ORF_ID e_value Gene_name EC_number CAZy COGs Description
KEFEFEAG_00002 1.8e-161 S reductase
KEFEFEAG_00003 3.4e-171 L Integrase core domain
KEFEFEAG_00004 1.9e-46 L Transposase
KEFEFEAG_00005 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KEFEFEAG_00006 1.6e-235 L Integrase core domain
KEFEFEAG_00007 1.9e-83 L helicase activity
KEFEFEAG_00009 7e-55 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KEFEFEAG_00010 2.7e-19
KEFEFEAG_00011 2.6e-149 purR 2.4.2.7 F pur operon repressor
KEFEFEAG_00012 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KEFEFEAG_00013 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KEFEFEAG_00014 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KEFEFEAG_00015 5.5e-45 yitW S Pfam:DUF59
KEFEFEAG_00016 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KEFEFEAG_00017 7.1e-101 ydaM M Glycosyl transferase family group 2
KEFEFEAG_00018 3.4e-224 G Glycosyl hydrolases family 8
KEFEFEAG_00019 1.3e-122 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KEFEFEAG_00020 4.4e-184 S Phosphotransferase system, EIIC
KEFEFEAG_00021 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KEFEFEAG_00022 0.0 lacS G Transporter
KEFEFEAG_00023 1.6e-170 XK27_00915 C Luciferase-like monooxygenase
KEFEFEAG_00024 2.6e-74 ogt 2.1.1.63 L Methyltransferase
KEFEFEAG_00025 1.6e-42 pnb C nitroreductase
KEFEFEAG_00026 1.8e-176 comEC S Competence protein ComEC
KEFEFEAG_00027 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
KEFEFEAG_00028 2.5e-68 comEA L Competence protein ComEA
KEFEFEAG_00029 1.6e-262 L Transposase
KEFEFEAG_00030 1.4e-81 F Belongs to the NrdI family
KEFEFEAG_00031 6.6e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KEFEFEAG_00032 4.9e-69 rnhA 3.1.26.4 L Ribonuclease HI
KEFEFEAG_00033 1.5e-65 esbA S Family of unknown function (DUF5322)
KEFEFEAG_00034 2.2e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KEFEFEAG_00035 4e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KEFEFEAG_00036 2.1e-207 carA 6.3.5.5 F Belongs to the CarA family
KEFEFEAG_00037 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KEFEFEAG_00038 0.0 FbpA K Fibronectin-binding protein
KEFEFEAG_00039 6.4e-162 degV S EDD domain protein, DegV family
KEFEFEAG_00040 1.7e-93
KEFEFEAG_00041 4.3e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KEFEFEAG_00042 4.9e-159 gspA M family 8
KEFEFEAG_00043 4.4e-160 S Alpha beta hydrolase
KEFEFEAG_00044 5.3e-95 K Acetyltransferase (GNAT) domain
KEFEFEAG_00045 8.7e-243 XK27_08635 S UPF0210 protein
KEFEFEAG_00046 2.1e-39 gcvR T Belongs to the UPF0237 family
KEFEFEAG_00047 2.9e-170 1.1.1.346 C Aldo keto reductase
KEFEFEAG_00048 5.5e-161 K LysR substrate binding domain protein
KEFEFEAG_00049 7.7e-85 C Flavodoxin
KEFEFEAG_00050 1e-80 yphH S Cupin domain
KEFEFEAG_00051 1e-73 yeaL S UPF0756 membrane protein
KEFEFEAG_00052 1.9e-237 EGP Major facilitator Superfamily
KEFEFEAG_00053 1.9e-74 copY K Copper transport repressor CopY TcrY
KEFEFEAG_00054 8.5e-246 yhdP S Transporter associated domain
KEFEFEAG_00055 0.0 ubiB S ABC1 family
KEFEFEAG_00056 1.8e-142 S DUF218 domain
KEFEFEAG_00057 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KEFEFEAG_00058 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEFEFEAG_00059 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KEFEFEAG_00060 0.0 uvrA3 L excinuclease ABC, A subunit
KEFEFEAG_00061 5.1e-122 S SNARE associated Golgi protein
KEFEFEAG_00062 7.4e-228 N Uncharacterized conserved protein (DUF2075)
KEFEFEAG_00063 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KEFEFEAG_00065 1e-254 yifK E Amino acid permease
KEFEFEAG_00066 5.5e-158 endA V DNA/RNA non-specific endonuclease
KEFEFEAG_00067 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KEFEFEAG_00068 2.1e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KEFEFEAG_00069 2.1e-126
KEFEFEAG_00070 5.5e-280 O Arylsulfotransferase (ASST)
KEFEFEAG_00071 7.6e-163 akr5f 1.1.1.346 S reductase
KEFEFEAG_00072 4.3e-40 K Transcriptional regulator
KEFEFEAG_00073 4.3e-59 K Transcriptional regulator
KEFEFEAG_00074 7e-92
KEFEFEAG_00075 9.7e-101 M domain protein
KEFEFEAG_00076 2.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KEFEFEAG_00077 4.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KEFEFEAG_00080 9.6e-200 xerS L Belongs to the 'phage' integrase family
KEFEFEAG_00082 6e-39 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KEFEFEAG_00101 1.1e-72
KEFEFEAG_00102 5.7e-172
KEFEFEAG_00111 8.2e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
KEFEFEAG_00112 0.0 rafA 3.2.1.22 G alpha-galactosidase
KEFEFEAG_00113 4.2e-189 galR K Periplasmic binding protein-like domain
KEFEFEAG_00114 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KEFEFEAG_00115 9.3e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KEFEFEAG_00116 2.6e-124 lrgB M LrgB-like family
KEFEFEAG_00117 1.9e-66 lrgA S LrgA family
KEFEFEAG_00118 2.4e-130 lytT K response regulator receiver
KEFEFEAG_00119 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
KEFEFEAG_00120 4e-148 f42a O Band 7 protein
KEFEFEAG_00121 1e-259 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KEFEFEAG_00122 3.8e-156 yitU 3.1.3.104 S hydrolase
KEFEFEAG_00123 9.2e-39 S Cytochrome B5
KEFEFEAG_00124 9.8e-115 nreC K PFAM regulatory protein LuxR
KEFEFEAG_00125 6.1e-160 hipB K Helix-turn-helix
KEFEFEAG_00126 2.8e-57 yitW S Iron-sulfur cluster assembly protein
KEFEFEAG_00127 1.6e-271 sufB O assembly protein SufB
KEFEFEAG_00128 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
KEFEFEAG_00129 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KEFEFEAG_00130 7.3e-239 sufD O FeS assembly protein SufD
KEFEFEAG_00131 6.5e-145 sufC O FeS assembly ATPase SufC
KEFEFEAG_00132 4.2e-32 feoA P FeoA domain
KEFEFEAG_00133 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KEFEFEAG_00134 5.5e-19
KEFEFEAG_00135 2e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KEFEFEAG_00136 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KEFEFEAG_00137 3.5e-64 ydiI Q Thioesterase superfamily
KEFEFEAG_00138 5.4e-109 yvrI K sigma factor activity
KEFEFEAG_00139 5e-202 G Transporter, major facilitator family protein
KEFEFEAG_00140 0.0 S Bacterial membrane protein YfhO
KEFEFEAG_00141 4.7e-102 T Ion transport 2 domain protein
KEFEFEAG_00142 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KEFEFEAG_00143 5.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KEFEFEAG_00144 1.2e-95 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KEFEFEAG_00145 2.5e-184 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KEFEFEAG_00146 3.7e-179 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KEFEFEAG_00147 6.6e-262 S Putative peptidoglycan binding domain
KEFEFEAG_00148 2.9e-187 D Alpha beta
KEFEFEAG_00149 1.9e-51 ypaA S Protein of unknown function (DUF1304)
KEFEFEAG_00150 9.3e-178 xerC L Belongs to the 'phage' integrase family
KEFEFEAG_00151 1.6e-23 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
KEFEFEAG_00152 2.2e-229 L transposase, IS605 OrfB family
KEFEFEAG_00153 6.2e-260 S Uncharacterised protein family (UPF0236)
KEFEFEAG_00154 1.3e-46
KEFEFEAG_00155 3.2e-96 S PFAM Archaeal ATPase
KEFEFEAG_00156 1.4e-78 K AsnC family
KEFEFEAG_00157 1.6e-79 uspA T universal stress protein
KEFEFEAG_00158 8.1e-238 L Transposase
KEFEFEAG_00159 3.7e-56 ltrA S Bacterial low temperature requirement A protein (LtrA)
KEFEFEAG_00160 2.3e-44 ltrA S Bacterial low temperature requirement A protein (LtrA)
KEFEFEAG_00161 7.9e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
KEFEFEAG_00162 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KEFEFEAG_00163 1.4e-47 gcvH E glycine cleavage
KEFEFEAG_00164 1.1e-220 rodA D Belongs to the SEDS family
KEFEFEAG_00165 1e-31 S Protein of unknown function (DUF2969)
KEFEFEAG_00166 1.9e-178 mbl D Cell shape determining protein MreB Mrl
KEFEFEAG_00167 3.2e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KEFEFEAG_00168 1.3e-33 ywzB S Protein of unknown function (DUF1146)
KEFEFEAG_00169 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KEFEFEAG_00170 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KEFEFEAG_00171 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KEFEFEAG_00172 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KEFEFEAG_00173 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KEFEFEAG_00174 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KEFEFEAG_00175 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KEFEFEAG_00176 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
KEFEFEAG_00177 5e-232 pyrP F Permease
KEFEFEAG_00178 6.3e-129 yibF S overlaps another CDS with the same product name
KEFEFEAG_00179 9.9e-192 yibE S overlaps another CDS with the same product name
KEFEFEAG_00180 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KEFEFEAG_00181 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KEFEFEAG_00182 7.8e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KEFEFEAG_00183 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KEFEFEAG_00184 5.7e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KEFEFEAG_00185 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KEFEFEAG_00186 6e-108 tdk 2.7.1.21 F thymidine kinase
KEFEFEAG_00187 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
KEFEFEAG_00188 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KEFEFEAG_00189 2.7e-223 arcD U Amino acid permease
KEFEFEAG_00190 4.9e-260 E Arginine ornithine antiporter
KEFEFEAG_00191 2.7e-79 argR K Regulates arginine biosynthesis genes
KEFEFEAG_00192 4.1e-239 arcA 3.5.3.6 E Arginine
KEFEFEAG_00193 3.9e-187 ampC V Beta-lactamase
KEFEFEAG_00194 2.3e-30 yviA S Protein of unknown function (DUF421)
KEFEFEAG_00195 3.1e-72 S Protein of unknown function (DUF3290)
KEFEFEAG_00196 6.2e-41 ybaN S Protein of unknown function (DUF454)
KEFEFEAG_00197 2.1e-31
KEFEFEAG_00198 2.7e-24
KEFEFEAG_00199 1.3e-112 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KEFEFEAG_00200 4.4e-34 hrtB V ABC transporter permease
KEFEFEAG_00201 6.1e-174 L PFAM Integrase catalytic region
KEFEFEAG_00202 3e-149 L Transposase and inactivated derivatives IS30 family
KEFEFEAG_00203 6.8e-139 comEC S Competence protein ComEC
KEFEFEAG_00204 5.5e-80 L transposase and inactivated derivatives, IS30 family
KEFEFEAG_00205 1.1e-83 L PFAM transposase IS200-family protein
KEFEFEAG_00207 1.5e-72 M PFAM NLP P60 protein
KEFEFEAG_00208 2.2e-182 ABC-SBP S ABC transporter
KEFEFEAG_00209 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KEFEFEAG_00210 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
KEFEFEAG_00211 1.2e-92 P Cadmium resistance transporter
KEFEFEAG_00212 6.8e-56 K Transcriptional regulator, ArsR family
KEFEFEAG_00213 5.5e-55 M Leucine-rich repeat (LRR) protein
KEFEFEAG_00214 1.6e-236 mepA V MATE efflux family protein
KEFEFEAG_00215 2.1e-54 trxA O Belongs to the thioredoxin family
KEFEFEAG_00216 5.1e-131 terC P membrane
KEFEFEAG_00217 4.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KEFEFEAG_00218 2.2e-168 corA P CorA-like Mg2+ transporter protein
KEFEFEAG_00219 1.6e-305 L Transposase
KEFEFEAG_00220 1.4e-283 pipD E Dipeptidase
KEFEFEAG_00221 1.6e-241 pbuX F xanthine permease
KEFEFEAG_00222 1.8e-251 nhaC C Na H antiporter NhaC
KEFEFEAG_00223 4e-240 S C4-dicarboxylate anaerobic carrier
KEFEFEAG_00224 1.1e-27 S C4-dicarboxylate anaerobic carrier
KEFEFEAG_00225 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
KEFEFEAG_00226 1.3e-41
KEFEFEAG_00227 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KEFEFEAG_00228 3.8e-207 gldA 1.1.1.6 C dehydrogenase
KEFEFEAG_00229 5.5e-126 S Alpha beta hydrolase
KEFEFEAG_00230 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KEFEFEAG_00231 2.5e-101
KEFEFEAG_00233 1.4e-124 yciB M ErfK YbiS YcfS YnhG
KEFEFEAG_00235 3.8e-76 lmrB EGP Major facilitator Superfamily
KEFEFEAG_00236 9.8e-86 yunF F Protein of unknown function DUF72
KEFEFEAG_00237 1.6e-21 K helix_turn_helix, mercury resistance
KEFEFEAG_00238 8.1e-230
KEFEFEAG_00239 7.2e-234 EGP Sugar (and other) transporter
KEFEFEAG_00240 6e-255 yfnA E Amino Acid
KEFEFEAG_00241 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KEFEFEAG_00242 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
KEFEFEAG_00243 1.5e-82 zur P Belongs to the Fur family
KEFEFEAG_00244 4e-17 3.2.1.14 GH18
KEFEFEAG_00245 8.3e-151
KEFEFEAG_00246 5.8e-39 pspC KT PspC domain protein
KEFEFEAG_00247 1.6e-94 K Transcriptional regulator (TetR family)
KEFEFEAG_00248 5.3e-221 V domain protein
KEFEFEAG_00249 7.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEFEFEAG_00251 6.6e-35 S Transglycosylase associated protein
KEFEFEAG_00252 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KEFEFEAG_00253 4.2e-126 3.1.3.73 G phosphoglycerate mutase
KEFEFEAG_00254 1.2e-115 dedA S SNARE associated Golgi protein
KEFEFEAG_00255 0.0 helD 3.6.4.12 L DNA helicase
KEFEFEAG_00256 2.9e-36 nox C NADH oxidase
KEFEFEAG_00257 4.7e-157 EG EamA-like transporter family
KEFEFEAG_00258 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KEFEFEAG_00259 3.1e-175 coaA 2.7.1.33 F Pantothenic acid kinase
KEFEFEAG_00260 1.5e-225 S cog cog1373
KEFEFEAG_00262 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KEFEFEAG_00263 4.9e-224 oxlT P Major Facilitator Superfamily
KEFEFEAG_00264 1.1e-158 spoU 2.1.1.185 J Methyltransferase
KEFEFEAG_00265 2.8e-24
KEFEFEAG_00267 1.3e-235 pbuG S permease
KEFEFEAG_00268 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KEFEFEAG_00269 4.5e-252 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KEFEFEAG_00270 3.8e-215 iscS2 2.8.1.7 E Aminotransferase class V
