ORF_ID e_value Gene_name EC_number CAZy COGs Description
EKKJOAOI_00001 6.9e-30 yqkB S Belongs to the HesB IscA family
EKKJOAOI_00002 2.3e-65 yxkH G Polysaccharide deacetylase
EKKJOAOI_00003 9.6e-09
EKKJOAOI_00004 2.9e-53 K LysR substrate binding domain
EKKJOAOI_00005 2e-122 MA20_14895 S Conserved hypothetical protein 698
EKKJOAOI_00006 1.1e-199 nupG F Nucleoside
EKKJOAOI_00007 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EKKJOAOI_00008 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EKKJOAOI_00009 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
EKKJOAOI_00010 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EKKJOAOI_00011 3.9e-159 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EKKJOAOI_00012 9e-20 yaaA S S4 domain protein YaaA
EKKJOAOI_00013 9.3e-153 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EKKJOAOI_00014 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKKJOAOI_00015 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EKKJOAOI_00016 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
EKKJOAOI_00017 3.3e-63 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EKKJOAOI_00018 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EKKJOAOI_00019 2.5e-110 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
EKKJOAOI_00020 7.3e-117 S Glycosyl transferase family 2
EKKJOAOI_00021 7.4e-64 D peptidase
EKKJOAOI_00022 0.0 asnB 6.3.5.4 E Asparagine synthase
EKKJOAOI_00023 1.9e-47 yiiE S Protein of unknown function (DUF1211)
EKKJOAOI_00024 7.8e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EKKJOAOI_00025 6.3e-247 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EKKJOAOI_00026 3.6e-17 yneR
EKKJOAOI_00027 8.7e-231 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EKKJOAOI_00028 4.9e-224 yxbA 6.3.1.12 S ATP-grasp enzyme
EKKJOAOI_00029 2.4e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EKKJOAOI_00030 9.9e-153 mdtG EGP Major facilitator Superfamily
EKKJOAOI_00031 1e-14 yobS K transcriptional regulator
EKKJOAOI_00032 2.8e-109 glcU U sugar transport
EKKJOAOI_00033 3.4e-170 yjjP S Putative threonine/serine exporter
EKKJOAOI_00034 1.4e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
EKKJOAOI_00035 3.7e-96 yicL EG EamA-like transporter family
EKKJOAOI_00036 6e-223 pepF E Oligopeptidase F
EKKJOAOI_00037 1.5e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EKKJOAOI_00038 4.9e-178 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EKKJOAOI_00039 6.6e-140 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
EKKJOAOI_00040 4.1e-61 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EKKJOAOI_00041 4e-23 relB L RelB antitoxin
EKKJOAOI_00043 2.9e-172 S Putative peptidoglycan binding domain
EKKJOAOI_00044 1.2e-31 K Transcriptional regulator, MarR family
EKKJOAOI_00045 1.4e-216 XK27_09600 V ABC transporter, ATP-binding protein
EKKJOAOI_00046 1.1e-229 V ABC transporter transmembrane region
EKKJOAOI_00048 9.1e-93 S Domain of unknown function DUF87
EKKJOAOI_00050 7.9e-106 yxeH S hydrolase
EKKJOAOI_00051 9e-114 K response regulator
EKKJOAOI_00052 1.1e-272 vicK 2.7.13.3 T Histidine kinase
EKKJOAOI_00053 4.6e-103 yycH S YycH protein
EKKJOAOI_00054 5.6e-80 yycI S YycH protein
EKKJOAOI_00055 3.1e-30 yyaQ S YjbR
EKKJOAOI_00056 1.3e-116 vicX 3.1.26.11 S domain protein
EKKJOAOI_00057 3.7e-145 htrA 3.4.21.107 O serine protease
EKKJOAOI_00058 1.5e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EKKJOAOI_00059 4.4e-40 1.6.5.2 GM NAD(P)H-binding
EKKJOAOI_00060 3.3e-25 K MarR family transcriptional regulator
EKKJOAOI_00061 5.9e-88 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
EKKJOAOI_00062 2e-46 3.6.4.12 S PD-(D/E)XK nuclease family transposase
EKKJOAOI_00064 9.4e-208 G glycerol-3-phosphate transporter
EKKJOAOI_00065 5.9e-18 L HTH-like domain
EKKJOAOI_00066 8e-37 L Integrase core domain
EKKJOAOI_00067 3.5e-26 L PFAM transposase IS200-family protein
EKKJOAOI_00068 3.8e-93 yihY S Belongs to the UPF0761 family
EKKJOAOI_00069 6.2e-12 mltD CBM50 M Lysin motif
EKKJOAOI_00070 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EKKJOAOI_00071 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
EKKJOAOI_00072 5.1e-54 fld C Flavodoxin
EKKJOAOI_00073 8.7e-53 gtcA S Teichoic acid glycosylation protein
EKKJOAOI_00074 0.0 S Bacterial membrane protein YfhO
EKKJOAOI_00075 5.2e-120 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
EKKJOAOI_00076 1.7e-122 S Sulfite exporter TauE/SafE
EKKJOAOI_00077 2.4e-70 K Sugar-specific transcriptional regulator TrmB
EKKJOAOI_00078 1e-167 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EKKJOAOI_00079 6e-182 pepS E Thermophilic metalloprotease (M29)
EKKJOAOI_00080 3e-266 E Amino acid permease
EKKJOAOI_00081 4.9e-85 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
EKKJOAOI_00082 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
EKKJOAOI_00083 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
EKKJOAOI_00084 4.3e-213 malT G Transporter, major facilitator family protein
EKKJOAOI_00085 4.7e-100 malR K Transcriptional regulator, LacI family
EKKJOAOI_00086 2.3e-279 kup P Transport of potassium into the cell
EKKJOAOI_00088 2e-20 S Domain of unknown function (DUF3284)
EKKJOAOI_00089 5.2e-160 yfmL L DEAD DEAH box helicase
EKKJOAOI_00090 1.6e-127 mocA S Oxidoreductase
EKKJOAOI_00091 2e-24 S Domain of unknown function (DUF4828)
EKKJOAOI_00092 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
EKKJOAOI_00093 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EKKJOAOI_00094 4.7e-194 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
EKKJOAOI_00095 1.4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
EKKJOAOI_00096 7.1e-161 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EKKJOAOI_00097 3.6e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EKKJOAOI_00098 8.5e-222 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
EKKJOAOI_00099 1.1e-41 O ADP-ribosylglycohydrolase
EKKJOAOI_00100 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
EKKJOAOI_00101 2.9e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
EKKJOAOI_00102 1.3e-34 K GNAT family
EKKJOAOI_00103 1.7e-40
EKKJOAOI_00105 2.1e-159 mgtE P Acts as a magnesium transporter
EKKJOAOI_00106 9.7e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
EKKJOAOI_00107 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EKKJOAOI_00108 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
EKKJOAOI_00109 2.7e-259 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
EKKJOAOI_00110 9.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
EKKJOAOI_00111 9.7e-194 pbuX F xanthine permease
EKKJOAOI_00112 3.3e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EKKJOAOI_00113 4.1e-60 acmC 3.2.1.96 NU mannosyl-glycoprotein
EKKJOAOI_00114 9.4e-64 S ECF transporter, substrate-specific component
EKKJOAOI_00115 3.3e-127 mleP S Sodium Bile acid symporter family
EKKJOAOI_00116 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
EKKJOAOI_00117 6.2e-72 mleR K LysR family
EKKJOAOI_00118 1.1e-56 K transcriptional
EKKJOAOI_00119 3.4e-41 K Bacterial regulatory proteins, tetR family
EKKJOAOI_00120 1.8e-59 T Belongs to the universal stress protein A family
EKKJOAOI_00121 3.6e-44 K Copper transport repressor CopY TcrY
EKKJOAOI_00122 3.5e-230 3.2.1.18 GH33 M Rib/alpha-like repeat
EKKJOAOI_00124 1.8e-95 ypuA S Protein of unknown function (DUF1002)
EKKJOAOI_00125 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
EKKJOAOI_00126 3e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EKKJOAOI_00127 8.7e-35 yncA 2.3.1.79 S Maltose acetyltransferase
EKKJOAOI_00128 6.9e-206 yflS P Sodium:sulfate symporter transmembrane region
EKKJOAOI_00129 1.2e-199 frdC 1.3.5.4 C FAD binding domain
EKKJOAOI_00130 3.3e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EKKJOAOI_00131 2e-14 ybaN S Protein of unknown function (DUF454)
EKKJOAOI_00132 8.2e-177 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
EKKJOAOI_00133 2.6e-57 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EKKJOAOI_00134 3.6e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EKKJOAOI_00135 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EKKJOAOI_00136 1.1e-71 ywlG S Belongs to the UPF0340 family
EKKJOAOI_00137 7.3e-67 S Acetyltransferase (GNAT) domain
EKKJOAOI_00138 1.6e-13 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EKKJOAOI_00141 2.3e-173 spoVK O PFAM ATPase family associated with various cellular activities (AAA)
EKKJOAOI_00142 3e-230 yfjM S Protein of unknown function DUF262
EKKJOAOI_00143 8.5e-73 S Domain of unknown function (DUF3841)
EKKJOAOI_00144 1.6e-56 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
EKKJOAOI_00145 4.2e-302 hsdM 2.1.1.72 V Type I restriction-modification system
EKKJOAOI_00146 1.4e-208 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKKJOAOI_00147 3.4e-146 yegS 2.7.1.107 G Lipid kinase
EKKJOAOI_00148 1.9e-256 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKKJOAOI_00149 3.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EKKJOAOI_00150 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EKKJOAOI_00151 1.2e-160 camS S sex pheromone
EKKJOAOI_00152 3.9e-279 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EKKJOAOI_00153 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EKKJOAOI_00154 4.2e-145 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EKKJOAOI_00159 5.1e-260 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EKKJOAOI_00160 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EKKJOAOI_00161 2.4e-132 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EKKJOAOI_00162 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EKKJOAOI_00163 1.5e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EKKJOAOI_00164 5.5e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EKKJOAOI_00165 1.1e-40 yabR J RNA binding
EKKJOAOI_00166 1.3e-21 divIC D Septum formation initiator
EKKJOAOI_00167 3.6e-31 yabO J S4 domain protein
EKKJOAOI_00168 7.3e-140 yabM S Polysaccharide biosynthesis protein
EKKJOAOI_00169 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EKKJOAOI_00170 6.5e-75 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EKKJOAOI_00171 6.2e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EKKJOAOI_00172 2.5e-86 S (CBS) domain
EKKJOAOI_00173 4e-141 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EKKJOAOI_00174 3.2e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EKKJOAOI_00175 1e-51 perR P Belongs to the Fur family
EKKJOAOI_00176 7.6e-58 S LexA-binding, inner membrane-associated putative hydrolase
EKKJOAOI_00177 6.7e-97 sbcC L Putative exonuclease SbcCD, C subunit
EKKJOAOI_00178 1.1e-113 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EKKJOAOI_00179 2.1e-36 M LysM domain protein
EKKJOAOI_00180 3e-278 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EKKJOAOI_00181 7e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EKKJOAOI_00182 2e-35 ygfC K Bacterial regulatory proteins, tetR family
EKKJOAOI_00183 5.9e-101 hrtB V ABC transporter permease
EKKJOAOI_00184 1.5e-86 devA 3.6.3.25 V ABC transporter, ATP-binding protein
EKKJOAOI_00185 3e-67 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EKKJOAOI_00186 0.0 helD 3.6.4.12 L DNA helicase
EKKJOAOI_00187 8.9e-246 yjbQ P TrkA C-terminal domain protein
EKKJOAOI_00188 3.4e-23
EKKJOAOI_00189 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
