ORF_ID e_value Gene_name EC_number CAZy COGs Description
IHMCCOPL_00001 7.5e-162 S Tetratricopeptide repeat
IHMCCOPL_00002 3.6e-31 yaeR E COG0346 Lactoylglutathione lyase and related lyases
IHMCCOPL_00003 3.3e-159 ypuA S secreted protein
IHMCCOPL_00004 6.1e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
IHMCCOPL_00005 4.4e-45 rpmE2 J 50S ribosomal protein L31
IHMCCOPL_00006 1.5e-29 K Helix-turn-helix domain
IHMCCOPL_00007 1.4e-16
IHMCCOPL_00008 0.0 lacS G transporter
IHMCCOPL_00009 0.0 lacL 3.2.1.23 G -beta-galactosidase
IHMCCOPL_00010 9.8e-38 M domain, Protein
IHMCCOPL_00012 4.5e-74 tcyB_2 P ABC transporter (permease)
IHMCCOPL_00013 3.9e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHMCCOPL_00014 2.1e-225 2.7.13.3 T protein histidine kinase activity
IHMCCOPL_00015 2.4e-202 hpk9 2.7.13.3 T protein histidine kinase activity
IHMCCOPL_00016 1.5e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IHMCCOPL_00017 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IHMCCOPL_00018 1.1e-211 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IHMCCOPL_00019 1.8e-309 lpdA 1.8.1.4 C Dehydrogenase
IHMCCOPL_00020 0.0 3.5.1.28 NU amidase activity
IHMCCOPL_00021 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
IHMCCOPL_00023 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IHMCCOPL_00024 1.9e-145 ycdO P periplasmic lipoprotein involved in iron transport
IHMCCOPL_00025 1.5e-230 ycdB P peroxidase
IHMCCOPL_00026 1.5e-287 ywbL P COG0672 High-affinity Fe2 Pb2 permease
IHMCCOPL_00027 7.1e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IHMCCOPL_00028 3e-24 tatA U protein secretion
IHMCCOPL_00029 1.8e-212 msmX P Belongs to the ABC transporter superfamily
IHMCCOPL_00030 9.8e-152 malG P ABC transporter (Permease
IHMCCOPL_00031 4.4e-250 malF P ABC transporter (Permease
IHMCCOPL_00032 1.9e-228 malX G ABC transporter
IHMCCOPL_00033 2.1e-156 malR K Transcriptional regulator
IHMCCOPL_00034 2.8e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
IHMCCOPL_00035 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IHMCCOPL_00036 4.8e-37
IHMCCOPL_00037 5.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
IHMCCOPL_00038 1.2e-196
IHMCCOPL_00039 8.6e-174 dnaG 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IHMCCOPL_00040 2.4e-125 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IHMCCOPL_00041 1e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHMCCOPL_00042 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHMCCOPL_00043 3.2e-220 vicK 2.7.13.3 T Histidine kinase
IHMCCOPL_00044 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
IHMCCOPL_00045 1.5e-56 S Protein of unknown function (DUF454)
IHMCCOPL_00046 4.3e-225 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
IHMCCOPL_00047 7.8e-146 yidA S hydrolases of the HAD superfamily
IHMCCOPL_00048 5.8e-147 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
IHMCCOPL_00049 5.3e-68 ywiB S Domain of unknown function (DUF1934)
IHMCCOPL_00050 0.0 pacL 3.6.3.8 P cation transport ATPase
IHMCCOPL_00051 5.3e-133 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IHMCCOPL_00052 1.8e-153 yjjH S Calcineurin-like phosphoesterase
IHMCCOPL_00053 6.6e-204 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IHMCCOPL_00054 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IHMCCOPL_00055 3.2e-124 ftsE D cell division ATP-binding protein FtsE
IHMCCOPL_00056 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IHMCCOPL_00057 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
IHMCCOPL_00058 4e-175 yubA S permease
IHMCCOPL_00059 1.4e-223 G COG0457 FOG TPR repeat
IHMCCOPL_00060 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IHMCCOPL_00061 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IHMCCOPL_00062 1.4e-231 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IHMCCOPL_00063 8.6e-87 ebsA S Family of unknown function (DUF5322)
IHMCCOPL_00064 2.5e-17 M LysM domain
IHMCCOPL_00065 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IHMCCOPL_00066 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IHMCCOPL_00067 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IHMCCOPL_00068 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IHMCCOPL_00069 5e-84 XK27_03610 K Gnat family
IHMCCOPL_00070 1.2e-91 yybC
IHMCCOPL_00071 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IHMCCOPL_00072 1.5e-15 S Tetratricopeptide repeat
IHMCCOPL_00073 1.3e-146 L Integrase core domain
IHMCCOPL_00074 4.6e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
IHMCCOPL_00075 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHMCCOPL_00076 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IHMCCOPL_00077 3.3e-78 2.3.1.128 J Acetyltransferase GNAT Family
IHMCCOPL_00078 1e-254 noxE P NADH oxidase
IHMCCOPL_00079 1.1e-294 yfmM S abc transporter atp-binding protein
IHMCCOPL_00080 3.4e-81 XK27_01265 S ECF-type riboflavin transporter, S component
IHMCCOPL_00081 2.4e-145 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IHMCCOPL_00082 6.3e-85 S ECF-type riboflavin transporter, S component
IHMCCOPL_00084 7.9e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IHMCCOPL_00085 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
IHMCCOPL_00087 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHMCCOPL_00088 5.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHMCCOPL_00089 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IHMCCOPL_00090 1e-22 WQ51_00220 K Helix-turn-helix domain
IHMCCOPL_00091 1.4e-77 S Protein of unknown function (DUF3278)
IHMCCOPL_00093 9.6e-102 S CAAX amino terminal protease family protein
IHMCCOPL_00094 5.7e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHMCCOPL_00095 2e-202 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IHMCCOPL_00096 4.6e-08 S Domain of unknown function (DUF4651)
IHMCCOPL_00097 3.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IHMCCOPL_00099 1.1e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHMCCOPL_00100 4.7e-120 S CAAX protease self-immunity
IHMCCOPL_00101 1.9e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IHMCCOPL_00102 5.1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IHMCCOPL_00106 4.7e-154 rrmA 2.1.1.187 Q methyltransferase
IHMCCOPL_00107 6.1e-137 S HAD hydrolase, family IA, variant
IHMCCOPL_00108 7.6e-57 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IHMCCOPL_00109 7.4e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IHMCCOPL_00110 8.5e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IHMCCOPL_00111 1.3e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IHMCCOPL_00112 1.9e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IHMCCOPL_00113 3.1e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IHMCCOPL_00114 1.2e-89 XK27_08585 S Psort location CytoplasmicMembrane, score
IHMCCOPL_00115 2.6e-138 fnt P Formate nitrite transporter
IHMCCOPL_00116 1.1e-223 XK27_09615 C reductase
IHMCCOPL_00117 5.3e-107 XK27_09620 S FMN reductase (NADPH) activity
IHMCCOPL_00118 1.1e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IHMCCOPL_00119 3.2e-69 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
IHMCCOPL_00120 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IHMCCOPL_00121 7e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
IHMCCOPL_00122 3.5e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
IHMCCOPL_00123 1.2e-50 S Protein of unknown function (DUF3397)
IHMCCOPL_00124 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IHMCCOPL_00125 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IHMCCOPL_00126 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IHMCCOPL_00127 1.5e-272 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IHMCCOPL_00128 1.4e-229 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
IHMCCOPL_00129 1.2e-150 hpk9 2.7.13.3 T protein histidine kinase activity
IHMCCOPL_00130 4.6e-209 hpk9 2.7.13.3 T protein histidine kinase activity
IHMCCOPL_00131 2.3e-224 fasC 2.7.13.3 T protein histidine kinase activity
IHMCCOPL_00132 7.2e-130 fasA KT Response regulator of the LytR AlgR family
IHMCCOPL_00133 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IHMCCOPL_00134 3.3e-269 argH 4.3.2.1 E Argininosuccinate lyase
IHMCCOPL_00135 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IHMCCOPL_00136 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHMCCOPL_00137 7.9e-175 jag S RNA-binding protein
IHMCCOPL_00138 1.9e-104 K Transcriptional regulator
IHMCCOPL_00139 6.3e-102 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
IHMCCOPL_00140 3.4e-14 rpmH J Ribosomal protein L34
IHMCCOPL_00141 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IHMCCOPL_00142 0.0 M Pilin isopeptide linkage domain protein
IHMCCOPL_00144 1.2e-74 XK27_03180 T universal stress protein
IHMCCOPL_00145 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
IHMCCOPL_00146 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IHMCCOPL_00147 3.7e-99 pncA Q isochorismatase
IHMCCOPL_00148 2.6e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IHMCCOPL_00149 1.5e-217 M lipopolysaccharide 3-alpha-galactosyltransferase activity
IHMCCOPL_00150 3.7e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
IHMCCOPL_00151 7e-189 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IHMCCOPL_00152 4e-233 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IHMCCOPL_00153 2.6e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHMCCOPL_00154 4.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IHMCCOPL_00155 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHMCCOPL_00157 4.1e-283 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IHMCCOPL_00158 7.2e-31 S PQ loop repeat
IHMCCOPL_00159 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
IHMCCOPL_00160 8.5e-279 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
IHMCCOPL_00161 1.7e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
IHMCCOPL_00162 3.2e-57
IHMCCOPL_00163 1.8e-216 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHMCCOPL_00164 1.8e-63
IHMCCOPL_00165 1.2e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IHMCCOPL_00166 1.4e-98 yqeG S hydrolase of the HAD superfamily
IHMCCOPL_00167 4.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IHMCCOPL_00168 7.7e-49 yhbY J RNA-binding protein
IHMCCOPL_00169 1.3e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IHMCCOPL_00170 2.2e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IHMCCOPL_00171 3e-87 entB 3.5.1.19 Q Isochorismatase family
IHMCCOPL_00172 5e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IHMCCOPL_00173 2.9e-139 yqeM Q Methyltransferase domain protein
IHMCCOPL_00174 2.9e-196 ylbM S Belongs to the UPF0348 family
IHMCCOPL_00175 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
IHMCCOPL_00177 1.6e-103
IHMCCOPL_00181 1.1e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IHMCCOPL_00182 3.7e-131 ecsA V abc transporter atp-binding protein
IHMCCOPL_00183 2.4e-176 ecsB U Bacterial ABC transporter protein EcsB
IHMCCOPL_00184 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
IHMCCOPL_00185 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IHMCCOPL_00187 1.6e-213 ytfP S Flavoprotein
IHMCCOPL_00188 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IHMCCOPL_00189 2.3e-63
IHMCCOPL_00190 1.3e-63 XK27_02560 S cog cog2151
IHMCCOPL_00191 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
IHMCCOPL_00192 6.4e-105 dnaQ 2.7.7.7 L DNA polymerase III
IHMCCOPL_00193 1.4e-125 K transcriptional regulator, MerR family
IHMCCOPL_00194 0.0 V ABC transporter (Permease
IHMCCOPL_00195 1.9e-124 V abc transporter atp-binding protein
IHMCCOPL_00197 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IHMCCOPL_00198 4e-47
IHMCCOPL_00199 2.9e-45
IHMCCOPL_00200 5.8e-46
IHMCCOPL_00201 0.0 ctpE P E1-E2 ATPase
IHMCCOPL_00202 2e-58
IHMCCOPL_00203 4.4e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
IHMCCOPL_00204 2e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IHMCCOPL_00205 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
IHMCCOPL_00206 5.1e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IHMCCOPL_00207 7.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IHMCCOPL_00208 1.1e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
IHMCCOPL_00209 8.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IHMCCOPL_00210 6.6e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IHMCCOPL_00212 2.7e-163 EGP Major facilitator Superfamily
IHMCCOPL_00213 6.1e-73 copY K negative regulation of transcription, DNA-templated
IHMCCOPL_00214 0.0 copA 3.6.3.54 P P-type ATPase
IHMCCOPL_00215 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
IHMCCOPL_00216 6e-191 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IHMCCOPL_00217 1.1e-113 papP P ABC transporter (Permease
IHMCCOPL_00218 1.3e-106 P ABC transporter (Permease
IHMCCOPL_00219 5.2e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHMCCOPL_00220 3.3e-155 cjaA ET ABC transporter substrate-binding protein
IHMCCOPL_00221 1.6e-31 L Integrase core domain protein
IHMCCOPL_00222 6.9e-215 L Transposase IS116 IS110 IS902
IHMCCOPL_00223 1e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IHMCCOPL_00224 2.6e-186 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IHMCCOPL_00225 0.0 dnaE 2.7.7.7 L DNA polymerase
IHMCCOPL_00226 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IHMCCOPL_00227 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IHMCCOPL_00228 1.3e-36 ysdA L Membrane
IHMCCOPL_00229 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IHMCCOPL_00230 1.2e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IHMCCOPL_00231 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHMCCOPL_00232 6.2e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
IHMCCOPL_00234 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IHMCCOPL_00235 4.1e-93 ypmS S Protein conserved in bacteria
IHMCCOPL_00236 3.1e-156 ypmR E COG2755 Lysophospholipase L1 and related esterases
IHMCCOPL_00237 3.4e-144 DegV S DegV family
IHMCCOPL_00238 2.1e-302 recN L May be involved in recombinational repair of damaged DNA
IHMCCOPL_00239 8.3e-73 argR K Regulates arginine biosynthesis genes
IHMCCOPL_00240 1.6e-146 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IHMCCOPL_00241 1.3e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IHMCCOPL_00242 1.3e-28 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHMCCOPL_00243 1.1e-232 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHMCCOPL_00245 4.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IHMCCOPL_00246 1.3e-125 dnaD
IHMCCOPL_00247 1.1e-180 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IHMCCOPL_00248 3.8e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHMCCOPL_00249 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
IHMCCOPL_00250 1.2e-65 GnaT 2.5.1.16 K acetyltransferase
IHMCCOPL_00251 1.6e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IHMCCOPL_00252 1.2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IHMCCOPL_00253 8.4e-111 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IHMCCOPL_00254 2.1e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHMCCOPL_00255 3.8e-228 rodA D Belongs to the SEDS family
