ORF_ID e_value Gene_name EC_number CAZy COGs Description
HBOPLIAO_00002 1.4e-41
HBOPLIAO_00003 2.6e-155 D CobQ CobB MinD ParA nucleotide binding domain protein
HBOPLIAO_00007 2.1e-11
HBOPLIAO_00009 3.8e-47 L Resolvase, N terminal domain
HBOPLIAO_00010 1.3e-150 2.1.1.72, 3.1.21.3 V N-6 DNA Methylase
HBOPLIAO_00011 3.4e-170 gntT EG Gluconate
HBOPLIAO_00012 2.9e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HBOPLIAO_00013 2.9e-96 K Acetyltransferase (GNAT) domain
HBOPLIAO_00014 5.4e-47
HBOPLIAO_00017 1.3e-18
HBOPLIAO_00018 2.8e-81 S KNTase C-terminal domain
HBOPLIAO_00019 4e-113 yjbH Q Thioredoxin
HBOPLIAO_00020 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
HBOPLIAO_00021 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBOPLIAO_00022 7.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HBOPLIAO_00023 7.3e-193 L Transposase IS66 family
HBOPLIAO_00024 9.9e-61 XK27_01125 L PFAM IS66 Orf2 family protein
HBOPLIAO_00027 8.1e-47 XK27_01125 L PFAM IS66 Orf2 family protein
HBOPLIAO_00028 1.6e-34 L Transposase IS66 family
HBOPLIAO_00029 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HBOPLIAO_00030 6.7e-93 dps P Belongs to the Dps family
HBOPLIAO_00031 7.9e-35 copZ C Heavy-metal-associated domain
HBOPLIAO_00032 4.1e-201 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HBOPLIAO_00033 7.4e-110 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HBOPLIAO_00034 1.2e-78 2.7.13.3 T GHKL domain
HBOPLIAO_00037 3.7e-260 S Putative peptidoglycan binding domain
HBOPLIAO_00038 3.5e-35
HBOPLIAO_00039 2.3e-228 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HBOPLIAO_00040 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HBOPLIAO_00041 1.2e-216 bamA GM domain, Protein
HBOPLIAO_00042 4e-83 L Integrase
HBOPLIAO_00048 1.7e-243 V Type II restriction enzyme, methylase subunits
HBOPLIAO_00050 8.4e-28 scrR3 K Transcriptional regulator, LacI family
HBOPLIAO_00051 4.2e-224 glpT G Major Facilitator Superfamily
HBOPLIAO_00054 1.6e-106 L Belongs to the 'phage' integrase family
HBOPLIAO_00056 5.7e-21 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HBOPLIAO_00061 2.6e-21 K Helix-turn-helix XRE-family like proteins
HBOPLIAO_00062 3.6e-42 S Phage derived protein Gp49-like (DUF891)
HBOPLIAO_00070 3.3e-14 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HBOPLIAO_00072 2.2e-22
HBOPLIAO_00080 6e-14 ard S Antirestriction protein (ArdA)
HBOPLIAO_00084 1e-37
HBOPLIAO_00086 2.2e-71 D CobQ CobB MinD ParA nucleotide binding domain protein
HBOPLIAO_00087 2.8e-13 S Replication initiator protein A (RepA) N-terminus
HBOPLIAO_00090 6.6e-09 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HBOPLIAO_00091 2.2e-93 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HBOPLIAO_00092 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HBOPLIAO_00093 3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HBOPLIAO_00094 1.6e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HBOPLIAO_00095 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HBOPLIAO_00096 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
HBOPLIAO_00097 7.1e-101 ydaM M Glycosyl transferase family group 2
HBOPLIAO_00098 3.4e-224 G Glycosyl hydrolases family 8
HBOPLIAO_00099 1.3e-122 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HBOPLIAO_00100 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBOPLIAO_00101 5.5e-45 yitW S Pfam:DUF59
HBOPLIAO_00102 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HBOPLIAO_00103 0.0 lacS G Transporter
HBOPLIAO_00110 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
HBOPLIAO_00111 2.4e-281 L Transposase IS66 family
HBOPLIAO_00112 1.6e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HBOPLIAO_00133 1.2e-37 azlC E azaleucine resistance protein AzlC
HBOPLIAO_00134 7.3e-60 K Aminotransferase class I and II
HBOPLIAO_00135 2e-152 K Aminotransferase class I and II
HBOPLIAO_00136 3.6e-288 S amidohydrolase
HBOPLIAO_00138 1.8e-161 S reductase
HBOPLIAO_00139 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
HBOPLIAO_00140 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HBOPLIAO_00141 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
HBOPLIAO_00142 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBOPLIAO_00143 0.0 asnB 6.3.5.4 E Asparagine synthase
HBOPLIAO_00144 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HBOPLIAO_00145 4.3e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HBOPLIAO_00146 9.7e-130 jag S R3H domain protein
HBOPLIAO_00147 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HBOPLIAO_00148 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HBOPLIAO_00149 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HBOPLIAO_00150 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HBOPLIAO_00151 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HBOPLIAO_00152 3.3e-82 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HBOPLIAO_00153 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HBOPLIAO_00154 1.7e-34 yaaA S S4 domain protein YaaA
HBOPLIAO_00155 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HBOPLIAO_00156 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBOPLIAO_00157 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HBOPLIAO_00158 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HBOPLIAO_00159 1.4e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HBOPLIAO_00160 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HBOPLIAO_00161 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HBOPLIAO_00162 2e-74 rplI J Binds to the 23S rRNA
HBOPLIAO_00163 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HBOPLIAO_00164 1.3e-205 yttB EGP Major facilitator Superfamily
HBOPLIAO_00165 3.7e-54
HBOPLIAO_00166 2e-155 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HBOPLIAO_00167 3.7e-08 K DNA-binding helix-turn-helix protein
HBOPLIAO_00168 9e-125 O Bacterial dnaA protein
HBOPLIAO_00169 3.5e-214 L Integrase core domain
HBOPLIAO_00172 3.2e-236 L Integrase core domain
HBOPLIAO_00173 3.4e-132 O Bacterial dnaA protein
HBOPLIAO_00174 5.7e-172
HBOPLIAO_00175 1.1e-72
HBOPLIAO_00176 1.9e-46 L Transposase
HBOPLIAO_00177 3.4e-171 L Integrase core domain
HBOPLIAO_00179 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
HBOPLIAO_00180 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HBOPLIAO_00181 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBOPLIAO_00183 2.1e-41 ybaN S Protein of unknown function (DUF454)
HBOPLIAO_00184 3.1e-72 S Protein of unknown function (DUF3290)
HBOPLIAO_00185 6.2e-114 yviA S Protein of unknown function (DUF421)
HBOPLIAO_00186 1.5e-36 sugE U Multidrug resistance protein
HBOPLIAO_00187 3e-23
HBOPLIAO_00188 5.6e-261 S Uncharacterised protein family (UPF0236)
HBOPLIAO_00189 1.4e-47 yktA S Belongs to the UPF0223 family
HBOPLIAO_00190 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HBOPLIAO_00191 0.0 typA T GTP-binding protein TypA
HBOPLIAO_00192 2e-222 ftsW D Belongs to the SEDS family
HBOPLIAO_00193 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HBOPLIAO_00194 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HBOPLIAO_00195 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HBOPLIAO_00196 3.3e-197 ylbL T Belongs to the peptidase S16 family
HBOPLIAO_00197 2.6e-80 comEA L Competence protein ComEA
HBOPLIAO_00198 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
HBOPLIAO_00199 0.0 comEC S Competence protein ComEC
HBOPLIAO_00200 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
HBOPLIAO_00201 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HBOPLIAO_00202 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HBOPLIAO_00203 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBOPLIAO_00204 1.3e-162 S Tetratricopeptide repeat
HBOPLIAO_00205 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HBOPLIAO_00206 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HBOPLIAO_00207 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HBOPLIAO_00208 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HBOPLIAO_00209 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HBOPLIAO_00210 1.3e-08
HBOPLIAO_00211 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HBOPLIAO_00212 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HBOPLIAO_00213 1.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HBOPLIAO_00214 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HBOPLIAO_00215 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HBOPLIAO_00216 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HBOPLIAO_00217 2.1e-87
HBOPLIAO_00218 4.1e-134 L Belongs to the 'phage' integrase family
HBOPLIAO_00219 3.6e-35 S Domain of unknown function (DUF5067)
HBOPLIAO_00220 3.8e-10 K sequence-specific DNA binding
HBOPLIAO_00221 1.6e-14 S Helix-turn-helix domain
HBOPLIAO_00222 1.8e-41 S Phage regulatory protein Rha (Phage_pRha)
HBOPLIAO_00225 9.3e-08
HBOPLIAO_00228 4.5e-56 S DNA primase
HBOPLIAO_00229 1.4e-14
HBOPLIAO_00230 4.9e-265 L PFAM Integrase catalytic region
HBOPLIAO_00231 2.8e-162 yueF S AI-2E family transporter
HBOPLIAO_00232 2.1e-126
HBOPLIAO_00233 3.6e-54 S Sugar efflux transporter for intercellular exchange
HBOPLIAO_00234 6.6e-218 L Transposase
HBOPLIAO_00235 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HBOPLIAO_00236 1.9e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HBOPLIAO_00237 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HBOPLIAO_00238 6.1e-32 ant 2.7.7.47 S Domain of unknown function (DUF4111)
HBOPLIAO_00239 3.8e-64 ant 2.7.7.47 S Domain of unknown function (DUF4111)
HBOPLIAO_00240 9.2e-178 L PFAM Integrase catalytic region
HBOPLIAO_00241 1.3e-114 XK27_04590 S NADPH-dependent FMN reductase
HBOPLIAO_00242 1.1e-72 fld C Flavodoxin
HBOPLIAO_00243 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
HBOPLIAO_00244 5.9e-68 P Cadmium resistance transporter
HBOPLIAO_00245 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
HBOPLIAO_00246 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
HBOPLIAO_00247 3e-54 pduU E BMC
HBOPLIAO_00248 1.1e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBOPLIAO_00249 4.3e-203 pduQ C Iron-containing alcohol dehydrogenase
HBOPLIAO_00250 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HBOPLIAO_00251 1.1e-78 pduO S Haem-degrading
HBOPLIAO_00252 7e-104 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HBOPLIAO_00253 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HBOPLIAO_00254 1.3e-79 S Putative propanediol utilisation
HBOPLIAO_00255 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HBOPLIAO_00256 7.8e-40 pduA_4 CQ BMC
HBOPLIAO_00257 3.6e-57 pduK CQ BMC
HBOPLIAO_00258 8.1e-45 pduH S Dehydratase medium subunit
HBOPLIAO_00259 3.1e-307 pduG D Diol dehydratase reactivase ATPase-like domain
HBOPLIAO_00260 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
HBOPLIAO_00261 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HBOPLIAO_00262 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HBOPLIAO_00263 2.7e-134 pduB E BMC
HBOPLIAO_00264 1.6e-37 pduA_4 CQ BMC
HBOPLIAO_00265 8.3e-159 K helix_turn_helix, arabinose operon control protein
HBOPLIAO_00266 3.6e-138 eutJ E Hsp70 protein
HBOPLIAO_00267 1.9e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HBOPLIAO_00268 3.2e-95
HBOPLIAO_00269 6.4e-127 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HBOPLIAO_00270 5.9e-152 S AI-2E family transporter
HBOPLIAO_00271 5.2e-133 XK27_07210 6.1.1.6 S B3 4 domain
HBOPLIAO_00272 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
HBOPLIAO_00273 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
HBOPLIAO_00274 4.8e-88 GM epimerase
HBOPLIAO_00275 1.7e-154 ypdB V (ABC) transporter
HBOPLIAO_00276 6.8e-240 yhdP S Transporter associated domain
HBOPLIAO_00277 9.9e-85 nrdI F Belongs to the NrdI family
HBOPLIAO_00278 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
HBOPLIAO_00279 3.1e-193 yeaN P Transporter, major facilitator family protein
HBOPLIAO_00280 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HBOPLIAO_00281 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HBOPLIAO_00282 2.9e-139 csd1 3.5.1.28 G domain, Protein
HBOPLIAO_00283 5.8e-39 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBOPLIAO_00284 4e-28 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HBOPLIAO_00289 6e-97 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HBOPLIAO_00290 2.4e-289 clcA P chloride
HBOPLIAO_00291 1.8e-34 secG U Preprotein translocase
HBOPLIAO_00292 5.7e-146 est 3.1.1.1 S Serine aminopeptidase, S33
HBOPLIAO_00293 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HBOPLIAO_00294 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HBOPLIAO_00295 6.3e-105 yxjI
HBOPLIAO_00296 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HBOPLIAO_00297 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HBOPLIAO_00298 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HBOPLIAO_00299 7.4e-86 K Acetyltransferase (GNAT) domain
HBOPLIAO_00300 4.4e-76 S PAS domain
HBOPLIAO_00301 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
HBOPLIAO_00302 1.6e-168 murB 1.3.1.98 M Cell wall formation
HBOPLIAO_00303 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBOPLIAO_00304 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HBOPLIAO_00305 4.8e-249 fucP G Major Facilitator Superfamily
HBOPLIAO_00306 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HBOPLIAO_00307 2e-126 ybbR S YbbR-like protein
HBOPLIAO_00308 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBOPLIAO_00309 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HBOPLIAO_00310 8.7e-53
HBOPLIAO_00311 0.0 oatA I Acyltransferase
HBOPLIAO_00312 2.3e-81 K Transcriptional regulator
HBOPLIAO_00313 2e-149 XK27_02985 S Cof-like hydrolase
HBOPLIAO_00314 2.8e-79 lytE M Lysin motif
HBOPLIAO_00316 5.7e-132 K response regulator
HBOPLIAO_00317 2.6e-272 yclK 2.7.13.3 T Histidine kinase
HBOPLIAO_00318 2.6e-155 glcU U sugar transport
HBOPLIAO_00319 1.3e-92 lacA 2.3.1.79 S Transferase hexapeptide repeat
HBOPLIAO_00320 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
HBOPLIAO_00321 1.3e-28
HBOPLIAO_00322 1.6e-216 xylR GK ROK family
HBOPLIAO_00324 1.3e-260 xylT EGP Major facilitator Superfamily
HBOPLIAO_00325 4.5e-89 rhaS2 K Transcriptional regulator, AraC family
HBOPLIAO_00326 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBOPLIAO_00327 9.7e-173
