ORF_ID e_value Gene_name EC_number CAZy COGs Description
NLIFCLDM_00001 9e-30 yqkB S Belongs to the HesB IscA family
NLIFCLDM_00002 3.2e-67 yxkH G Polysaccharide deacetylase
NLIFCLDM_00003 9.6e-09
NLIFCLDM_00004 1.9e-52 K LysR substrate binding domain
NLIFCLDM_00005 1.9e-120 MA20_14895 S Conserved hypothetical protein 698
NLIFCLDM_00006 1.1e-199 nupG F Nucleoside
NLIFCLDM_00007 3.1e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLIFCLDM_00008 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NLIFCLDM_00009 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NLIFCLDM_00010 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NLIFCLDM_00011 8.6e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NLIFCLDM_00012 1.2e-19 yaaA S S4 domain protein YaaA
NLIFCLDM_00013 1.2e-152 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NLIFCLDM_00014 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLIFCLDM_00015 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLIFCLDM_00016 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
NLIFCLDM_00017 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NLIFCLDM_00018 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NLIFCLDM_00019 3.1e-108 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NLIFCLDM_00020 7.3e-117 S Glycosyl transferase family 2
NLIFCLDM_00021 7.4e-64 D peptidase
NLIFCLDM_00022 0.0 asnB 6.3.5.4 E Asparagine synthase
NLIFCLDM_00025 1.1e-130 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NLIFCLDM_00026 1.4e-186 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NLIFCLDM_00027 4.1e-158 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NLIFCLDM_00028 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NLIFCLDM_00029 2.8e-118 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NLIFCLDM_00031 1.6e-55 ctsR K Belongs to the CtsR family
NLIFCLDM_00032 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NLIFCLDM_00033 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLIFCLDM_00034 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLIFCLDM_00035 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
NLIFCLDM_00036 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NLIFCLDM_00037 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NLIFCLDM_00038 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NLIFCLDM_00039 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NLIFCLDM_00040 1.2e-89 patB 4.4.1.8 E Aminotransferase, class I
NLIFCLDM_00041 2.5e-113 K response regulator
NLIFCLDM_00042 1.7e-141 hpk31 2.7.13.3 T Histidine kinase
NLIFCLDM_00043 1.5e-89 lacX 5.1.3.3 G Aldose 1-epimerase
NLIFCLDM_00044 5.1e-146 G Transporter, major facilitator family protein
NLIFCLDM_00045 2.6e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NLIFCLDM_00046 1.2e-245 yhcA V ABC transporter, ATP-binding protein
NLIFCLDM_00047 5.8e-35 K Bacterial regulatory proteins, tetR family
NLIFCLDM_00048 3.4e-223 lmrA V ABC transporter, ATP-binding protein
NLIFCLDM_00049 8.2e-252 yfiC V ABC transporter
NLIFCLDM_00051 2.7e-37 yjcF K protein acetylation
NLIFCLDM_00052 1.4e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
NLIFCLDM_00053 8.7e-72 lemA S LemA family
NLIFCLDM_00054 1.3e-114 htpX O Belongs to the peptidase M48B family
NLIFCLDM_00056 8.8e-272 helD 3.6.4.12 L DNA helicase
NLIFCLDM_00057 3.5e-127 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLIFCLDM_00058 2.3e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLIFCLDM_00059 8.8e-101 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NLIFCLDM_00060 8.4e-83 ybhF_2 V abc transporter atp-binding protein
NLIFCLDM_00061 7.8e-104 ybhR V ABC transporter
NLIFCLDM_00062 3.9e-31 K Bacterial regulatory proteins, tetR family
NLIFCLDM_00063 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
NLIFCLDM_00064 7.3e-151 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NLIFCLDM_00065 5.1e-128
NLIFCLDM_00066 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLIFCLDM_00067 6.3e-105 tatD L hydrolase, TatD family
NLIFCLDM_00068 4.5e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NLIFCLDM_00069 5.4e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NLIFCLDM_00070 1.2e-22 veg S Biofilm formation stimulator VEG
NLIFCLDM_00071 2.8e-90 S Alpha/beta hydrolase of unknown function (DUF915)
NLIFCLDM_00072 7.2e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
NLIFCLDM_00073 6.6e-46 argR K Regulates arginine biosynthesis genes
NLIFCLDM_00074 3.7e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NLIFCLDM_00075 6.7e-155 amtB P ammonium transporter
NLIFCLDM_00077 1.9e-89 sip L Belongs to the 'phage' integrase family
NLIFCLDM_00078 5e-32 S ParE toxin of type II toxin-antitoxin system, parDE
NLIFCLDM_00079 9.7e-23
NLIFCLDM_00081 4.7e-76
NLIFCLDM_00082 1e-09
NLIFCLDM_00084 1.1e-40 XK27_10050 K Peptidase S24-like
NLIFCLDM_00086 3.1e-17
NLIFCLDM_00088 3.6e-23 K Cro/C1-type HTH DNA-binding domain
NLIFCLDM_00091 7.1e-13 cro K Helix-turn-helix XRE-family like proteins
NLIFCLDM_00092 6.7e-59 kilA K BRO family, N-terminal domain
NLIFCLDM_00098 9.8e-55 S Putative HNHc nuclease
NLIFCLDM_00099 8.6e-30 S Phage replisome organizer, N-terminal domain protein
NLIFCLDM_00102 1.6e-25
NLIFCLDM_00103 2.2e-70
NLIFCLDM_00117 1.2e-34 arpU S Phage transcriptional regulator, ArpU family
NLIFCLDM_00118 9.4e-41 gepA S Protein of unknown function (DUF4065)
NLIFCLDM_00119 2.9e-47
NLIFCLDM_00120 5.2e-12
NLIFCLDM_00123 1.3e-85 L HNH nucleases
NLIFCLDM_00124 1.6e-79 L Phage terminase, small subunit
NLIFCLDM_00125 0.0 S Phage Terminase
NLIFCLDM_00127 3.7e-197 S Phage portal protein
NLIFCLDM_00128 9.1e-114 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NLIFCLDM_00129 6e-195 S Phage capsid family
NLIFCLDM_00130 2.8e-22 S Phage gp6-like head-tail connector protein
NLIFCLDM_00131 3.9e-49 S Phage head-tail joining protein
NLIFCLDM_00132 1.4e-53 S Bacteriophage HK97-gp10, putative tail-component
NLIFCLDM_00133 3e-55 S Protein of unknown function (DUF806)
NLIFCLDM_00134 3.5e-78 S Phage tail tube protein
NLIFCLDM_00135 1.7e-16 S Phage tail assembly chaperone proteins, TAC
NLIFCLDM_00137 3.8e-296 M Phage tail tape measure protein TP901
NLIFCLDM_00138 3.5e-77 S Phage tail protein
NLIFCLDM_00139 7.2e-120 rny D peptidase
NLIFCLDM_00141 3.7e-72 S Domain of unknown function (DUF2479)
NLIFCLDM_00147 1.8e-130 M Glycosyl hydrolases family 25
NLIFCLDM_00148 2.2e-201 argH 4.3.2.1 E argininosuccinate lyase
NLIFCLDM_00149 4.2e-196 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NLIFCLDM_00150 1.5e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NLIFCLDM_00151 4.4e-127 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLIFCLDM_00152 3.6e-103 pfoS S Phosphotransferase system, EIIC
NLIFCLDM_00154 3e-128 2.4.1.9 GH68 M MucBP domain
NLIFCLDM_00155 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NLIFCLDM_00156 7.4e-52 adhR K helix_turn_helix, mercury resistance
NLIFCLDM_00157 9e-137 purR 2.4.2.7 F pur operon repressor
NLIFCLDM_00158 5.6e-39 EGP Transmembrane secretion effector
NLIFCLDM_00159 2.3e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NLIFCLDM_00160 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLIFCLDM_00161 4.5e-19 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLIFCLDM_00162 5.8e-112 dkg S reductase
NLIFCLDM_00163 1.7e-24
NLIFCLDM_00164 2.7e-11 2.4.2.3 F Phosphorylase superfamily
NLIFCLDM_00165 6.8e-32 2.4.2.3 F Phosphorylase superfamily
NLIFCLDM_00166 1.4e-290 ybiT S ABC transporter, ATP-binding protein
NLIFCLDM_00167 9.5e-21 ytkL S Beta-lactamase superfamily domain
NLIFCLDM_00168 1.4e-33 ytkL S Belongs to the UPF0173 family
NLIFCLDM_00169 3.8e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NLIFCLDM_00170 1.1e-126 S overlaps another CDS with the same product name
NLIFCLDM_00171 3.8e-86 S overlaps another CDS with the same product name
NLIFCLDM_00172 1.9e-55 spoVK O ATPase family associated with various cellular activities (AAA)
NLIFCLDM_00173 7.8e-23
NLIFCLDM_00174 5.4e-39 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
NLIFCLDM_00176 7.7e-64
NLIFCLDM_00177 4.5e-105 ydcZ S Putative inner membrane exporter, YdcZ
NLIFCLDM_00178 5.8e-88 S hydrolase
NLIFCLDM_00179 3.3e-205 ywfO S HD domain protein
NLIFCLDM_00180 1.3e-85 yfeJ 6.3.5.2 F glutamine amidotransferase
NLIFCLDM_00181 1.8e-32 ywiB S Domain of unknown function (DUF1934)
NLIFCLDM_00182 9.8e-42 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NLIFCLDM_00183 3.6e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NLIFCLDM_00186 5.1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLIFCLDM_00187 1.2e-188 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NLIFCLDM_00188 3.6e-41 rpmE2 J Ribosomal protein L31
NLIFCLDM_00189 1.8e-60
NLIFCLDM_00190 9.9e-258 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
NLIFCLDM_00192 9.4e-80 S Cell surface protein
NLIFCLDM_00194 1.6e-180 pbuG S permease
NLIFCLDM_00195 3.9e-46 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLIFCLDM_00196 1.1e-33 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLIFCLDM_00198 6.5e-60 M ErfK YbiS YcfS YnhG
NLIFCLDM_00199 5.8e-66 S Uncharacterized protein conserved in bacteria (DUF2263)
NLIFCLDM_00200 1.8e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NLIFCLDM_00201 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NLIFCLDM_00202 2.1e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NLIFCLDM_00203 3.7e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLIFCLDM_00204 5.4e-13
NLIFCLDM_00205 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
NLIFCLDM_00206 9.7e-91 yunF F Protein of unknown function DUF72
NLIFCLDM_00207 1.9e-155 nrnB S DHHA1 domain
NLIFCLDM_00208 8.2e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NLIFCLDM_00209 7.6e-60
NLIFCLDM_00210 2.3e-48 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
NLIFCLDM_00211 5.9e-22 S Cytochrome B5
NLIFCLDM_00212 3.1e-19 sigH K DNA-templated transcription, initiation
NLIFCLDM_00213 1.1e-67 recX 2.4.1.337 GT4 S Regulatory protein RecX
NLIFCLDM_00214 2.1e-191 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLIFCLDM_00215 2.6e-97 ygaC J Belongs to the UPF0374 family
NLIFCLDM_00216 6.9e-92 yueF S AI-2E family transporter
NLIFCLDM_00217 6.5e-158 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NLIFCLDM_00218 1.8e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NLIFCLDM_00219 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NLIFCLDM_00220 0.0 lacL 3.2.1.23 G -beta-galactosidase
NLIFCLDM_00221 6.8e-289 lacS G Transporter
NLIFCLDM_00222 5.9e-111 galR K Transcriptional regulator
NLIFCLDM_00223 1.2e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NLIFCLDM_00224 6.6e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NLIFCLDM_00225 3.8e-199 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NLIFCLDM_00226 0.0 rafA 3.2.1.22 G alpha-galactosidase
NLIFCLDM_00227 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NLIFCLDM_00228 1.5e-22 XK27_09445 S Domain of unknown function (DUF1827)
NLIFCLDM_00229 0.0 clpE O Belongs to the ClpA ClpB family
NLIFCLDM_00230 1.5e-15
NLIFCLDM_00231 9.7e-37 ptsH G phosphocarrier protein HPR
NLIFCLDM_00232 4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLIFCLDM_00233 1.3e-160 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NLIFCLDM_00234 1.2e-127 cpoA GT4 M Glycosyltransferase, group 1 family protein
NLIFCLDM_00235 1.5e-130 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLIFCLDM_00236 1.5e-25 ykuJ S Protein of unknown function (DUF1797)
NLIFCLDM_00237 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NLIFCLDM_00242 5.1e-08
NLIFCLDM_00248 6.1e-07
NLIFCLDM_00249 3.9e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NLIFCLDM_00250 1.7e-54 rplI J Binds to the 23S rRNA
NLIFCLDM_00251 3.6e-207 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NLIFCLDM_00252 4e-64 C FMN binding
NLIFCLDM_00256 1.1e-218 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NLIFCLDM_00257 2.1e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NLIFCLDM_00258 1.8e-66 coiA 3.6.4.12 S Competence protein
NLIFCLDM_00259 9.6e-232 pepF E oligoendopeptidase F
NLIFCLDM_00260 1.3e-41 yjbH Q Thioredoxin
NLIFCLDM_00261 1.1e-97 pstS P Phosphate
NLIFCLDM_00262 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
NLIFCLDM_00263 5.1e-122 pstA P Phosphate transport system permease protein PstA
NLIFCLDM_00264 2.7e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLIFCLDM_00265 6.7e-115 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLIFCLDM_00266 2.7e-56 P Plays a role in the regulation of phosphate uptake
NLIFCLDM_00267 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NLIFCLDM_00268 1.1e-79 S VIT family
NLIFCLDM_00269 9.4e-84 S membrane
NLIFCLDM_00270 1.2e-17 M1-874 K Domain of unknown function (DUF1836)
NLIFCLDM_00271 5.2e-65 hly S protein, hemolysin III
NLIFCLDM_00272 2.1e-34 K helix_turn_helix, Arsenical Resistance Operon Repressor
NLIFCLDM_00273 5.9e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLIFCLDM_00276 3e-14
NLIFCLDM_00277 4e-68 L PFAM Integrase catalytic region
NLIFCLDM_00278 3.2e-20 L Helix-turn-helix domain
NLIFCLDM_00279 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NLIFCLDM_00280 1.3e-158 ccpA K catabolite control protein A
NLIFCLDM_00281 3.7e-42 S VanZ like family
NLIFCLDM_00282 1.5e-119 yebC K Transcriptional regulatory protein
NLIFCLDM_00283 4.6e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLIFCLDM_00284 6.2e-121 comGA NU Type II IV secretion system protein
NLIFCLDM_00285 5.7e-98 comGB NU type II secretion system
NLIFCLDM_00286 1.2e-27 comGC U competence protein ComGC
NLIFCLDM_00287 1.9e-13
NLIFCLDM_00289 5.5e-11 S Putative Competence protein ComGF
NLIFCLDM_00291 9.9e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
NLIFCLDM_00292 1.6e-183 cycA E Amino acid permease
NLIFCLDM_00293 3e-57 S Calcineurin-like phosphoesterase
