ORF_ID e_value Gene_name EC_number CAZy COGs Description
HKIJACJP_00001 2e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HKIJACJP_00002 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HKIJACJP_00003 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
HKIJACJP_00004 4.9e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HKIJACJP_00005 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
HKIJACJP_00006 3.9e-240 hemL 5.4.3.8 H Aminotransferase class-III
HKIJACJP_00007 2.8e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
HKIJACJP_00008 2.6e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HKIJACJP_00009 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HKIJACJP_00010 7e-59 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
HKIJACJP_00011 2.7e-240 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HKIJACJP_00012 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
HKIJACJP_00013 6.8e-103 cbiQ P Cobalt transport protein
HKIJACJP_00014 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HKIJACJP_00015 1e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HKIJACJP_00016 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HKIJACJP_00017 1.8e-107 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
HKIJACJP_00018 4.6e-178 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HKIJACJP_00019 2.5e-98 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
HKIJACJP_00020 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HKIJACJP_00021 3.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
HKIJACJP_00022 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HKIJACJP_00023 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HKIJACJP_00024 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HKIJACJP_00025 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HKIJACJP_00026 2.5e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
HKIJACJP_00027 4.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HKIJACJP_00028 8.1e-204 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HKIJACJP_00029 1.8e-169 cobD 4.1.1.81 E Aminotransferase class I and II
HKIJACJP_00030 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
HKIJACJP_00031 2.7e-117 XK27_04590 S NADPH-dependent FMN reductase
HKIJACJP_00032 2.2e-73 fld C Flavodoxin
HKIJACJP_00033 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
HKIJACJP_00034 5.9e-68 P Cadmium resistance transporter
HKIJACJP_00035 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
HKIJACJP_00036 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
HKIJACJP_00037 1.1e-53 pduU E BMC
HKIJACJP_00038 1.9e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKIJACJP_00039 2.1e-202 pduQ C Iron-containing alcohol dehydrogenase
HKIJACJP_00040 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HKIJACJP_00041 4.5e-77 pduO S Haem-degrading
HKIJACJP_00042 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HKIJACJP_00043 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HKIJACJP_00044 1.3e-79 S Putative propanediol utilisation
HKIJACJP_00045 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HKIJACJP_00046 7.8e-40 pduA_4 CQ BMC
HKIJACJP_00047 1.8e-56 pduK CQ BMC
HKIJACJP_00048 2.6e-45 pduH S Dehydratase medium subunit
HKIJACJP_00049 9.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
HKIJACJP_00050 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
HKIJACJP_00051 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HKIJACJP_00052 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HKIJACJP_00053 2.7e-134 pduB E BMC
HKIJACJP_00054 1.6e-37 pduA_4 CQ BMC
HKIJACJP_00055 8.3e-159 K helix_turn_helix, arabinose operon control protein
HKIJACJP_00056 3.6e-138 eutJ E Hsp70 protein
HKIJACJP_00057 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HKIJACJP_00058 2.2e-160
HKIJACJP_00059 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HKIJACJP_00060 2.6e-160 S AI-2E family transporter
HKIJACJP_00061 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
HKIJACJP_00062 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
HKIJACJP_00063 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
HKIJACJP_00064 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
HKIJACJP_00065 1.4e-153 ypdB V (ABC) transporter
HKIJACJP_00066 1.6e-236 yhdP S Transporter associated domain
HKIJACJP_00067 2.7e-82 nrdI F Belongs to the NrdI family
HKIJACJP_00068 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
HKIJACJP_00069 4.4e-190 yeaN P Transporter, major facilitator family protein
HKIJACJP_00070 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKIJACJP_00071 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKIJACJP_00072 2.3e-28
HKIJACJP_00073 0.0 lacS G Transporter
HKIJACJP_00074 1.4e-68 L SNF2 family N-terminal domain
HKIJACJP_00075 1.6e-82
HKIJACJP_00076 2.7e-72 V HNH nucleases
HKIJACJP_00077 5.7e-92
HKIJACJP_00078 4.4e-201 2.1.1.72 KL DNA methylase
HKIJACJP_00079 6e-53 S Psort location Cytoplasmic, score
HKIJACJP_00080 1.1e-24 S Domain of unknown function (DUF5049)
HKIJACJP_00081 1.5e-289 S overlaps another CDS with the same product name
HKIJACJP_00084 2.8e-11 K Antidote-toxin recognition MazE, bacterial antitoxin
HKIJACJP_00085 1.3e-216 S Phage portal protein
HKIJACJP_00086 1e-71 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HKIJACJP_00087 7.1e-172 S Phage capsid family
HKIJACJP_00088 2.2e-31 S Phage gp6-like head-tail connector protein
HKIJACJP_00089 1.9e-46 S Phage head-tail joining protein
HKIJACJP_00090 4.5e-52 S Bacteriophage holin family
HKIJACJP_00092 7.7e-118 L Recombinase zinc beta ribbon domain
HKIJACJP_00093 1.2e-14 S Recombinase
HKIJACJP_00094 3.8e-197 L Recombinase
HKIJACJP_00096 4.5e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKIJACJP_00097 8.7e-187 yegS 2.7.1.107 G Lipid kinase
HKIJACJP_00098 9.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKIJACJP_00099 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKIJACJP_00100 5.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKIJACJP_00101 1.8e-201 camS S sex pheromone
HKIJACJP_00102 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKIJACJP_00103 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HKIJACJP_00104 1.1e-209 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKIJACJP_00105 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKIJACJP_00106 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
HKIJACJP_00107 8e-140 IQ reductase
HKIJACJP_00108 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HKIJACJP_00109 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKIJACJP_00110 4.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKIJACJP_00111 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKIJACJP_00112 8e-149 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKIJACJP_00113 3.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKIJACJP_00114 1.1e-62 rplQ J Ribosomal protein L17
HKIJACJP_00115 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKIJACJP_00116 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKIJACJP_00117 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKIJACJP_00118 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HKIJACJP_00119 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKIJACJP_00120 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKIJACJP_00121 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKIJACJP_00122 1.3e-62 rplO J Binds to the 23S rRNA
HKIJACJP_00123 2.9e-24 rpmD J Ribosomal protein L30
HKIJACJP_00124 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKIJACJP_00125 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKIJACJP_00126 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKIJACJP_00127 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKIJACJP_00128 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKIJACJP_00129 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKIJACJP_00130 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKIJACJP_00131 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKIJACJP_00132 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKIJACJP_00133 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HKIJACJP_00134 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKIJACJP_00135 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKIJACJP_00136 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKIJACJP_00137 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKIJACJP_00138 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKIJACJP_00139 4.9e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKIJACJP_00140 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HKIJACJP_00141 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKIJACJP_00142 3.2e-47 rpsJ J Involved in the binding of tRNA to the ribosomes
HKIJACJP_00143 3.9e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HKIJACJP_00144 1.1e-218 EG GntP family permease
HKIJACJP_00145 8.5e-84 KT Putative sugar diacid recognition
HKIJACJP_00146 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKIJACJP_00147 7.7e-219 patA 2.6.1.1 E Aminotransferase
HKIJACJP_00148 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKIJACJP_00149 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKIJACJP_00150 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKIJACJP_00151 2.4e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKIJACJP_00152 4.1e-245 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKIJACJP_00153 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HKIJACJP_00154 1.1e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKIJACJP_00155 5.8e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKIJACJP_00156 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKIJACJP_00157 1.3e-117 S Repeat protein
HKIJACJP_00158 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HKIJACJP_00159 5.3e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKIJACJP_00160 7.5e-58 XK27_04120 S Putative amino acid metabolism
HKIJACJP_00161 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
HKIJACJP_00162 5.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKIJACJP_00164 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HKIJACJP_00165 4.2e-32 cspA K Cold shock protein
HKIJACJP_00166 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKIJACJP_00167 1e-35 divIVA D DivIVA domain protein
HKIJACJP_00168 5.4e-144 ylmH S S4 domain protein
HKIJACJP_00169 8.3e-41 yggT S YGGT family
HKIJACJP_00170 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKIJACJP_00171 7.8e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKIJACJP_00172 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKIJACJP_00173 7.9e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKIJACJP_00174 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKIJACJP_00175 1.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKIJACJP_00176 4.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKIJACJP_00177 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HKIJACJP_00178 1.3e-55 ftsL D Cell division protein FtsL
HKIJACJP_00179 1.3e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKIJACJP_00180 3.1e-77 mraZ K Belongs to the MraZ family
HKIJACJP_00181 1.9e-56
HKIJACJP_00182 1.2e-10 S Protein of unknown function (DUF4044)
HKIJACJP_00183 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HKIJACJP_00184 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKIJACJP_00185 1e-159 rrmA 2.1.1.187 H Methyltransferase
HKIJACJP_00186 6.6e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HKIJACJP_00187 5e-75 osmC O OsmC-like protein
HKIJACJP_00188 3.2e-173 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKIJACJP_00189 1.2e-214 patA 2.6.1.1 E Aminotransferase
HKIJACJP_00190 7.8e-32
HKIJACJP_00191 0.0 clpL O associated with various cellular activities
HKIJACJP_00193 2e-103 wecD3 K PFAM GCN5-related N-acetyltransferase
HKIJACJP_00194 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKIJACJP_00195 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKIJACJP_00196 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HKIJACJP_00197 4.3e-172 malR K Transcriptional regulator, LacI family
HKIJACJP_00198 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
HKIJACJP_00199 1.1e-256 malT G Major Facilitator
HKIJACJP_00200 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HKIJACJP_00201 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HKIJACJP_00202 1e-71
HKIJACJP_00203 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
HKIJACJP_00204 3.3e-118 K response regulator
HKIJACJP_00205 3.1e-226 sptS 2.7.13.3 T Histidine kinase
HKIJACJP_00206 1.4e-215 yfeO P Voltage gated chloride channel
HKIJACJP_00207 1.6e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HKIJACJP_00208 6.6e-136 puuD S peptidase C26
HKIJACJP_00209 5.9e-168 yvgN C Aldo keto reductase
HKIJACJP_00210 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HKIJACJP_00211 3e-87 hmpT S ECF-type riboflavin transporter, S component
HKIJACJP_00212 1.7e-262 nox C NADH oxidase
HKIJACJP_00213 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKIJACJP_00214 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKIJACJP_00215 6.9e-83
HKIJACJP_00216 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKIJACJP_00218 1.4e-13 steT_1 E amino acid
HKIJACJP_00219 2.1e-12 K Transcriptional regulator, TetR family
HKIJACJP_00220 3.4e-74 K Transcriptional regulator, TetR family
HKIJACJP_00221 1.5e-91 2.3.1.183 M Acetyltransferase GNAT family
HKIJACJP_00222 2.2e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HKIJACJP_00223 3.2e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
HKIJACJP_00224 5.8e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKIJACJP_00225 0.0 asnB 6.3.5.4 E Asparagine synthase
HKIJACJP_00226 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKIJACJP_00227 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKIJACJP_00228 6.3e-129 jag S R3H domain protein
