion system protein
MEAKJJMH_01624 5.7e-98 comGB NU type II secretion system
MEAKJJMH_01625 1.2e-27 comGC U competence protein ComGC
MEAKJJMH_01626 1.5e-13
MEAKJJMH_01628 5.5e-11 S Putative Competence protein ComGF
MEAKJJMH_01630 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
MEAKJJMH_01631 1.6e-183 cycA E Amino acid permease
MEAKJJMH_01632 3e-57 S Calcineurin-like phosphoesterase
MEAKJJMH_01633 1.9e-53 yutD S Protein of unknown function (DUF1027)
MEAKJJMH_01634 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MEAKJJMH_01635 2.5e-30 S Protein of unknown function (DUF1461)
MEAKJJMH_01636 5.1e-92 dedA S SNARE associated Golgi protein
MEAKJJMH_01637 7.2e-96 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MEAKJJMH_01638 8.8e-50 yugI 5.3.1.9 J general stress protein
MEAKJJMH_01640 1.1e-35
MEAKJJMH_01641 9.8e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEAKJJMH_01642 4.2e-61 marR K Transcriptional regulator, MarR family
MEAKJJMH_01643 3.2e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEAKJJMH_01644 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEAKJJMH_01645 2.3e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MEAKJJMH_01646 1.1e-98 IQ reductase
MEAKJJMH_01647 1.8e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEAKJJMH_01648 3.9e-46 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEAKJJMH_01649 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEAKJJMH_01650 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MEAKJJMH_01651 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEAKJJMH_01652 2e-101 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MEAKJJMH_01653 1.2e-108 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MEAKJJMH_01654 4.3e-230 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEAKJJMH_01655 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
MEAKJJMH_01656 1.2e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEAKJJMH_01657 5.7e-119 gla U Major intrinsic protein
MEAKJJMH_01658 1.5e-45 ykuL S CBS domain
MEAKJJMH_01659 3.9e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MEAKJJMH_01660 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MEAKJJMH_01661 1.5e-86 ykuT M mechanosensitive ion channel
MEAKJJMH_01663 2.3e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MEAKJJMH_01664 2e-21 yheA S Belongs to the UPF0342 family
MEAKJJMH_01665 1.9e-127 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
MEAKJJMH_01666 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEAKJJMH_01668 5.4e-53 hit FG histidine triad
MEAKJJMH_01669 1.3e-94 ecsA V ABC transporter, ATP-binding protein
MEAKJJMH_01670 2.4e-71 ecsB U ABC transporter
MEAKJJMH_01671 1e-97 ytmP 2.7.1.89 M Choline/ethanolamine kinase
MEAKJJMH_01672 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEAKJJMH_01673 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MEAKJJMH_01674 3.4e-75 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEAKJJMH_01675 2.6e-239 sftA D Belongs to the FtsK SpoIIIE SftA family
MEAKJJMH_01676 2.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MEAKJJMH_01677 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
MEAKJJMH_01678 5.1e-69 ybhL S Belongs to the BI1 family
MEAKJJMH_01679 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEAKJJMH_01680 1.5e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MEAKJJMH_01681 7.8e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEAKJJMH_01682 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEAKJJMH_01683 2.8e-79 dnaB L replication initiation and membrane attachment
MEAKJJMH_01684 9.7e-108 dnaI L Primosomal protein DnaI
MEAKJJMH_01685 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEAKJJMH_01686 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEAKJJMH_01687 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MEAKJJMH_01688 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEAKJJMH_01689 2.5e-71 yqeG S HAD phosphatase, family IIIA
MEAKJJMH_01690 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
MEAKJJMH_01691 1e-29 yhbY J RNA-binding protein
