ORF_ID e_value Gene_name EC_number CAZy COGs Description
PFAPIKCO_00001 2.1e-204 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PFAPIKCO_00002 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PFAPIKCO_00003 2.2e-49 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PFAPIKCO_00004 5.3e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PFAPIKCO_00005 1.1e-199 nupG F Nucleoside
PFAPIKCO_00006 4.4e-122 MA20_14895 S Conserved hypothetical protein 698
PFAPIKCO_00007 1.7e-53 K LysR substrate binding domain
PFAPIKCO_00009 4.6e-66 yxkH G Polysaccharide deacetylase
PFAPIKCO_00010 4.3e-98 tnp2 L Transposase
PFAPIKCO_00011 9e-30 yqkB S Belongs to the HesB IscA family
PFAPIKCO_00014 8.6e-23
PFAPIKCO_00021 5.1e-08
PFAPIKCO_00027 1.4e-06
PFAPIKCO_00028 5.1e-263 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PFAPIKCO_00029 1.7e-54 rplI J Binds to the 23S rRNA
PFAPIKCO_00030 6.7e-206 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PFAPIKCO_00031 4e-64 C FMN binding
PFAPIKCO_00032 2.1e-230 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PFAPIKCO_00034 1.5e-156 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PFAPIKCO_00035 1.2e-59 ykhA 3.1.2.20 I Thioesterase superfamily
PFAPIKCO_00036 7.9e-12 S CAAX protease self-immunity
PFAPIKCO_00037 1.6e-81 S Belongs to the UPF0246 family
PFAPIKCO_00038 3.1e-30 L Helix-turn-helix domain
PFAPIKCO_00039 5.7e-89 L PFAM Integrase catalytic region
PFAPIKCO_00040 1.5e-71 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PFAPIKCO_00041 7.1e-129 yxjG 2.1.1.14 E Cobalamin-independent synthase, Catalytic domain
PFAPIKCO_00042 2.4e-73 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PFAPIKCO_00043 1.6e-196 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PFAPIKCO_00044 1.1e-160 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PFAPIKCO_00045 4e-42 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
PFAPIKCO_00046 4.9e-117 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
PFAPIKCO_00047 3.1e-202 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
PFAPIKCO_00048 1.1e-89 KT Putative sugar diacid recognition
PFAPIKCO_00049 1.7e-153 C Citrate transporter
PFAPIKCO_00050 7.2e-129 garR 1.1.1.60 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PFAPIKCO_00051 2.8e-217 gudD 4.2.1.40 M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
PFAPIKCO_00052 5.3e-103 4.3.3.7 EM Dihydrodipicolinate synthetase family
PFAPIKCO_00053 1.6e-109 tadA 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PFAPIKCO_00054 3.7e-98 yeaE S Aldo keto
PFAPIKCO_00055 6e-216 garD 4.2.1.42, 4.2.1.7 G D-galactarate dehydratase / Altronate hydrolase, C terminus
PFAPIKCO_00056 4.7e-34 4.2.1.40 M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
PFAPIKCO_00057 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_00058 5.4e-141 4.2.1.40 M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
PFAPIKCO_00060 3.3e-140 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PFAPIKCO_00061 1.1e-80 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PFAPIKCO_00062 3.3e-136 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
PFAPIKCO_00063 1.1e-148 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PFAPIKCO_00064 6.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PFAPIKCO_00065 1.9e-21 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PFAPIKCO_00066 6.5e-252 ctpA 3.6.3.54 P P-type ATPase
PFAPIKCO_00067 1.9e-65 pgm3 G phosphoglycerate mutase
PFAPIKCO_00068 1.1e-56 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
PFAPIKCO_00069 1.1e-85 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PFAPIKCO_00070 3.5e-218 yifK E Amino acid permease
PFAPIKCO_00071 1.3e-10 oppA E ABC transporter, substratebinding protein
PFAPIKCO_00072 2.2e-141 oppA E ABC transporter, substratebinding protein
PFAPIKCO_00073 7.9e-142 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFAPIKCO_00074 4.4e-170 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PFAPIKCO_00075 3.3e-181 oppD P Belongs to the ABC transporter superfamily
PFAPIKCO_00076 5.3e-154 oppF P Belongs to the ABC transporter superfamily
PFAPIKCO_00077 1.2e-15 psiE S Phosphate-starvation-inducible E
PFAPIKCO_00078 3.9e-206 mmuP E amino acid
PFAPIKCO_00079 1.8e-114 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PFAPIKCO_00080 5.3e-40 K LytTr DNA-binding domain
PFAPIKCO_00081 7.8e-18 S Protein of unknown function (DUF3021)
PFAPIKCO_00082 4.2e-151 yfeX P Peroxidase
PFAPIKCO_00083 6.1e-13 XK27_06935 K Transcriptional regulator C-terminal region
PFAPIKCO_00084 1.1e-215 L Probable transposase
PFAPIKCO_00086 2.4e-47 S Short repeat of unknown function (DUF308)
PFAPIKCO_00087 1.4e-52 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PFAPIKCO_00088 1.8e-162 oxlT P Major Facilitator Superfamily
PFAPIKCO_00089 4.5e-67 ybbL S ABC transporter
PFAPIKCO_00090 1.9e-101 ybbM S Uncharacterised protein family (UPF0014)
PFAPIKCO_00091 2.3e-41 ytcD K HxlR-like helix-turn-helix
PFAPIKCO_00092 9.5e-85 ytbE S reductase
PFAPIKCO_00093 2.6e-17 ytbE S reductase
PFAPIKCO_00094 7.8e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PFAPIKCO_00097 3.8e-09 3.1.3.48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PFAPIKCO_00101 1.1e-34 tetR K transcriptional regulator
PFAPIKCO_00103 1.2e-41 wecD K Acetyltransferase GNAT Family
PFAPIKCO_00104 2.5e-46 hmpT S ECF-type riboflavin transporter, S component
PFAPIKCO_00105 6.6e-71 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PFAPIKCO_00108 2.2e-111 dat 2.6.1.21 EH PFAM aminotransferase, class IV
PFAPIKCO_00109 5.8e-285 pepO 3.4.24.71 O Peptidase family M13
PFAPIKCO_00110 5.9e-44 thiT S Thiamine transporter protein (Thia_YuaJ)
PFAPIKCO_00111 3.3e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFAPIKCO_00112 4.3e-31 K Transcriptional regulator C-terminal region
PFAPIKCO_00113 1.6e-15
PFAPIKCO_00115 2.8e-131 S D5 N terminal like
PFAPIKCO_00116 3.3e-45 L DNA replication protein
PFAPIKCO_00122 5.2e-12 L Phage regulatory protein
PFAPIKCO_00123 1.4e-08 K Helix-turn-helix XRE-family like proteins
PFAPIKCO_00124 4.7e-14 K Transcriptional regulator, Cro CI family
PFAPIKCO_00125 1.2e-120 sip L Belongs to the 'phage' integrase family
PFAPIKCO_00126 1.6e-55 jag S R3H domain protein
PFAPIKCO_00127 4.5e-56 ohrR K helix_turn_helix multiple antibiotic resistance protein
PFAPIKCO_00128 1.1e-25 azlD S Branched-chain amino acid transport protein (AzlD)
PFAPIKCO_00129 1.5e-76 azlC E branched-chain amino acid
PFAPIKCO_00130 4.2e-59 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PFAPIKCO_00131 7.2e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PFAPIKCO_00132 1.8e-293 lai 4.2.1.53 S Myosin-crossreactive antigen
PFAPIKCO_00133 4.5e-33 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
PFAPIKCO_00134 6.3e-194 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PFAPIKCO_00135 4.1e-75 XK27_02070 S Nitroreductase family
PFAPIKCO_00136 1.7e-111 endA F DNA RNA non-specific endonuclease
PFAPIKCO_00137 1.6e-216 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_00139 2.5e-208 brnQ U Component of the transport system for branched-chain amino acids
PFAPIKCO_00140 1e-61 K Bacterial regulatory proteins, tetR family
PFAPIKCO_00141 4.2e-114 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PFAPIKCO_00142 2.9e-150 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PFAPIKCO_00143 5.6e-69 dhaL 2.7.1.121 S Dak2
PFAPIKCO_00144 3.1e-49 dhaM 2.7.1.121 S PTS system fructose IIA component
PFAPIKCO_00145 3.8e-104 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PFAPIKCO_00147 5.8e-177 yjcE P Sodium proton antiporter
PFAPIKCO_00148 2.3e-210 mtlR K Mga helix-turn-helix domain
PFAPIKCO_00149 8.6e-302 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PFAPIKCO_00150 4.7e-188 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PFAPIKCO_00151 5e-37 M Glycosyl hydrolases family 25
PFAPIKCO_00153 4.5e-102 tcyB E ABC transporter
PFAPIKCO_00154 4.1e-101 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PFAPIKCO_00155 2.8e-95 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PFAPIKCO_00156 5.5e-39 K Transcriptional regulator
PFAPIKCO_00157 1.7e-107 terC P Integral membrane protein TerC family
PFAPIKCO_00158 1.1e-261 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
PFAPIKCO_00159 2.8e-65 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFAPIKCO_00160 6.4e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
PFAPIKCO_00161 1.1e-41 gntR1 K Transcriptional regulator, GntR family
PFAPIKCO_00162 6.1e-96 V ABC transporter, ATP-binding protein
PFAPIKCO_00163 9.7e-08
PFAPIKCO_00164 1.1e-39 ybjQ S Belongs to the UPF0145 family
PFAPIKCO_00165 3.6e-158 manA 5.3.1.8 G mannose-6-phosphate isomerase
PFAPIKCO_00166 5.1e-97 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PFAPIKCO_00167 4e-157 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PFAPIKCO_00168 1.8e-141 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PFAPIKCO_00169 3.7e-34
PFAPIKCO_00170 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PFAPIKCO_00171 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PFAPIKCO_00172 5.2e-63 srtA 3.4.22.70 M sortase family
PFAPIKCO_00174 5.8e-71 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PFAPIKCO_00175 7.9e-62 yvdD 3.2.2.10 S Possible lysine decarboxylase
PFAPIKCO_00176 3.4e-185 L Probable transposase
PFAPIKCO_00177 0.0 pacL 3.6.3.8 P P-type ATPase
PFAPIKCO_00178 1.5e-108 3.1.4.46 C phosphodiesterase
PFAPIKCO_00179 1.6e-126 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PFAPIKCO_00180 6.2e-102 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PFAPIKCO_00181 1.7e-82 noc K Belongs to the ParB family
PFAPIKCO_00182 6.5e-118 soj D Sporulation initiation inhibitor
PFAPIKCO_00183 6.3e-109 spo0J K Belongs to the ParB family
PFAPIKCO_00184 1.8e-24 yyzM S Bacterial protein of unknown function (DUF951)
PFAPIKCO_00185 2.4e-190 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PFAPIKCO_00186 4.2e-53 XK27_01040 S Protein of unknown function (DUF1129)
PFAPIKCO_00187 1.5e-38
PFAPIKCO_00188 1.3e-103 psaA P Belongs to the bacterial solute-binding protein 9 family
PFAPIKCO_00189 1e-98 fhuC P ABC transporter
PFAPIKCO_00190 2.8e-95 znuB U ABC 3 transport family
PFAPIKCO_00191 1.5e-55 S ECF transporter, substrate-specific component
PFAPIKCO_00192 2.6e-101 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PFAPIKCO_00193 2.9e-89 S NADPH-dependent FMN reductase
PFAPIKCO_00194 1.2e-27 K helix_turn_helix, mercury resistance
PFAPIKCO_00195 2.6e-67 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PFAPIKCO_00197 5.8e-154 EGP Major facilitator Superfamily
PFAPIKCO_00198 1.3e-58 S Haloacid dehalogenase-like hydrolase
PFAPIKCO_00199 9.1e-89 yvyE 3.4.13.9 S YigZ family
PFAPIKCO_00200 1e-39 S CAAX protease self-immunity
PFAPIKCO_00201 5.8e-117 cps1D M Domain of unknown function (DUF4422)
PFAPIKCO_00202 1.3e-62 S Glycosyltransferase like family 2
PFAPIKCO_00203 6.6e-138 tetA EGP Major facilitator Superfamily
PFAPIKCO_00204 6.7e-32 yvdC S MazG nucleotide pyrophosphohydrolase domain
PFAPIKCO_00205 7.2e-214 yjeM E Amino Acid
PFAPIKCO_00206 1.3e-189 glnPH2 P ABC transporter permease
PFAPIKCO_00207 3.9e-112 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PFAPIKCO_00208 9.8e-45 E GDSL-like Lipase/Acylhydrolase
PFAPIKCO_00209 1.3e-133 coaA 2.7.1.33 F Pantothenic acid kinase
PFAPIKCO_00210 2.9e-274 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PFAPIKCO_00212 4.8e-173 rgpAc GT4 M Domain of unknown function (DUF1972)
PFAPIKCO_00213 5.2e-118 G Glycosyltransferase Family 4
PFAPIKCO_00214 1.1e-54 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
PFAPIKCO_00215 1.8e-128 sacB GT2,GT4 M Stealth protein CR3, conserved region 3
PFAPIKCO_00216 3.4e-62 M transferase activity, transferring glycosyl groups
PFAPIKCO_00217 1.6e-149 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
PFAPIKCO_00218 1.3e-17
PFAPIKCO_00219 2.1e-133 S Membrane protein involved in the export of O-antigen and teichoic acid
PFAPIKCO_00220 2.6e-67 S Glycosyltransferase like family 2
PFAPIKCO_00221 1.1e-38 licD2 M Psort location Cytoplasmic, score 8.87
PFAPIKCO_00222 7.1e-72 epsB M biosynthesis protein
PFAPIKCO_00223 1.2e-81 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PFAPIKCO_00224 1e-110 ywqE 3.1.3.48 GM PHP domain protein
PFAPIKCO_00225 4.5e-124 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PFAPIKCO_00226 9.1e-92 rfbP M Bacterial sugar transferase
PFAPIKCO_00227 4.2e-145 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PFAPIKCO_00228 4.2e-101 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PFAPIKCO_00229 3.6e-164 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PFAPIKCO_00230 4e-129 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PFAPIKCO_00231 3.3e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFAPIKCO_00233 1.7e-64 rny D Peptidase family M23
PFAPIKCO_00234 6.2e-43 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PFAPIKCO_00235 2.4e-92 M Core-2/I-Branching enzyme
PFAPIKCO_00236 2.4e-75 waaB GT4 M Glycosyl transferases group 1
PFAPIKCO_00237 2.6e-93 M transferase activity, transferring glycosyl groups
PFAPIKCO_00238 6.9e-58 cps3F
PFAPIKCO_00239 1.1e-73 M LicD family
PFAPIKCO_00240 1.9e-63 M Glycosyltransferase like family 2
PFAPIKCO_00241 2.5e-109 S Psort location CytoplasmicMembrane, score
PFAPIKCO_00242 4.7e-194 glf 5.4.99.9 M UDP-galactopyranose mutase
PFAPIKCO_00243 4e-153 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
PFAPIKCO_00245 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PFAPIKCO_00246 7.3e-161 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PFAPIKCO_00247 6.2e-96 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PFAPIKCO_00248 4.1e-67 XK27_09620 S NADPH-dependent FMN reductase
PFAPIKCO_00249 9.2e-157 XK27_09615 S reductase
PFAPIKCO_00250 1.2e-39 2.7.7.65 T phosphorelay sensor kinase activity
PFAPIKCO_00251 5.5e-146 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PFAPIKCO_00252 5.9e-53 cps3I G Acyltransferase family
PFAPIKCO_00253 3.6e-14
PFAPIKCO_00254 6.2e-161 XK27_08315 M Sulfatase
PFAPIKCO_00255 3.2e-177 thrC 4.2.3.1 E Threonine synthase
PFAPIKCO_00256 4.3e-82 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PFAPIKCO_00257 4.4e-36 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PFAPIKCO_00258 3.7e-166 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PFAPIKCO_00259 2.5e-89 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PFAPIKCO_00260 2.2e-177 licA 2.7.1.89 M Choline/ethanolamine kinase
PFAPIKCO_00261 1.9e-84 M Nucleotidyl transferase
PFAPIKCO_00262 1.1e-150 M BCCT, betaine/carnitine/choline family transporter
PFAPIKCO_00263 5.9e-56 S peptidoglycan catabolic process
PFAPIKCO_00264 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_00265 1.2e-188 XK27_08315 M Sulfatase
PFAPIKCO_00267 6.4e-168 mdtG EGP Major facilitator Superfamily
PFAPIKCO_00268 4.9e-251 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
PFAPIKCO_00269 3.7e-83 treR K UTRA
PFAPIKCO_00270 2.1e-258 treB G phosphotransferase system