HKIJACJP_00229 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKIJACJP_00230 6e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKIJACJP_00231 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HKIJACJP_00232 5.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKIJACJP_00233 2e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKIJACJP_00234 3.8e-34 yaaA S S4 domain protein YaaA
HKIJACJP_00235 6.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKIJACJP_00236 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKIJACJP_00237 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKIJACJP_00238 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HKIJACJP_00239 2.8e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKIJACJP_00240 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKIJACJP_00241 2.4e-74 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKIJACJP_00242 2.6e-100 deoR K sugar-binding domain protein
HKIJACJP_00243 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HKIJACJP_00244 2e-74 rplI J Binds to the 23S rRNA
HKIJACJP_00245 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HKIJACJP_00246 9e-207 yttB EGP Major facilitator Superfamily
HKIJACJP_00247 9.1e-61
HKIJACJP_00248 6.9e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HKIJACJP_00250 7.5e-96 Z012_01130 S Fic/DOC family
HKIJACJP_00252 6.8e-72 K helix_turn_helix multiple antibiotic resistance protein
HKIJACJP_00253 7.6e-308 lmrA 3.6.3.44 V ABC transporter
HKIJACJP_00255 3.1e-130 K response regulator
HKIJACJP_00256 0.0 vicK 2.7.13.3 T Histidine kinase
HKIJACJP_00257 2.4e-245 yycH S YycH protein
HKIJACJP_00258 7.8e-149 yycI S YycH protein
HKIJACJP_00259 2.3e-153 vicX 3.1.26.11 S domain protein
HKIJACJP_00260 1.6e-214 htrA 3.4.21.107 O serine protease
HKIJACJP_00261 9e-83 L transposase IS116 IS110 IS902 family protein
HKIJACJP_00262 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HKIJACJP_00263 9e-53 ysxB J Cysteine protease Prp
HKIJACJP_00264 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HKIJACJP_00265 2.6e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKIJACJP_00266 1.5e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HKIJACJP_00267 6.6e-114 J 2'-5' RNA ligase superfamily
HKIJACJP_00268 6.4e-70 yqhY S Asp23 family, cell envelope-related function
HKIJACJP_00269 8e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKIJACJP_00270 4e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKIJACJP_00271 6.5e-214 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKIJACJP_00272 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKIJACJP_00273 5.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKIJACJP_00274 3.4e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HKIJACJP_00275 1.6e-76 argR K Regulates arginine biosynthesis genes
HKIJACJP_00276 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
HKIJACJP_00277 2.1e-52
HKIJACJP_00278 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HKIJACJP_00279 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKIJACJP_00280 7.4e-209 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKIJACJP_00281 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKIJACJP_00282 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKIJACJP_00283 2.4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKIJACJP_00284 6.1e-129 stp 3.1.3.16 T phosphatase
HKIJACJP_00285 0.0 KLT serine threonine protein kinase
HKIJACJP_00286 1.2e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKIJACJP_00287 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HKIJACJP_00288 3.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
HKIJACJP_00289 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HKIJACJP_00290 4.7e-58 asp S Asp23 family, cell envelope-related function
HKIJACJP_00291 0.0 yloV S DAK2 domain fusion protein YloV
HKIJACJP_00292 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKIJACJP_00293 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKIJACJP_00294 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKIJACJP_00295 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKIJACJP_00296 0.0 smc D Required for chromosome condensation and partitioning
HKIJACJP_00297 1.9e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKIJACJP_00298 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKIJACJP_00299 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKIJACJP_00300 6.5e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HKIJACJP_00301 7e-40 ylqC S Belongs to the UPF0109 family
HKIJACJP_00302 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKIJACJP_00303 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HKIJACJP_00304 2.5e-161 yfnA E amino acid
HKIJACJP_00305 2e-80 yfnA E amino acid
HKIJACJP_00306 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HKIJACJP_00307 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKIJACJP_00308 3.2e-101 ypsA S Belongs to the UPF0398 family
HKIJACJP_00309 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKIJACJP_00310 3e-81 F Belongs to the NrdI family
HKIJACJP_00311 1.1e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HKIJACJP_00312 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
HKIJACJP_00313 1.5e-65 esbA S Family of unknown function (DUF5322)
HKIJACJP_00314 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKIJACJP_00315 2.9e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKIJACJP_00316 3.6e-207 carA 6.3.5.5 F Belongs to the CarA family
HKIJACJP_00317 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HKIJACJP_00318 0.0 FbpA K Fibronectin-binding protein
HKIJACJP_00319 3.8e-108 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKIJACJP_00320 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKIJACJP_00321 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKIJACJP_00322 7.5e-158 htpX O Belongs to the peptidase M48B family
HKIJACJP_00323 7e-93 lemA S LemA family
HKIJACJP_00324 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKIJACJP_00325 2.7e-120 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HKIJACJP_00326 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HKIJACJP_00327 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKIJACJP_00328 8.8e-158 3.2.1.55 GH51 G Right handed beta helix region
HKIJACJP_00329 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HKIJACJP_00330 7.3e-116 srtA 3.4.22.70 M sortase family
HKIJACJP_00331 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HKIJACJP_00332 5.4e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKIJACJP_00333 4.6e-41 rpmE2 J Ribosomal protein L31
HKIJACJP_00334 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKIJACJP_00335 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKIJACJP_00336 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKIJACJP_00337 5.2e-53 ywiB S Domain of unknown function (DUF1934)
HKIJACJP_00338 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HKIJACJP_00339 6.6e-174 K AI-2E family transporter
HKIJACJP_00340 1.2e-227 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HKIJACJP_00341 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKIJACJP_00342 1.4e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HKIJACJP_00343 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKIJACJP_00344 5.1e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKIJACJP_00345 1.9e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKIJACJP_00346 7.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKIJACJP_00347 1.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HKIJACJP_00348 5.3e-132 K LysR substrate binding domain
HKIJACJP_00349 1.6e-52 azlD S branched-chain amino acid
HKIJACJP_00350 2.7e-139 azlC E AzlC protein
HKIJACJP_00351 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
HKIJACJP_00352 3.8e-125 K response regulator
HKIJACJP_00353 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKIJACJP_00354 4e-170 deoR K sugar-binding domain protein
HKIJACJP_00355 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HKIJACJP_00356 3.2e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HKIJACJP_00357 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKIJACJP_00358 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKIJACJP_00359 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
HKIJACJP_00360 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKIJACJP_00361 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
HKIJACJP_00362 5e-154 spo0J K Belongs to the ParB family
HKIJACJP_00363 3.6e-140 soj D Sporulation initiation inhibitor
HKIJACJP_00364 1.5e-143 noc K Belongs to the ParB family
HKIJACJP_00365 3.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HKIJACJP_00366 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HKIJACJP_00367 6.6e-170 rihC 3.2.2.1 F Nucleoside
HKIJACJP_00368 1.3e-218 nupG F Nucleoside transporter
HKIJACJP_00369 1.6e-220 cycA E Amino acid permease
HKIJACJP_00370 1.9e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKIJACJP_00371 2.2e-263 glnP P ABC transporter
HKIJACJP_00372 7.1e-304 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKIJACJP_00373 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKIJACJP_00374 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKIJACJP_00375 2.8e-38 S Protein of unknown function (DUF2508)
HKIJACJP_00376 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKIJACJP_00377 2.9e-51 yaaQ S Cyclic-di-AMP receptor
HKIJACJP_00378 2.5e-181 holB 2.7.7.7 L DNA polymerase III
HKIJACJP_00379 3.1e-43 yabA L Involved in initiation control of chromosome replication
HKIJACJP_00380 1.9e-153 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKIJACJP_00381 3.8e-134 fat 3.1.2.21 I Acyl-ACP thioesterase
HKIJACJP_00382 7e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKIJACJP_00383 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKIJACJP_00384 6.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKIJACJP_00385 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKIJACJP_00386 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HKIJACJP_00387 2.9e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HKIJACJP_00388 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKIJACJP_00389 8e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKIJACJP_00390 3.8e-216 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKIJACJP_00391 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKIJACJP_00392 3.6e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HKIJACJP_00393 1.3e-226 mtnE 2.6.1.83 E Aminotransferase
HKIJACJP_00394 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKIJACJP_00395 0.0 uup S ABC transporter, ATP-binding protein
HKIJACJP_00396 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKIJACJP_00398 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKIJACJP_00399 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKIJACJP_00400 1.3e-79 S Aminoacyl-tRNA editing domain
HKIJACJP_00401 1.3e-301 ybeC E amino acid
HKIJACJP_00402 0.0 ydaO E amino acid
HKIJACJP_00403 2.7e-39
HKIJACJP_00404 6.2e-67 rmaI K Transcriptional regulator
HKIJACJP_00405 6.1e-153 EGP Major facilitator Superfamily
HKIJACJP_00406 1.3e-36 EGP Major facilitator Superfamily
HKIJACJP_00407 2.3e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HKIJACJP_00408 2.2e-21
HKIJACJP_00409 1.3e-262 S Uncharacterized protein conserved in bacteria (DUF2252)
HKIJACJP_00410 1.1e-169 L transposase, IS605 OrfB family
HKIJACJP_00412 7.8e-32 L PFAM plasmid pRiA4b ORF-3 family protein
HKIJACJP_00413 3.8e-226 L PFAM plasmid pRiA4b ORF-3 family protein
HKIJACJP_00414 9.6e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HKIJACJP_00415 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKIJACJP_00416 4.3e-158 mleR K LysR family
HKIJACJP_00417 8.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HKIJACJP_00418 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKIJACJP_00419 4.5e-266 frdC 1.3.5.4 C FAD binding domain
HKIJACJP_00420 3.5e-129 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKIJACJP_00421 9.3e-203 P Sodium:sulfate symporter transmembrane region
HKIJACJP_00422 1.4e-125 citR K sugar-binding domain protein
HKIJACJP_00423 6.1e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HKIJACJP_00424 1.7e-148 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKIJACJP_00425 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
HKIJACJP_00426 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HKIJACJP_00427 7.1e-273 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HKIJACJP_00428 3.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKIJACJP_00429 3.8e-113 ydjP I Alpha/beta hydrolase family
HKIJACJP_00430 1.1e-158 mleR K LysR family
HKIJACJP_00431 9.4e-253 yjjP S Putative threonine/serine exporter
HKIJACJP_00432 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
HKIJACJP_00433 6.5e-271 emrY EGP Major facilitator Superfamily
HKIJACJP_00434 2.7e-185 I Alpha beta
HKIJACJP_00435 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HKIJACJP_00436 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKIJACJP_00437 1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKIJACJP_00438 1.3e-210 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HKIJACJP_00439 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKIJACJP_00440 1.3e-35 ynzC S UPF0291 protein
HKIJACJP_00441 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HKIJACJP_00442 1.6e-117 plsC 2.3.1.51 I Acyltransferase
HKIJACJP_00443 3.5e-140 yabB 2.1.1.223 L Methyltransferase small domain
HKIJACJP_00444 7.1e-49 yazA L GIY-YIG catalytic domain protein
HKIJACJP_00445 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKIJACJP_00446 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HKIJACJP_00447 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKIJACJP_00448 8.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HKIJACJP_00449 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKIJACJP_00450 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKIJACJP_00451 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
