ORF_ID e_value Gene_name EC_number CAZy COGs Description
IEDFAACK_00001 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IEDFAACK_00002 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IEDFAACK_00003 2.4e-33 yaaA S S4 domain
IEDFAACK_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IEDFAACK_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
IEDFAACK_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEDFAACK_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEDFAACK_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
IEDFAACK_00011 9.6e-180 yaaC S YaaC-like Protein
IEDFAACK_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IEDFAACK_00013 1.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IEDFAACK_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IEDFAACK_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IEDFAACK_00016 3.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IEDFAACK_00017 1.3e-09
IEDFAACK_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
IEDFAACK_00019 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
IEDFAACK_00020 2.6e-212 yaaH M Glycoside Hydrolase Family
IEDFAACK_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
IEDFAACK_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IEDFAACK_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEDFAACK_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IEDFAACK_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IEDFAACK_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
IEDFAACK_00027 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
IEDFAACK_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
IEDFAACK_00031 1.7e-30 csfB S Inhibitor of sigma-G Gin
IEDFAACK_00032 2.2e-100 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IEDFAACK_00033 9.9e-203 yaaN P Belongs to the TelA family
IEDFAACK_00034 2.5e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
IEDFAACK_00035 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IEDFAACK_00036 2.2e-54 yaaQ S protein conserved in bacteria
IEDFAACK_00037 1.5e-71 yaaR S protein conserved in bacteria
IEDFAACK_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
IEDFAACK_00039 6.1e-146 yaaT S stage 0 sporulation protein
IEDFAACK_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
IEDFAACK_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
IEDFAACK_00042 1.5e-49 yazA L endonuclease containing a URI domain
IEDFAACK_00043 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IEDFAACK_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
IEDFAACK_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEDFAACK_00046 2.6e-143 tatD L hydrolase, TatD
IEDFAACK_00047 2e-167 rpfB GH23 T protein conserved in bacteria
IEDFAACK_00048 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IEDFAACK_00049 4.5e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IEDFAACK_00050 1.6e-136 yabG S peptidase
IEDFAACK_00051 7.8e-39 veg S protein conserved in bacteria
IEDFAACK_00052 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IEDFAACK_00053 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IEDFAACK_00054 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
IEDFAACK_00055 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IEDFAACK_00056 5.6e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IEDFAACK_00057 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEDFAACK_00058 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IEDFAACK_00059 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IEDFAACK_00060 2.4e-39 yabK S Peptide ABC transporter permease
IEDFAACK_00061 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IEDFAACK_00062 1.5e-92 spoVT K stage V sporulation protein
IEDFAACK_00063 1.1e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEDFAACK_00064 3.3e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IEDFAACK_00065 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IEDFAACK_00066 1.5e-49 yabP S Sporulation protein YabP
IEDFAACK_00067 9.5e-107 yabQ S spore cortex biosynthesis protein
IEDFAACK_00068 1.1e-44 divIC D Septum formation initiator
IEDFAACK_00069 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
IEDFAACK_00072 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
IEDFAACK_00073 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
IEDFAACK_00074 6.3e-185 KLT serine threonine protein kinase
IEDFAACK_00075 1.9e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IEDFAACK_00076 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IEDFAACK_00077 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEDFAACK_00078 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IEDFAACK_00079 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IEDFAACK_00080 7.7e-152 yacD 5.2.1.8 O peptidyl-prolyl isomerase
IEDFAACK_00081 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IEDFAACK_00082 1.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IEDFAACK_00083 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
IEDFAACK_00084 6.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
IEDFAACK_00085 5.9e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IEDFAACK_00086 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IEDFAACK_00087 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IEDFAACK_00088 4.1e-30 yazB K transcriptional
IEDFAACK_00089 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEDFAACK_00090 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IEDFAACK_00091 3.4e-39 S COG NOG14552 non supervised orthologous group
IEDFAACK_00096 2e-08
IEDFAACK_00101 3.4e-39 S COG NOG14552 non supervised orthologous group
IEDFAACK_00102 2.9e-76 ctsR K Belongs to the CtsR family
IEDFAACK_00103 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
IEDFAACK_00104 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IEDFAACK_00105 0.0 clpC O Belongs to the ClpA ClpB family
IEDFAACK_00106 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IEDFAACK_00107 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IEDFAACK_00108 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
IEDFAACK_00109 4.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IEDFAACK_00110 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IEDFAACK_00111 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEDFAACK_00112 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
IEDFAACK_00113 7.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEDFAACK_00114 4e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IEDFAACK_00115 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEDFAACK_00116 1.2e-88 yacP S RNA-binding protein containing a PIN domain
IEDFAACK_00117 4.4e-115 sigH K Belongs to the sigma-70 factor family
IEDFAACK_00118 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IEDFAACK_00119 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
IEDFAACK_00120 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IEDFAACK_00121 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IEDFAACK_00122 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IEDFAACK_00123 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IEDFAACK_00124 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
IEDFAACK_00125 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEDFAACK_00126 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEDFAACK_00127 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
IEDFAACK_00128 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IEDFAACK_00129 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IEDFAACK_00130 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IEDFAACK_00131 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IEDFAACK_00132 2.7e-182 ybaC 3.4.11.5 S Alpha/beta hydrolase family
IEDFAACK_00133 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IEDFAACK_00134 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IEDFAACK_00135 3e-105 rplD J Forms part of the polypeptide exit tunnel
IEDFAACK_00136 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IEDFAACK_00137 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IEDFAACK_00138 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IEDFAACK_00139 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IEDFAACK_00140 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IEDFAACK_00141 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IEDFAACK_00142 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IEDFAACK_00143 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IEDFAACK_00144 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IEDFAACK_00145 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IEDFAACK_00146 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IEDFAACK_00147 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEDFAACK_00148 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IEDFAACK_00149 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IEDFAACK_00150 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IEDFAACK_00151 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IEDFAACK_00152 1.9e-23 rpmD J Ribosomal protein L30
IEDFAACK_00153 1.8e-72 rplO J binds to the 23S rRNA
IEDFAACK_00154 9.3e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IEDFAACK_00155 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IEDFAACK_00156 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
IEDFAACK_00157 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IEDFAACK_00158 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IEDFAACK_00159 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IEDFAACK_00160 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IEDFAACK_00161 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEDFAACK_00162 3.6e-58 rplQ J Ribosomal protein L17
IEDFAACK_00163 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEDFAACK_00164 2.2e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEDFAACK_00165 3e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEDFAACK_00166 2.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IEDFAACK_00167 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IEDFAACK_00168 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
IEDFAACK_00169 1.2e-143 ybaJ Q Methyltransferase domain
IEDFAACK_00170 9.7e-66 ybaK S Protein of unknown function (DUF2521)
IEDFAACK_00171 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IEDFAACK_00172 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IEDFAACK_00173 1.2e-84 gerD
IEDFAACK_00174 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
IEDFAACK_00175 7.9e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
IEDFAACK_00176 3.4e-39 S COG NOG14552 non supervised orthologous group
IEDFAACK_00177 4.1e-20 S ORF located using Blastx
IEDFAACK_00180 2e-08
IEDFAACK_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
IEDFAACK_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
IEDFAACK_00188 6.7e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
IEDFAACK_00190 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
IEDFAACK_00191 4.1e-141 ybbA S Putative esterase
IEDFAACK_00192 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_00193 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_00194 1.3e-163 feuA P Iron-uptake system-binding protein
IEDFAACK_00195 9.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
IEDFAACK_00196 1.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
IEDFAACK_00197 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
IEDFAACK_00198 5.4e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
IEDFAACK_00199 4.9e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEDFAACK_00200 1.4e-150 ybbH K transcriptional
IEDFAACK_00201 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IEDFAACK_00202 1.9e-86 ybbJ J acetyltransferase
IEDFAACK_00203 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
IEDFAACK_00209 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
IEDFAACK_00210 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IEDFAACK_00211 4.6e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IEDFAACK_00212 5.7e-224 ybbR S protein conserved in bacteria
IEDFAACK_00213 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEDFAACK_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IEDFAACK_00215 1.8e-175 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IEDFAACK_00216 2.2e-119 adaA 3.2.2.21 K Transcriptional regulator
IEDFAACK_00217 5.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEDFAACK_00218 2.2e-274 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IEDFAACK_00219 0.0 ybcC S Belongs to the UPF0753 family
IEDFAACK_00220 1.6e-91 can 4.2.1.1 P carbonic anhydrase
IEDFAACK_00222 7.3e-46
IEDFAACK_00223 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
IEDFAACK_00224 5.1e-50 ybzH K Helix-turn-helix domain
IEDFAACK_00225 6.5e-202 ybcL EGP Major facilitator Superfamily
IEDFAACK_00226 6.9e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IEDFAACK_00227 8.5e-122 T Transcriptional regulatory protein, C terminal
IEDFAACK_00228 1.1e-170 T His Kinase A (phospho-acceptor) domain
IEDFAACK_00230 4.4e-138 KLT Protein tyrosine kinase
IEDFAACK_00231 7.7e-152 ybdN
IEDFAACK_00232 5.7e-214 ybdO S Domain of unknown function (DUF4885)
IEDFAACK_00233 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
IEDFAACK_00234 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
IEDFAACK_00235 4.9e-30 ybxH S Family of unknown function (DUF5370)
IEDFAACK_00236 1.2e-149 ybxI 3.5.2.6 V beta-lactamase
IEDFAACK_00237 5.1e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
IEDFAACK_00238 4.9e-41 ybyB
IEDFAACK_00239 3e-290 ybeC E amino acid
IEDFAACK_00240 5.3e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IEDFAACK_00241 7.3e-258 glpT G -transporter
IEDFAACK_00242 1.5e-34 S Protein of unknown function (DUF2651)
IEDFAACK_00243 7.4e-169 ybfA 3.4.15.5 K FR47-like protein
IEDFAACK_00244 6e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
IEDFAACK_00245 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
IEDFAACK_00246 4.5e-158 ybfH EG EamA-like transporter family
IEDFAACK_00247 2.3e-145 msmR K AraC-like ligand binding domain
IEDFAACK_00248 4.3e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IEDFAACK_00249 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
IEDFAACK_00251 1.4e-164 S Alpha/beta hydrolase family
IEDFAACK_00252 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEDFAACK_00253 2.7e-85 ybfM S SNARE associated Golgi protein
IEDFAACK_00254 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IEDFAACK_00255 4.6e-45 ybfN
IEDFAACK_00256 2.1e-252 S Erythromycin esterase
IEDFAACK_00257 3.3e-191 yceA S Belongs to the UPF0176 family
IEDFAACK_00258 1.1e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEDFAACK_00259 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEDFAACK_00260 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IEDFAACK_00261 4.9e-128 K UTRA
IEDFAACK_00263 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IEDFAACK_00264 8.2e-260 mmuP E amino acid
IEDFAACK_00265 1.5e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
IEDFAACK_00266 9.6e-256 agcS E Sodium alanine symporter
IEDFAACK_00267 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
IEDFAACK_00268 9.4e-229 phoQ 2.7.13.3 T Histidine kinase
IEDFAACK_00269 9e-170 glnL T Regulator
IEDFAACK_00270 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
IEDFAACK_00271 3.4e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IEDFAACK_00272 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
IEDFAACK_00273 6.5e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IEDFAACK_00274 2.1e-123 ycbG K FCD
IEDFAACK_00275 4.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
IEDFAACK_00276 1e-173 ycbJ S Macrolide 2'-phosphotransferase
IEDFAACK_00277 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
IEDFAACK_00278 5.3e-170 eamA1 EG spore germination
IEDFAACK_00279 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_00280 2.9e-168 T PhoQ Sensor
IEDFAACK_00281 5.9e-166 ycbN V ABC transporter, ATP-binding protein
IEDFAACK_00282 2.4e-111 S ABC-2 family transporter protein
IEDFAACK_00283 4.1e-52 ycbP S Protein of unknown function (DUF2512)
IEDFAACK_00284 2.2e-78 sleB 3.5.1.28 M Cell wall
IEDFAACK_00285 9.5e-135 ycbR T vWA found in TerF C terminus
IEDFAACK_00286 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
IEDFAACK_00287 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IEDFAACK_00288 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IEDFAACK_00289 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IEDFAACK_00290 1.2e-200 ycbU E Selenocysteine lyase
IEDFAACK_00291 5.8e-229 lmrB EGP the major facilitator superfamily
IEDFAACK_00292 7e-101 yxaF K Transcriptional regulator
IEDFAACK_00293 2.6e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IEDFAACK_00294 9.3e-102 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
IEDFAACK_00295 1.7e-58 S RDD family
IEDFAACK_00296 2.8e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
IEDFAACK_00297 3e-157 2.7.13.3 T GHKL domain
IEDFAACK_00298 1.1e-124 lytR_2 T LytTr DNA-binding domain
IEDFAACK_00299 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
IEDFAACK_00300 1e-199 natB CP ABC-2 family transporter protein
IEDFAACK_00301 1.3e-173 yccK C Aldo keto reductase
IEDFAACK_00302 6.6e-177 ycdA S Domain of unknown function (DUF5105)
IEDFAACK_00303 2.5e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
IEDFAACK_00304 2.6e-256 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
IEDFAACK_00305 1.3e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
IEDFAACK_00306 1.2e-173 S response regulator aspartate phosphatase
IEDFAACK_00307 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
IEDFAACK_00308 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
IEDFAACK_00309 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
IEDFAACK_00310 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IEDFAACK_00311 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IEDFAACK_00312 5e-187 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEDFAACK_00313 1.1e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
IEDFAACK_00314 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
IEDFAACK_00315 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
IEDFAACK_00316 6.3e-137 terC P Protein of unknown function (DUF475)
IEDFAACK_00317 0.0 yceG S Putative component of 'biosynthetic module'
IEDFAACK_00318 2e-192 yceH P Belongs to the TelA family
IEDFAACK_00319 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
IEDFAACK_00320 2e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
IEDFAACK_00321 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
IEDFAACK_00322 4.3e-228 proV 3.6.3.32 E glycine betaine
IEDFAACK_00323 1.3e-127 opuAB P glycine betaine
IEDFAACK_00324 1.2e-163 opuAC E glycine betaine
IEDFAACK_00325 5e-215 amhX S amidohydrolase
IEDFAACK_00326 1.6e-255 ycgA S Membrane
IEDFAACK_00327 1.2e-80 ycgB
IEDFAACK_00328 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
IEDFAACK_00329 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IEDFAACK_00330 4.7e-291 lctP C L-lactate permease
IEDFAACK_00331 8.7e-263 mdr EGP Major facilitator Superfamily
IEDFAACK_00332 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
IEDFAACK_00333 6.8e-113 ycgF E Lysine exporter protein LysE YggA
IEDFAACK_00334 1.3e-150 yqcI S YqcI/YcgG family
IEDFAACK_00335 1.8e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
IEDFAACK_00336 2.4e-112 ycgI S Domain of unknown function (DUF1989)
IEDFAACK_00337 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IEDFAACK_00338 2.3e-107 tmrB S AAA domain
IEDFAACK_00340 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IEDFAACK_00341 3.4e-143 yafE Q ubiE/COQ5 methyltransferase family
IEDFAACK_00342 7.9e-177 oxyR3 K LysR substrate binding domain
IEDFAACK_00343 2.1e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
IEDFAACK_00344 2.4e-144 ycgL S Predicted nucleotidyltransferase
IEDFAACK_00345 5.1e-170 ycgM E Proline dehydrogenase
IEDFAACK_00346 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IEDFAACK_00347 5.9e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEDFAACK_00348 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
IEDFAACK_00349 1.3e-146 ycgQ S membrane
IEDFAACK_00350 1.2e-139 ycgR S permeases
IEDFAACK_00351 3.2e-158 I alpha/beta hydrolase fold
IEDFAACK_00352 6e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IEDFAACK_00353 2.1e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IEDFAACK_00354 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
IEDFAACK_00355 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEDFAACK_00356 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IEDFAACK_00357 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
IEDFAACK_00358 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
IEDFAACK_00359 3.5e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
IEDFAACK_00360 5.1e-107 yciB M ErfK YbiS YcfS YnhG
IEDFAACK_00361 7.8e-227 yciC S GTPases (G3E family)
IEDFAACK_00362 1.2e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
IEDFAACK_00363 1.7e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IEDFAACK_00365 3.1e-75 yckC S membrane
IEDFAACK_00366 7.8e-52 yckD S Protein of unknown function (DUF2680)
IEDFAACK_00367 1.5e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFAACK_00368 1.1e-68 nin S Competence protein J (ComJ)
IEDFAACK_00369 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
IEDFAACK_00370 1.8e-184 tlpC 2.7.13.3 NT chemotaxis protein
IEDFAACK_00371 3.9e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
IEDFAACK_00372 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
IEDFAACK_00373 1.3e-63 hxlR K transcriptional
IEDFAACK_00374 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_00375 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_00376 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_00377 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
IEDFAACK_00378 5.7e-140 srfAD Q thioesterase
IEDFAACK_00379 3.7e-224 EGP Major Facilitator Superfamily
IEDFAACK_00380 3e-88 S YcxB-like protein
IEDFAACK_00381 1.7e-160 ycxC EG EamA-like transporter family
IEDFAACK_00382 1.7e-251 ycxD K GntR family transcriptional regulator
IEDFAACK_00383 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IEDFAACK_00384 9.7e-115 yczE S membrane
IEDFAACK_00385 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IEDFAACK_00386 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
IEDFAACK_00387 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IEDFAACK_00388 1.9e-161 bsdA K LysR substrate binding domain
IEDFAACK_00389 3.2e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IEDFAACK_00390 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IEDFAACK_00391 4e-39 bsdD 4.1.1.61 S response to toxic substance
IEDFAACK_00392 6.6e-81 yclD
IEDFAACK_00393 3.7e-41 yclE 3.4.11.5 S Alpha beta hydrolase
IEDFAACK_00394 7.1e-77 yclE 3.4.11.5 S Alpha beta hydrolase
IEDFAACK_00395 1.3e-263 dtpT E amino acid peptide transporter
IEDFAACK_00396 3.2e-293 yclG M Pectate lyase superfamily protein
IEDFAACK_00398 7.5e-281 gerKA EG Spore germination protein
IEDFAACK_00399 1.6e-230 gerKC S spore germination
IEDFAACK_00400 3e-196 gerKB F Spore germination protein
IEDFAACK_00401 7.3e-121 yclH P ABC transporter
IEDFAACK_00402 1.3e-202 yclI V ABC transporter (permease) YclI
IEDFAACK_00403 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_00404 1.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IEDFAACK_00405 1.6e-80 S aspartate phosphatase
IEDFAACK_00409 1.5e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
IEDFAACK_00410 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_00411 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_00412 2.4e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
IEDFAACK_00413 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
IEDFAACK_00414 1.6e-250 ycnB EGP Major facilitator Superfamily
IEDFAACK_00415 6.5e-154 ycnC K Transcriptional regulator
IEDFAACK_00416 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
IEDFAACK_00417 1.6e-45 ycnE S Monooxygenase
IEDFAACK_00418 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
IEDFAACK_00419 1.5e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEDFAACK_00420 2.8e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEDFAACK_00421 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IEDFAACK_00422 1.8e-148 glcU U Glucose uptake
IEDFAACK_00423 4.6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEDFAACK_00424 1.4e-99 ycnI S protein conserved in bacteria
IEDFAACK_00425 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
IEDFAACK_00426 4.7e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
IEDFAACK_00427 3.4e-53
IEDFAACK_00428 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
IEDFAACK_00429 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IEDFAACK_00430 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
IEDFAACK_00431 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
IEDFAACK_00433 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IEDFAACK_00434 3.7e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
IEDFAACK_00435 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IEDFAACK_00437 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IEDFAACK_00438 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
IEDFAACK_00439 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
IEDFAACK_00440 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
IEDFAACK_00441 1.4e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
IEDFAACK_00442 3.1e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
IEDFAACK_00443 2.7e-132 kipR K Transcriptional regulator
IEDFAACK_00444 3.5e-117 ycsK E anatomical structure formation involved in morphogenesis
IEDFAACK_00446 1.4e-49 yczJ S biosynthesis
IEDFAACK_00447 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
IEDFAACK_00448 8.1e-176 ydhF S Oxidoreductase
IEDFAACK_00449 0.0 mtlR K transcriptional regulator, MtlR
IEDFAACK_00450 3e-292 ydaB IQ acyl-CoA ligase
IEDFAACK_00451 1.7e-97 ydaC Q Methyltransferase domain
IEDFAACK_00452 4.5e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEDFAACK_00453 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
IEDFAACK_00454 6.1e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IEDFAACK_00455 6.8e-77 ydaG 1.4.3.5 S general stress protein
IEDFAACK_00456 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IEDFAACK_00457 3.6e-45 ydzA EGP Major facilitator Superfamily
IEDFAACK_00458 2.5e-74 lrpC K Transcriptional regulator
IEDFAACK_00459 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IEDFAACK_00460 4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
IEDFAACK_00461 2.5e-150 ydaK T Diguanylate cyclase, GGDEF domain
IEDFAACK_00462 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
IEDFAACK_00463 4.5e-233 ydaM M Glycosyl transferase family group 2
IEDFAACK_00464 0.0 ydaN S Bacterial cellulose synthase subunit
IEDFAACK_00465 0.0 ydaO E amino acid
IEDFAACK_00466 2.4e-44 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IEDFAACK_00467 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IEDFAACK_00468 9.4e-40
IEDFAACK_00469 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
IEDFAACK_00471 8.5e-58 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
IEDFAACK_00472 1.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
IEDFAACK_00474 2.6e-58 ydbB G Cupin domain
IEDFAACK_00475 1.8e-62 ydbC S Domain of unknown function (DUF4937
IEDFAACK_00476 2.3e-153 ydbD P Catalase
IEDFAACK_00477 1.3e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IEDFAACK_00478 8.1e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IEDFAACK_00479 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
IEDFAACK_00480 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEDFAACK_00481 4.4e-181 ydbI S AI-2E family transporter
IEDFAACK_00482 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
IEDFAACK_00483 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IEDFAACK_00484 2.7e-52 ydbL
IEDFAACK_00485 6.3e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
IEDFAACK_00486 1.1e-18 S Fur-regulated basic protein B
IEDFAACK_00487 2.2e-07 S Fur-regulated basic protein A
IEDFAACK_00488 1.3e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEDFAACK_00489 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IEDFAACK_00490 3.7e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IEDFAACK_00491 1.6e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IEDFAACK_00492 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IEDFAACK_00493 2.1e-82 ydbS S Bacterial PH domain
IEDFAACK_00494 8.6e-260 ydbT S Membrane
IEDFAACK_00495 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
IEDFAACK_00496 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IEDFAACK_00497 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
IEDFAACK_00498 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEDFAACK_00499 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IEDFAACK_00500 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