PFAPIKCO_00271 3.5e-63 3.1.3.73 G phosphoglycerate mutase
PFAPIKCO_00272 2.4e-82 pncA Q isochorismatase
PFAPIKCO_00273 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PFAPIKCO_00274 2.2e-102 ydhQ K UbiC transcription regulator-associated domain protein
PFAPIKCO_00275 2.5e-170 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PFAPIKCO_00276 4e-33 K Transcriptional regulator, HxlR family
PFAPIKCO_00277 1.4e-21 C Luciferase-like monooxygenase
PFAPIKCO_00278 7.3e-94 C Luciferase-like monooxygenase
PFAPIKCO_00279 1.3e-24 1.5.1.38 S FMN reductase
PFAPIKCO_00280 4.3e-26 1.5.1.38 S NADPH-dependent FMN reductase
PFAPIKCO_00281 1.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PFAPIKCO_00282 3.9e-76 L haloacid dehalogenase-like hydrolase
PFAPIKCO_00283 3.1e-61 EG EamA-like transporter family
PFAPIKCO_00284 1.2e-117 K AI-2E family transporter
PFAPIKCO_00285 6.4e-173 malY 4.4.1.8 E Aminotransferase, class I
PFAPIKCO_00286 2.1e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PFAPIKCO_00288 4e-16
PFAPIKCO_00289 2.9e-105 V domain protein
PFAPIKCO_00290 8.3e-119 xth 3.1.11.2 L exodeoxyribonuclease III
PFAPIKCO_00291 2e-17
PFAPIKCO_00292 1.9e-104 azlC E AzlC protein
PFAPIKCO_00293 1.3e-38 azlD S branched-chain amino acid
PFAPIKCO_00294 3.6e-66 I alpha/beta hydrolase fold
PFAPIKCO_00295 1.1e-25
PFAPIKCO_00296 1.2e-58 3.6.1.27 I phosphatase
PFAPIKCO_00297 1.6e-22
PFAPIKCO_00298 4.5e-94 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PFAPIKCO_00299 6.3e-90 sirR K Helix-turn-helix diphteria tox regulatory element
PFAPIKCO_00300 3.1e-27 cspC K Cold shock protein
PFAPIKCO_00301 4.3e-82 thrE S Putative threonine/serine exporter
PFAPIKCO_00302 6.3e-49 S Threonine/Serine exporter, ThrE
PFAPIKCO_00303 1.2e-120 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PFAPIKCO_00304 4.2e-86 S Sucrose-6F-phosphate phosphohydrolase
PFAPIKCO_00305 1.9e-34 trxA O Belongs to the thioredoxin family
PFAPIKCO_00306 9.4e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PFAPIKCO_00307 3e-22 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PFAPIKCO_00308 1.5e-65 degV S Uncharacterised protein, DegV family COG1307
PFAPIKCO_00310 1.5e-54 queT S QueT transporter
PFAPIKCO_00311 2.5e-33 XK27_01315 S Protein of unknown function (DUF2829)
PFAPIKCO_00312 1.2e-100 IQ Enoyl-(Acyl carrier protein) reductase
PFAPIKCO_00313 1e-111 argE 3.5.1.18 E Peptidase dimerisation domain
PFAPIKCO_00314 1.9e-174 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PFAPIKCO_00315 1.6e-94 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PFAPIKCO_00316 4.5e-88 S Alpha beta hydrolase
PFAPIKCO_00317 2.7e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PFAPIKCO_00318 3.4e-138 V MatE
PFAPIKCO_00320 4.3e-98 tnp2 L Transposase
PFAPIKCO_00321 1.2e-25 D nuclear chromosome segregation
PFAPIKCO_00322 2e-114 V Abi-like protein
PFAPIKCO_00323 9.6e-98 tnp2 L Transposase
PFAPIKCO_00324 2.6e-155 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
PFAPIKCO_00325 3.1e-65 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PFAPIKCO_00326 2.5e-97 V ABC transporter
PFAPIKCO_00327 1.3e-131 bacI V MacB-like periplasmic core domain
PFAPIKCO_00328 4.3e-76 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PFAPIKCO_00329 2.2e-26
PFAPIKCO_00330 9.3e-181 yhdP S Transporter associated domain
PFAPIKCO_00331 7.5e-44 ptp2 3.1.3.48 T Tyrosine phosphatase family
PFAPIKCO_00332 1e-25 ptp2 3.1.3.48 T Tyrosine phosphatase family
PFAPIKCO_00333 0.0 L Helicase C-terminal domain protein
PFAPIKCO_00334 4.3e-251 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PFAPIKCO_00335 8.2e-97 tnp2 L Transposase
PFAPIKCO_00336 2.2e-212 yfnA E Amino Acid
PFAPIKCO_00337 9.8e-55 zur P Belongs to the Fur family
PFAPIKCO_00339 2.5e-97
PFAPIKCO_00341 1.3e-102 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PFAPIKCO_00342 1.1e-99 glnH ET ABC transporter
PFAPIKCO_00343 1.2e-85 gluC P ABC transporter permease
PFAPIKCO_00344 2.1e-77 glnP P ABC transporter permease
PFAPIKCO_00345 2.9e-182 steT E amino acid
PFAPIKCO_00346 8.4e-21 K Acetyltransferase (GNAT) domain
PFAPIKCO_00347 2.5e-146 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
PFAPIKCO_00348 4.5e-44 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PFAPIKCO_00349 2.9e-79 K rpiR family
PFAPIKCO_00350 6.2e-166 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PFAPIKCO_00351 3.7e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
PFAPIKCO_00352 4.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PFAPIKCO_00353 1e-100 rplD J Forms part of the polypeptide exit tunnel
PFAPIKCO_00354 8.5e-39 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PFAPIKCO_00355 1.4e-142 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PFAPIKCO_00356 1e-44 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PFAPIKCO_00357 1.5e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PFAPIKCO_00358 5.2e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PFAPIKCO_00359 2.3e-72 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PFAPIKCO_00360 9e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
PFAPIKCO_00361 8e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PFAPIKCO_00362 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PFAPIKCO_00363 7e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PFAPIKCO_00364 1.3e-91 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PFAPIKCO_00365 4.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PFAPIKCO_00366 2.5e-65 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PFAPIKCO_00367 3.2e-87 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PFAPIKCO_00368 9.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PFAPIKCO_00369 1.3e-82 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PFAPIKCO_00370 2.1e-22 rpmD J Ribosomal protein L30
PFAPIKCO_00371 1e-67 rplO J Binds to the 23S rRNA
PFAPIKCO_00372 7.4e-207 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PFAPIKCO_00373 4.4e-107 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PFAPIKCO_00374 4.8e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PFAPIKCO_00375 2.5e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PFAPIKCO_00376 4.4e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PFAPIKCO_00377 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PFAPIKCO_00378 1.3e-155 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFAPIKCO_00379 4.8e-53 rplQ J Ribosomal protein L17
PFAPIKCO_00380 5.7e-99 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFAPIKCO_00381 1.5e-110 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFAPIKCO_00382 2.2e-108 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PFAPIKCO_00383 9.4e-125 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PFAPIKCO_00384 5.5e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PFAPIKCO_00385 1.1e-60 rpsI J Belongs to the universal ribosomal protein uS9 family
PFAPIKCO_00386 1.7e-30
PFAPIKCO_00387 1.2e-245 yjbQ P TrkA C-terminal domain protein
PFAPIKCO_00388 0.0 helD 3.6.4.12 L DNA helicase
PFAPIKCO_00389 1e-67 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PFAPIKCO_00390 3.7e-85 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PFAPIKCO_00391 8.2e-111 hrtB V ABC transporter permease
PFAPIKCO_00392 1.5e-33 ygfC K Bacterial regulatory proteins, tetR family
PFAPIKCO_00393 1.1e-85 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PFAPIKCO_00394 5.6e-277 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PFAPIKCO_00395 7.6e-39 M LysM domain protein
PFAPIKCO_00396 1.4e-116 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PFAPIKCO_00397 8.8e-97 sbcC L Putative exonuclease SbcCD, C subunit
PFAPIKCO_00398 2.9e-57 S LexA-binding, inner membrane-associated putative hydrolase
PFAPIKCO_00399 7.2e-53 perR P Belongs to the Fur family
PFAPIKCO_00400 1.1e-207 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PFAPIKCO_00401 8.1e-142 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PFAPIKCO_00402 5.5e-86 S (CBS) domain
PFAPIKCO_00403 4.8e-158 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PFAPIKCO_00404 3.2e-74 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PFAPIKCO_00405 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PFAPIKCO_00406 7.3e-140 yabM S Polysaccharide biosynthesis protein
PFAPIKCO_00407 3.6e-31 yabO J S4 domain protein
PFAPIKCO_00408 2.3e-18 divIC D Septum formation initiator
PFAPIKCO_00409 1.1e-40 yabR J RNA binding
PFAPIKCO_00410 7.2e-96 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PFAPIKCO_00411 1.9e-76 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PFAPIKCO_00412 3e-282 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PFAPIKCO_00413 1.6e-131 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PFAPIKCO_00414 1.6e-169 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PFAPIKCO_00415 2.6e-259 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PFAPIKCO_00416 1.1e-203 L Transposase
PFAPIKCO_00417 2.1e-112 UW LPXTG-motif cell wall anchor domain protein
PFAPIKCO_00418 2.8e-97 tnp2 L Transposase
PFAPIKCO_00419 4.2e-70 L Transposase
PFAPIKCO_00420 1.6e-79 L transposase and inactivated derivatives, IS30 family
PFAPIKCO_00421 5.3e-35 tra L Transposase and inactivated derivatives, IS30 family
PFAPIKCO_00422 1.1e-16 K Cro/C1-type HTH DNA-binding domain
PFAPIKCO_00424 3.8e-39 ebh D nuclear chromosome segregation
PFAPIKCO_00425 1.3e-135 L Transposase
PFAPIKCO_00426 1.9e-122 L Transposase
PFAPIKCO_00429 3.7e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PFAPIKCO_00430 4.9e-10 L Resolvase, N terminal domain
PFAPIKCO_00432 1.7e-78 L Resolvase, N terminal domain
PFAPIKCO_00433 9.6e-13 S Helix-turn-helix domain
PFAPIKCO_00434 1.5e-94
PFAPIKCO_00435 4.5e-112
PFAPIKCO_00438 3.1e-19 S Excisionase from transposon Tn916
PFAPIKCO_00439 4.5e-169 L Belongs to the 'phage' integrase family
PFAPIKCO_00440 8.6e-23
PFAPIKCO_00444 2.1e-144 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PFAPIKCO_00445 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PFAPIKCO_00446 4.3e-278 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PFAPIKCO_00447 7.1e-161 camS S sex pheromone
PFAPIKCO_00448 7.6e-38 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PFAPIKCO_00449 1.1e-233 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PFAPIKCO_00450 1.6e-255 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PFAPIKCO_00451 9.8e-146 yegS 2.7.1.107 G Lipid kinase
PFAPIKCO_00452 1.8e-211 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PFAPIKCO_00453 1.2e-36 sugE U Multidrug resistance protein
PFAPIKCO_00454 1.5e-196 L Recombinase
PFAPIKCO_00455 7.1e-15 S Recombinase
PFAPIKCO_00456 1.9e-116 L Recombinase zinc beta ribbon domain
PFAPIKCO_00458 2.9e-51 S Bacteriophage holin family
PFAPIKCO_00459 5.6e-46 S Phage head-tail joining protein
PFAPIKCO_00460 5.4e-30 S Phage gp6-like head-tail connector protein
PFAPIKCO_00461 2.5e-169 S Phage capsid family
PFAPIKCO_00462 1e-71 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
PFAPIKCO_00463 2.6e-217 S Phage portal protein
PFAPIKCO_00464 2.8e-11 K Antidote-toxin recognition MazE, bacterial antitoxin
PFAPIKCO_00466 1.5e-289 S overlaps another CDS with the same product name
PFAPIKCO_00467 1.1e-24 S Domain of unknown function (DUF5049)
PFAPIKCO_00468 1.5e-51 S Psort location Cytoplasmic, score
PFAPIKCO_00469 7.1e-199 2.1.1.72 KL DNA methylase
PFAPIKCO_00470 5.7e-92
PFAPIKCO_00471 4.6e-56 V HNH nucleases
PFAPIKCO_00472 2.1e-50
PFAPIKCO_00473 1.8e-198 L SNF2 family N-terminal domain
PFAPIKCO_00474 2.8e-32 S VRR_NUC
PFAPIKCO_00475 0.0 S Phage plasmid primase, P4
PFAPIKCO_00476 1.1e-39 S Psort location Cytoplasmic, score
PFAPIKCO_00477 1.2e-301 polA_2 2.7.7.7 L DNA polymerase
PFAPIKCO_00478 5e-88 S Protein of unknown function (DUF2815)
PFAPIKCO_00479 1.9e-174 L Protein of unknown function (DUF2800)
PFAPIKCO_00481 5.4e-08
PFAPIKCO_00483 4.1e-19 S Domain of unknown function (DUF1837)
PFAPIKCO_00484 5.6e-129 L Helicase conserved C-terminal domain
PFAPIKCO_00485 3.4e-19 K Cro/C1-type HTH DNA-binding domain
PFAPIKCO_00486 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PFAPIKCO_00487 2.5e-207 hsdM 2.1.1.72 V cog cog0286
PFAPIKCO_00488 3e-98 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PFAPIKCO_00489 1.8e-125 S Bacteriophage abortive infection AbiH
PFAPIKCO_00491 1e-119 L Mrr N-terminal domain
PFAPIKCO_00492 1.3e-17
PFAPIKCO_00493 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_00495 2.9e-29 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PFAPIKCO_00496 6.7e-72 ywlG S Belongs to the UPF0340 family
PFAPIKCO_00497 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PFAPIKCO_00498 2.8e-96 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PFAPIKCO_00499 8.8e-58 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PFAPIKCO_00500 9.6e-98 tnp2 L Transposase
PFAPIKCO_00501 3.1e-176 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
PFAPIKCO_00502 5.7e-14 ybaN S Protein of unknown function (DUF454)
PFAPIKCO_00503 1.1e-237 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PFAPIKCO_00504 2.7e-199 frdC 1.3.5.4 C FAD binding domain
PFAPIKCO_00505 5.3e-206 yflS P Sodium:sulfate symporter transmembrane region
PFAPIKCO_00506 9.3e-37 yncA 2.3.1.79 S Maltose acetyltransferase
PFAPIKCO_00507 1.4e-162 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PFAPIKCO_00508 8.4e-60 dedA 3.1.3.1 S SNARE associated Golgi protein
PFAPIKCO_00509 1.9e-95 ypuA S Protein of unknown function (DUF1002)
PFAPIKCO_00510 3.9e-95 3.2.1.18 GH33 M Rib/alpha-like repeat
PFAPIKCO_00511 4.7e-31 3.2.1.18 GH33 M Rib/alpha-like repeat
PFAPIKCO_00512 5.3e-116 3.2.1.18 GH33 M Rib/alpha-like repeat
PFAPIKCO_00513 1.2e-44 K Copper transport repressor CopY TcrY
PFAPIKCO_00514 6.1e-60 T Belongs to the universal stress protein A family
PFAPIKCO_00515 2.6e-41 K Bacterial regulatory proteins, tetR family
PFAPIKCO_00516 1.1e-56 K transcriptional
PFAPIKCO_00517 1.9e-68 mleR K LysR family
PFAPIKCO_00518 1.7e-248 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PFAPIKCO_00519 5.7e-127 mleP S Sodium Bile acid symporter family
PFAPIKCO_00520 2.5e-64 S ECF transporter, substrate-specific component
PFAPIKCO_00521 6.3e-61 acmC 3.2.1.96 NU mannosyl-glycoprotein
PFAPIKCO_00522 3.3e-74 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PFAPIKCO_00523 9.7e-194 pbuX F xanthine permease
PFAPIKCO_00524 3.1e-34 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PFAPIKCO_00525 1.3e-258 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PFAPIKCO_00526 2.5e-94 yjbM 2.7.6.5 S RelA SpoT domain protein
PFAPIKCO_00527 7.6e-117 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PFAPIKCO_00528 6.9e-95 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PFAPIKCO_00529 1.9e-176 mgtE P Acts as a magnesium transporter
PFAPIKCO_00531 1.7e-40
PFAPIKCO_00532 3.7e-34 K GNAT family
PFAPIKCO_00533 2.2e-209 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PFAPIKCO_00534 5.5e-221 gdhA 1.4.1.4 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
PFAPIKCO_00535 3.8e-42 O ADP-ribosylglycohydrolase