HKIJACJP_00452 4.1e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HKIJACJP_00453 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKIJACJP_00454 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKIJACJP_00455 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
HKIJACJP_00456 1.4e-215 nusA K Participates in both transcription termination and antitermination
HKIJACJP_00457 1e-44 ylxR K Protein of unknown function (DUF448)
HKIJACJP_00458 1.3e-48 ylxQ J ribosomal protein
HKIJACJP_00459 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKIJACJP_00460 6.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKIJACJP_00461 2.7e-163 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKIJACJP_00462 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HKIJACJP_00463 2.9e-63
HKIJACJP_00464 1e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKIJACJP_00465 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKIJACJP_00466 0.0 dnaK O Heat shock 70 kDa protein
HKIJACJP_00467 9.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKIJACJP_00468 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKIJACJP_00469 3e-306 S overlaps another CDS with the same product name
HKIJACJP_00470 6.3e-243 S Phage portal protein
HKIJACJP_00471 1.4e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HKIJACJP_00472 2.8e-221 S Phage capsid family
HKIJACJP_00473 4.3e-43 S Phage gp6-like head-tail connector protein
HKIJACJP_00474 6.9e-68 S Phage head-tail joining protein
HKIJACJP_00475 3.6e-70 S Bacteriophage holin family
HKIJACJP_00476 1.2e-20 M Glycosyl hydrolases family 25
HKIJACJP_00477 3.8e-69 M Glycosyl hydrolases family 25
HKIJACJP_00478 4.7e-27
HKIJACJP_00479 2.1e-283 L Recombinase zinc beta ribbon domain
HKIJACJP_00480 9.1e-284 L Recombinase
HKIJACJP_00481 1.7e-127 cylA V ABC transporter
HKIJACJP_00482 3e-124 cylB V ABC-2 type transporter
HKIJACJP_00483 2.2e-65 K LytTr DNA-binding domain
HKIJACJP_00484 1.7e-37 S Protein of unknown function (DUF3021)
HKIJACJP_00487 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HKIJACJP_00488 4.2e-52 3.1.21.3 V Type I restriction
HKIJACJP_00489 1.9e-175 xerC L Belongs to the 'phage' integrase family
HKIJACJP_00490 5.2e-39 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HKIJACJP_00491 6.4e-32 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HKIJACJP_00492 2.2e-290 2.1.1.72 V type I restriction-modification system
HKIJACJP_00493 3.9e-23 K Cro/C1-type HTH DNA-binding domain
HKIJACJP_00494 6.7e-122 F helicase superfamily c-terminal domain
HKIJACJP_00495 7.2e-16 S Domain of unknown function (DUF1837)
HKIJACJP_00497 1.1e-22
HKIJACJP_00498 1.6e-28
HKIJACJP_00499 9.1e-201 L Protein of unknown function (DUF2800)
HKIJACJP_00500 9.5e-95 S Protein of unknown function (DUF2815)
HKIJACJP_00501 1.2e-102 pncA Q Isochorismatase family
HKIJACJP_00502 6.6e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKIJACJP_00503 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
HKIJACJP_00504 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKIJACJP_00505 8.8e-172 S Phage capsid family
HKIJACJP_00506 1.3e-39 S Phage gp6-like head-tail connector protein
HKIJACJP_00507 7.2e-54 S Phage head-tail joining protein
HKIJACJP_00508 2.4e-29 S Bacteriophage holin family
HKIJACJP_00509 8.2e-19
HKIJACJP_00510 1.3e-68 L Recombinase zinc beta ribbon domain
HKIJACJP_00511 4.7e-19 L Recombinase zinc beta ribbon domain
HKIJACJP_00512 1.7e-21 L recombinase activity
HKIJACJP_00513 7.6e-67 L Recombinase
HKIJACJP_00514 1.5e-69 L Recombinase
HKIJACJP_00515 2e-22 5.1.1.13 M Asp/Glu/Hydantoin racemase
HKIJACJP_00516 3.6e-62 5.1.1.13 M Asp/Glu/Hydantoin racemase
HKIJACJP_00517 6.3e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
HKIJACJP_00518 5.2e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HKIJACJP_00519 1.2e-94 dps P Belongs to the Dps family
HKIJACJP_00520 7.9e-35 copZ C Heavy-metal-associated domain
HKIJACJP_00521 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HKIJACJP_00522 2e-163 L PFAM Integrase catalytic region
HKIJACJP_00523 1.8e-55 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKIJACJP_00525 4.9e-207 L helicase activity
HKIJACJP_00526 1e-120 L helicase activity
HKIJACJP_00527 3.3e-71 K DNA binding
HKIJACJP_00528 1e-88 L Recombinase
HKIJACJP_00529 3.5e-174 S Domain of unknown function (DUF389)
HKIJACJP_00530 5.3e-54 U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKIJACJP_00531 8.1e-07
HKIJACJP_00532 5.8e-288 S Protein of unknown function DUF262
HKIJACJP_00533 0.0 L Type III restriction enzyme, res subunit
HKIJACJP_00534 1.9e-86 2.1.1.72, 3.1.21.4 L site-specific DNA-methyltransferase (adenine-specific) activity
HKIJACJP_00535 5.7e-231 EGP Sugar (and other) transporter
HKIJACJP_00536 1e-254 yfnA E Amino Acid
HKIJACJP_00537 4.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HKIJACJP_00538 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
HKIJACJP_00539 9.6e-82 zur P Belongs to the Fur family
HKIJACJP_00540 4e-17 3.2.1.14 GH18
HKIJACJP_00541 7.1e-150
HKIJACJP_00542 1.7e-38 pspC KT positive regulation of macromolecule biosynthetic process
HKIJACJP_00543 1.7e-93 K Transcriptional regulator (TetR family)
HKIJACJP_00544 1.7e-219 V domain protein
HKIJACJP_00545 2.1e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKIJACJP_00547 6.6e-35 S Transglycosylase associated protein
HKIJACJP_00548 8.6e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKIJACJP_00549 5e-127 3.1.3.73 G phosphoglycerate mutase
HKIJACJP_00550 2.8e-114 dedA S SNARE associated Golgi protein
HKIJACJP_00551 0.0 helD 3.6.4.12 L DNA helicase
HKIJACJP_00552 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
HKIJACJP_00553 6.2e-157 EG EamA-like transporter family
HKIJACJP_00554 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKIJACJP_00555 3.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HKIJACJP_00556 1.3e-218 S cog cog1373
HKIJACJP_00558 4e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HKIJACJP_00563 1.5e-80 C Flavodoxin
HKIJACJP_00564 4.9e-76 yphH S Cupin domain
HKIJACJP_00565 1.1e-72 yeaL S UPF0756 membrane protein
HKIJACJP_00566 1.3e-241 EGP Major facilitator Superfamily
HKIJACJP_00567 5.5e-74 copY K Copper transport repressor CopY TcrY
HKIJACJP_00568 7.2e-245 yhdP S Transporter associated domain
HKIJACJP_00569 0.0 ubiB S ABC1 family
HKIJACJP_00570 1.1e-144 S DUF218 domain
HKIJACJP_00571 5.4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKIJACJP_00572 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKIJACJP_00573 5.9e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKIJACJP_00574 0.0 uvrA3 L excinuclease ABC, A subunit
HKIJACJP_00575 4.3e-121 S SNARE associated Golgi protein
HKIJACJP_00576 2.3e-229 N Uncharacterized conserved protein (DUF2075)
HKIJACJP_00577 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKIJACJP_00579 6.6e-254 yifK E Amino acid permease
HKIJACJP_00580 1.6e-157 endA V DNA/RNA non-specific endonuclease
HKIJACJP_00581 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKIJACJP_00582 2.3e-41 ybaN S Protein of unknown function (DUF454)
HKIJACJP_00583 7e-72 S Protein of unknown function (DUF3290)
HKIJACJP_00584 6.2e-114 yviA S Protein of unknown function (DUF421)
HKIJACJP_00585 2.6e-163 S Alpha/beta hydrolase of unknown function (DUF915)
HKIJACJP_00586 2e-18
HKIJACJP_00587 2.1e-90 ntd 2.4.2.6 F Nucleoside
HKIJACJP_00588 9.6e-152 3.1.3.102, 3.1.3.104 S hydrolase
HKIJACJP_00589 8.9e-41 yrvD S Pfam:DUF1049
HKIJACJP_00591 4.3e-35 S Phage derived protein Gp49-like (DUF891)
HKIJACJP_00592 8.5e-20 K Helix-turn-helix XRE-family like proteins
HKIJACJP_00593 4e-79 I alpha/beta hydrolase fold
HKIJACJP_00594 5.4e-181 galR K Transcriptional regulator
HKIJACJP_00595 3.1e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HKIJACJP_00596 2.5e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKIJACJP_00597 4.1e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HKIJACJP_00598 1.9e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
HKIJACJP_00599 1.5e-91 yxkA S Phosphatidylethanolamine-binding protein
HKIJACJP_00600 9.1e-36
HKIJACJP_00601 2e-52
HKIJACJP_00602 5.3e-201
HKIJACJP_00603 1.2e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKIJACJP_00604 2.9e-134 pnuC H nicotinamide mononucleotide transporter
HKIJACJP_00605 3.9e-156 ytbE 1.1.1.346 S Aldo keto reductase
HKIJACJP_00606 1.9e-124 K response regulator
HKIJACJP_00607 2.8e-182 T PhoQ Sensor
HKIJACJP_00608 4.9e-134 macB2 V ABC transporter, ATP-binding protein
HKIJACJP_00609 0.0 ysaB V FtsX-like permease family
HKIJACJP_00610 5.9e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HKIJACJP_00611 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKIJACJP_00612 8e-54 K helix_turn_helix, mercury resistance
HKIJACJP_00613 2.3e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKIJACJP_00614 3.8e-194 EGP Major facilitator Superfamily
HKIJACJP_00615 3.9e-87 ymdB S Macro domain protein
HKIJACJP_00616 1.4e-105 K Helix-turn-helix XRE-family like proteins
HKIJACJP_00617 0.0 pepO 3.4.24.71 O Peptidase family M13
HKIJACJP_00618 1.9e-46
HKIJACJP_00619 9.6e-231 S Putative metallopeptidase domain
HKIJACJP_00620 4.4e-203 3.1.3.1 S associated with various cellular activities
HKIJACJP_00621 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HKIJACJP_00622 5.9e-64 yeaO S Protein of unknown function, DUF488
HKIJACJP_00623 4.9e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
HKIJACJP_00624 1.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKIJACJP_00625 1.1e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKIJACJP_00626 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HKIJACJP_00627 8.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKIJACJP_00629 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKIJACJP_00630 3.4e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKIJACJP_00631 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
HKIJACJP_00632 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HKIJACJP_00633 2.3e-242 codA 3.5.4.1 F cytosine deaminase
HKIJACJP_00634 6.4e-145 tesE Q hydratase
HKIJACJP_00635 6.9e-113 S (CBS) domain
HKIJACJP_00636 1.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKIJACJP_00637 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKIJACJP_00638 6.2e-39 yabO J S4 domain protein
HKIJACJP_00639 8.1e-55 divIC D Septum formation initiator
HKIJACJP_00640 9.8e-67 yabR J RNA binding
HKIJACJP_00641 2.4e-251 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKIJACJP_00642 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKIJACJP_00643 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKIJACJP_00644 1.1e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKIJACJP_00645 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKIJACJP_00646 3.7e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HKIJACJP_00647 5.4e-48 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKIJACJP_00648 1.5e-82 bioY S BioY family
HKIJACJP_00649 1.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKIJACJP_00650 3.2e-181 phoH T phosphate starvation-inducible protein PhoH
HKIJACJP_00651 3.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKIJACJP_00652 2.1e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HKIJACJP_00653 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKIJACJP_00654 3.8e-145 recO L Involved in DNA repair and RecF pathway recombination
HKIJACJP_00655 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HKIJACJP_00656 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HKIJACJP_00657 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKIJACJP_00658 2.9e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKIJACJP_00659 2.4e-220 patA 2.6.1.1 E Aminotransferase
HKIJACJP_00660 6.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HKIJACJP_00661 1.1e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKIJACJP_00662 2.8e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HKIJACJP_00663 2e-29 S Protein of unknown function (DUF2929)
HKIJACJP_00664 0.0 dnaE 2.7.7.7 L DNA polymerase
HKIJACJP_00665 3.6e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HKIJACJP_00666 3.3e-166 cvfB S S1 domain
HKIJACJP_00667 2.9e-162 xerD D recombinase XerD
HKIJACJP_00668 5.3e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKIJACJP_00669 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKIJACJP_00670 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKIJACJP_00671 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKIJACJP_00672 5.5e-101 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKIJACJP_00673 1.5e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKIJACJP_00674 1.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HKIJACJP_00675 1.5e-112
HKIJACJP_00676 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
HKIJACJP_00677 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKIJACJP_00678 7.3e-86 uspA T Belongs to the universal stress protein A family
HKIJACJP_00679 8.1e-276 pepV 3.5.1.18 E dipeptidase PepV
HKIJACJP_00680 5.4e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKIJACJP_00681 1.1e-300 ytgP S Polysaccharide biosynthesis protein
HKIJACJP_00682 7.6e-42
HKIJACJP_00683 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKIJACJP_00684 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKIJACJP_00685 7.9e-94 tag 3.2.2.20 L glycosylase
HKIJACJP_00686 1e-257 EGP Major facilitator Superfamily
HKIJACJP_00687 2.8e-84 perR P Belongs to the Fur family
HKIJACJP_00688 7.7e-231 cycA E Amino acid permease
HKIJACJP_00689 1.7e-102 V VanZ like family
HKIJACJP_00690 1e-23
HKIJACJP_00691 1.6e-54 S Short repeat of unknown function (DUF308)
HKIJACJP_00692 2.5e-77 S Psort location Cytoplasmic, score
HKIJACJP_00693 1.2e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HKIJACJP_00694 3.8e-75 hsp O Belongs to the small heat shock protein (HSP20) family
HKIJACJP_00695 5.3e-153 yeaE S Aldo keto
HKIJACJP_00696 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
HKIJACJP_00697 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HKIJACJP_00698 2.7e-21 xth 3.1.11.2 L exodeoxyribonuclease III