EKKJOAOI_00190 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EKKJOAOI_00191 2.5e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EKKJOAOI_00192 2.8e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKKJOAOI_00193 6.7e-111 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKKJOAOI_00194 1.8e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EKKJOAOI_00195 4.8e-53 rplQ J Ribosomal protein L17
EKKJOAOI_00196 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKKJOAOI_00197 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EKKJOAOI_00198 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EKKJOAOI_00199 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EKKJOAOI_00200 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EKKJOAOI_00201 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EKKJOAOI_00202 4.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EKKJOAOI_00203 1e-67 rplO J Binds to the 23S rRNA
EKKJOAOI_00204 2.1e-22 rpmD J Ribosomal protein L30
EKKJOAOI_00205 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EKKJOAOI_00206 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EKKJOAOI_00207 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EKKJOAOI_00208 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EKKJOAOI_00209 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKKJOAOI_00210 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EKKJOAOI_00211 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EKKJOAOI_00212 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EKKJOAOI_00213 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EKKJOAOI_00214 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
EKKJOAOI_00215 6.2e-73 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EKKJOAOI_00216 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EKKJOAOI_00217 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EKKJOAOI_00218 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EKKJOAOI_00219 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EKKJOAOI_00220 2.9e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EKKJOAOI_00221 1e-100 rplD J Forms part of the polypeptide exit tunnel
EKKJOAOI_00222 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EKKJOAOI_00223 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EKKJOAOI_00224 5.6e-167 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EKKJOAOI_00225 2.5e-78 K rpiR family
EKKJOAOI_00226 5.9e-54 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
EKKJOAOI_00227 1.1e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
EKKJOAOI_00228 6.5e-21 K Acetyltransferase (GNAT) domain
EKKJOAOI_00229 2.9e-182 steT E amino acid
EKKJOAOI_00230 9.6e-78 glnP P ABC transporter permease
EKKJOAOI_00231 1.2e-85 gluC P ABC transporter permease
EKKJOAOI_00232 6.6e-100 glnH ET ABC transporter
EKKJOAOI_00233 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EKKJOAOI_00234 3.9e-08
EKKJOAOI_00235 2.2e-98
EKKJOAOI_00237 3.2e-53 zur P Belongs to the Fur family
EKKJOAOI_00238 2.2e-212 yfnA E Amino Acid
EKKJOAOI_00239 9.6e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EKKJOAOI_00240 0.0 L Helicase C-terminal domain protein
EKKJOAOI_00241 6e-79 ptp2 3.1.3.48 T Tyrosine phosphatase family
EKKJOAOI_00242 2.1e-180 yhdP S Transporter associated domain
EKKJOAOI_00243 1.7e-26
EKKJOAOI_00244 5.3e-74 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EKKJOAOI_00245 3.7e-131 bacI V MacB-like periplasmic core domain
EKKJOAOI_00246 7.4e-97 V ABC transporter
EKKJOAOI_00247 2.6e-64 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EKKJOAOI_00248 1.4e-156 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
EKKJOAOI_00249 6.2e-140 V MatE
EKKJOAOI_00250 3.5e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKKJOAOI_00251 2.1e-85 S Alpha beta hydrolase
EKKJOAOI_00252 7.1e-95 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EKKJOAOI_00253 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EKKJOAOI_00254 1e-111 argE 3.5.1.18 E Peptidase dimerisation domain
EKKJOAOI_00255 8.4e-102 IQ Enoyl-(Acyl carrier protein) reductase
EKKJOAOI_00256 3.9e-34 XK27_01315 S Protein of unknown function (DUF2829)
EKKJOAOI_00257 8.1e-53 queT S QueT transporter
EKKJOAOI_00259 1.1e-65 degV S Uncharacterised protein, DegV family COG1307
EKKJOAOI_00260 8.8e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKKJOAOI_00261 9.4e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EKKJOAOI_00262 3.2e-34 trxA O Belongs to the thioredoxin family
EKKJOAOI_00263 1.4e-86 S Sucrose-6F-phosphate phosphohydrolase
EKKJOAOI_00264 2.8e-125 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EKKJOAOI_00265 2.8e-49 S Threonine/Serine exporter, ThrE
EKKJOAOI_00266 4.3e-82 thrE S Putative threonine/serine exporter
EKKJOAOI_00267 3.1e-27 cspC K Cold shock protein
EKKJOAOI_00268 8.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
EKKJOAOI_00269 3.8e-93 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EKKJOAOI_00270 5.4e-23
EKKJOAOI_00271 1.2e-58 3.6.1.27 I phosphatase
EKKJOAOI_00272 1.2e-24
EKKJOAOI_00273 1.8e-65 I alpha/beta hydrolase fold
EKKJOAOI_00274 1.3e-38 azlD S branched-chain amino acid
EKKJOAOI_00275 1.1e-104 azlC E AzlC protein
EKKJOAOI_00276 1.3e-16
EKKJOAOI_00277 1.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
EKKJOAOI_00278 3.8e-99 V domain protein
EKKJOAOI_00279 1.9e-09
EKKJOAOI_00281 6e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EKKJOAOI_00282 5.4e-172 malY 4.4.1.8 E Aminotransferase, class I
EKKJOAOI_00283 2.4e-118 K AI-2E family transporter
EKKJOAOI_00284 5.2e-61 EG EamA-like transporter family
EKKJOAOI_00285 1.1e-75 L haloacid dehalogenase-like hydrolase
EKKJOAOI_00286 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EKKJOAOI_00287 1.8e-67 1.5.1.38 S NADPH-dependent FMN reductase
EKKJOAOI_00288 3.7e-164 C Luciferase-like monooxygenase
EKKJOAOI_00289 1.3e-41 K Transcriptional regulator, HxlR family
EKKJOAOI_00290 1.7e-171 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EKKJOAOI_00291 6.2e-102 ydhQ K UbiC transcription regulator-associated domain protein
EKKJOAOI_00292 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
EKKJOAOI_00293 2.4e-82 pncA Q isochorismatase
EKKJOAOI_00294 3.5e-63 3.1.3.73 G phosphoglycerate mutase
EKKJOAOI_00295 4e-104 treB G phosphotransferase system
EKKJOAOI_00296 1.1e-147 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
EKKJOAOI_00297 1.9e-167 mdtG EGP Major facilitator Superfamily
EKKJOAOI_00299 1.8e-195 XK27_08315 M Sulfatase
EKKJOAOI_00300 1.8e-47 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EKKJOAOI_00301 5.6e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EKKJOAOI_00302 8.8e-168 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EKKJOAOI_00303 3.4e-127 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EKKJOAOI_00304 4.1e-177 thrC 4.2.3.1 E Threonine synthase
EKKJOAOI_00305 9.7e-75 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EKKJOAOI_00306 6.2e-62 S Psort location CytoplasmicMembrane, score
EKKJOAOI_00307 1.3e-87 waaB GT4 M Glycosyl transferases group 1
EKKJOAOI_00308 1.4e-58 cps3F
EKKJOAOI_00309 5.3e-70 M Domain of unknown function (DUF4422)
EKKJOAOI_00310 4.8e-161 XK27_08315 M Sulfatase
EKKJOAOI_00311 6.5e-130 S Bacterial membrane protein YfhO
EKKJOAOI_00312 3.6e-14
EKKJOAOI_00313 1.4e-54 cps3I G Acyltransferase family
EKKJOAOI_00314 1.1e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EKKJOAOI_00315 4.4e-39 2.7.7.65 T phosphorelay sensor kinase activity
EKKJOAOI_00316 1.1e-157 XK27_09615 S reductase
EKKJOAOI_00317 1.9e-67 XK27_09620 S NADPH-dependent FMN reductase
EKKJOAOI_00318 1.8e-95 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EKKJOAOI_00319 2.8e-160 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EKKJOAOI_00320 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EKKJOAOI_00321 1e-74 G Peptidase_C39 like family
EKKJOAOI_00322 8.3e-48 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKKJOAOI_00323 1e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EKKJOAOI_00324 2.3e-133 coaA 2.7.1.33 F Pantothenic acid kinase
EKKJOAOI_00325 3.5e-42 E lipolytic protein G-D-S-L family
EKKJOAOI_00326 2.3e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EKKJOAOI_00327 2.1e-189 glnPH2 P ABC transporter permease
EKKJOAOI_00328 2.1e-213 yjeM E Amino Acid
EKKJOAOI_00329 1.8e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
EKKJOAOI_00330 5.1e-138 tetA EGP Major facilitator Superfamily
EKKJOAOI_00332 2.3e-70 rny D Peptidase family M23
EKKJOAOI_00333 8.5e-188 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
EKKJOAOI_00334 1.1e-193 glf 5.4.99.9 M UDP-galactopyranose mutase
EKKJOAOI_00335 1.8e-116 M Core-2/I-Branching enzyme
EKKJOAOI_00336 8.5e-90 rfbP M Bacterial sugar transferase
EKKJOAOI_00337 3.7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EKKJOAOI_00338 8.6e-110 ywqE 3.1.3.48 GM PHP domain protein
EKKJOAOI_00339 1.2e-81 ywqD 2.7.10.1 D Capsular exopolysaccharide family
EKKJOAOI_00340 3e-73 epsB M biosynthesis protein
EKKJOAOI_00342 2.7e-114 cps2J S Polysaccharide biosynthesis protein
EKKJOAOI_00343 1.2e-67 S Polysaccharide pyruvyl transferase
EKKJOAOI_00345 4.5e-28 M family 8
EKKJOAOI_00346 6.5e-59
EKKJOAOI_00347 5.9e-37 M group 2 family protein
EKKJOAOI_00348 1e-91 M Glycosyl transferase family 8
EKKJOAOI_00349 5.9e-114 3.6.4.12 L UvrD/REP helicase N-terminal domain
EKKJOAOI_00350 4.8e-144 L AAA ATPase domain
EKKJOAOI_00351 4.9e-79 S response to antibiotic
EKKJOAOI_00352 9.8e-27 S zinc-ribbon domain
EKKJOAOI_00353 1.6e-117 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
EKKJOAOI_00354 2.1e-130 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EKKJOAOI_00355 5.6e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EKKJOAOI_00356 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EKKJOAOI_00357 1.9e-142 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EKKJOAOI_00358 1.7e-62 S Glycosyltransferase like family 2
EKKJOAOI_00359 2.2e-116 cps1D M Domain of unknown function (DUF4422)
EKKJOAOI_00360 7.3e-38 S CAAX protease self-immunity
EKKJOAOI_00361 1e-87 yvyE 3.4.13.9 S YigZ family
EKKJOAOI_00362 3.3e-57 S Haloacid dehalogenase-like hydrolase
EKKJOAOI_00363 3.4e-154 EGP Major facilitator Superfamily
EKKJOAOI_00365 2.2e-66 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
EKKJOAOI_00366 1.2e-27 yraB K transcriptional regulator
EKKJOAOI_00367 9.8e-90 S NADPH-dependent FMN reductase
EKKJOAOI_00368 1.7e-100 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EKKJOAOI_00369 8.6e-56 S ECF transporter, substrate-specific component
EKKJOAOI_00370 2.8e-95 znuB U ABC 3 transport family
EKKJOAOI_00371 1e-98 fhuC P ABC transporter
EKKJOAOI_00372 5.1e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
EKKJOAOI_00373 1.3e-40
EKKJOAOI_00374 5e-51 I Alpha/beta hydrolase family
EKKJOAOI_00375 1.8e-94 S Bacterial membrane protein, YfhO
EKKJOAOI_00376 5.5e-53 XK27_01040 S Protein of unknown function (DUF1129)
EKKJOAOI_00377 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EKKJOAOI_00378 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
EKKJOAOI_00379 1.4e-108 spo0J K Belongs to the ParB family
EKKJOAOI_00380 6.5e-118 soj D Sporulation initiation inhibitor
EKKJOAOI_00381 3.7e-82 noc K Belongs to the ParB family
EKKJOAOI_00382 1.1e-101 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
EKKJOAOI_00383 4.1e-127 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EKKJOAOI_00384 2.7e-108 3.1.4.46 C phosphodiesterase
EKKJOAOI_00385 0.0 pacL 3.6.3.8 P P-type ATPase
EKKJOAOI_00386 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
