ORF_ID e_value Gene_name EC_number CAZy COGs Description
ICDKHGKO_00001 8.9e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICDKHGKO_00002 8e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ICDKHGKO_00003 2.4e-33 yaaA S S4 domain
ICDKHGKO_00004 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICDKHGKO_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
ICDKHGKO_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICDKHGKO_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ICDKHGKO_00008 2.2e-38 S COG NOG14552 non supervised orthologous group
ICDKHGKO_00011 1.5e-175 yaaC S YaaC-like Protein
ICDKHGKO_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
ICDKHGKO_00013 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ICDKHGKO_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ICDKHGKO_00015 4.7e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ICDKHGKO_00016 1.1e-202 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICDKHGKO_00017 2.3e-196 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ICDKHGKO_00018 1.3e-09
ICDKHGKO_00019 6.6e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
ICDKHGKO_00020 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
ICDKHGKO_00021 3.9e-208 yaaH M Glycoside Hydrolase Family
ICDKHGKO_00022 6.6e-96 yaaI Q COG1335 Amidases related to nicotinamidase
ICDKHGKO_00023 9.5e-83 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ICDKHGKO_00024 2.3e-311 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICDKHGKO_00025 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ICDKHGKO_00026 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ICDKHGKO_00027 3.6e-32 yaaL S Protein of unknown function (DUF2508)
ICDKHGKO_00028 4.8e-36 bofA S Sigma-K factor-processing regulatory protein BofA
ICDKHGKO_00029 2.2e-38 S COG NOG14552 non supervised orthologous group
ICDKHGKO_00032 7.9e-28 csfB S Inhibitor of sigma-G Gin
ICDKHGKO_00033 1.1e-99 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
ICDKHGKO_00034 2.6e-176 yaaN P Belongs to the TelA family
ICDKHGKO_00035 1.9e-256 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
ICDKHGKO_00036 7.8e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICDKHGKO_00037 2.9e-54 yaaQ S protein conserved in bacteria
ICDKHGKO_00038 3.8e-70 yaaR S protein conserved in bacteria
ICDKHGKO_00039 8.5e-179 holB 2.7.7.7 L DNA polymerase III
ICDKHGKO_00040 1.1e-144 yaaT S stage 0 sporulation protein
ICDKHGKO_00041 5e-36 yabA L Involved in initiation control of chromosome replication
ICDKHGKO_00042 1.6e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
ICDKHGKO_00043 5.2e-47 yazA L endonuclease containing a URI domain
ICDKHGKO_00044 2.8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ICDKHGKO_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
ICDKHGKO_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICDKHGKO_00047 2.2e-142 tatD L hydrolase, TatD
ICDKHGKO_00048 4e-216 rpfB GH23 T protein conserved in bacteria
ICDKHGKO_00049 2.3e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ICDKHGKO_00050 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ICDKHGKO_00051 8.2e-125 yabG S peptidase
ICDKHGKO_00052 7.8e-39 veg S protein conserved in bacteria
ICDKHGKO_00053 2.9e-27 sspF S DNA topological change
ICDKHGKO_00054 7.8e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICDKHGKO_00055 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
ICDKHGKO_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
ICDKHGKO_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
ICDKHGKO_00058 1.7e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICDKHGKO_00059 2.7e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICDKHGKO_00060 2.8e-103 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ICDKHGKO_00061 1.2e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ICDKHGKO_00062 6.9e-39 yabK S Peptide ABC transporter permease
ICDKHGKO_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICDKHGKO_00064 2.6e-89 spoVT K stage V sporulation protein
ICDKHGKO_00065 5.8e-270 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICDKHGKO_00066 7e-270 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
ICDKHGKO_00067 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
ICDKHGKO_00068 1.9e-49 yabP S Sporulation protein YabP
ICDKHGKO_00069 2.5e-99 yabQ S spore cortex biosynthesis protein
ICDKHGKO_00070 9.2e-57 divIC D Septum formation initiator
ICDKHGKO_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
ICDKHGKO_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
ICDKHGKO_00075 1.2e-121 yabS S protein containing a von Willebrand factor type A (vWA) domain
ICDKHGKO_00076 9.2e-181 KLT serine threonine protein kinase
ICDKHGKO_00077 2.1e-263 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ICDKHGKO_00078 2.5e-92 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ICDKHGKO_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICDKHGKO_00080 2.4e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ICDKHGKO_00081 1.2e-160 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICDKHGKO_00082 5.7e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
ICDKHGKO_00083 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ICDKHGKO_00084 6.1e-263 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICDKHGKO_00085 5.7e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
ICDKHGKO_00086 1.6e-149 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
ICDKHGKO_00087 9.1e-153 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ICDKHGKO_00088 2.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICDKHGKO_00089 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ICDKHGKO_00090 7.1e-28 yazB K transcriptional
ICDKHGKO_00091 1.6e-180 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICDKHGKO_00092 1.6e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
ICDKHGKO_00093 2.2e-38 S COG NOG14552 non supervised orthologous group
ICDKHGKO_00095 1.3e-07
ICDKHGKO_00098 2e-08
ICDKHGKO_00103 2.2e-38 S COG NOG14552 non supervised orthologous group
ICDKHGKO_00104 7.5e-77 ctsR K Belongs to the CtsR family
ICDKHGKO_00105 1.1e-60 mcsA 2.7.14.1 S protein with conserved CXXC pairs
ICDKHGKO_00106 2.7e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
ICDKHGKO_00107 0.0 clpC O Belongs to the ClpA ClpB family
ICDKHGKO_00108 3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ICDKHGKO_00109 2.7e-194 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ICDKHGKO_00110 5.2e-185 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
ICDKHGKO_00111 8.8e-122 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
ICDKHGKO_00112 3.5e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
ICDKHGKO_00113 4.2e-275 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICDKHGKO_00114 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
ICDKHGKO_00115 1.1e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICDKHGKO_00116 1.7e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ICDKHGKO_00117 1.8e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICDKHGKO_00118 1.8e-87 yacP S RNA-binding protein containing a PIN domain
ICDKHGKO_00119 4.4e-115 sigH K Belongs to the sigma-70 factor family
ICDKHGKO_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ICDKHGKO_00121 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
ICDKHGKO_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICDKHGKO_00123 2.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ICDKHGKO_00124 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ICDKHGKO_00125 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ICDKHGKO_00126 4.8e-108 rsmC 2.1.1.172 J Methyltransferase
ICDKHGKO_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICDKHGKO_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICDKHGKO_00129 2.7e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
ICDKHGKO_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICDKHGKO_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ICDKHGKO_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICDKHGKO_00133 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICDKHGKO_00134 2.6e-172 ybaC 3.4.11.5 S Alpha/beta hydrolase family
ICDKHGKO_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
ICDKHGKO_00136 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICDKHGKO_00137 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
ICDKHGKO_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ICDKHGKO_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICDKHGKO_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ICDKHGKO_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICDKHGKO_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICDKHGKO_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICDKHGKO_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
ICDKHGKO_00145 1.8e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICDKHGKO_00146 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICDKHGKO_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ICDKHGKO_00148 3.9e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICDKHGKO_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICDKHGKO_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ICDKHGKO_00151 1.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICDKHGKO_00152 2.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICDKHGKO_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ICDKHGKO_00154 1.9e-23 rpmD J Ribosomal protein L30
ICDKHGKO_00155 4.1e-72 rplO J binds to the 23S rRNA
ICDKHGKO_00156 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ICDKHGKO_00157 9.8e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ICDKHGKO_00158 2.6e-140 map 3.4.11.18 E Methionine aminopeptidase
ICDKHGKO_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ICDKHGKO_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
ICDKHGKO_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ICDKHGKO_00162 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ICDKHGKO_00163 5.3e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICDKHGKO_00164 4.7e-58 rplQ J Ribosomal protein L17
ICDKHGKO_00165 1.4e-153 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICDKHGKO_00166 1.2e-144 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICDKHGKO_00167 1.9e-136 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ICDKHGKO_00168 5.9e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ICDKHGKO_00169 7.1e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICDKHGKO_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
ICDKHGKO_00171 2.7e-140 ybaJ Q Methyltransferase domain
ICDKHGKO_00172 5.3e-15 ybaJ Q Methyltransferase domain
ICDKHGKO_00173 3.6e-76 ybaK S Protein of unknown function (DUF2521)
ICDKHGKO_00174 2.4e-130 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ICDKHGKO_00175 2.5e-192 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
ICDKHGKO_00176 1.7e-75 gerD
ICDKHGKO_00177 1.7e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
ICDKHGKO_00178 1.2e-127 pdaB 3.5.1.104 G Polysaccharide deacetylase
ICDKHGKO_00179 2.2e-38 S COG NOG14552 non supervised orthologous group
ICDKHGKO_00182 1.6e-08
ICDKHGKO_00185 2.2e-38 S COG NOG14552 non supervised orthologous group
ICDKHGKO_00186 2.2e-213 glcP G Major Facilitator Superfamily
ICDKHGKO_00187 1e-245 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICDKHGKO_00188 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
ICDKHGKO_00189 2.9e-201 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
ICDKHGKO_00190 1.1e-222 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
ICDKHGKO_00191 3.2e-170 ybaS 1.1.1.58 S Na -dependent transporter
ICDKHGKO_00192 2.2e-102 ybbA S Putative esterase
ICDKHGKO_00193 7e-176 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICDKHGKO_00194 1.5e-175 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICDKHGKO_00195 4.5e-169 feuA P Iron-uptake system-binding protein
ICDKHGKO_00196 1.3e-290 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
ICDKHGKO_00197 7.8e-230 ybbC 3.2.1.52 S protein conserved in bacteria
ICDKHGKO_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
ICDKHGKO_00199 1.5e-236 yfeW 3.4.16.4 V Belongs to the UPF0214 family
ICDKHGKO_00200 1.9e-229 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ICDKHGKO_00201 8.3e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ICDKHGKO_00202 4.9e-59 ybbJ J acetyltransferase
ICDKHGKO_00203 1.2e-74 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
ICDKHGKO_00207 1.5e-07
ICDKHGKO_00209 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
ICDKHGKO_00210 5.2e-113 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
ICDKHGKO_00211 1.1e-144 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ICDKHGKO_00212 1.9e-216 ybbR S protein conserved in bacteria
ICDKHGKO_00213 2.3e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICDKHGKO_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ICDKHGKO_00215 9.2e-36
ICDKHGKO_00216 1.7e-197 O growth
ICDKHGKO_00217 1.1e-52 S ABC-2 family transporter protein
ICDKHGKO_00218 4.3e-100 ybdN
ICDKHGKO_00219 2.7e-131 ybdO S Domain of unknown function (DUF4885)
ICDKHGKO_00220 4.4e-160 dkgB S Aldo/keto reductase family
ICDKHGKO_00221 1.5e-92 yxaC M effector of murein hydrolase
ICDKHGKO_00222 2.2e-50 S LrgA family
ICDKHGKO_00223 2.3e-67 yxaD K helix_turn_helix multiple antibiotic resistance protein
ICDKHGKO_00224 2.7e-255 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
ICDKHGKO_00225 3.6e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
ICDKHGKO_00226 4.8e-178 T COG4585 Signal transduction histidine kinase
ICDKHGKO_00227 3e-100 KT LuxR family transcriptional regulator
ICDKHGKO_00228 6.4e-160 V COG1131 ABC-type multidrug transport system, ATPase component
ICDKHGKO_00229 8.4e-189 V COG0842 ABC-type multidrug transport system, permease component
ICDKHGKO_00230 1.8e-180 V ABC-2 family transporter protein
ICDKHGKO_00231 9.2e-23
ICDKHGKO_00232 1.4e-72 S Domain of unknown function (DUF4879)
ICDKHGKO_00233 1.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
ICDKHGKO_00234 2.5e-100 yqeB
ICDKHGKO_00235 2.3e-38 ybyB
ICDKHGKO_00236 1.2e-275 ybeC E amino acid
ICDKHGKO_00237 1.2e-15 S Protein of unknown function (DUF2651)
ICDKHGKO_00238 2e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ICDKHGKO_00239 1.6e-257 glpT G -transporter
ICDKHGKO_00240 2.7e-17 S Protein of unknown function (DUF2651)
ICDKHGKO_00241 9.5e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
ICDKHGKO_00243 3.9e-81 K Helix-turn-helix XRE-family like proteins
ICDKHGKO_00244 7e-187 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
ICDKHGKO_00245 1.7e-207 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ICDKHGKO_00246 1.9e-92 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICDKHGKO_00247 5.1e-84 ybfM S SNARE associated Golgi protein
ICDKHGKO_00248 9e-150 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
ICDKHGKO_00249 2.8e-39 ybfN
ICDKHGKO_00250 2.6e-188 yceA S Belongs to the UPF0176 family
ICDKHGKO_00251 6.3e-211 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICDKHGKO_00252 2.3e-193 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
ICDKHGKO_00253 6.5e-238 mmuP E amino acid
ICDKHGKO_00254 7.7e-177 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
ICDKHGKO_00255 1.9e-251 agcS E Sodium alanine symporter
ICDKHGKO_00256 8.3e-72 glsA 3.5.1.2 E Belongs to the glutaminase family
ICDKHGKO_00257 2.6e-34 glsA 3.5.1.2 E Belongs to the glutaminase family
ICDKHGKO_00258 4.6e-201 phoQ 2.7.13.3 T Histidine kinase
ICDKHGKO_00259 1.7e-155 glnL T Regulator
ICDKHGKO_00260 3.5e-126 ycbJ S Macrolide 2'-phosphotransferase
ICDKHGKO_00261 4.5e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
ICDKHGKO_00262 1.3e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICDKHGKO_00263 3.5e-91 ydfN C nitroreductase
ICDKHGKO_00264 2.5e-180 ydfO E COG0346 Lactoylglutathione lyase and related lyases
ICDKHGKO_00265 7.5e-62 mhqP S DoxX
ICDKHGKO_00266 3.5e-55 traF CO Thioredoxin
ICDKHGKO_00267 7.4e-62 ycbP S Protein of unknown function (DUF2512)
ICDKHGKO_00268 4.8e-78 sleB 3.5.1.28 M Cell wall
ICDKHGKO_00269 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
ICDKHGKO_00270 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
ICDKHGKO_00271 9e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ICDKHGKO_00272 5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ICDKHGKO_00273 2.7e-189 ycbU E Selenocysteine lyase
ICDKHGKO_00274 1.4e-235 lmrB EGP the major facilitator superfamily
ICDKHGKO_00275 3.6e-97 yxaF K Transcriptional regulator
ICDKHGKO_00276 7.5e-46 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
ICDKHGKO_00277 6.4e-16 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
ICDKHGKO_00278 8e-191 yccF K DNA-templated transcriptional preinitiation complex assembly
ICDKHGKO_00279 1e-165 yccK C Aldo keto reductase
ICDKHGKO_00280 2.7e-164 ycdA S Domain of unknown function (DUF5105)
ICDKHGKO_00281 2.2e-236 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
ICDKHGKO_00282 1e-251 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
ICDKHGKO_00283 1.8e-87 cwlK M D-alanyl-D-alanine carboxypeptidase
ICDKHGKO_00284 2e-171 S response regulator aspartate phosphatase
ICDKHGKO_00285 2e-135 IQ Enoyl-(Acyl carrier protein) reductase
ICDKHGKO_00286 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
ICDKHGKO_00287 1.6e-48 S Domain of unknown function (DUF4188)
ICDKHGKO_00288 1.5e-47 padR K Virulence activator alpha C-term
ICDKHGKO_00289 1.1e-162 adcA P Belongs to the bacterial solute-binding protein 9 family
ICDKHGKO_00290 1.6e-131 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
ICDKHGKO_00291 2.2e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
ICDKHGKO_00292 1.4e-181 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICDKHGKO_00293 6.2e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
ICDKHGKO_00294 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
ICDKHGKO_00295 3.3e-106 yceE T proteins involved in stress response, homologs of TerZ and
ICDKHGKO_00296 1.7e-137 terC P Protein of unknown function (DUF475)
ICDKHGKO_00297 2.7e-307 yceG S Putative component of 'biosynthetic module'
ICDKHGKO_00298 4.3e-192 yceH P Belongs to the TelA family
ICDKHGKO_00299 1.8e-207 naiP P Uncharacterised MFS-type transporter YbfB
ICDKHGKO_00301 1.4e-226 proV 3.6.3.32 E glycine betaine
ICDKHGKO_00302 6.9e-137 opuAB P glycine betaine
ICDKHGKO_00303 4.2e-161 opuAC E glycine betaine
ICDKHGKO_00304 1e-204 amhX S amidohydrolase
ICDKHGKO_00305 9e-164 ycgA S Membrane
ICDKHGKO_00306 1.6e-20 ycgA S Membrane
ICDKHGKO_00307 5.2e-42 ycgB
ICDKHGKO_00308 2.3e-12 S RDD family
ICDKHGKO_00309 2.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ICDKHGKO_00310 3.2e-257 mdr EGP Major facilitator Superfamily
ICDKHGKO_00311 2.9e-73 emrR K helix_turn_helix multiple antibiotic resistance protein
ICDKHGKO_00313 4.5e-42 ycgF E Lysine exporter protein LysE YggA
ICDKHGKO_00314 1.5e-58 ycgF E Lysine exporter protein LysE YggA
ICDKHGKO_00315 3.1e-144 yqcI S YqcI/YcgG family
ICDKHGKO_00316 4.5e-239 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
ICDKHGKO_00317 4.2e-112 ycgI S Domain of unknown function (DUF1989)
ICDKHGKO_00318 3.2e-147 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ICDKHGKO_00319 3.8e-129 4.2.1.118 G Xylose isomerase-like TIM barrel
ICDKHGKO_00320 4.1e-221 G COG0477 Permeases of the major facilitator superfamily
ICDKHGKO_00321 3.3e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ICDKHGKO_00322 4e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
ICDKHGKO_00323 7.6e-138 ycgL S Predicted nucleotidyltransferase
ICDKHGKO_00324 6.2e-168 ycgM E Proline dehydrogenase
ICDKHGKO_00325 2.9e-290 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
ICDKHGKO_00326 3.2e-243 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICDKHGKO_00327 3.7e-224 ycgP QT COG2508 Regulator of polyketide synthase expression
ICDKHGKO_00328 2.4e-184 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
ICDKHGKO_00329 9e-262 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
ICDKHGKO_00330 1.5e-55 nirD 1.7.1.15 P Nitrite reductase
ICDKHGKO_00331 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICDKHGKO_00332 2.7e-39 nasA P COG2223 Nitrate nitrite transporter
ICDKHGKO_00333 3.4e-222 yciC S GTPases (G3E family)
ICDKHGKO_00334 1.7e-218 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
ICDKHGKO_00335 5.2e-72 yckC S membrane
ICDKHGKO_00336 3.5e-49 S Protein of unknown function (DUF2680)
ICDKHGKO_00337 2.3e-286 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ICDKHGKO_00338 4.3e-65 nin S Competence protein J (ComJ)
ICDKHGKO_00339 4.2e-77 nucA M Deoxyribonuclease NucA/NucB
ICDKHGKO_00340 1.3e-91 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
ICDKHGKO_00341 1.2e-101 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
ICDKHGKO_00342 1.1e-62 hxlR K transcriptional
ICDKHGKO_00343 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICDKHGKO_00344 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICDKHGKO_00345 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
ICDKHGKO_00346 2.7e-137 srfAD Q thioesterase
ICDKHGKO_00347 8.8e-248 bamJ E Aminotransferase class I and II
ICDKHGKO_00348 5.5e-121 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
ICDKHGKO_00349 8e-106 yczE S membrane
ICDKHGKO_00350 1.7e-131 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ICDKHGKO_00351 1e-117 tcyB P COG0765 ABC-type amino acid transport system, permease component
ICDKHGKO_00352 6.7e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
ICDKHGKO_00353 1.6e-152 bsdA K LysR substrate binding domain
ICDKHGKO_00354 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
ICDKHGKO_00355 1.5e-280 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
ICDKHGKO_00356 9.2e-36 bsdD 4.1.1.61 S response to toxic substance
ICDKHGKO_00357 6.6e-73 yclD
ICDKHGKO_00358 6.8e-265 dtpT E amino acid peptide transporter
ICDKHGKO_00359 7.8e-260 yclG M Pectate lyase superfamily protein
ICDKHGKO_00361 8.3e-280 gerKA EG Spore germination protein
ICDKHGKO_00362 1.6e-227 gerKC S spore germination
ICDKHGKO_00363 2.9e-191 gerKB F Spore germination protein
ICDKHGKO_00364 1.2e-247 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICDKHGKO_00365 2.2e-90 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICDKHGKO_00366 3.4e-138 yxeM M Belongs to the bacterial solute-binding protein 3 family
ICDKHGKO_00367 1.7e-114 yxeN P COG0765 ABC-type amino acid transport system, permease component
ICDKHGKO_00368 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
ICDKHGKO_00369 1.6e-213 yxeP 3.5.1.47 E hydrolase activity
ICDKHGKO_00370 4.1e-240 yxeQ S MmgE/PrpD family
ICDKHGKO_00371 1.8e-119 yclH P ABC transporter
ICDKHGKO_00372 1.1e-222 yclI V ABC transporter (permease) YclI
ICDKHGKO_00373 9.9e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICDKHGKO_00374 9.5e-256 T PhoQ Sensor
ICDKHGKO_00375 2.7e-75 S aspartate phosphatase
ICDKHGKO_00378 1.7e-246 lysC 2.7.2.4 E Belongs to the aspartokinase family
ICDKHGKO_00379 6.3e-163 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICDKHGKO_00380 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICDKHGKO_00381 5.8e-135 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
ICDKHGKO_00382 7.4e-172 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
ICDKHGKO_00383 1.2e-245 ycnB EGP Major facilitator Superfamily
ICDKHGKO_00384 1.1e-148 ycnC K Transcriptional regulator
ICDKHGKO_00385 1.4e-133 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
ICDKHGKO_00386 1.4e-44 ycnE S Monooxygenase
ICDKHGKO_00387 1.8e-50 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
ICDKHGKO_00388 2.7e-255 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ICDKHGKO_00389 5.5e-210 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICDKHGKO_00390 1.3e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ICDKHGKO_00391 2.6e-147 glcU U Glucose uptake
ICDKHGKO_00392 8.6e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICDKHGKO_00393 6.2e-95 ycnI S protein conserved in bacteria
ICDKHGKO_00394 3.5e-286 ycnJ P protein, homolog of Cu resistance protein CopC
ICDKHGKO_00395 8.4e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
ICDKHGKO_00396 4.3e-53
ICDKHGKO_00397 2.1e-231 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
ICDKHGKO_00398 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
ICDKHGKO_00399 1.8e-201 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
ICDKHGKO_00400 2.7e-59 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
ICDKHGKO_00402 2.6e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
ICDKHGKO_00403 2.1e-132 ycsF S Belongs to the UPF0271 (lamB) family
ICDKHGKO_00404 1.8e-207 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
ICDKHGKO_00405 1.1e-141 ycsI S Belongs to the D-glutamate cyclase family
ICDKHGKO_00406 6.4e-131 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
ICDKHGKO_00407 9.7e-178 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
ICDKHGKO_00408 4.3e-125 kipR K Transcriptional regulator
ICDKHGKO_00409 1.2e-112 ycsK E anatomical structure formation involved in morphogenesis
ICDKHGKO_00411 1.1e-53 yczJ S biosynthesis
ICDKHGKO_00412 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
ICDKHGKO_00413 6.8e-167 ydhF S Oxidoreductase
ICDKHGKO_00414 0.0 mtlR K transcriptional regulator, MtlR
ICDKHGKO_00415 7.4e-283 ydaB IQ acyl-CoA ligase
ICDKHGKO_00416 2.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICDKHGKO_00417 9.6e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
ICDKHGKO_00418 3e-113 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ICDKHGKO_00419 3.4e-76 ydaG 1.4.3.5 S general stress protein
