ORF_ID e_value Gene_name EC_number CAZy COGs Description
MNHILNHP_00004 5.1e-13 ard S Antirestriction protein (ArdA)
MNHILNHP_00011 7.8e-26
MNHILNHP_00012 3.9e-15 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MNHILNHP_00021 8.5e-11
MNHILNHP_00022 2.2e-40 doc S Fic/DOC family
MNHILNHP_00023 3.3e-21 relB L Addiction module antitoxin, RelB DinJ family
MNHILNHP_00024 4.9e-22
MNHILNHP_00029 4e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MNHILNHP_00030 2.7e-35
MNHILNHP_00032 2.5e-88 L Belongs to the 'phage' integrase family
MNHILNHP_00034 1.2e-10 2.7.1.24 H dephospho-CoA kinase activity
MNHILNHP_00036 1.8e-18
MNHILNHP_00037 3.3e-18 L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MNHILNHP_00038 9.4e-69 S hydrolase activity
MNHILNHP_00039 1.8e-30
MNHILNHP_00041 2.5e-97 3.6.4.12 L DnaB-like helicase C terminal domain
MNHILNHP_00044 8.2e-173 tnpB L Putative transposase DNA-binding domain
MNHILNHP_00045 7.2e-112 recD 3.1.11.5 L Helix-hairpin-helix containing domain
MNHILNHP_00048 1.2e-42
MNHILNHP_00049 1.2e-114 pnuC H nicotinamide mononucleotide transporter
MNHILNHP_00051 6.9e-11 nrdH O Glutaredoxin
MNHILNHP_00058 6.6e-75 dck 2.7.1.74 F deoxynucleoside kinase
MNHILNHP_00076 5.1e-180 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
MNHILNHP_00077 2.5e-09 L helicase
MNHILNHP_00079 2e-82 L Integrase
MNHILNHP_00080 2.1e-28 lytE M Lysin motif
MNHILNHP_00081 1.4e-48 tdk 2.7.1.21 F Thymidine kinase
MNHILNHP_00083 6.8e-36 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MNHILNHP_00086 1.1e-11
MNHILNHP_00090 3.9e-58 S helicase activity
MNHILNHP_00094 1e-31 S Protein of unknown function (DUF1064)
MNHILNHP_00095 3.7e-63 S DNA ligase (ATP) activity
MNHILNHP_00097 3.8e-61 dnaE_2 2.7.7.7 L DNA polymerase
MNHILNHP_00098 2.2e-18 1.1.98.6, 3.6.3.14, 3.6.3.15, 4.1.1.35 L LAGLIDADG-like domain
MNHILNHP_00099 3.1e-162 dnaE_2 2.7.7.7 L DNA polymerase
MNHILNHP_00100 4.2e-39 S PD-(D/E)XK nuclease superfamily
MNHILNHP_00101 1.1e-38 S DNA primase activity
MNHILNHP_00103 1.9e-65 3.2.1.26, 3.2.1.65 GH32 M Glycosyl hydrolases family 32
MNHILNHP_00104 8.4e-118 S Glycosyl hydrolases family 25
MNHILNHP_00105 1.7e-60 S regulation of transcription, DNA-dependent
MNHILNHP_00106 3.2e-07
MNHILNHP_00109 3.1e-08
MNHILNHP_00110 2e-105 fliC N bacterial-type flagellum-dependent cell motility
MNHILNHP_00111 1.1e-67
MNHILNHP_00112 2.7e-52
MNHILNHP_00114 2.5e-51 D Phage-related minor tail protein
MNHILNHP_00115 4.7e-79 xerH L Belongs to the 'phage' integrase family
MNHILNHP_00118 2.7e-10 hol S COG5546 Small integral membrane protein
MNHILNHP_00120 2.9e-07
MNHILNHP_00122 1e-16
MNHILNHP_00123 5.8e-35 GT2,GT4 O gp58-like protein
MNHILNHP_00124 9e-28
MNHILNHP_00130 4.2e-61
MNHILNHP_00132 3.7e-52
MNHILNHP_00133 2.9e-35
MNHILNHP_00134 1.8e-143 gp17a S Terminase-like family
MNHILNHP_00135 1.6e-09
MNHILNHP_00141 4.9e-13 S Replication initiator protein A (RepA) N-terminus
MNHILNHP_00142 1e-49 soj D AAA domain
MNHILNHP_00144 3e-37
MNHILNHP_00146 9.3e-80 tlpA2 L Transposase IS200 like
MNHILNHP_00147 6.2e-227 L transposase, IS605 OrfB family
MNHILNHP_00149 8.4e-52
MNHILNHP_00150 0.0 M Phage tail tape measure protein TP901
MNHILNHP_00151 5.7e-32
MNHILNHP_00152 6.9e-58
MNHILNHP_00153 1.7e-71 S Phage tail tube protein, TTP
MNHILNHP_00154 2.1e-50
MNHILNHP_00155 9.5e-79
MNHILNHP_00156 4.6e-58
MNHILNHP_00157 6.2e-35
MNHILNHP_00158 1.2e-167 S Phage major capsid protein E
MNHILNHP_00159 9.3e-54
MNHILNHP_00160 5.3e-52 S Domain of unknown function (DUF4355)
MNHILNHP_00161 5.2e-150 S Phage Mu protein F like protein
MNHILNHP_00162 1.3e-218 S Phage portal protein, SPP1 Gp6-like
MNHILNHP_00163 6.4e-219 S Terminase-like family
MNHILNHP_00164 7.8e-112 xtmA L Terminase small subunit
MNHILNHP_00166 5.6e-67 S Domain of unknown function (DUF4417)
MNHILNHP_00171 1.9e-36
MNHILNHP_00174 1.2e-60 rusA L Endodeoxyribonuclease RusA
MNHILNHP_00175 2e-16
MNHILNHP_00182 1.7e-56 S ORF6C domain
MNHILNHP_00185 2e-56 dnaC 3.4.21.53 L IstB-like ATP binding protein
MNHILNHP_00186 6.3e-73 ybl78 L DnaD domain protein
MNHILNHP_00187 1.1e-14 L Single-strand binding protein family
MNHILNHP_00188 1e-50 S ERF superfamily
MNHILNHP_00197 6.2e-65 S DNA binding
MNHILNHP_00198 5.9e-26 K Helix-turn-helix XRE-family like proteins
MNHILNHP_00199 1.3e-51 K Cro/C1-type HTH DNA-binding domain
MNHILNHP_00200 5.9e-42 E Zn peptidase
MNHILNHP_00201 2.9e-10
MNHILNHP_00202 1.5e-42
MNHILNHP_00203 1.2e-07
MNHILNHP_00204 1.2e-49
MNHILNHP_00205 3.4e-99 L Belongs to the 'phage' integrase family
MNHILNHP_00206 1.1e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MNHILNHP_00207 8e-82 F Belongs to the NrdI family
MNHILNHP_00208 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MNHILNHP_00209 3.2e-101 ypsA S Belongs to the UPF0398 family
MNHILNHP_00210 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MNHILNHP_00211 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MNHILNHP_00212 1.3e-160 EG EamA-like transporter family
MNHILNHP_00213 8.1e-123 dnaD L DnaD domain protein
MNHILNHP_00214 6.9e-87 ypmB S Protein conserved in bacteria
MNHILNHP_00215 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MNHILNHP_00216 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MNHILNHP_00217 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MNHILNHP_00218 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MNHILNHP_00219 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MNHILNHP_00220 2.5e-86 S Protein of unknown function (DUF1440)
MNHILNHP_00221 2.3e-133 L Transposase
MNHILNHP_00222 4.4e-126 tnp L DDE domain
MNHILNHP_00223 9.3e-51 L Transposase
MNHILNHP_00224 1.3e-116 L transposase IS116 IS110 IS902 family protein
MNHILNHP_00225 2.4e-77 L Bacterial dnaA protein
MNHILNHP_00226 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MNHILNHP_00227 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MNHILNHP_00228 7.8e-263 argH 4.3.2.1 E argininosuccinate lyase
MNHILNHP_00229 3.8e-83 bioY S BioY family
MNHILNHP_00230 5.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MNHILNHP_00231 1.1e-181 phoH T phosphate starvation-inducible protein PhoH
MNHILNHP_00232 3.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MNHILNHP_00233 3.8e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MNHILNHP_00234 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MNHILNHP_00235 3.8e-145 recO L Involved in DNA repair and RecF pathway recombination
MNHILNHP_00236 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MNHILNHP_00237 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MNHILNHP_00238 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MNHILNHP_00239 7.7e-208 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MNHILNHP_00240 2.4e-220 patA 2.6.1.1 E Aminotransferase
MNHILNHP_00241 6.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
MNHILNHP_00242 6.5e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MNHILNHP_00243 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MNHILNHP_00244 2e-29 S Protein of unknown function (DUF2929)
MNHILNHP_00245 0.0 dnaE 2.7.7.7 L DNA polymerase
MNHILNHP_00246 3.6e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MNHILNHP_00247 9.3e-169 cvfB S S1 domain
MNHILNHP_00248 1e-162 xerD D recombinase XerD
MNHILNHP_00249 2.8e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MNHILNHP_00250 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MNHILNHP_00251 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MNHILNHP_00252 5.9e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MNHILNHP_00253 2.1e-100 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MNHILNHP_00254 2.6e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
MNHILNHP_00255 2.4e-267 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
MNHILNHP_00256 2.5e-13 M Lysin motif
MNHILNHP_00257 1.3e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MNHILNHP_00258 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MNHILNHP_00259 4.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MNHILNHP_00260 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MNHILNHP_00261 1.7e-232 S Tetratricopeptide repeat protein
MNHILNHP_00262 4.5e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MNHILNHP_00263 0.0 yfmR S ABC transporter, ATP-binding protein
MNHILNHP_00264 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MNHILNHP_00265 9.6e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MNHILNHP_00266 1.9e-110 hlyIII S protein, hemolysin III
MNHILNHP_00267 4.9e-151 DegV S EDD domain protein, DegV family
MNHILNHP_00268 5.4e-167 ypmR E lipolytic protein G-D-S-L family
MNHILNHP_00269 8.2e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MNHILNHP_00270 4.4e-35 yozE S Belongs to the UPF0346 family
MNHILNHP_00271 2.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MNHILNHP_00272 4.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MNHILNHP_00277 1.3e-129 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MNHILNHP_00278 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MNHILNHP_00279 8.4e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MNHILNHP_00280 3.8e-254 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MNHILNHP_00281 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MNHILNHP_00282 2e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MNHILNHP_00283 7.8e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MNHILNHP_00284 1.3e-123 IQ reductase
MNHILNHP_00285 1.2e-153 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MNHILNHP_00286 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MNHILNHP_00287 1.8e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MNHILNHP_00288 1.2e-76 marR K Transcriptional regulator, MarR family
MNHILNHP_00289 8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MNHILNHP_00291 5.6e-200 xerS L Belongs to the 'phage' integrase family
MNHILNHP_00292 6.9e-132 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
MNHILNHP_00293 3.6e-99 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
MNHILNHP_00294 3e-156 rssA S Phospholipase, patatin family
MNHILNHP_00295 9.4e-118 L Integrase
MNHILNHP_00296 4.2e-153 EG EamA-like transporter family
MNHILNHP_00297 7.4e-129 narI 1.7.5.1 C Nitrate reductase
MNHILNHP_00298 2.7e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
MNHILNHP_00299 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
MNHILNHP_00300 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MNHILNHP_00301 1.4e-184 moeB 2.7.7.73, 2.7.7.80 H ThiF family
MNHILNHP_00302 2.6e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MNHILNHP_00303 5.3e-223 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
MNHILNHP_00304 2e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MNHILNHP_00305 7.1e-101 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MNHILNHP_00306 2.6e-43
MNHILNHP_00307 2.1e-183 comP 2.7.13.3 F Sensor histidine kinase
MNHILNHP_00308 9.8e-115 nreC K PFAM regulatory protein LuxR
MNHILNHP_00309 1.2e-18
MNHILNHP_00310 4.4e-172
MNHILNHP_00311 5.7e-145 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
MNHILNHP_00312 2.5e-217 narK P Transporter, major facilitator family protein
MNHILNHP_00313 3.9e-32 moaD 2.8.1.12 H ThiS family
MNHILNHP_00314 3.5e-62 moaE 2.8.1.12 H MoaE protein
MNHILNHP_00315 2.5e-77 S Flavodoxin
MNHILNHP_00316 1e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MNHILNHP_00317 2.9e-134 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
MNHILNHP_00318 2e-175 fecB P Periplasmic binding protein
MNHILNHP_00319 2e-172
MNHILNHP_00320 4e-72
MNHILNHP_00321 6e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MNHILNHP_00322 4.9e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MNHILNHP_00323 6.1e-117 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MNHILNHP_00324 1.3e-227 clcA_2 P Chloride transporter, ClC family
MNHILNHP_00325 6.5e-136 L PFAM transposase IS116 IS110 IS902
MNHILNHP_00326 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MNHILNHP_00327 1.9e-110 lssY 3.6.1.27 I Acid phosphatase homologues
MNHILNHP_00328 1.3e-76 lytE M Lysin motif
MNHILNHP_00329 1.1e-147 XK27_02985 S Cof-like hydrolase
MNHILNHP_00330 1.8e-78 K Transcriptional regulator
MNHILNHP_00331 0.0 oatA I Acyltransferase
MNHILNHP_00332 5.6e-52
MNHILNHP_00333 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MNHILNHP_00334 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MNHILNHP_00335 5.8e-126 ybbR S YbbR-like protein
MNHILNHP_00336 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MNHILNHP_00337 3.7e-249 fucP G Major Facilitator Superfamily
MNHILNHP_00338 1.1e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MNHILNHP_00339 6.1e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MNHILNHP_00340 3e-167 murB 1.3.1.98 M Cell wall formation
MNHILNHP_00341 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
MNHILNHP_00342 4.4e-76 S PAS domain
MNHILNHP_00343 2.3e-87 K Acetyltransferase (GNAT) domain
MNHILNHP_00344 2e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MNHILNHP_00345 3.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MNHILNHP_00346 9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MNHILNHP_00347 6.3e-105 yxjI
MNHILNHP_00348 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MNHILNHP_00349 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MNHILNHP_00350 2.2e-131 est 3.1.1.1 S Serine aminopeptidase, S33
MNHILNHP_00351 1.8e-34 secG U Preprotein translocase
MNHILNHP_00352 2.4e-292 clcA P chloride
MNHILNHP_00353 3.6e-244 yifK E Amino acid permease
MNHILNHP_00354 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MNHILNHP_00355 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MNHILNHP_00356 1.2e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MNHILNHP_00357 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MNHILNHP_00359 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MNHILNHP_00360 2.4e-131 glpT G Major Facilitator Superfamily
MNHILNHP_00361 1.5e-71 glpT G Major Facilitator Superfamily
MNHILNHP_00362 8.8e-15
MNHILNHP_00364 1.5e-169 whiA K May be required for sporulation
MNHILNHP_00365 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MNHILNHP_00366 4.9e-162 rapZ S Displays ATPase and GTPase activities
MNHILNHP_00367 1.6e-244 steT E amino acid
MNHILNHP_00368 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MNHILNHP_00369 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MNHILNHP_00370 9.1e-14
MNHILNHP_00371 5.1e-116 yfbR S HD containing hydrolase-like enzyme
MNHILNHP_00372 8.3e-238 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
MNHILNHP_00373 1.1e-127 IQ Dehydrogenase reductase
MNHILNHP_00374 3.2e-36
MNHILNHP_00375 7.7e-112 ywnB S NAD(P)H-binding
MNHILNHP_00376 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
MNHILNHP_00377 1.2e-253 nhaC C Na H antiporter NhaC
MNHILNHP_00378 1.1e-181 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MNHILNHP_00380 4.1e-98 ydeN S Serine hydrolase
MNHILNHP_00381 2.9e-27 psiE S Phosphate-starvation-inducible E
MNHILNHP_00382 8.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MNHILNHP_00384 1.2e-177 S Aldo keto reductase
MNHILNHP_00385 3.7e-61 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
