ORF_ID e_value Gene_name EC_number CAZy COGs Description
APOGKADJ_00001 1.7e-156 L hmm pf00665
APOGKADJ_00002 9.3e-127 L Helix-turn-helix domain
APOGKADJ_00003 1.9e-56 cadX K Bacterial regulatory protein, arsR family
APOGKADJ_00004 5.2e-91 cadD P Cadmium resistance transporter
APOGKADJ_00005 7.2e-192 L Transposase
APOGKADJ_00006 1.7e-08 S Protein of unknown function, DUF536
APOGKADJ_00007 5.2e-21
APOGKADJ_00008 2.7e-24
APOGKADJ_00009 1e-73
APOGKADJ_00010 6.6e-09 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APOGKADJ_00012 3.1e-237 L Transposase
APOGKADJ_00013 5.6e-261 S Uncharacterised protein family (UPF0236)
APOGKADJ_00014 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APOGKADJ_00015 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
APOGKADJ_00016 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APOGKADJ_00017 7.4e-141 ymfM S Helix-turn-helix domain
APOGKADJ_00018 3.2e-250 ymfH S Peptidase M16
APOGKADJ_00019 1.6e-230 ymfF S Peptidase M16 inactive domain protein
APOGKADJ_00020 2.6e-160 aatB ET ABC transporter substrate-binding protein
APOGKADJ_00021 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APOGKADJ_00022 3.2e-102 glnP P ABC transporter permease
APOGKADJ_00023 1.2e-91 mreD M rod shape-determining protein MreD
APOGKADJ_00024 2.2e-151 mreC M Involved in formation and maintenance of cell shape
APOGKADJ_00025 1.7e-179 mreB D cell shape determining protein MreB
APOGKADJ_00026 6.8e-121 radC L DNA repair protein
APOGKADJ_00027 3.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
APOGKADJ_00028 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
APOGKADJ_00029 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
APOGKADJ_00030 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
APOGKADJ_00031 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
APOGKADJ_00032 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
APOGKADJ_00033 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APOGKADJ_00034 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APOGKADJ_00035 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
APOGKADJ_00036 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APOGKADJ_00037 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APOGKADJ_00038 1.3e-262 L Transposase
APOGKADJ_00039 1.1e-229 pbuG S permease
APOGKADJ_00040 8.6e-127 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
APOGKADJ_00041 8.4e-111 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
APOGKADJ_00042 1.7e-136 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
APOGKADJ_00043 3.7e-168 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
APOGKADJ_00044 2.5e-135 S Belongs to the UPF0246 family
APOGKADJ_00045 2.5e-138 S Membrane
APOGKADJ_00046 1.4e-74 4.4.1.5 E Glyoxalase
APOGKADJ_00047 1.5e-21
APOGKADJ_00048 7.1e-86 yueI S Protein of unknown function (DUF1694)
APOGKADJ_00049 1.7e-235 rarA L recombination factor protein RarA
APOGKADJ_00050 4.4e-46
APOGKADJ_00051 4.3e-83 usp6 T universal stress protein
APOGKADJ_00052 2.8e-207 araR K Transcriptional regulator
APOGKADJ_00053 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
APOGKADJ_00054 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
APOGKADJ_00055 1.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
APOGKADJ_00056 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
APOGKADJ_00057 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
APOGKADJ_00058 2.6e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APOGKADJ_00059 7.2e-96 L Helix-turn-helix domain
APOGKADJ_00060 9.6e-139 L hmm pf00665
APOGKADJ_00061 1.9e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
APOGKADJ_00062 1.3e-240 L PFAM Integrase catalytic region
APOGKADJ_00063 8.7e-182 L COG2826 Transposase and inactivated derivatives, IS30 family
APOGKADJ_00064 1.8e-223 L Transposase IS66 family
APOGKADJ_00065 4.7e-170 cobD 4.1.1.81 E Aminotransferase class I and II
APOGKADJ_00067 7.6e-31 L Phage-associated protein
APOGKADJ_00068 4.1e-11 S head-tail joining protein
APOGKADJ_00069 1.6e-67 yqkB S Belongs to the HesB IscA family
APOGKADJ_00070 2.7e-49
APOGKADJ_00071 2.8e-132 M transferase activity, transferring glycosyl groups
APOGKADJ_00072 8.8e-150 waaB GT4 M Glycosyl transferases group 1
APOGKADJ_00073 8.1e-239 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
APOGKADJ_00074 5.8e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
APOGKADJ_00075 3.2e-118 rfbP 2.7.8.6 M Bacterial sugar transferase
APOGKADJ_00076 2.7e-174 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
APOGKADJ_00077 3.3e-146 cps1D M Domain of unknown function (DUF4422)
APOGKADJ_00078 7.4e-125 recX 2.4.1.337 GT4 S Regulatory protein RecX
APOGKADJ_00079 4.9e-31
APOGKADJ_00080 6.6e-34 S Protein of unknown function (DUF2922)
APOGKADJ_00081 3.2e-153 yihY S Belongs to the UPF0761 family
APOGKADJ_00082 1.1e-281 yjeM E Amino Acid
APOGKADJ_00083 4e-254 E Arginine ornithine antiporter
APOGKADJ_00084 1.7e-220 arcT 2.6.1.1 E Aminotransferase
APOGKADJ_00085 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
APOGKADJ_00086 1.5e-77 fld C Flavodoxin
APOGKADJ_00087 2.3e-67 gtcA S Teichoic acid glycosylation protein
APOGKADJ_00088 9.3e-56
APOGKADJ_00089 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APOGKADJ_00091 6.9e-229 yfmL L DEAD DEAH box helicase
APOGKADJ_00092 4.5e-191 mocA S Oxidoreductase
APOGKADJ_00093 9.1e-62 S Domain of unknown function (DUF4828)
APOGKADJ_00094 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
APOGKADJ_00095 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
APOGKADJ_00096 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
APOGKADJ_00097 7.2e-197 S Protein of unknown function (DUF3114)
APOGKADJ_00098 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
APOGKADJ_00099 1.1e-119 ybhL S Belongs to the BI1 family
APOGKADJ_00100 3.1e-21
APOGKADJ_00101 5.9e-91 K Acetyltransferase (GNAT) family
APOGKADJ_00102 6.4e-78 K LytTr DNA-binding domain
APOGKADJ_00103 7.3e-69 S Protein of unknown function (DUF3021)
APOGKADJ_00104 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
APOGKADJ_00105 8.5e-172 XK27_00915 C Luciferase-like monooxygenase
APOGKADJ_00106 2e-74 ogt 2.1.1.63 L Methyltransferase
APOGKADJ_00107 4.8e-122 pnb C nitroreductase
APOGKADJ_00108 2.1e-91
APOGKADJ_00109 1.4e-90 S B3 4 domain
APOGKADJ_00110 2.1e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
APOGKADJ_00111 7.9e-158 amtB P ammonium transporter
APOGKADJ_00112 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
APOGKADJ_00114 1.3e-46
APOGKADJ_00115 3.2e-96 S PFAM Archaeal ATPase
APOGKADJ_00116 9.1e-132 L PFAM Integrase catalytic region
APOGKADJ_00117 4.2e-111 3.6.1.13, 3.6.1.55 F NUDIX domain
APOGKADJ_00118 4e-230 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APOGKADJ_00119 5.6e-79 pncA Q Isochorismatase family
APOGKADJ_00120 7.9e-61 pldB 3.1.1.5 I Serine aminopeptidase, S33
APOGKADJ_00122 2.7e-26 K TRANSCRIPTIONal
APOGKADJ_00123 3e-23
APOGKADJ_00124 6.5e-31 S Plasmid replication protein
APOGKADJ_00126 3.6e-75 G Peptidase_C39 like family
APOGKADJ_00128 3e-54 pduU E BMC
APOGKADJ_00129 2.2e-75 glf 5.4.99.9 M UDP-galactopyranose mutase
APOGKADJ_00130 1.3e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
APOGKADJ_00131 1.5e-86
APOGKADJ_00132 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
APOGKADJ_00133 2.6e-214 yttB EGP Major facilitator Superfamily
APOGKADJ_00134 8.2e-103
APOGKADJ_00135 3e-24
APOGKADJ_00136 5.1e-173 scrR K Transcriptional regulator, LacI family
APOGKADJ_00137 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APOGKADJ_00138 3.5e-49 czrA K Transcriptional regulator, ArsR family
APOGKADJ_00139 4.6e-38
APOGKADJ_00140 0.0 yhcA V ABC transporter, ATP-binding protein
APOGKADJ_00141 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
APOGKADJ_00142 4e-132 hrtB V ABC transporter permease
APOGKADJ_00143 2.6e-86 ygfC K transcriptional regulator (TetR family)
APOGKADJ_00144 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
APOGKADJ_00145 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
APOGKADJ_00146 3e-34
APOGKADJ_00147 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APOGKADJ_00149 3.1e-226 yxiO S Vacuole effluxer Atg22 like
APOGKADJ_00150 1.8e-214 npp S type I phosphodiesterase nucleotide pyrophosphatase
APOGKADJ_00151 1.4e-240 E amino acid
APOGKADJ_00152 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APOGKADJ_00154 6.7e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
APOGKADJ_00155 7.8e-41 S Cytochrome B5
APOGKADJ_00156 5.4e-09 S Cytochrome B5
APOGKADJ_00157 1.8e-39 S Cytochrome B5
APOGKADJ_00158 1.7e-70 elaA S Gnat family
APOGKADJ_00159 3e-119 GM NmrA-like family
APOGKADJ_00160 2.5e-52 hxlR K Transcriptional regulator, HxlR family
APOGKADJ_00161 3.7e-108 XK27_02070 S Nitroreductase family
APOGKADJ_00162 3.5e-79 K Transcriptional regulator, HxlR family
APOGKADJ_00163 2.4e-229
APOGKADJ_00164 6.5e-210 EGP Major facilitator Superfamily
APOGKADJ_00165 9.8e-255 pepC 3.4.22.40 E aminopeptidase
APOGKADJ_00166 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
APOGKADJ_00167 0.0 pepN 3.4.11.2 E aminopeptidase
APOGKADJ_00168 2e-92 folT S ECF transporter, substrate-specific component
APOGKADJ_00169 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
APOGKADJ_00170 3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
APOGKADJ_00171 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
APOGKADJ_00172 2.8e-202 2.7.7.65 T GGDEF domain
APOGKADJ_00173 2.8e-59 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
APOGKADJ_00176 2.2e-22
APOGKADJ_00178 3.7e-16 K Transcriptional regulator, HxlR family
APOGKADJ_00179 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
APOGKADJ_00180 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APOGKADJ_00181 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APOGKADJ_00182 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APOGKADJ_00183 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APOGKADJ_00184 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
APOGKADJ_00185 2.8e-31 yajC U Preprotein translocase
APOGKADJ_00186 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
APOGKADJ_00187 2.4e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APOGKADJ_00188 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APOGKADJ_00189 4.1e-43 yrzL S Belongs to the UPF0297 family
APOGKADJ_00190 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APOGKADJ_00191 6.1e-48 yrzB S Belongs to the UPF0473 family
APOGKADJ_00192 1e-85 cvpA S Colicin V production protein
APOGKADJ_00193 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APOGKADJ_00194 6.1e-54 trxA O Belongs to the thioredoxin family
APOGKADJ_00195 1.3e-96 yslB S Protein of unknown function (DUF2507)
APOGKADJ_00196 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
APOGKADJ_00197 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APOGKADJ_00198 4.4e-94 S Phosphoesterase
APOGKADJ_00199 3.6e-76 ykuL S (CBS) domain
APOGKADJ_00200 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
APOGKADJ_00201 3.4e-147 ykuT M mechanosensitive ion channel
APOGKADJ_00202 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APOGKADJ_00203 3.5e-26
APOGKADJ_00204 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
APOGKADJ_00205 1.9e-181 ccpA K catabolite control protein A
APOGKADJ_00206 1.9e-134
APOGKADJ_00207 3.5e-132 yebC K Transcriptional regulatory protein
APOGKADJ_00208 2.6e-180 comGA NU Type II IV secretion system protein
APOGKADJ_00209 9.5e-181 comGB NU type II secretion system
APOGKADJ_00210 7.1e-47 comGC U competence protein ComGC
APOGKADJ_00211 8.3e-78 NU general secretion pathway protein
APOGKADJ_00212 2.7e-40
APOGKADJ_00213 6.3e-70
APOGKADJ_00215 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
APOGKADJ_00216 1.3e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APOGKADJ_00217 2.2e-113 S Calcineurin-like phosphoesterase
APOGKADJ_00218 1.3e-93 yutD S Protein of unknown function (DUF1027)
APOGKADJ_00219 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APOGKADJ_00220 2.4e-105 S Protein of unknown function (DUF1461)
APOGKADJ_00221 5.5e-110 dedA S SNARE-like domain protein
APOGKADJ_00222 3.3e-39 arbZ I Phosphate acyltransferases
APOGKADJ_00223 4.4e-33 V ABC transporter
APOGKADJ_00226 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APOGKADJ_00227 6.8e-65 K HxlR-like helix-turn-helix
APOGKADJ_00228 8.5e-54 S macrophage migration inhibitory factor
APOGKADJ_00229 1.1e-50 yqiG C Oxidoreductase
APOGKADJ_00230 7.8e-20 yqiG C Oxidoreductase
APOGKADJ_00231 3.7e-91 yqiG C Oxidoreductase
APOGKADJ_00233 3.7e-19
APOGKADJ_00234 5e-263 dtpT U amino acid peptide transporter
APOGKADJ_00235 1.4e-158 yjjH S Calcineurin-like phosphoesterase
APOGKADJ_00238 5.5e-110
APOGKADJ_00239 2.8e-252 EGP Major facilitator Superfamily
APOGKADJ_00240 9.5e-300 aspT P Predicted Permease Membrane Region
APOGKADJ_00241 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
APOGKADJ_00242 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
APOGKADJ_00243 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APOGKADJ_00244 5.1e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APOGKADJ_00245 0.0 yhgF K Tex-like protein N-terminal domain protein
APOGKADJ_00246 5.6e-85 ydcK S Belongs to the SprT family
APOGKADJ_00248 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
APOGKADJ_00249 3.8e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
APOGKADJ_00250 0.0 S Bacterial membrane protein, YfhO
APOGKADJ_00251 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APOGKADJ_00252 3.1e-169 I alpha/beta hydrolase fold
APOGKADJ_00253 9.4e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
APOGKADJ_00254 2.4e-119 tcyB E ABC transporter
APOGKADJ_00255 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APOGKADJ_00256 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
APOGKADJ_00257 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
APOGKADJ_00258 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
APOGKADJ_00259 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
APOGKADJ_00260 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
APOGKADJ_00261 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APOGKADJ_00262 1.7e-207 yacL S domain protein