NLIFCLDM_00294 4.3e-53 yutD S Protein of unknown function (DUF1027)
NLIFCLDM_00295 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NLIFCLDM_00296 7.8e-32 S Protein of unknown function (DUF1461)
NLIFCLDM_00297 1.5e-91 dedA S SNARE associated Golgi protein
NLIFCLDM_00298 5.5e-96 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NLIFCLDM_00299 8.8e-50 yugI 5.3.1.9 J general stress protein
NLIFCLDM_00301 2.1e-07
NLIFCLDM_00306 1.4e-175 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NLIFCLDM_00307 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLIFCLDM_00308 6.8e-21 cycA E Amino acid permease
NLIFCLDM_00309 3.5e-163 cycA E Amino acid permease
NLIFCLDM_00310 4.1e-186 ytgP S Polysaccharide biosynthesis protein
NLIFCLDM_00311 1.5e-60 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLIFCLDM_00312 4.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NLIFCLDM_00313 1.1e-192 pepV 3.5.1.18 E dipeptidase PepV
NLIFCLDM_00314 3.3e-182 S Protein of unknown function DUF262
NLIFCLDM_00316 4e-36
NLIFCLDM_00317 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NLIFCLDM_00318 4.2e-61 marR K Transcriptional regulator, MarR family
NLIFCLDM_00319 4.9e-102 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLIFCLDM_00320 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLIFCLDM_00321 1.5e-103 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NLIFCLDM_00322 3.2e-98 IQ reductase
NLIFCLDM_00323 2.1e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NLIFCLDM_00324 1.2e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NLIFCLDM_00325 3.9e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NLIFCLDM_00326 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NLIFCLDM_00327 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NLIFCLDM_00328 8.8e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NLIFCLDM_00329 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NLIFCLDM_00330 5.6e-230 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NLIFCLDM_00331 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
NLIFCLDM_00332 3.9e-301 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NLIFCLDM_00333 5.7e-119 gla U Major intrinsic protein
NLIFCLDM_00334 5.8e-45 ykuL S CBS domain
NLIFCLDM_00335 1.5e-60 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NLIFCLDM_00336 4.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NLIFCLDM_00337 1.5e-86 ykuT M mechanosensitive ion channel
NLIFCLDM_00340 3.9e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLIFCLDM_00341 2e-21 yheA S Belongs to the UPF0342 family
NLIFCLDM_00342 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
NLIFCLDM_00343 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NLIFCLDM_00345 5.4e-53 hit FG histidine triad
NLIFCLDM_00346 9.8e-95 ecsA V ABC transporter, ATP-binding protein
NLIFCLDM_00347 3.5e-70 ecsB U ABC transporter
NLIFCLDM_00348 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
NLIFCLDM_00349 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NLIFCLDM_00350 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NLIFCLDM_00351 2.3e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLIFCLDM_00352 3.8e-238 sftA D Belongs to the FtsK SpoIIIE SftA family
NLIFCLDM_00353 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NLIFCLDM_00354 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
NLIFCLDM_00355 6.7e-69 ybhL S Belongs to the BI1 family
NLIFCLDM_00356 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLIFCLDM_00357 3.3e-107 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NLIFCLDM_00358 2.7e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NLIFCLDM_00359 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NLIFCLDM_00360 1.6e-79 dnaB L replication initiation and membrane attachment
NLIFCLDM_00361 2.8e-107 dnaI L Primosomal protein DnaI
NLIFCLDM_00362 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NLIFCLDM_00363 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NLIFCLDM_00364 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NLIFCLDM_00365 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NLIFCLDM_00366 1.9e-71 yqeG S HAD phosphatase, family IIIA
NLIFCLDM_00367 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
NLIFCLDM_00368 1e-29 yhbY J RNA-binding protein
NLIFCLDM_00369 1.6e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NLIFCLDM_00370 4.7e-71 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NLIFCLDM_00371 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NLIFCLDM_00372 4.2e-82 H Nodulation protein S (NodS)
NLIFCLDM_00373 1.3e-122 ylbM S Belongs to the UPF0348 family
NLIFCLDM_00374 2e-57 yceD S Uncharacterized ACR, COG1399
NLIFCLDM_00375 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NLIFCLDM_00376 7.5e-88 plsC 2.3.1.51 I Acyltransferase
NLIFCLDM_00377 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
NLIFCLDM_00378 1.5e-27 yazA L GIY-YIG catalytic domain protein
NLIFCLDM_00379 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
NLIFCLDM_00380 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NLIFCLDM_00381 6.9e-37
NLIFCLDM_00382 1.5e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NLIFCLDM_00383 1.8e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NLIFCLDM_00384 1.4e-158 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NLIFCLDM_00385 7.9e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NLIFCLDM_00386 6e-108 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NLIFCLDM_00388 3.1e-111 K response regulator
NLIFCLDM_00389 1.2e-165 arlS 2.7.13.3 T Histidine kinase
NLIFCLDM_00390 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLIFCLDM_00391 1.8e-22 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NLIFCLDM_00392 4e-135 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NLIFCLDM_00393 7.3e-105
NLIFCLDM_00394 5.5e-117
NLIFCLDM_00395 1.3e-41 dut S dUTPase
NLIFCLDM_00396 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLIFCLDM_00397 3.7e-46 yqhY S Asp23 family, cell envelope-related function
NLIFCLDM_00398 5.5e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NLIFCLDM_00399 2.3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NLIFCLDM_00400 1.2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLIFCLDM_00401 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLIFCLDM_00402 6.1e-83 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NLIFCLDM_00403 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NLIFCLDM_00404 6.6e-49 argR K Regulates arginine biosynthesis genes
NLIFCLDM_00405 9.3e-178 recN L May be involved in recombinational repair of damaged DNA
NLIFCLDM_00406 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NLIFCLDM_00407 2.2e-30 ynzC S UPF0291 protein
NLIFCLDM_00408 5.9e-27 yneF S UPF0154 protein
NLIFCLDM_00409 2.3e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
NLIFCLDM_00410 1.6e-43 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NLIFCLDM_00411 2.7e-74 yciQ P membrane protein (DUF2207)
NLIFCLDM_00412 4.6e-20 D nuclear chromosome segregation
NLIFCLDM_00413 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NLIFCLDM_00414 8.7e-40 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NLIFCLDM_00415 2.8e-69 gluP 3.4.21.105 S Peptidase, S54 family
NLIFCLDM_00416 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
NLIFCLDM_00417 4.7e-158 glk 2.7.1.2 G Glucokinase
NLIFCLDM_00418 4e-45 yqhL P Rhodanese-like protein
NLIFCLDM_00419 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
NLIFCLDM_00420 5.4e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NLIFCLDM_00421 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
NLIFCLDM_00422 1.7e-45 glnR K Transcriptional regulator
NLIFCLDM_00423 2e-247 glnA 6.3.1.2 E glutamine synthetase
NLIFCLDM_00425 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NLIFCLDM_00426 2.7e-48 S Domain of unknown function (DUF956)
NLIFCLDM_00427 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NLIFCLDM_00428 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NLIFCLDM_00429 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLIFCLDM_00430 1.1e-101 cdsA 2.7.7.41 S Belongs to the CDS family
NLIFCLDM_00431 3.4e-156 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NLIFCLDM_00432 2.5e-258 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NLIFCLDM_00433 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLIFCLDM_00434 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
NLIFCLDM_00435 4.8e-170 nusA K Participates in both transcription termination and antitermination
NLIFCLDM_00436 1.4e-39 ylxR K Protein of unknown function (DUF448)
NLIFCLDM_00437 6.9e-26 ylxQ J ribosomal protein
NLIFCLDM_00438 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NLIFCLDM_00439 3.7e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NLIFCLDM_00440 2.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NLIFCLDM_00441 5.1e-96 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NLIFCLDM_00442 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NLIFCLDM_00443 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NLIFCLDM_00444 1.5e-274 dnaK O Heat shock 70 kDa protein
NLIFCLDM_00445 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NLIFCLDM_00446 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NLIFCLDM_00448 4.6e-205 glnP P ABC transporter
NLIFCLDM_00449 4.4e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NLIFCLDM_00450 1.5e-31
NLIFCLDM_00451 4.1e-112 ampC V Beta-lactamase
NLIFCLDM_00452 2.1e-60 yiiE S Protein of unknown function (DUF1211)
NLIFCLDM_00453 1.6e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NLIFCLDM_00454 1.9e-83 L hmm pf00665
NLIFCLDM_00455 1.9e-52 L Helix-turn-helix domain
NLIFCLDM_00456 2.7e-110 cobQ S glutamine amidotransferase
NLIFCLDM_00457 2.3e-219 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NLIFCLDM_00458 6.8e-86 tdk 2.7.1.21 F thymidine kinase
NLIFCLDM_00459 2.1e-178 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NLIFCLDM_00460 4.1e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NLIFCLDM_00461 4.5e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NLIFCLDM_00462 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NLIFCLDM_00463 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
NLIFCLDM_00464 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLIFCLDM_00465 9.9e-41 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NLIFCLDM_00466 7e-58 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLIFCLDM_00467 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NLIFCLDM_00468 3.9e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NLIFCLDM_00469 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NLIFCLDM_00470 3e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NLIFCLDM_00471 4.1e-15 ywzB S Protein of unknown function (DUF1146)
NLIFCLDM_00472 2.7e-196 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLIFCLDM_00473 3.4e-167 mbl D Cell shape determining protein MreB Mrl
NLIFCLDM_00474 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NLIFCLDM_00475 1.3e-13 S Protein of unknown function (DUF2969)
NLIFCLDM_00476 6.1e-187 rodA D Belongs to the SEDS family
NLIFCLDM_00477 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
NLIFCLDM_00478 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
NLIFCLDM_00479 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NLIFCLDM_00480 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NLIFCLDM_00481 3.7e-120 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NLIFCLDM_00482 2.1e-287 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NLIFCLDM_00483 1.3e-139 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLIFCLDM_00484 3.4e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NLIFCLDM_00485 3.3e-90 stp 3.1.3.16 T phosphatase
NLIFCLDM_00486 3.4e-191 KLT serine threonine protein kinase
NLIFCLDM_00487 3.1e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NLIFCLDM_00488 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
NLIFCLDM_00489 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NLIFCLDM_00490 4.5e-53 asp S Asp23 family, cell envelope-related function
NLIFCLDM_00491 1.3e-238 yloV S DAK2 domain fusion protein YloV
NLIFCLDM_00492 1.8e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NLIFCLDM_00493 6e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NLIFCLDM_00494 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLIFCLDM_00495 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NLIFCLDM_00496 3.2e-212 smc D Required for chromosome condensation and partitioning
NLIFCLDM_00497 6.1e-145 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NLIFCLDM_00498 1.2e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NLIFCLDM_00499 8.5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NLIFCLDM_00500 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NLIFCLDM_00501 1.1e-26 ylqC S Belongs to the UPF0109 family
NLIFCLDM_00502 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NLIFCLDM_00503 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NLIFCLDM_00504 4.4e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
NLIFCLDM_00505 2.6e-197 yfnA E amino acid
NLIFCLDM_00506 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NLIFCLDM_00507 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
NLIFCLDM_00508 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NLIFCLDM_00509 2e-115 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLIFCLDM_00510 9.9e-268 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLIFCLDM_00511 6.1e-19 S Tetratricopeptide repeat
NLIFCLDM_00512 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NLIFCLDM_00513 6e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NLIFCLDM_00514 1.7e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NLIFCLDM_00515 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NLIFCLDM_00516 2.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLIFCLDM_00517 4.2e-22 ykzG S Belongs to the UPF0356 family