MNHILNHP_00386 0.0 L Helicase C-terminal domain protein
MNHILNHP_00388 3.2e-245 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MNHILNHP_00389 2.6e-52 S Sugar efflux transporter for intercellular exchange
MNHILNHP_00390 2.3e-125
MNHILNHP_00391 1.3e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MNHILNHP_00392 2.5e-311 cadA P P-type ATPase
MNHILNHP_00393 1.2e-219 5.4.2.7 G Metalloenzyme superfamily
MNHILNHP_00395 1.2e-35 1.6.5.2 GM NAD(P)H-binding
MNHILNHP_00396 1.6e-50 1.6.5.2 GM NAD(P)H-binding
MNHILNHP_00397 7.6e-74 K Transcriptional regulator
MNHILNHP_00398 6e-163 proX M ABC transporter, substrate-binding protein, QAT family
MNHILNHP_00399 2.4e-108 proWZ P ABC transporter permease
MNHILNHP_00400 6.5e-142 proV E ABC transporter, ATP-binding protein
MNHILNHP_00401 1.9e-102 proW P ABC transporter, permease protein
MNHILNHP_00402 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MNHILNHP_00403 2.3e-60 clcA P chloride
MNHILNHP_00404 1.5e-56 clcA P chloride
MNHILNHP_00405 1.4e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MNHILNHP_00406 3.1e-103 metI P ABC transporter permease
MNHILNHP_00407 4e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MNHILNHP_00408 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
MNHILNHP_00409 5.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MNHILNHP_00410 2.9e-221 norA EGP Major facilitator Superfamily
MNHILNHP_00411 2e-40 1.3.5.4 S FMN binding
MNHILNHP_00412 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MNHILNHP_00413 1.4e-262 yfnA E amino acid
MNHILNHP_00414 4.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MNHILNHP_00416 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MNHILNHP_00417 0.0 helD 3.6.4.12 L DNA helicase
MNHILNHP_00418 1.1e-80 ndk 2.7.4.6 F Belongs to the NDK family
MNHILNHP_00419 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MNHILNHP_00420 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MNHILNHP_00421 0.0 dnaK O Heat shock 70 kDa protein
MNHILNHP_00422 3.9e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MNHILNHP_00423 5.9e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MNHILNHP_00424 7.6e-64
MNHILNHP_00425 1.9e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MNHILNHP_00426 4.2e-164 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MNHILNHP_00427 6.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MNHILNHP_00428 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MNHILNHP_00429 1.3e-48 ylxQ J ribosomal protein
MNHILNHP_00430 1e-44 ylxR K Protein of unknown function (DUF448)
MNHILNHP_00431 1.4e-215 nusA K Participates in both transcription termination and antitermination
MNHILNHP_00432 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
MNHILNHP_00433 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MNHILNHP_00434 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MNHILNHP_00435 1.1e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MNHILNHP_00436 7.6e-138 cdsA 2.7.7.41 I Belongs to the CDS family
MNHILNHP_00437 1e-139 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MNHILNHP_00438 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MNHILNHP_00439 4.1e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MNHILNHP_00440 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MNHILNHP_00441 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
MNHILNHP_00442 5.9e-180 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNHILNHP_00443 5.4e-49 yazA L GIY-YIG catalytic domain protein
MNHILNHP_00444 5.4e-141 yabB 2.1.1.223 L Methyltransferase small domain
MNHILNHP_00445 1.6e-117 plsC 2.3.1.51 I Acyltransferase
MNHILNHP_00446 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
MNHILNHP_00447 1.3e-35 ynzC S UPF0291 protein
MNHILNHP_00448 2.1e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MNHILNHP_00449 4.6e-208 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MNHILNHP_00450 1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MNHILNHP_00452 7.3e-88
MNHILNHP_00453 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MNHILNHP_00454 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MNHILNHP_00455 2.1e-154 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MNHILNHP_00456 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MNHILNHP_00457 5.2e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MNHILNHP_00458 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MNHILNHP_00459 1.1e-07
MNHILNHP_00460 1.4e-265 yjeM E Amino Acid
MNHILNHP_00461 1.8e-232 V MatE
MNHILNHP_00462 7.4e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MNHILNHP_00463 1.3e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MNHILNHP_00464 1.6e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MNHILNHP_00465 4.8e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNHILNHP_00466 5.3e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MNHILNHP_00467 6.7e-59 yodB K Transcriptional regulator, HxlR family
MNHILNHP_00468 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MNHILNHP_00469 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MNHILNHP_00470 3.6e-114 rlpA M PFAM NLP P60 protein
MNHILNHP_00471 8e-117 udk 2.7.1.48 F Cytidine monophosphokinase
MNHILNHP_00472 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MNHILNHP_00473 3.1e-68 yneR S Belongs to the HesB IscA family
MNHILNHP_00474 0.0 S membrane
MNHILNHP_00475 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MNHILNHP_00476 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MNHILNHP_00477 5.2e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MNHILNHP_00478 1.4e-108 gluP 3.4.21.105 S Peptidase, S54 family
MNHILNHP_00479 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
MNHILNHP_00480 1.4e-181 glk 2.7.1.2 G Glucokinase
MNHILNHP_00481 3.4e-67 yqhL P Rhodanese-like protein
MNHILNHP_00482 5.9e-22 S Protein of unknown function (DUF3042)
MNHILNHP_00483 2.9e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MNHILNHP_00484 4e-264 glnA 6.3.1.2 E glutamine synthetase
MNHILNHP_00485 6.4e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MNHILNHP_00486 1.8e-212 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MNHILNHP_00487 3.9e-12
MNHILNHP_00489 6e-78 L Belongs to the 'phage' integrase family
MNHILNHP_00490 2.1e-10 E Zn peptidase
MNHILNHP_00491 1.9e-18 S protein disulfide oxidoreductase activity
MNHILNHP_00494 2e-18 L Psort location Cytoplasmic, score
MNHILNHP_00506 1.7e-12
MNHILNHP_00508 9.6e-96 lacA 2.3.1.79 S Transferase hexapeptide repeat
MNHILNHP_00509 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
MNHILNHP_00510 1e-25
MNHILNHP_00512 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MNHILNHP_00513 1.2e-154 KT YcbB domain
MNHILNHP_00514 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MNHILNHP_00515 3.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
MNHILNHP_00516 1.7e-154 EG EamA-like transporter family
MNHILNHP_00517 2.9e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MNHILNHP_00518 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MNHILNHP_00519 0.0 copA 3.6.3.54 P P-type ATPase
MNHILNHP_00520 4.5e-85
MNHILNHP_00522 2.3e-56
MNHILNHP_00523 2.5e-232 yjcE P Sodium proton antiporter
MNHILNHP_00525 1.5e-91
MNHILNHP_00526 9.5e-133 M domain protein
MNHILNHP_00527 1.4e-145 M domain protein
MNHILNHP_00528 4.3e-122 M domain protein
MNHILNHP_00529 2.8e-60 M domain protein
MNHILNHP_00530 7e-19
MNHILNHP_00531 8.2e-185 ampC V Beta-lactamase
MNHILNHP_00532 8.9e-218 arcA 3.5.3.6 E Arginine
MNHILNHP_00533 2.7e-79 argR K Regulates arginine biosynthesis genes
MNHILNHP_00534 1.1e-259 E Arginine ornithine antiporter
MNHILNHP_00535 6.1e-223 arcD U Amino acid permease
MNHILNHP_00536 3e-10
MNHILNHP_00537 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MNHILNHP_00538 2.2e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
MNHILNHP_00539 6e-108 tdk 2.7.1.21 F thymidine kinase
MNHILNHP_00540 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MNHILNHP_00541 2.5e-166 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MNHILNHP_00542 5.2e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MNHILNHP_00543 3.9e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MNHILNHP_00544 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MNHILNHP_00545 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MNHILNHP_00546 2e-192 yibE S overlaps another CDS with the same product name
MNHILNHP_00547 2.6e-130 yibF S overlaps another CDS with the same product name
MNHILNHP_00548 1e-232 pyrP F Permease
MNHILNHP_00549 2.6e-66 S Protein of unknown function (DUF3021)
MNHILNHP_00550 3e-75 K LytTr DNA-binding domain
MNHILNHP_00551 2.6e-94 K Acetyltransferase (GNAT) family
MNHILNHP_00552 4.7e-20
MNHILNHP_00553 7.9e-19 yhjX P Major Facilitator Superfamily
MNHILNHP_00554 8e-115 ybhL S Belongs to the BI1 family
MNHILNHP_00555 5.5e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
MNHILNHP_00556 4.6e-196 S Protein of unknown function (DUF3114)
MNHILNHP_00557 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MNHILNHP_00558 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MNHILNHP_00559 1.2e-105 yvdD 3.2.2.10 S Belongs to the LOG family
MNHILNHP_00560 9.1e-62 S Domain of unknown function (DUF4828)
MNHILNHP_00561 1.7e-190 mocA S Oxidoreductase
MNHILNHP_00562 2.2e-230 yfmL L DEAD DEAH box helicase
MNHILNHP_00564 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MNHILNHP_00565 1.8e-21
MNHILNHP_00566 5.8e-16
MNHILNHP_00567 1.3e-67 gtcA S Teichoic acid glycosylation protein
MNHILNHP_00568 6.1e-79 fld C Flavodoxin
MNHILNHP_00569 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
MNHILNHP_00570 7.8e-221 arcT 2.6.1.1 E Aminotransferase
MNHILNHP_00571 4e-254 E Arginine ornithine antiporter
MNHILNHP_00572 9e-281 yjeM E Amino Acid
MNHILNHP_00573 2.8e-149 yihY S Belongs to the UPF0761 family
MNHILNHP_00574 6.6e-34 S Protein of unknown function (DUF2922)
MNHILNHP_00575 4.9e-31
MNHILNHP_00576 1.4e-134 recX 2.4.1.337 GT4 S Regulatory protein RecX
MNHILNHP_00577 8.2e-145 cps1D M Domain of unknown function (DUF4422)
MNHILNHP_00578 1.9e-172 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MNHILNHP_00579 4.2e-118 rfbP 2.7.8.6 M Bacterial sugar transferase
MNHILNHP_00580 2.7e-73 cps3F
MNHILNHP_00581 3.6e-92 M transferase activity, transferring glycosyl groups
MNHILNHP_00582 2.3e-28 M biosynthesis protein
MNHILNHP_00583 5.7e-64 M Domain of unknown function (DUF4422)
MNHILNHP_00584 6.2e-80 M Core-2/I-Branching enzyme
MNHILNHP_00585 1.9e-151 ykoT GT2 M Glycosyl transferase family 2
MNHILNHP_00586 7.5e-72 S Acyltransferase family
MNHILNHP_00587 4.9e-32
MNHILNHP_00588 1.1e-211 glf 5.4.99.9 M UDP-galactopyranose mutase
MNHILNHP_00589 8.9e-230 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
MNHILNHP_00590 2.5e-75 waaB GT4 M Glycosyl transferases group 1
MNHILNHP_00591 1.4e-62 cps3I G Acyltransferase family
MNHILNHP_00592 2e-106 XK27_02070 S Nitroreductase family
MNHILNHP_00593 1.5e-82 K Transcriptional regulator, HxlR family
MNHILNHP_00594 9.8e-231
MNHILNHP_00595 6.5e-210 EGP Major facilitator Superfamily
MNHILNHP_00596 2e-255 pepC 3.4.22.40 E aminopeptidase
MNHILNHP_00597 8.4e-111 ylbE GM NAD dependent epimerase dehydratase family protein
MNHILNHP_00598 0.0 pepN 3.4.11.2 E aminopeptidase
MNHILNHP_00599 5.5e-48 K Transcriptional regulator
MNHILNHP_00600 1.9e-40 folT S ECF transporter, substrate-specific component
MNHILNHP_00601 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
MNHILNHP_00602 3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MNHILNHP_00603 7.4e-121 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MNHILNHP_00604 4.1e-162 2.7.7.65 T GGDEF domain
MNHILNHP_00605 1.7e-82
MNHILNHP_00606 3.4e-247 pgaC GT2 M Glycosyl transferase
MNHILNHP_00607 2.9e-137 T EAL domain
MNHILNHP_00608 7.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
MNHILNHP_00609 1.5e-59 yneR
MNHILNHP_00610 9.5e-102 qorB 1.6.5.2 GM NmrA-like family
MNHILNHP_00611 9.2e-44 akr5f 1.1.1.346 S reductase
MNHILNHP_00612 5.7e-104 akr5f 1.1.1.346 S reductase
MNHILNHP_00613 7.1e-145 K Transcriptional regulator
MNHILNHP_00614 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
MNHILNHP_00615 7.9e-156 ypuA S Protein of unknown function (DUF1002)
MNHILNHP_00616 1.1e-225 aadAT EK Aminotransferase, class I
MNHILNHP_00617 6.5e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MNHILNHP_00618 5.1e-153 tesE Q hydratase
MNHILNHP_00619 3.1e-75 S Alpha beta hydrolase
MNHILNHP_00620 4.1e-89 XK27_08850 J Aminoacyl-tRNA editing domain
MNHILNHP_00621 2.1e-70 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNHILNHP_00622 4.1e-192 V Beta-lactamase
MNHILNHP_00623 5.4e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MNHILNHP_00624 1.8e-21 yhiD S MgtC family
MNHILNHP_00625 7.3e-77 yhiD S MgtC family
MNHILNHP_00626 5.1e-110 S GyrI-like small molecule binding domain
MNHILNHP_00627 7.3e-110 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MNHILNHP_00628 3.2e-50 azlD E Branched-chain amino acid transport
MNHILNHP_00629 4.1e-119 azlC E azaleucine resistance protein AzlC
MNHILNHP_00630 6.3e-260 K Aminotransferase class I and II
MNHILNHP_00631 2.9e-99 S amidohydrolase
MNHILNHP_00632 6.2e-79 S amidohydrolase
MNHILNHP_00633 6.4e-30 L PFAM transposase IS200-family protein
MNHILNHP_00634 5.8e-184 S Phosphotransferase system, EIIC
MNHILNHP_00635 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MNHILNHP_00636 1.5e-181
MNHILNHP_00637 6.8e-62 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNHILNHP_00638 3.7e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MNHILNHP_00639 1.5e-82 manA 5.3.1.8 G mannose-6-phosphate isomerase
MNHILNHP_00640 9.1e-95 2.3.1.128 K acetyltransferase
MNHILNHP_00641 8.7e-187
MNHILNHP_00642 3.3e-17 K Transcriptional regulator, HxlR family
MNHILNHP_00643 3.6e-131 K Transcriptional regulatory protein, C-terminal domain protein
MNHILNHP_00644 3.9e-159 pstS P Phosphate
MNHILNHP_00645 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
MNHILNHP_00646 5.9e-155 pstA P Phosphate transport system permease protein PstA
MNHILNHP_00647 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MNHILNHP_00648 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
MNHILNHP_00649 5.8e-139
MNHILNHP_00651 5.5e-242 ydaM M Glycosyl transferase
MNHILNHP_00652 7.2e-222 G Glycosyl hydrolases family 8
MNHILNHP_00653 1.7e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MNHILNHP_00654 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MNHILNHP_00655 8.1e-241 ktrB P Potassium uptake protein
MNHILNHP_00656 7.7e-115 ktrA P domain protein
MNHILNHP_00657 2.4e-79 Q Methyltransferase
MNHILNHP_00658 4.8e-230 mntH P H( )-stimulated, divalent metal cation uptake system
MNHILNHP_00659 1.4e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MNHILNHP_00660 1.5e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MNHILNHP_00661 2.4e-95 S NADPH-dependent FMN reductase
MNHILNHP_00662 2.2e-177 MA20_14895 S Conserved hypothetical protein 698
MNHILNHP_00663 3e-133 I alpha/beta hydrolase fold
MNHILNHP_00664 1.6e-158 lsa S ABC transporter
MNHILNHP_00665 2e-100 lsa S ABC transporter
MNHILNHP_00666 3e-181 yfeX P Peroxidase