HBOPLIAO_00328 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBOPLIAO_00329 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
HBOPLIAO_00330 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HBOPLIAO_00331 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBOPLIAO_00332 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HBOPLIAO_00333 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HBOPLIAO_00334 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBOPLIAO_00335 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBOPLIAO_00336 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBOPLIAO_00337 5.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HBOPLIAO_00338 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBOPLIAO_00339 4.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBOPLIAO_00340 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HBOPLIAO_00341 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HBOPLIAO_00342 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HBOPLIAO_00343 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HBOPLIAO_00344 4.9e-177 K AI-2E family transporter
HBOPLIAO_00345 4.2e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HBOPLIAO_00346 6.7e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBOPLIAO_00347 9.6e-115 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HBOPLIAO_00348 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HBOPLIAO_00349 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HBOPLIAO_00350 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HBOPLIAO_00351 3.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HBOPLIAO_00352 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HBOPLIAO_00353 1.7e-130 K LysR substrate binding domain
HBOPLIAO_00355 9.1e-75 M PFAM NLP P60 protein
HBOPLIAO_00356 2.2e-182 ABC-SBP S ABC transporter
HBOPLIAO_00357 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HBOPLIAO_00358 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
HBOPLIAO_00359 4.5e-92 P Cadmium resistance transporter
HBOPLIAO_00360 6.8e-56 K Transcriptional regulator, ArsR family
HBOPLIAO_00361 5.5e-55 M Leucine-rich repeat (LRR) protein
HBOPLIAO_00362 1.6e-236 mepA V MATE efflux family protein
HBOPLIAO_00363 2.1e-54 trxA O Belongs to the thioredoxin family
HBOPLIAO_00364 5.6e-130 terC P membrane
HBOPLIAO_00365 1.3e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HBOPLIAO_00366 2.2e-168 corA P CorA-like Mg2+ transporter protein
HBOPLIAO_00367 1.6e-305 L Transposase
HBOPLIAO_00368 1.4e-283 pipD E Dipeptidase
HBOPLIAO_00369 1.6e-241 pbuX F xanthine permease
HBOPLIAO_00370 1.8e-251 nhaC C Na H antiporter NhaC
HBOPLIAO_00371 4e-240 S C4-dicarboxylate anaerobic carrier
HBOPLIAO_00372 1.1e-27 S C4-dicarboxylate anaerobic carrier
HBOPLIAO_00373 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
HBOPLIAO_00374 1.3e-41
HBOPLIAO_00375 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HBOPLIAO_00376 3.8e-207 gldA 1.1.1.6 C dehydrogenase
HBOPLIAO_00377 5.5e-126 S Alpha beta hydrolase
HBOPLIAO_00378 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HBOPLIAO_00379 2.5e-101
HBOPLIAO_00381 1.4e-124 yciB M ErfK YbiS YcfS YnhG
HBOPLIAO_00382 4.3e-86 uspA T Belongs to the universal stress protein A family
HBOPLIAO_00383 2.1e-276 pepV 3.5.1.18 E dipeptidase PepV
HBOPLIAO_00384 6.5e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBOPLIAO_00385 4.1e-303 ytgP S Polysaccharide biosynthesis protein
HBOPLIAO_00386 4.9e-41
HBOPLIAO_00387 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HBOPLIAO_00388 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HBOPLIAO_00389 9.6e-92 tag 3.2.2.20 L glycosylase
HBOPLIAO_00390 1.5e-253 EGP Major facilitator Superfamily
HBOPLIAO_00391 4.3e-85 perR P Belongs to the Fur family
HBOPLIAO_00392 6.3e-233 cycA E Amino acid permease
HBOPLIAO_00393 2.8e-102 V VanZ like family
HBOPLIAO_00394 1e-23
HBOPLIAO_00395 6.7e-82 S Short repeat of unknown function (DUF308)
HBOPLIAO_00396 2.9e-78 S Psort location Cytoplasmic, score
HBOPLIAO_00397 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HBOPLIAO_00398 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HBOPLIAO_00399 8.1e-154 yeaE S Aldo keto
HBOPLIAO_00400 2.3e-93 lytE M LysM domain protein
HBOPLIAO_00401 0.0 oppD EP Psort location Cytoplasmic, score
HBOPLIAO_00402 3.3e-80 lytE M LysM domain protein
HBOPLIAO_00403 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
HBOPLIAO_00404 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HBOPLIAO_00405 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HBOPLIAO_00406 1.5e-237 lmrB EGP Major facilitator Superfamily
HBOPLIAO_00407 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
HBOPLIAO_00417 2.9e-15
HBOPLIAO_00418 1.1e-119 ybhL S Belongs to the BI1 family
HBOPLIAO_00419 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HBOPLIAO_00420 9.3e-197 S Protein of unknown function (DUF3114)
HBOPLIAO_00421 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HBOPLIAO_00422 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HBOPLIAO_00423 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HBOPLIAO_00424 9.1e-62 S Domain of unknown function (DUF4828)
HBOPLIAO_00425 4.5e-191 mocA S Oxidoreductase
HBOPLIAO_00426 8.5e-227 yfmL L DEAD DEAH box helicase
HBOPLIAO_00428 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HBOPLIAO_00429 9.3e-56
HBOPLIAO_00430 2.3e-67 gtcA S Teichoic acid glycosylation protein
HBOPLIAO_00431 8.8e-78 fld C Flavodoxin
HBOPLIAO_00432 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
HBOPLIAO_00433 1.7e-220 arcT 2.6.1.1 E Aminotransferase
HBOPLIAO_00434 3.6e-255 E Arginine ornithine antiporter
HBOPLIAO_00435 4.1e-281 yjeM E Amino Acid
HBOPLIAO_00436 3.2e-153 yihY S Belongs to the UPF0761 family
HBOPLIAO_00437 6.6e-34 S Protein of unknown function (DUF2922)
HBOPLIAO_00438 4.9e-31
HBOPLIAO_00439 7.4e-125 recX 2.4.1.337 GT4 S Regulatory protein RecX
HBOPLIAO_00440 3.3e-146 cps1D M Domain of unknown function (DUF4422)
HBOPLIAO_00441 8.3e-176 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HBOPLIAO_00442 5.9e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
HBOPLIAO_00443 0.0 2.7.7.6 M Peptidase family M23
HBOPLIAO_00444 0.0 G Peptidase_C39 like family
HBOPLIAO_00445 2.1e-25
HBOPLIAO_00446 1.7e-145 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HBOPLIAO_00447 1.1e-63 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HBOPLIAO_00448 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
HBOPLIAO_00449 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HBOPLIAO_00450 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
HBOPLIAO_00451 1.1e-239 hemL 5.4.3.8 H Aminotransferase class-III
HBOPLIAO_00452 6.2e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
HBOPLIAO_00453 3.4e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HBOPLIAO_00454 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HBOPLIAO_00455 6e-58 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
HBOPLIAO_00456 1.3e-239 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HBOPLIAO_00457 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
HBOPLIAO_00458 3.4e-102 cbiQ P Cobalt transport protein
HBOPLIAO_00459 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HBOPLIAO_00460 1.9e-122 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HBOPLIAO_00461 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HBOPLIAO_00462 8.1e-108 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
HBOPLIAO_00463 3.3e-176 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HBOPLIAO_00464 2.8e-97 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
HBOPLIAO_00465 6.6e-128 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HBOPLIAO_00466 1.1e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
HBOPLIAO_00467 1.4e-128 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HBOPLIAO_00468 4.5e-70 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HBOPLIAO_00469 3.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HBOPLIAO_00470 1.7e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HBOPLIAO_00471 9.3e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
HBOPLIAO_00472 1.6e-145 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HBOPLIAO_00473 4.3e-205 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HBOPLIAO_00474 4.7e-170 cobD 4.1.1.81 E Aminotransferase class I and II
HBOPLIAO_00475 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
HBOPLIAO_00476 1.2e-114 rlpA M PFAM NLP P60 protein
HBOPLIAO_00477 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HBOPLIAO_00478 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HBOPLIAO_00479 2.6e-58 yodB K Transcriptional regulator, HxlR family
HBOPLIAO_00480 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HBOPLIAO_00481 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBOPLIAO_00482 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HBOPLIAO_00483 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HBOPLIAO_00484 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HBOPLIAO_00485 4.4e-231 V MatE
HBOPLIAO_00486 7.4e-267 yjeM E Amino Acid
HBOPLIAO_00487 1.6e-277 arlS 2.7.13.3 T Histidine kinase
HBOPLIAO_00488 1.5e-121 K response regulator
HBOPLIAO_00489 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HBOPLIAO_00490 9.3e-98 yceD S Uncharacterized ACR, COG1399
HBOPLIAO_00491 4.6e-213 ylbM S Belongs to the UPF0348 family
HBOPLIAO_00492 1.7e-139 yqeM Q Methyltransferase
HBOPLIAO_00493 6.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HBOPLIAO_00494 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HBOPLIAO_00495 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HBOPLIAO_00496 1.9e-47 yhbY J RNA-binding protein
HBOPLIAO_00497 1.4e-217 yqeH S Ribosome biogenesis GTPase YqeH
HBOPLIAO_00498 1.8e-95 yqeG S HAD phosphatase, family IIIA
HBOPLIAO_00499 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HBOPLIAO_00500 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HBOPLIAO_00501 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HBOPLIAO_00502 1.1e-170 dnaI L Primosomal protein DnaI
HBOPLIAO_00503 1.4e-203 dnaB L replication initiation and membrane attachment
HBOPLIAO_00504 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HBOPLIAO_00505 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBOPLIAO_00506 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HBOPLIAO_00507 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HBOPLIAO_00508 2e-115 yoaK S Protein of unknown function (DUF1275)
HBOPLIAO_00509 1.9e-119 ybhL S Belongs to the BI1 family
HBOPLIAO_00510 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HBOPLIAO_00511 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HBOPLIAO_00512 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HBOPLIAO_00513 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HBOPLIAO_00514 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HBOPLIAO_00515 7.5e-58 ytzB S Small secreted protein
HBOPLIAO_00516 1.2e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
HBOPLIAO_00517 8.8e-184 iolS C Aldo keto reductase
HBOPLIAO_00518 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HBOPLIAO_00519 2.3e-145 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HBOPLIAO_00520 9.5e-256 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HBOPLIAO_00521 2.5e-35 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HBOPLIAO_00522 7.7e-27 S YSIRK type signal peptide
HBOPLIAO_00523 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HBOPLIAO_00524 5.1e-218 ecsB U ABC transporter
HBOPLIAO_00525 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HBOPLIAO_00526 1.2e-76 hit FG histidine triad
HBOPLIAO_00528 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HBOPLIAO_00529 0.0 L AAA domain
HBOPLIAO_00530 1.8e-220 yhaO L Ser Thr phosphatase family protein
HBOPLIAO_00531 3.5e-40 yheA S Belongs to the UPF0342 family
HBOPLIAO_00532 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HBOPLIAO_00533 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HBOPLIAO_00534 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HBOPLIAO_00535 1e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HBOPLIAO_00537 1.2e-32
HBOPLIAO_00538 1.8e-43
HBOPLIAO_00539 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
HBOPLIAO_00540 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HBOPLIAO_00541 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HBOPLIAO_00542 4e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HBOPLIAO_00543 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HBOPLIAO_00544 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HBOPLIAO_00545 5.4e-68
HBOPLIAO_00548 5.6e-155 lysA2 M Glycosyl hydrolases family 25
HBOPLIAO_00549 1.8e-39 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HBOPLIAO_00556 2.1e-44 GT2,GT4 LM gp58-like protein
HBOPLIAO_00557 1.1e-140 ydhO 3.4.14.13 M Prophage endopeptidase tail
HBOPLIAO_00558 1e-82 S Phage tail protein
HBOPLIAO_00559 5.2e-263 M Phage tail tape measure protein TP901
HBOPLIAO_00560 9.6e-08 S Phage tail assembly chaperone proteins, TAC
HBOPLIAO_00561 1.6e-77 S Phage tail tube protein
HBOPLIAO_00562 4.9e-18 S Protein of unknown function (DUF806)
HBOPLIAO_00563 2.6e-31 S exonuclease activity
HBOPLIAO_00564 1.8e-09 S Phage head-tail joining protein
HBOPLIAO_00565 1.1e-40 S Phage gp6-like head-tail connector protein
HBOPLIAO_00566 8.1e-152 S Phage capsid family
HBOPLIAO_00567 6.3e-107 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HBOPLIAO_00568 1.3e-210 S Phage portal protein
HBOPLIAO_00569 1.8e-286 S overlaps another CDS with the same product name
HBOPLIAO_00570 1.9e-64 L Phage terminase, small subunit
HBOPLIAO_00571 1.4e-55 L HNH nucleases
HBOPLIAO_00574 1.7e-75
HBOPLIAO_00577 3.5e-20
HBOPLIAO_00579 2e-08 K Helix-turn-helix XRE-family like proteins
HBOPLIAO_00580 2.9e-53 S Protein of unknown function (DUF1064)
HBOPLIAO_00582 2.9e-44 dnaC 3.4.21.53 L IstB-like ATP binding protein
HBOPLIAO_00583 9.4e-30 ybl78 L DnaD domain protein
HBOPLIAO_00584 1.5e-14 L Single-strand binding protein family
HBOPLIAO_00585 2.7e-51 S ERF superfamily
HBOPLIAO_00590 1.8e-11 S Domain of unknown function (DUF771)
HBOPLIAO_00591 3.1e-120 K BRO family, N-terminal domain