APOGKADJ_00263 8.5e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
APOGKADJ_00264 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APOGKADJ_00265 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APOGKADJ_00266 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
APOGKADJ_00267 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APOGKADJ_00268 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
APOGKADJ_00269 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APOGKADJ_00270 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APOGKADJ_00271 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
APOGKADJ_00272 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APOGKADJ_00273 1.4e-309 lmrA V ABC transporter, ATP-binding protein
APOGKADJ_00274 0.0 yfiC V ABC transporter
APOGKADJ_00275 1.1e-283 pipD E Dipeptidase
APOGKADJ_00276 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APOGKADJ_00277 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
APOGKADJ_00278 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
APOGKADJ_00279 2.7e-244 yagE E amino acid
APOGKADJ_00280 4.5e-140 aroD S Serine hydrolase (FSH1)
APOGKADJ_00281 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
APOGKADJ_00282 5.2e-167 GK ROK family
APOGKADJ_00283 0.0 tetP J elongation factor G
APOGKADJ_00284 5.1e-81 uspA T universal stress protein
APOGKADJ_00285 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
APOGKADJ_00286 7.1e-63
APOGKADJ_00287 5.2e-14
APOGKADJ_00288 1.1e-108
APOGKADJ_00289 8e-136 V ABC transporter
APOGKADJ_00290 1.4e-212 EGP Major facilitator Superfamily
APOGKADJ_00291 1.3e-257 G PTS system Galactitol-specific IIC component
APOGKADJ_00292 1.3e-179 1.6.5.5 C Zinc-binding dehydrogenase
APOGKADJ_00293 1.1e-161
APOGKADJ_00294 1e-72 K Transcriptional regulator
APOGKADJ_00295 3.7e-190 D Alpha beta
APOGKADJ_00296 2.2e-52 ypaA S Protein of unknown function (DUF1304)
APOGKADJ_00297 0.0 yjcE P Sodium proton antiporter
APOGKADJ_00298 1.6e-52 yvlA
APOGKADJ_00299 1.8e-113 P Cobalt transport protein
APOGKADJ_00300 6e-247 cbiO1 S ABC transporter, ATP-binding protein
APOGKADJ_00301 3e-96 S ABC-type cobalt transport system, permease component
APOGKADJ_00302 3.3e-133 S membrane transporter protein
APOGKADJ_00303 2.5e-138 IQ KR domain
APOGKADJ_00304 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
APOGKADJ_00305 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
APOGKADJ_00313 1.3e-143 L Belongs to the 'phage' integrase family
APOGKADJ_00314 2e-91 K AntA/AntB antirepressor
APOGKADJ_00315 2.2e-11
APOGKADJ_00317 1.8e-19 E Zn peptidase
APOGKADJ_00318 1.8e-14 XK27_10050 K Peptidase S24-like
APOGKADJ_00320 1.1e-37
APOGKADJ_00322 1.5e-12 S Hypothetical protein (DUF2513)
APOGKADJ_00326 8.4e-31
APOGKADJ_00328 1.4e-78 S Siphovirus Gp157
APOGKADJ_00329 2.5e-08
APOGKADJ_00330 4.1e-256 res L Helicase C-terminal domain protein
APOGKADJ_00331 2.1e-140 L AAA domain
APOGKADJ_00332 1.9e-92
APOGKADJ_00333 8.1e-148 S Bifunctional DNA primase/polymerase, N-terminal
APOGKADJ_00334 3e-226 S Virulence-associated protein E
APOGKADJ_00337 1.6e-57 S VRR_NUC
APOGKADJ_00338 4.3e-15
APOGKADJ_00341 1.7e-10
APOGKADJ_00346 7.2e-80 arpU S Phage transcriptional regulator, ArpU family
APOGKADJ_00347 1.2e-32
APOGKADJ_00348 1.3e-67 L Terminase small subunit
APOGKADJ_00349 8.4e-32 L NUMOD4 motif
APOGKADJ_00350 6.6e-10 S Phage terminase large subunit
APOGKADJ_00351 1.4e-223 S Phage terminase, large subunit
APOGKADJ_00352 2.1e-271 S Phage portal protein
APOGKADJ_00353 3.2e-238 S Phage Mu protein F like protein
APOGKADJ_00355 1.7e-33 S YjcQ protein
APOGKADJ_00356 2e-101 S Domain of unknown function (DUF4355)
APOGKADJ_00357 2.9e-154
APOGKADJ_00358 3.9e-66 S Phage gp6-like head-tail connector protein
APOGKADJ_00359 6.9e-50
APOGKADJ_00360 4.2e-68 S Bacteriophage HK97-gp10, putative tail-component
APOGKADJ_00361 8.4e-21 S Protein of unknown function (DUF3168)
APOGKADJ_00362 7.7e-103 S Phage tail tube protein
APOGKADJ_00363 3.2e-53 S Phage tail assembly chaperone protein, TAC
APOGKADJ_00364 2.7e-61
APOGKADJ_00365 7.5e-79 sca1 D Phage tail tape measure protein
APOGKADJ_00366 2.8e-148 S phage tail
APOGKADJ_00367 0.0 M Prophage endopeptidase tail
APOGKADJ_00369 1.4e-55 S Calcineurin-like phosphoesterase
APOGKADJ_00370 9.5e-55 S Bacteriophage holin family
APOGKADJ_00371 1.1e-30 S Bacteriophage holin of superfamily 6 (Holin_LLH)
APOGKADJ_00372 5.7e-172 M lysozyme activity
APOGKADJ_00373 1.1e-256 malT G Major Facilitator
APOGKADJ_00374 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
APOGKADJ_00375 1.9e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
APOGKADJ_00376 5.7e-71
APOGKADJ_00377 8.2e-87 2.7.6.5 T Region found in RelA / SpoT proteins
APOGKADJ_00378 3.3e-118 K response regulator
APOGKADJ_00379 4.5e-225 sptS 2.7.13.3 T Histidine kinase
APOGKADJ_00380 2.5e-209 yfeO P Voltage gated chloride channel
APOGKADJ_00381 8.1e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
APOGKADJ_00382 6.6e-136 puuD S peptidase C26
APOGKADJ_00383 3.8e-167 yvgN C Aldo keto reductase
APOGKADJ_00384 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
APOGKADJ_00385 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
APOGKADJ_00386 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
APOGKADJ_00387 4.2e-261 nox C NADH oxidase
APOGKADJ_00388 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APOGKADJ_00389 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APOGKADJ_00390 3e-86
APOGKADJ_00391 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APOGKADJ_00393 4.3e-13 K Transcriptional regulator, TetR family
APOGKADJ_00394 6.2e-76 K Transcriptional regulator, TetR family
APOGKADJ_00395 2.2e-72
APOGKADJ_00396 1.1e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
APOGKADJ_00397 1.8e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
APOGKADJ_00398 7.1e-277 M domain protein
APOGKADJ_00399 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
APOGKADJ_00400 3.2e-264 G Major Facilitator
APOGKADJ_00401 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
APOGKADJ_00402 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APOGKADJ_00403 5.7e-258 G Major Facilitator
APOGKADJ_00404 1.3e-131 K Transcriptional regulator, LacI family
APOGKADJ_00405 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
APOGKADJ_00406 0.0 comEC S Competence protein ComEC
APOGKADJ_00407 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
APOGKADJ_00408 7.6e-80 comEA L Competence protein ComEA
APOGKADJ_00409 6.7e-198 ylbL T Belongs to the peptidase S16 family
APOGKADJ_00410 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APOGKADJ_00411 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
APOGKADJ_00412 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
APOGKADJ_00413 2e-222 ftsW D Belongs to the SEDS family
APOGKADJ_00414 0.0 typA T GTP-binding protein TypA
APOGKADJ_00415 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
APOGKADJ_00416 1.4e-47 yktA S Belongs to the UPF0223 family
APOGKADJ_00417 1.2e-274 lpdA 1.8.1.4 C Dehydrogenase
APOGKADJ_00418 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APOGKADJ_00419 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
APOGKADJ_00420 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
APOGKADJ_00421 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APOGKADJ_00422 2.4e-78
APOGKADJ_00423 9.8e-32 ykzG S Belongs to the UPF0356 family
APOGKADJ_00424 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
APOGKADJ_00425 5.7e-29
APOGKADJ_00426 1.2e-133 mltD CBM50 M NlpC P60 family protein
APOGKADJ_00428 7.7e-58
APOGKADJ_00429 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
APOGKADJ_00430 3.8e-219 EG GntP family permease
APOGKADJ_00431 8.5e-84 KT Putative sugar diacid recognition
APOGKADJ_00432 3.3e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APOGKADJ_00433 5.5e-217 patA 2.6.1.1 E Aminotransferase
APOGKADJ_00434 8.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APOGKADJ_00435 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APOGKADJ_00436 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APOGKADJ_00437 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APOGKADJ_00438 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APOGKADJ_00439 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
APOGKADJ_00440 1.9e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APOGKADJ_00441 4.3e-25 UW LPXTG-motif cell wall anchor domain protein
APOGKADJ_00442 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APOGKADJ_00443 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APOGKADJ_00444 9e-119 S Repeat protein
APOGKADJ_00445 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
APOGKADJ_00446 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APOGKADJ_00447 3.7e-57 XK27_04120 S Putative amino acid metabolism
APOGKADJ_00448 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
APOGKADJ_00449 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APOGKADJ_00451 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
APOGKADJ_00452 4.2e-32 cspA K Cold shock protein
APOGKADJ_00453 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APOGKADJ_00454 1.9e-42 divIVA D DivIVA domain protein
APOGKADJ_00455 1.1e-141 ylmH S S4 domain protein
APOGKADJ_00456 3.2e-40 yggT S YGGT family
APOGKADJ_00457 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APOGKADJ_00458 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APOGKADJ_00459 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APOGKADJ_00460 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APOGKADJ_00461 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APOGKADJ_00462 2.9e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APOGKADJ_00463 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APOGKADJ_00464 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
APOGKADJ_00465 2.6e-56 ftsL D Cell division protein FtsL
APOGKADJ_00466 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APOGKADJ_00467 3.1e-77 mraZ K Belongs to the MraZ family
APOGKADJ_00468 7.3e-56
APOGKADJ_00469 1.2e-10 S Protein of unknown function (DUF4044)
APOGKADJ_00470 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
APOGKADJ_00471 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APOGKADJ_00472 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
APOGKADJ_00473 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
APOGKADJ_00477 1.6e-48 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
APOGKADJ_00478 8.6e-159 L restriction endonuclease
APOGKADJ_00479 1.1e-95 mrr L restriction endonuclease
APOGKADJ_00480 0.0 L PLD-like domain
APOGKADJ_00482 1.5e-180 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
APOGKADJ_00483 3.5e-186 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APOGKADJ_00484 9.7e-93 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
APOGKADJ_00485 2.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
APOGKADJ_00486 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
APOGKADJ_00487 1.8e-101 T Ion transport 2 domain protein
APOGKADJ_00488 0.0 S Bacterial membrane protein YfhO
APOGKADJ_00489 5e-202 G Transporter, major facilitator family protein
APOGKADJ_00490 5.4e-109 yvrI K sigma factor activity
APOGKADJ_00491 3.5e-64 ydiI Q Thioesterase superfamily
APOGKADJ_00492 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
APOGKADJ_00493 8e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
APOGKADJ_00494 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
APOGKADJ_00495 4.2e-32 feoA P FeoA domain
APOGKADJ_00496 6.5e-145 sufC O FeS assembly ATPase SufC
APOGKADJ_00497 7.3e-239 sufD O FeS assembly protein SufD
APOGKADJ_00498 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APOGKADJ_00499 1.9e-80 nifU C SUF system FeS assembly protein, NifU family
APOGKADJ_00500 1.6e-271 sufB O assembly protein SufB
APOGKADJ_00501 1.4e-56 yitW S Iron-sulfur cluster assembly protein
APOGKADJ_00502 6.1e-160 hipB K Helix-turn-helix
APOGKADJ_00503 1.3e-114 nreC K PFAM regulatory protein LuxR
APOGKADJ_00504 9.2e-39 S Cytochrome B5
APOGKADJ_00505 5.8e-157 yitU 3.1.3.104 S hydrolase
APOGKADJ_00506 1e-259 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
APOGKADJ_00507 4e-148 f42a O Band 7 protein
APOGKADJ_00508 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
APOGKADJ_00509 2.4e-130 lytT K response regulator receiver
APOGKADJ_00510 1.9e-66 lrgA S LrgA family
APOGKADJ_00511 2.6e-124 lrgB M LrgB-like family
APOGKADJ_00512 1.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APOGKADJ_00513 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
APOGKADJ_00514 9.4e-189 galR K Periplasmic binding protein-like domain
APOGKADJ_00515 0.0 rafA 3.2.1.22 G alpha-galactosidase
APOGKADJ_00516 3.8e-87 S Protein of unknown function (DUF1440)
APOGKADJ_00517 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
APOGKADJ_00518 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
APOGKADJ_00519 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
APOGKADJ_00520 5.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
APOGKADJ_00521 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
APOGKADJ_00522 2.9e-85 ypmB S Protein conserved in bacteria
APOGKADJ_00523 3e-125 dnaD L DnaD domain protein
APOGKADJ_00524 2e-161 EG EamA-like transporter family
APOGKADJ_00525 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
APOGKADJ_00526 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APOGKADJ_00527 1.6e-105 ypsA S Belongs to the UPF0398 family
APOGKADJ_00528 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APOGKADJ_00529 1.1e-83 F Belongs to the NrdI family
APOGKADJ_00530 1.9e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
APOGKADJ_00531 9e-100 L Belongs to the 'phage' integrase family
APOGKADJ_00532 4.4e-27
APOGKADJ_00533 2.1e-89 S Abi-like protein
APOGKADJ_00534 1e-38
APOGKADJ_00535 7e-09
APOGKADJ_00538 4.5e-42 E Zn peptidase
APOGKADJ_00539 1.2e-36 K Helix-turn-helix XRE-family like proteins
APOGKADJ_00541 4.6e-68 S DNA binding
APOGKADJ_00550 1.4e-11 S Bacteriophage Mu Gam like protein
APOGKADJ_00551 1.2e-42 S ERF superfamily
APOGKADJ_00552 2.4e-92 S Putative HNHc nuclease