MNHILNHP_00667 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
MNHILNHP_00668 1.7e-259 ytjP 3.5.1.18 E Dipeptidase
MNHILNHP_00669 1.3e-216 uhpT EGP Major facilitator Superfamily
MNHILNHP_00670 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
MNHILNHP_00671 5.3e-131 ponA V Beta-lactamase enzyme family
MNHILNHP_00672 6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MNHILNHP_00673 3.7e-73
MNHILNHP_00674 4.6e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MNHILNHP_00675 1.1e-20
MNHILNHP_00676 4.2e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
MNHILNHP_00677 3.8e-170 L transposase, IS605 OrfB family
MNHILNHP_00678 5e-295 L PFAM plasmid pRiA4b ORF-3 family protein
MNHILNHP_00679 1.6e-204 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
MNHILNHP_00680 1.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MNHILNHP_00681 1.8e-156 mleR K LysR family
MNHILNHP_00682 6.3e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MNHILNHP_00683 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MNHILNHP_00684 3.4e-266 frdC 1.3.5.4 C FAD binding domain
MNHILNHP_00685 4.9e-252 yflS P Sodium:sulfate symporter transmembrane region
MNHILNHP_00686 1.1e-158 mleR K LysR family
MNHILNHP_00687 9.4e-253 yjjP S Putative threonine/serine exporter
MNHILNHP_00688 9.5e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
MNHILNHP_00689 8.5e-271 emrY EGP Major facilitator Superfamily
MNHILNHP_00690 4.6e-185 I Alpha beta
MNHILNHP_00691 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MNHILNHP_00692 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MNHILNHP_00694 4e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MNHILNHP_00695 1.9e-122 S Domain of unknown function (DUF4811)
MNHILNHP_00696 2.1e-269 lmrB EGP Major facilitator Superfamily
MNHILNHP_00697 3.1e-72 merR K MerR HTH family regulatory protein
MNHILNHP_00698 2.9e-57
MNHILNHP_00699 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MNHILNHP_00700 3.1e-220 S CAAX protease self-immunity
MNHILNHP_00701 3.6e-109 glnP P ABC transporter permease
MNHILNHP_00702 2.4e-110 gluC P ABC transporter permease
MNHILNHP_00703 3.3e-152 glnH ET ABC transporter
MNHILNHP_00704 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNHILNHP_00705 5.5e-83 usp1 T Belongs to the universal stress protein A family
MNHILNHP_00706 4.2e-108 S VIT family
MNHILNHP_00707 2.5e-116 S membrane
MNHILNHP_00708 5.5e-164 czcD P cation diffusion facilitator family transporter
MNHILNHP_00709 1.6e-123 sirR K iron dependent repressor
MNHILNHP_00710 1e-30 cspC K Cold shock protein
MNHILNHP_00711 4.4e-127 thrE S Putative threonine/serine exporter
MNHILNHP_00712 1e-81 S Threonine/Serine exporter, ThrE
MNHILNHP_00713 1.5e-118 lssY 3.6.1.27 I phosphatase
MNHILNHP_00714 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
MNHILNHP_00715 1.6e-274 lysP E amino acid
MNHILNHP_00716 9e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MNHILNHP_00722 3.9e-34 L PFAM Integrase catalytic region
MNHILNHP_00723 1.5e-144 S DUF218 domain
MNHILNHP_00724 0.0 ubiB S ABC1 family
MNHILNHP_00725 8.5e-246 yhdP S Transporter associated domain
MNHILNHP_00726 5e-75 copY K Copper transport repressor CopY TcrY
MNHILNHP_00727 5.5e-232 EGP Major facilitator Superfamily
MNHILNHP_00728 6.7e-70 yeaL S UPF0756 membrane protein
MNHILNHP_00729 2.2e-75 yphH S Cupin domain
MNHILNHP_00730 1.7e-68 C Flavodoxin
MNHILNHP_00731 2.2e-139 K LysR substrate binding domain protein
MNHILNHP_00732 7.2e-69 K Bacterial transcriptional regulator
MNHILNHP_00733 2.7e-130 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MNHILNHP_00734 6.3e-138 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MNHILNHP_00735 3.1e-47 G Xylose isomerase-like TIM barrel
MNHILNHP_00736 2e-13 higA K Helix-turn-helix XRE-family like proteins
MNHILNHP_00737 2.7e-13 higA K Helix-turn-helix XRE-family like proteins
MNHILNHP_00738 5.1e-220 uxaC 5.3.1.12 G glucuronate isomerase
MNHILNHP_00739 1.1e-217 uxuT G MFS/sugar transport protein
MNHILNHP_00740 2.6e-181 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MNHILNHP_00741 2.1e-211 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
MNHILNHP_00742 1.7e-53 kdgR K FCD domain
MNHILNHP_00743 1.7e-126 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
MNHILNHP_00744 3.1e-164 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MNHILNHP_00745 3.1e-68 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MNHILNHP_00746 2.5e-89 yqhA G Aldose 1-epimerase
MNHILNHP_00747 2.1e-125 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MNHILNHP_00748 3.7e-151 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MNHILNHP_00750 1.8e-98 S module of peptide synthetase
MNHILNHP_00751 9.2e-230 uxaC 5.3.1.12 G glucuronate isomerase
MNHILNHP_00752 7.8e-221 yjmB G MFS/sugar transport protein
MNHILNHP_00753 5.4e-96 exuR K Periplasmic binding protein domain
MNHILNHP_00754 3.6e-168 1.1.1.346 C Aldo keto reductase
MNHILNHP_00755 2.1e-39 gcvR T Belongs to the UPF0237 family
MNHILNHP_00756 1.3e-241 XK27_08635 S UPF0210 protein
MNHILNHP_00757 2.4e-53 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNHILNHP_00758 3.7e-77
MNHILNHP_00759 2.8e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
MNHILNHP_00760 6.8e-215 yttB EGP Major facilitator Superfamily
MNHILNHP_00761 2.6e-101
MNHILNHP_00762 1e-24
MNHILNHP_00763 2.5e-172 scrR K Transcriptional regulator, LacI family
MNHILNHP_00764 6.9e-237 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MNHILNHP_00765 9.2e-50 czrA K Transcriptional regulator, ArsR family
MNHILNHP_00766 2.5e-36
MNHILNHP_00767 0.0 yhcA V ABC transporter, ATP-binding protein
MNHILNHP_00768 1.3e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MNHILNHP_00769 1.2e-167 hrtB V ABC transporter permease
MNHILNHP_00770 1.8e-84 ygfC K transcriptional regulator (TetR family)
MNHILNHP_00771 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
MNHILNHP_00772 8.9e-287 mntH P H( )-stimulated, divalent metal cation uptake system
MNHILNHP_00773 0.0 tetP J Elongation factor G, domain IV
MNHILNHP_00774 2.8e-68 K Cro/C1-type HTH DNA-binding domain
MNHILNHP_00775 6.4e-32
MNHILNHP_00776 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MNHILNHP_00778 3.9e-213 yxiO S Vacuole effluxer Atg22 like
MNHILNHP_00779 6.3e-52 npp S type I phosphodiesterase nucleotide pyrophosphatase
MNHILNHP_00780 1.1e-130 npp S type I phosphodiesterase nucleotide pyrophosphatase
MNHILNHP_00781 5.1e-238 E amino acid
MNHILNHP_00782 3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MNHILNHP_00784 3.1e-217 yxjG_1 E methionine synthase, vitamin-B12 independent
MNHILNHP_00785 3.7e-35 S Cytochrome B5
MNHILNHP_00786 1.5e-74 elaA S Gnat family
MNHILNHP_00787 1.2e-120 GM NmrA-like family
MNHILNHP_00788 1.8e-50 hxlR K Transcriptional regulator, HxlR family
MNHILNHP_00789 3.3e-260 L Transposase
MNHILNHP_00790 5.9e-64 yeaO S Protein of unknown function, DUF488
MNHILNHP_00791 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MNHILNHP_00792 4.4e-203 3.1.3.1 S associated with various cellular activities
MNHILNHP_00793 7.9e-233 S Putative metallopeptidase domain
MNHILNHP_00794 1.4e-47
MNHILNHP_00795 0.0 pepO 3.4.24.71 O Peptidase family M13
MNHILNHP_00796 1.4e-105 K Helix-turn-helix XRE-family like proteins
MNHILNHP_00797 3.9e-87 ymdB S Macro domain protein
MNHILNHP_00798 2e-195 EGP Major facilitator Superfamily
MNHILNHP_00799 2.3e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNHILNHP_00800 3.1e-30 K helix_turn_helix, mercury resistance
MNHILNHP_00801 6.2e-10 K helix_turn_helix, mercury resistance
MNHILNHP_00802 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MNHILNHP_00803 1.4e-155 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MNHILNHP_00804 0.0 ysaB V FtsX-like permease family
MNHILNHP_00805 1.2e-132 macB2 V ABC transporter, ATP-binding protein
MNHILNHP_00806 2e-180 T PhoQ Sensor
MNHILNHP_00807 1.2e-123 K response regulator
MNHILNHP_00808 4.3e-155 ytbE 1.1.1.346 S Aldo keto reductase
MNHILNHP_00809 2.9e-134 pnuC H nicotinamide mononucleotide transporter
MNHILNHP_00810 1.1e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MNHILNHP_00811 1.1e-201
MNHILNHP_00812 2e-52
MNHILNHP_00813 9.1e-36
MNHILNHP_00814 4.5e-91 yxkA S Phosphatidylethanolamine-binding protein
MNHILNHP_00815 7e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
MNHILNHP_00816 2.5e-175 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
MNHILNHP_00817 1.1e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MNHILNHP_00818 6.9e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MNHILNHP_00819 5.4e-181 galR K Transcriptional regulator
MNHILNHP_00820 1.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
MNHILNHP_00821 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MNHILNHP_00822 1.4e-78 K AsnC family
MNHILNHP_00823 1.6e-79 uspA T universal stress protein
MNHILNHP_00824 3.7e-42 ltrA S Bacterial low temperature requirement A protein (LtrA)
MNHILNHP_00825 8.2e-57 ltrA S Bacterial low temperature requirement A protein (LtrA)
MNHILNHP_00826 9.9e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MNHILNHP_00827 2.5e-103 T Ion transport 2 domain protein
MNHILNHP_00828 0.0 S Bacterial membrane protein YfhO
MNHILNHP_00829 3.7e-205 G Transporter, major facilitator family protein
MNHILNHP_00830 6.2e-105 yvrI K sigma factor activity
MNHILNHP_00831 7.5e-59 ydiI Q Thioesterase superfamily
MNHILNHP_00832 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MNHILNHP_00833 2.2e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MNHILNHP_00834 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MNHILNHP_00835 2.8e-31 feoA P FeoA domain
MNHILNHP_00836 1.9e-144 sufC O FeS assembly ATPase SufC
MNHILNHP_00837 5.1e-240 sufD O FeS assembly protein SufD
MNHILNHP_00838 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MNHILNHP_00839 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
MNHILNHP_00840 1.2e-271 sufB O assembly protein SufB
MNHILNHP_00841 2.8e-57 yitW S Iron-sulfur cluster assembly protein
MNHILNHP_00842 5.2e-159 hipB K Helix-turn-helix
MNHILNHP_00843 3.4e-115 nreC K PFAM regulatory protein LuxR
MNHILNHP_00845 9.2e-39 S Cytochrome B5
MNHILNHP_00846 1e-153 yitU 3.1.3.104 S hydrolase
MNHILNHP_00847 3.7e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MNHILNHP_00848 1.5e-147 f42a O Band 7 protein
MNHILNHP_00849 3.9e-50 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
MNHILNHP_00850 2.4e-110 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
MNHILNHP_00851 2.6e-118 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MNHILNHP_00852 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MNHILNHP_00853 3.7e-185 galR K Periplasmic binding protein-like domain
MNHILNHP_00854 0.0 rafA 3.2.1.22 G alpha-galactosidase
MNHILNHP_00855 1.7e-106 L hmm pf00665
MNHILNHP_00856 2.1e-37 L PFAM Integrase catalytic region
MNHILNHP_00866 3.3e-142 L Belongs to the 'phage' integrase family
MNHILNHP_00867 1.2e-49 S Domain of unknown function (DUF4352)
MNHILNHP_00869 5.4e-19 E Zn peptidase
MNHILNHP_00870 7.9e-15 XK27_10050 K Peptidase S24-like
MNHILNHP_00872 5.4e-37
MNHILNHP_00874 8.4e-31
MNHILNHP_00876 1.9e-83 S Siphovirus Gp157
MNHILNHP_00877 1.4e-259 res L Helicase C-terminal domain protein
MNHILNHP_00878 4.6e-140 L AAA domain
MNHILNHP_00879 1.1e-92
MNHILNHP_00880 4e-147 S Bifunctional DNA primase/polymerase, N-terminal
MNHILNHP_00881 1.7e-232 S Virulence-associated protein E
MNHILNHP_00883 5.1e-57 S VRR_NUC
MNHILNHP_00889 7.3e-12
MNHILNHP_00894 3.6e-79 arpU S Phage transcriptional regulator, ArpU family
MNHILNHP_00895 1.7e-116 C Domain of unknown function (DUF4145)
MNHILNHP_00897 1e-67 L Terminase small subunit
MNHILNHP_00898 7e-218 S Phage terminase, large subunit
MNHILNHP_00899 7.7e-210 S Phage portal protein, SPP1 Gp6-like
MNHILNHP_00900 4.8e-143 S Phage Mu protein F like protein
MNHILNHP_00902 2.3e-65 S aminoacyl-tRNA ligase activity
MNHILNHP_00903 1.2e-115
MNHILNHP_00904 1.5e-46 S Phage gp6-like head-tail connector protein
MNHILNHP_00905 4.9e-19
MNHILNHP_00906 5.5e-43 S exonuclease activity
MNHILNHP_00907 2.1e-43
MNHILNHP_00908 2.3e-83 S Phage major tail protein 2
MNHILNHP_00909 4.2e-45 S Pfam:Phage_TAC_12
MNHILNHP_00910 4.6e-20
MNHILNHP_00911 3e-156 S peptidoglycan catabolic process
MNHILNHP_00912 1.1e-64 S Phage tail protein
MNHILNHP_00913 3.7e-265 G Major Facilitator
MNHILNHP_00914 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MNHILNHP_00915 3.6e-278 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
MNHILNHP_00916 1.3e-271 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
MNHILNHP_00917 3.6e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
MNHILNHP_00918 2.2e-72
MNHILNHP_00919 4e-75 K Transcriptional regulator, TetR family
MNHILNHP_00920 2.1e-12 K Transcriptional regulator, TetR family
MNHILNHP_00921 1.1e-13 steT_1 E amino acid
MNHILNHP_00923 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MNHILNHP_00924 8.5e-81
MNHILNHP_00925 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MNHILNHP_00926 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MNHILNHP_00927 5.8e-263 nox C NADH oxidase
MNHILNHP_00928 3e-87 hmpT S ECF-type riboflavin transporter, S component
MNHILNHP_00929 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
MNHILNHP_00930 5.9e-168 yvgN C Aldo keto reductase
MNHILNHP_00931 6.6e-136 puuD S peptidase C26
MNHILNHP_00932 1.6e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MNHILNHP_00933 2.6e-214 yfeO P Voltage gated chloride channel
MNHILNHP_00934 3.1e-226 sptS 2.7.13.3 T Histidine kinase
MNHILNHP_00935 3.3e-118 K response regulator
MNHILNHP_00936 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
MNHILNHP_00937 1e-71
MNHILNHP_00938 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MNHILNHP_00939 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MNHILNHP_00940 1.1e-256 malT G Major Facilitator
MNHILNHP_00941 1.1e-51 L Transposase IS200 like
MNHILNHP_00942 2.5e-185 L transposase, IS605 OrfB family
MNHILNHP_00945 3.5e-120 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MNHILNHP_00946 9.7e-142 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MNHILNHP_00947 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
MNHILNHP_00948 0.0 trxB2 1.8.1.9 C Thioredoxin domain
MNHILNHP_00949 2.2e-273 pipD E Dipeptidase
MNHILNHP_00950 1.5e-293 yjbQ P TrkA C-terminal domain protein
MNHILNHP_00951 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MNHILNHP_00952 4.8e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MNHILNHP_00953 9.3e-89
MNHILNHP_00954 7.3e-36
MNHILNHP_00955 2.1e-164 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MNHILNHP_00956 1.1e-134 epsB M biosynthesis protein
MNHILNHP_00957 5.8e-111 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MNHILNHP_00958 3.3e-102 rfbP M Bacterial sugar transferase
MNHILNHP_00959 2.1e-160 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MNHILNHP_00960 1.6e-100 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MNHILNHP_00961 1.5e-194 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MNHILNHP_00962 6.4e-111 M Glycosyl transferase 4-like domain
MNHILNHP_00963 1.2e-75 MA20_43635 M Capsular polysaccharide synthesis protein
