ORF_ID e_value Gene_name EC_number CAZy COGs Description
HOFAEECB_00001 3.3e-255 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HOFAEECB_00002 5.2e-08 3.4.22.70 M Sortase family
HOFAEECB_00003 1.7e-120 K helix_turn_helix, Lux Regulon
HOFAEECB_00004 1.9e-75
HOFAEECB_00005 4.5e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HOFAEECB_00006 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HOFAEECB_00007 4.6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HOFAEECB_00008 6.3e-47 3.4.23.43 S Type IV leader peptidase family
HOFAEECB_00009 7.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HOFAEECB_00010 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOFAEECB_00011 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOFAEECB_00012 1.1e-36
HOFAEECB_00013 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HOFAEECB_00014 1.6e-134 pgm3 G Phosphoglycerate mutase family
HOFAEECB_00015 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
HOFAEECB_00016 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HOFAEECB_00017 9e-126 lolD V ABC transporter
HOFAEECB_00018 1.1e-212 V FtsX-like permease family
HOFAEECB_00019 2.4e-63 S Domain of unknown function (DUF4418)
HOFAEECB_00020 0.0 pcrA 3.6.4.12 L DNA helicase
HOFAEECB_00021 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
HOFAEECB_00022 3e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HOFAEECB_00023 1.8e-240 pbuX F Permease family
HOFAEECB_00025 4.8e-45 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HOFAEECB_00026 1.7e-108 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HOFAEECB_00028 2.1e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
HOFAEECB_00029 9e-40
HOFAEECB_00030 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
HOFAEECB_00031 3.1e-121 tnp7109-21 L Integrase core domain
HOFAEECB_00032 1.3e-63 D MobA/MobL family
HOFAEECB_00033 1.6e-72
HOFAEECB_00035 1e-105 K helix_turn_helix, Arsenical Resistance Operon Repressor
HOFAEECB_00036 4.3e-245 EGP Major facilitator Superfamily
HOFAEECB_00037 1.6e-218 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HOFAEECB_00038 2.5e-165 L Excalibur calcium-binding domain
HOFAEECB_00039 3.9e-267 pepC 3.4.22.40 E Peptidase C1-like family
HOFAEECB_00040 4.7e-40 D nuclear chromosome segregation
HOFAEECB_00041 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HOFAEECB_00042 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HOFAEECB_00043 4.6e-188 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HOFAEECB_00044 0.0 yegQ O Peptidase family U32 C-terminal domain
HOFAEECB_00045 3e-56 L PFAM Integrase catalytic
HOFAEECB_00046 1.8e-220 L PFAM Integrase catalytic
HOFAEECB_00047 4.1e-144 L IstB-like ATP binding protein
HOFAEECB_00048 1e-158 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
HOFAEECB_00049 9.6e-175 L Transposase and inactivated derivatives IS30 family
HOFAEECB_00050 1.2e-89 L Transposase and inactivated derivatives IS30 family
HOFAEECB_00051 2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HOFAEECB_00052 1.1e-251 V ABC-2 family transporter protein
HOFAEECB_00053 9e-226 V ABC-2 family transporter protein
HOFAEECB_00054 6.3e-182 V ATPases associated with a variety of cellular activities
HOFAEECB_00055 1.2e-42 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HOFAEECB_00056 1.9e-234 T Histidine kinase
HOFAEECB_00057 3.1e-119 K helix_turn_helix, Lux Regulon
HOFAEECB_00058 1.1e-115 MA20_27875 P Protein of unknown function DUF47
HOFAEECB_00059 3.4e-189 pit P Phosphate transporter family
HOFAEECB_00060 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HOFAEECB_00061 3e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HOFAEECB_00062 1e-24
HOFAEECB_00063 2.1e-185
HOFAEECB_00064 1.1e-30 L Transposase
HOFAEECB_00065 4.9e-48 L Integrase core domain
HOFAEECB_00067 1.5e-191 S Protein of unknown function DUF262
HOFAEECB_00068 5.7e-118 S Protein of unknown function (DUF3800)
HOFAEECB_00069 1.3e-12
HOFAEECB_00070 1.2e-27
HOFAEECB_00071 7.4e-46 ysdA S Protein of unknown function (DUF1294)
HOFAEECB_00072 2.1e-52 ysdA S Protein of unknown function (DUF1294)
HOFAEECB_00075 3.8e-122
HOFAEECB_00076 8.2e-89 XK27_07020 S Domain of unknown function (DUF1846)
HOFAEECB_00077 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HOFAEECB_00078 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOFAEECB_00079 6.4e-276 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HOFAEECB_00080 3.6e-111 3.4.13.21 E Peptidase family S51
HOFAEECB_00081 6.5e-72 L Phage integrase family
HOFAEECB_00082 2.6e-52 L Phage integrase family
HOFAEECB_00084 2.1e-219 ykiI
HOFAEECB_00085 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HOFAEECB_00086 1.7e-123 3.6.1.13 L NUDIX domain
HOFAEECB_00087 3.6e-171 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HOFAEECB_00088 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOFAEECB_00089 9.2e-120 pdtaR T Response regulator receiver domain protein
HOFAEECB_00091 5.1e-110 aspA 3.6.1.13 L NUDIX domain
HOFAEECB_00092 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
HOFAEECB_00093 6.6e-179 terC P Integral membrane protein, TerC family
HOFAEECB_00094 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HOFAEECB_00095 4.5e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HOFAEECB_00096 3.6e-242 rpsA J Ribosomal protein S1
HOFAEECB_00097 2.6e-163 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HOFAEECB_00098 2.5e-173 P Zinc-uptake complex component A periplasmic
HOFAEECB_00099 5.3e-164 znuC P ATPases associated with a variety of cellular activities
HOFAEECB_00100 4.3e-139 znuB U ABC 3 transport family
HOFAEECB_00101 9.4e-83 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HOFAEECB_00102 5.1e-102 carD K CarD-like/TRCF domain
HOFAEECB_00103 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HOFAEECB_00104 1.9e-127 T Response regulator receiver domain protein
HOFAEECB_00105 5e-204 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HOFAEECB_00106 2.1e-72 rulA 3.4.21.88 KT Peptidase S24-like
HOFAEECB_00107 9e-130 ctsW S Phosphoribosyl transferase domain
HOFAEECB_00108 3.4e-157 cof 5.2.1.8 T Eukaryotic phosphomannomutase
HOFAEECB_00109 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HOFAEECB_00110 3.1e-265
HOFAEECB_00111 0.0 S Glycosyl transferase, family 2
HOFAEECB_00112 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HOFAEECB_00113 4.6e-269 K Cell envelope-related transcriptional attenuator domain
HOFAEECB_00114 0.0 D FtsK/SpoIIIE family
HOFAEECB_00115 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HOFAEECB_00116 7.3e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HOFAEECB_00117 2.6e-142 yplQ S Haemolysin-III related
HOFAEECB_00118 1.5e-106
HOFAEECB_00119 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOFAEECB_00120 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HOFAEECB_00121 8.8e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HOFAEECB_00122 6.1e-97
HOFAEECB_00124 1.2e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HOFAEECB_00125 5.7e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HOFAEECB_00126 2.5e-101 divIC D Septum formation initiator
HOFAEECB_00127 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOFAEECB_00128 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
HOFAEECB_00129 6.9e-297 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
HOFAEECB_00130 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOFAEECB_00131 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HOFAEECB_00132 7.3e-95 2.3.1.183 M Acetyltransferase (GNAT) domain
HOFAEECB_00133 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
HOFAEECB_00134 2.3e-150 GM ABC-2 type transporter
HOFAEECB_00135 1.9e-197 GM GDP-mannose 4,6 dehydratase
HOFAEECB_00136 2.4e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HOFAEECB_00138 3.1e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
HOFAEECB_00139 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOFAEECB_00140 5.6e-208 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HOFAEECB_00141 0.0 S Uncharacterised protein family (UPF0182)
HOFAEECB_00142 7.4e-231 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
HOFAEECB_00143 4.5e-197
HOFAEECB_00144 3e-153 ytrE V ATPases associated with a variety of cellular activities
HOFAEECB_00145 1.7e-191 V N-Acetylmuramoyl-L-alanine amidase
HOFAEECB_00146 4e-259 argE E Peptidase dimerisation domain
HOFAEECB_00147 4.2e-104 S Protein of unknown function (DUF3043)
HOFAEECB_00148 7.1e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HOFAEECB_00149 1.8e-142 S Domain of unknown function (DUF4191)
HOFAEECB_00150 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
HOFAEECB_00151 3.3e-18
HOFAEECB_00153 4.2e-19
HOFAEECB_00157 2e-160 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HOFAEECB_00158 5.7e-211 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HOFAEECB_00159 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOFAEECB_00160 0.0 S Tetratricopeptide repeat
HOFAEECB_00161 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOFAEECB_00162 7.5e-70 2.8.2.22 S Arylsulfotransferase Ig-like domain
HOFAEECB_00163 3.4e-138 bioM P ATPases associated with a variety of cellular activities
HOFAEECB_00164 2e-213 E Aminotransferase class I and II
HOFAEECB_00165 5.1e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
HOFAEECB_00166 4.3e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HOFAEECB_00167 0.0 ecfA GP ABC transporter, ATP-binding protein
HOFAEECB_00168 1.2e-256 EGP Major facilitator Superfamily
HOFAEECB_00169 2.2e-257 rarA L Recombination factor protein RarA
HOFAEECB_00170 0.0 L DEAD DEAH box helicase
HOFAEECB_00171 1.9e-192 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
HOFAEECB_00172 1.3e-199 gluD E Binding-protein-dependent transport system inner membrane component
HOFAEECB_00173 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
HOFAEECB_00174 4.3e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
HOFAEECB_00175 4.4e-138 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
HOFAEECB_00176 8.4e-84 S Aminoacyl-tRNA editing domain
HOFAEECB_00177 3.2e-81 K helix_turn_helix, Lux Regulon
HOFAEECB_00178 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HOFAEECB_00179 2.4e-264 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HOFAEECB_00180 6.6e-217 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HOFAEECB_00184 0.0 clpC O ATPase family associated with various cellular activities (AAA)
HOFAEECB_00185 1.8e-184 uspA T Belongs to the universal stress protein A family
HOFAEECB_00186 7.3e-192 S Protein of unknown function (DUF3027)
HOFAEECB_00187 5e-66 cspB K 'Cold-shock' DNA-binding domain
HOFAEECB_00188 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HOFAEECB_00189 1.6e-134 KT Response regulator receiver domain protein
HOFAEECB_00190 1.1e-158
HOFAEECB_00191 1.7e-10 S Proteins of 100 residues with WXG
HOFAEECB_00192 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HOFAEECB_00193 1.4e-30 cspA K 'Cold-shock' DNA-binding domain
HOFAEECB_00194 5.8e-71 S LytR cell envelope-related transcriptional attenuator
HOFAEECB_00195 1.1e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HOFAEECB_00196 1.3e-196 moxR S ATPase family associated with various cellular activities (AAA)
HOFAEECB_00197 1.7e-174 S Protein of unknown function DUF58
HOFAEECB_00198 1.1e-93
HOFAEECB_00199 8.4e-188 S von Willebrand factor (vWF) type A domain
HOFAEECB_00200 1.6e-148 S von Willebrand factor (vWF) type A domain
HOFAEECB_00201 7.2e-75
HOFAEECB_00203 3.5e-288 S PGAP1-like protein
HOFAEECB_00204 1.1e-280 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HOFAEECB_00205 0.0 S Lysylphosphatidylglycerol synthase TM region
HOFAEECB_00206 8.1e-42 hup L Belongs to the bacterial histone-like protein family
HOFAEECB_00207 7.2e-275 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HOFAEECB_00208 1.6e-10 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HOFAEECB_00209 2e-157 hisN 3.1.3.25 G Inositol monophosphatase family
HOFAEECB_00210 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HOFAEECB_00211 0.0 arc O AAA ATPase forming ring-shaped complexes
HOFAEECB_00212 6.6e-139 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HOFAEECB_00213 5.6e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOFAEECB_00214 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HOFAEECB_00215 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOFAEECB_00216 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOFAEECB_00217 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HOFAEECB_00218 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HOFAEECB_00219 4e-175 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HOFAEECB_00221 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HOFAEECB_00222 0.0 ctpE P E1-E2 ATPase
HOFAEECB_00223 2.3e-110