APOGKADJ_00553 8.8e-44 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APOGKADJ_00554 2e-56 S calcium ion binding
APOGKADJ_00555 2.2e-52 dnaC 3.4.21.53 L IstB-like ATP binding protein
APOGKADJ_00563 3.1e-78 Q DNA (cytosine-5-)-methyltransferase activity
APOGKADJ_00570 1.1e-61 rusA L Endodeoxyribonuclease RusA
APOGKADJ_00573 1.7e-37
APOGKADJ_00577 9.9e-64 K Domain of unknown function (DUF4417)
APOGKADJ_00579 6e-120 xtmA L Terminase small subunit
APOGKADJ_00580 1.7e-219 S Terminase-like family
APOGKADJ_00581 2.4e-217 S Phage portal protein, SPP1 Gp6-like
APOGKADJ_00582 2.4e-150 S Phage Mu protein F like protein
APOGKADJ_00583 5.3e-52 S Domain of unknown function (DUF4355)
APOGKADJ_00584 3.1e-54
APOGKADJ_00585 1e-166 S Phage major capsid protein E
APOGKADJ_00586 2.8e-35
APOGKADJ_00587 1e-57
APOGKADJ_00588 5.6e-79
APOGKADJ_00589 5.6e-51
APOGKADJ_00590 5e-71 S Phage tail tube protein, TTP
APOGKADJ_00591 9e-58
APOGKADJ_00592 1.7e-31
APOGKADJ_00593 0.0 M Phage tail tape measure protein TP901
APOGKADJ_00594 8.4e-52
APOGKADJ_00595 0.0 GT2,GT4 LM gp58-like protein
APOGKADJ_00597 4.8e-12
APOGKADJ_00598 1.3e-15 S Bacteriophage holin family
APOGKADJ_00599 1.6e-185 M lysozyme activity
APOGKADJ_00600 4.4e-70 rnhA 3.1.26.4 L Ribonuclease HI
APOGKADJ_00601 1.5e-65 esbA S Family of unknown function (DUF5322)
APOGKADJ_00602 2.9e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APOGKADJ_00603 2.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APOGKADJ_00604 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
APOGKADJ_00605 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
APOGKADJ_00606 0.0 FbpA K Fibronectin-binding protein
APOGKADJ_00607 1.9e-161 degV S EDD domain protein, DegV family
APOGKADJ_00608 4.2e-92
APOGKADJ_00609 6.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
APOGKADJ_00610 1.1e-158 gspA M family 8
APOGKADJ_00611 1.2e-160 S Alpha beta hydrolase
APOGKADJ_00612 1.5e-94 K Acetyltransferase (GNAT) domain
APOGKADJ_00613 3.5e-152 XK27_08635 S UPF0210 protein
APOGKADJ_00614 8.5e-73 XK27_08635 S UPF0210 protein
APOGKADJ_00615 2.1e-39 gcvR T Belongs to the UPF0237 family
APOGKADJ_00616 1.9e-169 1.1.1.346 C Aldo keto reductase
APOGKADJ_00617 1.1e-158 K LysR substrate binding domain protein
APOGKADJ_00618 3.2e-83 C Flavodoxin
APOGKADJ_00619 5.6e-79 yphH S Cupin domain
APOGKADJ_00620 1e-73 yeaL S UPF0756 membrane protein
APOGKADJ_00621 1.3e-244 EGP Major facilitator Superfamily
APOGKADJ_00622 5e-75 copY K Copper transport repressor CopY TcrY
APOGKADJ_00623 2.5e-245 yhdP S Transporter associated domain
APOGKADJ_00624 0.0 ubiB S ABC1 family
APOGKADJ_00625 9.6e-144 S DUF218 domain
APOGKADJ_00626 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APOGKADJ_00627 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APOGKADJ_00628 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APOGKADJ_00629 0.0 uvrA3 L excinuclease ABC, A subunit
APOGKADJ_00630 4.6e-123 S SNARE associated Golgi protein
APOGKADJ_00631 8.4e-216 N Uncharacterized conserved protein (DUF2075)
APOGKADJ_00632 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APOGKADJ_00634 1e-254 yifK E Amino acid permease
APOGKADJ_00635 8.7e-156 endA V DNA/RNA non-specific endonuclease
APOGKADJ_00636 5.4e-41 L Belongs to the 'phage' integrase family
APOGKADJ_00640 2.9e-39 S hydrolase activity
APOGKADJ_00642 9.2e-29
APOGKADJ_00645 6.2e-09 K Helix-turn-helix domain
APOGKADJ_00646 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
APOGKADJ_00647 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
APOGKADJ_00648 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
APOGKADJ_00649 4.8e-88 GM epimerase
APOGKADJ_00650 1.7e-154 ypdB V (ABC) transporter
APOGKADJ_00651 6.2e-241 yhdP S Transporter associated domain
APOGKADJ_00652 9.9e-85 nrdI F Belongs to the NrdI family
APOGKADJ_00653 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
APOGKADJ_00654 3.1e-193 yeaN P Transporter, major facilitator family protein
APOGKADJ_00655 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APOGKADJ_00656 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APOGKADJ_00657 5.5e-40
APOGKADJ_00658 4.9e-287 lacS G Transporter
APOGKADJ_00659 2.4e-62 ltrA S Bacterial low temperature requirement A protein (LtrA)
APOGKADJ_00660 3.8e-49 ltrA S Bacterial low temperature requirement A protein (LtrA)
APOGKADJ_00661 1.5e-80 uspA T universal stress protein
APOGKADJ_00662 1.5e-80 K AsnC family
APOGKADJ_00663 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APOGKADJ_00664 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
APOGKADJ_00665 2e-180 galR K Transcriptional regulator
APOGKADJ_00666 2.2e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
APOGKADJ_00667 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APOGKADJ_00668 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
APOGKADJ_00669 1.5e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
APOGKADJ_00670 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
APOGKADJ_00671 9.1e-36
APOGKADJ_00672 5.9e-52
APOGKADJ_00673 2.5e-203
APOGKADJ_00674 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APOGKADJ_00675 8.9e-136 pnuC H nicotinamide mononucleotide transporter
APOGKADJ_00676 3e-156 ytbE 1.1.1.346 S Aldo keto reductase
APOGKADJ_00677 2.2e-179 T PhoQ Sensor
APOGKADJ_00678 2.6e-135 macB2 V ABC transporter, ATP-binding protein
APOGKADJ_00679 0.0 ysaB V FtsX-like permease family
APOGKADJ_00680 1.2e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
APOGKADJ_00681 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APOGKADJ_00682 5.3e-20 K helix_turn_helix, mercury resistance
APOGKADJ_00683 1.2e-78 2.7.13.3 T GHKL domain
APOGKADJ_00685 1.3e-260 S Putative peptidoglycan binding domain
APOGKADJ_00686 3.5e-35
APOGKADJ_00687 2.5e-212 bacI V MacB-like periplasmic core domain
APOGKADJ_00688 4.4e-129 V ABC transporter
APOGKADJ_00689 5.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APOGKADJ_00690 2.3e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
APOGKADJ_00691 3.9e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APOGKADJ_00692 3e-147 E Glyoxalase-like domain
APOGKADJ_00693 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
APOGKADJ_00694 2.9e-96 S reductase
APOGKADJ_00696 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APOGKADJ_00697 4.7e-177 ABC-SBP S ABC transporter
APOGKADJ_00698 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
APOGKADJ_00699 9.6e-215 htrA 3.4.21.107 O serine protease
APOGKADJ_00700 4.5e-154 vicX 3.1.26.11 S domain protein
APOGKADJ_00701 2.7e-149 yycI S YycH protein
APOGKADJ_00702 2.1e-246 yycH S YycH protein
APOGKADJ_00703 0.0 vicK 2.7.13.3 T Histidine kinase
APOGKADJ_00704 6.8e-130 K response regulator
APOGKADJ_00706 6.2e-310 lmrA 3.6.3.44 V ABC transporter
APOGKADJ_00707 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
APOGKADJ_00709 1.8e-215 L Integrase core domain
APOGKADJ_00710 4.8e-126 O Bacterial dnaA protein
APOGKADJ_00711 9.8e-09 K DNA-binding helix-turn-helix protein
APOGKADJ_00712 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
APOGKADJ_00713 3.7e-54
APOGKADJ_00714 9.9e-206 yttB EGP Major facilitator Superfamily
APOGKADJ_00715 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
APOGKADJ_00716 2e-74 rplI J Binds to the 23S rRNA
APOGKADJ_00717 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
APOGKADJ_00718 7.4e-134 K LysR substrate binding domain
APOGKADJ_00719 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
APOGKADJ_00720 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APOGKADJ_00721 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APOGKADJ_00722 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APOGKADJ_00723 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APOGKADJ_00724 4.8e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
APOGKADJ_00725 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APOGKADJ_00726 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
APOGKADJ_00727 4.9e-177 K AI-2E family transporter
APOGKADJ_00728 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
APOGKADJ_00729 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
APOGKADJ_00730 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
APOGKADJ_00731 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APOGKADJ_00732 2.3e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APOGKADJ_00733 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APOGKADJ_00734 5.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
APOGKADJ_00735 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APOGKADJ_00736 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APOGKADJ_00737 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APOGKADJ_00738 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APOGKADJ_00739 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
APOGKADJ_00740 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APOGKADJ_00741 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
APOGKADJ_00742 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
APOGKADJ_00743 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APOGKADJ_00744 1.5e-173
APOGKADJ_00745 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APOGKADJ_00746 4.2e-77 marR K Transcriptional regulator, MarR family
APOGKADJ_00747 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APOGKADJ_00749 2.8e-199 xerS L Belongs to the 'phage' integrase family
APOGKADJ_00750 2.6e-162 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
APOGKADJ_00751 3.3e-60 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
APOGKADJ_00752 1.4e-158 rssA S Phospholipase, patatin family
APOGKADJ_00753 2.5e-118 L Integrase
APOGKADJ_00754 1.2e-152 EG EamA-like transporter family
APOGKADJ_00755 4e-234 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APOGKADJ_00756 2.5e-129 narI 1.7.5.1 C Nitrate reductase
APOGKADJ_00757 2.7e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
APOGKADJ_00758 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
APOGKADJ_00759 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APOGKADJ_00760 8.8e-187 moeB 2.7.7.73, 2.7.7.80 H ThiF family
APOGKADJ_00761 3.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
APOGKADJ_00762 4.2e-228 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
APOGKADJ_00763 2.6e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
APOGKADJ_00764 8.9e-96 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
APOGKADJ_00765 2.6e-43
APOGKADJ_00766 8.8e-182 comP 2.7.13.3 F Sensor histidine kinase
APOGKADJ_00767 9.8e-115 nreC K PFAM regulatory protein LuxR
APOGKADJ_00768 1.2e-18
APOGKADJ_00769 4e-173
APOGKADJ_00770 1.1e-143 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
APOGKADJ_00771 1.5e-217 narK P Transporter, major facilitator family protein
APOGKADJ_00772 1.1e-31 moaD 2.8.1.12 H ThiS family
APOGKADJ_00773 1.6e-62 moaE 2.8.1.12 H MoaE protein
APOGKADJ_00774 2.4e-80 S Flavodoxin
APOGKADJ_00775 5.4e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APOGKADJ_00776 2.7e-135 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
APOGKADJ_00777 7.7e-175 fecB P Periplasmic binding protein
APOGKADJ_00778 5.7e-172
APOGKADJ_00779 1.1e-72
APOGKADJ_00780 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APOGKADJ_00783 8.7e-248 V Type II restriction enzyme, methylase subunits
APOGKADJ_00784 4.3e-52 dps P Belongs to the Dps family
APOGKADJ_00785 5.9e-72 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
APOGKADJ_00786 1.4e-183 amtB P ammonium transporter
APOGKADJ_00787 2.2e-65 yybA 2.3.1.57 K Transcriptional regulator
APOGKADJ_00788 2e-76 XK27_07210 6.1.1.6 S B3 4 domain
APOGKADJ_00789 3e-76 XK27_08850 J Aminoacyl-tRNA editing domain
APOGKADJ_00790 6e-143 gntT EG Gluconate
APOGKADJ_00791 6.1e-71 S Membrane transport protein
APOGKADJ_00792 2.3e-227 gudD 4.2.1.40 M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
APOGKADJ_00793 3.1e-66 K LysR substrate binding domain
APOGKADJ_00794 6.1e-128 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
APOGKADJ_00795 8.4e-160 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
APOGKADJ_00796 3.9e-123 mcyI 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
APOGKADJ_00797 8.6e-177 P Sodium:sulfate symporter transmembrane region
APOGKADJ_00798 2.2e-117 L Integrase core domain
APOGKADJ_00799 3.8e-79 L Integrase core domain
APOGKADJ_00800 5.1e-41 O Bacterial dnaA protein
APOGKADJ_00801 3e-144 L PFAM Integrase catalytic region
APOGKADJ_00802 2.8e-106 tra L Transposase and inactivated derivatives, IS30 family
APOGKADJ_00803 2.1e-126
APOGKADJ_00804 3.3e-55 S Sugar efflux transporter for intercellular exchange
APOGKADJ_00805 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
APOGKADJ_00807 1.3e-226 aadAT EK Aminotransferase, class I
APOGKADJ_00809 6.2e-246 M Glycosyl transferase family group 2
APOGKADJ_00810 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APOGKADJ_00811 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APOGKADJ_00812 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APOGKADJ_00813 2.6e-48
APOGKADJ_00815 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APOGKADJ_00816 4e-56 K transcriptional regulator PadR family
APOGKADJ_00817 1e-81 XK27_06920 S Protein of unknown function (DUF1700)
APOGKADJ_00818 6.4e-126 S Putative adhesin
APOGKADJ_00819 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
APOGKADJ_00820 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APOGKADJ_00821 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APOGKADJ_00822 3.4e-35 nrdH O Glutaredoxin
APOGKADJ_00823 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APOGKADJ_00824 8.1e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APOGKADJ_00825 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APOGKADJ_00826 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APOGKADJ_00827 2.8e-38 S Protein of unknown function (DUF2508)
APOGKADJ_00828 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APOGKADJ_00829 7.6e-52 yaaQ S Cyclic-di-AMP receptor
APOGKADJ_00830 2.8e-185 holB 2.7.7.7 L DNA polymerase III
APOGKADJ_00831 5.9e-58 yabA L Involved in initiation control of chromosome replication
APOGKADJ_00832 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APOGKADJ_00833 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