MNHILNHP_00964 4.2e-125 GT2 M Glycosyltransferase like family 2
MNHILNHP_00965 4.5e-71 M Glycosyl transferase, family 2
MNHILNHP_00966 3.6e-92 S Psort location CytoplasmicMembrane, score 9.99
MNHILNHP_00967 6.4e-148 S polysaccharide biosynthetic process
MNHILNHP_00968 2.1e-213 glf 5.4.99.9 M UDP-galactopyranose mutase
MNHILNHP_00969 1.5e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MNHILNHP_00970 8.7e-84 L PFAM Integrase catalytic region
MNHILNHP_00971 1.4e-82
MNHILNHP_00972 1.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MNHILNHP_00973 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MNHILNHP_00974 1.1e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MNHILNHP_00975 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MNHILNHP_00976 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MNHILNHP_00977 1.8e-251 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MNHILNHP_00978 9.8e-67 yabR J RNA binding
MNHILNHP_00979 1.6e-55 divIC D Septum formation initiator
MNHILNHP_00980 2.1e-39 yabO J S4 domain protein
MNHILNHP_00981 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MNHILNHP_00982 1.3e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MNHILNHP_00983 1.1e-113 S (CBS) domain
MNHILNHP_00984 5.5e-144 tesE Q hydratase
MNHILNHP_00985 2.3e-242 codA 3.5.4.1 F cytosine deaminase
MNHILNHP_00986 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
MNHILNHP_00987 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
MNHILNHP_00988 9e-209 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MNHILNHP_00989 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MNHILNHP_00991 8.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MNHILNHP_00992 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
MNHILNHP_00993 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MNHILNHP_00994 5.6e-255 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MNHILNHP_00995 1.4e-164 glsA 3.5.1.2 E Belongs to the glutaminase family
MNHILNHP_00996 1.2e-233 EGP Sugar (and other) transporter
MNHILNHP_00997 2.3e-254 yfnA E Amino Acid
MNHILNHP_00998 2.2e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MNHILNHP_00999 1.4e-101 gmk2 2.7.4.8 F Guanylate kinase
MNHILNHP_01000 9.6e-82 zur P Belongs to the Fur family
MNHILNHP_01001 4e-17 3.2.1.14 GH18
MNHILNHP_01002 1e-148
MNHILNHP_01003 1.7e-38 pspC KT positive regulation of macromolecule biosynthetic process
MNHILNHP_01004 1.7e-93 K Transcriptional regulator (TetR family)
MNHILNHP_01005 1.8e-221 V domain protein
MNHILNHP_01006 7.9e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNHILNHP_01008 2.1e-33 S Transglycosylase associated protein
MNHILNHP_01009 4.6e-225 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MNHILNHP_01010 1.5e-126 3.1.3.73 G phosphoglycerate mutase
MNHILNHP_01011 2e-56 dedA S SNARE associated Golgi protein
MNHILNHP_01012 6.2e-52 dedA S SNARE associated Golgi protein
MNHILNHP_01013 0.0 helD 3.6.4.12 L DNA helicase
MNHILNHP_01014 3.7e-36 Q pyridine nucleotide-disulphide oxidoreductase
MNHILNHP_01015 1.1e-156 EG EamA-like transporter family
MNHILNHP_01016 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MNHILNHP_01017 1.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
MNHILNHP_01018 1.3e-218 S cog cog1373
MNHILNHP_01020 3.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MNHILNHP_01021 2.9e-104 L Transposase IS66 family
MNHILNHP_01022 1.1e-59 L Transposase IS66 family
MNHILNHP_01023 1e-23
MNHILNHP_01024 3.1e-101 V VanZ like family
MNHILNHP_01025 7.7e-231 cycA E Amino acid permease
MNHILNHP_01026 6.2e-84 perR P Belongs to the Fur family
MNHILNHP_01027 7.9e-258 EGP Major facilitator Superfamily
MNHILNHP_01028 6.7e-93 tag 3.2.2.20 L glycosylase
MNHILNHP_01029 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MNHILNHP_01030 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MNHILNHP_01031 2.9e-41
MNHILNHP_01032 9.2e-303 ytgP S Polysaccharide biosynthesis protein
MNHILNHP_01033 9.8e-29
MNHILNHP_01034 1.2e-28
MNHILNHP_01036 4.5e-17 K Cro/C1-type HTH DNA-binding domain
MNHILNHP_01037 1.7e-09
MNHILNHP_01038 7.2e-121 L hmm pf00665
MNHILNHP_01039 9.9e-62 L Helix-turn-helix domain
MNHILNHP_01042 5.9e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MNHILNHP_01043 3.4e-274 pepV 3.5.1.18 E dipeptidase PepV
MNHILNHP_01044 7.3e-86 uspA T Belongs to the universal stress protein A family
MNHILNHP_01045 1.5e-173 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MNHILNHP_01046 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
MNHILNHP_01047 2.5e-112
MNHILNHP_01048 2.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
MNHILNHP_01049 1.4e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MNHILNHP_01050 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MNHILNHP_01051 1.7e-260 yfnA E amino acid
MNHILNHP_01052 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MNHILNHP_01053 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MNHILNHP_01054 4.1e-40 ylqC S Belongs to the UPF0109 family
MNHILNHP_01055 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MNHILNHP_01056 5.1e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MNHILNHP_01057 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MNHILNHP_01058 1.1e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MNHILNHP_01059 0.0 smc D Required for chromosome condensation and partitioning
MNHILNHP_01060 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MNHILNHP_01061 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MNHILNHP_01062 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MNHILNHP_01063 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MNHILNHP_01064 0.0 yloV S DAK2 domain fusion protein YloV
MNHILNHP_01065 8.8e-57 asp S Asp23 family, cell envelope-related function
MNHILNHP_01066 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MNHILNHP_01067 2.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
MNHILNHP_01068 4.7e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MNHILNHP_01069 1.1e-161 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MNHILNHP_01070 0.0 KLT serine threonine protein kinase
MNHILNHP_01071 2.1e-129 stp 3.1.3.16 T phosphatase
MNHILNHP_01072 3.1e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MNHILNHP_01073 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MNHILNHP_01074 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MNHILNHP_01075 9.6e-209 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MNHILNHP_01076 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MNHILNHP_01077 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MNHILNHP_01078 4.2e-53
MNHILNHP_01079 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
MNHILNHP_01080 1.6e-76 argR K Regulates arginine biosynthesis genes
MNHILNHP_01081 3.4e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MNHILNHP_01082 1.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MNHILNHP_01083 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MNHILNHP_01084 6.5e-214 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MNHILNHP_01085 1.4e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MNHILNHP_01086 4.7e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MNHILNHP_01087 2.2e-70 yqhY S Asp23 family, cell envelope-related function
MNHILNHP_01088 1e-114 J 2'-5' RNA ligase superfamily
MNHILNHP_01089 1.5e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MNHILNHP_01090 8.9e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MNHILNHP_01091 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MNHILNHP_01092 2.4e-53 ysxB J Cysteine protease Prp
MNHILNHP_01093 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
MNHILNHP_01094 2.1e-103 K Transcriptional regulator
MNHILNHP_01097 8.2e-85 dut S Protein conserved in bacteria
MNHILNHP_01098 3.3e-181
MNHILNHP_01099 2.6e-150
MNHILNHP_01100 4.8e-51 S Iron-sulfur cluster assembly protein
MNHILNHP_01101 4.7e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MNHILNHP_01102 3e-78 S Fic/DOC family
MNHILNHP_01105 4.2e-29
MNHILNHP_01106 4.9e-08 V CAAX protease self-immunity
MNHILNHP_01109 2.2e-51 trwN GH23 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MNHILNHP_01111 2.8e-194 U type IV secretory pathway VirB4
MNHILNHP_01112 8.4e-29
MNHILNHP_01114 1.2e-68
MNHILNHP_01115 7.3e-234 U TraM recognition site of TraD and TraG
MNHILNHP_01120 2.1e-146 clpB O Belongs to the ClpA ClpB family
MNHILNHP_01123 8.3e-144 topA2 5.99.1.2 G Topoisomerase IA
MNHILNHP_01124 2.1e-51 L Protein of unknown function (DUF3991)
MNHILNHP_01125 1e-08 nrdH O Glutaredoxin
MNHILNHP_01128 2.3e-15 K ORF6N domain
MNHILNHP_01130 6.1e-31 XK27_00515 D Glucan-binding protein C
MNHILNHP_01132 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MNHILNHP_01133 9.4e-38 yheA S Belongs to the UPF0342 family
MNHILNHP_01134 9.1e-220 yhaO L Ser Thr phosphatase family protein
MNHILNHP_01135 0.0 L AAA domain
MNHILNHP_01136 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MNHILNHP_01138 4.1e-77 hit FG histidine triad
MNHILNHP_01139 5.1e-136 ecsA V ABC transporter, ATP-binding protein
MNHILNHP_01140 2.8e-216 ecsB U ABC transporter
MNHILNHP_01141 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MNHILNHP_01142 6.2e-15 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
MNHILNHP_01143 1.3e-64 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
MNHILNHP_01144 2.6e-11 glsA 3.5.1.2 E Belongs to the glutaminase family
MNHILNHP_01145 1.1e-56 ytzB S Small secreted protein
MNHILNHP_01146 1.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MNHILNHP_01147 1.1e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MNHILNHP_01148 2.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MNHILNHP_01149 1.4e-119 ybhL S Belongs to the BI1 family
MNHILNHP_01150 4.3e-69 yoaK S Protein of unknown function (DUF1275)
MNHILNHP_01151 1e-15 yoaK S Protein of unknown function (DUF1275)
MNHILNHP_01152 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MNHILNHP_01153 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MNHILNHP_01154 6.5e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MNHILNHP_01155 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MNHILNHP_01156 1e-222 dnaB L replication initiation and membrane attachment
MNHILNHP_01157 4.3e-172 dnaI L Primosomal protein DnaI
MNHILNHP_01158 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MNHILNHP_01159 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MNHILNHP_01160 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MNHILNHP_01161 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MNHILNHP_01162 8.5e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MNHILNHP_01163 0.0 S Bacterial membrane protein, YfhO
MNHILNHP_01164 1.1e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MNHILNHP_01165 4.5e-168 I alpha/beta hydrolase fold
MNHILNHP_01166 5e-215 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MNHILNHP_01167 1.4e-119 tcyB E ABC transporter
MNHILNHP_01168 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNHILNHP_01169 6.2e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MNHILNHP_01170 2.5e-266 pepC 3.4.22.40 E Peptidase C1-like family
MNHILNHP_01171 1.4e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MNHILNHP_01172 1.9e-49 HA62_12640 S GCN5-related N-acetyl-transferase
MNHILNHP_01173 2.3e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MNHILNHP_01174 2.9e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MNHILNHP_01175 1.4e-204 yacL S domain protein
MNHILNHP_01176 3.9e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MNHILNHP_01177 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MNHILNHP_01178 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MNHILNHP_01179 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MNHILNHP_01180 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MNHILNHP_01181 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
MNHILNHP_01182 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MNHILNHP_01183 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MNHILNHP_01184 1.6e-224 aadAT EK Aminotransferase, class I
MNHILNHP_01185 1.2e-74 M Glycosyl transferase family group 2
MNHILNHP_01186 3.1e-128 M Glycosyl transferase family group 2
MNHILNHP_01187 4.9e-207 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MNHILNHP_01188 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
MNHILNHP_01189 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MNHILNHP_01190 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MNHILNHP_01191 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MNHILNHP_01192 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MNHILNHP_01193 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MNHILNHP_01194 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MNHILNHP_01195 2.9e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MNHILNHP_01196 1.3e-33 ywzB S Protein of unknown function (DUF1146)
MNHILNHP_01197 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MNHILNHP_01198 1.9e-178 mbl D Cell shape determining protein MreB Mrl
MNHILNHP_01199 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MNHILNHP_01200 1e-31 S Protein of unknown function (DUF2969)
MNHILNHP_01201 1.1e-220 rodA D Belongs to the SEDS family
MNHILNHP_01202 1.4e-47 gcvH E glycine cleavage
MNHILNHP_01203 3.4e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MNHILNHP_01204 1.5e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MNHILNHP_01205 4.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MNHILNHP_01206 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
MNHILNHP_01207 1.4e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MNHILNHP_01208 2.2e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MNHILNHP_01209 2.2e-50 maa 2.3.1.79 S Maltose O-acetyltransferase
MNHILNHP_01210 9.2e-29 maa 2.3.1.79 S Maltose O-acetyltransferase
MNHILNHP_01211 7.3e-155 ytbE 1.1.1.346 S Aldo keto reductase
MNHILNHP_01212 1.4e-203 araR K Transcriptional regulator
MNHILNHP_01213 4.3e-83 usp6 T universal stress protein
MNHILNHP_01214 1.7e-45
MNHILNHP_01215 7.9e-233 rarA L recombination factor protein RarA
MNHILNHP_01216 5.1e-84 yueI S Protein of unknown function (DUF1694)
MNHILNHP_01217 4.6e-21
MNHILNHP_01218 1.3e-148 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
MNHILNHP_01219 2.2e-270 ywfO S HD domain protein
MNHILNHP_01220 7.9e-146 yxeH S hydrolase
MNHILNHP_01221 9e-48
MNHILNHP_01222 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MNHILNHP_01223 2.7e-239 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MNHILNHP_01224 1.2e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MNHILNHP_01225 8e-127 znuB U ABC 3 transport family
MNHILNHP_01226 5e-122 fhuC P ABC transporter
MNHILNHP_01227 6.9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
MNHILNHP_01228 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MNHILNHP_01229 6.8e-37 veg S Biofilm formation stimulator VEG
MNHILNHP_01230 2.8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MNHILNHP_01231 8e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MNHILNHP_01232 3.5e-154 tatD L hydrolase, TatD family