IHMCCOPL_00256 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IHMCCOPL_00257 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IHMCCOPL_00258 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IHMCCOPL_00259 1.2e-180 XK27_08075 M glycosyl transferase family 2
IHMCCOPL_00260 2.7e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
IHMCCOPL_00261 2.1e-44 P molecular chaperone
IHMCCOPL_00262 6.5e-78 P molecular chaperone
IHMCCOPL_00263 3.4e-94 XK27_05505 S Psort location CytoplasmicMembrane, score
IHMCCOPL_00264 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
IHMCCOPL_00265 3.2e-17 S Domain of unknown function (DUF4649)
IHMCCOPL_00266 4e-176 XK27_08835 S ABC transporter substrate binding protein
IHMCCOPL_00267 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
IHMCCOPL_00268 3.1e-136 XK27_08845 S abc transporter atp-binding protein
IHMCCOPL_00269 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHMCCOPL_00270 5e-150 estA CE1 S Esterase
IHMCCOPL_00271 1.4e-125 XK27_08875 O Zinc-dependent metalloprotease
IHMCCOPL_00272 2.2e-18 XK27_08880
IHMCCOPL_00273 1e-75 fld C Flavodoxin
IHMCCOPL_00274 1.3e-279 clcA P Chloride transporter, ClC family
IHMCCOPL_00275 2.8e-39 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
IHMCCOPL_00276 2.4e-207 XK27_05110 P Chloride transporter ClC family
IHMCCOPL_00277 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IHMCCOPL_00280 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
IHMCCOPL_00281 2.1e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IHMCCOPL_00282 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
IHMCCOPL_00283 5.4e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHMCCOPL_00284 5.1e-173 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IHMCCOPL_00285 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHMCCOPL_00286 6.3e-93 pat 2.3.1.183 M acetyltransferase
IHMCCOPL_00287 1.4e-292 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHMCCOPL_00288 3.5e-120 alkD L Dna alkylation repair
IHMCCOPL_00289 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHMCCOPL_00290 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHMCCOPL_00291 9.3e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IHMCCOPL_00292 0.0 smc D Required for chromosome condensation and partitioning
IHMCCOPL_00294 6e-109 cutC P Participates in the control of copper homeostasis
IHMCCOPL_00295 4.4e-128 S CAAX amino terminal protease family
IHMCCOPL_00296 4.9e-94 ypgQ F HD superfamily hydrolase
IHMCCOPL_00297 8.9e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
IHMCCOPL_00298 7.1e-150 yitS S EDD domain protein, DegV family
IHMCCOPL_00299 2.8e-205 yeaN P transporter
IHMCCOPL_00300 2.2e-142 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IHMCCOPL_00301 3.2e-228 S Protein of unknown function DUF262
IHMCCOPL_00302 1e-287 S Protein of unknown function DUF262
IHMCCOPL_00303 2.5e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHMCCOPL_00304 2e-97 mip S hydroperoxide reductase activity
IHMCCOPL_00305 8.5e-201 I acyl-CoA dehydrogenase
IHMCCOPL_00306 6.5e-152 ydiA P C4-dicarboxylate transporter malic acid transport
IHMCCOPL_00307 1.4e-246 msrR K Transcriptional regulator
IHMCCOPL_00308 5.1e-153 pheA 4.2.1.51 E Prephenate dehydratase
IHMCCOPL_00309 2.9e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IHMCCOPL_00310 1.2e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IHMCCOPL_00311 1.4e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IHMCCOPL_00312 4.2e-53 yheA S Belongs to the UPF0342 family
IHMCCOPL_00313 4.5e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IHMCCOPL_00314 6.4e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IHMCCOPL_00315 2.9e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IHMCCOPL_00316 4.5e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IHMCCOPL_00317 3.2e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IHMCCOPL_00318 5.4e-217 ywbD 2.1.1.191 J Methyltransferase
IHMCCOPL_00319 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IHMCCOPL_00320 1.2e-25 WQ51_00785
IHMCCOPL_00321 1.9e-176 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
IHMCCOPL_00322 7e-127 K response regulator
IHMCCOPL_00323 4.3e-220 S Fibronectin-binding repeat
IHMCCOPL_00324 6.4e-72 L Transposase
IHMCCOPL_00325 3.8e-138 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IHMCCOPL_00326 2.1e-168 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IHMCCOPL_00327 6.1e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IHMCCOPL_00328 1e-44 yktA S Belongs to the UPF0223 family
IHMCCOPL_00329 1.7e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IHMCCOPL_00330 1e-125 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IHMCCOPL_00331 1.4e-30 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IHMCCOPL_00332 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IHMCCOPL_00333 7.1e-113 phoU P Plays a role in the regulation of phosphate uptake
IHMCCOPL_00334 0.0 pepN 3.4.11.2 E aminopeptidase
IHMCCOPL_00335 1.7e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IHMCCOPL_00336 1.1e-272 K Probable Zinc-ribbon domain
IHMCCOPL_00337 1.5e-161 yjlA EG membrane
IHMCCOPL_00338 9e-79 3.4.21.89 S RDD family
IHMCCOPL_00340 7.6e-120 K sequence-specific DNA binding
IHMCCOPL_00341 4.2e-10 MU outer membrane autotransporter barrel domain protein
IHMCCOPL_00342 1.3e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
IHMCCOPL_00343 6.6e-142 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
IHMCCOPL_00345 7.9e-25
IHMCCOPL_00346 0.0 yjcE P NhaP-type Na H and K H antiporters
IHMCCOPL_00347 1.9e-07
IHMCCOPL_00348 3.8e-96 ytqB J (SAM)-dependent
IHMCCOPL_00349 3.5e-182 yhcC S radical SAM protein
IHMCCOPL_00350 3.2e-187 ylbL T Belongs to the peptidase S16 family
IHMCCOPL_00351 7.3e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IHMCCOPL_00352 4.2e-104 rsmD 2.1.1.171 L Methyltransferase
IHMCCOPL_00353 4.7e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IHMCCOPL_00354 5e-10 S Protein of unknown function (DUF4059)
IHMCCOPL_00355 3.6e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
IHMCCOPL_00356 1e-162 yxeN P ABC transporter (Permease
IHMCCOPL_00357 1.9e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IHMCCOPL_00358 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IHMCCOPL_00359 8e-35
IHMCCOPL_00360 1.6e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHMCCOPL_00361 0.0 pflB 2.3.1.54 C formate acetyltransferase'
IHMCCOPL_00362 3.3e-141 cah 4.2.1.1 P carbonic anhydrase
IHMCCOPL_00363 1.9e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHMCCOPL_00365 3.7e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
IHMCCOPL_00366 9.5e-138 cppA E CppA N-terminal
IHMCCOPL_00367 1.4e-94 V CAAX protease self-immunity
IHMCCOPL_00368 5.6e-150 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
IHMCCOPL_00369 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IHMCCOPL_00370 9.2e-44 spiA K sequence-specific DNA binding
IHMCCOPL_00377 0.0 mdlB V abc transporter atp-binding protein
IHMCCOPL_00378 0.0 mdlA V abc transporter atp-binding protein
IHMCCOPL_00381 2.2e-88 XK27_09885 V Glycopeptide antibiotics resistance protein
IHMCCOPL_00382 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IHMCCOPL_00383 4.8e-62 yutD J protein conserved in bacteria
IHMCCOPL_00384 1.4e-248 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IHMCCOPL_00386 1.1e-219 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IHMCCOPL_00387 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHMCCOPL_00388 0.0 ftsI 3.4.16.4 M penicillin-binding protein
IHMCCOPL_00389 4e-45 ftsL D cell division protein FtsL
IHMCCOPL_00390 3.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IHMCCOPL_00391 1.1e-88
IHMCCOPL_00394 4.5e-38 yhaI J Protein of unknown function (DUF805)
IHMCCOPL_00395 1.4e-60 yhaI J Protein of unknown function (DUF805)
IHMCCOPL_00396 5.4e-34 yhaI J Protein of unknown function (DUF805)
IHMCCOPL_00397 3e-58 yhaI J Membrane
IHMCCOPL_00398 1.6e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IHMCCOPL_00399 1.3e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IHMCCOPL_00400 3.2e-276 XK27_00765
IHMCCOPL_00401 1.5e-132 ecsA_2 V abc transporter atp-binding protein
IHMCCOPL_00402 1.4e-125 S Protein of unknown function (DUF554)
IHMCCOPL_00403 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IHMCCOPL_00404 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IHMCCOPL_00405 6.2e-244 2.7.13.3 T protein histidine kinase activity
IHMCCOPL_00406 2.7e-233 dcuS 2.7.13.3 T protein histidine kinase activity
IHMCCOPL_00407 4e-14
IHMCCOPL_00410 5.8e-146 V Psort location CytoplasmicMembrane, score
IHMCCOPL_00412 1.7e-298 O MreB/Mbl protein
IHMCCOPL_00413 1.8e-119 liaI S membrane
IHMCCOPL_00414 2.6e-74 XK27_02470 K LytTr DNA-binding domain protein
IHMCCOPL_00415 0.0 KT response to antibiotic
IHMCCOPL_00416 6.3e-99 yebC M Membrane
IHMCCOPL_00417 6.8e-259 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
IHMCCOPL_00418 6e-177 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IHMCCOPL_00420 2.4e-30 yozG K Transcriptional regulator
IHMCCOPL_00424 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IHMCCOPL_00425 5.4e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHMCCOPL_00426 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IHMCCOPL_00427 8e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IHMCCOPL_00428 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IHMCCOPL_00429 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IHMCCOPL_00431 1.1e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
IHMCCOPL_00432 6.5e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
IHMCCOPL_00433 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IHMCCOPL_00434 5.6e-288 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
IHMCCOPL_00435 9.2e-178 scrR K Transcriptional regulator
IHMCCOPL_00436 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHMCCOPL_00437 1.7e-61 yqhY S protein conserved in bacteria
IHMCCOPL_00438 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHMCCOPL_00439 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
IHMCCOPL_00440 5.4e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
IHMCCOPL_00442 6.7e-145 V 'abc transporter, ATP-binding protein
IHMCCOPL_00443 2.8e-32 blpT
IHMCCOPL_00447 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IHMCCOPL_00448 5.6e-167 corA P COG0598 Mg2 and Co2 transporters
IHMCCOPL_00449 5e-122 XK27_01040 S Protein of unknown function (DUF1129)
IHMCCOPL_00451 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IHMCCOPL_00452 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IHMCCOPL_00453 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
IHMCCOPL_00454 2.7e-41 XK27_05745
IHMCCOPL_00455 2.7e-224 mutY L A G-specific adenine glycosylase
IHMCCOPL_00457 7.6e-10
IHMCCOPL_00458 1.3e-37
IHMCCOPL_00460 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHMCCOPL_00461 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IHMCCOPL_00462 6.1e-94 cvpA S toxin biosynthetic process
IHMCCOPL_00463 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IHMCCOPL_00464 1.2e-155 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHMCCOPL_00465 7.4e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IHMCCOPL_00466 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IHMCCOPL_00467 1.3e-46 azlD S branched-chain amino acid
IHMCCOPL_00468 1.5e-113 azlC E AzlC protein
IHMCCOPL_00469 9.6e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IHMCCOPL_00470 2.6e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IHMCCOPL_00471 3.9e-114 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
IHMCCOPL_00472 4.3e-33 ykzG S Belongs to the UPF0356 family
IHMCCOPL_00473 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHMCCOPL_00474 3.6e-114 pscB M CHAP domain protein
IHMCCOPL_00475 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
IHMCCOPL_00476 2.5e-62 glnR K Transcriptional regulator
IHMCCOPL_00477 3e-87 S Fusaric acid resistance protein-like
IHMCCOPL_00478 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IHMCCOPL_00479 1.1e-124
IHMCCOPL_00480 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
IHMCCOPL_00481 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IHMCCOPL_00482 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IHMCCOPL_00483 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IHMCCOPL_00484 4e-142 purR 2.4.2.7 F operon repressor
IHMCCOPL_00485 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
IHMCCOPL_00486 2.5e-170 rmuC S RmuC domain protein
IHMCCOPL_00487 1.8e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
IHMCCOPL_00488 3.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IHMCCOPL_00489 3.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IHMCCOPL_00491 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IHMCCOPL_00492 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IHMCCOPL_00493 1.6e-143 tatD L Hydrolase, tatd
IHMCCOPL_00494 1.2e-73 yccU S CoA-binding protein
IHMCCOPL_00495 2.4e-50 trxA O Belongs to the thioredoxin family
IHMCCOPL_00496 1.7e-142 S Macro domain protein
IHMCCOPL_00497 1.8e-61 L thioesterase
IHMCCOPL_00498 7.2e-53 bta 1.8.1.8 CO cell redox homeostasis
IHMCCOPL_00500 1.9e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
IHMCCOPL_00501 7.8e-149 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IHMCCOPL_00502 4.5e-142 K sequence-specific DNA binding
IHMCCOPL_00503 1.3e-85
IHMCCOPL_00504 3e-78 yfiQ K Acetyltransferase (GNAT) domain
IHMCCOPL_00505 9.6e-141 S ABC-2 family transporter protein
IHMCCOPL_00506 1.5e-141 S ABC transporter (permease)
IHMCCOPL_00507 3.2e-186 S abc transporter atp-binding protein
IHMCCOPL_00508 1.3e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHMCCOPL_00509 1.4e-190 desK 2.7.13.3 T Histidine kinase
IHMCCOPL_00510 1.5e-132 yvfS V ABC-2 type transporter
IHMCCOPL_00511 8.2e-157 XK27_09825 V 'abc transporter, ATP-binding protein
IHMCCOPL_00514 8.7e-165 yocS S Transporter
IHMCCOPL_00515 5.2e-83 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
IHMCCOPL_00516 1.6e-113 yvfS V Transporter
IHMCCOPL_00517 2.6e-155 XK27_09825 V abc transporter atp-binding protein
IHMCCOPL_00518 1.6e-14 liaI KT membrane
IHMCCOPL_00519 7.6e-30 liaI KT membrane
IHMCCOPL_00520 1e-92 XK27_05000 S metal cluster binding
IHMCCOPL_00521 0.0 V ABC transporter (permease)
IHMCCOPL_00522 1.6e-132 macB2 V ABC transporter, ATP-binding protein
IHMCCOPL_00523 1.4e-152 T Histidine kinase
IHMCCOPL_00524 2.7e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHMCCOPL_00525 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IHMCCOPL_00526 1.3e-216 pbuX F xanthine permease
IHMCCOPL_00527 2.2e-59 pdxH S pyridoxamine 5'-phosphate oxidase
IHMCCOPL_00528 1e-243 norM V Multidrug efflux pump
IHMCCOPL_00530 7.2e-183 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHMCCOPL_00531 5.4e-39 S SMI1-KNR4 cell-wall