KEFEFEAG_00271 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KEFEFEAG_00272 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KEFEFEAG_00273 3.6e-271 cydA 1.10.3.14 C ubiquinol oxidase
KEFEFEAG_00274 4.1e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KEFEFEAG_00275 6.1e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KEFEFEAG_00276 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KEFEFEAG_00277 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
KEFEFEAG_00278 9.1e-245 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KEFEFEAG_00279 1.2e-122 radC L DNA repair protein
KEFEFEAG_00280 1.7e-179 mreB D cell shape determining protein MreB
KEFEFEAG_00281 5e-151 mreC M Involved in formation and maintenance of cell shape
KEFEFEAG_00282 8.7e-93 mreD M rod shape-determining protein MreD
KEFEFEAG_00283 3.2e-102 glnP P ABC transporter permease
KEFEFEAG_00284 4e-116 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KEFEFEAG_00285 2.6e-160 aatB ET ABC transporter substrate-binding protein
KEFEFEAG_00286 1.3e-229 ymfF S Peptidase M16 inactive domain protein
KEFEFEAG_00287 2.7e-249 ymfH S Peptidase M16
KEFEFEAG_00288 3.7e-148 ymfM S Helix-turn-helix domain
KEFEFEAG_00289 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KEFEFEAG_00290 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
KEFEFEAG_00291 3.7e-54
KEFEFEAG_00292 9.9e-206 yttB EGP Major facilitator Superfamily
KEFEFEAG_00293 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KEFEFEAG_00294 2e-74 rplI J Binds to the 23S rRNA
KEFEFEAG_00295 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KEFEFEAG_00296 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KEFEFEAG_00297 1.4e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KEFEFEAG_00298 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KEFEFEAG_00299 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KEFEFEAG_00300 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KEFEFEAG_00301 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KEFEFEAG_00302 1.7e-34 yaaA S S4 domain protein YaaA
KEFEFEAG_00303 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
KEFEFEAG_00304 1.6e-81 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
KEFEFEAG_00305 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KEFEFEAG_00306 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KEFEFEAG_00307 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KEFEFEAG_00308 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KEFEFEAG_00309 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KEFEFEAG_00310 3.3e-130 jag S R3H domain protein
KEFEFEAG_00311 8.7e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KEFEFEAG_00312 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KEFEFEAG_00313 0.0 asnB 6.3.5.4 E Asparagine synthase
KEFEFEAG_00314 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KEFEFEAG_00315 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
KEFEFEAG_00316 2.5e-142 lmrB EGP Major facilitator Superfamily
KEFEFEAG_00317 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KEFEFEAG_00318 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KEFEFEAG_00319 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
KEFEFEAG_00320 2.6e-80 lytE M LysM domain protein
KEFEFEAG_00321 0.0 oppD EP Psort location Cytoplasmic, score
KEFEFEAG_00322 2.3e-93 lytE M LysM domain protein
KEFEFEAG_00323 6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
KEFEFEAG_00324 6.9e-167 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KEFEFEAG_00325 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
KEFEFEAG_00326 3.1e-153 yeaE S Aldo keto
KEFEFEAG_00327 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
KEFEFEAG_00328 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
KEFEFEAG_00329 2.9e-78 S Psort location Cytoplasmic, score
KEFEFEAG_00330 7.7e-86 S Short repeat of unknown function (DUF308)
KEFEFEAG_00331 1e-23
KEFEFEAG_00332 2.8e-102 V VanZ like family
KEFEFEAG_00333 4.8e-233 cycA E Amino acid permease
KEFEFEAG_00334 4.3e-85 perR P Belongs to the Fur family
KEFEFEAG_00335 1.5e-253 EGP Major facilitator Superfamily
KEFEFEAG_00336 9.6e-92 tag 3.2.2.20 L glycosylase
KEFEFEAG_00337 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KEFEFEAG_00338 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEFEFEAG_00339 4.9e-41
KEFEFEAG_00340 1.6e-302 ytgP S Polysaccharide biosynthesis protein
KEFEFEAG_00341 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KEFEFEAG_00342 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KEFEFEAG_00343 9.7e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KEFEFEAG_00344 1.9e-22 K helix_turn_helix, arabinose operon control protein
KEFEFEAG_00345 9.2e-185 thrC 4.2.3.1 E Threonine synthase
KEFEFEAG_00346 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KEFEFEAG_00347 1.4e-100 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KEFEFEAG_00348 5.6e-62 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KEFEFEAG_00349 3.6e-185 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KEFEFEAG_00350 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KEFEFEAG_00351 8.1e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KEFEFEAG_00352 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KEFEFEAG_00353 5.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KEFEFEAG_00354 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEFEFEAG_00355 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEFEFEAG_00356 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KEFEFEAG_00357 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KEFEFEAG_00358 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KEFEFEAG_00359 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KEFEFEAG_00360 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KEFEFEAG_00361 7.6e-241 purD 6.3.4.13 F Belongs to the GARS family
KEFEFEAG_00362 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KEFEFEAG_00363 9.7e-173
KEFEFEAG_00364 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KEFEFEAG_00365 1.8e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KEFEFEAG_00366 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KEFEFEAG_00367 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KEFEFEAG_00368 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KEFEFEAG_00369 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KEFEFEAG_00370 3.8e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KEFEFEAG_00371 9.8e-67 yabR J RNA binding
KEFEFEAG_00372 3.3e-56 divIC D Septum formation initiator
KEFEFEAG_00373 8.1e-39 yabO J S4 domain protein
KEFEFEAG_00374 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KEFEFEAG_00375 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KEFEFEAG_00376 5.2e-170 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KEFEFEAG_00377 4e-113 S (CBS) domain
KEFEFEAG_00378 3.1e-147 tesE Q hydratase
KEFEFEAG_00379 4.7e-243 codA 3.5.4.1 F cytosine deaminase
KEFEFEAG_00380 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
KEFEFEAG_00381 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
KEFEFEAG_00382 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KEFEFEAG_00383 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KEFEFEAG_00385 2.1e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFEFEAG_00386 3.7e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
KEFEFEAG_00387 4.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KEFEFEAG_00388 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KEFEFEAG_00389 5.9e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
KEFEFEAG_00390 6e-79 L Integrase
KEFEFEAG_00392 1.5e-26 lytE M LysM domain protein
KEFEFEAG_00393 2.3e-57 tdk 2.7.1.21 F Thymidine kinase
KEFEFEAG_00395 1.5e-33 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
KEFEFEAG_00398 1.5e-11
KEFEFEAG_00404 8.6e-31 S Protein of unknown function (DUF1064)
KEFEFEAG_00405 4.3e-64 S DNA ligase (ATP) activity
KEFEFEAG_00407 3.9e-228 dnaE_2 2.7.7.7 L DNA polymerase
KEFEFEAG_00408 1.9e-39 S PD-(D/E)XK nuclease superfamily
KEFEFEAG_00409 2.4e-38 S DNA primase activity
KEFEFEAG_00410 2.1e-92 S Glycosyl hydrolases family 25
KEFEFEAG_00411 6.8e-63 S regulation of transcription, DNA-dependent
KEFEFEAG_00412 1.4e-12
KEFEFEAG_00415 4e-08
KEFEFEAG_00416 9.2e-106 fliC N bacterial-type flagellum-dependent cell motility
KEFEFEAG_00417 1.1e-67
KEFEFEAG_00418 2e-52
KEFEFEAG_00420 1.4e-57 D Phage-related minor tail protein
KEFEFEAG_00421 4.7e-79 xerH L Belongs to the 'phage' integrase family
KEFEFEAG_00424 2.7e-10 hol S COG5546 Small integral membrane protein
KEFEFEAG_00426 9.7e-08
KEFEFEAG_00428 1e-16
KEFEFEAG_00429 2.9e-31 GT2,GT4 O gp58-like protein
KEFEFEAG_00430 9e-28
KEFEFEAG_00436 4.2e-61
KEFEFEAG_00438 1.3e-49
KEFEFEAG_00439 3.7e-35
KEFEFEAG_00440 2.4e-137 gp17a S Terminase-like family
KEFEFEAG_00441 9.3e-23 1.1.98.6, 3.6.3.14, 3.6.3.15, 4.1.1.35 L Participates in initiation and elongation during chromosome replication
KEFEFEAG_00442 3.3e-22 gp17a S Terminase-like family
KEFEFEAG_00443 8.6e-17
KEFEFEAG_00448 7.2e-17 S Replication initiator protein A (RepA) N-terminus
KEFEFEAG_00449 6.2e-94 soj D CobQ CobB MinD ParA nucleotide binding domain protein
KEFEFEAG_00451 2.7e-41
KEFEFEAG_00456 1.7e-13 ard S Antirestriction protein (ArdA)
KEFEFEAG_00466 3.8e-07 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KEFEFEAG_00474 2.5e-10
KEFEFEAG_00475 7.7e-41 doc S Fic/DOC family
KEFEFEAG_00478 4e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KEFEFEAG_00479 7.8e-90 L Belongs to the 'phage' integrase family
KEFEFEAG_00481 1.5e-10 2.7.1.24 H dephospho-CoA kinase activity
KEFEFEAG_00483 6.1e-19
KEFEFEAG_00484 3.3e-18 L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KEFEFEAG_00485 7.2e-69 S hydrolase activity
KEFEFEAG_00486 5.3e-30
KEFEFEAG_00488 2.5e-97 3.6.4.12 L DnaB-like helicase C terminal domain
KEFEFEAG_00491 7.1e-112 recD 3.1.11.5 L Helix-hairpin-helix containing domain
KEFEFEAG_00494 1.5e-77 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
KEFEFEAG_00496 6e-114 pnuC H nicotinamide mononucleotide transporter
KEFEFEAG_00498 9.1e-11 nrdH O Glutaredoxin
KEFEFEAG_00506 7.1e-85 dck 2.7.1.74 F Deoxynucleoside kinase
KEFEFEAG_00514 1.7e-76 ntd 2.4.2.6 F Nucleoside
KEFEFEAG_00515 2.6e-132 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KEFEFEAG_00523 2.2e-18
KEFEFEAG_00524 4.7e-18
KEFEFEAG_00525 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
KEFEFEAG_00526 5e-244 hsdM 2.1.1.72 V type I restriction-modification system
KEFEFEAG_00527 1.8e-84 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KEFEFEAG_00528 3.8e-247 1.17.1.9, 1.18.1.2, 1.19.1.1, 1.3.1.34, 1.5.8.1, 1.5.8.2, 5.2.1.13 C NADH:flavin oxidoreductase / NADH oxidase family
KEFEFEAG_00529 5.9e-11
KEFEFEAG_00530 4.7e-55 L Transposase IS66 family
KEFEFEAG_00531 1.8e-128 V Type II restriction enzyme, methylase subunits
KEFEFEAG_00532 1.1e-125 V Pfam:Methyltransf_26
KEFEFEAG_00535 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KEFEFEAG_00536 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
KEFEFEAG_00537 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KEFEFEAG_00538 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KEFEFEAG_00539 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KEFEFEAG_00540 1.7e-84 F NUDIX domain
KEFEFEAG_00541 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
KEFEFEAG_00542 3.2e-264 L PFAM Integrase catalytic region
KEFEFEAG_00543 2e-131 2.4.1.52 GT4 M Glycosyl transferases group 1
KEFEFEAG_00544 8.6e-202 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KEFEFEAG_00545 2.5e-20 L PFAM transposase IS116 IS110 IS902
KEFEFEAG_00546 0.0 2.7.7.6 M Peptidase family M23
KEFEFEAG_00547 5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
KEFEFEAG_00548 1.1e-175 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KEFEFEAG_00549 2.1e-145 cps1D M Domain of unknown function (DUF4422)
KEFEFEAG_00550 7.4e-125 recX 2.4.1.337 GT4 S Regulatory protein RecX
KEFEFEAG_00551 4.9e-31
KEFEFEAG_00552 6.6e-34 S Protein of unknown function (DUF2922)
KEFEFEAG_00553 3.2e-153 yihY S Belongs to the UPF0761 family
KEFEFEAG_00554 1.1e-281 yjeM E Amino Acid
KEFEFEAG_00555 1e-254 E Arginine ornithine antiporter
KEFEFEAG_00556 1.7e-220 arcT 2.6.1.1 E Aminotransferase
KEFEFEAG_00557 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
KEFEFEAG_00558 5.1e-78 fld C Flavodoxin
KEFEFEAG_00559 2.3e-67 gtcA S Teichoic acid glycosylation protein
KEFEFEAG_00560 9.3e-56
KEFEFEAG_00561 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KEFEFEAG_00563 2.2e-227 yfmL L DEAD DEAH box helicase
KEFEFEAG_00564 4.5e-191 mocA S Oxidoreductase
KEFEFEAG_00565 9.1e-62 S Domain of unknown function (DUF4828)
KEFEFEAG_00566 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KEFEFEAG_00567 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KEFEFEAG_00568 1.1e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KEFEFEAG_00569 9.3e-197 S Protein of unknown function (DUF3114)
KEFEFEAG_00570 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
KEFEFEAG_00571 4.9e-120 ybhL S Belongs to the BI1 family
KEFEFEAG_00572 3.1e-21
KEFEFEAG_00573 9.1e-92 K Acetyltransferase (GNAT) family
KEFEFEAG_00574 6.4e-78 K LytTr DNA-binding domain
KEFEFEAG_00575 7.3e-69 S Protein of unknown function (DUF3021)
KEFEFEAG_00576 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KEFEFEAG_00577 4.3e-208 potD P ABC transporter