EKKJOAOI_00387 1.8e-72 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
EKKJOAOI_00389 2.3e-63 srtA 3.4.22.70 M sortase family
EKKJOAOI_00390 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EKKJOAOI_00391 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EKKJOAOI_00392 3.7e-34
EKKJOAOI_00393 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EKKJOAOI_00394 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EKKJOAOI_00395 6.6e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EKKJOAOI_00396 4.7e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
EKKJOAOI_00397 1.1e-39 ybjQ S Belongs to the UPF0145 family
EKKJOAOI_00398 2.5e-08
EKKJOAOI_00399 8e-96 V ABC transporter, ATP-binding protein
EKKJOAOI_00400 1.1e-41 gntR1 K Transcriptional regulator, GntR family
EKKJOAOI_00401 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
EKKJOAOI_00402 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKKJOAOI_00403 4.2e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
EKKJOAOI_00404 2.2e-107 terC P Integral membrane protein TerC family
EKKJOAOI_00405 1.6e-38 K Transcriptional regulator
EKKJOAOI_00406 5.7e-96 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EKKJOAOI_00407 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EKKJOAOI_00408 4.5e-102 tcyB E ABC transporter
EKKJOAOI_00409 3.2e-29 ponA V the current gene model (or a revised gene model) may contain a frame shift
EKKJOAOI_00410 4.7e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
EKKJOAOI_00411 1.5e-301 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EKKJOAOI_00412 2e-209 mtlR K Mga helix-turn-helix domain
EKKJOAOI_00413 7.5e-177 yjcE P Sodium proton antiporter
EKKJOAOI_00414 8.4e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EKKJOAOI_00415 4e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
EKKJOAOI_00416 9.5e-69 dhaL 2.7.1.121 S Dak2
EKKJOAOI_00417 2e-151 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
EKKJOAOI_00418 9.3e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
EKKJOAOI_00419 1.7e-61 K Bacterial regulatory proteins, tetR family
EKKJOAOI_00420 3.2e-208 brnQ U Component of the transport system for branched-chain amino acids
EKKJOAOI_00422 3.7e-111 endA F DNA RNA non-specific endonuclease
EKKJOAOI_00423 4.1e-75 XK27_02070 S Nitroreductase family
EKKJOAOI_00424 3.1e-193 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
EKKJOAOI_00425 3.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
EKKJOAOI_00426 5.2e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
EKKJOAOI_00427 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
EKKJOAOI_00428 9.3e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
EKKJOAOI_00429 5.1e-77 azlC E branched-chain amino acid
EKKJOAOI_00430 2e-31 azlD S Branched-chain amino acid transport protein (AzlD)
EKKJOAOI_00431 1.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
EKKJOAOI_00432 1.6e-55 jag S R3H domain protein
EKKJOAOI_00433 1.2e-123 sip L Belongs to the 'phage' integrase family
EKKJOAOI_00434 1.4e-24 K Cro/C1-type HTH DNA-binding domain
EKKJOAOI_00435 2.5e-08 S Helix-turn-helix domain
EKKJOAOI_00437 6.8e-39 K COG3617 Prophage antirepressor
EKKJOAOI_00442 6.7e-15
EKKJOAOI_00443 3.1e-43 L Bifunctional DNA primase/polymerase, N-terminal
EKKJOAOI_00444 1e-76 S DNA primase
EKKJOAOI_00446 1.1e-08
EKKJOAOI_00449 6.9e-54 K Transcriptional regulator C-terminal region
EKKJOAOI_00450 7.7e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
EKKJOAOI_00451 2.6e-285 pepO 3.4.24.71 O Peptidase family M13
EKKJOAOI_00452 1.7e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
EKKJOAOI_00453 1.7e-09 yvaZ S Protein of unknown function (DUF1648)
EKKJOAOI_00454 2.1e-69 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
EKKJOAOI_00455 3.9e-47 hmpT S ECF-type riboflavin transporter, S component
EKKJOAOI_00456 5.1e-42 wecD K Acetyltransferase GNAT Family
EKKJOAOI_00458 2.5e-254 XK27_06780 V ABC transporter permease
EKKJOAOI_00459 6.4e-96 XK27_06785 V ABC transporter, ATP-binding protein
EKKJOAOI_00461 7.5e-72 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKKJOAOI_00462 6.9e-121 ytbE S reductase
EKKJOAOI_00463 4.2e-43 ytcD K HxlR-like helix-turn-helix
EKKJOAOI_00464 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
EKKJOAOI_00465 2e-67 ybbL S ABC transporter
EKKJOAOI_00466 8.1e-163 oxlT P Major Facilitator Superfamily
EKKJOAOI_00467 6.2e-53 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EKKJOAOI_00468 3.1e-47 S Short repeat of unknown function (DUF308)
EKKJOAOI_00469 1.4e-30 tetR K Transcriptional regulator C-terminal region
EKKJOAOI_00470 1.2e-150 yfeX P Peroxidase
EKKJOAOI_00471 2.5e-16 S Protein of unknown function (DUF3021)
EKKJOAOI_00472 4.5e-39 K LytTr DNA-binding domain
EKKJOAOI_00473 7.6e-113 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
EKKJOAOI_00474 8.4e-209 mmuP E amino acid
EKKJOAOI_00475 1.2e-15 psiE S Phosphate-starvation-inducible E
EKKJOAOI_00476 3.7e-155 oppF P Belongs to the ABC transporter superfamily
EKKJOAOI_00477 7.4e-181 oppD P Belongs to the ABC transporter superfamily
EKKJOAOI_00478 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKKJOAOI_00479 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
EKKJOAOI_00480 1.1e-202 oppA E ABC transporter, substratebinding protein
EKKJOAOI_00481 1.2e-218 yifK E Amino acid permease
EKKJOAOI_00482 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EKKJOAOI_00483 5.1e-57 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
EKKJOAOI_00484 6.5e-66 pgm3 G phosphoglycerate mutase family
EKKJOAOI_00485 1.3e-252 ctpA 3.6.3.54 P P-type ATPase
EKKJOAOI_00486 1.9e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EKKJOAOI_00487 6.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EKKJOAOI_00488 5.6e-150 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EKKJOAOI_00489 5.3e-134 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
EKKJOAOI_00490 4.3e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EKKJOAOI_00491 8.6e-141 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EKKJOAOI_00492 1.6e-201 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
EKKJOAOI_00493 2.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
EKKJOAOI_00494 1.2e-197 1.3.5.4 C FMN_bind
EKKJOAOI_00495 2.2e-56 3.1.3.48 K Transcriptional regulator
EKKJOAOI_00496 3.8e-161 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
EKKJOAOI_00497 4.5e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
EKKJOAOI_00498 3.7e-74 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EKKJOAOI_00499 9.3e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
EKKJOAOI_00500 1.6e-100 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EKKJOAOI_00501 2.8e-81 S Belongs to the UPF0246 family
EKKJOAOI_00502 5.6e-10 S CAAX protease self-immunity
EKKJOAOI_00503 3.5e-59 ykhA 3.1.2.20 I Thioesterase superfamily
EKKJOAOI_00504 8.7e-157 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EKKJOAOI_00506 7.4e-231 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EKKJOAOI_00507 5.3e-64 C FMN binding
EKKJOAOI_00508 1.3e-204 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EKKJOAOI_00509 1.7e-54 rplI J Binds to the 23S rRNA
EKKJOAOI_00510 2.3e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EKKJOAOI_00511 3.6e-07
EKKJOAOI_00512 8.8e-50 yugI 5.3.1.9 J general stress protein
EKKJOAOI_00513 5.5e-96 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EKKJOAOI_00514 5.1e-92 dedA S SNARE associated Golgi protein
EKKJOAOI_00515 7.8e-32 S Protein of unknown function (DUF1461)
EKKJOAOI_00516 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EKKJOAOI_00517 1.9e-53 yutD S Protein of unknown function (DUF1027)
EKKJOAOI_00518 3e-57 S Calcineurin-like phosphoesterase
EKKJOAOI_00519 1.6e-183 cycA E Amino acid permease
EKKJOAOI_00520 7.6e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
EKKJOAOI_00522 5.5e-11 S Putative Competence protein ComGF
EKKJOAOI_00524 1.5e-13
EKKJOAOI_00525 1.2e-27 comGC U competence protein ComGC
EKKJOAOI_00526 5.7e-98 comGB NU type II secretion system
EKKJOAOI_00527 4.7e-121 comGA NU Type II IV secretion system protein
EKKJOAOI_00528 2.3e-101 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EKKJOAOI_00529 1.5e-119 yebC K Transcriptional regulatory protein
EKKJOAOI_00530 3.7e-42 S VanZ like family
EKKJOAOI_00531 1.3e-158 ccpA K catabolite control protein A
EKKJOAOI_00532 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EKKJOAOI_00533 1.5e-13
EKKJOAOI_00536 1.7e-74 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKKJOAOI_00537 2.1e-34 K helix_turn_helix, Arsenical Resistance Operon Repressor
EKKJOAOI_00538 2.3e-65 hly S protein, hemolysin III
EKKJOAOI_00539 2.5e-41 M1-874 K Domain of unknown function (DUF1836)
EKKJOAOI_00540 1.8e-82 S membrane
EKKJOAOI_00541 9.2e-79 S VIT family
EKKJOAOI_00542 6.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
EKKJOAOI_00543 2.7e-56 P Plays a role in the regulation of phosphate uptake
EKKJOAOI_00544 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EKKJOAOI_00545 4.5e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EKKJOAOI_00546 5.1e-122 pstA P Phosphate transport system permease protein PstA
EKKJOAOI_00547 4.1e-119 pstC P probably responsible for the translocation of the substrate across the membrane
EKKJOAOI_00548 6.4e-98 pstS P Phosphate
EKKJOAOI_00549 1e-41 yjbH Q Thioredoxin
EKKJOAOI_00550 1.9e-232 pepF E oligoendopeptidase F
EKKJOAOI_00551 1.1e-68 coiA 3.6.4.12 S Competence protein
EKKJOAOI_00552 1.2e-47 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EKKJOAOI_00553 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
EKKJOAOI_00565 1.1e-216 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EKKJOAOI_00566 7.2e-149 mepA V MATE efflux family protein
EKKJOAOI_00567 5.6e-150 lsa S ABC transporter
EKKJOAOI_00568 4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EKKJOAOI_00569 6.8e-109 puuD S peptidase C26
EKKJOAOI_00570 9.8e-202 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EKKJOAOI_00571 1.1e-25
EKKJOAOI_00572 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
EKKJOAOI_00573 2.9e-60 uspA T Universal stress protein family
EKKJOAOI_00575 4.7e-210 glnP P ABC transporter
EKKJOAOI_00576 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EKKJOAOI_00577 3.5e-23 L PLD-like domain
EKKJOAOI_00578 6.5e-12 L PLD-like domain
EKKJOAOI_00580 6.1e-08 yokH G regulation of fungal-type cell wall biogenesis
EKKJOAOI_00581 9.4e-109 L Initiator Replication protein
EKKJOAOI_00582 1.9e-37 S Replication initiator protein A (RepA) N-terminus
EKKJOAOI_00583 8.5e-141 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EKKJOAOI_00584 3.2e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EKKJOAOI_00585 1.4e-12 bglG K antiterminator
EKKJOAOI_00586 2.9e-124 D CobQ CobB MinD ParA nucleotide binding domain protein
EKKJOAOI_00588 1.1e-35
EKKJOAOI_00589 0.0 pepN 3.4.11.2 E aminopeptidase
EKKJOAOI_00590 1.8e-43 2.7.13.3 T protein histidine kinase activity
EKKJOAOI_00591 1.6e-22 agrA KT Response regulator of the LytR AlgR family
EKKJOAOI_00593 1.3e-16 M domain protein
EKKJOAOI_00598 3.6e-125 yvgN C Aldo keto reductase
EKKJOAOI_00599 1.7e-122 yvgN C Aldo keto reductase
EKKJOAOI_00600 2.2e-70 K DeoR C terminal sensor domain
EKKJOAOI_00601 1.1e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
EKKJOAOI_00602 3.4e-41 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