HBOPLIAO_00593 4.5e-23 S sequence-specific DNA binding
HBOPLIAO_00595 9.5e-20
HBOPLIAO_00596 2.2e-73 S Domain of unknown function (DUF4393)
HBOPLIAO_00598 9e-105 L Belongs to the 'phage' integrase family
HBOPLIAO_00600 1.9e-43
HBOPLIAO_00601 2.6e-118 S CAAX protease self-immunity
HBOPLIAO_00602 2.1e-32
HBOPLIAO_00603 7.5e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBOPLIAO_00604 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HBOPLIAO_00605 8.5e-113
HBOPLIAO_00606 1.1e-115 dck 2.7.1.74 F deoxynucleoside kinase
HBOPLIAO_00607 9.2e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBOPLIAO_00608 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBOPLIAO_00609 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HBOPLIAO_00610 2.6e-149 purR 2.4.2.7 F pur operon repressor
HBOPLIAO_00611 1.4e-118 znuB U ABC 3 transport family
HBOPLIAO_00612 5.5e-121 fhuC P ABC transporter
HBOPLIAO_00613 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
HBOPLIAO_00614 9.2e-40
HBOPLIAO_00615 0.0 ydaO E amino acid
HBOPLIAO_00616 4.3e-305 ybeC E amino acid
HBOPLIAO_00617 8.2e-82 S YbaK proline--tRNA ligase associated domain protein
HBOPLIAO_00618 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HBOPLIAO_00619 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HBOPLIAO_00621 3.1e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HBOPLIAO_00622 0.0 uup S ABC transporter, ATP-binding protein
HBOPLIAO_00623 4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBOPLIAO_00624 4.2e-225 mtnE 2.6.1.83 E Aminotransferase
HBOPLIAO_00625 6.6e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HBOPLIAO_00626 1.2e-135 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HBOPLIAO_00627 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HBOPLIAO_00628 4.7e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBOPLIAO_00629 2.5e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HBOPLIAO_00630 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HBOPLIAO_00631 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HBOPLIAO_00632 1.7e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HBOPLIAO_00633 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HBOPLIAO_00634 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HBOPLIAO_00635 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HBOPLIAO_00636 4.5e-49 ylxQ J ribosomal protein
HBOPLIAO_00637 1e-44 ylxR K Protein of unknown function (DUF448)
HBOPLIAO_00638 1e-215 nusA K Participates in both transcription termination and antitermination
HBOPLIAO_00639 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HBOPLIAO_00640 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBOPLIAO_00641 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HBOPLIAO_00642 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HBOPLIAO_00643 1.7e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HBOPLIAO_00644 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HBOPLIAO_00645 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HBOPLIAO_00646 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HBOPLIAO_00647 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HBOPLIAO_00648 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HBOPLIAO_00649 2.8e-182 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBOPLIAO_00650 5.4e-49 yazA L GIY-YIG catalytic domain protein
HBOPLIAO_00651 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
HBOPLIAO_00652 4.6e-117 plsC 2.3.1.51 I Acyltransferase
HBOPLIAO_00653 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HBOPLIAO_00654 1.3e-35 ynzC S UPF0291 protein
HBOPLIAO_00655 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBOPLIAO_00656 2.3e-110 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HBOPLIAO_00657 5.8e-64
HBOPLIAO_00658 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HBOPLIAO_00659 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HBOPLIAO_00660 0.0 dnaK O Heat shock 70 kDa protein
HBOPLIAO_00661 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HBOPLIAO_00662 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HBOPLIAO_00663 4.1e-275 pipD E Dipeptidase
HBOPLIAO_00664 4e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HBOPLIAO_00666 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HBOPLIAO_00668 2.8e-57
HBOPLIAO_00669 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
HBOPLIAO_00670 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HBOPLIAO_00671 1.2e-52
HBOPLIAO_00672 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBOPLIAO_00673 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HBOPLIAO_00674 1.4e-118 yniA G Phosphotransferase enzyme family
HBOPLIAO_00675 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HBOPLIAO_00676 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HBOPLIAO_00677 5.9e-264 glnPH2 P ABC transporter permease
HBOPLIAO_00678 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HBOPLIAO_00679 3.8e-70 yqeY S YqeY-like protein
HBOPLIAO_00680 3.7e-56 ltrA S Bacterial low temperature requirement A protein (LtrA)
HBOPLIAO_00681 2.3e-44 ltrA S Bacterial low temperature requirement A protein (LtrA)
HBOPLIAO_00682 1.6e-79 uspA T universal stress protein
HBOPLIAO_00683 1.5e-80 K AsnC family
HBOPLIAO_00684 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HBOPLIAO_00685 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
HBOPLIAO_00686 2e-180 galR K Transcriptional regulator
HBOPLIAO_00687 7.6e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HBOPLIAO_00688 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HBOPLIAO_00689 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HBOPLIAO_00690 4.4e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
HBOPLIAO_00691 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
HBOPLIAO_00692 9.1e-36
HBOPLIAO_00693 5.9e-52
HBOPLIAO_00694 2.3e-204
HBOPLIAO_00695 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HBOPLIAO_00696 8.9e-136 pnuC H nicotinamide mononucleotide transporter
HBOPLIAO_00697 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
HBOPLIAO_00698 3.2e-124 K response regulator
HBOPLIAO_00699 1.3e-179 T PhoQ Sensor
HBOPLIAO_00700 1.3e-134 macB2 V ABC transporter, ATP-binding protein
HBOPLIAO_00701 0.0 ysaB V FtsX-like permease family
HBOPLIAO_00702 8.9e-173 L PFAM Integrase catalytic region
HBOPLIAO_00703 1.5e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HBOPLIAO_00704 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HBOPLIAO_00705 1.6e-21 K helix_turn_helix, mercury resistance
HBOPLIAO_00706 9.2e-39 S Cytochrome B5
HBOPLIAO_00707 2.2e-156 yitU 3.1.3.104 S hydrolase
HBOPLIAO_00708 1.7e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HBOPLIAO_00709 2e-147 f42a O Band 7 protein
HBOPLIAO_00710 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HBOPLIAO_00711 2.4e-130 lytT K response regulator receiver
HBOPLIAO_00712 1.9e-66 lrgA S LrgA family
HBOPLIAO_00713 2.6e-124 lrgB M LrgB-like family
HBOPLIAO_00714 1.2e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HBOPLIAO_00715 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HBOPLIAO_00716 4.2e-189 galR K Periplasmic binding protein-like domain
HBOPLIAO_00717 0.0 rafA 3.2.1.22 G alpha-galactosidase
HBOPLIAO_00718 3.8e-87 S Protein of unknown function (DUF1440)
HBOPLIAO_00719 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HBOPLIAO_00720 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HBOPLIAO_00721 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HBOPLIAO_00722 5.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HBOPLIAO_00723 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HBOPLIAO_00724 2.9e-85 ypmB S Protein conserved in bacteria
HBOPLIAO_00725 3e-125 dnaD L DnaD domain protein
HBOPLIAO_00726 2e-161 EG EamA-like transporter family
HBOPLIAO_00727 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HBOPLIAO_00728 4e-56 K transcriptional regulator PadR family
HBOPLIAO_00729 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
HBOPLIAO_00730 6.4e-126 S Putative adhesin
HBOPLIAO_00731 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HBOPLIAO_00732 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBOPLIAO_00733 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBOPLIAO_00734 3.4e-35 nrdH O Glutaredoxin
HBOPLIAO_00735 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HBOPLIAO_00736 3.8e-297 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBOPLIAO_00737 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HBOPLIAO_00738 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HBOPLIAO_00739 9.7e-39 S Protein of unknown function (DUF2508)
HBOPLIAO_00740 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HBOPLIAO_00741 7.6e-52 yaaQ S Cyclic-di-AMP receptor
HBOPLIAO_00742 8.2e-185 holB 2.7.7.7 L DNA polymerase III
HBOPLIAO_00743 5.9e-58 yabA L Involved in initiation control of chromosome replication
HBOPLIAO_00744 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HBOPLIAO_00745 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
HBOPLIAO_00746 3.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HBOPLIAO_00747 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HBOPLIAO_00748 5.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HBOPLIAO_00749 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HBOPLIAO_00750 8.2e-48
HBOPLIAO_00751 7.8e-272 S ABC transporter, ATP-binding protein
HBOPLIAO_00752 2.3e-142 S Putative ABC-transporter type IV
HBOPLIAO_00753 3.4e-106 NU mannosyl-glycoprotein
HBOPLIAO_00754 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
HBOPLIAO_00755 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
HBOPLIAO_00756 4.9e-204 nrnB S DHHA1 domain
HBOPLIAO_00757 6.9e-49
HBOPLIAO_00758 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HBOPLIAO_00759 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HBOPLIAO_00760 2e-15 S Domain of unknown function (DUF4767)
HBOPLIAO_00761 9.5e-55
HBOPLIAO_00762 5.4e-116 yrkL S Flavodoxin-like fold
HBOPLIAO_00764 1.6e-64 yeaO S Protein of unknown function, DUF488
HBOPLIAO_00765 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HBOPLIAO_00766 3e-204 3.1.3.1 S associated with various cellular activities
HBOPLIAO_00767 4.2e-242 S Putative metallopeptidase domain
HBOPLIAO_00768 5.1e-47
HBOPLIAO_00769 0.0 pepO 3.4.24.71 O Peptidase family M13
HBOPLIAO_00770 8.4e-111 K Helix-turn-helix domain
HBOPLIAO_00771 2.1e-88 ymdB S Macro domain protein
HBOPLIAO_00772 1.6e-197 EGP Major facilitator Superfamily
HBOPLIAO_00773 7.8e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBOPLIAO_00774 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HBOPLIAO_00775 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HBOPLIAO_00776 1.6e-105 ypsA S Belongs to the UPF0398 family
HBOPLIAO_00777 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HBOPLIAO_00778 1.1e-83 F Belongs to the NrdI family
HBOPLIAO_00779 5.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HBOPLIAO_00780 3.4e-70 rnhA 3.1.26.4 L Ribonuclease HI
HBOPLIAO_00781 1.5e-65 esbA S Family of unknown function (DUF5322)
HBOPLIAO_00782 1.3e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HBOPLIAO_00783 2.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HBOPLIAO_00784 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
HBOPLIAO_00785 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HBOPLIAO_00786 0.0 FbpA K Fibronectin-binding protein
HBOPLIAO_00787 1.9e-161 degV S EDD domain protein, DegV family
HBOPLIAO_00788 3.8e-93
HBOPLIAO_00789 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HBOPLIAO_00790 1.1e-158 gspA M family 8
HBOPLIAO_00791 1.2e-160 S Alpha beta hydrolase
HBOPLIAO_00792 1.5e-94 K Acetyltransferase (GNAT) domain
HBOPLIAO_00793 1.5e-239 XK27_08635 S UPF0210 protein
HBOPLIAO_00794 2.1e-39 gcvR T Belongs to the UPF0237 family
HBOPLIAO_00795 1.7e-170 1.1.1.346 C Aldo keto reductase
HBOPLIAO_00796 1.3e-123 K LysR substrate binding domain protein
HBOPLIAO_00797 3.2e-83 C Flavodoxin
HBOPLIAO_00798 5.6e-79 yphH S Cupin domain
HBOPLIAO_00799 1e-73 yeaL S UPF0756 membrane protein
HBOPLIAO_00800 1.3e-244 EGP Major facilitator Superfamily
HBOPLIAO_00801 5e-75 copY K Copper transport repressor CopY TcrY
HBOPLIAO_00802 2.5e-245 yhdP S Transporter associated domain
HBOPLIAO_00803 0.0 ubiB S ABC1 family
HBOPLIAO_00804 9.6e-144 S DUF218 domain
HBOPLIAO_00805 3.2e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HBOPLIAO_00806 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBOPLIAO_00807 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HBOPLIAO_00808 0.0 uvrA3 L excinuclease ABC, A subunit
HBOPLIAO_00809 4.6e-123 S SNARE associated Golgi protein
HBOPLIAO_00810 1.9e-228 N Uncharacterized conserved protein (DUF2075)
HBOPLIAO_00811 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HBOPLIAO_00813 1e-254 yifK E Amino acid permease
HBOPLIAO_00814 5.5e-158 endA V DNA/RNA non-specific endonuclease
HBOPLIAO_00815 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBOPLIAO_00816 6.2e-76 K Transcriptional regulator, TetR family
HBOPLIAO_00817 4.3e-13 K Transcriptional regulator, TetR family
HBOPLIAO_00819 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HBOPLIAO_00820 3e-86
HBOPLIAO_00821 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HBOPLIAO_00822 9.6e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HBOPLIAO_00823 4.2e-261 nox C NADH oxidase
HBOPLIAO_00824 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
HBOPLIAO_00825 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HBOPLIAO_00826 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
HBOPLIAO_00827 3.8e-167 yvgN C Aldo keto reductase
HBOPLIAO_00828 6.6e-136 puuD S peptidase C26
HBOPLIAO_00829 8.1e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HBOPLIAO_00830 2.5e-209 yfeO P Voltage gated chloride channel
HBOPLIAO_00831 5.3e-226 sptS 2.7.13.3 T Histidine kinase
HBOPLIAO_00832 3.3e-118 K response regulator
HBOPLIAO_00833 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
HBOPLIAO_00834 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HBOPLIAO_00835 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HBOPLIAO_00836 1.1e-256 malT G Major Facilitator
HBOPLIAO_00838 2.8e-24
HBOPLIAO_00839 3.3e-158 spoU 2.1.1.185 J Methyltransferase