APOGKADJ_00834 3.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
APOGKADJ_00835 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
APOGKADJ_00836 5.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
APOGKADJ_00837 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
APOGKADJ_00838 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APOGKADJ_00839 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APOGKADJ_00840 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
APOGKADJ_00841 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APOGKADJ_00842 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APOGKADJ_00843 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APOGKADJ_00844 1.7e-34 yaaA S S4 domain protein YaaA
APOGKADJ_00845 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
APOGKADJ_00846 1.6e-81 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
APOGKADJ_00847 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APOGKADJ_00848 6.5e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APOGKADJ_00849 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
APOGKADJ_00850 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APOGKADJ_00851 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APOGKADJ_00852 1.1e-128 jag S R3H domain protein
APOGKADJ_00853 8.7e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APOGKADJ_00854 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APOGKADJ_00855 0.0 asnB 6.3.5.4 E Asparagine synthase
APOGKADJ_00856 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APOGKADJ_00857 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
APOGKADJ_00858 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
APOGKADJ_00859 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
APOGKADJ_00860 1.8e-161 S reductase
APOGKADJ_00862 3.6e-288 S amidohydrolase
APOGKADJ_00863 9.4e-164 K Aminotransferase class I and II
APOGKADJ_00864 7.3e-60 K Aminotransferase class I and II
APOGKADJ_00865 1.9e-13 azlC E azaleucine resistance protein AzlC
APOGKADJ_00868 3.9e-284 S Protein of unknown function DUF262
APOGKADJ_00869 0.0 L Type III restriction enzyme, res subunit
APOGKADJ_00870 1.5e-101 2.1.1.72, 3.1.21.4 L site-specific DNA-methyltransferase (adenine-specific) activity
APOGKADJ_00871 8.9e-80 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
APOGKADJ_00873 7.7e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APOGKADJ_00874 1.8e-34 doc S Fic/DOC family
APOGKADJ_00875 2e-12
APOGKADJ_00876 5.1e-187 yegS 2.7.1.107 G Lipid kinase
APOGKADJ_00877 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APOGKADJ_00878 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APOGKADJ_00879 2e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APOGKADJ_00880 2.1e-202 camS S sex pheromone
APOGKADJ_00881 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APOGKADJ_00882 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
APOGKADJ_00883 1.1e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
APOGKADJ_00884 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APOGKADJ_00885 6.1e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
APOGKADJ_00886 3.6e-140 IQ reductase
APOGKADJ_00887 1.1e-53 P Cadmium resistance transporter
APOGKADJ_00888 6.8e-56 K Transcriptional regulator, ArsR family
APOGKADJ_00889 7.3e-54 M Leucine-rich repeat (LRR) protein
APOGKADJ_00890 1.6e-236 mepA V MATE efflux family protein
APOGKADJ_00891 2.1e-54 trxA O Belongs to the thioredoxin family
APOGKADJ_00892 2.3e-131 terC P membrane
APOGKADJ_00893 4.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APOGKADJ_00894 2.2e-168 corA P CorA-like Mg2+ transporter protein
APOGKADJ_00895 6.7e-304 L Transposase
APOGKADJ_00896 1.4e-283 pipD E Dipeptidase
APOGKADJ_00897 1.6e-241 pbuX F xanthine permease
APOGKADJ_00898 1.8e-251 nhaC C Na H antiporter NhaC
APOGKADJ_00899 1.4e-284 S C4-dicarboxylate anaerobic carrier
APOGKADJ_00900 3e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
APOGKADJ_00901 1.3e-41
APOGKADJ_00902 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APOGKADJ_00903 1.7e-207 gldA 1.1.1.6 C dehydrogenase
APOGKADJ_00904 5.5e-126 S Alpha beta hydrolase
APOGKADJ_00905 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
APOGKADJ_00906 2.5e-101
APOGKADJ_00908 6.8e-124 yciB M ErfK YbiS YcfS YnhG
APOGKADJ_00909 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
APOGKADJ_00910 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
APOGKADJ_00911 5.2e-254 yagE E amino acid
APOGKADJ_00912 3.4e-85 dps P Belongs to the Dps family
APOGKADJ_00913 0.0 pacL 3.6.3.8 P P-type ATPase
APOGKADJ_00914 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
APOGKADJ_00915 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
APOGKADJ_00916 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
APOGKADJ_00917 4.5e-146 potB P ABC transporter permease
APOGKADJ_00918 4.9e-140 potC P ABC transporter permease
APOGKADJ_00919 1.2e-207 potD P ABC transporter
APOGKADJ_00920 8.1e-230
APOGKADJ_00921 7.2e-234 EGP Sugar (and other) transporter
APOGKADJ_00922 3e-254 yfnA E Amino Acid
APOGKADJ_00923 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
APOGKADJ_00924 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
APOGKADJ_00925 1.5e-82 zur P Belongs to the Fur family
APOGKADJ_00926 4e-17 3.2.1.14 GH18
APOGKADJ_00927 4.9e-151
APOGKADJ_00928 9.8e-39 pspC KT positive regulation of macromolecule biosynthetic process
APOGKADJ_00929 1.6e-94 K Transcriptional regulator (TetR family)
APOGKADJ_00930 2e-220 V domain protein
APOGKADJ_00931 1.2e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APOGKADJ_00932 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APOGKADJ_00933 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
APOGKADJ_00934 5.6e-115 rlpA M PFAM NLP P60 protein
APOGKADJ_00935 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APOGKADJ_00936 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APOGKADJ_00937 2e-58 yodB K Transcriptional regulator, HxlR family
APOGKADJ_00938 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
APOGKADJ_00939 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APOGKADJ_00940 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
APOGKADJ_00941 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APOGKADJ_00942 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
APOGKADJ_00943 4.4e-231 V MatE
APOGKADJ_00944 7.4e-267 yjeM E Amino Acid
APOGKADJ_00945 4.1e-278 arlS 2.7.13.3 T Histidine kinase
APOGKADJ_00946 1.5e-121 K response regulator
APOGKADJ_00947 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
APOGKADJ_00948 2.9e-99 yceD S Uncharacterized ACR, COG1399
APOGKADJ_00949 2.1e-213 ylbM S Belongs to the UPF0348 family
APOGKADJ_00950 1.7e-139 yqeM Q Methyltransferase
APOGKADJ_00951 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APOGKADJ_00952 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
APOGKADJ_00953 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APOGKADJ_00954 1.9e-47 yhbY J RNA-binding protein
APOGKADJ_00955 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
APOGKADJ_00956 1.8e-95 yqeG S HAD phosphatase, family IIIA
APOGKADJ_00957 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APOGKADJ_00958 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
APOGKADJ_00959 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APOGKADJ_00960 1.1e-170 dnaI L Primosomal protein DnaI
APOGKADJ_00961 6.8e-203 dnaB L replication initiation and membrane attachment
APOGKADJ_00962 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APOGKADJ_00963 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APOGKADJ_00964 9.7e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APOGKADJ_00965 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APOGKADJ_00966 4.1e-116 yoaK S Protein of unknown function (DUF1275)
APOGKADJ_00967 1.9e-119 ybhL S Belongs to the BI1 family
APOGKADJ_00968 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
APOGKADJ_00969 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
APOGKADJ_00970 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
APOGKADJ_00971 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APOGKADJ_00972 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
APOGKADJ_00973 7.5e-58 ytzB S Small secreted protein
APOGKADJ_00974 9.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
APOGKADJ_00975 8.8e-184 iolS C Aldo keto reductase
APOGKADJ_00976 2.1e-79 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
APOGKADJ_00977 1.1e-144 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
APOGKADJ_00978 7.5e-253 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
APOGKADJ_00979 5e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
APOGKADJ_00980 7.7e-27 S YSIRK type signal peptide
APOGKADJ_00981 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APOGKADJ_00982 5.1e-218 ecsB U ABC transporter
APOGKADJ_00983 3.9e-136 ecsA V ABC transporter, ATP-binding protein
APOGKADJ_00984 1.2e-76 hit FG histidine triad
APOGKADJ_00986 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APOGKADJ_00987 0.0 L AAA domain
APOGKADJ_00988 1.8e-220 yhaO L Ser Thr phosphatase family protein
APOGKADJ_00989 3.5e-40 yheA S Belongs to the UPF0342 family
APOGKADJ_00990 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APOGKADJ_00991 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
APOGKADJ_00992 2.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APOGKADJ_00993 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APOGKADJ_00995 3.3e-40
APOGKADJ_00996 1.8e-43
APOGKADJ_00997 1.3e-215 folP 2.5.1.15 H dihydropteroate synthase
APOGKADJ_00998 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
APOGKADJ_00999 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
APOGKADJ_01000 2.4e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
APOGKADJ_01001 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
APOGKADJ_01002 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APOGKADJ_01004 1.6e-42
APOGKADJ_01005 2.6e-118 S CAAX protease self-immunity
APOGKADJ_01006 2.1e-32
APOGKADJ_01007 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APOGKADJ_01008 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
APOGKADJ_01009 3.8e-113
APOGKADJ_01010 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
APOGKADJ_01011 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APOGKADJ_01012 1.2e-85 uspA T Belongs to the universal stress protein A family
APOGKADJ_01013 5.6e-277 pepV 3.5.1.18 E dipeptidase PepV
APOGKADJ_01014 6.5e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APOGKADJ_01015 4.1e-303 ytgP S Polysaccharide biosynthesis protein
APOGKADJ_01016 4.9e-41
APOGKADJ_01017 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
APOGKADJ_01018 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APOGKADJ_01019 9.6e-92 tag 3.2.2.20 L glycosylase
APOGKADJ_01020 1.5e-253 EGP Major facilitator Superfamily
APOGKADJ_01021 4.3e-85 perR P Belongs to the Fur family
APOGKADJ_01022 1.1e-232 cycA E Amino acid permease
APOGKADJ_01023 2.8e-102 V VanZ like family
APOGKADJ_01024 1e-23
APOGKADJ_01025 7.7e-86 S Short repeat of unknown function (DUF308)
APOGKADJ_01026 2.9e-78 S Psort location Cytoplasmic, score
APOGKADJ_01027 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
APOGKADJ_01028 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
APOGKADJ_01029 8.1e-154 yeaE S Aldo keto
APOGKADJ_01030 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
APOGKADJ_01031 6.9e-167 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
APOGKADJ_01032 6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
APOGKADJ_01033 2.3e-93 lytE M LysM domain protein
APOGKADJ_01034 0.0 oppD EP Psort location Cytoplasmic, score
APOGKADJ_01035 4.7e-79 lytE M LysM domain protein
APOGKADJ_01036 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
APOGKADJ_01037 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APOGKADJ_01038 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
APOGKADJ_01039 1.5e-237 lmrB EGP Major facilitator Superfamily
APOGKADJ_01040 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
APOGKADJ_01041 1.4e-14
APOGKADJ_01042 2.6e-56 S DNA primase
APOGKADJ_01046 4.5e-36 S HNH endonuclease
APOGKADJ_01048 1.7e-15 L Phage regulatory protein
APOGKADJ_01050 3.5e-13 K Transcriptional
APOGKADJ_01051 1.1e-34 S Domain of unknown function (DUF5067)
APOGKADJ_01052 1e-132 L Belongs to the 'phage' integrase family
APOGKADJ_01053 2.1e-87
APOGKADJ_01054 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APOGKADJ_01055 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
APOGKADJ_01056 1.2e-154 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
APOGKADJ_01057 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APOGKADJ_01058 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APOGKADJ_01059 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APOGKADJ_01060 1.3e-08
APOGKADJ_01061 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
APOGKADJ_01062 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
APOGKADJ_01063 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APOGKADJ_01064 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APOGKADJ_01065 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APOGKADJ_01066 3.5e-163 S Tetratricopeptide repeat
APOGKADJ_01067 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APOGKADJ_01068 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APOGKADJ_01069 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
APOGKADJ_01070 8.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APOGKADJ_01071 1.3e-114 comFC S Competence protein
APOGKADJ_01072 1.4e-256 comFA L Helicase C-terminal domain protein
APOGKADJ_01073 2.9e-111 yvyE 3.4.13.9 S YigZ family
APOGKADJ_01074 1.1e-235 EGP Major facilitator Superfamily
APOGKADJ_01075 7.4e-68 rmaI K Transcriptional regulator
APOGKADJ_01076 9.2e-40
APOGKADJ_01077 0.0 ydaO E amino acid
APOGKADJ_01078 7.3e-305 ybeC E amino acid
APOGKADJ_01079 4.1e-81 S YbaK proline--tRNA ligase associated domain protein
APOGKADJ_01080 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APOGKADJ_01081 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APOGKADJ_01083 1.4e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APOGKADJ_01084 0.0 uup S ABC transporter, ATP-binding protein