MNHILNHP_01233 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MNHILNHP_01234 1.2e-160 yunF F Protein of unknown function DUF72
MNHILNHP_01236 4e-130 cobB K SIR2 family
MNHILNHP_01237 1.9e-175
MNHILNHP_01238 9.7e-228 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MNHILNHP_01239 1.8e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MNHILNHP_01240 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MNHILNHP_01241 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MNHILNHP_01242 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MNHILNHP_01243 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MNHILNHP_01244 6.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MNHILNHP_01245 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MNHILNHP_01246 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MNHILNHP_01247 2.9e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MNHILNHP_01248 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MNHILNHP_01249 8e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MNHILNHP_01250 1.2e-217 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MNHILNHP_01251 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MNHILNHP_01252 5.6e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MNHILNHP_01253 1.3e-226 mtnE 2.6.1.83 E Aminotransferase
MNHILNHP_01254 6.2e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MNHILNHP_01255 0.0 uup S ABC transporter, ATP-binding protein
MNHILNHP_01256 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MNHILNHP_01258 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MNHILNHP_01259 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MNHILNHP_01260 5.3e-81 S Aminoacyl-tRNA editing domain
MNHILNHP_01261 2.6e-302 ybeC E amino acid
MNHILNHP_01262 0.0 ydaO E amino acid
MNHILNHP_01263 2.7e-39
MNHILNHP_01265 1.5e-118 yrkL S Flavodoxin-like fold
MNHILNHP_01266 1.5e-52
MNHILNHP_01267 2.4e-16 S Domain of unknown function (DUF4767)
MNHILNHP_01268 4.1e-29 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MNHILNHP_01269 3.4e-48
MNHILNHP_01270 2.6e-205 nrnB S DHHA1 domain
MNHILNHP_01271 3.4e-225 S Uncharacterized protein conserved in bacteria (DUF2325)
MNHILNHP_01272 2.4e-248 brnQ U Component of the transport system for branched-chain amino acids
MNHILNHP_01273 1.1e-104 NU mannosyl-glycoprotein
MNHILNHP_01274 5.6e-141 S Putative ABC-transporter type IV
MNHILNHP_01275 1.9e-273 S ABC transporter, ATP-binding protein
MNHILNHP_01276 4.9e-18 K Helix-turn-helix domain
MNHILNHP_01279 1.6e-90 S PAS domain
MNHILNHP_01280 8e-71 macB_3 V FtsX-like permease family
MNHILNHP_01281 5.4e-175 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MNHILNHP_01282 3.9e-246 emrY EGP Major facilitator Superfamily
MNHILNHP_01283 1.4e-118 ywfI S Chlorite dismutase
MNHILNHP_01284 3.6e-257 gor 1.8.1.7 C Glutathione reductase
MNHILNHP_01285 1.1e-41 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
MNHILNHP_01286 3.9e-19 arsB 1.20.4.1 P Sodium Bile acid symporter family
MNHILNHP_01289 1.7e-63 L Belongs to the 'phage' integrase family
MNHILNHP_01290 1.7e-13 L Belongs to the 'phage' integrase family
MNHILNHP_01291 8.7e-36 3.1.21.3 V Type I restriction modification DNA specificity domain
MNHILNHP_01292 1.8e-148 V Type I restriction-modification system methyltransferase subunit()
MNHILNHP_01293 8.8e-19 D nuclear chromosome segregation
MNHILNHP_01294 5e-135 cjaA ET ABC transporter substrate-binding protein
MNHILNHP_01295 3.7e-118 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNHILNHP_01296 2.1e-96 P ABC transporter permease
MNHILNHP_01297 7.1e-97 papP P ABC transporter, permease protein
MNHILNHP_01300 3.1e-70
MNHILNHP_01303 9.4e-11 T PFAM SpoVT AbrB
MNHILNHP_01304 1e-22 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MNHILNHP_01307 7.5e-65 ruvB 3.6.4.12 L four-way junction helicase activity
MNHILNHP_01315 4.9e-52
MNHILNHP_01316 4.5e-112 frnE Q DSBA-like thioredoxin domain
MNHILNHP_01317 1.3e-162 I alpha/beta hydrolase fold
MNHILNHP_01318 8.5e-20 K Helix-turn-helix XRE-family like proteins
MNHILNHP_01319 3.3e-35 S Phage derived protein Gp49-like (DUF891)
MNHILNHP_01321 8.9e-41 yrvD S Pfam:DUF1049
MNHILNHP_01322 2.4e-150 3.1.3.102, 3.1.3.104 S hydrolase
MNHILNHP_01323 1.1e-89 ntd 2.4.2.6 F Nucleoside
MNHILNHP_01324 2e-18
MNHILNHP_01325 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
MNHILNHP_01326 4.7e-114 yviA S Protein of unknown function (DUF421)
MNHILNHP_01327 4.5e-71 S Protein of unknown function (DUF3290)
MNHILNHP_01328 2.3e-41 ybaN S Protein of unknown function (DUF454)
MNHILNHP_01329 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNHILNHP_01330 1.6e-157 endA V DNA/RNA non-specific endonuclease
MNHILNHP_01331 6.6e-254 yifK E Amino acid permease
MNHILNHP_01333 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MNHILNHP_01334 2.3e-229 N Uncharacterized conserved protein (DUF2075)
MNHILNHP_01335 5.1e-122 S SNARE associated Golgi protein
MNHILNHP_01336 0.0 uvrA3 L excinuclease ABC, A subunit
MNHILNHP_01337 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MNHILNHP_01338 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MNHILNHP_01339 2.1e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MNHILNHP_01340 7.8e-160 dprA LU DNA protecting protein DprA
MNHILNHP_01341 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MNHILNHP_01342 2e-163 lacX 5.1.3.3 G Aldose 1-epimerase
MNHILNHP_01343 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MNHILNHP_01344 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MNHILNHP_01345 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MNHILNHP_01346 8.1e-79 F NUDIX domain
MNHILNHP_01347 8.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
MNHILNHP_01348 2.7e-67 yqkB S Belongs to the HesB IscA family
MNHILNHP_01349 5.6e-26
MNHILNHP_01351 6.1e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MNHILNHP_01352 3.7e-61 asp S Asp23 family, cell envelope-related function
MNHILNHP_01353 1e-24
MNHILNHP_01354 8e-94
MNHILNHP_01355 1.6e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MNHILNHP_01356 4.9e-182 K Transcriptional regulator, LacI family
MNHILNHP_01357 3.1e-232 gntT EG Gluconate
MNHILNHP_01358 6.5e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MNHILNHP_01359 1.1e-95 K Acetyltransferase (GNAT) domain
MNHILNHP_01360 1.9e-41
MNHILNHP_01361 2.4e-22
MNHILNHP_01362 2.2e-44
MNHILNHP_01363 4.3e-57 yhaI S Protein of unknown function (DUF805)
MNHILNHP_01364 6.5e-85 S Short repeat of unknown function (DUF308)
MNHILNHP_01365 2.2e-78 S Psort location Cytoplasmic, score
MNHILNHP_01366 1.2e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
MNHILNHP_01367 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
MNHILNHP_01368 5.3e-153 yeaE S Aldo keto
MNHILNHP_01369 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
MNHILNHP_01370 1.2e-235 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MNHILNHP_01371 3.9e-147 xth 3.1.11.2 L exodeoxyribonuclease III
MNHILNHP_01372 7.3e-84 lytE M LysM domain protein
MNHILNHP_01373 0.0 oppD EP Psort location Cytoplasmic, score
MNHILNHP_01374 2e-42 lytE M LysM domain protein
MNHILNHP_01375 1.2e-158 sufD O Uncharacterized protein family (UPF0051)
MNHILNHP_01376 1.7e-110 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MNHILNHP_01377 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MNHILNHP_01378 4.2e-63 lmrB EGP Major facilitator Superfamily
MNHILNHP_01379 2.4e-157 lmrB EGP Major facilitator Superfamily
MNHILNHP_01380 1.6e-94 2.3.1.128 K Acetyltransferase (GNAT) domain
MNHILNHP_01381 1.7e-96 S N-acetylmuramoyl-L-alanine amidase activity
MNHILNHP_01382 3.3e-74 S Bacteriophage holin family
MNHILNHP_01385 1e-99 S peptidoglycan catabolic process
MNHILNHP_01386 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
MNHILNHP_01387 4.3e-172 malR K Transcriptional regulator, LacI family
MNHILNHP_01388 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MNHILNHP_01389 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MNHILNHP_01390 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MNHILNHP_01391 2e-103 wecD3 K PFAM GCN5-related N-acetyltransferase
MNHILNHP_01393 0.0 clpL O associated with various cellular activities
MNHILNHP_01394 7.8e-32
MNHILNHP_01395 1.8e-215 patA 2.6.1.1 E Aminotransferase
MNHILNHP_01396 1.6e-172 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNHILNHP_01397 5e-75 osmC O OsmC-like protein
MNHILNHP_01398 1.1e-84 K FR47-like protein
MNHILNHP_01399 2.5e-53 L An automated process has identified a potential problem with this gene model
MNHILNHP_01400 1.2e-08 2.7.13.3 T GHKL domain
MNHILNHP_01402 2.4e-259 S Putative peptidoglycan binding domain
MNHILNHP_01403 3.8e-22
MNHILNHP_01404 7.8e-214 bacI V MacB-like periplasmic core domain
MNHILNHP_01405 2.8e-128 V ABC transporter
MNHILNHP_01406 2.8e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MNHILNHP_01407 4.4e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MNHILNHP_01408 1.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MNHILNHP_01409 1.9e-149 E Glyoxalase-like domain
MNHILNHP_01410 7.5e-155 glcU U sugar transport
MNHILNHP_01411 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
MNHILNHP_01412 2.9e-96 S reductase
MNHILNHP_01414 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MNHILNHP_01415 6.5e-179 ABC-SBP S ABC transporter
MNHILNHP_01416 2e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MNHILNHP_01417 4.7e-214 htrA 3.4.21.107 O serine protease
MNHILNHP_01418 1.1e-152 vicX 3.1.26.11 S domain protein
MNHILNHP_01419 7.8e-149 yycI S YycH protein
MNHILNHP_01420 2.4e-245 yycH S YycH protein
MNHILNHP_01421 0.0 vicK 2.7.13.3 T Histidine kinase
MNHILNHP_01422 8.3e-128 K response regulator
MNHILNHP_01424 2.2e-307 lmrA 3.6.3.44 V ABC transporter
MNHILNHP_01425 6.8e-72 K helix_turn_helix multiple antibiotic resistance protein
MNHILNHP_01427 5.7e-96 Z012_01130 S Fic/DOC family
MNHILNHP_01429 2e-155 S Polyphosphate nucleotide phosphotransferase, PPK2 family
MNHILNHP_01430 9.1e-61
MNHILNHP_01431 9e-207 yttB EGP Major facilitator Superfamily
MNHILNHP_01432 4.1e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MNHILNHP_01433 2e-74 rplI J Binds to the 23S rRNA
MNHILNHP_01434 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MNHILNHP_01435 6.4e-53 deoR K sugar-binding domain protein
MNHILNHP_01436 2.2e-18 deoR K sugar-binding domain protein
MNHILNHP_01437 4e-47 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MNHILNHP_01438 8.4e-32 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MNHILNHP_01439 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MNHILNHP_01440 3.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MNHILNHP_01441 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MNHILNHP_01442 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MNHILNHP_01443 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MNHILNHP_01444 1.3e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MNHILNHP_01445 1.7e-34 yaaA S S4 domain protein YaaA
MNHILNHP_01446 2.6e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MNHILNHP_01447 1.2e-249 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MNHILNHP_01448 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MNHILNHP_01449 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MNHILNHP_01450 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MNHILNHP_01451 3e-131 jag S R3H domain protein
MNHILNHP_01452 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MNHILNHP_01453 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MNHILNHP_01454 0.0 asnB 6.3.5.4 E Asparagine synthase
MNHILNHP_01455 1.7e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MNHILNHP_01456 1.4e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
MNHILNHP_01457 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MNHILNHP_01458 2.5e-14 2.3.1.183 M Acetyltransferase GNAT family
MNHILNHP_01459 9.2e-49 2.3.1.183 M Acetyltransferase GNAT family
MNHILNHP_01460 4.3e-107 yvyE 3.4.13.9 S YigZ family
MNHILNHP_01461 9.5e-250 comFA L Helicase C-terminal domain protein
MNHILNHP_01462 1.1e-93 comFC S Competence protein
MNHILNHP_01463 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MNHILNHP_01464 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MNHILNHP_01465 6.6e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MNHILNHP_01466 7.7e-31 KT PspC domain protein
MNHILNHP_01467 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MNHILNHP_01468 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MNHILNHP_01469 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MNHILNHP_01470 1.1e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MNHILNHP_01471 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MNHILNHP_01472 1.7e-136 yrjD S LUD domain
MNHILNHP_01473 1.3e-292 lutB C 4Fe-4S dicluster domain
MNHILNHP_01474 7.8e-168 lutA C Cysteine-rich domain
MNHILNHP_01475 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MNHILNHP_01476 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MNHILNHP_01477 2.9e-162 aatB ET PFAM extracellular solute-binding protein, family 3
MNHILNHP_01478 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
MNHILNHP_01479 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MNHILNHP_01480 2.5e-77 L transposase and inactivated derivatives, IS30 family
MNHILNHP_01481 2.3e-177 S FRG
MNHILNHP_01482 8.2e-212 yfnA E Amino Acid
MNHILNHP_01483 3.2e-65 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MNHILNHP_01484 1.4e-54 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MNHILNHP_01485 5.3e-64 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MNHILNHP_01486 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MNHILNHP_01487 1.1e-297 mco Q Multicopper oxidase
MNHILNHP_01488 1.4e-126 L PFAM Integrase catalytic region
MNHILNHP_01489 8.4e-136 L Belongs to the 'phage' integrase family
MNHILNHP_01490 2e-10
MNHILNHP_01491 1.8e-160
MNHILNHP_01492 1.1e-79 K SIR2-like domain
MNHILNHP_01493 3.4e-71 L Resolvase, N terminal domain
MNHILNHP_01494 3.3e-39 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNHILNHP_01495 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MNHILNHP_01496 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MNHILNHP_01497 2e-158 htpX O Belongs to the peptidase M48B family
MNHILNHP_01498 7e-93 lemA S LemA family
MNHILNHP_01499 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MNHILNHP_01500 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MNHILNHP_01501 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MNHILNHP_01502 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MNHILNHP_01503 1.7e-156 3.2.1.55 GH51 G Right handed beta helix region
MNHILNHP_01504 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MNHILNHP_01505 7.3e-116 srtA 3.4.22.70 M sortase family
MNHILNHP_01506 9.7e-166 S Alpha/beta hydrolase of unknown function (DUF915)
MNHILNHP_01507 5.4e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MNHILNHP_01508 4.6e-41 rpmE2 J Ribosomal protein L31
MNHILNHP_01509 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MNHILNHP_01510 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MNHILNHP_01511 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MNHILNHP_01512 5.2e-53 ywiB S Domain of unknown function (DUF1934)