IEDFAACK_00501 1.3e-143 rsbR T Positive regulator of sigma-B
IEDFAACK_00502 5.2e-57 rsbS T antagonist
IEDFAACK_00503 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IEDFAACK_00504 7.1e-189 rsbU 3.1.3.3 KT phosphatase
IEDFAACK_00505 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
IEDFAACK_00506 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IEDFAACK_00507 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEDFAACK_00508 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
IEDFAACK_00509 0.0 yhgF K COG2183 Transcriptional accessory protein
IEDFAACK_00510 3.4e-82 ydcK S Belongs to the SprT family
IEDFAACK_00519 6e-64 S Bacterial protein of unknown function (DUF961)
IEDFAACK_00520 2.8e-263 ydcQ D Ftsk spoiiie family protein
IEDFAACK_00521 2.2e-201 nicK L Replication initiation factor
IEDFAACK_00523 3.3e-19 yddA
IEDFAACK_00524 3.6e-153 yddB S Conjugative transposon protein TcpC
IEDFAACK_00525 5.1e-40 yddC
IEDFAACK_00526 2e-94 yddD S TcpE family
IEDFAACK_00527 0.0 yddE S AAA-like domain
IEDFAACK_00528 4.9e-54 S Domain of unknown function (DUF1874)
IEDFAACK_00529 0.0 yddG S maturation of SSU-rRNA
IEDFAACK_00530 4.5e-188 yddH CBM50 M Lysozyme-like
IEDFAACK_00531 2.4e-84 yddI
IEDFAACK_00532 5.1e-63 S Domain of unknown function with cystatin-like fold (DUF4467)
IEDFAACK_00535 8.7e-30 cspL K Cold shock
IEDFAACK_00536 2.3e-78 carD K Transcription factor
IEDFAACK_00537 3.1e-30 ydzE EG spore germination
IEDFAACK_00538 9.9e-163 rhaS5 K AraC-like ligand binding domain
IEDFAACK_00539 1.4e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IEDFAACK_00540 1.2e-163 ydeE K AraC family transcriptional regulator
IEDFAACK_00541 6.2e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEDFAACK_00542 5.5e-218 ydeG EGP Major facilitator superfamily
IEDFAACK_00543 2.7e-45 ydeH
IEDFAACK_00544 5.1e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
IEDFAACK_00545 1.8e-100
IEDFAACK_00546 1.8e-153 ydeK EG -transporter
IEDFAACK_00547 2.4e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEDFAACK_00548 6e-73 maoC I N-terminal half of MaoC dehydratase
IEDFAACK_00549 1.8e-104 ydeN S Serine hydrolase
IEDFAACK_00550 8.9e-56 K HxlR-like helix-turn-helix
IEDFAACK_00551 1.6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IEDFAACK_00552 4.8e-69 ydeP K Transcriptional regulator
IEDFAACK_00553 1.4e-107 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
IEDFAACK_00554 1.5e-193 ydeR EGP Major facilitator Superfamily
IEDFAACK_00555 3.2e-104 ydeS K Transcriptional regulator
IEDFAACK_00556 2.4e-56 arsR K transcriptional
IEDFAACK_00557 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IEDFAACK_00558 9.8e-146 ydfB J GNAT acetyltransferase
IEDFAACK_00559 3e-149 ydfC EG EamA-like transporter family
IEDFAACK_00560 6.7e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEDFAACK_00561 4.2e-115 ydfE S Flavin reductase like domain
IEDFAACK_00562 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
IEDFAACK_00563 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEDFAACK_00565 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
IEDFAACK_00566 2.1e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEDFAACK_00567 0.0 ydfJ S drug exporters of the RND superfamily
IEDFAACK_00568 3.4e-174 S Alpha/beta hydrolase family
IEDFAACK_00569 8.5e-117 S Protein of unknown function (DUF554)
IEDFAACK_00570 9.2e-147 K Bacterial transcription activator, effector binding domain
IEDFAACK_00571 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEDFAACK_00572 1.1e-110 ydfN C nitroreductase
IEDFAACK_00573 4.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
IEDFAACK_00574 8.8e-63 mhqP S DoxX
IEDFAACK_00575 1.7e-54 traF CO Thioredoxin
IEDFAACK_00576 3.3e-14 ydgA S Spore germination protein gerPA/gerPF
IEDFAACK_00577 6.3e-29
IEDFAACK_00579 1.9e-99 ydfR S Protein of unknown function (DUF421)
IEDFAACK_00580 2.6e-121 ydfS S Protein of unknown function (DUF421)
IEDFAACK_00581 3.2e-74 cotP O Belongs to the small heat shock protein (HSP20) family
IEDFAACK_00582 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
IEDFAACK_00583 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
IEDFAACK_00584 1.3e-82 K Bacterial regulatory proteins, tetR family
IEDFAACK_00585 1.4e-51 S DoxX-like family
IEDFAACK_00586 4.6e-82 yycN 2.3.1.128 K Acetyltransferase
IEDFAACK_00587 9.8e-305 expZ S ABC transporter
IEDFAACK_00588 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
IEDFAACK_00589 4.7e-88 dinB S DinB family
IEDFAACK_00590 1.5e-78 K helix_turn_helix multiple antibiotic resistance protein
IEDFAACK_00591 0.0 ydgH S drug exporters of the RND superfamily
IEDFAACK_00592 1e-113 drgA C nitroreductase
IEDFAACK_00593 2.4e-69 ydgJ K Winged helix DNA-binding domain
IEDFAACK_00594 2.2e-208 tcaB EGP Major facilitator Superfamily
IEDFAACK_00595 1.2e-121 ydhB S membrane transporter protein
IEDFAACK_00596 3.2e-121 ydhC K FCD
IEDFAACK_00597 9e-242 ydhD M Glycosyl hydrolase
IEDFAACK_00598 1.3e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IEDFAACK_00599 5.1e-125
IEDFAACK_00600 9e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
IEDFAACK_00601 1.1e-67 frataxin S Domain of unknown function (DU1801)
IEDFAACK_00603 8.6e-84 K Acetyltransferase (GNAT) domain
IEDFAACK_00604 1.3e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IEDFAACK_00605 9.4e-98 ydhK M Protein of unknown function (DUF1541)
IEDFAACK_00606 4.6e-200 pbuE EGP Major facilitator Superfamily
IEDFAACK_00607 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
IEDFAACK_00608 5.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
IEDFAACK_00609 4.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFAACK_00610 9e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFAACK_00611 1.2e-132 ydhQ K UTRA
IEDFAACK_00612 2.4e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
IEDFAACK_00613 1.3e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
IEDFAACK_00614 6.4e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
IEDFAACK_00615 4.6e-157 ydhU P Catalase
IEDFAACK_00618 3.4e-39 S COG NOG14552 non supervised orthologous group
IEDFAACK_00619 7.8e-08
IEDFAACK_00621 1.8e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IEDFAACK_00622 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
IEDFAACK_00623 4.9e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
IEDFAACK_00624 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IEDFAACK_00625 5.2e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IEDFAACK_00626 0.0 ydiF S ABC transporter
IEDFAACK_00627 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IEDFAACK_00628 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IEDFAACK_00629 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IEDFAACK_00630 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IEDFAACK_00631 2.9e-27 ydiK S Domain of unknown function (DUF4305)
IEDFAACK_00632 7.9e-129 ydiL S CAAX protease self-immunity
IEDFAACK_00633 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IEDFAACK_00634 3.7e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IEDFAACK_00635 4.9e-88 ydjC S alpha beta
IEDFAACK_00636 0.0 K NB-ARC domain
IEDFAACK_00637 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
IEDFAACK_00638 1.9e-253 gutA G MFS/sugar transport protein
IEDFAACK_00639 1.2e-174 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
IEDFAACK_00640 8.7e-114 pspA KT Phage shock protein A
IEDFAACK_00641 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEDFAACK_00642 6.5e-134 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
IEDFAACK_00643 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
IEDFAACK_00644 3.7e-193 S Ion transport 2 domain protein
IEDFAACK_00645 1.7e-257 iolT EGP Major facilitator Superfamily
IEDFAACK_00646 1.5e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
IEDFAACK_00647 4.5e-64 ydjM M Lytic transglycolase
IEDFAACK_00648 9.1e-155 ydjN U Involved in the tonB-independent uptake of proteins
IEDFAACK_00650 1.4e-34 ydjO S Cold-inducible protein YdjO
IEDFAACK_00651 2.1e-154 ydjP I Alpha/beta hydrolase family
IEDFAACK_00652 1.3e-174 yeaA S Protein of unknown function (DUF4003)
IEDFAACK_00653 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
IEDFAACK_00654 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
IEDFAACK_00655 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEDFAACK_00656 5e-176 yeaC S COG0714 MoxR-like ATPases
IEDFAACK_00657 6.8e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IEDFAACK_00658 0.0 yebA E COG1305 Transglutaminase-like enzymes
IEDFAACK_00659 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IEDFAACK_00660 1e-211 pbuG S permease
IEDFAACK_00661 2.3e-118 yebC M Membrane
IEDFAACK_00663 8.9e-93 yebE S UPF0316 protein
IEDFAACK_00664 8e-28 yebG S NETI protein
IEDFAACK_00665 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IEDFAACK_00666 2.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IEDFAACK_00667 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IEDFAACK_00668 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IEDFAACK_00669 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEDFAACK_00670 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEDFAACK_00671 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEDFAACK_00672 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IEDFAACK_00673 1.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IEDFAACK_00674 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IEDFAACK_00675 2.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IEDFAACK_00676 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
IEDFAACK_00677 1e-72 K helix_turn_helix ASNC type
IEDFAACK_00678 3.7e-227 yjeH E Amino acid permease
IEDFAACK_00679 4.6e-27 S Protein of unknown function (DUF2892)
IEDFAACK_00680 0.0 yerA 3.5.4.2 F adenine deaminase
IEDFAACK_00681 4.9e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
IEDFAACK_00682 4.8e-51 yerC S protein conserved in bacteria
IEDFAACK_00683 2e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
IEDFAACK_00685 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IEDFAACK_00686 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IEDFAACK_00687 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IEDFAACK_00688 3e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
IEDFAACK_00689 6.6e-195 yerI S homoserine kinase type II (protein kinase fold)
IEDFAACK_00690 1.6e-123 sapB S MgtC SapB transporter
IEDFAACK_00691 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEDFAACK_00692 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEDFAACK_00693 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IEDFAACK_00694 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEDFAACK_00695 1.6e-146 yerO K Transcriptional regulator
IEDFAACK_00696 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IEDFAACK_00697 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IEDFAACK_00698 6.4e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEDFAACK_00700 3.9e-47 L nucleic acid phosphodiester bond hydrolysis
IEDFAACK_00701 9.2e-128 L nucleic acid phosphodiester bond hydrolysis
IEDFAACK_00702 9e-165 3.4.24.40 CO amine dehydrogenase activity
IEDFAACK_00703 7.9e-213 S Tetratricopeptide repeat
IEDFAACK_00705 9.4e-127 yeeN K transcriptional regulatory protein
IEDFAACK_00707 8.8e-99 dhaR3 K Transcriptional regulator
IEDFAACK_00708 2.2e-81 yesE S SnoaL-like domain
IEDFAACK_00709 2.9e-89 yesF GM NAD(P)H-binding
IEDFAACK_00710 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
IEDFAACK_00711 1.5e-45 cotJB S CotJB protein
IEDFAACK_00712 5.2e-104 cotJC P Spore Coat
IEDFAACK_00713 6e-102 yesJ K Acetyltransferase (GNAT) family
IEDFAACK_00714 1.8e-102 yesL S Protein of unknown function, DUF624
IEDFAACK_00715 0.0 yesM 2.7.13.3 T Histidine kinase
IEDFAACK_00716 1e-201 yesN K helix_turn_helix, arabinose operon control protein
IEDFAACK_00717 1.6e-246 yesO G Bacterial extracellular solute-binding protein
IEDFAACK_00718 3.1e-170 yesP G Binding-protein-dependent transport system inner membrane component
IEDFAACK_00719 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
IEDFAACK_00720 7.8e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
IEDFAACK_00721 0.0 yesS K Transcriptional regulator
IEDFAACK_00722 2.7e-131 E GDSL-like Lipase/Acylhydrolase
IEDFAACK_00723 3.2e-129 yesU S Domain of unknown function (DUF1961)
IEDFAACK_00724 1e-113 yesV S Protein of unknown function, DUF624
IEDFAACK_00725 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
IEDFAACK_00726 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
IEDFAACK_00727 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
IEDFAACK_00728 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
IEDFAACK_00729 0.0 yetA
IEDFAACK_00730 6.2e-290 lplA G Bacterial extracellular solute-binding protein
IEDFAACK_00731 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
IEDFAACK_00732 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
IEDFAACK_00733 1e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IEDFAACK_00734 6.1e-123 yetF S membrane
IEDFAACK_00735 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IEDFAACK_00736 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEDFAACK_00737 2.2e-34
IEDFAACK_00738 8.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IEDFAACK_00739 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
IEDFAACK_00740 2.6e-104 yetJ S Belongs to the BI1 family
IEDFAACK_00741 2.4e-30 yetM CH FAD binding domain
IEDFAACK_00742 3.6e-199 yetN S Protein of unknown function (DUF3900)
IEDFAACK_00743 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IEDFAACK_00744 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IEDFAACK_00745 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
IEDFAACK_00746 1.9e-172 yfnG 4.2.1.45 M dehydratase
IEDFAACK_00747 5.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
IEDFAACK_00748 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
IEDFAACK_00749 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
IEDFAACK_00750 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
IEDFAACK_00751 2.5e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IEDFAACK_00752 1.4e-240 yfnA E amino acid
IEDFAACK_00753 2.4e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IEDFAACK_00754 1.1e-113 yfmS NT chemotaxis protein
IEDFAACK_00755 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IEDFAACK_00756 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
IEDFAACK_00757 2.4e-69 yfmP K transcriptional
IEDFAACK_00758 9.5e-209 yfmO EGP Major facilitator Superfamily
IEDFAACK_00759 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IEDFAACK_00760 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
IEDFAACK_00761 6.8e-75 yfmK 2.3.1.128 K acetyltransferase
IEDFAACK_00762 6.7e-187 yfmJ S N-terminal domain of oxidoreductase
IEDFAACK_00763 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
IEDFAACK_00764 3.6e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_00765 6.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_00766 1.2e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IEDFAACK_00767 2.6e-24 S Protein of unknown function (DUF3212)
IEDFAACK_00768 7.6e-58 yflT S Heat induced stress protein YflT
IEDFAACK_00769 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
IEDFAACK_00770 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
IEDFAACK_00771 4.1e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IEDFAACK_00772 2.4e-116 citT T response regulator
IEDFAACK_00773 1.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
IEDFAACK_00774 8.5e-227 citM C Citrate transporter
IEDFAACK_00775 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
IEDFAACK_00776 7.4e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IEDFAACK_00777 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IEDFAACK_00778 1.9e-121 yflK S protein conserved in bacteria
IEDFAACK_00779 4e-18 yflJ S Protein of unknown function (DUF2639)
IEDFAACK_00780 4.1e-19 yflI
IEDFAACK_00781 1.5e-49 yflH S Protein of unknown function (DUF3243)
IEDFAACK_00782 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
IEDFAACK_00783 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IEDFAACK_00784 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IEDFAACK_00785 6.6e-66 yhdN S Domain of unknown function (DUF1992)
IEDFAACK_00786 2.2e-252 agcS_1 E Sodium alanine symporter
IEDFAACK_00787 2.2e-25 yfkQ EG Spore germination protein
IEDFAACK_00788 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEDFAACK_00789 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IEDFAACK_00790 6.7e-133 treR K transcriptional
IEDFAACK_00791 1.1e-124 yfkO C nitroreductase
IEDFAACK_00792 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IEDFAACK_00793 4.3e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
IEDFAACK_00794 6.8e-207 ydiM EGP Major facilitator Superfamily
IEDFAACK_00795 1.3e-28 yfkK S Belongs to the UPF0435 family
IEDFAACK_00796 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEDFAACK_00797 8.4e-51 yfkI S gas vesicle protein
IEDFAACK_00798 9.7e-144 yihY S Belongs to the UPF0761 family
IEDFAACK_00800 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
IEDFAACK_00801 6.1e-183 cax P COG0387 Ca2 H antiporter
IEDFAACK_00802 1.2e-146 yfkD S YfkD-like protein
IEDFAACK_00803 6e-149 yfkC M Mechanosensitive ion channel
IEDFAACK_00804 5.4e-222 yfkA S YfkB-like domain
IEDFAACK_00805 1.1e-26 yfjT
IEDFAACK_00806 1.7e-153 pdaA G deacetylase
IEDFAACK_00807 8e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IEDFAACK_00808 1.7e-184 corA P Mediates influx of magnesium ions
IEDFAACK_00809 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IEDFAACK_00810 5.3e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEDFAACK_00811 1.2e-37 S YfzA-like protein
IEDFAACK_00812 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEDFAACK_00813 9.6e-85 yfjM S Psort location Cytoplasmic, score
IEDFAACK_00814 4.3e-28 yfjL
IEDFAACK_00815 1.1e-189 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IEDFAACK_00816 5.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IEDFAACK_00817 1.3e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IEDFAACK_00818 2.8e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IEDFAACK_00819 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
IEDFAACK_00820 1.3e-24 sspH S Belongs to the SspH family
IEDFAACK_00821 4e-56 yfjF S UPF0060 membrane protein
IEDFAACK_00822 6.5e-80 S Family of unknown function (DUF5381)
IEDFAACK_00823 1.8e-101 yfjD S Family of unknown function (DUF5381)
IEDFAACK_00824 1.5e-143 yfjC
IEDFAACK_00825 2e-190 yfjB
IEDFAACK_00826 2.6e-44 yfjA S Belongs to the WXG100 family
IEDFAACK_00827 8.4e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IEDFAACK_00828 2.7e-140 glvR K Helix-turn-helix domain, rpiR family
IEDFAACK_00829 2e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEDFAACK_00830 2.4e-306 yfiB3 V ABC transporter
IEDFAACK_00831 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
IEDFAACK_00832 9.8e-65 mhqP S DoxX
IEDFAACK_00833 5.7e-163 yfiE 1.13.11.2 S glyoxalase
IEDFAACK_00834 1.2e-48 S Oxidoreductase
IEDFAACK_00836 2.6e-211 yxjM T Histidine kinase
IEDFAACK_00837 1e-111 KT LuxR family transcriptional regulator
IEDFAACK_00838 6.6e-165 V ABC transporter, ATP-binding protein
IEDFAACK_00839 8.9e-207 V ABC-2 family transporter protein
IEDFAACK_00840 7.6e-203 V COG0842 ABC-type multidrug transport system, permease component
IEDFAACK_00841 1.8e-93 padR K transcriptional
IEDFAACK_00842 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
IEDFAACK_00843 2.9e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IEDFAACK_00844 1.8e-98 yfiT S Belongs to the metal hydrolase YfiT family
IEDFAACK_00845 1.4e-281 yfiU EGP Major facilitator Superfamily
IEDFAACK_00846 4.9e-79 yfiV K transcriptional
IEDFAACK_00847 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IEDFAACK_00848 5.7e-175 yfiY P ABC transporter substrate-binding protein
IEDFAACK_00849 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_00850 1.3e-169 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_00851 3.9e-167 yfhB 5.3.3.17 S PhzF family
IEDFAACK_00852 8.8e-107 yfhC C nitroreductase
IEDFAACK_00853 2.1e-25 yfhD S YfhD-like protein
IEDFAACK_00855 5.1e-170 yfhF S nucleoside-diphosphate sugar epimerase
IEDFAACK_00856 7.4e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
IEDFAACK_00857 9.7e-52 yfhH S Protein of unknown function (DUF1811)
IEDFAACK_00859 1.1e-209 yfhI EGP Major facilitator Superfamily
IEDFAACK_00860 6.2e-20 sspK S reproduction
IEDFAACK_00861 1.3e-44 yfhJ S WVELL protein
IEDFAACK_00862 5.1e-90 batE T Bacterial SH3 domain homologues
IEDFAACK_00863 3.5e-51 yfhL S SdpI/YhfL protein family
IEDFAACK_00864 2.2e-170 yfhM S Alpha beta hydrolase
IEDFAACK_00865 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IEDFAACK_00866 0.0 yfhO S Bacterial membrane protein YfhO
IEDFAACK_00867 1.2e-185 yfhP S membrane-bound metal-dependent
IEDFAACK_00868 3.3e-210 mutY L A G-specific
IEDFAACK_00869 1.2e-35 yfhS
IEDFAACK_00870 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEDFAACK_00871 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
IEDFAACK_00872 1.5e-37 ygaB S YgaB-like protein
IEDFAACK_00873 1.3e-104 ygaC J Belongs to the UPF0374 family
IEDFAACK_00874 1.8e-301 ygaD V ABC transporter
IEDFAACK_00875 3.3e-179 ygaE S Membrane
IEDFAACK_00876 1.7e-243 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IEDFAACK_00877 2.4e-86 bcp 1.11.1.15 O Peroxiredoxin
IEDFAACK_00878 4e-80 perR P Belongs to the Fur family
IEDFAACK_00879 9.5e-56 ygzB S UPF0295 protein
IEDFAACK_00880 2.5e-166 ygxA S Nucleotidyltransferase-like
IEDFAACK_00881 3.4e-39 S COG NOG14552 non supervised orthologous group
IEDFAACK_00886 7.8e-08
IEDFAACK_00894 2e-08
IEDFAACK_00898 6.5e-142 spo0M S COG4326 Sporulation control protein
IEDFAACK_00899 1.2e-26
IEDFAACK_00900 1.4e-132 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
IEDFAACK_00901 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IEDFAACK_00902 1.1e-261 ygaK C Berberine and berberine like
IEDFAACK_00904 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IEDFAACK_00905 1.5e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IEDFAACK_00906 8.1e-169 ssuA M Sulfonate ABC transporter
IEDFAACK_00907 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IEDFAACK_00908 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
IEDFAACK_00910 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEDFAACK_00911 1.7e-76 ygaO
IEDFAACK_00912 4.4e-29 K Transcriptional regulator
IEDFAACK_00914 2.3e-113 yhzB S B3/4 domain
IEDFAACK_00915 3.5e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IEDFAACK_00916 4.8e-176 yhbB S Putative amidase domain
IEDFAACK_00917 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IEDFAACK_00918 6e-109 yhbD K Protein of unknown function (DUF4004)
IEDFAACK_00919 1.4e-58 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
IEDFAACK_00920 6.1e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
IEDFAACK_00921 0.0 prkA T Ser protein kinase
IEDFAACK_00922 2.5e-225 yhbH S Belongs to the UPF0229 family
IEDFAACK_00923 2.2e-76 yhbI K DNA-binding transcription factor activity
IEDFAACK_00924 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
IEDFAACK_00925 3.1e-271 yhcA EGP Major facilitator Superfamily
IEDFAACK_00926 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
IEDFAACK_00927 2.3e-36 yhcC
IEDFAACK_00928 3.5e-55
IEDFAACK_00929 7.3e-59 yhcF K Transcriptional regulator
IEDFAACK_00930 1.5e-121 yhcG V ABC transporter, ATP-binding protein
IEDFAACK_00931 2.2e-165 yhcH V ABC transporter, ATP-binding protein
IEDFAACK_00932 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IEDFAACK_00933 1e-30 cspB K Cold-shock protein
IEDFAACK_00934 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
IEDFAACK_00935 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
IEDFAACK_00936 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEDFAACK_00937 1.7e-41 yhcM
IEDFAACK_00938 1.7e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IEDFAACK_00939 2.5e-167 yhcP
IEDFAACK_00940 5.2e-100 yhcQ M Spore coat protein
IEDFAACK_00941 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
IEDFAACK_00942 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
IEDFAACK_00943 2.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IEDFAACK_00944 9.3e-68 yhcU S Family of unknown function (DUF5365)
IEDFAACK_00945 9.9e-68 yhcV S COG0517 FOG CBS domain
IEDFAACK_00946 1e-119 yhcW 5.4.2.6 S hydrolase
IEDFAACK_00947 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IEDFAACK_00948 3e-259 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEDFAACK_00949 9.9e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IEDFAACK_00950 5.7e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
IEDFAACK_00951 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IEDFAACK_00952 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IEDFAACK_00953 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IEDFAACK_00954 1.5e-211 yhcY 2.7.13.3 T Histidine kinase
IEDFAACK_00955 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEDFAACK_00956 1.4e-82 azr 1.7.1.6 S NADPH-dependent FMN reductase
IEDFAACK_00957 6.1e-38 yhdB S YhdB-like protein
IEDFAACK_00958 2e-52 yhdC S Protein of unknown function (DUF3889)
IEDFAACK_00959 1.9e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IEDFAACK_00960 1e-75 nsrR K Transcriptional regulator
IEDFAACK_00961 1.3e-237 ygxB M Conserved TM helix
IEDFAACK_00962 3.7e-276 ycgB S Stage V sporulation protein R
IEDFAACK_00963 9.2e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
IEDFAACK_00964 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IEDFAACK_00965 3.8e-162 citR K Transcriptional regulator
IEDFAACK_00966 4.1e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
IEDFAACK_00967 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEDFAACK_00968 3.4e-250 yhdG E amino acid
IEDFAACK_00969 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IEDFAACK_00970 5.1e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEDFAACK_00971 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEDFAACK_00972 8.1e-45 yhdK S Sigma-M inhibitor protein
IEDFAACK_00973 6.6e-201 yhdL S Sigma factor regulator N-terminal
IEDFAACK_00974 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
IEDFAACK_00975 5.9e-191 yhdN C Aldo keto reductase
IEDFAACK_00976 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IEDFAACK_00977 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IEDFAACK_00978 4.7e-74 cueR K transcriptional
IEDFAACK_00979 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
IEDFAACK_00980 1.4e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
IEDFAACK_00981 7.1e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEDFAACK_00982 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEDFAACK_00983 8.9e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IEDFAACK_00985 1.4e-182 yhdY M Mechanosensitive ion channel
IEDFAACK_00986 7.9e-137 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IEDFAACK_00987 6.3e-146 yheN G deacetylase
IEDFAACK_00988 6.9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IEDFAACK_00989 8.6e-230 nhaC C Na H antiporter
IEDFAACK_00990 7.6e-84 nhaX T Belongs to the universal stress protein A family
IEDFAACK_00991 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
IEDFAACK_00992 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
IEDFAACK_00993 2.6e-109 yheG GM NAD(P)H-binding
IEDFAACK_00994 6.3e-28 sspB S spore protein
IEDFAACK_00995 1.3e-36 yheE S Family of unknown function (DUF5342)
IEDFAACK_00996 9.7e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
IEDFAACK_00997 4.3e-216 yheC HJ YheC/D like ATP-grasp
IEDFAACK_00998 2.2e-202 yheB S Belongs to the UPF0754 family
IEDFAACK_00999 9.5e-48 yheA S Belongs to the UPF0342 family
IEDFAACK_01000 3e-201 yhaZ L DNA alkylation repair enzyme
IEDFAACK_01001 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
IEDFAACK_01002 2.5e-291 hemZ H coproporphyrinogen III oxidase
IEDFAACK_01003 1.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
IEDFAACK_01004 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
IEDFAACK_01006 2.7e-130 yhaR 5.3.3.18 I enoyl-CoA hydratase
IEDFAACK_01007 7e-26 S YhzD-like protein
IEDFAACK_01008 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
IEDFAACK_01009 9.4e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
IEDFAACK_01010 2.6e-225 yhaO L DNA repair exonuclease
IEDFAACK_01011 0.0 yhaN L AAA domain
IEDFAACK_01012 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
IEDFAACK_01013 1.6e-21 yhaL S Sporulation protein YhaL
IEDFAACK_01014 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IEDFAACK_01015 1.1e-89 yhaK S Putative zincin peptidase
IEDFAACK_01016 1.3e-54 yhaI S Protein of unknown function (DUF1878)
IEDFAACK_01017 1e-113 hpr K Negative regulator of protease production and sporulation
IEDFAACK_01018 7e-39 yhaH S YtxH-like protein
IEDFAACK_01019 2.4e-21
IEDFAACK_01020 3.6e-80 trpP S Tryptophan transporter TrpP