KEFEFEAG_00578 1.9e-139 potC P ABC transporter permease
KEFEFEAG_00579 4.5e-146 potB P ABC transporter permease
KEFEFEAG_00580 1.7e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KEFEFEAG_00581 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KEFEFEAG_00582 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KEFEFEAG_00583 0.0 pacL 3.6.3.8 P P-type ATPase
KEFEFEAG_00584 3.4e-85 dps P Belongs to the Dps family
KEFEFEAG_00585 2.3e-243 yagE E amino acid
KEFEFEAG_00586 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
KEFEFEAG_00587 6.2e-59 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KEFEFEAG_00588 2.5e-127 L Helix-turn-helix domain
KEFEFEAG_00589 6.7e-150 L hmm pf00665
KEFEFEAG_00590 3.2e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KEFEFEAG_00591 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
KEFEFEAG_00592 4.3e-138 IQ KR domain
KEFEFEAG_00593 3.3e-133 S membrane transporter protein
KEFEFEAG_00594 3e-96 S ABC-type cobalt transport system, permease component
KEFEFEAG_00595 1e-246 cbiO1 S ABC transporter, ATP-binding protein
KEFEFEAG_00596 1.8e-113 P Cobalt transport protein
KEFEFEAG_00597 1.6e-52 yvlA
KEFEFEAG_00598 0.0 yjcE P Sodium proton antiporter
KEFEFEAG_00600 6.7e-142 ant 2.7.7.47 S Domain of unknown function (DUF4111)
KEFEFEAG_00601 1.3e-92 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
KEFEFEAG_00602 2.8e-81 S KNTase C-terminal domain
KEFEFEAG_00603 1.3e-18
KEFEFEAG_00605 3.3e-12
KEFEFEAG_00607 7.1e-28 L Phage integrase family
KEFEFEAG_00608 2.1e-177 L PFAM Integrase catalytic region
KEFEFEAG_00609 2.9e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KEFEFEAG_00610 3.2e-56 cadX K Bacterial regulatory protein, arsR family
KEFEFEAG_00611 2.8e-95 cadD P Cadmium resistance transporter
KEFEFEAG_00612 3.6e-45
KEFEFEAG_00613 3.2e-101 L Integrase
KEFEFEAG_00614 3.5e-61 S Phage derived protein Gp49-like (DUF891)
KEFEFEAG_00615 3.7e-39 K Helix-turn-helix domain
KEFEFEAG_00624 6.9e-09 S HTH domain
KEFEFEAG_00625 2.1e-177 L PFAM Integrase catalytic region
KEFEFEAG_00626 6.1e-244 fucP G Major Facilitator Superfamily
KEFEFEAG_00627 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KEFEFEAG_00628 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KEFEFEAG_00629 3.6e-168 murB 1.3.1.98 M Cell wall formation
KEFEFEAG_00630 1.1e-69 yqeY S YqeY-like protein
KEFEFEAG_00631 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KEFEFEAG_00632 9.1e-265 glnPH2 P ABC transporter permease
KEFEFEAG_00633 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KEFEFEAG_00634 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KEFEFEAG_00635 1e-164 yniA G Phosphotransferase enzyme family
KEFEFEAG_00636 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KEFEFEAG_00637 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KEFEFEAG_00638 1.2e-52
KEFEFEAG_00639 2.7e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KEFEFEAG_00640 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
KEFEFEAG_00641 4.1e-56
KEFEFEAG_00643 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KEFEFEAG_00645 4.7e-199 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KEFEFEAG_00646 4.1e-275 pipD E Dipeptidase
KEFEFEAG_00647 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KEFEFEAG_00648 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KEFEFEAG_00649 0.0 dnaK O Heat shock 70 kDa protein
KEFEFEAG_00650 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KEFEFEAG_00651 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KEFEFEAG_00652 5.8e-64
KEFEFEAG_00653 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KEFEFEAG_00654 2e-126 ybbR S YbbR-like protein
KEFEFEAG_00655 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KEFEFEAG_00656 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KEFEFEAG_00657 8.7e-53
KEFEFEAG_00658 0.0 oatA I Acyltransferase
KEFEFEAG_00659 2.3e-81 K Transcriptional regulator
KEFEFEAG_00660 2e-149 XK27_02985 S Cof-like hydrolase
KEFEFEAG_00661 2.8e-79 lytE M Lysin motif
KEFEFEAG_00663 1.5e-132 K response regulator
KEFEFEAG_00664 2.6e-272 yclK 2.7.13.3 T Histidine kinase
KEFEFEAG_00665 2.6e-155 glcU U sugar transport
KEFEFEAG_00666 2e-93 lacA 2.3.1.79 S Transferase hexapeptide repeat
KEFEFEAG_00667 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
KEFEFEAG_00668 1.3e-28
KEFEFEAG_00669 4.8e-33 xylR GK ROK family
KEFEFEAG_00670 6.8e-99 xylR GK ROK family
KEFEFEAG_00671 1.8e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
KEFEFEAG_00672 8.1e-154 KT YcbB domain
KEFEFEAG_00673 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KEFEFEAG_00674 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
KEFEFEAG_00675 5.8e-155 EG EamA-like transporter family
KEFEFEAG_00676 7.8e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KEFEFEAG_00677 1.6e-197 EGP Major facilitator Superfamily
KEFEFEAG_00678 2.1e-88 ymdB S Macro domain protein
KEFEFEAG_00679 8.4e-111 K Helix-turn-helix domain
KEFEFEAG_00680 0.0 pepO 3.4.24.71 O Peptidase family M13
KEFEFEAG_00681 5.1e-47
KEFEFEAG_00682 4.2e-242 S Putative metallopeptidase domain
KEFEFEAG_00683 3e-204 3.1.3.1 S associated with various cellular activities
KEFEFEAG_00684 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KEFEFEAG_00685 1.6e-64 yeaO S Protein of unknown function, DUF488
KEFEFEAG_00687 5.4e-116 yrkL S Flavodoxin-like fold
KEFEFEAG_00688 9.5e-55
KEFEFEAG_00689 2e-15 S Domain of unknown function (DUF4767)
KEFEFEAG_00690 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KEFEFEAG_00691 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KEFEFEAG_00692 6.9e-49
KEFEFEAG_00693 4.9e-204 nrnB S DHHA1 domain
KEFEFEAG_00694 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
KEFEFEAG_00695 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
KEFEFEAG_00696 2e-106 NU mannosyl-glycoprotein
KEFEFEAG_00697 2.3e-142 S Putative ABC-transporter type IV
KEFEFEAG_00698 7.8e-272 S ABC transporter, ATP-binding protein
KEFEFEAG_00699 8.2e-48
KEFEFEAG_00700 5.3e-72 K Transcriptional regulator, TetR family
KEFEFEAG_00701 4.3e-13 K Transcriptional regulator, TetR family
KEFEFEAG_00703 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KEFEFEAG_00704 3e-86
KEFEFEAG_00705 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KEFEFEAG_00706 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KEFEFEAG_00707 4.2e-261 nox C NADH oxidase
KEFEFEAG_00708 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
KEFEFEAG_00709 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
KEFEFEAG_00710 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
KEFEFEAG_00711 3.8e-167 yvgN C Aldo keto reductase
KEFEFEAG_00712 6.6e-136 puuD S peptidase C26
KEFEFEAG_00713 1.7e-128 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KEFEFEAG_00714 4.1e-212 yfeO P Voltage gated chloride channel
KEFEFEAG_00715 8.7e-221 sptS 2.7.13.3 T Histidine kinase
KEFEFEAG_00716 2.8e-117 K response regulator
KEFEFEAG_00717 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
KEFEFEAG_00718 1.7e-71
KEFEFEAG_00719 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KEFEFEAG_00720 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KEFEFEAG_00721 1.1e-256 malT G Major Facilitator
KEFEFEAG_00722 3.9e-116 L Belongs to the 'phage' integrase family
KEFEFEAG_00724 3.9e-09 S Helix-turn-helix domain
KEFEFEAG_00727 5.5e-35 S hydrolase activity
KEFEFEAG_00728 6e-76 S Virulence-associated protein E
KEFEFEAG_00730 3.1e-11 S head-tail joining protein
KEFEFEAG_00731 3.4e-31 L HNH endonuclease
KEFEFEAG_00732 2.9e-26 terS L Phage terminase, small subunit
KEFEFEAG_00733 2e-199 terL S overlaps another CDS with the same product name
KEFEFEAG_00734 5.2e-140 S Phage portal protein
KEFEFEAG_00735 9e-191 S Caudovirus prohead serine protease
KEFEFEAG_00736 5.7e-17 S Phage gp6-like head-tail connector protein
KEFEFEAG_00737 4.5e-25
KEFEFEAG_00738 1.1e-07
KEFEFEAG_00740 1.9e-159 yjcE P Sodium proton antiporter
KEFEFEAG_00741 1.6e-74 yjcE P Sodium proton antiporter
KEFEFEAG_00742 5.2e-56
KEFEFEAG_00744 1.7e-84
KEFEFEAG_00745 0.0 copA 3.6.3.54 P P-type ATPase
KEFEFEAG_00746 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KEFEFEAG_00747 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KEFEFEAG_00748 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KEFEFEAG_00749 7.7e-130 ponA V Beta-lactamase enzyme family
KEFEFEAG_00750 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
KEFEFEAG_00751 6.3e-216 uhpT EGP Major facilitator Superfamily
KEFEFEAG_00752 1.6e-257 ytjP 3.5.1.18 E Dipeptidase
KEFEFEAG_00753 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
KEFEFEAG_00754 4.8e-179 yfeX P Peroxidase
KEFEFEAG_00755 1.4e-169 lsa S ABC transporter
KEFEFEAG_00756 7.2e-135 I alpha/beta hydrolase fold
KEFEFEAG_00757 8e-180 MA20_14895 S Conserved hypothetical protein 698
KEFEFEAG_00758 3.5e-67 S NADPH-dependent FMN reductase
KEFEFEAG_00759 8.7e-09 S NADPH-dependent FMN reductase
KEFEFEAG_00760 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KEFEFEAG_00761 6.2e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KEFEFEAG_00762 1e-232 mntH P H( )-stimulated, divalent metal cation uptake system
KEFEFEAG_00763 3.2e-79 Q Methyltransferase
KEFEFEAG_00764 5.3e-116 ktrA P domain protein
KEFEFEAG_00765 6.5e-238 ktrB P Potassium uptake protein
KEFEFEAG_00766 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KEFEFEAG_00767 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KEFEFEAG_00768 2.4e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KEFEFEAG_00769 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KEFEFEAG_00770 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KEFEFEAG_00772 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KEFEFEAG_00773 2e-239 glpT G Major Facilitator Superfamily
KEFEFEAG_00774 8.8e-15
KEFEFEAG_00776 4e-170 whiA K May be required for sporulation
KEFEFEAG_00777 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KEFEFEAG_00778 1.1e-161 rapZ S Displays ATPase and GTPase activities
KEFEFEAG_00779 5.4e-245 steT E amino acid
KEFEFEAG_00780 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KEFEFEAG_00781 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KEFEFEAG_00782 1.5e-13
KEFEFEAG_00783 2.3e-116 yfbR S HD containing hydrolase-like enzyme
KEFEFEAG_00784 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KEFEFEAG_00785 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
KEFEFEAG_00786 1.3e-157 aatB ET PFAM extracellular solute-binding protein, family 3
KEFEFEAG_00787 8.4e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KEFEFEAG_00788 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KEFEFEAG_00789 1.7e-162 lutA C Cysteine-rich domain
KEFEFEAG_00790 7.5e-288 lutB C 4Fe-4S dicluster domain
KEFEFEAG_00791 4.3e-135 yrjD S LUD domain
KEFEFEAG_00792 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KEFEFEAG_00793 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KEFEFEAG_00794 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KEFEFEAG_00795 3.9e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KEFEFEAG_00796 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KEFEFEAG_00797 3.1e-32 KT PspC domain protein
KEFEFEAG_00798 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KEFEFEAG_00799 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KEFEFEAG_00800 4.2e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KEFEFEAG_00801 1.3e-114 comFC S Competence protein
KEFEFEAG_00802 1.4e-256 comFA L Helicase C-terminal domain protein
KEFEFEAG_00803 2.9e-111 yvyE 3.4.13.9 S YigZ family
KEFEFEAG_00804 1.1e-235 EGP Major facilitator Superfamily
KEFEFEAG_00805 7.4e-68 rmaI K Transcriptional regulator
KEFEFEAG_00806 9.2e-40
KEFEFEAG_00807 0.0 ydaO E amino acid
KEFEFEAG_00808 7.3e-305 ybeC E amino acid
KEFEFEAG_00809 8.2e-82 S YbaK proline--tRNA ligase associated domain protein
KEFEFEAG_00810 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KEFEFEAG_00811 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KEFEFEAG_00813 1.4e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KEFEFEAG_00814 0.0 uup S ABC transporter, ATP-binding protein
KEFEFEAG_00815 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KEFEFEAG_00816 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
KEFEFEAG_00817 2.3e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KEFEFEAG_00818 1.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KEFEFEAG_00819 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KEFEFEAG_00820 4.7e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEFEFEAG_00821 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KEFEFEAG_00822 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KEFEFEAG_00823 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KEFEFEAG_00824 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KEFEFEAG_00825 1.2e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KEFEFEAG_00826 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KEFEFEAG_00827 3.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KEFEFEAG_00828 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
KEFEFEAG_00829 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KEFEFEAG_00830 5.9e-58 yabA L Involved in initiation control of chromosome replication
KEFEFEAG_00831 8.2e-185 holB 2.7.7.7 L DNA polymerase III
KEFEFEAG_00832 7.6e-52 yaaQ S Cyclic-di-AMP receptor
KEFEFEAG_00833 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KEFEFEAG_00834 9.7e-39 S Protein of unknown function (DUF2508)