ICDKHGKO_00420 1.2e-135 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
ICDKHGKO_00421 3.9e-47 ydzA EGP Major facilitator Superfamily
ICDKHGKO_00422 4.3e-74 lrpC K Transcriptional regulator
ICDKHGKO_00423 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICDKHGKO_00424 2.9e-188 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
ICDKHGKO_00425 6.5e-143 ydaK T Diguanylate cyclase, GGDEF domain
ICDKHGKO_00426 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
ICDKHGKO_00427 8.8e-229 ydaM M Glycosyl transferase family group 2
ICDKHGKO_00428 0.0 ydaN S Bacterial cellulose synthase subunit
ICDKHGKO_00429 0.0 ydaO E amino acid
ICDKHGKO_00430 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
ICDKHGKO_00431 7.1e-61 K acetyltransferase
ICDKHGKO_00432 2.8e-87 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ICDKHGKO_00433 1.9e-65
ICDKHGKO_00434 2e-183 S Histidine kinase
ICDKHGKO_00437 4.7e-39
ICDKHGKO_00438 1.9e-223 mntH P H( )-stimulated, divalent metal cation uptake system
ICDKHGKO_00441 5.5e-33 ydaT
ICDKHGKO_00442 5.8e-73 yvaD S Family of unknown function (DUF5360)
ICDKHGKO_00443 1.1e-48 yvaE P Small Multidrug Resistance protein
ICDKHGKO_00444 1.2e-135 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
ICDKHGKO_00446 7e-56 ydbB G Cupin domain
ICDKHGKO_00447 5.1e-57 ydbC S Domain of unknown function (DUF4937
ICDKHGKO_00448 2.3e-153 ydbD P Catalase
ICDKHGKO_00449 1.4e-41 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
ICDKHGKO_00450 3.6e-135 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
ICDKHGKO_00451 1.3e-293 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
ICDKHGKO_00452 1.1e-113 dctR T COG4565 Response regulator of citrate malate metabolism
ICDKHGKO_00453 3.2e-223 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICDKHGKO_00454 2.2e-156 ydbI S AI-2E family transporter
ICDKHGKO_00455 5.7e-169 ydbJ V ABC transporter, ATP-binding protein
ICDKHGKO_00456 7.7e-127 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
ICDKHGKO_00457 4.6e-52 ydbL
ICDKHGKO_00458 2.7e-200 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
ICDKHGKO_00459 3.5e-12 S Fur-regulated basic protein B
ICDKHGKO_00460 9.2e-10 S Fur-regulated basic protein A
ICDKHGKO_00461 4.4e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICDKHGKO_00462 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ICDKHGKO_00463 1.3e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ICDKHGKO_00464 3.7e-249 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ICDKHGKO_00465 1.8e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ICDKHGKO_00466 4.6e-61 ydbS S Bacterial PH domain
ICDKHGKO_00467 6.6e-252 ydbT S Membrane
ICDKHGKO_00468 5.8e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
ICDKHGKO_00469 4.1e-54 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ICDKHGKO_00470 1.3e-179 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
ICDKHGKO_00471 3.9e-215 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICDKHGKO_00472 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
ICDKHGKO_00473 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
ICDKHGKO_00474 3e-137 rsbR T Positive regulator of sigma-B
ICDKHGKO_00475 1.8e-57 rsbS T antagonist
ICDKHGKO_00476 4.2e-68 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
ICDKHGKO_00477 1.8e-184 rsbU 3.1.3.3 KT phosphatase
ICDKHGKO_00478 4.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
ICDKHGKO_00479 6.6e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
ICDKHGKO_00480 2e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICDKHGKO_00481 2.5e-104 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
ICDKHGKO_00482 0.0 yhgF K COG2183 Transcriptional accessory protein
ICDKHGKO_00483 1.7e-14
ICDKHGKO_00484 4.6e-80 ydcK S Belongs to the SprT family
ICDKHGKO_00493 8.6e-48 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ICDKHGKO_00495 3.1e-08 O Glutaredoxin
ICDKHGKO_00497 1.7e-30 fliA K RNA polymerase
ICDKHGKO_00498 2.3e-13
ICDKHGKO_00499 2.2e-12
ICDKHGKO_00500 1.2e-15 S YesK-like protein
ICDKHGKO_00501 9.5e-195 L Belongs to the 'phage' integrase family
ICDKHGKO_00502 5.8e-62 immA E Pfam:DUF955
ICDKHGKO_00503 5.6e-54 yvaO K Transcriptional
ICDKHGKO_00504 1.3e-24
ICDKHGKO_00506 8.4e-39 S Bacterial protein of unknown function (DUF961)
ICDKHGKO_00507 9.6e-07
ICDKHGKO_00508 9.5e-240 ydcQ D Ftsk spoiiie family protein
ICDKHGKO_00509 6.3e-180 nicK L Replication initiation factor
ICDKHGKO_00513 1.1e-36 yddA
ICDKHGKO_00517 2e-125 yddB S Conjugative transposon protein TcpC
ICDKHGKO_00518 1.4e-24 yddC
ICDKHGKO_00519 3.6e-75 yddD S TcpE family
ICDKHGKO_00520 0.0 yddE S AAA-like domain
ICDKHGKO_00521 2.2e-35 S Domain of unknown function (DUF1874)
ICDKHGKO_00522 1.2e-210 yddG S maturation of SSU-rRNA
ICDKHGKO_00523 5e-158 yddH CBM50 M Lysozyme-like
ICDKHGKO_00524 2.1e-56 yddI
ICDKHGKO_00525 5.3e-36 S Domain of unknown function with cystatin-like fold (DUF4467)
ICDKHGKO_00526 7.7e-60
ICDKHGKO_00529 1e-11 S Type II restriction endonuclease EcoO109I
ICDKHGKO_00530 3.5e-144 sinIM 2.1.1.37 L C-5 cytosine-specific DNA methylase
ICDKHGKO_00531 1.5e-73 S response regulator aspartate phosphatase
ICDKHGKO_00533 2.7e-50 S SMI1-KNR4 cell-wall
ICDKHGKO_00534 4.2e-200 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
ICDKHGKO_00535 4.9e-54
ICDKHGKO_00536 8.2e-77 K Transcriptional regulator
ICDKHGKO_00537 2.3e-95 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICDKHGKO_00538 5.1e-30 cspL K Cold shock
ICDKHGKO_00539 8.9e-111 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
ICDKHGKO_00540 3.1e-101 S Protein of unknown function (DUF2812)
ICDKHGKO_00541 1.6e-49 K Transcriptional regulator PadR-like family
ICDKHGKO_00542 7.4e-237 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ICDKHGKO_00543 5.9e-188 ydeG EGP Major facilitator superfamily
ICDKHGKO_00544 1.1e-50 S Patatin-like phospholipase
ICDKHGKO_00545 7e-45 S Patatin-like phospholipase
ICDKHGKO_00547 4.9e-254 ygaK C COG0277 FAD FMN-containing dehydrogenases
ICDKHGKO_00548 1.8e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICDKHGKO_00549 1.1e-151 czcD P COG1230 Co Zn Cd efflux system component
ICDKHGKO_00550 1.4e-160 S SNARE associated Golgi protein
ICDKHGKO_00551 5.8e-97 yrkC G Cupin domain
ICDKHGKO_00552 1.8e-82 yyaR K Acetyltransferase (GNAT) domain
ICDKHGKO_00553 6.6e-146 ydeE K AraC family transcriptional regulator
ICDKHGKO_00555 2.6e-186 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
ICDKHGKO_00556 7.1e-47 ydeH
ICDKHGKO_00557 1.3e-160 S Sodium Bile acid symporter family
ICDKHGKO_00558 5.1e-198 adhA 1.1.1.1 C alcohol dehydrogenase
ICDKHGKO_00559 5e-61 yraB K helix_turn_helix, mercury resistance
ICDKHGKO_00560 1.4e-218 mleN_2 C antiporter
ICDKHGKO_00561 4.6e-247 K helix_turn_helix gluconate operon transcriptional repressor
ICDKHGKO_00562 2.6e-101 paiB K Transcriptional regulator
ICDKHGKO_00563 7.4e-169 ydeR EGP Major facilitator Superfamily
ICDKHGKO_00564 1.8e-99 ydeS K Transcriptional regulator
ICDKHGKO_00565 5.7e-150 ydeK EG -transporter
ICDKHGKO_00566 9e-251 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ICDKHGKO_00567 2.6e-46 yraD M Spore coat protein
ICDKHGKO_00568 3.1e-24 yraE
ICDKHGKO_00569 9.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
ICDKHGKO_00570 8.4e-63 yraF M Spore coat protein
ICDKHGKO_00571 8.4e-35 yraG
ICDKHGKO_00572 2.3e-35 ydfJ S drug exporters of the RND superfamily
ICDKHGKO_00573 1.2e-126 puuD S Peptidase C26
ICDKHGKO_00574 2.6e-289 expZ S ABC transporter
ICDKHGKO_00575 3.6e-91 ynaD J Acetyltransferase (GNAT) domain
ICDKHGKO_00576 1.5e-147 S Uncharacterized protein conserved in bacteria (DUF2179)
ICDKHGKO_00577 3.3e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
ICDKHGKO_00578 2e-206 tcaB EGP Major facilitator Superfamily
ICDKHGKO_00579 1.8e-218 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICDKHGKO_00580 6.2e-154 K Helix-turn-helix XRE-family like proteins
ICDKHGKO_00581 1.1e-122 ydhB S membrane transporter protein
ICDKHGKO_00582 2e-77 bltD 2.3.1.57 K FR47-like protein
ICDKHGKO_00583 2.6e-141 bltR K helix_turn_helix, mercury resistance
ICDKHGKO_00584 3e-143 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ICDKHGKO_00585 9.3e-107 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
ICDKHGKO_00586 7.5e-105 S Alpha/beta hydrolase family
ICDKHGKO_00587 5.7e-165 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
ICDKHGKO_00588 1.3e-112 ydhC K FCD
ICDKHGKO_00589 1.2e-55 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
ICDKHGKO_00590 1.4e-133 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
ICDKHGKO_00592 2.5e-245 pbpE V Beta-lactamase
ICDKHGKO_00594 1.2e-97 ydhK M Protein of unknown function (DUF1541)
ICDKHGKO_00595 3.2e-193 pbuE EGP Major facilitator Superfamily
ICDKHGKO_00596 3.1e-130 ydhQ K UTRA
ICDKHGKO_00597 2.1e-112 K FCD
ICDKHGKO_00598 8.2e-208 yeaN P COG2807 Cyanate permease
ICDKHGKO_00599 1.1e-47 sugE P Small Multidrug Resistance protein
ICDKHGKO_00600 3.1e-48 ykkC P Small Multidrug Resistance protein
ICDKHGKO_00601 2e-98 yvdT K Transcriptional regulator
ICDKHGKO_00602 8.2e-293 yveA E amino acid
ICDKHGKO_00603 1.4e-161 ydhU P Catalase
ICDKHGKO_00604 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
ICDKHGKO_00605 1.6e-177 yhfP 1.1.1.1 C Quinone oxidoreductase
ICDKHGKO_00606 4e-246 iolT EGP Major facilitator Superfamily
ICDKHGKO_00609 2.2e-38 S COG NOG14552 non supervised orthologous group
ICDKHGKO_00610 7.8e-08
ICDKHGKO_00612 4.1e-173 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ICDKHGKO_00613 3.2e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
ICDKHGKO_00614 5.1e-122 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
ICDKHGKO_00615 9e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
ICDKHGKO_00616 8.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICDKHGKO_00617 9.1e-310 ydiF S ABC transporter
ICDKHGKO_00618 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
ICDKHGKO_00619 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ICDKHGKO_00620 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
ICDKHGKO_00621 1.2e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ICDKHGKO_00622 1.7e-27 ydiK S Domain of unknown function (DUF4305)
ICDKHGKO_00623 5.3e-125 ydiL S CAAX protease self-immunity
ICDKHGKO_00624 6.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ICDKHGKO_00625 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ICDKHGKO_00626 2.3e-77 S Phage integrase family
ICDKHGKO_00627 2.4e-30 yqaB E IrrE N-terminal-like domain
ICDKHGKO_00628 1.7e-25 S Protein of unknown function (DUF4064)
ICDKHGKO_00629 1.3e-48
ICDKHGKO_00630 7.9e-16 K Helix-turn-helix XRE-family like proteins
ICDKHGKO_00631 1.5e-12 K Helix-turn-helix XRE-family like proteins
ICDKHGKO_00632 3.8e-32
ICDKHGKO_00633 9.6e-61 S DNA binding
ICDKHGKO_00634 4.2e-85
ICDKHGKO_00636 1.2e-07 S Hypothetical protein Yqai
ICDKHGKO_00638 5.9e-153 yqaJ L YqaJ-like viral recombinase domain
ICDKHGKO_00639 2.9e-127 recT L RecT family
ICDKHGKO_00640 1.4e-29 3.1.3.16 L DnaD domain protein
ICDKHGKO_00641 2.4e-120 xkdC L IstB-like ATP binding protein
ICDKHGKO_00643 2.3e-22 S YopX protein
ICDKHGKO_00644 6.8e-54 S Protein of unknown function (DUF1064)
ICDKHGKO_00646 5e-17 yqaO S Phage-like element PBSX protein XtrA
ICDKHGKO_00649 7.2e-168 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
ICDKHGKO_00651 1.2e-42 S dUTPase
ICDKHGKO_00654 5.6e-07 S YopX protein
ICDKHGKO_00659 3.1e-48
ICDKHGKO_00661 5.3e-19 V VanZ like family
ICDKHGKO_00662 1.6e-67 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
ICDKHGKO_00664 3.9e-12 K Transcriptional regulator
ICDKHGKO_00667 1.5e-71 yqaS L DNA packaging
ICDKHGKO_00668 6.4e-179 S Pfam:Terminase_3C
ICDKHGKO_00669 1.1e-126 S Phage portal protein, SPP1 Gp6-like
ICDKHGKO_00670 1.5e-92 S Phage Mu protein F like protein
ICDKHGKO_00672 5.4e-44 S Phage minor structural protein GP20
ICDKHGKO_00673 2.9e-54 gpG
ICDKHGKO_00676 3.5e-27 S Phage gp6-like head-tail connector protein
ICDKHGKO_00677 9.5e-29 S Phage head-tail joining protein
ICDKHGKO_00678 6.2e-38 S Bacteriophage HK97-gp10, putative tail-component
ICDKHGKO_00679 3.8e-29 S Protein of unknown function (DUF3168)
ICDKHGKO_00680 1.3e-34 S Phage tail tube protein
ICDKHGKO_00681 1.9e-25 S Phage tail assembly chaperone protein, TAC
ICDKHGKO_00682 9.3e-136
ICDKHGKO_00683 3.5e-47
ICDKHGKO_00684 1.6e-202 sidC L Phage minor structural protein
ICDKHGKO_00688 2.4e-30 xhlA S Haemolysin XhlA
ICDKHGKO_00689 4.8e-28 xhlB S SPP1 phage holin
ICDKHGKO_00690 6.1e-121 xlyB 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ICDKHGKO_00693 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
ICDKHGKO_00695 5.7e-62
ICDKHGKO_00696 0.0 K NB-ARC domain
ICDKHGKO_00697 3.3e-197 gutB 1.1.1.14 E Dehydrogenase
ICDKHGKO_00698 4.7e-244 gutA G MFS/sugar transport protein
ICDKHGKO_00699 3e-165 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
ICDKHGKO_00700 2.1e-30 yjdJ S Domain of unknown function (DUF4306)
ICDKHGKO_00701 3.1e-111 pspA KT Phage shock protein A
ICDKHGKO_00702 1.7e-174 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICDKHGKO_00703 1.1e-114 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
ICDKHGKO_00704 2e-143 ydjI S virion core protein (lumpy skin disease virus)
ICDKHGKO_00705 0.0 yrhL I Acyltransferase family
ICDKHGKO_00706 2.6e-139 rsiV S Protein of unknown function (DUF3298)
ICDKHGKO_00707 9.5e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
ICDKHGKO_00708 6.4e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
ICDKHGKO_00709 4.2e-62 ydjM M Lytic transglycolase
ICDKHGKO_00710 1.8e-131 ydjN U Involved in the tonB-independent uptake of proteins
ICDKHGKO_00712 3.2e-34 ydjO S Cold-inducible protein YdjO
ICDKHGKO_00713 9.5e-302 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
ICDKHGKO_00714 3.9e-238 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
ICDKHGKO_00715 2.2e-140 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICDKHGKO_00716 3e-176 yeaC S COG0714 MoxR-like ATPases
ICDKHGKO_00717 1.2e-198 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
ICDKHGKO_00718 0.0 yebA E COG1305 Transglutaminase-like enzymes
ICDKHGKO_00719 6.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ICDKHGKO_00720 1.5e-89 sigV K Belongs to the sigma-70 factor family. ECF subfamily
ICDKHGKO_00721 2.3e-249 S Domain of unknown function (DUF4179)
ICDKHGKO_00722 8.1e-209 pbuG S permease
ICDKHGKO_00723 2.4e-123 yebC M Membrane
ICDKHGKO_00725 1.5e-92 yebE S UPF0316 protein
ICDKHGKO_00726 9.5e-29 yebG S NETI protein
ICDKHGKO_00727 2.2e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ICDKHGKO_00728 7.7e-219 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ICDKHGKO_00729 1.8e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ICDKHGKO_00730 3.6e-126 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
ICDKHGKO_00731 4.2e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICDKHGKO_00732 1.2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICDKHGKO_00733 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICDKHGKO_00734 1.1e-267 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ICDKHGKO_00735 8.7e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
ICDKHGKO_00736 5.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICDKHGKO_00737 7.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
ICDKHGKO_00738 4.7e-230 purD 6.3.4.13 F Belongs to the GARS family
ICDKHGKO_00739 3.8e-62 K helix_turn_helix ASNC type
ICDKHGKO_00740 4.2e-135 yjeH E Amino acid permease
ICDKHGKO_00741 5.4e-25 S Protein of unknown function (DUF2892)
ICDKHGKO_00742 0.0 yerA 3.5.4.2 F adenine deaminase
ICDKHGKO_00743 2.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
ICDKHGKO_00744 2.4e-50 yerC S protein conserved in bacteria
ICDKHGKO_00745 6.1e-296 yerD 1.4.7.1 E Belongs to the glutamate synthase family
ICDKHGKO_00746 9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ICDKHGKO_00747 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
ICDKHGKO_00748 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ICDKHGKO_00749 5.2e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
ICDKHGKO_00750 5.4e-181 yerI S homoserine kinase type II (protein kinase fold)
ICDKHGKO_00751 3.1e-119 sapB S MgtC SapB transporter
ICDKHGKO_00752 4.9e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICDKHGKO_00753 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICDKHGKO_00754 2e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ICDKHGKO_00755 1.5e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ICDKHGKO_00756 1.1e-147 yerO K Transcriptional regulator
ICDKHGKO_00757 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICDKHGKO_00758 7.4e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
ICDKHGKO_00759 1.6e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICDKHGKO_00760 1.9e-310 L Uncharacterized conserved protein (DUF2075)
ICDKHGKO_00761 8.5e-160 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
ICDKHGKO_00762 1.4e-137 cylB V ABC-2 type transporter
ICDKHGKO_00763 8.1e-33 S Protein of unknown function, DUF600
ICDKHGKO_00764 1.5e-56 S Protein of unknown function, DUF600
ICDKHGKO_00765 1.9e-51 S Protein of unknown function, DUF600
ICDKHGKO_00766 7.8e-198 yobL L nucleic acid phosphodiester bond hydrolysis
ICDKHGKO_00767 1.3e-120 yobL L Belongs to the WXG100 family
ICDKHGKO_00768 2.7e-126 yeeN K transcriptional regulatory protein
ICDKHGKO_00770 1.7e-109 aadK G Streptomycin adenylyltransferase
ICDKHGKO_00771 9.1e-45 cotJA S Spore coat associated protein JA (CotJA)
ICDKHGKO_00772 1.3e-44 cotJB S CotJB protein
ICDKHGKO_00773 2e-103 cotJC P Spore Coat
ICDKHGKO_00774 2.2e-88 yesJ K Acetyltransferase (GNAT) family
ICDKHGKO_00776 3e-114 yetF S membrane
ICDKHGKO_00777 7e-53 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
ICDKHGKO_00778 7e-62 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICDKHGKO_00779 3.7e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ICDKHGKO_00780 1.4e-20 yezD S Uncharacterized small protein (DUF2292)
ICDKHGKO_00781 2.4e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
ICDKHGKO_00782 2e-104 yetJ S Belongs to the BI1 family
ICDKHGKO_00783 4.9e-85 yetL K helix_turn_helix multiple antibiotic resistance protein
ICDKHGKO_00784 8.1e-194 yetM CH FAD binding domain
ICDKHGKO_00785 1.7e-196 yetN S Protein of unknown function (DUF3900)
ICDKHGKO_00786 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
ICDKHGKO_00788 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ICDKHGKO_00789 4.3e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
ICDKHGKO_00790 9.2e-172 yfnG 4.2.1.45 M dehydratase
ICDKHGKO_00791 8.4e-173 yfnF M Nucleotide-diphospho-sugar transferase
ICDKHGKO_00792 4.3e-214 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
ICDKHGKO_00793 4.5e-177 yfnD M Nucleotide-diphospho-sugar transferase
ICDKHGKO_00794 1.5e-212 fsr P COG0477 Permeases of the major facilitator superfamily
ICDKHGKO_00795 7.6e-242 yfnA E amino acid
ICDKHGKO_00796 3.2e-275 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ICDKHGKO_00797 1.1e-105 yfmS NT chemotaxis protein
ICDKHGKO_00798 6.4e-165 IQ Enoyl-(Acyl carrier protein) reductase
ICDKHGKO_00799 6.5e-201 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ICDKHGKO_00800 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ICDKHGKO_00801 5.8e-68 yfmP K transcriptional
ICDKHGKO_00802 3.2e-196 yfmO EGP Major facilitator Superfamily
ICDKHGKO_00803 4.6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ICDKHGKO_00804 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
ICDKHGKO_00805 3.7e-51 yfmJ S N-terminal domain of oxidoreductase
ICDKHGKO_00806 5.7e-79 yfmJ S N-terminal domain of oxidoreductase
ICDKHGKO_00807 4.1e-25 S Protein of unknown function (DUF3212)
ICDKHGKO_00808 1.3e-57 yflT S Heat induced stress protein YflT
ICDKHGKO_00809 2e-233 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
ICDKHGKO_00810 1e-233 yflS P Sodium:sulfate symporter transmembrane region
ICDKHGKO_00811 4.3e-26 Q PFAM Collagen triple helix
ICDKHGKO_00813 1.2e-19 Q calcium- and calmodulin-responsive adenylate cyclase activity
ICDKHGKO_00814 4.5e-76 M1-820 Q Collagen triple helix repeat (20 copies)
ICDKHGKO_00815 0.0 ywpD T PhoQ Sensor
ICDKHGKO_00816 4.8e-151 M1-574 T Transcriptional regulatory protein, C terminal
ICDKHGKO_00817 0.0 M1-568 M cell wall anchor domain
ICDKHGKO_00818 4.6e-80 srtA 3.4.22.70 M Sortase family
ICDKHGKO_00819 1.1e-265 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
ICDKHGKO_00820 6e-115 citT T response regulator
ICDKHGKO_00821 1.7e-171 yflP S Tripartite tricarboxylate transporter family receptor
ICDKHGKO_00822 7.4e-223 citM C Citrate transporter
ICDKHGKO_00823 4.6e-143 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
ICDKHGKO_00824 1.9e-211 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ICDKHGKO_00825 1.3e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
ICDKHGKO_00826 2.3e-119 yflK S protein conserved in bacteria
ICDKHGKO_00827 1.5e-14 yflJ S Protein of unknown function (DUF2639)
ICDKHGKO_00828 1.6e-18 yflI
ICDKHGKO_00829 9e-50 yflH S Protein of unknown function (DUF3243)
ICDKHGKO_00830 6.8e-136 map 3.4.11.18 E Methionine aminopeptidase
ICDKHGKO_00831 5.4e-240 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
ICDKHGKO_00832 8.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
ICDKHGKO_00833 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ICDKHGKO_00834 4.7e-61 yhdN S Domain of unknown function (DUF1992)
ICDKHGKO_00835 4.5e-76 cotP O Belongs to the small heat shock protein (HSP20) family
ICDKHGKO_00836 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
ICDKHGKO_00837 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
ICDKHGKO_00838 2.3e-238 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ICDKHGKO_00839 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
ICDKHGKO_00840 6.1e-126 treR K transcriptional
ICDKHGKO_00841 4.6e-120 yfkO C nitroreductase
ICDKHGKO_00842 3.8e-118 yibF S YibE/F-like protein
ICDKHGKO_00843 6.8e-185 yibE S YibE/F-like protein
ICDKHGKO_00844 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
ICDKHGKO_00845 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
ICDKHGKO_00846 2.6e-178 K helix_turn _helix lactose operon repressor
ICDKHGKO_00847 3.2e-161 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICDKHGKO_00848 4e-128 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
ICDKHGKO_00849 8.4e-189 ydiM EGP Major facilitator Superfamily
ICDKHGKO_00850 3.9e-28 yfkK S Belongs to the UPF0435 family
ICDKHGKO_00851 2.2e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICDKHGKO_00852 4.4e-47 yfkI S gas vesicle protein
ICDKHGKO_00853 7.1e-142 yihY S Belongs to the UPF0761 family
ICDKHGKO_00854 1.1e-214 ycaD EGP COG0477 Permeases of the major facilitator superfamily
ICDKHGKO_00855 1.5e-181 cax P COG0387 Ca2 H antiporter
ICDKHGKO_00856 1.1e-139 yfkD S YfkD-like protein
ICDKHGKO_00857 5.4e-142 yfkC M Mechanosensitive ion channel
ICDKHGKO_00858 2.1e-218 yfkA S YfkB-like domain
ICDKHGKO_00859 4.9e-27 yfjT
ICDKHGKO_00860 4.9e-153 pdaA G deacetylase
ICDKHGKO_00861 6.2e-45 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
ICDKHGKO_00862 1.2e-68 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
ICDKHGKO_00863 1.8e-28
ICDKHGKO_00864 2.5e-183 corA P Mediates influx of magnesium ions
ICDKHGKO_00865 2.8e-157 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ICDKHGKO_00866 3.4e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICDKHGKO_00867 1.3e-79 O Subtilase family
ICDKHGKO_00868 1.3e-246 lmrA 3.6.3.44 V ABC transporter
ICDKHGKO_00869 0.0 KLT Protein kinase domain
ICDKHGKO_00877 4.7e-45 S YfzA-like protein
ICDKHGKO_00878 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICDKHGKO_00879 6e-79 yfjM S Psort location Cytoplasmic, score
ICDKHGKO_00880 2.5e-186 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ICDKHGKO_00881 2e-186 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ICDKHGKO_00882 6.8e-207 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICDKHGKO_00883 3.9e-238 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ICDKHGKO_00884 3.8e-158 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
ICDKHGKO_00885 5.4e-106 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
ICDKHGKO_00886 3.2e-15 sspH S Belongs to the SspH family
ICDKHGKO_00887 1e-259 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
ICDKHGKO_00888 4.3e-138 glvR F Helix-turn-helix domain, rpiR family
ICDKHGKO_00889 2.4e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ICDKHGKO_00890 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
ICDKHGKO_00891 1.9e-303 yfiB3 V ABC transporter
ICDKHGKO_00892 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
ICDKHGKO_00893 9.2e-63 mhqP S DoxX
ICDKHGKO_00894 1.5e-155 yfiE 1.13.11.2 S glyoxalase
ICDKHGKO_00895 3.7e-77 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
ICDKHGKO_00896 1.7e-70 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
ICDKHGKO_00897 2e-92 padR K transcriptional
ICDKHGKO_00898 9.7e-101 1.6.5.2 S NADPH-dependent FMN reductase
ICDKHGKO_00899 8.5e-172 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ICDKHGKO_00900 2.2e-44 yrdF K ribonuclease inhibitor
ICDKHGKO_00901 6.1e-94 yfiT S Belongs to the metal hydrolase YfiT family
ICDKHGKO_00902 3.2e-284 yfiU EGP Major facilitator Superfamily
ICDKHGKO_00903 2.4e-78 yfiV K transcriptional
ICDKHGKO_00904 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ICDKHGKO_00905 5.5e-153 yfhB 5.3.3.17 S PhzF family
ICDKHGKO_00906 5.9e-103 yfhC C nitroreductase
ICDKHGKO_00907 1e-24 yfhD S YfhD-like protein
ICDKHGKO_00909 2.1e-163 yfhF S nucleoside-diphosphate sugar epimerase
