ORF_ID e_value Gene_name EC_number CAZy COGs Description
IGGGJKIG_00001 1.8e-12 S Domain of unknown function (DUF4145)
IGGGJKIG_00002 7.4e-19
IGGGJKIG_00003 6.6e-109 S KAP family P-loop domain
IGGGJKIG_00004 7.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IGGGJKIG_00005 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IGGGJKIG_00006 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
IGGGJKIG_00007 4e-113 yjbH Q Thioredoxin
IGGGJKIG_00008 1.2e-78 2.7.13.3 T GHKL domain
IGGGJKIG_00011 3.7e-260 S Putative peptidoglycan binding domain
IGGGJKIG_00012 3.5e-35
IGGGJKIG_00013 2.3e-228 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IGGGJKIG_00014 1.7e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IGGGJKIG_00015 1.6e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IGGGJKIG_00016 3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IGGGJKIG_00017 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IGGGJKIG_00018 2.2e-93 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IGGGJKIG_00019 7.1e-101 ydaM M Glycosyl transferase family group 2
IGGGJKIG_00020 3.4e-224 G Glycosyl hydrolases family 8
IGGGJKIG_00021 1.3e-122 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IGGGJKIG_00022 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
IGGGJKIG_00023 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IGGGJKIG_00024 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IGGGJKIG_00025 5.5e-45 yitW S Pfam:DUF59
IGGGJKIG_00026 1e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IGGGJKIG_00027 0.0 lacS G Transporter
IGGGJKIG_00028 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IGGGJKIG_00029 4.4e-184 S Phosphotransferase system, EIIC
IGGGJKIG_00030 4.8e-07 cnrT EG EamA-like transporter family
IGGGJKIG_00031 9.8e-51 S Domain of unknown function (DUF4430)
IGGGJKIG_00032 5.9e-73 S ECF transporter, substrate-specific component
IGGGJKIG_00033 2.9e-19 S PFAM Archaeal ATPase
IGGGJKIG_00034 1.9e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGGGJKIG_00035 1.7e-17 K Winged helix DNA-binding domain
IGGGJKIG_00036 3.7e-286 lmrA V ABC transporter, ATP-binding protein
IGGGJKIG_00037 0.0 yfiC V ABC transporter
IGGGJKIG_00038 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
IGGGJKIG_00039 2.6e-269 pipD E Dipeptidase
IGGGJKIG_00040 1.3e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IGGGJKIG_00041 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
IGGGJKIG_00042 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IGGGJKIG_00043 2.7e-244 yagE E amino acid
IGGGJKIG_00044 1.7e-139 aroD S Serine hydrolase (FSH1)
IGGGJKIG_00045 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
IGGGJKIG_00046 5.2e-167 GK ROK family
IGGGJKIG_00047 0.0 tetP J elongation factor G
IGGGJKIG_00048 5.1e-81 uspA T universal stress protein
IGGGJKIG_00049 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
IGGGJKIG_00050 7.1e-63
IGGGJKIG_00051 3.1e-14
IGGGJKIG_00052 1.4e-212 EGP Major facilitator Superfamily
IGGGJKIG_00053 1.3e-257 G PTS system Galactitol-specific IIC component
IGGGJKIG_00054 2.6e-180 1.6.5.5 C Zinc-binding dehydrogenase
IGGGJKIG_00055 1.1e-161
IGGGJKIG_00056 1e-72 K Transcriptional regulator
IGGGJKIG_00057 3.7e-190 D Alpha beta
IGGGJKIG_00058 2.2e-52 ypaA S Protein of unknown function (DUF1304)
IGGGJKIG_00059 0.0 yjcE P Sodium proton antiporter
IGGGJKIG_00060 1.6e-52 yvlA
IGGGJKIG_00061 1.8e-113 P Cobalt transport protein
IGGGJKIG_00062 1.9e-245 cbiO1 S ABC transporter, ATP-binding protein
IGGGJKIG_00063 3e-96 S ABC-type cobalt transport system, permease component
IGGGJKIG_00064 3.3e-133 S membrane transporter protein
IGGGJKIG_00065 2.5e-138 IQ KR domain
IGGGJKIG_00066 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
IGGGJKIG_00067 4.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IGGGJKIG_00069 3.1e-57 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IGGGJKIG_00070 2.7e-20
IGGGJKIG_00072 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
IGGGJKIG_00073 2.4e-281 L Transposase IS66 family
IGGGJKIG_00074 1.6e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IGGGJKIG_00076 3.2e-236 L Integrase core domain
IGGGJKIG_00077 3.4e-132 O Bacterial dnaA protein
IGGGJKIG_00078 2.7e-26 K TRANSCRIPTIONal
IGGGJKIG_00080 1.5e-43 pldB 3.1.1.5 I Serine aminopeptidase, S33
IGGGJKIG_00099 5.7e-172
IGGGJKIG_00100 1.1e-72
IGGGJKIG_00101 3.7e-140 bamA GM domain, Protein
IGGGJKIG_00102 2.1e-41 ybaN S Protein of unknown function (DUF454)
IGGGJKIG_00103 3.1e-72 S Protein of unknown function (DUF3290)
IGGGJKIG_00104 6.2e-114 yviA S Protein of unknown function (DUF421)
IGGGJKIG_00105 1.2e-37 azlC E azaleucine resistance protein AzlC
IGGGJKIG_00106 7.3e-60 K Aminotransferase class I and II
IGGGJKIG_00107 2e-152 K Aminotransferase class I and II
IGGGJKIG_00108 3.6e-288 S amidohydrolase
IGGGJKIG_00110 1.8e-161 S reductase
IGGGJKIG_00111 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
IGGGJKIG_00112 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IGGGJKIG_00113 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
IGGGJKIG_00114 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IGGGJKIG_00115 0.0 asnB 6.3.5.4 E Asparagine synthase
IGGGJKIG_00116 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IGGGJKIG_00117 4.3e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IGGGJKIG_00118 9.7e-130 jag S R3H domain protein
IGGGJKIG_00119 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IGGGJKIG_00120 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IGGGJKIG_00121 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IGGGJKIG_00122 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IGGGJKIG_00123 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IGGGJKIG_00124 3.3e-82 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
IGGGJKIG_00125 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
IGGGJKIG_00126 1.7e-34 yaaA S S4 domain protein YaaA
IGGGJKIG_00127 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IGGGJKIG_00128 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGGGJKIG_00129 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IGGGJKIG_00130 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
IGGGJKIG_00131 1.4e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IGGGJKIG_00132 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IGGGJKIG_00133 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IGGGJKIG_00134 2e-74 rplI J Binds to the 23S rRNA
IGGGJKIG_00135 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IGGGJKIG_00136 1.3e-205 yttB EGP Major facilitator Superfamily
IGGGJKIG_00137 3.7e-54
IGGGJKIG_00138 2e-155 S Polyphosphate nucleotide phosphotransferase, PPK2 family
IGGGJKIG_00139 3.7e-08 K DNA-binding helix-turn-helix protein
IGGGJKIG_00140 9e-125 O Bacterial dnaA protein
IGGGJKIG_00141 3.5e-214 L Integrase core domain
IGGGJKIG_00142 1.3e-125 G Peptidase_C39 like family
IGGGJKIG_00143 2.1e-25
IGGGJKIG_00144 9.5e-30
IGGGJKIG_00145 1.3e-102 K DNA-templated transcription, initiation
IGGGJKIG_00146 8.1e-35
IGGGJKIG_00147 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
IGGGJKIG_00148 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IGGGJKIG_00149 2.2e-229 L transposase, IS605 OrfB family
IGGGJKIG_00150 8.1e-238 L Transposase
IGGGJKIG_00151 3.5e-24
IGGGJKIG_00152 1e-73
IGGGJKIG_00153 2e-263 L PFAM Integrase catalytic region
IGGGJKIG_00154 5.1e-70 L Integrase
IGGGJKIG_00155 2.8e-162 yueF S AI-2E family transporter
IGGGJKIG_00157 1.9e-225 L Transposase IS66 family
IGGGJKIG_00159 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IGGGJKIG_00160 1.2e-64 K HxlR-like helix-turn-helix
IGGGJKIG_00161 8.5e-54 S macrophage migration inhibitory factor
IGGGJKIG_00162 1.1e-50 yqiG C Oxidoreductase
IGGGJKIG_00163 5e-19 yqiG C Oxidoreductase
IGGGJKIG_00164 5.8e-50 yqiG C Oxidoreductase
IGGGJKIG_00166 3.7e-19
IGGGJKIG_00167 6.5e-263 dtpT U amino acid peptide transporter
IGGGJKIG_00168 1.4e-158 yjjH S Calcineurin-like phosphoesterase
IGGGJKIG_00171 5.5e-110
IGGGJKIG_00172 2.8e-252 EGP Major facilitator Superfamily
IGGGJKIG_00173 9.5e-300 aspT P Predicted Permease Membrane Region
IGGGJKIG_00174 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IGGGJKIG_00175 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
IGGGJKIG_00176 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IGGGJKIG_00177 5.1e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IGGGJKIG_00178 0.0 yhgF K Tex-like protein N-terminal domain protein
IGGGJKIG_00179 2.1e-84 ydcK S Belongs to the SprT family
IGGGJKIG_00181 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IGGGJKIG_00182 3.8e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IGGGJKIG_00183 0.0 S Bacterial membrane protein, YfhO
IGGGJKIG_00184 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IGGGJKIG_00185 3.1e-169 I alpha/beta hydrolase fold
IGGGJKIG_00186 9.4e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IGGGJKIG_00187 2.4e-119 tcyB E ABC transporter
IGGGJKIG_00188 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IGGGJKIG_00189 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IGGGJKIG_00190 1.5e-266 pepC 3.4.22.40 E Peptidase C1-like family
IGGGJKIG_00191 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IGGGJKIG_00192 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
IGGGJKIG_00193 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IGGGJKIG_00194 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IGGGJKIG_00195 1.7e-207 yacL S domain protein
IGGGJKIG_00196 2.1e-126
IGGGJKIG_00197 3.6e-54 S Sugar efflux transporter for intercellular exchange
IGGGJKIG_00198 1.5e-36 sugE U Multidrug resistance protein
IGGGJKIG_00199 3e-23
IGGGJKIG_00200 1.3e-38 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IGGGJKIG_00201 2.6e-38 higA K Helix-turn-helix XRE-family like proteins
IGGGJKIG_00202 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IGGGJKIG_00203 1.9e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IGGGJKIG_00204 2.9e-33 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IGGGJKIG_00206 2.4e-175 L Integrase core domain
IGGGJKIG_00207 3.9e-27 mleP3 S Membrane transport protein
IGGGJKIG_00208 1.7e-68 T Transcriptional regulatory protein, C terminal
IGGGJKIG_00209 1.5e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IGGGJKIG_00210 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IGGGJKIG_00211 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IGGGJKIG_00212 2.4e-223 mdtG EGP Major facilitator Superfamily
IGGGJKIG_00213 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
IGGGJKIG_00214 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IGGGJKIG_00217 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IGGGJKIG_00218 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IGGGJKIG_00219 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
IGGGJKIG_00220 0.0 trxB2 1.8.1.9 C Thioredoxin domain
IGGGJKIG_00221 4.4e-181 M LPXTG-motif cell wall anchor domain protein
IGGGJKIG_00222 0.0 M LPXTG-motif cell wall anchor domain protein
IGGGJKIG_00223 1.2e-23 M LPXTG-motif cell wall anchor domain protein
IGGGJKIG_00224 1.8e-11 sraP UW domain, Protein
IGGGJKIG_00225 2.6e-191 nss M transferase activity, transferring glycosyl groups
IGGGJKIG_00226 3.1e-143 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
IGGGJKIG_00227 2.6e-195 M transferase activity, transferring glycosyl groups
IGGGJKIG_00228 5.3e-217 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
IGGGJKIG_00229 1.7e-154 asp3 S Accessory Sec secretory system ASP3
IGGGJKIG_00230 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IGGGJKIG_00231 1.9e-225 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IGGGJKIG_00232 7.9e-196 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IGGGJKIG_00236 7e-08 UW Hep Hag repeat protein
IGGGJKIG_00237 9.2e-178 L PFAM Integrase catalytic region
IGGGJKIG_00238 1.8e-132 L PFAM Integrase catalytic region
IGGGJKIG_00243 2.2e-38 L Belongs to the 'phage' integrase family
IGGGJKIG_00244 1.3e-114 XK27_04590 S NADPH-dependent FMN reductase
IGGGJKIG_00245 2.2e-73 fld C Flavodoxin
IGGGJKIG_00246 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
IGGGJKIG_00247 5.9e-68 P Cadmium resistance transporter
IGGGJKIG_00248 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
IGGGJKIG_00249 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
IGGGJKIG_00250 3e-54 pduU E BMC
IGGGJKIG_00251 1.1e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IGGGJKIG_00252 4.3e-203 pduQ C Iron-containing alcohol dehydrogenase
IGGGJKIG_00253 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
IGGGJKIG_00254 1.1e-78 pduO S Haem-degrading
IGGGJKIG_00255 7e-104 pduO 2.5.1.17 S Cobalamin adenosyltransferase
IGGGJKIG_00256 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
IGGGJKIG_00257 1.3e-79 S Putative propanediol utilisation
IGGGJKIG_00258 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
IGGGJKIG_00259 7.8e-40 pduA_4 CQ BMC
IGGGJKIG_00260 3.6e-57 pduK CQ BMC
IGGGJKIG_00261 8.1e-45 pduH S Dehydratase medium subunit
IGGGJKIG_00262 3.1e-307 pduG D Diol dehydratase reactivase ATPase-like domain
IGGGJKIG_00263 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
IGGGJKIG_00264 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
IGGGJKIG_00265 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
IGGGJKIG_00266 2.7e-134 pduB E BMC
IGGGJKIG_00267 1.6e-37 pduA_4 CQ BMC
IGGGJKIG_00268 8.3e-159 K helix_turn_helix, arabinose operon control protein
IGGGJKIG_00269 3.6e-138 eutJ E Hsp70 protein
IGGGJKIG_00270 1.9e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IGGGJKIG_00271 3.2e-95
IGGGJKIG_00272 6.4e-127 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IGGGJKIG_00273 5.9e-152 S AI-2E family transporter
IGGGJKIG_00274 5.2e-133 XK27_07210 6.1.1.6 S B3 4 domain
IGGGJKIG_00275 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
IGGGJKIG_00276 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
IGGGJKIG_00277 4.8e-88 GM epimerase
IGGGJKIG_00278 4.9e-154 ypdB V (ABC) transporter