PFAPIKCO_00536 2.1e-220 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PFAPIKCO_00537 2.1e-266 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PFAPIKCO_00538 1.2e-163 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PFAPIKCO_00539 4e-119 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
PFAPIKCO_00540 9.4e-195 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
PFAPIKCO_00541 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PFAPIKCO_00542 1.2e-175 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
PFAPIKCO_00543 3.4e-24 S Domain of unknown function (DUF4828)
PFAPIKCO_00544 7e-128 mocA S Oxidoreductase
PFAPIKCO_00545 2e-159 yfmL L DEAD DEAH box helicase
PFAPIKCO_00546 2e-20 S Domain of unknown function (DUF3284)
PFAPIKCO_00548 1e-279 kup P Transport of potassium into the cell
PFAPIKCO_00549 9.4e-101 malR K Transcriptional regulator, LacI family
PFAPIKCO_00550 4.3e-213 malT G Transporter, major facilitator family protein
PFAPIKCO_00551 7.7e-79 galM 5.1.3.3 G Aldose 1-epimerase
PFAPIKCO_00552 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PFAPIKCO_00553 2.4e-84 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PFAPIKCO_00554 1.9e-98 tnp2 L Transposase
PFAPIKCO_00555 9.1e-263 E Amino acid permease
PFAPIKCO_00556 2.3e-181 pepS E Thermophilic metalloprotease (M29)
PFAPIKCO_00557 4.6e-168 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PFAPIKCO_00558 1.8e-70 K Sugar-specific transcriptional regulator TrmB
PFAPIKCO_00559 2.4e-55 S Sulfite exporter TauE/SafE
PFAPIKCO_00560 1.8e-183 L Probable transposase
PFAPIKCO_00561 3.4e-30 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
PFAPIKCO_00562 1.2e-78 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
PFAPIKCO_00563 0.0 S Bacterial membrane protein YfhO
PFAPIKCO_00564 5.1e-53 gtcA S Teichoic acid glycosylation protein
PFAPIKCO_00565 5.1e-54 fld C Flavodoxin
PFAPIKCO_00566 1.2e-143 map 3.4.11.18 E Methionine Aminopeptidase
PFAPIKCO_00567 1.2e-152 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PFAPIKCO_00568 4.7e-12 mltD CBM50 M Lysin motif
PFAPIKCO_00569 3.8e-93 yihY S Belongs to the UPF0761 family
PFAPIKCO_00570 8.6e-23
PFAPIKCO_00572 1.6e-197 dtpT U amino acid peptide transporter
PFAPIKCO_00573 1.1e-07
PFAPIKCO_00575 4.6e-90 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PFAPIKCO_00576 4.9e-96 gntR1 K UbiC transcription regulator-associated domain protein
PFAPIKCO_00577 2.1e-89 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PFAPIKCO_00578 2.5e-243 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PFAPIKCO_00579 1.4e-129 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PFAPIKCO_00580 2.8e-251 yhgF K Tex-like protein N-terminal domain protein
PFAPIKCO_00581 3.6e-44 ydcK S Belongs to the SprT family
PFAPIKCO_00583 4.6e-116 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PFAPIKCO_00584 4.5e-129 mleP2 S Sodium Bile acid symporter family
PFAPIKCO_00585 2.9e-85 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PFAPIKCO_00586 1e-33 S Enterocin A Immunity
PFAPIKCO_00587 5.8e-223 pepC 3.4.22.40 E Peptidase C1-like family
PFAPIKCO_00588 4.3e-19 HA62_12640 S GCN5-related N-acetyl-transferase
PFAPIKCO_00589 6.9e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PFAPIKCO_00590 1.6e-223 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PFAPIKCO_00591 1.2e-152 yacL S domain protein
PFAPIKCO_00592 4.9e-247 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PFAPIKCO_00593 3.6e-207 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PFAPIKCO_00594 6.4e-56 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PFAPIKCO_00595 1.6e-108 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PFAPIKCO_00596 7e-71 yacP S YacP-like NYN domain
PFAPIKCO_00597 2.1e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PFAPIKCO_00598 2.6e-11 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PFAPIKCO_00599 7.7e-84 nusG K Participates in transcription elongation, termination and antitermination
PFAPIKCO_00600 5e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PFAPIKCO_00601 1.6e-115 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PFAPIKCO_00602 7.6e-75 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PFAPIKCO_00603 2.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PFAPIKCO_00604 1.4e-54
PFAPIKCO_00605 2.1e-301 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PFAPIKCO_00606 1e-160 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PFAPIKCO_00607 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PFAPIKCO_00608 4.8e-45 nrdI F NrdI Flavodoxin like
PFAPIKCO_00609 2.7e-27 nrdH O Glutaredoxin
PFAPIKCO_00610 6.4e-76 rsmC 2.1.1.172 J Methyltransferase
PFAPIKCO_00611 3.3e-62 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PFAPIKCO_00612 5.1e-211 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PFAPIKCO_00613 7e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PFAPIKCO_00614 5.2e-76 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PFAPIKCO_00615 1.3e-28 yaaL S Protein of unknown function (DUF2508)
PFAPIKCO_00616 1.8e-65 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PFAPIKCO_00617 1e-83 holB 2.7.7.7 L DNA polymerase III
PFAPIKCO_00618 1.4e-40 yabA L Involved in initiation control of chromosome replication
PFAPIKCO_00619 1.9e-92 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PFAPIKCO_00620 5.5e-82 fat 3.1.2.21 I Acyl-ACP thioesterase
PFAPIKCO_00621 2.7e-140 ansA 3.5.1.1 EJ Asparaginase
PFAPIKCO_00622 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_00623 6.6e-31 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PFAPIKCO_00624 2.2e-30 yeaZ 2.3.1.234 O PFAM Peptidase M22, glycoprotease
PFAPIKCO_00625 4.3e-28 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PFAPIKCO_00626 2.9e-161 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PFAPIKCO_00627 1.2e-253 uup S ABC transporter, ATP-binding protein
PFAPIKCO_00628 2.8e-98 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PFAPIKCO_00629 2.4e-33 S CAAX protease self-immunity
PFAPIKCO_00630 2.4e-33 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PFAPIKCO_00631 1.8e-271 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PFAPIKCO_00632 1.9e-269 aha1 P COG COG0474 Cation transport ATPase
PFAPIKCO_00633 4.1e-296 ydaO E amino acid
PFAPIKCO_00634 1.6e-157 tagO 2.7.8.33, 2.7.8.35 M transferase
PFAPIKCO_00635 5.4e-128 comFA L Helicase C-terminal domain protein
PFAPIKCO_00636 1e-45 comFC S Competence protein
PFAPIKCO_00637 6e-81 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PFAPIKCO_00638 3.1e-95 yeaN P Major Facilitator Superfamily
PFAPIKCO_00639 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PFAPIKCO_00640 4.9e-164 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PFAPIKCO_00641 1e-66 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
PFAPIKCO_00642 1.7e-85 K response regulator
PFAPIKCO_00643 1e-84 phoR 2.7.13.3 T Histidine kinase
PFAPIKCO_00644 4.1e-08 KT PspC domain protein
PFAPIKCO_00645 1.6e-26 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PFAPIKCO_00646 7.4e-132 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PFAPIKCO_00647 1.1e-112 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PFAPIKCO_00648 6.1e-273 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PFAPIKCO_00649 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PFAPIKCO_00650 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PFAPIKCO_00651 1.1e-83 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PFAPIKCO_00652 2.9e-79 ylbE GM NAD dependent epimerase dehydratase family protein
PFAPIKCO_00653 7.5e-126 rapZ S Displays ATPase and GTPase activities
PFAPIKCO_00654 8.2e-153 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PFAPIKCO_00655 1.8e-149 whiA K May be required for sporulation
PFAPIKCO_00656 1.1e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PFAPIKCO_00657 3.3e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFAPIKCO_00659 6.4e-137 cggR K Putative sugar-binding domain
PFAPIKCO_00660 6.1e-180 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PFAPIKCO_00661 1.3e-208 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PFAPIKCO_00662 2.3e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PFAPIKCO_00663 9.5e-234 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PFAPIKCO_00664 5e-132 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PFAPIKCO_00665 1.9e-103 K response regulator
PFAPIKCO_00666 4.1e-169 T PhoQ Sensor
PFAPIKCO_00667 8.7e-146 lmrP E Major Facilitator Superfamily
PFAPIKCO_00668 6e-179 clcA P chloride
PFAPIKCO_00669 2.8e-19 secG U Preprotein translocase
PFAPIKCO_00670 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PFAPIKCO_00671 6.9e-70 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PFAPIKCO_00672 3.1e-42 yxjI
PFAPIKCO_00673 1.8e-116 ycsE S Sucrose-6F-phosphate phosphohydrolase
PFAPIKCO_00674 5.2e-106 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PFAPIKCO_00675 1.3e-142 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PFAPIKCO_00676 1.6e-55 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PFAPIKCO_00677 3e-69 dnaQ 2.7.7.7 L DNA polymerase III
PFAPIKCO_00678 1.2e-115 murB 1.3.1.98 M Cell wall formation
PFAPIKCO_00679 2.4e-71 S Protein of unknown function (DUF1361)
PFAPIKCO_00680 8.5e-127 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PFAPIKCO_00681 5.3e-68 ybbR S YbbR-like protein
PFAPIKCO_00682 2.6e-226 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PFAPIKCO_00683 7.5e-29 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PFAPIKCO_00684 5.3e-131 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PFAPIKCO_00685 3.2e-21 cutC P Participates in the control of copper homeostasis
PFAPIKCO_00686 4e-197 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PFAPIKCO_00687 5.9e-164 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PFAPIKCO_00688 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_00689 1.9e-60 ybaK J Aminoacyl-tRNA editing domain
PFAPIKCO_00690 3.7e-98 rrmA 2.1.1.187 H Methyltransferase
PFAPIKCO_00691 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_00692 4.4e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PFAPIKCO_00693 2.7e-284 ftsK D Belongs to the FtsK SpoIIIE SftA family
PFAPIKCO_00694 5.3e-109 ymfF S Peptidase M16 inactive domain protein
PFAPIKCO_00695 2.4e-149 ymfH S Peptidase M16
PFAPIKCO_00696 2.4e-90 IQ Enoyl-(Acyl carrier protein) reductase
PFAPIKCO_00697 2.9e-64 ymfM S Helix-turn-helix domain
PFAPIKCO_00698 1.4e-83 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PFAPIKCO_00699 3.7e-97 tnp2 L Transposase
PFAPIKCO_00700 2.3e-159 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PFAPIKCO_00701 2.6e-182 rny S Endoribonuclease that initiates mRNA decay
PFAPIKCO_00702 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PFAPIKCO_00703 2.1e-224 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PFAPIKCO_00704 4.3e-72 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PFAPIKCO_00705 6.3e-153 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PFAPIKCO_00706 2.1e-183 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PFAPIKCO_00707 2.9e-207 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PFAPIKCO_00708 1.8e-12 yajC U Preprotein translocase
PFAPIKCO_00710 4.3e-61 uspA T universal stress protein
PFAPIKCO_00712 2e-208 yfnA E Amino Acid
PFAPIKCO_00713 6.9e-117 lutA C Cysteine-rich domain
PFAPIKCO_00714 1.6e-245 lutB C 4Fe-4S dicluster domain
PFAPIKCO_00715 2e-71 yrjD S LUD domain
PFAPIKCO_00716 2.7e-147 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PFAPIKCO_00717 7.5e-13
PFAPIKCO_00718 9.4e-122 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PFAPIKCO_00719 1e-187 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PFAPIKCO_00720 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PFAPIKCO_00721 2.1e-36 yrzL S Belongs to the UPF0297 family
PFAPIKCO_00722 1e-59 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PFAPIKCO_00723 1.9e-33 yrzB S Belongs to the UPF0473 family
PFAPIKCO_00724 2.4e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PFAPIKCO_00725 7.5e-15 cvpA S Colicin V production protein
PFAPIKCO_00726 5.5e-309 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PFAPIKCO_00727 1.3e-40 trxA O Belongs to the thioredoxin family
PFAPIKCO_00728 1.1e-60 yslB S Protein of unknown function (DUF2507)
PFAPIKCO_00729 5e-73 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PFAPIKCO_00730 1.1e-41 S Phosphoesterase
PFAPIKCO_00733 7.5e-140 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFAPIKCO_00734 9.6e-306 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PFAPIKCO_00735 8.2e-214 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PFAPIKCO_00736 5.6e-200 oatA I Acyltransferase
PFAPIKCO_00737 3.1e-16
PFAPIKCO_00739 8.9e-141 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PFAPIKCO_00740 5.8e-101 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
PFAPIKCO_00741 4.7e-220 recJ L Single-stranded-DNA-specific exonuclease RecJ
PFAPIKCO_00742 1.3e-80 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PFAPIKCO_00743 1.2e-296 S membrane
PFAPIKCO_00744 2.3e-279 pbp2b 3.4.16.4 M Penicillin-binding Protein
PFAPIKCO_00745 5.2e-27 S Protein of unknown function (DUF3290)
PFAPIKCO_00746 1.7e-74 yviA S Protein of unknown function (DUF421)
PFAPIKCO_00750 7.7e-125 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PFAPIKCO_00751 1.7e-199 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PFAPIKCO_00752 3.7e-54 tag 3.2.2.20 L glycosylase
PFAPIKCO_00753 3.2e-73 usp6 T universal stress protein
PFAPIKCO_00755 5.8e-188 rarA L recombination factor protein RarA
PFAPIKCO_00756 1.5e-24 yueI S Protein of unknown function (DUF1694)
PFAPIKCO_00757 7.5e-101 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PFAPIKCO_00758 4.2e-56 ytsP 1.8.4.14 T GAF domain-containing protein
PFAPIKCO_00759 1.1e-173 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PFAPIKCO_00760 1.3e-162 iscS2 2.8.1.7 E Aminotransferase class V
PFAPIKCO_00761 1.5e-196 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PFAPIKCO_00762 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PFAPIKCO_00763 8.1e-137 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PFAPIKCO_00764 6.9e-79 radC L DNA repair protein
PFAPIKCO_00765 4.5e-21 K Cold shock
PFAPIKCO_00766 3.6e-156 mreB D cell shape determining protein MreB
PFAPIKCO_00767 2.1e-88 mreC M Involved in formation and maintenance of cell shape
PFAPIKCO_00768 1.5e-54 mreD M rod shape-determining protein MreD
PFAPIKCO_00769 4.1e-76 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PFAPIKCO_00770 1.8e-126 minD D Belongs to the ParA family
PFAPIKCO_00771 1.9e-94 glnP P ABC transporter permease
PFAPIKCO_00772 1.8e-89 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PFAPIKCO_00773 1.1e-108 aatB ET ABC transporter substrate-binding protein
PFAPIKCO_00774 9.8e-100 D Alpha beta
PFAPIKCO_00775 1.2e-155 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
PFAPIKCO_00776 2.2e-07 S Protein of unknown function (DUF3397)