IHMCCOPL_00532 2.5e-45 U A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IHMCCOPL_00533 0.0 S Domain of unknown function DUF87
IHMCCOPL_00534 4.4e-123 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IHMCCOPL_00535 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
IHMCCOPL_00536 3.9e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
IHMCCOPL_00537 1.8e-59 S Protein of unknown function (DUF3290)
IHMCCOPL_00538 3.4e-104 S Protein of unknown function (DUF421)
IHMCCOPL_00539 1.1e-16 csbD S CsbD-like
IHMCCOPL_00540 9.9e-110 S Carbohydrate-binding domain-containing protein Cthe_2159
IHMCCOPL_00541 2.3e-51 XK27_01300 S ASCH
IHMCCOPL_00542 2.1e-215 yfnA E amino acid
IHMCCOPL_00543 0.0 S dextransucrase activity
IHMCCOPL_00544 1.4e-57 M Putative cell wall binding repeat
IHMCCOPL_00546 4e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
IHMCCOPL_00547 6.2e-112 yxeN P ABC transporter, permease protein
IHMCCOPL_00548 1.6e-110 ytmL P ABC transporter (Permease
IHMCCOPL_00549 4.7e-165 ET ABC transporter substrate-binding protein
IHMCCOPL_00550 5.8e-175 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
IHMCCOPL_00551 4.3e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IHMCCOPL_00552 2e-42 S Sugar efflux transporter for intercellular exchange
IHMCCOPL_00553 3.4e-203 P FtsX-like permease family
IHMCCOPL_00554 3.9e-122 V abc transporter atp-binding protein
IHMCCOPL_00555 2.1e-97 K WHG domain
IHMCCOPL_00556 4e-170 ydhF S Aldo keto reductase
IHMCCOPL_00557 1.4e-06 S Protein of unknown function (DUF3169)
IHMCCOPL_00558 5.5e-27 XK27_07105 K transcriptional
IHMCCOPL_00559 8.8e-37
IHMCCOPL_00560 1.1e-109 XK27_02070 S nitroreductase
IHMCCOPL_00561 4.2e-150 1.13.11.2 S glyoxalase
IHMCCOPL_00562 1.1e-75 ywnA K Transcriptional regulator
IHMCCOPL_00563 2.6e-155 E Alpha/beta hydrolase of unknown function (DUF915)
IHMCCOPL_00564 1.5e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHMCCOPL_00565 1.8e-167 bcrA V abc transporter atp-binding protein
IHMCCOPL_00566 1.8e-128 S ABC-2 family transporter protein
IHMCCOPL_00567 1.4e-107 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IHMCCOPL_00568 1.1e-81 ypmB S Protein conserved in bacteria
IHMCCOPL_00569 4.5e-211 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IHMCCOPL_00570 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IHMCCOPL_00571 3.7e-19
IHMCCOPL_00572 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
IHMCCOPL_00573 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IHMCCOPL_00574 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
IHMCCOPL_00575 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IHMCCOPL_00576 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IHMCCOPL_00577 4e-204 D nuclear chromosome segregation
IHMCCOPL_00578 2.6e-135 yejC S cyclic nucleotide-binding protein
IHMCCOPL_00579 1e-162 rapZ S Displays ATPase and GTPase activities
IHMCCOPL_00580 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IHMCCOPL_00581 2.2e-160 whiA K May be required for sporulation
IHMCCOPL_00582 1.8e-275 pepD E Dipeptidase
IHMCCOPL_00583 6.9e-142 XK27_10720 D peptidase activity
IHMCCOPL_00584 2.9e-282 adcA P Belongs to the bacterial solute-binding protein 9 family
IHMCCOPL_00585 2.6e-09
IHMCCOPL_00587 2.6e-159 yeiH S Membrane
IHMCCOPL_00588 1e-125 mur1 3.4.17.14, 3.5.1.28 NU muramidase
IHMCCOPL_00589 2.9e-165 cpsY K Transcriptional regulator
IHMCCOPL_00590 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IHMCCOPL_00591 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
IHMCCOPL_00592 3.1e-105 artQ P ABC transporter (Permease
IHMCCOPL_00593 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHMCCOPL_00594 4.6e-157 aatB ET ABC transporter substrate-binding protein
IHMCCOPL_00595 5.7e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHMCCOPL_00596 7.5e-51
IHMCCOPL_00597 1.2e-45
IHMCCOPL_00598 5.1e-187 adhP 1.1.1.1 C alcohol dehydrogenase
IHMCCOPL_00599 1.5e-165 S CRISPR-associated protein Csn2 subfamily St
IHMCCOPL_00600 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHMCCOPL_00601 1.1e-169 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHMCCOPL_00602 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IHMCCOPL_00603 1.4e-287 sulP P Sulfate permease and related transporters (MFS superfamily)
IHMCCOPL_00604 7.3e-104
IHMCCOPL_00605 6.7e-116 estA E GDSL-like Lipase/Acylhydrolase
IHMCCOPL_00606 1.3e-92 S CAAX protease self-immunity
IHMCCOPL_00607 8.5e-52
IHMCCOPL_00609 1.8e-65 yqeB S Pyrimidine dimer DNA glycosylase
IHMCCOPL_00610 1.9e-60 S Protein of unknown function (DUF1722)
IHMCCOPL_00611 5.3e-21 S Bacterial lipoprotein
IHMCCOPL_00612 1.5e-10
IHMCCOPL_00613 5.2e-120 V CAAX protease self-immunity
IHMCCOPL_00614 4.6e-46
IHMCCOPL_00615 3.6e-76 K TetR family transcriptional regulator
IHMCCOPL_00616 2.4e-83 Q Methyltransferase domain
IHMCCOPL_00617 4.7e-142 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IHMCCOPL_00618 4.6e-175 acoB C dehydrogenase E1 component
IHMCCOPL_00619 2.4e-166 acoA C Acetoin dehydrogenase E1 component subunit alpha
IHMCCOPL_00620 5e-174 pdhD 1.8.1.4 C Dehydrogenase
IHMCCOPL_00621 2.9e-09 S CsbD-like
IHMCCOPL_00622 5.5e-31 S Membrane
IHMCCOPL_00623 6.1e-172 S Domain of unknown function (DUF389)
IHMCCOPL_00624 1.3e-157 yegS 2.7.1.107 I Diacylglycerol kinase
IHMCCOPL_00625 3.4e-126 ybbA S Putative esterase
IHMCCOPL_00626 4.7e-172 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IHMCCOPL_00627 3.7e-134 fecE 3.6.3.34 HP ABC transporter
IHMCCOPL_00628 2.3e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHMCCOPL_00629 6.6e-123 V CAAX protease self-immunity
IHMCCOPL_00630 5.8e-152 S Domain of unknown function (DUF4300)
IHMCCOPL_00631 9.2e-21 S Domain of unknown function (DUF4767)
IHMCCOPL_00632 3e-33 L COG1943 Transposase and inactivated derivatives
IHMCCOPL_00633 1.4e-129 T PhoQ Sensor
IHMCCOPL_00634 4.3e-121 T Transcriptional regulatory protein, C terminal
IHMCCOPL_00635 7.8e-109 drgA C nitroreductase
IHMCCOPL_00636 4.3e-113 yoaK S Protein of unknown function (DUF1275)
IHMCCOPL_00637 5.3e-40 DJ nuclease activity
IHMCCOPL_00638 1.9e-30 XK27_10490
IHMCCOPL_00639 4.6e-157 yvgN C reductase
IHMCCOPL_00640 3.2e-209 S Tetratricopeptide repeat
IHMCCOPL_00641 1.1e-146 M Glycosyltransferase like family 2
IHMCCOPL_00642 7e-124 cps3F
IHMCCOPL_00643 1.2e-245 epsU S Polysaccharide biosynthesis protein
IHMCCOPL_00644 2.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
IHMCCOPL_00645 2.5e-186 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
IHMCCOPL_00646 7.2e-176 wbbI M transferase activity, transferring glycosyl groups
IHMCCOPL_00648 1.5e-149 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IHMCCOPL_00649 1.4e-107 pgm G Belongs to the phosphoglycerate mutase family
IHMCCOPL_00650 4.1e-107 G Belongs to the phosphoglycerate mutase family
IHMCCOPL_00651 2.8e-108 G Belongs to the phosphoglycerate mutase family
IHMCCOPL_00652 1.4e-196 S hmm pf01594
IHMCCOPL_00653 2e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IHMCCOPL_00654 4.9e-39 S granule-associated protein
IHMCCOPL_00655 5.2e-287 S unusual protein kinase
IHMCCOPL_00656 4.8e-103 estA E Lysophospholipase L1 and related esterases
IHMCCOPL_00657 8.7e-156 rssA S Phospholipase, patatin family
IHMCCOPL_00658 3.8e-182 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
IHMCCOPL_00659 9.6e-250 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
IHMCCOPL_00660 2.8e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHMCCOPL_00661 1.2e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IHMCCOPL_00662 8.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IHMCCOPL_00663 0.0 S the current gene model (or a revised gene model) may contain a frame shift
IHMCCOPL_00664 1.2e-07 S Enterocin A Immunity
IHMCCOPL_00665 0.0 pepO 3.4.24.71 O Peptidase family M13
IHMCCOPL_00666 9.2e-34 S Immunity protein 41
IHMCCOPL_00667 0.0 M Putative cell wall binding repeat
IHMCCOPL_00668 4.5e-225 thrE K Psort location CytoplasmicMembrane, score
IHMCCOPL_00669 3.6e-177 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
IHMCCOPL_00670 5.8e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
IHMCCOPL_00671 1.1e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
IHMCCOPL_00672 1e-176 XK27_10475 S oxidoreductase
IHMCCOPL_00673 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
IHMCCOPL_00675 5e-284 XK27_07020 S Belongs to the UPF0371 family
IHMCCOPL_00676 2.6e-212 vex1 V Efflux ABC transporter, permease protein
IHMCCOPL_00677 1.9e-107 vex2 V abc transporter atp-binding protein
IHMCCOPL_00678 3.9e-238 vex3 V Efflux ABC transporter, permease protein
IHMCCOPL_00679 1.2e-115 K Response regulator receiver domain protein
IHMCCOPL_00680 2.7e-217 vncS 2.7.13.3 T Histidine kinase
IHMCCOPL_00681 5.1e-306 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
IHMCCOPL_00682 4.6e-151 galR K Transcriptional regulator
IHMCCOPL_00683 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IHMCCOPL_00684 6.8e-284 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IHMCCOPL_00685 6.2e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IHMCCOPL_00686 3.9e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IHMCCOPL_00687 9.9e-149 ycgQ S TIGR03943 family
IHMCCOPL_00688 3.2e-156 XK27_03015 S permease
IHMCCOPL_00690 0.0 yhgF K Transcriptional accessory protein
IHMCCOPL_00691 1e-83 ydcK S Belongs to the SprT family
IHMCCOPL_00692 2.2e-41 pspC KT PspC domain
IHMCCOPL_00693 2e-166 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IHMCCOPL_00694 9.9e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IHMCCOPL_00695 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IHMCCOPL_00696 3e-67 ytxH S General stress protein
IHMCCOPL_00698 1.5e-177 yegQ O Peptidase U32
IHMCCOPL_00699 1.9e-250 yegQ O Peptidase U32
IHMCCOPL_00700 3.9e-85 bioY S biotin synthase
IHMCCOPL_00702 1.1e-33 XK27_12190 S protein conserved in bacteria
IHMCCOPL_00703 2.8e-233 mntH P H( )-stimulated, divalent metal cation uptake system
IHMCCOPL_00704 1.5e-12
IHMCCOPL_00705 9.5e-65 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
IHMCCOPL_00706 0.0 L helicase
IHMCCOPL_00707 7e-97 K MerR, DNA binding
IHMCCOPL_00708 2.3e-179 dapB 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
IHMCCOPL_00709 2.8e-14
IHMCCOPL_00710 1.6e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IHMCCOPL_00711 1.3e-137 M LysM domain
IHMCCOPL_00712 8.4e-23
IHMCCOPL_00713 4.1e-175 S hydrolase
IHMCCOPL_00715 7.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
IHMCCOPL_00716 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IHMCCOPL_00717 3.5e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
IHMCCOPL_00718 7e-27 P Hemerythrin HHE cation binding domain protein
IHMCCOPL_00719 8.4e-159 5.2.1.8 G hydrolase
IHMCCOPL_00720 3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHMCCOPL_00721 6.8e-212 MA20_36090 S Protein of unknown function (DUF2974)
IHMCCOPL_00722 6.7e-131 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IHMCCOPL_00723 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IHMCCOPL_00724 7.3e-13
IHMCCOPL_00725 1.4e-229 2.7.13.3 T GHKL domain
IHMCCOPL_00726 1.5e-132 agrA KT phosphorelay signal transduction system
IHMCCOPL_00727 1.9e-50 L transposase and inactivated derivatives, IS30 family
IHMCCOPL_00728 7.4e-40 L Integrase core domain
IHMCCOPL_00729 8.3e-159 2.7.13.3 T Histidine kinase
IHMCCOPL_00730 1.4e-103 T Transcriptional regulatory protein, C terminal
IHMCCOPL_00731 5.5e-79
IHMCCOPL_00732 1.2e-122 S ABC-2 family transporter protein
IHMCCOPL_00733 2.8e-123 V AAA domain, putative AbiEii toxin, Type IV TA system
IHMCCOPL_00734 0.0 V ABC transporter transmembrane region
IHMCCOPL_00735 1.4e-32 S Coenzyme PQQ synthesis protein D (PqqD)
IHMCCOPL_00736 8.7e-203 6.3.5.4 E Asparagine synthase
IHMCCOPL_00738 5.2e-59 L Transposase and inactivated derivatives
IHMCCOPL_00739 7.8e-83 L Transposase
IHMCCOPL_00741 8.9e-136 agrA KT response regulator
IHMCCOPL_00742 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IHMCCOPL_00744 7.7e-09
IHMCCOPL_00745 5.2e-162 K sequence-specific DNA binding
IHMCCOPL_00746 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IHMCCOPL_00747 3e-84 yxjI S LURP-one-related
IHMCCOPL_00748 3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
IHMCCOPL_00749 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
IHMCCOPL_00750 1.4e-210 oxlT P COG0477 Permeases of the major facilitator superfamily
IHMCCOPL_00751 0.0 pepF E oligoendopeptidase F
IHMCCOPL_00752 4.7e-174 coiA 3.6.4.12 S Competence protein
IHMCCOPL_00753 2.6e-264 S Glucan-binding protein C
IHMCCOPL_00754 5.5e-106 S CAAX amino terminal protease family protein
IHMCCOPL_00755 4.7e-168 K transcriptional regulator (lysR family)
IHMCCOPL_00756 3.4e-160 S reductase
IHMCCOPL_00757 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHMCCOPL_00761 2.4e-187 phoH T phosphate starvation-inducible protein PhoH
IHMCCOPL_00762 3.6e-129 sip M LysM domain protein
IHMCCOPL_00763 3.7e-34 yozE S Belongs to the UPF0346 family
IHMCCOPL_00764 6.5e-159 cvfB S Protein conserved in bacteria
IHMCCOPL_00765 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IHMCCOPL_00766 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IHMCCOPL_00767 1.2e-214 sptS 2.7.13.3 T Histidine kinase
IHMCCOPL_00768 6.4e-117 T response regulator
IHMCCOPL_00769 3.3e-112 2.7.6.5 S Region found in RelA / SpoT proteins
IHMCCOPL_00770 7.4e-112 K Acetyltransferase (GNAT) family
IHMCCOPL_00771 0.0 lmrA2 V abc transporter atp-binding protein
IHMCCOPL_00772 0.0 lmrA1 V abc transporter atp-binding protein
IHMCCOPL_00773 3e-75 K DNA-binding transcription factor activity
IHMCCOPL_00774 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IHMCCOPL_00775 1.7e-269 S Psort location CytoplasmicMembrane, score
IHMCCOPL_00776 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IHMCCOPL_00777 5.5e-211 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
IHMCCOPL_00778 3.1e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
IHMCCOPL_00779 1.3e-26 U response to pH
IHMCCOPL_00780 0.0 yfmR S abc transporter atp-binding protein
IHMCCOPL_00781 3.3e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IHMCCOPL_00782 1.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IHMCCOPL_00783 8.1e-146 XK27_08360 S EDD domain protein, DegV family
IHMCCOPL_00784 5e-63 WQ51_03320 S cog cog4835
IHMCCOPL_00785 1.4e-130 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHMCCOPL_00786 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IHMCCOPL_00787 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IHMCCOPL_00788 3.9e-93 2.3.1.128 K acetyltransferase
IHMCCOPL_00789 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IHMCCOPL_00790 1.5e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IHMCCOPL_00791 1.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHMCCOPL_00792 2.4e-209 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IHMCCOPL_00794 6.5e-224 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IHMCCOPL_00795 3.1e-256 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHMCCOPL_00796 0.0 fruA 2.7.1.202 G phosphotransferase system