ICDKHGKO_00910 3.1e-139 recX 2.4.1.337 GT4 S Modulates RecA activity
ICDKHGKO_00911 4.7e-46 yfhH S Protein of unknown function (DUF1811)
ICDKHGKO_00912 5e-177 yfhI EGP Major facilitator Superfamily
ICDKHGKO_00914 9.4e-156 mpr 3.4.21.19 M Belongs to the peptidase S1B family
ICDKHGKO_00915 8.3e-44 yfhJ S WVELL protein
ICDKHGKO_00916 1.2e-86 batE T Bacterial SH3 domain homologues
ICDKHGKO_00917 2e-31 yfhL S SdpI/YhfL protein family
ICDKHGKO_00918 6.1e-123 yfhM S Alpha/beta hydrolase family
ICDKHGKO_00919 1.1e-183 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ICDKHGKO_00920 0.0 yfhO S Bacterial membrane protein YfhO
ICDKHGKO_00921 5.9e-180 yfhP S membrane-bound metal-dependent
ICDKHGKO_00922 1.4e-203 mutY L A G-specific
ICDKHGKO_00923 1.8e-36 yfhS
ICDKHGKO_00924 2e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICDKHGKO_00926 1.5e-37 ygaB S YgaB-like protein
ICDKHGKO_00927 2.2e-104 ygaC J Belongs to the UPF0374 family
ICDKHGKO_00928 3.1e-301 ygaD V ABC transporter
ICDKHGKO_00929 5e-177 ygaE S Membrane
ICDKHGKO_00930 1.1e-242 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
ICDKHGKO_00931 5e-84 bcp 1.11.1.15 O Peroxiredoxin
ICDKHGKO_00932 3.1e-80 perR P Belongs to the Fur family
ICDKHGKO_00933 2.1e-55 ygzB S UPF0295 protein
ICDKHGKO_00934 8.5e-162 ygxA S Nucleotidyltransferase-like
ICDKHGKO_00935 2.2e-38 S COG NOG14552 non supervised orthologous group
ICDKHGKO_00940 7.8e-08
ICDKHGKO_00948 1.6e-08
ICDKHGKO_00952 6.8e-132 L Phage integrase family
ICDKHGKO_00953 7.3e-70
ICDKHGKO_00956 1.1e-28 K Helix-turn-helix XRE-family like proteins
ICDKHGKO_00958 2.2e-38 S Domain of unknown function (DUF771)
ICDKHGKO_00960 2e-83 ybl78 L Conserved phage C-terminus (Phg_2220_C)
ICDKHGKO_00961 3.4e-35 dnaC L IstB-like ATP binding protein
ICDKHGKO_00964 2e-28
ICDKHGKO_00967 1.6e-15 yqaO S Phage-like element PBSX protein XtrA
ICDKHGKO_00969 1.2e-27
ICDKHGKO_00971 4.4e-168 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
ICDKHGKO_00973 1.6e-46 S dUTPase
ICDKHGKO_00978 2.5e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
ICDKHGKO_00979 1e-72 L Phage integrase family
ICDKHGKO_00980 6.9e-09 ftsK D PFAM cell divisionFtsK SpoIIIE
ICDKHGKO_00984 1.8e-16 V HNH endonuclease
ICDKHGKO_00985 3.6e-45
ICDKHGKO_00986 8.9e-277 L Phage Terminase
ICDKHGKO_00987 2.9e-179 S Phage portal protein
ICDKHGKO_00988 1.1e-84 clpP 3.4.21.92 OU Clp protease
ICDKHGKO_00989 1.2e-140 S Phage capsid family
ICDKHGKO_00991 2e-21
ICDKHGKO_00992 1.5e-22 S Phage head-tail joining protein
ICDKHGKO_00993 5.8e-18
ICDKHGKO_00994 7e-10 S TIGRFAM phage protein, HK97 gp10 family
ICDKHGKO_00995 6.4e-47 S phage major tail protein, phi13 family
ICDKHGKO_00998 9.4e-142 D Phage-related minor tail protein
ICDKHGKO_00999 1.2e-40 S Phage tail protein
ICDKHGKO_01000 1e-103 mur1 NU Prophage endopeptidase tail
ICDKHGKO_01001 1.3e-284 M Pectate lyase superfamily protein
ICDKHGKO_01002 2.5e-143 S Domain of unknown function (DUF2479)
ICDKHGKO_01004 2.3e-09 S Phage uncharacterised protein (Phage_XkdX)
ICDKHGKO_01005 6.9e-61 S Pfam:Phage_holin_4_1
ICDKHGKO_01006 5e-69 3.5.1.28 M Ami_2
ICDKHGKO_01007 2e-16
ICDKHGKO_01008 1.4e-39
ICDKHGKO_01010 5.9e-275 C Na+/H+ antiporter family
ICDKHGKO_01011 1.8e-122 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
ICDKHGKO_01012 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ICDKHGKO_01013 1.3e-246 ygaK C Berberine and berberine like
ICDKHGKO_01015 2.4e-229 oppA5 E PFAM extracellular solute-binding protein family 5
ICDKHGKO_01016 3.5e-145 appB P Binding-protein-dependent transport system inner membrane component
ICDKHGKO_01017 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICDKHGKO_01018 9.8e-135 oppD3 P Belongs to the ABC transporter superfamily
ICDKHGKO_01019 2.9e-131 oppF3 E Belongs to the ABC transporter superfamily
ICDKHGKO_01020 4e-286 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
ICDKHGKO_01021 4.7e-179 S Amidohydrolase
ICDKHGKO_01022 4.3e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
ICDKHGKO_01023 2.5e-170 ssuA M Sulfonate ABC transporter
ICDKHGKO_01024 2.4e-142 ssuC P ABC transporter (permease)
ICDKHGKO_01025 8.2e-210 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
ICDKHGKO_01027 3.9e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICDKHGKO_01028 8.9e-78 ygaO
ICDKHGKO_01029 1.8e-22 K Transcriptional regulator
ICDKHGKO_01031 4.2e-107 yhzB S B3/4 domain
ICDKHGKO_01032 6.2e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ICDKHGKO_01033 2.9e-168 yhbB S Putative amidase domain
ICDKHGKO_01034 2.2e-84 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ICDKHGKO_01035 3.2e-102 yhbD K Protein of unknown function (DUF4004)
ICDKHGKO_01036 3.6e-54 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
ICDKHGKO_01037 1.3e-56 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
ICDKHGKO_01039 0.0 prkA T Ser protein kinase
ICDKHGKO_01040 1.8e-212 yhbH S Belongs to the UPF0229 family
ICDKHGKO_01041 1.6e-71 yhbI K DNA-binding transcription factor activity
ICDKHGKO_01042 4.4e-96 yhbJ V COG1566 Multidrug resistance efflux pump
ICDKHGKO_01043 4.1e-284 yhcA EGP Major facilitator Superfamily
ICDKHGKO_01044 1e-98 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
ICDKHGKO_01045 5.3e-49 yhcC
ICDKHGKO_01046 3.6e-52
ICDKHGKO_01047 1.7e-58 yhcF K Transcriptional regulator
ICDKHGKO_01048 2.8e-115 yhcG V ABC transporter, ATP-binding protein
ICDKHGKO_01049 1.9e-164 yhcH V ABC transporter, ATP-binding protein
ICDKHGKO_01050 7.9e-158 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
ICDKHGKO_01051 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
ICDKHGKO_01052 4.5e-125 metQ M Belongs to the nlpA lipoprotein family
ICDKHGKO_01053 4e-182 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
ICDKHGKO_01054 8.6e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICDKHGKO_01055 6.9e-40 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
ICDKHGKO_01056 4.4e-38 yhcM
ICDKHGKO_01057 6.3e-74 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ICDKHGKO_01058 1.3e-154 yhcP
ICDKHGKO_01059 9.4e-113 yhcQ M Spore coat protein
ICDKHGKO_01060 3.8e-298 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
ICDKHGKO_01061 6.9e-99 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
ICDKHGKO_01062 3.9e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICDKHGKO_01063 2.6e-62 yhcU S Family of unknown function (DUF5365)
ICDKHGKO_01064 8.4e-67 yhcV S COG0517 FOG CBS domain
ICDKHGKO_01065 1e-122 yhcW 5.4.2.6 S hydrolase
ICDKHGKO_01066 1.9e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
ICDKHGKO_01067 2.6e-255 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICDKHGKO_01068 1e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ICDKHGKO_01069 1.7e-143 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
ICDKHGKO_01070 8.9e-289 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ICDKHGKO_01071 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ICDKHGKO_01072 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
ICDKHGKO_01073 1.3e-194 yhcY 2.7.13.3 T Histidine kinase
ICDKHGKO_01074 2e-107 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICDKHGKO_01075 2.7e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
ICDKHGKO_01076 8e-38 yhdB S YhdB-like protein
ICDKHGKO_01077 1.3e-51 yhdC S Protein of unknown function (DUF3889)
ICDKHGKO_01078 2.3e-201 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
ICDKHGKO_01079 5.8e-71 nsrR K Transcriptional regulator
ICDKHGKO_01080 3.5e-248 ygxB M Conserved TM helix
ICDKHGKO_01081 4.2e-264 ycgB S Stage V sporulation protein R
ICDKHGKO_01082 6.2e-252 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
ICDKHGKO_01083 9.5e-123 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
ICDKHGKO_01084 2.8e-157 citR K Transcriptional regulator
ICDKHGKO_01085 1.6e-197 citA 2.3.3.1 C Belongs to the citrate synthase family
ICDKHGKO_01086 3.1e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICDKHGKO_01087 1.8e-246 yhdG E amino acid
ICDKHGKO_01088 1.6e-196 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
ICDKHGKO_01089 8.1e-45 yhdK S Sigma-M inhibitor protein
ICDKHGKO_01090 3.2e-195 yhdL S Sigma factor regulator N-terminal
ICDKHGKO_01091 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
ICDKHGKO_01092 5.8e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
ICDKHGKO_01093 4e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
ICDKHGKO_01094 1.8e-69 cueR K transcriptional
ICDKHGKO_01095 1.5e-217 yhdR 2.6.1.1 E Aminotransferase
ICDKHGKO_01096 3.3e-228 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICDKHGKO_01097 4.2e-248 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
ICDKHGKO_01098 8.8e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICDKHGKO_01099 3.4e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICDKHGKO_01100 1.2e-121 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ICDKHGKO_01102 2.1e-197 yhdY M Mechanosensitive ion channel
ICDKHGKO_01103 3.1e-133 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
ICDKHGKO_01104 1.4e-150 yheN G deacetylase
ICDKHGKO_01105 3.9e-148 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
ICDKHGKO_01106 3.7e-97 pksA K Transcriptional regulator
ICDKHGKO_01107 4.1e-90 ymcC S Membrane
ICDKHGKO_01108 1.3e-82 T universal stress protein
ICDKHGKO_01109 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
ICDKHGKO_01110 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
ICDKHGKO_01111 3.2e-99 yheG GM NAD(P)H-binding
ICDKHGKO_01113 3.8e-28 sspB S spore protein
ICDKHGKO_01114 1.7e-36 yheE S Family of unknown function (DUF5342)
ICDKHGKO_01115 1.1e-248 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
ICDKHGKO_01116 6.1e-202 yheC HJ YheC/D like ATP-grasp
ICDKHGKO_01117 8.5e-199 yheB S Belongs to the UPF0754 family
ICDKHGKO_01118 6.3e-52 yheA S Belongs to the UPF0342 family
ICDKHGKO_01119 2.7e-152 yhaX S haloacid dehalogenase-like hydrolase
ICDKHGKO_01120 1.1e-291 hemZ H coproporphyrinogen III oxidase
ICDKHGKO_01121 1.1e-245 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
ICDKHGKO_01122 2.5e-204 yhaU P COG0475 Kef-type K transport systems, membrane components
ICDKHGKO_01123 1.9e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
ICDKHGKO_01125 4.2e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
ICDKHGKO_01126 1.2e-14 S YhzD-like protein
ICDKHGKO_01127 5.9e-163 yhaQ S ABC transporter, ATP-binding protein
ICDKHGKO_01128 1.7e-203 yhaP CP COG1668 ABC-type Na efflux pump, permease component
ICDKHGKO_01129 9.1e-231 yhaO L DNA repair exonuclease
ICDKHGKO_01130 0.0 yhaN L AAA domain
ICDKHGKO_01131 1.1e-175 yhaM L Shows a 3'-5' exoribonuclease activity
ICDKHGKO_01132 2.3e-31 yhaL S Sporulation protein YhaL
ICDKHGKO_01133 3.2e-113 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ICDKHGKO_01134 1e-93 yhaK S Putative zincin peptidase
ICDKHGKO_01135 9.9e-55 yhaI S Protein of unknown function (DUF1878)
ICDKHGKO_01136 1.5e-109 hpr K Negative regulator of protease production and sporulation
ICDKHGKO_01137 9e-38 yhaH S YtxH-like protein
ICDKHGKO_01138 2e-17
ICDKHGKO_01139 1.3e-74 trpP S Tryptophan transporter TrpP
ICDKHGKO_01140 1.5e-197 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ICDKHGKO_01141 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
ICDKHGKO_01142 4.4e-135 ecsA V transporter (ATP-binding protein)
ICDKHGKO_01143 5.7e-217 ecsB U ABC transporter
ICDKHGKO_01144 1.1e-116 ecsC S EcsC protein family
ICDKHGKO_01145 1.4e-215 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
ICDKHGKO_01146 2.5e-237 yhfA C membrane
ICDKHGKO_01147 6e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
ICDKHGKO_01148 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ICDKHGKO_01149 1.9e-198 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ICDKHGKO_01150 1.7e-176 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
ICDKHGKO_01151 6.6e-273 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ICDKHGKO_01152 3.5e-100 yhgD K Transcriptional regulator
ICDKHGKO_01153 1.6e-255 yhgE S YhgE Pip N-terminal domain protein
ICDKHGKO_01154 1.3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICDKHGKO_01156 1.5e-194 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
ICDKHGKO_01157 1.2e-225 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ICDKHGKO_01158 6.2e-134 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
ICDKHGKO_01159 1.7e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
ICDKHGKO_01160 5.7e-107 yhfK GM NmrA-like family
ICDKHGKO_01161 1.7e-295 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
ICDKHGKO_01162 8.1e-64 yhfM
ICDKHGKO_01163 5.4e-231 yhfN 3.4.24.84 O Peptidase M48
ICDKHGKO_01164 1.6e-200 aprE 3.4.21.62 O Belongs to the peptidase S8 family
ICDKHGKO_01165 7e-129 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
ICDKHGKO_01166 2.7e-100 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
ICDKHGKO_01167 1.4e-193 vraB 2.3.1.9 I Belongs to the thiolase family
ICDKHGKO_01168 6.2e-263 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
ICDKHGKO_01169 3.1e-85 bioY S BioY family
ICDKHGKO_01170 2.4e-197 hemAT NT chemotaxis protein
ICDKHGKO_01171 1e-262 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
ICDKHGKO_01172 1.4e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICDKHGKO_01173 1.2e-30 yhzC S IDEAL
ICDKHGKO_01174 4.2e-109 comK K Competence transcription factor
ICDKHGKO_01175 4.1e-57 frataxin S Domain of unknown function (DU1801)
ICDKHGKO_01176 6.1e-171 els S Acetyltransferase, GNAT family
ICDKHGKO_01177 1.2e-121 yrpD S Domain of unknown function, YrpD
ICDKHGKO_01178 7.8e-42 yhjA S Excalibur calcium-binding domain
ICDKHGKO_01179 3.3e-47 S Belongs to the UPF0145 family
ICDKHGKO_01180 1.2e-261 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICDKHGKO_01181 3.1e-27 yhjC S Protein of unknown function (DUF3311)
ICDKHGKO_01182 7.9e-58 yhjD
ICDKHGKO_01183 1e-105 yhjE S SNARE associated Golgi protein
ICDKHGKO_01184 6.6e-90 sipV 3.4.21.89 U Belongs to the peptidase S26 family
ICDKHGKO_01185 1.3e-263 yhjG CH FAD binding domain
ICDKHGKO_01186 6.1e-91 yhjH K helix_turn_helix multiple antibiotic resistance protein
ICDKHGKO_01187 7.9e-184 abrB S membrane
ICDKHGKO_01188 2.6e-198 blt EGP Major facilitator Superfamily
ICDKHGKO_01189 3.5e-106 K QacR-like protein, C-terminal region
ICDKHGKO_01190 1.4e-82 yhjR S Rubrerythrin
ICDKHGKO_01191 1.2e-118 ydfS S Protein of unknown function (DUF421)
ICDKHGKO_01192 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
ICDKHGKO_01193 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
ICDKHGKO_01194 9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ICDKHGKO_01195 0.0 sbcC L COG0419 ATPase involved in DNA repair
ICDKHGKO_01196 3.9e-50 yisB V COG1403 Restriction endonuclease
ICDKHGKO_01197 1.7e-31 gerPF S Spore germination protein gerPA/gerPF
ICDKHGKO_01198 1e-58 gerPE S Spore germination protein GerPE
ICDKHGKO_01199 7.7e-22 gerPD S Spore germination protein
ICDKHGKO_01200 5.9e-61 gerPC S Spore germination protein
ICDKHGKO_01201 1.4e-31 gerPB S cell differentiation
ICDKHGKO_01202 8.4e-34 gerPA S Spore germination protein
ICDKHGKO_01203 1.6e-08 yisI S Spo0E like sporulation regulatory protein
ICDKHGKO_01204 2e-166 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
ICDKHGKO_01205 1.9e-59 yisL S UPF0344 protein
ICDKHGKO_01206 0.0 wprA O Belongs to the peptidase S8 family
ICDKHGKO_01207 3.1e-90 yisN S Protein of unknown function (DUF2777)
ICDKHGKO_01208 0.0 asnO 6.3.5.4 E Asparagine synthase
ICDKHGKO_01209 7e-117 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
ICDKHGKO_01210 1e-241 yisQ V Mate efflux family protein
ICDKHGKO_01211 8e-157 yisR K Transcriptional regulator
ICDKHGKO_01212 8.6e-142 purR K helix_turn _helix lactose operon repressor
ICDKHGKO_01213 4.4e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
ICDKHGKO_01214 5.2e-77 yisT S DinB family
ICDKHGKO_01215 1e-73 argO S Lysine exporter protein LysE YggA
ICDKHGKO_01216 1.5e-187 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ICDKHGKO_01217 2.4e-49 mcbG S Pentapeptide repeats (9 copies)
ICDKHGKO_01218 6e-76 yjcF S Acetyltransferase (GNAT) domain
ICDKHGKO_01219 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
ICDKHGKO_01220 1.9e-54 yajQ S Belongs to the UPF0234 family
ICDKHGKO_01221 3.9e-156 cvfB S protein conserved in bacteria
ICDKHGKO_01222 5e-147 yufN S ABC transporter substrate-binding protein PnrA-like
ICDKHGKO_01223 1.9e-175 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
ICDKHGKO_01224 1.8e-229 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
ICDKHGKO_01225 8.2e-154 yitS S protein conserved in bacteria
ICDKHGKO_01226 8.7e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
ICDKHGKO_01227 1e-78 ipi S Intracellular proteinase inhibitor
ICDKHGKO_01228 9.8e-26 S Protein of unknown function (DUF3813)
ICDKHGKO_01229 2e-07
ICDKHGKO_01230 4.4e-149 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
ICDKHGKO_01231 3.2e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
ICDKHGKO_01232 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
ICDKHGKO_01233 3.6e-70 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
ICDKHGKO_01234 5.1e-265 yitY C D-arabinono-1,4-lactone oxidase
ICDKHGKO_01235 9.4e-87 norB G Major Facilitator Superfamily
ICDKHGKO_01236 1.4e-192 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ICDKHGKO_01237 3.2e-220 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ICDKHGKO_01238 9.8e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
ICDKHGKO_01239 2.2e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
ICDKHGKO_01240 1.4e-195 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ICDKHGKO_01241 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
ICDKHGKO_01242 3.4e-172 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICDKHGKO_01243 2.1e-27 yjzC S YjzC-like protein
ICDKHGKO_01244 6.3e-22 yjzD S Protein of unknown function (DUF2929)
ICDKHGKO_01245 4.4e-132 yjaU I carboxylic ester hydrolase activity
ICDKHGKO_01246 5.5e-98 yjaV
ICDKHGKO_01247 2e-163 med S Transcriptional activator protein med
ICDKHGKO_01248 3.3e-26 comZ S ComZ
ICDKHGKO_01250 1.6e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICDKHGKO_01251 1.2e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ICDKHGKO_01252 2.1e-140 yjaZ O Zn-dependent protease
ICDKHGKO_01253 1.9e-178 appD P Belongs to the ABC transporter superfamily
ICDKHGKO_01254 1.7e-182 appF E Belongs to the ABC transporter superfamily
ICDKHGKO_01255 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
ICDKHGKO_01256 4.8e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICDKHGKO_01257 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICDKHGKO_01258 5.5e-146 yjbA S Belongs to the UPF0736 family
ICDKHGKO_01259 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
ICDKHGKO_01260 0.0 oppA E ABC transporter substrate-binding protein
ICDKHGKO_01261 7.8e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICDKHGKO_01262 6.5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICDKHGKO_01263 1.2e-199 oppD P Belongs to the ABC transporter superfamily
ICDKHGKO_01264 8.8e-170 oppF E Belongs to the ABC transporter superfamily
ICDKHGKO_01265 9.2e-220 S Putative glycosyl hydrolase domain
ICDKHGKO_01266 2.9e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICDKHGKO_01267 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ICDKHGKO_01268 1.1e-108 yjbE P Integral membrane protein TerC family
ICDKHGKO_01269 5e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
ICDKHGKO_01270 1.9e-201 yjbF S Competence protein
ICDKHGKO_01271 0.0 pepF E oligoendopeptidase F
ICDKHGKO_01272 5.8e-19
ICDKHGKO_01273 2.6e-166 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
ICDKHGKO_01274 5.9e-70 yjbI S Bacterial-like globin
ICDKHGKO_01275 7.9e-107 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
ICDKHGKO_01276 7.1e-93 yjbK S protein conserved in bacteria
ICDKHGKO_01277 5e-60 yjbL S Belongs to the UPF0738 family
ICDKHGKO_01278 1.9e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
ICDKHGKO_01279 3.9e-150 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICDKHGKO_01280 4.1e-156 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICDKHGKO_01281 3.8e-139 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
ICDKHGKO_01282 1.8e-307 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ICDKHGKO_01283 8.7e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ICDKHGKO_01284 4e-102 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
ICDKHGKO_01285 1.8e-201 thiO 1.4.3.19 E Glycine oxidase
ICDKHGKO_01286 7.5e-29 thiS H Thiamine biosynthesis
ICDKHGKO_01287 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
ICDKHGKO_01288 3e-179 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
ICDKHGKO_01289 2.6e-141 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICDKHGKO_01290 6.8e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
ICDKHGKO_01291 5.4e-72 yjbX S Spore coat protein
ICDKHGKO_01292 1.8e-80 cotZ S Spore coat protein
ICDKHGKO_01293 1.3e-92 cotY S Spore coat protein Z
ICDKHGKO_01294 1.3e-69 cotX S Spore Coat Protein X and V domain
ICDKHGKO_01295 1.4e-21 cotW
ICDKHGKO_01296 6.3e-53 cotV S Spore Coat Protein X and V domain
ICDKHGKO_01297 2.8e-55 yjcA S Protein of unknown function (DUF1360)
ICDKHGKO_01301 8.4e-38 spoVIF S Stage VI sporulation protein F
ICDKHGKO_01302 0.0 yjcD 3.6.4.12 L DNA helicase
ICDKHGKO_01303 6.2e-33
ICDKHGKO_01304 2.4e-125 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
ICDKHGKO_01305 1.7e-120 S ABC-2 type transporter
ICDKHGKO_01306 2.1e-129 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
ICDKHGKO_01307 8.8e-34 K SpoVT / AbrB like domain
ICDKHGKO_01308 2e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICDKHGKO_01309 7.8e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
ICDKHGKO_01310 1.2e-121 yjcH P COG2382 Enterochelin esterase and related enzymes
ICDKHGKO_01311 1.8e-209 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ICDKHGKO_01312 1.7e-213 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ICDKHGKO_01314 4.2e-81 L Belongs to the 'phage' integrase family
ICDKHGKO_01315 2.1e-27 K Helix-turn-helix XRE-family like proteins
ICDKHGKO_01317 2.9e-62
ICDKHGKO_01319 2.9e-141 S serine-type endopeptidase activity
ICDKHGKO_01323 1.1e-62
ICDKHGKO_01324 5.1e-227
ICDKHGKO_01328 7.6e-32
ICDKHGKO_01329 1e-48
ICDKHGKO_01330 4.2e-64
ICDKHGKO_01333 2.9e-23
ICDKHGKO_01335 2.4e-14 K Transcriptional regulator
ICDKHGKO_01336 9.6e-52 S Helix-turn-helix of insertion element transposase
ICDKHGKO_01337 1e-75 tnpR1 L Resolvase, N terminal domain
ICDKHGKO_01338 1e-296 S TIGRFAM Phage
ICDKHGKO_01339 4.7e-164 S Phage portal protein, SPP1 Gp6-like
ICDKHGKO_01340 2.2e-60 S Domain of unknown function (DUF4355)
ICDKHGKO_01341 2e-85 S P22 coat protein-protein 5 domain protein
ICDKHGKO_01343 4.7e-14 S Phage gp6-like head-tail connector protein
ICDKHGKO_01345 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
ICDKHGKO_01348 9e-22 S PIN domain
ICDKHGKO_01349 1.1e-10
ICDKHGKO_01350 5.2e-49 S Protein of unknown function (DUF1433)
ICDKHGKO_01351 3.7e-244 I Pfam Lipase (class 3)
ICDKHGKO_01352 2.7e-40
ICDKHGKO_01354 5.7e-22 K Cro/C1-type HTH DNA-binding domain
ICDKHGKO_01359 5.9e-55
ICDKHGKO_01360 2.6e-74 yobL S Bacterial EndoU nuclease
ICDKHGKO_01361 4.5e-31
ICDKHGKO_01362 7.1e-90 yokH G SMI1 / KNR4 family
ICDKHGKO_01363 5.5e-103 1.1.1.169 H 2-dehydropantoate 2-reductase
ICDKHGKO_01364 4.3e-22 yokK S SMI1 / KNR4 family
ICDKHGKO_01365 3e-62 H Acetyltransferase (GNAT) domain
ICDKHGKO_01366 3.7e-25
ICDKHGKO_01367 8.5e-203 2.7.7.49 L PFAM Reverse transcriptase (RNA-dependent DNA polymerase)
ICDKHGKO_01368 1.1e-197 K Psort location Cytoplasmic, score
ICDKHGKO_01369 1.5e-101 K Psort location Cytoplasmic, score
ICDKHGKO_01370 7.7e-189 K Psort location Cytoplasmic, score
ICDKHGKO_01372 3.5e-36 S YolD-like protein
ICDKHGKO_01373 5.8e-46 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICDKHGKO_01374 2.2e-28 S Bacillus cereus group antimicrobial protein
ICDKHGKO_01379 1.5e-16 N Kelch motif
ICDKHGKO_01381 2e-153 bla 3.5.2.6 V beta-lactamase
ICDKHGKO_01382 3e-44 yjcS S Antibiotic biosynthesis monooxygenase
ICDKHGKO_01383 3e-238 yfjF EGP Belongs to the major facilitator superfamily
ICDKHGKO_01384 2.2e-76 napB K helix_turn_helix multiple antibiotic resistance protein
ICDKHGKO_01385 1.8e-217 ganA 3.2.1.89 G arabinogalactan
ICDKHGKO_01386 3.7e-299 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICDKHGKO_01387 3.4e-49 lacF 2.7.1.207 G phosphotransferase system
ICDKHGKO_01388 1.6e-279 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
ICDKHGKO_01389 3.7e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
ICDKHGKO_01390 5.8e-118 5.4.2.6 S Haloacid dehalogenase-like hydrolase
ICDKHGKO_01391 7.6e-34
ICDKHGKO_01392 4.5e-52 K helix_turn_helix multiple antibiotic resistance protein
ICDKHGKO_01393 2.2e-103 yhiD S MgtC SapB transporter
ICDKHGKO_01395 5.4e-20 yjfB S Putative motility protein
ICDKHGKO_01396 5.9e-62 T PhoQ Sensor
ICDKHGKO_01397 2.9e-94 yjgB S Domain of unknown function (DUF4309)
ICDKHGKO_01398 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
ICDKHGKO_01399 3.8e-118 ybbM S transport system, permease component
ICDKHGKO_01400 4.7e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
ICDKHGKO_01401 6.8e-29
ICDKHGKO_01402 1.8e-215 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
ICDKHGKO_01403 2.7e-214 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
ICDKHGKO_01404 9.2e-69 yjgD S Protein of unknown function (DUF1641)
ICDKHGKO_01405 2.7e-152 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
ICDKHGKO_01406 6.5e-33 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