EKKJOAOI_00603 1.2e-216 pts36C G PTS system sugar-specific permease component
EKKJOAOI_00605 2.3e-104 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
EKKJOAOI_00607 6.2e-29 S COG NOG19168 non supervised orthologous group
EKKJOAOI_00608 1.1e-189 XK27_11280 S Psort location CytoplasmicMembrane, score
EKKJOAOI_00609 2.7e-14 L Plasmid pRiA4b ORF-3-like protein
EKKJOAOI_00610 1.5e-105 L Belongs to the 'phage' integrase family
EKKJOAOI_00611 5.7e-23 3.1.21.3 V Type I restriction modification DNA specificity domain
EKKJOAOI_00612 8.6e-60 hsdM 2.1.1.72 V type I restriction-modification system
EKKJOAOI_00614 7.8e-54 sthIM 2.1.1.72 L DNA methylase
EKKJOAOI_00615 6.3e-109 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
EKKJOAOI_00616 7.6e-57 sthIM 2.1.1.72 L DNA methylase
EKKJOAOI_00617 4.6e-194 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
EKKJOAOI_00618 8.5e-56 sthIM 2.1.1.72 L DNA methylase
EKKJOAOI_00619 3.1e-116 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
EKKJOAOI_00620 4e-260 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
EKKJOAOI_00621 4.6e-16
EKKJOAOI_00622 4.9e-24
EKKJOAOI_00623 3.4e-48 L HNH endonuclease
EKKJOAOI_00626 3.5e-133 potE2 E amino acid
EKKJOAOI_00627 4.8e-71 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EKKJOAOI_00628 2.3e-69 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EKKJOAOI_00629 7.2e-117 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EKKJOAOI_00630 1.9e-57 racA K Domain of unknown function (DUF1836)
EKKJOAOI_00631 3.1e-81 yitS S EDD domain protein, DegV family
EKKJOAOI_00632 1.7e-46 yjaB_1 K Acetyltransferase (GNAT) domain
EKKJOAOI_00635 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EKKJOAOI_00636 0.0 O Belongs to the peptidase S8 family
EKKJOAOI_00637 4.1e-53 1.14.12.17 C Oxidoreductase NAD-binding domain
EKKJOAOI_00638 2.5e-58 tlpA2 L Transposase IS200 like
EKKJOAOI_00639 1.1e-157 L transposase, IS605 OrfB family
EKKJOAOI_00640 4.6e-84 dps P Ferritin-like domain
EKKJOAOI_00641 1.1e-124 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
EKKJOAOI_00642 9.6e-44 L hmm pf00665
EKKJOAOI_00643 5e-18 tnp
EKKJOAOI_00644 8.7e-31 tnp L Transposase IS66 family
EKKJOAOI_00645 1.7e-32 P Heavy-metal-associated domain
EKKJOAOI_00646 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
EKKJOAOI_00647 1.3e-20 L PFAM transposase IS3 IS911 family protein
EKKJOAOI_00648 1.4e-41 L Integrase core domain
EKKJOAOI_00649 2.4e-35 L Integrase core domain
EKKJOAOI_00650 7.5e-129 EGP Major Facilitator Superfamily
EKKJOAOI_00651 1.4e-98 EGP Major Facilitator Superfamily
EKKJOAOI_00652 7.5e-73 K Transcriptional regulator, LysR family
EKKJOAOI_00653 4.7e-138 G Xylose isomerase-like TIM barrel
EKKJOAOI_00654 4.6e-117 IQ Enoyl-(Acyl carrier protein) reductase
EKKJOAOI_00655 4e-216 1.3.5.4 C FAD binding domain
EKKJOAOI_00656 6.5e-138 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EKKJOAOI_00657 1e-70 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EKKJOAOI_00658 4.2e-142 xerS L Phage integrase family
EKKJOAOI_00662 1.1e-20 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
EKKJOAOI_00663 2.5e-82 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
EKKJOAOI_00664 8.2e-13 ptp3 3.1.3.48 T Tyrosine phosphatase family
EKKJOAOI_00665 8.7e-39 ptp3 3.1.3.48 T Tyrosine phosphatase family
EKKJOAOI_00666 2.4e-75 desR K helix_turn_helix, Lux Regulon
EKKJOAOI_00667 8.4e-58 salK 2.7.13.3 T Histidine kinase
EKKJOAOI_00668 3.2e-53 yvfS V ABC-2 type transporter
EKKJOAOI_00669 3.4e-78 yvfR V ABC transporter
EKKJOAOI_00670 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EKKJOAOI_00671 1.9e-78 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EKKJOAOI_00672 2.7e-30
EKKJOAOI_00673 3.7e-16
EKKJOAOI_00674 3e-111 rssA S Phospholipase, patatin family
EKKJOAOI_00675 1.5e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EKKJOAOI_00676 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
EKKJOAOI_00677 5.5e-45 S VIT family
EKKJOAOI_00678 4.2e-240 sufB O assembly protein SufB
EKKJOAOI_00679 4.9e-41 nifU C SUF system FeS assembly protein, NifU family
EKKJOAOI_00680 3.7e-147 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EKKJOAOI_00681 4.6e-145 sufD O FeS assembly protein SufD
EKKJOAOI_00682 1.1e-115 sufC O FeS assembly ATPase SufC
EKKJOAOI_00683 1.7e-224 E ABC transporter, substratebinding protein
EKKJOAOI_00684 2.5e-255 V Type II restriction enzyme, methylase subunits
EKKJOAOI_00685 5.6e-136 pfoS S Phosphotransferase system, EIIC
EKKJOAOI_00686 5.5e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
EKKJOAOI_00687 6.3e-64 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
EKKJOAOI_00688 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
EKKJOAOI_00689 1.1e-136 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
EKKJOAOI_00690 4.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
EKKJOAOI_00691 4.5e-43 gutM K Glucitol operon activator protein (GutM)
EKKJOAOI_00692 1.3e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
EKKJOAOI_00693 5.2e-110 IQ NAD dependent epimerase/dehydratase family
EKKJOAOI_00694 1.8e-162 ytbD EGP Major facilitator Superfamily
EKKJOAOI_00695 3e-98 fabK 1.3.1.9 S Nitronate monooxygenase
EKKJOAOI_00696 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EKKJOAOI_00698 1.1e-265 fbp 3.1.3.11 G phosphatase activity
EKKJOAOI_00699 1.4e-70 xerD L Phage integrase, N-terminal SAM-like domain
EKKJOAOI_00702 2e-86 mesE M Transport protein ComB
EKKJOAOI_00703 1.2e-281 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EKKJOAOI_00706 7.3e-56 K LytTr DNA-binding domain
EKKJOAOI_00707 1.8e-51 2.7.13.3 T GHKL domain
EKKJOAOI_00713 9.2e-16
EKKJOAOI_00715 7.2e-08
EKKJOAOI_00716 6.6e-19
EKKJOAOI_00717 5.9e-39 blpT
EKKJOAOI_00718 3e-87 S Haloacid dehalogenase-like hydrolase
EKKJOAOI_00719 1.8e-14
EKKJOAOI_00721 1.8e-28 S Phage gp6-like head-tail connector protein
EKKJOAOI_00722 3.1e-98
EKKJOAOI_00723 4e-08 S Domain of unknown function (DUF4355)
EKKJOAOI_00726 9.5e-17 S head morphogenesis protein, SPP1 gp7 family
EKKJOAOI_00727 5.9e-187 mtnE 2.6.1.83 E Aminotransferase
EKKJOAOI_00728 1.3e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
EKKJOAOI_00729 1.3e-66 S Protein of unknown function (DUF1440)
EKKJOAOI_00730 7.7e-41 S Iron-sulfur cluster assembly protein
EKKJOAOI_00731 3.3e-113 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
EKKJOAOI_00732 5.9e-75 sdaAB 4.3.1.17 E Serine dehydratase beta chain
EKKJOAOI_00733 5.1e-207 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EKKJOAOI_00734 5.6e-153 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EKKJOAOI_00735 4e-64 G Xylose isomerase domain protein TIM barrel
EKKJOAOI_00736 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
EKKJOAOI_00737 6.5e-90 nanK GK ROK family
EKKJOAOI_00738 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
EKKJOAOI_00739 2.5e-92 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EKKJOAOI_00740 4.3e-75 K Helix-turn-helix domain, rpiR family
EKKJOAOI_00741 1.5e-56 yphA GM NAD dependent epimerase/dehydratase family
EKKJOAOI_00742 6.9e-217 yjeM E Amino Acid
EKKJOAOI_00744 1.6e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EKKJOAOI_00745 3.4e-232 tetP J elongation factor G
EKKJOAOI_00747 1.3e-10 tcdC
EKKJOAOI_00749 7.3e-102 L PLD-like domain
EKKJOAOI_00750 4.1e-31 L Helix-turn-helix domain
EKKJOAOI_00751 3e-95 L Transposase IS66 family
EKKJOAOI_00754 3.9e-147 scrR K helix_turn _helix lactose operon repressor
EKKJOAOI_00755 5.9e-216 scrB 3.2.1.26 GH32 G invertase
EKKJOAOI_00756 1.4e-281 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
EKKJOAOI_00757 2.6e-183 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
EKKJOAOI_00758 1.2e-114 ntpJ P Potassium uptake protein
EKKJOAOI_00759 4.8e-58 ktrA P TrkA-N domain
EKKJOAOI_00760 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
EKKJOAOI_00761 1.3e-36 M Glycosyltransferase group 2 family protein
EKKJOAOI_00762 1.4e-19
EKKJOAOI_00763 1.8e-94 S Predicted membrane protein (DUF2207)
EKKJOAOI_00764 2.1e-54 bioY S BioY family
EKKJOAOI_00765 2.2e-94 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EKKJOAOI_00766 7.6e-74 glcR K DeoR C terminal sensor domain
EKKJOAOI_00767 2.2e-60 yceE S haloacid dehalogenase-like hydrolase
EKKJOAOI_00768 1.1e-41 S CAAX protease self-immunity
EKKJOAOI_00769 9.1e-34 S Domain of unknown function (DUF4811)
EKKJOAOI_00770 2.1e-197 lmrB EGP Major facilitator Superfamily
EKKJOAOI_00771 1.9e-32 merR K MerR HTH family regulatory protein
EKKJOAOI_00772 1.8e-39 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EKKJOAOI_00773 1.2e-70 S Protein of unknown function (DUF554)
EKKJOAOI_00774 2.8e-121 G Bacterial extracellular solute-binding protein
EKKJOAOI_00775 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
EKKJOAOI_00776 5.1e-99 baeS T Histidine kinase
EKKJOAOI_00777 1.1e-80 rbsB G sugar-binding domain protein
EKKJOAOI_00778 9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
EKKJOAOI_00779 6.4e-116 manY G PTS system sorbose-specific iic component
EKKJOAOI_00780 6.1e-147 manN G system, mannose fructose sorbose family IID component
EKKJOAOI_00781 2.4e-52 manO S Domain of unknown function (DUF956)
EKKJOAOI_00782 9.5e-16 S Protein of unknown function (DUF805)
EKKJOAOI_00783 2.1e-70 mltD CBM50 M NlpC P60 family protein
EKKJOAOI_00784 4.7e-130 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EKKJOAOI_00785 4.9e-165 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKKJOAOI_00786 2.4e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
EKKJOAOI_00787 3.5e-48 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EKKJOAOI_00788 5.6e-60 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EKKJOAOI_00789 1.1e-267 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EKKJOAOI_00790 3.9e-106 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EKKJOAOI_00791 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EKKJOAOI_00792 2e-46 S CRISPR-associated protein (Cas_Csn2)
EKKJOAOI_00794 6.4e-44 XK27_01125 L PFAM IS66 Orf2 family protein
EKKJOAOI_00795 1.6e-137 L Belongs to the 'phage' integrase family
EKKJOAOI_00796 8.1e-38 K transcriptional regulator PadR family
EKKJOAOI_00797 7.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
EKKJOAOI_00798 3.1e-16 S Putative adhesin
EKKJOAOI_00799 2.2e-16 pspC KT PspC domain
EKKJOAOI_00801 3e-13 S Enterocin A Immunity
EKKJOAOI_00802 5.2e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EKKJOAOI_00803 5.7e-261 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
EKKJOAOI_00804 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EKKJOAOI_00805 8.2e-167 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EKKJOAOI_00806 1.5e-120 potB P ABC transporter permease
EKKJOAOI_00807 1.7e-103 potC U Binding-protein-dependent transport system inner membrane component
EKKJOAOI_00808 1.3e-159 potD P ABC transporter
EKKJOAOI_00809 7.8e-132 ABC-SBP S ABC transporter
EKKJOAOI_00810 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
EKKJOAOI_00811 1.4e-107 XK27_08845 S ABC transporter, ATP-binding protein
EKKJOAOI_00812 1.5e-67 M ErfK YbiS YcfS YnhG
EKKJOAOI_00813 4.1e-54 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EKKJOAOI_00814 1.9e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EKKJOAOI_00815 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EKKJOAOI_00816 1.2e-102 pgm3 G phosphoglycerate mutase
EKKJOAOI_00817 8.5e-58 S CAAX protease self-immunity
EKKJOAOI_00818 2e-45 C Flavodoxin