MEAKJJMH_01692 2.1e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEAKJJMH_01693 1.6e-71 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MEAKJJMH_01694 5.1e-49 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEAKJJMH_01695 5.5e-82 H Nodulation protein S (NodS)
MEAKJJMH_01696 1.3e-122 ylbM S Belongs to the UPF0348 family
MEAKJJMH_01697 3.5e-57 yceD S Uncharacterized ACR, COG1399
MEAKJJMH_01698 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MEAKJJMH_01699 4e-89 plsC 2.3.1.51 I Acyltransferase
MEAKJJMH_01700 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
MEAKJJMH_01701 1.5e-27 yazA L GIY-YIG catalytic domain protein
MEAKJJMH_01702 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
MEAKJJMH_01703 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEAKJJMH_01704 6.9e-37
MEAKJJMH_01705 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MEAKJJMH_01706 9.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEAKJJMH_01707 3.8e-159 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEAKJJMH_01708 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MEAKJJMH_01709 2.3e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEAKJJMH_01711 3.1e-111 K response regulator
MEAKJJMH_01712 1.3e-167 arlS 2.7.13.3 T Histidine kinase
MEAKJJMH_01713 6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEAKJJMH_01714 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MEAKJJMH_01715 5.6e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MEAKJJMH_01716 2.1e-104
MEAKJJMH_01717 5.5e-117
MEAKJJMH_01718 4.2e-40 dut S dUTPase
MEAKJJMH_01719 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEAKJJMH_01720 3.7e-46 yqhY S Asp23 family, cell envelope-related function
MEAKJJMH_01721 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEAKJJMH_01722 1.7e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEAKJJMH_01723 2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEAKJJMH_01724 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEAKJJMH_01725 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MEAKJJMH_01726 3.4e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MEAKJJMH_01727 6.6e-49 argR K Regulates arginine biosynthesis genes
MEAKJJMH_01728 7.1e-178 recN L May be involved in recombinational repair of damaged DNA
MEAKJJMH_01729 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEAKJJMH_01730 2.2e-30 ynzC S UPF0291 protein
MEAKJJMH_01731 2.9e-26 yneF S UPF0154 protein
MEAKJJMH_01732 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
MEAKJJMH_01733 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MEAKJJMH_01734 1e-76 yciQ P membrane protein (DUF2207)
MEAKJJMH_01735 5.1e-19 D nuclear chromosome segregation
MEAKJJMH_01736 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MEAKJJMH_01737 7.4e-39 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MEAKJJMH_01738 2.2e-69 gluP 3.4.21.105 S Peptidase, S54 family
MEAKJJMH_01739 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
MEAKJJMH_01740 4.7e-158 glk 2.7.1.2 G Glucokinase
MEAKJJMH_01741 2.7e-46 yqhL P Rhodanese-like protein
MEAKJJMH_01742 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
MEAKJJMH_01743 2.7e-110 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEAKJJMH_01744 6.8e-205 ynbB 4.4.1.1 P aluminum resistance
MEAKJJMH_01745 1.3e-45 glnR K Transcriptional regulator
MEAKJJMH_01746 2e-247 glnA 6.3.1.2 E glutamine synthetase
MEAKJJMH_01748 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEAKJJMH_01749 2.7e-48 S Domain of unknown function (DUF956)
MEAKJJMH_01750 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MEAKJJMH_01751 1e-80 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEAKJJMH_01752 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEAKJJMH_01753 6.7e-102 cdsA 2.7.7.41 S Belongs to the CDS family
MEAKJJMH_01754 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MEAKJJMH_01755 4.5e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEAKJJMH_01756 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEAKJJMH_01757 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
MEAKJJMH_01758 4.8e-170 nusA K Participates in both transcription termination and antitermination
MEAKJJMH_01759 1.4e-39 ylxR K Protein of unknown function (DUF448)
MEAKJJMH_01760 6.9e-26 ylxQ J ribosomal protein