HOFAEECB_00224 2.5e-247 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOFAEECB_00225 7.5e-130 S Protein of unknown function (DUF3159)
HOFAEECB_00226 5.5e-139 S Protein of unknown function (DUF3710)
HOFAEECB_00227 5.3e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HOFAEECB_00228 4.2e-264 pepC 3.4.22.40 E Peptidase C1-like family
HOFAEECB_00229 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HOFAEECB_00230 0.0 oppD P Belongs to the ABC transporter superfamily
HOFAEECB_00231 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
HOFAEECB_00232 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
HOFAEECB_00233 4.7e-185 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HOFAEECB_00234 7.3e-42
HOFAEECB_00235 3.2e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HOFAEECB_00236 6.5e-198 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HOFAEECB_00237 8.4e-80
HOFAEECB_00238 0.0 typA T Elongation factor G C-terminus
HOFAEECB_00239 3.4e-236 iscS1 2.8.1.7 E Aminotransferase class-V
HOFAEECB_00240 5.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
HOFAEECB_00241 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HOFAEECB_00242 1.8e-250 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HOFAEECB_00243 5.6e-149 nrtR 3.6.1.55 F NUDIX hydrolase
HOFAEECB_00244 2.5e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HOFAEECB_00245 3.2e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HOFAEECB_00246 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HOFAEECB_00247 2.9e-179 xerD D recombinase XerD
HOFAEECB_00248 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HOFAEECB_00249 2.1e-25 rpmI J Ribosomal protein L35
HOFAEECB_00250 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HOFAEECB_00251 2.1e-07 S Spermine/spermidine synthase domain
HOFAEECB_00252 2.3e-133 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HOFAEECB_00253 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOFAEECB_00254 3.2e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOFAEECB_00256 2.2e-179 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HOFAEECB_00257 9.1e-194 galM 5.1.3.3 G Aldose 1-epimerase
HOFAEECB_00258 2e-64
HOFAEECB_00259 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HOFAEECB_00260 3e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOFAEECB_00261 6.8e-192 V Acetyltransferase (GNAT) domain
HOFAEECB_00262 2.7e-227 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
HOFAEECB_00263 8.9e-242 yxbA 6.3.1.12 S ATP-grasp
HOFAEECB_00264 8.6e-136 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HOFAEECB_00265 0.0 smc D Required for chromosome condensation and partitioning
HOFAEECB_00266 1.2e-281 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
HOFAEECB_00268 9.6e-97 3.6.1.55 F NUDIX domain
HOFAEECB_00269 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HOFAEECB_00270 0.0 P Belongs to the ABC transporter superfamily
HOFAEECB_00271 8.7e-191 dppC EP Binding-protein-dependent transport system inner membrane component
HOFAEECB_00272 2e-184 dppB EP Binding-protein-dependent transport system inner membrane component
HOFAEECB_00273 1.7e-304 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
HOFAEECB_00274 9.6e-244 nagA 3.5.1.25 G Amidohydrolase family
HOFAEECB_00275 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HOFAEECB_00276 1e-215 GK ROK family
HOFAEECB_00277 9.9e-132 cutC P Participates in the control of copper homeostasis
HOFAEECB_00278 3.1e-223 GK ROK family
HOFAEECB_00279 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
HOFAEECB_00280 1.3e-235 G Major Facilitator Superfamily
HOFAEECB_00281 1e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HOFAEECB_00283 1.3e-37
HOFAEECB_00284 4.7e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
HOFAEECB_00285 3.4e-294 murC 6.3.2.8 M Belongs to the MurCDEF family
HOFAEECB_00286 6.5e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HOFAEECB_00287 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HOFAEECB_00288 3.3e-264 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HOFAEECB_00289 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOFAEECB_00290 5.8e-283 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HOFAEECB_00291 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOFAEECB_00292 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HOFAEECB_00293 9.7e-64 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HOFAEECB_00294 1.6e-189 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HOFAEECB_00295 1.3e-90 mraZ K Belongs to the MraZ family
HOFAEECB_00296 0.0 L DNA helicase
HOFAEECB_00297 1.1e-228 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HOFAEECB_00298 1.1e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOFAEECB_00299 7.1e-49 M Lysin motif
HOFAEECB_00300 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HOFAEECB_00301 8.7e-165 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOFAEECB_00302 1.9e-175 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HOFAEECB_00303 2e-272 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HOFAEECB_00304 1.2e-171
HOFAEECB_00305 9.1e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HOFAEECB_00306 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HOFAEECB_00307 9.3e-176 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HOFAEECB_00308 1.1e-25 EGP Major facilitator Superfamily
HOFAEECB_00309 9.7e-250 S Domain of unknown function (DUF5067)
HOFAEECB_00310 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
HOFAEECB_00311 2.7e-282 S Uncharacterized protein conserved in bacteria (DUF2252)
HOFAEECB_00312 4.9e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HOFAEECB_00313 1.6e-120 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOFAEECB_00314 5.9e-113
HOFAEECB_00315 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HOFAEECB_00316 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOFAEECB_00317 7.1e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HOFAEECB_00318 5.1e-167 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HOFAEECB_00321 6.4e-75 yneG S Domain of unknown function (DUF4186)
HOFAEECB_00322 1.7e-173 dkgA 1.1.1.346 C Aldo/keto reductase family
HOFAEECB_00323 5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
HOFAEECB_00324 2.6e-202 K WYL domain
HOFAEECB_00327 0.0 4.2.1.53 S MCRA family
HOFAEECB_00328 2e-46 yhbY J CRS1_YhbY
HOFAEECB_00329 6.8e-99 S zinc-ribbon domain
HOFAEECB_00330 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HOFAEECB_00331 3e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HOFAEECB_00332 3.1e-19 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HOFAEECB_00333 5.1e-192 ywqG S Domain of unknown function (DUF1963)
HOFAEECB_00334 1.8e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOFAEECB_00335 7e-144 recO L Involved in DNA repair and RecF pathway recombination
HOFAEECB_00336 5.9e-294 I acetylesterase activity
HOFAEECB_00337 2.2e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HOFAEECB_00338 1.3e-221 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HOFAEECB_00339 2.8e-200 2.7.11.1 NU Tfp pilus assembly protein FimV
HOFAEECB_00341 1.4e-12 L PFAM Integrase catalytic
HOFAEECB_00342 4.7e-14
HOFAEECB_00343 3.2e-90
HOFAEECB_00345 1.9e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HOFAEECB_00346 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HOFAEECB_00347 2.7e-165 usp 3.5.1.28 CBM50 D CHAP domain protein
HOFAEECB_00348 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HOFAEECB_00349 3.7e-191 ftsE D Cell division ATP-binding protein FtsE
HOFAEECB_00350 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HOFAEECB_00351 2.6e-138 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HOFAEECB_00352 6e-63
HOFAEECB_00354 3.4e-177 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HOFAEECB_00355 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HOFAEECB_00356 9.7e-90 3.1.21.3 V DivIVA protein
HOFAEECB_00357 2.1e-42 yggT S YGGT family
HOFAEECB_00358 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HOFAEECB_00359 2.1e-230 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOFAEECB_00360 9.5e-247 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOFAEECB_00361 1.8e-300 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HOFAEECB_00362 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
HOFAEECB_00363 2.8e-157 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HOFAEECB_00364 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HOFAEECB_00365 1.3e-84
HOFAEECB_00366 2e-230 O AAA domain (Cdc48 subfamily)
HOFAEECB_00367 2.7e-163 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HOFAEECB_00368 4e-60 S Thiamine-binding protein
HOFAEECB_00369 3.5e-141 K helix_turn _helix lactose operon repressor
HOFAEECB_00370 1.7e-46 S Protein of unknown function (DUF3052)
HOFAEECB_00371 7.6e-152 lon T Belongs to the peptidase S16 family
HOFAEECB_00372 1.2e-288 S Zincin-like metallopeptidase
HOFAEECB_00373 1.7e-279 uvrD2 3.6.4.12 L DNA helicase
HOFAEECB_00374 4.6e-245 mphA S Aminoglycoside phosphotransferase
HOFAEECB_00375 6.1e-32 S Protein of unknown function (DUF3107)
HOFAEECB_00376 1.9e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
HOFAEECB_00377 7.6e-115 S Vitamin K epoxide reductase
HOFAEECB_00378 2.8e-168 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HOFAEECB_00379 3.9e-153 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HOFAEECB_00380 1.4e-168 S Patatin-like phospholipase
HOFAEECB_00381 0.0 V ABC transporter transmembrane region
HOFAEECB_00382 0.0 V ABC transporter, ATP-binding protein
HOFAEECB_00383 5.8e-89 K MarR family
HOFAEECB_00384 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
HOFAEECB_00385 1.9e-255 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
HOFAEECB_00386 1.3e-165
HOFAEECB_00387 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HOFAEECB_00389 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOFAEECB_00390 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HOFAEECB_00391 8.5e-273 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOFAEECB_00392 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOFAEECB_00393 6.2e-202 S Endonuclease/Exonuclease/phosphatase family
HOFAEECB_00396 8.1e-182 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HOFAEECB_00397 1.6e-252 cdr OP Sulfurtransferase TusA
HOFAEECB_00398 2.6e-149 moeB 2.7.7.80 H ThiF family
HOFAEECB_00399 5.4e-133 tmp1 S Domain of unknown function (DUF4391)
HOFAEECB_00400 6.9e-157 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HOFAEECB_00401 2.9e-229 aspB E Aminotransferase class-V
HOFAEECB_00402 2.5e-101 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HOFAEECB_00403 3.6e-271 S zinc finger
HOFAEECB_00404 8.8e-124 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOFAEECB_00405 3.2e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOFAEECB_00406 2.4e-290 O Subtilase family
HOFAEECB_00407 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
HOFAEECB_00408 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOFAEECB_00409 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOFAEECB_00410 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HOFAEECB_00411 7.4e-58 L Transposase
HOFAEECB_00412 6.4e-24 relB L RelB antitoxin
HOFAEECB_00413 2.7e-10 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HOFAEECB_00414 5.5e-42 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HOFAEECB_00415 1.1e-65 gsiA P ATPase activity
HOFAEECB_00416 1.7e-257 G Major Facilitator Superfamily
HOFAEECB_00417 6e-144 K -acetyltransferase
HOFAEECB_00418 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HOFAEECB_00419 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HOFAEECB_00420 4e-270 KLT Protein tyrosine kinase
HOFAEECB_00421 0.0 S Fibronectin type 3 domain
HOFAEECB_00422 2.7e-220 S ATPase family associated with various cellular activities (AAA)
HOFAEECB_00423 5.6e-226 S Protein of unknown function DUF58
HOFAEECB_00424 0.0 E Transglutaminase-like superfamily
HOFAEECB_00425 5.7e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
HOFAEECB_00426 3.1e-67 B Belongs to the OprB family
HOFAEECB_00427 8.5e-96 T Forkhead associated domain
HOFAEECB_00428 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFAEECB_00429 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFAEECB_00430 8.6e-103
HOFAEECB_00431 5.6e-183 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HOFAEECB_00432 7.6e-37 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
HOFAEECB_00433 1.3e-66 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
HOFAEECB_00434 2.4e-121 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HOFAEECB_00435 1.2e-185 S Membrane
HOFAEECB_00436 9.4e-253 S UPF0210 protein
HOFAEECB_00437 4.2e-43 gcvR T Belongs to the UPF0237 family
HOFAEECB_00438 8.6e-243 EGP Sugar (and other) transporter
HOFAEECB_00439 1.4e-44 S Psort location Cytoplasmic, score
HOFAEECB_00441 1.4e-21