IHMCCOPL_00797 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IHMCCOPL_00798 3.4e-23 fruR K transcriptional
IHMCCOPL_00799 1.6e-264 V ABC transporter transmembrane region
IHMCCOPL_00800 5.1e-237
IHMCCOPL_00801 0.0
IHMCCOPL_00802 3.1e-221 L viral genome integration into host DNA
IHMCCOPL_00803 9.2e-98
IHMCCOPL_00804 2e-171 K Probable Zinc-ribbon domain
IHMCCOPL_00805 0.0 S dextransucrase activity
IHMCCOPL_00806 0.0 S dextransucrase activity
IHMCCOPL_00816 1.5e-48 GM domain, Protein
IHMCCOPL_00817 1.7e-10
IHMCCOPL_00818 1.8e-180 XK27_10075 S abc transporter atp-binding protein
IHMCCOPL_00819 0.0 V abc transporter atp-binding protein
IHMCCOPL_00820 1.6e-297 V abc transporter atp-binding protein
IHMCCOPL_00821 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
IHMCCOPL_00823 2.2e-282 S Protein of unknown function (DUF3114)
IHMCCOPL_00824 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
IHMCCOPL_00825 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IHMCCOPL_00826 3.5e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
IHMCCOPL_00827 5.7e-187 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
IHMCCOPL_00828 2.2e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IHMCCOPL_00829 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IHMCCOPL_00830 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IHMCCOPL_00831 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IHMCCOPL_00832 3.3e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IHMCCOPL_00833 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IHMCCOPL_00834 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IHMCCOPL_00837 1.8e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHMCCOPL_00838 1.9e-170 vraS 2.7.13.3 T Histidine kinase
IHMCCOPL_00839 1.7e-117 yvqF S Membrane
IHMCCOPL_00840 4.1e-104 kcsA P Ion transport protein
IHMCCOPL_00841 1.8e-294 prkC 2.7.11.1 KLT serine threonine protein kinase
IHMCCOPL_00842 1.3e-134 stp 3.1.3.16 T phosphatase
IHMCCOPL_00843 8.6e-243 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IHMCCOPL_00844 4.7e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IHMCCOPL_00845 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHMCCOPL_00846 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
IHMCCOPL_00847 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IHMCCOPL_00848 3.8e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IHMCCOPL_00849 1e-145 XK27_02985 S overlaps another CDS with the same product name
IHMCCOPL_00850 5.9e-146 supH S overlaps another CDS with the same product name
IHMCCOPL_00851 5.6e-62 yvoA_1 K Transcriptional
IHMCCOPL_00852 1.8e-119 skfE V abc transporter atp-binding protein
IHMCCOPL_00853 8.4e-129 V Psort location CytoplasmicMembrane, score
IHMCCOPL_00854 1.2e-171 oppF P Belongs to the ABC transporter superfamily
IHMCCOPL_00855 4.2e-203 oppD P Belongs to the ABC transporter superfamily
IHMCCOPL_00856 3.8e-165 amiD P ABC transporter (Permease
IHMCCOPL_00857 2.1e-274 amiC P ABC transporter (Permease
IHMCCOPL_00858 1.4e-310 amiA E ABC transporter, substrate-binding protein, family 5
IHMCCOPL_00859 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IHMCCOPL_00860 2e-175 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IHMCCOPL_00861 1e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IHMCCOPL_00862 1.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHMCCOPL_00863 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
IHMCCOPL_00864 2.4e-101 yjbK S Adenylate cyclase
IHMCCOPL_00865 8.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHMCCOPL_00866 5.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
IHMCCOPL_00867 2.4e-59 XK27_04120 S Putative amino acid metabolism
IHMCCOPL_00868 2.8e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IHMCCOPL_00869 3.2e-132 puuD T peptidase C26
IHMCCOPL_00870 2.4e-119 radC E Belongs to the UPF0758 family
IHMCCOPL_00871 1.2e-278 rgpF M Rhamnan synthesis protein F
IHMCCOPL_00872 2.8e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IHMCCOPL_00873 8.9e-142 rgpC GM Transport permease protein
IHMCCOPL_00874 1.4e-175 rgpB GT2 M Glycosyltransferase, group 2 family protein
IHMCCOPL_00875 1.6e-224 rgpA GT4 M Domain of unknown function (DUF1972)
IHMCCOPL_00876 1.7e-229 GT4 M transferase activity, transferring glycosyl groups
IHMCCOPL_00877 5e-221 M Psort location CytoplasmicMembrane, score
IHMCCOPL_00878 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
IHMCCOPL_00879 2.3e-123
IHMCCOPL_00880 3.2e-149 2.4.1.60 S Glycosyltransferase group 2 family protein
IHMCCOPL_00881 1.4e-43 S Uncharacterized conserved protein (DUF2304)
IHMCCOPL_00882 3.2e-127 arnC M group 2 family protein
IHMCCOPL_00883 1.6e-177 cpsIaJ S Glycosyltransferase like family 2
IHMCCOPL_00884 1.4e-154 M Glycosyltransferase, group 2 family protein
IHMCCOPL_00885 8.4e-227 amrA S membrane protein involved in the export of O-antigen and teichoic acid
IHMCCOPL_00886 1.7e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IHMCCOPL_00887 9.2e-262 S Glucosyl transferase GtrII
IHMCCOPL_00888 2.3e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
IHMCCOPL_00889 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
IHMCCOPL_00890 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IHMCCOPL_00891 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IHMCCOPL_00892 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IHMCCOPL_00893 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IHMCCOPL_00894 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
IHMCCOPL_00895 4e-201 arcT 2.6.1.1 E Aminotransferase
IHMCCOPL_00896 2.2e-137 ET Belongs to the bacterial solute-binding protein 3 family
IHMCCOPL_00897 1.2e-138 ET ABC transporter
IHMCCOPL_00898 2e-45 mutT 3.6.1.55 F Nudix family
IHMCCOPL_00899 2.1e-23 mutT 3.6.1.55 F Nudix family
IHMCCOPL_00900 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IHMCCOPL_00902 8.7e-157 S CAAX amino terminal protease family protein
IHMCCOPL_00903 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
IHMCCOPL_00904 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHMCCOPL_00905 1.7e-17 XK27_00735
IHMCCOPL_00906 1.5e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IHMCCOPL_00908 1.6e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IHMCCOPL_00909 9.8e-10 O ADP-ribosylglycohydrolase
IHMCCOPL_00910 7.4e-62 paaI Q protein possibly involved in aromatic compounds catabolism
IHMCCOPL_00911 3.5e-61 ycaO O OsmC-like protein
IHMCCOPL_00913 1.7e-149 EG Permeases of the drug metabolite transporter (DMT) superfamily
IHMCCOPL_00914 6.5e-08 N PFAM Uncharacterised protein family UPF0150
IHMCCOPL_00915 1.9e-110 serB 3.1.3.3 E phosphoserine phosphatase
IHMCCOPL_00916 6.4e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IHMCCOPL_00917 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHMCCOPL_00918 9.3e-98 3.1.3.18 S IA, variant 1
IHMCCOPL_00919 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IHMCCOPL_00920 7.7e-56 lrgA S Effector of murein hydrolase LrgA
IHMCCOPL_00922 5.4e-68 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
IHMCCOPL_00923 3.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHMCCOPL_00924 1.1e-103 wecD M Acetyltransferase (GNAT) domain
IHMCCOPL_00925 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHMCCOPL_00926 1.1e-156 GK ROK family
IHMCCOPL_00927 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
IHMCCOPL_00928 1.6e-144 XK27_08050 O HflC and HflK could regulate a protease
IHMCCOPL_00929 1.3e-204 potD P spermidine putrescine ABC transporter
IHMCCOPL_00930 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
IHMCCOPL_00931 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
IHMCCOPL_00932 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IHMCCOPL_00933 2.1e-168 murB 1.3.1.98 M cell wall formation
IHMCCOPL_00934 3.7e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IHMCCOPL_00935 4.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IHMCCOPL_00936 2.8e-295 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
IHMCCOPL_00937 5.9e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IHMCCOPL_00938 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
IHMCCOPL_00939 0.0 ydaO E amino acid
IHMCCOPL_00940 4.5e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IHMCCOPL_00941 1.5e-36 ylqC L Belongs to the UPF0109 family
IHMCCOPL_00942 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IHMCCOPL_00944 1.7e-35 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IHMCCOPL_00945 1.6e-143 S Phenazine biosynthesis protein
IHMCCOPL_00946 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
IHMCCOPL_00947 1.3e-132 cbiQ P Cobalt transport protein
IHMCCOPL_00948 1.3e-156 P abc transporter atp-binding protein
IHMCCOPL_00949 2e-149 cbiO2 P ABC transporter, ATP-binding protein
IHMCCOPL_00950 3e-86 L COG1943 Transposase and inactivated derivatives
IHMCCOPL_00951 1.4e-07 S dextransucrase activity
IHMCCOPL_00952 5.6e-181 S dextransucrase activity
IHMCCOPL_00953 0.0 M Putative cell wall binding repeat
IHMCCOPL_00954 1.5e-173 S dextransucrase activity
IHMCCOPL_00955 6.2e-258 M Putative cell wall binding repeat
IHMCCOPL_00956 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IHMCCOPL_00957 8.6e-102 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IHMCCOPL_00958 0.0 S dextransucrase activity
IHMCCOPL_00959 3.6e-88 S dextransucrase activity
IHMCCOPL_00960 0.0 S dextransucrase activity
IHMCCOPL_00961 3.1e-35
IHMCCOPL_00962 3.4e-19
IHMCCOPL_00965 1.1e-72
IHMCCOPL_00966 1.3e-83 V ABC transporter
IHMCCOPL_00968 1.3e-103 mutH L DNA mismatch repair enzyme MutH
IHMCCOPL_00969 3.5e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
IHMCCOPL_00970 6.8e-67
IHMCCOPL_00971 4.9e-79 K Peptidase S24-like protein
IHMCCOPL_00972 5.7e-70 E IrrE N-terminal-like domain
IHMCCOPL_00973 9.4e-25 S Bacteriophage abortive infection AbiH
IHMCCOPL_00974 9.1e-35 K Helix-turn-helix XRE-family like proteins
IHMCCOPL_00975 8.6e-42
IHMCCOPL_00976 6.6e-73
IHMCCOPL_00977 2.4e-274 ydcQ D Ftsk spoiiie family protein
IHMCCOPL_00978 1.3e-224 K Replication initiation factor
IHMCCOPL_00979 4.3e-33
IHMCCOPL_00980 2.5e-87
IHMCCOPL_00981 4.3e-162 S Conjugative transposon protein TcpC
IHMCCOPL_00982 3.2e-33
IHMCCOPL_00983 3.5e-70 S TcpE family
IHMCCOPL_00984 0.0 yddE S AAA-like domain
IHMCCOPL_00985 2.8e-247
IHMCCOPL_00986 4.8e-29
IHMCCOPL_00987 5.6e-171 isp2 S pathogenesis
IHMCCOPL_00989 6e-42 S Helix-turn-helix domain
IHMCCOPL_00990 1.5e-193 int L Belongs to the 'phage' integrase family
IHMCCOPL_00991 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
IHMCCOPL_00992 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IHMCCOPL_00993 5.1e-22 K Transcriptional
IHMCCOPL_00995 1.2e-152 degV S DegV family
IHMCCOPL_00996 6e-91 yacP S RNA-binding protein containing a PIN domain
IHMCCOPL_00997 3.1e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHMCCOPL_00999 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IHMCCOPL_01000 5.8e-255 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IHMCCOPL_01002 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
IHMCCOPL_01003 7.9e-140 S SseB protein N-terminal domain
IHMCCOPL_01004 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IHMCCOPL_01005 4.5e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IHMCCOPL_01006 4.3e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IHMCCOPL_01007 0.0 clpC O Belongs to the ClpA ClpB family
IHMCCOPL_01008 1.8e-75 ctsR K Belongs to the CtsR family
IHMCCOPL_01009 1e-81 S Putative small multi-drug export protein
IHMCCOPL_01010 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IHMCCOPL_01011 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
IHMCCOPL_01012 2.4e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
IHMCCOPL_01013 9.2e-289 ahpF O alkyl hydroperoxide reductase
IHMCCOPL_01015 1.2e-94 S reductase
IHMCCOPL_01016 3.9e-72 badR K Transcriptional regulator, marr family
IHMCCOPL_01017 5.5e-36 XK27_02060 S Transglycosylase associated protein
IHMCCOPL_01018 1.6e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IHMCCOPL_01019 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHMCCOPL_01024 1.9e-07
IHMCCOPL_01027 2.6e-10
IHMCCOPL_01028 3e-40 L COG1943 Transposase and inactivated derivatives
IHMCCOPL_01029 1.4e-206 3.5.1.28 NU GBS Bsp-like repeat
IHMCCOPL_01030 5.1e-15
IHMCCOPL_01031 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
IHMCCOPL_01032 7.3e-141 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IHMCCOPL_01033 1e-223 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
IHMCCOPL_01034 4.1e-184 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IHMCCOPL_01035 1.1e-217 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IHMCCOPL_01036 4.3e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IHMCCOPL_01037 1.2e-205 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IHMCCOPL_01038 1.5e-134 yxkH G deacetylase
IHMCCOPL_01039 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IHMCCOPL_01040 7e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IHMCCOPL_01041 4.4e-150 rarD S Transporter
IHMCCOPL_01042 2.2e-15 T peptidase
IHMCCOPL_01043 3e-14 coiA 3.6.4.12 S Competence protein
IHMCCOPL_01044 1.4e-101 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IHMCCOPL_01045 2.4e-101 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
IHMCCOPL_01046 4e-96 F Shikimate kinase
IHMCCOPL_01047 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IHMCCOPL_01048 1.4e-147 S AAA ATPase domain
IHMCCOPL_01049 1.5e-11
IHMCCOPL_01050 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHMCCOPL_01051 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
IHMCCOPL_01052 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IHMCCOPL_01053 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHMCCOPL_01054 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IHMCCOPL_01055 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHMCCOPL_01056 1.5e-261 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IHMCCOPL_01057 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IHMCCOPL_01058 9.2e-218 ftsW D Belongs to the SEDS family
IHMCCOPL_01059 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IHMCCOPL_01060 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IHMCCOPL_01061 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IHMCCOPL_01063 2.5e-107 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHMCCOPL_01064 6e-160 holB 2.7.7.7 L dna polymerase iii
IHMCCOPL_01065 4.9e-132 yaaT S stage 0 sporulation protein
IHMCCOPL_01066 1.2e-54 yabA L Involved in initiation control of chromosome replication
IHMCCOPL_01067 6.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IHMCCOPL_01068 1.6e-227 amt P Ammonium Transporter
IHMCCOPL_01069 1.9e-53 glnB K Belongs to the P(II) protein family
IHMCCOPL_01070 7.8e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
IHMCCOPL_01071 9e-96 S HD domain
IHMCCOPL_01072 4.3e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