HKIJACJP_00699 4.1e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKIJACJP_00700 1.4e-26 psiE S Phosphate-starvation-inducible E
HKIJACJP_00701 1.2e-97 ydeN S Serine hydrolase
HKIJACJP_00703 1.1e-181 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKIJACJP_00704 1.2e-253 nhaC C Na H antiporter NhaC
HKIJACJP_00705 1.1e-36 S Cytochrome b5-like Heme/Steroid binding domain
HKIJACJP_00706 7.3e-107 ywnB S NAD(P)H-binding
HKIJACJP_00707 1.2e-114 L PFAM Integrase catalytic region
HKIJACJP_00710 3.5e-175 MA20_14895 S Conserved hypothetical protein 698
HKIJACJP_00711 1.9e-145 K LysR substrate binding domain
HKIJACJP_00712 6.4e-96 V VanZ like family
HKIJACJP_00714 6e-26
HKIJACJP_00716 5.2e-146 L Transposase and inactivated derivatives IS30 family
HKIJACJP_00718 8.7e-113 fic S Fic/DOC family
HKIJACJP_00719 2e-129 L Belongs to the 'phage' integrase family
HKIJACJP_00720 4e-19
HKIJACJP_00723 2.2e-153
HKIJACJP_00725 1.6e-76 L Resolvase, N terminal domain
HKIJACJP_00726 2.2e-10 L Resolvase, N terminal domain
HKIJACJP_00727 6.3e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKIJACJP_00729 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HKIJACJP_00730 6.4e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HKIJACJP_00731 6e-108 tdk 2.7.1.21 F thymidine kinase
HKIJACJP_00732 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKIJACJP_00733 6.6e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKIJACJP_00734 4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKIJACJP_00735 1.1e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKIJACJP_00736 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKIJACJP_00737 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKIJACJP_00738 1.7e-191 yibE S overlaps another CDS with the same product name
HKIJACJP_00739 4.4e-130 yibF S overlaps another CDS with the same product name
HKIJACJP_00740 5.9e-233 pyrP F Permease
HKIJACJP_00741 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HKIJACJP_00742 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKIJACJP_00743 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKIJACJP_00744 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKIJACJP_00745 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKIJACJP_00746 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKIJACJP_00747 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKIJACJP_00748 2.9e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HKIJACJP_00749 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HKIJACJP_00750 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKIJACJP_00751 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HKIJACJP_00752 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HKIJACJP_00753 1e-31 S Protein of unknown function (DUF2969)
HKIJACJP_00754 1.1e-220 rodA D Belongs to the SEDS family
HKIJACJP_00755 1.4e-47 gcvH E glycine cleavage
HKIJACJP_00756 6.2e-31 yajC U Preprotein translocase
HKIJACJP_00757 2.2e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKIJACJP_00758 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKIJACJP_00759 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKIJACJP_00760 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKIJACJP_00761 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKIJACJP_00762 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
HKIJACJP_00763 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKIJACJP_00764 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
HKIJACJP_00765 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKIJACJP_00766 1.7e-137 ymfM S Helix-turn-helix domain
HKIJACJP_00767 2.5e-247 ymfH S Peptidase M16
HKIJACJP_00768 8.1e-227 ymfF S Peptidase M16 inactive domain protein
HKIJACJP_00769 1.9e-158 aatB ET ABC transporter substrate-binding protein
HKIJACJP_00770 4.7e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKIJACJP_00771 3.2e-102 glnP P ABC transporter permease
HKIJACJP_00772 8.7e-93 mreD M rod shape-determining protein MreD
HKIJACJP_00773 3.5e-152 mreC M Involved in formation and maintenance of cell shape
HKIJACJP_00774 1.7e-179 mreB D cell shape determining protein MreB
HKIJACJP_00775 8e-122 radC L DNA repair protein
HKIJACJP_00776 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKIJACJP_00778 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HKIJACJP_00779 3.6e-154 KT YcbB domain
HKIJACJP_00780 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKIJACJP_00781 3.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HKIJACJP_00782 4.5e-158 EG EamA-like transporter family
HKIJACJP_00783 2.9e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HKIJACJP_00784 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HKIJACJP_00785 0.0 copA 3.6.3.54 P P-type ATPase
HKIJACJP_00786 1.2e-85
HKIJACJP_00788 2.3e-56
HKIJACJP_00789 1.1e-149 yjcE P Sodium proton antiporter
HKIJACJP_00790 3.3e-78 yjcE P Sodium proton antiporter
HKIJACJP_00792 2e-91
HKIJACJP_00793 1.9e-306 M domain protein
HKIJACJP_00794 5e-158 M domain protein
HKIJACJP_00795 1.5e-244 L Transposase
HKIJACJP_00796 4.1e-19
HKIJACJP_00797 3.5e-183 ampC V Beta-lactamase
HKIJACJP_00798 3.1e-218 arcA 3.5.3.6 E Arginine
HKIJACJP_00799 2.7e-79 argR K Regulates arginine biosynthesis genes
HKIJACJP_00800 3.2e-259 E Arginine ornithine antiporter
HKIJACJP_00801 1.4e-222 arcD U Amino acid permease
HKIJACJP_00802 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HKIJACJP_00803 1.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKIJACJP_00804 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKIJACJP_00805 4.1e-43 yrzL S Belongs to the UPF0297 family
HKIJACJP_00806 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKIJACJP_00807 6.1e-48 yrzB S Belongs to the UPF0473 family
HKIJACJP_00808 1.6e-86 cvpA S Colicin V production protein
HKIJACJP_00809 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKIJACJP_00810 6.1e-54 trxA O Belongs to the thioredoxin family
HKIJACJP_00811 1.6e-97 yslB S Protein of unknown function (DUF2507)
HKIJACJP_00812 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKIJACJP_00813 9.8e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKIJACJP_00814 3.8e-93 S Phosphoesterase
HKIJACJP_00815 1.1e-74 ykuL S (CBS) domain
HKIJACJP_00816 1.8e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HKIJACJP_00817 6.9e-148 ykuT M mechanosensitive ion channel
HKIJACJP_00818 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKIJACJP_00819 4.3e-16
HKIJACJP_00820 1.1e-195 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HKIJACJP_00821 7.1e-181 ccpA K catabolite control protein A
HKIJACJP_00822 1e-132
HKIJACJP_00823 5.9e-132 yebC K Transcriptional regulatory protein
HKIJACJP_00824 1.3e-182 comGA NU Type II IV secretion system protein
HKIJACJP_00825 3e-182 comGB NU type II secretion system
HKIJACJP_00826 7.1e-47 comGC U competence protein ComGC
HKIJACJP_00827 4.1e-77 NU general secretion pathway protein
HKIJACJP_00828 3.2e-41
HKIJACJP_00829 1e-67
HKIJACJP_00831 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HKIJACJP_00832 1.7e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HKIJACJP_00833 0.0 S Bacterial membrane protein, YfhO
HKIJACJP_00834 1e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKIJACJP_00835 1.3e-167 I alpha/beta hydrolase fold
HKIJACJP_00836 2.5e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKIJACJP_00837 1.1e-119 tcyB E ABC transporter
HKIJACJP_00838 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKIJACJP_00839 6.2e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HKIJACJP_00840 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
HKIJACJP_00841 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKIJACJP_00842 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
HKIJACJP_00843 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HKIJACJP_00844 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKIJACJP_00845 1.1e-204 yacL S domain protein
HKIJACJP_00846 3.8e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKIJACJP_00847 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKIJACJP_00848 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKIJACJP_00849 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKIJACJP_00850 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKIJACJP_00851 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HKIJACJP_00852 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKIJACJP_00853 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKIJACJP_00854 8e-224 aadAT EK Aminotransferase, class I
HKIJACJP_00856 1.2e-123 S Alpha beta hydrolase
HKIJACJP_00857 3.3e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKIJACJP_00858 1.3e-97
HKIJACJP_00860 1.3e-122 yciB M ErfK YbiS YcfS YnhG
HKIJACJP_00861 1.2e-260 S Putative peptidoglycan binding domain
HKIJACJP_00862 3.9e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HKIJACJP_00863 1.6e-67
HKIJACJP_00864 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HKIJACJP_00865 8.9e-215 yttB EGP Major facilitator Superfamily
HKIJACJP_00866 2.6e-101
HKIJACJP_00867 1e-24
HKIJACJP_00868 2.5e-172 scrR K Transcriptional regulator, LacI family
HKIJACJP_00869 2.9e-235 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKIJACJP_00870 9.2e-50 czrA K Transcriptional regulator, ArsR family
HKIJACJP_00871 2.5e-36
HKIJACJP_00872 0.0 yhcA V ABC transporter, ATP-binding protein
HKIJACJP_00873 5e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HKIJACJP_00874 4e-166 hrtB V ABC transporter permease
HKIJACJP_00875 1.8e-84 ygfC K transcriptional regulator (TetR family)
HKIJACJP_00876 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HKIJACJP_00877 8.9e-287 mntH P H( )-stimulated, divalent metal cation uptake system
HKIJACJP_00878 8.3e-193 L transposase IS116 IS110 IS902 family protein
HKIJACJP_00879 9.7e-123 L Transposase
HKIJACJP_00880 4.8e-65 L Transposase
HKIJACJP_00881 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKIJACJP_00882 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKIJACJP_00883 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKIJACJP_00884 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HKIJACJP_00885 2.3e-199 ykiI
HKIJACJP_00886 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKIJACJP_00887 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKIJACJP_00888 1e-110 K Bacterial regulatory proteins, tetR family
HKIJACJP_00889 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKIJACJP_00890 4.4e-77 ctsR K Belongs to the CtsR family
HKIJACJP_00891 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HKIJACJP_00892 1e-154 S Hydrolases of the alpha beta superfamily
HKIJACJP_00893 4.3e-107 yvyE 3.4.13.9 S YigZ family
HKIJACJP_00894 1.6e-249 comFA L Helicase C-terminal domain protein
HKIJACJP_00895 1.1e-93 comFC S Competence protein
HKIJACJP_00896 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKIJACJP_00897 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKIJACJP_00898 1.1e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKIJACJP_00899 7.7e-31 KT PspC domain protein
HKIJACJP_00900 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HKIJACJP_00901 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKIJACJP_00902 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKIJACJP_00903 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HKIJACJP_00904 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKIJACJP_00905 1e-136 yrjD S LUD domain
HKIJACJP_00906 3e-292 lutB C 4Fe-4S dicluster domain
HKIJACJP_00907 7.8e-168 lutA C Cysteine-rich domain
HKIJACJP_00908 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKIJACJP_00909 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HKIJACJP_00910 1.4e-161 aatB ET PFAM extracellular solute-binding protein, family 3
HKIJACJP_00911 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
HKIJACJP_00912 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKIJACJP_00913 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HKIJACJP_00914 8.1e-79 F NUDIX domain
HKIJACJP_00915 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKIJACJP_00916 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKIJACJP_00917 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKIJACJP_00918 2.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
HKIJACJP_00919 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKIJACJP_00920 2.1e-160 dprA LU DNA protecting protein DprA
HKIJACJP_00921 5.1e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKIJACJP_00922 5.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKIJACJP_00923 4.4e-35 yozE S Belongs to the UPF0346 family
HKIJACJP_00924 2.8e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HKIJACJP_00925 2.4e-167 ypmR E lipolytic protein G-D-S-L family
HKIJACJP_00926 4.9e-151 DegV S EDD domain protein, DegV family
HKIJACJP_00927 1.9e-110 hlyIII S protein, hemolysin III
HKIJACJP_00928 9.6e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKIJACJP_00929 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKIJACJP_00930 0.0 yfmR S ABC transporter, ATP-binding protein
HKIJACJP_00931 8.2e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKIJACJP_00932 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HKIJACJP_00933 2.5e-127 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HKIJACJP_00934 2.7e-24 K helix_turn_helix, arabinose operon control protein
HKIJACJP_00935 1.3e-186 thrC 4.2.3.1 E Threonine synthase
HKIJACJP_00936 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HKIJACJP_00937 8.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKIJACJP_00938 4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKIJACJP_00939 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKIJACJP_00940 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKIJACJP_00941 4.4e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HKIJACJP_00942 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKIJACJP_00943 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKIJACJP_00944 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKIJACJP_00945 5.8e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKIJACJP_00946 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HKIJACJP_00947 3.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKIJACJP_00948 1e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HKIJACJP_00949 1.6e-243 purD 6.3.4.13 F Belongs to the GARS family