KEFEFEAG_00835 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KEFEFEAG_00836 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KEFEFEAG_00837 6.2e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KEFEFEAG_00838 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KEFEFEAG_00839 3.4e-35 nrdH O Glutaredoxin
KEFEFEAG_00840 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEFEFEAG_00841 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KEFEFEAG_00842 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KEFEFEAG_00843 6.4e-126 S Putative adhesin
KEFEFEAG_00844 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
KEFEFEAG_00845 4e-56 K transcriptional regulator PadR family
KEFEFEAG_00846 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KEFEFEAG_00848 1.5e-48
KEFEFEAG_00849 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KEFEFEAG_00850 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KEFEFEAG_00851 1.5e-172 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KEFEFEAG_00852 1.9e-26 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KEFEFEAG_00853 5.5e-220 M Glycosyl transferase family group 2
KEFEFEAG_00855 1.3e-226 aadAT EK Aminotransferase, class I
KEFEFEAG_00856 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KEFEFEAG_00857 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KEFEFEAG_00858 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
KEFEFEAG_00859 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KEFEFEAG_00860 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KEFEFEAG_00861 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEFEFEAG_00862 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KEFEFEAG_00863 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEFEFEAG_00864 1.7e-207 yacL S domain protein
KEFEFEAG_00865 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KEFEFEAG_00866 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KEFEFEAG_00867 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
KEFEFEAG_00868 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KEFEFEAG_00869 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
KEFEFEAG_00870 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KEFEFEAG_00871 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KEFEFEAG_00872 2.4e-119 tcyB E ABC transporter
KEFEFEAG_00873 4.2e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KEFEFEAG_00874 3.1e-169 I alpha/beta hydrolase fold
KEFEFEAG_00875 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KEFEFEAG_00876 0.0 S Bacterial membrane protein, YfhO
KEFEFEAG_00877 3.8e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KEFEFEAG_00878 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KEFEFEAG_00880 5.6e-85 ydcK S Belongs to the SprT family
KEFEFEAG_00881 0.0 yhgF K Tex-like protein N-terminal domain protein
KEFEFEAG_00882 5.1e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KEFEFEAG_00883 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KEFEFEAG_00884 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
KEFEFEAG_00885 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KEFEFEAG_00886 6.1e-198 XK27_09615 S reductase
KEFEFEAG_00887 6e-100 nqr 1.5.1.36 S reductase
KEFEFEAG_00889 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KEFEFEAG_00890 9.3e-181 K Transcriptional regulator, LacI family
KEFEFEAG_00891 2e-258 G Major Facilitator
KEFEFEAG_00892 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KEFEFEAG_00893 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KEFEFEAG_00894 1.9e-214 G Major Facilitator
KEFEFEAG_00895 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KEFEFEAG_00896 7.1e-274 M domain protein
KEFEFEAG_00897 7.9e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
KEFEFEAG_00898 1.8e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
KEFEFEAG_00899 2.2e-72
KEFEFEAG_00900 1.3e-177 fecB P Periplasmic binding protein
KEFEFEAG_00901 1.4e-139 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
KEFEFEAG_00902 1.8e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KEFEFEAG_00903 1.5e-77 S Flavodoxin
KEFEFEAG_00904 3.7e-64 moaE 2.8.1.12 H MoaE protein
KEFEFEAG_00905 4.9e-35 moaD 2.8.1.12 H ThiS family
KEFEFEAG_00906 3.9e-218 narK P Transporter, major facilitator family protein
KEFEFEAG_00907 2.9e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
KEFEFEAG_00908 3.6e-182
KEFEFEAG_00909 1.6e-18
KEFEFEAG_00910 2.3e-116 nreC K PFAM regulatory protein LuxR
KEFEFEAG_00911 1e-190 comP 2.7.13.3 F Sensor histidine kinase
KEFEFEAG_00912 3e-44
KEFEFEAG_00913 2.3e-104 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KEFEFEAG_00914 5.1e-84 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KEFEFEAG_00915 8.5e-229 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
KEFEFEAG_00916 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KEFEFEAG_00917 8.8e-187 moeB 2.7.7.73, 2.7.7.80 H ThiF family
KEFEFEAG_00918 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KEFEFEAG_00919 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
KEFEFEAG_00920 6.9e-96 narJ C nitrate reductase molybdenum cofactor assembly chaperone
KEFEFEAG_00921 7.6e-126 narI 1.7.5.1 C Nitrate reductase
KEFEFEAG_00923 2.1e-28 cspA K Cold shock protein
KEFEFEAG_00925 1.2e-278 L Recombinase
KEFEFEAG_00926 1.9e-38 S Protein of unknown function (DUF2815)
KEFEFEAG_00927 3.8e-199 L Protein of unknown function (DUF2800)
KEFEFEAG_00928 8.8e-27
KEFEFEAG_00930 2.7e-150
KEFEFEAG_00931 4.4e-25
KEFEFEAG_00932 3.7e-227
KEFEFEAG_00933 1.3e-35 K Cro/C1-type HTH DNA-binding domain
KEFEFEAG_00934 2.3e-41 mod 2.1.1.72, 3.1.21.5 L DNA methylase
KEFEFEAG_00935 2.8e-171 mod 2.1.1.72, 3.1.21.5 L DNA methylase
KEFEFEAG_00936 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
KEFEFEAG_00937 3.3e-207 K DNA binding
KEFEFEAG_00938 0.0 L helicase activity
KEFEFEAG_00940 9.4e-10
KEFEFEAG_00941 1.7e-171 2.7.7.65 T GGDEF domain
KEFEFEAG_00942 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
KEFEFEAG_00943 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KEFEFEAG_00944 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
KEFEFEAG_00945 2e-92 folT S ECF transporter, substrate-specific component
KEFEFEAG_00946 0.0 pepN 3.4.11.2 E aminopeptidase
KEFEFEAG_00947 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
KEFEFEAG_00948 9.8e-255 pepC 3.4.22.40 E aminopeptidase
KEFEFEAG_00949 6.5e-210 EGP Major facilitator Superfamily
KEFEFEAG_00950 1.8e-229
KEFEFEAG_00951 5.5e-26 K Transcriptional regulator, HxlR family
KEFEFEAG_00952 1.6e-43 K Transcriptional regulator, HxlR family
KEFEFEAG_00953 1.4e-107 XK27_02070 S Nitroreductase family
KEFEFEAG_00954 2.5e-52 hxlR K Transcriptional regulator, HxlR family
KEFEFEAG_00955 3e-119 GM NmrA-like family
KEFEFEAG_00956 1.7e-70 elaA S Gnat family
KEFEFEAG_00957 1.8e-39 S Cytochrome B5
KEFEFEAG_00958 5.4e-09 S Cytochrome B5
KEFEFEAG_00959 7.8e-41 S Cytochrome B5
KEFEFEAG_00960 6.7e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
KEFEFEAG_00962 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KEFEFEAG_00963 3.2e-47 rpsJ J Involved in the binding of tRNA to the ribosomes
KEFEFEAG_00964 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KEFEFEAG_00965 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
KEFEFEAG_00966 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KEFEFEAG_00967 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KEFEFEAG_00968 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KEFEFEAG_00969 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KEFEFEAG_00970 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KEFEFEAG_00971 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KEFEFEAG_00972 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
KEFEFEAG_00973 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KEFEFEAG_00974 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KEFEFEAG_00975 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KEFEFEAG_00976 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KEFEFEAG_00977 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KEFEFEAG_00978 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KEFEFEAG_00979 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KEFEFEAG_00980 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KEFEFEAG_00981 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KEFEFEAG_00982 2.9e-24 rpmD J Ribosomal protein L30
KEFEFEAG_00983 8.9e-64 rplO J Binds to the 23S rRNA
KEFEFEAG_00984 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KEFEFEAG_00985 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KEFEFEAG_00986 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KEFEFEAG_00987 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KEFEFEAG_00988 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KEFEFEAG_00989 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KEFEFEAG_00990 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEFEFEAG_00991 1.1e-62 rplQ J Ribosomal protein L17
KEFEFEAG_00992 3e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEFEFEAG_00993 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEFEFEAG_00994 5.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KEFEFEAG_00995 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KEFEFEAG_00996 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KEFEFEAG_00997 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KEFEFEAG_00998 2.8e-35
KEFEFEAG_00999 7.1e-72 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KEFEFEAG_01000 2.6e-164 ykoT GT2 M Glycosyl transferase family 2
KEFEFEAG_01002 6.3e-55 S integral membrane protein
KEFEFEAG_01003 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KEFEFEAG_01004 8.3e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KEFEFEAG_01005 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KEFEFEAG_01006 3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KEFEFEAG_01007 1.6e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KEFEFEAG_01008 0.0 csd1 3.5.1.28 G domain, Protein
KEFEFEAG_01009 1.1e-163 yueF S AI-2E family transporter
KEFEFEAG_01010 7.1e-230 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KEFEFEAG_01011 1.3e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KEFEFEAG_01012 1.7e-123 L Belongs to the 'phage' integrase family
KEFEFEAG_01013 1.9e-10
KEFEFEAG_01014 1.8e-38 S D5 N terminal like
KEFEFEAG_01018 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KEFEFEAG_01019 1.9e-80 3.1.21.3 V Type I restriction modification DNA specificity domain
KEFEFEAG_01020 6e-125 L Belongs to the 'phage' integrase family
KEFEFEAG_01021 1.5e-76 3.1.21.3 V Type I restriction modification DNA specificity domain
KEFEFEAG_01022 2.1e-219 hsdM 2.1.1.72 V type I restriction-modification system
KEFEFEAG_01029 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KEFEFEAG_01030 1.4e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KEFEFEAG_01031 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KEFEFEAG_01032 2.8e-31 yajC U Preprotein translocase
KEFEFEAG_01033 9e-190 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KEFEFEAG_01034 3.8e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KEFEFEAG_01035 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KEFEFEAG_01036 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KEFEFEAG_01037 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KEFEFEAG_01038 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
KEFEFEAG_01039 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KEFEFEAG_01040 5.6e-228 cinA 3.5.1.42 S Belongs to the CinA family
KEFEFEAG_01041 6.3e-230 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KEFEFEAG_01042 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
KEFEFEAG_01043 2e-180 galR K Transcriptional regulator
KEFEFEAG_01044 7.6e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KEFEFEAG_01045 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KEFEFEAG_01046 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
KEFEFEAG_01047 1.5e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
KEFEFEAG_01048 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
KEFEFEAG_01049 9.1e-36
KEFEFEAG_01050 5.9e-52
KEFEFEAG_01051 2.3e-204
KEFEFEAG_01052 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KEFEFEAG_01053 8.9e-136 pnuC H nicotinamide mononucleotide transporter
KEFEFEAG_01054 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
KEFEFEAG_01055 3.2e-124 K response regulator
KEFEFEAG_01056 1.3e-179 T PhoQ Sensor
KEFEFEAG_01057 2.6e-135 macB2 V ABC transporter, ATP-binding protein
KEFEFEAG_01058 0.0 ysaB V FtsX-like permease family
KEFEFEAG_01059 2.3e-66 yunF F Protein of unknown function DUF72
KEFEFEAG_01061 1e-130 cobB K SIR2 family
KEFEFEAG_01062 1.6e-177
KEFEFEAG_01063 8e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KEFEFEAG_01064 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KEFEFEAG_01065 1.3e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KEFEFEAG_01066 5.5e-183 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KEFEFEAG_01067 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
KEFEFEAG_01068 0.0 helD 3.6.4.12 L DNA helicase
KEFEFEAG_01069 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KEFEFEAG_01071 3.1e-256 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KEFEFEAG_01072 5.2e-265 yfnA E amino acid
KEFEFEAG_01073 8.4e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KEFEFEAG_01074 4.3e-43 1.3.5.4 S FMN binding