NLIFCLDM_00518 5.5e-25
NLIFCLDM_00519 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NLIFCLDM_00520 3.1e-31 1.1.1.27 C L-malate dehydrogenase activity
NLIFCLDM_00521 1.7e-23 yktA S Belongs to the UPF0223 family
NLIFCLDM_00522 1.3e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NLIFCLDM_00523 0.0 typA T GTP-binding protein TypA
NLIFCLDM_00524 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NLIFCLDM_00525 7e-115 manY G PTS system
NLIFCLDM_00526 3.3e-148 manN G system, mannose fructose sorbose family IID component
NLIFCLDM_00527 3e-101 ftsW D Belongs to the SEDS family
NLIFCLDM_00528 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NLIFCLDM_00529 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NLIFCLDM_00530 5.5e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NLIFCLDM_00531 5.3e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NLIFCLDM_00532 4.1e-131 ylbL T Belongs to the peptidase S16 family
NLIFCLDM_00533 3.8e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NLIFCLDM_00534 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLIFCLDM_00535 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLIFCLDM_00536 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLIFCLDM_00537 6.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NLIFCLDM_00538 6.9e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NLIFCLDM_00539 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NLIFCLDM_00540 1.1e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NLIFCLDM_00541 2.1e-161 purD 6.3.4.13 F Belongs to the GARS family
NLIFCLDM_00542 5.9e-109 S Acyltransferase family
NLIFCLDM_00543 3.7e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLIFCLDM_00544 3.9e-122 K LysR substrate binding domain
NLIFCLDM_00546 2.2e-20
NLIFCLDM_00547 8.1e-53 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NLIFCLDM_00548 1.7e-267 argS 6.1.1.19 J Arginyl-tRNA synthetase
NLIFCLDM_00549 1.7e-48 comEA L Competence protein ComEA
NLIFCLDM_00550 2e-69 comEB 3.5.4.12 F ComE operon protein 2
NLIFCLDM_00551 4.7e-156 comEC S Competence protein ComEC
NLIFCLDM_00552 3e-102 holA 2.7.7.7 L DNA polymerase III delta subunit
NLIFCLDM_00553 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NLIFCLDM_00554 6.7e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NLIFCLDM_00555 1.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NLIFCLDM_00556 2.8e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NLIFCLDM_00557 4.8e-227 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NLIFCLDM_00558 4.2e-33 ypmB S Protein conserved in bacteria
NLIFCLDM_00559 1.4e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NLIFCLDM_00560 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NLIFCLDM_00561 7.2e-55 dnaD L DnaD domain protein
NLIFCLDM_00562 2.2e-82 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NLIFCLDM_00563 7.6e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLIFCLDM_00564 1.3e-125 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NLIFCLDM_00565 3e-94 M transferase activity, transferring glycosyl groups
NLIFCLDM_00566 2.8e-84 M Glycosyltransferase sugar-binding region containing DXD motif
NLIFCLDM_00567 4.4e-100 epsJ1 M Glycosyltransferase like family 2
NLIFCLDM_00570 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NLIFCLDM_00571 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NLIFCLDM_00572 4e-47 yqeY S YqeY-like protein
NLIFCLDM_00574 1.3e-68 xerD L Phage integrase, N-terminal SAM-like domain
NLIFCLDM_00575 1.3e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NLIFCLDM_00576 8.2e-108 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NLIFCLDM_00577 4.3e-132 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NLIFCLDM_00578 3.6e-274 yfmR S ABC transporter, ATP-binding protein
NLIFCLDM_00579 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NLIFCLDM_00580 1.6e-56 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NLIFCLDM_00582 1.1e-79 ypmR E GDSL-like Lipase/Acylhydrolase
NLIFCLDM_00583 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NLIFCLDM_00584 3.6e-24 yozE S Belongs to the UPF0346 family
NLIFCLDM_00585 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NLIFCLDM_00586 5.4e-96 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLIFCLDM_00587 1.1e-84 dprA LU DNA protecting protein DprA
NLIFCLDM_00588 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLIFCLDM_00589 5.6e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NLIFCLDM_00590 9.8e-205 G PTS system Galactitol-specific IIC component
NLIFCLDM_00591 1e-81 K Bacterial regulatory proteins, tetR family
NLIFCLDM_00592 2.3e-130 yjjC V ATPases associated with a variety of cellular activities
NLIFCLDM_00593 1.1e-204 M Exporter of polyketide antibiotics
NLIFCLDM_00594 5e-34 cas6 S Pfam:DUF2276
NLIFCLDM_00595 4.5e-207 csm1 S CRISPR-associated protein Csm1 family
NLIFCLDM_00596 2.8e-33 csm2 L Csm2 Type III-A
NLIFCLDM_00597 2.6e-70 csm3 L RAMP superfamily
NLIFCLDM_00598 4e-66 csm4 L CRISPR-associated RAMP protein, Csm4 family
NLIFCLDM_00599 2.9e-70 csm5 L RAMP superfamily
NLIFCLDM_00600 5.4e-87 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLIFCLDM_00601 1.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLIFCLDM_00602 7.4e-71 csm6 S Psort location Cytoplasmic, score
NLIFCLDM_00603 1.1e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NLIFCLDM_00604 7.6e-46 S Repeat protein
NLIFCLDM_00605 1.7e-276 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NLIFCLDM_00606 6.1e-14
NLIFCLDM_00610 1.3e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLIFCLDM_00611 5.5e-68 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NLIFCLDM_00612 9.1e-43 yodB K Transcriptional regulator, HxlR family
NLIFCLDM_00613 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NLIFCLDM_00614 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLIFCLDM_00615 1.5e-126 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NLIFCLDM_00616 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
NLIFCLDM_00617 1.7e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLIFCLDM_00618 6.4e-12
NLIFCLDM_00619 2.3e-144 iunH2 3.2.2.1 F nucleoside hydrolase
NLIFCLDM_00620 7.6e-43 XK27_03960 S Protein of unknown function (DUF3013)
NLIFCLDM_00621 1e-108 prmA J Ribosomal protein L11 methyltransferase
NLIFCLDM_00622 3.1e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NLIFCLDM_00623 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLIFCLDM_00624 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NLIFCLDM_00625 1.1e-56 3.1.3.18 J HAD-hyrolase-like
NLIFCLDM_00626 2.9e-41 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NLIFCLDM_00627 5.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLIFCLDM_00628 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NLIFCLDM_00629 2.7e-204 pyrP F Permease
NLIFCLDM_00630 4.3e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NLIFCLDM_00631 3.2e-190 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NLIFCLDM_00632 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NLIFCLDM_00633 1e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLIFCLDM_00634 6.3e-134 K Transcriptional regulator
NLIFCLDM_00635 8.3e-144 ppaC 3.6.1.1 C inorganic pyrophosphatase
NLIFCLDM_00636 8.6e-115 glcR K DeoR C terminal sensor domain
NLIFCLDM_00637 1.2e-171 patA 2.6.1.1 E Aminotransferase
NLIFCLDM_00638 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NLIFCLDM_00640 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NLIFCLDM_00641 6.1e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NLIFCLDM_00642 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
NLIFCLDM_00643 5e-23 S Family of unknown function (DUF5322)
NLIFCLDM_00644 1e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NLIFCLDM_00645 8.8e-38
NLIFCLDM_00649 1.1e-18 D nuclear chromosome segregation
NLIFCLDM_00651 9.6e-149 EGP Sugar (and other) transporter
NLIFCLDM_00652 7.8e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
NLIFCLDM_00653 1.3e-103 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NLIFCLDM_00654 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NLIFCLDM_00655 4.6e-72 alkD L DNA alkylation repair enzyme
NLIFCLDM_00656 3.8e-136 EG EamA-like transporter family
NLIFCLDM_00657 3.6e-150 S Tetratricopeptide repeat protein
NLIFCLDM_00658 4.1e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
NLIFCLDM_00659 8.1e-297 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NLIFCLDM_00660 4.3e-116 corA P CorA-like Mg2+ transporter protein
NLIFCLDM_00661 1.9e-160 nhaC C Na H antiporter NhaC
NLIFCLDM_00662 7.2e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NLIFCLDM_00663 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NLIFCLDM_00665 4.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NLIFCLDM_00666 9.9e-155 iscS 2.8.1.7 E Aminotransferase class V
NLIFCLDM_00667 3.7e-41 XK27_04120 S Putative amino acid metabolism
NLIFCLDM_00668 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NLIFCLDM_00669 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NLIFCLDM_00670 4.3e-15 S Protein of unknown function (DUF2929)
NLIFCLDM_00671 0.0 dnaE 2.7.7.7 L DNA polymerase
NLIFCLDM_00672 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NLIFCLDM_00673 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NLIFCLDM_00675 1e-39 ypaA S Protein of unknown function (DUF1304)
NLIFCLDM_00676 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NLIFCLDM_00677 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLIFCLDM_00678 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLIFCLDM_00679 9.4e-202 FbpA K Fibronectin-binding protein
NLIFCLDM_00680 3.1e-40 K Transcriptional regulator
NLIFCLDM_00681 4.8e-117 degV S EDD domain protein, DegV family
NLIFCLDM_00682 7.8e-71 lepB 3.4.21.89 U Signal peptidase, peptidase S26
NLIFCLDM_00683 8.4e-41 6.3.3.2 S ASCH
NLIFCLDM_00684 4.4e-188 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NLIFCLDM_00685 1.7e-79 yjjH S Calcineurin-like phosphoesterase
NLIFCLDM_00686 1.8e-95 EG EamA-like transporter family
NLIFCLDM_00687 1.8e-55 natB CP ABC-2 family transporter protein
NLIFCLDM_00688 7.4e-25 natB CP ABC-type Na efflux pump, permease component
NLIFCLDM_00689 1.1e-111 natA S Domain of unknown function (DUF4162)
NLIFCLDM_00690 3.1e-22 K Acetyltransferase (GNAT) domain
NLIFCLDM_00692 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NLIFCLDM_00693 3.8e-227 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NLIFCLDM_00694 3e-170 rpsA 1.17.7.4 J Ribosomal protein S1
NLIFCLDM_00695 4.8e-59 arsC 1.20.4.1 T Low molecular weight phosphatase family
NLIFCLDM_00696 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NLIFCLDM_00697 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLIFCLDM_00698 1.7e-173 dltB M MBOAT, membrane-bound O-acyltransferase family
NLIFCLDM_00699 4.5e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLIFCLDM_00700 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
NLIFCLDM_00701 5.9e-90 recO L Involved in DNA repair and RecF pathway recombination
NLIFCLDM_00702 4.6e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NLIFCLDM_00703 3.6e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NLIFCLDM_00704 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NLIFCLDM_00705 7.8e-153 phoH T phosphate starvation-inducible protein PhoH
NLIFCLDM_00706 2e-83 lytH 3.5.1.28 M Ami_3
NLIFCLDM_00707 2e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NLIFCLDM_00708 7.7e-12 M Lysin motif
NLIFCLDM_00709 7.9e-125 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NLIFCLDM_00710 1.9e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
NLIFCLDM_00711 3.8e-221 mntH P H( )-stimulated, divalent metal cation uptake system
NLIFCLDM_00712 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
NLIFCLDM_00713 1.7e-118 ica2 GT2 M Glycosyl transferase family group 2
NLIFCLDM_00714 8.3e-44
NLIFCLDM_00715 1.2e-91 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NLIFCLDM_00717 3.1e-185 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NLIFCLDM_00718 5.3e-214 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NLIFCLDM_00719 1.5e-281 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NLIFCLDM_00720 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NLIFCLDM_00721 1.7e-109 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
NLIFCLDM_00722 3.3e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLIFCLDM_00723 3.3e-97 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
NLIFCLDM_00724 1.3e-84 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NLIFCLDM_00725 3.6e-131 L Belongs to the 'phage' integrase family
NLIFCLDM_00726 2e-42 3.1.21.3 V Type I restriction modification DNA specificity domain
NLIFCLDM_00727 3.2e-204 hsdM 2.1.1.72 V type I restriction-modification system
NLIFCLDM_00728 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NLIFCLDM_00730 3.3e-80 XK27_07525 3.6.1.55 F Hydrolase, nudix family
NLIFCLDM_00731 5.7e-57 3.6.1.27 I Acid phosphatase homologues
NLIFCLDM_00732 1.8e-68 maa 2.3.1.79 S Maltose acetyltransferase
NLIFCLDM_00733 9.7e-74 2.3.1.178 M GNAT acetyltransferase
NLIFCLDM_00735 5e-08 XK27_10540 S ParE toxin of type II toxin-antitoxin system, parDE
NLIFCLDM_00736 1e-08 D Antitoxin Phd_YefM, type II toxin-antitoxin system
NLIFCLDM_00737 6.5e-198 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NLIFCLDM_00738 6e-65 ypsA S Belongs to the UPF0398 family
NLIFCLDM_00739 1.4e-187 nhaC C Na H antiporter NhaC
NLIFCLDM_00740 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NLIFCLDM_00741 9.3e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NLIFCLDM_00742 3.6e-112 xerD D recombinase XerD
NLIFCLDM_00743 4.8e-125 cvfB S S1 domain
NLIFCLDM_00744 4.1e-51 yeaL S Protein of unknown function (DUF441)