APOGKADJ_01085 4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APOGKADJ_01086 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
APOGKADJ_01087 6.6e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
APOGKADJ_01088 1.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APOGKADJ_01089 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APOGKADJ_01090 4.7e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APOGKADJ_01091 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APOGKADJ_01092 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
APOGKADJ_01093 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
APOGKADJ_01094 7.8e-272 S ABC transporter, ATP-binding protein
APOGKADJ_01095 2.3e-142 S Putative ABC-transporter type IV
APOGKADJ_01096 2e-106 NU mannosyl-glycoprotein
APOGKADJ_01097 9.3e-248 brnQ U Component of the transport system for branched-chain amino acids
APOGKADJ_01098 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
APOGKADJ_01099 7.6e-205 nrnB S DHHA1 domain
APOGKADJ_01101 6.9e-49
APOGKADJ_01102 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
APOGKADJ_01103 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
APOGKADJ_01104 2e-15 S Domain of unknown function (DUF4767)
APOGKADJ_01105 9.5e-55
APOGKADJ_01106 5.4e-116 yrkL S Flavodoxin-like fold
APOGKADJ_01108 1.6e-64 yeaO S Protein of unknown function, DUF488
APOGKADJ_01109 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
APOGKADJ_01110 3e-204 3.1.3.1 S associated with various cellular activities
APOGKADJ_01111 5.4e-242 S Putative metallopeptidase domain
APOGKADJ_01112 5.1e-47
APOGKADJ_01113 0.0 pepO 3.4.24.71 O Peptidase family M13
APOGKADJ_01114 8.4e-111 K Helix-turn-helix domain
APOGKADJ_01115 3.5e-88 ymdB S Macro domain protein
APOGKADJ_01116 1.6e-197 EGP Major facilitator Superfamily
APOGKADJ_01117 2.1e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APOGKADJ_01118 4.7e-63 L transposase and inactivated derivatives, IS30 family
APOGKADJ_01119 9.5e-172 deoR K sugar-binding domain protein
APOGKADJ_01120 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
APOGKADJ_01121 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
APOGKADJ_01122 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
APOGKADJ_01123 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APOGKADJ_01124 1.5e-135 XK27_01040 S Protein of unknown function (DUF1129)
APOGKADJ_01125 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APOGKADJ_01126 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
APOGKADJ_01127 3.8e-154 spo0J K Belongs to the ParB family
APOGKADJ_01128 3.9e-139 soj D Sporulation initiation inhibitor
APOGKADJ_01129 3.3e-151 noc K Belongs to the ParB family
APOGKADJ_01130 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
APOGKADJ_01131 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
APOGKADJ_01132 5.6e-169 rihC 3.2.2.1 F Nucleoside
APOGKADJ_01133 6.7e-218 nupG F Nucleoside transporter
APOGKADJ_01134 3.2e-221 cycA E Amino acid permease
APOGKADJ_01136 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APOGKADJ_01137 1.2e-264 glnP P ABC transporter
APOGKADJ_01138 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APOGKADJ_01139 4.5e-160 L hmm pf00665
APOGKADJ_01140 4.4e-100 L Helix-turn-helix domain
APOGKADJ_01141 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
APOGKADJ_01142 1.5e-172 malR K Transcriptional regulator, LacI family
APOGKADJ_01143 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
APOGKADJ_01144 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
APOGKADJ_01145 6.1e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APOGKADJ_01146 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
APOGKADJ_01148 0.0 clpL O associated with various cellular activities
APOGKADJ_01149 7.8e-32
APOGKADJ_01150 1.4e-215 patA 2.6.1.1 E Aminotransferase
APOGKADJ_01151 3.1e-176 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APOGKADJ_01152 5e-75 osmC O OsmC-like protein
APOGKADJ_01155 2.6e-14
APOGKADJ_01156 1.7e-62 S Bacteriophage holin of superfamily 6 (Holin_LLH)
APOGKADJ_01157 7.5e-200 ps461 3.5.1.104 M hydrolase, family 25
APOGKADJ_01158 2e-30
APOGKADJ_01159 1.6e-88 K IrrE N-terminal-like domain
APOGKADJ_01160 4.1e-275 pipD E Dipeptidase
APOGKADJ_01161 4e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
APOGKADJ_01163 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APOGKADJ_01165 2.8e-57
APOGKADJ_01166 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
APOGKADJ_01167 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APOGKADJ_01168 1.2e-52
APOGKADJ_01169 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APOGKADJ_01170 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APOGKADJ_01171 1e-164 yniA G Phosphotransferase enzyme family
APOGKADJ_01172 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
APOGKADJ_01173 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APOGKADJ_01174 5.9e-264 glnPH2 P ABC transporter permease
APOGKADJ_01175 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
APOGKADJ_01176 3.8e-70 yqeY S YqeY-like protein
APOGKADJ_01177 9.2e-178 L PFAM Integrase catalytic region
APOGKADJ_01178 7.5e-61 L Resolvase, N terminal domain
APOGKADJ_01179 2.7e-127 tesE Q hydratase
APOGKADJ_01180 2e-116 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APOGKADJ_01188 9e-41 L Psort location Cytoplasmic, score 8.96
APOGKADJ_01189 1.1e-38 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
APOGKADJ_01190 3e-16 L transposase and inactivated derivatives, IS30 family
APOGKADJ_01191 5e-128 yocS S Transporter
APOGKADJ_01192 1e-27 XK27_02560 S Pfam:DUF59
APOGKADJ_01193 7.6e-260 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
APOGKADJ_01194 2.1e-106 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
APOGKADJ_01195 0.0 ilvD 4.2.1.9 EG Belongs to the IlvD Edd family
APOGKADJ_01196 1.2e-39 S Iron-sulfur cluster assembly protein
APOGKADJ_01197 3e-155 yocS S SBF-like CPA transporter family (DUF4137)
APOGKADJ_01199 1.2e-193 nss M transferase activity, transferring glycosyl groups
APOGKADJ_01200 1.5e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
APOGKADJ_01201 1.7e-287 M transferase activity, transferring glycosyl groups
APOGKADJ_01202 1.4e-286 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
APOGKADJ_01203 4.5e-163 asp3 S Accessory Sec secretory system ASP3
APOGKADJ_01204 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APOGKADJ_01205 6.8e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
APOGKADJ_01206 1.5e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
APOGKADJ_01208 0.0 M family 8
APOGKADJ_01209 5.1e-287 GT2,GT4 M family 8
APOGKADJ_01212 0.0 S SEC-C Motif Domain Protein
APOGKADJ_01213 5.2e-50
APOGKADJ_01214 2.1e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
APOGKADJ_01215 2.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APOGKADJ_01216 5.1e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APOGKADJ_01217 1.2e-225 clcA_2 P Chloride transporter, ClC family
APOGKADJ_01218 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
APOGKADJ_01219 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
APOGKADJ_01229 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
APOGKADJ_01230 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
APOGKADJ_01231 5.1e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APOGKADJ_01232 3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
APOGKADJ_01233 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APOGKADJ_01234 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APOGKADJ_01235 2.6e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APOGKADJ_01236 3.5e-129 IQ reductase
APOGKADJ_01237 4.2e-159 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
APOGKADJ_01238 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APOGKADJ_01239 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APOGKADJ_01240 3.2e-80 L transposase and inactivated derivatives, IS30 family
APOGKADJ_01241 2.7e-68 L Belongs to the 'phage' integrase family
APOGKADJ_01242 5.8e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
APOGKADJ_01243 4.2e-130 IQ Dehydrogenase reductase
APOGKADJ_01244 2.9e-37
APOGKADJ_01245 4.8e-114 ywnB S NAD(P)H-binding
APOGKADJ_01246 7.7e-38 S Cytochrome b5-like Heme/Steroid binding domain
APOGKADJ_01247 1.2e-255 nhaC C Na H antiporter NhaC
APOGKADJ_01248 6e-109 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APOGKADJ_01249 7.8e-62 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APOGKADJ_01251 2.1e-102 ydeN S Serine hydrolase
APOGKADJ_01252 1.1e-36 psiE S Phosphate-starvation-inducible E
APOGKADJ_01253 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APOGKADJ_01255 9.7e-144 K helix_turn_helix, arabinose operon control protein
APOGKADJ_01256 5.4e-86 S Membrane
APOGKADJ_01257 0.0 rafA 3.2.1.22 G alpha-galactosidase
APOGKADJ_01258 7.7e-177 S Aldo keto reductase
APOGKADJ_01259 3.6e-77 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
APOGKADJ_01260 0.0 L Helicase C-terminal domain protein
APOGKADJ_01261 2.1e-227 L COG3547 Transposase and inactivated derivatives
APOGKADJ_01262 3.7e-221 norA EGP Major facilitator Superfamily
APOGKADJ_01263 5.8e-40 1.3.5.4 S FMN binding
APOGKADJ_01264 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APOGKADJ_01265 1e-265 yfnA E amino acid
APOGKADJ_01266 2e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APOGKADJ_01268 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APOGKADJ_01269 0.0 helD 3.6.4.12 L DNA helicase
APOGKADJ_01270 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
APOGKADJ_01271 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
APOGKADJ_01272 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
APOGKADJ_01273 1.3e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
APOGKADJ_01274 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
APOGKADJ_01275 1.6e-177
APOGKADJ_01276 3e-130 cobB K SIR2 family
APOGKADJ_01278 3.6e-162 yunF F Protein of unknown function DUF72
APOGKADJ_01279 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APOGKADJ_01280 1.9e-155 tatD L hydrolase, TatD family
APOGKADJ_01281 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APOGKADJ_01282 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APOGKADJ_01283 6.8e-37 veg S Biofilm formation stimulator VEG
APOGKADJ_01284 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APOGKADJ_01285 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
APOGKADJ_01286 1.4e-121 fhuC P ABC transporter
APOGKADJ_01287 1.4e-118 znuB U ABC 3 transport family
APOGKADJ_01288 2.6e-149 purR 2.4.2.7 F pur operon repressor
APOGKADJ_01289 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APOGKADJ_01290 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APOGKADJ_01291 2.1e-49
APOGKADJ_01292 2.5e-147 yxeH S hydrolase
APOGKADJ_01293 5e-270 ywfO S HD domain protein
APOGKADJ_01294 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
APOGKADJ_01295 3e-66 ywiB S Domain of unknown function (DUF1934)
APOGKADJ_01296 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APOGKADJ_01297 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APOGKADJ_01298 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APOGKADJ_01299 4.6e-41 rpmE2 J Ribosomal protein L31
APOGKADJ_01300 7.7e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APOGKADJ_01301 1.3e-165 S Alpha/beta hydrolase of unknown function (DUF915)
APOGKADJ_01302 1.9e-124 srtA 3.4.22.70 M sortase family
APOGKADJ_01303 1.1e-234 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
APOGKADJ_01304 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APOGKADJ_01305 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
APOGKADJ_01306 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
APOGKADJ_01307 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APOGKADJ_01308 7e-93 lemA S LemA family
APOGKADJ_01309 2.6e-158 htpX O Belongs to the peptidase M48B family
APOGKADJ_01310 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APOGKADJ_01311 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APOGKADJ_01312 1.5e-105 L PFAM Integrase catalytic region
APOGKADJ_01313 1e-141 sprD D Domain of Unknown Function (DUF1542)
APOGKADJ_01314 6.5e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
APOGKADJ_01315 6.2e-254 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APOGKADJ_01316 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOGKADJ_01317 3.7e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
APOGKADJ_01318 4.2e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APOGKADJ_01320 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APOGKADJ_01321 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APOGKADJ_01322 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
APOGKADJ_01323 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
APOGKADJ_01324 4.7e-243 codA 3.5.4.1 F cytosine deaminase
APOGKADJ_01325 3.1e-147 tesE Q hydratase
APOGKADJ_01326 4e-113 S (CBS) domain
APOGKADJ_01327 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APOGKADJ_01328 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APOGKADJ_01329 8.1e-39 yabO J S4 domain protein
APOGKADJ_01330 3.3e-56 divIC D Septum formation initiator
APOGKADJ_01331 9.8e-67 yabR J RNA binding
APOGKADJ_01332 3.8e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APOGKADJ_01333 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
APOGKADJ_01334 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APOGKADJ_01335 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APOGKADJ_01336 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APOGKADJ_01337 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
APOGKADJ_01338 5.5e-280 O Arylsulfotransferase (ASST)
APOGKADJ_01339 5.2e-84
APOGKADJ_01340 5.4e-253 pgaC GT2 M Glycosyl transferase
APOGKADJ_01341 3.7e-140 T EAL domain
APOGKADJ_01342 3.8e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
APOGKADJ_01343 1.1e-64 yneR
APOGKADJ_01344 1.2e-112 GM NAD(P)H-binding
APOGKADJ_01345 6.1e-88 S membrane
APOGKADJ_01346 2.1e-74 S membrane
APOGKADJ_01347 1.8e-104 K Transcriptional regulator C-terminal region