IGGGJKIG_00279 6.8e-240 yhdP S Transporter associated domain
IGGGJKIG_00280 9.9e-85 nrdI F Belongs to the NrdI family
IGGGJKIG_00281 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
IGGGJKIG_00282 3.1e-193 yeaN P Transporter, major facilitator family protein
IGGGJKIG_00283 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IGGGJKIG_00284 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IGGGJKIG_00285 1.7e-130 K LysR substrate binding domain
IGGGJKIG_00286 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IGGGJKIG_00287 3.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IGGGJKIG_00288 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IGGGJKIG_00289 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IGGGJKIG_00290 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IGGGJKIG_00291 9.6e-115 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
IGGGJKIG_00292 6.7e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IGGGJKIG_00293 4.2e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IGGGJKIG_00294 4.9e-177 K AI-2E family transporter
IGGGJKIG_00295 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IGGGJKIG_00296 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IGGGJKIG_00297 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IGGGJKIG_00298 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IGGGJKIG_00299 4.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IGGGJKIG_00300 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IGGGJKIG_00301 5.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IGGGJKIG_00302 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGGGJKIG_00303 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGGGJKIG_00304 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IGGGJKIG_00305 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IGGGJKIG_00306 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IGGGJKIG_00307 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IGGGJKIG_00308 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IGGGJKIG_00309 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
IGGGJKIG_00310 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IGGGJKIG_00311 9.7e-173
IGGGJKIG_00312 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IGGGJKIG_00314 9.1e-75 M PFAM NLP P60 protein
IGGGJKIG_00315 2.2e-182 ABC-SBP S ABC transporter
IGGGJKIG_00316 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IGGGJKIG_00317 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
IGGGJKIG_00318 4.5e-92 P Cadmium resistance transporter
IGGGJKIG_00319 6.8e-56 K Transcriptional regulator, ArsR family
IGGGJKIG_00320 5.5e-55 M Leucine-rich repeat (LRR) protein
IGGGJKIG_00321 1.6e-236 mepA V MATE efflux family protein
IGGGJKIG_00322 2.1e-54 trxA O Belongs to the thioredoxin family
IGGGJKIG_00323 6.6e-131 terC P membrane
IGGGJKIG_00324 1.3e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IGGGJKIG_00325 2.2e-168 corA P CorA-like Mg2+ transporter protein
IGGGJKIG_00326 1.6e-305 L Transposase
IGGGJKIG_00327 1.4e-283 pipD E Dipeptidase
IGGGJKIG_00328 1.6e-241 pbuX F xanthine permease
IGGGJKIG_00329 1.8e-251 nhaC C Na H antiporter NhaC
IGGGJKIG_00330 4e-240 S C4-dicarboxylate anaerobic carrier
IGGGJKIG_00331 1.1e-27 S C4-dicarboxylate anaerobic carrier
IGGGJKIG_00332 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
IGGGJKIG_00333 1.3e-41
IGGGJKIG_00334 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IGGGJKIG_00335 3.8e-207 gldA 1.1.1.6 C dehydrogenase
IGGGJKIG_00336 4.7e-125 S Alpha beta hydrolase
IGGGJKIG_00337 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IGGGJKIG_00338 2.5e-101
IGGGJKIG_00340 1.4e-124 yciB M ErfK YbiS YcfS YnhG
IGGGJKIG_00341 1.9e-139 ynjE 2.8.1.11 P Rhodanese Homology Domain
IGGGJKIG_00342 3e-15 yeeD O Belongs to the sulfur carrier protein TusA family
IGGGJKIG_00343 2.1e-123 XK27_00825 S Sulfite exporter TauE/SafE
IGGGJKIG_00344 5.2e-40 yedF O Belongs to the sulfur carrier protein TusA family
IGGGJKIG_00345 1.3e-181 yedE S Sulphur transport
IGGGJKIG_00346 1.1e-160 selA 2.9.1.1 H Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
IGGGJKIG_00347 1.4e-159 sufS 2.8.1.7, 4.4.1.16 E Beta-eliminating lyase
IGGGJKIG_00348 1.1e-232 selB J Elongation factor SelB, winged helix
IGGGJKIG_00349 4.7e-28 S Protein of unknown function (DUF3343)
IGGGJKIG_00350 2.3e-79 yedF O Belongs to the sulfur carrier protein TusA family
IGGGJKIG_00351 1.1e-157 selD 2.7.9.3 H Synthesizes selenophosphate from selenide and ATP
IGGGJKIG_00352 1.9e-124 XK27_00825 S Sulfite exporter TauE/SafE
IGGGJKIG_00353 2.6e-170 5.1.1.4 E Proline racemase
IGGGJKIG_00354 2.8e-74 3.5.1.1 EJ Glycine/sarcosine/betaine reductase component B subunits
IGGGJKIG_00355 2.6e-111 prdD S An automated process has identified a potential problem with this gene model
IGGGJKIG_00356 1.9e-31 S the current gene model (or a revised gene model) may contain a premature stop
IGGGJKIG_00357 1.8e-75 prdB 1.21.4.1, 1.21.4.2 S the current gene model (or a revised gene model) may contain a premature stop
IGGGJKIG_00358 1.1e-50 S Psort location Cytoplasmic, score
IGGGJKIG_00359 4e-310 prdA 1.21.4.1 EJ Glycine/sarcosine/betaine reductase component B subunits
IGGGJKIG_00360 8.6e-138 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
IGGGJKIG_00362 7e-201 dtpT P POT family
IGGGJKIG_00363 7.1e-221 rnfC C RnfC Barrel sandwich hybrid domain
IGGGJKIG_00364 1.6e-21
IGGGJKIG_00365 5.4e-47
IGGGJKIG_00366 1.9e-95 K Acetyltransferase (GNAT) domain
IGGGJKIG_00367 8.5e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IGGGJKIG_00368 2.2e-146 gntT EG Gluconate
IGGGJKIG_00369 2.1e-65 gntT EG Gluconate
IGGGJKIG_00370 9.9e-183 K Transcriptional regulator, LacI family
IGGGJKIG_00371 6.3e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IGGGJKIG_00372 4.2e-95
IGGGJKIG_00373 2.8e-25
IGGGJKIG_00374 1.3e-61 asp S Asp23 family, cell envelope-related function
IGGGJKIG_00375 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IGGGJKIG_00377 2.7e-49
IGGGJKIG_00378 9.1e-68 yqkB S Belongs to the HesB IscA family
IGGGJKIG_00379 4.3e-86 uspA T Belongs to the universal stress protein A family
IGGGJKIG_00380 2.1e-276 pepV 3.5.1.18 E dipeptidase PepV
IGGGJKIG_00381 6.5e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IGGGJKIG_00382 4.1e-303 ytgP S Polysaccharide biosynthesis protein
IGGGJKIG_00383 4.9e-41
IGGGJKIG_00384 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IGGGJKIG_00385 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IGGGJKIG_00386 9.6e-92 tag 3.2.2.20 L glycosylase
IGGGJKIG_00387 1.5e-253 EGP Major facilitator Superfamily
IGGGJKIG_00388 4.3e-85 perR P Belongs to the Fur family
IGGGJKIG_00389 6.3e-233 cycA E Amino acid permease
IGGGJKIG_00390 2.8e-102 V VanZ like family
IGGGJKIG_00391 1e-23
IGGGJKIG_00392 6.7e-82 S Short repeat of unknown function (DUF308)
IGGGJKIG_00393 2.9e-78 S Psort location Cytoplasmic, score
IGGGJKIG_00394 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
IGGGJKIG_00395 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
IGGGJKIG_00396 8.1e-154 yeaE S Aldo keto
IGGGJKIG_00397 2.3e-93 lytE M LysM domain protein
IGGGJKIG_00398 0.0 oppD EP Psort location Cytoplasmic, score
IGGGJKIG_00399 3.3e-80 lytE M LysM domain protein
IGGGJKIG_00400 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
IGGGJKIG_00401 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IGGGJKIG_00402 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IGGGJKIG_00403 1.5e-237 lmrB EGP Major facilitator Superfamily
IGGGJKIG_00404 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
IGGGJKIG_00412 4.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IGGGJKIG_00413 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
IGGGJKIG_00414 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IGGGJKIG_00415 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IGGGJKIG_00416 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IGGGJKIG_00417 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
IGGGJKIG_00418 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IGGGJKIG_00419 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IGGGJKIG_00420 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
IGGGJKIG_00421 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IGGGJKIG_00422 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IGGGJKIG_00423 1.9e-109 L Transposase
IGGGJKIG_00424 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IGGGJKIG_00425 2.4e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IGGGJKIG_00426 5.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IGGGJKIG_00427 3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IGGGJKIG_00428 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IGGGJKIG_00429 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IGGGJKIG_00430 2.6e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IGGGJKIG_00431 9.3e-130 IQ reductase
IGGGJKIG_00432 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IGGGJKIG_00433 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IGGGJKIG_00434 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IGGGJKIG_00435 4.2e-77 marR K Transcriptional regulator, MarR family
IGGGJKIG_00436 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IGGGJKIG_00438 2.8e-199 xerS L Belongs to the 'phage' integrase family
IGGGJKIG_00439 1.2e-133 mltD CBM50 M NlpC P60 family protein
IGGGJKIG_00440 5.7e-29
IGGGJKIG_00441 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
IGGGJKIG_00442 9.8e-32 ykzG S Belongs to the UPF0356 family
IGGGJKIG_00443 2.4e-78
IGGGJKIG_00444 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IGGGJKIG_00445 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IGGGJKIG_00446 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IGGGJKIG_00447 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IGGGJKIG_00448 4.1e-275 lpdA 1.8.1.4 C Dehydrogenase
IGGGJKIG_00449 5.6e-261 S Uncharacterised protein family (UPF0236)
IGGGJKIG_00450 1.6e-52 azlD S branched-chain amino acid
IGGGJKIG_00451 3.7e-136 azlC E AzlC protein
IGGGJKIG_00452 6.5e-199 hpk31 2.7.13.3 T Histidine kinase
IGGGJKIG_00453 1.2e-123 K response regulator
IGGGJKIG_00454 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IGGGJKIG_00455 9.5e-172 deoR K sugar-binding domain protein
IGGGJKIG_00456 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IGGGJKIG_00457 7.9e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
IGGGJKIG_00458 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IGGGJKIG_00459 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IGGGJKIG_00460 7.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
IGGGJKIG_00461 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IGGGJKIG_00462 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
IGGGJKIG_00463 1.7e-154 spo0J K Belongs to the ParB family
IGGGJKIG_00464 3.9e-139 soj D Sporulation initiation inhibitor
IGGGJKIG_00465 4.3e-151 noc K Belongs to the ParB family
IGGGJKIG_00466 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IGGGJKIG_00467 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
IGGGJKIG_00468 5.6e-169 rihC 3.2.2.1 F Nucleoside
IGGGJKIG_00469 3.3e-217 nupG F Nucleoside transporter
IGGGJKIG_00470 7.2e-221 cycA E Amino acid permease
IGGGJKIG_00472 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IGGGJKIG_00473 1.2e-264 glnP P ABC transporter
IGGGJKIG_00474 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IGGGJKIG_00475 2.5e-158 L hmm pf00665
IGGGJKIG_00476 3.6e-74 L Helix-turn-helix domain
IGGGJKIG_00477 2.3e-08 L Helix-turn-helix domain
IGGGJKIG_00479 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IGGGJKIG_00480 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IGGGJKIG_00481 9e-119 S Repeat protein
IGGGJKIG_00482 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IGGGJKIG_00483 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IGGGJKIG_00484 1.3e-57 XK27_04120 S Putative amino acid metabolism
IGGGJKIG_00485 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
IGGGJKIG_00486 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IGGGJKIG_00488 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IGGGJKIG_00489 4.2e-32 cspA K Cold shock protein
IGGGJKIG_00490 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IGGGJKIG_00491 1.9e-42 divIVA D DivIVA domain protein
IGGGJKIG_00492 5.1e-142 ylmH S S4 domain protein
IGGGJKIG_00493 3.2e-40 yggT S YGGT family
IGGGJKIG_00494 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IGGGJKIG_00495 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IGGGJKIG_00496 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IGGGJKIG_00497 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IGGGJKIG_00498 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IGGGJKIG_00499 2.9e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IGGGJKIG_00500 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IGGGJKIG_00501 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IGGGJKIG_00502 2.6e-56 ftsL D Cell division protein FtsL
IGGGJKIG_00503 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IGGGJKIG_00504 3.1e-77 mraZ K Belongs to the MraZ family
IGGGJKIG_00505 7.3e-56
IGGGJKIG_00506 1.2e-10 S Protein of unknown function (DUF4044)
IGGGJKIG_00507 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IGGGJKIG_00508 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IGGGJKIG_00509 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
IGGGJKIG_00510 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IGGGJKIG_00512 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
IGGGJKIG_00513 7.8e-296 L Transposase IS66 family
IGGGJKIG_00514 2.9e-15
IGGGJKIG_00515 1.1e-119 ybhL S Belongs to the BI1 family
IGGGJKIG_00516 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
IGGGJKIG_00517 9.3e-197 S Protein of unknown function (DUF3114)
IGGGJKIG_00518 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IGGGJKIG_00519 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IGGGJKIG_00520 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