ICDKHGKO_01407 5.9e-172 yjlA EG Putative multidrug resistance efflux transporter
ICDKHGKO_01408 7.3e-86 yjlB S Cupin domain
ICDKHGKO_01409 7e-66 yjlC S Protein of unknown function (DUF1641)
ICDKHGKO_01410 3.2e-217 yjlD 1.6.99.3 C NADH dehydrogenase
ICDKHGKO_01411 2e-65 uxaC 5.3.1.12 G glucuronate isomerase
ICDKHGKO_01412 5.4e-181 exuR K transcriptional
ICDKHGKO_01413 9.7e-161 uxaA 4.2.1.7, 4.4.1.24 G Altronate
ICDKHGKO_01414 5.2e-87 T Transcriptional regulatory protein, C terminal
ICDKHGKO_01415 1.4e-128 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
ICDKHGKO_01417 6.9e-128 MA20_18170 S membrane transporter protein
ICDKHGKO_01418 4.9e-76 yjoA S DinB family
ICDKHGKO_01419 3.2e-214 S response regulator aspartate phosphatase
ICDKHGKO_01421 3.1e-162 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ICDKHGKO_01422 6.8e-60 yjqA S Bacterial PH domain
ICDKHGKO_01423 4.8e-100 yjqB S phage-related replication protein
ICDKHGKO_01424 1.5e-106 xkdA E IrrE N-terminal-like domain
ICDKHGKO_01425 2.6e-55 xre K Helix-turn-helix XRE-family like proteins
ICDKHGKO_01427 3.2e-144 xkdC L Bacterial dnaA protein
ICDKHGKO_01430 4.5e-10 yqaO S Phage-like element PBSX protein XtrA
ICDKHGKO_01431 8.5e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
ICDKHGKO_01432 1.5e-109 xtmA L phage terminase small subunit
ICDKHGKO_01433 1.6e-209 xtmB S phage terminase, large subunit
ICDKHGKO_01434 2.5e-240 yqbA S portal protein
ICDKHGKO_01435 7.5e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
ICDKHGKO_01436 3e-157 xkdG S Phage capsid family
ICDKHGKO_01437 3.3e-40 yqbH S Domain of unknown function (DUF3599)
ICDKHGKO_01438 4.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
ICDKHGKO_01439 5.8e-58 xkdJ
ICDKHGKO_01440 6.3e-15
ICDKHGKO_01441 3.2e-224 xkdK S Phage tail sheath C-terminal domain
ICDKHGKO_01442 2e-74 xkdM S Phage tail tube protein
ICDKHGKO_01443 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
ICDKHGKO_01444 3.4e-19
ICDKHGKO_01445 1.6e-191 xkdO L Transglycosylase SLT domain
ICDKHGKO_01446 1.3e-111 xkdP S Lysin motif
ICDKHGKO_01447 2.9e-163 xkdQ 3.2.1.96 G NLP P60 protein
ICDKHGKO_01448 8.5e-33 xkdR S Protein of unknown function (DUF2577)
ICDKHGKO_01449 2.7e-57 xkdS S Protein of unknown function (DUF2634)
ICDKHGKO_01450 1.5e-162 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
ICDKHGKO_01451 4.2e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
ICDKHGKO_01452 6.1e-26
ICDKHGKO_01453 7.9e-160
ICDKHGKO_01455 6.8e-27 xkdX
ICDKHGKO_01456 2.5e-130 xepA
ICDKHGKO_01457 7.4e-37 xhlA S Haemolysin XhlA
ICDKHGKO_01458 4.3e-37 xhlB S SPP1 phage holin
ICDKHGKO_01459 1.5e-143 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ICDKHGKO_01460 8.7e-23 spoIISB S Stage II sporulation protein SB
ICDKHGKO_01461 1.7e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
ICDKHGKO_01462 2.4e-173 pit P phosphate transporter
ICDKHGKO_01463 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
ICDKHGKO_01464 1.4e-240 steT E amino acid
ICDKHGKO_01465 5.3e-178 mhqA E COG0346 Lactoylglutathione lyase and related lyases
ICDKHGKO_01466 5.2e-298 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICDKHGKO_01467 1.2e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ICDKHGKO_01469 5e-198 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICDKHGKO_01470 2.3e-263 yubD P Major Facilitator Superfamily
ICDKHGKO_01471 3.6e-154 dppA E D-aminopeptidase
ICDKHGKO_01472 3.5e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICDKHGKO_01473 5.3e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ICDKHGKO_01474 3e-182 dppD P Belongs to the ABC transporter superfamily
ICDKHGKO_01475 1.3e-309 dppE E ABC transporter substrate-binding protein
ICDKHGKO_01476 1.9e-172 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
ICDKHGKO_01477 1.1e-190 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
ICDKHGKO_01478 2.4e-156 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
ICDKHGKO_01479 4.4e-180 ykfD E Belongs to the ABC transporter superfamily
ICDKHGKO_01480 1.4e-200 pgl 3.1.1.31 G 6-phosphogluconolactonase
ICDKHGKO_01481 1.5e-131 ykgA E Amidinotransferase
ICDKHGKO_01482 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
ICDKHGKO_01483 4.4e-92 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ICDKHGKO_01484 1.2e-48 ykkC P Multidrug resistance protein
ICDKHGKO_01485 1e-48 ykkD P Multidrug resistance protein
ICDKHGKO_01486 4.4e-166 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
ICDKHGKO_01487 4.4e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICDKHGKO_01488 3.3e-220 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ICDKHGKO_01489 4.1e-69 ohrA O Organic hydroperoxide resistance protein
ICDKHGKO_01490 7.5e-78 ohrR K COG1846 Transcriptional regulators
ICDKHGKO_01491 7.9e-70 ohrB O Organic hydroperoxide resistance protein
ICDKHGKO_01492 2.9e-51 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICDKHGKO_01494 6e-205 M Glycosyl transferase family 2
ICDKHGKO_01495 1.6e-106 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
ICDKHGKO_01496 4e-207 hcaT 1.5.1.2 EGP Major facilitator Superfamily
ICDKHGKO_01497 9.9e-118 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
ICDKHGKO_01498 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ICDKHGKO_01499 6.8e-173 isp O Belongs to the peptidase S8 family
ICDKHGKO_01500 7.8e-141 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ICDKHGKO_01501 7.1e-125 ykoC P Cobalt transport protein
ICDKHGKO_01502 8.6e-277 P ABC transporter, ATP-binding protein
ICDKHGKO_01503 9.3e-96 ykoE S ABC-type cobalt transport system, permease component
ICDKHGKO_01504 1.6e-238 ydhD M Glycosyl hydrolase
ICDKHGKO_01506 3e-235 mgtE P Acts as a magnesium transporter
ICDKHGKO_01507 1.6e-52 tnrA K transcriptional
ICDKHGKO_01508 1.9e-16
ICDKHGKO_01509 5.9e-25 ykoL
ICDKHGKO_01510 4.2e-80 ykoM K transcriptional
ICDKHGKO_01511 4.1e-98 ykoP G polysaccharide deacetylase
ICDKHGKO_01512 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
ICDKHGKO_01513 2.8e-149 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ICDKHGKO_01514 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
ICDKHGKO_01515 4.4e-95 ykoX S membrane-associated protein
ICDKHGKO_01516 5.4e-128 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
ICDKHGKO_01517 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICDKHGKO_01518 4.5e-118 rsgI S Anti-sigma factor N-terminus
ICDKHGKO_01519 9.6e-26 sspD S small acid-soluble spore protein
ICDKHGKO_01520 9.5e-124 ykrK S Domain of unknown function (DUF1836)
ICDKHGKO_01521 3.9e-154 htpX O Belongs to the peptidase M48B family
ICDKHGKO_01522 6.1e-236 ktrB P COG0168 Trk-type K transport systems, membrane components
ICDKHGKO_01523 3e-111 ydfR S Protein of unknown function (DUF421)
ICDKHGKO_01524 1.2e-19 ykzE
ICDKHGKO_01525 3.8e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
ICDKHGKO_01526 0.0 kinE 2.7.13.3 T Histidine kinase
ICDKHGKO_01527 5.4e-81 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICDKHGKO_01529 1e-190 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ICDKHGKO_01530 1.6e-219 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ICDKHGKO_01531 7.3e-138 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
ICDKHGKO_01532 5.2e-223 mtnE 2.6.1.83 E Aminotransferase
ICDKHGKO_01533 6.9e-223 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
ICDKHGKO_01534 1.6e-131 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ICDKHGKO_01535 1.2e-109 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
ICDKHGKO_01536 3.6e-91 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ICDKHGKO_01537 4e-11 S Spo0E like sporulation regulatory protein
ICDKHGKO_01538 1e-268 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
ICDKHGKO_01539 3.2e-77 ykvE K transcriptional
ICDKHGKO_01540 1.7e-121 motB N Flagellar motor protein
ICDKHGKO_01541 2.5e-136 motA N flagellar motor
ICDKHGKO_01542 0.0 clpE O Belongs to the ClpA ClpB family
ICDKHGKO_01543 6.4e-177 ykvI S membrane
ICDKHGKO_01544 4.9e-13
ICDKHGKO_01545 2.1e-145
ICDKHGKO_01546 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ICDKHGKO_01547 2.9e-78 queD 4.1.2.50, 4.2.3.12 H synthase
ICDKHGKO_01548 7.8e-137 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
ICDKHGKO_01549 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICDKHGKO_01550 1.8e-41 ykvR S Protein of unknown function (DUF3219)
ICDKHGKO_01551 1.7e-24 ykvS S protein conserved in bacteria
ICDKHGKO_01552 2.3e-27
ICDKHGKO_01553 1.1e-104 ykvT 3.5.1.28 M Cell Wall Hydrolase
ICDKHGKO_01554 4.6e-236 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICDKHGKO_01555 8.3e-82 stoA CO thiol-disulfide
ICDKHGKO_01556 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
ICDKHGKO_01557 5e-204 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
ICDKHGKO_01559 1.9e-170 ykvZ 5.1.1.1 K Transcriptional regulator
ICDKHGKO_01560 8.1e-154 glcT K antiterminator
ICDKHGKO_01561 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ICDKHGKO_01562 2.1e-39 ptsH G phosphocarrier protein HPr
ICDKHGKO_01563 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICDKHGKO_01564 6.7e-37 splA S Transcriptional regulator
ICDKHGKO_01565 1.8e-192 splB 4.1.99.14 L Spore photoproduct lyase
ICDKHGKO_01566 1.1e-252 mcpC NT chemotaxis protein
ICDKHGKO_01567 2.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
ICDKHGKO_01568 1.6e-48
ICDKHGKO_01569 2.2e-113 ykwD J protein with SCP PR1 domains
ICDKHGKO_01570 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
ICDKHGKO_01571 4.1e-288 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
ICDKHGKO_01572 5.7e-214 patA 2.6.1.1 E Aminotransferase
ICDKHGKO_01573 1.4e-09
ICDKHGKO_01574 2.2e-165 cheV 2.7.13.3 T Chemotaxis protein CheV
ICDKHGKO_01575 3.2e-83 ykyB S YkyB-like protein
ICDKHGKO_01576 9.9e-236 ykuC EGP Major facilitator Superfamily
ICDKHGKO_01577 5.1e-87 ykuD S protein conserved in bacteria
ICDKHGKO_01578 7.5e-147 ykuE S Metallophosphoesterase
ICDKHGKO_01579 5.6e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICDKHGKO_01581 2.4e-231 ykuI T Diguanylate phosphodiesterase
ICDKHGKO_01582 2e-36 ykuJ S protein conserved in bacteria
ICDKHGKO_01583 1.7e-90 ykuK S Ribonuclease H-like
ICDKHGKO_01584 7.3e-26 ykzF S Antirepressor AbbA
ICDKHGKO_01585 8.8e-75 ykuL S CBS domain
ICDKHGKO_01586 2.3e-167 ccpC K Transcriptional regulator
ICDKHGKO_01587 2.4e-86 fld C Flavodoxin
ICDKHGKO_01588 8.6e-162 ykuO
ICDKHGKO_01589 1.3e-73 fld C Flavodoxin
ICDKHGKO_01590 4.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ICDKHGKO_01591 6.7e-212 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ICDKHGKO_01592 1.8e-37 ykuS S Belongs to the UPF0180 family
ICDKHGKO_01593 1.6e-138 ykuT M Mechanosensitive ion channel
ICDKHGKO_01595 5.5e-72 ykuV CO thiol-disulfide
ICDKHGKO_01597 3.8e-97 rok K Repressor of ComK
ICDKHGKO_01598 1.2e-145 yknT
ICDKHGKO_01599 2.2e-100 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
ICDKHGKO_01600 4.1e-184 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
ICDKHGKO_01601 1.5e-239 moeA 2.10.1.1 H molybdopterin
ICDKHGKO_01602 1.7e-85 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
ICDKHGKO_01603 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
ICDKHGKO_01604 4.1e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ICDKHGKO_01605 7.3e-100 yknW S Yip1 domain
ICDKHGKO_01606 9.9e-155 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICDKHGKO_01607 5.1e-122 macB V ABC transporter, ATP-binding protein
ICDKHGKO_01608 4e-207 yknZ V ABC transporter (permease)
ICDKHGKO_01609 4.3e-130 fruR K Transcriptional regulator
ICDKHGKO_01610 7.1e-164 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
ICDKHGKO_01611 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
ICDKHGKO_01612 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
ICDKHGKO_01613 6.4e-36 ykoA
ICDKHGKO_01614 5.5e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ICDKHGKO_01615 1.4e-114 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICDKHGKO_01616 1.2e-22 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICDKHGKO_01617 9.5e-236 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
ICDKHGKO_01618 1.1e-12 S Uncharacterized protein YkpC
ICDKHGKO_01619 7.7e-183 mreB D Rod-share determining protein MreBH
ICDKHGKO_01620 1e-44 abrB K of stationary sporulation gene expression
ICDKHGKO_01621 9.1e-237 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
ICDKHGKO_01622 1.6e-146 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
ICDKHGKO_01623 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
ICDKHGKO_01624 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ICDKHGKO_01625 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICDKHGKO_01626 5.3e-30 ykzG S Belongs to the UPF0356 family
ICDKHGKO_01627 2.5e-141 ykrA S hydrolases of the HAD superfamily
ICDKHGKO_01628 1.6e-97 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ICDKHGKO_01630 3e-66 recN L Putative cell-wall binding lipoprotein
ICDKHGKO_01631 3.8e-183 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ICDKHGKO_01632 1.2e-177 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ICDKHGKO_01633 2.1e-225 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICDKHGKO_01634 2.7e-242 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ICDKHGKO_01635 6.1e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
ICDKHGKO_01636 1.4e-126 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
ICDKHGKO_01637 5.2e-273 speA 4.1.1.19 E Arginine
ICDKHGKO_01638 5.9e-42 yktA S Belongs to the UPF0223 family
ICDKHGKO_01639 5.4e-118 yktB S Belongs to the UPF0637 family
ICDKHGKO_01640 6.3e-24 ykzI
ICDKHGKO_01641 5.1e-150 suhB 3.1.3.25 G Inositol monophosphatase
ICDKHGKO_01642 1.6e-70 ykzC S Acetyltransferase (GNAT) family
ICDKHGKO_01643 3e-287 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
ICDKHGKO_01644 5.6e-26 ylaA
ICDKHGKO_01645 1.7e-13 sigC S Putative zinc-finger
ICDKHGKO_01646 2e-37 ylaE
ICDKHGKO_01647 6.7e-24 S Family of unknown function (DUF5325)
ICDKHGKO_01648 0.0 typA T GTP-binding protein TypA
ICDKHGKO_01649 6.6e-48 ylaH S YlaH-like protein
ICDKHGKO_01650 1.5e-32 ylaI S protein conserved in bacteria
ICDKHGKO_01651 6.1e-98 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ICDKHGKO_01652 7.8e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
ICDKHGKO_01653 2.2e-79 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ICDKHGKO_01654 2e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
ICDKHGKO_01655 8.7e-44 ylaN S Belongs to the UPF0358 family
ICDKHGKO_01656 1.1e-209 ftsW D Belongs to the SEDS family
ICDKHGKO_01657 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ICDKHGKO_01658 2.5e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
ICDKHGKO_01659 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
ICDKHGKO_01660 8.9e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
ICDKHGKO_01661 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ICDKHGKO_01662 1.5e-109 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
ICDKHGKO_01663 6e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
ICDKHGKO_01664 1.9e-161 ctaG S cytochrome c oxidase
ICDKHGKO_01665 4.6e-58 ylbA S YugN-like family
ICDKHGKO_01666 1.2e-71 ylbB T COG0517 FOG CBS domain
ICDKHGKO_01667 6.4e-193 ylbC S protein with SCP PR1 domains
ICDKHGKO_01668 1.5e-52 ylbD S Putative coat protein
ICDKHGKO_01669 8.8e-37 ylbE S YlbE-like protein
ICDKHGKO_01670 2.5e-69 ylbF S Belongs to the UPF0342 family
ICDKHGKO_01671 1e-41 ylbG S UPF0298 protein
ICDKHGKO_01672 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
ICDKHGKO_01673 2.1e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ICDKHGKO_01674 3e-210 ylbJ S Sporulation integral membrane protein YlbJ
ICDKHGKO_01675 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
ICDKHGKO_01676 2.6e-183 ylbL T Belongs to the peptidase S16 family
ICDKHGKO_01677 2.2e-220 ylbM S Belongs to the UPF0348 family
ICDKHGKO_01678 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
ICDKHGKO_01679 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ICDKHGKO_01680 5e-70 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
ICDKHGKO_01681 5.8e-88 ylbP K n-acetyltransferase
ICDKHGKO_01682 5e-149 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ICDKHGKO_01683 1.1e-300 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ICDKHGKO_01684 1.2e-77 mraZ K Belongs to the MraZ family
ICDKHGKO_01685 5.6e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ICDKHGKO_01686 2.4e-51 ftsL D Essential cell division protein
ICDKHGKO_01687 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
ICDKHGKO_01688 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
ICDKHGKO_01689 3.7e-279 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICDKHGKO_01690 1.4e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICDKHGKO_01691 6.7e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICDKHGKO_01692 2.2e-185 spoVE D Belongs to the SEDS family
ICDKHGKO_01693 3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ICDKHGKO_01694 1.3e-165 murB 1.3.1.98 M cell wall formation
ICDKHGKO_01695 1.3e-126 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ICDKHGKO_01696 1.7e-227 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ICDKHGKO_01697 7.5e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ICDKHGKO_01698 0.0 bpr O COG1404 Subtilisin-like serine proteases
ICDKHGKO_01699 7.8e-158 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
ICDKHGKO_01700 1.2e-116 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICDKHGKO_01701 3.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICDKHGKO_01702 7.9e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
ICDKHGKO_01703 7e-242 argE 3.5.1.16 E Acetylornithine deacetylase
ICDKHGKO_01704 2.2e-38 ylmC S sporulation protein
ICDKHGKO_01705 5.2e-153 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
ICDKHGKO_01706 4.1e-119 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ICDKHGKO_01707 5.7e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ICDKHGKO_01708 5.2e-41 yggT S membrane
ICDKHGKO_01709 6.3e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
ICDKHGKO_01710 8.9e-68 divIVA D Cell division initiation protein
ICDKHGKO_01711 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ICDKHGKO_01712 3.8e-63 dksA T COG1734 DnaK suppressor protein
ICDKHGKO_01713 1.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ICDKHGKO_01714 1.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ICDKHGKO_01715 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ICDKHGKO_01716 1.1e-229 pyrP F Xanthine uracil
ICDKHGKO_01717 1.7e-160 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ICDKHGKO_01718 2.2e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ICDKHGKO_01719 3.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ICDKHGKO_01720 0.0 carB 6.3.5.5 F Belongs to the CarB family
ICDKHGKO_01721 1.1e-138 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
ICDKHGKO_01722 1.6e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ICDKHGKO_01723 1.7e-123 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ICDKHGKO_01724 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICDKHGKO_01725 6.1e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
ICDKHGKO_01726 8e-175 cysP P phosphate transporter
ICDKHGKO_01727 3.6e-221 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
ICDKHGKO_01728 2.1e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
ICDKHGKO_01729 1.4e-139 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
ICDKHGKO_01730 3.2e-136 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
ICDKHGKO_01731 4.3e-75 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
ICDKHGKO_01732 1.3e-266 amyA 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
ICDKHGKO_01733 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
ICDKHGKO_01734 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
ICDKHGKO_01735 2.3e-151 yloC S stress-induced protein
ICDKHGKO_01736 1.5e-40 ylzA S Belongs to the UPF0296 family
ICDKHGKO_01737 8.9e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
ICDKHGKO_01738 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ICDKHGKO_01739 3.5e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ICDKHGKO_01740 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICDKHGKO_01741 4.7e-82 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ICDKHGKO_01742 6.4e-168 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ICDKHGKO_01743 3.2e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICDKHGKO_01744 1.7e-204 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ICDKHGKO_01745 7.1e-133 stp 3.1.3.16 T phosphatase
ICDKHGKO_01746 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
ICDKHGKO_01747 3.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ICDKHGKO_01748 2.2e-114 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
ICDKHGKO_01749 1.8e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
ICDKHGKO_01750 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
ICDKHGKO_01751 6.1e-58 asp S protein conserved in bacteria
ICDKHGKO_01752 1.3e-299 yloV S kinase related to dihydroxyacetone kinase
ICDKHGKO_01753 4.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
ICDKHGKO_01754 3.9e-154 sdaAA 4.3.1.17 E L-serine dehydratase
ICDKHGKO_01755 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICDKHGKO_01756 2.2e-91 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
ICDKHGKO_01757 2.3e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ICDKHGKO_01758 1.9e-167 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
ICDKHGKO_01759 1.1e-127 IQ reductase
ICDKHGKO_01760 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ICDKHGKO_01761 7.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ICDKHGKO_01762 0.0 smc D Required for chromosome condensation and partitioning
ICDKHGKO_01763 5.9e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ICDKHGKO_01764 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ICDKHGKO_01765 9e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICDKHGKO_01766 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ICDKHGKO_01767 1.7e-35 ylqC S Belongs to the UPF0109 family
ICDKHGKO_01768 1.1e-60 ylqD S YlqD protein
ICDKHGKO_01769 1.4e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICDKHGKO_01770 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ICDKHGKO_01771 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ICDKHGKO_01772 5.5e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ICDKHGKO_01773 5.5e-125 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICDKHGKO_01774 1.4e-266 ylqG
ICDKHGKO_01775 1.6e-42 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
ICDKHGKO_01776 2.6e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
ICDKHGKO_01777 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ICDKHGKO_01778 1.7e-162 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
ICDKHGKO_01779 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ICDKHGKO_01780 5.3e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ICDKHGKO_01781 3.3e-169 xerC L tyrosine recombinase XerC
ICDKHGKO_01782 2.2e-91 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ICDKHGKO_01783 1.4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ICDKHGKO_01784 2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ICDKHGKO_01785 7.8e-51 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
ICDKHGKO_01786 9.9e-74 flgC N Belongs to the flagella basal body rod proteins family
ICDKHGKO_01787 2.5e-31 fliE N Flagellar hook-basal body
ICDKHGKO_01788 2.7e-251 fliF N The M ring may be actively involved in energy transduction
ICDKHGKO_01789 1.7e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
ICDKHGKO_01790 1.4e-85 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
ICDKHGKO_01791 2.7e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
ICDKHGKO_01792 4.5e-71 fliJ N Flagellar biosynthesis chaperone
ICDKHGKO_01793 1.2e-37 ylxF S MgtE intracellular N domain
ICDKHGKO_01794 5.5e-189 fliK N Flagellar hook-length control protein
ICDKHGKO_01795 2.7e-68 flgD N Flagellar basal body rod modification protein
ICDKHGKO_01796 5.4e-136 flgG N Flagellar basal body rod
ICDKHGKO_01797 5.1e-56 fliL N Controls the rotational direction of flagella during chemotaxis
ICDKHGKO_01798 7.8e-180 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
ICDKHGKO_01799 3.8e-175 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ICDKHGKO_01800 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
ICDKHGKO_01801 3.3e-110 fliZ N Flagellar biosynthesis protein, FliO
ICDKHGKO_01802 3.7e-109 fliP N Plays a role in the flagellum-specific transport system
ICDKHGKO_01803 7.5e-37 fliQ N Role in flagellar biosynthesis
ICDKHGKO_01804 3.2e-128 fliR N Flagellar biosynthetic protein FliR
ICDKHGKO_01805 1.1e-187 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ICDKHGKO_01806 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ICDKHGKO_01807 2.9e-156 flhF N Flagellar biosynthesis regulator FlhF
ICDKHGKO_01808 4.3e-153 flhG D Belongs to the ParA family
ICDKHGKO_01809 1.2e-186 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
ICDKHGKO_01810 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
ICDKHGKO_01811 2.5e-80 cheW NT COG0835 Chemotaxis signal transduction protein
ICDKHGKO_01812 7e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
ICDKHGKO_01813 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
ICDKHGKO_01814 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICDKHGKO_01815 1.7e-47 ylxL
ICDKHGKO_01816 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