IHMCCOPL_01073 3.4e-81 S Bacterial inner membrane protein
IHMCCOPL_01074 7.5e-112 3.4.17.14, 3.5.1.28 NU amidase activity
IHMCCOPL_01075 3.8e-293 nptA P COG1283 Na phosphate symporter
IHMCCOPL_01076 5.8e-211 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IHMCCOPL_01077 3.1e-218 S membrane
IHMCCOPL_01078 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IHMCCOPL_01079 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IHMCCOPL_01080 1.7e-38 ynzC S UPF0291 protein
IHMCCOPL_01081 6e-255 cycA E permease
IHMCCOPL_01082 3e-07 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHMCCOPL_01083 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IHMCCOPL_01084 1.3e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHMCCOPL_01086 2.9e-68 K Helix-turn-helix
IHMCCOPL_01087 3.5e-44
IHMCCOPL_01089 9e-167 fhuR K transcriptional regulator (lysR family)
IHMCCOPL_01090 4.4e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IHMCCOPL_01091 3.2e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IHMCCOPL_01092 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IHMCCOPL_01093 4e-221 pyrP F uracil Permease
IHMCCOPL_01094 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IHMCCOPL_01095 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
IHMCCOPL_01096 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
IHMCCOPL_01097 2.1e-129 2.1.1.223 S Putative SAM-dependent methyltransferase
IHMCCOPL_01098 4.4e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHMCCOPL_01099 4.4e-121 macB V ABC transporter, ATP-binding protein
IHMCCOPL_01100 1.2e-211 V permease protein
IHMCCOPL_01101 1.1e-76 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IHMCCOPL_01102 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IHMCCOPL_01103 0.0 mdlB V abc transporter atp-binding protein
IHMCCOPL_01104 0.0 lmrA V abc transporter atp-binding protein
IHMCCOPL_01105 1.1e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IHMCCOPL_01106 8e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IHMCCOPL_01107 2.6e-196 yceA S Belongs to the UPF0176 family
IHMCCOPL_01108 1.6e-28 XK27_00085 K Transcriptional
IHMCCOPL_01109 2.3e-23
IHMCCOPL_01110 2e-135 deoD_1 2.4.2.3 F Phosphorylase superfamily
IHMCCOPL_01111 3.9e-114 S VIT family
IHMCCOPL_01112 1.6e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IHMCCOPL_01113 2.8e-213 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IHMCCOPL_01114 7.5e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
IHMCCOPL_01117 4.4e-141 E Alpha beta hydrolase
IHMCCOPL_01118 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHMCCOPL_01119 8.8e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IHMCCOPL_01120 2e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IHMCCOPL_01121 7.1e-165 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IHMCCOPL_01122 3.9e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IHMCCOPL_01123 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IHMCCOPL_01124 2.3e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IHMCCOPL_01125 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
IHMCCOPL_01126 4.6e-23
IHMCCOPL_01127 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IHMCCOPL_01128 0.0 U protein secretion
IHMCCOPL_01129 2.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
IHMCCOPL_01130 1.3e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IHMCCOPL_01131 3.8e-13
IHMCCOPL_01132 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHMCCOPL_01133 2e-161 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IHMCCOPL_01134 2.5e-200 S Protein of unknown function (DUF3114)
IHMCCOPL_01135 4.1e-29 pspC KT PspC domain protein
IHMCCOPL_01136 5.2e-119 yqfA K protein, Hemolysin III
IHMCCOPL_01137 1.1e-77 K hmm pf08876
IHMCCOPL_01138 1e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IHMCCOPL_01139 4.9e-210 mvaS 2.3.3.10 I synthase
IHMCCOPL_01140 2.7e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IHMCCOPL_01141 1.3e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHMCCOPL_01142 9.7e-22
IHMCCOPL_01143 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IHMCCOPL_01144 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IHMCCOPL_01145 2.9e-249 mmuP E amino acid
IHMCCOPL_01146 1.3e-171 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
IHMCCOPL_01147 2.2e-30 S Domain of unknown function (DUF1912)
IHMCCOPL_01148 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
IHMCCOPL_01149 6.7e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IHMCCOPL_01150 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHMCCOPL_01152 2.4e-10
IHMCCOPL_01153 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHMCCOPL_01154 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
IHMCCOPL_01155 4.8e-16 S Protein of unknown function (DUF2969)
IHMCCOPL_01158 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
IHMCCOPL_01161 1.2e-106 S Domain of Unknown Function with PDB structure (DUF3862)
IHMCCOPL_01162 6e-115 M Pfam SNARE associated Golgi protein
IHMCCOPL_01163 2.8e-227 murN 2.3.2.16 V FemAB family
IHMCCOPL_01164 5.8e-172 S oxidoreductase
IHMCCOPL_01165 1.4e-47 XK27_09445 S Domain of unknown function (DUF1827)
IHMCCOPL_01166 2.2e-84 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IHMCCOPL_01167 0.0 clpE O Belongs to the ClpA ClpB family
IHMCCOPL_01168 5.3e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IHMCCOPL_01169 1e-34 ykuJ S protein conserved in bacteria
IHMCCOPL_01170 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
IHMCCOPL_01171 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHMCCOPL_01172 3.1e-78 feoA P FeoA domain protein
IHMCCOPL_01173 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IHMCCOPL_01174 6.6e-08
IHMCCOPL_01175 1.3e-150 I Alpha/beta hydrolase family
IHMCCOPL_01176 1.4e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IHMCCOPL_01177 1.2e-146 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IHMCCOPL_01178 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
IHMCCOPL_01179 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IHMCCOPL_01180 2e-144 licT K antiterminator
IHMCCOPL_01181 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IHMCCOPL_01182 9.8e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IHMCCOPL_01183 2.2e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IHMCCOPL_01184 5.8e-149 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IHMCCOPL_01185 1.2e-98 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IHMCCOPL_01186 3.2e-220 mdtG EGP Major facilitator Superfamily
IHMCCOPL_01187 2e-33 secG U Preprotein translocase subunit SecG
IHMCCOPL_01188 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IHMCCOPL_01189 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IHMCCOPL_01190 1.4e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHMCCOPL_01191 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
IHMCCOPL_01192 6.4e-196 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
IHMCCOPL_01193 3.2e-181 ccpA K Catabolite control protein A
IHMCCOPL_01194 2.9e-201 yyaQ S YjbR
IHMCCOPL_01195 1.4e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IHMCCOPL_01196 3.9e-78 yueI S Protein of unknown function (DUF1694)
IHMCCOPL_01197 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IHMCCOPL_01198 6.3e-205 S Phage integrase family
IHMCCOPL_01200 1.8e-20 E Pfam:DUF955
IHMCCOPL_01201 6.1e-50 S protein disulfide oxidoreductase activity
IHMCCOPL_01204 2.8e-81 K BRO family, N-terminal domain
IHMCCOPL_01207 5.9e-25
IHMCCOPL_01208 1e-24 S calcium ion binding
IHMCCOPL_01211 3.1e-76 M Pilin isopeptide linkage domain protein
IHMCCOPL_01214 2e-67 S DNA metabolic process
IHMCCOPL_01215 1.6e-52 S Protein of unknown function (DUF1351)
IHMCCOPL_01216 1.3e-47
IHMCCOPL_01217 7.2e-65 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IHMCCOPL_01218 2.5e-25 3.1.22.4
IHMCCOPL_01220 1.9e-09
IHMCCOPL_01224 5.2e-20 S Protein of unknown function (DUF1642)
IHMCCOPL_01227 9.5e-63 S Protein of unknown function (DUF1492)
IHMCCOPL_01228 6.7e-96 yqaS L DNA packaging
IHMCCOPL_01229 2e-228 L Phage terminase, large subunit
IHMCCOPL_01230 1.9e-227 S portal protein
IHMCCOPL_01231 3.5e-198 S Phage minor capsid protein 2
IHMCCOPL_01232 2.2e-38 S Phage minor structural protein GP20
IHMCCOPL_01233 1.5e-133
IHMCCOPL_01235 8.4e-48
IHMCCOPL_01236 2.8e-26 S Minor capsid protein
IHMCCOPL_01237 1.4e-49 S Minor capsid protein
IHMCCOPL_01238 6.8e-66 S Minor capsid protein from bacteriophage
IHMCCOPL_01239 8e-73
IHMCCOPL_01240 2.6e-24
IHMCCOPL_01241 3.6e-87 S Bacteriophage Gp15 protein
IHMCCOPL_01242 8.4e-245 S transmembrane transport
IHMCCOPL_01243 1.3e-107
IHMCCOPL_01244 7.1e-171 S peptidoglycan catabolic process
IHMCCOPL_01245 3.2e-20
IHMCCOPL_01246 1.4e-45
IHMCCOPL_01247 8.2e-29 hol S Holin, phage phi LC3 family
IHMCCOPL_01248 3.6e-129 S peptidoglycan catabolic process
IHMCCOPL_01249 1.3e-46
IHMCCOPL_01250 1.8e-70 S Protein of unknown function with HXXEE motif
IHMCCOPL_01251 9.9e-97 K Transcriptional regulator, TetR family
IHMCCOPL_01252 7.6e-158 czcD P cation diffusion facilitator family transporter
IHMCCOPL_01253 2.9e-196 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IHMCCOPL_01254 3.7e-185 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
IHMCCOPL_01257 2.7e-126 ybhF_2 V abc transporter atp-binding protein
IHMCCOPL_01258 1.4e-174 ybhR V ABC transporter
IHMCCOPL_01259 1.1e-104 K Bacterial regulatory proteins, tetR family
IHMCCOPL_01260 7.5e-125 ltaE 4.1.2.48 E Beta-eliminating lyase
IHMCCOPL_01261 1.1e-92 K LysR substrate binding domain
IHMCCOPL_01262 1.9e-133 2.4.2.3 F Phosphorylase superfamily
IHMCCOPL_01263 4.3e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
IHMCCOPL_01264 0.0 V Type III restriction enzyme, res subunit
IHMCCOPL_01265 9.2e-178 yclQ P ABC-type enterochelin transport system, periplasmic component
IHMCCOPL_01266 2e-231 dinF V Mate efflux family protein
IHMCCOPL_01267 2.8e-269 S Psort location CytoplasmicMembrane, score
IHMCCOPL_01268 7.3e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IHMCCOPL_01269 4.4e-133 S TraX protein
IHMCCOPL_01270 2.7e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
IHMCCOPL_01271 3.2e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IHMCCOPL_01272 1.3e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IHMCCOPL_01273 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IHMCCOPL_01274 9.8e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHMCCOPL_01275 2.1e-242 nylA 3.5.1.4 J Belongs to the amidase family
IHMCCOPL_01276 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
IHMCCOPL_01277 6.4e-82 yecS P ABC transporter (Permease
IHMCCOPL_01278 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
IHMCCOPL_01279 7.8e-177 bglC K Transcriptional regulator
IHMCCOPL_01280 1.8e-243 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IHMCCOPL_01281 2.8e-241 agcS E (Alanine) symporter
IHMCCOPL_01282 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IHMCCOPL_01283 3.3e-239 metY 2.5.1.49 E o-acetylhomoserine
IHMCCOPL_01284 3e-139 S haloacid dehalogenase-like hydrolase
IHMCCOPL_01285 5.5e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IHMCCOPL_01286 1.3e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
IHMCCOPL_01287 1e-34 M1-755 P Hemerythrin HHE cation binding domain protein
IHMCCOPL_01288 4.6e-244 XK27_04775 S hemerythrin HHE cation binding domain
IHMCCOPL_01289 1.2e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IHMCCOPL_01290 6e-276 5.1.3.2 GM Psort location CytoplasmicMembrane, score
IHMCCOPL_01291 4.8e-144
IHMCCOPL_01292 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
IHMCCOPL_01293 6.1e-271 pelF GT4 M Domain of unknown function (DUF3492)
IHMCCOPL_01294 2.4e-182 pelG M Putative exopolysaccharide Exporter (EPS-E)
IHMCCOPL_01295 5.9e-223 cotH M CotH kinase protein
IHMCCOPL_01296 6e-97 P VTC domain
IHMCCOPL_01297 2e-83 S membrane
IHMCCOPL_01298 3.2e-134 G Domain of unknown function (DUF4832)
IHMCCOPL_01299 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IHMCCOPL_01300 3.7e-11 S Protein of unknown function (DUF1146)
IHMCCOPL_01301 3.8e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHMCCOPL_01302 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
IHMCCOPL_01303 2.2e-154 endA F DNA RNA non-specific endonuclease
IHMCCOPL_01304 5e-111 tcyB_2 P ABC transporter (permease)
IHMCCOPL_01305 1.9e-116 gltJ P ABC transporter (Permease
IHMCCOPL_01306 2e-14 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IHMCCOPL_01307 5.4e-50
IHMCCOPL_01308 5e-90 niaR S small molecule binding protein (contains 3H domain)
IHMCCOPL_01309 4e-127 K DNA-binding helix-turn-helix protein
IHMCCOPL_01310 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IHMCCOPL_01311 7.7e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHMCCOPL_01312 2e-166 GK ROK family
IHMCCOPL_01313 2.4e-158 dprA LU DNA protecting protein DprA
IHMCCOPL_01314 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHMCCOPL_01315 1.6e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
IHMCCOPL_01316 6.3e-54 V ABC-2 family transporter protein
IHMCCOPL_01318 2.8e-143 S TraX protein
IHMCCOPL_01319 2.4e-121 KT Transcriptional regulatory protein, C terminal
IHMCCOPL_01320 2.1e-220 T PhoQ Sensor
IHMCCOPL_01321 2.1e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IHMCCOPL_01322 2.7e-224 XK27_05470 E Methionine synthase
IHMCCOPL_01323 2.1e-70 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IHMCCOPL_01324 3.1e-44 pspE P Rhodanese-like protein
IHMCCOPL_01325 2.4e-136 IQ Acetoin reductase
IHMCCOPL_01328 1.1e-24
IHMCCOPL_01329 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IHMCCOPL_01330 0.0 3.5.1.28 M domain protein
IHMCCOPL_01331 2.3e-136 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
IHMCCOPL_01332 1.3e-232 L DNA binding domain of tn916 integrase
IHMCCOPL_01333 1.8e-30 xis S Excisionase from transposon Tn916
IHMCCOPL_01334 1.5e-28 S Helix-turn-helix domain
IHMCCOPL_01335 1.1e-71 phyR K Sigma-70, region 4
IHMCCOPL_01336 6e-58 K Helix-turn-helix domain
IHMCCOPL_01337 0.0 tetP J elongation factor G
IHMCCOPL_01338 4.8e-168 S Conjugative transposon protein TcpC
IHMCCOPL_01339 2.2e-190 yddH M NlpC p60 family protein
IHMCCOPL_01340 0.0 S the current gene model (or a revised gene model) may contain a frame shift
IHMCCOPL_01341 0.0 S AAA-like domain
IHMCCOPL_01342 3.8e-90 S TcpE family
IHMCCOPL_01343 7.5e-91 S Antirestriction protein (ArdA)
IHMCCOPL_01344 1.9e-30 S Psort location CytoplasmicMembrane, score
IHMCCOPL_01345 1.6e-232 K Replication initiation factor
IHMCCOPL_01346 3.7e-265 D Domain of unknown function DUF87
IHMCCOPL_01347 1e-63 S Bacterial protein of unknown function (DUF961)
IHMCCOPL_01348 2.3e-53 S Bacterial protein of unknown function (DUF961)
IHMCCOPL_01349 4.3e-87 V abc transporter atp-binding protein
IHMCCOPL_01350 2.2e-15
IHMCCOPL_01352 1.5e-73 K Transcriptional regulatory protein, C terminal
IHMCCOPL_01353 5.8e-64 2.7.13.3 T Histidine kinase
IHMCCOPL_01354 2.7e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
IHMCCOPL_01355 6.2e-67 rmaI K Transcriptional regulator, MarR family