IGGGJKIG_00521 9.1e-62 S Domain of unknown function (DUF4828)
IGGGJKIG_00522 4.5e-191 mocA S Oxidoreductase
IGGGJKIG_00523 8.5e-227 yfmL L DEAD DEAH box helicase
IGGGJKIG_00525 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IGGGJKIG_00526 9.3e-56
IGGGJKIG_00527 2.3e-67 gtcA S Teichoic acid glycosylation protein
IGGGJKIG_00528 1.5e-77 fld C Flavodoxin
IGGGJKIG_00529 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
IGGGJKIG_00530 1.7e-220 arcT 2.6.1.1 E Aminotransferase
IGGGJKIG_00531 3.6e-255 E Arginine ornithine antiporter
IGGGJKIG_00532 4.1e-281 yjeM E Amino Acid
IGGGJKIG_00533 3.2e-153 yihY S Belongs to the UPF0761 family
IGGGJKIG_00534 6.6e-34 S Protein of unknown function (DUF2922)
IGGGJKIG_00535 4.9e-31
IGGGJKIG_00536 7.4e-125 recX 2.4.1.337 GT4 S Regulatory protein RecX
IGGGJKIG_00537 3.3e-146 cps1D M Domain of unknown function (DUF4422)
IGGGJKIG_00538 8.3e-176 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IGGGJKIG_00539 5.9e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
IGGGJKIG_00540 0.0 2.7.7.6 M Peptidase family M23
IGGGJKIG_00541 0.0 csd1 3.5.1.28 G domain, Protein
IGGGJKIG_00542 1.7e-145 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
IGGGJKIG_00543 1.1e-63 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IGGGJKIG_00544 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
IGGGJKIG_00545 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IGGGJKIG_00546 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
IGGGJKIG_00547 1.1e-239 hemL 5.4.3.8 H Aminotransferase class-III
IGGGJKIG_00548 6.2e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
IGGGJKIG_00549 3.4e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IGGGJKIG_00550 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IGGGJKIG_00551 6e-58 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
IGGGJKIG_00552 1.3e-239 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
IGGGJKIG_00553 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
IGGGJKIG_00554 3.4e-102 cbiQ P Cobalt transport protein
IGGGJKIG_00555 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IGGGJKIG_00556 1.9e-122 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IGGGJKIG_00557 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IGGGJKIG_00558 8.1e-108 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
IGGGJKIG_00559 3.3e-176 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IGGGJKIG_00560 2.8e-97 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
IGGGJKIG_00561 6.6e-128 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IGGGJKIG_00562 1.1e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
IGGGJKIG_00563 1.4e-128 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IGGGJKIG_00564 4.5e-70 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
IGGGJKIG_00565 3.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IGGGJKIG_00566 1.7e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
IGGGJKIG_00567 9.3e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
IGGGJKIG_00568 1.6e-145 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IGGGJKIG_00569 4.3e-205 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
IGGGJKIG_00570 4.7e-170 cobD 4.1.1.81 E Aminotransferase class I and II
IGGGJKIG_00571 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
IGGGJKIG_00572 1.5e-86
IGGGJKIG_00573 8.9e-67 pgaC GT2 M Glycosyl transferase
IGGGJKIG_00574 2.1e-45 pgaC GT2 M Glycosyl transferase
IGGGJKIG_00575 5.4e-92 pgaC GT2 M Glycosyl transferase
IGGGJKIG_00576 9.7e-141 T EAL domain
IGGGJKIG_00577 1.3e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
IGGGJKIG_00578 1.1e-64 yneR
IGGGJKIG_00579 1.2e-112 GM NAD(P)H-binding
IGGGJKIG_00580 6.1e-88 S membrane
IGGGJKIG_00581 2.1e-74 S membrane
IGGGJKIG_00582 1.3e-90 K Transcriptional regulator C-terminal region
IGGGJKIG_00583 3.2e-118 akr5f 1.1.1.346 S reductase
IGGGJKIG_00584 6.5e-28 akr5f 1.1.1.346 S reductase
IGGGJKIG_00585 4.3e-40 K Transcriptional regulator
IGGGJKIG_00586 2e-169 L Transposase and inactivated derivatives IS30 family
IGGGJKIG_00587 3.3e-78 K Transcriptional regulator
IGGGJKIG_00588 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
IGGGJKIG_00589 2.3e-155 ypuA S Protein of unknown function (DUF1002)
IGGGJKIG_00590 3.6e-66 GM NAD(P)H-binding
IGGGJKIG_00591 3.3e-92 padR K Virulence activator alpha C-term
IGGGJKIG_00592 3.3e-92 padC Q Phenolic acid decarboxylase
IGGGJKIG_00593 2e-152 S Alpha beta hydrolase
IGGGJKIG_00594 9.4e-32 S thiolester hydrolase activity
IGGGJKIG_00595 6.3e-88 lacA S transferase hexapeptide repeat
IGGGJKIG_00596 5.6e-158 K Transcriptional regulator
IGGGJKIG_00597 2.7e-85 C Flavodoxin
IGGGJKIG_00598 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
IGGGJKIG_00599 4e-165 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
IGGGJKIG_00600 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IGGGJKIG_00601 5.3e-83 K Bacterial regulatory proteins, tetR family
IGGGJKIG_00602 4.3e-55 yphJ 4.1.1.44 S decarboxylase
IGGGJKIG_00603 6e-10 P FAD-binding domain
IGGGJKIG_00604 6.4e-21 P nitric oxide dioxygenase activity
IGGGJKIG_00605 4.7e-109 S Peptidase propeptide and YPEB domain
IGGGJKIG_00606 9.9e-239 T GHKL domain
IGGGJKIG_00607 1.1e-39 T Transcriptional regulatory protein, C terminal
IGGGJKIG_00608 6e-108 tdk 2.7.1.21 F thymidine kinase
IGGGJKIG_00609 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IGGGJKIG_00610 4.4e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IGGGJKIG_00611 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IGGGJKIG_00612 3.5e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IGGGJKIG_00613 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IGGGJKIG_00614 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGGGJKIG_00615 9.9e-192 yibE S overlaps another CDS with the same product name
IGGGJKIG_00616 6.3e-129 yibF S overlaps another CDS with the same product name
IGGGJKIG_00617 5e-232 pyrP F Permease
IGGGJKIG_00618 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
IGGGJKIG_00619 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IGGGJKIG_00620 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IGGGJKIG_00621 6.7e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IGGGJKIG_00622 8.9e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IGGGJKIG_00623 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IGGGJKIG_00624 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IGGGJKIG_00625 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IGGGJKIG_00626 1.3e-33 ywzB S Protein of unknown function (DUF1146)
IGGGJKIG_00627 6.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IGGGJKIG_00628 1.9e-178 mbl D Cell shape determining protein MreB Mrl
IGGGJKIG_00629 1e-31 S Protein of unknown function (DUF2969)
IGGGJKIG_00630 4.1e-220 rodA D Belongs to the SEDS family
IGGGJKIG_00631 3.3e-46 gcvH E glycine cleavage
IGGGJKIG_00632 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IGGGJKIG_00633 5.8e-64
IGGGJKIG_00634 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IGGGJKIG_00635 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IGGGJKIG_00636 0.0 dnaK O Heat shock 70 kDa protein
IGGGJKIG_00637 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IGGGJKIG_00638 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IGGGJKIG_00639 4.1e-275 pipD E Dipeptidase
IGGGJKIG_00640 6.8e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IGGGJKIG_00642 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IGGGJKIG_00644 2.8e-57
IGGGJKIG_00645 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
IGGGJKIG_00646 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IGGGJKIG_00647 1.2e-52
IGGGJKIG_00648 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IGGGJKIG_00649 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IGGGJKIG_00650 1.4e-118 yniA G Phosphotransferase enzyme family
IGGGJKIG_00651 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IGGGJKIG_00652 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IGGGJKIG_00653 5.9e-264 glnPH2 P ABC transporter permease
IGGGJKIG_00654 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IGGGJKIG_00655 3.8e-70 yqeY S YqeY-like protein
IGGGJKIG_00656 3.7e-56 ltrA S Bacterial low temperature requirement A protein (LtrA)
IGGGJKIG_00657 8.8e-44 ltrA S Bacterial low temperature requirement A protein (LtrA)
IGGGJKIG_00658 1.6e-79 uspA T universal stress protein
IGGGJKIG_00659 1.5e-80 K AsnC family
IGGGJKIG_00660 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IGGGJKIG_00661 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
IGGGJKIG_00662 2e-180 galR K Transcriptional regulator
IGGGJKIG_00663 7.6e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IGGGJKIG_00664 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IGGGJKIG_00665 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
IGGGJKIG_00666 4.4e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
IGGGJKIG_00667 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
IGGGJKIG_00668 9.1e-36
IGGGJKIG_00669 5.9e-52
IGGGJKIG_00670 2.3e-204
IGGGJKIG_00671 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IGGGJKIG_00672 8.9e-136 pnuC H nicotinamide mononucleotide transporter
IGGGJKIG_00673 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
IGGGJKIG_00674 3.2e-124 K response regulator
IGGGJKIG_00675 1.3e-179 T PhoQ Sensor
IGGGJKIG_00676 1.3e-134 macB2 V ABC transporter, ATP-binding protein
IGGGJKIG_00677 0.0 ysaB V FtsX-like permease family
IGGGJKIG_00678 8.9e-173 L PFAM Integrase catalytic region
IGGGJKIG_00679 4.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IGGGJKIG_00680 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IGGGJKIG_00681 1.6e-21 K helix_turn_helix, mercury resistance
IGGGJKIG_00682 2e-161 EG EamA-like transporter family
IGGGJKIG_00683 3e-125 dnaD L DnaD domain protein
IGGGJKIG_00684 2.9e-85 ypmB S Protein conserved in bacteria
IGGGJKIG_00685 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IGGGJKIG_00686 5.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IGGGJKIG_00687 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IGGGJKIG_00688 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IGGGJKIG_00689 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IGGGJKIG_00690 3.8e-87 S Protein of unknown function (DUF1440)
IGGGJKIG_00691 0.0 rafA 3.2.1.22 G alpha-galactosidase
IGGGJKIG_00692 4.2e-189 galR K Periplasmic binding protein-like domain
IGGGJKIG_00693 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IGGGJKIG_00694 1.2e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IGGGJKIG_00695 2.2e-123 lrgB M LrgB-like family
IGGGJKIG_00696 1.9e-66 lrgA S LrgA family
IGGGJKIG_00697 2.4e-130 lytT K response regulator receiver
IGGGJKIG_00698 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
IGGGJKIG_00699 2e-147 f42a O Band 7 protein
IGGGJKIG_00700 1.7e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IGGGJKIG_00701 2.2e-156 yitU 3.1.3.104 S hydrolase
IGGGJKIG_00702 9.2e-39 S Cytochrome B5
IGGGJKIG_00703 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IGGGJKIG_00704 4e-56 K transcriptional regulator PadR family
IGGGJKIG_00705 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
IGGGJKIG_00706 6.4e-126 S Putative adhesin
IGGGJKIG_00707 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IGGGJKIG_00708 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGGGJKIG_00709 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IGGGJKIG_00710 3.4e-35 nrdH O Glutaredoxin
IGGGJKIG_00711 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IGGGJKIG_00712 3.8e-297 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGGGJKIG_00713 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IGGGJKIG_00714 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IGGGJKIG_00715 9.7e-39 S Protein of unknown function (DUF2508)
IGGGJKIG_00716 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IGGGJKIG_00717 7.6e-52 yaaQ S Cyclic-di-AMP receptor
IGGGJKIG_00718 8.2e-185 holB 2.7.7.7 L DNA polymerase III
IGGGJKIG_00719 5.9e-58 yabA L Involved in initiation control of chromosome replication
IGGGJKIG_00720 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IGGGJKIG_00721 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
IGGGJKIG_00722 3.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IGGGJKIG_00723 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IGGGJKIG_00724 5.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IGGGJKIG_00725 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IGGGJKIG_00726 7.8e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGGGJKIG_00727 1.6e-197 EGP Major facilitator Superfamily
IGGGJKIG_00728 2.1e-88 ymdB S Macro domain protein
IGGGJKIG_00729 8.4e-111 K Helix-turn-helix domain
IGGGJKIG_00730 0.0 pepO 3.4.24.71 O Peptidase family M13
IGGGJKIG_00731 5.1e-47
IGGGJKIG_00732 4.2e-242 S Putative metallopeptidase domain
IGGGJKIG_00733 3e-204 3.1.3.1 S associated with various cellular activities
IGGGJKIG_00734 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IGGGJKIG_00735 1.6e-64 yeaO S Protein of unknown function, DUF488
IGGGJKIG_00737 5.4e-116 yrkL S Flavodoxin-like fold
IGGGJKIG_00738 9.5e-55
IGGGJKIG_00739 2e-15 S Domain of unknown function (DUF4767)
IGGGJKIG_00740 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IGGGJKIG_00741 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IGGGJKIG_00742 6.9e-49
IGGGJKIG_00743 4.9e-204 nrnB S DHHA1 domain
IGGGJKIG_00744 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
IGGGJKIG_00745 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
IGGGJKIG_00746 3.4e-106 NU mannosyl-glycoprotein
IGGGJKIG_00747 2.3e-142 S Putative ABC-transporter type IV
IGGGJKIG_00748 7.8e-272 S ABC transporter, ATP-binding protein
IGGGJKIG_00749 8.2e-48
IGGGJKIG_00750 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IGGGJKIG_00751 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IGGGJKIG_00752 1.6e-105 ypsA S Belongs to the UPF0398 family