HOFAEECB_00442 0.0 res 3.1.21.5 KL Type III restriction enzyme, res subunit
HOFAEECB_00443 8.2e-159 2.1.1.72 L DNA methylase
HOFAEECB_00444 1.5e-116 S filamentation induced by cAMP protein Fic
HOFAEECB_00446 2.7e-159 U Relaxase/Mobilisation nuclease domain
HOFAEECB_00447 6e-15 S Transposon-encoded protein TnpW
HOFAEECB_00448 4e-237 L Psort location Cytoplasmic, score
HOFAEECB_00449 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HOFAEECB_00450 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HOFAEECB_00451 8e-144 glpR K DeoR C terminal sensor domain
HOFAEECB_00452 5.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HOFAEECB_00453 4.3e-219 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
HOFAEECB_00454 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HOFAEECB_00455 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
HOFAEECB_00456 9.9e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HOFAEECB_00457 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HOFAEECB_00458 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HOFAEECB_00459 4.5e-239 S Uncharacterized conserved protein (DUF2183)
HOFAEECB_00460 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HOFAEECB_00461 0.0 enhA_2 S L,D-transpeptidase catalytic domain
HOFAEECB_00462 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HOFAEECB_00463 3.4e-160 mhpC I Alpha/beta hydrolase family
HOFAEECB_00464 1.5e-117 F Domain of unknown function (DUF4916)
HOFAEECB_00465 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HOFAEECB_00466 1.3e-179 S G5
HOFAEECB_00467 2.3e-226
HOFAEECB_00468 4.1e-41 L Psort location Cytoplasmic, score 8.87
HOFAEECB_00469 8.6e-115 L Integrase core domain
HOFAEECB_00470 6.8e-101 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HOFAEECB_00471 1.7e-304 EGP Major facilitator Superfamily
HOFAEECB_00472 3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HOFAEECB_00473 1.7e-122 L Protein of unknown function (DUF1524)
HOFAEECB_00474 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
HOFAEECB_00475 1.3e-202 K helix_turn _helix lactose operon repressor
HOFAEECB_00476 2.2e-113 G Glycosyl hydrolases family 43
HOFAEECB_00477 8.3e-120 G Glycosyl hydrolases family 43
HOFAEECB_00480 3.7e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HOFAEECB_00481 1.5e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HOFAEECB_00482 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HOFAEECB_00483 2.9e-10 fadD 6.2.1.3 I AMP-binding enzyme
HOFAEECB_00484 6.4e-207 K helix_turn _helix lactose operon repressor
HOFAEECB_00485 5.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOFAEECB_00486 1.8e-158 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HOFAEECB_00487 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HOFAEECB_00488 4.3e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HOFAEECB_00489 3.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HOFAEECB_00490 1.4e-292 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
HOFAEECB_00491 8.8e-213 gatC G PTS system sugar-specific permease component
HOFAEECB_00492 1.4e-173 K Putative sugar-binding domain
HOFAEECB_00494 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
HOFAEECB_00495 2.8e-274 abcT3 P ATPases associated with a variety of cellular activities
HOFAEECB_00496 5.9e-62 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
HOFAEECB_00497 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
HOFAEECB_00498 3e-120 mgtC S MgtC family
HOFAEECB_00500 6.9e-201
HOFAEECB_00502 1.5e-190
HOFAEECB_00503 0.0 pgi 5.3.1.9 G Belongs to the GPI family
HOFAEECB_00506 6.4e-174 S Auxin Efflux Carrier
HOFAEECB_00507 4.8e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOFAEECB_00508 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HOFAEECB_00509 1.3e-246 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOFAEECB_00511 7.6e-92 ilvN 2.2.1.6 E ACT domain
HOFAEECB_00512 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HOFAEECB_00513 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HOFAEECB_00514 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HOFAEECB_00515 2.3e-113 yceD S Uncharacterized ACR, COG1399
HOFAEECB_00516 3.6e-107
HOFAEECB_00517 1.7e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOFAEECB_00518 2e-58 S Protein of unknown function (DUF3039)
HOFAEECB_00519 0.0 yjjK S ABC transporter
HOFAEECB_00520 1.9e-135 guaA1 6.3.5.2 F Peptidase C26
HOFAEECB_00521 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOFAEECB_00522 1.4e-164 P Cation efflux family
HOFAEECB_00523 1.6e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOFAEECB_00524 2.8e-221 S Endonuclease/Exonuclease/phosphatase family
HOFAEECB_00525 2.2e-93 argO S LysE type translocator
HOFAEECB_00526 2.9e-295 ydfD EK Alanine-glyoxylate amino-transferase
HOFAEECB_00527 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HOFAEECB_00528 1.8e-34 CP_0960 S Belongs to the UPF0109 family
HOFAEECB_00529 1.9e-107 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOFAEECB_00530 1e-163 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HOFAEECB_00531 3.4e-82 hsp20 O Hsp20/alpha crystallin family
HOFAEECB_00532 4.1e-107 XK27_02070 S Nitroreductase family
HOFAEECB_00534 8.9e-122 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HOFAEECB_00535 9.9e-249 U Sodium:dicarboxylate symporter family
HOFAEECB_00536 0.0
HOFAEECB_00539 1.3e-219 steT E amino acid
HOFAEECB_00540 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
HOFAEECB_00541 1.4e-29 rpmB J Ribosomal L28 family
HOFAEECB_00542 6.5e-201 yegV G pfkB family carbohydrate kinase
HOFAEECB_00544 2.5e-242 yxiO S Vacuole effluxer Atg22 like
HOFAEECB_00545 4.2e-130 K helix_turn_helix, mercury resistance
HOFAEECB_00546 1.3e-08 T Toxic component of a toxin-antitoxin (TA) module
HOFAEECB_00547 3.7e-54 relB L RelB antitoxin
HOFAEECB_00548 3.8e-34 3.4.11.5 I carboxylic ester hydrolase activity
HOFAEECB_00549 7.1e-231 K Helix-turn-helix XRE-family like proteins
HOFAEECB_00550 1.5e-127 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
HOFAEECB_00555 2.4e-29
HOFAEECB_00557 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HOFAEECB_00558 2e-40 K Transcriptional regulator
HOFAEECB_00559 1.2e-67 S alpha beta
HOFAEECB_00561 4.5e-16
HOFAEECB_00562 1.8e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HOFAEECB_00563 5e-240 MA20_36090 S Psort location Cytoplasmic, score 8.87
HOFAEECB_00564 1.7e-119 K Bacterial regulatory proteins, tetR family
HOFAEECB_00565 1.8e-131 M Mechanosensitive ion channel
HOFAEECB_00566 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HOFAEECB_00567 3e-31 2.1.1.72 S Protein conserved in bacteria
HOFAEECB_00568 4.2e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HOFAEECB_00569 1.3e-68 S Domain of unknown function (DUF4854)
HOFAEECB_00570 2.2e-213 3.4.22.70 M Sortase family
HOFAEECB_00571 1.9e-276 M LPXTG cell wall anchor motif
HOFAEECB_00572 0.0 inlJ M domain protein
HOFAEECB_00573 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
HOFAEECB_00574 9.4e-147 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HOFAEECB_00575 5.1e-195 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOFAEECB_00576 5.3e-126 M Protein of unknown function (DUF3152)
HOFAEECB_00577 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HOFAEECB_00579 2.3e-35 E Domain of unknown function (DUF5011)
HOFAEECB_00580 5.4e-144 L IstB-like ATP binding protein
HOFAEECB_00581 1.8e-193 L PFAM Integrase catalytic
HOFAEECB_00582 9.7e-18 E Domain of unknown function (DUF5011)
HOFAEECB_00583 6.5e-46 S Parallel beta-helix repeats
HOFAEECB_00584 1.6e-15 S Parallel beta-helix repeats
HOFAEECB_00585 6.6e-70 rplI J Binds to the 23S rRNA
HOFAEECB_00586 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HOFAEECB_00587 1.1e-79 ssb1 L Single-stranded DNA-binding protein
HOFAEECB_00588 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HOFAEECB_00589 1.5e-163 T Pfam Adenylate and Guanylate cyclase catalytic domain
HOFAEECB_00590 1.9e-28
HOFAEECB_00591 8.8e-43
HOFAEECB_00592 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HOFAEECB_00593 3.4e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOFAEECB_00594 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
HOFAEECB_00595 3.7e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HOFAEECB_00596 3.4e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HOFAEECB_00597 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HOFAEECB_00598 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
HOFAEECB_00599 2.1e-117 nusG K Participates in transcription elongation, termination and antitermination
HOFAEECB_00600 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HOFAEECB_00602 2e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HOFAEECB_00603 1.5e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOFAEECB_00604 4.8e-299 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOFAEECB_00605 3.1e-214 K Psort location Cytoplasmic, score
HOFAEECB_00606 3.1e-40 rpmA J Ribosomal L27 protein
HOFAEECB_00607 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HOFAEECB_00608 0.0 rne 3.1.26.12 J Ribonuclease E/G family
HOFAEECB_00609 1.7e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
HOFAEECB_00610 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
HOFAEECB_00611 3.3e-256 V Efflux ABC transporter, permease protein
HOFAEECB_00612 1.1e-164 V ATPases associated with a variety of cellular activities
HOFAEECB_00613 2.1e-58
HOFAEECB_00614 1.9e-65
HOFAEECB_00615 4.4e-277 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HOFAEECB_00616 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HOFAEECB_00617 1.2e-239 hom 1.1.1.3 E Homoserine dehydrogenase
HOFAEECB_00618 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
HOFAEECB_00619 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HOFAEECB_00620 1.1e-305 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HOFAEECB_00621 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HOFAEECB_00622 6.8e-181 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HOFAEECB_00623 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
HOFAEECB_00624 2.2e-156 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
HOFAEECB_00625 9.2e-189 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOFAEECB_00626 2.8e-154 sapF E ATPases associated with a variety of cellular activities
HOFAEECB_00627 4e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
HOFAEECB_00628 5.8e-164 EP Binding-protein-dependent transport system inner membrane component
HOFAEECB_00629 1.4e-170 P Binding-protein-dependent transport system inner membrane component
HOFAEECB_00630 1.3e-309 E ABC transporter, substrate-binding protein, family 5
HOFAEECB_00631 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HOFAEECB_00632 2.2e-276 G Bacterial extracellular solute-binding protein
HOFAEECB_00633 7.9e-64 G carbohydrate transport
HOFAEECB_00634 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HOFAEECB_00635 6.5e-125 G ABC transporter permease
HOFAEECB_00636 2.9e-190 K Periplasmic binding protein domain
HOFAEECB_00637 6.5e-20 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HOFAEECB_00638 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
HOFAEECB_00640 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HOFAEECB_00641 5e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HOFAEECB_00642 9.3e-275 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
HOFAEECB_00643 5.6e-124 XK27_08050 O prohibitin homologues
HOFAEECB_00644 4.5e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
HOFAEECB_00645 2e-233 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HOFAEECB_00646 3.1e-259 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
HOFAEECB_00647 9.9e-225 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HOFAEECB_00648 0.0 macB_2 V ATPases associated with a variety of cellular activities
HOFAEECB_00649 0.0 ctpE P E1-E2 ATPase
HOFAEECB_00650 2.4e-197 yghZ C Aldo/keto reductase family
HOFAEECB_00651 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HOFAEECB_00652 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HOFAEECB_00653 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
HOFAEECB_00654 2.6e-121 S Short repeat of unknown function (DUF308)
HOFAEECB_00655 0.0 pepO 3.4.24.71 O Peptidase family M13
HOFAEECB_00656 1.5e-118 L Single-strand binding protein family
HOFAEECB_00657 2.4e-170
HOFAEECB_00658 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HOFAEECB_00659 7.9e-185 phoN I PAP2 superfamily
HOFAEECB_00660 7.4e-39 GT87 NU Tfp pilus assembly protein FimV
HOFAEECB_00661 9.7e-269 recD2 3.6.4.12 L PIF1-like helicase
HOFAEECB_00662 4e-161 supH S Sucrose-6F-phosphate phosphohydrolase
HOFAEECB_00663 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HOFAEECB_00664 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HOFAEECB_00665 3.5e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HOFAEECB_00666 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HOFAEECB_00667 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