KEFEFEAG_01075 1.2e-219 norA EGP Major facilitator Superfamily
KEFEFEAG_01076 8.6e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KEFEFEAG_01077 2.5e-277 pepV 3.5.1.18 E dipeptidase PepV
KEFEFEAG_01078 4.3e-86 uspA T Belongs to the universal stress protein A family
KEFEFEAG_01079 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KEFEFEAG_01080 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
KEFEFEAG_01081 3.8e-113
KEFEFEAG_01082 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
KEFEFEAG_01083 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KEFEFEAG_01084 2.1e-32
KEFEFEAG_01085 2.6e-118 S CAAX protease self-immunity
KEFEFEAG_01086 1.9e-43
KEFEFEAG_01088 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KEFEFEAG_01089 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KEFEFEAG_01090 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
KEFEFEAG_01091 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KEFEFEAG_01092 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
KEFEFEAG_01093 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
KEFEFEAG_01094 1.8e-43
KEFEFEAG_01095 1.2e-32
KEFEFEAG_01097 1e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KEFEFEAG_01098 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KEFEFEAG_01099 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KEFEFEAG_01100 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KEFEFEAG_01101 3.5e-40 yheA S Belongs to the UPF0342 family
KEFEFEAG_01102 1.8e-220 yhaO L Ser Thr phosphatase family protein
KEFEFEAG_01103 0.0 L AAA domain
KEFEFEAG_01104 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KEFEFEAG_01106 1.2e-76 hit FG histidine triad
KEFEFEAG_01107 3.9e-136 ecsA V ABC transporter, ATP-binding protein
KEFEFEAG_01108 1.3e-216 ecsB U ABC transporter
KEFEFEAG_01109 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KEFEFEAG_01110 7.7e-27 S YSIRK type signal peptide
KEFEFEAG_01111 3.8e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
KEFEFEAG_01112 9.5e-256 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
KEFEFEAG_01113 3.3e-144 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KEFEFEAG_01114 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KEFEFEAG_01115 2e-183 iolS C Aldo keto reductase
KEFEFEAG_01116 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
KEFEFEAG_01117 7.5e-58 ytzB S Small secreted protein
KEFEFEAG_01118 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KEFEFEAG_01119 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KEFEFEAG_01120 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
KEFEFEAG_01121 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
KEFEFEAG_01122 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KEFEFEAG_01123 1.9e-119 ybhL S Belongs to the BI1 family
KEFEFEAG_01124 2e-115 yoaK S Protein of unknown function (DUF1275)
KEFEFEAG_01125 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KEFEFEAG_01126 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KEFEFEAG_01127 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KEFEFEAG_01128 5.6e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KEFEFEAG_01129 1.4e-203 dnaB L replication initiation and membrane attachment
KEFEFEAG_01130 1.1e-170 dnaI L Primosomal protein DnaI
KEFEFEAG_01131 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KEFEFEAG_01132 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KEFEFEAG_01133 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KEFEFEAG_01134 1.8e-95 yqeG S HAD phosphatase, family IIIA
KEFEFEAG_01135 4.8e-218 yqeH S Ribosome biogenesis GTPase YqeH
KEFEFEAG_01136 1.9e-47 yhbY J RNA-binding protein
KEFEFEAG_01137 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KEFEFEAG_01138 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KEFEFEAG_01139 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KEFEFEAG_01140 1.7e-139 yqeM Q Methyltransferase
KEFEFEAG_01141 2.1e-213 ylbM S Belongs to the UPF0348 family
KEFEFEAG_01142 2.9e-99 yceD S Uncharacterized ACR, COG1399
KEFEFEAG_01143 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KEFEFEAG_01144 1.5e-121 K response regulator
KEFEFEAG_01145 4.1e-278 arlS 2.7.13.3 T Histidine kinase
KEFEFEAG_01146 7.4e-267 yjeM E Amino Acid
KEFEFEAG_01147 9.8e-231 V MatE
KEFEFEAG_01148 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KEFEFEAG_01149 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KEFEFEAG_01150 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KEFEFEAG_01151 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KEFEFEAG_01152 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KEFEFEAG_01153 9.7e-58 yodB K Transcriptional regulator, HxlR family
KEFEFEAG_01154 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KEFEFEAG_01155 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KEFEFEAG_01156 5.6e-115 rlpA M PFAM NLP P60 protein
KEFEFEAG_01157 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
KEFEFEAG_01158 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KEFEFEAG_01160 9.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
KEFEFEAG_01161 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KEFEFEAG_01162 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KEFEFEAG_01163 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KEFEFEAG_01164 1.5e-172 malR K Transcriptional regulator, LacI family
KEFEFEAG_01165 2.4e-212 phbA 2.3.1.9 I Belongs to the thiolase family
KEFEFEAG_01167 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KEFEFEAG_01168 2.3e-176 ABC-SBP S ABC transporter
KEFEFEAG_01169 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
KEFEFEAG_01170 9.6e-215 htrA 3.4.21.107 O serine protease
KEFEFEAG_01171 4.5e-154 vicX 3.1.26.11 S domain protein
KEFEFEAG_01172 2.7e-149 yycI S YycH protein
KEFEFEAG_01173 2.1e-246 yycH S YycH protein
KEFEFEAG_01174 0.0 vicK 2.7.13.3 T Histidine kinase
KEFEFEAG_01175 6.8e-130 K response regulator
KEFEFEAG_01177 2.1e-310 lmrA 3.6.3.44 V ABC transporter
KEFEFEAG_01178 1.2e-73 K helix_turn_helix multiple antibiotic resistance protein
KEFEFEAG_01180 7.9e-132 L Integrase core domain
KEFEFEAG_01181 4.5e-71 L Integrase core domain
KEFEFEAG_01182 1.6e-126 O Bacterial dnaA protein
KEFEFEAG_01183 9.8e-09 K DNA-binding helix-turn-helix protein
KEFEFEAG_01184 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KEFEFEAG_01185 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
KEFEFEAG_01186 4.2e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KEFEFEAG_01187 3.1e-103 metI P ABC transporter permease
KEFEFEAG_01188 5.7e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KEFEFEAG_01189 5.4e-253 clcA P chloride
KEFEFEAG_01190 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KEFEFEAG_01191 4.5e-104 proW P ABC transporter, permease protein
KEFEFEAG_01192 5.1e-139 proV E ABC transporter, ATP-binding protein
KEFEFEAG_01193 6.3e-109 proWZ P ABC transporter permease
KEFEFEAG_01194 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
KEFEFEAG_01195 2.6e-74 K Transcriptional regulator
KEFEFEAG_01196 4.8e-154 1.6.5.2 GM NAD(P)H-binding
KEFEFEAG_01198 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
KEFEFEAG_01199 0.0 cadA P P-type ATPase
KEFEFEAG_01200 4.2e-88 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
KEFEFEAG_01201 1.3e-298 2.1.1.72 V type I restriction-modification system
KEFEFEAG_01202 1.1e-54 yhaI S Protein of unknown function (DUF805)
KEFEFEAG_01203 1.1e-43
KEFEFEAG_01204 0.0 nylA 3.5.1.4 J Belongs to the amidase family
KEFEFEAG_01205 4.2e-47
KEFEFEAG_01206 2.2e-96 K Acetyltransferase (GNAT) domain
KEFEFEAG_01207 5.9e-296 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KEFEFEAG_01208 9e-229 gntT EG Gluconate
KEFEFEAG_01209 2e-183 K Transcriptional regulator, LacI family
KEFEFEAG_01210 7e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KEFEFEAG_01211 3.2e-95
KEFEFEAG_01212 2.1e-25
KEFEFEAG_01213 1.3e-61 asp S Asp23 family, cell envelope-related function
KEFEFEAG_01214 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
KEFEFEAG_01216 2.7e-49
KEFEFEAG_01217 1.6e-67 yqkB S Belongs to the HesB IscA family
KEFEFEAG_01218 1.3e-99 maa 2.3.1.79 S Maltose O-acetyltransferase
KEFEFEAG_01219 1.4e-158 ytbE 1.1.1.346 S Aldo keto reductase
KEFEFEAG_01220 1.5e-208 araR K Transcriptional regulator
KEFEFEAG_01221 9.7e-83 usp6 T universal stress protein
KEFEFEAG_01222 1.7e-45
KEFEFEAG_01223 1.3e-243 rarA L recombination factor protein RarA
KEFEFEAG_01224 2.7e-85 yueI S Protein of unknown function (DUF1694)
KEFEFEAG_01225 1.5e-21
KEFEFEAG_01226 1.8e-74 4.4.1.5 E Glyoxalase
KEFEFEAG_01227 2.5e-138 S Membrane
KEFEFEAG_01228 2.7e-140 S Belongs to the UPF0246 family
KEFEFEAG_01229 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KEFEFEAG_01230 4.4e-263 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KEFEFEAG_01231 1.1e-96 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KEFEFEAG_01232 2e-184 gadC E amino acid
KEFEFEAG_01233 1.5e-269 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
KEFEFEAG_01234 1.4e-139 IQ reductase
KEFEFEAG_01235 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
KEFEFEAG_01236 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KEFEFEAG_01237 1.1e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KEFEFEAG_01238 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KEFEFEAG_01239 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KEFEFEAG_01240 8.1e-202 camS S sex pheromone
KEFEFEAG_01241 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KEFEFEAG_01242 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KEFEFEAG_01243 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KEFEFEAG_01244 5.1e-187 yegS 2.7.1.107 G Lipid kinase
KEFEFEAG_01245 2.1e-260 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KEFEFEAG_01246 4.4e-242 yagE E amino acid
KEFEFEAG_01247 4.5e-140 aroD S Serine hydrolase (FSH1)
KEFEFEAG_01248 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
KEFEFEAG_01249 5.2e-167 GK ROK family
KEFEFEAG_01250 0.0 tetP J elongation factor G
KEFEFEAG_01251 5.1e-81 uspA T universal stress protein
KEFEFEAG_01252 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
KEFEFEAG_01253 7.1e-63
KEFEFEAG_01254 5.2e-14
KEFEFEAG_01255 1.4e-212 EGP Major facilitator Superfamily
KEFEFEAG_01256 1.3e-257 G PTS system Galactitol-specific IIC component
KEFEFEAG_01257 2.6e-180 1.6.5.5 C Zinc-binding dehydrogenase
KEFEFEAG_01258 1.1e-161
KEFEFEAG_01259 1e-72 K Transcriptional regulator
KEFEFEAG_01260 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KEFEFEAG_01261 1.6e-105 ypsA S Belongs to the UPF0398 family
KEFEFEAG_01262 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KEFEFEAG_01263 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KEFEFEAG_01264 2e-161 EG EamA-like transporter family
KEFEFEAG_01265 3e-125 dnaD L DnaD domain protein
KEFEFEAG_01266 1.4e-84 ypmB S Protein conserved in bacteria
KEFEFEAG_01267 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KEFEFEAG_01268 5.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KEFEFEAG_01269 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KEFEFEAG_01270 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KEFEFEAG_01271 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KEFEFEAG_01272 3.8e-87 S Protein of unknown function (DUF1440)
KEFEFEAG_01273 4.1e-43 yrzL S Belongs to the UPF0297 family
KEFEFEAG_01274 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KEFEFEAG_01275 6.1e-48 yrzB S Belongs to the UPF0473 family
KEFEFEAG_01276 1e-85 cvpA S Colicin V production protein
KEFEFEAG_01277 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KEFEFEAG_01278 6.1e-54 trxA O Belongs to the thioredoxin family
KEFEFEAG_01279 1.3e-96 yslB S Protein of unknown function (DUF2507)
KEFEFEAG_01280 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KEFEFEAG_01281 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KEFEFEAG_01282 4.4e-94 S Phosphoesterase
KEFEFEAG_01283 3.6e-76 ykuL S (CBS) domain
KEFEFEAG_01284 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
KEFEFEAG_01285 3.4e-147 ykuT M mechanosensitive ion channel
KEFEFEAG_01286 3.6e-36 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KEFEFEAG_01287 3.5e-26
KEFEFEAG_01288 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KEFEFEAG_01289 2.9e-182 ccpA K catabolite control protein A
KEFEFEAG_01290 1.9e-134
KEFEFEAG_01291 3.5e-132 yebC K Transcriptional regulatory protein
KEFEFEAG_01292 3.7e-18 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KEFEFEAG_01293 2.5e-234 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KEFEFEAG_01294 1.1e-124 srtA 3.4.22.70 M sortase family
KEFEFEAG_01295 8.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
KEFEFEAG_01296 1.2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KEFEFEAG_01297 4.6e-41 rpmE2 J Ribosomal protein L31
KEFEFEAG_01298 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KEFEFEAG_01299 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KEFEFEAG_01300 8.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KEFEFEAG_01301 3e-66 ywiB S Domain of unknown function (DUF1934)
KEFEFEAG_01302 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
KEFEFEAG_01303 1.1e-269 ywfO S HD domain protein
KEFEFEAG_01304 2.5e-147 yxeH S hydrolase
KEFEFEAG_01305 2.1e-49
KEFEFEAG_01306 3.3e-83
KEFEFEAG_01307 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
KEFEFEAG_01308 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
KEFEFEAG_01309 2.9e-34
KEFEFEAG_01310 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KEFEFEAG_01311 9.9e-261 yfnA E amino acid