MEAKJJMH_01761 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEAKJJMH_01762 2.4e-54 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEAKJJMH_01763 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEAKJJMH_01764 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MEAKJJMH_01765 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEAKJJMH_01766 2.1e-55 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEAKJJMH_01767 1.5e-274 dnaK O Heat shock 70 kDa protein
MEAKJJMH_01768 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEAKJJMH_01769 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEAKJJMH_01771 2.1e-205 glnP P ABC transporter
MEAKJJMH_01772 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MEAKJJMH_01773 1.5e-31
MEAKJJMH_01774 2e-111 ampC V Beta-lactamase
MEAKJJMH_01775 2.7e-110 cobQ S glutamine amidotransferase
MEAKJJMH_01776 1.4e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MEAKJJMH_01777 6.8e-86 tdk 2.7.1.21 F thymidine kinase
MEAKJJMH_01778 1.5e-176 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEAKJJMH_01779 5.3e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEAKJJMH_01780 1e-134 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEAKJJMH_01781 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEAKJJMH_01782 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
MEAKJJMH_01783 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEAKJJMH_01784 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEAKJJMH_01785 7e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEAKJJMH_01786 1.8e-265 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEAKJJMH_01787 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEAKJJMH_01788 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEAKJJMH_01789 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MEAKJJMH_01790 4.1e-15 ywzB S Protein of unknown function (DUF1146)
MEAKJJMH_01791 5.4e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEAKJJMH_01792 3.4e-167 mbl D Cell shape determining protein MreB Mrl
MEAKJJMH_01793 9e-27 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MEAKJJMH_01794 1.3e-13 S Protein of unknown function (DUF2969)
MEAKJJMH_01795 6.1e-187 rodA D Belongs to the SEDS family
MEAKJJMH_01796 2.7e-26 arsC 1.20.4.1 P Belongs to the ArsC family
MEAKJJMH_01797 1.2e-93 2.7.1.89 M Phosphotransferase enzyme family
MEAKJJMH_01798 6.2e-103 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MEAKJJMH_01799 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEAKJJMH_01800 1.3e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEAKJJMH_01801 3.2e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEAKJJMH_01802 4.4e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEAKJJMH_01803 7.5e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MEAKJJMH_01804 1.9e-90 stp 3.1.3.16 T phosphatase
MEAKJJMH_01805 7.5e-191 KLT serine threonine protein kinase
MEAKJJMH_01806 1.1e-108 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEAKJJMH_01807 4.1e-60 thiN 2.7.6.2 H thiamine pyrophosphokinase
MEAKJJMH_01808 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MEAKJJMH_01809 4.5e-53 asp S Asp23 family, cell envelope-related function
MEAKJJMH_01810 3.3e-239 yloV S DAK2 domain fusion protein YloV
MEAKJJMH_01811 5.2e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEAKJJMH_01812 1.6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEAKJJMH_01813 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEAKJJMH_01814 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEAKJJMH_01815 2.3e-218 smc D Required for chromosome condensation and partitioning
MEAKJJMH_01816 2.3e-144 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEAKJJMH_01817 4.5e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MEAKJJMH_01818 8.5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEAKJJMH_01819 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MEAKJJMH_01820 1.1e-26 ylqC S Belongs to the UPF0109 family
MEAKJJMH_01821 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEAKJJMH_01822 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MEAKJJMH_01823 4.4e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
MEAKJJMH_01824 7e-198 yfnA E amino acid