NLIFCLDM_00745 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NLIFCLDM_00746 7.6e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLIFCLDM_00747 6.4e-57 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NLIFCLDM_00748 3.1e-59 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NLIFCLDM_00749 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLIFCLDM_00750 1.6e-59
NLIFCLDM_00751 2.7e-09 S Protein of unknown function (DUF805)
NLIFCLDM_00752 9.3e-10 S Protein of unknown function (DUF805)
NLIFCLDM_00753 8.9e-10 yhaI S Protein of unknown function (DUF805)
NLIFCLDM_00755 1.7e-217 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NLIFCLDM_00756 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NLIFCLDM_00757 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
NLIFCLDM_00758 1.3e-178 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NLIFCLDM_00759 2.6e-100 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NLIFCLDM_00760 8.2e-72
NLIFCLDM_00762 1.2e-26 S Cysteine-rich CPCC
NLIFCLDM_00764 4.3e-09 M LysM domain
NLIFCLDM_00765 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NLIFCLDM_00766 1e-27 ysxB J Cysteine protease Prp
NLIFCLDM_00767 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
NLIFCLDM_00770 2.2e-08 S Protein of unknown function (DUF2922)
NLIFCLDM_00772 9.8e-17 K DNA-templated transcription, initiation
NLIFCLDM_00774 1.2e-65 H Methyltransferase domain
NLIFCLDM_00775 6e-46 cps2D 5.1.3.2 M RmlD substrate binding domain
NLIFCLDM_00776 3.3e-41 wecD M Acetyltransferase (GNAT) family
NLIFCLDM_00778 3.1e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
NLIFCLDM_00779 4.4e-41 S Protein of unknown function (DUF1211)
NLIFCLDM_00781 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
NLIFCLDM_00782 9.2e-31 S CHY zinc finger
NLIFCLDM_00783 3.6e-39 K Transcriptional regulator
NLIFCLDM_00784 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
NLIFCLDM_00785 6.3e-09
NLIFCLDM_00787 1.8e-124 M Glycosyl transferases group 1
NLIFCLDM_00788 2.9e-63 M Glycosyl transferases group 1
NLIFCLDM_00789 3.7e-179 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NLIFCLDM_00790 1.5e-144 lspL 5.1.3.6 GM RmlD substrate binding domain
NLIFCLDM_00791 5.3e-103 cps2I S Psort location CytoplasmicMembrane, score
NLIFCLDM_00792 1.3e-35 cps1B GT2,GT4 M Glycosyl transferases group 1
NLIFCLDM_00793 8.4e-10 cps1B GT2,GT4 M Glycosyl transferases group 1
NLIFCLDM_00794 6.1e-117 S Glycosyltransferase WbsX
NLIFCLDM_00795 7e-53
NLIFCLDM_00796 5.1e-07 S EpsG family
NLIFCLDM_00797 1.8e-55 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
NLIFCLDM_00798 1.7e-42 GT2 S Glycosyltransferase, group 2 family protein
NLIFCLDM_00799 3.2e-73 M Glycosyltransferase Family 4
NLIFCLDM_00800 6e-75 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
NLIFCLDM_00801 4.7e-80 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
NLIFCLDM_00802 1.5e-26 2.4.1.52 GT4 M Glycosyl transferase 4-like
NLIFCLDM_00803 6.5e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
NLIFCLDM_00804 4e-76 epsL M Bacterial sugar transferase
NLIFCLDM_00805 3.3e-109 2.6.1.102 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NLIFCLDM_00806 6.3e-48 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
NLIFCLDM_00807 4.8e-86 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM CoA-binding domain
NLIFCLDM_00808 4.8e-119 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NLIFCLDM_00809 7.2e-65 cpsD D AAA domain
NLIFCLDM_00810 5.3e-48 cps4C M Chain length determinant protein
NLIFCLDM_00811 1.8e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NLIFCLDM_00812 4.5e-178 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NLIFCLDM_00813 8.1e-81
NLIFCLDM_00814 5.8e-82 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NLIFCLDM_00815 2.3e-113 yitU 3.1.3.104 S hydrolase
NLIFCLDM_00816 1.2e-59 speG J Acetyltransferase (GNAT) domain
NLIFCLDM_00817 7.4e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NLIFCLDM_00818 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NLIFCLDM_00819 2e-205 pipD E Dipeptidase
NLIFCLDM_00820 1.5e-44
NLIFCLDM_00821 2.6e-64 K helix_turn_helix, arabinose operon control protein
NLIFCLDM_00822 2e-53 S Membrane
NLIFCLDM_00823 1.3e-187 rafA 3.2.1.22 G alpha-galactosidase
NLIFCLDM_00824 1.1e-127 rafA 3.2.1.22 G alpha-galactosidase
NLIFCLDM_00825 1.5e-58 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
NLIFCLDM_00826 3.3e-191 L Helicase C-terminal domain protein
NLIFCLDM_00827 2.6e-30 L Helicase C-terminal domain protein
NLIFCLDM_00828 1.1e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
NLIFCLDM_00829 9e-96 tnp2 L Transposase
NLIFCLDM_00830 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NLIFCLDM_00831 3.5e-112 2.7.7.65 T diguanylate cyclase activity
NLIFCLDM_00832 0.0 ydaN S Bacterial cellulose synthase subunit
NLIFCLDM_00833 6.9e-202 ydaM M Glycosyl transferase family group 2
NLIFCLDM_00834 5.5e-204 S Protein conserved in bacteria
NLIFCLDM_00835 1.4e-182
NLIFCLDM_00836 2.5e-128 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
NLIFCLDM_00837 1.1e-42 2.7.7.65 T GGDEF domain
NLIFCLDM_00838 1.1e-144 pbuO_1 S Permease family
NLIFCLDM_00839 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
NLIFCLDM_00840 2.8e-104 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NLIFCLDM_00841 4e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NLIFCLDM_00842 5.7e-218 cydD CO ABC transporter transmembrane region
NLIFCLDM_00843 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NLIFCLDM_00844 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NLIFCLDM_00845 2.1e-194 cydA 1.10.3.14 C ubiquinol oxidase
NLIFCLDM_00846 3.8e-158 asnA 6.3.1.1 F aspartate--ammonia ligase
NLIFCLDM_00847 6.3e-28 xlyB 3.5.1.28 CBM50 M LysM domain
NLIFCLDM_00848 5e-19 glpE P Rhodanese Homology Domain
NLIFCLDM_00849 4.2e-49 lytE M LysM domain protein
NLIFCLDM_00850 1.5e-91 T Calcineurin-like phosphoesterase superfamily domain
NLIFCLDM_00851 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
NLIFCLDM_00853 4.4e-74 draG O ADP-ribosylglycohydrolase
NLIFCLDM_00854 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NLIFCLDM_00855 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NLIFCLDM_00856 8.6e-62 divIVA D DivIVA domain protein
NLIFCLDM_00857 5.9e-82 ylmH S S4 domain protein
NLIFCLDM_00858 3e-19 yggT S YGGT family
NLIFCLDM_00859 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NLIFCLDM_00860 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NLIFCLDM_00861 1.2e-189 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NLIFCLDM_00862 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NLIFCLDM_00863 2.3e-153 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLIFCLDM_00864 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NLIFCLDM_00865 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLIFCLDM_00866 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
NLIFCLDM_00867 2.5e-11 ftsL D cell division protein FtsL
NLIFCLDM_00868 1.8e-141 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NLIFCLDM_00869 1.5e-55 mraZ K Belongs to the MraZ family
NLIFCLDM_00870 3.4e-08 S Protein of unknown function (DUF3397)
NLIFCLDM_00871 2.3e-154 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
NLIFCLDM_00873 2.2e-99 D Alpha beta
NLIFCLDM_00874 9.7e-110 aatB ET ABC transporter substrate-binding protein
NLIFCLDM_00875 6.9e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NLIFCLDM_00876 1.9e-94 glnP P ABC transporter permease
NLIFCLDM_00877 1.8e-126 minD D Belongs to the ParA family
NLIFCLDM_00878 1.9e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NLIFCLDM_00879 1.5e-54 mreD M rod shape-determining protein MreD
NLIFCLDM_00880 2.1e-88 mreC M Involved in formation and maintenance of cell shape
NLIFCLDM_00881 1e-155 mreB D cell shape determining protein MreB
NLIFCLDM_00882 4.5e-21 K Cold shock
NLIFCLDM_00883 6.2e-80 radC L DNA repair protein
NLIFCLDM_00884 2.8e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NLIFCLDM_00885 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NLIFCLDM_00886 3.2e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLIFCLDM_00887 3.8e-162 iscS2 2.8.1.7 E Aminotransferase class V
NLIFCLDM_00888 2.4e-173 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NLIFCLDM_00889 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
NLIFCLDM_00890 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NLIFCLDM_00891 1e-23 yueI S Protein of unknown function (DUF1694)
NLIFCLDM_00892 4.9e-187 rarA L recombination factor protein RarA
NLIFCLDM_00894 3.2e-73 usp6 T universal stress protein
NLIFCLDM_00895 3.7e-54 tag 3.2.2.20 L glycosylase
NLIFCLDM_00896 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NLIFCLDM_00897 8.5e-124 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NLIFCLDM_00899 1.5e-75 yviA S Protein of unknown function (DUF421)
NLIFCLDM_00900 4e-27 S Protein of unknown function (DUF3290)
NLIFCLDM_00901 2e-278 pbp2b 3.4.16.4 M Penicillin-binding Protein
NLIFCLDM_00902 7.8e-296 S membrane
NLIFCLDM_00903 9.6e-81 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NLIFCLDM_00904 3.1e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
NLIFCLDM_00905 2.2e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
NLIFCLDM_00906 1.2e-140 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NLIFCLDM_00908 1.4e-16
NLIFCLDM_00909 2.5e-200 oatA I Acyltransferase
NLIFCLDM_00910 4.8e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NLIFCLDM_00911 4.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NLIFCLDM_00912 1.3e-139 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLIFCLDM_00915 1.5e-41 S Phosphoesterase
NLIFCLDM_00916 2.2e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NLIFCLDM_00917 1.1e-60 yslB S Protein of unknown function (DUF2507)
NLIFCLDM_00918 9.9e-41 trxA O Belongs to the thioredoxin family
NLIFCLDM_00919 1.6e-308 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NLIFCLDM_00920 1.6e-17 cvpA S Colicin V production protein
NLIFCLDM_00921 6.4e-16 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NLIFCLDM_00922 2.5e-33 yrzB S Belongs to the UPF0473 family
NLIFCLDM_00923 2.3e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NLIFCLDM_00924 2.1e-36 yrzL S Belongs to the UPF0297 family
NLIFCLDM_00925 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLIFCLDM_00926 4.3e-186 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NLIFCLDM_00927 1.6e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NLIFCLDM_00928 7.5e-13
NLIFCLDM_00929 1.6e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLIFCLDM_00930 7.4e-248 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NLIFCLDM_00931 4.7e-17 yneR
NLIFCLDM_00932 4.3e-230 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NLIFCLDM_00933 1.9e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
NLIFCLDM_00934 2.4e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NLIFCLDM_00935 7.6e-153 mdtG EGP Major facilitator Superfamily
NLIFCLDM_00936 1.7e-14 yobS K transcriptional regulator
NLIFCLDM_00937 3.7e-109 glcU U sugar transport
NLIFCLDM_00938 3.4e-170 yjjP S Putative threonine/serine exporter
NLIFCLDM_00939 1.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
NLIFCLDM_00940 3.7e-96 yicL EG EamA-like transporter family
NLIFCLDM_00941 2.3e-199 pepF E Oligopeptidase F
NLIFCLDM_00942 2.6e-07 pepF E Oligopeptidase F
NLIFCLDM_00943 3e-109 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NLIFCLDM_00944 9.8e-179 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NLIFCLDM_00945 1.9e-139 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
NLIFCLDM_00946 3.8e-62 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NLIFCLDM_00947 2.8e-24 relB L RelB antitoxin
NLIFCLDM_00949 1.3e-172 S Putative peptidoglycan binding domain
NLIFCLDM_00950 7.1e-32 K Transcriptional regulator, MarR family
NLIFCLDM_00951 1.4e-202 XK27_09600 V ABC transporter, ATP-binding protein
NLIFCLDM_00952 4.1e-229 V ABC transporter transmembrane region
NLIFCLDM_00953 2.1e-106 yxeH S hydrolase
NLIFCLDM_00954 9e-114 K response regulator
NLIFCLDM_00955 4.3e-272 vicK 2.7.13.3 T Histidine kinase
NLIFCLDM_00956 4.6e-103 yycH S YycH protein
NLIFCLDM_00957 5.6e-80 yycI S YycH protein
NLIFCLDM_00958 6.8e-30 yyaQ S YjbR
NLIFCLDM_00959 1.3e-116 vicX 3.1.26.11 S domain protein
NLIFCLDM_00960 6.9e-144 htrA 3.4.21.107 O serine protease
NLIFCLDM_00961 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NLIFCLDM_00962 4.4e-40 1.6.5.2 GM NAD(P)H-binding
NLIFCLDM_00963 7.4e-25 K MarR family transcriptional regulator
NLIFCLDM_00964 3.5e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
NLIFCLDM_00965 1.5e-28 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NLIFCLDM_00966 6.1e-07 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NLIFCLDM_00968 6.2e-204 G glycerol-3-phosphate transporter
NLIFCLDM_00969 5.5e-20 L Helix-turn-helix domain
NLIFCLDM_00970 6.2e-69 L HTH-like domain
NLIFCLDM_00971 3.2e-66 yrjD S LUD domain
NLIFCLDM_00972 1.1e-244 lutB C 4Fe-4S dicluster domain
NLIFCLDM_00973 7.6e-116 lutA C Cysteine-rich domain
NLIFCLDM_00974 2e-208 yfnA E Amino Acid
NLIFCLDM_00976 4.3e-61 uspA T universal stress protein
NLIFCLDM_00978 1.8e-12 yajC U Preprotein translocase
NLIFCLDM_00979 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NLIFCLDM_00980 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NLIFCLDM_00981 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NLIFCLDM_00982 7.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NLIFCLDM_00983 6e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NLIFCLDM_00984 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NLIFCLDM_00985 1.3e-181 rny S Endoribonuclease that initiates mRNA decay
NLIFCLDM_00986 6.7e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NLIFCLDM_00987 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLIFCLDM_00988 1.5e-63 ymfM S Helix-turn-helix domain