KEFEFEAG_01312 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KEFEFEAG_01313 1.5e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KEFEFEAG_01314 2e-39 ylqC S Belongs to the UPF0109 family
KEFEFEAG_01315 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KEFEFEAG_01316 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KEFEFEAG_01317 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KEFEFEAG_01318 1.4e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KEFEFEAG_01319 0.0 smc D Required for chromosome condensation and partitioning
KEFEFEAG_01320 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KEFEFEAG_01321 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KEFEFEAG_01322 4e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KEFEFEAG_01323 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KEFEFEAG_01324 0.0 yloV S DAK2 domain fusion protein YloV
KEFEFEAG_01325 4.7e-58 asp S Asp23 family, cell envelope-related function
KEFEFEAG_01326 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KEFEFEAG_01327 1.7e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
KEFEFEAG_01328 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KEFEFEAG_01329 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KEFEFEAG_01330 0.0 KLT serine threonine protein kinase
KEFEFEAG_01331 2.9e-131 stp 3.1.3.16 T phosphatase
KEFEFEAG_01332 2.1e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KEFEFEAG_01333 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KEFEFEAG_01334 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KEFEFEAG_01335 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KEFEFEAG_01336 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KEFEFEAG_01337 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KEFEFEAG_01338 1.7e-54
KEFEFEAG_01339 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
KEFEFEAG_01340 3.3e-77 argR K Regulates arginine biosynthesis genes
KEFEFEAG_01341 6.9e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KEFEFEAG_01342 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KEFEFEAG_01343 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KEFEFEAG_01344 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KEFEFEAG_01345 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KEFEFEAG_01346 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KEFEFEAG_01347 2.2e-70 yqhY S Asp23 family, cell envelope-related function
KEFEFEAG_01348 1.7e-114 J 2'-5' RNA ligase superfamily
KEFEFEAG_01349 5.1e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KEFEFEAG_01350 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KEFEFEAG_01351 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KEFEFEAG_01352 1.6e-54 ysxB J Cysteine protease Prp
KEFEFEAG_01353 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
KEFEFEAG_01354 8.3e-111 K Transcriptional regulator
KEFEFEAG_01358 2.5e-89 dut S Protein conserved in bacteria
KEFEFEAG_01359 6.6e-174
KEFEFEAG_01360 1e-151
KEFEFEAG_01361 3.7e-51 S Iron-sulfur cluster assembly protein
KEFEFEAG_01362 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KEFEFEAG_01363 2.2e-154 P Belongs to the nlpA lipoprotein family
KEFEFEAG_01364 3.9e-12
KEFEFEAG_01365 4.8e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KEFEFEAG_01366 3.4e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KEFEFEAG_01367 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
KEFEFEAG_01368 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KEFEFEAG_01369 5.9e-22 S Protein of unknown function (DUF3042)
KEFEFEAG_01370 3.4e-67 yqhL P Rhodanese-like protein
KEFEFEAG_01371 5.6e-183 glk 2.7.1.2 G Glucokinase
KEFEFEAG_01372 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
KEFEFEAG_01373 1.4e-26 gluP 3.4.21.105 S Peptidase, S54 family
KEFEFEAG_01374 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
KEFEFEAG_01375 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KEFEFEAG_01376 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KEFEFEAG_01377 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KEFEFEAG_01378 0.0 S membrane
KEFEFEAG_01379 8.8e-71 yneR S Belongs to the HesB IscA family
KEFEFEAG_01380 2e-48 L PFAM transposase IS200-family protein
KEFEFEAG_01381 1.9e-161
KEFEFEAG_01382 2.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
KEFEFEAG_01383 2.8e-170 S AI-2E family transporter
KEFEFEAG_01384 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
KEFEFEAG_01385 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
KEFEFEAG_01386 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
KEFEFEAG_01387 4.8e-88 GM epimerase
KEFEFEAG_01388 1.7e-154 ypdB V (ABC) transporter
KEFEFEAG_01389 1.6e-241 yhdP S Transporter associated domain
KEFEFEAG_01390 2.9e-84 nrdI F Belongs to the NrdI family
KEFEFEAG_01391 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
KEFEFEAG_01392 2e-192 yeaN P Transporter, major facilitator family protein
KEFEFEAG_01393 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KEFEFEAG_01394 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KEFEFEAG_01395 5.5e-28
KEFEFEAG_01396 1.6e-48 S Glycosyltransferase, group 2 family protein
KEFEFEAG_01397 7.7e-31 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KEFEFEAG_01398 5.5e-29 M PFAM Glycosyl transferase family 2
KEFEFEAG_01399 4.2e-29 M Glycosyltransferase sugar-binding region containing DXD motif
KEFEFEAG_01400 1.7e-72 cps2I S Psort location CytoplasmicMembrane, score
KEFEFEAG_01403 3.2e-42 M Pfam:DUF1792
KEFEFEAG_01404 3.3e-66 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
KEFEFEAG_01405 2.4e-87 GT4 G Glycosyl transferase 4-like
KEFEFEAG_01406 8.9e-49 pglC M Bacterial sugar transferase
KEFEFEAG_01407 1e-107 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KEFEFEAG_01408 7.3e-101 epsB M biosynthesis protein
KEFEFEAG_01409 3.6e-161 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KEFEFEAG_01410 2e-40 K Transcriptional regulator, HxlR family
KEFEFEAG_01411 0.0 sbcC L Putative exonuclease SbcCD, C subunit
KEFEFEAG_01412 7.6e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KEFEFEAG_01413 1.7e-176 M Glycosyl hydrolases family 25
KEFEFEAG_01414 9.1e-144 ywqE 3.1.3.48 GM PHP domain protein
KEFEFEAG_01415 0.0 snf 2.7.11.1 KL domain protein
KEFEFEAG_01417 8.9e-37
KEFEFEAG_01418 1.9e-34 T Toxin-antitoxin system, toxin component, MazF family
KEFEFEAG_01419 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KEFEFEAG_01420 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KEFEFEAG_01421 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
KEFEFEAG_01422 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KEFEFEAG_01423 4.1e-275 lpdA 1.8.1.4 C Dehydrogenase
KEFEFEAG_01424 1.4e-47 yktA S Belongs to the UPF0223 family
KEFEFEAG_01425 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KEFEFEAG_01426 0.0 typA T GTP-binding protein TypA
KEFEFEAG_01427 2e-222 ftsW D Belongs to the SEDS family
KEFEFEAG_01428 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KEFEFEAG_01429 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KEFEFEAG_01430 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KEFEFEAG_01431 6.7e-198 ylbL T Belongs to the peptidase S16 family
KEFEFEAG_01433 9.1e-139 bamA GM domain, Protein
KEFEFEAG_01434 1.1e-62 S D5 N terminal like
KEFEFEAG_01435 1.1e-62 S D5 N terminal like
KEFEFEAG_01436 9.1e-139 bamA GM domain, Protein
KEFEFEAG_01437 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
KEFEFEAG_01438 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KEFEFEAG_01439 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
KEFEFEAG_01440 6.7e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KEFEFEAG_01441 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KEFEFEAG_01442 2.7e-39 ptsH G phosphocarrier protein HPR
KEFEFEAG_01443 2.9e-27
KEFEFEAG_01444 0.0 clpE O Belongs to the ClpA ClpB family
KEFEFEAG_01445 2.4e-99 S Pfam:DUF3816
KEFEFEAG_01446 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
KEFEFEAG_01447 6.7e-114
KEFEFEAG_01448 3.6e-157 V ABC transporter, ATP-binding protein
KEFEFEAG_01449 9.3e-65 gntR1 K Transcriptional regulator, GntR family
KEFEFEAG_01450 7.1e-248 yifK E Amino acid permease
KEFEFEAG_01451 2.6e-291 clcA P chloride
KEFEFEAG_01452 1.8e-34 secG U Preprotein translocase
KEFEFEAG_01453 6.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
KEFEFEAG_01454 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KEFEFEAG_01455 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KEFEFEAG_01456 6.3e-105 yxjI
KEFEFEAG_01457 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KEFEFEAG_01458 1.9e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KEFEFEAG_01459 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KEFEFEAG_01460 2.6e-86 K Acetyltransferase (GNAT) domain
KEFEFEAG_01461 4.4e-76 S PAS domain
KEFEFEAG_01462 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
KEFEFEAG_01463 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KEFEFEAG_01464 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
KEFEFEAG_01465 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KEFEFEAG_01466 1.1e-283 pipD E Dipeptidase
KEFEFEAG_01467 0.0 yfiC V ABC transporter
KEFEFEAG_01468 1.4e-309 lmrA V ABC transporter, ATP-binding protein
KEFEFEAG_01469 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEFEFEAG_01470 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KEFEFEAG_01471 0.0 yhcA V ABC transporter, ATP-binding protein
KEFEFEAG_01472 4.6e-38
KEFEFEAG_01473 3.5e-49 czrA K Transcriptional regulator, ArsR family
KEFEFEAG_01474 4.5e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KEFEFEAG_01475 5.1e-173 scrR K Transcriptional regulator, LacI family
KEFEFEAG_01476 3e-24
KEFEFEAG_01477 8.2e-103
KEFEFEAG_01478 8.4e-213 yttB EGP Major facilitator Superfamily
KEFEFEAG_01479 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KEFEFEAG_01480 2.2e-87
KEFEFEAG_01481 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
KEFEFEAG_01482 3.7e-165 tetP J Elongation factor G, domain IV
KEFEFEAG_01483 7.1e-29 L Transposase domain (DUF772)
KEFEFEAG_01490 7.1e-29 L Transposase domain (DUF772)
KEFEFEAG_01491 3.7e-165 tetP J Elongation factor G, domain IV
KEFEFEAG_01492 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEFEFEAG_01493 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KEFEFEAG_01494 1e-110 K Bacterial regulatory proteins, tetR family
KEFEFEAG_01495 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KEFEFEAG_01496 3.4e-77 ctsR K Belongs to the CtsR family
KEFEFEAG_01497 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
KEFEFEAG_01498 1.3e-16 S Hydrolases of the alpha beta superfamily
KEFEFEAG_01499 9e-130 S Hydrolases of the alpha beta superfamily
KEFEFEAG_01505 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KEFEFEAG_01506 1.5e-275 lysP E amino acid
KEFEFEAG_01507 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
KEFEFEAG_01508 2.7e-120 lssY 3.6.1.27 I phosphatase
KEFEFEAG_01509 6.7e-81 S Threonine/Serine exporter, ThrE
KEFEFEAG_01510 3.6e-129 thrE S Putative threonine/serine exporter
KEFEFEAG_01511 3.5e-31 cspC K Cold shock protein
KEFEFEAG_01512 1.1e-124 sirR K iron dependent repressor
KEFEFEAG_01513 2.6e-166 czcD P cation diffusion facilitator family transporter
KEFEFEAG_01514 5e-117 S membrane
KEFEFEAG_01515 7.6e-110 S VIT family
KEFEFEAG_01516 5.5e-83 usp1 T Belongs to the universal stress protein A family
KEFEFEAG_01517 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KEFEFEAG_01518 7.5e-152 glnH ET ABC transporter
KEFEFEAG_01519 4.2e-110 gluC P ABC transporter permease
KEFEFEAG_01520 1.4e-108 glnP P ABC transporter permease
KEFEFEAG_01521 7.3e-217 S CAAX protease self-immunity
KEFEFEAG_01522 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KEFEFEAG_01523 2.5e-53
KEFEFEAG_01524 4.9e-73 merR K MerR HTH family regulatory protein
KEFEFEAG_01525 2.7e-269 lmrB EGP Major facilitator Superfamily
KEFEFEAG_01526 9.5e-119 S Domain of unknown function (DUF4811)
KEFEFEAG_01527 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KEFEFEAG_01529 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KEFEFEAG_01530 2.6e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KEFEFEAG_01531 2.5e-186 I Alpha beta
KEFEFEAG_01532 8.5e-282 emrY EGP Major facilitator Superfamily
KEFEFEAG_01533 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
KEFEFEAG_01534 2e-250 yjjP S Putative threonine/serine exporter
KEFEFEAG_01535 1e-159 mleR K LysR family
KEFEFEAG_01536 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
KEFEFEAG_01537 4e-267 frdC 1.3.5.4 C FAD binding domain
KEFEFEAG_01538 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KEFEFEAG_01539 4.8e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KEFEFEAG_01540 1.9e-161 mleR K LysR family
KEFEFEAG_01541 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KEFEFEAG_01542 1.1e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
KEFEFEAG_01543 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
KEFEFEAG_01544 3.6e-168 L transposase, IS605 OrfB family
KEFEFEAG_01545 2.7e-263 S Uncharacterized protein conserved in bacteria (DUF2252)
KEFEFEAG_01546 1.5e-25
KEFEFEAG_01547 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KEFEFEAG_01548 3e-75
KEFEFEAG_01549 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KEFEFEAG_01550 3.9e-27 mleP3 S Membrane transport protein
KEFEFEAG_01551 3.6e-120 T Transcriptional regulatory protein, C terminal
KEFEFEAG_01552 9.9e-239 T GHKL domain