IEDFAACK_01021 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IEDFAACK_01022 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IEDFAACK_01023 1.8e-136 ecsA V transporter (ATP-binding protein)
IEDFAACK_01024 5e-213 ecsB U ABC transporter
IEDFAACK_01025 3.4e-113 ecsC S EcsC protein family
IEDFAACK_01026 2e-227 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IEDFAACK_01027 3.5e-231 yhfA C membrane
IEDFAACK_01028 1.2e-30 1.15.1.2 C Rubrerythrin
IEDFAACK_01029 7.1e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IEDFAACK_01030 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IEDFAACK_01031 2e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IEDFAACK_01032 2.3e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IEDFAACK_01033 5e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IEDFAACK_01034 5.4e-101 yhgD K Transcriptional regulator
IEDFAACK_01035 1.9e-205 yhgE S YhgE Pip N-terminal domain protein
IEDFAACK_01036 8.7e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEDFAACK_01037 2.2e-137 yhfC S Putative membrane peptidase family (DUF2324)
IEDFAACK_01038 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
IEDFAACK_01039 1.1e-71 3.4.13.21 S ASCH
IEDFAACK_01040 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEDFAACK_01041 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IEDFAACK_01042 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
IEDFAACK_01043 1.4e-110 yhfK GM NmrA-like family
IEDFAACK_01044 5.7e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IEDFAACK_01045 1.3e-64 yhfM
IEDFAACK_01046 1.2e-241 yhfN 3.4.24.84 O Peptidase M48
IEDFAACK_01047 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
IEDFAACK_01048 1.6e-76 VY92_01935 K acetyltransferase
IEDFAACK_01049 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
IEDFAACK_01050 4.3e-159 yfmC M Periplasmic binding protein
IEDFAACK_01051 5.5e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IEDFAACK_01052 3.2e-195 vraB 2.3.1.9 I Belongs to the thiolase family
IEDFAACK_01053 5.6e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IEDFAACK_01054 1.9e-90 bioY S BioY family
IEDFAACK_01055 3.1e-181 hemAT NT chemotaxis protein
IEDFAACK_01056 8e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
IEDFAACK_01057 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEDFAACK_01058 1.3e-32 yhzC S IDEAL
IEDFAACK_01059 4.2e-109 comK K Competence transcription factor
IEDFAACK_01060 1.4e-167 IQ Enoyl-(Acyl carrier protein) reductase
IEDFAACK_01061 3.9e-41 yhjA S Excalibur calcium-binding domain
IEDFAACK_01062 2e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEDFAACK_01063 6.9e-27 yhjC S Protein of unknown function (DUF3311)
IEDFAACK_01064 6.7e-60 yhjD
IEDFAACK_01065 5.9e-109 yhjE S SNARE associated Golgi protein
IEDFAACK_01066 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
IEDFAACK_01067 4.5e-280 yhjG CH FAD binding domain
IEDFAACK_01068 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
IEDFAACK_01069 1.3e-213 glcP G Major Facilitator Superfamily
IEDFAACK_01070 5.5e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
IEDFAACK_01071 7.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
IEDFAACK_01072 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
IEDFAACK_01073 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
IEDFAACK_01074 4.2e-201 abrB S membrane
IEDFAACK_01075 4.5e-198 EGP Transmembrane secretion effector
IEDFAACK_01076 2.1e-117 S Sugar transport-related sRNA regulator N-term
IEDFAACK_01077 3.7e-204 S Sugar transport-related sRNA regulator N-term
IEDFAACK_01078 2.2e-78 yhjR S Rubrerythrin
IEDFAACK_01079 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
IEDFAACK_01080 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IEDFAACK_01081 4.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IEDFAACK_01082 0.0 sbcC L COG0419 ATPase involved in DNA repair
IEDFAACK_01083 2.5e-49 yisB V COG1403 Restriction endonuclease
IEDFAACK_01084 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
IEDFAACK_01085 5.3e-63 gerPE S Spore germination protein GerPE
IEDFAACK_01086 1.1e-23 gerPD S Spore germination protein
IEDFAACK_01087 5.3e-54 gerPC S Spore germination protein
IEDFAACK_01088 1.2e-33 gerPB S cell differentiation
IEDFAACK_01089 1.9e-33 gerPA S Spore germination protein
IEDFAACK_01090 1.5e-22 yisI S Spo0E like sporulation regulatory protein
IEDFAACK_01091 1.1e-172 cotH M Spore Coat
IEDFAACK_01092 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IEDFAACK_01093 3e-57 yisL S UPF0344 protein
IEDFAACK_01094 0.0 wprA O Belongs to the peptidase S8 family
IEDFAACK_01095 9.7e-103 yisN S Protein of unknown function (DUF2777)
IEDFAACK_01096 0.0 asnO 6.3.5.4 E Asparagine synthase
IEDFAACK_01097 1.1e-41 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
IEDFAACK_01098 4e-243 yisQ V Mate efflux family protein
IEDFAACK_01099 3.5e-160 yisR K Transcriptional regulator
IEDFAACK_01100 2e-183 purR K helix_turn _helix lactose operon repressor
IEDFAACK_01101 2.3e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
IEDFAACK_01102 1.8e-92 yisT S DinB family
IEDFAACK_01103 6e-106 argO S Lysine exporter protein LysE YggA
IEDFAACK_01104 5.6e-272 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEDFAACK_01105 1.2e-35 mcbG S Pentapeptide repeats (9 copies)
IEDFAACK_01106 5.9e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IEDFAACK_01107 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
IEDFAACK_01108 3.3e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
IEDFAACK_01109 1.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
IEDFAACK_01110 1.2e-118 comB 3.1.3.71 H Belongs to the ComB family
IEDFAACK_01111 3.5e-140 yitD 4.4.1.19 S synthase
IEDFAACK_01112 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEDFAACK_01113 3.5e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IEDFAACK_01114 1.3e-227 yitG EGP Major facilitator Superfamily
IEDFAACK_01115 7.9e-157 yitH K Acetyltransferase (GNAT) domain
IEDFAACK_01116 4.2e-43 yjcF S Acetyltransferase (GNAT) domain
IEDFAACK_01117 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IEDFAACK_01118 8.6e-55 yajQ S Belongs to the UPF0234 family
IEDFAACK_01119 3.4e-160 cvfB S protein conserved in bacteria
IEDFAACK_01120 8.5e-94
IEDFAACK_01121 8.9e-170
IEDFAACK_01122 1.5e-97 S Sporulation delaying protein SdpA
IEDFAACK_01123 1.5e-58 K Transcriptional regulator PadR-like family
IEDFAACK_01124 1.3e-94
IEDFAACK_01125 1.4e-44 yitR S Domain of unknown function (DUF3784)
IEDFAACK_01126 3.9e-306 nprB 3.4.24.28 E Peptidase M4
IEDFAACK_01127 9.3e-158 yitS S protein conserved in bacteria
IEDFAACK_01128 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
IEDFAACK_01129 5e-73 ipi S Intracellular proteinase inhibitor
IEDFAACK_01130 1.2e-17 S Protein of unknown function (DUF3813)
IEDFAACK_01132 5.4e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IEDFAACK_01133 1.7e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IEDFAACK_01134 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
IEDFAACK_01135 1.5e-22 pilT S Proteolipid membrane potential modulator
IEDFAACK_01136 1.7e-268 yitY C D-arabinono-1,4-lactone oxidase
IEDFAACK_01137 1.7e-88 norB G Major Facilitator Superfamily
IEDFAACK_01138 3.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IEDFAACK_01139 2.2e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IEDFAACK_01140 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IEDFAACK_01141 3.2e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IEDFAACK_01142 1.4e-203 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IEDFAACK_01143 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
IEDFAACK_01144 3.3e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IEDFAACK_01145 9.5e-28 yjzC S YjzC-like protein
IEDFAACK_01146 2.3e-16 yjzD S Protein of unknown function (DUF2929)
IEDFAACK_01147 3.1e-141 yjaU I carboxylic ester hydrolase activity
IEDFAACK_01148 6.9e-101 yjaV
IEDFAACK_01149 2.5e-183 med S Transcriptional activator protein med
IEDFAACK_01150 7.3e-26 comZ S ComZ
IEDFAACK_01151 3.9e-10 yjzB
IEDFAACK_01152 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEDFAACK_01153 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IEDFAACK_01154 2.5e-149 yjaZ O Zn-dependent protease
IEDFAACK_01155 1.8e-184 appD P Belongs to the ABC transporter superfamily
IEDFAACK_01156 4.2e-186 appF E Belongs to the ABC transporter superfamily
IEDFAACK_01157 3.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
IEDFAACK_01158 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEDFAACK_01159 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEDFAACK_01160 5e-147 yjbA S Belongs to the UPF0736 family
IEDFAACK_01161 4e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IEDFAACK_01162 0.0 oppA E ABC transporter substrate-binding protein
IEDFAACK_01163 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEDFAACK_01164 1e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEDFAACK_01165 1.5e-197 oppD P Belongs to the ABC transporter superfamily
IEDFAACK_01166 5.5e-172 oppF E Belongs to the ABC transporter superfamily
IEDFAACK_01167 5.3e-210 yjbB EGP Major Facilitator Superfamily
IEDFAACK_01168 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEDFAACK_01169 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IEDFAACK_01170 2.3e-111 yjbE P Integral membrane protein TerC family
IEDFAACK_01171 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IEDFAACK_01172 4.4e-219 yjbF S Competence protein
IEDFAACK_01173 0.0 pepF E oligoendopeptidase F
IEDFAACK_01174 1.8e-20
IEDFAACK_01175 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IEDFAACK_01176 3.7e-72 yjbI S Bacterial-like globin
IEDFAACK_01177 5.1e-88 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IEDFAACK_01178 4.1e-101 yjbK S protein conserved in bacteria
IEDFAACK_01179 2.7e-61 yjbL S Belongs to the UPF0738 family
IEDFAACK_01180 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
IEDFAACK_01181 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEDFAACK_01182 6.8e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IEDFAACK_01183 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IEDFAACK_01184 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IEDFAACK_01185 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IEDFAACK_01186 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
IEDFAACK_01187 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
IEDFAACK_01188 6.7e-30 thiS H thiamine diphosphate biosynthetic process
IEDFAACK_01189 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IEDFAACK_01190 8.1e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IEDFAACK_01191 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IEDFAACK_01192 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IEDFAACK_01193 1.4e-52 yjbX S Spore coat protein
IEDFAACK_01194 5.2e-83 cotZ S Spore coat protein
IEDFAACK_01195 3.4e-96 cotY S Spore coat protein Z
IEDFAACK_01196 6.4e-77 cotX S Spore Coat Protein X and V domain
IEDFAACK_01197 8.5e-32 cotW
IEDFAACK_01198 2.3e-55 cotV S Spore Coat Protein X and V domain
IEDFAACK_01199 4.3e-56 yjcA S Protein of unknown function (DUF1360)
IEDFAACK_01202 2.9e-38 spoVIF S Stage VI sporulation protein F
IEDFAACK_01203 0.0 yjcD 3.6.4.12 L DNA helicase
IEDFAACK_01204 1.7e-38
IEDFAACK_01205 1.1e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEDFAACK_01206 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
IEDFAACK_01207 3.2e-135 yjcH P COG2382 Enterochelin esterase and related enzymes
IEDFAACK_01208 7.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IEDFAACK_01209 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IEDFAACK_01210 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
IEDFAACK_01211 9.5e-209 yjcL S Protein of unknown function (DUF819)
IEDFAACK_01213 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
IEDFAACK_01214 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
IEDFAACK_01216 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
IEDFAACK_01217 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
IEDFAACK_01218 3.1e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
IEDFAACK_01219 3e-45 yjdF S Protein of unknown function (DUF2992)
IEDFAACK_01220 3.4e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
IEDFAACK_01222 2.2e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IEDFAACK_01223 7.1e-29 S Domain of unknown function (DUF4177)
IEDFAACK_01224 1.5e-50 yjdJ S Domain of unknown function (DUF4306)
IEDFAACK_01225 1.6e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IEDFAACK_01227 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
IEDFAACK_01228 5.5e-77 S Protein of unknown function (DUF2690)
IEDFAACK_01229 2.3e-20 yjfB S Putative motility protein
IEDFAACK_01230 2.1e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
IEDFAACK_01231 4.9e-34 T PhoQ Sensor
IEDFAACK_01232 1.7e-102 yjgB S Domain of unknown function (DUF4309)
IEDFAACK_01233 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
IEDFAACK_01234 3.7e-94 yjgD S Protein of unknown function (DUF1641)
IEDFAACK_01236 2.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
IEDFAACK_01238 8.9e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
IEDFAACK_01239 1.1e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IEDFAACK_01240 8.2e-30
IEDFAACK_01241 7.3e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IEDFAACK_01242 1.9e-122 ybbM S transport system, permease component
IEDFAACK_01243 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
IEDFAACK_01244 3.9e-28 yjlA EG Putative multidrug resistance efflux transporter
IEDFAACK_01245 3.4e-91 yjlB S Cupin domain
IEDFAACK_01246 7.1e-66 yjlC S Protein of unknown function (DUF1641)
IEDFAACK_01247 8.5e-218 yjlD 1.6.99.3 C NADH dehydrogenase
IEDFAACK_01248 3.3e-277 uxaC 5.3.1.12 G glucuronate isomerase
IEDFAACK_01249 1.6e-247 yjmB G symporter YjmB
IEDFAACK_01250 1.6e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IEDFAACK_01251 1.3e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
IEDFAACK_01252 1.1e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
IEDFAACK_01253 5.2e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFAACK_01254 4.1e-226 exuT G Sugar (and other) transporter
IEDFAACK_01255 6.8e-184 exuR K transcriptional
IEDFAACK_01256 9.2e-283 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
IEDFAACK_01257 2.5e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
IEDFAACK_01258 7.4e-130 MA20_18170 S membrane transporter protein
IEDFAACK_01259 2.3e-78 yjoA S DinB family
IEDFAACK_01260 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
IEDFAACK_01261 1e-212 S response regulator aspartate phosphatase
IEDFAACK_01263 1.6e-39 S YCII-related domain
IEDFAACK_01264 1.6e-161 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
IEDFAACK_01265 6.1e-61 yjqA S Bacterial PH domain
IEDFAACK_01266 7.9e-111 yjqB S Pfam:DUF867
IEDFAACK_01267 4.4e-160 ydbD P Catalase
IEDFAACK_01268 1e-110 xkdA E IrrE N-terminal-like domain
IEDFAACK_01269 9.2e-56 xre K Helix-turn-helix XRE-family like proteins
IEDFAACK_01271 5e-156 xkdB K sequence-specific DNA binding
IEDFAACK_01272 9.2e-118 xkdC L Bacterial dnaA protein
IEDFAACK_01275 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
IEDFAACK_01276 4.5e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IEDFAACK_01277 5.3e-139 xtmA L phage terminase small subunit
IEDFAACK_01278 1.4e-253 xtmB S phage terminase, large subunit
IEDFAACK_01279 4.6e-285 yqbA S portal protein
IEDFAACK_01280 7.7e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
IEDFAACK_01281 1.7e-168 xkdG S Phage capsid family
IEDFAACK_01282 3.3e-62 yqbG S Protein of unknown function (DUF3199)
IEDFAACK_01283 7.3e-64 yqbH S Domain of unknown function (DUF3599)
IEDFAACK_01284 1.1e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
IEDFAACK_01285 9.3e-77 xkdJ
IEDFAACK_01286 2.5e-256 xkdK S Phage tail sheath C-terminal domain
IEDFAACK_01287 1e-75 xkdM S Phage tail tube protein
IEDFAACK_01288 1.8e-126 xkdO L Transglycosylase SLT domain
IEDFAACK_01289 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
IEDFAACK_01290 2.1e-39 xkdR S Protein of unknown function (DUF2577)
IEDFAACK_01291 9.6e-71 xkdS S Protein of unknown function (DUF2634)
IEDFAACK_01292 3e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IEDFAACK_01293 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
IEDFAACK_01294 8.7e-41
IEDFAACK_01295 7.7e-36
IEDFAACK_01296 3e-33 xkdW S XkdW protein
IEDFAACK_01297 2.1e-21 xkdX
IEDFAACK_01298 2.8e-154 xepA
IEDFAACK_01299 2.8e-39 xhlA S Haemolysin XhlA
IEDFAACK_01300 9.3e-40 xhlB S SPP1 phage holin
IEDFAACK_01301 1.3e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IEDFAACK_01302 6.7e-23 spoIISB S Stage II sporulation protein SB
IEDFAACK_01303 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
IEDFAACK_01304 5.8e-175 pit P phosphate transporter
IEDFAACK_01305 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
IEDFAACK_01306 6.1e-241 steT E amino acid
IEDFAACK_01307 6.1e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
IEDFAACK_01308 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IEDFAACK_01309 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IEDFAACK_01310 1.6e-212 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEDFAACK_01311 9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
IEDFAACK_01312 5.1e-153 dppA E D-aminopeptidase
IEDFAACK_01313 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEDFAACK_01314 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEDFAACK_01315 1e-187 dppD P Belongs to the ABC transporter superfamily
IEDFAACK_01316 0.0 dppE E ABC transporter substrate-binding protein
IEDFAACK_01318 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IEDFAACK_01319 9.8e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IEDFAACK_01320 1e-167 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IEDFAACK_01321 2.6e-183 ykfD E Belongs to the ABC transporter superfamily
IEDFAACK_01322 1.4e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
IEDFAACK_01323 9.4e-158 ykgA E Amidinotransferase
IEDFAACK_01324 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
IEDFAACK_01325 2.8e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEDFAACK_01326 1.5e-09
IEDFAACK_01327 3.9e-128 ykjA S Protein of unknown function (DUF421)
IEDFAACK_01328 2.6e-97 ykkA S Protein of unknown function (DUF664)
IEDFAACK_01329 9.9e-94 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IEDFAACK_01330 1.1e-53 ykkC P Multidrug resistance protein
IEDFAACK_01331 9.1e-50 ykkD P Multidrug resistance protein
IEDFAACK_01332 5.6e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IEDFAACK_01333 7.4e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IEDFAACK_01334 4.5e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IEDFAACK_01335 4.8e-70 ohrA O Organic hydroperoxide resistance protein
IEDFAACK_01336 4.4e-74 ohrR K COG1846 Transcriptional regulators
IEDFAACK_01337 8.4e-72 ohrB O Organic hydroperoxide resistance protein
IEDFAACK_01339 1.4e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
IEDFAACK_01340 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IEDFAACK_01341 5.5e-175 isp O Belongs to the peptidase S8 family
IEDFAACK_01342 2.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IEDFAACK_01343 4.5e-135 ykoC P Cobalt transport protein
IEDFAACK_01344 1.2e-305 P ABC transporter, ATP-binding protein
IEDFAACK_01345 2.6e-98 ykoE S ABC-type cobalt transport system, permease component
IEDFAACK_01346 1.8e-110 ykoF S YKOF-related Family
IEDFAACK_01347 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_01348 2.4e-240 ykoH 2.7.13.3 T Histidine kinase
IEDFAACK_01349 1.2e-110 ykoI S Peptidase propeptide and YPEB domain
IEDFAACK_01350 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
IEDFAACK_01353 2.2e-222 mgtE P Acts as a magnesium transporter
IEDFAACK_01354 1.4e-53 tnrA K transcriptional
IEDFAACK_01355 5.9e-18
IEDFAACK_01356 6.9e-26 ykoL
IEDFAACK_01357 1.3e-81 mhqR K transcriptional
IEDFAACK_01358 9.3e-33 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IEDFAACK_01359 1.2e-165 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IEDFAACK_01360 3.7e-99 ykoP G polysaccharide deacetylase
IEDFAACK_01361 1e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
IEDFAACK_01362 0.0 ykoS
IEDFAACK_01363 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IEDFAACK_01364 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
IEDFAACK_01365 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IEDFAACK_01366 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
IEDFAACK_01367 5.4e-110 ykoX S membrane-associated protein
IEDFAACK_01368 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IEDFAACK_01369 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEDFAACK_01370 6.7e-111 rsgI S Anti-sigma factor N-terminus
IEDFAACK_01371 1.9e-26 sspD S small acid-soluble spore protein
IEDFAACK_01372 1.5e-124 ykrK S Domain of unknown function (DUF1836)
IEDFAACK_01373 1.7e-154 htpX O Belongs to the peptidase M48B family
IEDFAACK_01374 6.3e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
IEDFAACK_01375 1.2e-10 ydfR S Protein of unknown function (DUF421)
IEDFAACK_01376 3.5e-20 ykzE
IEDFAACK_01377 3.2e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
IEDFAACK_01378 0.0 kinE 2.7.13.3 T Histidine kinase
IEDFAACK_01379 5.9e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEDFAACK_01381 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IEDFAACK_01382 3.7e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IEDFAACK_01383 1.7e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IEDFAACK_01384 5.2e-231 mtnE 2.6.1.83 E Aminotransferase
IEDFAACK_01385 1.2e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IEDFAACK_01386 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IEDFAACK_01387 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IEDFAACK_01388 5.4e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IEDFAACK_01389 1.1e-50 XK27_09985 S Protein of unknown function (DUF1232)
IEDFAACK_01390 7.5e-10 S Spo0E like sporulation regulatory protein
IEDFAACK_01391 1.8e-64 eag
IEDFAACK_01392 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
IEDFAACK_01393 1.3e-75 ykvE K transcriptional
IEDFAACK_01394 2.5e-125 motB N Flagellar motor protein
IEDFAACK_01395 1e-137 motA N flagellar motor
IEDFAACK_01396 0.0 clpE O Belongs to the ClpA ClpB family
IEDFAACK_01397 3.3e-181 ykvI S membrane
IEDFAACK_01398 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IEDFAACK_01399 1.8e-80 queD 4.1.2.50, 4.2.3.12 H synthase
IEDFAACK_01400 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IEDFAACK_01401 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IEDFAACK_01402 2.2e-60 ykvN K HxlR-like helix-turn-helix
IEDFAACK_01403 7e-133 IQ Enoyl-(Acyl carrier protein) reductase
IEDFAACK_01404 1.2e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
IEDFAACK_01405 3.5e-35 3.5.1.104 M LysM domain
IEDFAACK_01406 4e-130 G Glycosyl hydrolases family 18
IEDFAACK_01408 5.6e-46 ykvR S Protein of unknown function (DUF3219)
IEDFAACK_01409 6e-25 ykvS S protein conserved in bacteria
IEDFAACK_01410 2.8e-28
IEDFAACK_01411 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
IEDFAACK_01412 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEDFAACK_01413 4.9e-90 stoA CO thiol-disulfide
IEDFAACK_01414 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IEDFAACK_01415 2.3e-09
IEDFAACK_01416 2.5e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IEDFAACK_01417 4.9e-179 ykvZ 5.1.1.1 K Transcriptional regulator
IEDFAACK_01419 7.6e-128 glcT K antiterminator
IEDFAACK_01420 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEDFAACK_01421 2.1e-39 ptsH G phosphocarrier protein HPr
IEDFAACK_01422 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IEDFAACK_01423 7.2e-39 splA S Transcriptional regulator
IEDFAACK_01424 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
IEDFAACK_01425 2.7e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEDFAACK_01426 1.3e-255 mcpC NT chemotaxis protein
IEDFAACK_01427 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IEDFAACK_01428 1.8e-123 ykwD J protein with SCP PR1 domains
IEDFAACK_01429 6.1e-247 mrdA 3.4.16.4 M Penicillin-binding Protein
IEDFAACK_01430 6.7e-44 mrdA 3.4.16.4 M Penicillin-binding Protein
IEDFAACK_01431 0.0 pilS 2.7.13.3 T Histidine kinase
IEDFAACK_01432 6.3e-221 patA 2.6.1.1 E Aminotransferase
IEDFAACK_01433 2.2e-15
IEDFAACK_01434 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
IEDFAACK_01435 4.9e-84 ykyB S YkyB-like protein
IEDFAACK_01436 2.8e-238 ykuC EGP Major facilitator Superfamily
IEDFAACK_01437 1.8e-87 ykuD S protein conserved in bacteria
IEDFAACK_01438 4.7e-165 ykuE S Metallophosphoesterase
IEDFAACK_01439 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEDFAACK_01440 5.2e-234 ykuI T Diguanylate phosphodiesterase
IEDFAACK_01441 3.9e-37 ykuJ S protein conserved in bacteria
IEDFAACK_01442 4.4e-94 ykuK S Ribonuclease H-like
IEDFAACK_01443 3.9e-27 ykzF S Antirepressor AbbA
IEDFAACK_01444 1.6e-76 ykuL S CBS domain
IEDFAACK_01445 3.5e-168 ccpC K Transcriptional regulator
IEDFAACK_01446 2.9e-84 fld C Flavodoxin domain
IEDFAACK_01447 8.8e-175 ykuO
IEDFAACK_01448 4.3e-77 fld C Flavodoxin
IEDFAACK_01449 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IEDFAACK_01450 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IEDFAACK_01451 9e-37 ykuS S Belongs to the UPF0180 family
IEDFAACK_01452 8.8e-142 ykuT M Mechanosensitive ion channel
IEDFAACK_01453 3.9e-101 ykuU O Alkyl hydroperoxide reductase
IEDFAACK_01454 1.4e-80 ykuV CO thiol-disulfide
IEDFAACK_01455 5.8e-95 rok K Repressor of ComK
IEDFAACK_01456 4.2e-146 yknT
IEDFAACK_01457 1.1e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IEDFAACK_01458 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IEDFAACK_01459 2.6e-244 moeA 2.10.1.1 H molybdopterin
IEDFAACK_01460 2.1e-91 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IEDFAACK_01461 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
IEDFAACK_01462 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IEDFAACK_01463 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
IEDFAACK_01464 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
IEDFAACK_01465 3.6e-115 yknW S Yip1 domain
IEDFAACK_01466 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEDFAACK_01467 9.4e-124 macB V ABC transporter, ATP-binding protein
IEDFAACK_01468 4.7e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
IEDFAACK_01469 3.1e-136 fruR K Transcriptional regulator
IEDFAACK_01470 5.3e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
IEDFAACK_01471 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IEDFAACK_01472 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IEDFAACK_01473 8.1e-39 ykoA
IEDFAACK_01474 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IEDFAACK_01475 2.6e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IEDFAACK_01476 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IEDFAACK_01477 1.1e-12 S Uncharacterized protein YkpC
IEDFAACK_01478 1.7e-182 mreB D Rod-share determining protein MreBH
IEDFAACK_01479 1.5e-43 abrB K of stationary sporulation gene expression
IEDFAACK_01480 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
IEDFAACK_01481 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
IEDFAACK_01482 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
IEDFAACK_01483 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IEDFAACK_01484 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEDFAACK_01485 8.2e-31 ykzG S Belongs to the UPF0356 family
IEDFAACK_01486 5.5e-147 ykrA S hydrolases of the HAD superfamily
IEDFAACK_01487 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IEDFAACK_01489 6.1e-93 recN L Putative cell-wall binding lipoprotein
IEDFAACK_01490 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IEDFAACK_01491 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IEDFAACK_01492 6.6e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IEDFAACK_01493 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IEDFAACK_01494 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
IEDFAACK_01495 1e-276 speA 4.1.1.19 E Arginine
IEDFAACK_01496 1e-41 yktA S Belongs to the UPF0223 family
IEDFAACK_01497 2.1e-117 yktB S Belongs to the UPF0637 family
IEDFAACK_01498 7.1e-26 ykzI
IEDFAACK_01499 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
IEDFAACK_01500 2e-77 ykzC S Acetyltransferase (GNAT) family
IEDFAACK_01501 2.7e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IEDFAACK_01502 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
IEDFAACK_01503 0.0 ylaA
IEDFAACK_01504 3e-41 ylaB
IEDFAACK_01505 2.8e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
IEDFAACK_01506 9.1e-12 sigC S Putative zinc-finger
IEDFAACK_01507 5.9e-37 ylaE
IEDFAACK_01508 8.2e-22 S Family of unknown function (DUF5325)
IEDFAACK_01509 0.0 typA T GTP-binding protein TypA
IEDFAACK_01510 4.2e-47 ylaH S YlaH-like protein
IEDFAACK_01511 2.5e-32 ylaI S protein conserved in bacteria