APOGKADJ_01348 3.2e-118 akr5f 1.1.1.346 S reductase
APOGKADJ_01349 5.5e-27 akr5f 1.1.1.346 S reductase
APOGKADJ_01350 4.3e-40 K Transcriptional regulator
APOGKADJ_01351 4.3e-59 K Transcriptional regulator
APOGKADJ_01352 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
APOGKADJ_01353 2.3e-155 ypuA S Protein of unknown function (DUF1002)
APOGKADJ_01354 4.7e-66 GM NAD(P)H-binding
APOGKADJ_01355 3.3e-92 padR K Virulence activator alpha C-term
APOGKADJ_01356 2.3e-93 padC Q Phenolic acid decarboxylase
APOGKADJ_01357 2e-152 S Alpha beta hydrolase
APOGKADJ_01358 9.4e-32 S thiolester hydrolase activity
APOGKADJ_01359 6.3e-88 lacA S transferase hexapeptide repeat
APOGKADJ_01360 5.6e-158 K Transcriptional regulator
APOGKADJ_01361 2.7e-85 C Flavodoxin
APOGKADJ_01362 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
APOGKADJ_01363 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
APOGKADJ_01364 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
APOGKADJ_01365 5.3e-83 K Bacterial regulatory proteins, tetR family
APOGKADJ_01366 4.3e-55 yphJ 4.1.1.44 S decarboxylase
APOGKADJ_01367 3.2e-47 rpsJ J Involved in the binding of tRNA to the ribosomes
APOGKADJ_01368 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APOGKADJ_01369 1.6e-106 rplD J Forms part of the polypeptide exit tunnel
APOGKADJ_01370 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APOGKADJ_01371 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APOGKADJ_01372 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APOGKADJ_01373 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APOGKADJ_01374 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APOGKADJ_01375 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APOGKADJ_01376 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
APOGKADJ_01377 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APOGKADJ_01378 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APOGKADJ_01379 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APOGKADJ_01380 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APOGKADJ_01381 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APOGKADJ_01382 1.2e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APOGKADJ_01383 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APOGKADJ_01384 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APOGKADJ_01385 2.9e-24 rpmD J Ribosomal protein L30
APOGKADJ_01386 8.9e-64 rplO J Binds to the 23S rRNA
APOGKADJ_01387 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APOGKADJ_01388 6.8e-124 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APOGKADJ_01389 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APOGKADJ_01390 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
APOGKADJ_01391 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APOGKADJ_01392 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APOGKADJ_01393 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APOGKADJ_01394 1.1e-62 rplQ J Ribosomal protein L17
APOGKADJ_01395 2.2e-140 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APOGKADJ_01396 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APOGKADJ_01397 5.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APOGKADJ_01398 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APOGKADJ_01399 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APOGKADJ_01400 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
APOGKADJ_01403 0.0 M LPXTG-motif cell wall anchor domain protein
APOGKADJ_01404 1.5e-181 M LPXTG-motif cell wall anchor domain protein
APOGKADJ_01405 0.0 trxB2 1.8.1.9 C Thioredoxin domain
APOGKADJ_01406 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
APOGKADJ_01407 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
APOGKADJ_01408 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
APOGKADJ_01411 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APOGKADJ_01412 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
APOGKADJ_01413 2.4e-223 mdtG EGP Major facilitator Superfamily
APOGKADJ_01414 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
APOGKADJ_01415 7.8e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
APOGKADJ_01416 2.5e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APOGKADJ_01418 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
APOGKADJ_01419 1.3e-61 asp S Asp23 family, cell envelope-related function
APOGKADJ_01420 2.1e-25
APOGKADJ_01421 4.2e-95
APOGKADJ_01422 1.8e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
APOGKADJ_01423 9.9e-183 K Transcriptional regulator, LacI family
APOGKADJ_01424 2.1e-65 gntT EG Gluconate
APOGKADJ_01425 9.1e-148 gntT EG Gluconate
APOGKADJ_01426 2.9e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
APOGKADJ_01427 2.9e-96 K Acetyltransferase (GNAT) domain
APOGKADJ_01428 5.4e-47
APOGKADJ_01429 2.4e-22
APOGKADJ_01430 2.2e-44
APOGKADJ_01431 4.1e-57 yhaI S Protein of unknown function (DUF805)
APOGKADJ_01432 1.4e-139 IQ reductase
APOGKADJ_01433 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
APOGKADJ_01434 2.2e-280 hsdM 2.1.1.72 V type I restriction-modification system
APOGKADJ_01435 7.2e-74 V type I restriction modification DNA specificity domain
APOGKADJ_01436 2.6e-177 L Belongs to the 'phage' integrase family
APOGKADJ_01437 5.7e-112 P Cobalt transport protein
APOGKADJ_01438 6.5e-136 cbiO P ABC transporter
APOGKADJ_01439 3.9e-133 K Transcriptional regulatory protein, C-terminal domain protein
APOGKADJ_01440 5.1e-159 pstS P Phosphate
APOGKADJ_01441 1.2e-152 pstC P probably responsible for the translocation of the substrate across the membrane
APOGKADJ_01442 7.9e-152 pstA P Phosphate transport system permease protein PstA
APOGKADJ_01443 2e-135 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APOGKADJ_01444 5.6e-124 phoU P Plays a role in the regulation of phosphate uptake
APOGKADJ_01445 1.8e-140
APOGKADJ_01446 5.5e-242 ydaM M Glycosyl transferase
APOGKADJ_01447 1.6e-216 G Glycosyl hydrolases family 8
APOGKADJ_01448 1.9e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
APOGKADJ_01449 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
APOGKADJ_01450 1.7e-238 ktrB P Potassium uptake protein
APOGKADJ_01451 1.4e-116 ktrA P domain protein
APOGKADJ_01452 1.2e-81 Q Methyltransferase
APOGKADJ_01453 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
APOGKADJ_01454 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
APOGKADJ_01455 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APOGKADJ_01456 3.1e-103 metI P ABC transporter permease
APOGKADJ_01457 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
APOGKADJ_01458 1.2e-252 clcA P chloride
APOGKADJ_01459 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
APOGKADJ_01460 4.5e-104 proW P ABC transporter, permease protein
APOGKADJ_01461 5.1e-139 proV E ABC transporter, ATP-binding protein
APOGKADJ_01462 6.3e-109 proWZ P ABC transporter permease
APOGKADJ_01463 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
APOGKADJ_01464 9e-75 K Transcriptional regulator
APOGKADJ_01465 4.8e-154 1.6.5.2 GM NAD(P)H-binding
APOGKADJ_01467 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
APOGKADJ_01468 0.0 cadA P P-type ATPase
APOGKADJ_01469 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
APOGKADJ_01471 1.2e-154 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APOGKADJ_01472 3.5e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APOGKADJ_01473 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
APOGKADJ_01474 1.1e-153 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APOGKADJ_01475 1.6e-66 S Glycosyltransferase like family
APOGKADJ_01476 1.6e-125 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
APOGKADJ_01477 1e-64 GT2 M Glycosyl transferase, family 2
APOGKADJ_01478 2e-57 GT2 S Glycosyl transferase family 2
APOGKADJ_01480 4e-41 wbbL M PFAM Glycosyl transferase family 2
APOGKADJ_01481 8.9e-52 pglC M Bacterial sugar transferase
APOGKADJ_01482 1.7e-118 ywqD 2.7.10.1 D Capsular exopolysaccharide family
APOGKADJ_01483 7.9e-144 epsB M biosynthesis protein
APOGKADJ_01484 4.9e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
APOGKADJ_01485 1.2e-67 K Transcriptional regulator, HxlR family
APOGKADJ_01487 8.6e-35 S Transglycosylase associated protein
APOGKADJ_01488 4.1e-234 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APOGKADJ_01489 4.2e-126 3.1.3.73 G phosphoglycerate mutase
APOGKADJ_01490 1.2e-115 dedA S SNARE associated Golgi protein
APOGKADJ_01491 0.0 helD 3.6.4.12 L DNA helicase
APOGKADJ_01492 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
APOGKADJ_01493 5.6e-158 EG EamA-like transporter family
APOGKADJ_01494 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APOGKADJ_01495 3.1e-175 coaA 2.7.1.33 F Pantothenic acid kinase
APOGKADJ_01496 1.5e-225 S cog cog1373
APOGKADJ_01498 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
APOGKADJ_01500 2.1e-171 G Belongs to the glycosyl hydrolase family 6
APOGKADJ_01501 6.1e-180 MA20_14895 S Conserved hypothetical protein 698
APOGKADJ_01502 2.2e-136 I alpha/beta hydrolase fold
APOGKADJ_01503 4.4e-171 lsa S ABC transporter
APOGKADJ_01504 7.4e-180 yfeX P Peroxidase
APOGKADJ_01505 9.7e-275 arcD S C4-dicarboxylate anaerobic carrier
APOGKADJ_01506 1.7e-254 ytjP 3.5.1.18 E Dipeptidase
APOGKADJ_01507 5.3e-215 uhpT EGP Major facilitator Superfamily
APOGKADJ_01508 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
APOGKADJ_01509 4.8e-132 ponA V Beta-lactamase enzyme family
APOGKADJ_01510 2.8e-66 T Toxin-antitoxin system, toxin component, MazF family
APOGKADJ_01511 5.2e-37
APOGKADJ_01513 0.0 snf 2.7.11.1 KL domain protein
APOGKADJ_01514 5.4e-144 ywqE 3.1.3.48 GM PHP domain protein
APOGKADJ_01515 2.6e-177 M Glycosyl hydrolases family 25
APOGKADJ_01516 2.6e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
APOGKADJ_01517 0.0 sbcC L Putative exonuclease SbcCD, C subunit
APOGKADJ_01518 1.6e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
APOGKADJ_01519 6.7e-75
APOGKADJ_01520 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
APOGKADJ_01521 1.9e-25
APOGKADJ_01522 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
APOGKADJ_01523 7.2e-169 L transposase, IS605 OrfB family
APOGKADJ_01524 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
APOGKADJ_01525 1.1e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
APOGKADJ_01526 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APOGKADJ_01527 1.9e-161 mleR K LysR family
APOGKADJ_01528 5.3e-303 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
APOGKADJ_01529 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APOGKADJ_01530 1.8e-267 frdC 1.3.5.4 C FAD binding domain
APOGKADJ_01531 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
APOGKADJ_01532 1e-159 mleR K LysR family
APOGKADJ_01533 2e-250 yjjP S Putative threonine/serine exporter
APOGKADJ_01534 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
APOGKADJ_01535 8.5e-282 emrY EGP Major facilitator Superfamily
APOGKADJ_01536 3.4e-188 I Alpha beta
APOGKADJ_01537 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
APOGKADJ_01538 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APOGKADJ_01540 3e-159 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
APOGKADJ_01541 9.5e-119 S Domain of unknown function (DUF4811)
APOGKADJ_01542 1e-268 lmrB EGP Major facilitator Superfamily
APOGKADJ_01543 1.8e-72 merR K MerR HTH family regulatory protein
APOGKADJ_01544 9.3e-56
APOGKADJ_01545 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APOGKADJ_01546 1.1e-217 S CAAX protease self-immunity
APOGKADJ_01547 1.4e-108 glnP P ABC transporter permease
APOGKADJ_01548 4.2e-110 gluC P ABC transporter permease
APOGKADJ_01549 7.5e-152 glnH ET ABC transporter
APOGKADJ_01550 5.3e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APOGKADJ_01551 5.5e-83 usp1 T Belongs to the universal stress protein A family
APOGKADJ_01552 1.3e-109 S VIT family
APOGKADJ_01553 5e-117 S membrane
APOGKADJ_01554 2.6e-166 czcD P cation diffusion facilitator family transporter
APOGKADJ_01555 1.1e-124 sirR K iron dependent repressor
APOGKADJ_01556 3.5e-31 cspC K Cold shock protein
APOGKADJ_01557 3.6e-129 thrE S Putative threonine/serine exporter
APOGKADJ_01558 2.5e-80 S Threonine/Serine exporter, ThrE
APOGKADJ_01559 2.7e-120 lssY 3.6.1.27 I phosphatase
APOGKADJ_01560 2.7e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
APOGKADJ_01561 1.5e-275 lysP E amino acid
APOGKADJ_01562 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
APOGKADJ_01568 4.1e-92 S Hydrolases of the alpha beta superfamily
APOGKADJ_01569 1.3e-16 S Hydrolases of the alpha beta superfamily
APOGKADJ_01570 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
APOGKADJ_01571 4.4e-77 ctsR K Belongs to the CtsR family
APOGKADJ_01572 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APOGKADJ_01573 1e-110 K Bacterial regulatory proteins, tetR family
APOGKADJ_01574 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APOGKADJ_01575 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APOGKADJ_01576 2.2e-202 ykiI
APOGKADJ_01577 4.4e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
APOGKADJ_01578 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APOGKADJ_01579 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APOGKADJ_01580 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APOGKADJ_01582 2.6e-90 L Integrase
APOGKADJ_01583 5.3e-54 L Lactococcus lactis RepB C-terminus
APOGKADJ_01584 4e-19 yqfZ 3.2.1.17 M hydrolase, family 25
APOGKADJ_01585 6.8e-102 L Replication initiation factor
APOGKADJ_01586 3.4e-36 L Single-strand binding protein family
APOGKADJ_01587 5.2e-84 L Phage integrase, N-terminal SAM-like domain
APOGKADJ_01589 1.4e-10
APOGKADJ_01593 3.8e-90 L Lactococcus lactis RepB C-terminus
APOGKADJ_01594 2.5e-93 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
APOGKADJ_01595 1.1e-46 S MvaI/BcnI restriction endonuclease family
APOGKADJ_01596 4.5e-21 K Helix-turn-helix domain
APOGKADJ_01597 4.1e-109 M Glycosyltransferase like family 2
APOGKADJ_01598 2.6e-91 S Acyltransferase family
APOGKADJ_01599 3.3e-26
APOGKADJ_01600 4.6e-111 M repeat protein
APOGKADJ_01601 7.4e-49 M KxYKxGKxW signal domain protein
APOGKADJ_01602 2.3e-34
APOGKADJ_01603 6.6e-84 M biosynthesis protein