HKIJACJP_00950 1.2e-22 T Toxin-antitoxin system, toxin component, MazF family
HKIJACJP_00951 2e-36
HKIJACJP_00952 1.5e-06 D nuclear chromosome segregation
HKIJACJP_00953 0.0 snf 2.7.11.1 KL domain protein
HKIJACJP_00954 5.9e-143 ywqE 3.1.3.48 GM PHP domain protein
HKIJACJP_00955 4.9e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKIJACJP_00956 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HKIJACJP_00957 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKIJACJP_00958 7.3e-71
HKIJACJP_00959 3.1e-101 fic D Fic/DOC family
HKIJACJP_00960 3.1e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKIJACJP_00961 1.7e-151 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HKIJACJP_00962 1.3e-28
HKIJACJP_00963 1.3e-146
HKIJACJP_00964 1.2e-24
HKIJACJP_00965 1e-25
HKIJACJP_00966 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
HKIJACJP_00967 4.2e-99 lacA 2.3.1.79 S Transferase hexapeptide repeat
HKIJACJP_00968 4.1e-153 glcU U sugar transport
HKIJACJP_00969 3.8e-271 yclK 2.7.13.3 T Histidine kinase
HKIJACJP_00970 1.2e-134 K response regulator
HKIJACJP_00972 1.3e-76 lytE M Lysin motif
HKIJACJP_00973 1.1e-147 XK27_02985 S Cof-like hydrolase
HKIJACJP_00974 1.8e-78 K Transcriptional regulator
HKIJACJP_00975 0.0 oatA I Acyltransferase
HKIJACJP_00976 5.6e-52
HKIJACJP_00977 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKIJACJP_00978 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKIJACJP_00979 1.3e-125 ybbR S YbbR-like protein
HKIJACJP_00980 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKIJACJP_00981 3.7e-249 fucP G Major Facilitator Superfamily
HKIJACJP_00982 5.1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKIJACJP_00983 6.1e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKIJACJP_00984 3e-167 murB 1.3.1.98 M Cell wall formation
HKIJACJP_00990 9e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HKIJACJP_00991 1.5e-275 lysP E amino acid
HKIJACJP_00992 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
HKIJACJP_00993 9.8e-118 lssY 3.6.1.27 I phosphatase
HKIJACJP_00994 1.4e-81 S Threonine/Serine exporter, ThrE
HKIJACJP_00995 2e-127 thrE S Putative threonine/serine exporter
HKIJACJP_00996 1e-30 cspC K Cold shock protein
HKIJACJP_00997 1.6e-123 sirR K iron dependent repressor
HKIJACJP_00998 5.5e-164 czcD P cation diffusion facilitator family transporter
HKIJACJP_00999 2.5e-116 S membrane
HKIJACJP_01000 6.4e-109 S VIT family
HKIJACJP_01001 5.5e-83 usp1 T Belongs to the universal stress protein A family
HKIJACJP_01002 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKIJACJP_01003 2.8e-151 glnH ET ABC transporter
HKIJACJP_01004 2.4e-110 gluC P ABC transporter permease
HKIJACJP_01005 3.6e-109 glnP P ABC transporter permease
HKIJACJP_01006 8.3e-221 S CAAX protease self-immunity
HKIJACJP_01007 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKIJACJP_01008 7.9e-55
HKIJACJP_01009 9.8e-74 merR K MerR HTH family regulatory protein
HKIJACJP_01010 3.6e-269 lmrB EGP Major facilitator Superfamily
HKIJACJP_01011 2.9e-123 S Domain of unknown function (DUF4811)
HKIJACJP_01012 6.9e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKIJACJP_01013 6.8e-37 veg S Biofilm formation stimulator VEG
HKIJACJP_01014 1e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKIJACJP_01015 1.2e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKIJACJP_01016 1e-153 tatD L hydrolase, TatD family
HKIJACJP_01017 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKIJACJP_01018 1.2e-160 yunF F Protein of unknown function DUF72
HKIJACJP_01020 4e-130 cobB K SIR2 family
HKIJACJP_01021 8.6e-176
HKIJACJP_01022 9.1e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HKIJACJP_01023 4.6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HKIJACJP_01024 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKIJACJP_01025 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HKIJACJP_01026 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
HKIJACJP_01027 0.0 helD 3.6.4.12 L DNA helicase
HKIJACJP_01028 4.5e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKIJACJP_01030 1.7e-232 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKIJACJP_01031 6.1e-55
HKIJACJP_01032 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKIJACJP_01034 1.9e-231 yfmL L DEAD DEAH box helicase
HKIJACJP_01035 5.9e-191 mocA S Oxidoreductase
HKIJACJP_01036 9.1e-62 S Domain of unknown function (DUF4828)
HKIJACJP_01037 1.1e-104 yvdD 3.2.2.10 S Belongs to the LOG family
HKIJACJP_01038 1.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HKIJACJP_01039 2.2e-295 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HKIJACJP_01040 3e-195 S Protein of unknown function (DUF3114)
HKIJACJP_01041 5.5e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HKIJACJP_01042 1.1e-116 ybhL S Belongs to the BI1 family
HKIJACJP_01043 1.1e-92 K Acetyltransferase (GNAT) family
HKIJACJP_01044 6e-76 K LytTr DNA-binding domain
HKIJACJP_01045 6.8e-67 S Protein of unknown function (DUF3021)
HKIJACJP_01046 1.2e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HKIJACJP_01047 2.4e-75 ogt 2.1.1.63 L Methyltransferase
HKIJACJP_01048 2.6e-29 pnb C nitroreductase
HKIJACJP_01049 1.4e-65 pnb C nitroreductase
HKIJACJP_01050 1.7e-91
HKIJACJP_01051 1.9e-83 yvbK 3.1.3.25 K GNAT family
HKIJACJP_01052 6.8e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HKIJACJP_01053 3.7e-205 amtB P ammonium transporter
HKIJACJP_01054 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKIJACJP_01055 9.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKIJACJP_01056 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKIJACJP_01057 1.8e-134
HKIJACJP_01058 1.2e-145 rfbJ M Glycosyl transferase family 2
HKIJACJP_01059 5.8e-83
HKIJACJP_01060 2.6e-72 S Acyltransferase family
HKIJACJP_01061 1.3e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HKIJACJP_01062 1.8e-67 S Glycosyltransferase like family
HKIJACJP_01063 3.4e-76 rgpB GT2 M Glycosyl transferase family 2
HKIJACJP_01064 3.9e-28 M biosynthesis protein
HKIJACJP_01065 3.1e-90 cps3F
HKIJACJP_01066 4.7e-76 M transferase activity, transferring glycosyl groups
HKIJACJP_01067 3.2e-211 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HKIJACJP_01068 3.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
HKIJACJP_01069 1.5e-15 clcA P chloride
HKIJACJP_01070 1.2e-95 clcA P chloride
HKIJACJP_01071 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HKIJACJP_01072 1.9e-102 proW P ABC transporter, permease protein
HKIJACJP_01073 6.5e-142 proV E ABC transporter, ATP-binding protein
HKIJACJP_01074 2.4e-108 proWZ P ABC transporter permease
HKIJACJP_01075 7e-164 proX M ABC transporter, substrate-binding protein, QAT family
HKIJACJP_01076 8.4e-73 K Transcriptional regulator
HKIJACJP_01077 1.9e-51 1.6.5.2 GM NAD(P)H-binding
HKIJACJP_01078 1.6e-35 1.6.5.2 GM NAD(P)H-binding
HKIJACJP_01080 1.1e-220 5.4.2.7 G Metalloenzyme superfamily
HKIJACJP_01081 2.5e-311 cadA P P-type ATPase
HKIJACJP_01082 1.3e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HKIJACJP_01083 2.3e-125
HKIJACJP_01084 2.6e-52 S Sugar efflux transporter for intercellular exchange
HKIJACJP_01085 8.5e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HKIJACJP_01087 0.0 L Helicase C-terminal domain protein
HKIJACJP_01088 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HKIJACJP_01089 1.8e-178 S Aldo keto reductase
HKIJACJP_01091 8.4e-37 L PFAM Integrase catalytic region
HKIJACJP_01092 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKIJACJP_01094 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKIJACJP_01095 1.7e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HKIJACJP_01096 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKIJACJP_01097 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKIJACJP_01098 1.2e-244 yifK E Amino acid permease
HKIJACJP_01099 3.1e-292 clcA P chloride
HKIJACJP_01100 1.8e-34 secG U Preprotein translocase
HKIJACJP_01101 5.9e-143 est 3.1.1.1 S Serine aminopeptidase, S33
HKIJACJP_01102 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKIJACJP_01103 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKIJACJP_01104 1.4e-104 yxjI
HKIJACJP_01105 9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKIJACJP_01106 3.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HKIJACJP_01107 2e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HKIJACJP_01108 2.3e-87 K Acetyltransferase (GNAT) domain
HKIJACJP_01109 4.4e-76 S PAS domain
HKIJACJP_01110 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
HKIJACJP_01111 6.3e-146 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HKIJACJP_01113 1.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKIJACJP_01114 7.5e-58
HKIJACJP_01115 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
HKIJACJP_01116 9.7e-127 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKIJACJP_01117 9.4e-50
HKIJACJP_01118 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKIJACJP_01119 1.9e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKIJACJP_01120 4.6e-165 yniA G Phosphotransferase enzyme family
HKIJACJP_01121 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKIJACJP_01122 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HKIJACJP_01123 1.1e-262 glnPH2 P ABC transporter permease
HKIJACJP_01124 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HKIJACJP_01125 8.6e-70 yqeY S YqeY-like protein
HKIJACJP_01126 7.8e-73 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKIJACJP_01127 3.7e-96 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKIJACJP_01128 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKIJACJP_01129 6e-263 argH 4.3.2.1 E argininosuccinate lyase
HKIJACJP_01130 6.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HKIJACJP_01131 7.1e-63
HKIJACJP_01132 4e-14
HKIJACJP_01133 5.8e-59
HKIJACJP_01134 1.8e-38
HKIJACJP_01135 1.1e-134 V ABC transporter
HKIJACJP_01136 2.6e-211 EGP Major facilitator Superfamily
HKIJACJP_01137 6.8e-254 G PTS system Galactitol-specific IIC component
HKIJACJP_01138 9.8e-23 1.6.5.5 C Zinc-binding dehydrogenase
HKIJACJP_01139 2e-86 1.6.5.5 C Zinc-binding dehydrogenase
HKIJACJP_01140 1e-159
HKIJACJP_01141 1e-72 K Transcriptional regulator
HKIJACJP_01142 2e-172 D Alpha beta
HKIJACJP_01143 6.4e-52 ypaA S Protein of unknown function (DUF1304)
HKIJACJP_01144 0.0 yjcE P Sodium proton antiporter
HKIJACJP_01145 1.6e-52 yvlA
HKIJACJP_01146 6.6e-111 P Cobalt transport protein
HKIJACJP_01147 4.9e-249 cbiO1 S ABC transporter, ATP-binding protein
HKIJACJP_01148 1.3e-96 S ABC-type cobalt transport system, permease component
HKIJACJP_01149 9.6e-133 S membrane transporter protein
HKIJACJP_01150 1.2e-112 IQ KR domain
HKIJACJP_01151 2e-09 IQ KR domain
HKIJACJP_01152 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HKIJACJP_01153 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HKIJACJP_01154 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKIJACJP_01155 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKIJACJP_01156 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKIJACJP_01157 7.1e-164 S Tetratricopeptide repeat
HKIJACJP_01158 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKIJACJP_01159 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKIJACJP_01160 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HKIJACJP_01161 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
HKIJACJP_01162 0.0 comEC S Competence protein ComEC
HKIJACJP_01163 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
HKIJACJP_01164 5.8e-80 comEA L Competence protein ComEA
HKIJACJP_01165 1.9e-197 ylbL T Belongs to the peptidase S16 family
HKIJACJP_01166 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKIJACJP_01167 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HKIJACJP_01168 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HKIJACJP_01169 7.7e-222 ftsW D Belongs to the SEDS family
HKIJACJP_01170 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
HKIJACJP_01171 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKIJACJP_01172 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKIJACJP_01173 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HKIJACJP_01174 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
HKIJACJP_01175 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKIJACJP_01176 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKIJACJP_01177 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HKIJACJP_01178 3.4e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKIJACJP_01179 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKIJACJP_01180 1.3e-72 L PFAM Integrase catalytic region
HKIJACJP_01182 2.9e-81 ydcK S Belongs to the SprT family
HKIJACJP_01183 0.0 yhgF K Tex-like protein N-terminal domain protein
HKIJACJP_01184 2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKIJACJP_01185 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKIJACJP_01186 5.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
HKIJACJP_01187 2.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HKIJACJP_01188 1e-301 aspT P Predicted Permease Membrane Region
HKIJACJP_01189 8.5e-249 EGP Major facilitator Superfamily
HKIJACJP_01190 8.5e-111
HKIJACJP_01193 5.9e-149 yjjH S Calcineurin-like phosphoesterase
HKIJACJP_01194 1.3e-263 dtpT U amino acid peptide transporter
HKIJACJP_01198 5.4e-286 L Transposase IS66 family
HKIJACJP_01199 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HKIJACJP_01200 4.9e-99 yceD S Uncharacterized ACR, COG1399
HKIJACJP_01201 5.3e-209 ylbM S Belongs to the UPF0348 family
HKIJACJP_01202 9.7e-135 yqeM Q Methyltransferase
HKIJACJP_01203 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKIJACJP_01204 6.2e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HKIJACJP_01205 4.5e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKIJACJP_01206 1.9e-47 yhbY J RNA-binding protein