NLIFCLDM_00989 1.9e-90 IQ Enoyl-(Acyl carrier protein) reductase
NLIFCLDM_00990 7.8e-148 ymfH S Peptidase M16
NLIFCLDM_00991 1.8e-109 ymfF S Peptidase M16 inactive domain protein
NLIFCLDM_00992 7e-285 ftsK D Belongs to the FtsK SpoIIIE SftA family
NLIFCLDM_00993 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NLIFCLDM_00994 7.5e-99 rrmA 2.1.1.187 H Methyltransferase
NLIFCLDM_00995 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
NLIFCLDM_00996 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NLIFCLDM_00997 1.3e-198 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NLIFCLDM_00998 5.4e-21 cutC P Participates in the control of copper homeostasis
NLIFCLDM_00999 1.1e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NLIFCLDM_01000 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NLIFCLDM_01001 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLIFCLDM_01002 3.1e-68 ybbR S YbbR-like protein
NLIFCLDM_01003 2.9e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NLIFCLDM_01004 2.4e-71 S Protein of unknown function (DUF1361)
NLIFCLDM_01005 4.6e-115 murB 1.3.1.98 M Cell wall formation
NLIFCLDM_01006 1.5e-68 dnaQ 2.7.7.7 L DNA polymerase III
NLIFCLDM_01007 2.5e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NLIFCLDM_01008 5.7e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NLIFCLDM_01009 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NLIFCLDM_01010 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
NLIFCLDM_01011 4.1e-42 yxjI
NLIFCLDM_01012 2e-69 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NLIFCLDM_01013 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NLIFCLDM_01014 2.8e-19 secG U Preprotein translocase
NLIFCLDM_01015 7e-180 clcA P chloride
NLIFCLDM_01016 8.7e-146 lmrP E Major Facilitator Superfamily
NLIFCLDM_01017 1.4e-169 T PhoQ Sensor
NLIFCLDM_01018 1.1e-103 K response regulator
NLIFCLDM_01019 1.1e-131 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NLIFCLDM_01020 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NLIFCLDM_01021 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NLIFCLDM_01022 6.2e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NLIFCLDM_01023 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NLIFCLDM_01024 8.4e-137 cggR K Putative sugar-binding domain
NLIFCLDM_01026 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NLIFCLDM_01027 1.8e-149 whiA K May be required for sporulation
NLIFCLDM_01028 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NLIFCLDM_01029 7.5e-126 rapZ S Displays ATPase and GTPase activities
NLIFCLDM_01030 5.9e-80 ylbE GM NAD dependent epimerase dehydratase family protein
NLIFCLDM_01031 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NLIFCLDM_01032 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NLIFCLDM_01033 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NLIFCLDM_01034 1e-272 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NLIFCLDM_01035 4.3e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NLIFCLDM_01036 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NLIFCLDM_01037 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NLIFCLDM_01038 3.2e-08 KT PspC domain protein
NLIFCLDM_01039 4.5e-85 phoR 2.7.13.3 T Histidine kinase
NLIFCLDM_01040 1.7e-85 K response regulator
NLIFCLDM_01041 5.3e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
NLIFCLDM_01042 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NLIFCLDM_01043 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLIFCLDM_01044 9.1e-95 yeaN P Major Facilitator Superfamily
NLIFCLDM_01045 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NLIFCLDM_01046 1e-45 comFC S Competence protein
NLIFCLDM_01047 1.6e-127 comFA L Helicase C-terminal domain protein
NLIFCLDM_01048 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
NLIFCLDM_01049 1.2e-295 ydaO E amino acid
NLIFCLDM_01050 4.3e-269 aha1 P COG COG0474 Cation transport ATPase
NLIFCLDM_01051 4.8e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NLIFCLDM_01052 1.6e-32 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NLIFCLDM_01053 2.4e-33 S CAAX protease self-immunity
NLIFCLDM_01054 3.7e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NLIFCLDM_01055 4.6e-253 uup S ABC transporter, ATP-binding protein
NLIFCLDM_01056 8.4e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NLIFCLDM_01057 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NLIFCLDM_01058 3.1e-69 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NLIFCLDM_01059 1.6e-140 ansA 3.5.1.1 EJ Asparaginase
NLIFCLDM_01060 1.9e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
NLIFCLDM_01061 7.1e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NLIFCLDM_01062 1.4e-40 yabA L Involved in initiation control of chromosome replication
NLIFCLDM_01063 2.3e-83 holB 2.7.7.7 L DNA polymerase III
NLIFCLDM_01064 1.1e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NLIFCLDM_01065 7.1e-29 yaaL S Protein of unknown function (DUF2508)
NLIFCLDM_01066 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NLIFCLDM_01067 1.4e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NLIFCLDM_01068 7.9e-212 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLIFCLDM_01069 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NLIFCLDM_01070 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
NLIFCLDM_01071 2.7e-27 nrdH O Glutaredoxin
NLIFCLDM_01072 4.8e-45 nrdI F NrdI Flavodoxin like
NLIFCLDM_01073 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLIFCLDM_01074 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLIFCLDM_01075 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLIFCLDM_01076 1.4e-54
NLIFCLDM_01077 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NLIFCLDM_01078 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NLIFCLDM_01079 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NLIFCLDM_01080 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NLIFCLDM_01081 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
NLIFCLDM_01082 3.4e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NLIFCLDM_01083 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NLIFCLDM_01084 7e-71 yacP S YacP-like NYN domain
NLIFCLDM_01085 3.2e-109 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLIFCLDM_01086 9.3e-55 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NLIFCLDM_01087 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLIFCLDM_01088 7.1e-246 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLIFCLDM_01089 8.2e-154 yacL S domain protein
NLIFCLDM_01090 1.6e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NLIFCLDM_01091 4e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NLIFCLDM_01092 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
NLIFCLDM_01093 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
NLIFCLDM_01094 1e-33 S Enterocin A Immunity
NLIFCLDM_01095 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLIFCLDM_01096 4.5e-129 mleP2 S Sodium Bile acid symporter family
NLIFCLDM_01097 9.5e-114 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLIFCLDM_01099 1.1e-42 ydcK S Belongs to the SprT family
NLIFCLDM_01100 4.4e-252 yhgF K Tex-like protein N-terminal domain protein
NLIFCLDM_01101 2.3e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NLIFCLDM_01102 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NLIFCLDM_01103 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NLIFCLDM_01104 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
NLIFCLDM_01105 3e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLIFCLDM_01107 1.1e-07
NLIFCLDM_01108 1.6e-197 dtpT U amino acid peptide transporter
NLIFCLDM_01109 3.8e-93 yihY S Belongs to the UPF0761 family
NLIFCLDM_01110 4.7e-12 mltD CBM50 M Lysin motif
NLIFCLDM_01111 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NLIFCLDM_01112 1.3e-142 map 3.4.11.18 E Methionine Aminopeptidase
NLIFCLDM_01113 8.8e-54 fld C Flavodoxin
NLIFCLDM_01114 8.7e-53 gtcA S Teichoic acid glycosylation protein
NLIFCLDM_01115 0.0 S Bacterial membrane protein YfhO
NLIFCLDM_01116 3.1e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
NLIFCLDM_01117 1.7e-122 S Sulfite exporter TauE/SafE
NLIFCLDM_01118 1.1e-70 K Sugar-specific transcriptional regulator TrmB
NLIFCLDM_01119 7.1e-169 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NLIFCLDM_01120 1.3e-181 pepS E Thermophilic metalloprotease (M29)
NLIFCLDM_01121 6.7e-266 E Amino acid permease
NLIFCLDM_01122 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NLIFCLDM_01123 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NLIFCLDM_01124 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
NLIFCLDM_01125 4.3e-213 malT G Transporter, major facilitator family protein
NLIFCLDM_01126 9.4e-101 malR K Transcriptional regulator, LacI family
NLIFCLDM_01127 3.9e-279 kup P Transport of potassium into the cell
NLIFCLDM_01129 1.5e-20 S Domain of unknown function (DUF3284)
NLIFCLDM_01130 4.7e-161 yfmL L DEAD DEAH box helicase
NLIFCLDM_01131 5.4e-128 mocA S Oxidoreductase
NLIFCLDM_01132 2e-24 S Domain of unknown function (DUF4828)
NLIFCLDM_01133 6.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
NLIFCLDM_01134 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NLIFCLDM_01135 1.8e-193 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
NLIFCLDM_01136 1.2e-118 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
NLIFCLDM_01137 1.4e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NLIFCLDM_01138 1.1e-265 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NLIFCLDM_01139 6.1e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NLIFCLDM_01140 4.9e-42 O ADP-ribosylglycohydrolase
NLIFCLDM_01141 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NLIFCLDM_01142 4.9e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NLIFCLDM_01143 1.3e-34 K GNAT family
NLIFCLDM_01144 1.7e-40
NLIFCLDM_01146 1.6e-159 mgtE P Acts as a magnesium transporter
NLIFCLDM_01147 9.7e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NLIFCLDM_01148 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLIFCLDM_01149 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
NLIFCLDM_01150 4.2e-41 topB 5.99.1.2 L DNA topoisomerase
NLIFCLDM_01151 5.5e-212 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NLIFCLDM_01152 1.4e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NLIFCLDM_01153 1.3e-193 pbuX F xanthine permease
NLIFCLDM_01154 1.4e-72 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NLIFCLDM_01155 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
NLIFCLDM_01156 3.2e-64 S ECF transporter, substrate-specific component
NLIFCLDM_01157 1.7e-126 mleP S Sodium Bile acid symporter family
NLIFCLDM_01158 4.9e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NLIFCLDM_01159 6.2e-72 mleR K LysR family
NLIFCLDM_01160 1.4e-56 K transcriptional
NLIFCLDM_01161 2.6e-41 K Bacterial regulatory proteins, tetR family
NLIFCLDM_01162 6.8e-59 T Belongs to the universal stress protein A family
NLIFCLDM_01163 1.2e-44 K Copper transport repressor CopY TcrY
NLIFCLDM_01164 6.3e-227 3.2.1.18 GH33 M Rib/alpha-like repeat
NLIFCLDM_01166 1.9e-95 ypuA S Protein of unknown function (DUF1002)
NLIFCLDM_01167 2.9e-48 dedA 3.1.3.1 S SNARE associated Golgi protein
NLIFCLDM_01168 8.8e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLIFCLDM_01169 9.2e-18 yncA 2.3.1.79 S Maltose acetyltransferase
NLIFCLDM_01170 3.1e-206 yflS P Sodium:sulfate symporter transmembrane region
NLIFCLDM_01171 4.7e-199 frdC 1.3.5.4 C FAD binding domain
NLIFCLDM_01172 1.9e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NLIFCLDM_01173 5.7e-14 ybaN S Protein of unknown function (DUF454)
NLIFCLDM_01174 2.2e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NLIFCLDM_01175 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NLIFCLDM_01176 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLIFCLDM_01177 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NLIFCLDM_01178 1.9e-71 ywlG S Belongs to the UPF0340 family
NLIFCLDM_01179 3.1e-150 C Oxidoreductase
NLIFCLDM_01180 5.9e-177 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
NLIFCLDM_01181 4.3e-69 S Domain of unknown function (DUF3841)
NLIFCLDM_01182 1.6e-56 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
NLIFCLDM_01183 1e-104 S Domain of unknown function (DUF4343)
NLIFCLDM_01184 0.0 L helicase activity
NLIFCLDM_01185 7.6e-212 K DNA binding
NLIFCLDM_01186 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
NLIFCLDM_01187 3.4e-224 mod 2.1.1.72, 3.1.21.5 L DNA methylase
NLIFCLDM_01188 1.1e-163 mcrC V Psort location Cytoplasmic, score
NLIFCLDM_01189 0.0 mcrB 2.1.1.72 V ATPase family associated with various cellular activities (AAA)
NLIFCLDM_01190 3.4e-16
NLIFCLDM_01191 1.5e-210 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLIFCLDM_01192 2.2e-145 yegS 2.7.1.107 G Lipid kinase
NLIFCLDM_01193 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLIFCLDM_01194 2e-232 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NLIFCLDM_01195 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLIFCLDM_01196 9.3e-161 camS S sex pheromone
NLIFCLDM_01197 3.9e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLIFCLDM_01198 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NLIFCLDM_01199 1e-143 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NLIFCLDM_01202 1.1e-259 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NLIFCLDM_01203 4.7e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLIFCLDM_01204 4.1e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NLIFCLDM_01205 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NLIFCLDM_01206 7.4e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NLIFCLDM_01207 4.2e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NLIFCLDM_01208 1.1e-40 yabR J RNA binding
NLIFCLDM_01209 1e-21 divIC D Septum formation initiator