HOFAEECB_00668 2.1e-54 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HOFAEECB_00669 2.5e-186 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HOFAEECB_00670 2.6e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HOFAEECB_00671 3.9e-36 rpmE J Binds the 23S rRNA
HOFAEECB_00673 3.8e-193 K helix_turn_helix, arabinose operon control protein
HOFAEECB_00674 1.3e-162 glcU G Sugar transport protein
HOFAEECB_00675 2.2e-177 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HOFAEECB_00676 5.1e-256 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
HOFAEECB_00677 2.8e-107
HOFAEECB_00678 5.4e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
HOFAEECB_00679 1.4e-140 3.5.2.6 V Beta-lactamase enzyme family
HOFAEECB_00680 7.4e-307 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HOFAEECB_00681 4.2e-164 EG EamA-like transporter family
HOFAEECB_00682 4.8e-141 V FtsX-like permease family
HOFAEECB_00683 4.4e-147 S Sulfite exporter TauE/SafE
HOFAEECB_00685 6.4e-215 MA20_36090 S Psort location Cytoplasmic, score 8.87
HOFAEECB_00686 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
HOFAEECB_00687 6.5e-44 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
HOFAEECB_00688 2.6e-72 EGP Major facilitator superfamily
HOFAEECB_00689 3.7e-179 glkA 2.7.1.2 G ROK family
HOFAEECB_00690 3.7e-301 S ATPases associated with a variety of cellular activities
HOFAEECB_00691 4.6e-55 EGP Major facilitator Superfamily
HOFAEECB_00692 2.4e-158 I alpha/beta hydrolase fold
HOFAEECB_00693 6.5e-116 S Pyridoxamine 5'-phosphate oxidase
HOFAEECB_00695 1.7e-48 S DUF218 domain
HOFAEECB_00696 2.6e-108 S Protein of unknown function (DUF969)
HOFAEECB_00697 3e-157 S Protein of unknown function (DUF979)
HOFAEECB_00698 3.7e-114 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HOFAEECB_00700 5.7e-126
HOFAEECB_00701 2.9e-162 M domain, Protein
HOFAEECB_00702 4e-19 M domain, Protein
HOFAEECB_00703 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
HOFAEECB_00704 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
HOFAEECB_00705 7.1e-172 tesB I Thioesterase-like superfamily
HOFAEECB_00706 1.3e-77 S Protein of unknown function (DUF3180)
HOFAEECB_00707 2.7e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HOFAEECB_00708 6.2e-165 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HOFAEECB_00709 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HOFAEECB_00710 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOFAEECB_00711 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HOFAEECB_00712 2.3e-212 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HOFAEECB_00713 5.3e-262 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
HOFAEECB_00714 2.3e-309
HOFAEECB_00715 1.7e-168 natA V ATPases associated with a variety of cellular activities
HOFAEECB_00716 1.3e-232 epsG M Glycosyl transferase family 21
HOFAEECB_00717 3.9e-274 S AI-2E family transporter
HOFAEECB_00718 1.9e-177 3.4.14.13 M Glycosyltransferase like family 2
HOFAEECB_00719 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
HOFAEECB_00722 3.5e-65 S Domain of unknown function (DUF4190)
HOFAEECB_00723 2.6e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HOFAEECB_00724 2.3e-153 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HOFAEECB_00726 3.4e-11
HOFAEECB_00727 2.2e-21
HOFAEECB_00728 1.6e-232 S Helix-turn-helix domain
HOFAEECB_00729 4e-82 S Transcription factor WhiB
HOFAEECB_00730 4.6e-103 parA D AAA domain
HOFAEECB_00731 1.7e-35
HOFAEECB_00732 9.2e-71
HOFAEECB_00733 1.2e-26
HOFAEECB_00734 7.8e-126 K Helix-turn-helix domain protein
HOFAEECB_00736 0.0 sprF 4.6.1.1 M Cell surface antigen C-terminus
HOFAEECB_00737 4.9e-47 V ABC-2 type transporter
HOFAEECB_00738 9.6e-41 V ATPase activity
HOFAEECB_00739 3.2e-18 V Lanthionine synthetase C-like protein
HOFAEECB_00741 6.8e-81
HOFAEECB_00742 2.2e-99
HOFAEECB_00743 2e-120 V ATPases associated with a variety of cellular activities
HOFAEECB_00744 1.9e-98 lacR K Transcriptional regulator, LacI family
HOFAEECB_00745 6.4e-227 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HOFAEECB_00746 3.9e-119 K Transcriptional regulatory protein, C terminal
HOFAEECB_00748 2.2e-95
HOFAEECB_00749 3.2e-179 V N-Acetylmuramoyl-L-alanine amidase
HOFAEECB_00750 8.2e-108 ytrE V ABC transporter
HOFAEECB_00751 6.6e-172
HOFAEECB_00752 1.2e-11 S Psort location CytoplasmicMembrane, score 9.99
HOFAEECB_00753 1.4e-219 vex3 V ABC transporter permease
HOFAEECB_00754 9.5e-212 vex1 V Efflux ABC transporter, permease protein
HOFAEECB_00755 4.1e-110 vex2 V ABC transporter, ATP-binding protein
HOFAEECB_00756 9.8e-49 azlD E Branched-chain amino acid transport protein (AzlD)
HOFAEECB_00757 3.1e-195 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
HOFAEECB_00758 2.1e-96 ptpA 3.1.3.48 T low molecular weight
HOFAEECB_00759 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
HOFAEECB_00760 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOFAEECB_00761 2.9e-72 attW O OsmC-like protein
HOFAEECB_00762 1.6e-191 T Universal stress protein family
HOFAEECB_00763 2.4e-107 M NlpC/P60 family
HOFAEECB_00764 1.1e-181 usp 3.5.1.28 CBM50 S CHAP domain
HOFAEECB_00765 7.5e-214 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HOFAEECB_00766 2.6e-39
HOFAEECB_00767 2.9e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HOFAEECB_00768 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
HOFAEECB_00769 9.4e-11 EGP Major facilitator Superfamily
HOFAEECB_00770 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOFAEECB_00771 9.5e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HOFAEECB_00772 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HOFAEECB_00774 4.3e-217 araJ EGP Major facilitator Superfamily
HOFAEECB_00775 0.0 S Domain of unknown function (DUF4037)
HOFAEECB_00776 1.6e-111 S Protein of unknown function (DUF4125)
HOFAEECB_00777 3.2e-130
HOFAEECB_00778 2.2e-283 pspC KT PspC domain
HOFAEECB_00779 1.5e-264 tcsS3 KT PspC domain
HOFAEECB_00780 9.2e-126 degU K helix_turn_helix, Lux Regulon
HOFAEECB_00781 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOFAEECB_00782 1.7e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HOFAEECB_00783 1.2e-185 opcA G Glucose-6-phosphate dehydrogenase subunit
HOFAEECB_00784 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HOFAEECB_00785 2.6e-94
HOFAEECB_00787 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
HOFAEECB_00789 4e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOFAEECB_00790 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
HOFAEECB_00791 5.1e-212 I Diacylglycerol kinase catalytic domain
HOFAEECB_00792 7.6e-152 arbG K CAT RNA binding domain
HOFAEECB_00793 0.0 crr G pts system, glucose-specific IIABC component
HOFAEECB_00794 5e-26 M Spy0128-like isopeptide containing domain
HOFAEECB_00795 1.8e-72 M Spy0128-like isopeptide containing domain
HOFAEECB_00797 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HOFAEECB_00798 3.4e-261 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HOFAEECB_00799 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
HOFAEECB_00800 2.1e-202 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOFAEECB_00801 1.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HOFAEECB_00803 1.2e-104
HOFAEECB_00804 6.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOFAEECB_00805 1.6e-230 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HOFAEECB_00806 4e-229 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HOFAEECB_00807 1e-83 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HOFAEECB_00808 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HOFAEECB_00809 2.8e-188 nusA K Participates in both transcription termination and antitermination
HOFAEECB_00810 2.5e-159
HOFAEECB_00811 2.1e-87 L Transposase and inactivated derivatives
HOFAEECB_00813 1.3e-153 E Transglutaminase/protease-like homologues
HOFAEECB_00814 0.0 gcs2 S A circularly permuted ATPgrasp
HOFAEECB_00815 9.2e-172 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HOFAEECB_00816 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
HOFAEECB_00817 2.8e-64 rplQ J Ribosomal protein L17
HOFAEECB_00818 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFAEECB_00819 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOFAEECB_00820 7.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOFAEECB_00821 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HOFAEECB_00822 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOFAEECB_00823 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HOFAEECB_00824 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HOFAEECB_00825 2.7e-63 rplO J binds to the 23S rRNA
HOFAEECB_00826 1e-24 rpmD J Ribosomal protein L30p/L7e
HOFAEECB_00827 6.5e-99 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HOFAEECB_00828 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HOFAEECB_00829 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOFAEECB_00830 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HOFAEECB_00831 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOFAEECB_00832 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOFAEECB_00833 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HOFAEECB_00834 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HOFAEECB_00835 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOFAEECB_00836 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
HOFAEECB_00837 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HOFAEECB_00838 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOFAEECB_00839 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOFAEECB_00840 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOFAEECB_00841 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOFAEECB_00842 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HOFAEECB_00843 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
HOFAEECB_00844 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOFAEECB_00845 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
HOFAEECB_00846 1.1e-20 ywiC S YwiC-like protein
HOFAEECB_00847 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HOFAEECB_00848 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HOFAEECB_00849 1.2e-230 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HOFAEECB_00850 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HOFAEECB_00851 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
HOFAEECB_00852 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HOFAEECB_00853 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HOFAEECB_00854 2.4e-112
HOFAEECB_00855 3.1e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HOFAEECB_00856 2.2e-254 M Bacterial capsule synthesis protein PGA_cap
HOFAEECB_00858 9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOFAEECB_00859 4.7e-224 dapC E Aminotransferase class I and II
HOFAEECB_00860 9e-61 fdxA C 4Fe-4S binding domain
HOFAEECB_00861 6.9e-215 murB 1.3.1.98 M Cell wall formation
HOFAEECB_00862 1.9e-25 rpmG J Ribosomal protein L33
HOFAEECB_00866 6.9e-44 KLT Associated with various cellular activities
HOFAEECB_00867 1.4e-128 bla1 3.5.2.6 V Beta-lactamase enzyme family
HOFAEECB_00868 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HOFAEECB_00869 1.5e-130
HOFAEECB_00870 2e-93 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
HOFAEECB_00871 1.2e-120 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HOFAEECB_00872 3.2e-38 fmdB S Putative regulatory protein
HOFAEECB_00873 5.6e-110 flgA NO SAF
HOFAEECB_00874 2.8e-41
HOFAEECB_00875 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HOFAEECB_00876 9.1e-242 T Forkhead associated domain
HOFAEECB_00878 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HOFAEECB_00879 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOFAEECB_00880 3.5e-180 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
HOFAEECB_00881 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
HOFAEECB_00883 8.8e-222 pbuO S Permease family
HOFAEECB_00884 5.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HOFAEECB_00885 2.5e-169 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HOFAEECB_00886 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOFAEECB_00887 3.1e-179 pstA P Phosphate transport system permease
HOFAEECB_00888 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
HOFAEECB_00889 2.3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HOFAEECB_00890 3.7e-128 KT Transcriptional regulatory protein, C terminal
HOFAEECB_00891 2e-242 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HOFAEECB_00892 1.2e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOFAEECB_00893 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HOFAEECB_00894 1.1e-192 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOFAEECB_00895 2.1e-108