PFAPIKCO_00777 5.2e-64 mraZ K Belongs to the MraZ family
PFAPIKCO_00778 6.7e-141 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PFAPIKCO_00779 2.5e-11 ftsL D cell division protein FtsL
PFAPIKCO_00780 2.4e-282 ftsI 3.4.16.4 M Penicillin-binding Protein
PFAPIKCO_00781 8.7e-136 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PFAPIKCO_00782 2.2e-185 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PFAPIKCO_00783 1.5e-152 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PFAPIKCO_00784 6.3e-61 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PFAPIKCO_00785 5.2e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PFAPIKCO_00786 3.4e-180 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PFAPIKCO_00787 3.8e-33 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PFAPIKCO_00788 3e-19 yggT S YGGT family
PFAPIKCO_00789 3.5e-82 ylmH S S4 domain protein
PFAPIKCO_00790 1.9e-61 divIVA D DivIVA domain protein
PFAPIKCO_00791 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PFAPIKCO_00792 2.5e-102 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFAPIKCO_00793 4.4e-74 draG O ADP-ribosylglycohydrolase
PFAPIKCO_00795 6.7e-86 2.7.7.12 C Domain of unknown function (DUF4931)
PFAPIKCO_00796 1.1e-92 T Calcineurin-like phosphoesterase superfamily domain
PFAPIKCO_00797 3.5e-48 lytE M LysM domain protein
PFAPIKCO_00798 5e-19 glpE P Rhodanese Homology Domain
PFAPIKCO_00799 2.4e-27 xlyB 3.5.1.28 CBM50 M LysM domain
PFAPIKCO_00800 6.9e-160 asnA 6.3.1.1 F aspartate--ammonia ligase
PFAPIKCO_00801 7.9e-194 cydA 1.10.3.14 C ubiquinol oxidase
PFAPIKCO_00802 2.5e-141 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PFAPIKCO_00803 7.1e-205 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PFAPIKCO_00804 6.1e-220 cydD CO ABC transporter transmembrane region
PFAPIKCO_00805 1.1e-96 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PFAPIKCO_00806 3.3e-105 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PFAPIKCO_00807 6.6e-157 ndh 1.6.99.3 C NADH dehydrogenase
PFAPIKCO_00808 1.6e-145 pbuO_1 S Permease family
PFAPIKCO_00809 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_00810 2.1e-43 2.7.7.65 T GGDEF domain
PFAPIKCO_00811 6.2e-44 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
PFAPIKCO_00812 5.7e-89 L PFAM Integrase catalytic region
PFAPIKCO_00813 3.5e-30 L Helix-turn-helix domain
PFAPIKCO_00814 4.9e-67 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
PFAPIKCO_00815 2.1e-181
PFAPIKCO_00816 5.8e-206 S Protein conserved in bacteria
PFAPIKCO_00817 1.2e-201 ydaM M Glycosyl transferase family group 2
PFAPIKCO_00818 0.0 ydaN S Bacterial cellulose synthase subunit
PFAPIKCO_00819 1.9e-113 2.7.7.65 T diguanylate cyclase activity
PFAPIKCO_00820 5e-38 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
PFAPIKCO_00821 3.9e-59 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
PFAPIKCO_00822 0.0 rafA 3.2.1.22 G alpha-galactosidase
PFAPIKCO_00823 1.5e-53 S Membrane
PFAPIKCO_00824 9.1e-65 K helix_turn_helix, arabinose operon control protein
PFAPIKCO_00825 5.6e-44
PFAPIKCO_00826 4.5e-205 pipD E Dipeptidase
PFAPIKCO_00827 1.1e-23 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PFAPIKCO_00828 1.5e-191 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PFAPIKCO_00829 1.5e-60 speG J Acetyltransferase (GNAT) domain
PFAPIKCO_00830 1e-113 yitU 3.1.3.104 S hydrolase
PFAPIKCO_00831 1.1e-83 yjfP S COG1073 Hydrolases of the alpha beta superfamily
PFAPIKCO_00832 8.1e-81
PFAPIKCO_00833 3.8e-177 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PFAPIKCO_00834 2.3e-42 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PFAPIKCO_00835 2.9e-11 M Glycosyl transferases group 1
PFAPIKCO_00836 4.5e-07
PFAPIKCO_00837 5.2e-84 qorB 1.6.5.2 GM NmrA-like family
PFAPIKCO_00838 3.6e-39 K Transcriptional regulator
PFAPIKCO_00839 1.9e-31 S CHY zinc finger
PFAPIKCO_00840 4.3e-85 1.1.1.1 C Zinc-binding dehydrogenase
PFAPIKCO_00842 3.4e-41 S Protein of unknown function (DUF1211)
PFAPIKCO_00843 5.2e-25 ybl78 L Conserved phage C-terminus (Phg_2220_C)
PFAPIKCO_00845 5.6e-41 wecD M Acetyltransferase (GNAT) family
PFAPIKCO_00846 2.9e-75 cps2D 5.1.3.2 M RmlD substrate binding domain
PFAPIKCO_00847 1.1e-64 H Methyltransferase domain
PFAPIKCO_00849 1.3e-16 K DNA-templated transcription, initiation
PFAPIKCO_00851 2.2e-08 S Protein of unknown function (DUF2922)
PFAPIKCO_00854 8.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
PFAPIKCO_00855 1e-27 ysxB J Cysteine protease Prp
PFAPIKCO_00856 1.6e-42 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PFAPIKCO_00857 4.7e-09 M LysM domain
PFAPIKCO_00859 1.2e-26 S Cysteine-rich CPCC
PFAPIKCO_00861 9.7e-73
PFAPIKCO_00862 2.9e-99 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PFAPIKCO_00863 2.7e-179 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PFAPIKCO_00864 6e-123 xerC D Belongs to the 'phage' integrase family. XerC subfamily
PFAPIKCO_00865 7e-79 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PFAPIKCO_00866 7.8e-218 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PFAPIKCO_00867 4.6e-37 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PFAPIKCO_00868 1.6e-58 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PFAPIKCO_00869 1.1e-56 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PFAPIKCO_00870 3.8e-99 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PFAPIKCO_00871 2e-58 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PFAPIKCO_00872 4.1e-51 yeaL S Protein of unknown function (DUF441)
PFAPIKCO_00873 1.1e-124 cvfB S S1 domain
PFAPIKCO_00874 4.3e-113 xerD D recombinase XerD
PFAPIKCO_00875 4.9e-265 L PFAM Integrase catalytic region
PFAPIKCO_00876 1.1e-293 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PFAPIKCO_00877 1.8e-76 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PFAPIKCO_00878 1.4e-187 nhaC C Na H antiporter NhaC
PFAPIKCO_00879 5.1e-64 ypsA S Belongs to the UPF0398 family
PFAPIKCO_00880 1.9e-197 ade 3.5.4.2 F Adenine deaminase C-terminal domain
PFAPIKCO_00882 2.2e-73 2.3.1.178 M GNAT acetyltransferase
PFAPIKCO_00883 1.8e-68 maa 2.3.1.79 S Maltose acetyltransferase
PFAPIKCO_00884 5.7e-57 3.6.1.27 I Acid phosphatase homologues
PFAPIKCO_00885 3e-81 XK27_07525 3.6.1.55 F Hydrolase, nudix family
PFAPIKCO_00887 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PFAPIKCO_00888 8.8e-202 hsdM 2.1.1.72 V type I restriction-modification system
PFAPIKCO_00889 2.4e-77 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
PFAPIKCO_00890 2.8e-131 L Belongs to the 'phage' integrase family
PFAPIKCO_00891 1.1e-62 3.1.21.3 V Type I restriction modification DNA specificity domain
PFAPIKCO_00892 8.2e-23 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PFAPIKCO_00893 2.4e-34 3.1.21.3 V type I restriction modification DNA specificity domain protein
PFAPIKCO_00894 2.2e-35 3.1.21.3 V Type I restriction modification DNA specificity domain
PFAPIKCO_00895 7.4e-69 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PFAPIKCO_00896 1.7e-24 E Alpha/beta hydrolase of unknown function (DUF915)
PFAPIKCO_00897 7.7e-71 pepE 3.4.13.21 E Alpha/beta hydrolase of unknown function (DUF915)
PFAPIKCO_00898 3.7e-168 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PFAPIKCO_00899 7.1e-08 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PFAPIKCO_00900 1.2e-242 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PFAPIKCO_00901 6.1e-204 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PFAPIKCO_00902 1.3e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PFAPIKCO_00903 1.1e-220 mntH P H( )-stimulated, divalent metal cation uptake system
PFAPIKCO_00904 1.4e-59 ypbB 5.1.3.1 S Helix-turn-helix domain
PFAPIKCO_00905 2.9e-127 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PFAPIKCO_00906 7.7e-12 M Lysin motif
PFAPIKCO_00907 1.3e-85 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PFAPIKCO_00908 9.8e-83 lytH 3.5.1.28 M Ami_3
PFAPIKCO_00909 1.2e-153 phoH T phosphate starvation-inducible protein PhoH
PFAPIKCO_00910 1.5e-67 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PFAPIKCO_00911 4.7e-30 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PFAPIKCO_00912 3.5e-155 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PFAPIKCO_00913 1.5e-90 recO L Involved in DNA repair and RecF pathway recombination
PFAPIKCO_00914 2.6e-07 dltX S D-Ala-teichoic acid biosynthesis protein
PFAPIKCO_00915 9e-220 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFAPIKCO_00916 5.9e-174 dltB M MBOAT, membrane-bound O-acyltransferase family
PFAPIKCO_00917 5.4e-28 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PFAPIKCO_00918 1.5e-151 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PFAPIKCO_00919 9.1e-58 arsC 1.20.4.1 T Low molecular weight phosphatase family
PFAPIKCO_00920 2.7e-171 rpsA 1.17.7.4 J Ribosomal protein S1
PFAPIKCO_00921 1.3e-227 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PFAPIKCO_00922 8.5e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PFAPIKCO_00924 3.7e-23 K Acetyltransferase (GNAT) domain
PFAPIKCO_00925 6.9e-111 natA S Domain of unknown function (DUF4162)
PFAPIKCO_00926 1.3e-83 natB CP ABC-type Na efflux pump, permease component
PFAPIKCO_00927 1.8e-95 EG EamA-like transporter family
PFAPIKCO_00928 2.9e-79 yjjH S Calcineurin-like phosphoesterase
PFAPIKCO_00929 7.5e-188 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PFAPIKCO_00930 4.3e-69 lepB 3.4.21.89 U Signal peptidase, peptidase S26
PFAPIKCO_00931 1.8e-116 degV S EDD domain protein, DegV family
PFAPIKCO_00932 3.1e-40 K Transcriptional regulator
PFAPIKCO_00933 5.9e-204 FbpA K Fibronectin-binding protein
PFAPIKCO_00934 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PFAPIKCO_00935 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PFAPIKCO_00936 3.2e-83 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PFAPIKCO_00937 2.2e-39 ypaA S Protein of unknown function (DUF1304)
PFAPIKCO_00939 3.7e-310 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PFAPIKCO_00940 1.9e-167 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PFAPIKCO_00941 0.0 dnaE 2.7.7.7 L DNA polymerase
PFAPIKCO_00942 4.3e-15 S Protein of unknown function (DUF2929)
PFAPIKCO_00943 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PFAPIKCO_00944 4.3e-203 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PFAPIKCO_00945 3.7e-41 XK27_04120 S Putative amino acid metabolism
PFAPIKCO_00946 1.3e-159 iscS 2.8.1.7 E Aminotransferase class V
PFAPIKCO_00947 2.5e-92 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PFAPIKCO_00949 5.8e-81 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PFAPIKCO_00950 1.5e-130 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PFAPIKCO_00951 8.5e-161 nhaC C Na H antiporter NhaC
PFAPIKCO_00952 7e-127 corA P CorA-like Mg2+ transporter protein
PFAPIKCO_00953 4.3e-298 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PFAPIKCO_00954 6.9e-205 hisS 6.1.1.21 J histidyl-tRNA synthetase
PFAPIKCO_00955 8.1e-150 S Tetratricopeptide repeat protein
PFAPIKCO_00956 3.8e-136 EG EamA-like transporter family
PFAPIKCO_00957 4.6e-72 alkD L DNA alkylation repair enzyme
PFAPIKCO_00958 1.1e-183 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PFAPIKCO_00959 7.4e-104 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PFAPIKCO_00960 7.8e-78 trmK 2.1.1.217 S SAM-dependent methyltransferase
PFAPIKCO_00961 2.8e-97 tnp2 L Transposase
PFAPIKCO_00963 6.1e-39
PFAPIKCO_00964 2.9e-256 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PFAPIKCO_00965 6.6e-23 S Family of unknown function (DUF5322)
PFAPIKCO_00966 4.1e-36 rnhA 3.1.26.4 L Ribonuclease HI
PFAPIKCO_00967 2.7e-173 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PFAPIKCO_00968 1.1e-35 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PFAPIKCO_00970 2.7e-87 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PFAPIKCO_00971 2.6e-171 patA 2.6.1.1 E Aminotransferase
PFAPIKCO_00972 8.6e-115 glcR K DeoR C terminal sensor domain
PFAPIKCO_00973 3.3e-98 tnp2 L Transposase
PFAPIKCO_00974 2.4e-143 ppaC 3.6.1.1 C inorganic pyrophosphatase
PFAPIKCO_00975 4.7e-134 K Transcriptional regulator
PFAPIKCO_00976 6.7e-89 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PFAPIKCO_00977 2.3e-85 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PFAPIKCO_00978 3.8e-191 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PFAPIKCO_00979 7.4e-115 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PFAPIKCO_00980 3.5e-204 pyrP F Permease
PFAPIKCO_00981 1.3e-75 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PFAPIKCO_00982 7.3e-129 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PFAPIKCO_00983 3.4e-42 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PFAPIKCO_00984 5.1e-57 3.1.3.18 J HAD-hyrolase-like
PFAPIKCO_00985 2.3e-54 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PFAPIKCO_00986 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PFAPIKCO_00987 6.3e-78 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PFAPIKCO_00988 4.4e-118 prmA J Ribosomal protein L11 methyltransferase
PFAPIKCO_00989 1.7e-42 XK27_03960 S Protein of unknown function (DUF3013)
PFAPIKCO_00990 3e-144 iunH2 3.2.2.1 F nucleoside hydrolase
PFAPIKCO_00991 6.4e-12
PFAPIKCO_00992 2.5e-98 tnp2 L Transposase
PFAPIKCO_00993 5e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PFAPIKCO_00994 1.8e-97 udk 2.7.1.48 F Cytidine monophosphokinase
PFAPIKCO_00995 6.7e-127 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PFAPIKCO_00996 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PFAPIKCO_00997 7.4e-173 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PFAPIKCO_00998 9.1e-43 yodB K Transcriptional regulator, HxlR family
PFAPIKCO_00999 2.1e-67 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PFAPIKCO_01000 7.2e-85 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PFAPIKCO_01004 1.4e-278 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PFAPIKCO_01005 8.4e-45 S Repeat protein
PFAPIKCO_01006 3.1e-100 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PFAPIKCO_01007 5.2e-152 M Exporter of polyketide antibiotics
PFAPIKCO_01008 2.4e-203 G PTS system Galactitol-specific IIC component
PFAPIKCO_01009 8.8e-119 sip L Belongs to the 'phage' integrase family
PFAPIKCO_01010 7.1e-12 bldD K Helix-turn-helix XRE-family like proteins
PFAPIKCO_01012 1e-07 S Helix-turn-helix domain
PFAPIKCO_01013 2.9e-45 S Phage regulatory protein Rha (Phage_pRha)
PFAPIKCO_01020 1e-46 L Bifunctional DNA primase/polymerase, N-terminal
PFAPIKCO_01021 1e-76 S DNA primase
PFAPIKCO_01023 9.7e-13
PFAPIKCO_01025 1.8e-208 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PFAPIKCO_01026 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PFAPIKCO_01027 5.7e-89 L PFAM Integrase catalytic region
PFAPIKCO_01028 1.6e-30 L Helix-turn-helix domain
PFAPIKCO_01031 1.4e-152 V Pfam:Methyltransf_26
PFAPIKCO_01032 3.4e-225 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PFAPIKCO_01033 6.1e-153 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PFAPIKCO_01034 2.9e-25 L Transposase domain (DUF772)
PFAPIKCO_01035 4.3e-98 tnp2 L Transposase