IEDFAACK_01512 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IEDFAACK_01513 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
IEDFAACK_01514 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IEDFAACK_01515 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
IEDFAACK_01516 8.7e-44 ylaN S Belongs to the UPF0358 family
IEDFAACK_01517 2.7e-211 ftsW D Belongs to the SEDS family
IEDFAACK_01518 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IEDFAACK_01519 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IEDFAACK_01520 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IEDFAACK_01521 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IEDFAACK_01522 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IEDFAACK_01523 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IEDFAACK_01524 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IEDFAACK_01525 8.8e-167 ctaG S cytochrome c oxidase
IEDFAACK_01526 7e-62 ylbA S YugN-like family
IEDFAACK_01527 2.6e-74 ylbB T COG0517 FOG CBS domain
IEDFAACK_01528 2.8e-199 ylbC S protein with SCP PR1 domains
IEDFAACK_01529 4.5e-62 ylbD S Putative coat protein
IEDFAACK_01530 6.7e-37 ylbE S YlbE-like protein
IEDFAACK_01531 1.8e-75 ylbF S Belongs to the UPF0342 family
IEDFAACK_01532 3.7e-38 ylbG S UPF0298 protein
IEDFAACK_01533 2.1e-97 rsmD 2.1.1.171 L Methyltransferase
IEDFAACK_01534 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IEDFAACK_01535 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
IEDFAACK_01536 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
IEDFAACK_01537 7.5e-186 ylbL T Belongs to the peptidase S16 family
IEDFAACK_01538 2.3e-229 ylbM S Belongs to the UPF0348 family
IEDFAACK_01540 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
IEDFAACK_01541 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IEDFAACK_01542 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IEDFAACK_01543 4e-89 ylbP K n-acetyltransferase
IEDFAACK_01544 4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IEDFAACK_01545 2.1e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IEDFAACK_01546 4.2e-77 mraZ K Belongs to the MraZ family
IEDFAACK_01547 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IEDFAACK_01548 3.7e-44 ftsL D Essential cell division protein
IEDFAACK_01549 1.8e-190 ftsI 3.4.16.4 M Penicillin-binding Protein
IEDFAACK_01550 1.4e-94 ftsI 3.4.16.4 M Penicillin-binding Protein
IEDFAACK_01551 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
IEDFAACK_01552 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IEDFAACK_01553 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IEDFAACK_01554 4.5e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IEDFAACK_01555 9.8e-186 spoVE D Belongs to the SEDS family
IEDFAACK_01556 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IEDFAACK_01557 5.3e-167 murB 1.3.1.98 M cell wall formation
IEDFAACK_01558 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IEDFAACK_01559 2.4e-103 ylxW S protein conserved in bacteria
IEDFAACK_01560 1e-102 ylxX S protein conserved in bacteria
IEDFAACK_01561 6.2e-58 sbp S small basic protein
IEDFAACK_01562 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IEDFAACK_01563 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IEDFAACK_01564 0.0 bpr O COG1404 Subtilisin-like serine proteases
IEDFAACK_01565 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IEDFAACK_01566 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEDFAACK_01567 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEDFAACK_01568 1.2e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IEDFAACK_01569 7.5e-252 argE 3.5.1.16 E Acetylornithine deacetylase
IEDFAACK_01570 2.4e-37 ylmC S sporulation protein
IEDFAACK_01571 9.2e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
IEDFAACK_01572 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IEDFAACK_01573 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IEDFAACK_01574 1.3e-39 yggT S membrane
IEDFAACK_01575 3.3e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
IEDFAACK_01576 2.6e-67 divIVA D Cell division initiation protein
IEDFAACK_01577 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IEDFAACK_01578 1.3e-63 dksA T COG1734 DnaK suppressor protein
IEDFAACK_01579 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IEDFAACK_01580 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IEDFAACK_01581 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IEDFAACK_01582 7.6e-231 pyrP F Xanthine uracil
IEDFAACK_01583 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IEDFAACK_01584 2e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IEDFAACK_01585 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IEDFAACK_01586 0.0 carB 6.3.5.5 F Belongs to the CarB family
IEDFAACK_01587 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IEDFAACK_01588 5.4e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IEDFAACK_01589 3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IEDFAACK_01590 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IEDFAACK_01592 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
IEDFAACK_01593 9.2e-179 cysP P phosphate transporter
IEDFAACK_01594 4.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
IEDFAACK_01595 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
IEDFAACK_01596 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IEDFAACK_01597 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
IEDFAACK_01598 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
IEDFAACK_01599 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IEDFAACK_01600 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
IEDFAACK_01601 2.4e-156 yloC S stress-induced protein
IEDFAACK_01602 1.5e-40 ylzA S Belongs to the UPF0296 family
IEDFAACK_01603 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IEDFAACK_01604 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IEDFAACK_01605 2.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IEDFAACK_01606 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEDFAACK_01607 7.3e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IEDFAACK_01608 5.5e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IEDFAACK_01609 4.6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IEDFAACK_01610 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IEDFAACK_01611 1.6e-140 stp 3.1.3.16 T phosphatase
IEDFAACK_01612 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IEDFAACK_01613 7.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IEDFAACK_01614 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IEDFAACK_01615 1.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
IEDFAACK_01616 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IEDFAACK_01617 5.5e-59 asp S protein conserved in bacteria
IEDFAACK_01618 1.7e-301 yloV S kinase related to dihydroxyacetone kinase
IEDFAACK_01619 5.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
IEDFAACK_01620 1.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
IEDFAACK_01621 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IEDFAACK_01622 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IEDFAACK_01623 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IEDFAACK_01624 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IEDFAACK_01625 1.4e-128 IQ reductase
IEDFAACK_01626 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEDFAACK_01627 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IEDFAACK_01628 0.0 smc D Required for chromosome condensation and partitioning
IEDFAACK_01629 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IEDFAACK_01630 2.9e-87
IEDFAACK_01631 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IEDFAACK_01632 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IEDFAACK_01633 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IEDFAACK_01634 4.5e-36 ylqC S Belongs to the UPF0109 family
IEDFAACK_01635 1.4e-60 ylqD S YlqD protein
IEDFAACK_01636 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IEDFAACK_01637 4.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IEDFAACK_01638 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IEDFAACK_01639 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IEDFAACK_01640 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEDFAACK_01641 1.5e-284 ylqG
IEDFAACK_01642 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
IEDFAACK_01643 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IEDFAACK_01644 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IEDFAACK_01645 4e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
IEDFAACK_01646 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IEDFAACK_01647 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IEDFAACK_01648 5.7e-169 xerC L tyrosine recombinase XerC
IEDFAACK_01649 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IEDFAACK_01650 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IEDFAACK_01651 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IEDFAACK_01652 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IEDFAACK_01653 2e-74 flgC N Belongs to the flagella basal body rod proteins family
IEDFAACK_01654 1.9e-31 fliE N Flagellar hook-basal body
IEDFAACK_01655 3.5e-254 fliF N The M ring may be actively involved in energy transduction
IEDFAACK_01656 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IEDFAACK_01657 5.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
IEDFAACK_01658 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IEDFAACK_01659 1.5e-69 fliJ N Flagellar biosynthesis chaperone
IEDFAACK_01660 7.7e-37 ylxF S MgtE intracellular N domain
IEDFAACK_01661 7.1e-214 fliK N Flagellar hook-length control protein
IEDFAACK_01662 2.3e-72 flgD N Flagellar basal body rod modification protein
IEDFAACK_01663 1.9e-136 flgG N Flagellar basal body rod
IEDFAACK_01664 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
IEDFAACK_01665 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IEDFAACK_01666 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IEDFAACK_01667 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
IEDFAACK_01668 1.3e-95 fliZ N Flagellar biosynthesis protein, FliO
IEDFAACK_01669 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
IEDFAACK_01670 2.2e-36 fliQ N Role in flagellar biosynthesis
IEDFAACK_01671 3.6e-132 fliR N Flagellar biosynthetic protein FliR
IEDFAACK_01672 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IEDFAACK_01673 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IEDFAACK_01674 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
IEDFAACK_01675 1.7e-157 flhG D Belongs to the ParA family
IEDFAACK_01676 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IEDFAACK_01677 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
IEDFAACK_01678 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
IEDFAACK_01679 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IEDFAACK_01680 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IEDFAACK_01681 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEDFAACK_01682 5.3e-76 ylxL
IEDFAACK_01683 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
IEDFAACK_01684 2.4e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IEDFAACK_01685 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IEDFAACK_01686 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IEDFAACK_01687 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IEDFAACK_01688 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
IEDFAACK_01689 1.3e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IEDFAACK_01690 1.7e-232 rasP M zinc metalloprotease
IEDFAACK_01691 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IEDFAACK_01692 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEDFAACK_01693 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
IEDFAACK_01694 1.1e-203 nusA K Participates in both transcription termination and antitermination
IEDFAACK_01695 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
IEDFAACK_01696 3.1e-47 ylxQ J ribosomal protein
IEDFAACK_01697 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IEDFAACK_01698 3e-44 ylxP S protein conserved in bacteria
IEDFAACK_01699 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IEDFAACK_01700 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IEDFAACK_01701 4.3e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IEDFAACK_01702 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IEDFAACK_01703 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IEDFAACK_01704 3.6e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
IEDFAACK_01705 4.4e-233 pepR S Belongs to the peptidase M16 family
IEDFAACK_01706 2.6e-42 ymxH S YlmC YmxH family
IEDFAACK_01707 1.9e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
IEDFAACK_01708 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IEDFAACK_01709 1.9e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IEDFAACK_01710 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IEDFAACK_01711 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEDFAACK_01712 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEDFAACK_01713 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
IEDFAACK_01714 4.4e-32 S YlzJ-like protein
IEDFAACK_01715 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IEDFAACK_01716 1.4e-133 ymfC K Transcriptional regulator
IEDFAACK_01717 3.8e-205 ymfD EGP Major facilitator Superfamily
IEDFAACK_01718 1.6e-233 ymfF S Peptidase M16
IEDFAACK_01719 1.1e-239 ymfH S zinc protease
IEDFAACK_01720 3e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IEDFAACK_01721 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
IEDFAACK_01722 2.7e-143 ymfK S Protein of unknown function (DUF3388)
IEDFAACK_01723 3.5e-118 ymfM S protein conserved in bacteria
IEDFAACK_01724 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEDFAACK_01725 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
IEDFAACK_01726 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IEDFAACK_01727 9.1e-212 pbpX V Beta-lactamase
IEDFAACK_01728 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
IEDFAACK_01729 1.9e-152 ymdB S protein conserved in bacteria
IEDFAACK_01730 1.2e-36 spoVS S Stage V sporulation protein S
IEDFAACK_01731 2.1e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IEDFAACK_01732 2.3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IEDFAACK_01733 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IEDFAACK_01734 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IEDFAACK_01735 2.2e-88 cotE S Spore coat protein
IEDFAACK_01736 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IEDFAACK_01737 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IEDFAACK_01738 4.1e-67 S Regulatory protein YrvL
IEDFAACK_01740 3.5e-97 ymcC S Membrane
IEDFAACK_01741 4.4e-109 pksA K Transcriptional regulator
IEDFAACK_01742 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
IEDFAACK_01743 9.2e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IEDFAACK_01745 6e-185 pksD Q Acyl transferase domain
IEDFAACK_01746 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IEDFAACK_01747 1.4e-37 acpK IQ Phosphopantetheine attachment site
IEDFAACK_01748 3.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IEDFAACK_01749 5.1e-245 pksG 2.3.3.10 I synthase
IEDFAACK_01750 1.2e-140 pksH 4.2.1.18 I enoyl-CoA hydratase
IEDFAACK_01751 2.3e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IEDFAACK_01752 0.0 rhiB IQ polyketide synthase
IEDFAACK_01753 0.0 pfaA Q Polyketide synthase of type I
IEDFAACK_01754 7.9e-210 pfaA 4.1.1.35 GT4 IQ polyketide synthase
IEDFAACK_01755 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
IEDFAACK_01756 0.0 dhbF IQ polyketide synthase
IEDFAACK_01757 0.0 pks13 HQ Beta-ketoacyl synthase
IEDFAACK_01758 3.1e-231 cypA C Cytochrome P450
IEDFAACK_01759 2.9e-60 ymzB
IEDFAACK_01760 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
IEDFAACK_01761 8.6e-251 aprX O Belongs to the peptidase S8 family
IEDFAACK_01762 1.9e-07 K Transcriptional regulator
IEDFAACK_01763 2.1e-126 ymaC S Replication protein
IEDFAACK_01764 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
IEDFAACK_01765 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
IEDFAACK_01766 4.1e-50 ebrA P Small Multidrug Resistance protein
IEDFAACK_01768 2.1e-46 ymaF S YmaF family
IEDFAACK_01769 2.3e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IEDFAACK_01770 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IEDFAACK_01771 8.2e-23
IEDFAACK_01772 4.5e-22 ymzA
IEDFAACK_01773 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
IEDFAACK_01774 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEDFAACK_01775 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEDFAACK_01776 2e-109 ymaB
IEDFAACK_01777 8.8e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IEDFAACK_01778 1.7e-176 spoVK O stage V sporulation protein K
IEDFAACK_01779 7.9e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IEDFAACK_01780 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IEDFAACK_01781 1.1e-68 glnR K transcriptional
IEDFAACK_01782 7e-261 glnA 6.3.1.2 E glutamine synthetase
IEDFAACK_01783 3.8e-10
IEDFAACK_01784 4.6e-31
IEDFAACK_01785 3.2e-37
IEDFAACK_01786 9.8e-89 G SMI1-KNR4 cell-wall
IEDFAACK_01787 1.1e-10 ynaC
IEDFAACK_01788 2.1e-103 ynaC
IEDFAACK_01789 6.8e-98 ynaD J Acetyltransferase (GNAT) domain
IEDFAACK_01792 5.5e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
IEDFAACK_01793 3.5e-255 xynT G MFS/sugar transport protein
IEDFAACK_01794 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
IEDFAACK_01795 1.4e-212 xylR GK ROK family
IEDFAACK_01796 2.1e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
IEDFAACK_01797 3.4e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
IEDFAACK_01798 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
IEDFAACK_01799 4.7e-255 iolT EGP Major facilitator Superfamily
IEDFAACK_01800 3.8e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEDFAACK_01801 1.9e-80 yncE S Protein of unknown function (DUF2691)
IEDFAACK_01802 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
IEDFAACK_01803 1.3e-13
IEDFAACK_01806 1.2e-146 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IEDFAACK_01808 1.7e-120 S Domain of unknown function, YrpD
IEDFAACK_01811 6.7e-24 tatA U protein secretion
IEDFAACK_01812 2.6e-70
IEDFAACK_01813 2e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
IEDFAACK_01816 3.2e-281 gerAA EG Spore germination protein
IEDFAACK_01817 2.1e-194 gerAB U Spore germination
IEDFAACK_01818 1.1e-212 gerLC S Spore germination protein
IEDFAACK_01819 1.8e-150 yndG S DoxX-like family
IEDFAACK_01820 7.1e-115 yndH S Domain of unknown function (DUF4166)
IEDFAACK_01821 8.5e-309 yndJ S YndJ-like protein
IEDFAACK_01823 8.1e-137 yndL S Replication protein
IEDFAACK_01824 5.8e-74 yndM S Protein of unknown function (DUF2512)
IEDFAACK_01825 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IEDFAACK_01826 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IEDFAACK_01827 7.6e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IEDFAACK_01828 3.6e-109 yneB L resolvase
IEDFAACK_01829 1.4e-31 ynzC S UPF0291 protein
IEDFAACK_01830 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IEDFAACK_01831 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
IEDFAACK_01832 1.8e-28 yneF S UPF0154 protein
IEDFAACK_01833 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
IEDFAACK_01834 1.2e-126 ccdA O cytochrome c biogenesis protein
IEDFAACK_01835 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
IEDFAACK_01836 1.9e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
IEDFAACK_01837 4.2e-74 yneK S Protein of unknown function (DUF2621)
IEDFAACK_01838 2.2e-63 hspX O Spore coat protein
IEDFAACK_01839 3.9e-19 sspP S Belongs to the SspP family
IEDFAACK_01840 2.5e-14 sspO S Belongs to the SspO family
IEDFAACK_01841 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IEDFAACK_01842 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IEDFAACK_01844 3.1e-08 sspN S Small acid-soluble spore protein N family
IEDFAACK_01845 3.9e-35 tlp S Belongs to the Tlp family
IEDFAACK_01846 1.2e-73 yneP S Thioesterase-like superfamily
IEDFAACK_01847 4.9e-53 yneQ
IEDFAACK_01848 4.1e-49 yneR S Belongs to the HesB IscA family
IEDFAACK_01849 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IEDFAACK_01850 6.6e-69 yccU S CoA-binding protein
IEDFAACK_01851 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IEDFAACK_01852 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IEDFAACK_01853 2.3e-12
IEDFAACK_01854 1.3e-57 ynfC
IEDFAACK_01855 5.3e-251 agcS E Sodium alanine symporter
IEDFAACK_01856 1.4e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
IEDFAACK_01858 7.2e-247 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
IEDFAACK_01859 4.4e-291 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
IEDFAACK_01860 1.6e-79 yngA S membrane
IEDFAACK_01861 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IEDFAACK_01862 1.2e-103 yngC S membrane-associated protein
IEDFAACK_01863 2.1e-232 nrnB S phosphohydrolase (DHH superfamily)
IEDFAACK_01864 1.3e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IEDFAACK_01865 5.4e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IEDFAACK_01866 1.2e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
IEDFAACK_01867 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
IEDFAACK_01868 1.1e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
IEDFAACK_01869 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IEDFAACK_01870 9.8e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
IEDFAACK_01871 6.3e-32 S Family of unknown function (DUF5367)
IEDFAACK_01872 2e-304 yngK T Glycosyl hydrolase-like 10
IEDFAACK_01873 1.1e-63 yngL S Protein of unknown function (DUF1360)
IEDFAACK_01874 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
IEDFAACK_01875 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_01876 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_01877 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_01878 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_01879 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_01880 9.8e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
IEDFAACK_01881 8.4e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
IEDFAACK_01882 2.3e-246 yoeA V MATE efflux family protein
IEDFAACK_01883 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
IEDFAACK_01885 6.5e-96 L Integrase
IEDFAACK_01886 3e-34 yoeD G Helix-turn-helix domain
IEDFAACK_01887 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IEDFAACK_01888 1.6e-123 gltR1 K Transcriptional regulator
IEDFAACK_01889 1.7e-17 gltR1 K Transcriptional regulator
IEDFAACK_01890 2.8e-182 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IEDFAACK_01891 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IEDFAACK_01892 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
IEDFAACK_01893 7.8e-155 gltC K Transcriptional regulator
IEDFAACK_01894 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IEDFAACK_01895 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IEDFAACK_01896 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IEDFAACK_01897 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFAACK_01898 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
IEDFAACK_01899 1.3e-134 yoxB
IEDFAACK_01900 2.7e-94 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IEDFAACK_01901 1.2e-233 yoaB EGP Major facilitator Superfamily
IEDFAACK_01902 1.3e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
IEDFAACK_01903 1.3e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEDFAACK_01904 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IEDFAACK_01905 1.1e-33 yoaF
IEDFAACK_01906 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
IEDFAACK_01907 2.6e-13
IEDFAACK_01908 8.2e-37 S Protein of unknown function (DUF4025)
IEDFAACK_01909 2.7e-180 mcpU NT methyl-accepting chemotaxis protein
IEDFAACK_01910 1.4e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
IEDFAACK_01911 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
IEDFAACK_01912 5e-91 yoaK S Membrane
IEDFAACK_01913 8.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
IEDFAACK_01914 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
IEDFAACK_01917 8.7e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
IEDFAACK_01920 4e-84
IEDFAACK_01921 7.1e-172 yoaR V vancomycin resistance protein
IEDFAACK_01922 3.6e-74 yoaS S Protein of unknown function (DUF2975)
IEDFAACK_01923 4.4e-30 yozG K Transcriptional regulator
IEDFAACK_01924 3.1e-147 yoaT S Protein of unknown function (DUF817)
IEDFAACK_01925 2.5e-158 yoaU K LysR substrate binding domain
IEDFAACK_01926 2e-155 yijE EG EamA-like transporter family
IEDFAACK_01927 1.3e-75 yoaW
IEDFAACK_01928 1e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
IEDFAACK_01929 4.1e-167 bla 3.5.2.6 V beta-lactamase
IEDFAACK_01932 1.8e-201 pps 2.7.9.2 GT phosphoenolpyruvate synthase
IEDFAACK_01933 6.1e-280 pps 2.7.9.2 GT phosphoenolpyruvate synthase
IEDFAACK_01934 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
IEDFAACK_01935 1.4e-37 S TM2 domain
IEDFAACK_01936 3.8e-54 K Helix-turn-helix
IEDFAACK_01937 2.2e-63 yoaQ S Evidence 4 Homologs of previously reported genes of
IEDFAACK_01938 2.1e-114 yoqW S Belongs to the SOS response-associated peptidase family
IEDFAACK_01939 3e-204 S aspartate phosphatase
IEDFAACK_01941 3.3e-98 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEDFAACK_01942 5.1e-15 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEDFAACK_01943 4.7e-161 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IEDFAACK_01944 2.4e-101 yokH G SMI1 / KNR4 family
IEDFAACK_01945 3.7e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
IEDFAACK_01946 3.5e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
IEDFAACK_01947 6.1e-134 yobQ K helix_turn_helix, arabinose operon control protein
IEDFAACK_01948 3.1e-141 yobR 2.3.1.1 J FR47-like protein
IEDFAACK_01949 6.9e-96 yobS K Transcriptional regulator
IEDFAACK_01950 7.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
IEDFAACK_01951 1.6e-82 yobU K Bacterial transcription activator, effector binding domain
IEDFAACK_01952 6e-174 yobV K WYL domain
IEDFAACK_01953 1.8e-90 yobW
IEDFAACK_01954 1e-51 czrA K transcriptional
IEDFAACK_01955 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IEDFAACK_01956 1.5e-92 yozB S membrane
IEDFAACK_01957 3.3e-141
IEDFAACK_01958 1.5e-91 yocC
IEDFAACK_01959 7.1e-186 yocD 3.4.17.13 V peptidase S66
IEDFAACK_01960 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
IEDFAACK_01961 7.1e-198 desK 2.7.13.3 T Histidine kinase
IEDFAACK_01962 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEDFAACK_01963 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
IEDFAACK_01964 0.0 recQ 3.6.4.12 L DNA helicase
IEDFAACK_01966 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEDFAACK_01967 3.3e-83 dksA T general stress protein
IEDFAACK_01968 5.4e-53 yocL
IEDFAACK_01969 6.2e-32
IEDFAACK_01970 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
IEDFAACK_01971 1.1e-40 yozN
IEDFAACK_01972 1.9e-36 yocN
IEDFAACK_01973 4.2e-56 yozO S Bacterial PH domain
IEDFAACK_01974 2.7e-31 yozC
IEDFAACK_01975 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
IEDFAACK_01976 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
IEDFAACK_01977 6e-165 sodA 1.15.1.1 P Superoxide dismutase
IEDFAACK_01978 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IEDFAACK_01979 1.1e-167 yocS S -transporter
IEDFAACK_01980 9.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IEDFAACK_01981 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IEDFAACK_01982 0.0 yojO P Von Willebrand factor
IEDFAACK_01983 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
IEDFAACK_01984 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IEDFAACK_01985 1.4e-191 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IEDFAACK_01986 1.2e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
IEDFAACK_01987 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IEDFAACK_01989 2.3e-243 norM V Multidrug efflux pump
IEDFAACK_01990 4.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IEDFAACK_01991 2.1e-125 yojG S deacetylase
IEDFAACK_01992 2.2e-60 yojF S Protein of unknown function (DUF1806)
IEDFAACK_01993 1.5e-43
IEDFAACK_01994 1.9e-161 rarD S -transporter
IEDFAACK_01995 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
IEDFAACK_01996 3.4e-09
IEDFAACK_01997 4.2e-205 gntP EG COG2610 H gluconate symporter and related permeases
IEDFAACK_01998 8e-64 yodA S tautomerase
IEDFAACK_01999 4.4e-55 yodB K transcriptional
IEDFAACK_02000 1.4e-107 yodC C nitroreductase
IEDFAACK_02001 3.8e-113 mhqD S Carboxylesterase
IEDFAACK_02002 6.4e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
IEDFAACK_02003 6.2e-28 S Protein of unknown function (DUF3311)
IEDFAACK_02004 6.9e-80 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEDFAACK_02005 4.3e-34 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEDFAACK_02006 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IEDFAACK_02007 6.3e-128 yodH Q Methyltransferase
IEDFAACK_02008 1.5e-23 yodI