EKKJOAOI_00819 1.2e-57 yphH S Cupin domain
EKKJOAOI_00820 1e-45 yphJ 4.1.1.44 S decarboxylase
EKKJOAOI_00821 1.2e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
EKKJOAOI_00822 5.1e-108 metQ1 P Belongs to the nlpA lipoprotein family
EKKJOAOI_00823 2e-149 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EKKJOAOI_00824 1.3e-69 metI P ABC transporter permease
EKKJOAOI_00825 8.8e-135 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
EKKJOAOI_00826 3e-84 drgA C nitroreductase
EKKJOAOI_00827 1.1e-83 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
EKKJOAOI_00828 1.7e-106 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
EKKJOAOI_00829 5.3e-171 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
EKKJOAOI_00830 1.7e-264 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
EKKJOAOI_00832 6.2e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EKKJOAOI_00833 2.4e-31 metI U ABC transporter permease
EKKJOAOI_00834 1.5e-128 metQ M Belongs to the nlpA lipoprotein family
EKKJOAOI_00835 6.5e-59 S Protein of unknown function (DUF4256)
EKKJOAOI_00838 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EKKJOAOI_00839 2.8e-166 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
EKKJOAOI_00840 1.5e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EKKJOAOI_00841 4e-230 lpdA 1.8.1.4 C Dehydrogenase
EKKJOAOI_00842 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
EKKJOAOI_00843 9.2e-56 S Protein of unknown function (DUF975)
EKKJOAOI_00844 2.2e-77 E GDSL-like Lipase/Acylhydrolase family
EKKJOAOI_00845 6.1e-39
EKKJOAOI_00846 4.1e-27 gcvR T Belongs to the UPF0237 family
EKKJOAOI_00847 2.1e-220 XK27_08635 S UPF0210 protein
EKKJOAOI_00848 4.5e-87 fruR K DeoR C terminal sensor domain
EKKJOAOI_00849 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EKKJOAOI_00850 5.1e-268 fruA 2.7.1.202 GT Phosphotransferase System
EKKJOAOI_00851 1.2e-49 cps3F
EKKJOAOI_00852 2.7e-83 S Membrane
EKKJOAOI_00853 1.8e-254 E Amino acid permease
EKKJOAOI_00854 5e-225 cadA P P-type ATPase
EKKJOAOI_00855 6.4e-114 degV S EDD domain protein, DegV family
EKKJOAOI_00856 1.9e-148 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
EKKJOAOI_00857 5.6e-57 yfeJ 6.3.5.2 F glutamine amidotransferase
EKKJOAOI_00858 1.9e-27 ydiI Q Thioesterase superfamily
EKKJOAOI_00859 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EKKJOAOI_00860 5.6e-139 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EKKJOAOI_00861 5.6e-82 S L,D-transpeptidase catalytic domain
EKKJOAOI_00862 4.4e-165 EGP Major facilitator Superfamily
EKKJOAOI_00863 1.1e-21 K helix_turn_helix multiple antibiotic resistance protein
EKKJOAOI_00864 6e-226 pipD E Dipeptidase
EKKJOAOI_00865 7e-126 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EKKJOAOI_00866 2.6e-32 ywjH S Protein of unknown function (DUF1634)
EKKJOAOI_00867 2.2e-119 yxaA S membrane transporter protein
EKKJOAOI_00868 7.6e-83 lysR5 K LysR substrate binding domain
EKKJOAOI_00869 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
EKKJOAOI_00870 9.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKKJOAOI_00871 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EKKJOAOI_00872 2.3e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
EKKJOAOI_00873 3.6e-242 lysP E amino acid
EKKJOAOI_00874 2.1e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EKKJOAOI_00875 7e-27 L PFAM transposase IS200-family protein
EKKJOAOI_00877 2e-271 helD 3.6.4.12 L DNA helicase
EKKJOAOI_00878 4.1e-73 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKKJOAOI_00879 1.3e-32 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EKKJOAOI_00880 6.7e-171 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
EKKJOAOI_00881 1.6e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EKKJOAOI_00882 4.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
EKKJOAOI_00883 5.9e-104 ybhR V ABC transporter
EKKJOAOI_00884 7.9e-32 K Bacterial regulatory proteins, tetR family
EKKJOAOI_00885 7.2e-43 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
EKKJOAOI_00886 3.3e-151 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EKKJOAOI_00887 3.9e-128
EKKJOAOI_00888 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EKKJOAOI_00889 7.8e-103 tatD L hydrolase, TatD family
EKKJOAOI_00890 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EKKJOAOI_00891 1.4e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EKKJOAOI_00892 2.7e-22 veg S Biofilm formation stimulator VEG
EKKJOAOI_00893 3.7e-90 S Alpha/beta hydrolase of unknown function (DUF915)
EKKJOAOI_00894 5.5e-134 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
EKKJOAOI_00895 8.2e-47 argR K Regulates arginine biosynthesis genes
EKKJOAOI_00896 4.8e-117 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EKKJOAOI_00897 3.5e-156 amtB P ammonium transporter
EKKJOAOI_00898 1.7e-201 argH 4.3.2.1 E argininosuccinate lyase
EKKJOAOI_00899 6.5e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EKKJOAOI_00900 1.5e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
EKKJOAOI_00901 9e-128 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKKJOAOI_00902 4.4e-101 pfoS S Phosphotransferase system, EIIC
EKKJOAOI_00903 3.9e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EKKJOAOI_00904 6.6e-53 adhR K helix_turn_helix, mercury resistance
EKKJOAOI_00905 5.2e-137 purR 2.4.2.7 F pur operon repressor
EKKJOAOI_00906 1.9e-47 EGP Transmembrane secretion effector
EKKJOAOI_00907 1.1e-192 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EKKJOAOI_00908 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EKKJOAOI_00909 3.1e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EKKJOAOI_00910 3.1e-113 dkg S reductase
EKKJOAOI_00911 1.7e-24
EKKJOAOI_00912 6.7e-78 2.4.2.3 F Phosphorylase superfamily
EKKJOAOI_00913 1.4e-290 ybiT S ABC transporter, ATP-binding protein
EKKJOAOI_00914 2.1e-18 ytkL S Beta-lactamase superfamily domain
EKKJOAOI_00915 1.2e-34 ytkL S Belongs to the UPF0173 family
EKKJOAOI_00916 4.5e-100 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EKKJOAOI_00917 2.1e-125 S overlaps another CDS with the same product name
EKKJOAOI_00918 2.2e-86 S overlaps another CDS with the same product name
EKKJOAOI_00920 4.6e-57 spoVK O ATPase family associated with various cellular activities (AAA)
EKKJOAOI_00921 2.3e-22
EKKJOAOI_00922 2.7e-38 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
EKKJOAOI_00924 1.3e-63
EKKJOAOI_00925 8.2e-216 L Probable transposase
EKKJOAOI_00926 6e-60 ydcZ S Putative inner membrane exporter, YdcZ
EKKJOAOI_00927 6.4e-87 S hydrolase
EKKJOAOI_00928 2.5e-205 ywfO S HD domain protein
EKKJOAOI_00929 9.8e-86 yfeJ 6.3.5.2 F glutamine amidotransferase
EKKJOAOI_00930 1.8e-32 ywiB S Domain of unknown function (DUF1934)
EKKJOAOI_00931 1e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EKKJOAOI_00932 1.2e-288 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EKKJOAOI_00935 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKKJOAOI_00936 1.2e-188 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EKKJOAOI_00937 3.6e-41 rpmE2 J Ribosomal protein L31
EKKJOAOI_00938 2.8e-61
EKKJOAOI_00939 7.8e-255 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
EKKJOAOI_00941 4.7e-79 S Cell surface protein
EKKJOAOI_00943 1.6e-180 pbuG S permease
EKKJOAOI_00944 8.4e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
EKKJOAOI_00945 1.8e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EKKJOAOI_00946 3.4e-208 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EKKJOAOI_00947 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EKKJOAOI_00948 4.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EKKJOAOI_00949 5.4e-13
EKKJOAOI_00950 3.4e-48 ndoA L Toxic component of a toxin-antitoxin (TA) module
EKKJOAOI_00951 2.5e-91 yunF F Protein of unknown function DUF72
EKKJOAOI_00952 2.3e-156 nrnB S DHHA1 domain
EKKJOAOI_00953 3.7e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EKKJOAOI_00954 2.2e-59
EKKJOAOI_00955 6e-49 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
EKKJOAOI_00956 5.4e-23 S Cytochrome B5
EKKJOAOI_00957 1.1e-19 sigH K DNA-templated transcription, initiation
EKKJOAOI_00958 2.9e-68 recX 2.4.1.337 GT4 S Regulatory protein RecX
EKKJOAOI_00959 3.2e-192 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EKKJOAOI_00960 2.6e-97 ygaC J Belongs to the UPF0374 family
EKKJOAOI_00961 6.9e-92 yueF S AI-2E family transporter
EKKJOAOI_00962 1.9e-157 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EKKJOAOI_00963 1.4e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EKKJOAOI_00964 4e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EKKJOAOI_00965 6.3e-36
EKKJOAOI_00966 0.0 lacL 3.2.1.23 G -beta-galactosidase
EKKJOAOI_00967 1.2e-288 lacS G Transporter
EKKJOAOI_00968 5.9e-111 galR K Transcriptional regulator
EKKJOAOI_00969 2.6e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EKKJOAOI_00970 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EKKJOAOI_00971 1.2e-200 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EKKJOAOI_00972 0.0 rafA 3.2.1.22 G alpha-galactosidase
EKKJOAOI_00973 5e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
EKKJOAOI_00974 3e-23 XK27_09445 S Domain of unknown function (DUF1827)
EKKJOAOI_00975 0.0 clpE O Belongs to the ClpA ClpB family
EKKJOAOI_00976 1.5e-15
EKKJOAOI_00977 9.7e-37 ptsH G phosphocarrier protein HPR
EKKJOAOI_00978 2.4e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EKKJOAOI_00979 3.9e-162 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EKKJOAOI_00980 1.2e-127 cpoA GT4 M Glycosyltransferase, group 1 family protein
EKKJOAOI_00981 1.5e-130 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKKJOAOI_00982 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
EKKJOAOI_00983 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EKKJOAOI_00988 2.1e-07
EKKJOAOI_00990 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EKKJOAOI_00991 2.1e-185 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EKKJOAOI_00992 6.3e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EKKJOAOI_00993 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EKKJOAOI_00994 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EKKJOAOI_00996 1.6e-55 ctsR K Belongs to the CtsR family
EKKJOAOI_00997 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EKKJOAOI_00998 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKKJOAOI_00999 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EKKJOAOI_01000 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
EKKJOAOI_01001 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EKKJOAOI_01002 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EKKJOAOI_01003 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EKKJOAOI_01004 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EKKJOAOI_01005 5.2e-90 patB 4.4.1.8 E Aminotransferase, class I
EKKJOAOI_01006 2.5e-113 K response regulator
EKKJOAOI_01007 3.3e-142 hpk31 2.7.13.3 T Histidine kinase
EKKJOAOI_01008 1.5e-91 lacX 5.1.3.3 G Aldose 1-epimerase
EKKJOAOI_01009 3.9e-146 G Transporter, major facilitator family protein
EKKJOAOI_01010 5.3e-224 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EKKJOAOI_01011 1.1e-244 yhcA V ABC transporter, ATP-binding protein
EKKJOAOI_01012 3.4e-35 K Bacterial regulatory proteins, tetR family
EKKJOAOI_01013 7.6e-223 lmrA V ABC transporter, ATP-binding protein
EKKJOAOI_01014 1.8e-254 yfiC V ABC transporter
EKKJOAOI_01016 3.2e-45 yjcF K protein acetylation
EKKJOAOI_01017 3.5e-26 S Sel1-like repeats.