ICDKHGKO_01817 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ICDKHGKO_01818 1.6e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ICDKHGKO_01819 2.1e-89 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ICDKHGKO_01820 1.3e-142 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICDKHGKO_01821 8.4e-137 cdsA 2.7.7.41 S Belongs to the CDS family
ICDKHGKO_01822 2.3e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
ICDKHGKO_01823 4.2e-231 rasP M zinc metalloprotease
ICDKHGKO_01824 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ICDKHGKO_01825 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ICDKHGKO_01826 1.9e-80 rimP S Required for maturation of 30S ribosomal subunits
ICDKHGKO_01827 3.5e-205 nusA K Participates in both transcription termination and antitermination
ICDKHGKO_01828 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
ICDKHGKO_01829 1.8e-47 ylxQ J ribosomal protein
ICDKHGKO_01830 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ICDKHGKO_01831 8.6e-44 ylxP S protein conserved in bacteria
ICDKHGKO_01832 3.7e-51 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ICDKHGKO_01833 2.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ICDKHGKO_01834 1.4e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
ICDKHGKO_01835 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICDKHGKO_01836 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
ICDKHGKO_01837 1.4e-178 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
ICDKHGKO_01838 2e-233 pepR S Belongs to the peptidase M16 family
ICDKHGKO_01839 2.6e-42 ymxH S YlmC YmxH family
ICDKHGKO_01840 9.8e-158 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
ICDKHGKO_01841 4.3e-101 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
ICDKHGKO_01842 1.1e-189 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICDKHGKO_01843 2.2e-216 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
ICDKHGKO_01844 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICDKHGKO_01845 4.7e-302 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ICDKHGKO_01846 6.6e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
ICDKHGKO_01847 2.6e-29 S YlzJ-like protein
ICDKHGKO_01848 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
ICDKHGKO_01849 2e-129 ymfC K Transcriptional regulator
ICDKHGKO_01850 6.2e-225 ymfD EGP Major facilitator Superfamily
ICDKHGKO_01851 5.8e-74 K helix_turn_helix multiple antibiotic resistance protein
ICDKHGKO_01852 0.0 ydgH S drug exporters of the RND superfamily
ICDKHGKO_01853 7e-234 ymfF S Peptidase M16
ICDKHGKO_01854 7.3e-239 ymfH S zinc protease
ICDKHGKO_01855 8.1e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
ICDKHGKO_01856 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
ICDKHGKO_01857 5.1e-142 ymfK S Protein of unknown function (DUF3388)
ICDKHGKO_01858 6.4e-117 ymfM S protein conserved in bacteria
ICDKHGKO_01859 4.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICDKHGKO_01860 2.1e-230 cinA 3.5.1.42 S Belongs to the CinA family
ICDKHGKO_01861 7.6e-186 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICDKHGKO_01862 2.4e-180 pbpX V Beta-lactamase
ICDKHGKO_01863 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
ICDKHGKO_01864 1.9e-152 ymdB S protein conserved in bacteria
ICDKHGKO_01865 1.2e-36 spoVS S Stage V sporulation protein S
ICDKHGKO_01866 3.1e-195 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
ICDKHGKO_01867 7e-212 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
ICDKHGKO_01868 4.2e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ICDKHGKO_01869 1.2e-65 ymcA 3.6.3.21 S Belongs to the UPF0342 family
ICDKHGKO_01870 2.1e-86 cotE S Spore coat protein
ICDKHGKO_01871 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ICDKHGKO_01872 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ICDKHGKO_01873 2.9e-125 pksB 3.1.2.6 S Polyketide biosynthesis
ICDKHGKO_01874 8.6e-159 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
ICDKHGKO_01875 2.5e-148 pksD Q Acyl transferase domain
ICDKHGKO_01876 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
ICDKHGKO_01877 8.5e-35 acpK IQ Phosphopantetheine attachment site
ICDKHGKO_01878 1.5e-241 pksG 2.3.3.10 I synthase
ICDKHGKO_01879 8.8e-139 pksH 4.2.1.18 I enoyl-CoA hydratase
ICDKHGKO_01880 6.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
ICDKHGKO_01881 0.0 rhiB IQ polyketide synthase
ICDKHGKO_01882 0.0 Q Polyketide synthase of type I
ICDKHGKO_01883 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
ICDKHGKO_01884 0.0 dhbF IQ polyketide synthase
ICDKHGKO_01885 0.0 pks13 HQ Beta-ketoacyl synthase
ICDKHGKO_01886 1.4e-223 cypA C Cytochrome P450
ICDKHGKO_01887 5.2e-72 nucB M Deoxyribonuclease NucA/NucB
ICDKHGKO_01888 3.4e-116 yoaK S Membrane
ICDKHGKO_01889 1.6e-61 ymzB
ICDKHGKO_01890 3.1e-248 aprX O Belongs to the peptidase S8 family
ICDKHGKO_01892 1e-117 ymaC S Replication protein
ICDKHGKO_01893 1.4e-75 ymaD O redox protein, regulator of disulfide bond formation
ICDKHGKO_01894 9.8e-53 ebrB P Small Multidrug Resistance protein
ICDKHGKO_01895 2.5e-47 ebrA P Small Multidrug Resistance protein
ICDKHGKO_01897 2.8e-43 ymaF S YmaF family
ICDKHGKO_01898 6.7e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICDKHGKO_01899 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
ICDKHGKO_01900 2.6e-40
ICDKHGKO_01901 7.9e-21 ymzA
ICDKHGKO_01902 2.3e-58 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
ICDKHGKO_01903 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICDKHGKO_01904 2.6e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICDKHGKO_01905 1.3e-103 ymaB S MutT family
ICDKHGKO_01907 4.1e-88 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ICDKHGKO_01908 8.6e-176 spoVK O stage V sporulation protein K
ICDKHGKO_01909 3.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICDKHGKO_01910 5e-240 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
ICDKHGKO_01911 8.8e-66 glnR K transcriptional
ICDKHGKO_01912 1.2e-260 glnA 6.3.1.2 E glutamine synthetase
ICDKHGKO_01913 5.7e-134 L Belongs to the 'phage' integrase family
ICDKHGKO_01914 3.5e-53 1.15.1.2 E Pfam:DUF955
ICDKHGKO_01915 3.6e-11 K Helix-turn-helix XRE-family like proteins
ICDKHGKO_01917 7.3e-53 S Phage regulatory protein Rha (Phage_pRha)
ICDKHGKO_01918 4.7e-19
ICDKHGKO_01921 5.3e-25
ICDKHGKO_01922 9.4e-12
ICDKHGKO_01923 5.6e-161 L Protein of unknown function (DUF2800)
ICDKHGKO_01924 7.8e-84 S Protein of unknown function (DUF2815)
ICDKHGKO_01925 4.3e-23
ICDKHGKO_01926 1.4e-297 2.7.7.7 L DNA polymerase A domain
ICDKHGKO_01928 5.3e-104 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
ICDKHGKO_01929 1.4e-11 S Protein of unknown function (DUF2815)
ICDKHGKO_01930 0.0 L Virulence-associated protein E
ICDKHGKO_01931 3e-19 S VRR_NUC
ICDKHGKO_01932 2e-226 KL SNF2 family N-terminal domain
ICDKHGKO_01933 1.7e-47
ICDKHGKO_01935 2.1e-56 terS L Terminase, small subunit
ICDKHGKO_01936 8.4e-150 terL S Terminase
ICDKHGKO_01938 1.4e-175 S portal protein
ICDKHGKO_01939 1.2e-74 pi136 S Caudovirus prohead serine protease
ICDKHGKO_01940 3.3e-124 S capsid protein
ICDKHGKO_01941 6.1e-18
ICDKHGKO_01942 1.7e-21 S Phage gp6-like head-tail connector protein
ICDKHGKO_01943 6.3e-30 S Phage head-tail joining protein
ICDKHGKO_01944 1.8e-31 S Bacteriophage HK97-gp10, putative tail-component
ICDKHGKO_01945 4.8e-08
ICDKHGKO_01946 1.4e-32 S Phage tail tube protein
ICDKHGKO_01948 0.0 D Phage tail tape measure protein
ICDKHGKO_01949 2.1e-117 S Phage tail protein
ICDKHGKO_01950 6.3e-262 NU Prophage endopeptidase tail
ICDKHGKO_01951 0.0 M Pectate lyase superfamily protein
ICDKHGKO_01952 8.1e-141 S Domain of unknown function (DUF2479)
ICDKHGKO_01955 6.9e-61 S Pfam:Phage_holin_4_1
ICDKHGKO_01956 1.5e-122 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ICDKHGKO_01957 1.6e-29 S Domain of unknown function (DUF4917)
ICDKHGKO_01958 3.2e-08
ICDKHGKO_01960 1.3e-12
ICDKHGKO_01961 3.9e-116 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
ICDKHGKO_01962 8.6e-213 cypA C Cytochrome P450
ICDKHGKO_01963 5.1e-246 xynT G MFS/sugar transport protein
ICDKHGKO_01964 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
ICDKHGKO_01965 6.2e-103 xylR GK ROK family
ICDKHGKO_01966 9.5e-73 xylR GK ROK family
ICDKHGKO_01967 2.2e-254 xylA 5.3.1.5 G Belongs to the xylose isomerase family
ICDKHGKO_01968 1.8e-273 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
ICDKHGKO_01969 1.5e-116 3.2.1.8 G Glycosyl hydrolases family 11
ICDKHGKO_01970 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
ICDKHGKO_01971 1.3e-88 K Transcriptional regulator, TetR family
ICDKHGKO_01972 2.2e-177 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
ICDKHGKO_01974 8.7e-196 S aspartate phosphatase
ICDKHGKO_01976 0.0 L Transposase and inactivated derivatives, TnpA family
ICDKHGKO_01977 7.1e-85 L resolvase
ICDKHGKO_01978 1.3e-78
ICDKHGKO_01980 6e-26 S Protein of unknown function (DUF1657)
ICDKHGKO_01981 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ICDKHGKO_01982 2.6e-80 spoVAC S stage V sporulation protein AC
ICDKHGKO_01983 1e-195 spoVAD I Stage V sporulation protein AD
ICDKHGKO_01984 8.5e-57 spoVAE S stage V sporulation protein
ICDKHGKO_01985 5.8e-29 S Protein of unknown function (DUF1657)
ICDKHGKO_01986 4.7e-149 yetF1 S membrane
ICDKHGKO_01987 1.2e-70 S Protein of unknown function (DUF421)
ICDKHGKO_01988 2.7e-285 clsA_1 I PLD-like domain
ICDKHGKO_01989 2.5e-92 S Protein of unknown function (DUF421)
ICDKHGKO_01991 1.7e-66 S DinB family
ICDKHGKO_01992 8.5e-182 adhP 1.1.1.1 C alcohol dehydrogenase
ICDKHGKO_01993 4e-11
ICDKHGKO_01995 2.9e-26 S Protein of unknown function (DUF4025)
ICDKHGKO_01996 1.1e-10 ywlA S Uncharacterised protein family (UPF0715)
ICDKHGKO_01997 1.1e-128 yoaP 3.1.3.18 K YoaP-like
ICDKHGKO_01998 1.1e-90 J Acetyltransferase (GNAT) domain
ICDKHGKO_02000 1.4e-34
ICDKHGKO_02002 6.6e-100 ynaE S Domain of unknown function (DUF3885)
ICDKHGKO_02003 1.4e-187 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICDKHGKO_02004 1.1e-115 AA10,CBM73 S Pfam:Chitin_bind_3
ICDKHGKO_02006 3.3e-84 yvgO
ICDKHGKO_02008 0.0 yobO M Pectate lyase superfamily protein
ICDKHGKO_02009 1.3e-32 S TM2 domain
ICDKHGKO_02010 1.7e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
ICDKHGKO_02011 3.9e-24 S Domain of unknown function (DUF4177)
ICDKHGKO_02012 9.7e-128 yndL S Replication protein
ICDKHGKO_02014 2e-136 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
ICDKHGKO_02015 5.8e-66 yndM S Protein of unknown function (DUF2512)
ICDKHGKO_02016 1.3e-11 yoaW
ICDKHGKO_02017 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICDKHGKO_02018 1.2e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
ICDKHGKO_02019 1.6e-109 yneB L resolvase
ICDKHGKO_02020 9.8e-33 ynzC S UPF0291 protein
ICDKHGKO_02021 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICDKHGKO_02022 7.7e-79 yneE S Sporulation inhibitor of replication protein sirA
ICDKHGKO_02023 2.3e-28 yneF S UPF0154 protein
ICDKHGKO_02024 8.9e-23 ynzD S Spo0E like sporulation regulatory protein
ICDKHGKO_02025 1.2e-121 ccdA O cytochrome c biogenesis protein
ICDKHGKO_02026 1.2e-56 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
ICDKHGKO_02027 5.6e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
ICDKHGKO_02028 2.8e-70 yneK S Protein of unknown function (DUF2621)
ICDKHGKO_02029 5.7e-59 hspX O Spore coat protein
ICDKHGKO_02030 2.3e-19 sspP S Belongs to the SspP family
ICDKHGKO_02031 7.5e-15 sspO S Belongs to the SspO family
ICDKHGKO_02032 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ICDKHGKO_02033 3.6e-88 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ICDKHGKO_02035 1.1e-31 tlp S Belongs to the Tlp family
ICDKHGKO_02036 7.7e-73 yneP S Thioesterase-like superfamily
ICDKHGKO_02037 1.9e-49 yneQ
ICDKHGKO_02038 3.4e-43 yneR S Belongs to the HesB IscA family
ICDKHGKO_02039 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ICDKHGKO_02040 3.3e-68 yccU S CoA-binding protein
ICDKHGKO_02041 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICDKHGKO_02042 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ICDKHGKO_02043 4.6e-13
ICDKHGKO_02044 1.2e-39 ynfC
ICDKHGKO_02045 4e-246 agcS E Sodium alanine symporter
ICDKHGKO_02046 5.2e-22 yndG S DoxX-like family
ICDKHGKO_02047 1.3e-76 yndH S Domain of unknown function (DUF4166)
ICDKHGKO_02048 4.6e-275 yndJ S YndJ-like protein
ICDKHGKO_02049 1.2e-49 S Domain of unknown function (DUF4870)
ICDKHGKO_02050 3.2e-216 T PhoQ Sensor
ICDKHGKO_02051 3.4e-121 T Transcriptional regulatory protein, C terminal
ICDKHGKO_02052 6.5e-240 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
ICDKHGKO_02053 2.8e-277 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
ICDKHGKO_02054 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICDKHGKO_02055 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICDKHGKO_02056 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICDKHGKO_02057 4.5e-206 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
ICDKHGKO_02058 5.8e-122 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
ICDKHGKO_02059 5.4e-105 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
ICDKHGKO_02060 2.3e-114 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ICDKHGKO_02061 2.5e-164 bioI 1.14.14.46 C Cytochrome P450
ICDKHGKO_02062 8.5e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ICDKHGKO_02063 4e-122 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ICDKHGKO_02064 3.9e-199 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
ICDKHGKO_02065 1.6e-252 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
ICDKHGKO_02066 8.5e-134 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
ICDKHGKO_02067 1.6e-67 yngA S membrane
ICDKHGKO_02068 8.6e-154 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ICDKHGKO_02069 1.6e-103 yngC S SNARE associated Golgi protein
ICDKHGKO_02070 1.1e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
ICDKHGKO_02071 5.6e-133 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
ICDKHGKO_02072 1.6e-163 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
ICDKHGKO_02073 1.2e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
ICDKHGKO_02074 9e-240 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
ICDKHGKO_02075 2.7e-252 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
ICDKHGKO_02076 9.2e-36 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
ICDKHGKO_02077 5e-207 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
ICDKHGKO_02078 5.6e-294 yngK T Glycosyl hydrolase-like 10
ICDKHGKO_02079 5.1e-63 yngL S Protein of unknown function (DUF1360)
ICDKHGKO_02080 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
ICDKHGKO_02081 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICDKHGKO_02082 6.8e-257 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
ICDKHGKO_02083 3.4e-180 yoxA 5.1.3.3 G Aldose 1-epimerase
ICDKHGKO_02084 9.9e-242 yoeA V MATE efflux family protein
ICDKHGKO_02085 6.1e-94 yoeB S IseA DL-endopeptidase inhibitor
ICDKHGKO_02087 1.9e-95 L Integrase
ICDKHGKO_02088 1.1e-33 yoeD G Helix-turn-helix domain
ICDKHGKO_02089 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
ICDKHGKO_02090 5.4e-188 ybcL EGP Major facilitator Superfamily
ICDKHGKO_02091 6.7e-50 ybzH K Helix-turn-helix domain
ICDKHGKO_02092 1.1e-270 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICDKHGKO_02093 1.4e-289 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
ICDKHGKO_02094 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
ICDKHGKO_02095 3.6e-147 gltC K Transcriptional regulator
ICDKHGKO_02096 5.1e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICDKHGKO_02097 6.1e-135 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICDKHGKO_02098 3.6e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
ICDKHGKO_02099 6.9e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ICDKHGKO_02100 1.3e-37 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ICDKHGKO_02101 1.7e-115 yoxB
ICDKHGKO_02102 2.5e-92 S Protein of unknown function (DUF421)
ICDKHGKO_02103 2.7e-285 clsA_1 I PLD-like domain
ICDKHGKO_02104 1.2e-70 S Protein of unknown function (DUF421)
ICDKHGKO_02105 4.7e-149 yetF1 S membrane
ICDKHGKO_02106 5.8e-29 S Protein of unknown function (DUF1657)
ICDKHGKO_02107 8.5e-57 spoVAE S stage V sporulation protein
ICDKHGKO_02108 1e-195 spoVAD I Stage V sporulation protein AD
ICDKHGKO_02109 2.6e-80 spoVAC S stage V sporulation protein AC
ICDKHGKO_02110 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ICDKHGKO_02111 6e-26 S Protein of unknown function (DUF1657)
ICDKHGKO_02113 1.3e-78
ICDKHGKO_02114 7.1e-85 L resolvase
ICDKHGKO_02115 0.0 L Transposase and inactivated derivatives, TnpA family
ICDKHGKO_02116 2.3e-194 yoaB EGP Major facilitator Superfamily
ICDKHGKO_02117 1.2e-264 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
ICDKHGKO_02118 1e-159 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICDKHGKO_02119 1e-09 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICDKHGKO_02120 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICDKHGKO_02121 5.7e-27 yoaF
ICDKHGKO_02123 1.1e-93 hpr K helix_turn_helix multiple antibiotic resistance protein
ICDKHGKO_02124 1.1e-28
ICDKHGKO_02127 4.6e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
ICDKHGKO_02128 3.4e-121 yobQ K helix_turn_helix, arabinose operon control protein
ICDKHGKO_02129 7e-85 yobS K Transcriptional regulator
ICDKHGKO_02130 8.8e-125 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
ICDKHGKO_02131 7.9e-91 yobW
ICDKHGKO_02132 7.6e-55 czrA K transcriptional
ICDKHGKO_02133 3.3e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
ICDKHGKO_02134 1.4e-90 yozB S membrane
ICDKHGKO_02135 1.9e-133 yocB J Protein required for attachment to host cells
ICDKHGKO_02136 3.4e-91 yocC
ICDKHGKO_02137 5.3e-181 yocD 3.4.17.13 V peptidase S66
ICDKHGKO_02139 2.1e-112 yocH CBM50 M COG1388 FOG LysM repeat
ICDKHGKO_02140 0.0 recQ 3.6.4.12 L DNA helicase
ICDKHGKO_02142 1.1e-110 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICDKHGKO_02143 2e-56 dksA T general stress protein
ICDKHGKO_02144 6.3e-10 yocL
ICDKHGKO_02145 9.8e-09
ICDKHGKO_02146 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
ICDKHGKO_02147 2e-29 yozN
ICDKHGKO_02148 2.5e-36 yocN
ICDKHGKO_02149 2.4e-56 yozO S Bacterial PH domain
ICDKHGKO_02151 1.6e-31 yozC
ICDKHGKO_02152 5.1e-284 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
ICDKHGKO_02153 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
ICDKHGKO_02154 8.1e-162 sodA 1.15.1.1 P Superoxide dismutase
ICDKHGKO_02155 7.1e-229 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
ICDKHGKO_02156 1.8e-157 yocS S -transporter
ICDKHGKO_02157 8e-123 S Metallo-beta-lactamase superfamily
ICDKHGKO_02158 2.9e-184 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
ICDKHGKO_02159 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
ICDKHGKO_02160 0.0 yojO P Von Willebrand factor
ICDKHGKO_02161 6.5e-162 yojN S ATPase family associated with various cellular activities (AAA)
ICDKHGKO_02162 1.2e-98 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ICDKHGKO_02163 2.1e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
ICDKHGKO_02164 5.1e-218 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
ICDKHGKO_02165 2.3e-105 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ICDKHGKO_02167 1.1e-232 norM V Multidrug efflux pump
ICDKHGKO_02168 6.2e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ICDKHGKO_02169 9.6e-126 yojG S deacetylase
ICDKHGKO_02170 3.7e-60 yojF S Protein of unknown function (DUF1806)
ICDKHGKO_02171 6.4e-23
ICDKHGKO_02172 2.6e-158 rarD S -transporter
ICDKHGKO_02173 8.9e-78 yozR S COG0071 Molecular chaperone (small heat shock protein)
ICDKHGKO_02175 6.8e-63 yodA S tautomerase
ICDKHGKO_02176 3.5e-52 yodB K transcriptional
ICDKHGKO_02177 2.8e-103 yodC C nitroreductase
ICDKHGKO_02178 7.2e-92 mhqD S Carboxylesterase
ICDKHGKO_02179 1.8e-167 yodE E COG0346 Lactoylglutathione lyase and related lyases
ICDKHGKO_02180 3.1e-19 S Protein of unknown function (DUF3311)
ICDKHGKO_02181 3.2e-262 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICDKHGKO_02182 2.1e-266 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
ICDKHGKO_02183 1.6e-282 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ICDKHGKO_02184 3.8e-128 yydK K Transcriptional regulator
ICDKHGKO_02185 5.5e-248 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
ICDKHGKO_02186 2.2e-120 yodH Q Methyltransferase
ICDKHGKO_02187 1e-19 yodI
ICDKHGKO_02188 7.6e-141 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
ICDKHGKO_02189 7.7e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
ICDKHGKO_02191 3.3e-55 yodL S YodL-like
ICDKHGKO_02192 4.4e-101 yodM 3.6.1.27 I Acid phosphatase homologues
ICDKHGKO_02193 1.8e-23 yozD S YozD-like protein
ICDKHGKO_02195 4.6e-120 yodN
ICDKHGKO_02196 6.1e-51 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICDKHGKO_02197 3.4e-35 yozE S Belongs to the UPF0346 family
ICDKHGKO_02198 1.1e-43 yokU S YokU-like protein, putative antitoxin
ICDKHGKO_02199 1.6e-274 kamA 5.4.3.2 E lysine 2,3-aminomutase
ICDKHGKO_02200 1.4e-140 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
ICDKHGKO_02201 1e-248 yodQ 3.5.1.16 E Acetylornithine deacetylase
ICDKHGKO_02202 2.7e-118 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
ICDKHGKO_02203 1.5e-121 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ICDKHGKO_02204 3e-235 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ICDKHGKO_02206 5.4e-64 yosT L Bacterial transcription activator, effector binding domain
ICDKHGKO_02208 1.3e-137 yiiD K acetyltransferase
ICDKHGKO_02209 7e-226 cgeD M maturation of the outermost layer of the spore
ICDKHGKO_02210 1.4e-36 cgeC
ICDKHGKO_02211 3.1e-48 cgeA
ICDKHGKO_02212 7.7e-169 cgeB S Spore maturation protein
ICDKHGKO_02213 4.1e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
ICDKHGKO_02214 1.2e-69 4.2.1.115 GM Polysaccharide biosynthesis protein
ICDKHGKO_02217 1.9e-121 lldD 1.13.12.4 C FMN-dependent dehydrogenase
ICDKHGKO_02219 1.9e-13 S Regulatory protein YrvL
ICDKHGKO_02220 6.4e-211 yokA L Recombinase
ICDKHGKO_02221 1.2e-100 4.2.1.115 GM Polysaccharide biosynthesis protein
ICDKHGKO_02222 6.4e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ICDKHGKO_02223 4.3e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICDKHGKO_02224 3.1e-66 ypoP K transcriptional
ICDKHGKO_02225 1.7e-94 ypmS S protein conserved in bacteria
ICDKHGKO_02226 9.5e-130 ypmR E GDSL-like Lipase/Acylhydrolase
ICDKHGKO_02227 2e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
ICDKHGKO_02228 7.5e-39 ypmP S Protein of unknown function (DUF2535)
ICDKHGKO_02229 1.3e-240 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICDKHGKO_02230 3.8e-163 pspF K Transcriptional regulator
ICDKHGKO_02231 6.6e-108 hlyIII S protein, Hemolysin III
ICDKHGKO_02232 1.7e-108 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
ICDKHGKO_02233 7.8e-85 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ICDKHGKO_02234 2.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICDKHGKO_02235 3e-110 ypjP S YpjP-like protein
ICDKHGKO_02236 2.9e-126 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
ICDKHGKO_02237 1.7e-75 yphP S Belongs to the UPF0403 family
ICDKHGKO_02238 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
ICDKHGKO_02239 6e-152 ypgR C COG0694 Thioredoxin-like proteins and domains
ICDKHGKO_02240 2.3e-89 ypgQ S phosphohydrolase
ICDKHGKO_02241 2.1e-82 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
ICDKHGKO_02243 2.8e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICDKHGKO_02244 1.4e-212 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
ICDKHGKO_02245 1e-30 cspD K Cold-shock protein
ICDKHGKO_02246 6.3e-11 degR
ICDKHGKO_02247 2.3e-35 S Protein of unknown function (DUF2564)
ICDKHGKO_02248 3.7e-27 ypeQ S Zinc-finger
ICDKHGKO_02249 2e-118 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
ICDKHGKO_02250 5.2e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ICDKHGKO_02251 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
ICDKHGKO_02253 8e-160 polA 2.7.7.7 L 5'3' exonuclease
ICDKHGKO_02255 3.7e-33 ypbS S Protein of unknown function (DUF2533)
ICDKHGKO_02256 0.0 ypbR S Dynamin family
ICDKHGKO_02257 8.8e-85 ypbQ S protein conserved in bacteria
ICDKHGKO_02258 1.2e-194 bcsA Q Naringenin-chalcone synthase
ICDKHGKO_02259 2e-101 J Acetyltransferase (GNAT) domain
ICDKHGKO_02260 6.6e-45 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
ICDKHGKO_02261 2.4e-07 S Bacillus cereus group antimicrobial protein
ICDKHGKO_02262 5.1e-232 pbuX F xanthine
ICDKHGKO_02263 2.9e-94 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ICDKHGKO_02264 1.9e-286 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ICDKHGKO_02265 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
ICDKHGKO_02267 6.6e-22 S YpzG-like protein
ICDKHGKO_02268 2e-74 yqgA
ICDKHGKO_02269 1.3e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
ICDKHGKO_02270 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ICDKHGKO_02271 5.9e-97 ypsA S Belongs to the UPF0398 family
ICDKHGKO_02272 8.5e-24 cotD S Inner spore coat protein D
ICDKHGKO_02274 7.5e-225 yprB L RNase_H superfamily
ICDKHGKO_02275 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
ICDKHGKO_02276 1.3e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
ICDKHGKO_02277 4.4e-60 hspX O Belongs to the small heat shock protein (HSP20) family
ICDKHGKO_02278 4.4e-38 yppG S YppG-like protein
ICDKHGKO_02280 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
ICDKHGKO_02283 9.2e-178 yppC S Protein of unknown function (DUF2515)
ICDKHGKO_02284 1.2e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ICDKHGKO_02285 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ICDKHGKO_02286 1.4e-86 ypoC
ICDKHGKO_02287 7.8e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICDKHGKO_02288 3.4e-129 dnaD L DNA replication protein DnaD