MEAKJJMH_01825 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEAKJJMH_01826 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
MEAKJJMH_01827 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEAKJJMH_01828 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEAKJJMH_01829 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEAKJJMH_01830 1.2e-19 S Tetratricopeptide repeat
MEAKJJMH_01831 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEAKJJMH_01832 1.7e-195 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEAKJJMH_01833 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEAKJJMH_01834 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEAKJJMH_01835 3.3e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEAKJJMH_01836 2.5e-22 ykzG S Belongs to the UPF0356 family
MEAKJJMH_01837 5.5e-25
MEAKJJMH_01838 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEAKJJMH_01839 1.3e-20 1.1.1.27 C L-malate dehydrogenase activity
MEAKJJMH_01841 1.7e-23 yktA S Belongs to the UPF0223 family
MEAKJJMH_01842 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MEAKJJMH_01843 0.0 typA T GTP-binding protein TypA
MEAKJJMH_01844 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MEAKJJMH_01845 7e-115 manY G PTS system
MEAKJJMH_01846 3.3e-148 manN G system, mannose fructose sorbose family IID component
MEAKJJMH_01847 4.3e-100 ftsW D Belongs to the SEDS family
MEAKJJMH_01848 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MEAKJJMH_01849 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MEAKJJMH_01850 1.6e-73 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MEAKJJMH_01851 5.3e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEAKJJMH_01852 4.1e-131 ylbL T Belongs to the peptidase S16 family
MEAKJJMH_01853 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MEAKJJMH_01854 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEAKJJMH_01855 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEAKJJMH_01856 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEAKJJMH_01857 6.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEAKJJMH_01858 9e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MEAKJJMH_01859 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MEAKJJMH_01860 1.9e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MEAKJJMH_01861 7.1e-162 purD 6.3.4.13 F Belongs to the GARS family
MEAKJJMH_01862 7.2e-107 S Acyltransferase family
MEAKJJMH_01863 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEAKJJMH_01864 5e-122 K LysR substrate binding domain
MEAKJJMH_01866 2.2e-20
MEAKJJMH_01867 4.7e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MEAKJJMH_01868 7.5e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
MEAKJJMH_01869 4e-50 comEA L Competence protein ComEA
MEAKJJMH_01870 2e-69 comEB 3.5.4.12 F ComE operon protein 2
MEAKJJMH_01871 1.6e-156 comEC S Competence protein ComEC
MEAKJJMH_01872 7.1e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
MEAKJJMH_01873 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MEAKJJMH_01874 5.6e-136 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MEAKJJMH_01875 2.2e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MEAKJJMH_01876 6.8e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MEAKJJMH_01877 4.3e-228 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MEAKJJMH_01878 2.4e-15 ypmB S Protein conserved in bacteria
MEAKJJMH_01879 9e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MEAKJJMH_01880 5.9e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MEAKJJMH_01881 5.1e-56 dnaD L DnaD domain protein
MEAKJJMH_01882 1.5e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEAKJJMH_01883 2.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEAKJJMH_01884 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEAKJJMH_01885 3e-94 M transferase activity, transferring glycosyl groups
MEAKJJMH_01886 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
MEAKJJMH_01887 7.6e-100 epsJ1 M Glycosyltransferase like family 2
MEAKJJMH_01890 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MEAKJJMH_01891 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MEAKJJMH_01892 3.1e-56 yqeY S YqeY-like protein
MEAKJJMH_01894 3e-68 xerD L Phage integrase, N-terminal SAM-like domain