EKKJOAOI_01018 5.4e-55 L phosphatase homologous to the C-terminal domain of histone macroH2A1
EKKJOAOI_01019 3.3e-71 lemA S LemA family
EKKJOAOI_01020 1.3e-114 htpX O Belongs to the peptidase M48B family
EKKJOAOI_01027 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EKKJOAOI_01028 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EKKJOAOI_01029 2.4e-192 cycA E Amino acid permease
EKKJOAOI_01030 2.4e-186 ytgP S Polysaccharide biosynthesis protein
EKKJOAOI_01031 2.8e-62 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EKKJOAOI_01032 1.1e-81 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EKKJOAOI_01033 8.7e-193 pepV 3.5.1.18 E dipeptidase PepV
EKKJOAOI_01034 6.3e-63 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
EKKJOAOI_01035 5.6e-67 L Type III restriction enzyme, res subunit
EKKJOAOI_01036 0.0 L Type III restriction enzyme, res subunit
EKKJOAOI_01038 4e-36
EKKJOAOI_01039 2.6e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EKKJOAOI_01040 4.2e-61 marR K Transcriptional regulator, MarR family
EKKJOAOI_01041 7.1e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKKJOAOI_01042 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKKJOAOI_01043 6.5e-104 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EKKJOAOI_01044 6.5e-99 IQ reductase
EKKJOAOI_01045 1.8e-194 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EKKJOAOI_01046 7.9e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EKKJOAOI_01047 1.5e-63 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EKKJOAOI_01048 9.3e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
EKKJOAOI_01049 2.7e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EKKJOAOI_01050 2.3e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
EKKJOAOI_01051 5.5e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EKKJOAOI_01052 2.8e-229 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EKKJOAOI_01053 3.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
EKKJOAOI_01054 4.6e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EKKJOAOI_01055 5.7e-119 gla U Major intrinsic protein
EKKJOAOI_01056 5.8e-45 ykuL S CBS domain
EKKJOAOI_01057 1.5e-60 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EKKJOAOI_01058 7.1e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EKKJOAOI_01059 1.5e-86 ykuT M mechanosensitive ion channel
EKKJOAOI_01061 5e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EKKJOAOI_01062 2e-21 yheA S Belongs to the UPF0342 family
EKKJOAOI_01063 5e-128 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
EKKJOAOI_01064 6.6e-114 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EKKJOAOI_01066 5.4e-53 hit FG histidine triad
EKKJOAOI_01067 1.3e-94 ecsA V ABC transporter, ATP-binding protein
EKKJOAOI_01068 1.4e-71 ecsB U ABC transporter
EKKJOAOI_01069 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
EKKJOAOI_01070 7.9e-101 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EKKJOAOI_01071 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EKKJOAOI_01072 2.3e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EKKJOAOI_01073 3.8e-238 sftA D Belongs to the FtsK SpoIIIE SftA family
EKKJOAOI_01074 7.6e-223 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EKKJOAOI_01075 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
EKKJOAOI_01076 6.7e-69 ybhL S Belongs to the BI1 family
EKKJOAOI_01077 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EKKJOAOI_01078 7.8e-57 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EKKJOAOI_01079 2.3e-36 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EKKJOAOI_01080 2.1e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EKKJOAOI_01081 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EKKJOAOI_01082 1.6e-79 dnaB L replication initiation and membrane attachment
EKKJOAOI_01083 2.2e-107 dnaI L Primosomal protein DnaI
EKKJOAOI_01084 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EKKJOAOI_01085 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EKKJOAOI_01086 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EKKJOAOI_01087 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EKKJOAOI_01088 2.5e-71 yqeG S HAD phosphatase, family IIIA
EKKJOAOI_01089 7.9e-181 yqeH S Ribosome biogenesis GTPase YqeH
EKKJOAOI_01090 1e-29 yhbY J RNA-binding protein
EKKJOAOI_01091 2.7e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EKKJOAOI_01092 7.2e-72 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
EKKJOAOI_01093 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EKKJOAOI_01094 5.5e-82 H Nodulation protein S (NodS)
EKKJOAOI_01095 1.3e-122 ylbM S Belongs to the UPF0348 family
EKKJOAOI_01096 3.9e-56 yceD S Uncharacterized ACR, COG1399
EKKJOAOI_01097 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EKKJOAOI_01098 1.2e-88 plsC 2.3.1.51 I Acyltransferase
EKKJOAOI_01099 8.5e-94 yabB 2.1.1.223 L Methyltransferase small domain
EKKJOAOI_01100 1.5e-27 yazA L GIY-YIG catalytic domain protein
EKKJOAOI_01101 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
EKKJOAOI_01102 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EKKJOAOI_01103 6.9e-37
EKKJOAOI_01104 3.4e-92 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
EKKJOAOI_01105 1.8e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EKKJOAOI_01106 2.7e-157 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EKKJOAOI_01107 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EKKJOAOI_01108 9.5e-106 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EKKJOAOI_01110 3.1e-111 K response regulator
EKKJOAOI_01111 5e-167 arlS 2.7.13.3 T Histidine kinase
EKKJOAOI_01112 1.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EKKJOAOI_01113 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EKKJOAOI_01114 1.6e-136 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
EKKJOAOI_01115 7.3e-105
EKKJOAOI_01116 7.2e-117
EKKJOAOI_01117 1.3e-41 dut S dUTPase
EKKJOAOI_01118 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EKKJOAOI_01119 3.7e-46 yqhY S Asp23 family, cell envelope-related function
EKKJOAOI_01120 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EKKJOAOI_01121 3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EKKJOAOI_01122 2e-146 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EKKJOAOI_01123 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EKKJOAOI_01124 1.4e-82 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EKKJOAOI_01125 2.9e-14 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EKKJOAOI_01126 1.5e-91 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EKKJOAOI_01127 1.5e-48 argR K Regulates arginine biosynthesis genes
EKKJOAOI_01128 2.7e-177 recN L May be involved in recombinational repair of damaged DNA
EKKJOAOI_01129 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EKKJOAOI_01130 2.2e-30 ynzC S UPF0291 protein
EKKJOAOI_01131 5.9e-27 yneF S UPF0154 protein
EKKJOAOI_01132 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
EKKJOAOI_01133 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
EKKJOAOI_01134 2.1e-74 yciQ P membrane protein (DUF2207)
EKKJOAOI_01135 3e-19 D nuclear chromosome segregation
EKKJOAOI_01136 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EKKJOAOI_01137 1.6e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EKKJOAOI_01138 7.4e-70 gluP 3.4.21.105 S Peptidase, S54 family
EKKJOAOI_01139 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
EKKJOAOI_01140 4.7e-158 glk 2.7.1.2 G Glucokinase
EKKJOAOI_01141 8e-46 yqhL P Rhodanese-like protein
EKKJOAOI_01142 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
EKKJOAOI_01143 1.9e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EKKJOAOI_01144 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
EKKJOAOI_01145 1.3e-45 glnR K Transcriptional regulator
EKKJOAOI_01146 2e-247 glnA 6.3.1.2 E glutamine synthetase
EKKJOAOI_01148 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EKKJOAOI_01149 2.7e-48 S Domain of unknown function (DUF956)
EKKJOAOI_01150 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EKKJOAOI_01151 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EKKJOAOI_01152 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EKKJOAOI_01153 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
EKKJOAOI_01154 4.1e-157 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EKKJOAOI_01155 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EKKJOAOI_01156 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKKJOAOI_01157 8e-66 rimP J Required for maturation of 30S ribosomal subunits
EKKJOAOI_01158 4.8e-170 nusA K Participates in both transcription termination and antitermination
EKKJOAOI_01159 1.4e-39 ylxR K Protein of unknown function (DUF448)
EKKJOAOI_01160 6.8e-26 ylxQ J ribosomal protein
EKKJOAOI_01161 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EKKJOAOI_01162 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EKKJOAOI_01163 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EKKJOAOI_01164 2.5e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EKKJOAOI_01165 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EKKJOAOI_01166 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EKKJOAOI_01167 1.5e-274 dnaK O Heat shock 70 kDa protein
EKKJOAOI_01168 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EKKJOAOI_01169 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EKKJOAOI_01171 9.2e-206 glnP P ABC transporter
EKKJOAOI_01172 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EKKJOAOI_01173 1.5e-31
EKKJOAOI_01174 2e-111 ampC V Beta-lactamase
EKKJOAOI_01175 3.5e-110 cobQ S glutamine amidotransferase
EKKJOAOI_01176 4.7e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
EKKJOAOI_01177 6.8e-86 tdk 2.7.1.21 F thymidine kinase
EKKJOAOI_01178 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EKKJOAOI_01179 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EKKJOAOI_01180 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EKKJOAOI_01181 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EKKJOAOI_01182 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
EKKJOAOI_01183 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKKJOAOI_01184 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EKKJOAOI_01185 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EKKJOAOI_01186 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EKKJOAOI_01187 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EKKJOAOI_01188 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EKKJOAOI_01189 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EKKJOAOI_01190 4.1e-15 ywzB S Protein of unknown function (DUF1146)
EKKJOAOI_01191 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EKKJOAOI_01192 3.4e-167 mbl D Cell shape determining protein MreB Mrl
EKKJOAOI_01193 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EKKJOAOI_01194 1.8e-12 S Protein of unknown function (DUF2969)
EKKJOAOI_01195 6.1e-187 rodA D Belongs to the SEDS family
EKKJOAOI_01196 7.9e-26 arsC 1.20.4.1 P Belongs to the ArsC family
EKKJOAOI_01197 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
EKKJOAOI_01198 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EKKJOAOI_01199 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EKKJOAOI_01200 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EKKJOAOI_01201 2.4e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EKKJOAOI_01202 5.8e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EKKJOAOI_01203 6.4e-153 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EKKJOAOI_01204 3.3e-90 stp 3.1.3.16 T phosphatase
EKKJOAOI_01205 3.4e-191 KLT serine threonine protein kinase
EKKJOAOI_01206 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EKKJOAOI_01207 3.8e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
EKKJOAOI_01208 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EKKJOAOI_01209 4.5e-53 asp S Asp23 family, cell envelope-related function
EKKJOAOI_01210 3.7e-238 yloV S DAK2 domain fusion protein YloV
EKKJOAOI_01211 3.3e-246 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EKKJOAOI_01212 2.1e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EKKJOAOI_01213 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EKKJOAOI_01214 2.5e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EKKJOAOI_01215 4.7e-211 smc D Required for chromosome condensation and partitioning
EKKJOAOI_01216 9.1e-149 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EKKJOAOI_01217 7e-40 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EKKJOAOI_01218 5e-204 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EKKJOAOI_01219 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EKKJOAOI_01220 1.1e-26 ylqC S Belongs to the UPF0109 family
EKKJOAOI_01221 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EKKJOAOI_01222 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EKKJOAOI_01223 5.7e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
EKKJOAOI_01224 3.5e-197 yfnA E amino acid
EKKJOAOI_01225 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EKKJOAOI_01226 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
EKKJOAOI_01227 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EKKJOAOI_01228 5.3e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EKKJOAOI_01229 3.8e-267 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKKJOAOI_01230 4e-18 S Tetratricopeptide repeat
EKKJOAOI_01231 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EKKJOAOI_01232 1.7e-195 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EKKJOAOI_01233 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EKKJOAOI_01234 2.3e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EKKJOAOI_01235 1.5e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EKKJOAOI_01236 5e-23 ykzG S Belongs to the UPF0356 family
EKKJOAOI_01237 1.6e-24
EKKJOAOI_01238 8.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EKKJOAOI_01239 3.7e-32 1.1.1.27 C L-malate dehydrogenase activity
EKKJOAOI_01240 1.7e-23 yktA S Belongs to the UPF0223 family
EKKJOAOI_01241 9.7e-77 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EKKJOAOI_01242 0.0 typA T GTP-binding protein TypA
EKKJOAOI_01243 6e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
EKKJOAOI_01244 1.6e-114 manY G PTS system
EKKJOAOI_01245 3.3e-148 manN G system, mannose fructose sorbose family IID component
EKKJOAOI_01246 1.6e-102 ftsW D Belongs to the SEDS family
EKKJOAOI_01247 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EKKJOAOI_01248 1.1e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
EKKJOAOI_01249 7.2e-74 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
EKKJOAOI_01250 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EKKJOAOI_01251 2.4e-131 ylbL T Belongs to the peptidase S16 family
EKKJOAOI_01252 2.2e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EKKJOAOI_01253 2.2e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKKJOAOI_01254 6.8e-103 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKKJOAOI_01255 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EKKJOAOI_01256 2.1e-226 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EKKJOAOI_01257 2.4e-139 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EKKJOAOI_01258 5.2e-75 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EKKJOAOI_01259 8.5e-234 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EKKJOAOI_01260 1e-152 purD 6.3.4.13 F Belongs to the GARS family