IHMCCOPL_01356 1.1e-232 EGP Major facilitator Superfamily
IHMCCOPL_01357 2.6e-127 XK27_00785 S CAAX protease self-immunity
IHMCCOPL_01358 1.4e-119 mleR K malolactic fermentation system
IHMCCOPL_01359 1.2e-47 K Helix-turn-helix
IHMCCOPL_01360 4.5e-310 sfcA 1.1.1.38, 4.1.1.101 C malic enzyme
IHMCCOPL_01361 1.4e-162 mleP S auxin efflux carrier
IHMCCOPL_01362 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IHMCCOPL_01365 0.0 sraP UW domain, Protein
IHMCCOPL_01366 9.5e-121 L Helix-turn-helix domain
IHMCCOPL_01367 6.8e-130 L Integrase core domain protein
IHMCCOPL_01368 1.8e-279 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
IHMCCOPL_01369 5.4e-30 bipA S protein secretion
IHMCCOPL_01370 8.9e-32 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IHMCCOPL_01371 1.1e-158 fhaB M Rib/alpha-like repeat
IHMCCOPL_01372 2.9e-161 M domain protein
IHMCCOPL_01373 1e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IHMCCOPL_01374 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IHMCCOPL_01375 7.7e-126 gntR1 K transcriptional
IHMCCOPL_01376 3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IHMCCOPL_01377 3.6e-100 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IHMCCOPL_01382 5.6e-99 mreC M Involved in formation and maintenance of cell shape
IHMCCOPL_01383 2.6e-81 mreD M rod shape-determining protein MreD
IHMCCOPL_01384 4.1e-84 usp 3.5.1.28 CBM50 S CHAP domain
IHMCCOPL_01385 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHMCCOPL_01386 1.6e-216 araT 2.6.1.1 E Aminotransferase
IHMCCOPL_01387 1.6e-140 recO L Involved in DNA repair and RecF pathway recombination
IHMCCOPL_01388 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IHMCCOPL_01389 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHMCCOPL_01390 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IHMCCOPL_01391 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHMCCOPL_01392 3e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IHMCCOPL_01393 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IHMCCOPL_01394 6.4e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IHMCCOPL_01395 5.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IHMCCOPL_01396 1.3e-156 S CHAP domain
IHMCCOPL_01397 1.4e-237 purD 6.3.4.13 F Belongs to the GARS family
IHMCCOPL_01398 3.4e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IHMCCOPL_01399 3e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IHMCCOPL_01400 2.7e-174 1.1.1.169 H Ketopantoate reductase
IHMCCOPL_01401 3.3e-33
IHMCCOPL_01402 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IHMCCOPL_01403 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IHMCCOPL_01404 6.9e-69 argR K Regulates arginine biosynthesis genes
IHMCCOPL_01405 5.7e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IHMCCOPL_01406 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IHMCCOPL_01407 3.5e-79 S Protein of unknown function (DUF3021)
IHMCCOPL_01408 1.9e-69 K LytTr DNA-binding domain
IHMCCOPL_01410 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IHMCCOPL_01412 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IHMCCOPL_01413 1e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
IHMCCOPL_01414 6.7e-229 cinA 3.5.1.42 S Belongs to the CinA family
IHMCCOPL_01415 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IHMCCOPL_01416 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
IHMCCOPL_01417 0.0 zmpB M signal peptide protein, YSIRK family
IHMCCOPL_01418 0.0 GM domain, Protein
IHMCCOPL_01419 7.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IHMCCOPL_01420 0.0 sbcC L ATPase involved in DNA repair
IHMCCOPL_01422 0.0 M family 8
IHMCCOPL_01423 3e-210 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
IHMCCOPL_01424 1.4e-289 asp1 S Accessory Sec system protein Asp1
IHMCCOPL_01425 2.4e-289 asp2 3.4.11.5 S Accessory Sec system protein Asp2
IHMCCOPL_01426 1.5e-77 asp3 S Accessory Sec system protein Asp3
IHMCCOPL_01427 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IHMCCOPL_01428 5.9e-280 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IHMCCOPL_01429 2.5e-237 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IHMCCOPL_01430 2.6e-17 S Accessory secretory protein Sec Asp4
IHMCCOPL_01431 3.6e-16 S Accessory secretory protein Sec, Asp5
IHMCCOPL_01432 1.8e-184 nss M transferase activity, transferring glycosyl groups
IHMCCOPL_01433 0.0 M domain, Protein
IHMCCOPL_01434 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IHMCCOPL_01435 1.4e-257 S dextransucrase activity
IHMCCOPL_01437 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
IHMCCOPL_01438 6.7e-120 yhfC S Putative membrane peptidase family (DUF2324)
IHMCCOPL_01439 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
IHMCCOPL_01440 8.8e-14 S integral membrane protein
IHMCCOPL_01441 2.2e-176 mccF V LD-carboxypeptidase
IHMCCOPL_01442 4.1e-52 fruR K transcriptional
IHMCCOPL_01443 2.4e-207 rny D Endoribonuclease that initiates mRNA decay
IHMCCOPL_01444 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IHMCCOPL_01445 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IHMCCOPL_01446 3.9e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IHMCCOPL_01447 1.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IHMCCOPL_01448 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IHMCCOPL_01449 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IHMCCOPL_01450 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IHMCCOPL_01451 1.8e-125 IQ reductase
IHMCCOPL_01452 3e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IHMCCOPL_01453 4.4e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
IHMCCOPL_01454 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHMCCOPL_01455 1.4e-165 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHMCCOPL_01456 5.2e-72 marR K Transcriptional regulator, MarR family
IHMCCOPL_01457 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
IHMCCOPL_01458 3.5e-117 S HAD hydrolase, family IA, variant 3
IHMCCOPL_01459 1.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
IHMCCOPL_01460 9.7e-191 asnA 6.3.1.1 E aspartate--ammonia ligase
IHMCCOPL_01461 1e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHMCCOPL_01462 3.5e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
IHMCCOPL_01463 7.8e-102 ygaC J Belongs to the UPF0374 family
IHMCCOPL_01464 1.1e-220 L the current gene model (or a revised gene model) may contain a frame shift
IHMCCOPL_01465 1.5e-104 S Domain of unknown function (DUF1803)
IHMCCOPL_01466 3.9e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
IHMCCOPL_01467 0.0 M domain protein
IHMCCOPL_01468 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IHMCCOPL_01471 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IHMCCOPL_01472 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IHMCCOPL_01473 2.2e-73 mgrA K Transcriptional regulator, MarR family
IHMCCOPL_01474 1.1e-147 1.6.5.2 GM epimerase
IHMCCOPL_01475 3.9e-128 proV E ATPases associated with a variety of cellular activities
IHMCCOPL_01476 6.1e-261 proWX P ABC transporter
IHMCCOPL_01477 1.6e-247 V ABC transporter (Permease
IHMCCOPL_01478 1.8e-44
IHMCCOPL_01479 3.8e-54 D Plasmid stabilization system
IHMCCOPL_01480 1.6e-64
IHMCCOPL_01481 2e-140 S Alpha beta hydrolase
IHMCCOPL_01482 6.9e-139 S CAAX protease self-immunity
IHMCCOPL_01483 7.4e-158 K DNA-binding helix-turn-helix protein
IHMCCOPL_01484 3.3e-20 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IHMCCOPL_01485 3.4e-156
IHMCCOPL_01486 1.5e-120 Z012_10770 M Domain of unknown function (DUF1919)
IHMCCOPL_01487 7.6e-211 wcoF M Glycosyltransferase, group 1 family protein
IHMCCOPL_01488 3.1e-220 rgpAc GT4 M group 1 family protein
IHMCCOPL_01489 1e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IHMCCOPL_01490 2.6e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
IHMCCOPL_01491 1.3e-109 cps4C M biosynthesis protein
IHMCCOPL_01492 2.6e-132 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
IHMCCOPL_01493 6.8e-249 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
IHMCCOPL_01494 9.9e-132 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
IHMCCOPL_01495 1.4e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
IHMCCOPL_01496 4.5e-177 clcA_2 P Chloride transporter, ClC family
IHMCCOPL_01497 3.2e-50 S LemA family
IHMCCOPL_01498 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IHMCCOPL_01499 2.7e-86 S Protein of unknown function (DUF1697)
IHMCCOPL_01500 1.3e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IHMCCOPL_01501 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IHMCCOPL_01502 1.6e-252 V Glucan-binding protein C
IHMCCOPL_01503 3.8e-227 V Glucan-binding protein C
IHMCCOPL_01504 3.6e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
IHMCCOPL_01505 8.5e-273 pepV 3.5.1.18 E Dipeptidase
IHMCCOPL_01506 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IHMCCOPL_01507 2.7e-117 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IHMCCOPL_01508 1.1e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
IHMCCOPL_01509 2.6e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
IHMCCOPL_01510 1.6e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IHMCCOPL_01511 3.2e-187 tcsA S membrane
IHMCCOPL_01512 3e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IHMCCOPL_01513 4.6e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IHMCCOPL_01514 4.3e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IHMCCOPL_01515 2.4e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
IHMCCOPL_01516 2.8e-171 coaA 2.7.1.33 F Pantothenic acid kinase
IHMCCOPL_01517 1e-29 rpsT J Binds directly to 16S ribosomal RNA
IHMCCOPL_01518 1.3e-241 T PhoQ Sensor
IHMCCOPL_01519 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHMCCOPL_01520 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IHMCCOPL_01521 1.1e-116 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
IHMCCOPL_01522 3.1e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IHMCCOPL_01523 4.1e-93 panT S ECF transporter, substrate-specific component
IHMCCOPL_01524 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IHMCCOPL_01525 7.3e-166 metF 1.5.1.20 E reductase
IHMCCOPL_01526 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IHMCCOPL_01528 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
IHMCCOPL_01529 0.0 3.6.3.8 P cation transport ATPase
IHMCCOPL_01530 6.3e-243 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IHMCCOPL_01531 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHMCCOPL_01532 1.2e-235 dltB M Membrane protein involved in D-alanine export
IHMCCOPL_01533 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHMCCOPL_01534 0.0 XK27_10035 V abc transporter atp-binding protein
IHMCCOPL_01535 2.2e-291 yfiB1 V abc transporter atp-binding protein
IHMCCOPL_01536 4.1e-99 pvaA M lytic transglycosylase activity
IHMCCOPL_01537 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
IHMCCOPL_01538 6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IHMCCOPL_01539 3.2e-104 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IHMCCOPL_01540 1.2e-144 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IHMCCOPL_01541 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IHMCCOPL_01542 3.9e-110 tdk 2.7.1.21 F thymidine kinase
IHMCCOPL_01543 2.4e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IHMCCOPL_01544 1.5e-11 K sequence-specific DNA binding
IHMCCOPL_01545 5.2e-145 V ABC transporter, ATP-binding protein
IHMCCOPL_01546 2.3e-80 S ABC-2 family transporter protein
IHMCCOPL_01547 1.6e-16 fhaB M Rib/alpha-like repeat
IHMCCOPL_01548 4.1e-17 M COG3209 Rhs family protein
IHMCCOPL_01553 0.0 M domain protein
IHMCCOPL_01554 5.4e-152 M domain protein
IHMCCOPL_01555 6.9e-51
IHMCCOPL_01556 1.2e-81 3.1.21.3 V type I restriction modification DNA specificity domain
IHMCCOPL_01557 1.1e-238 S KAP family P-loop domain
IHMCCOPL_01558 2e-19 S Protein conserved in bacteria
IHMCCOPL_01559 2.3e-44 S Protein conserved in bacteria
IHMCCOPL_01560 5.6e-305 hsdM 2.1.1.72 V type I restriction-modification system
IHMCCOPL_01561 7.6e-137 S double-stranded DNA endodeoxyribonuclease activity
IHMCCOPL_01563 0.0 2.4.1.21 GT5 M Right handed beta helix region
IHMCCOPL_01564 1.7e-174 spd F DNA RNA non-specific endonuclease
IHMCCOPL_01565 7.7e-92 lemA S LemA family
IHMCCOPL_01566 4e-135 htpX O Belongs to the peptidase M48B family
IHMCCOPL_01567 1.4e-118 sirR K iron dependent repressor
IHMCCOPL_01568 2.8e-171 sitA P Belongs to the bacterial solute-binding protein 9 family
IHMCCOPL_01569 1.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
IHMCCOPL_01570 1.6e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
IHMCCOPL_01571 4.1e-73 S Psort location CytoplasmicMembrane, score
IHMCCOPL_01572 5.6e-65 S Domain of unknown function (DUF4430)
IHMCCOPL_01573 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IHMCCOPL_01574 2.1e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
IHMCCOPL_01575 1.6e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
IHMCCOPL_01576 1.1e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
IHMCCOPL_01577 2.4e-105 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
IHMCCOPL_01578 1.1e-89 dps P Belongs to the Dps family
IHMCCOPL_01579 3.4e-79 perR P Belongs to the Fur family
IHMCCOPL_01580 7.1e-27 yqgQ S protein conserved in bacteria
IHMCCOPL_01581 2.7e-177 glk 2.7.1.2 G Glucokinase
IHMCCOPL_01582 0.0 typA T GTP-binding protein TypA
IHMCCOPL_01584 7.4e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IHMCCOPL_01585 1.2e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHMCCOPL_01586 2.9e-130 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IHMCCOPL_01587 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IHMCCOPL_01588 1.6e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IHMCCOPL_01589 6.6e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IHMCCOPL_01590 1.8e-99 sepF D cell septum assembly
IHMCCOPL_01591 2.9e-30 yggT D integral membrane protein
IHMCCOPL_01592 1.5e-144 ylmH S conserved protein, contains S4-like domain
IHMCCOPL_01593 8.4e-138 divIVA D Cell division initiation protein
IHMCCOPL_01594 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IHMCCOPL_01595 3.6e-182 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHMCCOPL_01596 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHMCCOPL_01597 2.2e-34 nrdH O Glutaredoxin
IHMCCOPL_01598 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IHMCCOPL_01599 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
IHMCCOPL_01600 2.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
IHMCCOPL_01601 3e-38 ptsH G phosphocarrier protein Hpr
IHMCCOPL_01602 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IHMCCOPL_01603 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
IHMCCOPL_01604 5.1e-161 XK27_05670 S Putative esterase
IHMCCOPL_01605 2.7e-153 XK27_05675 S Esterase
IHMCCOPL_01606 1.1e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
IHMCCOPL_01607 3.3e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
IHMCCOPL_01608 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