PFAPIKCO_01036 8e-91 infB UW LPXTG-motif cell wall anchor domain protein
PFAPIKCO_01037 1.4e-51
PFAPIKCO_01038 1.9e-107 L Transposase
PFAPIKCO_01039 1.8e-82 L Transposase, IS116 IS110 IS902 family
PFAPIKCO_01040 1.5e-32 dprA LU DNA protecting protein DprA
PFAPIKCO_01041 4.9e-97 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PFAPIKCO_01042 4.7e-133 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PFAPIKCO_01043 3.6e-24 yozE S Belongs to the UPF0346 family
PFAPIKCO_01044 5.7e-53 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PFAPIKCO_01045 6.5e-80 ypmR E GDSL-like Lipase/Acylhydrolase
PFAPIKCO_01047 3.3e-103 S Aldo keto reductase
PFAPIKCO_01048 1.1e-35 K helix_turn_helix, mercury resistance
PFAPIKCO_01049 2.5e-134 yvgN C Aldo keto reductase
PFAPIKCO_01050 3.2e-57 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PFAPIKCO_01051 4.4e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PFAPIKCO_01052 7.7e-277 yfmR S ABC transporter, ATP-binding protein
PFAPIKCO_01053 6.6e-133 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PFAPIKCO_01054 1.1e-107 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PFAPIKCO_01055 1.3e-106 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFAPIKCO_01056 3.9e-68 xerD L Phage integrase, N-terminal SAM-like domain
PFAPIKCO_01058 1.8e-56 yqeY S YqeY-like protein
PFAPIKCO_01059 4.7e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PFAPIKCO_01060 1.1e-115 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PFAPIKCO_01063 5.8e-100 epsJ1 M Glycosyltransferase like family 2
PFAPIKCO_01064 3.7e-84 M Glycosyltransferase sugar-binding region containing DXD motif
PFAPIKCO_01065 2.1e-92 M transferase activity, transferring glycosyl groups
PFAPIKCO_01066 9.6e-126 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PFAPIKCO_01067 4.5e-78 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PFAPIKCO_01068 1.5e-83 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PFAPIKCO_01069 5.1e-56 dnaD L DnaD domain protein
PFAPIKCO_01070 7.6e-236 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PFAPIKCO_01071 3.1e-143 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PFAPIKCO_01072 1.4e-36 ypmB S Protein conserved in bacteria
PFAPIKCO_01073 8.2e-227 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PFAPIKCO_01074 2.8e-94 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PFAPIKCO_01075 3.7e-118 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PFAPIKCO_01076 6.7e-137 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PFAPIKCO_01077 1.3e-113 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PFAPIKCO_01078 1.4e-104 holA 2.7.7.7 L DNA polymerase III delta subunit
PFAPIKCO_01079 7.2e-157 comEC S Competence protein ComEC
PFAPIKCO_01080 2e-69 comEB 3.5.4.12 F ComE operon protein 2
PFAPIKCO_01081 2.2e-45 comEA L Competence protein ComEA
PFAPIKCO_01082 5.8e-268 argS 6.1.1.19 J Arginyl-tRNA synthetase
PFAPIKCO_01083 4.7e-59 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PFAPIKCO_01084 2.2e-20
PFAPIKCO_01086 5e-122 K LysR substrate binding domain
PFAPIKCO_01087 7.5e-195 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PFAPIKCO_01088 2.7e-106 S Acyltransferase family
PFAPIKCO_01089 3.7e-97 tnp2 L Transposase
PFAPIKCO_01090 6e-161 purD 6.3.4.13 F Belongs to the GARS family
PFAPIKCO_01091 1.4e-233 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PFAPIKCO_01092 2.6e-74 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PFAPIKCO_01093 7.7e-138 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PFAPIKCO_01094 5.5e-227 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PFAPIKCO_01095 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PFAPIKCO_01096 1.5e-102 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PFAPIKCO_01097 4.8e-30 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PFAPIKCO_01098 2.9e-96 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PFAPIKCO_01099 1.8e-131 ylbL T Belongs to the peptidase S16 family
PFAPIKCO_01100 4e-49 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PFAPIKCO_01101 1e-72 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PFAPIKCO_01102 2.4e-17 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PFAPIKCO_01103 2.5e-98 tnp2 L Transposase
PFAPIKCO_01104 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PFAPIKCO_01105 3e-101 ftsW D Belongs to the SEDS family
PFAPIKCO_01106 3.3e-148 manN G system, mannose fructose sorbose family IID component
PFAPIKCO_01107 7e-115 manY G PTS system
PFAPIKCO_01108 3.5e-148 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PFAPIKCO_01109 0.0 typA T GTP-binding protein TypA
PFAPIKCO_01110 4.8e-76 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PFAPIKCO_01111 1.7e-23 yktA S Belongs to the UPF0223 family
PFAPIKCO_01112 7e-31 1.1.1.27 C L-malate dehydrogenase activity
PFAPIKCO_01113 2.2e-86 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PFAPIKCO_01114 7.2e-25
PFAPIKCO_01115 2.5e-22 ykzG S Belongs to the UPF0356 family
PFAPIKCO_01116 1.9e-300 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFAPIKCO_01117 3.9e-249 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PFAPIKCO_01118 1e-197 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PFAPIKCO_01119 1.3e-195 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PFAPIKCO_01120 1.4e-215 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PFAPIKCO_01121 1.8e-18 S Tetratricopeptide repeat
PFAPIKCO_01122 4.2e-266 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PFAPIKCO_01123 1.8e-116 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PFAPIKCO_01124 5.6e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PFAPIKCO_01125 1.8e-32 rpsT J Binds directly to 16S ribosomal RNA
PFAPIKCO_01126 3e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PFAPIKCO_01127 7e-198 yfnA E amino acid
PFAPIKCO_01128 4.4e-61 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
PFAPIKCO_01129 7.3e-114 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PFAPIKCO_01130 1.9e-57 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PFAPIKCO_01131 1.1e-26 ylqC S Belongs to the UPF0109 family
PFAPIKCO_01132 3.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PFAPIKCO_01133 3.2e-203 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PFAPIKCO_01134 1.6e-39 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PFAPIKCO_01135 2.6e-148 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PFAPIKCO_01136 3.1e-207 smc D Required for chromosome condensation and partitioning
PFAPIKCO_01137 1.1e-100 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PFAPIKCO_01138 7e-26 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PFAPIKCO_01139 7.9e-140 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PFAPIKCO_01140 5.2e-247 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PFAPIKCO_01141 1.6e-238 yloV S DAK2 domain fusion protein YloV
PFAPIKCO_01142 4.5e-53 asp S Asp23 family, cell envelope-related function
PFAPIKCO_01143 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PFAPIKCO_01144 2.9e-58 thiN 2.7.6.2 H thiamine pyrophosphokinase
PFAPIKCO_01145 1.8e-111 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PFAPIKCO_01146 1.2e-191 KLT serine threonine protein kinase
PFAPIKCO_01147 1.9e-90 stp 3.1.3.16 T phosphatase
PFAPIKCO_01148 3.4e-154 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PFAPIKCO_01149 9.9e-140 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PFAPIKCO_01150 1.9e-288 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PFAPIKCO_01151 4.4e-121 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PFAPIKCO_01152 2.5e-21 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PFAPIKCO_01153 1.1e-102 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PFAPIKCO_01154 5.6e-94 2.7.1.89 M Phosphotransferase enzyme family
PFAPIKCO_01155 3.5e-26 arsC 1.20.4.1 P Belongs to the ArsC family
PFAPIKCO_01156 6.1e-187 rodA D Belongs to the SEDS family
PFAPIKCO_01157 1.3e-13 S Protein of unknown function (DUF2969)
PFAPIKCO_01158 1.2e-26 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PFAPIKCO_01159 3.4e-167 mbl D Cell shape determining protein MreB Mrl
PFAPIKCO_01160 9.3e-197 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PFAPIKCO_01161 4.1e-15 ywzB S Protein of unknown function (DUF1146)
PFAPIKCO_01162 7.4e-98 tnp2 L Transposase
PFAPIKCO_01163 3.9e-48 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PFAPIKCO_01164 1.7e-236 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PFAPIKCO_01165 1.3e-141 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PFAPIKCO_01166 6.3e-266 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PFAPIKCO_01167 2.7e-57 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PFAPIKCO_01168 2.4e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PFAPIKCO_01169 1.8e-15 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PFAPIKCO_01170 4.5e-97 atpB C it plays a direct role in the translocation of protons across the membrane
PFAPIKCO_01171 5e-100 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PFAPIKCO_01172 7.7e-135 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PFAPIKCO_01173 1.4e-89 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PFAPIKCO_01174 1e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PFAPIKCO_01175 6.8e-86 tdk 2.7.1.21 F thymidine kinase
PFAPIKCO_01176 4.7e-220 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
PFAPIKCO_01177 7.8e-110 cobQ S glutamine amidotransferase
PFAPIKCO_01178 2e-111 ampC V Beta-lactamase
PFAPIKCO_01179 1.5e-31
PFAPIKCO_01180 4.3e-98 tnp2 L Transposase
PFAPIKCO_01181 2.6e-119 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PFAPIKCO_01182 9.2e-206 glnP P ABC transporter
PFAPIKCO_01184 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PFAPIKCO_01185 1.2e-160 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PFAPIKCO_01186 2.6e-274 dnaK O Heat shock 70 kDa protein
PFAPIKCO_01187 4.2e-56 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PFAPIKCO_01188 1.4e-131 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PFAPIKCO_01189 1.9e-95 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PFAPIKCO_01190 1.4e-119 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PFAPIKCO_01191 1.3e-55 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PFAPIKCO_01192 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PFAPIKCO_01193 6.9e-26 ylxQ J ribosomal protein
PFAPIKCO_01194 1.4e-39 ylxR K Protein of unknown function (DUF448)
PFAPIKCO_01195 4.8e-170 nusA K Participates in both transcription termination and antitermination
PFAPIKCO_01196 2.7e-66 rimP J Required for maturation of 30S ribosomal subunits
PFAPIKCO_01197 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PFAPIKCO_01198 5.9e-260 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PFAPIKCO_01199 4.5e-156 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PFAPIKCO_01200 5.1e-102 cdsA 2.7.7.41 S Belongs to the CDS family
PFAPIKCO_01201 3.8e-105 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PFAPIKCO_01202 7.2e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PFAPIKCO_01203 6.3e-115 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PFAPIKCO_01204 2.7e-48 S Domain of unknown function (DUF956)
PFAPIKCO_01205 5.8e-37 ogt 2.1.1.63 H Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PFAPIKCO_01206 1.9e-98 tnp2 L Transposase
PFAPIKCO_01208 2e-247 glnA 6.3.1.2 E glutamine synthetase
PFAPIKCO_01209 1.3e-45 glnR K Transcriptional regulator
PFAPIKCO_01210 1.8e-205 ynbB 4.4.1.1 P aluminum resistance
PFAPIKCO_01211 4.2e-111 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PFAPIKCO_01212 9.7e-17 WQ51_02665 S Protein of unknown function (DUF3042)
PFAPIKCO_01213 2.7e-46 yqhL P Rhodanese-like protein
PFAPIKCO_01214 1.4e-157 glk 2.7.1.2 G Glucokinase
PFAPIKCO_01215 1.5e-25 yqgQ S Bacterial protein of unknown function (DUF910)
PFAPIKCO_01216 1.7e-69 gluP 3.4.21.105 S Peptidase, S54 family
PFAPIKCO_01217 6.2e-38 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PFAPIKCO_01218 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PFAPIKCO_01219 1.8e-19 D nuclear chromosome segregation
PFAPIKCO_01220 1.1e-73 yciQ P membrane protein (DUF2207)
PFAPIKCO_01221 5.4e-44 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PFAPIKCO_01222 1.8e-91 engB D Necessary for normal cell division and for the maintenance of normal septation
PFAPIKCO_01223 5.9e-27 yneF S UPF0154 protein
PFAPIKCO_01224 2.2e-30 ynzC S UPF0291 protein
PFAPIKCO_01225 7.2e-83 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PFAPIKCO_01226 3.3e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFAPIKCO_01227 8.5e-163 recN L May be involved in recombinational repair of damaged DNA
PFAPIKCO_01228 6.6e-49 argR K Regulates arginine biosynthesis genes
PFAPIKCO_01229 1.2e-120 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PFAPIKCO_01230 1.8e-82 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PFAPIKCO_01231 1.2e-16 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PFAPIKCO_01232 6.8e-147 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PFAPIKCO_01233 3e-103 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PFAPIKCO_01234 4.2e-36 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PFAPIKCO_01235 3.7e-46 yqhY S Asp23 family, cell envelope-related function
PFAPIKCO_01236 2.1e-94 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PFAPIKCO_01237 2.2e-41 dut S dUTPase
PFAPIKCO_01238 7.2e-117
PFAPIKCO_01239 2.1e-104
PFAPIKCO_01240 1.4e-114 M Glycosyl hydrolases family 25
PFAPIKCO_01241 2.7e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
PFAPIKCO_01247 3.1e-07 N Bacterial Ig-like domain 2
PFAPIKCO_01248 1.1e-27 S Calcineurin-like phosphoesterase
PFAPIKCO_01250 1.9e-99 M Prophage endopeptidase tail
PFAPIKCO_01251 4e-80 M Prophage endopeptidase tail
PFAPIKCO_01252 6e-78 S Phage tail protein
PFAPIKCO_01253 1.5e-54 M Phage tail tape measure protein TP901
PFAPIKCO_01254 6.5e-72 M Phage tail tape measure protein TP901
PFAPIKCO_01256 6.2e-15 S Phage tail assembly chaperone protein, TAC
PFAPIKCO_01257 2e-46
PFAPIKCO_01258 1.8e-18
PFAPIKCO_01259 1.6e-32
PFAPIKCO_01260 2.9e-11
PFAPIKCO_01261 1.6e-34 S Phage gp6-like head-tail connector protein
PFAPIKCO_01262 7.7e-106 gpG
PFAPIKCO_01263 2e-13 S Domain of unknown function (DUF4355)
PFAPIKCO_01266 2.3e-62 S Phage Mu protein F like protein
PFAPIKCO_01267 1.3e-163 S Phage portal protein, SPP1 Gp6-like
PFAPIKCO_01268 3.1e-133 ps334 S Terminase-like family
PFAPIKCO_01269 1.7e-39 L transposase activity
PFAPIKCO_01270 8.8e-36 queT S QueT transporter
PFAPIKCO_01271 1.8e-23 S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PFAPIKCO_01272 3.5e-43 2.1.1.72 KL DNA methylase
PFAPIKCO_01273 8.3e-33 arpU S Phage transcriptional regulator, ArpU family
PFAPIKCO_01276 4.3e-08
PFAPIKCO_01282 1.1e-104 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
PFAPIKCO_01283 1.6e-21 S HNH endonuclease
PFAPIKCO_01284 3.8e-32 rusA L Endodeoxyribonuclease RusA
PFAPIKCO_01287 2e-25 S sequence-specific DNA binding