HKIJACJP_01207 4.8e-218 yqeH S Ribosome biogenesis GTPase YqeH
HKIJACJP_01208 2.4e-95 yqeG S HAD phosphatase, family IIIA
HKIJACJP_01209 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKIJACJP_01210 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HKIJACJP_01211 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKIJACJP_01212 1.9e-172 dnaI L Primosomal protein DnaI
HKIJACJP_01213 5.9e-223 dnaB L replication initiation and membrane attachment
HKIJACJP_01214 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKIJACJP_01215 1.7e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKIJACJP_01216 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKIJACJP_01217 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKIJACJP_01218 2e-115 yoaK S Protein of unknown function (DUF1275)
HKIJACJP_01219 1.5e-121 K response regulator
HKIJACJP_01220 4.1e-278 arlS 2.7.13.3 T Histidine kinase
HKIJACJP_01221 7.4e-267 yjeM E Amino Acid
HKIJACJP_01222 2.9e-235 V MatE
HKIJACJP_01223 1.3e-67 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKIJACJP_01224 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKIJACJP_01225 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HKIJACJP_01226 1.8e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKIJACJP_01227 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKIJACJP_01228 6.7e-59 yodB K Transcriptional regulator, HxlR family
HKIJACJP_01229 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKIJACJP_01230 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKIJACJP_01231 5.6e-115 rlpA M PFAM NLP P60 protein
HKIJACJP_01232 2.3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
HKIJACJP_01233 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKIJACJP_01234 4.4e-122 arcD S C4-dicarboxylate anaerobic carrier
HKIJACJP_01235 1.1e-180 yfeX P Peroxidase
HKIJACJP_01236 2.6e-91 lsa S ABC transporter
HKIJACJP_01237 3.8e-114 lsa S ABC transporter
HKIJACJP_01238 3e-133 I alpha/beta hydrolase fold
HKIJACJP_01239 4e-179 MA20_14895 S Conserved hypothetical protein 698
HKIJACJP_01240 8.4e-85 S NADPH-dependent FMN reductase
HKIJACJP_01241 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKIJACJP_01242 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HKIJACJP_01243 2e-231 mntH P H( )-stimulated, divalent metal cation uptake system
HKIJACJP_01244 2.4e-79 Q Methyltransferase
HKIJACJP_01245 7.7e-115 ktrA P domain protein
HKIJACJP_01246 7.6e-239 ktrB P Potassium uptake protein
HKIJACJP_01247 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HKIJACJP_01250 5.2e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
HKIJACJP_01251 8.3e-34
HKIJACJP_01252 3.6e-07 L Resolvase, N terminal domain
HKIJACJP_01253 1.9e-185 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
HKIJACJP_01254 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
HKIJACJP_01255 2.2e-50
HKIJACJP_01257 3.5e-12
HKIJACJP_01259 0.0 copB 3.6.3.4 P P-type ATPase
HKIJACJP_01260 6.5e-75 K Copper transport repressor CopY TcrY
HKIJACJP_01261 3.4e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HKIJACJP_01262 1.5e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HKIJACJP_01263 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKIJACJP_01264 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
HKIJACJP_01265 1.4e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKIJACJP_01266 2.2e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HKIJACJP_01267 2.2e-50 maa 2.3.1.79 S Maltose O-acetyltransferase
HKIJACJP_01268 9.2e-29 maa 2.3.1.79 S Maltose O-acetyltransferase
HKIJACJP_01269 7.3e-155 ytbE 1.1.1.346 S Aldo keto reductase
HKIJACJP_01270 1.4e-203 araR K Transcriptional regulator
HKIJACJP_01271 4.3e-83 usp6 T universal stress protein
HKIJACJP_01272 1.7e-45
HKIJACJP_01273 7.9e-233 rarA L recombination factor protein RarA
HKIJACJP_01274 5.1e-84 yueI S Protein of unknown function (DUF1694)
HKIJACJP_01275 4.6e-21
HKIJACJP_01277 2e-184 S PglZ domain
HKIJACJP_01278 2.6e-49 doc S Fic/DOC family
HKIJACJP_01280 2.8e-296 2.1.1.72 LV Eco57I restriction-modification methylase
HKIJACJP_01281 1e-221 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HKIJACJP_01282 1.7e-49 S Domain of unknown function (DUF1788)
HKIJACJP_01283 4.4e-45 S Putative inner membrane protein (DUF1819)
HKIJACJP_01285 1.2e-120 GM NmrA-like family
HKIJACJP_01286 1.8e-50 hxlR K Transcriptional regulator, HxlR family
HKIJACJP_01287 4.1e-107 XK27_02070 S Nitroreductase family
HKIJACJP_01288 1.2e-82 K Transcriptional regulator, HxlR family
HKIJACJP_01289 1.6e-233
HKIJACJP_01290 1.4e-209 EGP Major facilitator Superfamily
HKIJACJP_01291 3e-256 pepC 3.4.22.40 E aminopeptidase
HKIJACJP_01292 6e-109 ylbE GM NAD dependent epimerase dehydratase family protein
HKIJACJP_01293 0.0 pepN 3.4.11.2 E aminopeptidase
HKIJACJP_01294 1.9e-48 K Transcriptional regulator
HKIJACJP_01295 2.3e-24 folT S ECF transporter, substrate-specific component
HKIJACJP_01296 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
HKIJACJP_01297 5.1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HKIJACJP_01298 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKIJACJP_01299 6.7e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HKIJACJP_01300 0.0 pacL 3.6.3.8 P P-type ATPase
HKIJACJP_01301 9.9e-85 dps P Belongs to the Dps family
HKIJACJP_01302 4.8e-177 yagE E amino acid
HKIJACJP_01303 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HKIJACJP_01304 2e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HKIJACJP_01305 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HKIJACJP_01306 1.1e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HKIJACJP_01307 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
HKIJACJP_01308 1e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKIJACJP_01309 3.4e-35 nrdH O Glutaredoxin
HKIJACJP_01310 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKIJACJP_01311 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKIJACJP_01312 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HKIJACJP_01313 1.3e-131 S Putative adhesin
HKIJACJP_01314 3.2e-83 XK27_06920 S Protein of unknown function (DUF1700)
HKIJACJP_01315 2.4e-56 K transcriptional regulator PadR family
HKIJACJP_01316 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKIJACJP_01318 3.4e-48
HKIJACJP_01319 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKIJACJP_01320 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKIJACJP_01321 2.3e-173 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKIJACJP_01322 3.1e-33 L transposase and inactivated derivatives, IS30 family
HKIJACJP_01323 2.1e-276 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HKIJACJP_01324 3.5e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HKIJACJP_01325 3e-156 rssA S Phospholipase, patatin family
HKIJACJP_01326 9.4e-118 L Integrase
HKIJACJP_01327 4.2e-153 EG EamA-like transporter family
HKIJACJP_01328 9.6e-129 narI 1.7.5.1 C Nitrate reductase
HKIJACJP_01329 1.1e-53 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HKIJACJP_01330 2.6e-33 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HKIJACJP_01331 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HKIJACJP_01332 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKIJACJP_01333 1.6e-166 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HKIJACJP_01334 6.7e-99 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HKIJACJP_01335 7.3e-115 K Transcriptional regulator
HKIJACJP_01336 3.2e-292 M Exporter of polyketide antibiotics
HKIJACJP_01337 2e-169 yjjC V ABC transporter
HKIJACJP_01338 3.1e-104 L Integrase
HKIJACJP_01339 1.7e-33 S RelB antitoxin
HKIJACJP_01340 3e-44
HKIJACJP_01342 1.9e-204
HKIJACJP_01343 3.1e-59
HKIJACJP_01344 2.4e-31 S CAAX protease self-immunity
HKIJACJP_01345 6e-93 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
HKIJACJP_01346 2.4e-17 pre D plasmid recombination enzyme
HKIJACJP_01347 2.1e-31 L Transposase IS66 family
HKIJACJP_01348 1.2e-221 fhaB M Rib/alpha-like repeat
HKIJACJP_01354 2.2e-07 S Domain of unknown function (DUF3173)
HKIJACJP_01355 4.3e-87 L Belongs to the 'phage' integrase family
HKIJACJP_01356 2.1e-40 L Transposase
HKIJACJP_01357 3e-75 L Transposase
HKIJACJP_01358 1.9e-43 L Transposase
HKIJACJP_01359 3.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKIJACJP_01360 2.2e-203 XK27_09615 S reductase
HKIJACJP_01361 2.4e-101 nqr 1.5.1.36 S reductase
HKIJACJP_01363 1.7e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKIJACJP_01364 3.8e-174 K Transcriptional regulator, LacI family
HKIJACJP_01365 6.1e-260 G Major Facilitator
HKIJACJP_01366 3.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKIJACJP_01367 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HKIJACJP_01369 1.3e-201 xerS L Belongs to the 'phage' integrase family
HKIJACJP_01371 8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKIJACJP_01372 4.7e-76 marR K Transcriptional regulator, MarR family
HKIJACJP_01373 1.8e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKIJACJP_01374 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKIJACJP_01375 2.9e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HKIJACJP_01376 1.2e-124 IQ reductase
HKIJACJP_01377 1.4e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKIJACJP_01378 7.6e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKIJACJP_01379 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKIJACJP_01380 1.6e-255 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HKIJACJP_01381 8.4e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKIJACJP_01382 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HKIJACJP_01383 4.3e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HKIJACJP_01388 2.1e-144 K Transcriptional regulator
HKIJACJP_01389 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HKIJACJP_01390 2.3e-155 ypuA S Protein of unknown function (DUF1002)
HKIJACJP_01391 6.6e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HKIJACJP_01392 5.1e-153 tesE Q hydratase
HKIJACJP_01393 2.2e-119 S Alpha beta hydrolase
HKIJACJP_01394 1.5e-65 lacA S transferase hexapeptide repeat
HKIJACJP_01395 8.7e-82 S Peptidase propeptide and YPEB domain
HKIJACJP_01396 1.3e-214 T GHKL domain
HKIJACJP_01397 1.6e-109 T Transcriptional regulatory protein, C terminal
HKIJACJP_01398 5.9e-18 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
HKIJACJP_01400 3.1e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKIJACJP_01401 0.0 M NlpC/P60 family
HKIJACJP_01402 0.0 S Peptidase, M23
HKIJACJP_01403 0.0 bamA GM domain, Protein
HKIJACJP_01404 1.1e-199
HKIJACJP_01405 8.5e-65 repB L Initiator Replication protein
HKIJACJP_01407 6.2e-35 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HKIJACJP_01408 9.3e-168 arsB 1.20.4.1 P Sodium Bile acid symporter family
HKIJACJP_01409 4e-27 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKIJACJP_01410 1.3e-42 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HKIJACJP_01411 4.4e-31 arsB 1.20.4.1 P Sodium Bile acid symporter family
HKIJACJP_01412 2.4e-12 fhaB M Rib/alpha-like repeat
HKIJACJP_01413 0.0 tetP J Elongation factor G, domain IV
HKIJACJP_01415 1.2e-95 L Integrase
HKIJACJP_01416 2e-53 S Phage derived protein Gp49-like (DUF891)
HKIJACJP_01417 3.5e-37 K Helix-turn-helix domain
HKIJACJP_01419 0.0 2.7.7.6 M Peptidase family M23
HKIJACJP_01420 2.1e-117 rfbP 2.7.8.6 M Bacterial sugar transferase
HKIJACJP_01421 2.3e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HKIJACJP_01422 1.9e-146 cps1D M Domain of unknown function (DUF4422)
HKIJACJP_01423 1.2e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
HKIJACJP_01424 4.9e-31
HKIJACJP_01425 6.6e-34 S Protein of unknown function (DUF2922)
HKIJACJP_01426 1.8e-143 yihY S Belongs to the UPF0761 family
HKIJACJP_01427 3.4e-280 yjeM E Amino Acid
HKIJACJP_01428 9.5e-256 E Arginine ornithine antiporter
HKIJACJP_01430 5.5e-248 mmuP E amino acid
HKIJACJP_01431 1.4e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HKIJACJP_01432 1.1e-43
HKIJACJP_01434 1.8e-09
HKIJACJP_01435 4.8e-50 doc S Fic/DOC family
HKIJACJP_01436 5.5e-29 S Protein of unknown function (DUF4065)
HKIJACJP_01438 3.2e-53 YPO0284 GM NAD(P)H-binding
HKIJACJP_01440 1.2e-100
HKIJACJP_01441 4e-21
HKIJACJP_01442 1.1e-84 L Transposase IS66 family
HKIJACJP_01443 3.7e-10 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
HKIJACJP_01444 8.5e-10 L Resolvase, N terminal domain
HKIJACJP_01445 9.8e-79 L Resolvase, N terminal domain
HKIJACJP_01446 5.3e-125
HKIJACJP_01447 0.0
HKIJACJP_01449 1.4e-33 S Domain of unknown function (DUF3173)
HKIJACJP_01450 4.9e-229 L Belongs to the 'phage' integrase family
HKIJACJP_01451 2.9e-224 oxlT P Major Facilitator Superfamily
HKIJACJP_01452 2.1e-160 spoU 2.1.1.185 J Methyltransferase
HKIJACJP_01453 3.4e-92 ywlG S Belongs to the UPF0340 family
HKIJACJP_01454 1.5e-169 whiA K May be required for sporulation
HKIJACJP_01455 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HKIJACJP_01456 4.6e-160 rapZ S Displays ATPase and GTPase activities
HKIJACJP_01457 1.6e-244 steT E amino acid
HKIJACJP_01458 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKIJACJP_01459 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKIJACJP_01460 6.9e-14
HKIJACJP_01461 1.9e-115 yfbR S HD containing hydrolase-like enzyme
HKIJACJP_01462 2.7e-120 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HKIJACJP_01463 1.5e-139 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKIJACJP_01464 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
HKIJACJP_01465 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HKIJACJP_01466 4.2e-272 pipD E Dipeptidase
HKIJACJP_01467 7.3e-293 yjbQ P TrkA C-terminal domain protein
HKIJACJP_01468 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HKIJACJP_01469 3.3e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKIJACJP_01470 3.2e-89
HKIJACJP_01471 8.1e-35
HKIJACJP_01472 2.3e-08 K Transcriptional regulator, HxlR family
HKIJACJP_01473 2.2e-57
HKIJACJP_01475 3.8e-130 mltD CBM50 M NlpC P60 family protein
HKIJACJP_01476 1.3e-28