IHMCCOPL_01609 0.0 uup S abc transporter atp-binding protein
IHMCCOPL_01610 1.6e-39 MA20_06245 S yiaA/B two helix domain
IHMCCOPL_01611 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
IHMCCOPL_01612 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IHMCCOPL_01613 2.3e-150 cobQ S glutamine amidotransferase
IHMCCOPL_01614 3.2e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
IHMCCOPL_01615 6.9e-122 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IHMCCOPL_01616 3.8e-163 ybbR S Protein conserved in bacteria
IHMCCOPL_01617 1.3e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHMCCOPL_01618 1.3e-64 gtrA S GtrA-like protein
IHMCCOPL_01619 2.2e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
IHMCCOPL_01620 1.3e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IHMCCOPL_01621 8.2e-143 zupT P Mediates zinc uptake. May also transport other divalent cations
IHMCCOPL_01622 1.5e-200 yurR 1.4.5.1 E oxidoreductase
IHMCCOPL_01623 4e-256 S phospholipase Carboxylesterase
IHMCCOPL_01624 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IHMCCOPL_01625 5.4e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IHMCCOPL_01626 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IHMCCOPL_01628 2.2e-30 KT response to antibiotic
IHMCCOPL_01629 3.2e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
IHMCCOPL_01630 1e-139 fat 3.1.2.21 I Acyl-ACP thioesterase
IHMCCOPL_01631 2.1e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IHMCCOPL_01632 2.7e-117 ylfI S tigr01906
IHMCCOPL_01633 4.2e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
IHMCCOPL_01634 1.7e-268 L Transposase
IHMCCOPL_01635 1.4e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IHMCCOPL_01636 2.8e-61 XK27_08085
IHMCCOPL_01637 8.5e-193 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IHMCCOPL_01638 2.9e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IHMCCOPL_01639 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IHMCCOPL_01640 9.2e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IHMCCOPL_01641 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IHMCCOPL_01642 2.6e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IHMCCOPL_01643 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IHMCCOPL_01644 6.2e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IHMCCOPL_01645 1.1e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IHMCCOPL_01646 2e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IHMCCOPL_01649 4.6e-149 srtB 3.4.22.70 S Sortase family
IHMCCOPL_01650 1.3e-232 capA M Bacterial capsule synthesis protein
IHMCCOPL_01651 6.1e-39 gcvR T UPF0237 protein
IHMCCOPL_01652 2.3e-243 XK27_08635 S UPF0210 protein
IHMCCOPL_01653 2.8e-131 ais G Phosphoglycerate mutase
IHMCCOPL_01654 5.3e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IHMCCOPL_01655 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
IHMCCOPL_01656 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IHMCCOPL_01657 9.1e-63 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IHMCCOPL_01658 6e-303 dnaK O Heat shock 70 kDa protein
IHMCCOPL_01659 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IHMCCOPL_01660 4.5e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IHMCCOPL_01661 2e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
IHMCCOPL_01662 7.4e-80 hmpT S cog cog4720
IHMCCOPL_01663 4.4e-141 L Helix-turn-helix domain of transposase family ISL3
IHMCCOPL_01664 4.8e-201 2.7.13.3 T protein histidine kinase activity
IHMCCOPL_01665 3.4e-124 agrA KT phosphorelay signal transduction system
IHMCCOPL_01666 7.7e-159 O protein import
IHMCCOPL_01667 3.9e-167 tehB 2.1.1.265 PQ tellurite resistance protein tehb
IHMCCOPL_01668 3.7e-17 yjdB S Domain of unknown function (DUF4767)
IHMCCOPL_01669 5.5e-200 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHMCCOPL_01671 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
IHMCCOPL_01672 3.4e-72 S QueT transporter
IHMCCOPL_01674 1.2e-172 yfjR K regulation of single-species biofilm formation
IHMCCOPL_01676 3.8e-182 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IHMCCOPL_01677 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IHMCCOPL_01678 1.3e-121 L overlaps another CDS with the same product name
IHMCCOPL_01679 8.5e-47 L Helix-turn-helix domain
IHMCCOPL_01680 7.6e-116 bcrA V abc transporter atp-binding protein
IHMCCOPL_01681 2e-116 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
IHMCCOPL_01682 7.5e-112 K Bacterial regulatory proteins, tetR family
IHMCCOPL_01683 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHMCCOPL_01684 5.9e-55
IHMCCOPL_01685 8.7e-60
IHMCCOPL_01686 1.1e-49
IHMCCOPL_01687 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
IHMCCOPL_01688 2e-217 EGP Transmembrane secretion effector
IHMCCOPL_01689 4.3e-22
IHMCCOPL_01690 9.9e-109 L DNA alkylation repair enzyme
IHMCCOPL_01691 1.6e-160 aph 2.7.11.1 KLT Aminoglycoside phosphotransferase
IHMCCOPL_01692 1.7e-52 K Transcriptional regulator
IHMCCOPL_01693 5.4e-33 S Protein of unknown function (DUF1648)
IHMCCOPL_01694 1e-255 6.1.1.6 S Psort location CytoplasmicMembrane, score
IHMCCOPL_01695 8.1e-131 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
IHMCCOPL_01696 2.1e-106 K Transcriptional regulator
IHMCCOPL_01697 4e-94 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IHMCCOPL_01698 8.5e-101 S SIR2-like domain
IHMCCOPL_01699 1.9e-167 S cog cog0433
IHMCCOPL_01700 2.4e-75 ccl S cog cog4708
IHMCCOPL_01701 3.7e-163 rbn E Belongs to the UPF0761 family
IHMCCOPL_01702 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IHMCCOPL_01703 3e-232 ytoI K transcriptional regulator containing CBS domains
IHMCCOPL_01704 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
IHMCCOPL_01705 2.1e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHMCCOPL_01706 0.0 comEC S Competence protein ComEC
IHMCCOPL_01707 4.3e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IHMCCOPL_01708 2.9e-142 plsC 2.3.1.51 I Acyltransferase
IHMCCOPL_01709 8.1e-147 nodB3 G Polysaccharide deacetylase
IHMCCOPL_01710 3.9e-139 yabB 2.1.1.223 L Methyltransferase
IHMCCOPL_01711 3.9e-41 yazA L endonuclease containing a URI domain
IHMCCOPL_01712 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IHMCCOPL_01713 1.6e-152 corA P CorA-like protein
IHMCCOPL_01714 3.3e-62 yjqA S Bacterial PH domain
IHMCCOPL_01715 5.1e-99 thiT S Thiamine transporter
IHMCCOPL_01716 3.1e-153 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IHMCCOPL_01717 4.4e-190 yjbB G Permeases of the major facilitator superfamily
IHMCCOPL_01718 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IHMCCOPL_01719 9.6e-118 ywaF S Integral membrane protein (intg_mem_TP0381)
IHMCCOPL_01720 2e-250 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IHMCCOPL_01724 5.6e-121 L Helix-turn-helix domain
IHMCCOPL_01725 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IHMCCOPL_01726 6.3e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
IHMCCOPL_01727 1e-119 sdaAB 4.3.1.17 E L-serine dehydratase
IHMCCOPL_01728 2e-147 sdaAA 4.3.1.17 E L-serine dehydratase
IHMCCOPL_01729 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
IHMCCOPL_01730 5.8e-162 T Diguanylate cyclase
IHMCCOPL_01732 3.2e-147 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
IHMCCOPL_01733 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
IHMCCOPL_01734 0.0
IHMCCOPL_01738 5.7e-117 nudL L hydrolase
IHMCCOPL_01739 6.3e-54 K transcriptional regulator, PadR family
IHMCCOPL_01740 1.9e-61 XK27_06920 S Protein of unknown function (DUF1700)
IHMCCOPL_01741 2.8e-106 S Putative adhesin
IHMCCOPL_01742 7.3e-160 XK27_06930 V domain protein
IHMCCOPL_01743 9.9e-97 XK27_06935 K transcriptional regulator
IHMCCOPL_01744 4.1e-54 ypaA M Membrane
IHMCCOPL_01745 1.9e-10
IHMCCOPL_01746 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IHMCCOPL_01747 1.8e-47 veg S Biofilm formation stimulator VEG
IHMCCOPL_01748 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IHMCCOPL_01749 2.2e-73 rplI J binds to the 23S rRNA
IHMCCOPL_01750 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IHMCCOPL_01751 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IHMCCOPL_01752 4.2e-99 yvbG U UPF0056 membrane protein
IHMCCOPL_01753 2.8e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IHMCCOPL_01754 0.0 S Bacterial membrane protein, YfhO
IHMCCOPL_01755 6.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
IHMCCOPL_01756 1e-70 lytE M LysM domain protein
IHMCCOPL_01757 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHMCCOPL_01758 6.2e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHMCCOPL_01759 1.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHMCCOPL_01760 1.2e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHMCCOPL_01761 1.1e-129 S sequence-specific DNA binding
IHMCCOPL_01762 2.8e-238 ymfH S Peptidase M16
IHMCCOPL_01763 7.1e-231 ymfF S Peptidase M16
IHMCCOPL_01764 3.7e-58 yaaA S S4 domain protein YaaA
IHMCCOPL_01765 3.6e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IHMCCOPL_01766 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IHMCCOPL_01767 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IHMCCOPL_01768 7.1e-153 yvjA S membrane
IHMCCOPL_01769 1.1e-305 ybiT S abc transporter atp-binding protein
IHMCCOPL_01770 0.0 XK27_10405 S Bacterial membrane protein YfhO
IHMCCOPL_01774 1.4e-119 yoaK S Protein of unknown function (DUF1275)
IHMCCOPL_01775 2.3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IHMCCOPL_01776 1.5e-204 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IHMCCOPL_01777 2.6e-135 parB K Belongs to the ParB family
IHMCCOPL_01778 3.8e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHMCCOPL_01779 4.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IHMCCOPL_01780 1.1e-29 yyzM S Protein conserved in bacteria
IHMCCOPL_01781 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IHMCCOPL_01782 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IHMCCOPL_01783 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IHMCCOPL_01784 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IHMCCOPL_01785 3e-60 divIC D Septum formation initiator
IHMCCOPL_01787 7.6e-236 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
IHMCCOPL_01788 9.1e-234 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IHMCCOPL_01789 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IHMCCOPL_01790 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHMCCOPL_01793 1.9e-86 sigH K DNA-templated transcription, initiation
IHMCCOPL_01794 1e-137 ykuT M mechanosensitive ion channel
IHMCCOPL_01795 2e-228 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IHMCCOPL_01796 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IHMCCOPL_01797 1.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IHMCCOPL_01798 3.8e-84 XK27_03960 S Protein of unknown function (DUF3013)
IHMCCOPL_01799 2.4e-75 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
IHMCCOPL_01800 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
IHMCCOPL_01801 3.2e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IHMCCOPL_01802 6.5e-66 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IHMCCOPL_01803 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IHMCCOPL_01804 3.1e-83 nrdI F Belongs to the NrdI family
IHMCCOPL_01805 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHMCCOPL_01806 4.8e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IHMCCOPL_01807 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IHMCCOPL_01808 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IHMCCOPL_01809 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IHMCCOPL_01810 3.4e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IHMCCOPL_01811 4.2e-193 yhjX P Major Facilitator
IHMCCOPL_01812 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IHMCCOPL_01813 2e-82 V VanZ like family
IHMCCOPL_01814 4.8e-181 D nuclear chromosome segregation
IHMCCOPL_01815 1e-123 glnQ E abc transporter atp-binding protein
IHMCCOPL_01816 3e-271 glnP P ABC transporter
IHMCCOPL_01817 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IHMCCOPL_01818 4.8e-18 S Protein of unknown function (DUF3021)
IHMCCOPL_01819 5.7e-127 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IHMCCOPL_01820 8.7e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
IHMCCOPL_01821 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IHMCCOPL_01822 6.9e-234 sufD O assembly protein SufD
IHMCCOPL_01823 5.9e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHMCCOPL_01824 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
IHMCCOPL_01825 2.9e-273 sufB O assembly protein SufB
IHMCCOPL_01826 2.7e-26
IHMCCOPL_01827 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IHMCCOPL_01828 5.3e-181 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHMCCOPL_01829 5.9e-71 adcR K transcriptional
IHMCCOPL_01830 9.2e-135 adcC P ABC transporter, ATP-binding protein
IHMCCOPL_01831 8.7e-129 adcB P ABC transporter (Permease
IHMCCOPL_01832 2.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IHMCCOPL_01833 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IHMCCOPL_01834 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
IHMCCOPL_01835 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
IHMCCOPL_01836 1.1e-150 Z012_04635 K sequence-specific DNA binding
IHMCCOPL_01837 2.3e-282 V ABC transporter
IHMCCOPL_01838 6.1e-126 yeeN K transcriptional regulatory protein
IHMCCOPL_01839 8.5e-46 yajC U protein transport
IHMCCOPL_01840 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IHMCCOPL_01841 9.3e-144 cdsA 2.7.7.41 S Belongs to the CDS family
IHMCCOPL_01842 6.5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IHMCCOPL_01843 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IHMCCOPL_01844 0.0 WQ51_06230 S ABC transporter
IHMCCOPL_01845 1.4e-142 cmpC S abc transporter atp-binding protein
IHMCCOPL_01846 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IHMCCOPL_01847 3.4e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IHMCCOPL_01849 3.8e-45
IHMCCOPL_01850 5.2e-56 S TM2 domain
IHMCCOPL_01851 3.2e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IHMCCOPL_01852 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IHMCCOPL_01853 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IHMCCOPL_01854 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
IHMCCOPL_01855 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
IHMCCOPL_01856 8.4e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
IHMCCOPL_01857 1.1e-144 cof S Sucrose-6F-phosphate phosphohydrolase
IHMCCOPL_01858 1.2e-135 glcR K transcriptional regulator (DeoR family)
IHMCCOPL_01859 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IHMCCOPL_01860 7.6e-74 K helix_turn_helix multiple antibiotic resistance protein
IHMCCOPL_01861 2.7e-230 S COG1073 Hydrolases of the alpha beta superfamily
IHMCCOPL_01862 3.9e-151 cylA V abc transporter atp-binding protein
IHMCCOPL_01863 2.4e-129 cylB V ABC-2 type transporter
IHMCCOPL_01864 9e-75 K COG3279 Response regulator of the LytR AlgR family
IHMCCOPL_01865 5.2e-32 S Protein of unknown function (DUF3021)