PFAPIKCO_01289 2.2e-31 dnaC L IstB-like ATP binding protein
PFAPIKCO_01290 5.7e-24 L Psort location Cytoplasmic, score
PFAPIKCO_01292 4.5e-19
PFAPIKCO_01294 6.8e-89 S PDDEXK-like domain of unknown function (DUF3799)
PFAPIKCO_01295 1.3e-75 recT L RecT family
PFAPIKCO_01298 2.8e-18
PFAPIKCO_01299 8.6e-51 S DNA binding
PFAPIKCO_01300 6.1e-48 L Psort location Cytoplasmic, score
PFAPIKCO_01302 6.2e-28 S sequence-specific DNA binding
PFAPIKCO_01303 3.7e-09 E Zn peptidase
PFAPIKCO_01304 3.3e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFAPIKCO_01306 6.9e-10
PFAPIKCO_01308 7.9e-36
PFAPIKCO_01309 5.2e-95 sip L Belongs to the 'phage' integrase family
PFAPIKCO_01310 1.5e-137 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PFAPIKCO_01311 9.7e-24 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PFAPIKCO_01312 6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PFAPIKCO_01313 1.3e-167 arlS 2.7.13.3 T Histidine kinase
PFAPIKCO_01314 3.1e-111 K response regulator
PFAPIKCO_01316 1e-107 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PFAPIKCO_01317 1.2e-225 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PFAPIKCO_01318 9.3e-158 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PFAPIKCO_01319 4.1e-57 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PFAPIKCO_01320 1.3e-91 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PFAPIKCO_01321 6.9e-37
PFAPIKCO_01322 4.8e-97 tnp2 L Transposase
PFAPIKCO_01323 2.7e-128 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PFAPIKCO_01324 1.9e-128 rpsB J Belongs to the universal ribosomal protein uS2 family
PFAPIKCO_01325 1.5e-27 yazA L GIY-YIG catalytic domain protein
PFAPIKCO_01326 1.2e-92 yabB 2.1.1.223 L Methyltransferase small domain
PFAPIKCO_01327 1.2e-88 plsC 2.3.1.51 I Acyltransferase
PFAPIKCO_01328 1.9e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PFAPIKCO_01329 1e-56 yceD S Uncharacterized ACR, COG1399
PFAPIKCO_01330 1.3e-122 ylbM S Belongs to the UPF0348 family
PFAPIKCO_01331 9.4e-82 H Nodulation protein S (NodS)
PFAPIKCO_01332 1.5e-48 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PFAPIKCO_01333 1e-70 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PFAPIKCO_01334 3.5e-77 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PFAPIKCO_01335 6e-30 yhbY J RNA-binding protein
PFAPIKCO_01336 6.4e-15 yqeH S Ribosome biogenesis GTPase YqeH
PFAPIKCO_01337 8.3e-132 yqeH S Ribosome biogenesis GTPase YqeH
PFAPIKCO_01338 2.5e-71 yqeG S HAD phosphatase, family IIIA
PFAPIKCO_01339 5.6e-98 tnp2 L Transposase
PFAPIKCO_01340 7.7e-53 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PFAPIKCO_01341 1.4e-24 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PFAPIKCO_01342 1.3e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PFAPIKCO_01343 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PFAPIKCO_01344 9.7e-108 dnaI L Primosomal protein DnaI
PFAPIKCO_01345 1.6e-79 dnaB L replication initiation and membrane attachment
PFAPIKCO_01346 6.1e-66 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PFAPIKCO_01347 1.6e-50 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PFAPIKCO_01348 6.2e-106 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PFAPIKCO_01349 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PFAPIKCO_01350 3e-69 ybhL S Belongs to the BI1 family
PFAPIKCO_01351 2.5e-61 phaJ I N-terminal half of MaoC dehydratase
PFAPIKCO_01352 3.8e-222 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PFAPIKCO_01353 8.4e-238 sftA D Belongs to the FtsK SpoIIIE SftA family
PFAPIKCO_01354 5e-122 sip L Belongs to the 'phage' integrase family
PFAPIKCO_01355 2.5e-10 bldD K Helix-turn-helix XRE-family like proteins
PFAPIKCO_01356 1.7e-09 S Helix-turn-helix domain
PFAPIKCO_01357 8.8e-44 S Phage regulatory protein Rha (Phage_pRha)
PFAPIKCO_01364 2.8e-16 L DnaD domain protein
PFAPIKCO_01365 1.1e-08
PFAPIKCO_01368 8.9e-76 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PFAPIKCO_01369 4e-45 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PFAPIKCO_01371 3.9e-100 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PFAPIKCO_01372 1.6e-98 ytmP 2.7.1.89 M Choline/ethanolamine kinase
PFAPIKCO_01373 2.2e-72 ecsB U ABC transporter
PFAPIKCO_01374 9.8e-95 ecsA V ABC transporter, ATP-binding protein
PFAPIKCO_01375 7e-53 hit FG histidine triad
PFAPIKCO_01377 2.5e-113 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PFAPIKCO_01378 7.3e-127 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
PFAPIKCO_01379 2e-21 yheA S Belongs to the UPF0342 family
PFAPIKCO_01380 6.6e-285 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PFAPIKCO_01382 2.6e-86 ykuT M mechanosensitive ion channel
PFAPIKCO_01383 2.4e-177 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PFAPIKCO_01384 3e-61 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PFAPIKCO_01385 5.8e-45 ykuL S CBS domain
PFAPIKCO_01386 1.3e-118 gla U Major intrinsic protein
PFAPIKCO_01387 6e-302 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PFAPIKCO_01388 9.1e-240 pgi 5.3.1.9 G Belongs to the GPI family
PFAPIKCO_01389 1.3e-99 tnp2 L Transposase
PFAPIKCO_01390 5.1e-231 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PFAPIKCO_01391 7.1e-109 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PFAPIKCO_01392 6.7e-102 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PFAPIKCO_01393 8e-125 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PFAPIKCO_01394 4.2e-216 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PFAPIKCO_01395 3e-64 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PFAPIKCO_01396 4.6e-47 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PFAPIKCO_01397 6.2e-195 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PFAPIKCO_01398 4.9e-99 IQ reductase
PFAPIKCO_01399 2.1e-102 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PFAPIKCO_01400 2.2e-27 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PFAPIKCO_01401 2.4e-101 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PFAPIKCO_01402 4.2e-61 marR K Transcriptional regulator, MarR family
PFAPIKCO_01403 9.8e-66 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PFAPIKCO_01404 4e-36
PFAPIKCO_01406 3.3e-192 pepV 3.5.1.18 E dipeptidase PepV
PFAPIKCO_01407 8.3e-82 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PFAPIKCO_01408 1.5e-60 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PFAPIKCO_01409 8.3e-187 ytgP S Polysaccharide biosynthesis protein
PFAPIKCO_01410 2.4e-192 cycA E Amino acid permease
PFAPIKCO_01411 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PFAPIKCO_01412 7.4e-177 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PFAPIKCO_01414 7.4e-98 tnp2 L Transposase
PFAPIKCO_01424 2.1e-07
PFAPIKCO_01434 2.5e-22
PFAPIKCO_01435 8.8e-50 yugI 5.3.1.9 J general stress protein
PFAPIKCO_01436 1e-94 trxB2 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PFAPIKCO_01437 3e-92 dedA S SNARE associated Golgi protein
PFAPIKCO_01438 6e-32 S Protein of unknown function (DUF1461)
PFAPIKCO_01439 2.9e-113 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PFAPIKCO_01440 1.9e-53 yutD S Protein of unknown function (DUF1027)
PFAPIKCO_01441 1.5e-56 S Calcineurin-like phosphoesterase
PFAPIKCO_01442 9.3e-184 cycA E Amino acid permease
PFAPIKCO_01443 5.8e-98 ytxK 2.1.1.72 L N-6 DNA Methylase
PFAPIKCO_01445 9.4e-11 S Putative Competence protein ComGF
PFAPIKCO_01447 1.1e-13
PFAPIKCO_01448 3.6e-27 comGC U competence protein ComGC
PFAPIKCO_01449 4.4e-98 comGB NU type II secretion system
PFAPIKCO_01450 1.1e-120 comGA NU Type II IV secretion system protein
PFAPIKCO_01451 4.6e-102 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PFAPIKCO_01452 1.9e-119 yebC K Transcriptional regulatory protein
PFAPIKCO_01453 3.7e-42 S VanZ like family
PFAPIKCO_01454 1.3e-158 ccpA K catabolite control protein A
PFAPIKCO_01455 1.3e-172 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PFAPIKCO_01456 6.7e-14
PFAPIKCO_01459 4.5e-75 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PFAPIKCO_01460 2.7e-34 K helix_turn_helix, Arsenical Resistance Operon Repressor
PFAPIKCO_01461 1.2e-64 hly S protein, hemolysin III
PFAPIKCO_01462 2.8e-40 M1-874 K Domain of unknown function (DUF1836)
PFAPIKCO_01463 9.4e-84 S membrane
PFAPIKCO_01464 1.1e-79 S VIT family
PFAPIKCO_01465 1.8e-148 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PFAPIKCO_01466 2.7e-56 P Plays a role in the regulation of phosphate uptake
PFAPIKCO_01467 4.7e-116 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PFAPIKCO_01468 4.5e-114 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PFAPIKCO_01469 5.1e-122 pstA P Phosphate transport system permease protein PstA
PFAPIKCO_01470 3.2e-119 pstC P probably responsible for the translocation of the substrate across the membrane
PFAPIKCO_01471 1.4e-97 pstS P Phosphate
PFAPIKCO_01472 3.9e-41 yjbH Q Thioredoxin
PFAPIKCO_01473 2.8e-97 tnp2 L Transposase
PFAPIKCO_01474 9.4e-232 pepF E oligoendopeptidase F
PFAPIKCO_01475 1.2e-67 coiA 3.6.4.12 S Competence protein
PFAPIKCO_01476 7.4e-98 tnp2 L Transposase
PFAPIKCO_01477 9.2e-48 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PFAPIKCO_01478 8.2e-219 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
PFAPIKCO_01484 5.1e-08
PFAPIKCO_01491 8.6e-23
PFAPIKCO_01494 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PFAPIKCO_01495 6.8e-26 ykuJ S Protein of unknown function (DUF1797)
PFAPIKCO_01496 5.1e-126 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PFAPIKCO_01497 1.3e-126 cpoA GT4 M Glycosyltransferase, group 1 family protein
PFAPIKCO_01498 7.4e-161 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PFAPIKCO_01499 2.6e-284 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PFAPIKCO_01500 9.7e-37 ptsH G phosphocarrier protein HPR
PFAPIKCO_01501 1.5e-15
PFAPIKCO_01502 0.0 clpE O Belongs to the ClpA ClpB family
PFAPIKCO_01503 1.9e-22 XK27_09445 S Domain of unknown function (DUF1827)
PFAPIKCO_01504 2.9e-105 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
PFAPIKCO_01505 0.0 rafA 3.2.1.22 G alpha-galactosidase
PFAPIKCO_01506 7e-201 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PFAPIKCO_01507 2.3e-163 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PFAPIKCO_01508 4.5e-179 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PFAPIKCO_01509 2.9e-110 galR K Transcriptional regulator
PFAPIKCO_01510 1.7e-287 lacS G Transporter
PFAPIKCO_01511 0.0 lacL 3.2.1.23 G -beta-galactosidase
PFAPIKCO_01512 5.2e-279 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PFAPIKCO_01513 3e-108 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PFAPIKCO_01514 3.2e-157 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PFAPIKCO_01515 6.9e-92 yueF S AI-2E family transporter
PFAPIKCO_01516 2.6e-97 ygaC J Belongs to the UPF0374 family
PFAPIKCO_01517 1.6e-191 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PFAPIKCO_01518 6.9e-70 recX 2.4.1.337 GT4 S Regulatory protein RecX
PFAPIKCO_01519 8.9e-19 yvrI K RNA polymerase sigma factor, sigma-70 family
PFAPIKCO_01520 2e-22 S Cytochrome B5
PFAPIKCO_01521 6e-49 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain (presumed)
PFAPIKCO_01522 6.4e-59
PFAPIKCO_01523 3.7e-43 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PFAPIKCO_01524 3.6e-154 nrnB S DHHA1 domain
PFAPIKCO_01525 3.7e-90 yunF F Protein of unknown function DUF72
PFAPIKCO_01526 9e-49 ndoA L Toxic component of a toxin-antitoxin (TA) module
PFAPIKCO_01527 5.4e-13
PFAPIKCO_01528 2.8e-146 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PFAPIKCO_01529 1.6e-30 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PFAPIKCO_01530 1e-207 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PFAPIKCO_01531 6.9e-179 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PFAPIKCO_01532 2.9e-65 S Uncharacterized protein conserved in bacteria (DUF2263)
PFAPIKCO_01533 6e-180 pbuG S permease
PFAPIKCO_01535 9.4e-80 S Cell surface protein
PFAPIKCO_01537 3.8e-257 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
PFAPIKCO_01538 8.2e-61
PFAPIKCO_01539 1.4e-40 rpmE2 J Ribosomal protein L31
PFAPIKCO_01540 4.1e-189 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PFAPIKCO_01541 1e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PFAPIKCO_01543 3.3e-289 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PFAPIKCO_01544 2.9e-41 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PFAPIKCO_01545 3.1e-32 ywiB S Domain of unknown function (DUF1934)
PFAPIKCO_01546 1.3e-85 yfeJ 6.3.5.2 F glutamine amidotransferase
PFAPIKCO_01547 2.5e-58 tlpA2 L Transposase IS200 like
PFAPIKCO_01548 3.9e-160 L transposase, IS605 OrfB family
PFAPIKCO_01549 1.2e-204 ywfO S HD domain protein
PFAPIKCO_01550 8e-90 S hydrolase
PFAPIKCO_01551 6.5e-104 ydcZ S Putative inner membrane exporter, YdcZ
PFAPIKCO_01552 4.3e-98 tnp2 L Transposase
PFAPIKCO_01553 1.1e-18
PFAPIKCO_01554 4.1e-73
PFAPIKCO_01556 2.7e-38 L COGs COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
PFAPIKCO_01557 1e-22
PFAPIKCO_01558 1.1e-55 spoVK O ATPase family associated with various cellular activities (AAA)
PFAPIKCO_01560 4.9e-86 S overlaps another CDS with the same product name
PFAPIKCO_01561 5.3e-121 S overlaps another CDS with the same product name
PFAPIKCO_01562 1e-99 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PFAPIKCO_01563 1.8e-35 ytkL S Belongs to the UPF0173 family
PFAPIKCO_01564 1e-13 ytkL S Beta-lactamase superfamily domain
PFAPIKCO_01565 2e-289 ybiT S ABC transporter, ATP-binding protein
PFAPIKCO_01566 5.6e-77 2.4.2.3 F Phosphorylase superfamily
PFAPIKCO_01567 1.7e-24
PFAPIKCO_01568 1.2e-112 dkg S reductase
PFAPIKCO_01570 1.5e-20 rimL 1.1.1.25 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFAPIKCO_01571 2.3e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PFAPIKCO_01572 2.3e-193 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PFAPIKCO_01573 5.6e-47 EGP Transmembrane secretion effector
PFAPIKCO_01574 1.6e-97 tnp2 L Transposase
PFAPIKCO_01575 5.2e-137 purR 2.4.2.7 F pur operon repressor
PFAPIKCO_01576 7.2e-19 S YCII-related domain
PFAPIKCO_01577 7.9e-70 ywrO S Flavodoxin-like fold
PFAPIKCO_01578 6.6e-53 adhR K helix_turn_helix, mercury resistance
PFAPIKCO_01579 5.2e-185 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PFAPIKCO_01581 1.4e-102 pfoS S Phosphotransferase system, EIIC
PFAPIKCO_01582 6.9e-128 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFAPIKCO_01583 4.4e-150 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PFAPIKCO_01584 3.8e-197 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PFAPIKCO_01585 1.6e-199 argH 4.3.2.1 E argininosuccinate lyase
PFAPIKCO_01586 3.1e-215 L Probable transposase
PFAPIKCO_01588 6.9e-116 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PFAPIKCO_01589 6.6e-46 argR K Regulates arginine biosynthesis genes
PFAPIKCO_01590 1.6e-133 arcT 2.6.1.1 E Cys/Met metabolism PLP-dependent enzyme
PFAPIKCO_01591 4e-76 S Alpha/beta hydrolase of unknown function (DUF915)
PFAPIKCO_01592 1.2e-22 veg S Biofilm formation stimulator VEG