NLIFCLDM_01210 6.2e-31 yabO J S4 domain protein
NLIFCLDM_01211 5.1e-141 yabM S Polysaccharide biosynthesis protein
NLIFCLDM_01212 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NLIFCLDM_01213 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NLIFCLDM_01214 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NLIFCLDM_01215 6.6e-25 V Restriction endonuclease
NLIFCLDM_01216 1.5e-83 S (CBS) domain
NLIFCLDM_01217 8.1e-142 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLIFCLDM_01218 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NLIFCLDM_01219 7.2e-53 perR P Belongs to the Fur family
NLIFCLDM_01220 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
NLIFCLDM_01221 2.7e-98 sbcC L Putative exonuclease SbcCD, C subunit
NLIFCLDM_01222 1.8e-113 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NLIFCLDM_01223 2.1e-36 M LysM domain protein
NLIFCLDM_01224 3e-278 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NLIFCLDM_01225 1.4e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NLIFCLDM_01226 1.2e-35 ygfC K Bacterial regulatory proteins, tetR family
NLIFCLDM_01227 1e-100 hrtB V ABC transporter permease
NLIFCLDM_01228 3.4e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NLIFCLDM_01229 4e-67 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NLIFCLDM_01230 0.0 helD 3.6.4.12 L DNA helicase
NLIFCLDM_01231 4e-246 yjbQ P TrkA C-terminal domain protein
NLIFCLDM_01232 4.2e-29
NLIFCLDM_01233 2.1e-21 L COG3547 Transposase and inactivated derivatives
NLIFCLDM_01234 1.9e-216 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NLIFCLDM_01235 1.2e-148 mepA V MATE efflux family protein
NLIFCLDM_01236 5.1e-34 lsa S ABC transporter
NLIFCLDM_01237 6e-107 lsa S ABC transporter
NLIFCLDM_01238 4.8e-14
NLIFCLDM_01239 4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLIFCLDM_01240 1e-109 puuD S peptidase C26
NLIFCLDM_01241 9.8e-202 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NLIFCLDM_01242 1.1e-25
NLIFCLDM_01243 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
NLIFCLDM_01244 1.7e-60 uspA T Universal stress protein family
NLIFCLDM_01246 1.8e-209 glnP P ABC transporter
NLIFCLDM_01247 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NLIFCLDM_01248 2.8e-118 V ABC-2 family transporter protein
NLIFCLDM_01249 2.9e-115 V ABC-2 family transporter protein
NLIFCLDM_01250 1.3e-162 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
NLIFCLDM_01251 7.9e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NLIFCLDM_01252 6.5e-219 T PhoQ Sensor
NLIFCLDM_01253 2.9e-75 O Ergosterol biosynthesis ERG4/ERG24 family
NLIFCLDM_01254 8.2e-58 doc S Fic/DOC family
NLIFCLDM_01255 1.5e-34 S Antitoxin component of a toxin-antitoxin (TA) module
NLIFCLDM_01256 2.6e-107 L ATPase involved in DNA repair
NLIFCLDM_01257 8.9e-180 L ATPase involved in DNA repair
NLIFCLDM_01258 6.1e-66
NLIFCLDM_01259 1e-79 T Nacht domain
NLIFCLDM_01260 8.8e-72 T Nacht domain
NLIFCLDM_01261 1.2e-21
NLIFCLDM_01262 3.8e-91 L Integrase
NLIFCLDM_01263 1.8e-145 IQ KR domain
NLIFCLDM_01264 6e-92 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NLIFCLDM_01266 4.1e-81 tatD L TatD related DNase
NLIFCLDM_01267 4.8e-27 tatD L TatD related DNase
NLIFCLDM_01269 1.1e-34 adhB 1.1.1.1, 1.1.1.14 C alcohol dehydrogenase
NLIFCLDM_01270 4.3e-219 cna M This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NLIFCLDM_01271 3.4e-185 M domain protein
NLIFCLDM_01272 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
NLIFCLDM_01273 2.1e-76 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NLIFCLDM_01274 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NLIFCLDM_01275 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLIFCLDM_01276 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLIFCLDM_01277 4e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLIFCLDM_01278 1.4e-52 rplQ J Ribosomal protein L17
NLIFCLDM_01279 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLIFCLDM_01280 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NLIFCLDM_01281 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NLIFCLDM_01282 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NLIFCLDM_01283 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NLIFCLDM_01284 1.7e-106 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NLIFCLDM_01285 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NLIFCLDM_01286 1e-67 rplO J Binds to the 23S rRNA
NLIFCLDM_01287 2.1e-22 rpmD J Ribosomal protein L30
NLIFCLDM_01288 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NLIFCLDM_01289 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NLIFCLDM_01290 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NLIFCLDM_01291 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NLIFCLDM_01292 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLIFCLDM_01293 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NLIFCLDM_01294 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NLIFCLDM_01295 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NLIFCLDM_01296 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NLIFCLDM_01297 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
NLIFCLDM_01298 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NLIFCLDM_01299 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NLIFCLDM_01300 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NLIFCLDM_01301 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NLIFCLDM_01302 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NLIFCLDM_01303 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NLIFCLDM_01304 1e-100 rplD J Forms part of the polypeptide exit tunnel
NLIFCLDM_01305 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NLIFCLDM_01306 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NLIFCLDM_01307 4.3e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NLIFCLDM_01308 6.5e-79 K rpiR family
NLIFCLDM_01309 2.6e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NLIFCLDM_01310 2.7e-145 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
NLIFCLDM_01311 6.5e-21 K Acetyltransferase (GNAT) domain
NLIFCLDM_01312 3.8e-182 steT E amino acid
NLIFCLDM_01313 9.6e-78 glnP P ABC transporter permease
NLIFCLDM_01314 1.2e-85 gluC P ABC transporter permease
NLIFCLDM_01315 1.9e-99 glnH ET ABC transporter
NLIFCLDM_01316 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NLIFCLDM_01317 1.9e-13
NLIFCLDM_01318 1.4e-97
NLIFCLDM_01319 3e-12 3.2.1.14 GH18
NLIFCLDM_01320 5.4e-53 zur P Belongs to the Fur family
NLIFCLDM_01321 6.3e-212 yfnA E Amino Acid
NLIFCLDM_01322 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NLIFCLDM_01323 0.0 L Helicase C-terminal domain protein
NLIFCLDM_01324 1.7e-78 ptp2 3.1.3.48 T Tyrosine phosphatase family
NLIFCLDM_01325 9.3e-181 yhdP S Transporter associated domain
NLIFCLDM_01326 3.7e-26
NLIFCLDM_01327 1.2e-14 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLIFCLDM_01328 2.6e-51 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLIFCLDM_01329 1.6e-131 bacI V MacB-like periplasmic core domain
NLIFCLDM_01330 3.3e-97 V ABC transporter
NLIFCLDM_01331 2e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLIFCLDM_01332 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
NLIFCLDM_01333 8.1e-140 V MatE
NLIFCLDM_01334 1.2e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLIFCLDM_01335 5e-87 S Alpha beta hydrolase
NLIFCLDM_01336 4.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NLIFCLDM_01337 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NLIFCLDM_01338 1.3e-111 argE 3.5.1.18 E Peptidase dimerisation domain
NLIFCLDM_01339 1.6e-100 IQ Enoyl-(Acyl carrier protein) reductase
NLIFCLDM_01340 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
NLIFCLDM_01341 4.3e-54 queT S QueT transporter
NLIFCLDM_01343 1.5e-65 degV S Uncharacterised protein, DegV family COG1307
NLIFCLDM_01344 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLIFCLDM_01345 2.7e-21 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLIFCLDM_01346 1.9e-34 trxA O Belongs to the thioredoxin family
NLIFCLDM_01347 1.2e-85 S Sucrose-6F-phosphate phosphohydrolase
NLIFCLDM_01348 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NLIFCLDM_01349 4.9e-49 S Threonine/Serine exporter, ThrE
NLIFCLDM_01350 4.3e-82 thrE S Putative threonine/serine exporter
NLIFCLDM_01351 3.1e-27 cspC K Cold shock protein
NLIFCLDM_01352 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
NLIFCLDM_01353 3.1e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NLIFCLDM_01354 3.1e-23
NLIFCLDM_01355 2.1e-58 3.6.1.27 I phosphatase
NLIFCLDM_01356 3.1e-25
NLIFCLDM_01357 1.5e-51 I alpha/beta hydrolase fold
NLIFCLDM_01359 1.3e-38 azlD S branched-chain amino acid
NLIFCLDM_01360 1.9e-104 azlC E AzlC protein
NLIFCLDM_01361 3.5e-17
NLIFCLDM_01362 4.9e-119 xth 3.1.11.2 L exodeoxyribonuclease III
NLIFCLDM_01363 5.4e-91 V domain protein
NLIFCLDM_01369 8.1e-09 S zinc-ribbon domain
NLIFCLDM_01371 4e-11 S Mor transcription activator family
NLIFCLDM_01372 2.3e-59 yfjR K WYL domain
NLIFCLDM_01373 6e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLIFCLDM_01374 1.9e-172 malY 4.4.1.8 E Aminotransferase, class I
NLIFCLDM_01375 4e-118 K AI-2E family transporter
NLIFCLDM_01376 4.4e-60 EG EamA-like transporter family
NLIFCLDM_01377 8.8e-76 L haloacid dehalogenase-like hydrolase
NLIFCLDM_01378 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NLIFCLDM_01379 5e-67 1.5.1.38 S NADPH-dependent FMN reductase
NLIFCLDM_01380 3.7e-164 C Luciferase-like monooxygenase
NLIFCLDM_01381 1.3e-41 K Transcriptional regulator, HxlR family
NLIFCLDM_01382 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NLIFCLDM_01383 3.4e-103 ydhQ K UbiC transcription regulator-associated domain protein
NLIFCLDM_01384 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NLIFCLDM_01385 7e-82 pncA Q isochorismatase
NLIFCLDM_01386 5.1e-62 3.1.3.73 G phosphoglycerate mutase
NLIFCLDM_01387 9.5e-259 treB G phosphotransferase system
NLIFCLDM_01388 5.7e-84 treR K UTRA
NLIFCLDM_01389 2.2e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NLIFCLDM_01390 1.4e-167 mdtG EGP Major facilitator Superfamily
NLIFCLDM_01392 1.4e-195 XK27_08315 M Sulfatase
NLIFCLDM_01393 5.9e-56 S peptidoglycan catabolic process
NLIFCLDM_01394 2e-150 M BCCT, betaine/carnitine/choline family transporter
NLIFCLDM_01395 1.9e-84 M Nucleotidyl transferase
NLIFCLDM_01396 2.2e-177 licA 2.7.1.89 M Choline/ethanolamine kinase
NLIFCLDM_01397 1.2e-88 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NLIFCLDM_01398 1.2e-167 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NLIFCLDM_01399 2e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NLIFCLDM_01400 4.1e-177 thrC 4.2.3.1 E Threonine synthase
NLIFCLDM_01401 9.1e-132 S Bacterial membrane protein YfhO
NLIFCLDM_01402 3.6e-14
NLIFCLDM_01403 1.3e-75 S Psort location CytoplasmicMembrane, score
NLIFCLDM_01404 5e-147 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NLIFCLDM_01405 7.5e-39 2.7.7.65 T phosphorelay sensor kinase activity
NLIFCLDM_01406 2.4e-157 XK27_09615 S reductase
NLIFCLDM_01407 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
NLIFCLDM_01408 5.6e-97 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLIFCLDM_01409 7.3e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NLIFCLDM_01410 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NLIFCLDM_01412 1.8e-153 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
NLIFCLDM_01413 1.2e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
NLIFCLDM_01414 7.3e-38 S Acyltransferase family
NLIFCLDM_01415 1e-43 S Peptidase_C39 like family
NLIFCLDM_01418 8.5e-64 M Glycosyltransferase like family 2
NLIFCLDM_01419 2.4e-73 M LicD family
NLIFCLDM_01420 1.1e-57 cps3F
NLIFCLDM_01421 8.3e-92 M transferase activity, transferring glycosyl groups
NLIFCLDM_01422 1.3e-76 waaB GT4 M Glycosyl transferases group 1
NLIFCLDM_01423 6.9e-92 M Core-2/I-Branching enzyme
NLIFCLDM_01424 6.2e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NLIFCLDM_01425 6.2e-64 rny D Peptidase family M23
NLIFCLDM_01427 4e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NLIFCLDM_01428 1.6e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NLIFCLDM_01429 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NLIFCLDM_01430 2.7e-144 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NLIFCLDM_01431 2e-91 rfbP M Bacterial sugar transferase
NLIFCLDM_01432 2.5e-58 cpsF M Oligosaccharide biosynthesis protein Alg14 like
NLIFCLDM_01433 8.4e-38 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NLIFCLDM_01434 3.6e-28 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NLIFCLDM_01435 6e-75 xerC L Belongs to the 'phage' integrase family
NLIFCLDM_01436 3.8e-22
NLIFCLDM_01437 5.7e-80 K SIR2-like domain
NLIFCLDM_01438 8e-112 K IrrE N-terminal-like domain
NLIFCLDM_01439 4.1e-18
NLIFCLDM_01440 7.2e-38 L hmm pf00665
NLIFCLDM_01441 1.8e-49 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
NLIFCLDM_01442 8.7e-51 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
NLIFCLDM_01443 3.4e-275 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NLIFCLDM_01444 3.9e-133 coaA 2.7.1.33 F Pantothenic acid kinase
NLIFCLDM_01445 1.7e-44 E GDSL-like Lipase/Acylhydrolase
NLIFCLDM_01446 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NLIFCLDM_01447 1.6e-189 glnPH2 P ABC transporter permease
NLIFCLDM_01448 9.4e-214 yjeM E Amino Acid
NLIFCLDM_01449 3.9e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
NLIFCLDM_01450 2.5e-137 tetA EGP Major facilitator Superfamily
NLIFCLDM_01451 1e-62 S Glycosyltransferase like family 2
NLIFCLDM_01452 4.5e-117 cps1D M Domain of unknown function (DUF4422)
NLIFCLDM_01453 4.3e-38 S CAAX protease self-immunity
NLIFCLDM_01454 4.5e-88 yvyE 3.4.13.9 S YigZ family
NLIFCLDM_01455 2.3e-58 S Haloacid dehalogenase-like hydrolase
NLIFCLDM_01456 4.5e-154 EGP Major facilitator Superfamily