MEAKJJMH_01895 6.7e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEAKJJMH_01896 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEAKJJMH_01897 1.9e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MEAKJJMH_01898 2e-277 yfmR S ABC transporter, ATP-binding protein
MEAKJJMH_01899 7.5e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEAKJJMH_01900 1.2e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEAKJJMH_01901 8.7e-74 yvgN C Aldo keto reductase
MEAKJJMH_01902 2.8e-33 yvgN C Aldo keto reductase
MEAKJJMH_01903 2.4e-35 K helix_turn_helix, mercury resistance
MEAKJJMH_01904 7.9e-113 S Aldo keto reductase
MEAKJJMH_01906 6.5e-80 ypmR E GDSL-like Lipase/Acylhydrolase
MEAKJJMH_01907 6.3e-52 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MEAKJJMH_01908 3.6e-24 yozE S Belongs to the UPF0346 family
MEAKJJMH_01909 1.4e-132 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MEAKJJMH_01910 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEAKJJMH_01911 1.2e-83 dprA LU DNA protecting protein DprA
MEAKJJMH_01912 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEAKJJMH_01913 2.9e-138 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MEAKJJMH_01914 1.5e-58 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MEAKJJMH_01915 7.5e-205 G PTS system Galactitol-specific IIC component
MEAKJJMH_01916 2.3e-81 K Bacterial regulatory proteins, tetR family
MEAKJJMH_01917 1.5e-129 yjjC V ATPases associated with a variety of cellular activities
MEAKJJMH_01918 1.8e-202 M Exporter of polyketide antibiotics
MEAKJJMH_01919 8.5e-34 cas6 S Pfam:DUF2276
MEAKJJMH_01920 2.8e-209 csm1 S CRISPR-associated protein Csm1 family
MEAKJJMH_01921 2.8e-33 csm2 L Csm2 Type III-A
MEAKJJMH_01922 3.4e-70 csm3 L RAMP superfamily
MEAKJJMH_01923 4e-66 csm4 L CRISPR-associated RAMP protein, Csm4 family
MEAKJJMH_01924 1.4e-46 csm5 L RAMP superfamily
MEAKJJMH_01925 5.6e-11 csm5 L RAMP superfamily
MEAKJJMH_01926 4.9e-88 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEAKJJMH_01927 1.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEAKJJMH_01928 1.1e-71 csm6 S Psort location Cytoplasmic, score
MEAKJJMH_01929 1.1e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MEAKJJMH_01930 2.6e-46 S Repeat protein
MEAKJJMH_01931 3.8e-276 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MEAKJJMH_01933 2.3e-119 L Belongs to the 'phage' integrase family
MEAKJJMH_01934 4.7e-14
MEAKJJMH_01936 4e-09
MEAKJJMH_01940 1.4e-12 M Host cell surface-exposed lipoprotein
MEAKJJMH_01941 5.2e-16 E IrrE N-terminal-like domain
MEAKJJMH_01942 8.8e-26 K Helix-turn-helix XRE-family like proteins
MEAKJJMH_01943 4.6e-15
MEAKJJMH_01944 8e-36 K Phage regulatory protein
MEAKJJMH_01946 5.3e-18 S Domain of unknown function (DUF771)
MEAKJJMH_01950 8.9e-120 L snf2 family
MEAKJJMH_01952 4.1e-18
MEAKJJMH_01953 3.5e-25 L VRR_NUC
MEAKJJMH_01954 9.3e-127 L AAA domain
MEAKJJMH_01955 7e-35 S Protein of unknown function (DUF669)
MEAKJJMH_01956 6.8e-176 polB 2.7.7.7 L DNA polymerase elongation subunit (Family B)
MEAKJJMH_01957 5.5e-158 L Phage plasmid primase, P4 family
MEAKJJMH_01962 4.1e-08
MEAKJJMH_01963 5e-28 S HNH endonuclease
MEAKJJMH_01964 1.7e-59 L Belongs to the 'phage' integrase family
MEAKJJMH_01966 7.3e-70 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
MEAKJJMH_01967 1.8e-100 L Probable transposase
MEAKJJMH_01970 9.3e-18
MEAKJJMH_01972 4.9e-22 L HNH nucleases
MEAKJJMH_01973 5e-33 L Phage terminase, small subunit
MEAKJJMH_01974 2.6e-218 S Terminase
MEAKJJMH_01975 7.9e-105 S Phage portal protein, HK97 family
MEAKJJMH_01976 1.2e-71 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MEAKJJMH_01977 5.6e-94 S Phage capsid family
MEAKJJMH_01978 2.6e-12 L Phage gp6-like head-tail connector protein
MEAKJJMH_01980 2.7e-12 S Bacteriophage HK97-gp10, putative tail-component
MEAKJJMH_01982 2.1e-24 S Phage tail tube protein
MEAKJJMH_01984 1.9e-105 M Phage tail tape measure protein TP901
MEAKJJMH_01985 1.4e-89 S Phage tail protein
MEAKJJMH_01986 8.5e-273 rny D peptidase
MEAKJJMH_01987 2.5e-101 M Prophage endopeptidase tail
MEAKJJMH_01989 1.3e-71 S Domain of unknown function (DUF2479)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)