IGGGJKIG_00753 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IGGGJKIG_00754 1.1e-83 F Belongs to the NrdI family
IGGGJKIG_00755 5.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IGGGJKIG_00756 3.4e-70 rnhA 3.1.26.4 L Ribonuclease HI
IGGGJKIG_00757 1.5e-65 esbA S Family of unknown function (DUF5322)
IGGGJKIG_00758 1.3e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IGGGJKIG_00759 2.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IGGGJKIG_00760 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
IGGGJKIG_00761 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IGGGJKIG_00762 0.0 FbpA K Fibronectin-binding protein
IGGGJKIG_00763 1.9e-161 degV S EDD domain protein, DegV family
IGGGJKIG_00764 3.8e-93
IGGGJKIG_00765 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IGGGJKIG_00766 1.1e-158 gspA M family 8
IGGGJKIG_00767 1.2e-160 S Alpha beta hydrolase
IGGGJKIG_00768 1.5e-94 K Acetyltransferase (GNAT) domain
IGGGJKIG_00769 1.5e-239 XK27_08635 S UPF0210 protein
IGGGJKIG_00770 2.1e-39 gcvR T Belongs to the UPF0237 family
IGGGJKIG_00771 1.7e-170 1.1.1.346 C Aldo keto reductase
IGGGJKIG_00772 1.4e-47 yktA S Belongs to the UPF0223 family
IGGGJKIG_00773 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IGGGJKIG_00774 0.0 typA T GTP-binding protein TypA
IGGGJKIG_00775 2e-222 ftsW D Belongs to the SEDS family
IGGGJKIG_00776 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IGGGJKIG_00777 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IGGGJKIG_00778 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IGGGJKIG_00779 3.3e-197 ylbL T Belongs to the peptidase S16 family
IGGGJKIG_00780 2.6e-80 comEA L Competence protein ComEA
IGGGJKIG_00781 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
IGGGJKIG_00782 0.0 comEC S Competence protein ComEC
IGGGJKIG_00783 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
IGGGJKIG_00784 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
IGGGJKIG_00785 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IGGGJKIG_00786 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IGGGJKIG_00787 1.3e-162 S Tetratricopeptide repeat
IGGGJKIG_00788 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IGGGJKIG_00789 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IGGGJKIG_00790 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IGGGJKIG_00791 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
IGGGJKIG_00792 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IGGGJKIG_00793 1.3e-08
IGGGJKIG_00794 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IGGGJKIG_00795 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IGGGJKIG_00796 1.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IGGGJKIG_00797 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IGGGJKIG_00798 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IGGGJKIG_00799 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IGGGJKIG_00800 2.1e-87
IGGGJKIG_00801 4.1e-134 L Belongs to the 'phage' integrase family
IGGGJKIG_00802 3.6e-35 S Domain of unknown function (DUF5067)
IGGGJKIG_00803 3.8e-10 K sequence-specific DNA binding
IGGGJKIG_00804 1.6e-14 S Helix-turn-helix domain
IGGGJKIG_00805 1.8e-41 S Phage regulatory protein Rha (Phage_pRha)
IGGGJKIG_00808 9.3e-08
IGGGJKIG_00811 4.5e-56 S DNA primase
IGGGJKIG_00812 1.4e-14
IGGGJKIG_00818 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IGGGJKIG_00819 2.4e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IGGGJKIG_00820 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IGGGJKIG_00821 1.3e-35 ynzC S UPF0291 protein
IGGGJKIG_00822 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
IGGGJKIG_00823 4.6e-117 plsC 2.3.1.51 I Acyltransferase
IGGGJKIG_00824 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
IGGGJKIG_00825 5.4e-49 yazA L GIY-YIG catalytic domain protein
IGGGJKIG_00826 4.4e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGGGJKIG_00827 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
IGGGJKIG_00828 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IGGGJKIG_00829 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IGGGJKIG_00830 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IGGGJKIG_00831 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IGGGJKIG_00832 1.7e-137 cdsA 2.7.7.41 I Belongs to the CDS family
IGGGJKIG_00833 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IGGGJKIG_00834 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IGGGJKIG_00835 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IGGGJKIG_00836 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
IGGGJKIG_00837 1e-215 nusA K Participates in both transcription termination and antitermination
IGGGJKIG_00838 1e-44 ylxR K Protein of unknown function (DUF448)
IGGGJKIG_00839 4.5e-49 ylxQ J ribosomal protein
IGGGJKIG_00840 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IGGGJKIG_00841 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IGGGJKIG_00842 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IGGGJKIG_00843 1.7e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IGGGJKIG_00844 1.3e-123 K LysR substrate binding domain protein
IGGGJKIG_00845 3.2e-83 C Flavodoxin
IGGGJKIG_00846 5.6e-79 yphH S Cupin domain
IGGGJKIG_00847 1e-73 yeaL S UPF0756 membrane protein
IGGGJKIG_00848 1.3e-244 EGP Major facilitator Superfamily
IGGGJKIG_00849 5e-75 copY K Copper transport repressor CopY TcrY
IGGGJKIG_00850 2.5e-245 yhdP S Transporter associated domain
IGGGJKIG_00851 0.0 ubiB S ABC1 family
IGGGJKIG_00852 9.6e-144 S DUF218 domain
IGGGJKIG_00853 3.2e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IGGGJKIG_00854 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IGGGJKIG_00855 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IGGGJKIG_00856 0.0 uvrA3 L excinuclease ABC, A subunit
IGGGJKIG_00857 4.6e-123 S SNARE associated Golgi protein
IGGGJKIG_00858 1.9e-228 N Uncharacterized conserved protein (DUF2075)
IGGGJKIG_00859 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IGGGJKIG_00861 1e-254 yifK E Amino acid permease
IGGGJKIG_00862 5.5e-158 endA V DNA/RNA non-specific endonuclease
IGGGJKIG_00863 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGGGJKIG_00864 6.2e-76 K Transcriptional regulator, TetR family
IGGGJKIG_00865 4.3e-13 K Transcriptional regulator, TetR family
IGGGJKIG_00867 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IGGGJKIG_00868 3e-86
IGGGJKIG_00869 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IGGGJKIG_00870 9.6e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IGGGJKIG_00871 4.2e-261 nox C NADH oxidase
IGGGJKIG_00872 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
IGGGJKIG_00873 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
IGGGJKIG_00874 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
IGGGJKIG_00875 3.8e-167 yvgN C Aldo keto reductase
IGGGJKIG_00876 6.6e-136 puuD S peptidase C26
IGGGJKIG_00877 8.1e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IGGGJKIG_00878 2.5e-209 yfeO P Voltage gated chloride channel
IGGGJKIG_00879 5.3e-226 sptS 2.7.13.3 T Histidine kinase
IGGGJKIG_00880 3.3e-118 K response regulator
IGGGJKIG_00881 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
IGGGJKIG_00882 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IGGGJKIG_00883 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IGGGJKIG_00884 1.1e-256 malT G Major Facilitator
IGGGJKIG_00885 3.6e-83 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
IGGGJKIG_00886 8.5e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IGGGJKIG_00887 1.5e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IGGGJKIG_00888 4.7e-102 T Ion transport 2 domain protein
IGGGJKIG_00889 0.0 S Bacterial membrane protein YfhO
IGGGJKIG_00890 5e-202 G Transporter, major facilitator family protein
IGGGJKIG_00891 1.3e-107 yvrI K sigma factor activity
IGGGJKIG_00892 3.5e-64 ydiI Q Thioesterase superfamily
IGGGJKIG_00893 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IGGGJKIG_00894 4.4e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IGGGJKIG_00895 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IGGGJKIG_00896 4.2e-32 feoA P FeoA domain
IGGGJKIG_00897 6.5e-145 sufC O FeS assembly ATPase SufC
IGGGJKIG_00898 7.3e-239 sufD O FeS assembly protein SufD
IGGGJKIG_00899 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IGGGJKIG_00900 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
IGGGJKIG_00901 1.6e-271 sufB O assembly protein SufB
IGGGJKIG_00902 3.6e-57 yitW S Iron-sulfur cluster assembly protein
IGGGJKIG_00903 3.2e-161 hipB K Helix-turn-helix
IGGGJKIG_00904 7.8e-112 nreC K PFAM regulatory protein LuxR
IGGGJKIG_00905 5.3e-165 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGGGJKIG_00906 6.1e-216 patA 2.6.1.1 E Aminotransferase
IGGGJKIG_00907 7.8e-32
IGGGJKIG_00908 0.0 clpL O associated with various cellular activities
IGGGJKIG_00910 6.2e-34 wecD3 K PFAM GCN5-related N-acetyltransferase
IGGGJKIG_00911 1.7e-60 wecD3 K PFAM GCN5-related N-acetyltransferase
IGGGJKIG_00912 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IGGGJKIG_00913 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IGGGJKIG_00914 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IGGGJKIG_00915 1.6e-171 malR K Transcriptional regulator, LacI family
IGGGJKIG_00916 1.4e-212 phbA 2.3.1.9 I Belongs to the thiolase family
IGGGJKIG_00917 7.1e-240 E amino acid
IGGGJKIG_00918 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IGGGJKIG_00920 1.5e-211 yxjG_1 E methionine synthase, vitamin-B12 independent
IGGGJKIG_00921 7.8e-41 S Cytochrome B5
IGGGJKIG_00922 5.4e-09 S Cytochrome B5
IGGGJKIG_00923 1.7e-33 S Cytochrome B5
IGGGJKIG_00924 1.7e-70 elaA S Gnat family
IGGGJKIG_00925 3e-119 GM NmrA-like family
IGGGJKIG_00926 2.5e-52 hxlR K Transcriptional regulator, HxlR family
IGGGJKIG_00927 3.7e-108 XK27_02070 S Nitroreductase family
IGGGJKIG_00928 1.6e-43 K Transcriptional regulator, HxlR family
IGGGJKIG_00929 5.5e-26 K Transcriptional regulator, HxlR family
IGGGJKIG_00930 1.8e-229
IGGGJKIG_00931 6.5e-210 EGP Major facilitator Superfamily
IGGGJKIG_00932 9.8e-255 pepC 3.4.22.40 E aminopeptidase
IGGGJKIG_00933 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
IGGGJKIG_00934 0.0 pepN 3.4.11.2 E aminopeptidase
IGGGJKIG_00935 2e-92 folT S ECF transporter, substrate-specific component
IGGGJKIG_00936 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
IGGGJKIG_00937 3.9e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IGGGJKIG_00938 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
IGGGJKIG_00939 1.7e-202 2.7.7.65 T GGDEF domain
IGGGJKIG_00940 1.2e-160 EG EamA-like transporter family
IGGGJKIG_00941 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IGGGJKIG_00942 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IGGGJKIG_00943 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IGGGJKIG_00944 0.0 copA 3.6.3.54 P P-type ATPase
IGGGJKIG_00945 4.5e-85
IGGGJKIG_00947 5.2e-56
IGGGJKIG_00949 1e-73 yjcE P Sodium proton antiporter
IGGGJKIG_00950 3.2e-159 yjcE P Sodium proton antiporter
IGGGJKIG_00952 5.9e-91
IGGGJKIG_00953 0.0 M domain protein
IGGGJKIG_00954 1.1e-19
IGGGJKIG_00955 3.9e-187 ampC V Beta-lactamase
IGGGJKIG_00956 4.1e-239 arcA 3.5.3.6 E Arginine
IGGGJKIG_00957 4.7e-79 argR K Regulates arginine biosynthesis genes
IGGGJKIG_00958 2e-261 E Arginine ornithine antiporter
IGGGJKIG_00959 2.7e-223 arcD U Amino acid permease
IGGGJKIG_00960 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
IGGGJKIG_00961 3.4e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
IGGGJKIG_00962 7.7e-130 ponA V Beta-lactamase enzyme family
IGGGJKIG_00963 4.9e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
IGGGJKIG_00964 6.3e-216 uhpT EGP Major facilitator Superfamily
IGGGJKIG_00965 1.6e-257 ytjP 3.5.1.18 E Dipeptidase
IGGGJKIG_00966 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
IGGGJKIG_00967 4.8e-179 yfeX P Peroxidase
IGGGJKIG_00968 1.4e-169 lsa S ABC transporter
IGGGJKIG_00969 4.6e-134 I alpha/beta hydrolase fold
IGGGJKIG_00970 8e-180 MA20_14895 S Conserved hypothetical protein 698
IGGGJKIG_00971 3.5e-67 S NADPH-dependent FMN reductase
IGGGJKIG_00972 8.7e-09 S NADPH-dependent FMN reductase
IGGGJKIG_00973 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IGGGJKIG_00974 6.2e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IGGGJKIG_00975 1e-232 mntH P H( )-stimulated, divalent metal cation uptake system
IGGGJKIG_00976 3.2e-79 Q Methyltransferase
IGGGJKIG_00977 5.3e-116 ktrA P domain protein
IGGGJKIG_00978 6.5e-238 ktrB P Potassium uptake protein
IGGGJKIG_00979 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
IGGGJKIG_00980 7.6e-126 narI 1.7.5.1 C Nitrate reductase
IGGGJKIG_00981 6.9e-96 narJ C nitrate reductase molybdenum cofactor assembly chaperone
IGGGJKIG_00982 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
IGGGJKIG_00983 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IGGGJKIG_00984 3.3e-186 moeB 2.7.7.73, 2.7.7.80 H ThiF family
IGGGJKIG_00985 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IGGGJKIG_00986 8.5e-229 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
IGGGJKIG_00987 5.1e-84 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IGGGJKIG_00988 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IGGGJKIG_00989 3e-44
IGGGJKIG_00990 1.8e-190 comP 2.7.13.3 F Sensor histidine kinase
IGGGJKIG_00991 2.3e-116 nreC K PFAM regulatory protein LuxR
IGGGJKIG_00992 4.6e-18
IGGGJKIG_00993 3.6e-182
IGGGJKIG_00994 2.9e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
IGGGJKIG_00995 3.9e-218 narK P Transporter, major facilitator family protein
IGGGJKIG_00996 4.9e-35 moaD 2.8.1.12 H ThiS family
IGGGJKIG_00997 3.7e-64 moaE 2.8.1.12 H MoaE protein
IGGGJKIG_00998 3.3e-77 S Flavodoxin
IGGGJKIG_00999 1.8e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IGGGJKIG_01000 1.4e-139 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
IGGGJKIG_01001 7.7e-175 fecB P Periplasmic binding protein
IGGGJKIG_01002 6.1e-54 trxA O Belongs to the thioredoxin family
IGGGJKIG_01003 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IGGGJKIG_01004 1.7e-85 cvpA S Colicin V production protein