HOFAEECB_00896 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
HOFAEECB_00897 0.0 pknL 2.7.11.1 KLT PASTA
HOFAEECB_00898 5.7e-200 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
HOFAEECB_00899 8.5e-122
HOFAEECB_00900 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HOFAEECB_00901 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HOFAEECB_00902 2.9e-276 aspA 4.3.1.1 E Fumarase C C-terminus
HOFAEECB_00903 3.2e-15 K Transcriptional regulator
HOFAEECB_00904 3e-25 yozG K Cro/C1-type HTH DNA-binding domain
HOFAEECB_00905 0.0 lhr L DEAD DEAH box helicase
HOFAEECB_00906 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HOFAEECB_00907 6.5e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
HOFAEECB_00908 2e-173 S Protein of unknown function (DUF3071)
HOFAEECB_00909 1.4e-47 S Domain of unknown function (DUF4193)
HOFAEECB_00910 5e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HOFAEECB_00911 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOFAEECB_00912 2.7e-28
HOFAEECB_00913 1.4e-12
HOFAEECB_00914 9.6e-208 E Belongs to the peptidase S1B family
HOFAEECB_00915 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
HOFAEECB_00916 1.1e-49 relB L RelB antitoxin
HOFAEECB_00917 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOFAEECB_00918 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
HOFAEECB_00919 2.6e-83 P ABC-type metal ion transport system permease component
HOFAEECB_00920 1.3e-223 S Peptidase dimerisation domain
HOFAEECB_00921 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HOFAEECB_00922 1.2e-38
HOFAEECB_00923 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HOFAEECB_00924 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOFAEECB_00925 4.4e-114 S Protein of unknown function (DUF3000)
HOFAEECB_00926 5.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
HOFAEECB_00927 2.6e-234 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HOFAEECB_00928 2.7e-247 clcA_2 P Voltage gated chloride channel
HOFAEECB_00929 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOFAEECB_00930 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOFAEECB_00931 2e-244 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HOFAEECB_00934 1.9e-233 patB 4.4.1.8 E Aminotransferase, class I II
HOFAEECB_00935 1.6e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HOFAEECB_00936 3.9e-165 fmt2 3.2.2.10 S Belongs to the LOG family
HOFAEECB_00937 5.7e-118 safC S O-methyltransferase
HOFAEECB_00938 6.6e-184 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
HOFAEECB_00939 3e-71 yraN L Belongs to the UPF0102 family
HOFAEECB_00940 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
HOFAEECB_00941 8.8e-284 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HOFAEECB_00942 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HOFAEECB_00943 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HOFAEECB_00944 4.6e-157 S Putative ABC-transporter type IV
HOFAEECB_00945 4.5e-252 metY 2.5.1.49 E Aminotransferase class-V
HOFAEECB_00946 1e-161 V ABC transporter, ATP-binding protein
HOFAEECB_00947 0.0 MV MacB-like periplasmic core domain
HOFAEECB_00948 0.0 phoN I PAP2 superfamily
HOFAEECB_00949 7.9e-132 K helix_turn_helix, Lux Regulon
HOFAEECB_00950 0.0 tcsS2 T Histidine kinase
HOFAEECB_00951 1.9e-264 pip 3.4.11.5 S alpha/beta hydrolase fold
HOFAEECB_00952 3.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOFAEECB_00953 2.3e-165 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
HOFAEECB_00954 3.5e-146 P NLPA lipoprotein
HOFAEECB_00955 1e-187 acoA 1.2.4.1 C Dehydrogenase E1 component
HOFAEECB_00956 7.8e-183 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
HOFAEECB_00957 3.4e-203 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOFAEECB_00958 3.8e-93 metI P Binding-protein-dependent transport system inner membrane component
HOFAEECB_00959 1.7e-229 mtnE 2.6.1.83 E Aminotransferase class I and II
HOFAEECB_00960 2.3e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HOFAEECB_00961 2.1e-62 2.1.1.113, 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HOFAEECB_00962 3.6e-195 mod 2.1.1.72 L PFAM DNA methylase
HOFAEECB_00963 5.4e-244 3.1.21.5 L Type III restriction enzyme res subunit
HOFAEECB_00964 2.9e-61 J tRNA cytidylyltransferase activity
HOFAEECB_00965 1.6e-12 yjcD 3.6.4.12 L UvrD-like helicase C-terminal domain
HOFAEECB_00968 3.9e-90
HOFAEECB_00969 4.8e-246 XK27_00240 K Fic/DOC family
HOFAEECB_00970 8.6e-120 E Psort location Cytoplasmic, score 8.87
HOFAEECB_00971 5.6e-59 yccF S Inner membrane component domain
HOFAEECB_00972 2.8e-157 ksgA 2.1.1.182 J Methyltransferase domain
HOFAEECB_00973 9.7e-63 S Cupin 2, conserved barrel domain protein
HOFAEECB_00974 1.1e-255 KLT Protein tyrosine kinase
HOFAEECB_00975 4.5e-79 K Psort location Cytoplasmic, score
HOFAEECB_00976 1.5e-148
HOFAEECB_00977 2.7e-22
HOFAEECB_00978 1.5e-196 S Short C-terminal domain
HOFAEECB_00979 2.7e-87 S Helix-turn-helix
HOFAEECB_00980 2.8e-66 S Zincin-like metallopeptidase
HOFAEECB_00982 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HOFAEECB_00983 1.9e-24
HOFAEECB_00984 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HOFAEECB_00985 2.3e-124 ypfH S Phospholipase/Carboxylesterase
HOFAEECB_00986 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HOFAEECB_00988 3.2e-289 2.4.1.166 GT2 M Glycosyltransferase like family 2
HOFAEECB_00989 4.2e-118 3.1.3.27 E haloacid dehalogenase-like hydrolase
HOFAEECB_00990 1.9e-144 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
HOFAEECB_00991 2e-186 MA20_14895 S Conserved hypothetical protein 698
HOFAEECB_00992 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
HOFAEECB_00993 1.4e-237 rutG F Permease family
HOFAEECB_00994 3.7e-76 K AraC-like ligand binding domain
HOFAEECB_00996 3e-53 IQ oxidoreductase activity
HOFAEECB_00997 1.2e-135 ybbM V Uncharacterised protein family (UPF0014)
HOFAEECB_00998 1.7e-134 ybbL V ATPases associated with a variety of cellular activities
HOFAEECB_00999 1.6e-160 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOFAEECB_01000 7e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HOFAEECB_01001 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HOFAEECB_01002 5.1e-87
HOFAEECB_01003 2.2e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HOFAEECB_01004 7.9e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HOFAEECB_01005 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HOFAEECB_01006 2.5e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HOFAEECB_01007 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HOFAEECB_01008 1.4e-84 argR K Regulates arginine biosynthesis genes
HOFAEECB_01009 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HOFAEECB_01010 2.3e-50 3.1.21.3 V Type I restriction modification DNA specificity domain
HOFAEECB_01011 1e-178 L Phage integrase family
HOFAEECB_01012 2.4e-30
HOFAEECB_01013 6.5e-156 S Domain of unknown function (DUF4357)
HOFAEECB_01014 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
HOFAEECB_01015 3.2e-114 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
HOFAEECB_01016 4.3e-270 3.6.4.12 K Putative DNA-binding domain
HOFAEECB_01017 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HOFAEECB_01018 1.8e-281 argH 4.3.2.1 E argininosuccinate lyase
HOFAEECB_01019 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HOFAEECB_01020 1.6e-143 S Putative ABC-transporter type IV
HOFAEECB_01021 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOFAEECB_01022 1.8e-158 L Tetratricopeptide repeat
HOFAEECB_01023 2.3e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HOFAEECB_01025 1.4e-136 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HOFAEECB_01026 2.9e-101
HOFAEECB_01027 6.8e-116 trkA P TrkA-N domain
HOFAEECB_01028 3.9e-236 trkB P Cation transport protein
HOFAEECB_01029 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOFAEECB_01030 9.2e-293 recN L May be involved in recombinational repair of damaged DNA
HOFAEECB_01031 3.4e-123 S Haloacid dehalogenase-like hydrolase
HOFAEECB_01032 6.3e-58 K helix_turn_helix gluconate operon transcriptional repressor
HOFAEECB_01033 9.5e-175 V ATPases associated with a variety of cellular activities
HOFAEECB_01034 3.7e-126 S ABC-2 family transporter protein
HOFAEECB_01035 8.1e-123 S ABC-2 family transporter protein
HOFAEECB_01036 1.7e-284 thrC 4.2.3.1 E Threonine synthase N terminus
HOFAEECB_01037 5.3e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HOFAEECB_01038 2.3e-93
HOFAEECB_01039 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOFAEECB_01040 2e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOFAEECB_01042 1.6e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOFAEECB_01043 1.2e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HOFAEECB_01044 6e-137 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HOFAEECB_01045 2.5e-77 S Bacterial PH domain
HOFAEECB_01046 2.3e-253 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
HOFAEECB_01048 7.5e-108
HOFAEECB_01049 2.5e-132 C Putative TM nitroreductase
HOFAEECB_01050 4.5e-142 yijF S Domain of unknown function (DUF1287)
HOFAEECB_01051 2.7e-70 pdxH S Pfam:Pyridox_oxidase
HOFAEECB_01052 1.1e-53 KT RESPONSE REGULATOR receiver
HOFAEECB_01053 2.2e-193 V VanZ like family
HOFAEECB_01054 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
HOFAEECB_01055 6.6e-96 ypjC S Putative ABC-transporter type IV
HOFAEECB_01056 7.5e-158
HOFAEECB_01058 8.9e-101 EGP Major facilitator Superfamily
HOFAEECB_01059 3e-28 EGP Major facilitator Superfamily
HOFAEECB_01060 2.4e-162 rpoC M heme binding
HOFAEECB_01061 1.1e-78 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOFAEECB_01062 1.3e-30
HOFAEECB_01063 1.1e-40
HOFAEECB_01064 1.4e-132 S SOS response associated peptidase (SRAP)
HOFAEECB_01065 3.6e-74 qseC 2.7.13.3 T Histidine kinase
HOFAEECB_01066 5.9e-185 S Acetyltransferase (GNAT) domain
HOFAEECB_01068 2.7e-90 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
HOFAEECB_01069 4.1e-33 K Transcriptional regulator
HOFAEECB_01070 2.2e-90 MA20_25245 K FR47-like protein
HOFAEECB_01071 3.5e-125 ydaF_1 J Acetyltransferase (GNAT) domain
HOFAEECB_01072 7.6e-64 yeaO K Protein of unknown function, DUF488
HOFAEECB_01073 2.4e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HOFAEECB_01074 5.7e-283 S Psort location Cytoplasmic, score 8.87
HOFAEECB_01075 1.8e-110 S Domain of unknown function (DUF4194)
HOFAEECB_01076 0.0 S Psort location Cytoplasmic, score 8.87
HOFAEECB_01077 4.5e-299 E Serine carboxypeptidase
HOFAEECB_01078 3.6e-162 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HOFAEECB_01079 4.8e-171 corA P CorA-like Mg2+ transporter protein
HOFAEECB_01080 2.9e-168 ET Bacterial periplasmic substrate-binding proteins
HOFAEECB_01081 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOFAEECB_01082 4.4e-88 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
HOFAEECB_01083 0.0 comE S Competence protein
HOFAEECB_01084 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
HOFAEECB_01085 1.7e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
HOFAEECB_01086 1.1e-158 yeaZ 2.3.1.234 O Glycoprotease family
HOFAEECB_01087 1.2e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
HOFAEECB_01088 1.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOFAEECB_01090 2.5e-132 M Peptidase family M23
HOFAEECB_01091 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
HOFAEECB_01092 7.9e-275 G ABC transporter substrate-binding protein
HOFAEECB_01093 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HOFAEECB_01094 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
HOFAEECB_01095 3.4e-91
HOFAEECB_01096 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
HOFAEECB_01097 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOFAEECB_01098 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HOFAEECB_01099 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HOFAEECB_01100 1e-127 3.2.1.8 S alpha beta
HOFAEECB_01101 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HOFAEECB_01102 8.9e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HOFAEECB_01103 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
HOFAEECB_01104 4.1e-228 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HOFAEECB_01105 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HOFAEECB_01106 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HOFAEECB_01107 7.9e-307 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOFAEECB_01108 2.9e-243 G Bacterial extracellular solute-binding protein
HOFAEECB_01109 1.1e-173 G Binding-protein-dependent transport system inner membrane component
HOFAEECB_01110 5e-168 G ABC transporter permease
HOFAEECB_01111 4.2e-181 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
HOFAEECB_01112 1.1e-45
HOFAEECB_01113 6e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HOFAEECB_01114 7.1e-64 S Protein of unknown function (DUF4235)
HOFAEECB_01115 7e-138 G Phosphoglycerate mutase family