NLIFCLDM_01458 1.5e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NLIFCLDM_01459 2.1e-27 yraB K transcriptional regulator
NLIFCLDM_01460 1.4e-88 S NADPH-dependent FMN reductase
NLIFCLDM_01461 2.2e-100 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NLIFCLDM_01462 5.5e-55 S ECF transporter, substrate-specific component
NLIFCLDM_01463 2.8e-103 znuB U ABC 3 transport family
NLIFCLDM_01464 1e-98 fhuC P ABC transporter
NLIFCLDM_01465 1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
NLIFCLDM_01466 7.6e-38
NLIFCLDM_01467 7.3e-14 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NLIFCLDM_01468 4.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
NLIFCLDM_01469 2e-189 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NLIFCLDM_01470 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
NLIFCLDM_01471 9.1e-108 spo0J K Belongs to the ParB family
NLIFCLDM_01472 6.5e-118 soj D Sporulation initiation inhibitor
NLIFCLDM_01473 9.5e-68 noc K Belongs to the ParB family
NLIFCLDM_01474 8.1e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NLIFCLDM_01475 1.2e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NLIFCLDM_01476 2.4e-109 3.1.4.46 C phosphodiesterase
NLIFCLDM_01477 0.0 pacL 3.6.3.8 P P-type ATPase
NLIFCLDM_01478 1.8e-61 yvdD 3.2.2.10 S Possible lysine decarboxylase
NLIFCLDM_01479 1.4e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NLIFCLDM_01481 5.2e-63 srtA 3.4.22.70 M sortase family
NLIFCLDM_01482 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NLIFCLDM_01483 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NLIFCLDM_01484 3.7e-34
NLIFCLDM_01485 4.5e-140 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLIFCLDM_01486 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NLIFCLDM_01487 1.7e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLIFCLDM_01488 9e-157 manA 5.3.1.8 G mannose-6-phosphate isomerase
NLIFCLDM_01489 1.1e-39 ybjQ S Belongs to the UPF0145 family
NLIFCLDM_01490 5.7e-08
NLIFCLDM_01491 1.8e-95 V ABC transporter, ATP-binding protein
NLIFCLDM_01492 1.1e-41 gntR1 K Transcriptional regulator, GntR family
NLIFCLDM_01493 1.4e-185 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
NLIFCLDM_01494 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLIFCLDM_01495 1.1e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
NLIFCLDM_01496 2.2e-107 terC P Integral membrane protein TerC family
NLIFCLDM_01497 5.5e-39 K Transcriptional regulator
NLIFCLDM_01498 7.5e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NLIFCLDM_01499 2e-100 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NLIFCLDM_01500 4.5e-102 tcyB E ABC transporter
NLIFCLDM_01501 2.3e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NLIFCLDM_01502 1.7e-208 mtlR K Mga helix-turn-helix domain
NLIFCLDM_01503 4.3e-77 yjcE P Sodium proton antiporter
NLIFCLDM_01504 2e-85 yjcE P Sodium proton antiporter
NLIFCLDM_01505 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NLIFCLDM_01506 1.4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
NLIFCLDM_01507 3.3e-69 dhaL 2.7.1.121 S Dak2
NLIFCLDM_01508 7.6e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NLIFCLDM_01509 1.9e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NLIFCLDM_01510 1.7e-61 K Bacterial regulatory proteins, tetR family
NLIFCLDM_01511 1.9e-208 brnQ U Component of the transport system for branched-chain amino acids
NLIFCLDM_01513 5.4e-110 endA F DNA RNA non-specific endonuclease
NLIFCLDM_01514 8.2e-117 sip L Belongs to the 'phage' integrase family
NLIFCLDM_01515 5.8e-09 E IrrE N-terminal-like domain
NLIFCLDM_01516 2.4e-32 K Helix-turn-helix XRE-family like proteins
NLIFCLDM_01517 1.1e-07 K Helix-turn-helix XRE-family like proteins
NLIFCLDM_01525 1.3e-44 L DNA replication protein
NLIFCLDM_01526 2.3e-76 S DNA primase
NLIFCLDM_01528 1.1e-08
NLIFCLDM_01531 4.5e-53 K Transcriptional regulator C-terminal region
NLIFCLDM_01532 2.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
NLIFCLDM_01533 2.5e-283 pepO 3.4.24.71 O Peptidase family M13
NLIFCLDM_01534 5e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
NLIFCLDM_01535 2.1e-07 yvaZ S SdpI/YhfL protein family
NLIFCLDM_01536 8.6e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NLIFCLDM_01537 6.7e-47 hmpT S ECF-type riboflavin transporter, S component
NLIFCLDM_01538 1.3e-40 wecD K Acetyltransferase GNAT Family
NLIFCLDM_01540 1.3e-37 aguA_2 3.5.3.12 E Porphyromonas-type peptidyl-arginine deiminase
NLIFCLDM_01541 1.4e-244 XK27_06780 V ABC transporter permease
NLIFCLDM_01542 1.6e-94 XK27_06785 V ABC transporter, ATP-binding protein
NLIFCLDM_01543 3.2e-34 tetR K transcriptional regulator
NLIFCLDM_01544 1.8e-12 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NLIFCLDM_01547 9.8e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLIFCLDM_01548 8.4e-119 ytbE S reductase
NLIFCLDM_01549 4.2e-43 ytcD K HxlR-like helix-turn-helix
NLIFCLDM_01550 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
NLIFCLDM_01551 1.3e-53 ybbL S ABC transporter
NLIFCLDM_01552 3.1e-162 oxlT P Major Facilitator Superfamily
NLIFCLDM_01553 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NLIFCLDM_01554 4.1e-47 S Short repeat of unknown function (DUF308)
NLIFCLDM_01555 3e-30 tetR K Transcriptional regulator C-terminal region
NLIFCLDM_01556 1.3e-150 yfeX P Peroxidase
NLIFCLDM_01557 8.6e-17 S Protein of unknown function (DUF3021)
NLIFCLDM_01558 4.5e-39 K LytTr DNA-binding domain
NLIFCLDM_01559 9e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NLIFCLDM_01560 2.4e-208 mmuP E amino acid
NLIFCLDM_01561 9.2e-16 psiE S Phosphate-starvation-inducible E
NLIFCLDM_01562 2.2e-155 oppF P Belongs to the ABC transporter superfamily
NLIFCLDM_01563 1.3e-180 oppD P Belongs to the ABC transporter superfamily
NLIFCLDM_01564 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLIFCLDM_01565 4.6e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NLIFCLDM_01566 4.7e-203 oppA E ABC transporter, substratebinding protein
NLIFCLDM_01567 2.3e-217 yifK E Amino acid permease
NLIFCLDM_01568 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLIFCLDM_01569 3.9e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
NLIFCLDM_01570 1.4e-65 pgm3 G phosphoglycerate mutase family
NLIFCLDM_01571 2.8e-250 ctpA 3.6.3.54 P P-type ATPase
NLIFCLDM_01572 3.3e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NLIFCLDM_01573 1.5e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NLIFCLDM_01574 2.8e-149 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NLIFCLDM_01575 3.1e-22 K transcriptional regulator
NLIFCLDM_01576 3.8e-77 hchA S intracellular protease amidase
NLIFCLDM_01577 2.8e-135 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NLIFCLDM_01578 1.8e-112 lacI3 K helix_turn _helix lactose operon repressor
NLIFCLDM_01579 4.2e-231 malL 3.2.1.10 GH13 G Psort location Cytoplasmic, score
NLIFCLDM_01580 7.5e-39 2.7.1.191 G PTS system fructose IIA component
NLIFCLDM_01581 3.2e-123 G PTS system mannose/fructose/sorbose family IID component
NLIFCLDM_01582 4.4e-101 G PTS system sorbose-specific iic component
NLIFCLDM_01583 2e-64 2.7.1.191 G PTS system sorbose subfamily IIB component
NLIFCLDM_01584 1.9e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NLIFCLDM_01585 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NLIFCLDM_01586 9.9e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
NLIFCLDM_01587 2.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
NLIFCLDM_01588 9e-198 1.3.5.4 C FMN_bind
NLIFCLDM_01589 1.7e-56 3.1.3.48 K Transcriptional regulator
NLIFCLDM_01590 4.6e-159 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NLIFCLDM_01591 1.2e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NLIFCLDM_01592 4.9e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NLIFCLDM_01593 1.1e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
NLIFCLDM_01594 1.3e-99 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NLIFCLDM_01595 2.5e-82 S Belongs to the UPF0246 family
NLIFCLDM_01596 7.4e-10 V CAAX protease self-immunity
NLIFCLDM_01597 1.6e-59 ykhA 3.1.2.20 I Thioesterase superfamily
NLIFCLDM_01598 1.5e-156 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NLIFCLDM_01600 9.6e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NLIFCLDM_01601 3.9e-147 scrR K helix_turn _helix lactose operon repressor
NLIFCLDM_01602 1.8e-217 scrB 3.2.1.26 GH32 G invertase
NLIFCLDM_01603 1.8e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
NLIFCLDM_01604 3.1e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NLIFCLDM_01605 9.3e-115 ntpJ P Potassium uptake protein
NLIFCLDM_01606 2.2e-58 ktrA P TrkA-N domain
NLIFCLDM_01607 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NLIFCLDM_01608 2.2e-36 2.7.8.12 GT2 V Glycosyl transferase, family 2
NLIFCLDM_01609 1.4e-19
NLIFCLDM_01610 1.8e-94 S Predicted membrane protein (DUF2207)
NLIFCLDM_01611 1.6e-54 bioY S BioY family
NLIFCLDM_01612 9.8e-184 lmrB EGP Major facilitator Superfamily
NLIFCLDM_01613 3e-108 manR K PRD domain
NLIFCLDM_01614 3.9e-14 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
NLIFCLDM_01615 2.9e-136 4.1.2.13 G Fructose-bisphosphate aldolase class-II
NLIFCLDM_01616 2.2e-47 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLIFCLDM_01617 2.4e-34 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
NLIFCLDM_01618 9.4e-139 G Phosphotransferase System
NLIFCLDM_01619 1e-80 G Domain of unknown function (DUF4432)
NLIFCLDM_01620 9.3e-98 5.3.1.15 S Pfam:DUF1498
NLIFCLDM_01621 5.8e-171 xylB 2.7.1.12, 2.7.1.17 G Xylulose kinase
NLIFCLDM_01622 1.3e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLIFCLDM_01623 7.6e-74 glcR K DeoR C terminal sensor domain
NLIFCLDM_01624 5.9e-61 yceE S haloacid dehalogenase-like hydrolase
NLIFCLDM_01625 1.9e-41 S CAAX protease self-immunity
NLIFCLDM_01626 1.6e-33 S Domain of unknown function (DUF4811)
NLIFCLDM_01627 1.6e-197 lmrB EGP Major facilitator Superfamily
NLIFCLDM_01628 4.2e-32 merR K MerR HTH family regulatory protein
NLIFCLDM_01629 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLIFCLDM_01630 2.4e-59 S Protein of unknown function (DUF554)
NLIFCLDM_01631 4.8e-121 G Bacterial extracellular solute-binding protein
NLIFCLDM_01632 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
NLIFCLDM_01633 5.1e-99 baeS T Histidine kinase
NLIFCLDM_01634 3.1e-80 rbsB G sugar-binding domain protein
NLIFCLDM_01635 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NLIFCLDM_01636 4.9e-116 manY G PTS system sorbose-specific iic component
NLIFCLDM_01637 4.7e-147 manN G PTS system mannose/fructose/sorbose family IID component
NLIFCLDM_01638 3.2e-52 manO S Domain of unknown function (DUF956)
NLIFCLDM_01639 2.7e-70 mltD CBM50 M NlpC P60 family protein
NLIFCLDM_01640 3.6e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NLIFCLDM_01641 1.6e-163 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLIFCLDM_01642 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
NLIFCLDM_01643 1.6e-48 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NLIFCLDM_01644 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NLIFCLDM_01645 3.2e-108 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLIFCLDM_01646 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NLIFCLDM_01647 1.6e-48 S CRISPR-associated protein (Cas_Csn2)
NLIFCLDM_01648 8.1e-38 K transcriptional regulator PadR family
NLIFCLDM_01649 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
NLIFCLDM_01650 1.8e-16 S Putative adhesin
NLIFCLDM_01651 2.2e-16 pspC KT PspC domain
NLIFCLDM_01653 2.3e-13 S Enterocin A Immunity
NLIFCLDM_01654 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NLIFCLDM_01655 4.8e-260 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
NLIFCLDM_01656 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NLIFCLDM_01657 4.1e-245 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NLIFCLDM_01658 1.1e-69 pnuC H Nicotinamide mononucleotide transporter
NLIFCLDM_01659 4.3e-85 Z012_06740 S Fic/DOC family
NLIFCLDM_01660 0.0 L MobA MobL family protein
NLIFCLDM_01661 3.4e-24
NLIFCLDM_01662 2.5e-114 S Fic/DOC family
NLIFCLDM_01663 3.1e-161 repA S Replication initiator protein A
NLIFCLDM_01664 2.2e-30
NLIFCLDM_01665 2.5e-136 D CobQ CobB MinD ParA nucleotide binding domain protein
NLIFCLDM_01666 7.1e-85 L COG1961 Site-specific recombinases, DNA invertase Pin homologs
NLIFCLDM_01667 5.3e-56 K helix_turn_helix multiple antibiotic resistance protein
NLIFCLDM_01668 1.3e-26 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NLIFCLDM_01670 6.2e-55 K LytTr DNA-binding domain
NLIFCLDM_01671 1.4e-51 2.7.13.3 T GHKL domain
NLIFCLDM_01676 1.1e-16
NLIFCLDM_01678 4.2e-08
NLIFCLDM_01679 2e-39 blpT
NLIFCLDM_01680 2.3e-14
NLIFCLDM_01682 2.3e-186 mtnE 2.6.1.83 E Aminotransferase
NLIFCLDM_01683 4.5e-82 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NLIFCLDM_01684 1.3e-66 S Protein of unknown function (DUF1440)
NLIFCLDM_01685 7.7e-41 S Iron-sulfur cluster assembly protein
NLIFCLDM_01686 4.7e-112 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NLIFCLDM_01687 1.1e-73 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NLIFCLDM_01688 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NLIFCLDM_01689 7.4e-153 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NLIFCLDM_01690 4e-64 G Xylose isomerase domain protein TIM barrel
NLIFCLDM_01691 5.1e-48 ndk 2.7.4.6 F Belongs to the NDK family
NLIFCLDM_01692 6.5e-90 nanK GK ROK family
NLIFCLDM_01693 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NLIFCLDM_01694 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NLIFCLDM_01695 4.3e-75 K Helix-turn-helix domain, rpiR family
NLIFCLDM_01696 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
NLIFCLDM_01697 4.5e-216 yjeM E Amino Acid
NLIFCLDM_01699 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLIFCLDM_01700 5.3e-233 tetP J elongation factor G