IGGGJKIG_01005 6.1e-48 yrzB S Belongs to the UPF0473 family
IGGGJKIG_01006 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IGGGJKIG_01007 4.1e-43 yrzL S Belongs to the UPF0297 family
IGGGJKIG_01008 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IGGGJKIG_01009 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IGGGJKIG_01010 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IGGGJKIG_01011 2.8e-31 yajC U Preprotein translocase
IGGGJKIG_01012 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IGGGJKIG_01013 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IGGGJKIG_01014 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IGGGJKIG_01015 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IGGGJKIG_01016 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IGGGJKIG_01017 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
IGGGJKIG_01018 6.2e-131 S Hydrolases of the alpha beta superfamily
IGGGJKIG_01019 1.3e-16 S Hydrolases of the alpha beta superfamily
IGGGJKIG_01020 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
IGGGJKIG_01021 3.4e-77 ctsR K Belongs to the CtsR family
IGGGJKIG_01022 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IGGGJKIG_01023 1e-110 K Bacterial regulatory proteins, tetR family
IGGGJKIG_01024 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGGGJKIG_01025 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGGGJKIG_01026 2.2e-202 ykiI
IGGGJKIG_01027 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IGGGJKIG_01028 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IGGGJKIG_01029 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IGGGJKIG_01030 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IGGGJKIG_01031 5.9e-48 L PFAM transposase IS200-family protein
IGGGJKIG_01032 8.8e-71 yneR S Belongs to the HesB IscA family
IGGGJKIG_01033 0.0 S membrane
IGGGJKIG_01034 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IGGGJKIG_01035 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IGGGJKIG_01036 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IGGGJKIG_01037 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
IGGGJKIG_01038 1.4e-26 gluP 3.4.21.105 S Peptidase, S54 family
IGGGJKIG_01039 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
IGGGJKIG_01040 5.6e-183 glk 2.7.1.2 G Glucokinase
IGGGJKIG_01041 3.4e-67 yqhL P Rhodanese-like protein
IGGGJKIG_01042 1.3e-21 S Protein of unknown function (DUF3042)
IGGGJKIG_01043 4.4e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IGGGJKIG_01044 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
IGGGJKIG_01045 3.8e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IGGGJKIG_01046 3.8e-19 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IGGGJKIG_01047 1.9e-178 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IGGGJKIG_01048 3.9e-12
IGGGJKIG_01049 2.2e-154 P Belongs to the nlpA lipoprotein family
IGGGJKIG_01050 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IGGGJKIG_01051 3.7e-51 S Iron-sulfur cluster assembly protein
IGGGJKIG_01052 1e-151
IGGGJKIG_01053 6.6e-174
IGGGJKIG_01054 2.5e-89 dut S Protein conserved in bacteria
IGGGJKIG_01058 8.3e-111 K Transcriptional regulator
IGGGJKIG_01059 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
IGGGJKIG_01060 1.6e-54 ysxB J Cysteine protease Prp
IGGGJKIG_01061 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IGGGJKIG_01062 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IGGGJKIG_01063 1.1e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IGGGJKIG_01064 2.9e-114 J 2'-5' RNA ligase superfamily
IGGGJKIG_01065 2.2e-70 yqhY S Asp23 family, cell envelope-related function
IGGGJKIG_01066 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IGGGJKIG_01067 2.1e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IGGGJKIG_01068 2e-223 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IGGGJKIG_01069 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IGGGJKIG_01070 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IGGGJKIG_01071 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IGGGJKIG_01072 3.3e-77 argR K Regulates arginine biosynthesis genes
IGGGJKIG_01073 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
IGGGJKIG_01074 1.7e-54
IGGGJKIG_01075 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IGGGJKIG_01076 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IGGGJKIG_01077 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IGGGJKIG_01078 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IGGGJKIG_01079 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IGGGJKIG_01080 9.6e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IGGGJKIG_01081 2.9e-131 stp 3.1.3.16 T phosphatase
IGGGJKIG_01082 0.0 KLT serine threonine protein kinase
IGGGJKIG_01083 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IGGGJKIG_01084 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IGGGJKIG_01085 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
IGGGJKIG_01086 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IGGGJKIG_01087 4.7e-58 asp S Asp23 family, cell envelope-related function
IGGGJKIG_01088 7.1e-311 yloV S DAK2 domain fusion protein YloV
IGGGJKIG_01089 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IGGGJKIG_01090 6.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IGGGJKIG_01091 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IGGGJKIG_01092 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IGGGJKIG_01093 0.0 smc D Required for chromosome condensation and partitioning
IGGGJKIG_01094 2.7e-179 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IGGGJKIG_01095 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IGGGJKIG_01096 2.3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IGGGJKIG_01097 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IGGGJKIG_01098 1e-38 ylqC S Belongs to the UPF0109 family
IGGGJKIG_01099 9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IGGGJKIG_01100 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IGGGJKIG_01101 9.9e-261 yfnA E amino acid
IGGGJKIG_01102 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IGGGJKIG_01103 2.9e-34
IGGGJKIG_01104 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
IGGGJKIG_01105 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
IGGGJKIG_01106 3.3e-83
IGGGJKIG_01107 7.3e-90 L Transposase
IGGGJKIG_01108 2.4e-235 pbuG S permease
IGGGJKIG_01109 1.1e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IGGGJKIG_01110 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IGGGJKIG_01111 2.5e-135 S Belongs to the UPF0246 family
IGGGJKIG_01112 2.5e-138 S Membrane
IGGGJKIG_01113 8.1e-75 4.4.1.5 E Glyoxalase
IGGGJKIG_01114 1.5e-21
IGGGJKIG_01115 7.1e-86 yueI S Protein of unknown function (DUF1694)
IGGGJKIG_01116 1.7e-235 rarA L recombination factor protein RarA
IGGGJKIG_01117 4.4e-46
IGGGJKIG_01118 4.3e-83 usp6 T universal stress protein
IGGGJKIG_01119 2.8e-207 araR K Transcriptional regulator
IGGGJKIG_01120 7.1e-158 ytbE 1.1.1.346 S Aldo keto reductase
IGGGJKIG_01121 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
IGGGJKIG_01122 1.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IGGGJKIG_01123 7e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IGGGJKIG_01124 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
IGGGJKIG_01125 9.8e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IGGGJKIG_01126 1.4e-20
IGGGJKIG_01127 0.0 L Helicase C-terminal domain protein
IGGGJKIG_01128 9.5e-47 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
IGGGJKIG_01129 2.1e-260 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IGGGJKIG_01130 5.1e-187 yegS 2.7.1.107 G Lipid kinase
IGGGJKIG_01131 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IGGGJKIG_01132 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IGGGJKIG_01133 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IGGGJKIG_01134 2.1e-202 camS S sex pheromone
IGGGJKIG_01135 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IGGGJKIG_01136 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IGGGJKIG_01137 4.3e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IGGGJKIG_01138 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IGGGJKIG_01139 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
IGGGJKIG_01140 2e-138 IQ reductase
IGGGJKIG_01141 7.4e-68 rmaI K Transcriptional regulator
IGGGJKIG_01142 5.4e-235 EGP Major facilitator Superfamily
IGGGJKIG_01143 2.9e-111 yvyE 3.4.13.9 S YigZ family
IGGGJKIG_01144 1.4e-256 comFA L Helicase C-terminal domain protein
IGGGJKIG_01145 1.3e-114 comFC S Competence protein
IGGGJKIG_01146 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IGGGJKIG_01147 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IGGGJKIG_01148 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IGGGJKIG_01149 3.1e-32 KT PspC domain protein
IGGGJKIG_01150 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IGGGJKIG_01151 7.8e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IGGGJKIG_01152 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IGGGJKIG_01153 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IGGGJKIG_01154 7.4e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IGGGJKIG_01155 3.9e-136 yrjD S LUD domain
IGGGJKIG_01156 7.5e-288 lutB C 4Fe-4S dicluster domain
IGGGJKIG_01157 3.5e-163 lutA C Cysteine-rich domain
IGGGJKIG_01158 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IGGGJKIG_01159 1.8e-147 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IGGGJKIG_01160 9.2e-40
IGGGJKIG_01161 0.0 ydaO E amino acid
IGGGJKIG_01162 4.3e-305 ybeC E amino acid
IGGGJKIG_01163 8.2e-82 S YbaK proline--tRNA ligase associated domain protein
IGGGJKIG_01164 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IGGGJKIG_01165 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IGGGJKIG_01167 3.1e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IGGGJKIG_01168 0.0 uup S ABC transporter, ATP-binding protein
IGGGJKIG_01169 4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IGGGJKIG_01170 4.2e-225 mtnE 2.6.1.83 E Aminotransferase
IGGGJKIG_01171 6.6e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IGGGJKIG_01172 1.2e-135 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IGGGJKIG_01173 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IGGGJKIG_01174 4.7e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IGGGJKIG_01175 2.5e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IGGGJKIG_01176 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IGGGJKIG_01177 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IGGGJKIG_01179 1.5e-48
IGGGJKIG_01180 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IGGGJKIG_01181 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IGGGJKIG_01182 2.7e-126 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IGGGJKIG_01183 3.9e-60 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IGGGJKIG_01184 3.4e-244 M Glycosyl transferase family group 2
IGGGJKIG_01186 1.3e-226 aadAT EK Aminotransferase, class I
IGGGJKIG_01187 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IGGGJKIG_01188 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IGGGJKIG_01189 1.7e-96 nusG K Participates in transcription elongation, termination and antitermination
IGGGJKIG_01190 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IGGGJKIG_01191 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IGGGJKIG_01192 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGGGJKIG_01193 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IGGGJKIG_01194 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IGGGJKIG_01195 8.7e-182 L COG2826 Transposase and inactivated derivatives, IS30 family
IGGGJKIG_01196 3.8e-76 azlC E azaleucine resistance protein AzlC
IGGGJKIG_01197 7.1e-50 azlD E Branched-chain amino acid transport
IGGGJKIG_01198 6.1e-117 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IGGGJKIG_01200 2.7e-70 S GyrI-like small molecule binding domain
IGGGJKIG_01201 6.4e-39 S GyrI-like small molecule binding domain
IGGGJKIG_01202 5e-122 yhiD S MgtC family
IGGGJKIG_01203 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IGGGJKIG_01204 5.9e-191 V Beta-lactamase
IGGGJKIG_01205 2.2e-271 nylA 3.5.1.4 J Belongs to the amidase family
IGGGJKIG_01206 2.2e-44
IGGGJKIG_01207 9.5e-54 yhaI S Protein of unknown function (DUF805)
IGGGJKIG_01208 1.1e-139 IQ reductase
IGGGJKIG_01209 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IGGGJKIG_01210 2e-289 hsdM 2.1.1.72 V type I restriction-modification system
IGGGJKIG_01211 2.7e-110 hsdS-1 3.1.21.3 L Type I restriction modification DNA specificity domain
IGGGJKIG_01212 5.8e-34 S RelE-like toxin of type II toxin-antitoxin system HigB
IGGGJKIG_01213 1.9e-46 L Transposase
IGGGJKIG_01214 3.4e-171 L Integrase core domain
IGGGJKIG_01215 2.4e-170 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IGGGJKIG_01216 1e-88 mrr L restriction endonuclease
IGGGJKIG_01217 4.5e-150 L restriction endonuclease
IGGGJKIG_01218 1.1e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IGGGJKIG_01219 3.4e-177 L Belongs to the 'phage' integrase family
IGGGJKIG_01220 8.6e-40 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IGGGJKIG_01221 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IGGGJKIG_01222 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IGGGJKIG_01223 2.6e-149 purR 2.4.2.7 F pur operon repressor
IGGGJKIG_01224 1.4e-118 znuB U ABC 3 transport family
IGGGJKIG_01225 5.5e-121 fhuC P ABC transporter
IGGGJKIG_01226 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
IGGGJKIG_01227 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IGGGJKIG_01228 6.8e-37 veg S Biofilm formation stimulator VEG
IGGGJKIG_01229 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IGGGJKIG_01230 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IGGGJKIG_01231 1.9e-155 tatD L hydrolase, TatD family
IGGGJKIG_01232 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IGGGJKIG_01233 3.6e-162 yunF F Protein of unknown function DUF72
IGGGJKIG_01235 1e-130 cobB K SIR2 family