HBOPLIAO_00840 4.9e-224 oxlT P Major Facilitator Superfamily
HBOPLIAO_00841 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HBOPLIAO_00843 5.6e-225 S cog cog1373
HBOPLIAO_00844 3.1e-175 coaA 2.7.1.33 F Pantothenic acid kinase
HBOPLIAO_00845 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HBOPLIAO_00846 4.7e-157 EG EamA-like transporter family
HBOPLIAO_00847 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
HBOPLIAO_00848 0.0 helD 3.6.4.12 L DNA helicase
HBOPLIAO_00849 3.4e-115 dedA S SNARE associated Golgi protein
HBOPLIAO_00850 4.2e-126 3.1.3.73 G phosphoglycerate mutase
HBOPLIAO_00851 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBOPLIAO_00852 6.6e-35 S Transglycosylase associated protein
HBOPLIAO_00854 7.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBOPLIAO_00855 5.3e-221 V domain protein
HBOPLIAO_00856 1.6e-94 K Transcriptional regulator (TetR family)
HBOPLIAO_00857 5.8e-39 pspC KT PspC domain protein
HBOPLIAO_00858 8.3e-151
HBOPLIAO_00859 4e-17 3.2.1.14 GH18
HBOPLIAO_00860 1.5e-82 zur P Belongs to the Fur family
HBOPLIAO_00861 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
HBOPLIAO_00862 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HBOPLIAO_00863 6e-255 yfnA E Amino Acid
HBOPLIAO_00864 7.2e-234 EGP Sugar (and other) transporter
HBOPLIAO_00865 8.1e-230
HBOPLIAO_00866 4.3e-208 potD P ABC transporter
HBOPLIAO_00867 1.9e-139 potC P ABC transporter permease
HBOPLIAO_00868 4.5e-146 potB P ABC transporter permease
HBOPLIAO_00869 1.7e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HBOPLIAO_00870 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HBOPLIAO_00871 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HBOPLIAO_00872 0.0 pacL 3.6.3.8 P P-type ATPase
HBOPLIAO_00873 3.4e-85 dps P Belongs to the Dps family
HBOPLIAO_00874 2.8e-255 yagE E amino acid
HBOPLIAO_00875 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HBOPLIAO_00876 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HBOPLIAO_00877 1.7e-128 L Helix-turn-helix domain
HBOPLIAO_00878 5.8e-157 L hmm pf00665
HBOPLIAO_00884 1.3e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HBOPLIAO_00885 1.5e-275 lysP E amino acid
HBOPLIAO_00886 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
HBOPLIAO_00887 2.7e-120 lssY 3.6.1.27 I phosphatase
HBOPLIAO_00888 6.7e-81 S Threonine/Serine exporter, ThrE
HBOPLIAO_00889 3.6e-129 thrE S Putative threonine/serine exporter
HBOPLIAO_00890 3.5e-31 cspC K Cold shock protein
HBOPLIAO_00891 1.1e-124 sirR K iron dependent repressor
HBOPLIAO_00892 2.6e-166 czcD P cation diffusion facilitator family transporter
HBOPLIAO_00893 5e-117 S membrane
HBOPLIAO_00894 7.6e-110 S VIT family
HBOPLIAO_00895 5.5e-83 usp1 T Belongs to the universal stress protein A family
HBOPLIAO_00896 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HBOPLIAO_00897 7.5e-152 glnH ET ABC transporter
HBOPLIAO_00898 4.2e-110 gluC P ABC transporter permease
HBOPLIAO_00899 1.4e-108 glnP P ABC transporter permease
HBOPLIAO_00900 2.1e-216 S CAAX protease self-immunity
HBOPLIAO_00901 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HBOPLIAO_00902 2.5e-53
HBOPLIAO_00903 4.9e-73 merR K MerR HTH family regulatory protein
HBOPLIAO_00904 2.7e-269 lmrB EGP Major facilitator Superfamily
HBOPLIAO_00905 9.5e-119 S Domain of unknown function (DUF4811)
HBOPLIAO_00906 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HBOPLIAO_00908 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HBOPLIAO_00909 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HBOPLIAO_00910 3.4e-188 I Alpha beta
HBOPLIAO_00911 2e-283 emrY EGP Major facilitator Superfamily
HBOPLIAO_00912 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
HBOPLIAO_00913 2e-250 yjjP S Putative threonine/serine exporter
HBOPLIAO_00914 1e-159 mleR K LysR family
HBOPLIAO_00915 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
HBOPLIAO_00916 1.8e-267 frdC 1.3.5.4 C FAD binding domain
HBOPLIAO_00917 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HBOPLIAO_00918 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HBOPLIAO_00919 1.9e-161 mleR K LysR family
HBOPLIAO_00920 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBOPLIAO_00921 3.3e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HBOPLIAO_00922 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
HBOPLIAO_00923 3.6e-168 L transposase, IS605 OrfB family
HBOPLIAO_00924 2.7e-263 S Uncharacterized protein conserved in bacteria (DUF2252)
HBOPLIAO_00925 1.5e-25
HBOPLIAO_00926 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HBOPLIAO_00927 3e-75
HBOPLIAO_00928 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HBOPLIAO_00929 3.6e-83 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HBOPLIAO_00930 8.5e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HBOPLIAO_00931 1.5e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HBOPLIAO_00932 4.7e-102 T Ion transport 2 domain protein
HBOPLIAO_00933 0.0 S Bacterial membrane protein YfhO
HBOPLIAO_00934 5e-202 G Transporter, major facilitator family protein
HBOPLIAO_00935 1.3e-107 yvrI K sigma factor activity
HBOPLIAO_00936 3.5e-64 ydiI Q Thioesterase superfamily
HBOPLIAO_00937 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HBOPLIAO_00938 4.4e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HBOPLIAO_00939 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HBOPLIAO_00940 4.2e-32 feoA P FeoA domain
HBOPLIAO_00941 6.5e-145 sufC O FeS assembly ATPase SufC
HBOPLIAO_00942 7.3e-239 sufD O FeS assembly protein SufD
HBOPLIAO_00943 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBOPLIAO_00944 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
HBOPLIAO_00945 1.6e-271 sufB O assembly protein SufB
HBOPLIAO_00946 3.6e-57 yitW S Iron-sulfur cluster assembly protein
HBOPLIAO_00947 3.2e-161 hipB K Helix-turn-helix
HBOPLIAO_00948 7.8e-112 nreC K PFAM regulatory protein LuxR
HBOPLIAO_00949 5.3e-165 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBOPLIAO_00950 6.1e-216 patA 2.6.1.1 E Aminotransferase
HBOPLIAO_00951 7.8e-32
HBOPLIAO_00952 0.0 clpL O associated with various cellular activities
HBOPLIAO_00954 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
HBOPLIAO_00955 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBOPLIAO_00956 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HBOPLIAO_00957 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HBOPLIAO_00958 1.6e-171 malR K Transcriptional regulator, LacI family
HBOPLIAO_00959 1.4e-212 phbA 2.3.1.9 I Belongs to the thiolase family
HBOPLIAO_00960 7.7e-130 ponA V Beta-lactamase enzyme family
HBOPLIAO_00961 4.9e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HBOPLIAO_00962 6.3e-216 uhpT EGP Major facilitator Superfamily
HBOPLIAO_00963 1.6e-257 ytjP 3.5.1.18 E Dipeptidase
HBOPLIAO_00964 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
HBOPLIAO_00965 4.8e-179 yfeX P Peroxidase
HBOPLIAO_00966 1.4e-169 lsa S ABC transporter
HBOPLIAO_00967 4.6e-134 I alpha/beta hydrolase fold
HBOPLIAO_00968 8e-180 MA20_14895 S Conserved hypothetical protein 698
HBOPLIAO_00969 3.5e-67 S NADPH-dependent FMN reductase
HBOPLIAO_00970 8.7e-09 S NADPH-dependent FMN reductase
HBOPLIAO_00971 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HBOPLIAO_00972 6.2e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HBOPLIAO_00973 1e-232 mntH P H( )-stimulated, divalent metal cation uptake system
HBOPLIAO_00974 3.2e-79 Q Methyltransferase
HBOPLIAO_00975 5.3e-116 ktrA P domain protein
HBOPLIAO_00976 6.5e-238 ktrB P Potassium uptake protein
HBOPLIAO_00977 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HBOPLIAO_00978 7.7e-175 fecB P Periplasmic binding protein
HBOPLIAO_00979 1.4e-139 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HBOPLIAO_00980 1.8e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBOPLIAO_00981 3.3e-77 S Flavodoxin
HBOPLIAO_00982 3.7e-64 moaE 2.8.1.12 H MoaE protein
HBOPLIAO_00983 4.9e-35 moaD 2.8.1.12 H ThiS family
HBOPLIAO_00984 3.9e-218 narK P Transporter, major facilitator family protein
HBOPLIAO_00985 2.9e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HBOPLIAO_00986 3.6e-182
HBOPLIAO_00987 4.6e-18
HBOPLIAO_00988 2.3e-116 nreC K PFAM regulatory protein LuxR
HBOPLIAO_00989 1.8e-190 comP 2.7.13.3 F Sensor histidine kinase
HBOPLIAO_00990 3e-44
HBOPLIAO_00991 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HBOPLIAO_00992 5.1e-84 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HBOPLIAO_00993 8.5e-229 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HBOPLIAO_00994 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HBOPLIAO_00995 3.3e-186 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HBOPLIAO_00996 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HBOPLIAO_00997 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HBOPLIAO_00998 6.9e-96 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HBOPLIAO_00999 7.6e-126 narI 1.7.5.1 C Nitrate reductase
HBOPLIAO_01000 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
HBOPLIAO_01001 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HBOPLIAO_01002 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HBOPLIAO_01003 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HBOPLIAO_01004 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HBOPLIAO_01005 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HBOPLIAO_01006 2.8e-31 yajC U Preprotein translocase
HBOPLIAO_01007 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HBOPLIAO_01008 3.2e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HBOPLIAO_01009 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HBOPLIAO_01010 4.1e-43 yrzL S Belongs to the UPF0297 family
HBOPLIAO_01011 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HBOPLIAO_01012 6.1e-48 yrzB S Belongs to the UPF0473 family
HBOPLIAO_01013 1.7e-85 cvpA S Colicin V production protein
HBOPLIAO_01014 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HBOPLIAO_01015 6.1e-54 trxA O Belongs to the thioredoxin family
HBOPLIAO_01016 1.7e-202 2.7.7.65 T GGDEF domain
HBOPLIAO_01017 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HBOPLIAO_01018 3.9e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HBOPLIAO_01019 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
HBOPLIAO_01020 2e-92 folT S ECF transporter, substrate-specific component
HBOPLIAO_01021 0.0 pepN 3.4.11.2 E aminopeptidase
HBOPLIAO_01022 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
HBOPLIAO_01023 9.8e-255 pepC 3.4.22.40 E aminopeptidase
HBOPLIAO_01024 6.5e-210 EGP Major facilitator Superfamily
HBOPLIAO_01025 1.8e-229
HBOPLIAO_01026 5.5e-26 K Transcriptional regulator, HxlR family
HBOPLIAO_01027 1.6e-43 K Transcriptional regulator, HxlR family
HBOPLIAO_01028 3.7e-108 XK27_02070 S Nitroreductase family
HBOPLIAO_01029 2.5e-52 hxlR K Transcriptional regulator, HxlR family
HBOPLIAO_01030 3e-119 GM NmrA-like family
HBOPLIAO_01031 1.7e-70 elaA S Gnat family
HBOPLIAO_01032 1.7e-33 S Cytochrome B5
HBOPLIAO_01033 5.4e-09 S Cytochrome B5
HBOPLIAO_01034 7.8e-41 S Cytochrome B5
HBOPLIAO_01035 1.5e-211 yxjG_1 E methionine synthase, vitamin-B12 independent
HBOPLIAO_01037 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBOPLIAO_01038 1.6e-131 S Hydrolases of the alpha beta superfamily
HBOPLIAO_01039 1.3e-16 S Hydrolases of the alpha beta superfamily
HBOPLIAO_01040 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HBOPLIAO_01041 3.4e-77 ctsR K Belongs to the CtsR family
HBOPLIAO_01042 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HBOPLIAO_01043 1e-110 K Bacterial regulatory proteins, tetR family
HBOPLIAO_01044 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBOPLIAO_01045 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBOPLIAO_01046 2.2e-202 ykiI
HBOPLIAO_01047 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HBOPLIAO_01048 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HBOPLIAO_01049 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HBOPLIAO_01050 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HBOPLIAO_01051 7.3e-90 L Transposase
HBOPLIAO_01052 2.4e-235 pbuG S permease
HBOPLIAO_01053 1.1e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HBOPLIAO_01054 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HBOPLIAO_01055 2.5e-135 S Belongs to the UPF0246 family
HBOPLIAO_01056 2.5e-138 S Membrane
HBOPLIAO_01057 8.1e-75 4.4.1.5 E Glyoxalase
HBOPLIAO_01058 1.5e-21
HBOPLIAO_01059 7.1e-86 yueI S Protein of unknown function (DUF1694)
HBOPLIAO_01060 1.7e-235 rarA L recombination factor protein RarA
HBOPLIAO_01061 4.4e-46
HBOPLIAO_01062 4.3e-83 usp6 T universal stress protein
HBOPLIAO_01063 2.8e-207 araR K Transcriptional regulator
HBOPLIAO_01064 7.1e-158 ytbE 1.1.1.346 S Aldo keto reductase
HBOPLIAO_01065 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
HBOPLIAO_01066 1.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HBOPLIAO_01067 7e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HBOPLIAO_01068 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
HBOPLIAO_01069 9.8e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HBOPLIAO_01070 2e-138 IQ reductase
HBOPLIAO_01071 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
HBOPLIAO_01072 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HBOPLIAO_01073 4.3e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HBOPLIAO_01074 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HBOPLIAO_01075 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HBOPLIAO_01076 2.1e-202 camS S sex pheromone
HBOPLIAO_01077 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBOPLIAO_01078 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HBOPLIAO_01079 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBOPLIAO_01080 5.1e-187 yegS 2.7.1.107 G Lipid kinase
HBOPLIAO_01081 2.1e-260 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBOPLIAO_01082 9.5e-47 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HBOPLIAO_01083 0.0 L Helicase C-terminal domain protein
HBOPLIAO_01084 1.4e-20
HBOPLIAO_01085 7.4e-68 rmaI K Transcriptional regulator
HBOPLIAO_01086 5.4e-235 EGP Major facilitator Superfamily
HBOPLIAO_01087 2.9e-111 yvyE 3.4.13.9 S YigZ family
HBOPLIAO_01088 1.4e-256 comFA L Helicase C-terminal domain protein
HBOPLIAO_01089 1.3e-114 comFC S Competence protein