HOFAEECB_01117 1.6e-188 K Psort location Cytoplasmic, score
HOFAEECB_01118 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
HOFAEECB_01119 0.0 dnaK O Heat shock 70 kDa protein
HOFAEECB_01120 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOFAEECB_01121 1.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
HOFAEECB_01122 5.2e-87 hspR K transcriptional regulator, MerR family
HOFAEECB_01123 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
HOFAEECB_01124 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
HOFAEECB_01125 1.8e-133 S HAD hydrolase, family IA, variant 3
HOFAEECB_01127 3.5e-126 dedA S SNARE associated Golgi protein
HOFAEECB_01128 7.5e-167 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOFAEECB_01129 8.6e-59
HOFAEECB_01130 3.6e-130
HOFAEECB_01131 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOFAEECB_01132 7.8e-83 K Transcriptional regulator
HOFAEECB_01134 1.1e-262 xylR 5.3.1.12 G MFS/sugar transport protein
HOFAEECB_01135 3.8e-184 tatD L TatD related DNase
HOFAEECB_01136 0.0 kup P Transport of potassium into the cell
HOFAEECB_01138 3e-164 S Glutamine amidotransferase domain
HOFAEECB_01139 4.6e-137 T HD domain
HOFAEECB_01140 3e-179 V ABC transporter
HOFAEECB_01141 1.4e-246 V ABC transporter permease
HOFAEECB_01142 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
HOFAEECB_01143 0.0 S Psort location Cytoplasmic, score 8.87
HOFAEECB_01144 5.4e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HOFAEECB_01145 3.3e-26 thiS 2.8.1.10 H ThiS family
HOFAEECB_01146 3.3e-275
HOFAEECB_01147 1.9e-208 S Glycosyltransferase, group 2 family protein
HOFAEECB_01148 5.7e-29 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HOFAEECB_01149 1.3e-16 cbiM P PDGLE domain
HOFAEECB_01150 8.6e-91
HOFAEECB_01151 1.2e-221 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HOFAEECB_01152 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HOFAEECB_01154 2.6e-152 cpaE D bacterial-type flagellum organization
HOFAEECB_01155 3.4e-191 cpaF U Type II IV secretion system protein
HOFAEECB_01156 5.1e-122 U Type ii secretion system
HOFAEECB_01157 8.3e-15 gspF NU Type II secretion system (T2SS), protein F
HOFAEECB_01158 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
HOFAEECB_01159 1.9e-41 S Protein of unknown function (DUF4244)
HOFAEECB_01160 6.9e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
HOFAEECB_01161 3.7e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
HOFAEECB_01162 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HOFAEECB_01163 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOFAEECB_01164 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HOFAEECB_01165 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
HOFAEECB_01167 2.6e-213 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOFAEECB_01168 1.7e-116
HOFAEECB_01169 2.3e-284 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HOFAEECB_01170 2.3e-15 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
HOFAEECB_01171 3e-278 S Calcineurin-like phosphoesterase
HOFAEECB_01172 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOFAEECB_01173 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HOFAEECB_01174 7.1e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
HOFAEECB_01175 4e-122 yplQ S Haemolysin-III related
HOFAEECB_01176 0.0 vpr M PA domain
HOFAEECB_01177 8e-189 3.6.1.27 I PAP2 superfamily
HOFAEECB_01178 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOFAEECB_01179 2.1e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HOFAEECB_01180 1.4e-212 holB 2.7.7.7 L DNA polymerase III
HOFAEECB_01181 4.4e-200 K helix_turn _helix lactose operon repressor
HOFAEECB_01182 5e-38 ptsH G PTS HPr component phosphorylation site
HOFAEECB_01183 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOFAEECB_01184 1.5e-50 S Fic/DOC family
HOFAEECB_01185 6.1e-38 S Fic/DOC family
HOFAEECB_01186 1.4e-195 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HOFAEECB_01187 2.8e-33 L Transposase and inactivated derivatives IS30 family
HOFAEECB_01188 2.5e-306 efeU_1 P Iron permease FTR1 family
HOFAEECB_01189 5.4e-108 tpd P Fe2+ transport protein
HOFAEECB_01190 1.3e-232 S Predicted membrane protein (DUF2318)
HOFAEECB_01191 3.1e-221 macB_2 V ABC transporter permease
HOFAEECB_01192 5.9e-204 Z012_06715 V FtsX-like permease family
HOFAEECB_01193 1.8e-147 macB V ABC transporter, ATP-binding protein
HOFAEECB_01194 1.3e-70 S FMN_bind
HOFAEECB_01195 3.6e-131 yydK K UTRA
HOFAEECB_01196 3.6e-67 S haloacid dehalogenase-like hydrolase
HOFAEECB_01197 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOFAEECB_01198 4.3e-49 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HOFAEECB_01199 4.4e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HOFAEECB_01200 1.4e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
HOFAEECB_01201 9.7e-29 Q phosphatase activity
HOFAEECB_01202 7e-81
HOFAEECB_01203 1.1e-239 S Putative ABC-transporter type IV
HOFAEECB_01204 2.1e-162 S Sucrose-6F-phosphate phosphohydrolase
HOFAEECB_01206 2.1e-88 E IrrE N-terminal-like domain
HOFAEECB_01207 1.6e-37 L Psort location Cytoplasmic, score 8.87
HOFAEECB_01208 3.6e-122 L Integrase core domain
HOFAEECB_01209 2.2e-09
HOFAEECB_01210 2.9e-81 K Winged helix DNA-binding domain
HOFAEECB_01211 9.2e-301 V ABC transporter, ATP-binding protein
HOFAEECB_01212 0.0 V ABC transporter transmembrane region
HOFAEECB_01213 7e-80
HOFAEECB_01214 1.2e-52 XK26_04485 P Cobalt transport protein
HOFAEECB_01216 3.5e-304 pepD E Peptidase family C69
HOFAEECB_01217 1.2e-287 S Glycosyl hydrolases related to GH101 family, GH129
HOFAEECB_01218 7.3e-94 S Glycosyl hydrolases related to GH101 family, GH129
HOFAEECB_01219 6.6e-198 XK27_01805 M Glycosyltransferase like family 2
HOFAEECB_01220 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
HOFAEECB_01222 5.3e-202 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HOFAEECB_01223 3.4e-220 amt U Ammonium Transporter Family
HOFAEECB_01224 1e-54 glnB K Nitrogen regulatory protein P-II
HOFAEECB_01225 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HOFAEECB_01226 7e-251 dinF V MatE
HOFAEECB_01227 2.2e-257 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HOFAEECB_01228 1.3e-274 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HOFAEECB_01229 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HOFAEECB_01230 3.5e-19 S granule-associated protein
HOFAEECB_01231 0.0 ubiB S ABC1 family
HOFAEECB_01232 0.0 pacS 3.6.3.54 P E1-E2 ATPase
HOFAEECB_01233 1.4e-42 csoR S Metal-sensitive transcriptional repressor
HOFAEECB_01234 1.3e-214 rmuC S RmuC family
HOFAEECB_01235 2.2e-128 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOFAEECB_01236 3.4e-155 spoU 2.1.1.185 J RNA methyltransferase TrmH family
HOFAEECB_01237 6.9e-57 V ABC transporter
HOFAEECB_01238 3.7e-55 V ABC transporter
HOFAEECB_01239 5.3e-14 V ABC transporter
HOFAEECB_01240 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOFAEECB_01241 2.4e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HOFAEECB_01242 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOFAEECB_01243 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
HOFAEECB_01244 3.3e-52 S Protein of unknown function (DUF2469)
HOFAEECB_01245 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
HOFAEECB_01246 1.6e-304 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HOFAEECB_01247 3e-234 E Aminotransferase class I and II
HOFAEECB_01248 1.5e-83 lrp_3 K helix_turn_helix ASNC type
HOFAEECB_01249 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
HOFAEECB_01250 0.0 S domain protein
HOFAEECB_01251 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HOFAEECB_01252 8.1e-293 E Bacterial extracellular solute-binding proteins, family 5 Middle
HOFAEECB_01253 9.6e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HOFAEECB_01254 1.8e-133 KT Transcriptional regulatory protein, C terminal
HOFAEECB_01255 1.4e-125
HOFAEECB_01256 3.8e-102 mntP P Probably functions as a manganese efflux pump
HOFAEECB_01258 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HOFAEECB_01259 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HOFAEECB_01260 0.0 K RNA polymerase II activating transcription factor binding
HOFAEECB_01261 3e-34
HOFAEECB_01263 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HOFAEECB_01264 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
HOFAEECB_01266 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOFAEECB_01267 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HOFAEECB_01268 4.1e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOFAEECB_01269 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HOFAEECB_01270 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HOFAEECB_01271 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HOFAEECB_01272 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HOFAEECB_01273 5.2e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HOFAEECB_01274 5.9e-146 QT PucR C-terminal helix-turn-helix domain
HOFAEECB_01275 0.0
HOFAEECB_01276 1.3e-151 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HOFAEECB_01277 4.2e-93 bioY S BioY family
HOFAEECB_01278 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HOFAEECB_01279 7.2e-308 pccB I Carboxyl transferase domain
HOFAEECB_01280 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HOFAEECB_01281 1.7e-99 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HOFAEECB_01282 1.8e-159 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HOFAEECB_01284 2.2e-134 int L Phage integrase, N-terminal SAM-like domain
HOFAEECB_01286 8.8e-82 sppA OU Serine dehydrogenase proteinase
HOFAEECB_01289 6.2e-62
HOFAEECB_01290 7.5e-63 S Bacterial PH domain
HOFAEECB_01291 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
HOFAEECB_01292 1.2e-118
HOFAEECB_01293 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HOFAEECB_01294 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HOFAEECB_01295 6.1e-115 xylR K purine nucleotide biosynthetic process
HOFAEECB_01296 2.1e-92 lemA S LemA family
HOFAEECB_01297 0.0 S Predicted membrane protein (DUF2207)
HOFAEECB_01298 9.9e-76 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HOFAEECB_01299 1e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOFAEECB_01300 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOFAEECB_01301 1.8e-96 nrdI F Probably involved in ribonucleotide reductase function
HOFAEECB_01302 2.2e-41 nrdH O Glutaredoxin
HOFAEECB_01303 1e-167 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HOFAEECB_01304 4.9e-69 L Transposase and inactivated derivatives IS30 family
HOFAEECB_01305 3.6e-290 sufB O FeS assembly protein SufB
HOFAEECB_01306 1.5e-233 sufD O FeS assembly protein SufD
HOFAEECB_01307 1.4e-144 sufC O FeS assembly ATPase SufC
HOFAEECB_01308 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HOFAEECB_01309 1.5e-100 iscU C SUF system FeS assembly protein, NifU family
HOFAEECB_01310 1.2e-108 yitW S Iron-sulfur cluster assembly protein
HOFAEECB_01311 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HOFAEECB_01312 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
HOFAEECB_01314 7.2e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HOFAEECB_01315 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HOFAEECB_01316 3.4e-197 phoH T PhoH-like protein
HOFAEECB_01317 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOFAEECB_01318 1.1e-243 corC S CBS domain
HOFAEECB_01319 5.1e-187 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOFAEECB_01320 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HOFAEECB_01321 7e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HOFAEECB_01322 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HOFAEECB_01323 3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HOFAEECB_01324 8.2e-190 S alpha beta
HOFAEECB_01325 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HOFAEECB_01326 1.8e-225 ilvE 2.6.1.42 E Amino-transferase class IV
HOFAEECB_01327 6.2e-42 S phosphoesterase or phosphohydrolase
HOFAEECB_01328 5.6e-45 3.1.4.37 T RNA ligase
HOFAEECB_01329 2.9e-134 S UPF0126 domain
HOFAEECB_01330 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
HOFAEECB_01331 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HOFAEECB_01332 5.7e-245 hemN H Involved in the biosynthesis of porphyrin-containing compound
HOFAEECB_01333 4e-13 S Membrane
HOFAEECB_01334 8.2e-293 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HOFAEECB_01335 0.0 tetP J Elongation factor G, domain IV
HOFAEECB_01336 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HOFAEECB_01337 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HOFAEECB_01338 3.6e-82
HOFAEECB_01339 1.6e-243 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
HOFAEECB_01340 8.9e-164 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
HOFAEECB_01341 1.1e-159 ybeM S Carbon-nitrogen hydrolase
HOFAEECB_01342 6.6e-116 S Sel1-like repeats.