IGGGJKIG_01236 1.6e-177
IGGGJKIG_01237 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IGGGJKIG_01238 2.7e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IGGGJKIG_01239 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IGGGJKIG_01240 0.0 cadA P P-type ATPase
IGGGJKIG_01241 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
IGGGJKIG_01243 2.4e-153 1.6.5.2 GM NAD(P)H-binding
IGGGJKIG_01244 2.6e-74 K Transcriptional regulator
IGGGJKIG_01245 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
IGGGJKIG_01246 8.2e-109 proWZ P ABC transporter permease
IGGGJKIG_01247 1e-139 proV E ABC transporter, ATP-binding protein
IGGGJKIG_01248 4.5e-104 proW P ABC transporter, permease protein
IGGGJKIG_01249 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IGGGJKIG_01250 7.8e-252 clcA P chloride
IGGGJKIG_01251 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IGGGJKIG_01252 3.1e-103 metI P ABC transporter permease
IGGGJKIG_01253 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IGGGJKIG_01254 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
IGGGJKIG_01255 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IGGGJKIG_01256 3.3e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IGGGJKIG_01257 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
IGGGJKIG_01258 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IGGGJKIG_01259 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IGGGJKIG_01260 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IGGGJKIG_01261 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IGGGJKIG_01262 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IGGGJKIG_01263 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IGGGJKIG_01264 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
IGGGJKIG_01265 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IGGGJKIG_01266 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IGGGJKIG_01267 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IGGGJKIG_01268 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IGGGJKIG_01269 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IGGGJKIG_01270 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IGGGJKIG_01271 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IGGGJKIG_01272 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IGGGJKIG_01273 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IGGGJKIG_01274 2.9e-24 rpmD J Ribosomal protein L30
IGGGJKIG_01275 8.9e-64 rplO J Binds to the 23S rRNA
IGGGJKIG_01276 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IGGGJKIG_01277 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IGGGJKIG_01278 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IGGGJKIG_01279 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IGGGJKIG_01280 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IGGGJKIG_01281 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IGGGJKIG_01282 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IGGGJKIG_01283 1.1e-62 rplQ J Ribosomal protein L17
IGGGJKIG_01284 1.2e-25 czrA K Transcriptional regulator, ArsR family
IGGGJKIG_01285 4.6e-38
IGGGJKIG_01286 0.0 yhcA V ABC transporter, ATP-binding protein
IGGGJKIG_01287 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IGGGJKIG_01288 3.7e-177 hrtB V ABC transporter permease
IGGGJKIG_01289 2.6e-86 ygfC K transcriptional regulator (TetR family)
IGGGJKIG_01290 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
IGGGJKIG_01291 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
IGGGJKIG_01292 3e-34
IGGGJKIG_01293 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IGGGJKIG_01295 3.1e-226 yxiO S Vacuole effluxer Atg22 like
IGGGJKIG_01296 2.8e-215 npp S type I phosphodiesterase nucleotide pyrophosphatase
IGGGJKIG_01297 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
IGGGJKIG_01298 1.7e-84 F NUDIX domain
IGGGJKIG_01299 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IGGGJKIG_01300 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IGGGJKIG_01301 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IGGGJKIG_01302 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
IGGGJKIG_01303 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IGGGJKIG_01304 2.1e-160 dprA LU DNA protecting protein DprA
IGGGJKIG_01305 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IGGGJKIG_01306 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IGGGJKIG_01307 4.4e-35 yozE S Belongs to the UPF0346 family
IGGGJKIG_01308 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IGGGJKIG_01309 9.5e-172 ypmR E lipolytic protein G-D-S-L family
IGGGJKIG_01310 1.7e-151 DegV S EDD domain protein, DegV family
IGGGJKIG_01311 5.3e-113 hlyIII S protein, hemolysin III
IGGGJKIG_01312 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IGGGJKIG_01313 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IGGGJKIG_01314 0.0 yfmR S ABC transporter, ATP-binding protein
IGGGJKIG_01315 2.1e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IGGGJKIG_01316 1.5e-236 S Tetratricopeptide repeat protein
IGGGJKIG_01317 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IGGGJKIG_01318 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IGGGJKIG_01319 2.5e-204 rpsA 1.17.7.4 J Ribosomal protein S1
IGGGJKIG_01320 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IGGGJKIG_01321 8.8e-26 M Lysin motif
IGGGJKIG_01322 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IGGGJKIG_01323 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
IGGGJKIG_01324 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IGGGJKIG_01325 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IGGGJKIG_01326 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IGGGJKIG_01327 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IGGGJKIG_01328 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IGGGJKIG_01329 5.9e-163 xerD D recombinase XerD
IGGGJKIG_01330 2.3e-167 cvfB S S1 domain
IGGGJKIG_01331 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IGGGJKIG_01332 0.0 dnaE 2.7.7.7 L DNA polymerase
IGGGJKIG_01333 3e-30 S Protein of unknown function (DUF2929)
IGGGJKIG_01334 1.1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IGGGJKIG_01335 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IGGGJKIG_01336 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
IGGGJKIG_01337 1.2e-219 patA 2.6.1.1 E Aminotransferase
IGGGJKIG_01338 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IGGGJKIG_01339 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IGGGJKIG_01340 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IGGGJKIG_01341 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IGGGJKIG_01342 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
IGGGJKIG_01343 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IGGGJKIG_01344 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IGGGJKIG_01345 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IGGGJKIG_01346 8.4e-182 phoH T phosphate starvation-inducible protein PhoH
IGGGJKIG_01347 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IGGGJKIG_01348 1.1e-90 bioY S BioY family
IGGGJKIG_01349 3.9e-262 argH 4.3.2.1 E argininosuccinate lyase
IGGGJKIG_01350 1.2e-134 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IGGGJKIG_01351 5.5e-40 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IGGGJKIG_01352 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IGGGJKIG_01357 9e-41 L Psort location Cytoplasmic, score 8.96
IGGGJKIG_01358 1.1e-38 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IGGGJKIG_01359 3e-16 L transposase and inactivated derivatives, IS30 family
IGGGJKIG_01360 5e-128 yocS S Transporter
IGGGJKIG_01361 1e-27 XK27_02560 S Pfam:DUF59
IGGGJKIG_01362 7.6e-260 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IGGGJKIG_01363 2.1e-106 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IGGGJKIG_01364 0.0 ilvD 4.2.1.9 EG Belongs to the IlvD Edd family
IGGGJKIG_01365 1.2e-39 S Iron-sulfur cluster assembly protein
IGGGJKIG_01366 3e-155 yocS S SBF-like CPA transporter family (DUF4137)
IGGGJKIG_01367 2.8e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
IGGGJKIG_01368 1.8e-209 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
IGGGJKIG_01369 4.7e-76 M transferase activity, transferring glycosyl groups
IGGGJKIG_01370 2.2e-88 cps3F
IGGGJKIG_01371 3e-28 M biosynthesis protein
IGGGJKIG_01372 2.4e-77 rgpB GT2 M Glycosyl transferase family 2
IGGGJKIG_01373 4.4e-66 S Glycosyltransferase like family
IGGGJKIG_01374 4.9e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
IGGGJKIG_01375 3.1e-73 S Acyltransferase family
IGGGJKIG_01376 3.6e-35
IGGGJKIG_01377 1.6e-71 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IGGGJKIG_01378 6.9e-165 ykoT GT2 M Glycosyl transferase family 2
IGGGJKIG_01379 7.9e-31 S integral membrane protein
IGGGJKIG_01380 1.5e-08 S integral membrane protein
IGGGJKIG_01381 1.2e-114 rlpA M PFAM NLP P60 protein
IGGGJKIG_01382 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IGGGJKIG_01383 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IGGGJKIG_01384 2.6e-58 yodB K Transcriptional regulator, HxlR family
IGGGJKIG_01385 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IGGGJKIG_01386 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IGGGJKIG_01387 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IGGGJKIG_01388 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IGGGJKIG_01389 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IGGGJKIG_01390 4.4e-231 V MatE
IGGGJKIG_01391 7.4e-267 yjeM E Amino Acid
IGGGJKIG_01392 1.6e-277 arlS 2.7.13.3 T Histidine kinase
IGGGJKIG_01393 1.5e-121 K response regulator
IGGGJKIG_01394 1.9e-34 T Toxin-antitoxin system, toxin component, MazF family
IGGGJKIG_01395 8.9e-37
IGGGJKIG_01397 0.0 snf 2.7.11.1 KL domain protein
IGGGJKIG_01398 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
IGGGJKIG_01399 1.7e-176 M Glycosyl hydrolases family 25
IGGGJKIG_01400 7.6e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IGGGJKIG_01401 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IGGGJKIG_01403 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
IGGGJKIG_01404 1.3e-293 lmrA 3.6.3.44 V ABC transporter
IGGGJKIG_01406 6.8e-130 K response regulator
IGGGJKIG_01407 0.0 vicK 2.7.13.3 T Histidine kinase
IGGGJKIG_01408 2.1e-246 yycH S YycH protein
IGGGJKIG_01409 2.7e-149 yycI S YycH protein
IGGGJKIG_01410 3.8e-153 vicX 3.1.26.11 S domain protein
IGGGJKIG_01411 9.6e-215 htrA 3.4.21.107 O serine protease
IGGGJKIG_01412 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IGGGJKIG_01413 4.7e-177 ABC-SBP S ABC transporter
IGGGJKIG_01414 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IGGGJKIG_01416 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IGGGJKIG_01417 6.1e-198 XK27_09615 S reductase
IGGGJKIG_01418 1.2e-100 nqr 1.5.1.36 S reductase
IGGGJKIG_01420 1.3e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IGGGJKIG_01421 1.7e-182 K Transcriptional regulator, LacI family
IGGGJKIG_01422 6.8e-259 G Major Facilitator
IGGGJKIG_01423 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IGGGJKIG_01424 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IGGGJKIG_01425 4.6e-97 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IGGGJKIG_01426 9.3e-65 gntR1 K Transcriptional regulator, GntR family
IGGGJKIG_01427 1.2e-157 V ABC transporter, ATP-binding protein
IGGGJKIG_01428 6.7e-114
IGGGJKIG_01429 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
IGGGJKIG_01430 2.4e-99 S Pfam:DUF3816
IGGGJKIG_01431 0.0 clpE O Belongs to the ClpA ClpB family
IGGGJKIG_01432 2.9e-27
IGGGJKIG_01433 2.7e-39 ptsH G phosphocarrier protein HPR
IGGGJKIG_01434 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IGGGJKIG_01435 5.1e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IGGGJKIG_01436 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
IGGGJKIG_01437 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IGGGJKIG_01438 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
IGGGJKIG_01439 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IGGGJKIG_01440 3.7e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IGGGJKIG_01441 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IGGGJKIG_01442 2e-194 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IGGGJKIG_01443 1.8e-184 M family 8
IGGGJKIG_01444 5.4e-181 GT2 M Glycosyltransferase like family 2
IGGGJKIG_01445 7.5e-183 M Glycosyl transferase, family 2
IGGGJKIG_01446 2e-233 S Psort location CytoplasmicMembrane, score 9.99
IGGGJKIG_01447 5.1e-238 S polysaccharide biosynthetic process
IGGGJKIG_01448 1.4e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
IGGGJKIG_01449 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IGGGJKIG_01450 2.2e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IGGGJKIG_01451 8.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
IGGGJKIG_01452 0.0 helD 3.6.4.12 L DNA helicase
IGGGJKIG_01453 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IGGGJKIG_01455 4.8e-257 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IGGGJKIG_01456 4.3e-267 yfnA E amino acid
IGGGJKIG_01457 5.4e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IGGGJKIG_01458 5e-44 1.3.5.4 S FMN binding
IGGGJKIG_01459 5.4e-220 norA EGP Major facilitator Superfamily
IGGGJKIG_01460 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
IGGGJKIG_01461 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IGGGJKIG_01462 8.1e-154 KT YcbB domain
IGGGJKIG_01463 1.9e-302 xylB 2.7.1.17 G Belongs to the FGGY kinase family
IGGGJKIG_01464 7.6e-271 xylA 5.3.1.5 G Belongs to the xylose isomerase family
IGGGJKIG_01465 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
IGGGJKIG_01466 2.8e-45 pgdA 3.5.1.104 G polysaccharide deacetylase
IGGGJKIG_01467 0.0 3.2.1.55 GH51 G Right handed beta helix region
IGGGJKIG_01468 1.6e-290 xynT G MFS/sugar transport protein
IGGGJKIG_01474 5.7e-11 K Cro/C1-type HTH DNA-binding domain
IGGGJKIG_01476 9.8e-120 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
IGGGJKIG_01477 1.7e-156 L hmm pf00665