KEFEFEAG_01553 4.7e-109 S Peptidase propeptide and YPEB domain
KEFEFEAG_01554 6.4e-21 P nitric oxide dioxygenase activity
KEFEFEAG_01555 6e-10 P FAD-binding domain
KEFEFEAG_01556 4.3e-55 yphJ 4.1.1.44 S decarboxylase
KEFEFEAG_01557 5.3e-83 K Bacterial regulatory proteins, tetR family
KEFEFEAG_01558 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KEFEFEAG_01559 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
KEFEFEAG_01560 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
KEFEFEAG_01561 2.7e-85 C Flavodoxin
KEFEFEAG_01562 5.6e-158 K Transcriptional regulator
KEFEFEAG_01563 1.2e-30 lacA S transferase hexapeptide repeat
KEFEFEAG_01564 3.3e-137 sprD D Domain of Unknown Function (DUF1542)
KEFEFEAG_01565 3.1e-126 L PFAM Integrase catalytic region
KEFEFEAG_01566 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KEFEFEAG_01567 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KEFEFEAG_01568 2.6e-158 htpX O Belongs to the peptidase M48B family
KEFEFEAG_01569 7e-93 lemA S LemA family
KEFEFEAG_01570 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KEFEFEAG_01571 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
KEFEFEAG_01572 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KEFEFEAG_01573 1.8e-110 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KEFEFEAG_01574 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KEFEFEAG_01575 6.1e-216 patA 2.6.1.1 E Aminotransferase
KEFEFEAG_01576 5.8e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KEFEFEAG_01577 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KEFEFEAG_01578 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KEFEFEAG_01579 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KEFEFEAG_01580 1.1e-247 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KEFEFEAG_01581 2.5e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
KEFEFEAG_01582 1.9e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KEFEFEAG_01583 9.4e-17 UW LPXTG-motif cell wall anchor domain protein
KEFEFEAG_01584 6.6e-24 3.1.21.3 V Type I restriction modification DNA specificity domain
KEFEFEAG_01585 1.6e-219 hsdM 2.1.1.72 V type I restriction-modification system
KEFEFEAG_01586 3.1e-74 3.1.21.3 V type I restriction modification DNA specificity domain protein
KEFEFEAG_01588 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KEFEFEAG_01593 3.3e-17 K Transcriptional regulator
KEFEFEAG_01594 1.5e-132 dprA LU DNA protecting protein DprA
KEFEFEAG_01595 1.2e-43 L Belongs to the 'phage' integrase family
KEFEFEAG_01600 6.3e-39 S hydrolase activity
KEFEFEAG_01602 4.7e-41
KEFEFEAG_01604 6.5e-08 K Cro/C1-type HTH DNA-binding domain
KEFEFEAG_01605 4.2e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KEFEFEAG_01606 6.7e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KEFEFEAG_01607 9.6e-115 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
KEFEFEAG_01608 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KEFEFEAG_01609 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KEFEFEAG_01610 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KEFEFEAG_01611 5.1e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KEFEFEAG_01612 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KEFEFEAG_01613 7.4e-134 K LysR substrate binding domain
KEFEFEAG_01614 0.0 S SEC-C Motif Domain Protein
KEFEFEAG_01615 5.2e-50
KEFEFEAG_01616 2.1e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KEFEFEAG_01617 6.3e-19 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KEFEFEAG_01618 1.2e-115 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KEFEFEAG_01619 5.1e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KEFEFEAG_01620 1.8e-226 clcA_2 P Chloride transporter, ClC family
KEFEFEAG_01621 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KEFEFEAG_01622 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
KEFEFEAG_01624 1.9e-262 dtpT U amino acid peptide transporter
KEFEFEAG_01625 1.4e-158 yjjH S Calcineurin-like phosphoesterase
KEFEFEAG_01628 7.6e-151 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
KEFEFEAG_01629 5.5e-110
KEFEFEAG_01630 2.8e-252 EGP Major facilitator Superfamily
KEFEFEAG_01631 9.5e-300 aspT P Predicted Permease Membrane Region
KEFEFEAG_01632 6.9e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KEFEFEAG_01633 2.6e-180 comGA NU Type II IV secretion system protein
KEFEFEAG_01634 9.5e-181 comGB NU type II secretion system
KEFEFEAG_01635 7.1e-47 comGC U competence protein ComGC
KEFEFEAG_01636 8.3e-78 NU general secretion pathway protein
KEFEFEAG_01637 2.7e-40
KEFEFEAG_01638 6.3e-70
KEFEFEAG_01640 4.2e-144 ytxK 2.1.1.72 L N-6 DNA Methylase
KEFEFEAG_01641 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KEFEFEAG_01642 2.2e-113 S Calcineurin-like phosphoesterase
KEFEFEAG_01643 5.1e-93 yutD S Protein of unknown function (DUF1027)
KEFEFEAG_01644 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KEFEFEAG_01645 2.4e-105 S Protein of unknown function (DUF1461)
KEFEFEAG_01646 5.5e-110 dedA S SNARE-like domain protein
KEFEFEAG_01647 3.6e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
KEFEFEAG_01648 2.3e-209 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
KEFEFEAG_01649 1.4e-75 M transferase activity, transferring glycosyl groups
KEFEFEAG_01650 7.7e-89 cps3F
KEFEFEAG_01651 3.9e-28 M biosynthesis protein
KEFEFEAG_01652 2e-76 rgpB GT2 M Glycosyl transferase family 2
KEFEFEAG_01653 3.4e-66 S Glycosyltransferase like family
KEFEFEAG_01654 3.7e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
KEFEFEAG_01655 1.1e-54 S Acyltransferase family
KEFEFEAG_01656 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
KEFEFEAG_01657 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
KEFEFEAG_01658 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KEFEFEAG_01659 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KEFEFEAG_01660 3.5e-163 S Tetratricopeptide repeat
KEFEFEAG_01661 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KEFEFEAG_01662 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KEFEFEAG_01663 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KEFEFEAG_01664 1.4e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
KEFEFEAG_01665 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
KEFEFEAG_01666 1.3e-08
KEFEFEAG_01667 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KEFEFEAG_01668 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KEFEFEAG_01669 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KEFEFEAG_01670 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KEFEFEAG_01671 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KEFEFEAG_01672 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KEFEFEAG_01673 2.1e-87
KEFEFEAG_01674 3.9e-132 L Belongs to the 'phage' integrase family
KEFEFEAG_01675 8.3e-09 K Transcriptional regulator
KEFEFEAG_01676 1.4e-18 S Helix-turn-helix domain
KEFEFEAG_01677 2.3e-49 S Phage regulatory protein Rha (Phage_pRha)
KEFEFEAG_01679 1.7e-08
KEFEFEAG_01682 2.6e-08 L DnaD domain protein
KEFEFEAG_01684 9.1e-71
KEFEFEAG_01686 1e-277 V Type II restriction enzyme, methylase subunits
KEFEFEAG_01689 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KEFEFEAG_01690 5.2e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KEFEFEAG_01691 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KEFEFEAG_01692 1.3e-35 ynzC S UPF0291 protein
KEFEFEAG_01693 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
KEFEFEAG_01694 4.6e-117 plsC 2.3.1.51 I Acyltransferase
KEFEFEAG_01695 3.2e-141 yabB 2.1.1.223 L Methyltransferase small domain
KEFEFEAG_01696 5.4e-49 yazA L GIY-YIG catalytic domain protein
KEFEFEAG_01697 4.4e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEFEFEAG_01698 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
KEFEFEAG_01699 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KEFEFEAG_01700 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KEFEFEAG_01701 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KEFEFEAG_01702 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KEFEFEAG_01703 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
KEFEFEAG_01704 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KEFEFEAG_01705 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KEFEFEAG_01706 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KEFEFEAG_01707 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
KEFEFEAG_01708 1e-215 nusA K Participates in both transcription termination and antitermination
KEFEFEAG_01709 1e-44 ylxR K Protein of unknown function (DUF448)
KEFEFEAG_01710 4.5e-49 ylxQ J ribosomal protein
KEFEFEAG_01711 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KEFEFEAG_01712 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KEFEFEAG_01713 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KEFEFEAG_01714 1.3e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KEFEFEAG_01715 5.3e-283 2.4.1.5 GH13 G Glycosyl hydrolase family 70
KEFEFEAG_01716 5.8e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KEFEFEAG_01717 3.4e-250 mmuP E amino acid
KEFEFEAG_01719 1.8e-44 csd1 3.5.1.28 G domain, Protein
KEFEFEAG_01720 0.0 ganB 3.2.1.89 G arabinogalactan
KEFEFEAG_01721 1.5e-23 S Acyltransferase family
KEFEFEAG_01723 3.8e-190 V Beta-lactamase
KEFEFEAG_01724 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KEFEFEAG_01725 5e-122 yhiD S MgtC family
KEFEFEAG_01726 6.4e-39 S GyrI-like small molecule binding domain
KEFEFEAG_01727 2.7e-70 S GyrI-like small molecule binding domain
KEFEFEAG_01729 5.5e-118 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KEFEFEAG_01730 6e-49 azlD E Branched-chain amino acid transport
KEFEFEAG_01731 1.4e-119 azlC E azaleucine resistance protein AzlC
KEFEFEAG_01732 2.1e-260 K Aminotransferase class I and II
KEFEFEAG_01733 3.6e-288 S amidohydrolase
KEFEFEAG_01734 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KEFEFEAG_01735 1.9e-155 tatD L hydrolase, TatD family
KEFEFEAG_01736 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KEFEFEAG_01737 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KEFEFEAG_01738 6.8e-37 veg S Biofilm formation stimulator VEG
KEFEFEAG_01739 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KEFEFEAG_01740 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
KEFEFEAG_01741 1.4e-121 fhuC P ABC transporter
KEFEFEAG_01742 2.4e-115 znuB U ABC 3 transport family
KEFEFEAG_01743 3.4e-212 bacI V MacB-like periplasmic core domain
KEFEFEAG_01744 4.4e-129 V ABC transporter
KEFEFEAG_01745 5.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KEFEFEAG_01746 5.2e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KEFEFEAG_01747 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KEFEFEAG_01748 3e-147 E Glyoxalase-like domain
KEFEFEAG_01749 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
KEFEFEAG_01750 2.9e-96 S reductase
KEFEFEAG_01751 1.4e-57 KT Putative sugar diacid recognition
KEFEFEAG_01752 1.7e-219 EG GntP family permease
KEFEFEAG_01753 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KEFEFEAG_01754 7.7e-58
KEFEFEAG_01756 1.2e-133 mltD CBM50 M NlpC P60 family protein
KEFEFEAG_01757 5.7e-29
KEFEFEAG_01758 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
KEFEFEAG_01759 9.8e-32 ykzG S Belongs to the UPF0356 family
KEFEFEAG_01760 2.4e-78
KEFEFEAG_01761 7.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
KEFEFEAG_01762 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KEFEFEAG_01763 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
KEFEFEAG_01764 4e-113 yjbH Q Thioredoxin
KEFEFEAG_01765 9.2e-264 pipD E Dipeptidase
KEFEFEAG_01766 3e-203 coiA 3.6.4.12 S Competence protein
KEFEFEAG_01767 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KEFEFEAG_01768 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KEFEFEAG_01769 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KEFEFEAG_01770 1.4e-130 hrtB V ABC transporter permease
KEFEFEAG_01771 2.6e-86 ygfC K transcriptional regulator (TetR family)
KEFEFEAG_01772 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
KEFEFEAG_01773 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
KEFEFEAG_01774 3e-34
KEFEFEAG_01775 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KEFEFEAG_01776 1.5e-132 K Transcriptional regulatory protein, C-terminal domain protein
KEFEFEAG_01777 8.6e-159 pstS P Phosphate
KEFEFEAG_01778 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
KEFEFEAG_01779 4.7e-152 pstA P Phosphate transport system permease protein PstA
KEFEFEAG_01780 8.9e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KEFEFEAG_01781 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
KEFEFEAG_01782 2.7e-144
KEFEFEAG_01783 4.4e-118 ydaM M Glycosyl transferase
KEFEFEAG_01784 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KEFEFEAG_01786 2.6e-177 S Aldo keto reductase
KEFEFEAG_01787 9.9e-75 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
KEFEFEAG_01788 0.0 L Helicase C-terminal domain protein
KEFEFEAG_01790 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KEFEFEAG_01791 1.2e-10 S Protein of unknown function (DUF4044)
KEFEFEAG_01792 7.3e-56
KEFEFEAG_01793 3.1e-77 mraZ K Belongs to the MraZ family
KEFEFEAG_01794 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KEFEFEAG_01795 2.6e-56 ftsL D Cell division protein FtsL