MNHILNHP_01513 2.6e-51 L transposase, IS605 OrfB family
MNHILNHP_01514 7.2e-34 T Toxin-antitoxin system, toxin component, MazF family
MNHILNHP_01515 8.9e-37
MNHILNHP_01516 1.1e-06 D nuclear chromosome segregation
MNHILNHP_01517 0.0 snf 2.7.11.1 KL domain protein
MNHILNHP_01518 4.1e-144 ywqE 3.1.3.48 GM PHP domain protein
MNHILNHP_01519 2.1e-205 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MNHILNHP_01520 0.0 sbcC L Putative exonuclease SbcCD, C subunit
MNHILNHP_01521 2e-17 L nuclease
MNHILNHP_01522 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
MNHILNHP_01523 2.8e-70
MNHILNHP_01524 4.4e-103 fic D Fic/DOC family
MNHILNHP_01525 2.3e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MNHILNHP_01526 4.4e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MNHILNHP_01527 7.9e-31
MNHILNHP_01528 1.1e-147
MNHILNHP_01529 2.7e-24
MNHILNHP_01530 2.3e-230 L Integrase core domain
MNHILNHP_01531 6.5e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MNHILNHP_01532 2.4e-56 K transcriptional regulator PadR family
MNHILNHP_01533 1.2e-82 XK27_06920 S Protein of unknown function (DUF1700)
MNHILNHP_01534 1.6e-132 S Putative adhesin
MNHILNHP_01535 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MNHILNHP_01536 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNHILNHP_01537 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MNHILNHP_01538 3.4e-35 nrdH O Glutaredoxin
MNHILNHP_01539 1e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MNHILNHP_01540 6.2e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MNHILNHP_01541 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MNHILNHP_01542 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MNHILNHP_01543 2.8e-38 S Protein of unknown function (DUF2508)
MNHILNHP_01544 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MNHILNHP_01545 2.9e-51 yaaQ S Cyclic-di-AMP receptor
MNHILNHP_01546 1.4e-181 holB 2.7.7.7 L DNA polymerase III
MNHILNHP_01547 3.1e-43 yabA L Involved in initiation control of chromosome replication
MNHILNHP_01548 6.4e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MNHILNHP_01549 1.4e-133 fat 3.1.2.21 I Acyl-ACP thioesterase
MNHILNHP_01550 1.3e-45 GT2,GT4 LM gp58-like protein
MNHILNHP_01552 4.8e-12
MNHILNHP_01553 1.8e-17 S Bacteriophage holin family
MNHILNHP_01554 7.7e-185 M lysozyme activity
MNHILNHP_01555 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
MNHILNHP_01556 5.6e-65 esbA S Family of unknown function (DUF5322)
MNHILNHP_01557 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MNHILNHP_01558 2.2e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MNHILNHP_01559 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
MNHILNHP_01560 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MNHILNHP_01561 0.0 FbpA K Fibronectin-binding protein
MNHILNHP_01562 1.6e-158 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNHILNHP_01563 2.1e-160 degV S EDD domain protein, DegV family
MNHILNHP_01564 1.1e-89
MNHILNHP_01565 1.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MNHILNHP_01566 8.7e-156 gspA M family 8
MNHILNHP_01567 2.8e-154 S Alpha beta hydrolase
MNHILNHP_01568 1.5e-94 K Acetyltransferase (GNAT) domain
MNHILNHP_01569 5.8e-149 L Initiator Replication protein
MNHILNHP_01570 1.3e-94
MNHILNHP_01571 0.0 uvrA2 L ABC transporter
MNHILNHP_01572 3.1e-104 L Integrase
MNHILNHP_01573 1.7e-33 S RelB antitoxin
MNHILNHP_01574 7.9e-45
MNHILNHP_01576 3.4e-209
MNHILNHP_01577 7e-59 soj D AAA domain
MNHILNHP_01578 3.4e-09
MNHILNHP_01579 3.3e-100 L Helix-turn-helix domain
MNHILNHP_01580 1.3e-123 L hmm pf00665
MNHILNHP_01581 6.6e-37 L PFAM Integrase catalytic region
MNHILNHP_01582 5.1e-87 yhbO 3.5.1.124 S Intracellular protease
MNHILNHP_01583 6e-252 pgi 5.3.1.9 G Belongs to the GPI family
MNHILNHP_01584 5e-93 hxlB 5.3.1.27 M 6-phospho 3-hexuloisomerase
MNHILNHP_01585 1.3e-108 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
MNHILNHP_01586 1.5e-68 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNHILNHP_01587 3.5e-76 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNHILNHP_01588 2.8e-106 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNHILNHP_01590 2.4e-23
MNHILNHP_01591 1.1e-15 S Phage gp6-like head-tail connector protein
MNHILNHP_01592 2.2e-189 S Caudovirus prohead serine protease
MNHILNHP_01593 1.1e-140 S Phage portal protein
MNHILNHP_01594 7.5e-199 terL S overlaps another CDS with the same product name
MNHILNHP_01595 1.9e-25 terS L Phage terminase, small subunit
MNHILNHP_01596 2.4e-32 L HNH endonuclease
MNHILNHP_01597 1.9e-16 S Phage head-tail joining protein
MNHILNHP_01599 4.9e-95 S Phage plasmid primase, P4
MNHILNHP_01600 8.5e-47 L Bifunctional DNA primase/polymerase, N-terminal
MNHILNHP_01604 2.8e-07 S Helix-turn-helix domain
MNHILNHP_01605 1.4e-09 K Helix-turn-helix XRE-family like proteins
MNHILNHP_01606 1.3e-55 sip L Belongs to the 'phage' integrase family
MNHILNHP_01607 1.6e-134 K response regulator
MNHILNHP_01608 2.6e-272 yclK 2.7.13.3 T Histidine kinase
MNHILNHP_01609 4.1e-153 glcU U sugar transport
MNHILNHP_01610 2.8e-47 L transposase IS116 IS110 IS902 family protein
MNHILNHP_01611 3.8e-70 yqeY S YqeY-like protein
MNHILNHP_01612 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MNHILNHP_01613 1.1e-262 glnPH2 P ABC transporter permease
MNHILNHP_01614 3.8e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNHILNHP_01615 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MNHILNHP_01616 9.3e-166 yniA G Phosphotransferase enzyme family
MNHILNHP_01617 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MNHILNHP_01618 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MNHILNHP_01619 9.4e-50
MNHILNHP_01620 1.1e-127 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MNHILNHP_01621 1.4e-178 prmA J Ribosomal protein L11 methyltransferase
MNHILNHP_01622 7.5e-58
MNHILNHP_01624 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MNHILNHP_01626 1.8e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MNHILNHP_01627 1.2e-274 pipD E Dipeptidase
MNHILNHP_01628 7.1e-63
MNHILNHP_01629 4e-14
MNHILNHP_01630 2.5e-103
MNHILNHP_01631 1.8e-135 V ABC transporter
MNHILNHP_01632 2.6e-211 EGP Major facilitator Superfamily
MNHILNHP_01633 1.5e-256 G PTS system Galactitol-specific IIC component
MNHILNHP_01634 9.8e-23 1.6.5.5 C Zinc-binding dehydrogenase
MNHILNHP_01635 5e-85 1.6.5.5 C Zinc-binding dehydrogenase
MNHILNHP_01636 3.5e-160
MNHILNHP_01637 1e-72 K Transcriptional regulator
MNHILNHP_01638 2e-172 D Alpha beta
MNHILNHP_01639 6.4e-52 ypaA S Protein of unknown function (DUF1304)
MNHILNHP_01640 0.0 yjcE P Sodium proton antiporter
MNHILNHP_01641 1.6e-52 yvlA
MNHILNHP_01642 8.6e-111 P Cobalt transport protein
MNHILNHP_01643 1.9e-248 cbiO1 S ABC transporter, ATP-binding protein
MNHILNHP_01644 7.9e-97 S ABC-type cobalt transport system, permease component
MNHILNHP_01645 3.3e-133 S membrane transporter protein
MNHILNHP_01646 4e-113 IQ KR domain
MNHILNHP_01647 2e-09 IQ KR domain
MNHILNHP_01650 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
MNHILNHP_01651 6.6e-279 L Transposase IS66 family
MNHILNHP_01653 5e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MNHILNHP_01654 2.5e-158 rrmA 2.1.1.187 H Methyltransferase
MNHILNHP_01655 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MNHILNHP_01656 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MNHILNHP_01657 1.2e-10 S Protein of unknown function (DUF4044)
MNHILNHP_01658 1.7e-57
MNHILNHP_01659 3.1e-77 mraZ K Belongs to the MraZ family
MNHILNHP_01660 1.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MNHILNHP_01661 1.3e-55 ftsL D Cell division protein FtsL
MNHILNHP_01662 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MNHILNHP_01663 2.2e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MNHILNHP_01664 1.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MNHILNHP_01665 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MNHILNHP_01666 2.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MNHILNHP_01667 7.3e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MNHILNHP_01668 3.5e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MNHILNHP_01669 2.1e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MNHILNHP_01670 3.2e-40 yggT S YGGT family
MNHILNHP_01671 8.4e-145 ylmH S S4 domain protein
MNHILNHP_01672 3e-35 divIVA D DivIVA domain protein
MNHILNHP_01673 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MNHILNHP_01674 4.2e-32 cspA K Cold shock protein
MNHILNHP_01675 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MNHILNHP_01677 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MNHILNHP_01678 1.6e-216 iscS 2.8.1.7 E Aminotransferase class V
MNHILNHP_01679 7.5e-58 XK27_04120 S Putative amino acid metabolism
MNHILNHP_01680 3.4e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MNHILNHP_01681 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MNHILNHP_01682 4.9e-117 S Repeat protein
MNHILNHP_01683 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MNHILNHP_01684 2.6e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MNHILNHP_01685 1.1e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MNHILNHP_01686 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
MNHILNHP_01687 6.9e-245 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MNHILNHP_01688 7e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MNHILNHP_01689 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MNHILNHP_01690 1e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MNHILNHP_01691 4.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MNHILNHP_01692 7.7e-219 patA 2.6.1.1 E Aminotransferase
MNHILNHP_01693 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MNHILNHP_01694 8.5e-84 KT Putative sugar diacid recognition
MNHILNHP_01695 5.5e-218 EG GntP family permease
MNHILNHP_01696 6e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MNHILNHP_01697 2.2e-57
MNHILNHP_01699 3.8e-130 mltD CBM50 M NlpC P60 family protein
MNHILNHP_01700 5.7e-29
MNHILNHP_01701 6.7e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
MNHILNHP_01702 9.8e-32 ykzG S Belongs to the UPF0356 family
MNHILNHP_01703 4.8e-79
MNHILNHP_01704 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MNHILNHP_01705 2.8e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MNHILNHP_01706 5.3e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MNHILNHP_01707 1.7e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MNHILNHP_01708 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
MNHILNHP_01709 3.7e-45 yktA S Belongs to the UPF0223 family
MNHILNHP_01710 3.8e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MNHILNHP_01711 0.0 typA T GTP-binding protein TypA
MNHILNHP_01712 3.5e-222 ftsW D Belongs to the SEDS family
MNHILNHP_01713 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MNHILNHP_01714 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MNHILNHP_01715 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MNHILNHP_01716 2.1e-196 ylbL T Belongs to the peptidase S16 family
MNHILNHP_01717 5.8e-80 comEA L Competence protein ComEA
MNHILNHP_01718 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
MNHILNHP_01719 0.0 comEC S Competence protein ComEC
MNHILNHP_01720 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
MNHILNHP_01721 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
MNHILNHP_01722 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MNHILNHP_01723 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MNHILNHP_01724 3.5e-163 S Tetratricopeptide repeat
MNHILNHP_01725 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MNHILNHP_01726 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MNHILNHP_01727 4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MNHILNHP_01728 6.1e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
MNHILNHP_01729 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MNHILNHP_01730 3e-52 L transposase, IS605 OrfB family
MNHILNHP_01731 1.3e-14 K Cro/C1-type HTH DNA-binding domain
MNHILNHP_01735 1.3e-263 dtpT U amino acid peptide transporter
MNHILNHP_01736 1.1e-150 yjjH S Calcineurin-like phosphoesterase
MNHILNHP_01739 7.7e-112
MNHILNHP_01740 8.5e-249 EGP Major facilitator Superfamily
MNHILNHP_01741 1e-301 aspT P Predicted Permease Membrane Region
MNHILNHP_01742 2.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MNHILNHP_01743 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
MNHILNHP_01744 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MNHILNHP_01745 5.7e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MNHILNHP_01746 0.0 yhgF K Tex-like protein N-terminal domain protein
MNHILNHP_01747 6.8e-83 ydcK S Belongs to the SprT family
MNHILNHP_01749 5.9e-135 M domain protein
MNHILNHP_01750 9.6e-190 UW LPXTG-motif cell wall anchor domain protein
MNHILNHP_01751 4.1e-180 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MNHILNHP_01752 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MNHILNHP_01753 1.2e-168 T Calcineurin-like phosphoesterase superfamily domain
MNHILNHP_01754 1.8e-223 mdtG EGP Major facilitator Superfamily
MNHILNHP_01755 8.9e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MNHILNHP_01756 1.7e-85 yxjG_1 E methionine synthase, vitamin-B12 independent
MNHILNHP_01757 6.4e-113 yxjG_1 E methionine synthase, vitamin-B12 independent
MNHILNHP_01758 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MNHILNHP_01759 3.2e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MNHILNHP_01760 0.0 lacZ 3.2.1.23 G -beta-galactosidase
MNHILNHP_01761 0.0 lacS G Transporter
MNHILNHP_01762 3e-187 lacR K Transcriptional regulator
MNHILNHP_01763 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
MNHILNHP_01764 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
MNHILNHP_01765 8.5e-34
MNHILNHP_01766 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MNHILNHP_01767 3.3e-33 copZ C Heavy-metal-associated domain
MNHILNHP_01768 2e-92 dps P Belongs to the Dps family
MNHILNHP_01769 6.8e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MNHILNHP_01770 3.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
MNHILNHP_01771 1.4e-44 5.1.1.13 M Asp/Glu/Hydantoin racemase
MNHILNHP_01772 2.2e-21 5.1.1.13 M Asp/Glu/Hydantoin racemase
MNHILNHP_01773 1.7e-149 L Recombinase
MNHILNHP_01774 4.1e-227 L Recombinase zinc beta ribbon domain
MNHILNHP_01775 9.7e-20
MNHILNHP_01776 1.2e-54 S Bacteriophage holin family
MNHILNHP_01777 1.9e-54 S Phage head-tail joining protein
MNHILNHP_01778 8e-42 S Phage gp6-like head-tail connector protein
MNHILNHP_01779 2.3e-159 S Phage capsid family
MNHILNHP_01780 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MNHILNHP_01781 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
MNHILNHP_01782 1e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MNHILNHP_01783 1.2e-102 pncA Q Isochorismatase family
MNHILNHP_01784 5.7e-09 S Domain of unknown function (DUF4767)
MNHILNHP_01785 2.5e-40 S Acyltransferase family
MNHILNHP_01786 1.8e-34 S Peptidase_C39 like family
MNHILNHP_01787 1.8e-56 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MNHILNHP_01788 6e-67 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MNHILNHP_01789 4.1e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MNHILNHP_01790 1.3e-223 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MNHILNHP_01791 3.3e-163 yueF S AI-2E family transporter