APOGKADJ_01604 2.5e-185 cps3F
APOGKADJ_01605 6.9e-102 S enterobacterial common antigen metabolic process
APOGKADJ_01607 1.1e-87 acmD M repeat protein
APOGKADJ_01608 5.4e-43
APOGKADJ_01609 4.6e-33 KV of ABC transporters with duplicated ATPase domains
APOGKADJ_01610 7.7e-168 aadK G Streptomycin adenylyltransferase
APOGKADJ_01611 1.3e-223 L Domain of unknown function (DUF4368)
APOGKADJ_01613 1.2e-103 L Integrase
APOGKADJ_01614 6.4e-33 S RelB antitoxin
APOGKADJ_01615 6.1e-45
APOGKADJ_01616 1.1e-281 S ATPases associated with a variety of cellular activities
APOGKADJ_01617 4.2e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
APOGKADJ_01619 5.5e-202
APOGKADJ_01621 6.1e-27
APOGKADJ_01622 6.6e-47 S dextransucrase activity
APOGKADJ_01623 1.1e-163 yueF S AI-2E family transporter
APOGKADJ_01624 2.2e-206 brpA K Cell envelope-like function transcriptional attenuator common domain protein
APOGKADJ_01625 7.5e-92 M Glycosyl transferase family 2
APOGKADJ_01626 1.3e-58
APOGKADJ_01627 7.4e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
APOGKADJ_01628 1.7e-183 S Phosphotransferase system, EIIC
APOGKADJ_01629 2.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APOGKADJ_01630 2e-162
APOGKADJ_01632 1.4e-59 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APOGKADJ_01633 6.8e-201 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
APOGKADJ_01634 1.8e-156 K LysR substrate binding domain
APOGKADJ_01635 1.8e-32 manA 5.3.1.8 G mannose-6-phosphate isomerase
APOGKADJ_01636 1.2e-75 manA 5.3.1.8 G mannose-6-phosphate isomerase
APOGKADJ_01637 3.1e-95 2.3.1.128 K acetyltransferase
APOGKADJ_01638 5.3e-160
APOGKADJ_01639 7e-41 ybaN S Protein of unknown function (DUF454)
APOGKADJ_01640 9.1e-72 S Protein of unknown function (DUF3290)
APOGKADJ_01641 6.2e-114 yviA S Protein of unknown function (DUF421)
APOGKADJ_01642 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
APOGKADJ_01643 1.3e-20
APOGKADJ_01644 8.1e-90 ntd 2.4.2.6 F Nucleoside
APOGKADJ_01645 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
APOGKADJ_01646 1.6e-45 yrvD S Pfam:DUF1049
APOGKADJ_01648 1.1e-35 S Phage derived protein Gp49-like (DUF891)
APOGKADJ_01649 8.5e-20 K Helix-turn-helix XRE-family like proteins
APOGKADJ_01650 1.7e-78 I alpha/beta hydrolase fold
APOGKADJ_01651 1.1e-113 frnE Q DSBA-like thioredoxin domain
APOGKADJ_01652 2e-53
APOGKADJ_01653 7.9e-188 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
APOGKADJ_01654 4e-28 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
APOGKADJ_01655 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
APOGKADJ_01656 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APOGKADJ_01657 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
APOGKADJ_01658 4.7e-114 yjbH Q Thioredoxin
APOGKADJ_01659 2.7e-263 pipD E Dipeptidase
APOGKADJ_01660 3e-203 coiA 3.6.4.12 S Competence protein
APOGKADJ_01661 2.7e-120 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
APOGKADJ_01662 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APOGKADJ_01663 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
APOGKADJ_01665 5.9e-191 V Beta-lactamase
APOGKADJ_01666 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
APOGKADJ_01667 5e-122 yhiD S MgtC family
APOGKADJ_01668 6.4e-39 S GyrI-like small molecule binding domain
APOGKADJ_01669 2.7e-70 S GyrI-like small molecule binding domain
APOGKADJ_01670 0.0 tetP J Elongation factor G, domain IV
APOGKADJ_01671 2.3e-30 K Cro/C1-type HTH DNA-binding domain
APOGKADJ_01673 3.3e-277 pipD E Dipeptidase
APOGKADJ_01674 0.0 yjbQ P TrkA C-terminal domain protein
APOGKADJ_01675 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
APOGKADJ_01676 4.3e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APOGKADJ_01677 9e-84
APOGKADJ_01678 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APOGKADJ_01679 2.7e-39 ptsH G phosphocarrier protein HPR
APOGKADJ_01680 2.9e-27
APOGKADJ_01681 0.0 clpE O Belongs to the ClpA ClpB family
APOGKADJ_01682 2.4e-99 S Pfam:DUF3816
APOGKADJ_01683 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
APOGKADJ_01688 3.5e-96 S Domain of unknown function (DUF2479)
APOGKADJ_01690 1.4e-37
APOGKADJ_01691 7.9e-295 M Prophage endopeptidase tail
APOGKADJ_01692 1e-124 S Phage tail protein
APOGKADJ_01693 6.4e-195 M Phage tail tape measure protein TP901
APOGKADJ_01694 1.6e-59 S Phage tail assembly chaperone proteins, TAC
APOGKADJ_01695 7.8e-134 S Phage tail tube protein
APOGKADJ_01696 3.4e-67 S Protein of unknown function (DUF806)
APOGKADJ_01697 5.5e-71 S Bacteriophage HK97-gp10, putative tail-component
APOGKADJ_01698 2.2e-57 S Phage head-tail joining protein
APOGKADJ_01699 1.3e-42 S Phage gp6-like head-tail connector protein
APOGKADJ_01700 2.4e-175 S Phage capsid family
APOGKADJ_01701 3.9e-67 S Clp protease
APOGKADJ_01702 5.8e-198 S Phage portal protein
APOGKADJ_01704 0.0 S Phage Terminase
APOGKADJ_01705 1.9e-09
APOGKADJ_01707 2.5e-83 L Phage terminase, small subunit
APOGKADJ_01708 1.1e-85 L HNH nucleases
APOGKADJ_01709 1.6e-08
APOGKADJ_01711 4.6e-82 arpU S Phage transcriptional regulator, ArpU family
APOGKADJ_01715 7.3e-70 XK27_00160 S Domain of unknown function (DUF5052)
APOGKADJ_01718 3e-120
APOGKADJ_01719 2.2e-67
APOGKADJ_01721 4.1e-87 L DnaD domain protein
APOGKADJ_01724 8e-15
APOGKADJ_01728 2.8e-10 K Helix-turn-helix XRE-family like proteins
APOGKADJ_01729 6e-80 3.4.21.88 K Peptidase S24-like
APOGKADJ_01730 9.3e-20
APOGKADJ_01731 1.1e-18
APOGKADJ_01733 7e-45
APOGKADJ_01736 3.8e-12 2.1.1.72 V Restriction endonuclease
APOGKADJ_01737 1.7e-207 3.6.4.12 L Belongs to the 'phage' integrase family
APOGKADJ_01738 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APOGKADJ_01739 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APOGKADJ_01740 0.0 dnaK O Heat shock 70 kDa protein
APOGKADJ_01741 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APOGKADJ_01742 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APOGKADJ_01743 5.8e-64
APOGKADJ_01744 2.9e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
APOGKADJ_01745 1.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APOGKADJ_01746 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APOGKADJ_01747 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APOGKADJ_01748 4.5e-49 ylxQ J ribosomal protein
APOGKADJ_01749 1e-44 ylxR K Protein of unknown function (DUF448)
APOGKADJ_01750 1e-215 nusA K Participates in both transcription termination and antitermination
APOGKADJ_01751 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
APOGKADJ_01752 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APOGKADJ_01753 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APOGKADJ_01754 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
APOGKADJ_01755 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
APOGKADJ_01756 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APOGKADJ_01757 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APOGKADJ_01758 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
APOGKADJ_01759 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APOGKADJ_01760 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
APOGKADJ_01761 9.8e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APOGKADJ_01762 5.4e-49 yazA L GIY-YIG catalytic domain protein
APOGKADJ_01763 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
APOGKADJ_01764 4.6e-117 plsC 2.3.1.51 I Acyltransferase
APOGKADJ_01765 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
APOGKADJ_01766 1.3e-35 ynzC S UPF0291 protein
APOGKADJ_01767 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APOGKADJ_01769 2.7e-229 V ATPase associated with various cellular activities
APOGKADJ_01770 2e-45
APOGKADJ_01771 5.7e-17 S Phage gp6-like head-tail connector protein
APOGKADJ_01772 1.2e-190 S Caudovirus prohead serine protease
APOGKADJ_01773 8.9e-140 S Phage portal protein
APOGKADJ_01774 2e-199 terL S overlaps another CDS with the same product name
APOGKADJ_01775 4.1e-25 terS L Phage terminase, small subunit
APOGKADJ_01776 1.7e-76 P FAD-binding domain
APOGKADJ_01777 4.7e-109 S Peptidase propeptide and YPEB domain
APOGKADJ_01778 9.9e-239 T GHKL domain
APOGKADJ_01779 7.3e-121 T Transcriptional regulatory protein, C terminal
APOGKADJ_01780 3.9e-27 mleP3 S Membrane transport protein
APOGKADJ_01781 2.6e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
APOGKADJ_01782 3e-93 dps P Belongs to the Dps family
APOGKADJ_01783 7.9e-35 copZ C Heavy-metal-associated domain
APOGKADJ_01784 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
APOGKADJ_01785 6e-169 L PFAM Integrase catalytic region
APOGKADJ_01786 6.7e-27
APOGKADJ_01787 1.6e-52 azlD S branched-chain amino acid
APOGKADJ_01788 3.7e-136 azlC E AzlC protein
APOGKADJ_01789 4.2e-198 hpk31 2.7.13.3 T Histidine kinase
APOGKADJ_01790 1.2e-123 K response regulator
APOGKADJ_01791 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APOGKADJ_01792 9.5e-112 S Membrane
APOGKADJ_01793 1.2e-64 O Zinc-dependent metalloprotease
APOGKADJ_01794 4.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APOGKADJ_01795 1.2e-157 metQ_4 P Belongs to the nlpA lipoprotein family
APOGKADJ_01797 9.6e-17 NU Mycoplasma protein of unknown function, DUF285
APOGKADJ_01798 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APOGKADJ_01800 2.4e-107 nqr 1.5.1.36 S reductase
APOGKADJ_01801 6.1e-198 XK27_09615 S reductase
APOGKADJ_01802 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APOGKADJ_01803 1.8e-12 S Domain of unknown function (DUF4145)
APOGKADJ_01804 7.4e-19
APOGKADJ_01805 4e-126 S KAP family P-loop domain
APOGKADJ_01806 5.1e-70 L Integrase
APOGKADJ_01808 4e-83 L Integrase
APOGKADJ_01809 1.2e-216 bamA GM domain, Protein
APOGKADJ_01810 1.2e-211 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
APOGKADJ_01811 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APOGKADJ_01816 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APOGKADJ_01817 4.9e-260 yfnA E amino acid
APOGKADJ_01818 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
APOGKADJ_01819 9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APOGKADJ_01820 2e-39 ylqC S Belongs to the UPF0109 family
APOGKADJ_01821 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
APOGKADJ_01822 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APOGKADJ_01823 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APOGKADJ_01824 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APOGKADJ_01825 0.0 smc D Required for chromosome condensation and partitioning
APOGKADJ_01826 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APOGKADJ_01827 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APOGKADJ_01828 1.8e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APOGKADJ_01829 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APOGKADJ_01830 0.0 yloV S DAK2 domain fusion protein YloV
APOGKADJ_01831 4.7e-58 asp S Asp23 family, cell envelope-related function
APOGKADJ_01832 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
APOGKADJ_01833 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
APOGKADJ_01834 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
APOGKADJ_01835 7.5e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APOGKADJ_01836 0.0 KLT serine threonine protein kinase
APOGKADJ_01837 1.1e-130 stp 3.1.3.16 T phosphatase
APOGKADJ_01838 9.6e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APOGKADJ_01839 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APOGKADJ_01840 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APOGKADJ_01841 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APOGKADJ_01842 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APOGKADJ_01843 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
APOGKADJ_01844 1.7e-54
APOGKADJ_01845 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
APOGKADJ_01846 3.3e-77 argR K Regulates arginine biosynthesis genes
APOGKADJ_01847 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
APOGKADJ_01848 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APOGKADJ_01849 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APOGKADJ_01850 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APOGKADJ_01851 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APOGKADJ_01852 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APOGKADJ_01853 2.2e-70 yqhY S Asp23 family, cell envelope-related function
APOGKADJ_01854 1.7e-114 J 2'-5' RNA ligase superfamily
APOGKADJ_01855 7.8e-202 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
APOGKADJ_01856 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APOGKADJ_01857 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
APOGKADJ_01858 1.6e-54 ysxB J Cysteine protease Prp
APOGKADJ_01859 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
APOGKADJ_01860 8.3e-111 K Transcriptional regulator
APOGKADJ_01864 2.5e-89 dut S Protein conserved in bacteria
APOGKADJ_01865 6.6e-174
APOGKADJ_01866 1e-151
APOGKADJ_01867 3.7e-51 S Iron-sulfur cluster assembly protein
APOGKADJ_01868 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APOGKADJ_01869 3.1e-153 P Belongs to the nlpA lipoprotein family
APOGKADJ_01870 3.9e-12
APOGKADJ_01871 4.8e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
APOGKADJ_01872 3.8e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APOGKADJ_01873 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
APOGKADJ_01874 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APOGKADJ_01875 5.9e-22 S Protein of unknown function (DUF3042)
APOGKADJ_01876 3.4e-67 yqhL P Rhodanese-like protein
APOGKADJ_01877 5.6e-183 glk 2.7.1.2 G Glucokinase
APOGKADJ_01878 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
APOGKADJ_01879 3.8e-46 gluP 3.4.21.105 S Peptidase, S54 family
APOGKADJ_01880 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
APOGKADJ_01881 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APOGKADJ_01882 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
APOGKADJ_01883 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
APOGKADJ_01884 0.0 S membrane
APOGKADJ_01885 8.8e-71 yneR S Belongs to the HesB IscA family
APOGKADJ_01886 2e-48 L PFAM transposase IS200-family protein
APOGKADJ_01887 1.3e-73 M PFAM NLP P60 protein
APOGKADJ_01888 2.9e-182 ABC-SBP S ABC transporter