KEFEFEAG_01796 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KEFEFEAG_01797 2.9e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KEFEFEAG_01798 2.9e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KEFEFEAG_01799 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KEFEFEAG_01800 1.9e-147 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KEFEFEAG_01801 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KEFEFEAG_01802 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KEFEFEAG_01803 1.6e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KEFEFEAG_01804 3.2e-40 yggT S YGGT family
KEFEFEAG_01805 5.1e-142 ylmH S S4 domain protein
KEFEFEAG_01806 1.9e-42 divIVA D DivIVA domain protein
KEFEFEAG_01807 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KEFEFEAG_01808 4.2e-32 cspA K Cold shock protein
KEFEFEAG_01809 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KEFEFEAG_01811 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KEFEFEAG_01812 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
KEFEFEAG_01813 1.3e-57 XK27_04120 S Putative amino acid metabolism
KEFEFEAG_01814 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KEFEFEAG_01815 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
KEFEFEAG_01816 9e-119 S Repeat protein
KEFEFEAG_01817 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KEFEFEAG_01818 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KEFEFEAG_01820 4.4e-100 L Helix-turn-helix domain
KEFEFEAG_01821 4.5e-160 L hmm pf00665
KEFEFEAG_01822 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KEFEFEAG_01823 1.2e-264 glnP P ABC transporter
KEFEFEAG_01824 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KEFEFEAG_01826 7.2e-221 cycA E Amino acid permease
KEFEFEAG_01827 3.3e-217 nupG F Nucleoside transporter
KEFEFEAG_01828 5.6e-169 rihC 3.2.2.1 F Nucleoside
KEFEFEAG_01829 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
KEFEFEAG_01830 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KEFEFEAG_01831 4.3e-151 noc K Belongs to the ParB family
KEFEFEAG_01832 3.9e-139 soj D Sporulation initiation inhibitor
KEFEFEAG_01833 1.7e-154 spo0J K Belongs to the ParB family
KEFEFEAG_01834 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
KEFEFEAG_01835 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KEFEFEAG_01836 1.5e-135 XK27_01040 S Protein of unknown function (DUF1129)
KEFEFEAG_01837 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KEFEFEAG_01838 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KEFEFEAG_01839 9.3e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
KEFEFEAG_01840 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KEFEFEAG_01841 9.5e-172 deoR K sugar-binding domain protein
KEFEFEAG_01842 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KEFEFEAG_01843 1.2e-123 K response regulator
KEFEFEAG_01844 6.5e-199 hpk31 2.7.13.3 T Histidine kinase
KEFEFEAG_01845 2.4e-135 azlC E AzlC protein
KEFEFEAG_01846 2.1e-52 azlD S branched-chain amino acid
KEFEFEAG_01848 0.0 L PLD-like domain
KEFEFEAG_01849 3.4e-33 higA K addiction module antidote protein HigA
KEFEFEAG_01850 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KEFEFEAG_01851 1.1e-45 hsdS 2.1.1.72, 3.1.21.3 V DNA specificity domain
KEFEFEAG_01852 1.4e-25 bcgIA 2.1.1.72 V Type I restriction-modification system methyltransferase subunit()
KEFEFEAG_01853 1.9e-07
KEFEFEAG_01856 2.6e-41 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
KEFEFEAG_01857 6.4e-33
KEFEFEAG_01858 1.4e-51
KEFEFEAG_01859 1.1e-113 frnE Q DSBA-like thioredoxin domain
KEFEFEAG_01860 1.7e-78 I alpha/beta hydrolase fold
KEFEFEAG_01861 8.5e-20 K Helix-turn-helix XRE-family like proteins
KEFEFEAG_01862 1.1e-35 S Phage derived protein Gp49-like (DUF891)
KEFEFEAG_01864 1.6e-45 yrvD S Pfam:DUF1049
KEFEFEAG_01865 9.5e-155 3.1.3.102, 3.1.3.104 S hydrolase
KEFEFEAG_01866 8.1e-90 ntd 2.4.2.6 F Nucleoside
KEFEFEAG_01867 1.3e-20
KEFEFEAG_01868 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
KEFEFEAG_01869 6.1e-54 yviA S Protein of unknown function (DUF421)
KEFEFEAG_01870 1.3e-125 G Peptidase_C39 like family
KEFEFEAG_01871 2.1e-25
KEFEFEAG_01873 0.0 ganB 3.2.1.89 G arabinogalactan
KEFEFEAG_01874 0.0 clpL O associated with various cellular activities
KEFEFEAG_01875 7.8e-32
KEFEFEAG_01876 6.1e-216 patA 2.6.1.1 E Aminotransferase
KEFEFEAG_01877 8e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KEFEFEAG_01878 1.9e-71 osmC O OsmC-like protein
KEFEFEAG_01879 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KEFEFEAG_01880 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KEFEFEAG_01881 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
KEFEFEAG_01882 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KEFEFEAG_01884 4.1e-115 S Membrane
KEFEFEAG_01885 6.8e-09 O Zinc-dependent metalloprotease
KEFEFEAG_01886 2.3e-105 O Zinc-dependent metalloprotease
KEFEFEAG_01887 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KEFEFEAG_01888 8e-157 metQ_4 P Belongs to the nlpA lipoprotein family
KEFEFEAG_01890 1.4e-122 L hmm pf00665
KEFEFEAG_01891 3.5e-186 L Transposase
KEFEFEAG_01892 5.1e-139 L Bacterial dnaA protein
KEFEFEAG_01893 5.1e-122 L Integrase core domain
KEFEFEAG_01894 2.4e-174 L PFAM Integrase, catalytic core
KEFEFEAG_01895 3e-80 L Bacterial dnaA protein
KEFEFEAG_01896 2e-100 L Integrase core domain
KEFEFEAG_01897 3e-13
KEFEFEAG_01898 3.4e-47
KEFEFEAG_01899 4.4e-140 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KEFEFEAG_01900 5.5e-153 EG EamA-like transporter family
KEFEFEAG_01901 9.4e-118 L Integrase
KEFEFEAG_01902 1.2e-157 rssA S Phospholipase, patatin family
KEFEFEAG_01903 3.2e-232 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
KEFEFEAG_01904 1e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KEFEFEAG_01905 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KEFEFEAG_01906 4.4e-35 yozE S Belongs to the UPF0346 family
KEFEFEAG_01907 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
KEFEFEAG_01908 9.5e-172 ypmR E lipolytic protein G-D-S-L family
KEFEFEAG_01909 1.7e-151 DegV S EDD domain protein, DegV family
KEFEFEAG_01910 3.4e-112 hlyIII S protein, hemolysin III
KEFEFEAG_01911 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KEFEFEAG_01912 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KEFEFEAG_01913 0.0 yfmR S ABC transporter, ATP-binding protein
KEFEFEAG_01914 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KEFEFEAG_01915 1.5e-236 S Tetratricopeptide repeat protein
KEFEFEAG_01916 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KEFEFEAG_01917 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KEFEFEAG_01918 5.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
KEFEFEAG_01919 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KEFEFEAG_01920 8.5e-14 M Lysin motif
KEFEFEAG_01921 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
KEFEFEAG_01922 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
KEFEFEAG_01923 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KEFEFEAG_01924 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KEFEFEAG_01925 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KEFEFEAG_01926 2.2e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KEFEFEAG_01927 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KEFEFEAG_01928 2.7e-163 xerD D recombinase XerD
KEFEFEAG_01929 2.3e-167 cvfB S S1 domain
KEFEFEAG_01930 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KEFEFEAG_01931 0.0 dnaE 2.7.7.7 L DNA polymerase
KEFEFEAG_01932 3.1e-30 S Protein of unknown function (DUF2929)
KEFEFEAG_01933 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KEFEFEAG_01934 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KEFEFEAG_01935 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
KEFEFEAG_01936 1.2e-219 patA 2.6.1.1 E Aminotransferase
KEFEFEAG_01937 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KEFEFEAG_01938 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KEFEFEAG_01939 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KEFEFEAG_01940 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KEFEFEAG_01941 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
KEFEFEAG_01942 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KEFEFEAG_01943 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KEFEFEAG_01944 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KEFEFEAG_01945 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
KEFEFEAG_01946 4.6e-177 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KEFEFEAG_01947 5.2e-88 bioY S BioY family
KEFEFEAG_01948 3.9e-262 argH 4.3.2.1 E argininosuccinate lyase
KEFEFEAG_01949 2.2e-156 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KEFEFEAG_01950 2.7e-39 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KEFEFEAG_01951 1.5e-183 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KEFEFEAG_01952 7.3e-49 lacA S transferase hexapeptide repeat
KEFEFEAG_01953 9.4e-32 S thiolester hydrolase activity
KEFEFEAG_01954 2e-152 S Alpha beta hydrolase
KEFEFEAG_01955 3.3e-92 padC Q Phenolic acid decarboxylase
KEFEFEAG_01956 3.6e-88 padR K Virulence activator alpha C-term
KEFEFEAG_01957 4.7e-66 GM NAD(P)H-binding
KEFEFEAG_01958 2.3e-155 ypuA S Protein of unknown function (DUF1002)
KEFEFEAG_01959 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
KEFEFEAG_01960 2.2e-202 ykiI
KEFEFEAG_01961 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KEFEFEAG_01962 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KEFEFEAG_01963 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KEFEFEAG_01964 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KEFEFEAG_01965 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KEFEFEAG_01966 3.4e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KEFEFEAG_01967 4.2e-130 IQ reductase
KEFEFEAG_01968 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KEFEFEAG_01969 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KEFEFEAG_01970 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KEFEFEAG_01971 4.2e-77 marR K Transcriptional regulator, MarR family
KEFEFEAG_01972 1.6e-18 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KEFEFEAG_01973 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KEFEFEAG_01974 9.4e-159 amtB P ammonium transporter
KEFEFEAG_01975 3e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
KEFEFEAG_01976 1.8e-90 S B3 4 domain
KEFEFEAG_01977 1.1e-90
KEFEFEAG_01978 1.3e-70 pnb C nitroreductase
KEFEFEAG_01980 3.7e-91 yqiG C Oxidoreductase
KEFEFEAG_01981 7.8e-20 yqiG C Oxidoreductase
KEFEFEAG_01982 1.1e-50 yqiG C Oxidoreductase
KEFEFEAG_01983 8.5e-54 S macrophage migration inhibitory factor
KEFEFEAG_01984 2.4e-65 K HxlR-like helix-turn-helix
KEFEFEAG_01985 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KEFEFEAG_01987 1.9e-225 L Transposase IS66 family
KEFEFEAG_01991 6.1e-57
KEFEFEAG_01992 1.7e-102 K Transcriptional regulator C-terminal region
KEFEFEAG_01993 2.1e-74 S membrane
KEFEFEAG_01994 6.1e-88 S membrane
KEFEFEAG_01995 1.2e-112 GM NAD(P)H-binding
KEFEFEAG_01996 1.1e-64 yneR
KEFEFEAG_01997 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
KEFEFEAG_01998 3.7e-140 T EAL domain
KEFEFEAG_02003 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KEFEFEAG_02004 2.7e-95 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KEFEFEAG_02005 1e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KEFEFEAG_02006 3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KEFEFEAG_02007 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KEFEFEAG_02008 2.2e-49 ebh D nuclear chromosome segregation
KEFEFEAG_02010 5.9e-55 UW LPXTG-motif cell wall anchor domain protein
KEFEFEAG_02011 6.4e-241 E amino acid
KEFEFEAG_02012 2.1e-147 yxiO S Vacuole effluxer Atg22 like
KEFEFEAG_02014 2.1e-29
KEFEFEAG_02015 1.9e-101 K DNA-templated transcription, initiation
KEFEFEAG_02016 2.4e-34
KEFEFEAG_02017 6.7e-87
KEFEFEAG_02018 1.5e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KEFEFEAG_02019 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KEFEFEAG_02020 0.0 yjbQ P TrkA C-terminal domain protein
KEFEFEAG_02021 6.7e-278 pipD E Dipeptidase
KEFEFEAG_02022 1.2e-07 UW Hep Hag repeat protein
KEFEFEAG_02023 1e-16 sraP UW this gene contains a nucleotide ambiguity which may be the result of a sequencing error
KEFEFEAG_02025 4.6e-196 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KEFEFEAG_02026 1.1e-225 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KEFEFEAG_02027 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KEFEFEAG_02028 1.3e-154 asp3 S Accessory Sec secretory system ASP3
KEFEFEAG_02029 5.3e-217 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
KEFEFEAG_02030 2.6e-195 M transferase activity, transferring glycosyl groups
KEFEFEAG_02031 2.2e-144 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
KEFEFEAG_02032 2.6e-191 nss M transferase activity, transferring glycosyl groups
KEFEFEAG_02033 1.8e-11 sraP UW domain, Protein
KEFEFEAG_02035 0.0 M LPXTG-motif cell wall anchor domain protein
KEFEFEAG_02036 7.5e-181 M LPXTG-motif cell wall anchor domain protein
KEFEFEAG_02037 0.0 trxB2 1.8.1.9 C Thioredoxin domain
KEFEFEAG_02038 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
KEFEFEAG_02039 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KEFEFEAG_02040 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KEFEFEAG_02043 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KEFEFEAG_02044 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
KEFEFEAG_02045 2.4e-223 mdtG EGP Major facilitator Superfamily
KEFEFEAG_02046 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KEFEFEAG_02047 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KEFEFEAG_02048 5.1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)