MNHILNHP_01792 2.4e-24
MNHILNHP_01793 1.2e-54 M repeat protein
MNHILNHP_01794 1.9e-66 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MNHILNHP_01795 6.1e-57
MNHILNHP_01797 3e-80 L Bacterial dnaA protein
MNHILNHP_01798 2.4e-174 L PFAM Integrase, catalytic core
MNHILNHP_01799 2e-159 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MNHILNHP_01800 1.4e-43 hxlR K Transcriptional regulator, HxlR family
MNHILNHP_01802 4.2e-163 S Putative peptidoglycan binding domain
MNHILNHP_01803 1.4e-92 yciB M ErfK YbiS YcfS YnhG
MNHILNHP_01804 1.6e-10
MNHILNHP_01805 5.1e-43
MNHILNHP_01806 1e-104 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MNHILNHP_01808 1.4e-07 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
MNHILNHP_01809 1e-12 L Resolvase, N terminal domain
MNHILNHP_01810 3.3e-39 ykuJ S Protein of unknown function (DUF1797)
MNHILNHP_01811 1.1e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MNHILNHP_01812 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
MNHILNHP_01813 1.1e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MNHILNHP_01814 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MNHILNHP_01815 2.7e-39 ptsH G phosphocarrier protein HPR
MNHILNHP_01816 3.2e-26
MNHILNHP_01817 0.0 clpE O Belongs to the ClpA ClpB family
MNHILNHP_01818 1.7e-100 S Pfam:DUF3816
MNHILNHP_01819 1.8e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
MNHILNHP_01820 8.4e-117
MNHILNHP_01821 6.8e-156 V ABC transporter, ATP-binding protein
MNHILNHP_01822 6e-64 gntR1 K Transcriptional regulator, GntR family
MNHILNHP_01823 1e-109 S Peptidase, M23
MNHILNHP_01824 1.5e-55 trxA O Belongs to the thioredoxin family
MNHILNHP_01825 6.6e-131 terC P membrane
MNHILNHP_01826 6.3e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MNHILNHP_01827 2.8e-168 corA P CorA-like Mg2+ transporter protein
MNHILNHP_01828 6.2e-279 pipD E Dipeptidase
MNHILNHP_01829 2.1e-241 pbuX F xanthine permease
MNHILNHP_01830 1.7e-249 nhaC C Na H antiporter NhaC
MNHILNHP_01831 4e-49 S C4-dicarboxylate anaerobic carrier
MNHILNHP_01832 2.7e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
MNHILNHP_01833 2.3e-38
MNHILNHP_01834 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MNHILNHP_01835 8.4e-207 gldA 1.1.1.6 C dehydrogenase
MNHILNHP_01836 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
MNHILNHP_01837 1.4e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MNHILNHP_01838 5.8e-60 S Double zinc ribbon
MNHILNHP_01839 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MNHILNHP_01840 2e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MNHILNHP_01841 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MNHILNHP_01842 4.8e-177 yagE E amino acid
MNHILNHP_01843 3e-51 yagE E amino acid
MNHILNHP_01844 3.4e-85 dps P Belongs to the Dps family
MNHILNHP_01845 0.0 pacL 3.6.3.8 P P-type ATPase
MNHILNHP_01846 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MNHILNHP_01847 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MNHILNHP_01848 8.6e-20 cnrT EG PFAM EamA-like transporter family
MNHILNHP_01849 4e-17 cnrT EG PFAM EamA-like transporter family
MNHILNHP_01850 9.8e-51 S Domain of unknown function (DUF4430)
MNHILNHP_01851 5.9e-73 S ECF transporter, substrate-specific component
MNHILNHP_01852 2.9e-19 S PFAM Archaeal ATPase
MNHILNHP_01853 3.2e-179 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MNHILNHP_01854 1.7e-17 K Winged helix DNA-binding domain
MNHILNHP_01855 2e-287 lmrA V ABC transporter, ATP-binding protein
MNHILNHP_01856 0.0 yfiC V ABC transporter
MNHILNHP_01857 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
MNHILNHP_01858 2.6e-269 pipD E Dipeptidase
MNHILNHP_01859 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MNHILNHP_01860 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
MNHILNHP_01861 1.2e-36 S Uncharacterised protein family (UPF0236)
MNHILNHP_01862 1.9e-26 L PFAM transposase IS200-family protein
MNHILNHP_01863 6.3e-37 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MNHILNHP_01864 6.5e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MNHILNHP_01865 5.7e-264 glnP P ABC transporter
MNHILNHP_01866 7.2e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNHILNHP_01867 4.7e-220 cycA E Amino acid permease
MNHILNHP_01868 1.3e-218 nupG F Nucleoside transporter
MNHILNHP_01869 1.7e-170 rihC 3.2.2.1 F Nucleoside
MNHILNHP_01870 1.1e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
MNHILNHP_01871 1.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MNHILNHP_01872 8.7e-144 noc K Belongs to the ParB family
MNHILNHP_01873 1e-139 soj D Sporulation initiation inhibitor
MNHILNHP_01874 4.2e-153 spo0J K Belongs to the ParB family
MNHILNHP_01875 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
MNHILNHP_01876 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MNHILNHP_01877 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
MNHILNHP_01878 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MNHILNHP_01879 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MNHILNHP_01880 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
MNHILNHP_01881 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MNHILNHP_01882 4e-170 deoR K sugar-binding domain protein
MNHILNHP_01883 2e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MNHILNHP_01884 3.8e-125 K response regulator
MNHILNHP_01885 8.3e-202 hpk31 2.7.13.3 T Histidine kinase
MNHILNHP_01886 2.3e-138 azlC E AzlC protein
MNHILNHP_01887 1.6e-52 azlD S branched-chain amino acid
MNHILNHP_01888 2.9e-124 K LysR substrate binding domain
MNHILNHP_01889 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MNHILNHP_01890 2.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MNHILNHP_01891 2.1e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MNHILNHP_01892 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MNHILNHP_01893 2.8e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MNHILNHP_01894 3.7e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
MNHILNHP_01895 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MNHILNHP_01896 5.3e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MNHILNHP_01897 6.6e-174 K AI-2E family transporter
MNHILNHP_01898 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MNHILNHP_01899 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MNHILNHP_01900 2.5e-127 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MNHILNHP_01901 2.7e-24 K helix_turn_helix, arabinose operon control protein
MNHILNHP_01902 3.4e-187 thrC 4.2.3.1 E Threonine synthase
MNHILNHP_01903 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MNHILNHP_01904 1.4e-100 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MNHILNHP_01905 2.1e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MNHILNHP_01906 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MNHILNHP_01907 1.3e-251 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MNHILNHP_01908 2.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MNHILNHP_01909 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNHILNHP_01910 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNHILNHP_01911 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MNHILNHP_01912 5.8e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MNHILNHP_01913 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MNHILNHP_01914 8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MNHILNHP_01915 4.6e-296 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MNHILNHP_01916 2e-241 purD 6.3.4.13 F Belongs to the GARS family
MNHILNHP_01917 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MNHILNHP_01918 1.8e-166
MNHILNHP_01919 3.5e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MNHILNHP_01920 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MNHILNHP_01921 5.1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MNHILNHP_01922 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
MNHILNHP_01923 3.1e-113 yjbH Q Thioredoxin
MNHILNHP_01924 6.8e-267 pipD E Dipeptidase
MNHILNHP_01925 1.8e-195 coiA 3.6.4.12 S Competence protein
MNHILNHP_01926 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MNHILNHP_01927 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MNHILNHP_01928 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MNHILNHP_01929 2.5e-294 L Transposase IS66 family
MNHILNHP_01930 4.6e-66 XK27_01125 L PFAM IS66 Orf2 family protein
MNHILNHP_01955 3.1e-85 L Belongs to the 'phage' integrase family
MNHILNHP_01957 4.4e-09
MNHILNHP_01959 1.1e-56 L Resolvase, N terminal domain
MNHILNHP_01960 6.9e-12 L Resolvase, N terminal domain
MNHILNHP_01961 1.2e-08 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
MNHILNHP_01963 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MNHILNHP_01964 3.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MNHILNHP_01965 1e-259 G Major Facilitator
MNHILNHP_01966 1.3e-174 K Transcriptional regulator, LacI family
MNHILNHP_01967 2.7e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MNHILNHP_01968 2.4e-101 nqr 1.5.1.36 S reductase
MNHILNHP_01969 5e-200 XK27_09615 S reductase
MNHILNHP_01970 5.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MNHILNHP_01972 3.3e-132 L Belongs to the 'phage' integrase family
MNHILNHP_01973 1.2e-15
MNHILNHP_01974 2.3e-66 repB EP Plasmid replication protein
MNHILNHP_01976 4.1e-134 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MNHILNHP_01980 3.4e-23 D nuclear chromosome segregation
MNHILNHP_01981 6.8e-22 K Helix-turn-helix domain
MNHILNHP_01984 1.8e-31
MNHILNHP_01985 1e-108 S CAAX protease self-immunity
MNHILNHP_01986 1.9e-43
MNHILNHP_01988 5.9e-67
MNHILNHP_01989 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MNHILNHP_01990 1.1e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MNHILNHP_01991 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
MNHILNHP_01992 1.8e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MNHILNHP_01993 5.4e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
MNHILNHP_01994 4.8e-213 folP 2.5.1.15 H dihydropteroate synthase
MNHILNHP_01995 6.7e-43
MNHILNHP_01996 4.8e-39
MNHILNHP_01998 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MNHILNHP_01999 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MNHILNHP_02000 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MNHILNHP_02001 1.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
MNHILNHP_02002 6.6e-81 uspA T universal stress protein
MNHILNHP_02003 0.0 tetP J elongation factor G
MNHILNHP_02004 2.9e-165 GK ROK family
MNHILNHP_02005 2e-239 brnQ U Component of the transport system for branched-chain amino acids
MNHILNHP_02006 2.3e-136 aroD S Serine hydrolase (FSH1)
MNHILNHP_02007 1.2e-80 yagE E amino acid
MNHILNHP_02008 1.1e-61 yagE E amino acid
MNHILNHP_02009 4.3e-58 yagE E amino acid
MNHILNHP_02010 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MNHILNHP_02011 1.1e-169 yjjC V ABC transporter
MNHILNHP_02012 6.5e-293 M Exporter of polyketide antibiotics
MNHILNHP_02013 9.6e-115 K Transcriptional regulator
MNHILNHP_02014 1.4e-39 L Integrase core domain
MNHILNHP_02015 1.7e-60 L Resolvase, N terminal domain
MNHILNHP_02016 8.6e-33 S Phage derived protein Gp49-like (DUF891)
MNHILNHP_02017 2.4e-25 K Helix-turn-helix domain
MNHILNHP_02018 1.8e-46 S Acetyltransferase (GNAT) domain
MNHILNHP_02019 1.5e-78 L An automated process has identified a potential problem with this gene model
MNHILNHP_02020 8.5e-75 K Copper transport repressor CopY TcrY
MNHILNHP_02021 0.0 copB 3.6.3.4 P P-type ATPase
MNHILNHP_02023 5.6e-183 comGA NU Type II IV secretion system protein
MNHILNHP_02024 1.5e-181 comGB NU type II secretion system
MNHILNHP_02025 7.1e-47 comGC U competence protein ComGC
MNHILNHP_02026 5.4e-77 NU general secretion pathway protein
MNHILNHP_02027 3.2e-41
MNHILNHP_02028 1e-67
MNHILNHP_02030 1e-142 ytxK 2.1.1.72 L N-6 DNA Methylase
MNHILNHP_02031 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MNHILNHP_02032 4.7e-111 S Calcineurin-like phosphoesterase
MNHILNHP_02033 6.6e-93 yutD S Protein of unknown function (DUF1027)
MNHILNHP_02034 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MNHILNHP_02035 2.8e-101 S Protein of unknown function (DUF1461)
MNHILNHP_02036 1.6e-109 dedA S SNARE-like domain protein
MNHILNHP_02037 3.3e-234 mepA V MATE efflux family protein
MNHILNHP_02038 9.9e-55 K Transcriptional regulator, ArsR family
MNHILNHP_02039 7.4e-95 P Cadmium resistance transporter
MNHILNHP_02040 1.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
MNHILNHP_02041 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MNHILNHP_02042 4.1e-181 ABC-SBP S ABC transporter
MNHILNHP_02043 2.3e-73 M PFAM NLP P60 protein
MNHILNHP_02044 6e-74 S Protein of unknown function (DUF3278)
MNHILNHP_02045 7.8e-123 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MNHILNHP_02046 1.4e-95 yqeG S HAD phosphatase, family IIIA
MNHILNHP_02047 2.4e-217 yqeH S Ribosome biogenesis GTPase YqeH
MNHILNHP_02048 1.9e-47 yhbY J RNA-binding protein
MNHILNHP_02049 6.9e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MNHILNHP_02050 2.8e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MNHILNHP_02051 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MNHILNHP_02052 1.1e-135 yqeM Q Methyltransferase
MNHILNHP_02053 6.9e-209 ylbM S Belongs to the UPF0348 family
MNHILNHP_02054 4.9e-99 yceD S Uncharacterized ACR, COG1399
MNHILNHP_02055 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MNHILNHP_02056 2e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
MNHILNHP_02057 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MNHILNHP_02058 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
MNHILNHP_02059 2.2e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MNHILNHP_02060 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
MNHILNHP_02061 1.1e-239 hemL 5.4.3.8 H Aminotransferase class-III
MNHILNHP_02062 6.2e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
MNHILNHP_02063 2.6e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MNHILNHP_02064 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MNHILNHP_02065 7e-59 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
MNHILNHP_02066 2.7e-240 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
MNHILNHP_02067 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
MNHILNHP_02068 6.8e-103 cbiQ P Cobalt transport protein
MNHILNHP_02069 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
MNHILNHP_02070 1e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
MNHILNHP_02071 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
MNHILNHP_02072 8.1e-108 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
MNHILNHP_02073 3.3e-176 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
MNHILNHP_02074 2.8e-97 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
MNHILNHP_02075 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
MNHILNHP_02076 4.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
MNHILNHP_02077 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
MNHILNHP_02078 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
MNHILNHP_02079 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