HKIJACJP_01477 4.3e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HKIJACJP_01478 9.8e-32 ykzG S Belongs to the UPF0356 family
HKIJACJP_01479 5.3e-78
HKIJACJP_01480 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKIJACJP_01481 1.3e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HKIJACJP_01482 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HKIJACJP_01483 1.3e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKIJACJP_01484 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
HKIJACJP_01485 9.4e-40 L Transposase
HKIJACJP_01486 0.0 rafA 3.2.1.22 G alpha-galactosidase
HKIJACJP_01487 5.7e-186 galR K Periplasmic binding protein-like domain
HKIJACJP_01488 6.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HKIJACJP_01489 6.2e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKIJACJP_01490 1.3e-45 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HKIJACJP_01491 4e-148 f42a O Band 7 protein
HKIJACJP_01492 2.7e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HKIJACJP_01493 1.7e-153 yitU 3.1.3.104 S hydrolase
HKIJACJP_01494 2.7e-38 S Cytochrome B5
HKIJACJP_01495 1.3e-160 EG EamA-like transporter family
HKIJACJP_01496 8.1e-123 dnaD L DnaD domain protein
HKIJACJP_01497 6.9e-87 ypmB S Protein conserved in bacteria
HKIJACJP_01498 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HKIJACJP_01499 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HKIJACJP_01500 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HKIJACJP_01501 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HKIJACJP_01502 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKIJACJP_01503 2.5e-86 S Protein of unknown function (DUF1440)
HKIJACJP_01504 8.3e-19 S PFAM Archaeal ATPase
HKIJACJP_01505 1.6e-178 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKIJACJP_01506 1.7e-17 K Winged helix DNA-binding domain
HKIJACJP_01507 2.9e-299 lmrA V ABC transporter, ATP-binding protein
HKIJACJP_01508 0.0 yfiC V ABC transporter
HKIJACJP_01509 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HKIJACJP_01510 5.8e-269 pipD E Dipeptidase
HKIJACJP_01511 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKIJACJP_01512 1.6e-67 yneR S Belongs to the HesB IscA family
HKIJACJP_01513 0.0 S membrane
HKIJACJP_01514 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HKIJACJP_01515 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKIJACJP_01516 6.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKIJACJP_01517 6.2e-109 gluP 3.4.21.105 S Peptidase, S54 family
HKIJACJP_01518 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HKIJACJP_01519 2.1e-182 glk 2.7.1.2 G Glucokinase
HKIJACJP_01520 3.4e-67 yqhL P Rhodanese-like protein
HKIJACJP_01521 5.9e-22 S Protein of unknown function (DUF3042)
HKIJACJP_01522 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKIJACJP_01523 5.5e-29 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HKIJACJP_01524 9.1e-49
HKIJACJP_01525 3.4e-205 nrnB S DHHA1 domain
HKIJACJP_01526 6.2e-227 S Uncharacterized protein conserved in bacteria (DUF2325)
HKIJACJP_01527 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
HKIJACJP_01528 1.1e-104 NU mannosyl-glycoprotein
HKIJACJP_01529 5e-142 S Putative ABC-transporter type IV
HKIJACJP_01530 7.1e-273 S ABC transporter, ATP-binding protein
HKIJACJP_01531 6.4e-08 S HTH domain
HKIJACJP_01532 1.1e-13 K Transcriptional
HKIJACJP_01533 4.5e-51 L Integrase
HKIJACJP_01534 1e-28 WQ51_00220 K Helix-turn-helix domain
HKIJACJP_01535 6e-98 S Protein of unknown function (DUF3278)
HKIJACJP_01536 1.7e-73 M PFAM NLP P60 protein
HKIJACJP_01537 4.1e-181 ABC-SBP S ABC transporter
HKIJACJP_01538 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HKIJACJP_01539 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
HKIJACJP_01540 7.4e-95 P Cadmium resistance transporter
HKIJACJP_01541 4.9e-54 K Transcriptional regulator, ArsR family
HKIJACJP_01542 2.7e-236 mepA V MATE efflux family protein
HKIJACJP_01543 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HKIJACJP_01544 1e-270 ywfO S HD domain protein
HKIJACJP_01545 6.1e-146 yxeH S hydrolase
HKIJACJP_01546 9e-48
HKIJACJP_01547 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKIJACJP_01548 9.2e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKIJACJP_01549 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HKIJACJP_01550 4.7e-127 znuB U ABC 3 transport family
HKIJACJP_01551 2.2e-122 fhuC P ABC transporter
HKIJACJP_01552 9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
HKIJACJP_01553 2.1e-45 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKIJACJP_01554 1.8e-31
HKIJACJP_01555 3.6e-109 S CAAX protease self-immunity
HKIJACJP_01556 1.9e-43
HKIJACJP_01558 6.4e-69
HKIJACJP_01559 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKIJACJP_01560 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKIJACJP_01561 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HKIJACJP_01562 1e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKIJACJP_01563 1.6e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HKIJACJP_01564 3.4e-211 folP 2.5.1.15 H dihydropteroate synthase
HKIJACJP_01565 5.1e-43
HKIJACJP_01566 1.6e-39
HKIJACJP_01568 1.9e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKIJACJP_01569 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKIJACJP_01570 2.9e-09 L Resolvase, N terminal domain
HKIJACJP_01572 1e-78 L Resolvase, N terminal domain
HKIJACJP_01574 1.1e-12 S Helix-turn-helix domain
HKIJACJP_01575 3.3e-133
HKIJACJP_01578 3.1e-19 S Excisionase from transposon Tn916
HKIJACJP_01579 1.3e-168 L Belongs to the 'phage' integrase family
HKIJACJP_01580 9.9e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HKIJACJP_01581 3.3e-103 T Ion transport 2 domain protein
HKIJACJP_01582 0.0 S Bacterial membrane protein YfhO
HKIJACJP_01583 9.8e-206 G Transporter, major facilitator family protein
HKIJACJP_01584 7.1e-109 yvrI K sigma factor activity
HKIJACJP_01585 6.7e-60 ydiI Q Thioesterase superfamily
HKIJACJP_01586 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HKIJACJP_01587 5.8e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HKIJACJP_01588 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HKIJACJP_01589 9.3e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKIJACJP_01590 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HKIJACJP_01591 0.0 lacS G Transporter
HKIJACJP_01592 5.7e-186 lacR K Transcriptional regulator
HKIJACJP_01593 3.8e-10
HKIJACJP_01594 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
HKIJACJP_01595 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
HKIJACJP_01596 8.5e-34
HKIJACJP_01597 5.7e-115 nreC K PFAM regulatory protein LuxR
HKIJACJP_01598 2.6e-158 hipB K Helix-turn-helix
HKIJACJP_01599 2.8e-57 yitW S Iron-sulfur cluster assembly protein
HKIJACJP_01600 3.6e-271 sufB O assembly protein SufB
HKIJACJP_01601 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
HKIJACJP_01602 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKIJACJP_01603 5.1e-240 sufD O FeS assembly protein SufD
HKIJACJP_01604 1.9e-144 sufC O FeS assembly ATPase SufC
HKIJACJP_01605 2.8e-31 feoA P FeoA domain
HKIJACJP_01606 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HKIJACJP_01607 6.9e-60 asp S Asp23 family, cell envelope-related function
HKIJACJP_01608 6.1e-25
HKIJACJP_01609 2.6e-92
HKIJACJP_01610 3.7e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HKIJACJP_01611 2.1e-180 K Transcriptional regulator, LacI family
HKIJACJP_01612 1.5e-231 gntT EG Gluconate
HKIJACJP_01613 3e-292 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HKIJACJP_01614 2.9e-96 K Acetyltransferase (GNAT) domain
HKIJACJP_01615 5.4e-20
HKIJACJP_01616 2.4e-22
HKIJACJP_01617 2.2e-44
HKIJACJP_01618 7e-57 yhaI S Protein of unknown function (DUF805)
HKIJACJP_01619 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HKIJACJP_01620 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKIJACJP_01621 9.4e-38 yheA S Belongs to the UPF0342 family
HKIJACJP_01622 1.3e-218 yhaO L Ser Thr phosphatase family protein
HKIJACJP_01623 0.0 L AAA domain
HKIJACJP_01624 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKIJACJP_01625 1.4e-98 S Protein of unknown function (DUF2815)
HKIJACJP_01626 4e-212 L Protein of unknown function (DUF2800)
HKIJACJP_01627 2e-41
HKIJACJP_01628 8.5e-25
HKIJACJP_01629 6.5e-73 K DNA-templated transcription, initiation
HKIJACJP_01630 1.5e-18 S Domain of unknown function (DUF1837)
HKIJACJP_01631 8.9e-135 F helicase superfamily c-terminal domain
HKIJACJP_01632 4.9e-23 K Cro/C1-type HTH DNA-binding domain
HKIJACJP_01633 2.3e-72 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HKIJACJP_01634 1.1e-12 KL Eco57I restriction-modification methylase
HKIJACJP_01635 3e-97 4.1.1.35 M Male sterility protein
HKIJACJP_01636 3.5e-83 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HKIJACJP_01637 5.7e-81 tagB 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKIJACJP_01638 4e-45 MA20_17390 GT4 M Glycosyl transferases group 1
HKIJACJP_01639 6.8e-108 S Polysaccharide biosynthesis protein
HKIJACJP_01641 9.7e-58 M Glycosyltransferase like family 2
HKIJACJP_01642 4.3e-88
HKIJACJP_01643 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKIJACJP_01644 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HKIJACJP_01645 5.5e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKIJACJP_01646 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKIJACJP_01647 4.8e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKIJACJP_01648 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKIJACJP_01649 7.6e-09
HKIJACJP_01650 6.3e-38 ykuJ S Protein of unknown function (DUF1797)
HKIJACJP_01651 5.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKIJACJP_01652 2.9e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
HKIJACJP_01653 2.1e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HKIJACJP_01654 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKIJACJP_01655 2.7e-39 ptsH G phosphocarrier protein HPR
HKIJACJP_01656 6.4e-27
HKIJACJP_01657 0.0 clpE O Belongs to the ClpA ClpB family
HKIJACJP_01658 7.5e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
HKIJACJP_01659 8.4e-268 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HKIJACJP_01660 2.5e-13 M Lysin motif
HKIJACJP_01661 7.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HKIJACJP_01662 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HKIJACJP_01663 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HKIJACJP_01664 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKIJACJP_01665 1.4e-234 S Tetratricopeptide repeat protein
HKIJACJP_01666 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKIJACJP_01667 8.6e-119 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKIJACJP_01668 5.1e-238 E amino acid
HKIJACJP_01669 1.1e-130 npp S type I phosphodiesterase nucleotide pyrophosphatase
HKIJACJP_01670 6.3e-52 npp S type I phosphodiesterase nucleotide pyrophosphatase
HKIJACJP_01671 6e-214 yxiO S Vacuole effluxer Atg22 like
HKIJACJP_01673 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKIJACJP_01674 6.4e-32
HKIJACJP_01675 1.4e-243 nhaC C Na H antiporter NhaC
HKIJACJP_01676 1.6e-241 pbuX F xanthine permease
HKIJACJP_01677 2.3e-278 pipD E Dipeptidase
HKIJACJP_01678 2.8e-168 corA P CorA-like Mg2+ transporter protein
HKIJACJP_01679 3.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKIJACJP_01680 6.6e-131 terC P membrane
HKIJACJP_01681 1.9e-55 trxA O Belongs to the thioredoxin family
HKIJACJP_01682 5.5e-51 waaB GT4 M Glycosyl transferases group 1
HKIJACJP_01683 3.2e-44 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
HKIJACJP_01684 3.5e-42 tuaG GT2 M Glycosyltransferase like family 2
HKIJACJP_01685 3.8e-90 tuaA M Bacterial sugar transferase
HKIJACJP_01686 4e-138 cps2D 5.1.3.2 M RmlD substrate binding domain
HKIJACJP_01687 4.1e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HKIJACJP_01688 7.4e-142 epsB M biosynthesis protein
HKIJACJP_01689 2.9e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HKIJACJP_01690 2.9e-184 G Major Facilitator
HKIJACJP_01691 1.3e-124 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HKIJACJP_01692 3.9e-280 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HKIJACJP_01693 1.2e-269 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HKIJACJP_01694 9.9e-267 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HKIJACJP_01695 8.3e-72
HKIJACJP_01696 3.9e-12
HKIJACJP_01697 2.2e-154 P Belongs to the nlpA lipoprotein family
HKIJACJP_01698 1.4e-98 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKIJACJP_01699 4.8e-51 S Iron-sulfur cluster assembly protein
HKIJACJP_01700 2.6e-150
HKIJACJP_01701 3.3e-181
HKIJACJP_01702 2.8e-85 dut S Protein conserved in bacteria
HKIJACJP_01706 8e-103 K Transcriptional regulator
HKIJACJP_01707 1e-202 brnQ U Component of the transport system for branched-chain amino acids
HKIJACJP_01708 1.2e-137 aroD S Serine hydrolase (FSH1)
HKIJACJP_01709 3.6e-236 yagE E amino acid
HKIJACJP_01710 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HKIJACJP_01711 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
HKIJACJP_01712 6.2e-99 S D5 N terminal like
HKIJACJP_01713 3.1e-51 S Bifunctional DNA primase/polymerase, N-terminal
HKIJACJP_01715 8.5e-08
HKIJACJP_01718 4e-21 S Helix-turn-helix domain
HKIJACJP_01719 1e-16 K Transcriptional regulator
HKIJACJP_01720 1e-09 M LysM domain
HKIJACJP_01721 1.9e-134 L Belongs to the 'phage' integrase family
HKIJACJP_01723 1.7e-21
HKIJACJP_01725 1.7e-10
HKIJACJP_01727 6.3e-154 L Transposase
HKIJACJP_01728 2.4e-16 arcD S C4-dicarboxylate anaerobic carrier
HKIJACJP_01729 1.1e-124 arcD S C4-dicarboxylate anaerobic carrier
HKIJACJP_01730 4.3e-258 ytjP 3.5.1.18 E Dipeptidase
HKIJACJP_01731 1.3e-216 uhpT EGP Major facilitator Superfamily
HKIJACJP_01732 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HKIJACJP_01733 2.1e-143 ytxK 2.1.1.72 L N-6 DNA Methylase
HKIJACJP_01734 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKIJACJP_01735 4.7e-111 S Calcineurin-like phosphoesterase
HKIJACJP_01736 6.6e-93 yutD S Protein of unknown function (DUF1027)