PFAPIKCO_01593 4.1e-132 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PFAPIKCO_01594 3.4e-87 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PFAPIKCO_01595 9.2e-104 tatD L hydrolase, TatD family
PFAPIKCO_01596 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PFAPIKCO_01597 5.6e-127
PFAPIKCO_01598 3.5e-153 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PFAPIKCO_01599 1.6e-42 VPA1512 ET Bacterial extracellular solute-binding proteins, family 3
PFAPIKCO_01600 2.3e-31 K Transcriptional regulator
PFAPIKCO_01601 3.8e-35 ybhR V ABC transporter
PFAPIKCO_01602 2.1e-54 ybhR V ABC transporter
PFAPIKCO_01603 3.2e-82 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
PFAPIKCO_01604 2.7e-102 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PFAPIKCO_01605 4.4e-170 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PFAPIKCO_01606 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_01607 6e-127 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PFAPIKCO_01608 9.8e-271 helD 3.6.4.12 L DNA helicase
PFAPIKCO_01610 1.3e-114 htpX O Belongs to the peptidase M48B family
PFAPIKCO_01611 8.7e-72 lemA S LemA family
PFAPIKCO_01612 1.1e-54 L phosphatase homologous to the C-terminal domain of histone macroH2A1
PFAPIKCO_01613 3.2e-45 yjcF K protein acetylation
PFAPIKCO_01615 1.8e-251 yfiC V ABC transporter
PFAPIKCO_01616 1.3e-66 lmrA V ABC transporter, ATP-binding protein
PFAPIKCO_01617 1.4e-146 lmrA V ABC transporter, ATP-binding protein
PFAPIKCO_01618 4.5e-35 K Bacterial regulatory proteins, tetR family
PFAPIKCO_01619 2.1e-245 yhcA V ABC transporter, ATP-binding protein
PFAPIKCO_01620 2.6e-223 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PFAPIKCO_01621 1e-146 G Transporter, major facilitator family protein
PFAPIKCO_01622 7.2e-89 lacX 5.1.3.3 G Aldose 1-epimerase
PFAPIKCO_01623 4.4e-142 hpk31 2.7.13.3 T Histidine kinase
PFAPIKCO_01624 3.7e-112 K response regulator
PFAPIKCO_01625 4e-90 patB 4.4.1.8 E Aminotransferase, class I
PFAPIKCO_01626 1.3e-91 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PFAPIKCO_01627 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PFAPIKCO_01628 1.3e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PFAPIKCO_01629 6.1e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PFAPIKCO_01630 3.3e-23 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
PFAPIKCO_01631 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFAPIKCO_01632 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PFAPIKCO_01633 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PFAPIKCO_01634 1.6e-55 ctsR K Belongs to the CtsR family
PFAPIKCO_01635 6.7e-99 tnp2 L Transposase
PFAPIKCO_01637 1.1e-119 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PFAPIKCO_01638 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PFAPIKCO_01639 6.3e-159 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PFAPIKCO_01640 2.1e-185 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PFAPIKCO_01641 2.2e-131 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PFAPIKCO_01651 2.5e-22
PFAPIKCO_01654 3.6e-190 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PFAPIKCO_01655 5.5e-243 lysP E amino acid
PFAPIKCO_01656 3.1e-69 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
PFAPIKCO_01657 8.6e-272 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PFAPIKCO_01658 9.2e-14 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PFAPIKCO_01659 3.2e-57 lssY 3.6.1.27 I phosphatidate phosphatase activity
PFAPIKCO_01660 7.6e-83 lysR5 K LysR substrate binding domain
PFAPIKCO_01661 2.9e-119 yxaA S membrane transporter protein
PFAPIKCO_01662 2.6e-32 ywjH S Protein of unknown function (DUF1634)
PFAPIKCO_01663 3.2e-118 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PFAPIKCO_01664 1.6e-226 pipD E Dipeptidase
PFAPIKCO_01665 1.4e-21 K helix_turn_helix multiple antibiotic resistance protein
PFAPIKCO_01666 4.4e-165 EGP Major facilitator Superfamily
PFAPIKCO_01667 4.7e-81 S L,D-transpeptidase catalytic domain
PFAPIKCO_01668 1.6e-141 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PFAPIKCO_01669 1.5e-144 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PFAPIKCO_01670 3.6e-26 ydiI Q Thioesterase superfamily
PFAPIKCO_01671 1.2e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
PFAPIKCO_01672 1.3e-147 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PFAPIKCO_01673 8.4e-114 degV S EDD domain protein, DegV family
PFAPIKCO_01674 4.5e-226 cadA P P-type ATPase
PFAPIKCO_01675 3.1e-254 E Amino acid permease
PFAPIKCO_01676 2.7e-83 S Membrane
PFAPIKCO_01677 2e-49 cps3F
PFAPIKCO_01678 2.9e-303 fruA 2.7.1.202 GT Phosphotransferase System
PFAPIKCO_01679 4.1e-151 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PFAPIKCO_01680 9e-88 fruR K DeoR C terminal sensor domain
PFAPIKCO_01681 1.4e-219 XK27_08635 S UPF0210 protein
PFAPIKCO_01682 1.2e-26 gcvR T Belongs to the UPF0237 family
PFAPIKCO_01683 6.1e-39
PFAPIKCO_01684 4.1e-76 E GDSL-like Lipase/Acylhydrolase family
PFAPIKCO_01685 1.4e-56 S Protein of unknown function (DUF975)
PFAPIKCO_01686 7.3e-149 lplA 6.3.1.20 H Lipoate-protein ligase
PFAPIKCO_01687 4e-230 lpdA 1.8.1.4 C Dehydrogenase
PFAPIKCO_01688 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PFAPIKCO_01689 5.7e-167 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PFAPIKCO_01690 4.7e-178 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PFAPIKCO_01691 0.0 3.5.1.28 UW LPXTG-motif cell wall anchor domain protein
PFAPIKCO_01693 1.9e-58 S Protein of unknown function (DUF4256)
PFAPIKCO_01694 1.9e-128 metQ M Belongs to the nlpA lipoprotein family
PFAPIKCO_01695 2.4e-31 metI U ABC transporter permease
PFAPIKCO_01696 8.1e-151 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PFAPIKCO_01698 1.1e-41 L PFAM transposase IS200-family protein
PFAPIKCO_01699 1.1e-63 hsdS-1 3.1.21.3 L Belongs to the 'phage' integrase family
PFAPIKCO_01700 2.7e-138 L Belongs to the 'phage' integrase family
PFAPIKCO_01701 1.4e-244 hsdM 2.1.1.72 V HsdM N-terminal domain
PFAPIKCO_01702 4e-101 3.1.21.3 V Type I restriction modification DNA specificity domain
PFAPIKCO_01703 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PFAPIKCO_01704 2.2e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
PFAPIKCO_01705 9.7e-265 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
PFAPIKCO_01706 1.8e-171 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PFAPIKCO_01707 7.8e-107 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PFAPIKCO_01708 3.9e-84 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
PFAPIKCO_01709 3e-84 drgA C nitroreductase
PFAPIKCO_01710 2e-144 2.1.1.14 E methionine synthase, vitamin-B12 independent
PFAPIKCO_01711 1e-45 yphJ 4.1.1.44 S decarboxylase
PFAPIKCO_01712 5.3e-58 yphH S Cupin domain
PFAPIKCO_01713 4.9e-39 C Flavodoxin
PFAPIKCO_01715 1.9e-91 L Transposase, IS605 OrfB family
PFAPIKCO_01716 1e-54 tlpA2 L Transposase IS200 like
PFAPIKCO_01718 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_01720 2.6e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PFAPIKCO_01723 9.9e-180 proV E ABC transporter, ATP-binding protein
PFAPIKCO_01724 2.4e-184 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PFAPIKCO_01725 1.1e-67 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PFAPIKCO_01727 2e-49 L Helix-turn-helix domain
PFAPIKCO_01728 1.1e-45 L hmm pf00665
PFAPIKCO_01729 1.4e-67 spx4 1.20.4.1 P ArsC family
PFAPIKCO_01730 1.8e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PFAPIKCO_01731 2.7e-228 baeS 2.7.13.3 T Histidine kinase
PFAPIKCO_01732 5e-117 K response regulator
PFAPIKCO_01733 8.5e-34 3.2.1.23 S Domain of unknown function DUF302
PFAPIKCO_01734 1.3e-16 3.2.1.23 S Domain of unknown function DUF302
PFAPIKCO_01735 2.4e-40 S membrane protein (DUF2078)
PFAPIKCO_01736 0.0 3.6.3.4 P haloacid dehalogenase-like hydrolase
PFAPIKCO_01737 1.2e-79 copY K Penicillinase repressor
PFAPIKCO_01738 9.3e-54 S CAAX protease self-immunity
PFAPIKCO_01739 4.4e-102 pgm3 G phosphoglycerate mutase
PFAPIKCO_01740 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PFAPIKCO_01741 5.5e-224 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PFAPIKCO_01742 6.3e-55 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PFAPIKCO_01743 1.1e-67 M ErfK YbiS YcfS YnhG
PFAPIKCO_01744 5.2e-107 XK27_08845 S ABC transporter, ATP-binding protein
PFAPIKCO_01745 4.3e-113 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PFAPIKCO_01746 3.5e-132 ABC-SBP S ABC transporter
PFAPIKCO_01747 1.7e-159 potD P ABC transporter
PFAPIKCO_01748 1.3e-103 potC U Binding-protein-dependent transport system inner membrane component
PFAPIKCO_01749 1.9e-120 potB P ABC transporter permease
PFAPIKCO_01750 3.1e-166 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PFAPIKCO_01751 7.4e-100 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PFAPIKCO_01752 5.7e-261 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
PFAPIKCO_01753 8.9e-236 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PFAPIKCO_01754 5.1e-13 S Enterocin A Immunity
PFAPIKCO_01756 2.2e-16 pspC KT PspC domain
PFAPIKCO_01757 3.1e-16 S Putative adhesin
PFAPIKCO_01758 3.2e-19 XK27_06920 S Protein of unknown function (DUF1700)
PFAPIKCO_01759 8.1e-38 K transcriptional regulator PadR family
PFAPIKCO_01760 1.3e-45 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PFAPIKCO_01761 5.2e-75 ung2 3.2.2.27 L Uracil-DNA glycosylase
PFAPIKCO_01762 1.6e-163 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PFAPIKCO_01763 2.6e-128 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PFAPIKCO_01764 4.6e-70 mltD CBM50 M NlpC P60 family protein
PFAPIKCO_01765 7.4e-98 tnp2 L Transposase
PFAPIKCO_01766 3.2e-52 manO S Domain of unknown function (DUF956)
PFAPIKCO_01767 4.7e-147 manN G system, mannose fructose sorbose family IID component
PFAPIKCO_01768 6.4e-116 manY G PTS system sorbose-specific iic component
PFAPIKCO_01769 6.9e-152 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PFAPIKCO_01770 2.4e-80 rbsB G sugar-binding domain protein
PFAPIKCO_01771 2.3e-99 baeS T Histidine kinase
PFAPIKCO_01772 3.9e-79 baeR K Bacterial regulatory proteins, luxR family
PFAPIKCO_01773 1.8e-120 G Bacterial extracellular solute-binding protein
PFAPIKCO_01774 3.1e-71 S Protein of unknown function (DUF554)
PFAPIKCO_01775 2.5e-38 yaeR E glyoxalase bleomycin resistance protein dioxygenase
PFAPIKCO_01776 1.2e-31 merR K MerR HTH family regulatory protein
PFAPIKCO_01777 4.7e-197 lmrB EGP Major facilitator Superfamily
PFAPIKCO_01778 4.5e-33 S Domain of unknown function (DUF4811)
PFAPIKCO_01779 2.2e-60 yceE S haloacid dehalogenase-like hydrolase
PFAPIKCO_01780 7.4e-39 glcR K DeoR C terminal sensor domain
PFAPIKCO_01781 1.3e-31 glcR K DeoR C terminal sensor domain
PFAPIKCO_01782 1.7e-91 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PFAPIKCO_01783 9.8e-176 lmrB EGP Major facilitator Superfamily
PFAPIKCO_01784 2.1e-54 bioY S BioY family
PFAPIKCO_01785 6.9e-94 S Predicted membrane protein (DUF2207)
PFAPIKCO_01786 1.4e-19
PFAPIKCO_01787 1.5e-37 M Glycosyltransferase group 2 family protein
PFAPIKCO_01788 5.7e-54 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PFAPIKCO_01789 2.4e-57 ktrA P TrkA-N domain
PFAPIKCO_01790 7.1e-115 ntpJ P Potassium uptake protein
PFAPIKCO_01791 9.1e-184 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PFAPIKCO_01792 6.1e-282 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
PFAPIKCO_01793 3.5e-216 scrB 3.2.1.26 GH32 G invertase
PFAPIKCO_01794 3.9e-147 scrR K helix_turn _helix lactose operon repressor
PFAPIKCO_01795 8.6e-23
PFAPIKCO_01796 1.9e-168 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PFAPIKCO_01797 2.1e-210 glnP P ABC transporter
PFAPIKCO_01799 1.1e-59 uspA T Universal stress protein family
PFAPIKCO_01800 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
PFAPIKCO_01801 1.1e-25
PFAPIKCO_01802 3.2e-200 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PFAPIKCO_01803 2.3e-109 puuD S peptidase C26
PFAPIKCO_01804 1.4e-83 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PFAPIKCO_01805 6.6e-151 lsa S ABC transporter
PFAPIKCO_01806 2.7e-148 mepA V MATE efflux family protein
PFAPIKCO_01807 8.1e-49 arbx M family 8
PFAPIKCO_01808 9.1e-31 L Helix-turn-helix domain
PFAPIKCO_01809 2.6e-89 L PFAM Integrase catalytic region
PFAPIKCO_01810 5.3e-31 cpsJ M Glycosyltransferase like family 2
PFAPIKCO_01811 1e-37 M Glycosyltransferase like family 2
PFAPIKCO_01812 2.8e-97 tnp2 L Transposase
PFAPIKCO_01813 1.2e-38 S glycosyl transferase family 2
PFAPIKCO_01814 2.1e-35 M family 8
PFAPIKCO_01815 2.6e-55 nss M transferase activity, transferring glycosyl groups
PFAPIKCO_01816 1.6e-40 nss M transferase activity, transferring glycosyl groups
PFAPIKCO_01818 1e-43 arbx M family 8
PFAPIKCO_01819 4.2e-66 nss M transferase activity, transferring glycosyl groups
PFAPIKCO_01820 7.1e-56 M lipopolysaccharide 3-alpha-galactosyltransferase activity
PFAPIKCO_01821 1.7e-110 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PFAPIKCO_01822 1.1e-34 yxaB 2.4.1.166 GT2 M Glycosyltransferase like family 2
PFAPIKCO_01823 1.2e-38 cpsJ S Glycosyltransferase like family 2
PFAPIKCO_01824 1.1e-39 cpsJ S Glycosyltransferase like family 2
PFAPIKCO_01825 1.4e-39 cpsJ S Glycosyltransferase like family 2
PFAPIKCO_01826 3.2e-153 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PFAPIKCO_01830 2.7e-247 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PFAPIKCO_01831 9.5e-31 asp3 S Accessory Sec system protein Asp3
PFAPIKCO_01832 7e-103 asp2 3.4.11.5 S Accessory Sec system protein Asp2
PFAPIKCO_01833 3.4e-84 asp1 S Accessory Sec system protein Asp1
PFAPIKCO_01834 2.7e-65 secY2 U SecY translocase
PFAPIKCO_01835 1.1e-137 S interspecies interaction between organisms
PFAPIKCO_01836 6.1e-207 G glycerol-3-phosphate transporter
PFAPIKCO_01837 9.8e-72 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PFAPIKCO_01838 1.3e-145 htrA 3.4.21.107 O serine protease
PFAPIKCO_01839 1.7e-116 vicX 3.1.26.11 S domain protein
PFAPIKCO_01840 6.8e-30 yyaQ S YjbR
PFAPIKCO_01841 2.1e-79 yycI S YycH protein
PFAPIKCO_01842 1.9e-101 yycH S YycH protein
PFAPIKCO_01843 9.6e-272 vicK 2.7.13.3 T Histidine kinase
PFAPIKCO_01844 9e-114 K response regulator
PFAPIKCO_01845 3.3e-09 bta 1.8.1.8 CO transport accessory protein
PFAPIKCO_01846 6.4e-93 comA V Papain-like cysteine protease AvrRpt2
PFAPIKCO_01847 1.4e-14 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PFAPIKCO_01848 1.9e-172 dltB M MBOAT, membrane-bound O-acyltransferase family
PFAPIKCO_01850 4.7e-106 yxeH S hydrolase
PFAPIKCO_01852 4.7e-95 S Domain of unknown function DUF87
PFAPIKCO_01854 4.1e-229 V ABC transporter transmembrane region
PFAPIKCO_01855 7.6e-215 XK27_09600 V ABC transporter, ATP-binding protein
PFAPIKCO_01856 7.1e-32 K Transcriptional regulator, MarR family
PFAPIKCO_01857 3.7e-172 S Putative peptidoglycan binding domain
PFAPIKCO_01859 2.8e-24 relB L RelB antitoxin
PFAPIKCO_01860 1.4e-61 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PFAPIKCO_01861 8.8e-140 gldA 1.1.1.6 C Iron-containing alcohol dehydrogenase