MNHILNHP_02080 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
MNHILNHP_02081 3.8e-109 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
MNHILNHP_02082 4.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MNHILNHP_02083 7.3e-205 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
MNHILNHP_02084 6.1e-170 cobD 4.1.1.81 E Aminotransferase class I and II
MNHILNHP_02085 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
MNHILNHP_02086 2.5e-115 XK27_04590 S NADPH-dependent FMN reductase
MNHILNHP_02087 2.2e-73 fld C Flavodoxin
MNHILNHP_02088 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
MNHILNHP_02089 5.9e-68 P Cadmium resistance transporter
MNHILNHP_02090 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
MNHILNHP_02091 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
MNHILNHP_02092 3e-54 pduU E BMC
MNHILNHP_02093 1.9e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MNHILNHP_02094 2.1e-202 pduQ C Iron-containing alcohol dehydrogenase
MNHILNHP_02095 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
MNHILNHP_02096 4.5e-77 pduO S Haem-degrading
MNHILNHP_02097 1e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
MNHILNHP_02098 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
MNHILNHP_02099 1.3e-79 S Putative propanediol utilisation
MNHILNHP_02100 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
MNHILNHP_02101 7.8e-40 pduA_4 CQ BMC
MNHILNHP_02102 1.8e-56 pduK CQ BMC
MNHILNHP_02103 2.6e-45 pduH S Dehydratase medium subunit
MNHILNHP_02104 8.1e-308 pduG D Diol dehydratase reactivase ATPase-like domain
MNHILNHP_02105 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
MNHILNHP_02106 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
MNHILNHP_02107 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
MNHILNHP_02108 2.7e-134 pduB E BMC
MNHILNHP_02109 1.6e-37 pduA_4 CQ BMC
MNHILNHP_02110 8.3e-159 K helix_turn_helix, arabinose operon control protein
MNHILNHP_02111 3.6e-138 eutJ E Hsp70 protein
MNHILNHP_02112 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MNHILNHP_02113 1.4e-159
MNHILNHP_02114 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
MNHILNHP_02115 2.6e-160 S AI-2E family transporter
MNHILNHP_02116 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
MNHILNHP_02117 1.1e-77 yybA 2.3.1.57 K Transcriptional regulator
MNHILNHP_02118 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
MNHILNHP_02119 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
MNHILNHP_02120 1.7e-154 ypdB V (ABC) transporter
MNHILNHP_02121 1.9e-237 yhdP S Transporter associated domain
MNHILNHP_02122 2.7e-82 nrdI F Belongs to the NrdI family
MNHILNHP_02123 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
MNHILNHP_02124 4.4e-190 yeaN P Transporter, major facilitator family protein
MNHILNHP_02125 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MNHILNHP_02126 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MNHILNHP_02127 2.3e-28
MNHILNHP_02128 0.0 lacS G Transporter
MNHILNHP_02129 6.7e-59 L transposase IS116 IS110 IS902 family protein
MNHILNHP_02130 5.3e-121 S Alpha beta hydrolase
MNHILNHP_02131 3.7e-216 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MNHILNHP_02132 1.3e-97
MNHILNHP_02134 1.3e-122 yciB M ErfK YbiS YcfS YnhG
MNHILNHP_02135 1.2e-260 S Putative peptidoglycan binding domain
MNHILNHP_02136 1.3e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MNHILNHP_02137 7.4e-33 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNHILNHP_02144 1.7e-39
MNHILNHP_02145 8.6e-202 amtB P ammonium transporter
MNHILNHP_02146 2.6e-247 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
MNHILNHP_02147 2.5e-83 yvbK 3.1.3.25 K GNAT family
MNHILNHP_02148 9.6e-92
MNHILNHP_02149 2.2e-122 pnb C nitroreductase
MNHILNHP_02150 3.1e-75 ogt 2.1.1.63 L Methyltransferase
MNHILNHP_02151 3.8e-149 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
MNHILNHP_02152 9.5e-39 S Cytochrome B5
MNHILNHP_02153 1.6e-37 L Helix-turn-helix domain
MNHILNHP_02154 6.7e-122 O Zinc-dependent metalloprotease
MNHILNHP_02155 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MNHILNHP_02156 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
MNHILNHP_02159 4.3e-13
MNHILNHP_02160 5.7e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
MNHILNHP_02161 3.2e-53 ltrA S Bacterial low temperature requirement A protein (LtrA)
MNHILNHP_02162 7e-56 wecD3 K PFAM GCN5-related N-acetyltransferase
MNHILNHP_02163 3.1e-28 wecD3 K PFAM GCN5-related N-acetyltransferase
MNHILNHP_02164 2.1e-79
MNHILNHP_02165 5.3e-115 M Lysin motif
MNHILNHP_02166 3e-52 L transposase, IS605 OrfB family
MNHILNHP_02167 4.6e-48 L Integrase
MNHILNHP_02169 2.7e-36 K Transcriptional regulator, ArsR family
MNHILNHP_02170 8.3e-62 P Cadmium resistance transporter
MNHILNHP_02171 5.9e-49 bamA GM domain, Protein
MNHILNHP_02172 4e-63
MNHILNHP_02173 1.5e-53
MNHILNHP_02174 1.3e-33
MNHILNHP_02175 1.8e-206 potD P ABC transporter
MNHILNHP_02176 6.5e-140 potC P ABC transporter permease
MNHILNHP_02177 4.5e-146 potB P ABC transporter permease
MNHILNHP_02178 4.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MNHILNHP_02179 2.6e-106 L Uncharacterized conserved protein (DUF2075)
MNHILNHP_02180 0.0 L PLD-like domain
MNHILNHP_02182 1.7e-31 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MNHILNHP_02183 2.9e-210 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MNHILNHP_02184 6.8e-30 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MNHILNHP_02185 1.1e-138 S Belongs to the UPF0246 family
MNHILNHP_02186 1.4e-136 S Membrane
MNHILNHP_02187 6.8e-74 4.4.1.5 E Glyoxalase
MNHILNHP_02188 1.2e-51 L PFAM Integrase catalytic region
MNHILNHP_02189 1.3e-72 L PFAM Integrase catalytic region
MNHILNHP_02190 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MNHILNHP_02191 3.4e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MNHILNHP_02192 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
MNHILNHP_02193 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MNHILNHP_02194 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MNHILNHP_02195 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
MNHILNHP_02196 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MNHILNHP_02197 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MNHILNHP_02198 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MNHILNHP_02199 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
MNHILNHP_02200 1.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MNHILNHP_02201 8e-122 radC L DNA repair protein
MNHILNHP_02202 1.7e-179 mreB D cell shape determining protein MreB
MNHILNHP_02203 3.5e-152 mreC M Involved in formation and maintenance of cell shape
MNHILNHP_02204 8.7e-93 mreD M rod shape-determining protein MreD
MNHILNHP_02205 3.2e-102 glnP P ABC transporter permease
MNHILNHP_02206 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MNHILNHP_02207 1.9e-158 aatB ET ABC transporter substrate-binding protein
MNHILNHP_02208 8.1e-227 ymfF S Peptidase M16 inactive domain protein
MNHILNHP_02209 2.5e-247 ymfH S Peptidase M16
MNHILNHP_02210 1.7e-137 ymfM S Helix-turn-helix domain
MNHILNHP_02211 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MNHILNHP_02212 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
MNHILNHP_02213 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MNHILNHP_02214 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
MNHILNHP_02215 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MNHILNHP_02216 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MNHILNHP_02217 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MNHILNHP_02218 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MNHILNHP_02219 2.2e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MNHILNHP_02220 6.2e-31 yajC U Preprotein translocase
MNHILNHP_02221 7.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MNHILNHP_02222 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MNHILNHP_02223 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MNHILNHP_02224 4.1e-43 yrzL S Belongs to the UPF0297 family
MNHILNHP_02225 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MNHILNHP_02226 6.1e-48 yrzB S Belongs to the UPF0473 family
MNHILNHP_02227 2.7e-86 cvpA S Colicin V production protein
MNHILNHP_02228 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MNHILNHP_02229 6.1e-54 trxA O Belongs to the thioredoxin family
MNHILNHP_02230 6.6e-96 yslB S Protein of unknown function (DUF2507)
MNHILNHP_02231 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MNHILNHP_02232 3.7e-105 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MNHILNHP_02233 7.6e-94 S Phosphoesterase
MNHILNHP_02234 1.1e-74 ykuL S (CBS) domain
MNHILNHP_02235 3.1e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
MNHILNHP_02236 3.4e-147 ykuT M mechanosensitive ion channel
MNHILNHP_02237 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MNHILNHP_02238 2.5e-24
MNHILNHP_02239 3.6e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MNHILNHP_02240 2.1e-180 ccpA K catabolite control protein A
MNHILNHP_02241 1.1e-131
MNHILNHP_02242 5.9e-132 yebC K Transcriptional regulatory protein
MNHILNHP_02243 1.8e-196 EGP Major facilitator Superfamily
MNHILNHP_02244 1e-37 D Antitoxin component of a toxin-antitoxin (TA) module
MNHILNHP_02245 4.6e-49 S ParE toxin of type II toxin-antitoxin system, parDE
MNHILNHP_02246 1.4e-93 ywlG S Belongs to the UPF0340 family
MNHILNHP_02247 2.3e-159 spoU 2.1.1.185 J Methyltransferase
MNHILNHP_02248 4.1e-37 S Uncharacterised protein family (UPF0236)
MNHILNHP_02249 1.3e-78 L Replication protein
MNHILNHP_02251 3.3e-22
MNHILNHP_02255 3.4e-250 mmuP E amino acid
MNHILNHP_02256 1.2e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MNHILNHP_02257 9.5e-18
MNHILNHP_02258 1.8e-15 3.2.1.18 GH33 M Rib/alpha-like repeat
MNHILNHP_02259 4.2e-59 S Uncharacterised protein family (UPF0236)
MNHILNHP_02260 4.9e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MNHILNHP_02261 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MNHILNHP_02262 2e-26
MNHILNHP_02264 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MNHILNHP_02265 5.2e-23 K transcriptional regulator PadR family
MNHILNHP_02266 2.1e-31 L Transposase IS66 family
MNHILNHP_02267 6.3e-18 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNHILNHP_02268 2.3e-48 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MNHILNHP_02269 9.6e-45 UW LPXTG-motif cell wall anchor domain protein
MNHILNHP_02270 3.9e-68 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MNHILNHP_02271 5.5e-45 yitW S Pfam:DUF59
MNHILNHP_02272 1.6e-169 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MNHILNHP_02273 3.7e-279 arlS 2.7.13.3 T Histidine kinase
MNHILNHP_02274 1.5e-121 K response regulator
MNHILNHP_02275 4.4e-42 L PFAM Integrase catalytic region
MNHILNHP_02276 1.8e-150 S Hydrolases of the alpha beta superfamily
MNHILNHP_02277 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
MNHILNHP_02278 4.4e-77 ctsR K Belongs to the CtsR family
MNHILNHP_02279 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MNHILNHP_02280 1e-110 K Bacterial regulatory proteins, tetR family
MNHILNHP_02281 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNHILNHP_02282 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNHILNHP_02283 2.3e-199 ykiI
MNHILNHP_02284 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
MNHILNHP_02285 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MNHILNHP_02286 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MNHILNHP_02287 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MNHILNHP_02288 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MNHILNHP_02289 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MNHILNHP_02290 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
MNHILNHP_02291 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MNHILNHP_02292 2.1e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MNHILNHP_02293 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MNHILNHP_02294 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MNHILNHP_02295 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MNHILNHP_02296 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MNHILNHP_02297 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
MNHILNHP_02298 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MNHILNHP_02299 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MNHILNHP_02300 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MNHILNHP_02301 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MNHILNHP_02302 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MNHILNHP_02303 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MNHILNHP_02304 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MNHILNHP_02305 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MNHILNHP_02306 6.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MNHILNHP_02307 2.9e-24 rpmD J Ribosomal protein L30
MNHILNHP_02308 1.5e-63 rplO J Binds to the 23S rRNA
MNHILNHP_02309 1.7e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MNHILNHP_02310 4.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MNHILNHP_02311 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MNHILNHP_02312 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MNHILNHP_02313 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MNHILNHP_02314 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MNHILNHP_02315 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MNHILNHP_02316 1.1e-62 rplQ J Ribosomal protein L17
MNHILNHP_02317 1.1e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNHILNHP_02318 9.5e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNHILNHP_02319 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MNHILNHP_02320 5.5e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MNHILNHP_02321 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MNHILNHP_02322 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MNHILNHP_02323 3e-139 IQ reductase
MNHILNHP_02324 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
MNHILNHP_02325 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MNHILNHP_02326 1.5e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MNHILNHP_02327 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MNHILNHP_02328 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MNHILNHP_02329 1.2e-202 camS S sex pheromone
MNHILNHP_02330 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MNHILNHP_02331 3.5e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MNHILNHP_02332 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MNHILNHP_02333 1e-187 yegS 2.7.1.107 G Lipid kinase
MNHILNHP_02334 3.1e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MNHILNHP_02335 2e-36
MNHILNHP_02336 1.1e-41 L Recombinase
MNHILNHP_02337 1.9e-71 K DNA binding
MNHILNHP_02339 2.1e-59 M Peptidase_C39 like family
MNHILNHP_02341 5.1e-75 csd1 3.5.1.28 G domain, Protein
MNHILNHP_02342 1.7e-105 L Helix-turn-helix domain
MNHILNHP_02343 6.1e-39 L Transposase
MNHILNHP_02344 1.7e-240 L Transposase
MNHILNHP_02345 7.9e-145 L PFAM Integrase catalytic region
MNHILNHP_02346 7.3e-86 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)