HKIJACJP_01737 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKIJACJP_01738 2.8e-101 S Protein of unknown function (DUF1461)
HKIJACJP_01739 2.8e-50 dedA S SNARE-like domain protein
HKIJACJP_01740 8.4e-207 gldA 1.1.1.6 C dehydrogenase
HKIJACJP_01741 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKIJACJP_01742 1.3e-38
HKIJACJP_01743 4e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
HKIJACJP_01744 4.6e-36 K Bacterial transcriptional regulator
HKIJACJP_01746 1.2e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HKIJACJP_01747 4.6e-16 K Cro/C1-type HTH DNA-binding domain
HKIJACJP_01748 9.5e-80 L Transposase
HKIJACJP_01749 2.4e-36 L Transposase
HKIJACJP_01750 3.7e-40 L Transposase
HKIJACJP_01751 1.4e-12 K Transcriptional regulator, HxlR family
HKIJACJP_01752 3.9e-187
HKIJACJP_01753 1.2e-97 2.3.1.128 K acetyltransferase
HKIJACJP_01754 4e-83 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKIJACJP_01755 3.7e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HKIJACJP_01756 4.7e-63 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKIJACJP_01757 2.3e-84 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HKIJACJP_01758 6.5e-179 ABC-SBP S ABC transporter
HKIJACJP_01759 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKIJACJP_01761 2.9e-96 S reductase
HKIJACJP_01762 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HKIJACJP_01763 3.1e-113 yjbH Q Thioredoxin
HKIJACJP_01764 6.8e-267 pipD E Dipeptidase
HKIJACJP_01765 1.8e-195 coiA 3.6.4.12 S Competence protein
HKIJACJP_01766 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKIJACJP_01767 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKIJACJP_01768 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HKIJACJP_01769 5.7e-264 yfnA E amino acid
HKIJACJP_01770 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKIJACJP_01771 8.9e-41 1.3.5.4 S FMN binding
HKIJACJP_01772 8.3e-221 norA EGP Major facilitator Superfamily
HKIJACJP_01773 5.3e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HKIJACJP_01774 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
HKIJACJP_01775 4e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKIJACJP_01776 2.6e-155 pstA P Phosphate transport system permease protein PstA
HKIJACJP_01777 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
HKIJACJP_01778 4.6e-160 pstS P Phosphate
HKIJACJP_01779 5.1e-133 K Transcriptional regulatory protein, C-terminal domain protein
HKIJACJP_01780 2e-42 lytE M LysM domain protein
HKIJACJP_01781 1e-159 sufD O Uncharacterized protein family (UPF0051)
HKIJACJP_01782 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKIJACJP_01783 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HKIJACJP_01784 2.3e-31
HKIJACJP_01785 9.5e-18
HKIJACJP_01786 3.6e-65
HKIJACJP_01787 7.9e-34
HKIJACJP_01788 1.8e-206 potD P ABC transporter
HKIJACJP_01789 6.5e-140 potC P ABC transporter permease
HKIJACJP_01790 3.9e-145 potB P ABC transporter permease
HKIJACJP_01791 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKIJACJP_01792 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
HKIJACJP_01793 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKIJACJP_01794 3.9e-122 O Zinc-dependent metalloprotease
HKIJACJP_01795 1e-36 L Helix-turn-helix domain
HKIJACJP_01796 1.3e-16 L Transposase
HKIJACJP_01797 9.5e-39 S Cytochrome B5
HKIJACJP_01798 9.3e-161 degV S EDD domain protein, DegV family
HKIJACJP_01799 1.5e-89
HKIJACJP_01800 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKIJACJP_01801 1.8e-156 gspA M family 8
HKIJACJP_01802 8.1e-154 S Alpha beta hydrolase
HKIJACJP_01803 1.5e-94 K Acetyltransferase (GNAT) domain
HKIJACJP_01804 3.2e-99 dedA 3.1.3.1 S SNARE associated Golgi protein
HKIJACJP_01805 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKIJACJP_01806 1.4e-78 K AsnC family
HKIJACJP_01807 1.6e-79 uspA T universal stress protein
HKIJACJP_01808 6.8e-44 ltrA S Bacterial low temperature requirement A protein (LtrA)
HKIJACJP_01809 1.8e-65 ltrA S Bacterial low temperature requirement A protein (LtrA)
HKIJACJP_01810 4e-264 glnA 6.3.1.2 E glutamine synthetase
HKIJACJP_01811 4.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKIJACJP_01812 7e-22 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HKIJACJP_01813 1.2e-138 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HKIJACJP_01814 1.7e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HKIJACJP_01815 1.4e-222 G Glycosyl hydrolases family 8
HKIJACJP_01816 1.2e-241 ydaM M Glycosyl transferase
HKIJACJP_01818 1.2e-139
HKIJACJP_01819 3.7e-85 yxjG_1 E methionine synthase, vitamin-B12 independent
HKIJACJP_01820 8.9e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKIJACJP_01821 2.7e-222 mdtG EGP Major facilitator Superfamily
HKIJACJP_01822 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
HKIJACJP_01823 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKIJACJP_01824 1.4e-23 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HKIJACJP_01825 2.9e-210 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HKIJACJP_01826 6.8e-30 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HKIJACJP_01827 1.1e-138 S Belongs to the UPF0246 family
HKIJACJP_01828 1.4e-136 S Membrane
HKIJACJP_01829 6.8e-74 4.4.1.5 E Glyoxalase
HKIJACJP_01831 3.2e-77 hit FG histidine triad
HKIJACJP_01832 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HKIJACJP_01833 1.3e-218 ecsB U ABC transporter
HKIJACJP_01834 1.2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKIJACJP_01835 3.1e-22 S YSIRK type signal peptide
HKIJACJP_01836 1.3e-10 glsA 3.5.1.2 E Belongs to the glutaminase family
HKIJACJP_01837 1.8e-56 ytzB S Small secreted protein
HKIJACJP_01838 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKIJACJP_01839 5e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKIJACJP_01840 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HKIJACJP_01841 1.9e-119 ybhL S Belongs to the BI1 family
HKIJACJP_01842 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKIJACJP_01843 1.8e-166
HKIJACJP_01844 6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKIJACJP_01845 4.9e-69 L SNF2 family N-terminal domain
HKIJACJP_01846 8.9e-86
HKIJACJP_01847 3.1e-98
HKIJACJP_01848 2.9e-229 2.1.1.72 KL DNA methylase
HKIJACJP_01849 3.3e-112 S Psort location Cytoplasmic, score
HKIJACJP_01850 1.8e-30 S Domain of unknown function (DUF5049)
HKIJACJP_01851 1.1e-103 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKIJACJP_01852 2.7e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKIJACJP_01853 5.1e-165 L Integrase core domain
HKIJACJP_01854 1.4e-57 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKIJACJP_01857 5.1e-81 uspA T universal stress protein
HKIJACJP_01858 0.0 tetP J elongation factor G
HKIJACJP_01859 2.9e-165 GK ROK family
HKIJACJP_01860 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HKIJACJP_01861 7.4e-163 yueF S AI-2E family transporter
HKIJACJP_01862 3.1e-206 csd1 3.5.1.28 G domain, Protein
HKIJACJP_01864 0.0 L PLD-like domain
HKIJACJP_01865 1e-33 3.2.1.17 LO Uncharacterized conserved protein (DUF2075)
HKIJACJP_01866 3.9e-182
HKIJACJP_01867 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKIJACJP_01868 1.7e-183 S Phosphotransferase system, EIIC
HKIJACJP_01869 7.9e-28 L PFAM transposase IS200-family protein
HKIJACJP_01870 3e-159 K LysR substrate binding domain protein
HKIJACJP_01871 1.3e-165 1.1.1.346 C Aldo keto reductase
HKIJACJP_01872 8.7e-71 XK27_08635 S UPF0210 protein
HKIJACJP_01873 2.2e-72 XK27_08635 S UPF0210 protein
HKIJACJP_01874 2.6e-65 XK27_08635 S UPF0210 protein
HKIJACJP_01875 4.9e-111 lssY 3.6.1.27 I Acid phosphatase homologues
HKIJACJP_01876 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HKIJACJP_01877 4.8e-193 V Beta-lactamase
HKIJACJP_01878 2.7e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKIJACJP_01879 7e-104 yhiD S MgtC family
HKIJACJP_01880 7.3e-13 S GyrI-like small molecule binding domain
HKIJACJP_01881 5.9e-80 S GyrI-like small molecule binding domain
HKIJACJP_01882 1.9e-156 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HKIJACJP_01883 3.1e-103 metI P ABC transporter permease
HKIJACJP_01884 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKIJACJP_01885 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
HKIJACJP_01888 9.8e-15 K Cro/C1-type HTH DNA-binding domain
HKIJACJP_01889 2.5e-57 lmrB EGP Major facilitator Superfamily
HKIJACJP_01890 2.2e-152 lmrB EGP Major facilitator Superfamily
HKIJACJP_01891 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
HKIJACJP_01901 1.9e-37 T EAL domain
HKIJACJP_01902 2.1e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
HKIJACJP_01903 1.9e-59 yneR
HKIJACJP_01904 1.6e-101 qorB 1.6.5.2 GM NmrA-like family
HKIJACJP_01905 1.3e-160 akr5f 1.1.1.346 S reductase
HKIJACJP_01906 5.7e-228 clcA_2 P Chloride transporter, ClC family
HKIJACJP_01907 4.8e-139 L PFAM transposase IS116 IS110 IS902
HKIJACJP_01908 0.0 typA T GTP-binding protein TypA
HKIJACJP_01909 3.8e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HKIJACJP_01910 1.9e-46 yktA S Belongs to the UPF0223 family
HKIJACJP_01911 1.3e-67 gtcA S Teichoic acid glycosylation protein
HKIJACJP_01912 1.4e-78 fld C Flavodoxin
HKIJACJP_01913 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
HKIJACJP_01914 1.6e-221 arcT 2.6.1.1 E Aminotransferase
HKIJACJP_01916 4.1e-55
HKIJACJP_01920 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HKIJACJP_01921 2.8e-224 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HKIJACJP_01922 2e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HKIJACJP_01923 1.2e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HKIJACJP_01924 3.6e-11
HKIJACJP_01925 3.7e-73
HKIJACJP_01926 6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKIJACJP_01927 5.3e-131 ponA V Beta-lactamase enzyme family
HKIJACJP_01928 2.8e-50 S amidohydrolase
HKIJACJP_01929 3.2e-259 K Aminotransferase class I and II
HKIJACJP_01930 2.2e-48 azlC E azaleucine resistance protein AzlC
HKIJACJP_01931 0.0 oppD EP Psort location Cytoplasmic, score
HKIJACJP_01932 1.2e-86 lytE M LysM domain protein
HKIJACJP_01933 3.9e-145 V ABC transporter, ATP-binding protein
HKIJACJP_01934 5.5e-116
HKIJACJP_01935 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HKIJACJP_01936 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
HKIJACJP_01937 5.1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKIJACJP_01938 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HKIJACJP_01940 1.5e-118 yrkL S Flavodoxin-like fold
HKIJACJP_01941 1.5e-52
HKIJACJP_01942 5.3e-16 S Domain of unknown function (DUF4767)
HKIJACJP_01943 4e-102 S C4-dicarboxylate anaerobic carrier
HKIJACJP_01944 2e-161 S C4-dicarboxylate anaerobic carrier
HKIJACJP_01945 1.9e-45 IQ Dehydrogenase reductase
HKIJACJP_01946 3.4e-76 S SIR2-like domain
HKIJACJP_01947 3.6e-249 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKIJACJP_01948 1.9e-19 cnrT EG PFAM EamA-like transporter family
HKIJACJP_01949 5.2e-17 cnrT EG PFAM EamA-like transporter family
HKIJACJP_01950 9.8e-51 S Domain of unknown function (DUF4430)
HKIJACJP_01951 5.9e-73 S ECF transporter, substrate-specific component
HKIJACJP_01973 2.6e-122 L Integrase core domain
HKIJACJP_01974 1.4e-109 L Bacterial dnaA protein
HKIJACJP_01975 1.5e-40 ltrA S Bacterial low temperature requirement A protein (LtrA)
HKIJACJP_01976 3.3e-37 ltrA S Bacterial low temperature requirement A protein (LtrA)
HKIJACJP_01977 1.5e-42 wecD3 K PFAM GCN5-related N-acetyltransferase
HKIJACJP_01978 4.3e-13
HKIJACJP_01979 8.2e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HKIJACJP_01980 5.2e-47 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HKIJACJP_01981 2e-274 pipD E Dipeptidase
HKIJACJP_01982 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKIJACJP_01983 6.6e-182 arsB 1.20.4.1 P Sodium Bile acid symporter family
HKIJACJP_01984 7.6e-31 L PFAM transposase IS200-family protein
HKIJACJP_01985 4.4e-59 azlC E azaleucine resistance protein AzlC
HKIJACJP_01986 3.2e-50 azlD E Branched-chain amino acid transport
HKIJACJP_01987 9.5e-113 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HKIJACJP_01989 5.2e-119 L hmm pf00665
HKIJACJP_01990 1.3e-94 L Helix-turn-helix domain
HKIJACJP_01991 2.7e-67 yqkB S Belongs to the HesB IscA family
HKIJACJP_01992 1.1e-25
HKIJACJP_01994 1.6e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HKIJACJP_01995 3.5e-45 polA_2 2.7.7.7 L DNA polymerase
HKIJACJP_01996 2.5e-70 S Psort location Cytoplasmic, score
HKIJACJP_01997 1.2e-42 polA_2 2.7.7.7 L DNA polymerase
HKIJACJP_01998 2.8e-69 S Psort location Cytoplasmic, score
HKIJACJP_01999 6.1e-25
HKIJACJP_02000 3.7e-190 G Peptidase_C39 like family
HKIJACJP_02001 5.1e-139 L Bacterial dnaA protein
HKIJACJP_02002 1.2e-174 L Integrase core domain
HKIJACJP_02004 2.5e-93 L Integrase
HKIJACJP_02006 1.3e-221 L COG3547 Transposase and inactivated derivatives
HKIJACJP_02007 1.1e-51 L Transposase IS200 like
HKIJACJP_02008 5.5e-185 L transposase, IS605 OrfB family
HKIJACJP_02009 1e-111 frnE Q DSBA-like thioredoxin domain
HKIJACJP_02010 9e-62 XK27_01125 L PFAM IS66 Orf2 family protein
HKIJACJP_02011 2e-149 S Phage plasmid primase, P4
HKIJACJP_02012 7.1e-46 S VRR_NUC
HKIJACJP_02013 8e-151 S Phage plasmid primase, P4
HKIJACJP_02014 2.1e-45 S VRR_NUC
HKIJACJP_02015 1.9e-84
HKIJACJP_02016 1e-66 L Uncharacterized conserved protein (DUF2075)
HKIJACJP_02017 1.6e-171 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKIJACJP_02018 5.8e-241 L PFAM Integrase catalytic region
HKIJACJP_02019 3.4e-11 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
HKIJACJP_02021 1.9e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKIJACJP_02022 4.6e-205 L Transposase IS66 family
HKIJACJP_02025 4.4e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HKIJACJP_02026 7.9e-70 L PFAM Integrase catalytic region
HKIJACJP_02027 5.4e-23 S helicase activity
HKIJACJP_02028 3e-98 xth 3.1.11.2 L exodeoxyribonuclease III
HKIJACJP_02030 3.7e-40 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKIJACJP_02031 9.2e-178 L PFAM Integrase catalytic region

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)