HBOPLIAO_01090 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HBOPLIAO_01091 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HBOPLIAO_01092 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HBOPLIAO_01093 3.1e-32 KT PspC domain protein
HBOPLIAO_01094 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HBOPLIAO_01095 7.8e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HBOPLIAO_01096 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HBOPLIAO_01097 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HBOPLIAO_01098 7.4e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HBOPLIAO_01099 3.9e-136 yrjD S LUD domain
HBOPLIAO_01100 7.5e-288 lutB C 4Fe-4S dicluster domain
HBOPLIAO_01101 3.5e-163 lutA C Cysteine-rich domain
HBOPLIAO_01102 1.5e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HBOPLIAO_01103 1.8e-147 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HBOPLIAO_01104 3.3e-83
HBOPLIAO_01105 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HBOPLIAO_01106 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
HBOPLIAO_01107 2.9e-34
HBOPLIAO_01108 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HBOPLIAO_01109 9.9e-261 yfnA E amino acid
HBOPLIAO_01110 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HBOPLIAO_01111 9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HBOPLIAO_01112 1e-38 ylqC S Belongs to the UPF0109 family
HBOPLIAO_01113 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HBOPLIAO_01114 2.3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBOPLIAO_01115 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HBOPLIAO_01116 2.7e-179 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HBOPLIAO_01117 0.0 smc D Required for chromosome condensation and partitioning
HBOPLIAO_01118 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HBOPLIAO_01119 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBOPLIAO_01120 6.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HBOPLIAO_01121 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBOPLIAO_01122 7.1e-311 yloV S DAK2 domain fusion protein YloV
HBOPLIAO_01123 4.7e-58 asp S Asp23 family, cell envelope-related function
HBOPLIAO_01124 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HBOPLIAO_01125 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HBOPLIAO_01126 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HBOPLIAO_01127 3.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HBOPLIAO_01128 0.0 KLT serine threonine protein kinase
HBOPLIAO_01129 2.9e-131 stp 3.1.3.16 T phosphatase
HBOPLIAO_01130 9.6e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HBOPLIAO_01131 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HBOPLIAO_01132 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBOPLIAO_01133 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBOPLIAO_01134 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HBOPLIAO_01135 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HBOPLIAO_01136 1.7e-54
HBOPLIAO_01137 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
HBOPLIAO_01138 3.3e-77 argR K Regulates arginine biosynthesis genes
HBOPLIAO_01139 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HBOPLIAO_01140 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HBOPLIAO_01141 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HBOPLIAO_01142 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HBOPLIAO_01143 2.1e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HBOPLIAO_01144 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HBOPLIAO_01145 2.2e-70 yqhY S Asp23 family, cell envelope-related function
HBOPLIAO_01146 1.7e-114 J 2'-5' RNA ligase superfamily
HBOPLIAO_01147 1.1e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HBOPLIAO_01148 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HBOPLIAO_01149 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HBOPLIAO_01150 1.6e-54 ysxB J Cysteine protease Prp
HBOPLIAO_01151 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HBOPLIAO_01152 8.3e-111 K Transcriptional regulator
HBOPLIAO_01156 2.5e-89 dut S Protein conserved in bacteria
HBOPLIAO_01157 6.6e-174
HBOPLIAO_01158 1e-151
HBOPLIAO_01159 3.7e-51 S Iron-sulfur cluster assembly protein
HBOPLIAO_01160 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HBOPLIAO_01161 2.2e-154 P Belongs to the nlpA lipoprotein family
HBOPLIAO_01162 3.9e-12
HBOPLIAO_01163 1.9e-178 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HBOPLIAO_01164 3.8e-19 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HBOPLIAO_01165 3.8e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBOPLIAO_01166 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
HBOPLIAO_01167 4.4e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HBOPLIAO_01168 1.3e-21 S Protein of unknown function (DUF3042)
HBOPLIAO_01169 3.4e-67 yqhL P Rhodanese-like protein
HBOPLIAO_01170 5.6e-183 glk 2.7.1.2 G Glucokinase
HBOPLIAO_01171 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HBOPLIAO_01172 1.4e-26 gluP 3.4.21.105 S Peptidase, S54 family
HBOPLIAO_01173 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
HBOPLIAO_01174 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBOPLIAO_01175 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HBOPLIAO_01176 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HBOPLIAO_01177 0.0 S membrane
HBOPLIAO_01178 8.8e-71 yneR S Belongs to the HesB IscA family
HBOPLIAO_01179 1.2e-23 M LPXTG-motif cell wall anchor domain protein
HBOPLIAO_01180 0.0 M LPXTG-motif cell wall anchor domain protein
HBOPLIAO_01181 4.4e-181 M LPXTG-motif cell wall anchor domain protein
HBOPLIAO_01182 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HBOPLIAO_01183 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
HBOPLIAO_01184 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HBOPLIAO_01185 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HBOPLIAO_01188 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HBOPLIAO_01189 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
HBOPLIAO_01190 2.4e-223 mdtG EGP Major facilitator Superfamily
HBOPLIAO_01191 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HBOPLIAO_01192 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HBOPLIAO_01193 1.5e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HBOPLIAO_01194 5.4e-220 norA EGP Major facilitator Superfamily
HBOPLIAO_01195 5e-44 1.3.5.4 S FMN binding
HBOPLIAO_01196 5.4e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBOPLIAO_01197 4.3e-267 yfnA E amino acid
HBOPLIAO_01198 4.8e-257 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBOPLIAO_01200 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HBOPLIAO_01201 0.0 helD 3.6.4.12 L DNA helicase
HBOPLIAO_01202 8.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
HBOPLIAO_01203 2.2e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HBOPLIAO_01204 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HBOPLIAO_01205 8.7e-182 L COG2826 Transposase and inactivated derivatives, IS30 family
HBOPLIAO_01206 4.3e-64 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HBOPLIAO_01207 5.9e-32 aatB ET PFAM extracellular solute-binding protein, family 3
HBOPLIAO_01208 3.5e-103 aatB ET PFAM extracellular solute-binding protein, family 3
HBOPLIAO_01209 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
HBOPLIAO_01210 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HBOPLIAO_01211 2.3e-116 yfbR S HD containing hydrolase-like enzyme
HBOPLIAO_01212 1.5e-13
HBOPLIAO_01213 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HBOPLIAO_01214 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HBOPLIAO_01215 5.4e-245 steT E amino acid
HBOPLIAO_01216 1.1e-161 rapZ S Displays ATPase and GTPase activities
HBOPLIAO_01217 4.2e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HBOPLIAO_01218 4e-170 whiA K May be required for sporulation
HBOPLIAO_01220 8.8e-15
HBOPLIAO_01221 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HBOPLIAO_01223 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HBOPLIAO_01224 3.2e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HBOPLIAO_01225 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HBOPLIAO_01226 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HBOPLIAO_01227 7.1e-248 yifK E Amino acid permease
HBOPLIAO_01228 2.7e-26 K TRANSCRIPTIONal
HBOPLIAO_01230 1.8e-132 L PFAM Integrase catalytic region
HBOPLIAO_01231 1.1e-130 arsB 1.20.4.1 P Sodium Bile acid symporter family
HBOPLIAO_01232 9.4e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBOPLIAO_01233 3e-18
HBOPLIAO_01234 8.2e-52 L Resolvase, N terminal domain
HBOPLIAO_01235 2.9e-50
HBOPLIAO_01237 0.0 copB 3.6.3.4 P P-type ATPase
HBOPLIAO_01238 9.4e-74 K Copper transport repressor CopY TcrY
HBOPLIAO_01239 2e-39 ycfA K Bacterial regulatory proteins, tetR family
HBOPLIAO_01240 2.1e-80 arbZ I Phosphate acyltransferases
HBOPLIAO_01241 9.8e-79 arbY M family 8
HBOPLIAO_01242 2.1e-77 arbx M Glycosyl transferase family 8
HBOPLIAO_01243 1.2e-55 arbV 2.3.1.51 I Phosphate acyltransferases
HBOPLIAO_01244 6.3e-168 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HBOPLIAO_01245 1.9e-56 cadX K Bacterial regulatory protein, arsR family
HBOPLIAO_01246 2.8e-95 cadD P Cadmium resistance transporter
HBOPLIAO_01247 3.5e-174 S Protein of unknown function DUF262
HBOPLIAO_01248 3.5e-95 L Integrase
HBOPLIAO_01249 4.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HBOPLIAO_01250 5e-229 ndh 1.6.99.3 C NADH dehydrogenase
HBOPLIAO_01251 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HBOPLIAO_01252 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HBOPLIAO_01253 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HBOPLIAO_01254 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
HBOPLIAO_01255 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HBOPLIAO_01256 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HBOPLIAO_01257 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HBOPLIAO_01258 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HBOPLIAO_01259 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HBOPLIAO_01260 3.3e-78 K Transcriptional regulator
HBOPLIAO_01261 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HBOPLIAO_01262 2.3e-155 ypuA S Protein of unknown function (DUF1002)
HBOPLIAO_01263 3.6e-66 GM NAD(P)H-binding
HBOPLIAO_01264 3.3e-92 padR K Virulence activator alpha C-term
HBOPLIAO_01265 3.3e-92 padC Q Phenolic acid decarboxylase
HBOPLIAO_01266 2e-152 S Alpha beta hydrolase
HBOPLIAO_01267 9.4e-32 S thiolester hydrolase activity
HBOPLIAO_01268 6.3e-88 lacA S transferase hexapeptide repeat
HBOPLIAO_01269 5.6e-158 K Transcriptional regulator
HBOPLIAO_01270 2.7e-85 C Flavodoxin
HBOPLIAO_01271 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
HBOPLIAO_01272 4e-165 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HBOPLIAO_01273 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HBOPLIAO_01274 5.3e-83 K Bacterial regulatory proteins, tetR family
HBOPLIAO_01275 4.3e-55 yphJ 4.1.1.44 S decarboxylase
HBOPLIAO_01276 6e-10 P FAD-binding domain
HBOPLIAO_01277 6.4e-21 P nitric oxide dioxygenase activity
HBOPLIAO_01278 4.7e-109 S Peptidase propeptide and YPEB domain
HBOPLIAO_01279 9.9e-239 T GHKL domain
HBOPLIAO_01280 3.6e-120 T Transcriptional regulatory protein, C terminal
HBOPLIAO_01281 3.9e-27 mleP3 S Membrane transport protein
HBOPLIAO_01282 4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HBOPLIAO_01283 1.3e-20
HBOPLIAO_01284 8.1e-90 ntd 2.4.2.6 F Nucleoside
HBOPLIAO_01285 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
HBOPLIAO_01286 1.6e-45 yrvD S Pfam:DUF1049
HBOPLIAO_01288 1.1e-35 S Phage derived protein Gp49-like (DUF891)
HBOPLIAO_01289 8.5e-20 K Helix-turn-helix XRE-family like proteins
HBOPLIAO_01290 1.7e-78 I alpha/beta hydrolase fold
HBOPLIAO_01291 1.1e-113 frnE Q DSBA-like thioredoxin domain
HBOPLIAO_01292 4.6e-49
HBOPLIAO_01293 7.8e-263 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HBOPLIAO_01294 7.2e-43 G Major Facilitator
HBOPLIAO_01295 8.8e-209 G Major Facilitator
HBOPLIAO_01296 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HBOPLIAO_01297 9.6e-263 M domain protein
HBOPLIAO_01298 2.3e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HBOPLIAO_01299 1.7e-266 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HBOPLIAO_01300 2.2e-72
HBOPLIAO_01302 2.6e-191 nss M transferase activity, transferring glycosyl groups
HBOPLIAO_01303 3.1e-143 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HBOPLIAO_01304 2.6e-195 M transferase activity, transferring glycosyl groups
HBOPLIAO_01305 5.3e-217 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HBOPLIAO_01306 1.7e-154 asp3 S Accessory Sec secretory system ASP3
HBOPLIAO_01307 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HBOPLIAO_01308 1.9e-225 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HBOPLIAO_01309 7.9e-196 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HBOPLIAO_01313 7e-08 UW Hep Hag repeat protein
HBOPLIAO_01314 8.1e-35
HBOPLIAO_01315 1.3e-102 K DNA-templated transcription, initiation
HBOPLIAO_01316 9.5e-30
HBOPLIAO_01317 2.1e-60 L PFAM transposase IS200-family protein
HBOPLIAO_01318 2.5e-230 L transposase, IS605 OrfB family
HBOPLIAO_01319 1.9e-34 T Toxin-antitoxin system, toxin component, MazF family
HBOPLIAO_01320 8.9e-37
HBOPLIAO_01322 0.0 snf 2.7.11.1 KL domain protein
HBOPLIAO_01323 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
HBOPLIAO_01324 1.7e-176 M Glycosyl hydrolases family 25
HBOPLIAO_01325 7.6e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HBOPLIAO_01326 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HBOPLIAO_01327 1.2e-25 czrA K Transcriptional regulator, ArsR family
HBOPLIAO_01328 4.6e-38
HBOPLIAO_01329 0.0 yhcA V ABC transporter, ATP-binding protein
HBOPLIAO_01330 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HBOPLIAO_01331 1.7e-177 hrtB V ABC transporter permease
HBOPLIAO_01332 2.6e-86 ygfC K transcriptional regulator (TetR family)
HBOPLIAO_01333 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HBOPLIAO_01334 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
HBOPLIAO_01335 3e-34
HBOPLIAO_01336 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HBOPLIAO_01338 3.1e-226 yxiO S Vacuole effluxer Atg22 like