HOFAEECB_01343 1.1e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HOFAEECB_01344 1.8e-38 L Helix-turn-helix domain
HOFAEECB_01345 2.6e-178 L Transposase
HOFAEECB_01346 3e-127 XK26_04895
HOFAEECB_01347 0.0 KL Type III restriction enzyme res subunit
HOFAEECB_01348 5.6e-159 L Eco57I restriction-modification methylase
HOFAEECB_01349 2.8e-182 3.1.21.4 V Type III restriction enzyme res subunit
HOFAEECB_01350 9.4e-56 S SIR2-like domain
HOFAEECB_01351 9.4e-251 S AAA-like domain
HOFAEECB_01352 0.0 S Protein of unknown function DUF262
HOFAEECB_01353 5e-30
HOFAEECB_01354 1.4e-92 rarD 3.4.17.13 E Rard protein
HOFAEECB_01355 5.8e-25 rarD S Rard protein
HOFAEECB_01356 2.8e-176 I alpha/beta hydrolase fold
HOFAEECB_01357 1.3e-207 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HOFAEECB_01358 4.5e-100 sixA T Phosphoglycerate mutase family
HOFAEECB_01359 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HOFAEECB_01360 9.6e-163 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
HOFAEECB_01362 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HOFAEECB_01363 6.4e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HOFAEECB_01364 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HOFAEECB_01365 6.5e-281 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HOFAEECB_01366 8.9e-181 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
HOFAEECB_01367 7.7e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HOFAEECB_01368 9.6e-180 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HOFAEECB_01369 1.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOFAEECB_01370 1.3e-24 K MerR family regulatory protein
HOFAEECB_01371 8.1e-196 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HOFAEECB_01372 1.4e-127
HOFAEECB_01373 2e-15 KLT Protein tyrosine kinase
HOFAEECB_01374 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HOFAEECB_01375 3.3e-242 vbsD V MatE
HOFAEECB_01376 9.6e-132 S Enoyl-(Acyl carrier protein) reductase
HOFAEECB_01377 7.9e-134 magIII L endonuclease III
HOFAEECB_01378 3.8e-93 laaE K Transcriptional regulator PadR-like family
HOFAEECB_01379 4e-176 S Membrane transport protein
HOFAEECB_01380 2.7e-69 4.1.1.44 S Cupin domain
HOFAEECB_01381 2e-224 hipA 2.7.11.1 S HipA N-terminal domain
HOFAEECB_01382 3.7e-41 K Helix-turn-helix
HOFAEECB_01383 2.4e-46 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
HOFAEECB_01384 5.4e-19
HOFAEECB_01385 4.6e-100 K Bacterial regulatory proteins, tetR family
HOFAEECB_01386 3.4e-20 T Domain of unknown function (DUF4234)
HOFAEECB_01387 2.2e-56 T Domain of unknown function (DUF4234)
HOFAEECB_01388 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
HOFAEECB_01389 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HOFAEECB_01390 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOFAEECB_01391 1.2e-143 4.1.1.44 S Carboxymuconolactone decarboxylase family
HOFAEECB_01392 5.7e-61 dkgB S Oxidoreductase, aldo keto reductase family protein
HOFAEECB_01394 3e-289 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HOFAEECB_01395 0.0 pafB K WYL domain
HOFAEECB_01396 7e-53
HOFAEECB_01397 0.0 helY L DEAD DEAH box helicase
HOFAEECB_01398 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HOFAEECB_01399 7.3e-143 pgp 3.1.3.18 S HAD-hyrolase-like
HOFAEECB_01402 3.6e-90 K Putative zinc ribbon domain
HOFAEECB_01403 7.2e-126 S GyrI-like small molecule binding domain
HOFAEECB_01404 3.7e-23 L DNA integration
HOFAEECB_01405 1.1e-15
HOFAEECB_01406 1.9e-62
HOFAEECB_01407 5.2e-119 K helix_turn_helix, mercury resistance
HOFAEECB_01408 9.6e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
HOFAEECB_01409 2.9e-140 S Bacterial protein of unknown function (DUF881)
HOFAEECB_01410 2.6e-31 sbp S Protein of unknown function (DUF1290)
HOFAEECB_01411 1.4e-173 S Bacterial protein of unknown function (DUF881)
HOFAEECB_01412 1.8e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOFAEECB_01413 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
HOFAEECB_01414 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HOFAEECB_01415 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
HOFAEECB_01416 4.5e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HOFAEECB_01417 6.4e-162 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HOFAEECB_01418 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HOFAEECB_01419 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
HOFAEECB_01420 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HOFAEECB_01421 5.3e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HOFAEECB_01422 5.7e-30
HOFAEECB_01423 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HOFAEECB_01424 2.7e-244
HOFAEECB_01425 1.4e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HOFAEECB_01426 3.3e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HOFAEECB_01427 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOFAEECB_01428 7.5e-39 yajC U Preprotein translocase subunit
HOFAEECB_01429 8.7e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HOFAEECB_01430 4.3e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HOFAEECB_01432 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HOFAEECB_01433 1e-131 yebC K transcriptional regulatory protein
HOFAEECB_01434 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
HOFAEECB_01435 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOFAEECB_01436 9.3e-249 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOFAEECB_01439 4.6e-238
HOFAEECB_01443 2.8e-156 S PAC2 family
HOFAEECB_01444 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HOFAEECB_01445 7.1e-160 G Fructosamine kinase
HOFAEECB_01446 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HOFAEECB_01447 5.1e-213 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HOFAEECB_01448 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
HOFAEECB_01449 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HOFAEECB_01450 1.1e-142 yoaK S Protein of unknown function (DUF1275)
HOFAEECB_01451 8.8e-254 brnQ U Component of the transport system for branched-chain amino acids
HOFAEECB_01453 2.3e-243 mepA_6 V MatE
HOFAEECB_01454 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
HOFAEECB_01455 1.3e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HOFAEECB_01456 8e-33 secG U Preprotein translocase SecG subunit
HOFAEECB_01457 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HOFAEECB_01458 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
HOFAEECB_01459 3.1e-173 whiA K May be required for sporulation
HOFAEECB_01460 1.5e-177 rapZ S Displays ATPase and GTPase activities
HOFAEECB_01461 3e-181 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
HOFAEECB_01462 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HOFAEECB_01463 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HOFAEECB_01464 4.9e-77
HOFAEECB_01466 6.2e-117 K Transcriptional regulatory protein, C terminal
HOFAEECB_01467 2.5e-240 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HOFAEECB_01468 1e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HOFAEECB_01469 2e-302 ybiT S ABC transporter
HOFAEECB_01470 8.5e-198 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HOFAEECB_01471 3.3e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HOFAEECB_01472 4.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
HOFAEECB_01473 1.4e-217 GK ROK family
HOFAEECB_01474 1.2e-177 2.7.1.2 GK ROK family
HOFAEECB_01475 5.3e-158 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
HOFAEECB_01476 1.6e-137 L Transposase and inactivated derivatives IS30 family
HOFAEECB_01477 1.2e-301 S Bifunctional DNA primase/polymerase, N-terminal
HOFAEECB_01478 3.4e-50
HOFAEECB_01479 7.6e-60
HOFAEECB_01480 2.2e-94 J tRNA 5'-leader removal
HOFAEECB_01482 8.8e-121 cyaA 4.6.1.1 S CYTH
HOFAEECB_01483 3.8e-163 trxA2 O Tetratricopeptide repeat
HOFAEECB_01484 3e-179
HOFAEECB_01485 5.8e-189
HOFAEECB_01486 9.8e-167 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HOFAEECB_01487 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HOFAEECB_01488 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HOFAEECB_01489 1e-125
HOFAEECB_01490 2.1e-131 K Bacterial regulatory proteins, tetR family
HOFAEECB_01491 7.4e-226 G Transmembrane secretion effector
HOFAEECB_01492 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOFAEECB_01493 3.6e-221 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
HOFAEECB_01494 5.1e-180 S CAAX protease self-immunity
HOFAEECB_01496 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
HOFAEECB_01497 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOFAEECB_01498 2.5e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOFAEECB_01499 1.1e-137 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HOFAEECB_01500 1.3e-251 S Calcineurin-like phosphoesterase
HOFAEECB_01503 3.6e-64 S Domain of unknown function (DUF4143)
HOFAEECB_01504 1.1e-95 S Domain of unknown function (DUF4143)
HOFAEECB_01505 6.3e-298 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOFAEECB_01507 9.9e-123 S HAD hydrolase, family IA, variant 3
HOFAEECB_01508 8.6e-201 P NMT1/THI5 like
HOFAEECB_01509 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HOFAEECB_01510 6e-142
HOFAEECB_01511 1.1e-124 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HOFAEECB_01512 1.1e-262 EGP Major facilitator Superfamily
HOFAEECB_01513 6.8e-98 S GtrA-like protein
HOFAEECB_01514 1.3e-62 S Macrophage migration inhibitory factor (MIF)
HOFAEECB_01515 6.2e-288 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HOFAEECB_01516 0.0 pepD E Peptidase family C69
HOFAEECB_01517 1.3e-107 S Phosphatidylethanolamine-binding protein
HOFAEECB_01518 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
HOFAEECB_01520 0.0 lmrA2 V ABC transporter transmembrane region
HOFAEECB_01521 0.0 lmrA1 V ABC transporter, ATP-binding protein
HOFAEECB_01522 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
HOFAEECB_01523 5.7e-191 1.1.1.65 C Aldo/keto reductase family
HOFAEECB_01524 9.1e-36 M F5/8 type C domain
HOFAEECB_01525 9.8e-52
HOFAEECB_01527 3.8e-111 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
HOFAEECB_01528 5e-116 K WHG domain
HOFAEECB_01529 2e-32 1.3.3.6, 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
HOFAEECB_01530 8.5e-266 EGP Major Facilitator Superfamily
HOFAEECB_01531 1.6e-302 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HOFAEECB_01532 6.7e-150 L HNH endonuclease
HOFAEECB_01533 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HOFAEECB_01534 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HOFAEECB_01535 1.3e-24 L Transposase
HOFAEECB_01536 4.1e-82 L Transposase
HOFAEECB_01537 2.1e-41 XAC3035 O Glutaredoxin
HOFAEECB_01538 7e-149 S Virulence factor BrkB
HOFAEECB_01539 8.4e-99 bcp 1.11.1.15 O Redoxin
HOFAEECB_01540 2.1e-36 E ABC transporter
HOFAEECB_01541 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HOFAEECB_01542 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOFAEECB_01543 0.0 V FtsX-like permease family
HOFAEECB_01544 7.5e-129 V ABC transporter
HOFAEECB_01545 7e-101 K Transcriptional regulator C-terminal region
HOFAEECB_01546 1.3e-274 aroP E aromatic amino acid transport protein AroP K03293
HOFAEECB_01547 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HOFAEECB_01549 7.5e-183 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
HOFAEECB_01550 8.2e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOFAEECB_01551 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOFAEECB_01552 1.5e-253 yhjE EGP Sugar (and other) transporter
HOFAEECB_01553 2.4e-298 scrT G Transporter major facilitator family protein
HOFAEECB_01554 5.9e-76 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HOFAEECB_01555 8.1e-196 K helix_turn _helix lactose operon repressor
HOFAEECB_01556 1.1e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOFAEECB_01557 7.4e-164 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOFAEECB_01558 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOFAEECB_01559 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HOFAEECB_01560 4.4e-252 3.5.1.104 G Polysaccharide deacetylase
HOFAEECB_01561 2.7e-28
HOFAEECB_01562 8.8e-233 ltrBE1 U Relaxase/Mobilisation nuclease domain
HOFAEECB_01563 3.1e-33 S Bacterial mobilisation protein (MobC)
HOFAEECB_01564 4.9e-82 S GyrI-like small molecule binding domain
HOFAEECB_01565 1.3e-40 S Polyketide cyclase / dehydrase and lipid transport
HOFAEECB_01566 6.1e-70 K FR47-like protein
HOFAEECB_01567 2.8e-80 S Nucleotidyltransferase domain
HOFAEECB_01568 2.3e-195
HOFAEECB_01569 5e-84 S Protein of unknown function DUF262
HOFAEECB_01570 8.5e-63 S Protein of unknown function DUF262
HOFAEECB_01572 8.4e-168 htpX O Belongs to the peptidase M48B family
HOFAEECB_01573 1.5e-272 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HOFAEECB_01574 0.0 cadA P E1-E2 ATPase
HOFAEECB_01575 3.3e-232 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HOFAEECB_01576 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HOFAEECB_01578 2.6e-85 yjcF Q Acetyltransferase (GNAT) domain
HOFAEECB_01579 3.8e-156 I Serine aminopeptidase, S33
HOFAEECB_01580 9.3e-53 ybjQ S Putative heavy-metal-binding
HOFAEECB_01581 8.8e-42 D DivIVA domain protein
HOFAEECB_01582 9.3e-89 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HOFAEECB_01583 0.0 KL Domain of unknown function (DUF3427)
HOFAEECB_01585 1.6e-196 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOFAEECB_01587 2.6e-103
HOFAEECB_01588 6e-169 yicL EG EamA-like transporter family
HOFAEECB_01589 7.1e-208 pldB 3.1.1.5 I Serine aminopeptidase, S33
HOFAEECB_01590 0.0 pip S YhgE Pip domain protein
HOFAEECB_01591 0.0 pip S YhgE Pip domain protein
HOFAEECB_01592 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HOFAEECB_01593 1e-130 fhaA T Protein of unknown function (DUF2662)
HOFAEECB_01594 1.3e-93 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HOFAEECB_01595 4.7e-259 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HOFAEECB_01596 9.8e-264 rodA D Belongs to the SEDS family
HOFAEECB_01597 2.8e-263 pbpA M penicillin-binding protein
HOFAEECB_01598 2e-183 T Protein tyrosine kinase