IGGGJKIG_01478 1.7e-128 L Helix-turn-helix domain
IGGGJKIG_01479 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IGGGJKIG_01480 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IGGGJKIG_01481 2.8e-255 yagE E amino acid
IGGGJKIG_01482 3.4e-85 dps P Belongs to the Dps family
IGGGJKIG_01483 0.0 pacL 3.6.3.8 P P-type ATPase
IGGGJKIG_01484 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IGGGJKIG_01485 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IGGGJKIG_01486 1.7e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IGGGJKIG_01487 4.5e-146 potB P ABC transporter permease
IGGGJKIG_01488 1.9e-139 potC P ABC transporter permease
IGGGJKIG_01489 4.3e-208 potD P ABC transporter
IGGGJKIG_01490 8.1e-230
IGGGJKIG_01491 7.2e-234 EGP Sugar (and other) transporter
IGGGJKIG_01492 6e-255 yfnA E Amino Acid
IGGGJKIG_01493 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IGGGJKIG_01494 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
IGGGJKIG_01495 1.5e-82 zur P Belongs to the Fur family
IGGGJKIG_01496 4e-17 3.2.1.14 GH18
IGGGJKIG_01497 8.3e-151
IGGGJKIG_01498 5.8e-39 pspC KT PspC domain protein
IGGGJKIG_01499 1.6e-94 K Transcriptional regulator (TetR family)
IGGGJKIG_01500 5.3e-221 V domain protein
IGGGJKIG_01501 7.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IGGGJKIG_01503 6.6e-35 S Transglycosylase associated protein
IGGGJKIG_01504 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IGGGJKIG_01505 4.2e-126 3.1.3.73 G phosphoglycerate mutase
IGGGJKIG_01506 3.4e-115 dedA S SNARE associated Golgi protein
IGGGJKIG_01507 0.0 helD 3.6.4.12 L DNA helicase
IGGGJKIG_01508 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
IGGGJKIG_01509 4.7e-157 EG EamA-like transporter family
IGGGJKIG_01510 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IGGGJKIG_01511 3.1e-175 coaA 2.7.1.33 F Pantothenic acid kinase
IGGGJKIG_01512 5.6e-225 S cog cog1373
IGGGJKIG_01514 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IGGGJKIG_01515 4.9e-224 oxlT P Major Facilitator Superfamily
IGGGJKIG_01516 3.3e-158 spoU 2.1.1.185 J Methyltransferase
IGGGJKIG_01517 2.8e-24
IGGGJKIG_01519 2.4e-31 S CAAX protease self-immunity
IGGGJKIG_01520 3.1e-59
IGGGJKIG_01521 5.6e-204
IGGGJKIG_01523 3e-44
IGGGJKIG_01524 1.7e-33 S RelB antitoxin
IGGGJKIG_01525 3.1e-104 L Integrase
IGGGJKIG_01526 2.6e-169 yjjC V ABC transporter
IGGGJKIG_01527 1.7e-293 M Exporter of polyketide antibiotics
IGGGJKIG_01528 7.3e-115 K Transcriptional regulator
IGGGJKIG_01529 6.7e-99 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
IGGGJKIG_01530 4.1e-16 UW LPXTG-motif cell wall anchor domain protein
IGGGJKIG_01531 8.5e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IGGGJKIG_01532 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
IGGGJKIG_01533 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IGGGJKIG_01534 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IGGGJKIG_01535 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IGGGJKIG_01536 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IGGGJKIG_01537 5.8e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IGGGJKIG_01538 5.5e-217 patA 2.6.1.1 E Aminotransferase
IGGGJKIG_01539 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IGGGJKIG_01540 6.8e-121 radC L DNA repair protein
IGGGJKIG_01541 1.7e-179 mreB D cell shape determining protein MreB
IGGGJKIG_01542 2.2e-151 mreC M Involved in formation and maintenance of cell shape
IGGGJKIG_01543 1.2e-91 mreD M rod shape-determining protein MreD
IGGGJKIG_01544 3.2e-102 glnP P ABC transporter permease
IGGGJKIG_01545 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IGGGJKIG_01546 2.6e-160 aatB ET ABC transporter substrate-binding protein
IGGGJKIG_01547 1.6e-230 ymfF S Peptidase M16 inactive domain protein
IGGGJKIG_01548 3.2e-250 ymfH S Peptidase M16
IGGGJKIG_01549 7.4e-141 ymfM S Helix-turn-helix domain
IGGGJKIG_01550 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IGGGJKIG_01551 2.2e-72
IGGGJKIG_01552 1.7e-266 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
IGGGJKIG_01553 2.3e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
IGGGJKIG_01554 9.6e-263 M domain protein
IGGGJKIG_01555 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IGGGJKIG_01556 8.8e-209 G Major Facilitator
IGGGJKIG_01557 7.2e-43 G Major Facilitator
IGGGJKIG_01558 1.2e-258 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IGGGJKIG_01559 2.4e-153 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IGGGJKIG_01560 1.9e-280 2.4.1.5 GH13 G Glycosyl hydrolase family 70
IGGGJKIG_01561 2e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IGGGJKIG_01562 3.4e-250 mmuP E amino acid
IGGGJKIG_01564 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IGGGJKIG_01565 5.1e-173 scrR K Transcriptional regulator, LacI family
IGGGJKIG_01566 3e-24
IGGGJKIG_01567 8.2e-103
IGGGJKIG_01568 5.8e-214 yttB EGP Major facilitator Superfamily
IGGGJKIG_01569 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
IGGGJKIG_01570 2.2e-87
IGGGJKIG_01571 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
IGGGJKIG_01572 6.6e-262 S Putative peptidoglycan binding domain
IGGGJKIG_01573 1.3e-96 yslB S Protein of unknown function (DUF2507)
IGGGJKIG_01574 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IGGGJKIG_01575 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IGGGJKIG_01576 4.4e-94 S Phosphoesterase
IGGGJKIG_01577 3.6e-76 ykuL S (CBS) domain
IGGGJKIG_01578 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
IGGGJKIG_01579 3.4e-147 ykuT M mechanosensitive ion channel
IGGGJKIG_01580 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IGGGJKIG_01581 3.5e-26
IGGGJKIG_01582 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IGGGJKIG_01583 1.9e-181 ccpA K catabolite control protein A
IGGGJKIG_01584 1.9e-134
IGGGJKIG_01585 3.5e-132 yebC K Transcriptional regulatory protein
IGGGJKIG_01586 2.6e-180 comGA NU Type II IV secretion system protein
IGGGJKIG_01587 9.2e-113 comGB NU type II secretion system
IGGGJKIG_01588 2.6e-53 comGB NU type II secretion system
IGGGJKIG_01589 2.1e-46 comGC U competence protein ComGC
IGGGJKIG_01590 8.3e-78 NU general secretion pathway protein
IGGGJKIG_01591 2.7e-40
IGGGJKIG_01592 1e-45
IGGGJKIG_01594 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
IGGGJKIG_01595 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IGGGJKIG_01596 2.2e-113 S Calcineurin-like phosphoesterase
IGGGJKIG_01597 1.3e-93 yutD S Protein of unknown function (DUF1027)
IGGGJKIG_01598 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IGGGJKIG_01599 2.4e-105 S Protein of unknown function (DUF1461)
IGGGJKIG_01600 5.5e-110 dedA S SNARE-like domain protein
IGGGJKIG_01601 1.1e-75 KV of ABC transporters with duplicated ATPase domains
IGGGJKIG_01602 5.4e-43
IGGGJKIG_01603 5.4e-202
IGGGJKIG_01605 6.8e-50 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IGGGJKIG_01606 2.9e-42 relB L RelB antitoxin
IGGGJKIG_01607 3.8e-94 L Integrase
IGGGJKIG_01609 2.1e-163 tetP J Elongation factor G, domain IV
IGGGJKIG_01610 4.6e-41 rpmE2 J Ribosomal protein L31
IGGGJKIG_01611 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IGGGJKIG_01612 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IGGGJKIG_01613 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IGGGJKIG_01614 3e-66 ywiB S Domain of unknown function (DUF1934)
IGGGJKIG_01615 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IGGGJKIG_01616 5e-270 ywfO S HD domain protein
IGGGJKIG_01617 7.9e-146 yxeH S hydrolase
IGGGJKIG_01618 2.1e-49
IGGGJKIG_01619 9.2e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IGGGJKIG_01620 1.1e-115 dck 2.7.1.74 F deoxynucleoside kinase
IGGGJKIG_01621 8.5e-113
IGGGJKIG_01622 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
IGGGJKIG_01623 7.5e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGGGJKIG_01624 2.1e-32
IGGGJKIG_01625 4.5e-112 S CAAX protease self-immunity
IGGGJKIG_01626 1.9e-43
IGGGJKIG_01628 5.4e-68
IGGGJKIG_01629 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IGGGJKIG_01630 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IGGGJKIG_01631 4e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
IGGGJKIG_01632 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IGGGJKIG_01633 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
IGGGJKIG_01634 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
IGGGJKIG_01635 1.8e-43
IGGGJKIG_01636 1.2e-32
IGGGJKIG_01638 1e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IGGGJKIG_01639 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IGGGJKIG_01640 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IGGGJKIG_01641 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IGGGJKIG_01642 3.5e-40 yheA S Belongs to the UPF0342 family
IGGGJKIG_01643 1.8e-220 yhaO L Ser Thr phosphatase family protein
IGGGJKIG_01644 0.0 L AAA domain
IGGGJKIG_01645 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IGGGJKIG_01647 1.2e-76 hit FG histidine triad
IGGGJKIG_01648 3.9e-136 ecsA V ABC transporter, ATP-binding protein
IGGGJKIG_01649 5.1e-218 ecsB U ABC transporter
IGGGJKIG_01650 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IGGGJKIG_01651 7.7e-27 S YSIRK type signal peptide
IGGGJKIG_01652 2.5e-35 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
IGGGJKIG_01653 9.5e-256 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
IGGGJKIG_01654 2.3e-145 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IGGGJKIG_01655 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IGGGJKIG_01656 8.8e-184 iolS C Aldo keto reductase
IGGGJKIG_01657 1.2e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
IGGGJKIG_01658 7.5e-58 ytzB S Small secreted protein
IGGGJKIG_01659 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IGGGJKIG_01660 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IGGGJKIG_01661 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
IGGGJKIG_01662 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IGGGJKIG_01663 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IGGGJKIG_01664 1.9e-119 ybhL S Belongs to the BI1 family
IGGGJKIG_01665 2e-115 yoaK S Protein of unknown function (DUF1275)
IGGGJKIG_01666 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IGGGJKIG_01667 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IGGGJKIG_01668 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IGGGJKIG_01669 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IGGGJKIG_01670 1.4e-203 dnaB L replication initiation and membrane attachment
IGGGJKIG_01671 1.1e-170 dnaI L Primosomal protein DnaI
IGGGJKIG_01672 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IGGGJKIG_01673 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IGGGJKIG_01674 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IGGGJKIG_01675 1.8e-95 yqeG S HAD phosphatase, family IIIA
IGGGJKIG_01676 1.4e-217 yqeH S Ribosome biogenesis GTPase YqeH
IGGGJKIG_01677 1.9e-47 yhbY J RNA-binding protein
IGGGJKIG_01678 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IGGGJKIG_01679 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IGGGJKIG_01680 6.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IGGGJKIG_01681 1.7e-139 yqeM Q Methyltransferase
IGGGJKIG_01682 4.6e-213 ylbM S Belongs to the UPF0348 family
IGGGJKIG_01683 9.3e-98 yceD S Uncharacterized ACR, COG1399
IGGGJKIG_01684 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IGGGJKIG_01685 2.9e-96 S reductase
IGGGJKIG_01686 1.9e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
IGGGJKIG_01687 3e-147 E Glyoxalase-like domain
IGGGJKIG_01688 8.6e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IGGGJKIG_01689 5.2e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IGGGJKIG_01690 5.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IGGGJKIG_01691 4.4e-129 V ABC transporter
IGGGJKIG_01692 2.5e-212 bacI V MacB-like periplasmic core domain
IGGGJKIG_01693 2.7e-68 L Belongs to the 'phage' integrase family
IGGGJKIG_01694 5.8e-239 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
IGGGJKIG_01695 2.5e-130 IQ Dehydrogenase reductase
IGGGJKIG_01696 2.9e-37
IGGGJKIG_01697 4.8e-114 ywnB S NAD(P)H-binding
IGGGJKIG_01698 7.7e-38 S Cytochrome b5-like Heme/Steroid binding domain
IGGGJKIG_01699 1.2e-255 nhaC C Na H antiporter NhaC
IGGGJKIG_01700 6e-109 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IGGGJKIG_01701 1.3e-61 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IGGGJKIG_01703 5.5e-228 L COG3547 Transposase and inactivated derivatives
IGGGJKIG_01704 0.0 L Helicase C-terminal domain protein
IGGGJKIG_01705 1.7e-96 L Helicase C-terminal domain protein
IGGGJKIG_01706 9.9e-75 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
IGGGJKIG_01707 3.8e-176 S Aldo keto reductase
IGGGJKIG_01709 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IGGGJKIG_01710 1.1e-36 psiE S Phosphate-starvation-inducible E
IGGGJKIG_01711 1e-101 ydeN S Serine hydrolase
IGGGJKIG_01712 1.5e-132 K Transcriptional regulatory protein, C-terminal domain protein
IGGGJKIG_01713 8.6e-159 pstS P Phosphate
IGGGJKIG_01714 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
IGGGJKIG_01715 4.7e-152 pstA P Phosphate transport system permease protein PstA
IGGGJKIG_01716 8.9e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IGGGJKIG_01717 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
IGGGJKIG_01718 2.7e-144
IGGGJKIG_01719 4.4e-118 ydaM M Glycosyl transferase
IGGGJKIG_01720 1.7e-53 ogt 2.1.1.63 L Methyltransferase
IGGGJKIG_01721 1.1e-74 pnb C nitroreductase
IGGGJKIG_01722 2.1e-91
IGGGJKIG_01723 1.4e-90 S B3 4 domain
IGGGJKIG_01724 2.1e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
IGGGJKIG_01725 7.9e-158 amtB P ammonium transporter
IGGGJKIG_01726 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IGGGJKIG_01728 1.3e-46
IGGGJKIG_01729 3.2e-96 S PFAM Archaeal ATPase
IGGGJKIG_01730 5.9e-121 L Belongs to the 'phage' integrase family
IGGGJKIG_01731 1.9e-10
IGGGJKIG_01737 0.0 L PLD-like domain
IGGGJKIG_01739 9e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IGGGJKIG_01740 2.9e-193 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IGGGJKIG_01741 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