APOGKADJ_01889 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
APOGKADJ_01890 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
APOGKADJ_01892 1.1e-130 arsB 1.20.4.1 P Sodium Bile acid symporter family
APOGKADJ_01893 2.7e-67 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APOGKADJ_01894 3e-18
APOGKADJ_01895 8.2e-52 L Resolvase, N terminal domain
APOGKADJ_01896 1.1e-49
APOGKADJ_01898 1e-196 copB 3.6.3.4 P P-type ATPase
APOGKADJ_01899 1.4e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
APOGKADJ_01900 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
APOGKADJ_01901 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APOGKADJ_01902 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
APOGKADJ_01903 1.7e-11
APOGKADJ_01905 3.8e-47 L Resolvase, N terminal domain
APOGKADJ_01907 5.9e-73 S ECF transporter, substrate-specific component
APOGKADJ_01908 9.8e-51 S Domain of unknown function (DUF4430)
APOGKADJ_01909 4.8e-07 cnrT EG EamA-like transporter family
APOGKADJ_01910 7.4e-230 L transposase, IS605 OrfB family
APOGKADJ_01911 2.1e-60 L PFAM transposase IS200-family protein
APOGKADJ_01912 6.7e-84 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
APOGKADJ_01915 2.6e-155 D CobQ CobB MinD ParA nucleotide binding domain protein
APOGKADJ_01916 1.4e-41
APOGKADJ_01918 2.4e-281 L Transposase IS66 family
APOGKADJ_01919 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
APOGKADJ_01921 1.3e-114 XK27_04590 S NADPH-dependent FMN reductase
APOGKADJ_01922 4.1e-30 fld C Flavodoxin
APOGKADJ_01923 2.8e-170 S AI-2E family transporter
APOGKADJ_01924 8.4e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
APOGKADJ_01925 1.9e-161
APOGKADJ_01927 6e-14 ard S Antirestriction protein (ArdA)
APOGKADJ_01932 1.1e-158 spoU 2.1.1.185 J Methyltransferase
APOGKADJ_01933 4.9e-224 oxlT P Major Facilitator Superfamily
APOGKADJ_01934 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
APOGKADJ_01935 3.3e-46 gcvH E glycine cleavage
APOGKADJ_01936 4.1e-220 rodA D Belongs to the SEDS family
APOGKADJ_01937 1e-31 S Protein of unknown function (DUF2969)
APOGKADJ_01938 1.9e-178 mbl D Cell shape determining protein MreB Mrl
APOGKADJ_01939 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APOGKADJ_01940 1.3e-33 ywzB S Protein of unknown function (DUF1146)
APOGKADJ_01941 4.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
APOGKADJ_01942 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APOGKADJ_01943 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APOGKADJ_01944 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APOGKADJ_01945 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APOGKADJ_01946 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APOGKADJ_01947 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APOGKADJ_01948 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
APOGKADJ_01949 1.5e-231 pyrP F Permease
APOGKADJ_01950 6.3e-129 yibF S overlaps another CDS with the same product name
APOGKADJ_01951 9.9e-192 yibE S overlaps another CDS with the same product name
APOGKADJ_01952 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APOGKADJ_01953 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APOGKADJ_01954 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APOGKADJ_01955 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APOGKADJ_01956 5.7e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APOGKADJ_01957 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APOGKADJ_01958 6e-108 tdk 2.7.1.21 F thymidine kinase
APOGKADJ_01959 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
APOGKADJ_01960 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
APOGKADJ_01961 2.7e-223 arcD U Amino acid permease
APOGKADJ_01962 2.8e-260 E Arginine ornithine antiporter
APOGKADJ_01963 4.7e-79 argR K Regulates arginine biosynthesis genes
APOGKADJ_01964 4.1e-239 arcA 3.5.3.6 E Arginine
APOGKADJ_01965 3.9e-187 ampC V Beta-lactamase
APOGKADJ_01966 1.9e-32
APOGKADJ_01967 0.0 M domain protein
APOGKADJ_01968 2.4e-92
APOGKADJ_01970 1.9e-159 yjcE P Sodium proton antiporter
APOGKADJ_01971 1e-73 yjcE P Sodium proton antiporter
APOGKADJ_01972 5.2e-56
APOGKADJ_01974 4.5e-85
APOGKADJ_01975 0.0 copA 3.6.3.54 P P-type ATPase
APOGKADJ_01976 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
APOGKADJ_01977 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
APOGKADJ_01978 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
APOGKADJ_01979 3.3e-161 EG EamA-like transporter family
APOGKADJ_01980 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
APOGKADJ_01981 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APOGKADJ_01982 8.1e-154 KT YcbB domain
APOGKADJ_01983 1.8e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
APOGKADJ_01984 5.6e-164 xylR GK ROK family
APOGKADJ_01985 1.3e-28
APOGKADJ_01986 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
APOGKADJ_01987 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
APOGKADJ_01988 2.6e-155 glcU U sugar transport
APOGKADJ_01989 2e-272 yclK 2.7.13.3 T Histidine kinase
APOGKADJ_01990 1.5e-132 K response regulator
APOGKADJ_01992 2.8e-79 lytE M Lysin motif
APOGKADJ_01993 2e-149 XK27_02985 S Cof-like hydrolase
APOGKADJ_01994 6.6e-81 K Transcriptional regulator
APOGKADJ_01995 0.0 oatA I Acyltransferase
APOGKADJ_01996 8.7e-53
APOGKADJ_01997 3.3e-83
APOGKADJ_01998 1.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
APOGKADJ_01999 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
APOGKADJ_02000 2.9e-34
APOGKADJ_02001 2.2e-71 D CobQ CobB MinD ParA nucleotide binding domain protein
APOGKADJ_02003 1e-37
APOGKADJ_02004 3.6e-42 S Phage derived protein Gp49-like (DUF891)
APOGKADJ_02005 2.6e-21 K Helix-turn-helix XRE-family like proteins
APOGKADJ_02010 5.7e-21 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
APOGKADJ_02011 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
APOGKADJ_02012 5.5e-45 yitW S Pfam:DUF59
APOGKADJ_02013 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
APOGKADJ_02015 6.8e-50 S Bacterial toxin of type II toxin-antitoxin system, YafQ
APOGKADJ_02016 2.9e-42 relB L RelB antitoxin
APOGKADJ_02017 3.8e-94 L Integrase
APOGKADJ_02019 3.5e-95 L Integrase
APOGKADJ_02020 1.1e-155 S Protein of unknown function DUF262
APOGKADJ_02022 8.4e-28 scrR3 K Transcriptional regulator, LacI family
APOGKADJ_02023 4.2e-224 glpT G Major Facilitator Superfamily
APOGKADJ_02024 3.2e-236 L Integrase core domain
APOGKADJ_02025 3.4e-132 O Bacterial dnaA protein
APOGKADJ_02026 6.7e-114
APOGKADJ_02027 5.2e-156 V ABC transporter, ATP-binding protein
APOGKADJ_02028 9.3e-65 gntR1 K Transcriptional regulator, GntR family
APOGKADJ_02029 1.4e-117 2.1.1.72, 3.1.21.3 V Eco57I restriction-modification methylase
APOGKADJ_02030 1.5e-183 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
APOGKADJ_02031 2.7e-39 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
APOGKADJ_02032 2.5e-155 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
APOGKADJ_02033 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
APOGKADJ_02034 1.1e-90 bioY S BioY family
APOGKADJ_02035 1.5e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APOGKADJ_02036 3.9e-176 phoH T phosphate starvation-inducible protein PhoH
APOGKADJ_02037 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APOGKADJ_02038 9.9e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
APOGKADJ_02039 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APOGKADJ_02040 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
APOGKADJ_02041 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
APOGKADJ_02042 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
APOGKADJ_02043 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APOGKADJ_02044 1.9e-206 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APOGKADJ_02045 1.2e-219 patA 2.6.1.1 E Aminotransferase
APOGKADJ_02046 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
APOGKADJ_02047 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APOGKADJ_02048 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
APOGKADJ_02049 3.1e-30 S Protein of unknown function (DUF2929)
APOGKADJ_02050 0.0 dnaE 2.7.7.7 L DNA polymerase
APOGKADJ_02051 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
APOGKADJ_02052 2.3e-167 cvfB S S1 domain
APOGKADJ_02053 1.2e-163 xerD D recombinase XerD
APOGKADJ_02054 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APOGKADJ_02055 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APOGKADJ_02056 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APOGKADJ_02057 1.1e-127 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APOGKADJ_02058 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APOGKADJ_02059 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
APOGKADJ_02060 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
APOGKADJ_02061 8.5e-14 M Lysin motif
APOGKADJ_02062 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
APOGKADJ_02063 2.5e-204 rpsA 1.17.7.4 J Ribosomal protein S1
APOGKADJ_02064 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
APOGKADJ_02065 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APOGKADJ_02066 1.5e-236 S Tetratricopeptide repeat protein
APOGKADJ_02067 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APOGKADJ_02068 0.0 yfmR S ABC transporter, ATP-binding protein
APOGKADJ_02069 7.7e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APOGKADJ_02070 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APOGKADJ_02071 5.3e-113 hlyIII S protein, hemolysin III
APOGKADJ_02072 1.7e-151 DegV S EDD domain protein, DegV family
APOGKADJ_02073 9.5e-172 ypmR E lipolytic protein G-D-S-L family
APOGKADJ_02074 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
APOGKADJ_02075 4.4e-35 yozE S Belongs to the UPF0346 family
APOGKADJ_02076 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APOGKADJ_02077 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APOGKADJ_02078 2.4e-161 dprA LU DNA protecting protein DprA
APOGKADJ_02079 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APOGKADJ_02080 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
APOGKADJ_02081 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APOGKADJ_02082 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APOGKADJ_02083 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APOGKADJ_02084 1.7e-84 F NUDIX domain
APOGKADJ_02085 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
APOGKADJ_02086 3.6e-07 S Helix-turn-helix domain
APOGKADJ_02089 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
APOGKADJ_02090 8.3e-67 V Type II restriction enzyme, methylase subunits
APOGKADJ_02091 1.2e-77 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
APOGKADJ_02092 1.1e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
APOGKADJ_02093 6.6e-262 S Putative peptidoglycan binding domain
APOGKADJ_02094 1.4e-191 2.7.7.6 M Peptidase family M23
APOGKADJ_02095 2.1e-73 K Copper transport repressor CopY TcrY
APOGKADJ_02096 2e-39 ycfA K Bacterial regulatory proteins, tetR family
APOGKADJ_02115 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APOGKADJ_02116 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APOGKADJ_02117 2e-126 ybbR S YbbR-like protein
APOGKADJ_02118 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APOGKADJ_02119 6.1e-244 fucP G Major Facilitator Superfamily
APOGKADJ_02120 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
APOGKADJ_02121 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APOGKADJ_02122 3.6e-168 murB 1.3.1.98 M Cell wall formation
APOGKADJ_02123 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
APOGKADJ_02124 4.4e-76 S PAS domain
APOGKADJ_02125 2.6e-86 K Acetyltransferase (GNAT) domain
APOGKADJ_02126 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
APOGKADJ_02127 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
APOGKADJ_02128 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APOGKADJ_02129 6.3e-105 yxjI
APOGKADJ_02130 4.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
APOGKADJ_02131 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APOGKADJ_02132 7.5e-146 est 3.1.1.1 S Serine aminopeptidase, S33
APOGKADJ_02133 1.8e-34 secG U Preprotein translocase
APOGKADJ_02134 4e-292 clcA P chloride
APOGKADJ_02135 7.1e-248 yifK E Amino acid permease
APOGKADJ_02136 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APOGKADJ_02137 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APOGKADJ_02138 3.2e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
APOGKADJ_02139 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APOGKADJ_02141 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APOGKADJ_02142 8.8e-15
APOGKADJ_02144 4e-170 whiA K May be required for sporulation
APOGKADJ_02145 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
APOGKADJ_02146 3.2e-161 rapZ S Displays ATPase and GTPase activities
APOGKADJ_02147 5.4e-245 steT E amino acid
APOGKADJ_02148 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APOGKADJ_02149 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APOGKADJ_02150 1.5e-13
APOGKADJ_02151 2.3e-116 yfbR S HD containing hydrolase-like enzyme
APOGKADJ_02152 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
APOGKADJ_02153 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
APOGKADJ_02154 3.5e-103 aatB ET PFAM extracellular solute-binding protein, family 3
APOGKADJ_02155 5.9e-32 aatB ET PFAM extracellular solute-binding protein, family 3
APOGKADJ_02156 1.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
APOGKADJ_02157 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APOGKADJ_02158 3.5e-163 lutA C Cysteine-rich domain
APOGKADJ_02159 7.5e-288 lutB C 4Fe-4S dicluster domain
APOGKADJ_02160 3.9e-136 yrjD S LUD domain
APOGKADJ_02161 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APOGKADJ_02162 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
APOGKADJ_02163 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APOGKADJ_02164 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APOGKADJ_02165 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
APOGKADJ_02166 3.1e-32 KT PspC domain protein
APOGKADJ_02167 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APOGKADJ_02168 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)