IEDFAACK_02009 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IEDFAACK_02010 9.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IEDFAACK_02011 5.3e-09
IEDFAACK_02012 3.6e-54 yodL S YodL-like
IEDFAACK_02013 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
IEDFAACK_02014 2.8e-24 yozD S YozD-like protein
IEDFAACK_02016 6e-123 yodN
IEDFAACK_02017 1.4e-36 yozE S Belongs to the UPF0346 family
IEDFAACK_02018 7e-46 yokU S YokU-like protein, putative antitoxin
IEDFAACK_02019 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
IEDFAACK_02020 2.3e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
IEDFAACK_02021 1.5e-255 yodQ 3.5.1.16 E Acetylornithine deacetylase
IEDFAACK_02022 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IEDFAACK_02023 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEDFAACK_02024 2.2e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEDFAACK_02026 1.8e-144 yiiD K acetyltransferase
IEDFAACK_02027 6.8e-253 cgeD M maturation of the outermost layer of the spore
IEDFAACK_02028 3.5e-38 cgeC
IEDFAACK_02029 1.2e-65 cgeA
IEDFAACK_02030 6.3e-187 cgeB S Spore maturation protein
IEDFAACK_02031 5.8e-211 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
IEDFAACK_02032 3.5e-62 4.2.1.115 GM Polysaccharide biosynthesis protein
IEDFAACK_02033 1.5e-30 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IEDFAACK_02034 1.9e-10 K Cro/C1-type HTH DNA-binding domain
IEDFAACK_02036 2.3e-161 S Calcineurin-like phosphoesterase
IEDFAACK_02037 2.5e-30 sspB S spore protein
IEDFAACK_02041 9.8e-36 O Glutaredoxin
IEDFAACK_02042 5.2e-53 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEDFAACK_02043 4.5e-94 L HNH endonuclease
IEDFAACK_02044 3.1e-104 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEDFAACK_02045 1.7e-176 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEDFAACK_02046 3.1e-40 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEDFAACK_02047 2e-121 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
IEDFAACK_02048 6.9e-63 S NrdI Flavodoxin like
IEDFAACK_02054 1.7e-74 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
IEDFAACK_02059 0.0 M Parallel beta-helix repeats
IEDFAACK_02060 9.4e-147 S Pfam:DUF867
IEDFAACK_02062 1.6e-128 yoqW S Belongs to the SOS response-associated peptidase family
IEDFAACK_02063 1.1e-108 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
IEDFAACK_02068 9.8e-88 S Protein of unknown function (DUF1273)
IEDFAACK_02073 1.7e-56
IEDFAACK_02075 0.0
IEDFAACK_02076 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IEDFAACK_02078 2.8e-224 S hydrolase activity
IEDFAACK_02080 1.8e-170
IEDFAACK_02081 0.0 gp17a S Terminase-like family
IEDFAACK_02082 2.2e-279
IEDFAACK_02083 6.2e-263
IEDFAACK_02084 1.7e-93
IEDFAACK_02085 1.3e-185
IEDFAACK_02086 1.1e-80
IEDFAACK_02087 1.1e-68
IEDFAACK_02089 1.4e-121
IEDFAACK_02090 1.3e-90
IEDFAACK_02091 8.1e-131
IEDFAACK_02092 5.1e-89
IEDFAACK_02095 1.2e-34
IEDFAACK_02096 1.8e-84
IEDFAACK_02097 6.7e-64
IEDFAACK_02098 1.2e-191 xerH A Belongs to the 'phage' integrase family
IEDFAACK_02101 1.1e-108
IEDFAACK_02102 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IEDFAACK_02103 7e-71
IEDFAACK_02104 1.5e-220 S impB/mucB/samB family C-terminal domain
IEDFAACK_02105 1.7e-46 S YolD-like protein
IEDFAACK_02106 1.8e-98 J Acetyltransferase (GNAT) domain
IEDFAACK_02107 8.7e-99 yokK S SMI1 / KNR4 family
IEDFAACK_02108 2.8e-93 yokJ S SMI1 / KNR4 family (SUKH-1)
IEDFAACK_02109 3.9e-128 UW nuclease activity
IEDFAACK_02110 2.4e-42 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IEDFAACK_02111 1.3e-48 yokH G SMI1 / KNR4 family
IEDFAACK_02112 1.2e-110 yokF 3.1.31.1 L RNA catabolic process
IEDFAACK_02113 1.6e-82 S Bacterial PH domain
IEDFAACK_02114 8.4e-156 aacC 2.3.1.81 V aminoglycoside
IEDFAACK_02117 8.9e-95
IEDFAACK_02118 1.3e-95 4.2.1.115 GM Polysaccharide biosynthesis protein
IEDFAACK_02119 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IEDFAACK_02120 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IEDFAACK_02121 1.6e-70 ypoP K transcriptional
IEDFAACK_02122 1.7e-222 mepA V MATE efflux family protein
IEDFAACK_02123 1.2e-28 ypmT S Uncharacterized ympT
IEDFAACK_02124 1.1e-98 ypmS S protein conserved in bacteria
IEDFAACK_02125 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
IEDFAACK_02126 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IEDFAACK_02127 8.9e-40 ypmP S Protein of unknown function (DUF2535)
IEDFAACK_02128 2e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IEDFAACK_02129 6.1e-185 pspF K Transcriptional regulator
IEDFAACK_02130 4.2e-110 hlyIII S protein, Hemolysin III
IEDFAACK_02131 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IEDFAACK_02132 1.5e-94 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IEDFAACK_02133 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IEDFAACK_02134 1.2e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
IEDFAACK_02135 2.5e-112 ypjP S YpjP-like protein
IEDFAACK_02136 1.7e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
IEDFAACK_02137 1.7e-75 yphP S Belongs to the UPF0403 family
IEDFAACK_02138 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IEDFAACK_02139 2.2e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
IEDFAACK_02140 1.2e-106 ypgQ S phosphohydrolase
IEDFAACK_02141 6.8e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IEDFAACK_02142 8.1e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IEDFAACK_02144 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IEDFAACK_02145 7.9e-31 cspD K Cold-shock protein
IEDFAACK_02146 3.8e-16 degR
IEDFAACK_02147 8.1e-31 S Protein of unknown function (DUF2564)
IEDFAACK_02148 3e-29 ypeQ S Zinc-finger
IEDFAACK_02149 8.3e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
IEDFAACK_02150 1.5e-104 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IEDFAACK_02151 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
IEDFAACK_02153 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
IEDFAACK_02154 2e-07
IEDFAACK_02155 1e-38 ypbS S Protein of unknown function (DUF2533)
IEDFAACK_02156 0.0 ypbR S Dynamin family
IEDFAACK_02158 6.7e-87 ypbQ S protein conserved in bacteria
IEDFAACK_02159 1.4e-206 bcsA Q Naringenin-chalcone synthase
IEDFAACK_02160 9.5e-226 pbuX F xanthine
IEDFAACK_02161 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IEDFAACK_02162 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IEDFAACK_02163 6.6e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IEDFAACK_02164 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
IEDFAACK_02165 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
IEDFAACK_02166 2.2e-185 ptxS K transcriptional
IEDFAACK_02167 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IEDFAACK_02168 2.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEDFAACK_02169 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
IEDFAACK_02171 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IEDFAACK_02172 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IEDFAACK_02173 2.8e-91 ypsA S Belongs to the UPF0398 family
IEDFAACK_02174 9.5e-236 yprB L RNase_H superfamily
IEDFAACK_02175 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IEDFAACK_02176 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
IEDFAACK_02177 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
IEDFAACK_02178 1e-47 yppG S YppG-like protein
IEDFAACK_02180 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
IEDFAACK_02183 2.8e-187 yppC S Protein of unknown function (DUF2515)
IEDFAACK_02184 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IEDFAACK_02185 1.4e-199 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
IEDFAACK_02186 3.5e-16 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
IEDFAACK_02187 2.7e-71 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
IEDFAACK_02188 4.7e-93 ypoC
IEDFAACK_02189 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IEDFAACK_02190 5.7e-129 dnaD L DNA replication protein DnaD
IEDFAACK_02191 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
IEDFAACK_02192 6.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IEDFAACK_02193 2.2e-79 ypmB S protein conserved in bacteria
IEDFAACK_02194 6.7e-23 ypmA S Protein of unknown function (DUF4264)
IEDFAACK_02195 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IEDFAACK_02196 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IEDFAACK_02197 1.4e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IEDFAACK_02198 5.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IEDFAACK_02199 3.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IEDFAACK_02200 4.6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IEDFAACK_02201 7.7e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
IEDFAACK_02202 4.9e-128 bshB1 S proteins, LmbE homologs
IEDFAACK_02203 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
IEDFAACK_02204 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IEDFAACK_02205 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
IEDFAACK_02206 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
IEDFAACK_02207 1.5e-141 ypjB S sporulation protein
IEDFAACK_02208 3.1e-99 ypjA S membrane
IEDFAACK_02209 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
IEDFAACK_02210 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
IEDFAACK_02211 1.1e-96 qcrA C Menaquinol-cytochrome c reductase
IEDFAACK_02212 2.7e-76 ypiF S Protein of unknown function (DUF2487)
IEDFAACK_02213 2.8e-99 ypiB S Belongs to the UPF0302 family
IEDFAACK_02214 4.1e-234 S COG0457 FOG TPR repeat
IEDFAACK_02215 2.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IEDFAACK_02216 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IEDFAACK_02217 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IEDFAACK_02218 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IEDFAACK_02219 2.2e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IEDFAACK_02220 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IEDFAACK_02221 4.3e-114 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IEDFAACK_02222 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IEDFAACK_02223 2.1e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IEDFAACK_02224 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IEDFAACK_02225 1.7e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IEDFAACK_02226 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IEDFAACK_02227 4.2e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
IEDFAACK_02228 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IEDFAACK_02229 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IEDFAACK_02230 7.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IEDFAACK_02231 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IEDFAACK_02232 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IEDFAACK_02233 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
IEDFAACK_02234 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IEDFAACK_02235 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IEDFAACK_02236 6e-137 yphF
IEDFAACK_02237 1.2e-18 yphE S Protein of unknown function (DUF2768)
IEDFAACK_02238 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IEDFAACK_02239 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IEDFAACK_02240 2.1e-28 ypzH
IEDFAACK_02241 3.3e-161 seaA S YIEGIA protein
IEDFAACK_02242 3.9e-102 yphA
IEDFAACK_02243 1e-07 S YpzI-like protein
IEDFAACK_02244 3.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IEDFAACK_02245 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
IEDFAACK_02246 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IEDFAACK_02247 1.8e-23 S Family of unknown function (DUF5359)
IEDFAACK_02248 3.9e-111 ypfA M Flagellar protein YcgR
IEDFAACK_02249 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
IEDFAACK_02250 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
IEDFAACK_02251 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
IEDFAACK_02252 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
IEDFAACK_02253 2.2e-243 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IEDFAACK_02254 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IEDFAACK_02255 6.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
IEDFAACK_02256 2.8e-81 ypbF S Protein of unknown function (DUF2663)
IEDFAACK_02257 3.9e-80 ypbE M Lysin motif
IEDFAACK_02258 1.1e-99 ypbD S metal-dependent membrane protease
IEDFAACK_02259 9.2e-286 recQ 3.6.4.12 L DNA helicase
IEDFAACK_02260 1.8e-198 ypbB 5.1.3.1 S protein conserved in bacteria
IEDFAACK_02261 4.7e-41 fer C Ferredoxin
IEDFAACK_02262 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IEDFAACK_02263 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEDFAACK_02264 5.5e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IEDFAACK_02265 1.5e-200 rsiX
IEDFAACK_02266 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
IEDFAACK_02267 0.0 resE 2.7.13.3 T Histidine kinase
IEDFAACK_02268 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_02269 2.6e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IEDFAACK_02270 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
IEDFAACK_02271 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IEDFAACK_02272 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IEDFAACK_02273 1.9e-87 spmB S Spore maturation protein
IEDFAACK_02274 3.5e-103 spmA S Spore maturation protein
IEDFAACK_02275 1.5e-211 dacB 3.4.16.4 M Belongs to the peptidase S11 family
IEDFAACK_02276 7.6e-97 ypuI S Protein of unknown function (DUF3907)
IEDFAACK_02277 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IEDFAACK_02278 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IEDFAACK_02279 1.2e-91 ypuF S Domain of unknown function (DUF309)
IEDFAACK_02280 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEDFAACK_02281 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IEDFAACK_02282 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IEDFAACK_02283 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
IEDFAACK_02284 1.1e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEDFAACK_02285 7.8e-55 ypuD
IEDFAACK_02286 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IEDFAACK_02287 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
IEDFAACK_02288 3.4e-13 S PAP2 superfamily
IEDFAACK_02289 1.2e-07 eaeH M Domain of Unknown Function (DUF1259)
IEDFAACK_02291 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IEDFAACK_02292 3.6e-149 ypuA S Secreted protein
IEDFAACK_02293 2.6e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IEDFAACK_02294 1.4e-273 spoVAF EG Stage V sporulation protein AF
IEDFAACK_02295 1.4e-110 spoVAEA S stage V sporulation protein
IEDFAACK_02296 2.2e-57 spoVAEB S stage V sporulation protein
IEDFAACK_02297 9e-192 spoVAD I Stage V sporulation protein AD
IEDFAACK_02298 2.3e-78 spoVAC S stage V sporulation protein AC
IEDFAACK_02299 1e-67 spoVAB S Stage V sporulation protein AB
IEDFAACK_02300 9.6e-112 spoVAA S Stage V sporulation protein AA
IEDFAACK_02301 9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEDFAACK_02302 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IEDFAACK_02303 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
IEDFAACK_02304 1.3e-210 dacF 3.4.16.4 M Belongs to the peptidase S11 family
IEDFAACK_02305 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IEDFAACK_02306 3.3e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IEDFAACK_02307 4.4e-166 xerD L recombinase XerD
IEDFAACK_02308 3.7e-37 S Protein of unknown function (DUF4227)
IEDFAACK_02309 2.4e-80 fur P Belongs to the Fur family
IEDFAACK_02310 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IEDFAACK_02311 5.5e-30 yqkK
IEDFAACK_02312 8e-241 mleA 1.1.1.38 C malic enzyme
IEDFAACK_02313 9.1e-235 mleN C Na H antiporter
IEDFAACK_02314 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
IEDFAACK_02315 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
IEDFAACK_02316 4.5e-58 ansR K Transcriptional regulator
IEDFAACK_02317 9e-220 yqxK 3.6.4.12 L DNA helicase
IEDFAACK_02318 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
IEDFAACK_02320 1.8e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
IEDFAACK_02321 3.1e-12 yqkE S Protein of unknown function (DUF3886)
IEDFAACK_02322 2.5e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
IEDFAACK_02323 9.4e-39 yqkC S Protein of unknown function (DUF2552)
IEDFAACK_02324 2.8e-54 yqkB S Belongs to the HesB IscA family
IEDFAACK_02325 1.1e-192 yqkA K GrpB protein
IEDFAACK_02326 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
IEDFAACK_02327 2e-85 yqjY K acetyltransferase
IEDFAACK_02328 1.7e-49 S YolD-like protein
IEDFAACK_02329 1.7e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEDFAACK_02331 3.7e-224 yqjV G Major Facilitator Superfamily
IEDFAACK_02333 2.1e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEDFAACK_02334 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IEDFAACK_02335 7.1e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IEDFAACK_02336 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFAACK_02337 2.2e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
IEDFAACK_02338 1.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IEDFAACK_02339 2.3e-311 rocB E arginine degradation protein
IEDFAACK_02340 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IEDFAACK_02341 1.7e-142 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IEDFAACK_02342 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IEDFAACK_02343 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IEDFAACK_02344 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IEDFAACK_02345 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IEDFAACK_02346 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEDFAACK_02347 4.5e-24 yqzJ
IEDFAACK_02348 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IEDFAACK_02349 1.3e-139 yqjF S Uncharacterized conserved protein (COG2071)
IEDFAACK_02350 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
IEDFAACK_02351 1e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IEDFAACK_02352 4.2e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
IEDFAACK_02354 2.3e-98 yqjB S protein conserved in bacteria
IEDFAACK_02355 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
IEDFAACK_02356 7.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IEDFAACK_02357 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
IEDFAACK_02358 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
IEDFAACK_02359 9.3e-77 yqiW S Belongs to the UPF0403 family
IEDFAACK_02360 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IEDFAACK_02361 1.4e-207 norA EGP Major facilitator Superfamily
IEDFAACK_02362 2.6e-152 bmrR K helix_turn_helix, mercury resistance
IEDFAACK_02363 7.5e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IEDFAACK_02364 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IEDFAACK_02365 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IEDFAACK_02366 1.4e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IEDFAACK_02367 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
IEDFAACK_02368 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
IEDFAACK_02369 5.1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
IEDFAACK_02370 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
IEDFAACK_02371 4e-34 yqzF S Protein of unknown function (DUF2627)
IEDFAACK_02372 1.5e-161 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IEDFAACK_02373 1.8e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
IEDFAACK_02374 3.5e-205 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
IEDFAACK_02375 4.8e-210 mmgC I acyl-CoA dehydrogenase
IEDFAACK_02376 2.2e-154 hbdA 1.1.1.157 I Dehydrogenase
IEDFAACK_02377 1.3e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
IEDFAACK_02378 1.1e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IEDFAACK_02379 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
IEDFAACK_02380 6e-27
IEDFAACK_02381 2.3e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IEDFAACK_02383 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IEDFAACK_02384 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
IEDFAACK_02385 1.9e-306 recN L May be involved in recombinational repair of damaged DNA
IEDFAACK_02386 1.7e-78 argR K Regulates arginine biosynthesis genes
IEDFAACK_02387 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
IEDFAACK_02388 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IEDFAACK_02389 6.5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IEDFAACK_02390 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEDFAACK_02391 8.4e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEDFAACK_02392 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IEDFAACK_02393 7.4e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IEDFAACK_02394 1.8e-66 yqhY S protein conserved in bacteria
IEDFAACK_02395 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IEDFAACK_02396 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IEDFAACK_02397 1.6e-85 spoIIIAH S SpoIIIAH-like protein
IEDFAACK_02398 6.9e-103 spoIIIAG S stage III sporulation protein AG
IEDFAACK_02399 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
IEDFAACK_02400 8.4e-197 spoIIIAE S stage III sporulation protein AE
IEDFAACK_02401 2.3e-58 spoIIIAD S Stage III sporulation protein AD
IEDFAACK_02402 7.6e-29 spoIIIAC S stage III sporulation protein AC
IEDFAACK_02403 3.2e-84 spoIIIAB S Stage III sporulation protein
IEDFAACK_02404 1e-170 spoIIIAA S stage III sporulation protein AA
IEDFAACK_02405 7.9e-37 yqhV S Protein of unknown function (DUF2619)
IEDFAACK_02406 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IEDFAACK_02407 1.7e-172 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IEDFAACK_02408 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
IEDFAACK_02409 6.6e-93 yqhR S Conserved membrane protein YqhR
IEDFAACK_02410 3.4e-172 yqhQ S Protein of unknown function (DUF1385)
IEDFAACK_02411 2.2e-61 yqhP
IEDFAACK_02412 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
IEDFAACK_02413 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IEDFAACK_02414 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IEDFAACK_02415 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
IEDFAACK_02416 4.1e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IEDFAACK_02417 6.4e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IEDFAACK_02418 2.4e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
IEDFAACK_02419 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IEDFAACK_02420 7.1e-152 yqhG S Bacterial protein YqhG of unknown function
IEDFAACK_02421 1.2e-24 sinI S Anti-repressor SinI
IEDFAACK_02422 1e-54 sinR K transcriptional
IEDFAACK_02423 1.9e-141 tasA S Cell division protein FtsN
IEDFAACK_02424 7.4e-58 sipW 3.4.21.89 U Signal peptidase
IEDFAACK_02425 5.1e-115 yqxM
IEDFAACK_02426 2.1e-53 yqzG S Protein of unknown function (DUF3889)
IEDFAACK_02427 1.4e-26 yqzE S YqzE-like protein
IEDFAACK_02428 3e-44 S ComG operon protein 7
IEDFAACK_02429 1.7e-34 comGF U Putative Competence protein ComGF
IEDFAACK_02430 9e-59 comGE
IEDFAACK_02431 5.4e-69 gspH NU protein transport across the cell outer membrane
IEDFAACK_02432 6.8e-47 comGC U Required for transformation and DNA binding
IEDFAACK_02433 1.1e-173 comGB NU COG1459 Type II secretory pathway, component PulF
IEDFAACK_02434 1.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IEDFAACK_02436 5.2e-173 corA P Mg2 transporter protein
IEDFAACK_02437 4.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IEDFAACK_02438 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IEDFAACK_02440 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
IEDFAACK_02441 1.8e-37 yqgY S Protein of unknown function (DUF2626)
IEDFAACK_02442 8e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IEDFAACK_02443 8.9e-23 yqgW S Protein of unknown function (DUF2759)
IEDFAACK_02444 6.9e-50 yqgV S Thiamine-binding protein
IEDFAACK_02445 3.3e-197 yqgU
IEDFAACK_02446 2.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
IEDFAACK_02447 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IEDFAACK_02448 5.2e-181 glcK 2.7.1.2 G Glucokinase
IEDFAACK_02449 3.1e-33 yqgQ S Protein conserved in bacteria
IEDFAACK_02450 2e-264 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IEDFAACK_02451 2.5e-09 yqgO
IEDFAACK_02452 1.1e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IEDFAACK_02453 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IEDFAACK_02454 1.6e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
IEDFAACK_02456 2.1e-50 yqzD
IEDFAACK_02457 7e-75 yqzC S YceG-like family
IEDFAACK_02458 1.9e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEDFAACK_02459 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEDFAACK_02460 1.3e-157 pstA P Phosphate transport system permease
IEDFAACK_02461 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
IEDFAACK_02462 9e-143 pstS P Phosphate
IEDFAACK_02463 5e-193 pbpA 3.4.16.4 M penicillin-binding protein
IEDFAACK_02464 2.5e-231 yqgE EGP Major facilitator superfamily
IEDFAACK_02465 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
IEDFAACK_02466 4e-73 yqgC S protein conserved in bacteria
IEDFAACK_02467 3.9e-131 yqgB S Protein of unknown function (DUF1189)
IEDFAACK_02468 5.2e-47 yqfZ M LysM domain
IEDFAACK_02469 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IEDFAACK_02470 4.3e-62 yqfX S membrane
IEDFAACK_02471 1e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
IEDFAACK_02472 4.2e-77 zur P Belongs to the Fur family
IEDFAACK_02473 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IEDFAACK_02474 2.1e-36 yqfT S Protein of unknown function (DUF2624)
IEDFAACK_02475 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IEDFAACK_02476 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IEDFAACK_02477 2.1e-12 yqfQ S YqfQ-like protein
IEDFAACK_02478 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IEDFAACK_02479 1.3e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IEDFAACK_02480 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
IEDFAACK_02481 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
IEDFAACK_02482 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IEDFAACK_02483 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IEDFAACK_02484 1.7e-87 yaiI S Belongs to the UPF0178 family
IEDFAACK_02485 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IEDFAACK_02486 4.5e-112 ccpN K CBS domain
IEDFAACK_02487 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IEDFAACK_02488 5.7e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IEDFAACK_02489 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
IEDFAACK_02490 8.4e-19 S YqzL-like protein
IEDFAACK_02491 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IEDFAACK_02492 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IEDFAACK_02493 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IEDFAACK_02494 6.7e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IEDFAACK_02495 0.0 yqfF S membrane-associated HD superfamily hydrolase
IEDFAACK_02497 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
IEDFAACK_02498 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
IEDFAACK_02499 2.7e-45 yqfC S sporulation protein YqfC
IEDFAACK_02500 1.5e-23 yqfB
IEDFAACK_02501 3.7e-121 yqfA S UPF0365 protein
IEDFAACK_02502 7.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
IEDFAACK_02503 2.5e-61 yqeY S Yqey-like protein
IEDFAACK_02504 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IEDFAACK_02505 8.2e-158 yqeW P COG1283 Na phosphate symporter
IEDFAACK_02506 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
IEDFAACK_02507 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IEDFAACK_02508 5.4e-175 prmA J Methylates ribosomal protein L11
IEDFAACK_02509 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IEDFAACK_02510 0.0 dnaK O Heat shock 70 kDa protein
IEDFAACK_02511 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IEDFAACK_02512 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IEDFAACK_02513 3.5e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
IEDFAACK_02514 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IEDFAACK_02515 4.7e-52 yqxA S Protein of unknown function (DUF3679)
IEDFAACK_02516 1.5e-222 spoIIP M stage II sporulation protein P
IEDFAACK_02517 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IEDFAACK_02518 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
IEDFAACK_02519 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
IEDFAACK_02520 4.1e-15 S YqzM-like protein
IEDFAACK_02521 0.0 comEC S Competence protein ComEC
IEDFAACK_02522 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
IEDFAACK_02523 6.2e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
IEDFAACK_02524 2.1e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IEDFAACK_02525 9.4e-138 yqeM Q Methyltransferase
IEDFAACK_02526 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IEDFAACK_02527 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IEDFAACK_02528 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IEDFAACK_02529 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