IGGGJKIG_01744 3.1e-13 L Replication initiation factor
IGGGJKIG_01747 6.8e-48 S C4-dicarboxylate anaerobic carrier
IGGGJKIG_01748 1.3e-21
IGGGJKIG_01749 9.6e-39 sugE U Multidrug resistance protein
IGGGJKIG_01751 4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
IGGGJKIG_01752 1.3e-20
IGGGJKIG_01753 8.1e-90 ntd 2.4.2.6 F Nucleoside
IGGGJKIG_01754 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
IGGGJKIG_01755 1.6e-45 yrvD S Pfam:DUF1049
IGGGJKIG_01757 1.1e-35 S Phage derived protein Gp49-like (DUF891)
IGGGJKIG_01758 8.5e-20 K Helix-turn-helix XRE-family like proteins
IGGGJKIG_01759 1.7e-78 I alpha/beta hydrolase fold
IGGGJKIG_01760 1.1e-113 frnE Q DSBA-like thioredoxin domain
IGGGJKIG_01761 4.6e-49
IGGGJKIG_01762 6.7e-278 pipD E Dipeptidase
IGGGJKIG_01763 0.0 yjbQ P TrkA C-terminal domain protein
IGGGJKIG_01764 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IGGGJKIG_01765 6.2e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IGGGJKIG_01766 2.9e-82
IGGGJKIG_01767 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IGGGJKIG_01768 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IGGGJKIG_01769 5.4e-245 steT E amino acid
IGGGJKIG_01770 1.1e-161 rapZ S Displays ATPase and GTPase activities
IGGGJKIG_01771 4.2e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IGGGJKIG_01772 4e-170 whiA K May be required for sporulation
IGGGJKIG_01774 8.8e-15
IGGGJKIG_01775 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IGGGJKIG_01777 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IGGGJKIG_01778 3.2e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IGGGJKIG_01779 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IGGGJKIG_01780 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IGGGJKIG_01781 7.1e-248 yifK E Amino acid permease
IGGGJKIG_01782 2.4e-289 clcA P chloride
IGGGJKIG_01783 1.8e-34 secG U Preprotein translocase
IGGGJKIG_01784 5.7e-146 est 3.1.1.1 S Serine aminopeptidase, S33
IGGGJKIG_01785 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IGGGJKIG_01786 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IGGGJKIG_01787 6.3e-105 yxjI
IGGGJKIG_01788 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IGGGJKIG_01789 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IGGGJKIG_01790 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IGGGJKIG_01791 7.4e-86 K Acetyltransferase (GNAT) domain
IGGGJKIG_01792 4.4e-76 S PAS domain
IGGGJKIG_01793 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
IGGGJKIG_01794 1.6e-168 murB 1.3.1.98 M Cell wall formation
IGGGJKIG_01795 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IGGGJKIG_01796 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IGGGJKIG_01797 4.8e-249 fucP G Major Facilitator Superfamily
IGGGJKIG_01798 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IGGGJKIG_01799 2e-126 ybbR S YbbR-like protein
IGGGJKIG_01800 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IGGGJKIG_01801 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IGGGJKIG_01802 8.7e-53
IGGGJKIG_01803 0.0 oatA I Acyltransferase
IGGGJKIG_01804 2.3e-81 K Transcriptional regulator
IGGGJKIG_01805 2e-149 XK27_02985 S Cof-like hydrolase
IGGGJKIG_01806 2.8e-79 lytE M Lysin motif
IGGGJKIG_01808 5.7e-132 K response regulator
IGGGJKIG_01809 2.6e-272 yclK 2.7.13.3 T Histidine kinase
IGGGJKIG_01810 2.6e-155 glcU U sugar transport
IGGGJKIG_01811 1.3e-92 lacA 2.3.1.79 S Transferase hexapeptide repeat
IGGGJKIG_01812 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
IGGGJKIG_01813 1.3e-28
IGGGJKIG_01814 1.6e-216 xylR GK ROK family
IGGGJKIG_01816 1.3e-260 xylT EGP Major facilitator Superfamily
IGGGJKIG_01817 4.5e-89 rhaS2 K Transcriptional regulator, AraC family
IGGGJKIG_01818 3.4e-44 vsr L DNA mismatch endonuclease Vsr
IGGGJKIG_01819 6.2e-149 2.1.1.37 H C-5 cytosine-specific DNA methylase
IGGGJKIG_01820 7.9e-56 L AlwI restriction endonuclease
IGGGJKIG_01821 5.5e-45 L AlwI restriction endonuclease
IGGGJKIG_01824 4.6e-22 S Plasmid replication protein
IGGGJKIG_01825 4e-47 L Helix-turn-helix domain
IGGGJKIG_01826 3.6e-123 L hmm pf00665
IGGGJKIG_01828 8e-157 metQ_4 P Belongs to the nlpA lipoprotein family
IGGGJKIG_01829 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IGGGJKIG_01830 2.3e-105 O Zinc-dependent metalloprotease
IGGGJKIG_01831 6.8e-09 O Zinc-dependent metalloprotease
IGGGJKIG_01832 4.1e-115 S Membrane
IGGGJKIG_01833 1.2e-225 clcA_2 P Chloride transporter, ClC family
IGGGJKIG_01834 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IGGGJKIG_01835 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
IGGGJKIG_01841 8.8e-117 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IGGGJKIG_01842 1.7e-21
IGGGJKIG_01843 7.1e-135 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IGGGJKIG_01844 3.7e-73 S Chloramphenicol phosphotransferase-like protein
IGGGJKIG_01845 7.7e-168 aadK G Streptomycin adenylyltransferase
IGGGJKIG_01846 4.6e-46
IGGGJKIG_01847 5.5e-153 EG EamA-like transporter family
IGGGJKIG_01848 9.4e-118 L Integrase
IGGGJKIG_01849 1.2e-157 rssA S Phospholipase, patatin family
IGGGJKIG_01850 1.1e-14 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
IGGGJKIG_01851 1.2e-232 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
IGGGJKIG_01852 4.3e-64 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IGGGJKIG_01853 5.9e-32 aatB ET PFAM extracellular solute-binding protein, family 3
IGGGJKIG_01854 3.5e-103 aatB ET PFAM extracellular solute-binding protein, family 3
IGGGJKIG_01855 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
IGGGJKIG_01856 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IGGGJKIG_01857 2.3e-116 yfbR S HD containing hydrolase-like enzyme
IGGGJKIG_01858 1.5e-13
IGGGJKIG_01859 2.1e-91
IGGGJKIG_01860 6.7e-66 K Transcriptional regulator, HxlR family
IGGGJKIG_01861 2.4e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IGGGJKIG_01862 3.8e-146 epsB M biosynthesis protein
IGGGJKIG_01863 8.5e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IGGGJKIG_01864 2.6e-115 rfbP M Bacterial sugar transferase
IGGGJKIG_01865 8.4e-84 KT Putative sugar diacid recognition
IGGGJKIG_01866 1.7e-219 EG GntP family permease
IGGGJKIG_01867 3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IGGGJKIG_01868 7.7e-58
IGGGJKIG_01870 1.5e-16 pre D plasmid recombination enzyme
IGGGJKIG_01871 6e-93 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
IGGGJKIG_01873 1.7e-50 S Plasmid replication protein
IGGGJKIG_01874 1.9e-113 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IGGGJKIG_01875 6.2e-30 pre D plasmid recombination enzyme
IGGGJKIG_01876 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IGGGJKIG_01877 3e-75
IGGGJKIG_01878 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IGGGJKIG_01879 1.5e-25
IGGGJKIG_01880 2.7e-263 S Uncharacterized protein conserved in bacteria (DUF2252)
IGGGJKIG_01881 3.6e-168 L transposase, IS605 OrfB family
IGGGJKIG_01882 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
IGGGJKIG_01883 3.3e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
IGGGJKIG_01884 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IGGGJKIG_01885 1.9e-161 mleR K LysR family
IGGGJKIG_01886 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IGGGJKIG_01887 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IGGGJKIG_01888 1.8e-267 frdC 1.3.5.4 C FAD binding domain
IGGGJKIG_01889 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
IGGGJKIG_01890 1e-159 mleR K LysR family
IGGGJKIG_01891 2e-250 yjjP S Putative threonine/serine exporter
IGGGJKIG_01892 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
IGGGJKIG_01893 2e-283 emrY EGP Major facilitator Superfamily
IGGGJKIG_01894 3.4e-188 I Alpha beta
IGGGJKIG_01895 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
IGGGJKIG_01896 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IGGGJKIG_01898 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IGGGJKIG_01899 9.5e-119 S Domain of unknown function (DUF4811)
IGGGJKIG_01900 2.7e-269 lmrB EGP Major facilitator Superfamily
IGGGJKIG_01901 4.9e-73 merR K MerR HTH family regulatory protein
IGGGJKIG_01902 2.5e-53
IGGGJKIG_01903 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IGGGJKIG_01904 2.1e-216 S CAAX protease self-immunity
IGGGJKIG_01905 1.4e-108 glnP P ABC transporter permease
IGGGJKIG_01906 4.2e-110 gluC P ABC transporter permease
IGGGJKIG_01907 7.5e-152 glnH ET ABC transporter
IGGGJKIG_01908 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IGGGJKIG_01909 5.5e-83 usp1 T Belongs to the universal stress protein A family
IGGGJKIG_01910 7.6e-110 S VIT family
IGGGJKIG_01911 5e-117 S membrane
IGGGJKIG_01912 2.6e-166 czcD P cation diffusion facilitator family transporter
IGGGJKIG_01913 1.1e-124 sirR K iron dependent repressor
IGGGJKIG_01914 3.5e-31 cspC K Cold shock protein
IGGGJKIG_01915 3.6e-129 thrE S Putative threonine/serine exporter
IGGGJKIG_01916 6.7e-81 S Threonine/Serine exporter, ThrE
IGGGJKIG_01917 2.7e-120 lssY 3.6.1.27 I phosphatase
IGGGJKIG_01918 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
IGGGJKIG_01919 1.5e-275 lysP E amino acid
IGGGJKIG_01920 1.3e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IGGGJKIG_01926 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IGGGJKIG_01927 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IGGGJKIG_01928 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IGGGJKIG_01929 3e-203 coiA 3.6.4.12 S Competence protein
IGGGJKIG_01930 1.7e-262 pipD E Dipeptidase
IGGGJKIG_01931 6.7e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGGGJKIG_01932 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGGGJKIG_01933 1.7e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IGGGJKIG_01934 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IGGGJKIG_01935 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IGGGJKIG_01936 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IGGGJKIG_01937 1.8e-50 L Resolvase, N terminal domain
IGGGJKIG_01938 2.7e-127 tesE Q hydratase
IGGGJKIG_01939 2e-116 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IGGGJKIG_01941 2e-78
IGGGJKIG_01942 2e-33
IGGGJKIG_01943 2.3e-50
IGGGJKIG_01944 7.8e-42
IGGGJKIG_01945 3.1e-38 S Phage gp6-like head-tail connector protein
IGGGJKIG_01946 5.7e-88 gpG
IGGGJKIG_01948 3.2e-171 XK27_00915 C Luciferase-like monooxygenase
IGGGJKIG_01949 5.7e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
IGGGJKIG_01950 7.3e-69 S Protein of unknown function (DUF3021)
IGGGJKIG_01951 6.4e-78 K LytTr DNA-binding domain
IGGGJKIG_01952 9.1e-92 K Acetyltransferase (GNAT) family
IGGGJKIG_01953 2.4e-54 repB L Initiator Replication protein
IGGGJKIG_01957 2.1e-93 S MobA/MobL family
IGGGJKIG_01960 2.6e-155 D CobQ CobB MinD ParA nucleotide binding domain protein
IGGGJKIG_01961 1.4e-41
IGGGJKIG_01963 1.3e-150 2.1.1.72, 3.1.21.3 V N-6 DNA Methylase
IGGGJKIG_01964 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
IGGGJKIG_01965 7.9e-35 copZ C Heavy-metal-associated domain
IGGGJKIG_01966 6.7e-93 dps P Belongs to the Dps family
IGGGJKIG_01967 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IGGGJKIG_01968 7.3e-193 L Transposase IS66 family
IGGGJKIG_01969 9.9e-61 XK27_01125 L PFAM IS66 Orf2 family protein
IGGGJKIG_01972 8.1e-47 XK27_01125 L PFAM IS66 Orf2 family protein
IGGGJKIG_01973 1.6e-34 L Transposase IS66 family
IGGGJKIG_01974 2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IGGGJKIG_01975 3.7e-165 S Alpha/beta hydrolase of unknown function (DUF915)
IGGGJKIG_01976 5.1e-125 srtA 3.4.22.70 M sortase family
IGGGJKIG_01977 1.6e-138 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IGGGJKIG_01978 1.8e-200 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IGGGJKIG_01979 5.7e-157 3.2.1.55 GH51 G Right handed beta helix region
IGGGJKIG_01980 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IGGGJKIG_01981 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IGGGJKIG_01982 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
IGGGJKIG_01983 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IGGGJKIG_01984 7e-93 lemA S LemA family
IGGGJKIG_01985 2.6e-158 htpX O Belongs to the peptidase M48B family
IGGGJKIG_01986 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IGGGJKIG_01987 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IGGGJKIG_01988 1.1e-126 L PFAM Integrase catalytic region
IGGGJKIG_01989 3.7e-144 sprD D Domain of Unknown Function (DUF1542)
IGGGJKIG_01990 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
IGGGJKIG_01991 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IGGGJKIG_01992 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGGGJKIG_01993 3.7e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
IGGGJKIG_01994 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IGGGJKIG_01996 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IGGGJKIG_01997 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IGGGJKIG_01998 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
IGGGJKIG_01999 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
IGGGJKIG_02000 1.8e-242 codA 3.5.4.1 F cytosine deaminase
IGGGJKIG_02001 3.1e-147 tesE Q hydratase
IGGGJKIG_02002 4e-113 S (CBS) domain
IGGGJKIG_02003 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IGGGJKIG_02004 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IGGGJKIG_02005 8.1e-39 yabO J S4 domain protein
IGGGJKIG_02006 3.3e-56 divIC D Septum formation initiator
IGGGJKIG_02007 9.8e-67 yabR J RNA binding
IGGGJKIG_02008 1.1e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IGGGJKIG_02009 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IGGGJKIG_02010 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IGGGJKIG_02011 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IGGGJKIG_02012 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IGGGJKIG_02013 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IGGGJKIG_02014 5.5e-280 O Arylsulfotransferase (ASST)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)