ICDKHGKO_02289 7.1e-250 asnS 6.1.1.22 J asparaginyl-tRNA
ICDKHGKO_02290 2.9e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
ICDKHGKO_02291 1.4e-73 ypmB S protein conserved in bacteria
ICDKHGKO_02292 6.7e-23 ypmA S Protein of unknown function (DUF4264)
ICDKHGKO_02293 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
ICDKHGKO_02294 3.9e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ICDKHGKO_02295 1.2e-152 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ICDKHGKO_02296 2e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
ICDKHGKO_02297 4.9e-179 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ICDKHGKO_02298 5.6e-209 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ICDKHGKO_02299 1.7e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
ICDKHGKO_02300 1e-125 bshB1 S proteins, LmbE homologs
ICDKHGKO_02301 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
ICDKHGKO_02302 3.8e-145 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ICDKHGKO_02303 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
ICDKHGKO_02304 4.7e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
ICDKHGKO_02305 2.5e-222 oxdC 4.1.1.2 G Oxalate decarboxylase
ICDKHGKO_02306 1.5e-138 ypjB S sporulation protein
ICDKHGKO_02307 5.2e-99 ypjA S membrane
ICDKHGKO_02308 5.7e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
ICDKHGKO_02309 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
ICDKHGKO_02310 8.7e-95 qcrA C Menaquinol-cytochrome c reductase
ICDKHGKO_02311 8.3e-73 ypiF S Protein of unknown function (DUF2487)
ICDKHGKO_02312 8.1e-99 ypiB S Belongs to the UPF0302 family
ICDKHGKO_02313 1.5e-228 S COG0457 FOG TPR repeat
ICDKHGKO_02314 1.1e-226 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
ICDKHGKO_02315 1.8e-201 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
ICDKHGKO_02316 3.1e-198 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICDKHGKO_02317 5.5e-136 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
ICDKHGKO_02318 5.6e-225 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ICDKHGKO_02319 3.3e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
ICDKHGKO_02320 3e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
ICDKHGKO_02321 6.3e-153 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICDKHGKO_02322 5.8e-283 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICDKHGKO_02323 1.7e-58 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
ICDKHGKO_02324 6.3e-199 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ICDKHGKO_02325 2.3e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ICDKHGKO_02326 7.4e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
ICDKHGKO_02327 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
ICDKHGKO_02328 4.8e-196 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICDKHGKO_02329 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ICDKHGKO_02330 1.5e-135 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
ICDKHGKO_02331 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
ICDKHGKO_02332 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
ICDKHGKO_02333 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ICDKHGKO_02334 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ICDKHGKO_02335 1.3e-10 yphF
ICDKHGKO_02336 3.5e-129 yphF
ICDKHGKO_02337 1.5e-16 yphE S Protein of unknown function (DUF2768)
ICDKHGKO_02338 5.2e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
ICDKHGKO_02339 1.8e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
ICDKHGKO_02340 2.4e-99 yphA
ICDKHGKO_02341 4.7e-08 S YpzI-like protein
ICDKHGKO_02342 1.5e-178 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ICDKHGKO_02343 2.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
ICDKHGKO_02344 7.5e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
ICDKHGKO_02345 2.5e-12 S Family of unknown function (DUF5359)
ICDKHGKO_02346 1.1e-57 ypfA M Flagellar protein YcgR
ICDKHGKO_02347 2.5e-245 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
ICDKHGKO_02348 4.7e-149 sleB 3.5.1.28 M Spore cortex-lytic enzyme
ICDKHGKO_02349 1.6e-120 prsW S Involved in the degradation of specific anti-sigma factors
ICDKHGKO_02350 7.2e-186 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
ICDKHGKO_02351 2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
ICDKHGKO_02352 2.2e-105 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
ICDKHGKO_02353 1.9e-141 ypbG S Calcineurin-like phosphoesterase superfamily domain
ICDKHGKO_02354 2.4e-83 ypbF S Protein of unknown function (DUF2663)
ICDKHGKO_02355 3.7e-60 ypbE M Lysin motif
ICDKHGKO_02356 1.6e-95 ypbD S metal-dependent membrane protease
ICDKHGKO_02357 2.5e-275 recQ 3.6.4.12 L DNA helicase
ICDKHGKO_02358 1.5e-189 ypbB 5.1.3.1 S protein conserved in bacteria
ICDKHGKO_02359 3.6e-41 fer C Ferredoxin
ICDKHGKO_02360 1.6e-92 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ICDKHGKO_02361 2.2e-290 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICDKHGKO_02362 2.3e-169 rsiX
ICDKHGKO_02363 2.2e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
ICDKHGKO_02364 0.0 resE 2.7.13.3 T Histidine kinase
ICDKHGKO_02365 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICDKHGKO_02366 1.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
ICDKHGKO_02367 1.1e-308 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
ICDKHGKO_02368 3.4e-97 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
ICDKHGKO_02369 6.4e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ICDKHGKO_02370 3.8e-88 spmB S Spore maturation protein
ICDKHGKO_02371 1.3e-102 spmA S Spore maturation protein
ICDKHGKO_02372 1.1e-209 dacB 3.4.16.4 M Belongs to the peptidase S11 family
ICDKHGKO_02373 8.1e-82 ypuI S Protein of unknown function (DUF3907)
ICDKHGKO_02374 5.1e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICDKHGKO_02375 3.1e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ICDKHGKO_02377 6.2e-88 ypuF S Domain of unknown function (DUF309)
ICDKHGKO_02378 1e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICDKHGKO_02379 5.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
ICDKHGKO_02380 2.3e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ICDKHGKO_02381 7.2e-110 ribE 2.5.1.9 H Riboflavin synthase
ICDKHGKO_02382 6.2e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICDKHGKO_02383 5.1e-46 ypuD
ICDKHGKO_02384 3.6e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
ICDKHGKO_02385 8.5e-79 ccdC1 O Protein of unknown function (DUF1453)
ICDKHGKO_02386 5.7e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICDKHGKO_02387 2.6e-150 ypuA S Secreted protein
ICDKHGKO_02388 1.9e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ICDKHGKO_02389 6.2e-266 spoVAF EG Stage V sporulation protein AF
ICDKHGKO_02390 2.4e-107 spoVAEA S stage V sporulation protein
ICDKHGKO_02391 2.5e-56 spoVAEB S stage V sporulation protein
ICDKHGKO_02392 3.5e-188 spoVAD I Stage V sporulation protein AD
ICDKHGKO_02393 1.3e-78 spoVAC S stage V sporulation protein AC
ICDKHGKO_02394 4.5e-68 spoVAB S Stage V sporulation protein AB
ICDKHGKO_02395 1.5e-109 spoVAA S Stage V sporulation protein AA
ICDKHGKO_02396 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICDKHGKO_02397 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
ICDKHGKO_02398 2.3e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
ICDKHGKO_02399 5.9e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
ICDKHGKO_02400 4.2e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ICDKHGKO_02401 2.7e-227 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICDKHGKO_02402 2.7e-163 xerD L recombinase XerD
ICDKHGKO_02403 6.4e-37 S Protein of unknown function (DUF4227)
ICDKHGKO_02404 2.7e-79 fur P Belongs to the Fur family
ICDKHGKO_02405 2.7e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
ICDKHGKO_02406 8.1e-32 yqkK
ICDKHGKO_02407 3e-23
ICDKHGKO_02408 3.6e-241 mleA 1.1.1.38 C malic enzyme
ICDKHGKO_02409 1.9e-240 mleN C Na H antiporter
ICDKHGKO_02410 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
ICDKHGKO_02411 1.2e-183 ansA 3.5.1.1 EJ L-asparaginase
ICDKHGKO_02412 5e-57 ansR K Transcriptional regulator
ICDKHGKO_02413 2.5e-214 yqxK 3.6.4.12 L DNA helicase
ICDKHGKO_02414 9e-93 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
ICDKHGKO_02416 1.2e-163 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
ICDKHGKO_02418 1.3e-131 yqkD S COG1073 Hydrolases of the alpha beta superfamily
ICDKHGKO_02419 3.2e-39 yqkC S Protein of unknown function (DUF2552)
ICDKHGKO_02420 1.6e-58 yqkB S Belongs to the HesB IscA family
ICDKHGKO_02421 1.4e-165 yqkA K GrpB protein
ICDKHGKO_02423 2.8e-87 yqjY K acetyltransferase
ICDKHGKO_02424 5.7e-233 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICDKHGKO_02425 9.3e-56 S YolD-like protein
ICDKHGKO_02427 3.3e-144 yueF S transporter activity
ICDKHGKO_02429 5e-176 coaA 2.7.1.33 F Pantothenic acid kinase
ICDKHGKO_02430 1.1e-242 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
ICDKHGKO_02431 1.8e-136 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
ICDKHGKO_02432 2.3e-168 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
ICDKHGKO_02433 7.9e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICDKHGKO_02434 1.8e-156 K LysR substrate binding domain
ICDKHGKO_02435 1.6e-46 S GlpM protein
ICDKHGKO_02436 3.9e-94 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
ICDKHGKO_02437 8.8e-50 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
ICDKHGKO_02438 4.5e-143 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ICDKHGKO_02439 4e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICDKHGKO_02440 2.8e-168 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ICDKHGKO_02441 7.7e-285 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICDKHGKO_02442 1.3e-265 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ICDKHGKO_02443 9.4e-231 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICDKHGKO_02444 7.4e-27 yqzJ
ICDKHGKO_02445 2.1e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICDKHGKO_02446 5.8e-200 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
ICDKHGKO_02447 2e-283 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
ICDKHGKO_02448 2e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
ICDKHGKO_02450 3.6e-91 yqjB S protein conserved in bacteria
ICDKHGKO_02451 7.7e-169 yqjA S Putative aromatic acid exporter C-terminal domain
ICDKHGKO_02452 5.2e-125 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ICDKHGKO_02453 1.1e-105 artQ E COG0765 ABC-type amino acid transport system, permease component
ICDKHGKO_02454 4.2e-133 artP ET Belongs to the bacterial solute-binding protein 3 family
ICDKHGKO_02455 1e-75 yqiW S Belongs to the UPF0403 family
ICDKHGKO_02456 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
ICDKHGKO_02457 3.5e-193 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ICDKHGKO_02458 6.7e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ICDKHGKO_02459 7.8e-164 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ICDKHGKO_02460 5.7e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ICDKHGKO_02461 2e-205 buk 2.7.2.7 C Belongs to the acetokinase family
ICDKHGKO_02462 2.6e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
ICDKHGKO_02463 1.3e-149 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
ICDKHGKO_02464 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
ICDKHGKO_02465 2.7e-33 yqzF S Protein of unknown function (DUF2627)
ICDKHGKO_02466 7.1e-156 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ICDKHGKO_02467 7.8e-266 prpD 4.2.1.79 S 2-methylcitrate dehydratase
ICDKHGKO_02468 3.5e-205 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
ICDKHGKO_02469 5.3e-201 mmgC I acyl-CoA dehydrogenase
ICDKHGKO_02470 9.1e-46 hbdA 1.1.1.157 I Dehydrogenase
ICDKHGKO_02471 2.9e-78 hbdA 1.1.1.157 I Dehydrogenase
ICDKHGKO_02472 3.2e-209 mmgA 2.3.1.9 I Belongs to the thiolase family
ICDKHGKO_02473 9.6e-127 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ICDKHGKO_02474 1.4e-97 amiC 3.5.1.28 M Cell wall hydrolase autolysin
ICDKHGKO_02475 5.7e-17
ICDKHGKO_02476 2.3e-92 ytaF P Probably functions as a manganese efflux pump
ICDKHGKO_02477 3.7e-111 K Protein of unknown function (DUF1232)
ICDKHGKO_02479 5.8e-208 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
ICDKHGKO_02482 7e-204 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICDKHGKO_02484 2.7e-143 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
ICDKHGKO_02485 3.2e-234 rseP 3.4.21.116 M Stage IV sporulation protein B
ICDKHGKO_02486 6.2e-310 recN L May be involved in recombinational repair of damaged DNA
ICDKHGKO_02487 4.3e-77 argR K Regulates arginine biosynthesis genes
ICDKHGKO_02488 9.9e-152 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
ICDKHGKO_02489 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ICDKHGKO_02490 7e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ICDKHGKO_02491 1.3e-38 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICDKHGKO_02492 2.5e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ICDKHGKO_02493 5.7e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ICDKHGKO_02494 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICDKHGKO_02495 1.4e-66 yqhY S protein conserved in bacteria
ICDKHGKO_02496 8.4e-254 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
ICDKHGKO_02497 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ICDKHGKO_02498 1.3e-58 spoIIIAH S SpoIIIAH-like protein
ICDKHGKO_02499 1.4e-114 spoIIIAG S stage III sporulation protein AG
ICDKHGKO_02500 1e-100 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
ICDKHGKO_02501 4.1e-199 spoIIIAE S stage III sporulation protein AE
ICDKHGKO_02502 3.3e-41 spoIIIAD S Stage III sporulation protein AD
ICDKHGKO_02503 7.6e-29 spoIIIAC S stage III sporulation protein AC
ICDKHGKO_02504 1e-82 spoIIIAB S Stage III sporulation protein
ICDKHGKO_02505 1.7e-165 spoIIIAA S stage III sporulation protein AA
ICDKHGKO_02506 6.7e-36 yqhV S Protein of unknown function (DUF2619)
ICDKHGKO_02507 2.1e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICDKHGKO_02508 5.9e-170 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
ICDKHGKO_02509 1.1e-84 yqhR S Conserved membrane protein YqhR
ICDKHGKO_02510 9.1e-170 yqhQ S Protein of unknown function (DUF1385)
ICDKHGKO_02511 1.2e-59 yqhP
ICDKHGKO_02512 5.1e-159 yqhO S esterase of the alpha-beta hydrolase superfamily
ICDKHGKO_02513 4.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
ICDKHGKO_02514 4.1e-158 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
ICDKHGKO_02515 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
ICDKHGKO_02516 3.6e-282 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICDKHGKO_02517 1.2e-247 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICDKHGKO_02518 5.7e-200 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
ICDKHGKO_02519 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
ICDKHGKO_02520 3e-150 yqhG S Bacterial protein YqhG of unknown function
ICDKHGKO_02521 1.7e-21 sinI S Anti-repressor SinI
ICDKHGKO_02522 3.9e-54 sinR K transcriptional
ICDKHGKO_02523 1.5e-138 tasA S Cell division protein FtsN
ICDKHGKO_02524 5.2e-67 sipW 3.4.21.89 U Signal peptidase
ICDKHGKO_02525 3.6e-112 yqxM
ICDKHGKO_02526 1.1e-53 yqzG S Protein of unknown function (DUF3889)
ICDKHGKO_02527 1.5e-25 yqzE S YqzE-like protein
ICDKHGKO_02528 5.4e-57 S ComG operon protein 7
ICDKHGKO_02529 4.1e-21 comGF U Putative Competence protein ComGF
ICDKHGKO_02530 1.2e-20 comGE
ICDKHGKO_02531 6.4e-70 gspH NU Tfp pilus assembly protein FimT
ICDKHGKO_02532 1.3e-48 comGC U Required for transformation and DNA binding
ICDKHGKO_02533 4e-179 comGB NU COG1459 Type II secretory pathway, component PulF
ICDKHGKO_02534 8.9e-198 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICDKHGKO_02535 6.7e-181 corA P Mg2 transporter protein
ICDKHGKO_02536 1.5e-231 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
ICDKHGKO_02537 3e-137 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ICDKHGKO_02539 1.9e-62 yqgZ 1.20.4.1 P Belongs to the ArsC family
ICDKHGKO_02540 3.1e-37 yqgY S Protein of unknown function (DUF2626)
ICDKHGKO_02541 3.6e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
ICDKHGKO_02542 5.4e-20 yqgW S Protein of unknown function (DUF2759)
ICDKHGKO_02543 1.7e-48 yqgV S Thiamine-binding protein
ICDKHGKO_02544 2.3e-187 yqgU
ICDKHGKO_02545 5.3e-201 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
ICDKHGKO_02546 1.8e-178 glcK 2.7.1.2 G Glucokinase
ICDKHGKO_02547 1.6e-27 yqgQ S Protein conserved in bacteria
ICDKHGKO_02548 4.8e-203 nhaC C Na H antiporter
ICDKHGKO_02549 4e-07 yqgO
ICDKHGKO_02550 6e-89 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICDKHGKO_02551 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ICDKHGKO_02552 1.2e-50 yqzD
ICDKHGKO_02553 1.3e-73 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICDKHGKO_02554 6.4e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICDKHGKO_02555 2.2e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ICDKHGKO_02556 8.5e-154 pstA P Phosphate transport system permease
ICDKHGKO_02557 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
ICDKHGKO_02558 2.3e-154 pstS P Phosphate
ICDKHGKO_02559 0.0 pbpA 3.4.16.4 M penicillin-binding protein
ICDKHGKO_02560 3.3e-223 yqgE EGP Major facilitator superfamily
ICDKHGKO_02561 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
ICDKHGKO_02562 4.2e-70 yqgC S protein conserved in bacteria
ICDKHGKO_02563 2.4e-128 yqgB S Protein of unknown function (DUF1189)
ICDKHGKO_02564 4.2e-44 yqfZ M LysM domain
ICDKHGKO_02565 5e-199 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ICDKHGKO_02566 6.7e-52 yqfX S membrane
ICDKHGKO_02567 6.7e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
ICDKHGKO_02568 2.4e-71 zur P Belongs to the Fur family
ICDKHGKO_02569 1.1e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
ICDKHGKO_02570 9.3e-37 yqfT S Protein of unknown function (DUF2624)
ICDKHGKO_02571 2.9e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ICDKHGKO_02572 5.7e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ICDKHGKO_02573 1.6e-25 yqfQ S YqfQ-like protein
ICDKHGKO_02574 1.9e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ICDKHGKO_02575 1.8e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ICDKHGKO_02576 1.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
ICDKHGKO_02577 1.3e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
ICDKHGKO_02578 3.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ICDKHGKO_02579 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ICDKHGKO_02580 8.7e-87 yaiI S Belongs to the UPF0178 family
ICDKHGKO_02581 1.4e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
ICDKHGKO_02582 1.3e-111 ccpN K CBS domain
ICDKHGKO_02583 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
ICDKHGKO_02584 3.7e-173 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
ICDKHGKO_02585 3e-139 recO L Involved in DNA repair and RecF pathway recombination
ICDKHGKO_02586 1.8e-16 S YqzL-like protein
ICDKHGKO_02587 5.2e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICDKHGKO_02588 2.7e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
ICDKHGKO_02589 8.6e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
ICDKHGKO_02590 9.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICDKHGKO_02591 0.0 yqfF S membrane-associated HD superfamily hydrolase
ICDKHGKO_02592 2.1e-174 phoH T Phosphate starvation-inducible protein PhoH
ICDKHGKO_02593 1.1e-207 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
ICDKHGKO_02594 9.3e-46 yqfC S sporulation protein YqfC
ICDKHGKO_02595 4.5e-23 yqfB
ICDKHGKO_02596 5.3e-120 yqfA S UPF0365 protein
ICDKHGKO_02597 6.1e-225 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
ICDKHGKO_02598 1.2e-68 yqeY S Yqey-like protein
ICDKHGKO_02599 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
ICDKHGKO_02600 1.7e-152 yqeW P COG1283 Na phosphate symporter
ICDKHGKO_02601 1.5e-258 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
ICDKHGKO_02602 2.8e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ICDKHGKO_02603 6.6e-173 prmA J Methylates ribosomal protein L11
ICDKHGKO_02604 2.7e-197 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ICDKHGKO_02605 0.0 dnaK O Heat shock 70 kDa protein
ICDKHGKO_02606 8.9e-72 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICDKHGKO_02607 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ICDKHGKO_02608 2.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
ICDKHGKO_02609 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ICDKHGKO_02610 3.8e-54 yqxA S Protein of unknown function (DUF3679)
ICDKHGKO_02611 2.4e-220 spoIIP M stage II sporulation protein P
ICDKHGKO_02612 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ICDKHGKO_02613 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
ICDKHGKO_02614 2.7e-180 holA 2.7.7.7 L DNA polymerase III delta subunit
ICDKHGKO_02615 0.0 comEC S Competence protein ComEC
ICDKHGKO_02616 8e-105 comEB 3.5.4.12 F ComE operon protein 2
ICDKHGKO_02617 7.3e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
ICDKHGKO_02618 4.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ICDKHGKO_02619 3.2e-138 yqeM Q Methyltransferase
ICDKHGKO_02620 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ICDKHGKO_02621 1.8e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
ICDKHGKO_02622 9.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICDKHGKO_02623 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
ICDKHGKO_02624 1.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ICDKHGKO_02625 3.8e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
ICDKHGKO_02626 2e-94 yqeG S hydrolase of the HAD superfamily
ICDKHGKO_02628 4.1e-138 yqeF E GDSL-like Lipase/Acylhydrolase
ICDKHGKO_02629 8.4e-139 3.5.1.104 G Polysaccharide deacetylase
ICDKHGKO_02630 3.6e-106 yqeD S SNARE associated Golgi protein
ICDKHGKO_02631 3.2e-10 2.3.1.57 K Acetyltransferase (GNAT) domain
ICDKHGKO_02633 1.4e-215 EGP Major facilitator Superfamily
ICDKHGKO_02634 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICDKHGKO_02635 1.6e-14 cisA2 L Recombinase
ICDKHGKO_02636 8.1e-151 smc L AAA ATPase domain
ICDKHGKO_02637 1e-40 IQ Enoyl-(Acyl carrier protein) reductase
ICDKHGKO_02638 3.8e-07 Q non-ribosomal peptide synthetase
ICDKHGKO_02640 4.5e-160 efpA EGP Major facilitator superfamily
ICDKHGKO_02641 4.3e-77 pabA 2.6.1.85, 4.1.3.27 EH TIGRFAM glutamine amidotransferase of anthranilate synthase
ICDKHGKO_02642 5.8e-181 trpE 4.1.3.27 EH Anthranilate synthase component I domain protein
ICDKHGKO_02643 1.2e-175 6.2.1.30 H phenylacetate-CoA ligase activity
ICDKHGKO_02644 0.0 Q AMP-binding enzyme C-terminal domain
ICDKHGKO_02645 7.2e-124 S Winged helix DNA-binding domain
ICDKHGKO_02646 6.1e-204 glyA_1 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICDKHGKO_02647 3.3e-114 mchB Q Thioesterase involved in non-ribosomal peptide biosynthesis
ICDKHGKO_02649 4.1e-162 yobV9 K HTH domain
ICDKHGKO_02650 3.1e-105 yoaZ S DJ-1/PfpI family
ICDKHGKO_02651 6.4e-19
ICDKHGKO_02655 1e-14 S SMI1-KNR4 cell-wall
ICDKHGKO_02656 1.7e-20 S SMI1-KNR4 cell-wall
ICDKHGKO_02658 1e-13 xkdS S Protein of unknown function (DUF2634)
ICDKHGKO_02659 2.9e-109 5.1.1.13 M Belongs to the aspartate glutamate racemases family
ICDKHGKO_02660 6.6e-25 xkdR S Protein of unknown function (DUF2577)
ICDKHGKO_02661 1.1e-137 yvgN 1.1.1.346 S Reductase
ICDKHGKO_02662 3.2e-69 K MerR family transcriptional regulator
ICDKHGKO_02663 5.7e-16 xkdG S Phage capsid family
ICDKHGKO_02664 1.2e-157 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
ICDKHGKO_02665 2.3e-60 K Transcriptional regulator PadR-like family
ICDKHGKO_02666 1e-36 ydeE K AraC family transcriptional regulator
ICDKHGKO_02668 4.4e-97 adk 2.7.4.3 F adenylate kinase activity
ICDKHGKO_02669 2.8e-220 tetL EGP Major facilitator Superfamily
ICDKHGKO_02670 3.3e-81 yyaR K Acetyltransferase (GNAT) domain
ICDKHGKO_02671 4.4e-91 yrdA S DinB family
ICDKHGKO_02673 8.5e-145 S hydrolase
ICDKHGKO_02674 1.7e-72 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
ICDKHGKO_02675 1.2e-51 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
ICDKHGKO_02676 7.8e-129 glvR K Helix-turn-helix domain, rpiR family
ICDKHGKO_02677 5.8e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
ICDKHGKO_02678 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
ICDKHGKO_02679 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
ICDKHGKO_02680 1.3e-179 romA S Beta-lactamase superfamily domain
ICDKHGKO_02681 8.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ICDKHGKO_02682 4.1e-164 yybE K Transcriptional regulator
ICDKHGKO_02683 3.8e-213 ynfM EGP Major facilitator Superfamily
ICDKHGKO_02684 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
ICDKHGKO_02685 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
ICDKHGKO_02686 1.5e-92 yrhH Q methyltransferase
ICDKHGKO_02688 8.8e-142 focA P Formate nitrite
ICDKHGKO_02689 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
ICDKHGKO_02690 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
ICDKHGKO_02691 7e-81 yrhD S Protein of unknown function (DUF1641)
ICDKHGKO_02692 1.3e-34 yrhC S YrhC-like protein
ICDKHGKO_02693 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ICDKHGKO_02694 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
ICDKHGKO_02695 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ICDKHGKO_02696 7.1e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
ICDKHGKO_02697 4.1e-27 yrzA S Protein of unknown function (DUF2536)
ICDKHGKO_02698 2.6e-68 yrrS S Protein of unknown function (DUF1510)
ICDKHGKO_02699 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
ICDKHGKO_02700 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ICDKHGKO_02702 4.2e-08