NLIFCLDM_01701 5.2e-276 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NLIFCLDM_01702 2.3e-87 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NLIFCLDM_01703 1.1e-166 gutB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NLIFCLDM_01704 1.2e-119 gatD 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NLIFCLDM_01705 2.4e-181 gatC G PTS system sugar-specific permease component
NLIFCLDM_01706 2e-35 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
NLIFCLDM_01707 2.1e-39 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NLIFCLDM_01708 2.2e-60 K DeoR C terminal sensor domain
NLIFCLDM_01709 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NLIFCLDM_01710 3.2e-78 S Fic/DOC family
NLIFCLDM_01711 5.2e-134 L PLD-like domain
NLIFCLDM_01712 3e-39 L PLD-like domain
NLIFCLDM_01714 2.3e-07 G SMI1 / KNR4 family (SUKH-1)
NLIFCLDM_01715 9.4e-109 L Initiator Replication protein
NLIFCLDM_01716 5.1e-38 S Replication initiator protein A (RepA) N-terminus
NLIFCLDM_01717 5.7e-128 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLIFCLDM_01718 1.6e-37 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NLIFCLDM_01719 2.9e-91 2.7.1.193, 2.7.1.199, 2.7.1.208, 2.7.1.211 G .Experimentally verified through RNA-seq as part of Spo0A regulated transcriptome down-regulated in Spo0A mutant
NLIFCLDM_01720 6e-17 bglG K antiterminator
NLIFCLDM_01721 7.6e-125 D CobQ CobB MinD ParA nucleotide binding domain protein
NLIFCLDM_01723 1.4e-35
NLIFCLDM_01724 0.0 pepN 3.4.11.2 E aminopeptidase
NLIFCLDM_01725 6e-44 2.7.13.3 T protein histidine kinase activity
NLIFCLDM_01726 3e-35 agrA KT Response regulator of the LytR AlgR family
NLIFCLDM_01727 4.4e-21 M domain protein
NLIFCLDM_01728 2.2e-108 XK27_09655 S Virulence protein RhuM family
NLIFCLDM_01729 3.6e-125 yvgN C Aldo keto reductase
NLIFCLDM_01730 7.4e-104 yraQ S Predicted permease
NLIFCLDM_01731 3.1e-62 yeeE S Sulphur transport
NLIFCLDM_01732 5.4e-17 yeeD O Belongs to the sulfur carrier protein TusA family
NLIFCLDM_01733 5e-116 ynjE 2.8.1.11 P Rhodanese Homology Domain
NLIFCLDM_01735 3.6e-234 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
NLIFCLDM_01736 7.1e-26 S Psort location Cytoplasmic, score
NLIFCLDM_01737 4.5e-66 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
NLIFCLDM_01738 4.3e-31 S the current gene model (or a revised gene model) may contain a premature stop
NLIFCLDM_01739 8e-73 prdD S An automated process has identified a potential problem with this gene model
NLIFCLDM_01740 2.7e-66 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
NLIFCLDM_01741 7.8e-143 5.1.1.4 E Proline racemase
NLIFCLDM_01742 2.2e-93 XK27_00825 S Sulfite exporter TauE/SafE
NLIFCLDM_01743 4.1e-223 ybeC E amino acid
NLIFCLDM_01744 1.2e-48 yedF O Belongs to the sulfur carrier protein TusA family
NLIFCLDM_01745 2.9e-07 S Protein of unknown function (DUF3343)
NLIFCLDM_01746 1.4e-137 selB J Elongation factor SelB, winged helix
NLIFCLDM_01747 8.8e-111 sufS 2.8.1.7, 4.4.1.16 E Serine hydroxymethyltransferase
NLIFCLDM_01748 9.1e-110 selA 2.9.1.1 J Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
NLIFCLDM_01749 6.9e-29 yitW S Iron-sulfur cluster assembly protein
NLIFCLDM_01750 4.4e-175 rnfC C RnfC Barrel sandwich hybrid domain
NLIFCLDM_01751 7.8e-100 selD 2.7.9.3 E AIR synthase related protein, C-terminal domain
NLIFCLDM_01752 1.4e-148 yedE S Sulphur transport
NLIFCLDM_01753 1.2e-28 yedF O Belongs to the sulfur carrier protein TusA family
NLIFCLDM_01754 2.9e-16 2.7.1.194, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
NLIFCLDM_01755 2.3e-57 yvbG U MarC family integral membrane protein
NLIFCLDM_01756 6.1e-181 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NLIFCLDM_01757 1.9e-49 S Membrane
NLIFCLDM_01758 2.2e-76 rhaR K helix_turn_helix, arabinose operon control protein
NLIFCLDM_01759 1.5e-188 iolF EGP Major facilitator Superfamily
NLIFCLDM_01760 2.9e-215 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NLIFCLDM_01761 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NLIFCLDM_01762 2.2e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
NLIFCLDM_01763 1.5e-109 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
NLIFCLDM_01765 1.7e-19 S YjcQ protein
NLIFCLDM_01766 7.6e-105 L Belongs to the 'phage' integrase family
NLIFCLDM_01767 5.7e-23 3.1.21.3 V Type I restriction modification DNA specificity domain
NLIFCLDM_01768 1.9e-59 hsdM 2.1.1.72 V type I restriction-modification system
NLIFCLDM_01769 4.3e-26 K Cro/C1-type HTH DNA-binding domain
NLIFCLDM_01770 2.6e-80 S Putative inner membrane protein (DUF1819)
NLIFCLDM_01771 6.9e-69 S Domain of unknown function (DUF1788)
NLIFCLDM_01772 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
NLIFCLDM_01773 0.0 V restriction
NLIFCLDM_01774 3.3e-310 S TIGR02687 family
NLIFCLDM_01775 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
NLIFCLDM_01776 1.1e-49
NLIFCLDM_01777 7.6e-38
NLIFCLDM_01778 1e-09
NLIFCLDM_01779 2.1e-16
NLIFCLDM_01780 5.5e-27
NLIFCLDM_01783 6.2e-167 potE2 E amino acid
NLIFCLDM_01784 4.3e-147 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NLIFCLDM_01785 1e-115 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NLIFCLDM_01786 1.5e-57 racA K Domain of unknown function (DUF1836)
NLIFCLDM_01787 1.7e-79 yitS S EDD domain protein, DegV family
NLIFCLDM_01788 1.1e-45 yjaB_1 K Acetyltransferase (GNAT) domain
NLIFCLDM_01789 8.7e-07
NLIFCLDM_01790 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NLIFCLDM_01791 0.0 O Belongs to the peptidase S8 family
NLIFCLDM_01792 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
NLIFCLDM_01793 2.8e-57 tlpA2 L Transposase IS200 like
NLIFCLDM_01794 1.1e-157 L transposase, IS605 OrfB family
NLIFCLDM_01795 4.6e-84 dps P Ferritin-like domain
NLIFCLDM_01796 1.1e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NLIFCLDM_01797 9.6e-44 L hmm pf00665
NLIFCLDM_01798 5e-18 tnp
NLIFCLDM_01799 8.7e-31 tnp L Transposase IS66 family
NLIFCLDM_01800 1.7e-32 P Heavy-metal-associated domain
NLIFCLDM_01801 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NLIFCLDM_01802 1.3e-20 L PFAM transposase IS3 IS911 family protein
NLIFCLDM_01803 1.4e-41 L Integrase core domain
NLIFCLDM_01804 2.4e-35 L Integrase core domain
NLIFCLDM_01805 3.4e-129 EGP Major Facilitator Superfamily
NLIFCLDM_01806 1.4e-98 EGP Major Facilitator Superfamily
NLIFCLDM_01807 1.3e-72 K Transcriptional regulator, LysR family
NLIFCLDM_01808 1.6e-138 G Xylose isomerase-like TIM barrel
NLIFCLDM_01809 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
NLIFCLDM_01810 1.6e-217 1.3.5.4 C FAD binding domain
NLIFCLDM_01811 1.3e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NLIFCLDM_01812 3.8e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NLIFCLDM_01813 1.1e-142 xerS L Phage integrase family
NLIFCLDM_01817 2e-91 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NLIFCLDM_01818 8.2e-13 ptp3 3.1.3.48 T Tyrosine phosphatase family
NLIFCLDM_01819 8.7e-39 ptp3 3.1.3.48 T Tyrosine phosphatase family
NLIFCLDM_01820 2.4e-75 desR K helix_turn_helix, Lux Regulon
NLIFCLDM_01821 3.2e-57 salK 2.7.13.3 T Histidine kinase
NLIFCLDM_01822 1.9e-53 yvfS V ABC-2 type transporter
NLIFCLDM_01823 2e-78 yvfR V ABC transporter
NLIFCLDM_01824 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NLIFCLDM_01825 1.7e-79 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NLIFCLDM_01826 1.2e-30
NLIFCLDM_01827 8.2e-16
NLIFCLDM_01828 4.7e-112 rssA S Phospholipase, patatin family
NLIFCLDM_01829 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLIFCLDM_01830 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
NLIFCLDM_01831 1.2e-44 S VIT family
NLIFCLDM_01832 8.7e-60 L Transposase
NLIFCLDM_01833 4.2e-240 sufB O assembly protein SufB
NLIFCLDM_01834 1.4e-40 nifU C SUF system FeS assembly protein, NifU family
NLIFCLDM_01835 1.1e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NLIFCLDM_01836 5.6e-143 sufD O FeS assembly protein SufD
NLIFCLDM_01837 8.1e-116 sufC O FeS assembly ATPase SufC
NLIFCLDM_01838 8.7e-221 E ABC transporter, substratebinding protein
NLIFCLDM_01839 8.5e-138 yfeO P Voltage gated chloride channel
NLIFCLDM_01840 1.4e-27 K Helix-turn-helix XRE-family like proteins
NLIFCLDM_01841 5.6e-136 pfoS S Phosphotransferase system, EIIC
NLIFCLDM_01842 7.2e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NLIFCLDM_01843 8.8e-66 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
NLIFCLDM_01844 1.2e-35 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NLIFCLDM_01845 3.9e-134 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
NLIFCLDM_01846 2.2e-83 srlA G PTS system enzyme II sorbitol-specific factor
NLIFCLDM_01847 9.9e-43 gutM K Glucitol operon activator protein (GutM)
NLIFCLDM_01848 2.9e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
NLIFCLDM_01849 3.6e-111 IQ NAD dependent epimerase/dehydratase family
NLIFCLDM_01850 1e-26 yuaG 3.4.21.72 M by MetaGeneAnnotator
NLIFCLDM_01851 1.7e-39 M Phage tail tape measure protein TP901
NLIFCLDM_01855 4.8e-29 S Phage Mu protein F like protein
NLIFCLDM_01856 2.7e-99 fabK 1.3.1.9 S Nitronate monooxygenase
NLIFCLDM_01857 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NLIFCLDM_01859 1.8e-265 fbp 3.1.3.11 G phosphatase activity
NLIFCLDM_01860 2.2e-71 xerD L Phage integrase, N-terminal SAM-like domain
NLIFCLDM_01864 4.6e-51 mesE M Transport protein ComB
NLIFCLDM_01865 8.5e-20 mesE M Transport protein ComB
NLIFCLDM_01866 3.7e-247 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NLIFCLDM_01868 7.9e-77 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NLIFCLDM_01869 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NLIFCLDM_01870 5.6e-120 potB P ABC transporter permease
NLIFCLDM_01871 4.5e-104 potC U Binding-protein-dependent transport system inner membrane component
NLIFCLDM_01872 6.3e-159 potD P ABC transporter
NLIFCLDM_01873 3.5e-132 ABC-SBP S ABC transporter
NLIFCLDM_01874 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NLIFCLDM_01875 8e-108 XK27_08845 S ABC transporter, ATP-binding protein
NLIFCLDM_01876 5.7e-67 M ErfK YbiS YcfS YnhG
NLIFCLDM_01877 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLIFCLDM_01878 1.9e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NLIFCLDM_01879 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NLIFCLDM_01880 1.2e-102 pgm3 G phosphoglycerate mutase
NLIFCLDM_01881 6.8e-55 S CAAX protease self-immunity
NLIFCLDM_01882 1.1e-46 C Flavodoxin
NLIFCLDM_01883 3.6e-54 yphH S Cupin domain
NLIFCLDM_01884 2.6e-44 yphJ 4.1.1.44 S decarboxylase
NLIFCLDM_01885 1.2e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
NLIFCLDM_01886 2.2e-106 metQ1 P Belongs to the nlpA lipoprotein family
NLIFCLDM_01887 4.4e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLIFCLDM_01888 2.7e-70 metI P ABC transporter permease
NLIFCLDM_01889 3.3e-134 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NLIFCLDM_01890 3e-84 drgA C nitroreductase
NLIFCLDM_01891 1e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
NLIFCLDM_01892 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NLIFCLDM_01893 2.4e-171 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NLIFCLDM_01894 5.7e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NLIFCLDM_01903 2.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLIFCLDM_01904 2.4e-31 metI U ABC transporter permease
NLIFCLDM_01905 2.5e-128 metQ M Belongs to the nlpA lipoprotein family
NLIFCLDM_01906 1.9e-58 S Protein of unknown function (DUF4256)
NLIFCLDM_01908 8.5e-110 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
NLIFCLDM_01909 1.6e-301 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
NLIFCLDM_01910 6.6e-234 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
NLIFCLDM_01911 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NLIFCLDM_01912 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NLIFCLDM_01913 1e-179 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NLIFCLDM_01914 4e-230 lpdA 1.8.1.4 C Dehydrogenase
NLIFCLDM_01915 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
NLIFCLDM_01916 4.2e-56 S Protein of unknown function (DUF975)
NLIFCLDM_01917 9.7e-78 E GDSL-like Lipase/Acylhydrolase family
NLIFCLDM_01918 6.1e-39
NLIFCLDM_01919 4.1e-27 gcvR T Belongs to the UPF0237 family
NLIFCLDM_01920 7.9e-220 XK27_08635 S UPF0210 protein
NLIFCLDM_01921 4.5e-87 fruR K DeoR C terminal sensor domain
NLIFCLDM_01922 5.3e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NLIFCLDM_01923 9.6e-283 fruA 2.7.1.202 GT Phosphotransferase System
NLIFCLDM_01924 2e-49 cps3F
NLIFCLDM_01925 2.7e-83 S Membrane
NLIFCLDM_01926 1.8e-254 E Amino acid permease
NLIFCLDM_01927 2.2e-225 cadA P P-type ATPase
NLIFCLDM_01928 6.4e-114 degV S EDD domain protein, DegV family
NLIFCLDM_01929 1.1e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NLIFCLDM_01930 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
NLIFCLDM_01931 5.7e-27 ydiI Q Thioesterase superfamily
NLIFCLDM_01932 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NLIFCLDM_01933 9.6e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NLIFCLDM_01934 1.8e-80 S L,D-transpeptidase catalytic domain
NLIFCLDM_01935 3.7e-164 EGP Major facilitator Superfamily
NLIFCLDM_01936 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
NLIFCLDM_01937 4.6e-226 pipD E Dipeptidase
NLIFCLDM_01938 3.6e-114 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NLIFCLDM_01939 2.6e-32 ywjH S Protein of unknown function (DUF1634)
NLIFCLDM_01940 1.7e-119 yxaA S membrane transporter protein
NLIFCLDM_01941 7.6e-83 lysR5 K LysR substrate binding domain
NLIFCLDM_01942 7.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
NLIFCLDM_01943 1.2e-13 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NLIFCLDM_01944 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NLIFCLDM_01945 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
NLIFCLDM_01946 5.5e-243 lysP E amino acid
NLIFCLDM_01947 2.1e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)