HBOPLIAO_01339 2.8e-215 npp S type I phosphodiesterase nucleotide pyrophosphatase
HBOPLIAO_01340 1.6e-52 azlD S branched-chain amino acid
HBOPLIAO_01341 3.7e-136 azlC E AzlC protein
HBOPLIAO_01342 6.5e-199 hpk31 2.7.13.3 T Histidine kinase
HBOPLIAO_01343 1.2e-123 K response regulator
HBOPLIAO_01344 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HBOPLIAO_01345 9.5e-172 deoR K sugar-binding domain protein
HBOPLIAO_01346 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HBOPLIAO_01347 7.9e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HBOPLIAO_01348 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HBOPLIAO_01349 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HBOPLIAO_01350 7.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
HBOPLIAO_01351 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HBOPLIAO_01352 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
HBOPLIAO_01353 1.7e-154 spo0J K Belongs to the ParB family
HBOPLIAO_01354 3.9e-139 soj D Sporulation initiation inhibitor
HBOPLIAO_01355 4.3e-151 noc K Belongs to the ParB family
HBOPLIAO_01356 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HBOPLIAO_01357 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HBOPLIAO_01358 5.6e-169 rihC 3.2.2.1 F Nucleoside
HBOPLIAO_01359 3.3e-217 nupG F Nucleoside transporter
HBOPLIAO_01360 7.2e-221 cycA E Amino acid permease
HBOPLIAO_01362 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HBOPLIAO_01363 1.2e-264 glnP P ABC transporter
HBOPLIAO_01364 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HBOPLIAO_01365 2.5e-158 L hmm pf00665
HBOPLIAO_01366 3.6e-74 L Helix-turn-helix domain
HBOPLIAO_01367 2.3e-08 L Helix-turn-helix domain
HBOPLIAO_01368 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBOPLIAO_01369 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HBOPLIAO_01370 9e-119 S Repeat protein
HBOPLIAO_01371 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HBOPLIAO_01372 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HBOPLIAO_01373 1.3e-57 XK27_04120 S Putative amino acid metabolism
HBOPLIAO_01374 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
HBOPLIAO_01375 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBOPLIAO_01377 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HBOPLIAO_01378 4.2e-32 cspA K Cold shock protein
HBOPLIAO_01379 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HBOPLIAO_01380 1.9e-42 divIVA D DivIVA domain protein
HBOPLIAO_01381 5.1e-142 ylmH S S4 domain protein
HBOPLIAO_01382 3.2e-40 yggT S YGGT family
HBOPLIAO_01383 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HBOPLIAO_01384 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBOPLIAO_01385 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HBOPLIAO_01386 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HBOPLIAO_01387 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HBOPLIAO_01388 2.9e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HBOPLIAO_01389 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBOPLIAO_01390 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HBOPLIAO_01391 2.6e-56 ftsL D Cell division protein FtsL
HBOPLIAO_01392 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HBOPLIAO_01393 3.1e-77 mraZ K Belongs to the MraZ family
HBOPLIAO_01394 7.3e-56
HBOPLIAO_01395 1.2e-10 S Protein of unknown function (DUF4044)
HBOPLIAO_01396 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HBOPLIAO_01397 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HBOPLIAO_01398 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
HBOPLIAO_01399 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HBOPLIAO_01401 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
HBOPLIAO_01402 7.8e-296 L Transposase IS66 family
HBOPLIAO_01403 0.0 cadA P P-type ATPase
HBOPLIAO_01404 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
HBOPLIAO_01406 2.4e-153 1.6.5.2 GM NAD(P)H-binding
HBOPLIAO_01407 1.3e-73 K Transcriptional regulator
HBOPLIAO_01408 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
HBOPLIAO_01409 8.2e-109 proWZ P ABC transporter permease
HBOPLIAO_01410 1e-139 proV E ABC transporter, ATP-binding protein
HBOPLIAO_01411 4.5e-104 proW P ABC transporter, permease protein
HBOPLIAO_01412 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HBOPLIAO_01413 7.8e-252 clcA P chloride
HBOPLIAO_01414 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HBOPLIAO_01415 3.1e-103 metI P ABC transporter permease
HBOPLIAO_01416 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBOPLIAO_01417 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
HBOPLIAO_01418 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HBOPLIAO_01419 3.3e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HBOPLIAO_01420 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HBOPLIAO_01421 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HBOPLIAO_01422 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HBOPLIAO_01423 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HBOPLIAO_01424 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HBOPLIAO_01425 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HBOPLIAO_01426 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HBOPLIAO_01427 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HBOPLIAO_01428 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HBOPLIAO_01429 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HBOPLIAO_01430 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HBOPLIAO_01431 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HBOPLIAO_01432 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HBOPLIAO_01433 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HBOPLIAO_01434 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HBOPLIAO_01435 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HBOPLIAO_01436 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HBOPLIAO_01437 2.9e-24 rpmD J Ribosomal protein L30
HBOPLIAO_01438 8.9e-64 rplO J Binds to the 23S rRNA
HBOPLIAO_01439 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HBOPLIAO_01440 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HBOPLIAO_01441 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HBOPLIAO_01442 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HBOPLIAO_01443 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HBOPLIAO_01444 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HBOPLIAO_01445 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HBOPLIAO_01446 1.1e-62 rplQ J Ribosomal protein L17
HBOPLIAO_01451 9e-41 L Psort location Cytoplasmic, score 8.96
HBOPLIAO_01452 1.1e-38 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HBOPLIAO_01453 3e-16 L transposase and inactivated derivatives, IS30 family
HBOPLIAO_01454 5e-128 yocS S Transporter
HBOPLIAO_01455 1e-27 XK27_02560 S Pfam:DUF59
HBOPLIAO_01456 7.6e-260 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HBOPLIAO_01457 2.1e-106 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HBOPLIAO_01458 0.0 ilvD 4.2.1.9 EG Belongs to the IlvD Edd family
HBOPLIAO_01459 1.2e-39 S Iron-sulfur cluster assembly protein
HBOPLIAO_01460 3e-155 yocS S SBF-like CPA transporter family (DUF4137)
HBOPLIAO_01461 2.8e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
HBOPLIAO_01462 1.8e-209 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HBOPLIAO_01463 4.7e-76 M transferase activity, transferring glycosyl groups
HBOPLIAO_01464 2.2e-88 cps3F
HBOPLIAO_01465 3e-28 M biosynthesis protein
HBOPLIAO_01466 2.4e-77 rgpB GT2 M Glycosyl transferase family 2
HBOPLIAO_01467 4.4e-66 S Glycosyltransferase like family
HBOPLIAO_01468 4.9e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HBOPLIAO_01469 3.1e-73 S Acyltransferase family
HBOPLIAO_01470 3.6e-35
HBOPLIAO_01471 1.6e-71 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HBOPLIAO_01472 6.9e-165 ykoT GT2 M Glycosyl transferase family 2
HBOPLIAO_01473 7.9e-31 S integral membrane protein
HBOPLIAO_01474 1.5e-08 S integral membrane protein
HBOPLIAO_01475 7.1e-240 E amino acid
HBOPLIAO_01476 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HBOPLIAO_01477 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HBOPLIAO_01478 8.1e-154 KT YcbB domain
HBOPLIAO_01479 1.9e-302 xylB 2.7.1.17 G Belongs to the FGGY kinase family
HBOPLIAO_01480 7.6e-271 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HBOPLIAO_01481 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
HBOPLIAO_01482 2.8e-45 pgdA 3.5.1.104 G polysaccharide deacetylase
HBOPLIAO_01483 0.0 3.2.1.55 GH51 G Right handed beta helix region
HBOPLIAO_01484 1.6e-290 xynT G MFS/sugar transport protein
HBOPLIAO_01486 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
HBOPLIAO_01487 1.3e-293 lmrA 3.6.3.44 V ABC transporter
HBOPLIAO_01489 6.8e-130 K response regulator
HBOPLIAO_01490 0.0 vicK 2.7.13.3 T Histidine kinase
HBOPLIAO_01491 2.1e-246 yycH S YycH protein
HBOPLIAO_01492 2.7e-149 yycI S YycH protein
HBOPLIAO_01493 3.8e-153 vicX 3.1.26.11 S domain protein
HBOPLIAO_01494 9.6e-215 htrA 3.4.21.107 O serine protease
HBOPLIAO_01495 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HBOPLIAO_01496 4.7e-177 ABC-SBP S ABC transporter
HBOPLIAO_01497 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HBOPLIAO_01499 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
HBOPLIAO_01500 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HBOPLIAO_01501 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
HBOPLIAO_01502 5.1e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HBOPLIAO_01503 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBOPLIAO_01504 2.7e-39 ptsH G phosphocarrier protein HPR
HBOPLIAO_01505 2.9e-27
HBOPLIAO_01506 0.0 clpE O Belongs to the ClpA ClpB family
HBOPLIAO_01507 2.4e-99 S Pfam:DUF3816
HBOPLIAO_01508 4e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HBOPLIAO_01509 6.7e-114
HBOPLIAO_01510 3.6e-157 V ABC transporter, ATP-binding protein
HBOPLIAO_01511 9.3e-65 gntR1 K Transcriptional regulator, GntR family
HBOPLIAO_01512 6.7e-99 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HBOPLIAO_01513 7.3e-115 K Transcriptional regulator
HBOPLIAO_01514 1e-293 M Exporter of polyketide antibiotics
HBOPLIAO_01515 2.6e-169 yjjC V ABC transporter
HBOPLIAO_01516 3.6e-45
HBOPLIAO_01517 3.2e-101 L Integrase
HBOPLIAO_01518 3.5e-61 S Phage derived protein Gp49-like (DUF891)
HBOPLIAO_01519 3.7e-39 K Helix-turn-helix domain
HBOPLIAO_01528 6.9e-09 S HTH domain
HBOPLIAO_01529 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBOPLIAO_01530 1.4e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HBOPLIAO_01531 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HBOPLIAO_01532 2e-194 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HBOPLIAO_01533 1.8e-184 M family 8
HBOPLIAO_01534 5.4e-181 GT2 M Glycosyltransferase like family 2
HBOPLIAO_01535 7.5e-183 M Glycosyl transferase, family 2
HBOPLIAO_01536 2e-233 S Psort location CytoplasmicMembrane, score 9.99
HBOPLIAO_01537 5.1e-238 S polysaccharide biosynthetic process
HBOPLIAO_01538 1.4e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
HBOPLIAO_01539 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HBOPLIAO_01540 2.4e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HBOPLIAO_01541 5.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HBOPLIAO_01542 3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HBOPLIAO_01543 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HBOPLIAO_01544 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HBOPLIAO_01545 2.6e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HBOPLIAO_01546 9.3e-130 IQ reductase
HBOPLIAO_01547 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HBOPLIAO_01548 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBOPLIAO_01549 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HBOPLIAO_01550 4.2e-77 marR K Transcriptional regulator, MarR family
HBOPLIAO_01551 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HBOPLIAO_01553 2.8e-199 xerS L Belongs to the 'phage' integrase family
HBOPLIAO_01554 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HBOPLIAO_01555 1.7e-84 F NUDIX domain
HBOPLIAO_01556 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HBOPLIAO_01557 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HBOPLIAO_01558 5.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HBOPLIAO_01559 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
HBOPLIAO_01560 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HBOPLIAO_01561 2.1e-160 dprA LU DNA protecting protein DprA
HBOPLIAO_01562 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBOPLIAO_01563 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HBOPLIAO_01564 4.4e-35 yozE S Belongs to the UPF0346 family
HBOPLIAO_01565 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HBOPLIAO_01566 9.5e-172 ypmR E lipolytic protein G-D-S-L family
HBOPLIAO_01567 1.7e-151 DegV S EDD domain protein, DegV family
HBOPLIAO_01568 5.3e-113 hlyIII S protein, hemolysin III
HBOPLIAO_01569 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBOPLIAO_01570 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HBOPLIAO_01571 0.0 yfmR S ABC transporter, ATP-binding protein
HBOPLIAO_01572 2.1e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HBOPLIAO_01573 1.5e-236 S Tetratricopeptide repeat protein
HBOPLIAO_01574 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HBOPLIAO_01575 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HBOPLIAO_01576 2.5e-204 rpsA 1.17.7.4 J Ribosomal protein S1
HBOPLIAO_01577 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HBOPLIAO_01578 8.8e-26 M Lysin motif
HBOPLIAO_01579 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HBOPLIAO_01580 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
HBOPLIAO_01581 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HBOPLIAO_01582 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HBOPLIAO_01583 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HBOPLIAO_01584 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HBOPLIAO_01585 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HBOPLIAO_01586 5.9e-163 xerD D recombinase XerD
HBOPLIAO_01587 2.3e-167 cvfB S S1 domain