HOFAEECB_01599 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
HOFAEECB_01600 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HOFAEECB_01601 2.6e-233 srtA 3.4.22.70 M Sortase family
HOFAEECB_01602 7.9e-143 S Bacterial protein of unknown function (DUF881)
HOFAEECB_01603 2.6e-71 crgA D Involved in cell division
HOFAEECB_01604 2.8e-257 L ribosomal rna small subunit methyltransferase
HOFAEECB_01605 2e-91 L HTH-like domain
HOFAEECB_01606 8.4e-145 gluP 3.4.21.105 S Rhomboid family
HOFAEECB_01607 3.4e-35
HOFAEECB_01608 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HOFAEECB_01609 2e-73 I Sterol carrier protein
HOFAEECB_01610 3.4e-36 V ATPases associated with a variety of cellular activities
HOFAEECB_01611 1.6e-44 L Transposase
HOFAEECB_01612 2.3e-45 L DNA-dependent DNA replication
HOFAEECB_01613 1.1e-42 tnp7109-21 L Integrase core domain
HOFAEECB_01614 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
HOFAEECB_01615 4.5e-12
HOFAEECB_01616 5.2e-57 yccF S Inner membrane component domain
HOFAEECB_01617 4.8e-257 S Domain of unknown function (DUF4143)
HOFAEECB_01618 1.7e-160 tnp7109-21 L Integrase core domain
HOFAEECB_01619 4.8e-307 3.6.4.12 K Putative DNA-binding domain
HOFAEECB_01620 2.2e-95
HOFAEECB_01621 2.4e-09 G Acyltransferase family
HOFAEECB_01623 1.7e-113 M Glycosyltransferase like family 2
HOFAEECB_01624 3.8e-78 rfbN GT2 M Glycosyl transferase family 2
HOFAEECB_01625 1.1e-111 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
HOFAEECB_01626 9.6e-92 M Polysaccharide pyruvyl transferase
HOFAEECB_01627 2.9e-107 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HOFAEECB_01628 2.9e-76 rgpC GM Transport permease protein
HOFAEECB_01629 2.8e-160 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HOFAEECB_01630 2.8e-255 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HOFAEECB_01631 6.9e-200 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOFAEECB_01632 1.1e-114 L Transposase, Mutator family
HOFAEECB_01633 5.7e-37
HOFAEECB_01634 5.9e-238 5.4.99.9 H Flavin containing amine oxidoreductase
HOFAEECB_01635 1.1e-216 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HOFAEECB_01636 5.5e-30 I transferase activity, transferring acyl groups other than amino-acyl groups
HOFAEECB_01637 1e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOFAEECB_01638 2e-61 T protein histidine kinase activity
HOFAEECB_01639 1.3e-88 K LytTr DNA-binding domain
HOFAEECB_01640 6.2e-45 S Protein of unknown function (DUF3073)
HOFAEECB_01641 6.5e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HOFAEECB_01642 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HOFAEECB_01643 9.9e-172 L Transposase and inactivated derivatives IS30 family
HOFAEECB_01644 6.5e-180 S Amidohydrolase family
HOFAEECB_01645 0.0 yjjP S Threonine/Serine exporter, ThrE
HOFAEECB_01646 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HOFAEECB_01647 7.3e-239 yhjX EGP Major facilitator Superfamily
HOFAEECB_01648 0.0 trxB1 1.8.1.9 C Thioredoxin domain
HOFAEECB_01649 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HOFAEECB_01650 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HOFAEECB_01651 2.4e-52 K helix_turn _helix lactose operon repressor
HOFAEECB_01652 1.2e-241 ytfL P Transporter associated domain
HOFAEECB_01653 2.6e-189 yddG EG EamA-like transporter family
HOFAEECB_01654 1.9e-83 dps P Belongs to the Dps family
HOFAEECB_01655 6.7e-136 S Protein of unknown function DUF45
HOFAEECB_01656 3.6e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HOFAEECB_01657 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HOFAEECB_01658 7.3e-77 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HOFAEECB_01659 3.7e-188 K helix_turn _helix lactose operon repressor
HOFAEECB_01660 0.0 G Glycosyl hydrolase family 20, domain 2
HOFAEECB_01663 0.0 3.2.1.55 GH51 G arabinose metabolic process
HOFAEECB_01664 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HOFAEECB_01665 7.6e-121 gntR K FCD
HOFAEECB_01666 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HOFAEECB_01667 1.8e-24 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HOFAEECB_01670 1.4e-14 K Helix-turn-helix domain
HOFAEECB_01671 3.4e-18 S Domain of unknown function (DUF4160)
HOFAEECB_01672 9.6e-42 S Protein of unknown function (DUF2442)
HOFAEECB_01673 6.7e-09 K helix_turn _helix lactose operon repressor
HOFAEECB_01674 1.2e-227 I Serine aminopeptidase, S33
HOFAEECB_01675 5.1e-186 K Periplasmic binding protein domain
HOFAEECB_01676 3.5e-187 G Glycosyl hydrolases family 43
HOFAEECB_01677 4.5e-15 abfA1 3.2.1.55 GH51 G arabinose metabolic process
HOFAEECB_01678 6.1e-73 S Transmembrane domain of unknown function (DUF3566)
HOFAEECB_01679 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOFAEECB_01680 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOFAEECB_01681 9.2e-93 S Protein of unknown function (DUF721)
HOFAEECB_01682 2.8e-238 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOFAEECB_01683 6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HOFAEECB_01684 1.2e-299 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HOFAEECB_01685 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HOFAEECB_01686 1.9e-170 yidC U Membrane protein insertase, YidC Oxa1 family
HOFAEECB_01687 6.5e-93 jag S Putative single-stranded nucleic acids-binding domain
HOFAEECB_01688 2.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HOFAEECB_01689 3.8e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HOFAEECB_01690 1.2e-244 parB K Belongs to the ParB family
HOFAEECB_01691 1.5e-203 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HOFAEECB_01692 0.0 murJ KLT MviN-like protein
HOFAEECB_01693 0.0 M Conserved repeat domain
HOFAEECB_01694 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HOFAEECB_01695 9.5e-280 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HOFAEECB_01696 6.7e-113 S LytR cell envelope-related transcriptional attenuator
HOFAEECB_01697 3.5e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HOFAEECB_01698 6.3e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HOFAEECB_01699 1.4e-212 S G5
HOFAEECB_01701 8.4e-151 O Thioredoxin
HOFAEECB_01702 0.0 KLT Protein tyrosine kinase
HOFAEECB_01703 6.4e-173 K Psort location Cytoplasmic, score
HOFAEECB_01704 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
HOFAEECB_01705 8e-102 L Helix-turn-helix domain
HOFAEECB_01706 0.0 S LPXTG-motif cell wall anchor domain protein
HOFAEECB_01707 2e-238 M LPXTG-motif cell wall anchor domain protein
HOFAEECB_01708 4.1e-181 3.4.22.70 M Sortase family
HOFAEECB_01709 1.6e-149
HOFAEECB_01710 7.5e-269 KLT Domain of unknown function (DUF4032)
HOFAEECB_01711 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOFAEECB_01713 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HOFAEECB_01714 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HOFAEECB_01715 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HOFAEECB_01716 0.0 yjcE P Sodium/hydrogen exchanger family
HOFAEECB_01717 5.1e-144 ypfH S Phospholipase/Carboxylesterase
HOFAEECB_01718 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HOFAEECB_01719 2.2e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HOFAEECB_01720 3e-144 cobB2 K Sir2 family
HOFAEECB_01721 1.7e-108
HOFAEECB_01722 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HOFAEECB_01723 7.7e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HOFAEECB_01724 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HOFAEECB_01725 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HOFAEECB_01726 1.2e-31 J Acetyltransferase (GNAT) domain
HOFAEECB_01727 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HOFAEECB_01728 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
HOFAEECB_01729 2e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOFAEECB_01730 1.1e-247 dgt 3.1.5.1 F Phosphohydrolase-associated domain
HOFAEECB_01731 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HOFAEECB_01732 1.3e-159 K Helix-turn-helix domain, rpiR family
HOFAEECB_01733 3e-226 K Putative ATP-dependent DNA helicase recG C-terminal
HOFAEECB_01734 1.4e-44 S Memo-like protein
HOFAEECB_01736 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOFAEECB_01737 8.5e-179 adh3 C Zinc-binding dehydrogenase
HOFAEECB_01738 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HOFAEECB_01739 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HOFAEECB_01740 1.5e-73 zur P Belongs to the Fur family
HOFAEECB_01741 2.9e-44
HOFAEECB_01742 1.2e-51 S TIGRFAM TIGR03943 family protein
HOFAEECB_01743 1.2e-65 S TIGRFAM TIGR03943 family protein
HOFAEECB_01744 6.9e-201 ycgR S Predicted permease
HOFAEECB_01745 2.3e-23 J Ribosomal L32p protein family
HOFAEECB_01746 8.2e-15 rpmJ J Ribosomal protein L36
HOFAEECB_01747 2.2e-41 rpmE2 J Ribosomal protein L31
HOFAEECB_01748 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOFAEECB_01749 8.8e-47 rpmB J Ribosomal L28 family
HOFAEECB_01750 4.3e-138 S cobalamin synthesis protein
HOFAEECB_01751 4.6e-163 P Zinc-uptake complex component A periplasmic
HOFAEECB_01753 0.0 lysX S Uncharacterised conserved protein (DUF2156)
HOFAEECB_01754 1.3e-246 S Putative esterase
HOFAEECB_01755 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HOFAEECB_01756 5e-240 purD 6.3.4.13 F Belongs to the GARS family
HOFAEECB_01757 2e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HOFAEECB_01758 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOFAEECB_01759 1.4e-303 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
HOFAEECB_01760 2e-32
HOFAEECB_01761 1.8e-68 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOFAEECB_01762 8.9e-33 K DNA-binding transcription factor activity
HOFAEECB_01763 6.8e-104 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
HOFAEECB_01764 9e-97 S Protein of unknown function (DUF4230)
HOFAEECB_01765 2.1e-107
HOFAEECB_01766 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HOFAEECB_01767 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HOFAEECB_01768 6.4e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HOFAEECB_01770 0.0 M Parallel beta-helix repeats
HOFAEECB_01771 5.4e-228 M Glycosyl transferase 4-like domain
HOFAEECB_01772 1.3e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
HOFAEECB_01774 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HOFAEECB_01775 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HOFAEECB_01776 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOFAEECB_01777 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOFAEECB_01778 0.0 S Esterase-like activity of phytase
HOFAEECB_01779 1.5e-190 EGP Transmembrane secretion effector
HOFAEECB_01781 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOFAEECB_01782 1.6e-88 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOFAEECB_01783 1.3e-237 carA 6.3.5.5 F Belongs to the CarA family
HOFAEECB_01784 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HOFAEECB_01785 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HOFAEECB_01786 0.0 S Protein of unknown function DUF262
HOFAEECB_01787 1.1e-116 K helix_turn_helix, Lux Regulon
HOFAEECB_01788 3.2e-267 T Histidine kinase
HOFAEECB_01789 1e-97 S Domain of unknown function (DUF5067)
HOFAEECB_01790 6.6e-132 ybhL S Belongs to the BI1 family
HOFAEECB_01791 2e-169 ydeD EG EamA-like transporter family
HOFAEECB_01792 3.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HOFAEECB_01793 8.2e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HOFAEECB_01794 2e-184 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HOFAEECB_01795 2e-137 fic D Fic/DOC family
HOFAEECB_01796 0.0 ftsK D FtsK SpoIIIE family protein
HOFAEECB_01797 9.2e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOFAEECB_01798 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
HOFAEECB_01799 7.3e-81 K Helix-turn-helix XRE-family like proteins
HOFAEECB_01800 1.4e-39 S Protein of unknown function (DUF3046)
HOFAEECB_01801 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOFAEECB_01802 9.3e-74 recX S Modulates RecA activity
HOFAEECB_01804 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOFAEECB_01805 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HOFAEECB_01806 4.3e-65 L single-stranded DNA binding
HOFAEECB_01807 1.5e-55
HOFAEECB_01808 5.4e-60
HOFAEECB_01809 1.8e-36
HOFAEECB_01810 9e-17
HOFAEECB_01811 1.1e-50
HOFAEECB_01812 2.9e-26
HOFAEECB_01814 4e-50 K Helix-turn-helix XRE-family like proteins
HOFAEECB_01815 4.8e-14
HOFAEECB_01816 1.4e-191 L Phage integrase family
HOFAEECB_01818 6.8e-13 V HNH nucleases
HOFAEECB_01819 7.3e-18
HOFAEECB_01821 7.5e-15
HOFAEECB_01822 2.5e-219 S Terminase
HOFAEECB_01823 1.7e-40 S Phage portal protein, SPP1 Gp6-like
HOFAEECB_01824 2.7e-119 S Phage portal protein, SPP1 Gp6-like
HOFAEECB_01825 6.3e-60
HOFAEECB_01826 1.4e-21
HOFAEECB_01827 1e-133 S Phage capsid family
HOFAEECB_01828 3.1e-29
HOFAEECB_01829 5e-51 S Phage protein Gp19/Gp15/Gp42
HOFAEECB_01830 2.4e-32
HOFAEECB_01831 1.1e-76 eae N domain, Protein
HOFAEECB_01832 1.6e-28
HOFAEECB_01833 1.6e-39
HOFAEECB_01834 1.6e-246 S phage tail tape measure protein
HOFAEECB_01835 2.5e-102
HOFAEECB_01836 5.7e-223 S Phage minor structural protein
HOFAEECB_01837 4e-112
HOFAEECB_01838 5.5e-37
HOFAEECB_01840 1.8e-101 M Glycosyl hydrolases family 25
HOFAEECB_01841 2e-21
HOFAEECB_01842 1.8e-227 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HOFAEECB_01843 1.3e-228 S MvaI/BcnI restriction endonuclease family
HOFAEECB_01844 1.7e-70
HOFAEECB_01845 4.2e-149 S Uncharacterised protein conserved in bacteria (DUF2326)
HOFAEECB_01846 3.8e-42 2.7.7.7 L Transposase, Mutator family
HOFAEECB_01847 3.4e-240 L PFAM Integrase catalytic
HOFAEECB_01848 2e-133 L IstB-like ATP binding protein
HOFAEECB_01849 4.9e-92 2.7.7.7 L Transposase, Mutator family
HOFAEECB_01851 5.3e-184 K Bacterial regulatory proteins, lacI family
HOFAEECB_01852 3.5e-17 4.2.1.68 M carboxylic acid catabolic process
HOFAEECB_01853 3.5e-19 4.2.1.68 M Enolase C-terminal domain-like
HOFAEECB_01854 1.1e-152 IQ KR domain
HOFAEECB_01856 1.1e-52 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)