IHMCCOPL_01866 2e-121 mta K Transcriptional
IHMCCOPL_01867 1.8e-119 yhcA V abc transporter atp-binding protein
IHMCCOPL_01868 1.2e-217 macB_2 V FtsX-like permease family
IHMCCOPL_01869 2.5e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IHMCCOPL_01870 2.2e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IHMCCOPL_01871 1.4e-72 yhaI S Protein of unknown function (DUF805)
IHMCCOPL_01872 2.9e-254 pepC 3.4.22.40 E aminopeptidase
IHMCCOPL_01873 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IHMCCOPL_01874 1.3e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IHMCCOPL_01875 8.9e-95 ypsA S Belongs to the UPF0398 family
IHMCCOPL_01876 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IHMCCOPL_01877 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IHMCCOPL_01878 1.7e-274 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IHMCCOPL_01879 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
IHMCCOPL_01880 9.6e-23
IHMCCOPL_01881 2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IHMCCOPL_01882 2.2e-87 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
IHMCCOPL_01883 2.3e-300 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IHMCCOPL_01884 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IHMCCOPL_01885 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHMCCOPL_01886 9.2e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IHMCCOPL_01887 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHMCCOPL_01888 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
IHMCCOPL_01889 8.5e-101 ybhL S Belongs to the BI1 family
IHMCCOPL_01890 5.5e-12 ycdA S Domain of unknown function (DUF4352)
IHMCCOPL_01891 3.1e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IHMCCOPL_01892 1.8e-90 K transcriptional regulator
IHMCCOPL_01893 1.6e-36 yneF S UPF0154 protein
IHMCCOPL_01894 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IHMCCOPL_01895 1.3e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IHMCCOPL_01896 3.9e-98 XK27_09740 S Phosphoesterase
IHMCCOPL_01897 8.3e-87 ykuL S CBS domain
IHMCCOPL_01898 5e-134 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IHMCCOPL_01899 4.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IHMCCOPL_01900 5.9e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IHMCCOPL_01901 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IHMCCOPL_01902 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
IHMCCOPL_01903 4.2e-259 trkH P Cation transport protein
IHMCCOPL_01904 2.2e-246 trkA P Potassium transporter peripheral membrane component
IHMCCOPL_01905 4.4e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IHMCCOPL_01906 1.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IHMCCOPL_01907 4.4e-107 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
IHMCCOPL_01908 1.2e-152 K sequence-specific DNA binding
IHMCCOPL_01909 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IHMCCOPL_01910 1.3e-54 yhaI L Membrane
IHMCCOPL_01911 1.6e-247 S Domain of unknown function (DUF4173)
IHMCCOPL_01912 6.8e-95 ureI S AmiS/UreI family transporter
IHMCCOPL_01913 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IHMCCOPL_01914 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IHMCCOPL_01915 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IHMCCOPL_01916 3.3e-77 ureE O enzyme active site formation
IHMCCOPL_01917 1.7e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IHMCCOPL_01918 6.2e-111 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IHMCCOPL_01919 9.8e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IHMCCOPL_01920 2.1e-177 cbiM P biosynthesis protein CbiM
IHMCCOPL_01921 1.4e-136 P cobalt transport protein
IHMCCOPL_01922 6.3e-131 cbiO P ABC transporter
IHMCCOPL_01923 1.1e-137 ET ABC transporter substrate-binding protein
IHMCCOPL_01924 4.6e-163 metQ M Belongs to the NlpA lipoprotein family
IHMCCOPL_01925 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IHMCCOPL_01926 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IHMCCOPL_01927 8e-99 metI P ABC transporter (Permease
IHMCCOPL_01928 3e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IHMCCOPL_01929 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
IHMCCOPL_01930 8e-94 S UPF0397 protein
IHMCCOPL_01931 1.5e-308 ykoD P abc transporter atp-binding protein
IHMCCOPL_01932 3.5e-149 cbiQ P cobalt transport
IHMCCOPL_01933 2.3e-119 ktrA P COG0569 K transport systems, NAD-binding component
IHMCCOPL_01934 1.9e-237 P COG0168 Trk-type K transport systems, membrane components
IHMCCOPL_01935 2.6e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
IHMCCOPL_01936 4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
IHMCCOPL_01937 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHMCCOPL_01938 5.9e-280 T PhoQ Sensor
IHMCCOPL_01939 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHMCCOPL_01940 1.5e-214 dnaB L Replication initiation and membrane attachment
IHMCCOPL_01941 4.4e-166 dnaI L Primosomal protein DnaI
IHMCCOPL_01942 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IHMCCOPL_01943 2.3e-113
IHMCCOPL_01944 1.4e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IHMCCOPL_01945 2.5e-62 manO S protein conserved in bacteria
IHMCCOPL_01946 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
IHMCCOPL_01947 1.2e-117 manM G pts system
IHMCCOPL_01948 4.9e-174 manL 2.7.1.191 G pts system
IHMCCOPL_01949 2.6e-67 manO S Protein conserved in bacteria
IHMCCOPL_01950 5.9e-158 manN G PTS system mannose fructose sorbose family IID component
IHMCCOPL_01951 8.3e-132 manY G pts system
IHMCCOPL_01952 5.3e-168 manL 2.7.1.191 G pts system
IHMCCOPL_01953 7.1e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
IHMCCOPL_01954 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IHMCCOPL_01955 1.6e-247 pbuO S permease
IHMCCOPL_01956 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
IHMCCOPL_01957 6e-91 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
IHMCCOPL_01958 5.7e-188 brpA K Transcriptional
IHMCCOPL_01959 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
IHMCCOPL_01960 7.1e-196 nusA K Participates in both transcription termination and antitermination
IHMCCOPL_01961 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
IHMCCOPL_01962 1.4e-41 ylxQ J ribosomal protein
IHMCCOPL_01963 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IHMCCOPL_01964 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IHMCCOPL_01965 1.7e-99 yvdD 3.2.2.10 S Belongs to the LOG family
IHMCCOPL_01966 1.7e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHMCCOPL_01967 5.4e-287 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
IHMCCOPL_01968 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
IHMCCOPL_01969 2.6e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
IHMCCOPL_01970 3.4e-219 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IHMCCOPL_01971 1.2e-310 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
IHMCCOPL_01972 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
IHMCCOPL_01973 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IHMCCOPL_01974 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IHMCCOPL_01975 2.4e-72 ylbF S Belongs to the UPF0342 family
IHMCCOPL_01976 1.8e-44 ylbG S UPF0298 protein
IHMCCOPL_01977 5.7e-206 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IHMCCOPL_01978 2.1e-144 livH E Belongs to the binding-protein-dependent transport system permease family
IHMCCOPL_01979 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
IHMCCOPL_01980 5.3e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IHMCCOPL_01981 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IHMCCOPL_01982 1.6e-112 acuB S CBS domain
IHMCCOPL_01983 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IHMCCOPL_01984 3.5e-109 yvyE 3.4.13.9 S YigZ family
IHMCCOPL_01985 2.7e-249 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IHMCCOPL_01986 8.5e-82 comFC K competence protein
IHMCCOPL_01987 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHMCCOPL_01988 8.1e-92 L Transposase
IHMCCOPL_01989 3e-62 tnp* 1.1.1.193 L An automated process has identified a potential problem with this gene model
IHMCCOPL_01990 5.7e-183 KLT Protein tyrosine kinase
IHMCCOPL_01991 1.2e-217 sip L Belongs to the 'phage' integrase family
IHMCCOPL_01992 2.9e-22 S MerR HTH family regulatory protein
IHMCCOPL_01993 2.3e-105 S Plasmid replication protein
IHMCCOPL_01994 2.6e-45
IHMCCOPL_01995 4.8e-183 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IHMCCOPL_01996 5.8e-44
IHMCCOPL_01998 5.3e-120
IHMCCOPL_01999 1.4e-86 XK26_04895
IHMCCOPL_02000 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IHMCCOPL_02001 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IHMCCOPL_02002 1.9e-219 metE 2.1.1.14 E Methionine synthase
IHMCCOPL_02003 4.5e-206 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IHMCCOPL_02004 5e-240 hisS 6.1.1.21 J histidyl-tRNA synthetase
IHMCCOPL_02006 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IHMCCOPL_02007 9.3e-167 XK27_01785 S cog cog1284
IHMCCOPL_02008 2.4e-122 yaaA S Belongs to the UPF0246 family
IHMCCOPL_02009 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHMCCOPL_02010 2.9e-90 XK27_10930 K acetyltransferase
IHMCCOPL_02011 7.5e-14
IHMCCOPL_02012 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IHMCCOPL_02013 8.3e-296 ccs S the current gene model (or a revised gene model) may contain a frame shift
IHMCCOPL_02014 3.2e-44 yrzB S Belongs to the UPF0473 family
IHMCCOPL_02015 2.3e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IHMCCOPL_02016 6.3e-44 yrzL S Belongs to the UPF0297 family
IHMCCOPL_02017 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IHMCCOPL_02018 3.7e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
IHMCCOPL_02020 1e-212 int L Belongs to the 'phage' integrase family
IHMCCOPL_02021 1.9e-18 S Domain of unknown function (DUF3173)
IHMCCOPL_02022 3.8e-155 L Replication initiation factor
IHMCCOPL_02023 3.8e-90 K Cro/C1-type HTH DNA-binding domain
IHMCCOPL_02024 1.1e-173 yeiH S membrane
IHMCCOPL_02026 1.4e-92 adk 2.7.4.3 F topology modulation protein
IHMCCOPL_02027 1.1e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IHMCCOPL_02028 4.9e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IHMCCOPL_02029 9.7e-36 XK27_09805 S MORN repeat protein
IHMCCOPL_02030 0.0 XK27_09800 I Acyltransferase
IHMCCOPL_02031 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IHMCCOPL_02032 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
IHMCCOPL_02033 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IHMCCOPL_02034 1.7e-103 rplD J Forms part of the polypeptide exit tunnel
IHMCCOPL_02035 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IHMCCOPL_02036 1.5e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IHMCCOPL_02037 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IHMCCOPL_02038 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IHMCCOPL_02039 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IHMCCOPL_02040 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IHMCCOPL_02041 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
IHMCCOPL_02042 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IHMCCOPL_02043 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IHMCCOPL_02044 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IHMCCOPL_02045 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IHMCCOPL_02046 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IHMCCOPL_02047 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IHMCCOPL_02048 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IHMCCOPL_02049 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IHMCCOPL_02050 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IHMCCOPL_02051 1.9e-23 rpmD J ribosomal protein l30
IHMCCOPL_02052 5.7e-58 rplO J binds to the 23S rRNA
IHMCCOPL_02053 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IHMCCOPL_02054 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IHMCCOPL_02055 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IHMCCOPL_02056 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IHMCCOPL_02057 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IHMCCOPL_02058 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IHMCCOPL_02059 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHMCCOPL_02060 4.4e-62 rplQ J ribosomal protein l17
IHMCCOPL_02061 4.6e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
IHMCCOPL_02063 3.1e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
IHMCCOPL_02065 2.2e-94 ywlG S Belongs to the UPF0340 family
IHMCCOPL_02066 3.9e-125 treR K trehalose operon
IHMCCOPL_02067 1.2e-288 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
IHMCCOPL_02068 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IHMCCOPL_02069 0.0 pepO 3.4.24.71 O Peptidase family M13
IHMCCOPL_02070 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IHMCCOPL_02073 5.1e-276 thrC 4.2.3.1 E Threonine synthase
IHMCCOPL_02074 8.7e-224 norN V Mate efflux family protein
IHMCCOPL_02075 1.4e-57 asp S cog cog1302
IHMCCOPL_02076 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
IHMCCOPL_02077 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IHMCCOPL_02078 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
IHMCCOPL_02079 2.5e-75 ilvN 2.2.1.6 E Acetolactate synthase
IHMCCOPL_02080 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IHMCCOPL_02081 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IHMCCOPL_02082 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IHMCCOPL_02083 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHMCCOPL_02084 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHMCCOPL_02085 1e-68 S cog cog4699
IHMCCOPL_02086 3.5e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IHMCCOPL_02087 1.2e-141 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IHMCCOPL_02088 2.2e-43 comGC U Required for transformation and DNA binding
IHMCCOPL_02089 8.4e-70 cglD NU Competence protein
IHMCCOPL_02090 5.3e-15 NU Type II secretory pathway pseudopilin
IHMCCOPL_02091 5.8e-71 comGF U Competence protein ComGF
IHMCCOPL_02092 1.2e-12 comGF U Putative Competence protein ComGF
IHMCCOPL_02093 5e-176 ytxK 2.1.1.72 L DNA methylase
IHMCCOPL_02094 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHMCCOPL_02095 1.3e-25 lanR K sequence-specific DNA binding
IHMCCOPL_02096 3.4e-107 V CAAX protease self-immunity
IHMCCOPL_02097 0.0 M Pilin isopeptide linkage domain protein
IHMCCOPL_02098 8.5e-115 M domain protein
IHMCCOPL_02099 5.4e-194 V ABC transporter (Permease
IHMCCOPL_02100 5.6e-124 V abc transporter atp-binding protein
IHMCCOPL_02101 6.7e-93 tetR K transcriptional regulator
IHMCCOPL_02102 1.3e-118 GM domain, Protein
IHMCCOPL_02103 1.7e-237 bipA S protein secretion
IHMCCOPL_02104 3.4e-119 M Pilin isopeptide linkage domain protein
IHMCCOPL_02105 3e-87 L COG3547 Transposase and inactivated derivatives
IHMCCOPL_02106 2.2e-114 L COG3547 Transposase and inactivated derivatives
IHMCCOPL_02107 1.3e-26 bipA S protein secretion

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)