ICDKHGKO_02704 4.7e-106 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ICDKHGKO_02705 2.2e-59 S Pfam:Phage_holin_4_1
ICDKHGKO_02708 5.6e-145 S Domain of unknown function (DUF2479)
ICDKHGKO_02709 0.0 M Pectate lyase superfamily protein
ICDKHGKO_02710 5.5e-258 NU Prophage endopeptidase tail
ICDKHGKO_02711 2.1e-117 S Phage tail protein
ICDKHGKO_02712 0.0 D Phage tail tape measure protein
ICDKHGKO_02714 5.4e-32
ICDKHGKO_02715 2.4e-07
ICDKHGKO_02716 1.9e-33 S Bacteriophage HK97-gp10, putative tail-component
ICDKHGKO_02717 4.9e-30 S Phage head-tail joining protein
ICDKHGKO_02718 1.7e-21 S Phage gp6-like head-tail connector protein
ICDKHGKO_02719 4.7e-18
ICDKHGKO_02720 9.5e-124 S capsid protein
ICDKHGKO_02721 1.2e-74 pi136 S Caudovirus prohead serine protease
ICDKHGKO_02722 6.4e-176 S portal protein
ICDKHGKO_02724 8.4e-150 terL S Terminase
ICDKHGKO_02725 2.1e-56 terS L Terminase, small subunit
ICDKHGKO_02727 3.1e-09 ftsK D PFAM cell divisionFtsK SpoIIIE
ICDKHGKO_02728 1e-72 L Phage integrase family
ICDKHGKO_02729 2.5e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
ICDKHGKO_02734 1.6e-46 S dUTPase
ICDKHGKO_02736 2.7e-167 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
ICDKHGKO_02739 3.6e-15 yqaO S Phage-like element PBSX protein XtrA
ICDKHGKO_02743 1.5e-28
ICDKHGKO_02746 8.2e-42 dnaC L IstB-like ATP binding protein
ICDKHGKO_02747 3.2e-68 L dnaD_dom DnaD domain protein
ICDKHGKO_02749 2.7e-07 K Cupin domain
ICDKHGKO_02750 1.2e-27 K Helix-turn-helix XRE-family like proteins
ICDKHGKO_02753 1.4e-121
ICDKHGKO_02754 2.1e-67 L Arm DNA-binding domain
ICDKHGKO_02755 7.5e-112 udk 2.7.1.48 F Cytidine monophosphokinase
ICDKHGKO_02756 1.6e-246 yegQ O COG0826 Collagenase and related proteases
ICDKHGKO_02757 2.9e-173 yegQ O Peptidase U32
ICDKHGKO_02758 4e-116 yrrM 2.1.1.104 S O-methyltransferase
ICDKHGKO_02759 6.9e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICDKHGKO_02760 7.1e-46 yrzB S Belongs to the UPF0473 family
ICDKHGKO_02761 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICDKHGKO_02762 1.7e-41 yrzL S Belongs to the UPF0297 family
ICDKHGKO_02763 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICDKHGKO_02764 2.1e-159 yrrI S AI-2E family transporter
ICDKHGKO_02765 2.5e-127 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ICDKHGKO_02766 4.4e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
ICDKHGKO_02767 8e-109 gluC P ABC transporter
ICDKHGKO_02768 6e-104 glnP P ABC transporter
ICDKHGKO_02769 2.1e-08 S Protein of unknown function (DUF3918)
ICDKHGKO_02770 2.9e-30 yrzR
ICDKHGKO_02771 2.3e-78 yrrD S protein conserved in bacteria
ICDKHGKO_02772 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ICDKHGKO_02773 1.7e-18 S COG0457 FOG TPR repeat
ICDKHGKO_02774 5e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ICDKHGKO_02775 7e-209 iscS 2.8.1.7 E Cysteine desulfurase
ICDKHGKO_02776 2.9e-63 cymR K Transcriptional regulator
ICDKHGKO_02777 7e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
ICDKHGKO_02778 3.3e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
ICDKHGKO_02779 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ICDKHGKO_02780 4.5e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
ICDKHGKO_02783 4.2e-265 lytH 3.5.1.28 M COG3103 SH3 domain protein
ICDKHGKO_02784 2e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ICDKHGKO_02785 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICDKHGKO_02786 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ICDKHGKO_02787 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
ICDKHGKO_02788 2.7e-44 yrvD S Lipopolysaccharide assembly protein A domain
ICDKHGKO_02789 4.6e-80 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
ICDKHGKO_02790 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICDKHGKO_02791 8e-48 yrzD S Post-transcriptional regulator
ICDKHGKO_02792 7.7e-267 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICDKHGKO_02793 5.1e-103 yrbG S membrane
ICDKHGKO_02794 5.3e-60 yrzE S Protein of unknown function (DUF3792)
ICDKHGKO_02795 2.5e-37 yajC U Preprotein translocase subunit YajC
ICDKHGKO_02796 7.5e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ICDKHGKO_02797 2.7e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICDKHGKO_02798 2.8e-20 yrzS S Protein of unknown function (DUF2905)
ICDKHGKO_02799 2.9e-182 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ICDKHGKO_02800 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ICDKHGKO_02801 5.9e-91 bofC S BofC C-terminal domain
ICDKHGKO_02803 4e-26 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ICDKHGKO_02804 2.1e-112 safA M spore coat assembly protein SafA
ICDKHGKO_02805 5.4e-206 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ICDKHGKO_02806 1e-140 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
ICDKHGKO_02807 1.3e-277 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
ICDKHGKO_02808 3.4e-211 nifS 2.8.1.7 E Cysteine desulfurase
ICDKHGKO_02809 2.9e-88 niaR S small molecule binding protein (contains 3H domain)
ICDKHGKO_02810 6.1e-157 pheA 4.2.1.51 E Prephenate dehydratase
ICDKHGKO_02811 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
ICDKHGKO_02812 6.4e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICDKHGKO_02813 4.8e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
ICDKHGKO_02814 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
ICDKHGKO_02815 7e-56 ysxB J ribosomal protein
ICDKHGKO_02816 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
ICDKHGKO_02817 2.3e-156 spoIVFB S Stage IV sporulation protein
ICDKHGKO_02818 3.8e-137 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
ICDKHGKO_02819 2.3e-142 minD D Belongs to the ParA family
ICDKHGKO_02820 2.2e-101 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
ICDKHGKO_02821 1.1e-81 mreD M shape-determining protein
ICDKHGKO_02822 8e-157 mreC M Involved in formation and maintenance of cell shape
ICDKHGKO_02823 1.3e-182 mreB D Rod shape-determining protein MreB
ICDKHGKO_02824 4.5e-126 radC E Belongs to the UPF0758 family
ICDKHGKO_02825 3.8e-99 maf D septum formation protein Maf
ICDKHGKO_02826 2.5e-125 spoIIB S Sporulation related domain
ICDKHGKO_02827 4.6e-124 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
ICDKHGKO_02828 1.2e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ICDKHGKO_02829 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ICDKHGKO_02830 3.1e-24
ICDKHGKO_02831 4.9e-185 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ICDKHGKO_02832 5.7e-150 spoVID M stage VI sporulation protein D
ICDKHGKO_02833 7.1e-242 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
ICDKHGKO_02834 2.1e-182 hemB 4.2.1.24 H Belongs to the ALAD family
ICDKHGKO_02835 1.1e-136 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
ICDKHGKO_02836 1.8e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
ICDKHGKO_02837 3.6e-146 hemX O cytochrome C
ICDKHGKO_02838 2.1e-244 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ICDKHGKO_02839 5.1e-84 ysxD
ICDKHGKO_02840 1.5e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
ICDKHGKO_02841 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ICDKHGKO_02842 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
ICDKHGKO_02843 1.9e-228 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICDKHGKO_02844 7.5e-212 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ICDKHGKO_02845 1e-187 ysoA H Tetratricopeptide repeat
ICDKHGKO_02846 1.3e-113 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ICDKHGKO_02847 2.5e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ICDKHGKO_02848 6.5e-196 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
ICDKHGKO_02849 9e-284 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ICDKHGKO_02850 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ICDKHGKO_02851 3.5e-83 ilvN 2.2.1.6 E Acetolactate synthase
ICDKHGKO_02852 0.0 ilvB 2.2.1.6 E Acetolactate synthase
ICDKHGKO_02857 6.1e-88 ysnB S Phosphoesterase
ICDKHGKO_02858 8e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICDKHGKO_02859 5.8e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ICDKHGKO_02860 3.4e-197 gerM S COG5401 Spore germination protein
ICDKHGKO_02861 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ICDKHGKO_02862 4.1e-72 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
ICDKHGKO_02863 2e-30 gerE K Transcriptional regulator
ICDKHGKO_02864 2.1e-73 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
ICDKHGKO_02865 3.9e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
ICDKHGKO_02866 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
ICDKHGKO_02867 4.8e-108 sdhC C succinate dehydrogenase
ICDKHGKO_02868 3.5e-79 yslB S Protein of unknown function (DUF2507)
ICDKHGKO_02869 1.2e-211 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
ICDKHGKO_02870 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ICDKHGKO_02871 2.5e-52 trxA O Belongs to the thioredoxin family
ICDKHGKO_02872 1.5e-296 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
ICDKHGKO_02873 1.1e-175 etfA C Electron transfer flavoprotein
ICDKHGKO_02874 2.2e-137 etfB C Electron transfer flavoprotein
ICDKHGKO_02875 3.6e-132 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
ICDKHGKO_02876 2.7e-103 fadR K Transcriptional regulator
ICDKHGKO_02877 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
ICDKHGKO_02878 2e-115 ywbB S Protein of unknown function (DUF2711)
ICDKHGKO_02879 4.7e-67 yshE S membrane
ICDKHGKO_02880 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ICDKHGKO_02881 0.0 polX L COG1796 DNA polymerase IV (family X)
ICDKHGKO_02882 2.3e-82 cvpA S membrane protein, required for colicin V production
ICDKHGKO_02883 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ICDKHGKO_02884 1.5e-164 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ICDKHGKO_02885 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICDKHGKO_02886 4e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ICDKHGKO_02887 1e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICDKHGKO_02888 7.6e-32 sspI S Belongs to the SspI family
ICDKHGKO_02889 8.2e-191 ysfB KT regulator
ICDKHGKO_02890 2.8e-252 glcD 1.1.3.15 C FAD binding domain
ICDKHGKO_02891 4.1e-245 glcF C Glycolate oxidase
ICDKHGKO_02892 0.0 cstA T Carbon starvation protein
ICDKHGKO_02893 1.6e-294 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
ICDKHGKO_02894 5.1e-140 araQ G transport system permease
ICDKHGKO_02895 9.6e-164 araP P PFAM binding-protein-dependent transport systems inner membrane component
ICDKHGKO_02896 6.2e-246 araN G carbohydrate transport
ICDKHGKO_02897 7e-212 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
ICDKHGKO_02898 4e-137 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
ICDKHGKO_02899 1.6e-131 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
ICDKHGKO_02900 2.8e-307 araB 2.7.1.16 C Belongs to the ribulokinase family
ICDKHGKO_02901 1.5e-291 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
ICDKHGKO_02902 1e-184 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
ICDKHGKO_02903 4e-206 ysdC G COG1363 Cellulase M and related proteins
ICDKHGKO_02904 2.6e-62 ysdB S Sigma-w pathway protein YsdB
ICDKHGKO_02905 1e-38 ysdA S Membrane
ICDKHGKO_02906 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICDKHGKO_02907 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
ICDKHGKO_02908 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICDKHGKO_02909 2.7e-107 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
ICDKHGKO_02910 3.6e-36 lrgA S effector of murein hydrolase LrgA
ICDKHGKO_02911 1e-128 lytT T COG3279 Response regulator of the LytR AlgR family
ICDKHGKO_02912 0.0 lytS 2.7.13.3 T Histidine kinase
ICDKHGKO_02913 4.1e-147 ysaA S HAD-hyrolase-like
ICDKHGKO_02914 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ICDKHGKO_02915 1.6e-149 ytxC S YtxC-like family
ICDKHGKO_02916 1.8e-105 ytxB S SNARE associated Golgi protein
ICDKHGKO_02917 2.9e-168 dnaI L Primosomal protein DnaI
ICDKHGKO_02918 7.7e-250 dnaB L Membrane attachment protein
ICDKHGKO_02919 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ICDKHGKO_02920 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ICDKHGKO_02921 1.3e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ICDKHGKO_02922 1.6e-64 ytcD K Transcriptional regulator
ICDKHGKO_02923 6.9e-199 ytbD EGP Major facilitator Superfamily
ICDKHGKO_02924 1.5e-155 ytbE S reductase
ICDKHGKO_02925 3.9e-94 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ICDKHGKO_02926 2.6e-104 ytaF P Probably functions as a manganese efflux pump
ICDKHGKO_02927 2.7e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ICDKHGKO_02928 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICDKHGKO_02929 2.6e-308 phoR 2.7.13.3 T Signal transduction histidine kinase
ICDKHGKO_02930 5e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICDKHGKO_02931 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
ICDKHGKO_02932 2e-241 icd 1.1.1.42 C isocitrate
ICDKHGKO_02933 8.1e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
ICDKHGKO_02934 1.5e-72 yeaL S membrane
ICDKHGKO_02935 1.8e-193 ytvI S sporulation integral membrane protein YtvI
ICDKHGKO_02936 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
ICDKHGKO_02937 1.2e-292 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
ICDKHGKO_02938 9.8e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
ICDKHGKO_02939 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
ICDKHGKO_02940 6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICDKHGKO_02941 5.9e-222 ytsJ 1.1.1.38 C Malate dehydrogenase
ICDKHGKO_02942 0.0 dnaE 2.7.7.7 L DNA polymerase
ICDKHGKO_02943 3.9e-54 ytrH S Sporulation protein YtrH
ICDKHGKO_02944 5.6e-86 ytrI
ICDKHGKO_02945 6.4e-22
ICDKHGKO_02946 2.9e-176 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
ICDKHGKO_02947 3.8e-45 ytpI S YtpI-like protein
ICDKHGKO_02948 6.8e-238 ytoI K transcriptional regulator containing CBS domains
ICDKHGKO_02949 1.1e-127 ytkL S Belongs to the UPF0173 family
ICDKHGKO_02950 3.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICDKHGKO_02952 6.1e-260 argH 4.3.2.1 E argininosuccinate lyase
ICDKHGKO_02953 4.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
ICDKHGKO_02954 8e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
ICDKHGKO_02955 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICDKHGKO_02956 9.7e-175 ytxK 2.1.1.72 L DNA methylase
ICDKHGKO_02957 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ICDKHGKO_02958 1.5e-63 ytfJ S Sporulation protein YtfJ
ICDKHGKO_02959 4.1e-111 ytfI S Protein of unknown function (DUF2953)
ICDKHGKO_02960 4.5e-80 yteJ S RDD family
ICDKHGKO_02961 1.4e-176 sppA OU signal peptide peptidase SppA
ICDKHGKO_02962 5.9e-149 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ICDKHGKO_02963 8.3e-301 ytcJ S amidohydrolase
ICDKHGKO_02964 9.1e-300 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
ICDKHGKO_02965 6.6e-31 sspB S spore protein
ICDKHGKO_02966 1.4e-220 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICDKHGKO_02967 3.4e-203 iscS2 2.8.1.7 E Cysteine desulfurase
ICDKHGKO_02968 6.4e-238 braB E Component of the transport system for branched-chain amino acids
ICDKHGKO_02969 2.3e-261 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ICDKHGKO_02970 4.3e-144 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
ICDKHGKO_02971 7.9e-106 yttP K Transcriptional regulator
ICDKHGKO_02972 8.6e-84 ytsP 1.8.4.14 T GAF domain-containing protein
ICDKHGKO_02973 4.6e-268 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
ICDKHGKO_02974 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICDKHGKO_02975 2.2e-213 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICDKHGKO_02978 1.3e-08 yhbO 1.11.1.6, 3.5.1.124 S protease
ICDKHGKO_02980 2.9e-126 E GDSL-like Lipase/Acylhydrolase family
ICDKHGKO_02981 5.8e-147 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ICDKHGKO_02982 5.4e-147 K Transcriptional regulator
ICDKHGKO_02983 1.9e-119 azlC E AzlC protein
ICDKHGKO_02984 7.4e-47 azlD S Branched-chain amino acid transport protein (AzlD)
ICDKHGKO_02985 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ICDKHGKO_02986 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
ICDKHGKO_02987 6.3e-119 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
ICDKHGKO_02988 2e-107 acuB S Domain in cystathionine beta-synthase and other proteins.
ICDKHGKO_02989 7.9e-224 acuC BQ histone deacetylase
ICDKHGKO_02990 4.1e-111 motS N Flagellar motor protein
ICDKHGKO_02991 4.8e-143 motA N flagellar motor
ICDKHGKO_02992 3.9e-179 ccpA K catabolite control protein A
ICDKHGKO_02993 1.6e-194 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
ICDKHGKO_02994 2.2e-43 ytxJ O Protein of unknown function (DUF2847)
ICDKHGKO_02995 1.7e-16 ytxH S COG4980 Gas vesicle protein
ICDKHGKO_02996 8.2e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ICDKHGKO_02997 7.1e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
ICDKHGKO_02998 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
ICDKHGKO_02999 5.9e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ICDKHGKO_03000 3e-145 ytpQ S Belongs to the UPF0354 family
ICDKHGKO_03001 3.5e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ICDKHGKO_03002 1.8e-75 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
ICDKHGKO_03003 4.1e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
ICDKHGKO_03004 1.7e-51 ytzB S small secreted protein
ICDKHGKO_03005 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
ICDKHGKO_03006 3.4e-160 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
ICDKHGKO_03007 1.5e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ICDKHGKO_03008 1.3e-44 ytzH S YtzH-like protein
ICDKHGKO_03009 4.1e-155 ytmP 2.7.1.89 M Phosphotransferase
ICDKHGKO_03010 2.6e-169 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
ICDKHGKO_03011 5.1e-141 ytlQ
ICDKHGKO_03012 2.4e-98 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ICDKHGKO_03013 1.6e-166 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ICDKHGKO_03014 6.2e-260 pepV 3.5.1.18 E Dipeptidase
ICDKHGKO_03015 5.5e-226 pbuO S permease
ICDKHGKO_03016 2.5e-198 ythQ U Bacterial ABC transporter protein EcsB
ICDKHGKO_03017 1.9e-116 ythP V ABC transporter
ICDKHGKO_03018 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
ICDKHGKO_03019 2e-124 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ICDKHGKO_03020 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICDKHGKO_03021 5.5e-231 ytfP S HI0933-like protein
ICDKHGKO_03022 1.4e-276 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
ICDKHGKO_03023 2.6e-25 yteV S Sporulation protein Cse60
ICDKHGKO_03024 7.2e-181 msmR K Transcriptional regulator
ICDKHGKO_03025 4.1e-234 msmE G Bacterial extracellular solute-binding protein
ICDKHGKO_03026 5.5e-164 amyD G Binding-protein-dependent transport system inner membrane component
ICDKHGKO_03027 1.5e-141 amyC P ABC transporter (permease)
ICDKHGKO_03028 8.1e-246 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
ICDKHGKO_03029 1.1e-73 M Acetyltransferase (GNAT) domain
ICDKHGKO_03030 1.3e-51 ytwF P Sulfurtransferase
ICDKHGKO_03031 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ICDKHGKO_03032 1.2e-52 ytvB S Protein of unknown function (DUF4257)
ICDKHGKO_03033 3.5e-135 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
ICDKHGKO_03034 4.9e-205 yttB EGP Major facilitator Superfamily
ICDKHGKO_03035 4e-102 ywaF S Integral membrane protein
ICDKHGKO_03036 0.0 bceB V ABC transporter (permease)
ICDKHGKO_03037 2.7e-132 bceA V ABC transporter, ATP-binding protein
ICDKHGKO_03038 5.4e-154 T PhoQ Sensor
ICDKHGKO_03039 1.1e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICDKHGKO_03040 5.8e-199 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
ICDKHGKO_03041 1.1e-124 ytrE V ABC transporter, ATP-binding protein
ICDKHGKO_03042 1.1e-144
ICDKHGKO_03043 7.8e-148 P ABC-2 family transporter protein
ICDKHGKO_03044 1.9e-162 S ABC-2 family transporter protein
ICDKHGKO_03045 1.4e-156 ytrB P abc transporter atp-binding protein
ICDKHGKO_03046 4.3e-65 ytrA K GntR family transcriptional regulator
ICDKHGKO_03048 8.1e-39 ytzC S Protein of unknown function (DUF2524)
ICDKHGKO_03049 1.4e-189 yhcC S Fe-S oxidoreductase
ICDKHGKO_03050 3.4e-103 ytqB J Putative rRNA methylase
ICDKHGKO_03052 7.3e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
ICDKHGKO_03053 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
ICDKHGKO_03054 1.8e-55 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ICDKHGKO_03055 8.5e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
ICDKHGKO_03056 0.0 asnB 6.3.5.4 E Asparagine synthase
ICDKHGKO_03057 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ICDKHGKO_03058 2.6e-302 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ICDKHGKO_03059 8e-38 ytmB S Protein of unknown function (DUF2584)
ICDKHGKO_03060 2.2e-145 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
ICDKHGKO_03061 1.9e-178 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
ICDKHGKO_03062 1.5e-141 ytlC P ABC transporter
ICDKHGKO_03063 3.8e-124 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
ICDKHGKO_03064 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
ICDKHGKO_03065 1.2e-59 ytkC S Bacteriophage holin family
ICDKHGKO_03066 7.8e-76 dps P Belongs to the Dps family
ICDKHGKO_03068 6.7e-75 ytkA S YtkA-like
ICDKHGKO_03069 2.2e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ICDKHGKO_03070 2e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
ICDKHGKO_03071 1.3e-102 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
ICDKHGKO_03072 7.9e-41 rpmE2 J Ribosomal protein L31
ICDKHGKO_03073 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
ICDKHGKO_03074 1.9e-181 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
ICDKHGKO_03075 4e-24 S Domain of Unknown Function (DUF1540)
ICDKHGKO_03076 2e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
ICDKHGKO_03077 1.7e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
ICDKHGKO_03078 7.9e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ICDKHGKO_03079 1.9e-147 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
ICDKHGKO_03080 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ICDKHGKO_03081 3.7e-260 menF 5.4.4.2 HQ Isochorismate synthase
ICDKHGKO_03082 2.3e-125 dksA T COG1734 DnaK suppressor protein
ICDKHGKO_03083 4.8e-71 tspO T membrane
ICDKHGKO_03092 7.8e-08
ICDKHGKO_03093 1.3e-09
ICDKHGKO_03100 1.6e-08
ICDKHGKO_03105 2.2e-38 S COG NOG14552 non supervised orthologous group
ICDKHGKO_03106 2.7e-92 thiT S Thiamine transporter protein (Thia_YuaJ)
ICDKHGKO_03107 6.1e-176 yuaG 3.4.21.72 S protein conserved in bacteria
ICDKHGKO_03108 2.6e-81 yuaF OU Membrane protein implicated in regulation of membrane protease activity
ICDKHGKO_03109 2.2e-79 yuaE S DinB superfamily
ICDKHGKO_03110 1.2e-103 yuaD S MOSC domain
ICDKHGKO_03111 6.7e-226 gbsB 1.1.1.1 C alcohol dehydrogenase
ICDKHGKO_03112 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
ICDKHGKO_03113 3.4e-92 yuaC K Belongs to the GbsR family
ICDKHGKO_03114 4.3e-92 yuaB
ICDKHGKO_03115 1.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
ICDKHGKO_03116 9.3e-142 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICDKHGKO_03117 5.2e-207 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICDKHGKO_03118 1.7e-36 G Cupin
ICDKHGKO_03119 1.1e-42 yjcN
ICDKHGKO_03122 2.4e-132 S Aspartate phosphatase response regulator
ICDKHGKO_03123 4e-14
ICDKHGKO_03124 4.8e-100 K Helix-turn-helix domain
ICDKHGKO_03125 3.1e-14 K Transcriptional regulator
ICDKHGKO_03126 2.5e-13 S YolD-like protein
ICDKHGKO_03127 4.9e-53
ICDKHGKO_03128 9.7e-34 S Bacteriophage A118-like holin, Hol118
ICDKHGKO_03129 2e-145 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
ICDKHGKO_03130 4.5e-29 S BhlA holin family
ICDKHGKO_03132 1.7e-12
ICDKHGKO_03133 1.6e-85
ICDKHGKO_03134 0.0 M Pectate lyase superfamily protein
ICDKHGKO_03135 5.9e-187 L Prophage endopeptidase tail
ICDKHGKO_03136 1e-108 S Phage tail protein
ICDKHGKO_03137 8.8e-124 D Phage tail tape measure protein
ICDKHGKO_03138 4.9e-33
ICDKHGKO_03139 3e-70 N phage major tail protein, phi13 family
ICDKHGKO_03140 3.8e-25
ICDKHGKO_03142 8.1e-36 S Phage head-tail joining protein
ICDKHGKO_03143 4.5e-25 S Phage gp6-like head-tail connector protein
ICDKHGKO_03144 5.2e-28 N domain, Protein
ICDKHGKO_03145 1.1e-169 S Phage capsid family
ICDKHGKO_03146 3.6e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
ICDKHGKO_03147 6.5e-227 S Phage portal protein
ICDKHGKO_03148 0.0 S Terminase
ICDKHGKO_03149 3.4e-44 L Phage terminase, small subunit
ICDKHGKO_03150 1.7e-30 L HNH endonuclease
ICDKHGKO_03151 3.8e-40
ICDKHGKO_03153 1.6e-34
ICDKHGKO_03155 5.2e-07
ICDKHGKO_03158 2e-42 epsH GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
ICDKHGKO_03159 1.1e-28 K Cro/C1-type HTH DNA-binding domain
ICDKHGKO_03160 1e-57 S Pfam:DUF867
ICDKHGKO_03161 3.6e-119 3.2.1.15 M Right handed beta helix region
ICDKHGKO_03165 1.9e-45
ICDKHGKO_03166 9.2e-23
ICDKHGKO_03167 2.8e-25 S Helix-turn-helix domain
ICDKHGKO_03168 7.3e-12
ICDKHGKO_03169 1.1e-35
ICDKHGKO_03170 3.5e-43 K Sigma-70, region 4
ICDKHGKO_03171 2.6e-20 S HNH endonuclease
ICDKHGKO_03173 3.6e-171 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
ICDKHGKO_03174 2.3e-75 2.7.1.24 H dephospho-CoA kinase activity
ICDKHGKO_03175 1.2e-40
ICDKHGKO_03177 1.6e-33 S protein conserved in bacteria
ICDKHGKO_03178 1.8e-98 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
ICDKHGKO_03180 3.5e-57 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
ICDKHGKO_03182 2.2e-150 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICDKHGKO_03184 8.6e-183 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICDKHGKO_03185 3.1e-24 L GIY-YIG catalytic domain