IEDFAACK_02530 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IEDFAACK_02531 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IEDFAACK_02532 5.3e-95 yqeG S hydrolase of the HAD superfamily
IEDFAACK_02534 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
IEDFAACK_02535 1.3e-134 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IEDFAACK_02536 1.2e-104 yqeD S SNARE associated Golgi protein
IEDFAACK_02537 3e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
IEDFAACK_02538 5.7e-132 yqeB
IEDFAACK_02539 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
IEDFAACK_02540 1.8e-60 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEDFAACK_02541 8.4e-31 cisA2 L Recombinase
IEDFAACK_02542 2.8e-26 S phage terminase, large subunit
IEDFAACK_02543 1.2e-56 yqaS L DNA packaging
IEDFAACK_02544 6.9e-75 L Transposase
IEDFAACK_02545 4.7e-29 yqaO S Phage-like element PBSX protein XtrA
IEDFAACK_02546 2.6e-71 rusA L Endodeoxyribonuclease RusA
IEDFAACK_02548 2.6e-59 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEDFAACK_02549 2.3e-110 yrkJ S membrane transporter protein
IEDFAACK_02550 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
IEDFAACK_02551 2.7e-205 yrkH P Rhodanese Homology Domain
IEDFAACK_02552 1.2e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
IEDFAACK_02553 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
IEDFAACK_02554 7.8e-39 yrkD S protein conserved in bacteria
IEDFAACK_02555 5e-21
IEDFAACK_02556 4.9e-107 yrkC G Cupin domain
IEDFAACK_02558 3.2e-147 bltR K helix_turn_helix, mercury resistance
IEDFAACK_02559 8.7e-210 blt EGP Major facilitator Superfamily
IEDFAACK_02560 3.4e-82 bltD 2.3.1.57 K FR47-like protein
IEDFAACK_02561 1.2e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IEDFAACK_02562 3.9e-16 S YrzO-like protein
IEDFAACK_02563 4.1e-170 yrdR EG EamA-like transporter family
IEDFAACK_02564 3.3e-158 yrdQ K Transcriptional regulator
IEDFAACK_02565 8.6e-198 trkA P Oxidoreductase
IEDFAACK_02566 5.1e-157 czcD P COG1230 Co Zn Cd efflux system component
IEDFAACK_02567 2.5e-25 yodA S tautomerase
IEDFAACK_02568 2.3e-227 brnQ E Component of the transport system for branched-chain amino acids
IEDFAACK_02569 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
IEDFAACK_02570 1.6e-137 azlC E AzlC protein
IEDFAACK_02571 6.3e-79 bkdR K helix_turn_helix ASNC type
IEDFAACK_02572 6.5e-44 yrdF K ribonuclease inhibitor
IEDFAACK_02573 1.6e-222 cypA C Cytochrome P450
IEDFAACK_02574 6.8e-19 K Acetyltransferase (GNAT) family
IEDFAACK_02575 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
IEDFAACK_02576 1.8e-55 S Protein of unknown function (DUF2568)
IEDFAACK_02578 1.9e-89 yrdA S DinB family
IEDFAACK_02579 4.2e-166 aadK G Streptomycin adenylyltransferase
IEDFAACK_02580 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IEDFAACK_02581 2.7e-143 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IEDFAACK_02582 8.1e-123 yrpD S Domain of unknown function, YrpD
IEDFAACK_02583 1.5e-114 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IEDFAACK_02584 3.3e-92 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
IEDFAACK_02585 1.9e-186 yrpG C Aldo/keto reductase family
IEDFAACK_02586 8.5e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IEDFAACK_02587 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEDFAACK_02588 1.1e-150 S Alpha beta hydrolase
IEDFAACK_02589 2.2e-60 T sh3 domain protein
IEDFAACK_02590 5.4e-61 T sh3 domain protein
IEDFAACK_02591 2.1e-64 E Glyoxalase-like domain
IEDFAACK_02592 3.4e-36 yraG
IEDFAACK_02593 6.4e-63 yraF M Spore coat protein
IEDFAACK_02594 5.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IEDFAACK_02595 7.5e-26 yraE
IEDFAACK_02596 1.1e-47 yraD M Spore coat protein
IEDFAACK_02597 4.3e-47 yraB K helix_turn_helix, mercury resistance
IEDFAACK_02598 1.6e-25 yphJ 4.1.1.44 S peroxiredoxin activity
IEDFAACK_02599 2.1e-196 adhA 1.1.1.1 C alcohol dehydrogenase
IEDFAACK_02600 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
IEDFAACK_02601 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
IEDFAACK_02602 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IEDFAACK_02603 2.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IEDFAACK_02604 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
IEDFAACK_02605 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
IEDFAACK_02606 0.0 levR K PTS system fructose IIA component
IEDFAACK_02607 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
IEDFAACK_02608 1.1e-105 yrhP E LysE type translocator
IEDFAACK_02609 7e-150 yrhO K Archaeal transcriptional regulator TrmB
IEDFAACK_02610 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IEDFAACK_02611 1e-148 rsiV S Protein of unknown function (DUF3298)
IEDFAACK_02612 0.0 yrhL I Acyltransferase family
IEDFAACK_02613 2.4e-21 yrhK S YrhK-like protein
IEDFAACK_02614 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IEDFAACK_02615 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
IEDFAACK_02616 1.1e-95 yrhH Q methyltransferase
IEDFAACK_02618 3e-142 focA P Formate nitrite
IEDFAACK_02619 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
IEDFAACK_02620 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
IEDFAACK_02621 5.4e-78 yrhD S Protein of unknown function (DUF1641)
IEDFAACK_02622 4.6e-35 yrhC S YrhC-like protein
IEDFAACK_02623 5.9e-208 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IEDFAACK_02624 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
IEDFAACK_02625 1.2e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IEDFAACK_02626 1.9e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
IEDFAACK_02627 1e-25 yrzA S Protein of unknown function (DUF2536)
IEDFAACK_02628 4.2e-63 yrrS S Protein of unknown function (DUF1510)
IEDFAACK_02629 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
IEDFAACK_02630 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IEDFAACK_02631 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
IEDFAACK_02632 2.7e-246 yegQ O COG0826 Collagenase and related proteases
IEDFAACK_02633 4.3e-172 yegQ O Peptidase U32
IEDFAACK_02634 8.6e-119 yrrM 2.1.1.104 S O-methyltransferase
IEDFAACK_02635 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IEDFAACK_02636 1.2e-45 yrzB S Belongs to the UPF0473 family
IEDFAACK_02637 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IEDFAACK_02638 1.7e-41 yrzL S Belongs to the UPF0297 family
IEDFAACK_02639 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IEDFAACK_02640 2.7e-170 yrrI S AI-2E family transporter
IEDFAACK_02641 1.2e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IEDFAACK_02642 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
IEDFAACK_02643 1.8e-108 gluC P ABC transporter
IEDFAACK_02644 7.6e-107 glnP P ABC transporter
IEDFAACK_02645 8e-08 S Protein of unknown function (DUF3918)
IEDFAACK_02646 9.8e-31 yrzR
IEDFAACK_02647 6.6e-81 yrrD S protein conserved in bacteria
IEDFAACK_02648 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IEDFAACK_02649 1.4e-15 S COG0457 FOG TPR repeat
IEDFAACK_02650 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IEDFAACK_02651 4.4e-211 iscS 2.8.1.7 E Cysteine desulfurase
IEDFAACK_02652 1.2e-70 cymR K Transcriptional regulator
IEDFAACK_02653 9.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IEDFAACK_02654 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IEDFAACK_02655 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IEDFAACK_02656 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
IEDFAACK_02658 2.9e-258 lytH 3.5.1.28 M COG3103 SH3 domain protein
IEDFAACK_02659 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IEDFAACK_02660 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEDFAACK_02661 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IEDFAACK_02662 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IEDFAACK_02663 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
IEDFAACK_02664 1.9e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
IEDFAACK_02665 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IEDFAACK_02666 1.6e-48 yrzD S Post-transcriptional regulator
IEDFAACK_02667 8.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEDFAACK_02668 9.2e-113 yrbG S membrane
IEDFAACK_02669 1.5e-59 yrzE S Protein of unknown function (DUF3792)
IEDFAACK_02670 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IEDFAACK_02671 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IEDFAACK_02672 2.6e-18 yrzS S Protein of unknown function (DUF2905)
IEDFAACK_02673 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IEDFAACK_02674 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IEDFAACK_02675 4.8e-93 bofC S BofC C-terminal domain
IEDFAACK_02676 1.7e-251 csbX EGP Major facilitator Superfamily
IEDFAACK_02677 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
IEDFAACK_02678 7.2e-118 yrzF T serine threonine protein kinase
IEDFAACK_02680 2.2e-260 alsT E Sodium alanine symporter
IEDFAACK_02681 3.6e-126 yebC K transcriptional regulatory protein
IEDFAACK_02682 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IEDFAACK_02683 4.8e-157 safA M spore coat assembly protein SafA
IEDFAACK_02684 5.4e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IEDFAACK_02685 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
IEDFAACK_02686 4.1e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
IEDFAACK_02687 1.8e-228 nifS 2.8.1.7 E Cysteine desulfurase
IEDFAACK_02688 3.9e-93 niaR S small molecule binding protein (contains 3H domain)
IEDFAACK_02689 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
IEDFAACK_02690 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
IEDFAACK_02691 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IEDFAACK_02692 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
IEDFAACK_02693 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IEDFAACK_02694 1.2e-55 ysxB J ribosomal protein
IEDFAACK_02695 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IEDFAACK_02696 5.9e-160 spoIVFB S Stage IV sporulation protein
IEDFAACK_02697 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
IEDFAACK_02698 2.5e-144 minD D Belongs to the ParA family
IEDFAACK_02699 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IEDFAACK_02700 1.4e-84 mreD M shape-determining protein
IEDFAACK_02701 1.1e-156 mreC M Involved in formation and maintenance of cell shape
IEDFAACK_02702 1.8e-184 mreB D Rod shape-determining protein MreB
IEDFAACK_02703 1.3e-125 radC E Belongs to the UPF0758 family
IEDFAACK_02704 8.3e-102 maf D septum formation protein Maf
IEDFAACK_02705 7.3e-162 spoIIB S Sporulation related domain
IEDFAACK_02706 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IEDFAACK_02707 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IEDFAACK_02708 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IEDFAACK_02709 1.6e-25
IEDFAACK_02710 2.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IEDFAACK_02711 6.2e-201 spoVID M stage VI sporulation protein D
IEDFAACK_02712 5.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IEDFAACK_02713 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
IEDFAACK_02714 8.4e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IEDFAACK_02715 3.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IEDFAACK_02716 3.6e-146 hemX O cytochrome C
IEDFAACK_02717 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IEDFAACK_02718 1.4e-89 ysxD
IEDFAACK_02719 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
IEDFAACK_02720 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IEDFAACK_02721 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
IEDFAACK_02722 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IEDFAACK_02723 1.6e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IEDFAACK_02724 1.9e-186 ysoA H Tetratricopeptide repeat
IEDFAACK_02725 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IEDFAACK_02726 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IEDFAACK_02727 2.2e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IEDFAACK_02728 7.9e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IEDFAACK_02729 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IEDFAACK_02730 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
IEDFAACK_02731 0.0 ilvB 2.2.1.6 E Acetolactate synthase
IEDFAACK_02732 6.2e-76 ysnE K acetyltransferase
IEDFAACK_02733 1.2e-130 ysnF S protein conserved in bacteria
IEDFAACK_02735 1.5e-91 ysnB S Phosphoesterase
IEDFAACK_02736 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IEDFAACK_02737 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IEDFAACK_02738 5e-196 gerM S COG5401 Spore germination protein
IEDFAACK_02739 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IEDFAACK_02740 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
IEDFAACK_02741 3.3e-30 gerE K Transcriptional regulator
IEDFAACK_02742 5.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
IEDFAACK_02743 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IEDFAACK_02744 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IEDFAACK_02745 2.4e-107 sdhC C succinate dehydrogenase
IEDFAACK_02746 1.2e-79 yslB S Protein of unknown function (DUF2507)
IEDFAACK_02747 1.8e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IEDFAACK_02748 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IEDFAACK_02749 2e-52 trxA O Belongs to the thioredoxin family
IEDFAACK_02750 3.5e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
IEDFAACK_02752 1.5e-175 etfA C Electron transfer flavoprotein
IEDFAACK_02753 4.5e-135 etfB C Electron transfer flavoprotein
IEDFAACK_02754 1.6e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IEDFAACK_02755 1.1e-98 fadR K Transcriptional regulator
IEDFAACK_02756 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IEDFAACK_02757 7.3e-68 yshE S membrane
IEDFAACK_02758 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IEDFAACK_02759 0.0 polX L COG1796 DNA polymerase IV (family X)
IEDFAACK_02760 1.7e-85 cvpA S membrane protein, required for colicin V production
IEDFAACK_02761 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IEDFAACK_02762 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IEDFAACK_02763 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IEDFAACK_02764 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEDFAACK_02765 5.8e-32 sspI S Belongs to the SspI family
IEDFAACK_02766 6.6e-204 ysfB KT regulator
IEDFAACK_02767 2.4e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
IEDFAACK_02768 1.5e-255 glcF C Glycolate oxidase
IEDFAACK_02769 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
IEDFAACK_02770 0.0 cstA T Carbon starvation protein
IEDFAACK_02771 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
IEDFAACK_02772 3.8e-143 araQ G transport system permease
IEDFAACK_02773 1.4e-167 araP G carbohydrate transport
IEDFAACK_02774 4.9e-251 araN G carbohydrate transport
IEDFAACK_02775 5.2e-223 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IEDFAACK_02776 2.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IEDFAACK_02777 2.4e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IEDFAACK_02778 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
IEDFAACK_02779 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IEDFAACK_02780 8.9e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IEDFAACK_02781 3.8e-204 ysdC G COG1363 Cellulase M and related proteins
IEDFAACK_02782 9.2e-68 ysdB S Sigma-w pathway protein YsdB
IEDFAACK_02783 7.5e-45 ysdA S Membrane
IEDFAACK_02784 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IEDFAACK_02785 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IEDFAACK_02786 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IEDFAACK_02788 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IEDFAACK_02789 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IEDFAACK_02790 7e-130 lytT T COG3279 Response regulator of the LytR AlgR family
IEDFAACK_02791 0.0 lytS 2.7.13.3 T Histidine kinase
IEDFAACK_02792 7.3e-149 ysaA S HAD-hyrolase-like
IEDFAACK_02793 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IEDFAACK_02795 1.6e-157 ytxC S YtxC-like family
IEDFAACK_02796 1.1e-107 ytxB S SNARE associated Golgi protein
IEDFAACK_02797 2.5e-172 dnaI L Primosomal protein DnaI
IEDFAACK_02798 2.2e-265 dnaB L Membrane attachment protein
IEDFAACK_02799 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IEDFAACK_02800 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IEDFAACK_02801 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IEDFAACK_02802 4.9e-66 ytcD K Transcriptional regulator
IEDFAACK_02803 4.6e-203 ytbD EGP Major facilitator Superfamily
IEDFAACK_02804 8.9e-161 ytbE S reductase
IEDFAACK_02805 1.3e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IEDFAACK_02806 1.1e-107 ytaF P Probably functions as a manganese efflux pump
IEDFAACK_02807 3.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IEDFAACK_02808 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEDFAACK_02809 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
IEDFAACK_02810 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_02811 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
IEDFAACK_02812 4.1e-242 icd 1.1.1.42 C isocitrate
IEDFAACK_02813 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
IEDFAACK_02814 4.7e-71 yeaL S membrane
IEDFAACK_02815 2.6e-192 ytvI S sporulation integral membrane protein YtvI
IEDFAACK_02816 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
IEDFAACK_02817 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IEDFAACK_02818 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IEDFAACK_02819 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IEDFAACK_02820 2.4e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IEDFAACK_02821 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
IEDFAACK_02822 0.0 dnaE 2.7.7.7 L DNA polymerase
IEDFAACK_02823 3.2e-56 ytrH S Sporulation protein YtrH
IEDFAACK_02824 8.2e-69 ytrI
IEDFAACK_02825 9.2e-29
IEDFAACK_02826 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
IEDFAACK_02827 2.4e-47 ytpI S YtpI-like protein
IEDFAACK_02828 3e-240 ytoI K transcriptional regulator containing CBS domains
IEDFAACK_02829 2.7e-155 ytnM S membrane transporter protein
IEDFAACK_02830 3e-237 ytnL 3.5.1.47 E hydrolase activity
IEDFAACK_02831 2e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
IEDFAACK_02832 2.6e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEDFAACK_02833 7.1e-46 ytnI O COG0695 Glutaredoxin and related proteins
IEDFAACK_02834 4.4e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEDFAACK_02835 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IEDFAACK_02836 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
IEDFAACK_02837 1.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
IEDFAACK_02838 6.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
IEDFAACK_02839 1.8e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
IEDFAACK_02840 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
IEDFAACK_02841 1.9e-172 ytlI K LysR substrate binding domain
IEDFAACK_02842 1.7e-130 ytkL S Belongs to the UPF0173 family
IEDFAACK_02843 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEDFAACK_02845 1.2e-266 argH 4.3.2.1 E argininosuccinate lyase
IEDFAACK_02846 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IEDFAACK_02847 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IEDFAACK_02848 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEDFAACK_02849 2.7e-164 ytxK 2.1.1.72 L DNA methylase
IEDFAACK_02850 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IEDFAACK_02851 8.7e-70 ytfJ S Sporulation protein YtfJ
IEDFAACK_02852 5.6e-116 ytfI S Protein of unknown function (DUF2953)
IEDFAACK_02853 8.5e-87 yteJ S RDD family
IEDFAACK_02854 1.8e-179 sppA OU signal peptide peptidase SppA
IEDFAACK_02855 1.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEDFAACK_02856 0.0 ytcJ S amidohydrolase
IEDFAACK_02857 2.3e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IEDFAACK_02858 2e-29 sspB S spore protein
IEDFAACK_02859 6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IEDFAACK_02860 3.5e-208 iscS2 2.8.1.7 E Cysteine desulfurase
IEDFAACK_02861 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
IEDFAACK_02862 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IEDFAACK_02863 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IEDFAACK_02864 1e-108 yttP K Transcriptional regulator
IEDFAACK_02865 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
IEDFAACK_02866 8.2e-310 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
IEDFAACK_02867 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IEDFAACK_02868 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IEDFAACK_02869 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IEDFAACK_02870 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IEDFAACK_02871 7.9e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
IEDFAACK_02872 6.1e-224 acuC BQ histone deacetylase
IEDFAACK_02873 1.4e-125 motS N Flagellar motor protein
IEDFAACK_02874 7.9e-146 motA N flagellar motor
IEDFAACK_02875 1.7e-182 ccpA K catabolite control protein A
IEDFAACK_02876 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IEDFAACK_02877 1.1e-53 ytxJ O Protein of unknown function (DUF2847)
IEDFAACK_02878 6.6e-17 ytxH S COG4980 Gas vesicle protein
IEDFAACK_02879 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IEDFAACK_02880 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IEDFAACK_02881 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IEDFAACK_02882 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IEDFAACK_02883 9.8e-149 ytpQ S Belongs to the UPF0354 family
IEDFAACK_02884 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IEDFAACK_02885 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
IEDFAACK_02886 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IEDFAACK_02887 2.2e-51 ytzB S small secreted protein
IEDFAACK_02888 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
IEDFAACK_02889 2.4e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
IEDFAACK_02890 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IEDFAACK_02891 2e-45 ytzH S YtzH-like protein
IEDFAACK_02892 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
IEDFAACK_02893 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
IEDFAACK_02894 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IEDFAACK_02895 3.8e-165 ytlQ
IEDFAACK_02896 1.2e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IEDFAACK_02897 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IEDFAACK_02898 1.5e-269 pepV 3.5.1.18 E Dipeptidase
IEDFAACK_02899 7.2e-226 pbuO S permease
IEDFAACK_02900 3.8e-202 ythQ U Bacterial ABC transporter protein EcsB
IEDFAACK_02901 1.3e-131 ythP V ABC transporter
IEDFAACK_02902 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
IEDFAACK_02903 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IEDFAACK_02904 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEDFAACK_02905 2e-230 ytfP S HI0933-like protein
IEDFAACK_02906 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
IEDFAACK_02907 3.1e-26 yteV S Sporulation protein Cse60
IEDFAACK_02908 5.3e-116 yteU S Integral membrane protein
IEDFAACK_02909 1.3e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
IEDFAACK_02910 6.2e-70 yteS G transport
IEDFAACK_02911 5.2e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IEDFAACK_02912 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
IEDFAACK_02913 0.0 ytdP K Transcriptional regulator
IEDFAACK_02914 8.9e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
IEDFAACK_02915 2e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
IEDFAACK_02916 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
IEDFAACK_02917 8.3e-221 bioI 1.14.14.46 C Cytochrome P450
IEDFAACK_02918 1.2e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IEDFAACK_02919 1.7e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IEDFAACK_02920 4.5e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IEDFAACK_02921 2.7e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IEDFAACK_02922 1.5e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IEDFAACK_02923 1.1e-172 ytaP S Acetyl xylan esterase (AXE1)
IEDFAACK_02924 5.6e-189 msmR K Transcriptional regulator
IEDFAACK_02925 7.5e-244 msmE G Bacterial extracellular solute-binding protein
IEDFAACK_02926 6.2e-168 amyD P ABC transporter
IEDFAACK_02927 4.4e-144 amyC P ABC transporter (permease)
IEDFAACK_02928 2.2e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IEDFAACK_02929 2.1e-51 ytwF P Sulfurtransferase
IEDFAACK_02930 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEDFAACK_02931 7.7e-55 ytvB S Protein of unknown function (DUF4257)
IEDFAACK_02932 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IEDFAACK_02933 3.9e-210 yttB EGP Major facilitator Superfamily
IEDFAACK_02934 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
IEDFAACK_02935 0.0 bceB V ABC transporter (permease)
IEDFAACK_02936 7.3e-138 bceA V ABC transporter, ATP-binding protein
IEDFAACK_02937 1.2e-185 T PhoQ Sensor
IEDFAACK_02938 1.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_02939 2.3e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
IEDFAACK_02940 9.1e-127 ytrE V ABC transporter, ATP-binding protein
IEDFAACK_02941 2.6e-148
IEDFAACK_02942 2.8e-86 P ABC-2 family transporter protein
IEDFAACK_02943 2.1e-160 ytrB P abc transporter atp-binding protein
IEDFAACK_02944 5.1e-66 ytrA K GntR family transcriptional regulator
IEDFAACK_02946 6.7e-41 ytzC S Protein of unknown function (DUF2524)
IEDFAACK_02947 8.1e-190 yhcC S Fe-S oxidoreductase
IEDFAACK_02948 9.7e-106 ytqB J Putative rRNA methylase
IEDFAACK_02949 2.8e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
IEDFAACK_02950 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
IEDFAACK_02951 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IEDFAACK_02952 2.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
IEDFAACK_02953 0.0 asnB 6.3.5.4 E Asparagine synthase
IEDFAACK_02954 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IEDFAACK_02955 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IEDFAACK_02956 1.2e-38 ytmB S Protein of unknown function (DUF2584)
IEDFAACK_02957 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IEDFAACK_02958 8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IEDFAACK_02959 1.4e-144 ytlC P ABC transporter
IEDFAACK_02960 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IEDFAACK_02961 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
IEDFAACK_02962 7.8e-62 ytkC S Bacteriophage holin family
IEDFAACK_02963 2.1e-76 dps P Belongs to the Dps family
IEDFAACK_02965 2.4e-72 ytkA S YtkA-like
IEDFAACK_02966 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IEDFAACK_02967 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IEDFAACK_02968 6.1e-41 rpmE2 J Ribosomal protein L31
IEDFAACK_02969 4e-248 cydA 1.10.3.14 C oxidase, subunit
IEDFAACK_02970 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IEDFAACK_02971 1.1e-24 S Domain of Unknown Function (DUF1540)
IEDFAACK_02972 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IEDFAACK_02973 1.1e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IEDFAACK_02974 7.3e-138 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IEDFAACK_02975 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
IEDFAACK_02976 9.2e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IEDFAACK_02977 1e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IEDFAACK_02978 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IEDFAACK_02979 1e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IEDFAACK_02980 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IEDFAACK_02981 2.7e-271 menF 5.4.4.2 HQ Isochorismate synthase
IEDFAACK_02982 2.6e-132 dksA T COG1734 DnaK suppressor protein
IEDFAACK_02983 4.3e-152 galU 2.7.7.9 M Nucleotidyl transferase
IEDFAACK_02984 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IEDFAACK_02985 1.7e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
IEDFAACK_02986 1.8e-231 ytcC M Glycosyltransferase Family 4
IEDFAACK_02988 5.1e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
IEDFAACK_02989 3.1e-217 cotSA M Glycosyl transferases group 1
IEDFAACK_02990 3.1e-203 cotI S Spore coat protein
IEDFAACK_02991 1.4e-75 tspO T membrane
IEDFAACK_02992 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IEDFAACK_02993 1.1e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
IEDFAACK_02994 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
IEDFAACK_02995 8.9e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IEDFAACK_02996 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IEDFAACK_03005 7.8e-08
IEDFAACK_03006 1.3e-09
IEDFAACK_03013 2e-08
IEDFAACK_03018 3.4e-39 S COG NOG14552 non supervised orthologous group
IEDFAACK_03019 1.3e-89 thiT S Thiamine transporter protein (Thia_YuaJ)
IEDFAACK_03020 2.4e-92 M1-753 M FR47-like protein
IEDFAACK_03021 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
IEDFAACK_03022 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
IEDFAACK_03023 3.9e-84 yuaE S DinB superfamily
IEDFAACK_03024 7.4e-106 yuaD