PFAPIKCO_01862 1.7e-178 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PFAPIKCO_01863 1.9e-108 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PFAPIKCO_01864 6e-223 pepF E Oligopeptidase F
PFAPIKCO_01865 3.7e-96 yicL EG EamA-like transporter family
PFAPIKCO_01866 3.1e-69 2.3.1.178 J Acetyltransferase (GNAT) domain
PFAPIKCO_01867 1.6e-167 yjjP S Putative threonine/serine exporter
PFAPIKCO_01868 4.8e-109 glcU U sugar transport
PFAPIKCO_01869 5.9e-15 K regulatory protein TetR
PFAPIKCO_01870 9.3e-151 mdtG EGP Major facilitator Superfamily
PFAPIKCO_01871 2.3e-90 L PFAM Integrase catalytic region
PFAPIKCO_01872 3.5e-30 L Helix-turn-helix domain
PFAPIKCO_01873 9.1e-106 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PFAPIKCO_01874 5.5e-223 yxbA 6.3.1.12 S ATP-grasp enzyme
PFAPIKCO_01875 1.6e-229 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PFAPIKCO_01876 3.6e-17 yneR
PFAPIKCO_01877 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_01878 7.7e-245 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PFAPIKCO_01879 9.2e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PFAPIKCO_01880 4.1e-21 yiiE S Protein of unknown function (DUF1211)
PFAPIKCO_01881 0.0 asnB 6.3.5.4 E Asparagine synthase
PFAPIKCO_01882 1.1e-64 D peptidase
PFAPIKCO_01883 3.3e-117 S Glycosyl transferase family 2
PFAPIKCO_01884 1.4e-108 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
PFAPIKCO_01885 1.6e-97 tnp2 L Transposase
PFAPIKCO_01886 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PFAPIKCO_01887 8.7e-64 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PFAPIKCO_01888 4.8e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
PFAPIKCO_01889 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PFAPIKCO_01890 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PFAPIKCO_01891 8.4e-154 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PFAPIKCO_01892 9e-20 yaaA S S4 domain protein YaaA
PFAPIKCO_01893 7.4e-98 tnp2 L Transposase
PFAPIKCO_01894 1.9e-158 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PFAPIKCO_01897 1.2e-99 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PFAPIKCO_01898 1.1e-78 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PFAPIKCO_01899 5e-30
PFAPIKCO_01900 6.4e-33 sip L Belongs to the 'phage' integrase family
PFAPIKCO_01901 6.5e-07
PFAPIKCO_01904 1.6e-28 M CHAP domain
PFAPIKCO_01906 8.5e-191 U type IV secretory pathway VirB4
PFAPIKCO_01907 2.7e-27
PFAPIKCO_01909 1.2e-76
PFAPIKCO_01910 1.1e-218 U TraM recognition site of TraD and TraG
PFAPIKCO_01914 2e-149 clpB O Belongs to the ClpA ClpB family
PFAPIKCO_01916 4.9e-265 L PFAM Integrase catalytic region
PFAPIKCO_01918 1.9e-165 topA2 5.99.1.2 G Topoisomerase IA
PFAPIKCO_01919 6.8e-42 L Protein of unknown function (DUF3991)
PFAPIKCO_01920 3.8e-68
PFAPIKCO_01922 1.3e-33 3.1.21.3 V type I restriction modification DNA specificity domain
PFAPIKCO_01923 2.7e-22 S PIN domain
PFAPIKCO_01924 2.6e-11 D Antitoxin component of a toxin-antitoxin (TA) module
PFAPIKCO_01926 1.1e-86 pac DM Glucan-binding protein C
PFAPIKCO_01927 3.4e-11 sdrF M domain protein
PFAPIKCO_01929 6.6e-92 L Transposase, IS605 OrfB family
PFAPIKCO_01930 1e-54 tlpA2 L Transposase IS200 like
PFAPIKCO_01931 1.1e-26 S Fic/DOC family
PFAPIKCO_01935 1.8e-61 ruvB 3.6.4.12 L four-way junction helicase activity
PFAPIKCO_01940 1.8e-18
PFAPIKCO_01941 1.2e-30 S Protein of unknown function (DUF3800)
PFAPIKCO_01943 6.1e-07
PFAPIKCO_01948 2.2e-20 S Replication initiator protein A (RepA) N-terminus
PFAPIKCO_01949 4.9e-265 L PFAM Integrase catalytic region
PFAPIKCO_01951 5.3e-09 S Arc-like DNA binding domain
PFAPIKCO_01953 3.5e-12 K Helix-turn-helix XRE-family like proteins
PFAPIKCO_01954 3.2e-217 tnp4 L Psort location Cytoplasmic, score 8.96
PFAPIKCO_01955 1.1e-15
PFAPIKCO_01956 3.6e-112 rssA S Phospholipase, patatin family
PFAPIKCO_01957 7.4e-98 tnp2 L Transposase
PFAPIKCO_01958 7.6e-136 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PFAPIKCO_01959 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
PFAPIKCO_01960 2.5e-45 S VIT family
PFAPIKCO_01961 4.2e-240 sufB O assembly protein SufB
PFAPIKCO_01962 1.9e-40 nifU C SUF system FeS assembly protein, NifU family
PFAPIKCO_01963 4.1e-146 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PFAPIKCO_01964 6.6e-144 sufD O FeS assembly protein SufD
PFAPIKCO_01965 6.2e-116 sufC O FeS assembly ATPase SufC
PFAPIKCO_01966 9.2e-192 E ABC transporter, substratebinding protein
PFAPIKCO_01968 3.7e-26 K Helix-turn-helix XRE-family like proteins
PFAPIKCO_01969 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PFAPIKCO_01970 3.8e-55 3.1.21.3 V type I restriction modification DNA specificity domain
PFAPIKCO_01971 2.5e-127 xerC L Belongs to the 'phage' integrase family
PFAPIKCO_01972 5.4e-42 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction
PFAPIKCO_01973 1.6e-46 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
PFAPIKCO_01974 3.5e-248 2.1.1.72 V type I restriction-modification system
PFAPIKCO_01975 1.3e-58 hsdM 2.1.1.72 V HsdM N-terminal domain
PFAPIKCO_01976 3.8e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
PFAPIKCO_01977 3.3e-136 pfoS S Phosphotransferase system, EIIC
PFAPIKCO_01978 7.2e-117 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PFAPIKCO_01979 2.5e-65 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
PFAPIKCO_01980 2.4e-36 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PFAPIKCO_01981 1.2e-135 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
PFAPIKCO_01982 2.8e-83 srlA G PTS system enzyme II sorbitol-specific factor
PFAPIKCO_01983 2.9e-42 gutM K Glucitol operon activator protein (GutM)
PFAPIKCO_01984 2.2e-103 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
PFAPIKCO_01985 5.2e-110 IQ NAD dependent epimerase/dehydratase family
PFAPIKCO_01986 3.3e-17 yuaG 3.4.21.72 M by MetaGeneAnnotator
PFAPIKCO_01987 1.6e-30 M Phage tail tape measure protein TP901
PFAPIKCO_01990 4.3e-07
PFAPIKCO_01995 2.4e-29 S Phage minor capsid protein 2
PFAPIKCO_01996 7.2e-100 fabK 1.3.1.9 S Nitronate monooxygenase
PFAPIKCO_01997 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PFAPIKCO_01998 2.8e-266 fbp 3.1.3.11 G phosphatase activity
PFAPIKCO_01999 1.7e-71 xerD L Phage integrase, N-terminal SAM-like domain
PFAPIKCO_02005 2.3e-57 K LytTr DNA-binding domain
PFAPIKCO_02006 7.2e-28 2.7.13.3 T GHKL domain
PFAPIKCO_02007 4.4e-13 2.7.13.3 T GHKL domain
PFAPIKCO_02012 7.3e-13
PFAPIKCO_02013 3.2e-08
PFAPIKCO_02015 2.7e-88 S Haloacid dehalogenase-like hydrolase
PFAPIKCO_02016 1.8e-14
PFAPIKCO_02018 1.1e-159 L transposase, IS605 OrfB family
PFAPIKCO_02019 9.5e-58 tlpA2 L Transposase IS200 like
PFAPIKCO_02020 7.2e-188 mtnE 2.6.1.83 E Aminotransferase
PFAPIKCO_02021 2.2e-81 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PFAPIKCO_02022 3.4e-67 S Protein of unknown function (DUF1440)
PFAPIKCO_02023 7.7e-41 S Iron-sulfur cluster assembly protein
PFAPIKCO_02024 5.5e-113 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PFAPIKCO_02025 4.5e-75 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PFAPIKCO_02026 7.8e-208 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PFAPIKCO_02027 7.9e-155 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PFAPIKCO_02028 4.7e-65 G Xylose isomerase domain protein TIM barrel
PFAPIKCO_02029 1.1e-53 ndk 2.7.4.6 F Belongs to the NDK family
PFAPIKCO_02030 6.5e-90 nanK GK ROK family
PFAPIKCO_02031 1.3e-127 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
PFAPIKCO_02032 4.7e-91 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PFAPIKCO_02033 1.9e-75 K Helix-turn-helix domain, rpiR family
PFAPIKCO_02034 1.2e-61 yphA GM NAD dependent epimerase/dehydratase family
PFAPIKCO_02035 1.7e-218 yjeM E Amino Acid
PFAPIKCO_02036 5.3e-96 tnp2 L Transposase
PFAPIKCO_02038 1.2e-31 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PFAPIKCO_02039 1.9e-179 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PFAPIKCO_02040 3.9e-48 fucU 5.1.3.29 G RbsD / FucU transport protein family
PFAPIKCO_02041 3.5e-180 xylB 2.7.1.17 GH19 EGP Major facilitator Superfamily
PFAPIKCO_02042 2.3e-132 rhaB 2.7.1.5, 2.7.1.51 G FGGY family of carbohydrate kinases, N-terminal domain
PFAPIKCO_02043 2.6e-295 fucI 5.3.1.25, 5.3.1.3 G Converts the aldose L-fucose into the corresponding ketose L-fuculose
PFAPIKCO_02044 2e-55 fcsR K DeoR C terminal sensor domain
PFAPIKCO_02045 2.5e-101 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
PFAPIKCO_02046 3.2e-08 cps2D 5.1.3.2 M RmlD substrate binding domain
PFAPIKCO_02047 2.1e-40 wecD M Acetyltransferase (GNAT) family
PFAPIKCO_02049 2.8e-26 ybl78 L Conserved phage C-terminus (Phg_2220_C)
PFAPIKCO_02050 6.6e-41 S Protein of unknown function (DUF1211)
PFAPIKCO_02051 5e-70 L Transposase DDE domain group 1
PFAPIKCO_02053 4.3e-235 tetP J elongation factor G
PFAPIKCO_02054 1.8e-53 L Integrase core domain
PFAPIKCO_02055 4.3e-19 L HTH-like domain
PFAPIKCO_02056 1.1e-19 L Helix-turn-helix domain
PFAPIKCO_02060 2.8e-41 S protein disulfide oxidoreductase activity
PFAPIKCO_02061 7.4e-10
PFAPIKCO_02062 3.9e-48 polC 2.7.7.7 L DNA polymerase III
PFAPIKCO_02063 3.3e-28 XK27_10050 K Peptidase S24-like
PFAPIKCO_02065 3.8e-75 Z012_01130 S Fic/DOC family
PFAPIKCO_02066 1.2e-24 polC_1 2.7.7.7 L 3' exoribonuclease, RNase T-like
PFAPIKCO_02067 2.4e-10
PFAPIKCO_02068 1.7e-19
PFAPIKCO_02069 2.6e-48 mloB K Transcriptional regulator
PFAPIKCO_02071 4.7e-108 L Initiator Replication protein
PFAPIKCO_02072 1.1e-37 S Replication initiator protein A (RepA) N-terminus
PFAPIKCO_02073 1.7e-100 L Probable transposase
PFAPIKCO_02075 1.9e-91 D CobQ CobB MinD ParA nucleotide binding domain protein
PFAPIKCO_02078 0.0 pepN 3.4.11.2 E aminopeptidase
PFAPIKCO_02079 2.7e-44 2.7.13.3 T protein histidine kinase activity
PFAPIKCO_02080 1.3e-35 agrA KT Response regulator of the LytR AlgR family
PFAPIKCO_02081 9.5e-21 M domain protein
PFAPIKCO_02082 5.9e-109 XK27_09655 S Virulence protein RhuM family
PFAPIKCO_02083 3.3e-156 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PFAPIKCO_02084 5.1e-124 yvgN C Aldo keto reductase
PFAPIKCO_02085 6.5e-70 K DeoR C terminal sensor domain
PFAPIKCO_02086 1.1e-46 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PFAPIKCO_02087 6.9e-42 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PFAPIKCO_02088 3.6e-216 pts36C G PTS system sugar-specific permease component
PFAPIKCO_02090 1.5e-103 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
PFAPIKCO_02092 6e-57 S COG NOG19168 non supervised orthologous group
PFAPIKCO_02093 1.8e-177 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PFAPIKCO_02095 4.9e-50 S Membrane
PFAPIKCO_02096 1.4e-75 rhaR K helix_turn_helix, arabinose operon control protein
PFAPIKCO_02097 2.6e-188 iolF EGP Major facilitator Superfamily
PFAPIKCO_02098 2.2e-215 rhaB 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PFAPIKCO_02099 4e-40 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
PFAPIKCO_02100 2.8e-219 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
PFAPIKCO_02101 6.9e-110 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
PFAPIKCO_02102 4.9e-190 XK27_11280 S Psort location CytoplasmicMembrane, score
PFAPIKCO_02104 2.2e-104 L Belongs to the 'phage' integrase family
PFAPIKCO_02105 3.4e-23 3.1.21.3 V Type I restriction modification DNA specificity domain
PFAPIKCO_02106 2.1e-58 hsdM 2.1.1.72 V type I restriction-modification system
PFAPIKCO_02108 2.5e-227 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
PFAPIKCO_02109 4.7e-248 sthIM 2.1.1.72 L DNA methylase
PFAPIKCO_02110 2.8e-205 sthIM 2.1.1.72 L DNA methylase
PFAPIKCO_02111 2.6e-259 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
PFAPIKCO_02112 4.9e-18
PFAPIKCO_02113 3.4e-24
PFAPIKCO_02116 2.1e-116 queH 1.17.99.6, 3.1.26.4 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PFAPIKCO_02117 1.2e-56 racA K Domain of unknown function (DUF1836)
PFAPIKCO_02118 1.8e-07 yitS S EDD domain protein, DegV family
PFAPIKCO_02119 3.2e-65 yitS S EDD domain protein, DegV family
PFAPIKCO_02120 6.4e-36 S Enterocin A Immunity
PFAPIKCO_02121 1e-36 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PFAPIKCO_02122 0.0 O Belongs to the peptidase S8 family
PFAPIKCO_02123 2.1e-26 S protein encoded in hypervariable junctions of pilus gene clusters
PFAPIKCO_02124 9e-102 qmcA O prohibitin homologues
PFAPIKCO_02125 1.8e-11 S YjcQ protein
PFAPIKCO_02126 7.5e-83 L COG1961 Site-specific recombinases, DNA invertase Pin homologs
PFAPIKCO_02127 4.7e-70 S Recombinase
PFAPIKCO_02128 7.9e-296 L Recombinase
PFAPIKCO_02129 1.6e-32 K Cro/C1-type HTH DNA-binding domain
PFAPIKCO_02130 3.1e-164 L Nucleotidyltransferase domain
PFAPIKCO_02131 6.8e-141 Q Protein of unknown function (DUF1698)
PFAPIKCO_02132 3.8e-167 aadK G adenylyltransferase
PFAPIKCO_02134 4.2e-56 apt 2.4.2.7 F purine ribonucleoside salvage
PFAPIKCO_02135 9e-220 tnp4 L L COG3328 Transposase and inactivated derivatives
PFAPIKCO_02136 1.7e-284 aacA-aphD 2.3.1.57, 2.3.1.82, 2.7.1.190 F Involved in resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region. The C-terminal region is a kinase that phosphorylates several 4,6-disubstituted aminoglycosides
PFAPIKCO_02137 3.4e-73 K FR47-like protein
PFAPIKCO_02138 9e-220 tnp4 L L COG3328 Transposase and inactivated derivatives
PFAPIKCO_02139 1.3e-251 L Transposase DDE domain group 1
PFAPIKCO_02140 2.8e-54 1.14.12.17 C Oxidoreductase NAD-binding domain
PFAPIKCO_02141 4.3e-58 tlpA2 L Transposase IS200 like
PFAPIKCO_02142 1.5e-159 L transposase, IS605 OrfB family
PFAPIKCO_02143 8.6e-125 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PFAPIKCO_02144 1.5e-30 L hmm pf00665
PFAPIKCO_02145 2.9e-54 tlpA2 L Transposase IS200 like
PFAPIKCO_02146 8.6e-92 L Transposase, IS605 OrfB family
PFAPIKCO_02147 1.6e-56 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PFAPIKCO_02148 1.1e-142 xerS L Phage integrase family
PFAPIKCO_02152 5.2e-104 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PFAPIKCO_02153 9.6e-72 ptp3 3.1.3.48 T Tyrosine phosphatase family
PFAPIKCO_02154 5.8e-77 desR K helix_turn_helix, Lux Regulon
PFAPIKCO_02155 1.3e-52 desK 2.7.13.3 T Histidine kinase
PFAPIKCO_02156 1.6e-52 yvfS V ABC-2 type transporter
PFAPIKCO_02157 3.6e-80 yvfR V ABC transporter
PFAPIKCO_02165 8.7e-119 tetP J Elongation factor
PFAPIKCO_02166 1.4e-35 dam 2.1.1.72 L Site-specific DNA-methyltransferase (Adenine-specific)
PFAPIKCO_02167 2.6e-34 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PFAPIKCO_02168 1.9e-70 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PFAPIKCO_02169 2.8e-74 S ABC-2 family transporter protein
PFAPIKCO_02170 1.3e-168 bcrA V ABC transporter
PFAPIKCO_02171 1.1e-104 K Psort location CytoplasmicMembrane, score
PFAPIKCO_02172 1.8e-48 L Resolvase, N terminal domain
PFAPIKCO_02175 5.7e-52 L Protein involved in initiation of plasmid replication
PFAPIKCO_02176 3.7e-216 L Probable transposase
PFAPIKCO_02180 1.4e-178 pre D Plasmid recombination enzyme
PFAPIKCO_02181 4.3e-237 tetL EGP Major Facilitator Superfamily
PFAPIKCO_02182 4.2e-186 tetP J Elongation factor G, domain IV

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)