HBOPLIAO_01588 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HBOPLIAO_01589 0.0 dnaE 2.7.7.7 L DNA polymerase
HBOPLIAO_01590 3e-30 S Protein of unknown function (DUF2929)
HBOPLIAO_01591 1.1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HBOPLIAO_01592 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBOPLIAO_01593 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
HBOPLIAO_01594 1.2e-219 patA 2.6.1.1 E Aminotransferase
HBOPLIAO_01595 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HBOPLIAO_01596 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HBOPLIAO_01597 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HBOPLIAO_01598 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HBOPLIAO_01599 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
HBOPLIAO_01600 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBOPLIAO_01601 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HBOPLIAO_01602 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HBOPLIAO_01603 2.9e-145 phoH T phosphate starvation-inducible protein PhoH
HBOPLIAO_01604 3.5e-21 phoH T phosphate starvation-inducible protein PhoH
HBOPLIAO_01605 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HBOPLIAO_01606 1.1e-90 bioY S BioY family
HBOPLIAO_01607 3.9e-262 argH 4.3.2.1 E argininosuccinate lyase
HBOPLIAO_01608 1.2e-134 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HBOPLIAO_01609 5.5e-40 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HBOPLIAO_01610 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HBOPLIAO_01611 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HBOPLIAO_01612 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HBOPLIAO_01613 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBOPLIAO_01614 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HBOPLIAO_01615 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HBOPLIAO_01616 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HBOPLIAO_01617 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HBOPLIAO_01618 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HBOPLIAO_01619 1.3e-226 aadAT EK Aminotransferase, class I
HBOPLIAO_01621 3.4e-244 M Glycosyl transferase family group 2
HBOPLIAO_01622 3.9e-60 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HBOPLIAO_01623 2.7e-126 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HBOPLIAO_01624 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HBOPLIAO_01625 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HBOPLIAO_01626 1.5e-48
HBOPLIAO_01628 8.2e-145 M domain, Protein
HBOPLIAO_01630 5.7e-11 K Cro/C1-type HTH DNA-binding domain
HBOPLIAO_01635 2.7e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HBOPLIAO_01636 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HBOPLIAO_01637 1.6e-177
HBOPLIAO_01638 1e-130 cobB K SIR2 family
HBOPLIAO_01640 3.6e-162 yunF F Protein of unknown function DUF72
HBOPLIAO_01641 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBOPLIAO_01642 1.9e-155 tatD L hydrolase, TatD family
HBOPLIAO_01643 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HBOPLIAO_01644 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HBOPLIAO_01645 6.8e-37 veg S Biofilm formation stimulator VEG
HBOPLIAO_01646 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HBOPLIAO_01647 4.1e-16 UW LPXTG-motif cell wall anchor domain protein
HBOPLIAO_01648 8.5e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HBOPLIAO_01649 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HBOPLIAO_01650 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HBOPLIAO_01651 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HBOPLIAO_01652 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HBOPLIAO_01653 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBOPLIAO_01654 5.8e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HBOPLIAO_01655 5.5e-217 patA 2.6.1.1 E Aminotransferase
HBOPLIAO_01656 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HBOPLIAO_01657 6.8e-121 radC L DNA repair protein
HBOPLIAO_01658 1.7e-179 mreB D cell shape determining protein MreB
HBOPLIAO_01659 2.2e-151 mreC M Involved in formation and maintenance of cell shape
HBOPLIAO_01660 1.2e-91 mreD M rod shape-determining protein MreD
HBOPLIAO_01661 3.2e-102 glnP P ABC transporter permease
HBOPLIAO_01662 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HBOPLIAO_01663 2.6e-160 aatB ET ABC transporter substrate-binding protein
HBOPLIAO_01664 1.6e-230 ymfF S Peptidase M16 inactive domain protein
HBOPLIAO_01665 3.2e-250 ymfH S Peptidase M16
HBOPLIAO_01666 7.4e-141 ymfM S Helix-turn-helix domain
HBOPLIAO_01667 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBOPLIAO_01668 2.9e-193 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBOPLIAO_01669 9e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HBOPLIAO_01671 0.0 L PLD-like domain
HBOPLIAO_01672 5.9e-89 mrr L restriction endonuclease
HBOPLIAO_01673 7.8e-152 L restriction endonuclease
HBOPLIAO_01674 1.2e-62 3.1.21.3 V Type I restriction modification DNA specificity domain
HBOPLIAO_01675 3.4e-177 L Belongs to the 'phage' integrase family
HBOPLIAO_01676 9.9e-28 hsdS-1 3.1.21.3 V Type I restriction modification DNA specificity domain
HBOPLIAO_01677 2.4e-153 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HBOPLIAO_01678 1.9e-280 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HBOPLIAO_01679 2e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HBOPLIAO_01680 3.4e-250 mmuP E amino acid
HBOPLIAO_01682 6.6e-262 S Putative peptidoglycan binding domain
HBOPLIAO_01683 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HBOPLIAO_01684 2.2e-87
HBOPLIAO_01685 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HBOPLIAO_01686 5.8e-214 yttB EGP Major facilitator Superfamily
HBOPLIAO_01687 8.2e-103
HBOPLIAO_01688 3e-24
HBOPLIAO_01689 5.1e-173 scrR K Transcriptional regulator, LacI family
HBOPLIAO_01690 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HBOPLIAO_01691 1.3e-96 yslB S Protein of unknown function (DUF2507)
HBOPLIAO_01692 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HBOPLIAO_01693 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HBOPLIAO_01694 4.4e-94 S Phosphoesterase
HBOPLIAO_01695 3.6e-76 ykuL S (CBS) domain
HBOPLIAO_01696 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HBOPLIAO_01697 3.4e-147 ykuT M mechanosensitive ion channel
HBOPLIAO_01698 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HBOPLIAO_01699 3.5e-26
HBOPLIAO_01700 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HBOPLIAO_01701 1.9e-181 ccpA K catabolite control protein A
HBOPLIAO_01702 1.9e-134
HBOPLIAO_01703 3.5e-132 yebC K Transcriptional regulatory protein
HBOPLIAO_01704 1.2e-133 mltD CBM50 M NlpC P60 family protein
HBOPLIAO_01705 5.7e-29
HBOPLIAO_01706 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HBOPLIAO_01707 9.8e-32 ykzG S Belongs to the UPF0356 family
HBOPLIAO_01708 2.4e-78
HBOPLIAO_01709 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HBOPLIAO_01710 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HBOPLIAO_01711 1.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HBOPLIAO_01712 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HBOPLIAO_01713 4.1e-275 lpdA 1.8.1.4 C Dehydrogenase
HBOPLIAO_01714 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HBOPLIAO_01715 3.3e-46 gcvH E glycine cleavage
HBOPLIAO_01716 4.1e-220 rodA D Belongs to the SEDS family
HBOPLIAO_01717 1e-31 S Protein of unknown function (DUF2969)
HBOPLIAO_01718 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HBOPLIAO_01719 6.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBOPLIAO_01720 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HBOPLIAO_01721 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HBOPLIAO_01722 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HBOPLIAO_01723 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HBOPLIAO_01724 8.9e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HBOPLIAO_01725 6.7e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HBOPLIAO_01726 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HBOPLIAO_01727 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HBOPLIAO_01728 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HBOPLIAO_01729 5e-232 pyrP F Permease
HBOPLIAO_01730 6.3e-129 yibF S overlaps another CDS with the same product name
HBOPLIAO_01731 9.9e-192 yibE S overlaps another CDS with the same product name
HBOPLIAO_01732 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBOPLIAO_01733 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HBOPLIAO_01734 1.6e-227 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HBOPLIAO_01735 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HBOPLIAO_01736 4.4e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HBOPLIAO_01737 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HBOPLIAO_01738 6e-108 tdk 2.7.1.21 F thymidine kinase
HBOPLIAO_01739 3.4e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HBOPLIAO_01740 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HBOPLIAO_01741 2.7e-223 arcD U Amino acid permease
HBOPLIAO_01742 2e-261 E Arginine ornithine antiporter
HBOPLIAO_01743 4.7e-79 argR K Regulates arginine biosynthesis genes
HBOPLIAO_01744 4.1e-239 arcA 3.5.3.6 E Arginine
HBOPLIAO_01745 3.9e-187 ampC V Beta-lactamase
HBOPLIAO_01746 1.1e-19
HBOPLIAO_01747 0.0 M domain protein
HBOPLIAO_01748 5.9e-91
HBOPLIAO_01749 5.1e-116 L Belongs to the 'phage' integrase family
HBOPLIAO_01750 8.7e-08 K Transcriptional regulator
HBOPLIAO_01751 3.6e-07 S Helix-turn-helix domain
HBOPLIAO_01754 8.5e-47 L Bifunctional DNA primase/polymerase, N-terminal
HBOPLIAO_01755 1.3e-90 S Phage plasmid primase, P4
HBOPLIAO_01758 4.1e-11 S head-tail joining protein
HBOPLIAO_01759 7.6e-31 L Phage-associated protein
HBOPLIAO_01760 4.1e-25 terS L Phage terminase, small subunit
HBOPLIAO_01761 2e-199 terL S overlaps another CDS with the same product name
HBOPLIAO_01762 1.1e-140 S Phage portal protein
HBOPLIAO_01763 1.2e-190 S Caudovirus prohead serine protease
HBOPLIAO_01764 5.7e-17 S Phage gp6-like head-tail connector protein
HBOPLIAO_01765 4.9e-24
HBOPLIAO_01766 6.2e-08
HBOPLIAO_01768 3.2e-159 yjcE P Sodium proton antiporter
HBOPLIAO_01769 1e-73 yjcE P Sodium proton antiporter
HBOPLIAO_01771 5.2e-56
HBOPLIAO_01773 4.5e-85
HBOPLIAO_01774 0.0 copA 3.6.3.54 P P-type ATPase
HBOPLIAO_01775 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HBOPLIAO_01776 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HBOPLIAO_01777 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HBOPLIAO_01778 1.2e-160 EG EamA-like transporter family
HBOPLIAO_01779 2.6e-180 comGA NU Type II IV secretion system protein
HBOPLIAO_01780 9.2e-113 comGB NU type II secretion system
HBOPLIAO_01781 2.6e-53 comGB NU type II secretion system
HBOPLIAO_01782 2.1e-46 comGC U competence protein ComGC
HBOPLIAO_01783 8.3e-78 NU general secretion pathway protein
HBOPLIAO_01784 2.7e-40
HBOPLIAO_01785 1e-45
HBOPLIAO_01787 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
HBOPLIAO_01788 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBOPLIAO_01789 2.2e-113 S Calcineurin-like phosphoesterase
HBOPLIAO_01790 1.3e-93 yutD S Protein of unknown function (DUF1027)
HBOPLIAO_01791 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HBOPLIAO_01792 2.4e-105 S Protein of unknown function (DUF1461)
HBOPLIAO_01793 5.5e-110 dedA S SNARE-like domain protein
HBOPLIAO_01794 5.4e-43
HBOPLIAO_01795 1.1e-75 KV of ABC transporters with duplicated ATPase domains
HBOPLIAO_01796 0.0 tetP J Elongation factor G, domain IV
HBOPLIAO_01798 3.8e-94 L Integrase
HBOPLIAO_01799 2.9e-42 relB L RelB antitoxin
HBOPLIAO_01800 6.8e-50 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HBOPLIAO_01802 5.4e-202
HBOPLIAO_01803 4.6e-41 rpmE2 J Ribosomal protein L31
HBOPLIAO_01804 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBOPLIAO_01805 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HBOPLIAO_01806 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HBOPLIAO_01807 3e-66 ywiB S Domain of unknown function (DUF1934)
HBOPLIAO_01808 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HBOPLIAO_01809 5e-270 ywfO S HD domain protein
HBOPLIAO_01810 2.7e-146 yxeH S hydrolase
HBOPLIAO_01811 2.1e-49
HBOPLIAO_01812 2.9e-96 S reductase
HBOPLIAO_01813 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HBOPLIAO_01814 3e-147 E Glyoxalase-like domain
HBOPLIAO_01815 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HBOPLIAO_01816 5.2e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HBOPLIAO_01817 5.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBOPLIAO_01818 4.4e-129 V ABC transporter
HBOPLIAO_01819 2.5e-212 bacI V MacB-like periplasmic core domain
HBOPLIAO_01820 2.4e-31 S CAAX protease self-immunity
HBOPLIAO_01821 3.1e-59
HBOPLIAO_01822 1.9e-204
HBOPLIAO_01824 3e-44
HBOPLIAO_01825 1.7e-33 S RelB antitoxin
HBOPLIAO_01826 3.1e-104 L Integrase
HBOPLIAO_01827 1.1e-38
HBOPLIAO_01828 3.3e-42 3.1.21.4 K sequence-specific DNA binding
HBOPLIAO_01829 3.7e-115 2.1.1.113, 2.1.1.37 L Belongs to the N(4) N(6)-methyltransferase family
HBOPLIAO_01831 1.3e-61 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBOPLIAO_01832 6e-109 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HBOPLIAO_01833 1.2e-255 nhaC C Na H antiporter NhaC
HBOPLIAO_01834 7.7e-38 S Cytochrome b5-like Heme/Steroid binding domain
HBOPLIAO_01835 4.8e-114 ywnB S NAD(P)H-binding
HBOPLIAO_01836 2.9e-37
HBOPLIAO_01837 2.5e-130 IQ Dehydrogenase reductase
HBOPLIAO_01838 5.8e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HBOPLIAO_01839 2.7e-68 L Belongs to the 'phage' integrase family
HBOPLIAO_01840 1e-101 ydeN S Serine hydrolase
HBOPLIAO_01841 1.1e-36 psiE S Phosphate-starvation-inducible E
HBOPLIAO_01842 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HBOPLIAO_01844 3.8e-176 S Aldo keto reductase
HBOPLIAO_01845 6.7e-35 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HBOPLIAO_01846 1.7e-96 L Helicase C-terminal domain protein
HBOPLIAO_01847 0.0 L Helicase C-terminal domain protein
HBOPLIAO_01848 5.5e-228 L COG3547 Transposase and inactivated derivatives
HBOPLIAO_01849 8.8e-65
HBOPLIAO_01850 1.7e-08 S Protein of unknown function, DUF536
HBOPLIAO_01852 4.5e-11 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