IEDFAACK_03025 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
IEDFAACK_03026 5.2e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
IEDFAACK_03027 1.9e-92 yuaC K Belongs to the GbsR family
IEDFAACK_03028 2.2e-91 yuaB
IEDFAACK_03029 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
IEDFAACK_03030 1.3e-235 ktrB P Potassium
IEDFAACK_03031 1e-38 yiaA S yiaA/B two helix domain
IEDFAACK_03032 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IEDFAACK_03033 7.5e-275 yubD P Major Facilitator Superfamily
IEDFAACK_03034 2.2e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
IEDFAACK_03036 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IEDFAACK_03037 3.7e-189 yubA S transporter activity
IEDFAACK_03038 3.7e-182 ygjR S Oxidoreductase
IEDFAACK_03039 1.1e-250 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
IEDFAACK_03040 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
IEDFAACK_03041 2.7e-274 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IEDFAACK_03042 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
IEDFAACK_03043 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
IEDFAACK_03044 7.3e-238 mcpA NT chemotaxis protein
IEDFAACK_03045 3.2e-294 mcpA NT chemotaxis protein
IEDFAACK_03046 1.1e-220 mcpA NT chemotaxis protein
IEDFAACK_03047 1.3e-223 mcpA NT chemotaxis protein
IEDFAACK_03048 3.8e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
IEDFAACK_03049 1e-35
IEDFAACK_03050 3.1e-71 yugU S Uncharacterised protein family UPF0047
IEDFAACK_03051 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
IEDFAACK_03052 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
IEDFAACK_03053 1.4e-116 yugP S Zn-dependent protease
IEDFAACK_03054 2.3e-38
IEDFAACK_03055 1.1e-53 mstX S Membrane-integrating protein Mistic
IEDFAACK_03056 1.1e-181 yugO P COG1226 Kef-type K transport systems
IEDFAACK_03057 1.3e-72 yugN S YugN-like family
IEDFAACK_03059 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
IEDFAACK_03060 5.3e-228 yugK C Dehydrogenase
IEDFAACK_03061 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
IEDFAACK_03062 1.1e-34 yuzA S Domain of unknown function (DUF378)
IEDFAACK_03063 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
IEDFAACK_03064 2.1e-199 yugH 2.6.1.1 E Aminotransferase
IEDFAACK_03065 1.6e-85 alaR K Transcriptional regulator
IEDFAACK_03066 2.2e-156 yugF I Hydrolase
IEDFAACK_03067 1.1e-40 yugE S Domain of unknown function (DUF1871)
IEDFAACK_03068 4.4e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IEDFAACK_03069 3e-232 T PhoQ Sensor
IEDFAACK_03070 7.4e-70 kapB G Kinase associated protein B
IEDFAACK_03071 4.6e-114 kapD L the KinA pathway to sporulation
IEDFAACK_03073 1.9e-184 yuxJ EGP Major facilitator Superfamily
IEDFAACK_03074 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
IEDFAACK_03075 5.3e-74 yuxK S protein conserved in bacteria
IEDFAACK_03076 6.3e-78 yufK S Family of unknown function (DUF5366)
IEDFAACK_03077 4.9e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IEDFAACK_03078 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
IEDFAACK_03079 6.4e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IEDFAACK_03080 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IEDFAACK_03081 3.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
IEDFAACK_03082 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
IEDFAACK_03083 4.1e-232 maeN C COG3493 Na citrate symporter
IEDFAACK_03084 5e-15
IEDFAACK_03085 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IEDFAACK_03086 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IEDFAACK_03087 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IEDFAACK_03088 7.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IEDFAACK_03089 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IEDFAACK_03090 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IEDFAACK_03091 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
IEDFAACK_03092 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
IEDFAACK_03093 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEDFAACK_03094 0.0 comP 2.7.13.3 T Histidine kinase
IEDFAACK_03096 1.1e-149 comQ H Polyprenyl synthetase
IEDFAACK_03098 3.8e-23 yuzC
IEDFAACK_03099 5.4e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
IEDFAACK_03100 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IEDFAACK_03101 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
IEDFAACK_03102 5.1e-66 yueI S Protein of unknown function (DUF1694)
IEDFAACK_03103 1.3e-38 yueH S YueH-like protein
IEDFAACK_03104 6.6e-31 yueG S Spore germination protein gerPA/gerPF
IEDFAACK_03105 3.2e-190 yueF S transporter activity
IEDFAACK_03106 1.2e-70 S Protein of unknown function (DUF2283)
IEDFAACK_03107 2.9e-24 S Protein of unknown function (DUF2642)
IEDFAACK_03108 4.8e-96 yueE S phosphohydrolase
IEDFAACK_03109 1.9e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEDFAACK_03110 3.3e-64 yueC S Family of unknown function (DUF5383)
IEDFAACK_03111 4e-168 esaA S type VII secretion protein EsaA
IEDFAACK_03112 3.5e-133 esaA S type VII secretion protein EsaA
IEDFAACK_03113 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IEDFAACK_03114 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
IEDFAACK_03115 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
IEDFAACK_03116 2.8e-45 esxA S Belongs to the WXG100 family
IEDFAACK_03117 6.1e-227 yukF QT Transcriptional regulator
IEDFAACK_03118 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
IEDFAACK_03119 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
IEDFAACK_03120 1.1e-35 mbtH S MbtH-like protein
IEDFAACK_03121 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_03122 9.3e-175 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
IEDFAACK_03123 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
IEDFAACK_03124 5.6e-225 entC 5.4.4.2 HQ Isochorismate synthase
IEDFAACK_03125 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFAACK_03126 3.9e-167 besA S Putative esterase
IEDFAACK_03127 1.3e-121 yuiH S Oxidoreductase molybdopterin binding domain
IEDFAACK_03128 1.1e-93 bioY S Biotin biosynthesis protein
IEDFAACK_03129 3.9e-211 yuiF S antiporter
IEDFAACK_03130 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IEDFAACK_03131 2e-77 yuiD S protein conserved in bacteria
IEDFAACK_03132 4.7e-117 yuiC S protein conserved in bacteria
IEDFAACK_03133 8.4e-27 yuiB S Putative membrane protein
IEDFAACK_03134 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
IEDFAACK_03135 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
IEDFAACK_03137 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IEDFAACK_03138 2.5e-115 paiB K Putative FMN-binding domain
IEDFAACK_03139 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEDFAACK_03140 3.7e-63 erpA S Belongs to the HesB IscA family
IEDFAACK_03141 1.1e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IEDFAACK_03142 4.5e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IEDFAACK_03143 3.2e-39 yuzB S Belongs to the UPF0349 family
IEDFAACK_03144 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
IEDFAACK_03145 1.1e-55 yuzD S protein conserved in bacteria
IEDFAACK_03146 3.7e-57 yutI O COG0694 Thioredoxin-like proteins and domains
IEDFAACK_03147 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
IEDFAACK_03148 1.9e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IEDFAACK_03149 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IEDFAACK_03150 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
IEDFAACK_03151 5.9e-199 yutH S Spore coat protein
IEDFAACK_03152 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
IEDFAACK_03153 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IEDFAACK_03154 3.6e-73 yutE S Protein of unknown function DUF86
IEDFAACK_03155 9.7e-48 yutD S protein conserved in bacteria
IEDFAACK_03156 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IEDFAACK_03157 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IEDFAACK_03158 1.3e-195 lytH M Peptidase, M23
IEDFAACK_03159 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
IEDFAACK_03160 5.3e-47 yunC S Domain of unknown function (DUF1805)
IEDFAACK_03161 1.1e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IEDFAACK_03162 3.8e-140 yunE S membrane transporter protein
IEDFAACK_03163 4.8e-170 yunF S Protein of unknown function DUF72
IEDFAACK_03164 3.1e-59 yunG
IEDFAACK_03165 1.8e-256 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IEDFAACK_03166 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
IEDFAACK_03167 5.1e-227 pbuX F Permease family
IEDFAACK_03168 7.4e-223 pbuX F xanthine
IEDFAACK_03169 3.5e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IEDFAACK_03170 3.8e-57 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IEDFAACK_03173 2.8e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IEDFAACK_03174 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IEDFAACK_03175 5.2e-145 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IEDFAACK_03176 3.8e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
IEDFAACK_03177 3e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IEDFAACK_03179 1.2e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IEDFAACK_03180 1.4e-231 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IEDFAACK_03181 1.2e-168 bsn L Ribonuclease
IEDFAACK_03182 5.9e-205 msmX P Belongs to the ABC transporter superfamily
IEDFAACK_03183 1.6e-134 yurK K UTRA
IEDFAACK_03184 8.2e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
IEDFAACK_03185 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
IEDFAACK_03186 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
IEDFAACK_03187 3.2e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
IEDFAACK_03188 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IEDFAACK_03189 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
IEDFAACK_03190 1.9e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
IEDFAACK_03192 1e-41
IEDFAACK_03193 3.5e-64 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEDFAACK_03194 3.5e-271 sufB O FeS cluster assembly
IEDFAACK_03195 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
IEDFAACK_03196 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IEDFAACK_03197 1.8e-245 sufD O assembly protein SufD
IEDFAACK_03198 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IEDFAACK_03199 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEDFAACK_03200 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
IEDFAACK_03201 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
IEDFAACK_03202 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEDFAACK_03203 2.1e-55 yusD S SCP-2 sterol transfer family
IEDFAACK_03204 1.2e-54 traF CO Thioredoxin
IEDFAACK_03205 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
IEDFAACK_03206 1.1e-39 yusG S Protein of unknown function (DUF2553)
IEDFAACK_03207 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IEDFAACK_03208 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
IEDFAACK_03209 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
IEDFAACK_03210 1.1e-214 fadA 2.3.1.16 I Belongs to the thiolase family
IEDFAACK_03211 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
IEDFAACK_03212 8.1e-09 S YuzL-like protein
IEDFAACK_03213 1.9e-164 fadM E Proline dehydrogenase
IEDFAACK_03214 5.1e-40
IEDFAACK_03215 5.4e-53 yusN M Coat F domain
IEDFAACK_03216 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
IEDFAACK_03217 1.2e-291 yusP P Major facilitator superfamily
IEDFAACK_03218 2.1e-64 yusQ S Tautomerase enzyme
IEDFAACK_03219 5.5e-106 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFAACK_03220 5.7e-158 yusT K LysR substrate binding domain
IEDFAACK_03221 1.5e-46 yusU S Protein of unknown function (DUF2573)
IEDFAACK_03222 1e-153 yusV 3.6.3.34 HP ABC transporter
IEDFAACK_03223 1.9e-66 S YusW-like protein
IEDFAACK_03224 4.2e-301 pepF2 E COG1164 Oligoendopeptidase F
IEDFAACK_03225 5.8e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFAACK_03226 2.7e-79 dps P Ferritin-like domain
IEDFAACK_03227 1.8e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEDFAACK_03228 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_03229 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
IEDFAACK_03230 1.3e-157 yuxN K Transcriptional regulator
IEDFAACK_03231 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IEDFAACK_03232 3.9e-24 S Protein of unknown function (DUF3970)
IEDFAACK_03233 1.2e-245 gerAA EG Spore germination protein
IEDFAACK_03234 1.5e-195 gerAB E Spore germination protein
IEDFAACK_03235 4.1e-185 gerAC S Spore germination B3/ GerAC like, C-terminal
IEDFAACK_03236 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEDFAACK_03237 7.9e-186 vraS 2.7.13.3 T Histidine kinase
IEDFAACK_03238 3e-125 yvqF S Cell wall-active antibiotics response 4TMS YvqF
IEDFAACK_03239 1.2e-120 liaG S Putative adhesin
IEDFAACK_03240 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IEDFAACK_03241 6.2e-61 liaI S membrane
IEDFAACK_03242 4.8e-227 yvqJ EGP Major facilitator Superfamily
IEDFAACK_03243 6.1e-100 yvqK 2.5.1.17 S Adenosyltransferase
IEDFAACK_03244 4.9e-246 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IEDFAACK_03245 1.7e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_03246 3.5e-166 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IEDFAACK_03247 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFAACK_03248 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
IEDFAACK_03249 0.0 T PhoQ Sensor
IEDFAACK_03250 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_03251 7.2e-23
IEDFAACK_03252 9.5e-98 yvrI K RNA polymerase
IEDFAACK_03253 2.4e-19 S YvrJ protein family
IEDFAACK_03254 3.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
IEDFAACK_03255 1.3e-64 yvrL S Regulatory protein YrvL
IEDFAACK_03256 1.2e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
IEDFAACK_03257 2.1e-123 macB V ABC transporter, ATP-binding protein
IEDFAACK_03258 2e-174 M Efflux transporter rnd family, mfp subunit
IEDFAACK_03259 3.7e-148 fhuC 3.6.3.34 HP ABC transporter
IEDFAACK_03260 2.9e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_03261 7.9e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEDFAACK_03262 1e-176 fhuD P ABC transporter
IEDFAACK_03264 4.9e-236 yvsH E Arginine ornithine antiporter
IEDFAACK_03265 6.5e-16 S Small spore protein J (Spore_SspJ)
IEDFAACK_03266 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
IEDFAACK_03267 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IEDFAACK_03268 3.3e-164 yvgK P COG1910 Periplasmic molybdate-binding protein domain
IEDFAACK_03269 4.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
IEDFAACK_03270 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
IEDFAACK_03271 2.5e-155 yvgN S reductase
IEDFAACK_03272 5.4e-86 yvgO
IEDFAACK_03273 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
IEDFAACK_03274 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IEDFAACK_03275 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IEDFAACK_03276 0.0 helD 3.6.4.12 L DNA helicase
IEDFAACK_03277 8.6e-102 yvgT S membrane
IEDFAACK_03278 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
IEDFAACK_03279 3.9e-103 bdbD O Thioredoxin
IEDFAACK_03280 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IEDFAACK_03281 0.0 copA 3.6.3.54 P P-type ATPase
IEDFAACK_03282 1.5e-29 copZ P Copper resistance protein CopZ
IEDFAACK_03283 2.2e-48 csoR S transcriptional
IEDFAACK_03284 9.9e-194 yvaA 1.1.1.371 S Oxidoreductase
IEDFAACK_03285 1.2e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEDFAACK_03286 0.0 yvaC S Fusaric acid resistance protein-like
IEDFAACK_03287 1.3e-72 yvaD S Family of unknown function (DUF5360)
IEDFAACK_03288 2.4e-54 yvaE P Small Multidrug Resistance protein
IEDFAACK_03289 3e-96 K Bacterial regulatory proteins, tetR family
IEDFAACK_03290 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFAACK_03292 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IEDFAACK_03293 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IEDFAACK_03294 5.6e-143 est 3.1.1.1 S Carboxylesterase
IEDFAACK_03295 2.4e-23 secG U Preprotein translocase subunit SecG
IEDFAACK_03296 1.8e-152 yvaM S Serine aminopeptidase, S33
IEDFAACK_03297 7.5e-36 yvzC K Transcriptional
IEDFAACK_03298 4e-69 K transcriptional
IEDFAACK_03299 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
IEDFAACK_03300 1.4e-53 yodB K transcriptional
IEDFAACK_03301 6.7e-100 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IEDFAACK_03302 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IEDFAACK_03303 4.7e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IEDFAACK_03304 1.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IEDFAACK_03305 1.9e-60 yvbF K Belongs to the GbsR family
IEDFAACK_03306 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IEDFAACK_03307 1.8e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IEDFAACK_03308 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IEDFAACK_03309 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IEDFAACK_03310 3.5e-97 yvbF K Belongs to the GbsR family
IEDFAACK_03311 2.3e-100 yvbG U UPF0056 membrane protein
IEDFAACK_03312 8.6e-113 yvbH S YvbH-like oligomerisation region
IEDFAACK_03313 4e-122 exoY M Membrane
IEDFAACK_03314 0.0 tcaA S response to antibiotic
IEDFAACK_03315 1.6e-241 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IEDFAACK_03316 2.2e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
IEDFAACK_03317 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IEDFAACK_03318 8.5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IEDFAACK_03319 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IEDFAACK_03320 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IEDFAACK_03321 1.6e-252 araE EGP Major facilitator Superfamily
IEDFAACK_03322 5.5e-203 araR K transcriptional
IEDFAACK_03323 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEDFAACK_03324 3.9e-159 yvbU K Transcriptional regulator
IEDFAACK_03325 9.4e-156 yvbV EG EamA-like transporter family
IEDFAACK_03326 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
IEDFAACK_03327 5.4e-192 yvbX S Glycosyl hydrolase
IEDFAACK_03328 4.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IEDFAACK_03329 4.6e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IEDFAACK_03330 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IEDFAACK_03331 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEDFAACK_03332 2.1e-197 desK 2.7.13.3 T Histidine kinase
IEDFAACK_03333 5.8e-75 yvfS V COG0842 ABC-type multidrug transport system, permease component
IEDFAACK_03334 2e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
IEDFAACK_03335 1.8e-155 rsbQ S Alpha/beta hydrolase family
IEDFAACK_03336 3.5e-198 rsbU 3.1.3.3 T response regulator
IEDFAACK_03337 1.1e-250 galA 3.2.1.89 G arabinogalactan
IEDFAACK_03338 0.0 lacA 3.2.1.23 G beta-galactosidase
IEDFAACK_03339 7.2e-150 ganQ P transport
IEDFAACK_03340 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
IEDFAACK_03341 1.1e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
IEDFAACK_03342 1.8e-184 lacR K Transcriptional regulator
IEDFAACK_03343 1e-112 yvfI K COG2186 Transcriptional regulators
IEDFAACK_03344 2.6e-308 yvfH C L-lactate permease
IEDFAACK_03345 1.4e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IEDFAACK_03346 1e-31 yvfG S YvfG protein
IEDFAACK_03347 1.7e-187 yvfF GM Exopolysaccharide biosynthesis protein
IEDFAACK_03348 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IEDFAACK_03349 2.4e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
IEDFAACK_03350 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IEDFAACK_03351 1.7e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEDFAACK_03352 5.6e-189 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
IEDFAACK_03353 4e-206 epsI GM pyruvyl transferase
IEDFAACK_03354 2.2e-193 epsH GT2 S Glycosyltransferase like family 2
IEDFAACK_03355 1.1e-206 epsG S EpsG family
IEDFAACK_03356 1.4e-217 epsF GT4 M Glycosyl transferases group 1
IEDFAACK_03357 2.7e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IEDFAACK_03358 4.8e-218 epsD GT4 M Glycosyl transferase 4-like
IEDFAACK_03359 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
IEDFAACK_03360 3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
IEDFAACK_03361 4e-122 ywqC M biosynthesis protein
IEDFAACK_03362 6.3e-76 slr K transcriptional
IEDFAACK_03363 7.5e-280 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
IEDFAACK_03364 1.7e-92 padC Q Phenolic acid decarboxylase
IEDFAACK_03365 5.8e-74 MA20_18690 S Protein of unknown function (DUF3237)
IEDFAACK_03366 1.7e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IEDFAACK_03367 6.7e-259 pbpE V Beta-lactamase
IEDFAACK_03368 1.7e-273 sacB 2.4.1.10 GH68 M levansucrase activity
IEDFAACK_03369 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
IEDFAACK_03370 2.3e-295 yveA E amino acid
IEDFAACK_03371 7.4e-106 yvdT K Transcriptional regulator
IEDFAACK_03372 4.3e-50 ykkC P Small Multidrug Resistance protein
IEDFAACK_03373 4.1e-50 sugE P Small Multidrug Resistance protein
IEDFAACK_03374 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
IEDFAACK_03376 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IEDFAACK_03377 1.3e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
IEDFAACK_03378 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
IEDFAACK_03379 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
IEDFAACK_03380 6.3e-157 malA S Protein of unknown function (DUF1189)
IEDFAACK_03381 5.6e-147 malD P transport
IEDFAACK_03382 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
IEDFAACK_03383 1.1e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
IEDFAACK_03384 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
IEDFAACK_03385 3.6e-174 yvdE K Transcriptional regulator
IEDFAACK_03386 1.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
IEDFAACK_03387 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
IEDFAACK_03388 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
IEDFAACK_03389 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IEDFAACK_03390 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEDFAACK_03391 0.0 yxdM V ABC transporter (permease)
IEDFAACK_03392 5.6e-141 yvcR V ABC transporter, ATP-binding protein
IEDFAACK_03393 5.8e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
IEDFAACK_03394 9.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_03395 3.3e-32
IEDFAACK_03396 1.9e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
IEDFAACK_03397 1.6e-36 crh G Phosphocarrier protein Chr
IEDFAACK_03398 1.4e-170 whiA K May be required for sporulation
IEDFAACK_03399 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IEDFAACK_03400 5.7e-166 rapZ S Displays ATPase and GTPase activities
IEDFAACK_03401 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IEDFAACK_03402 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IEDFAACK_03403 1.9e-99 usp CBM50 M protein conserved in bacteria
IEDFAACK_03404 6.5e-276 S COG0457 FOG TPR repeat
IEDFAACK_03405 0.0 msbA2 3.6.3.44 V ABC transporter
IEDFAACK_03407 1.5e-233
IEDFAACK_03408 2.2e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
IEDFAACK_03409 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IEDFAACK_03410 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IEDFAACK_03411 2.2e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IEDFAACK_03412 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IEDFAACK_03413 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IEDFAACK_03414 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IEDFAACK_03415 2.9e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IEDFAACK_03416 4.5e-140 yvpB NU protein conserved in bacteria
IEDFAACK_03417 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
IEDFAACK_03418 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
IEDFAACK_03419 1.9e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IEDFAACK_03420 1.1e-159 yvoD P COG0370 Fe2 transport system protein B
IEDFAACK_03421 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IEDFAACK_03422 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IEDFAACK_03423 2.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IEDFAACK_03424 3.3e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IEDFAACK_03425 8.9e-133 yvoA K transcriptional
IEDFAACK_03426 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
IEDFAACK_03427 1.2e-50 yvlD S Membrane
IEDFAACK_03428 2.6e-26 pspB KT PspC domain
IEDFAACK_03429 9.2e-166 yvlB S Putative adhesin
IEDFAACK_03430 8e-49 yvlA
IEDFAACK_03431 5.7e-33 yvkN
IEDFAACK_03432 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IEDFAACK_03433 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IEDFAACK_03434 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IEDFAACK_03435 1.2e-30 csbA S protein conserved in bacteria
IEDFAACK_03436 0.0 yvkC 2.7.9.2 GT Phosphotransferase
IEDFAACK_03437 1e-99 yvkB K Transcriptional regulator
IEDFAACK_03438 3.3e-226 yvkA EGP Major facilitator Superfamily
IEDFAACK_03439 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEDFAACK_03440 5.3e-56 swrA S Swarming motility protein
IEDFAACK_03441 2.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
IEDFAACK_03442 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IEDFAACK_03443 2.7e-123 ftsE D cell division ATP-binding protein FtsE
IEDFAACK_03444 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
IEDFAACK_03445 3.5e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
IEDFAACK_03446 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IEDFAACK_03447 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IEDFAACK_03448 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IEDFAACK_03449 4.6e-51
IEDFAACK_03450 1.9e-08 fliT S bacterial-type flagellum organization
IEDFAACK_03451 6.5e-69 fliS N flagellar protein FliS
IEDFAACK_03452 7.5e-237 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IEDFAACK_03453 1.2e-55 flaG N flagellar protein FlaG
IEDFAACK_03454 9.6e-74 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IEDFAACK_03455 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IEDFAACK_03456 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IEDFAACK_03457 5.7e-50 yviE
IEDFAACK_03458 7.8e-155 flgL N Belongs to the bacterial flagellin family
IEDFAACK_03459 1.2e-264 flgK N flagellar hook-associated protein
IEDFAACK_03460 4.1e-78 flgN NOU FlgN protein
IEDFAACK_03461 8e-39 flgM KNU Negative regulator of flagellin synthesis
IEDFAACK_03462 7e-74 yvyF S flagellar protein
IEDFAACK_03463 2.6e-80 comFC S Phosphoribosyl transferase domain
IEDFAACK_03464 3.7e-45 comFB S Late competence development protein ComFB
IEDFAACK_03465 6.9e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IEDFAACK_03466 6.2e-154 degV S protein conserved in bacteria
IEDFAACK_03467 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEDFAACK_03468 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IEDFAACK_03469 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
IEDFAACK_03470 6e-163 yvhJ K Transcriptional regulator
IEDFAACK_03471 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IEDFAACK_03472 1.2e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
IEDFAACK_03473 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
IEDFAACK_03474 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
IEDFAACK_03475 1.6e-261 tuaE M Teichuronic acid biosynthesis protein
IEDFAACK_03476 9.9e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IEDFAACK_03477 2.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
IEDFAACK_03478 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEDFAACK_03479 3.1e-74 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IEDFAACK_03480 1.9e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IEDFAACK_03481 6.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IEDFAACK_03482 1.9e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IEDFAACK_03483 3.3e-55 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IEDFAACK_03484 1.1e-273 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IEDFAACK_03485 2.3e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IEDFAACK_03486 2.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
IEDFAACK_03487 5.7e-264 gerBA EG Spore germination protein
IEDFAACK_03488 8.1e-194 gerBB E Spore germination protein
IEDFAACK_03489 5.8e-208 gerAC S Spore germination protein
IEDFAACK_03490 7.8e-247 ywtG EGP Major facilitator Superfamily
IEDFAACK_03491 2.4e-170 ywtF K Transcriptional regulator
IEDFAACK_03492 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
IEDFAACK_03493 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IEDFAACK_03494 3.6e-21 ywtC
IEDFAACK_03495 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IEDFAACK_03496 8.6e-70 pgsC S biosynthesis protein
IEDFAACK_03497 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
IEDFAACK_03498 5.5e-178 rbsR K transcriptional
IEDFAACK_03499 4.2e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEDFAACK_03500 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IEDFAACK_03501 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IEDFAACK_03502 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