EKKJOAOI_01261 1.5e-93 S Acyltransferase family
EKKJOAOI_01262 2.2e-194 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EKKJOAOI_01263 3.9e-122 K LysR substrate binding domain
EKKJOAOI_01265 2.2e-20
EKKJOAOI_01266 6.2e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EKKJOAOI_01267 2.2e-267 argS 6.1.1.19 J Arginyl-tRNA synthetase
EKKJOAOI_01268 1.4e-50 comEA L Competence protein ComEA
EKKJOAOI_01269 2e-69 comEB 3.5.4.12 F ComE operon protein 2
EKKJOAOI_01270 3.3e-154 comEC S Competence protein ComEC
EKKJOAOI_01271 9.3e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
EKKJOAOI_01272 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EKKJOAOI_01273 3e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
EKKJOAOI_01274 2.8e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EKKJOAOI_01275 1.8e-93 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EKKJOAOI_01276 3.9e-229 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EKKJOAOI_01277 1.8e-36 ypmB S Protein conserved in bacteria
EKKJOAOI_01278 1.2e-142 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EKKJOAOI_01279 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
EKKJOAOI_01280 5.1e-56 dnaD L DnaD domain protein
EKKJOAOI_01281 4.4e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EKKJOAOI_01282 5.8e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EKKJOAOI_01283 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKKJOAOI_01284 1.9e-93 M transferase activity, transferring glycosyl groups
EKKJOAOI_01285 1.4e-83 M Glycosyltransferase sugar-binding region containing DXD motif
EKKJOAOI_01286 5.8e-100 epsJ1 M Glycosyltransferase like family 2
EKKJOAOI_01289 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EKKJOAOI_01290 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EKKJOAOI_01291 1.8e-56 yqeY S YqeY-like protein
EKKJOAOI_01293 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
EKKJOAOI_01294 1e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKKJOAOI_01295 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EKKJOAOI_01296 6.6e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EKKJOAOI_01297 2.9e-276 yfmR S ABC transporter, ATP-binding protein
EKKJOAOI_01298 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EKKJOAOI_01299 3.2e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EKKJOAOI_01300 8.6e-135 yvgN C Aldo keto reductase
EKKJOAOI_01301 2.4e-35 K helix_turn_helix, mercury resistance
EKKJOAOI_01302 1.3e-102 S Aldo keto reductase
EKKJOAOI_01304 6.5e-80 ypmR E GDSL-like Lipase/Acylhydrolase
EKKJOAOI_01305 2.2e-52 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
EKKJOAOI_01306 3.6e-24 yozE S Belongs to the UPF0346 family
EKKJOAOI_01307 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EKKJOAOI_01308 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EKKJOAOI_01309 6.2e-85 dprA LU DNA protecting protein DprA
EKKJOAOI_01310 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EKKJOAOI_01311 9.5e-210 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EKKJOAOI_01312 5.8e-205 G PTS system Galactitol-specific IIC component
EKKJOAOI_01313 2.3e-81 K Bacterial regulatory proteins, tetR family
EKKJOAOI_01314 1.6e-128 yjjC V ATPases associated with a variety of cellular activities
EKKJOAOI_01315 2.1e-203 M Exporter of polyketide antibiotics
EKKJOAOI_01316 1.8e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
EKKJOAOI_01317 2.7e-35 S Repeat protein
EKKJOAOI_01318 2e-277 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EKKJOAOI_01319 3.4e-91 L Belongs to the 'phage' integrase family
EKKJOAOI_01320 4.3e-14 L Belongs to the 'phage' integrase family
EKKJOAOI_01322 1.4e-22 dinG 2.7.7.7, 3.6.4.12 L DNA-directed DNA polymerase activity
EKKJOAOI_01323 1.9e-13
EKKJOAOI_01324 1.7e-17 L nuclease
EKKJOAOI_01325 9.6e-28 S Short C-terminal domain
EKKJOAOI_01327 8.4e-38 E Zn peptidase
EKKJOAOI_01328 2.4e-37 K Helix-turn-helix XRE-family like proteins
EKKJOAOI_01329 3.5e-10 XK27_07105 K Helix-turn-helix XRE-family like proteins
EKKJOAOI_01332 3.8e-86 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKKJOAOI_01333 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
EKKJOAOI_01334 9.1e-43 yodB K Transcriptional regulator, HxlR family
EKKJOAOI_01335 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EKKJOAOI_01336 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EKKJOAOI_01337 1.5e-126 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EKKJOAOI_01338 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
EKKJOAOI_01339 2.2e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EKKJOAOI_01340 6.4e-12
EKKJOAOI_01341 1.5e-143 iunH2 3.2.2.1 F nucleoside hydrolase
EKKJOAOI_01342 1.3e-42 XK27_03960 S Protein of unknown function (DUF3013)
EKKJOAOI_01343 1.9e-116 prmA J Ribosomal protein L11 methyltransferase
EKKJOAOI_01344 1.8e-77 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EKKJOAOI_01345 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EKKJOAOI_01346 1.7e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EKKJOAOI_01347 2.5e-56 3.1.3.18 J HAD-hyrolase-like
EKKJOAOI_01348 5.2e-43 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EKKJOAOI_01349 5.6e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EKKJOAOI_01350 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EKKJOAOI_01351 2.7e-204 pyrP F Permease
EKKJOAOI_01352 2.8e-114 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EKKJOAOI_01353 2.2e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EKKJOAOI_01354 2e-84 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EKKJOAOI_01355 2.3e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EKKJOAOI_01356 8.3e-134 K Transcriptional regulator
EKKJOAOI_01357 1.1e-143 ppaC 3.6.1.1 C inorganic pyrophosphatase
EKKJOAOI_01358 8.6e-115 glcR K DeoR C terminal sensor domain
EKKJOAOI_01359 4.5e-171 patA 2.6.1.1 E Aminotransferase
EKKJOAOI_01360 2.4e-88 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EKKJOAOI_01362 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EKKJOAOI_01363 6.1e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EKKJOAOI_01364 1.8e-36 rnhA 3.1.26.4 L Ribonuclease HI
EKKJOAOI_01365 6.2e-21 S Family of unknown function (DUF5322)
EKKJOAOI_01366 3.8e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EKKJOAOI_01367 8e-39
EKKJOAOI_01371 2.8e-16 V PFAM secretion protein HlyD family protein
EKKJOAOI_01373 8.7e-150 EGP Sugar (and other) transporter
EKKJOAOI_01374 6e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
EKKJOAOI_01375 5.7e-104 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EKKJOAOI_01376 6.5e-184 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EKKJOAOI_01377 4.2e-73 alkD L DNA alkylation repair enzyme
EKKJOAOI_01378 3.8e-136 EG EamA-like transporter family
EKKJOAOI_01379 3.6e-150 S Tetratricopeptide repeat protein
EKKJOAOI_01380 2.4e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
EKKJOAOI_01381 8.7e-299 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EKKJOAOI_01382 7e-127 corA P CorA-like Mg2+ transporter protein
EKKJOAOI_01383 8.5e-161 nhaC C Na H antiporter NhaC
EKKJOAOI_01384 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EKKJOAOI_01385 2.2e-80 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
EKKJOAOI_01387 4.2e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EKKJOAOI_01388 5.8e-155 iscS 2.8.1.7 E Aminotransferase class V
EKKJOAOI_01389 3.7e-41 XK27_04120 S Putative amino acid metabolism
EKKJOAOI_01390 3.7e-202 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EKKJOAOI_01391 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EKKJOAOI_01392 4.3e-15 S Protein of unknown function (DUF2929)
EKKJOAOI_01393 0.0 dnaE 2.7.7.7 L DNA polymerase
EKKJOAOI_01394 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EKKJOAOI_01395 6.3e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EKKJOAOI_01397 2.2e-39 ypaA S Protein of unknown function (DUF1304)
EKKJOAOI_01398 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EKKJOAOI_01399 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EKKJOAOI_01400 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EKKJOAOI_01401 1.6e-201 FbpA K Fibronectin-binding protein
EKKJOAOI_01402 3.1e-40 K Transcriptional regulator
EKKJOAOI_01403 6.3e-117 degV S EDD domain protein, DegV family
EKKJOAOI_01404 3e-70 lepB 3.4.21.89 U Signal peptidase, peptidase S26
EKKJOAOI_01405 2.4e-40 6.3.3.2 S ASCH
EKKJOAOI_01406 1.8e-175 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EKKJOAOI_01407 5.3e-81 yjjH S Calcineurin-like phosphoesterase
EKKJOAOI_01408 1.8e-95 EG EamA-like transporter family
EKKJOAOI_01409 2.5e-84 natB CP ABC-type Na efflux pump, permease component
EKKJOAOI_01410 4e-111 natA S Domain of unknown function (DUF4162)
EKKJOAOI_01411 6.2e-23 K Acetyltransferase (GNAT) domain
EKKJOAOI_01413 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EKKJOAOI_01414 2.2e-227 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EKKJOAOI_01415 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
EKKJOAOI_01416 1.3e-59 arsC 1.20.4.1 T Low molecular weight phosphatase family
EKKJOAOI_01417 2e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EKKJOAOI_01418 4.9e-29 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKKJOAOI_01419 1.4e-175 dltB M MBOAT, membrane-bound O-acyltransferase family
EKKJOAOI_01420 1.2e-219 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EKKJOAOI_01421 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
EKKJOAOI_01422 2e-90 recO L Involved in DNA repair and RecF pathway recombination
EKKJOAOI_01423 4.6e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EKKJOAOI_01424 2.8e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EKKJOAOI_01425 3e-60 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EKKJOAOI_01426 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
EKKJOAOI_01427 2.6e-83 lytH 3.5.1.28 M Ami_3
EKKJOAOI_01428 2.6e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EKKJOAOI_01429 7.7e-12 M Lysin motif
EKKJOAOI_01430 2.2e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
EKKJOAOI_01431 1.4e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
EKKJOAOI_01432 1.4e-220 mntH P H( )-stimulated, divalent metal cation uptake system
EKKJOAOI_01433 1.3e-44 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
EKKJOAOI_01434 3.2e-120 ica2 GT2 M Glycosyl transferase family group 2
EKKJOAOI_01435 1.4e-43
EKKJOAOI_01436 7.2e-92 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EKKJOAOI_01438 2.8e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EKKJOAOI_01439 3.4e-213 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EKKJOAOI_01440 2.8e-280 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EKKJOAOI_01441 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EKKJOAOI_01442 3.7e-109 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
EKKJOAOI_01443 3.1e-75 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EKKJOAOI_01444 9.5e-102 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
EKKJOAOI_01445 3.1e-77 hsdS_1 3.1.21.3 V K01154 type I restriction enzyme, S subunit
EKKJOAOI_01446 4.7e-131 L Belongs to the 'phage' integrase family
EKKJOAOI_01447 5.2e-69 3.1.21.3 V Type I restriction modification DNA specificity domain
EKKJOAOI_01448 4e-202 hsdM 2.1.1.72 V type I restriction-modification system
EKKJOAOI_01449 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
EKKJOAOI_01451 5.2e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
EKKJOAOI_01452 5.7e-57 3.6.1.27 I Acid phosphatase homologues
EKKJOAOI_01453 1.8e-68 maa 2.3.1.79 S Maltose acetyltransferase
EKKJOAOI_01454 4.8e-73 2.3.1.178 M GNAT acetyltransferase
EKKJOAOI_01456 1.4e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
EKKJOAOI_01457 3.5e-65 ypsA S Belongs to the UPF0398 family
EKKJOAOI_01458 6.4e-09 nhaC C Na H antiporter NhaC
EKKJOAOI_01459 2.9e-168 nhaC C Na H antiporter NhaC
EKKJOAOI_01460 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EKKJOAOI_01461 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
EKKJOAOI_01462 4.3e-113 xerD D recombinase XerD
EKKJOAOI_01463 2.4e-124 cvfB S S1 domain
EKKJOAOI_01464 4.1e-51 yeaL S Protein of unknown function (DUF441)
EKKJOAOI_01465 4.5e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EKKJOAOI_01466 5.8e-100 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EKKJOAOI_01467 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EKKJOAOI_01468 7e-59 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EKKJOAOI_01469 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EKKJOAOI_01470 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EKKJOAOI_01471 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EKKJOAOI_01472 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
EKKJOAOI_01473 4.5e-179 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
EKKJOAOI_01474 1.3e-99 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
EKKJOAOI_01476 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EKKJOAOI_01477 1e-27 ysxB J Cysteine protease Prp
EKKJOAOI_01478 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
EKKJOAOI_01481 2.9e-08 S Protein of unknown function (DUF2922)
EKKJOAOI_01483 1.3e-16 K DNA-templated transcription, initiation
EKKJOAOI_01485 1.1e-64 H Methyltransferase domain
EKKJOAOI_01486 1.7e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
EKKJOAOI_01487 1.3e-40 wecD M Acetyltransferase (GNAT) family
EKKJOAOI_01489 3.6e-26 ybl78 L Conserved phage C-terminus (Phg_2220_C)
EKKJOAOI_01490 1.3e-40 S Protein of unknown function (DUF1211)
EKKJOAOI_01491 5e-86 1.1.1.1 C Zinc-binding dehydrogenase
EKKJOAOI_01492 2.7e-30 S CHY zinc finger
EKKJOAOI_01493 2.1e-39 K Transcriptional regulator
EKKJOAOI_01494 3.4e-83 qorB 1.6.5.2 GM NmrA-like family
EKKJOAOI_01496 5.6e-126 M Glycosyl transferases group 1
EKKJOAOI_01497 3.4e-64 M Glycosyl transferases group 1
EKKJOAOI_01498 3.5e-166 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EKKJOAOI_01499 8e-146 lspL 5.1.3.6 GM RmlD substrate binding domain
EKKJOAOI_01500 1.4e-103 cps2I S Psort location CytoplasmicMembrane, score
EKKJOAOI_01501 2.3e-60 cps1B GT2,GT4 M Glycosyl transferases group 1
EKKJOAOI_01502 8e-117 S Glycosyltransferase WbsX
EKKJOAOI_01503 5.4e-53
EKKJOAOI_01505 9.7e-57 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
EKKJOAOI_01506 3.3e-41 GT2 S Glycosyltransferase, group 2 family protein
EKKJOAOI_01507 2.9e-74 M Glycosyltransferase Family 4
EKKJOAOI_01508 3.2e-76 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
EKKJOAOI_01509 3.6e-80 gtf1 2.4.1.52 GT4 M glycosyl transferase group 1
EKKJOAOI_01510 1.2e-120 2.4.1.52 GT4 M Glycosyl transferases group 1
EKKJOAOI_01511 2.2e-25 pglD 2.3.1.203 S Bacterial transferase hexapeptide (six repeats)
EKKJOAOI_01512 1.6e-77 epsL M Bacterial sugar transferase
EKKJOAOI_01513 2.8e-168 2.6.1.102 M Belongs to the DegT DnrJ EryC1 family
EKKJOAOI_01514 7.7e-218 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM CoA-binding domain
EKKJOAOI_01515 5.3e-48 cps4C M Chain length determinant protein
EKKJOAOI_01516 3e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
EKKJOAOI_01517 1.3e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EKKJOAOI_01518 8.1e-81
EKKJOAOI_01519 1.8e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
EKKJOAOI_01520 1e-113 yitU 3.1.3.104 S hydrolase
EKKJOAOI_01521 6.2e-59 speG J Acetyltransferase (GNAT) domain