HBOPLIAO_01853 7.5e-11 L Resolvase, N terminal domain
HBOPLIAO_01854 1.2e-11
HBOPLIAO_01856 5.4e-37 L Resolvase, N terminal domain
HBOPLIAO_01857 2.2e-30 vsr L DNA mismatch endonuclease Vsr
HBOPLIAO_01858 3.1e-153 bepIM 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HBOPLIAO_01859 2.1e-231 tetL EGP Major Facilitator Superfamily
HBOPLIAO_01860 7.3e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HBOPLIAO_01861 1.2e-95 L Integrase
HBOPLIAO_01862 2e-53 S Phage derived protein Gp49-like (DUF891)
HBOPLIAO_01863 9.1e-38 K Helix-turn-helix domain
HBOPLIAO_01865 1.1e-202
HBOPLIAO_01866 1.5e-86
HBOPLIAO_01867 8.9e-67 pgaC GT2 M Glycosyl transferase
HBOPLIAO_01868 2.1e-45 pgaC GT2 M Glycosyl transferase
HBOPLIAO_01869 5.4e-92 pgaC GT2 M Glycosyl transferase
HBOPLIAO_01870 9.7e-141 T EAL domain
HBOPLIAO_01871 1.3e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
HBOPLIAO_01872 1.1e-64 yneR
HBOPLIAO_01873 1.2e-112 GM NAD(P)H-binding
HBOPLIAO_01874 6.1e-88 S membrane
HBOPLIAO_01875 2.1e-74 S membrane
HBOPLIAO_01876 1.3e-90 K Transcriptional regulator C-terminal region
HBOPLIAO_01877 3.2e-118 akr5f 1.1.1.346 S reductase
HBOPLIAO_01878 6.5e-28 akr5f 1.1.1.346 S reductase
HBOPLIAO_01879 4.3e-40 K Transcriptional regulator
HBOPLIAO_01880 5.5e-280 O Arylsulfotransferase (ASST)
HBOPLIAO_01881 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HBOPLIAO_01882 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBOPLIAO_01883 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HBOPLIAO_01884 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBOPLIAO_01885 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HBOPLIAO_01886 1.1e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HBOPLIAO_01887 9.8e-67 yabR J RNA binding
HBOPLIAO_01888 3.3e-56 divIC D Septum formation initiator
HBOPLIAO_01889 8.1e-39 yabO J S4 domain protein
HBOPLIAO_01890 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBOPLIAO_01891 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HBOPLIAO_01892 4e-113 S (CBS) domain
HBOPLIAO_01893 3.1e-147 tesE Q hydratase
HBOPLIAO_01894 1.8e-242 codA 3.5.4.1 F cytosine deaminase
HBOPLIAO_01895 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HBOPLIAO_01896 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
HBOPLIAO_01897 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBOPLIAO_01898 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HBOPLIAO_01900 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBOPLIAO_01901 3.7e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
HBOPLIAO_01902 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HBOPLIAO_01903 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HBOPLIAO_01904 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
HBOPLIAO_01905 3.7e-144 sprD D Domain of Unknown Function (DUF1542)
HBOPLIAO_01906 1.1e-126 L PFAM Integrase catalytic region
HBOPLIAO_01907 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HBOPLIAO_01908 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HBOPLIAO_01909 2.6e-158 htpX O Belongs to the peptidase M48B family
HBOPLIAO_01910 7e-93 lemA S LemA family
HBOPLIAO_01911 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBOPLIAO_01912 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
HBOPLIAO_01913 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HBOPLIAO_01914 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HBOPLIAO_01915 5.7e-157 3.2.1.55 GH51 G Right handed beta helix region
HBOPLIAO_01916 1.8e-200 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HBOPLIAO_01917 1.6e-138 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HBOPLIAO_01918 5.1e-125 srtA 3.4.22.70 M sortase family
HBOPLIAO_01919 1.3e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HBOPLIAO_01920 2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HBOPLIAO_01921 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HBOPLIAO_01922 4.4e-184 S Phosphotransferase system, EIIC
HBOPLIAO_01923 3.6e-123 L hmm pf00665
HBOPLIAO_01925 8e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HBOPLIAO_01926 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HBOPLIAO_01927 2.3e-105 O Zinc-dependent metalloprotease
HBOPLIAO_01928 6.8e-09 O Zinc-dependent metalloprotease
HBOPLIAO_01929 4.1e-115 S Membrane
HBOPLIAO_01930 1.5e-132 K Transcriptional regulatory protein, C-terminal domain protein
HBOPLIAO_01931 8.6e-159 pstS P Phosphate
HBOPLIAO_01932 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
HBOPLIAO_01933 4.7e-152 pstA P Phosphate transport system permease protein PstA
HBOPLIAO_01934 8.9e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HBOPLIAO_01935 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
HBOPLIAO_01936 2.7e-144
HBOPLIAO_01937 4.4e-118 ydaM M Glycosyl transferase
HBOPLIAO_01938 1.8e-35 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HBOPLIAO_01939 2.2e-280 hsdM 2.1.1.72 V type I restriction-modification system
HBOPLIAO_01940 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HBOPLIAO_01941 2.8e-140 IQ reductase
HBOPLIAO_01942 5.4e-57 yhaI S Protein of unknown function (DUF805)
HBOPLIAO_01943 2.2e-44
HBOPLIAO_01944 2.4e-22
HBOPLIAO_01945 3.2e-96 S PFAM Archaeal ATPase
HBOPLIAO_01946 6.3e-46
HBOPLIAO_01948 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HBOPLIAO_01949 7.9e-158 amtB P ammonium transporter
HBOPLIAO_01950 2.1e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HBOPLIAO_01951 1.4e-90 S B3 4 domain
HBOPLIAO_01952 2.1e-91
HBOPLIAO_01953 1.1e-74 pnb C nitroreductase
HBOPLIAO_01954 1.7e-53 ogt 2.1.1.63 L Methyltransferase
HBOPLIAO_01955 5.9e-121 L Belongs to the 'phage' integrase family
HBOPLIAO_01956 1.9e-10
HBOPLIAO_01962 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HBOPLIAO_01963 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HBOPLIAO_01964 1.8e-259 G Major Facilitator
HBOPLIAO_01965 4e-133 K Transcriptional regulator, LacI family
HBOPLIAO_01966 4.3e-54 gntT EG Gluconate
HBOPLIAO_01967 2.9e-182 K Transcriptional regulator, LacI family
HBOPLIAO_01968 2.7e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HBOPLIAO_01969 3.2e-95
HBOPLIAO_01970 2.1e-25
HBOPLIAO_01971 1.3e-61 asp S Asp23 family, cell envelope-related function
HBOPLIAO_01972 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HBOPLIAO_01974 7.9e-49
HBOPLIAO_01975 1.6e-67 yqkB S Belongs to the HesB IscA family
HBOPLIAO_01976 2.9e-82
HBOPLIAO_01977 6.2e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBOPLIAO_01978 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HBOPLIAO_01979 0.0 yjbQ P TrkA C-terminal domain protein
HBOPLIAO_01980 6.7e-278 pipD E Dipeptidase
HBOPLIAO_01981 4e-225 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HBOPLIAO_01982 1.1e-14 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HBOPLIAO_01983 1.2e-157 rssA S Phospholipase, patatin family
HBOPLIAO_01984 9.4e-118 L Integrase
HBOPLIAO_01985 5.5e-153 EG EamA-like transporter family
HBOPLIAO_01986 5.9e-191 V Beta-lactamase
HBOPLIAO_01987 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HBOPLIAO_01988 5e-122 yhiD S MgtC family
HBOPLIAO_01989 6.4e-39 S GyrI-like small molecule binding domain
HBOPLIAO_01990 2.7e-70 S GyrI-like small molecule binding domain
HBOPLIAO_01992 6.1e-117 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HBOPLIAO_01993 7.1e-50 azlD E Branched-chain amino acid transport
HBOPLIAO_01994 3.8e-76 azlC E azaleucine resistance protein AzlC
HBOPLIAO_01995 1.7e-207 yacL S domain protein
HBOPLIAO_01996 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HBOPLIAO_01997 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HBOPLIAO_01998 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HBOPLIAO_01999 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HBOPLIAO_02000 1.5e-266 pepC 3.4.22.40 E Peptidase C1-like family
HBOPLIAO_02001 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HBOPLIAO_02002 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HBOPLIAO_02003 2.4e-119 tcyB E ABC transporter
HBOPLIAO_02004 9.4e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HBOPLIAO_02005 3.1e-169 I alpha/beta hydrolase fold
HBOPLIAO_02006 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBOPLIAO_02007 0.0 S Bacterial membrane protein, YfhO
HBOPLIAO_02008 3.8e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HBOPLIAO_02009 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HBOPLIAO_02011 2.1e-84 ydcK S Belongs to the SprT family
HBOPLIAO_02012 0.0 yhgF K Tex-like protein N-terminal domain protein
HBOPLIAO_02013 5.1e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HBOPLIAO_02014 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HBOPLIAO_02015 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
HBOPLIAO_02016 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HBOPLIAO_02017 9.5e-300 aspT P Predicted Permease Membrane Region
HBOPLIAO_02018 2.8e-252 EGP Major facilitator Superfamily
HBOPLIAO_02019 5.5e-110
HBOPLIAO_02022 1.4e-158 yjjH S Calcineurin-like phosphoesterase
HBOPLIAO_02023 6.5e-263 dtpT U amino acid peptide transporter
HBOPLIAO_02024 3.7e-19
HBOPLIAO_02026 5.8e-50 yqiG C Oxidoreductase
HBOPLIAO_02027 5e-19 yqiG C Oxidoreductase
HBOPLIAO_02028 1.1e-50 yqiG C Oxidoreductase
HBOPLIAO_02029 8.5e-54 S macrophage migration inhibitory factor
HBOPLIAO_02030 1.2e-64 K HxlR-like helix-turn-helix
HBOPLIAO_02031 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HBOPLIAO_02033 1.9e-225 L Transposase IS66 family
HBOPLIAO_02035 3.5e-24
HBOPLIAO_02036 1e-73
HBOPLIAO_02037 1.8e-226 clcA_2 P Chloride transporter, ClC family
HBOPLIAO_02038 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HBOPLIAO_02039 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
HBOPLIAO_02041 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HBOPLIAO_02043 1.2e-100 nqr 1.5.1.36 S reductase
HBOPLIAO_02044 6.1e-198 XK27_09615 S reductase
HBOPLIAO_02045 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HBOPLIAO_02046 2.1e-91
HBOPLIAO_02047 6.7e-66 K Transcriptional regulator, HxlR family
HBOPLIAO_02048 2.4e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HBOPLIAO_02049 3.8e-146 epsB M biosynthesis protein
HBOPLIAO_02050 8.5e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HBOPLIAO_02051 2.6e-115 rfbP M Bacterial sugar transferase
HBOPLIAO_02052 5.1e-70 L Integrase
HBOPLIAO_02053 4e-126 S KAP family P-loop domain
HBOPLIAO_02054 7.4e-19
HBOPLIAO_02055 1.8e-12 S Domain of unknown function (DUF4145)
HBOPLIAO_02056 8.4e-84 KT Putative sugar diacid recognition
HBOPLIAO_02057 1.7e-219 EG GntP family permease
HBOPLIAO_02058 3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HBOPLIAO_02059 7.7e-58
HBOPLIAO_02061 6.2e-30 pre D plasmid recombination enzyme
HBOPLIAO_02062 1.9e-113 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HBOPLIAO_02063 1.7e-50 S Plasmid replication protein
HBOPLIAO_02065 6e-93 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
HBOPLIAO_02066 1.5e-16 pre D plasmid recombination enzyme
HBOPLIAO_02067 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HBOPLIAO_02068 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HBOPLIAO_02069 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HBOPLIAO_02070 3e-203 coiA 3.6.4.12 S Competence protein
HBOPLIAO_02071 1.7e-262 pipD E Dipeptidase
HBOPLIAO_02072 6.7e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBOPLIAO_02073 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBOPLIAO_02074 5.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HBOPLIAO_02075 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HBOPLIAO_02076 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HBOPLIAO_02077 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HBOPLIAO_02078 7.5e-61 L Resolvase, N terminal domain
HBOPLIAO_02079 2.7e-127 tesE Q hydratase
HBOPLIAO_02080 2e-116 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HBOPLIAO_02082 3.2e-171 XK27_00915 C Luciferase-like monooxygenase
HBOPLIAO_02083 5.7e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HBOPLIAO_02084 7.3e-69 S Protein of unknown function (DUF3021)
HBOPLIAO_02085 6.4e-78 K LytTr DNA-binding domain
HBOPLIAO_02086 9.1e-92 K Acetyltransferase (GNAT) family
HBOPLIAO_02087 4.8e-07 cnrT EG EamA-like transporter family
HBOPLIAO_02088 9.8e-51 S Domain of unknown function (DUF4430)
HBOPLIAO_02089 5.9e-73 S ECF transporter, substrate-specific component
HBOPLIAO_02090 2.9e-19 S PFAM Archaeal ATPase
HBOPLIAO_02091 1.9e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HBOPLIAO_02092 1.7e-17 K Winged helix DNA-binding domain
HBOPLIAO_02093 3.7e-286 lmrA V ABC transporter, ATP-binding protein
HBOPLIAO_02094 0.0 yfiC V ABC transporter
HBOPLIAO_02095 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HBOPLIAO_02096 2.6e-269 pipD E Dipeptidase
HBOPLIAO_02097 1.3e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBOPLIAO_02098 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
HBOPLIAO_02099 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HBOPLIAO_02100 1e-243 yagE E amino acid
HBOPLIAO_02101 1.7e-139 aroD S Serine hydrolase (FSH1)
HBOPLIAO_02102 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
HBOPLIAO_02103 5.2e-167 GK ROK family
HBOPLIAO_02104 0.0 tetP J elongation factor G
HBOPLIAO_02105 5.1e-81 uspA T universal stress protein
HBOPLIAO_02106 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
HBOPLIAO_02107 7.1e-63
HBOPLIAO_02108 3.1e-14
HBOPLIAO_02109 1.4e-212 EGP Major facilitator Superfamily
HBOPLIAO_02110 1.3e-257 G PTS system Galactitol-specific IIC component
HBOPLIAO_02111 2.6e-180 1.6.5.5 C Zinc-binding dehydrogenase
HBOPLIAO_02112 1.1e-161
HBOPLIAO_02113 1e-72 K Transcriptional regulator
HBOPLIAO_02114 3.7e-190 D Alpha beta
HBOPLIAO_02115 2.2e-52 ypaA S Protein of unknown function (DUF1304)
HBOPLIAO_02116 0.0 yjcE P Sodium proton antiporter
HBOPLIAO_02117 1.6e-52 yvlA
HBOPLIAO_02118 1.8e-113 P Cobalt transport protein
HBOPLIAO_02119 1e-246 cbiO1 S ABC transporter, ATP-binding protein
HBOPLIAO_02120 3e-96 S ABC-type cobalt transport system, permease component
HBOPLIAO_02121 3.3e-133 S membrane transporter protein
HBOPLIAO_02122 2.5e-138 IQ KR domain
HBOPLIAO_02123 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
HBOPLIAO_02124 4.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)