IEDFAACK_03503 8.2e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
IEDFAACK_03504 7.3e-92 batE T Sh3 type 3 domain protein
IEDFAACK_03505 8e-48 ywsA S Protein of unknown function (DUF3892)
IEDFAACK_03506 2.8e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
IEDFAACK_03507 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
IEDFAACK_03508 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IEDFAACK_03509 1.1e-169 alsR K LysR substrate binding domain
IEDFAACK_03510 1.8e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IEDFAACK_03511 1.1e-124 ywrJ
IEDFAACK_03512 2.6e-125 cotB
IEDFAACK_03513 6.2e-207 cotH M Spore Coat
IEDFAACK_03514 1.3e-12
IEDFAACK_03515 1.5e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEDFAACK_03516 2.5e-53 S Domain of unknown function (DUF4181)
IEDFAACK_03517 2.2e-309 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IEDFAACK_03518 8e-82 ywrC K Transcriptional regulator
IEDFAACK_03519 2.7e-103 ywrB P Chromate transporter
IEDFAACK_03520 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
IEDFAACK_03522 3.5e-97 ywqN S NAD(P)H-dependent
IEDFAACK_03523 1.9e-161 K Transcriptional regulator
IEDFAACK_03524 1e-125 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IEDFAACK_03525 1.8e-215 ywqJ L nucleic acid phosphodiester bond hydrolysis
IEDFAACK_03526 3.9e-38 ywqI S Family of unknown function (DUF5344)
IEDFAACK_03527 1.1e-13 S Domain of unknown function (DUF5082)
IEDFAACK_03528 1.3e-153 ywqG S Domain of unknown function (DUF1963)
IEDFAACK_03529 1.8e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IEDFAACK_03530 3.3e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
IEDFAACK_03531 8.4e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
IEDFAACK_03532 2e-116 ywqC M biosynthesis protein
IEDFAACK_03533 1.2e-17
IEDFAACK_03534 2.7e-307 ywqB S SWIM zinc finger
IEDFAACK_03535 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IEDFAACK_03536 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
IEDFAACK_03537 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
IEDFAACK_03538 3.7e-57 ssbB L Single-stranded DNA-binding protein
IEDFAACK_03539 3.8e-66 ywpG
IEDFAACK_03540 1.1e-66 ywpF S YwpF-like protein
IEDFAACK_03541 2e-53 srtA 3.4.22.70 M Sortase family
IEDFAACK_03542 6.4e-146 ywpD T Histidine kinase
IEDFAACK_03543 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IEDFAACK_03544 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IEDFAACK_03545 5.7e-197 S aspartate phosphatase
IEDFAACK_03546 8.3e-140 flhP N flagellar basal body
IEDFAACK_03547 5.8e-125 flhO N flagellar basal body
IEDFAACK_03548 3.5e-180 mbl D Rod shape-determining protein
IEDFAACK_03549 3e-44 spoIIID K Stage III sporulation protein D
IEDFAACK_03550 2.1e-70 ywoH K COG1846 Transcriptional regulators
IEDFAACK_03551 1.7e-210 ywoG EGP Major facilitator Superfamily
IEDFAACK_03552 2.3e-225 ywoF P Right handed beta helix region
IEDFAACK_03553 2.8e-279 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
IEDFAACK_03554 9.1e-240 ywoD EGP Major facilitator superfamily
IEDFAACK_03555 6.8e-104 phzA Q Isochorismatase family
IEDFAACK_03556 1.2e-77
IEDFAACK_03557 3.3e-225 amt P Ammonium transporter
IEDFAACK_03558 1.6e-58 nrgB K Belongs to the P(II) protein family
IEDFAACK_03559 1.3e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
IEDFAACK_03560 5.6e-71 ywnJ S VanZ like family
IEDFAACK_03561 4.1e-121 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
IEDFAACK_03562 2.7e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
IEDFAACK_03563 3.4e-09 ywnC S Family of unknown function (DUF5362)
IEDFAACK_03564 2.9e-70 ywnF S Family of unknown function (DUF5392)
IEDFAACK_03565 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEDFAACK_03566 2.2e-142 mta K transcriptional
IEDFAACK_03567 1.7e-58 ywnC S Family of unknown function (DUF5362)
IEDFAACK_03568 1.1e-113 ywnB S NAD(P)H-binding
IEDFAACK_03569 1.7e-64 ywnA K Transcriptional regulator
IEDFAACK_03570 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IEDFAACK_03571 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IEDFAACK_03572 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IEDFAACK_03574 3.8e-11 csbD K CsbD-like
IEDFAACK_03575 3e-84 ywmF S Peptidase M50
IEDFAACK_03576 1.3e-103 S response regulator aspartate phosphatase
IEDFAACK_03577 5.9e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IEDFAACK_03578 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IEDFAACK_03580 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
IEDFAACK_03581 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
IEDFAACK_03582 1.2e-175 spoIID D Stage II sporulation protein D
IEDFAACK_03583 3.9e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEDFAACK_03584 8.2e-134 ywmB S TATA-box binding
IEDFAACK_03585 2.8e-32 ywzB S membrane
IEDFAACK_03586 4.1e-86 ywmA
IEDFAACK_03587 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IEDFAACK_03588 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IEDFAACK_03589 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IEDFAACK_03590 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IEDFAACK_03591 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEDFAACK_03592 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IEDFAACK_03593 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEDFAACK_03594 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
IEDFAACK_03595 7.4e-62 atpI S ATP synthase
IEDFAACK_03596 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IEDFAACK_03597 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IEDFAACK_03598 7.2e-95 ywlG S Belongs to the UPF0340 family
IEDFAACK_03599 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
IEDFAACK_03600 3.6e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEDFAACK_03601 1.7e-91 mntP P Probably functions as a manganese efflux pump
IEDFAACK_03602 1.8e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IEDFAACK_03603 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
IEDFAACK_03604 6.1e-112 spoIIR S stage II sporulation protein R
IEDFAACK_03605 2.2e-55 ywlA S Uncharacterised protein family (UPF0715)
IEDFAACK_03607 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IEDFAACK_03608 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IEDFAACK_03609 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEDFAACK_03610 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IEDFAACK_03611 8.6e-160 ywkB S Membrane transport protein
IEDFAACK_03612 0.0 sfcA 1.1.1.38 C malic enzyme
IEDFAACK_03613 1.2e-103 tdk 2.7.1.21 F thymidine kinase
IEDFAACK_03614 1.1e-32 rpmE J Binds the 23S rRNA
IEDFAACK_03615 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IEDFAACK_03616 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
IEDFAACK_03617 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEDFAACK_03618 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IEDFAACK_03619 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
IEDFAACK_03620 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
IEDFAACK_03621 1.8e-90 ywjG S Domain of unknown function (DUF2529)
IEDFAACK_03622 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IEDFAACK_03623 5.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IEDFAACK_03624 7e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
IEDFAACK_03625 0.0 fadF C COG0247 Fe-S oxidoreductase
IEDFAACK_03626 2.9e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IEDFAACK_03627 3.6e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IEDFAACK_03628 6e-42 ywjC
IEDFAACK_03629 2.5e-92 ywjB H RibD C-terminal domain
IEDFAACK_03630 0.0 ywjA V ABC transporter
IEDFAACK_03631 1.9e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEDFAACK_03632 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
IEDFAACK_03633 3.6e-94 narJ 1.7.5.1 C nitrate reductase
IEDFAACK_03634 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
IEDFAACK_03635 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IEDFAACK_03636 7e-86 arfM T cyclic nucleotide binding
IEDFAACK_03637 1.7e-139 ywiC S YwiC-like protein
IEDFAACK_03638 5.9e-129 fnr K helix_turn_helix, cAMP Regulatory protein
IEDFAACK_03639 2.3e-213 narK P COG2223 Nitrate nitrite transporter
IEDFAACK_03640 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IEDFAACK_03641 4.7e-73 ywiB S protein conserved in bacteria
IEDFAACK_03642 1e-07 S Bacteriocin subtilosin A
IEDFAACK_03643 6.4e-270 C Fe-S oxidoreductases
IEDFAACK_03645 3.3e-132 cbiO V ABC transporter
IEDFAACK_03646 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
IEDFAACK_03647 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
IEDFAACK_03648 4.5e-249 L Peptidase, M16
IEDFAACK_03650 6.8e-243 ywhL CO amine dehydrogenase activity
IEDFAACK_03651 1.1e-189 ywhK CO amine dehydrogenase activity
IEDFAACK_03652 3.1e-79 S aspartate phosphatase
IEDFAACK_03654 1.6e-26 ywhH S Aminoacyl-tRNA editing domain
IEDFAACK_03655 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
IEDFAACK_03656 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IEDFAACK_03657 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IEDFAACK_03658 2e-94 ywhD S YwhD family
IEDFAACK_03659 5.1e-119 ywhC S Peptidase family M50
IEDFAACK_03660 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
IEDFAACK_03661 3.3e-71 ywhA K Transcriptional regulator
IEDFAACK_03662 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IEDFAACK_03664 2.6e-237 mmr U Major Facilitator Superfamily
IEDFAACK_03665 6.2e-79 yffB K Transcriptional regulator
IEDFAACK_03666 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
IEDFAACK_03667 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
IEDFAACK_03668 3.1e-36 ywzC S Belongs to the UPF0741 family
IEDFAACK_03669 5.1e-110 rsfA_1
IEDFAACK_03670 2.2e-157 ywfM EG EamA-like transporter family
IEDFAACK_03671 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IEDFAACK_03672 1.1e-156 cysL K Transcriptional regulator
IEDFAACK_03673 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
IEDFAACK_03674 3.3e-146 ywfI C May function as heme-dependent peroxidase
IEDFAACK_03675 7.5e-138 IQ Enoyl-(Acyl carrier protein) reductase
IEDFAACK_03676 6e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
IEDFAACK_03677 1.9e-209 bacE EGP Major facilitator Superfamily
IEDFAACK_03678 3e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IEDFAACK_03679 5.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEDFAACK_03680 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IEDFAACK_03681 7.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IEDFAACK_03682 1.3e-205 ywfA EGP Major facilitator Superfamily
IEDFAACK_03683 2.8e-249 lysP E amino acid
IEDFAACK_03684 0.0 rocB E arginine degradation protein
IEDFAACK_03685 4.1e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IEDFAACK_03686 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IEDFAACK_03687 1.2e-77
IEDFAACK_03688 1.3e-86 spsL 5.1.3.13 M Spore Coat
IEDFAACK_03689 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IEDFAACK_03690 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IEDFAACK_03691 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IEDFAACK_03692 7.9e-188 spsG M Spore Coat
IEDFAACK_03693 9.7e-132 spsF M Spore Coat
IEDFAACK_03694 7.1e-214 spsE 2.5.1.56 M acid synthase
IEDFAACK_03695 2.2e-162 spsD 2.3.1.210 K Spore Coat
IEDFAACK_03696 2.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
IEDFAACK_03697 5.6e-269 spsB M Capsule polysaccharide biosynthesis protein
IEDFAACK_03698 1e-142 spsA M Spore Coat
IEDFAACK_03699 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IEDFAACK_03700 4.3e-59 ywdK S small membrane protein
IEDFAACK_03701 3.7e-238 ywdJ F Xanthine uracil
IEDFAACK_03702 1.3e-48 ywdI S Family of unknown function (DUF5327)
IEDFAACK_03703 6.1e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IEDFAACK_03704 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IEDFAACK_03705 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
IEDFAACK_03706 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IEDFAACK_03707 2e-28 ywdA
IEDFAACK_03708 5.4e-291 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
IEDFAACK_03709 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEDFAACK_03710 5.7e-138 focA P Formate/nitrite transporter
IEDFAACK_03711 7e-150 sacT K transcriptional antiterminator
IEDFAACK_03713 0.0 vpr O Belongs to the peptidase S8 family
IEDFAACK_03714 8.1e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEDFAACK_03715 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
IEDFAACK_03716 8.6e-202 rodA D Belongs to the SEDS family
IEDFAACK_03717 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
IEDFAACK_03718 1e-63 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IEDFAACK_03719 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IEDFAACK_03720 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IEDFAACK_03721 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IEDFAACK_03722 1e-35 ywzA S membrane
IEDFAACK_03723 1.9e-297 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IEDFAACK_03724 1.2e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IEDFAACK_03725 9.5e-60 gtcA S GtrA-like protein
IEDFAACK_03726 1.1e-121 ywcC K transcriptional regulator
IEDFAACK_03728 2.9e-48 ywcB S Protein of unknown function, DUF485
IEDFAACK_03729 5.3e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEDFAACK_03730 8.1e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IEDFAACK_03731 4.9e-224 ywbN P Dyp-type peroxidase family protein
IEDFAACK_03732 9.3e-185 ycdO P periplasmic lipoprotein involved in iron transport
IEDFAACK_03733 3e-249 P COG0672 High-affinity Fe2 Pb2 permease
IEDFAACK_03734 1.2e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IEDFAACK_03735 4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IEDFAACK_03736 1.6e-152 ywbI K Transcriptional regulator
IEDFAACK_03737 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IEDFAACK_03738 2.3e-111 ywbG M effector of murein hydrolase
IEDFAACK_03739 1.3e-208 ywbF EGP Major facilitator Superfamily
IEDFAACK_03740 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
IEDFAACK_03741 2.4e-220 ywbD 2.1.1.191 J Methyltransferase
IEDFAACK_03742 9.9e-67 ywbC 4.4.1.5 E glyoxalase
IEDFAACK_03743 6.1e-120 ywbB S Protein of unknown function (DUF2711)
IEDFAACK_03744 2.1e-48 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFAACK_03745 5.6e-173 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFAACK_03746 9.2e-270 epr 3.4.21.62 O Belongs to the peptidase S8 family
IEDFAACK_03747 2e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEDFAACK_03748 9.9e-152 sacY K transcriptional antiterminator
IEDFAACK_03749 4.5e-168 gspA M General stress
IEDFAACK_03750 1.3e-123 ywaF S Integral membrane protein
IEDFAACK_03751 4e-87 ywaE K Transcriptional regulator
IEDFAACK_03752 6.6e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IEDFAACK_03753 8.8e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
IEDFAACK_03754 5.1e-115 ywaC 2.7.6.5 S protein conserved in bacteria
IEDFAACK_03755 5.1e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
IEDFAACK_03756 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
IEDFAACK_03757 1.1e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_03758 1.2e-232 dltB M membrane protein involved in D-alanine export
IEDFAACK_03759 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEDFAACK_03760 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IEDFAACK_03761 2.5e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFAACK_03762 1.2e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IEDFAACK_03763 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IEDFAACK_03764 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
IEDFAACK_03765 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEDFAACK_03766 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
IEDFAACK_03767 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
IEDFAACK_03768 1.1e-19 yxzF
IEDFAACK_03769 1.1e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IEDFAACK_03770 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IEDFAACK_03771 8.7e-210 yxlH EGP Major facilitator Superfamily
IEDFAACK_03772 3.4e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IEDFAACK_03773 1.1e-164 yxlF V ABC transporter, ATP-binding protein
IEDFAACK_03774 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
IEDFAACK_03775 1.4e-30
IEDFAACK_03776 3.9e-48 yxlC S Family of unknown function (DUF5345)
IEDFAACK_03777 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
IEDFAACK_03778 1.1e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
IEDFAACK_03779 7.7e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IEDFAACK_03780 0.0 cydD V ATP-binding protein
IEDFAACK_03781 1.7e-310 cydD V ATP-binding
IEDFAACK_03782 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
IEDFAACK_03783 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
IEDFAACK_03784 1.5e-229 cimH C COG3493 Na citrate symporter
IEDFAACK_03785 9.4e-311 3.4.24.84 O Peptidase family M48
IEDFAACK_03787 2.1e-154 yxkH G Polysaccharide deacetylase
IEDFAACK_03788 5.9e-205 msmK P Belongs to the ABC transporter superfamily
IEDFAACK_03789 3.5e-163 lrp QT PucR C-terminal helix-turn-helix domain
IEDFAACK_03790 2.2e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IEDFAACK_03791 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEDFAACK_03792 1.4e-73 yxkC S Domain of unknown function (DUF4352)
IEDFAACK_03793 3.9e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IEDFAACK_03794 2e-77 S Protein of unknown function (DUF1453)
IEDFAACK_03795 2.4e-191 yxjM T Signal transduction histidine kinase
IEDFAACK_03796 2.9e-114 K helix_turn_helix, Lux Regulon
IEDFAACK_03797 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IEDFAACK_03800 1.3e-84 yxjI S LURP-one-related
IEDFAACK_03801 1.4e-217 yxjG 2.1.1.14 E Methionine synthase
IEDFAACK_03802 1.7e-218 yxjG 2.1.1.14 E Methionine synthase
IEDFAACK_03803 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IEDFAACK_03804 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IEDFAACK_03805 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEDFAACK_03806 4.9e-252 yxjC EG COG2610 H gluconate symporter and related permeases
IEDFAACK_03807 2.7e-157 rlmA 2.1.1.187 Q Methyltransferase domain
IEDFAACK_03808 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IEDFAACK_03809 1.2e-104 T Domain of unknown function (DUF4163)
IEDFAACK_03810 3e-47 yxiS
IEDFAACK_03811 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
IEDFAACK_03812 6.6e-224 citH C Citrate transporter
IEDFAACK_03813 1.1e-143 exoK GH16 M licheninase activity
IEDFAACK_03814 8.3e-151 licT K transcriptional antiterminator
IEDFAACK_03815 7.6e-110
IEDFAACK_03816 1.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
IEDFAACK_03817 1.3e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IEDFAACK_03818 1e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
IEDFAACK_03821 7.3e-41 yxiJ S YxiJ-like protein
IEDFAACK_03822 8.7e-84 yxiI S Protein of unknown function (DUF2716)
IEDFAACK_03823 4.4e-139
IEDFAACK_03824 5.1e-69 yxiG
IEDFAACK_03825 7.3e-59
IEDFAACK_03826 1.1e-83
IEDFAACK_03827 1.5e-71 yxxG
IEDFAACK_03828 0.0 wapA M COG3209 Rhs family protein
IEDFAACK_03829 1.9e-164 yxxF EG EamA-like transporter family
IEDFAACK_03830 5.4e-72 yxiE T Belongs to the universal stress protein A family
IEDFAACK_03831 2e-277 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFAACK_03832 8e-70 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEDFAACK_03833 5.4e-219 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEDFAACK_03834 2.9e-216 S nuclease activity
IEDFAACK_03835 1.4e-38 yxiC S Family of unknown function (DUF5344)
IEDFAACK_03836 2.3e-20 S Domain of unknown function (DUF5082)
IEDFAACK_03837 2.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IEDFAACK_03838 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IEDFAACK_03839 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
IEDFAACK_03840 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IEDFAACK_03841 4.4e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
IEDFAACK_03842 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IEDFAACK_03843 3.4e-250 lysP E amino acid
IEDFAACK_03844 8.7e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
IEDFAACK_03845 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IEDFAACK_03846 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IEDFAACK_03847 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IEDFAACK_03848 2e-152 yxxB S Domain of Unknown Function (DUF1206)
IEDFAACK_03849 5.1e-196 eutH E Ethanolamine utilisation protein, EutH
IEDFAACK_03850 8.6e-251 yxeQ S MmgE/PrpD family
IEDFAACK_03851 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
IEDFAACK_03852 1.7e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
IEDFAACK_03853 1.2e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
IEDFAACK_03854 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
IEDFAACK_03855 1.6e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEDFAACK_03856 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEDFAACK_03857 1.4e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IEDFAACK_03858 1.5e-149 yidA S hydrolases of the HAD superfamily
IEDFAACK_03861 2.5e-14 yxeE
IEDFAACK_03862 5.6e-16 yxeD
IEDFAACK_03863 8.5e-69
IEDFAACK_03864 1.1e-175 fhuD P ABC transporter
IEDFAACK_03865 1.3e-57 yxeA S Protein of unknown function (DUF1093)
IEDFAACK_03866 0.0 yxdM V ABC transporter (permease)
IEDFAACK_03867 3.7e-137 yxdL V ABC transporter, ATP-binding protein
IEDFAACK_03868 1.1e-178 T PhoQ Sensor
IEDFAACK_03869 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_03870 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IEDFAACK_03871 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IEDFAACK_03872 3e-167 iolH G Xylose isomerase-like TIM barrel
IEDFAACK_03873 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IEDFAACK_03874 5.1e-235 iolF EGP Major facilitator Superfamily
IEDFAACK_03875 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IEDFAACK_03876 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IEDFAACK_03877 7.9e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IEDFAACK_03878 1.6e-151 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IEDFAACK_03879 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IEDFAACK_03880 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
IEDFAACK_03881 4.1e-175 iolS C Aldo keto reductase
IEDFAACK_03883 8.3e-48 yxcD S Protein of unknown function (DUF2653)
IEDFAACK_03884 1.5e-245 csbC EGP Major facilitator Superfamily
IEDFAACK_03885 0.0 htpG O Molecular chaperone. Has ATPase activity
IEDFAACK_03887 3.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
IEDFAACK_03888 4.5e-208 yxbF K Bacterial regulatory proteins, tetR family
IEDFAACK_03889 1.2e-244 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IEDFAACK_03890 3.2e-48 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
IEDFAACK_03891 8.3e-91 S PQQ-like domain
IEDFAACK_03892 1.1e-63 S Family of unknown function (DUF5391)
IEDFAACK_03893 1.4e-75 yxaI S membrane protein domain
IEDFAACK_03894 4.6e-227 P Protein of unknown function (DUF418)
IEDFAACK_03895 6.4e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
IEDFAACK_03896 2.7e-100 yxaF K Transcriptional regulator
IEDFAACK_03897 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IEDFAACK_03898 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
IEDFAACK_03899 5.2e-50 S LrgA family
IEDFAACK_03900 2.6e-118 yxaC M effector of murein hydrolase
IEDFAACK_03901 5.9e-191 yxaB GM Polysaccharide pyruvyl transferase
IEDFAACK_03902 4.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IEDFAACK_03903 7.3e-127 gntR K transcriptional
IEDFAACK_03904 1.7e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
IEDFAACK_03905 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
IEDFAACK_03906 4.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IEDFAACK_03907 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
IEDFAACK_03908 2.5e-286 ahpF O Alkyl hydroperoxide reductase
IEDFAACK_03909 1.3e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEDFAACK_03910 1.6e-123 yydK K Transcriptional regulator
IEDFAACK_03911 8.4e-12
IEDFAACK_03912 9.5e-119 S ABC-2 family transporter protein
IEDFAACK_03913 5.9e-109 prrC P ABC transporter
IEDFAACK_03914 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
IEDFAACK_03915 4.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IEDFAACK_03916 1.1e-09 S YyzF-like protein
IEDFAACK_03917 8.2e-59
IEDFAACK_03918 6.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IEDFAACK_03920 8.2e-30 yycQ S Protein of unknown function (DUF2651)
IEDFAACK_03921 3.9e-207 yycP
IEDFAACK_03922 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IEDFAACK_03923 8.4e-84 yycN 2.3.1.128 K Acetyltransferase
IEDFAACK_03924 1.1e-187 S aspartate phosphatase
IEDFAACK_03926 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
IEDFAACK_03927 1.4e-254 rocE E amino acid
IEDFAACK_03928 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
IEDFAACK_03929 4.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IEDFAACK_03930 1.9e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEDFAACK_03931 4.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IEDFAACK_03932 7.3e-155 yycI S protein conserved in bacteria
IEDFAACK_03933 4.9e-257 yycH S protein conserved in bacteria
IEDFAACK_03934 0.0 vicK 2.7.13.3 T Histidine kinase
IEDFAACK_03935 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEDFAACK_03940 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IEDFAACK_03941 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEDFAACK_03942 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IEDFAACK_03943 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
IEDFAACK_03945 1.9e-15 yycC K YycC-like protein
IEDFAACK_03946 8.4e-221 yeaN P COG2807 Cyanate permease
IEDFAACK_03947 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IEDFAACK_03948 4.9e-73 rplI J binds to the 23S rRNA
IEDFAACK_03949 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IEDFAACK_03950 1.1e-159 yybS S membrane
IEDFAACK_03952 3.9e-84 cotF M Spore coat protein
IEDFAACK_03953 1.7e-66 ydeP3 K Transcriptional regulator
IEDFAACK_03954 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
IEDFAACK_03955 5.6e-61
IEDFAACK_03957 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
IEDFAACK_03958 1.4e-120
IEDFAACK_03959 1.9e-65 yybH S SnoaL-like domain
IEDFAACK_03960 6.2e-122 yybG S Pentapeptide repeat-containing protein
IEDFAACK_03961 8.8e-218 ynfM EGP Major facilitator Superfamily
IEDFAACK_03962 4.5e-163 yybE K Transcriptional regulator
IEDFAACK_03963 2e-79 yjcF S Acetyltransferase (GNAT) domain
IEDFAACK_03964 1.5e-75 yybC
IEDFAACK_03965 3e-127 S Metallo-beta-lactamase superfamily
IEDFAACK_03966 5.6e-77 yybA 2.3.1.57 K transcriptional
IEDFAACK_03967 1.3e-70 yjcF S Acetyltransferase (GNAT) domain
IEDFAACK_03968 5.5e-96 yyaS S Membrane
IEDFAACK_03969 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
IEDFAACK_03970 7.8e-66 yyaQ S YjbR
IEDFAACK_03971 3.6e-105 yyaP 1.5.1.3 H RibD C-terminal domain
IEDFAACK_03972 6.6e-246 tetL EGP Major facilitator Superfamily
IEDFAACK_03973 1.2e-41 yyaL O Highly conserved protein containing a thioredoxin domain
IEDFAACK_03974 2.5e-60 yyaN K MerR HTH family regulatory protein
IEDFAACK_03975 6.3e-160 yyaM EG EamA-like transporter family
IEDFAACK_03976 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
IEDFAACK_03977 3.4e-166 yyaK S CAAX protease self-immunity
IEDFAACK_03978 1.8e-243 EGP Major facilitator superfamily
IEDFAACK_03979 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
IEDFAACK_03980 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEDFAACK_03981 1.7e-176 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
IEDFAACK_03982 2.2e-142 xth 3.1.11.2 L exodeoxyribonuclease III
IEDFAACK_03983 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IEDFAACK_03984 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IEDFAACK_03985 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
IEDFAACK_03986 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IEDFAACK_03987 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IEDFAACK_03988 2.3e-33 yyzM S protein conserved in bacteria
IEDFAACK_03989 4e-176 yyaD S Membrane
IEDFAACK_03990 1.6e-111 yyaC S Sporulation protein YyaC
IEDFAACK_03991 2.1e-149 spo0J K Belongs to the ParB family
IEDFAACK_03992 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
IEDFAACK_03993 3.7e-73 S Bacterial PH domain
IEDFAACK_03994 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IEDFAACK_03995 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IEDFAACK_03996 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IEDFAACK_03997 5.4e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IEDFAACK_03998 6.5e-108 jag S single-stranded nucleic acid binding R3H
IEDFAACK_03999 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IEDFAACK_04000 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)