EKKJOAOI_01522 2.6e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EKKJOAOI_01523 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EKKJOAOI_01524 5e-204 pipD E Dipeptidase
EKKJOAOI_01525 1.9e-44
EKKJOAOI_01526 1.6e-64 K helix_turn_helix, arabinose operon control protein
EKKJOAOI_01527 9.9e-53 S Membrane
EKKJOAOI_01528 0.0 rafA 3.2.1.22 G alpha-galactosidase
EKKJOAOI_01529 2.3e-59 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
EKKJOAOI_01530 2.2e-307 L Helicase C-terminal domain protein
EKKJOAOI_01531 1.1e-50 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
EKKJOAOI_01532 1.7e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
EKKJOAOI_01533 1.4e-113 2.7.7.65 T diguanylate cyclase activity
EKKJOAOI_01534 9.4e-222 ydaN S Bacterial cellulose synthase subunit
EKKJOAOI_01535 3.9e-75 ydaN S Bacterial cellulose synthase subunit
EKKJOAOI_01536 1.5e-201 ydaM M Glycosyl transferase family group 2
EKKJOAOI_01537 6.5e-205 S Protein conserved in bacteria
EKKJOAOI_01538 7.9e-181
EKKJOAOI_01539 3.6e-127 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
EKKJOAOI_01540 4.9e-32 2.7.7.65 T GGDEF domain
EKKJOAOI_01542 1.5e-146 pbuO_1 S Permease family
EKKJOAOI_01543 1.9e-156 ndh 1.6.99.3 C NADH dehydrogenase
EKKJOAOI_01544 2e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
EKKJOAOI_01545 2.4e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EKKJOAOI_01546 2.3e-219 cydD CO ABC transporter transmembrane region
EKKJOAOI_01547 2.7e-204 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EKKJOAOI_01548 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
EKKJOAOI_01549 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
EKKJOAOI_01550 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
EKKJOAOI_01551 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
EKKJOAOI_01552 5e-19 glpE P Rhodanese Homology Domain
EKKJOAOI_01553 4.2e-49 lytE M LysM domain protein
EKKJOAOI_01554 1.4e-92 T Calcineurin-like phosphoesterase superfamily domain
EKKJOAOI_01555 5.7e-85 2.7.7.12 C Domain of unknown function (DUF4931)
EKKJOAOI_01557 4.4e-74 draG O ADP-ribosylglycohydrolase
EKKJOAOI_01558 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EKKJOAOI_01559 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EKKJOAOI_01560 1.1e-61 divIVA D DivIVA domain protein
EKKJOAOI_01561 1.7e-81 ylmH S S4 domain protein
EKKJOAOI_01562 3e-19 yggT S YGGT family
EKKJOAOI_01563 5e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EKKJOAOI_01564 9.8e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EKKJOAOI_01565 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EKKJOAOI_01566 1.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EKKJOAOI_01567 1.2e-152 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EKKJOAOI_01568 3.2e-184 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EKKJOAOI_01569 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EKKJOAOI_01570 4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
EKKJOAOI_01571 2.5e-11 ftsL D cell division protein FtsL
EKKJOAOI_01572 8e-142 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EKKJOAOI_01573 1.5e-55 mraZ K Belongs to the MraZ family
EKKJOAOI_01574 2.2e-07 S Protein of unknown function (DUF3397)
EKKJOAOI_01575 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
EKKJOAOI_01577 9.8e-100 D Alpha beta
EKKJOAOI_01578 3.7e-109 aatB ET ABC transporter substrate-binding protein
EKKJOAOI_01579 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EKKJOAOI_01580 1.9e-94 glnP P ABC transporter permease
EKKJOAOI_01581 1.8e-126 minD D Belongs to the ParA family
EKKJOAOI_01582 8.3e-77 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EKKJOAOI_01583 1.5e-54 mreD M rod shape-determining protein MreD
EKKJOAOI_01584 2.1e-88 mreC M Involved in formation and maintenance of cell shape
EKKJOAOI_01585 3.6e-156 mreB D cell shape determining protein MreB
EKKJOAOI_01586 4.5e-21 K Cold shock
EKKJOAOI_01587 3.1e-79 radC L DNA repair protein
EKKJOAOI_01588 1.1e-136 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EKKJOAOI_01589 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EKKJOAOI_01590 1.9e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EKKJOAOI_01591 6.4e-162 iscS2 2.8.1.7 E Aminotransferase class V
EKKJOAOI_01592 1.3e-174 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EKKJOAOI_01593 7.1e-56 ytsP 1.8.4.14 T GAF domain-containing protein
EKKJOAOI_01594 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EKKJOAOI_01595 3.4e-24 yueI S Protein of unknown function (DUF1694)
EKKJOAOI_01596 5.1e-184 rarA L recombination factor protein RarA
EKKJOAOI_01598 3.2e-73 usp6 T universal stress protein
EKKJOAOI_01599 3.7e-54 tag 3.2.2.20 L glycosylase
EKKJOAOI_01600 7.7e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EKKJOAOI_01601 5.9e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EKKJOAOI_01603 3.3e-75 yviA S Protein of unknown function (DUF421)
EKKJOAOI_01604 1.8e-27 S Protein of unknown function (DUF3290)
EKKJOAOI_01605 2.3e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
EKKJOAOI_01606 1.2e-296 S membrane
EKKJOAOI_01607 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EKKJOAOI_01608 6.1e-58 recJ L Single-stranded-DNA-specific exonuclease RecJ
EKKJOAOI_01609 6.5e-100 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
EKKJOAOI_01610 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EKKJOAOI_01612 1.4e-16
EKKJOAOI_01613 2.1e-199 oatA I Acyltransferase
EKKJOAOI_01614 1.8e-213 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EKKJOAOI_01615 2.8e-305 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EKKJOAOI_01616 1.2e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EKKJOAOI_01619 5.1e-42 S Phosphoesterase
EKKJOAOI_01620 2.2e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EKKJOAOI_01621 1.1e-60 yslB S Protein of unknown function (DUF2507)
EKKJOAOI_01622 9.9e-41 trxA O Belongs to the thioredoxin family
EKKJOAOI_01623 3.9e-310 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EKKJOAOI_01624 7.5e-15 cvpA S Colicin V production protein
EKKJOAOI_01625 1.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EKKJOAOI_01626 1.9e-33 yrzB S Belongs to the UPF0473 family
EKKJOAOI_01627 1e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EKKJOAOI_01628 2.1e-36 yrzL S Belongs to the UPF0297 family
EKKJOAOI_01629 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EKKJOAOI_01630 3.9e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EKKJOAOI_01631 2.1e-121 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
EKKJOAOI_01632 7.5e-13
EKKJOAOI_01633 2.1e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EKKJOAOI_01634 3.2e-66 yrjD S LUD domain
EKKJOAOI_01635 2.1e-245 lutB C 4Fe-4S dicluster domain
EKKJOAOI_01636 6.9e-117 lutA C Cysteine-rich domain
EKKJOAOI_01637 2e-208 yfnA E Amino Acid
EKKJOAOI_01639 4.3e-61 uspA T universal stress protein
EKKJOAOI_01641 1.8e-12 yajC U Preprotein translocase
EKKJOAOI_01642 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EKKJOAOI_01643 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EKKJOAOI_01644 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EKKJOAOI_01645 7.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EKKJOAOI_01646 6e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EKKJOAOI_01647 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EKKJOAOI_01648 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
EKKJOAOI_01649 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EKKJOAOI_01650 4.3e-85 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EKKJOAOI_01651 2.9e-64 ymfM S Helix-turn-helix domain
EKKJOAOI_01652 8.4e-91 IQ Enoyl-(Acyl carrier protein) reductase
EKKJOAOI_01653 3.4e-52 ymfH S Peptidase M16
EKKJOAOI_01654 1.7e-91 ymfH S Peptidase M16
EKKJOAOI_01655 3.5e-108 ymfF S Peptidase M16 inactive domain protein
EKKJOAOI_01656 1.6e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
EKKJOAOI_01657 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EKKJOAOI_01658 1.7e-98 rrmA 2.1.1.187 H Methyltransferase
EKKJOAOI_01659 4.9e-61 ybaK J Aminoacyl-tRNA editing domain
EKKJOAOI_01660 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EKKJOAOI_01661 4.3e-169 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EKKJOAOI_01662 3.2e-21 cutC P Participates in the control of copper homeostasis
EKKJOAOI_01663 3.4e-130 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
EKKJOAOI_01664 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
EKKJOAOI_01665 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EKKJOAOI_01666 5.3e-68 ybbR S YbbR-like protein
EKKJOAOI_01667 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EKKJOAOI_01668 2.4e-71 S Protein of unknown function (DUF1361)
EKKJOAOI_01669 1.2e-115 murB 1.3.1.98 M Cell wall formation
EKKJOAOI_01670 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
EKKJOAOI_01671 2.5e-56 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
EKKJOAOI_01672 2e-143 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EKKJOAOI_01673 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EKKJOAOI_01674 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
EKKJOAOI_01675 9.1e-42 yxjI
EKKJOAOI_01676 9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EKKJOAOI_01677 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EKKJOAOI_01678 2.8e-19 secG U Preprotein translocase
EKKJOAOI_01679 7e-180 clcA P chloride
EKKJOAOI_01680 6.7e-146 lmrP E Major Facilitator Superfamily
EKKJOAOI_01681 1.8e-169 T PhoQ Sensor
EKKJOAOI_01682 5e-104 K response regulator
EKKJOAOI_01683 3.3e-119 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EKKJOAOI_01684 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EKKJOAOI_01685 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EKKJOAOI_01686 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EKKJOAOI_01687 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EKKJOAOI_01688 1.1e-136 cggR K Putative sugar-binding domain
EKKJOAOI_01690 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EKKJOAOI_01691 6.7e-149 whiA K May be required for sporulation
EKKJOAOI_01692 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EKKJOAOI_01693 7.5e-126 rapZ S Displays ATPase and GTPase activities
EKKJOAOI_01694 2.7e-36 ylbE GM NAD dependent epimerase dehydratase family protein
EKKJOAOI_01695 2.9e-32 ylbE GM NAD(P)H-binding
EKKJOAOI_01696 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EKKJOAOI_01697 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EKKJOAOI_01698 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EKKJOAOI_01699 3.9e-272 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EKKJOAOI_01700 1.9e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EKKJOAOI_01701 9.6e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EKKJOAOI_01702 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
EKKJOAOI_01703 3.2e-08 KT PspC domain protein
EKKJOAOI_01704 3.5e-85 phoR 2.7.13.3 T Histidine kinase
EKKJOAOI_01705 4.6e-86 K response regulator
EKKJOAOI_01706 4.1e-68 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
EKKJOAOI_01707 1.2e-162 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EKKJOAOI_01708 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EKKJOAOI_01709 1.7e-96 yeaN P Major Facilitator Superfamily
EKKJOAOI_01710 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EKKJOAOI_01711 1e-45 comFC S Competence protein
EKKJOAOI_01712 4.6e-127 comFA L Helicase C-terminal domain protein
EKKJOAOI_01713 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
EKKJOAOI_01714 2.1e-295 ydaO E amino acid
EKKJOAOI_01715 2.8e-268 aha1 P COG COG0474 Cation transport ATPase
EKKJOAOI_01716 3.7e-272 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EKKJOAOI_01717 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EKKJOAOI_01718 8.2e-34 S CAAX protease self-immunity
EKKJOAOI_01719 1.3e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EKKJOAOI_01720 1.9e-254 uup S ABC transporter, ATP-binding protein
EKKJOAOI_01721 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EKKJOAOI_01722 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
EKKJOAOI_01723 2.8e-70 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
EKKJOAOI_01724 1.6e-140 ansA 3.5.1.1 EJ Asparaginase
EKKJOAOI_01725 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
EKKJOAOI_01726 3.2e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EKKJOAOI_01727 1.4e-40 yabA L Involved in initiation control of chromosome replication
EKKJOAOI_01728 5.2e-83 holB 2.7.7.7 L DNA polymerase III
EKKJOAOI_01729 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EKKJOAOI_01730 9.2e-29 yaaL S Protein of unknown function (DUF2508)
EKKJOAOI_01731 2.2e-97 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EKKJOAOI_01732 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EKKJOAOI_01733 5.1e-211 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EKKJOAOI_01734 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EKKJOAOI_01735 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
EKKJOAOI_01736 3.5e-27 nrdH O Glutaredoxin
EKKJOAOI_01737 4.8e-45 nrdI F NrdI Flavodoxin like
EKKJOAOI_01738 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKKJOAOI_01739 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EKKJOAOI_01740 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EKKJOAOI_01741 1.4e-54
EKKJOAOI_01742 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EKKJOAOI_01743 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EKKJOAOI_01744 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EKKJOAOI_01745 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EKKJOAOI_01746 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
EKKJOAOI_01747 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EKKJOAOI_01748 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EKKJOAOI_01749 7e-71 yacP S YacP-like NYN domain
EKKJOAOI_01750 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EKKJOAOI_01751 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EKKJOAOI_01752 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EKKJOAOI_01753 2.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EKKJOAOI_01754 8.2e-154 yacL S domain protein
EKKJOAOI_01755 1e-222 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EKKJOAOI_01756 6.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
EKKJOAOI_01757 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
EKKJOAOI_01758 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
EKKJOAOI_01759 1e-33 S Enterocin A Immunity
EKKJOAOI_01760 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EKKJOAOI_01761 4.5e-129 mleP2 S Sodium Bile acid symporter family
EKKJOAOI_01762 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EKKJOAOI_01764 3e-43 ydcK S Belongs to the SprT family
EKKJOAOI_01765 4.4e-252 yhgF K Tex-like protein N-terminal domain protein
EKKJOAOI_01766 1e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EKKJOAOI_01767 3.3e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EKKJOAOI_01768 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EKKJOAOI_01769 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
EKKJOAOI_01770 1e-89 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EKKJOAOI_01772 1.1e-07
EKKJOAOI_01773 1.6e-197 dtpT U amino acid peptide transporter

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)