ICDKHGKO_03186 2.4e-123 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICDKHGKO_03187 5.5e-43 nrdI 1.17.4.1 F Belongs to the NrdI family
ICDKHGKO_03190 4.4e-16 S Protein of unknown function (DUF1523)
ICDKHGKO_03191 5e-32 3.1.22.4 S Crossover junction endodeoxyribonuclease RuvC
ICDKHGKO_03193 3.4e-165
ICDKHGKO_03194 4.2e-103 2.7.7.7 L EXOIII
ICDKHGKO_03195 2.4e-194 L DNA polymerase A domain
ICDKHGKO_03197 5.9e-23
ICDKHGKO_03198 1.1e-48
ICDKHGKO_03199 2.2e-81
ICDKHGKO_03203 1.7e-15
ICDKHGKO_03205 7.1e-66
ICDKHGKO_03206 3.9e-08 K Cro/C1-type HTH DNA-binding domain
ICDKHGKO_03207 1.6e-129 dnaG L Toprim-like
ICDKHGKO_03208 6.2e-143 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
ICDKHGKO_03209 1e-24
ICDKHGKO_03210 4.5e-09 yodN
ICDKHGKO_03211 7.3e-109 L DNA-dependent DNA replication
ICDKHGKO_03214 6.7e-65
ICDKHGKO_03215 3.1e-22
ICDKHGKO_03216 6e-25
ICDKHGKO_03218 1.3e-38 S Helix-turn-helix domain
ICDKHGKO_03220 6.7e-89 L Belongs to the 'phage' integrase family
ICDKHGKO_03222 2.8e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
ICDKHGKO_03223 5.5e-193 yubA S transporter activity
ICDKHGKO_03224 9.1e-181 ygjR S Oxidoreductase
ICDKHGKO_03225 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
ICDKHGKO_03226 6.9e-228 mcpA NT chemotaxis protein
ICDKHGKO_03227 2.2e-218 mcpA NT chemotaxis protein
ICDKHGKO_03228 1.3e-213 mcpA NT chemotaxis protein
ICDKHGKO_03229 5.5e-209 mcpA NT chemotaxis protein
ICDKHGKO_03230 3.3e-135 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
ICDKHGKO_03231 5.8e-39
ICDKHGKO_03232 3.6e-186 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
ICDKHGKO_03233 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
ICDKHGKO_03234 8.1e-230 yugS S COG1253 Hemolysins and related proteins containing CBS domains
ICDKHGKO_03235 4.1e-116 yugP S Zn-dependent protease
ICDKHGKO_03236 6.5e-17
ICDKHGKO_03237 1e-27 mstX S Membrane-integrating protein Mistic
ICDKHGKO_03238 1.6e-177 yugO P COG1226 Kef-type K transport systems
ICDKHGKO_03239 5e-69 yugN S YugN-like family
ICDKHGKO_03241 2.1e-257 pgi 5.3.1.9 G Belongs to the GPI family
ICDKHGKO_03242 5.8e-227 yugK C Dehydrogenase
ICDKHGKO_03243 1e-223 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
ICDKHGKO_03244 6.8e-34 yuzA S Domain of unknown function (DUF378)
ICDKHGKO_03245 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
ICDKHGKO_03246 3e-207 yugH 2.6.1.1 E Aminotransferase
ICDKHGKO_03247 5.8e-83 alaR K Transcriptional regulator
ICDKHGKO_03248 2e-149 yugF I Hydrolase
ICDKHGKO_03249 5e-38 yugE S Domain of unknown function (DUF1871)
ICDKHGKO_03250 9.9e-219 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
ICDKHGKO_03251 2.9e-219 T PhoQ Sensor
ICDKHGKO_03252 7.4e-62 kapB G Kinase associated protein B
ICDKHGKO_03253 4.7e-115 kapD L the KinA pathway to sporulation
ICDKHGKO_03254 1.5e-165 yuxJ EGP Major facilitator Superfamily
ICDKHGKO_03255 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
ICDKHGKO_03256 1e-69 yuxK S protein conserved in bacteria
ICDKHGKO_03257 1.1e-71 yufK S Family of unknown function (DUF5366)
ICDKHGKO_03258 3.5e-291 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
ICDKHGKO_03259 8.7e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
ICDKHGKO_03260 5.1e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
ICDKHGKO_03261 1.7e-279 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
ICDKHGKO_03262 7.4e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
ICDKHGKO_03263 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
ICDKHGKO_03264 9.8e-11
ICDKHGKO_03265 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
ICDKHGKO_03266 6.6e-67 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ICDKHGKO_03267 2.2e-49 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ICDKHGKO_03268 8.1e-258 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ICDKHGKO_03269 5.5e-75 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ICDKHGKO_03270 1.4e-36 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ICDKHGKO_03271 9.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
ICDKHGKO_03272 2.6e-59 ydiI Q protein, possibly involved in aromatic compounds catabolism
ICDKHGKO_03273 6.9e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICDKHGKO_03274 4.2e-253 comP 2.7.13.3 T Histidine kinase
ICDKHGKO_03276 2.9e-61 comQ H Belongs to the FPP GGPP synthase family
ICDKHGKO_03278 1.6e-47 yuzC
ICDKHGKO_03279 8.2e-224 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
ICDKHGKO_03280 2.8e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ICDKHGKO_03281 3e-101 pncA Q COG1335 Amidases related to nicotinamidase
ICDKHGKO_03282 1.1e-65 yueI S Protein of unknown function (DUF1694)
ICDKHGKO_03283 4.8e-38 yueH S YueH-like protein
ICDKHGKO_03284 7.1e-33 yueG S Spore germination protein gerPA/gerPF
ICDKHGKO_03285 4.1e-182 yueF S transporter activity
ICDKHGKO_03286 1.6e-22 S Protein of unknown function (DUF2642)
ICDKHGKO_03287 2.4e-95 yueE S phosphohydrolase
ICDKHGKO_03288 3.4e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICDKHGKO_03289 2.7e-74 yueC S Family of unknown function (DUF5383)
ICDKHGKO_03290 0.0 esaA S type VII secretion protein EsaA
ICDKHGKO_03291 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
ICDKHGKO_03292 6.3e-198 essB S WXG100 protein secretion system (Wss), protein YukC
ICDKHGKO_03293 9.6e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
ICDKHGKO_03294 1.7e-45 esxA S Belongs to the WXG100 family
ICDKHGKO_03295 6.8e-226 yukF QT Transcriptional regulator
ICDKHGKO_03296 1.3e-202 ald 1.4.1.1 E Belongs to the AlaDH PNT family
ICDKHGKO_03297 1.9e-129 yukJ S Uncharacterized conserved protein (DUF2278)
ICDKHGKO_03298 1.7e-31 mbtH S MbtH-like protein
ICDKHGKO_03299 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICDKHGKO_03300 2.3e-162 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
ICDKHGKO_03301 3.6e-307 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
ICDKHGKO_03302 5.8e-214 entC 5.4.4.2 HQ Isochorismate synthase
ICDKHGKO_03303 2.2e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ICDKHGKO_03304 8.9e-156 besA S Putative esterase
ICDKHGKO_03305 3e-118 yuiH S Oxidoreductase molybdopterin binding domain
ICDKHGKO_03306 1.2e-100 bioY S Biotin biosynthesis protein
ICDKHGKO_03307 1.5e-207 yuiF S antiporter
ICDKHGKO_03308 1.2e-277 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ICDKHGKO_03309 6.5e-76 yuiD S protein conserved in bacteria
ICDKHGKO_03310 1.3e-114 yuiC S protein conserved in bacteria
ICDKHGKO_03311 4.9e-27 yuiB S Putative membrane protein
ICDKHGKO_03312 1.1e-233 yumB 1.6.99.3 C NADH dehydrogenase
ICDKHGKO_03313 1.8e-184 yumC 1.18.1.2, 1.19.1.1 C reductase
ICDKHGKO_03315 3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ICDKHGKO_03316 2e-27
ICDKHGKO_03317 1.4e-66 CP Membrane
ICDKHGKO_03318 3.5e-118 V ABC transporter
ICDKHGKO_03320 4.2e-28 S Bacteriocin class IId cyclical uberolysin-like
ICDKHGKO_03322 6.6e-42 rimJ 2.3.1.128 J Alanine acetyltransferase
ICDKHGKO_03323 1.3e-129 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
ICDKHGKO_03324 2.6e-61 erpA S Belongs to the HesB IscA family
ICDKHGKO_03325 3.8e-159 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ICDKHGKO_03326 3.6e-203 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICDKHGKO_03327 1.7e-37 yuzB S Belongs to the UPF0349 family
ICDKHGKO_03328 5.7e-205 yutJ 1.6.99.3 C NADH dehydrogenase
ICDKHGKO_03329 4.1e-53 yuzD S protein conserved in bacteria
ICDKHGKO_03330 1.6e-35 yutI O COG0694 Thioredoxin-like proteins and domains
ICDKHGKO_03331 3.9e-252 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
ICDKHGKO_03332 8.1e-54 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
ICDKHGKO_03333 3.1e-162 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ICDKHGKO_03334 4.5e-194 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ICDKHGKO_03335 5.1e-240 hom 1.1.1.3 E homoserine dehydrogenase
ICDKHGKO_03336 6.3e-193 yutH S Spore coat protein
ICDKHGKO_03337 3.4e-83 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
ICDKHGKO_03338 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ICDKHGKO_03339 8.9e-72 yutE S Protein of unknown function DUF86
ICDKHGKO_03340 1.7e-47 yutD S protein conserved in bacteria
ICDKHGKO_03341 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ICDKHGKO_03342 2.5e-191 lytH M Peptidase, M23
ICDKHGKO_03343 1.1e-128 yunB S Sporulation protein YunB (Spo_YunB)
ICDKHGKO_03344 1.2e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
ICDKHGKO_03345 4.8e-143 yunE S membrane transporter protein
ICDKHGKO_03346 9.9e-168 yunF S Protein of unknown function DUF72
ICDKHGKO_03347 2.1e-55 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
ICDKHGKO_03348 2.7e-252 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
ICDKHGKO_03349 1.7e-293 pucR QT COG2508 Regulator of polyketide synthase expression
ICDKHGKO_03350 2.8e-65
ICDKHGKO_03351 1.4e-207 blt EGP Major facilitator Superfamily
ICDKHGKO_03352 1.2e-225 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
ICDKHGKO_03353 6.4e-224 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
ICDKHGKO_03354 3.7e-162 bsn L Ribonuclease
ICDKHGKO_03355 7e-198 msmX P Belongs to the ABC transporter superfamily
ICDKHGKO_03356 1.5e-132 yurK K UTRA
ICDKHGKO_03357 2.5e-158 yurL 2.7.1.218 G pfkB family carbohydrate kinase
ICDKHGKO_03358 2.4e-156 yurM P COG0395 ABC-type sugar transport system, permease component
ICDKHGKO_03359 2.2e-157 yurN G Binding-protein-dependent transport system inner membrane component
ICDKHGKO_03360 2.1e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
ICDKHGKO_03361 5.3e-181 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
ICDKHGKO_03362 8.3e-160 K helix_turn_helix, mercury resistance
ICDKHGKO_03363 1e-14
ICDKHGKO_03364 5.3e-77
ICDKHGKO_03365 2.1e-22 S Sporulation delaying protein SdpA
ICDKHGKO_03367 2.6e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
ICDKHGKO_03368 3.5e-197 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
ICDKHGKO_03369 3.4e-101 Q ubiE/COQ5 methyltransferase family
ICDKHGKO_03370 1.1e-72 yncE S Protein of unknown function (DUF2691)
ICDKHGKO_03371 1.9e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
ICDKHGKO_03372 8.7e-270 sufB O FeS cluster assembly
ICDKHGKO_03373 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
ICDKHGKO_03374 2.8e-232 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICDKHGKO_03375 7e-245 sufD O assembly protein SufD
ICDKHGKO_03376 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
ICDKHGKO_03377 6.7e-09
ICDKHGKO_03378 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICDKHGKO_03379 4e-142 metQ P Belongs to the NlpA lipoprotein family
ICDKHGKO_03380 8.3e-93 metI P COG2011 ABC-type metal ion transport system, permease component
ICDKHGKO_03381 1.1e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ICDKHGKO_03382 2.1e-55 yusD S SCP-2 sterol transfer family
ICDKHGKO_03383 5.2e-53 yusE CO Thioredoxin
ICDKHGKO_03384 9.7e-22 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
ICDKHGKO_03385 2.1e-38 yusG S Protein of unknown function (DUF2553)
ICDKHGKO_03386 5.5e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
ICDKHGKO_03387 1.8e-62 arsC 1.20.4.1 P Belongs to the ArsC family
ICDKHGKO_03388 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
ICDKHGKO_03389 1e-215 fadA 2.3.1.16 I Belongs to the thiolase family
ICDKHGKO_03390 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
ICDKHGKO_03392 3.9e-162 fadM E Proline dehydrogenase
ICDKHGKO_03393 3.5e-39
ICDKHGKO_03394 1.3e-51 yusN M Coat F domain
ICDKHGKO_03395 4.5e-66 yusO K Iron dependent repressor, N-terminal DNA binding domain
ICDKHGKO_03396 5.4e-284 yusP P Major facilitator superfamily
ICDKHGKO_03397 9.8e-59 L PFAM Restriction endonuclease BamHI
ICDKHGKO_03398 1.8e-16 K Helix-turn-helix XRE-family like proteins
ICDKHGKO_03399 2.2e-126 2.1.1.72 L DNA methylase
ICDKHGKO_03400 8.1e-38 yusU S Protein of unknown function (DUF2573)
ICDKHGKO_03401 3.1e-150 yusV 3.6.3.34 HP ABC transporter
ICDKHGKO_03402 1e-46 S YusW-like protein
ICDKHGKO_03403 0.0 pepF2 E COG1164 Oligoendopeptidase F
ICDKHGKO_03404 3.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ICDKHGKO_03405 1.5e-77 dps P Belongs to the Dps family
ICDKHGKO_03406 3.5e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICDKHGKO_03407 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICDKHGKO_03408 6.3e-249 cssS 2.7.13.3 T PhoQ Sensor
ICDKHGKO_03409 1.3e-23
ICDKHGKO_03410 3e-154 yuxN K Transcriptional regulator
ICDKHGKO_03411 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ICDKHGKO_03412 6.6e-24 S Protein of unknown function (DUF3970)
ICDKHGKO_03413 1.1e-254 gerAA EG Spore germination protein
ICDKHGKO_03414 4.6e-181 gerAB E Spore germination protein
ICDKHGKO_03415 7.6e-192 gerAC S Spore germination B3/ GerAC like, C-terminal
ICDKHGKO_03416 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICDKHGKO_03417 1.1e-192 vraS 2.7.13.3 T Histidine kinase
ICDKHGKO_03418 4.4e-124 yvqF S Cell wall-active antibiotics response 4TMS YvqF
ICDKHGKO_03419 2.1e-117 liaG S Putative adhesin
ICDKHGKO_03420 8.7e-90 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
ICDKHGKO_03421 6.9e-44 liaI S membrane
ICDKHGKO_03422 1.2e-220 yvqJ EGP Major facilitator Superfamily
ICDKHGKO_03423 2.3e-96 yvqK 2.5.1.17 S Adenosyltransferase
ICDKHGKO_03424 1.2e-201 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
ICDKHGKO_03425 1.4e-176 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICDKHGKO_03426 1.1e-164 yvrC P ABC transporter substrate-binding protein
ICDKHGKO_03427 1e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ICDKHGKO_03428 4.3e-166 yvrE G SMP-30/Gluconolaconase/LRE-like region
ICDKHGKO_03429 0.0 T PhoQ Sensor
ICDKHGKO_03430 5.7e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICDKHGKO_03431 6.2e-35
ICDKHGKO_03432 2.1e-100 yvrI K RNA polymerase
ICDKHGKO_03433 1.6e-15 S YvrJ protein family
ICDKHGKO_03434 3.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
ICDKHGKO_03435 9.9e-60 yvrL S Regulatory protein YrvL
ICDKHGKO_03436 4.5e-146 fhuC 3.6.3.34 HP ABC transporter
ICDKHGKO_03437 1.4e-168 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICDKHGKO_03438 1.5e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICDKHGKO_03439 5.8e-177 fhuD P ABC transporter
ICDKHGKO_03440 4e-122 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ICDKHGKO_03441 3e-233 yvsH E Arginine ornithine antiporter
ICDKHGKO_03442 5.2e-13 S Small spore protein J (Spore_SspJ)
ICDKHGKO_03443 3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
ICDKHGKO_03444 3e-166 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ICDKHGKO_03445 3.5e-163 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ICDKHGKO_03446 5.4e-159 yvgK P COG1910 Periplasmic molybdate-binding protein domain
ICDKHGKO_03447 4.2e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
ICDKHGKO_03448 1.2e-99 modB P COG4149 ABC-type molybdate transport system, permease component
ICDKHGKO_03449 3.3e-113 yfiK K Regulator
ICDKHGKO_03450 5.6e-171 T Histidine kinase
ICDKHGKO_03451 6.8e-170 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
ICDKHGKO_03452 3e-185 yfiM V ABC-2 type transporter
ICDKHGKO_03453 7.3e-174 yfiN V COG0842 ABC-type multidrug transport system, permease component
ICDKHGKO_03454 5e-156 yvgN S reductase
ICDKHGKO_03455 2.3e-84 yvgO
ICDKHGKO_03456 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
ICDKHGKO_03457 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
ICDKHGKO_03458 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ICDKHGKO_03459 0.0 helD 3.6.4.12 L DNA helicase
ICDKHGKO_03461 1e-97 yvgT S membrane
ICDKHGKO_03462 9.1e-139 S Metallo-peptidase family M12
ICDKHGKO_03463 8.6e-72 bdbC O Required for disulfide bond formation in some proteins
ICDKHGKO_03464 7.7e-99 bdbD O Thioredoxin
ICDKHGKO_03465 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
ICDKHGKO_03466 0.0 copA 3.6.3.54 P P-type ATPase
ICDKHGKO_03467 9.9e-29 copZ P Heavy-metal-associated domain
ICDKHGKO_03468 1.4e-47 csoR S transcriptional
ICDKHGKO_03469 8.9e-187 yvaA 1.1.1.371 S Oxidoreductase
ICDKHGKO_03470 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICDKHGKO_03471 5.6e-250 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICDKHGKO_03472 1e-44 ytnI O COG0695 Glutaredoxin and related proteins
ICDKHGKO_03473 9.1e-176 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICDKHGKO_03474 2.2e-137 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ICDKHGKO_03475 5.1e-117 tcyM U Binding-protein-dependent transport system inner membrane component
ICDKHGKO_03476 2.1e-118 tcyL P Binding-protein-dependent transport system inner membrane component
ICDKHGKO_03477 2.4e-131 tcyK M Bacterial periplasmic substrate-binding proteins
ICDKHGKO_03478 1.7e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
ICDKHGKO_03479 2.5e-100 ytmI K Acetyltransferase (GNAT) domain
ICDKHGKO_03480 2.2e-157 ytlI K LysR substrate binding domain
ICDKHGKO_03481 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ICDKHGKO_03482 1.8e-42 yrdF K ribonuclease inhibitor
ICDKHGKO_03484 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ICDKHGKO_03485 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ICDKHGKO_03486 1.6e-142 est 3.1.1.1 S Carboxylesterase
ICDKHGKO_03487 4.2e-20 secG U Preprotein translocase subunit SecG
ICDKHGKO_03488 6e-35 yvzC K Transcriptional
ICDKHGKO_03489 1.6e-67 K transcriptional
ICDKHGKO_03490 9.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
ICDKHGKO_03491 1.4e-50 yodB K transcriptional
ICDKHGKO_03492 6.5e-241 T His Kinase A (phosphoacceptor) domain
ICDKHGKO_03493 1.3e-119 K Transcriptional regulatory protein, C terminal
ICDKHGKO_03494 3.2e-133 mutG S ABC-2 family transporter protein
ICDKHGKO_03495 1.3e-120 spaE S ABC-2 family transporter protein
ICDKHGKO_03496 1.3e-125 mutF V ABC transporter, ATP-binding protein
ICDKHGKO_03497 9.8e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
ICDKHGKO_03498 5.1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ICDKHGKO_03499 1e-108 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
ICDKHGKO_03500 5.6e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
ICDKHGKO_03501 1.7e-56 yvbF K Belongs to the GbsR family
ICDKHGKO_03502 4.1e-108 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
ICDKHGKO_03503 7.4e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ICDKHGKO_03504 8.6e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
ICDKHGKO_03505 9.7e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
ICDKHGKO_03506 2.8e-94 yvbF K Belongs to the GbsR family
ICDKHGKO_03507 4.4e-104 yvbG U UPF0056 membrane protein
ICDKHGKO_03508 2.6e-113 exoY M Membrane
ICDKHGKO_03509 0.0 tcaA S response to antibiotic
ICDKHGKO_03510 1.4e-78 yvbK 3.1.3.25 K acetyltransferase
ICDKHGKO_03511 7.8e-206 EGP Major facilitator Superfamily
ICDKHGKO_03512 4.2e-172
ICDKHGKO_03513 2e-123 S GlcNAc-PI de-N-acetylase
ICDKHGKO_03514 2.4e-141 C WbqC-like protein family
ICDKHGKO_03515 8.3e-141 M Protein involved in cellulose biosynthesis
ICDKHGKO_03516 1.3e-219 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ICDKHGKO_03517 1.4e-167 5.1.3.2 M GDP-mannose 4,6 dehydratase
ICDKHGKO_03518 7.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
ICDKHGKO_03519 9.5e-250 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ICDKHGKO_03520 7.3e-223 ywaD 3.4.11.10, 3.4.11.6 S PA domain
ICDKHGKO_03521 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ICDKHGKO_03522 6.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
ICDKHGKO_03523 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ICDKHGKO_03524 1.6e-216 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
ICDKHGKO_03525 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ICDKHGKO_03526 8.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
ICDKHGKO_03527 2.3e-31 araE EGP Major facilitator Superfamily
ICDKHGKO_03528 2.8e-211 araE EGP Major facilitator Superfamily
ICDKHGKO_03529 6.7e-201 araR K transcriptional
ICDKHGKO_03530 1.2e-188 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICDKHGKO_03531 1.1e-13 yvbU K Transcriptional regulator
ICDKHGKO_03532 1.7e-96 yvbU K Transcriptional regulator
ICDKHGKO_03533 2.8e-152 yvbV EG EamA-like transporter family
ICDKHGKO_03534 3.2e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
ICDKHGKO_03536 6.7e-148 ybbH_1 K RpiR family transcriptional regulator
ICDKHGKO_03537 6.6e-295 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
ICDKHGKO_03538 2.3e-219 gntP EG COG2610 H gluconate symporter and related permeases
ICDKHGKO_03539 3.5e-129 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
ICDKHGKO_03540 1.7e-265 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
ICDKHGKO_03541 1.8e-133 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
ICDKHGKO_03542 2.1e-208 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ICDKHGKO_03543 1.4e-117 yvfI K COG2186 Transcriptional regulators
ICDKHGKO_03544 3.8e-296 yvfH C L-lactate permease
ICDKHGKO_03545 8.8e-232 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
ICDKHGKO_03546 2.7e-32 yvfG S YvfG protein
ICDKHGKO_03547 2.3e-176 yvfF GM Exopolysaccharide biosynthesis protein
ICDKHGKO_03548 2.7e-216 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
ICDKHGKO_03549 1.1e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
ICDKHGKO_03550 1.8e-102 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
ICDKHGKO_03551 1.5e-267 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICDKHGKO_03552 2e-186 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
ICDKHGKO_03553 2e-197 epsI GM pyruvyl transferase
ICDKHGKO_03554 4.6e-191 epsH GT2 S Glycosyltransferase like family 2
ICDKHGKO_03555 1.4e-201 epsG S EpsG family
ICDKHGKO_03556 3.8e-199 epsF GT4 M Glycosyl transferases group 1
ICDKHGKO_03557 8.6e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ICDKHGKO_03558 3.6e-213 epsD GT4 M Glycosyl transferase 4-like
ICDKHGKO_03559 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
ICDKHGKO_03560 7.1e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
ICDKHGKO_03561 3.3e-116 ywqC M biosynthesis protein
ICDKHGKO_03562 5.1e-78 slr K transcriptional
ICDKHGKO_03563 6.5e-236 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
ICDKHGKO_03565 1.3e-85 ywjB H RibD C-terminal domain
ICDKHGKO_03566 1.7e-130 CH FAD binding domain
ICDKHGKO_03567 9.3e-74 S Metallo-beta-lactamase superfamily
ICDKHGKO_03568 3e-105 yyaS S Membrane
ICDKHGKO_03569 1e-82 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ICDKHGKO_03570 1.2e-93 padC Q Phenolic acid decarboxylase
ICDKHGKO_03571 9.4e-50 MA20_18690 S Protein of unknown function (DUF3237)
ICDKHGKO_03572 6.1e-31 S Protein of unknown function (DUF1433)
ICDKHGKO_03573 5e-17 S Protein of unknown function (DUF1433)
ICDKHGKO_03574 4.8e-19 S Protein of unknown function (DUF1433)
ICDKHGKO_03575 5.8e-253 I Pfam Lipase (class 3)
ICDKHGKO_03576 7.6e-33
ICDKHGKO_03578 2.8e-279 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
ICDKHGKO_03579 7.8e-214 rafB P LacY proton/sugar symporter
ICDKHGKO_03580 4.6e-177 scrR K transcriptional
ICDKHGKO_03581 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ICDKHGKO_03582 7.2e-158 yraN K Transcriptional regulator
ICDKHGKO_03583 3.7e-202 yraM S PrpF protein
ICDKHGKO_03584 8.3e-241 EGP Sugar (and other) transporter
ICDKHGKO_03585 5.3e-89
ICDKHGKO_03586 6.4e-102 yvdD 3.2.2.10 S Belongs to the LOG family
ICDKHGKO_03587 7.1e-50 yvdC S MazG nucleotide pyrophosphohydrolase domain
ICDKHGKO_03588 6.4e-277 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
ICDKHGKO_03589 4.1e-104 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
ICDKHGKO_03590 2.9e-179 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ICDKHGKO_03591 1.3e-76 M Ribonuclease
ICDKHGKO_03592 1.5e-130 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
ICDKHGKO_03593 1.4e-35 crh G Phosphocarrier protein Chr
ICDKHGKO_03594 1.2e-169 whiA K May be required for sporulation
ICDKHGKO_03595 3.2e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
ICDKHGKO_03596 3.3e-166 rapZ S Displays ATPase and GTPase activities
ICDKHGKO_03597 8.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
ICDKHGKO_03598 5.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ICDKHGKO_03599 2.1e-117 usp CBM50 M protein conserved in bacteria
ICDKHGKO_03600 4.2e-267 S COG0457 FOG TPR repeat
ICDKHGKO_03601 6.8e-182 sasA T Histidine kinase
ICDKHGKO_03602 4.4e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICDKHGKO_03603 0.0 msbA2 3.6.3.44 V ABC transporter
ICDKHGKO_03604 2.2e-108 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
ICDKHGKO_03605 1.2e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
ICDKHGKO_03606 6.7e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ICDKHGKO_03607 1.4e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICDKHGKO_03608 8.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
ICDKHGKO_03609 1.7e-219 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ICDKHGKO_03610 1.4e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
ICDKHGKO_03611 1.8e-199 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ICDKHGKO_03612 7.2e-135 yvpB NU protein conserved in bacteria
ICDKHGKO_03613 2.4e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
ICDKHGKO_03614 1.3e-111 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
ICDKHGKO_03615 3.4e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICDKHGKO_03616 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ICDKHGKO_03617 3.4e-214 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICDKHGKO_03618 4.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ICDKHGKO_03619 7.6e-132 yvoA K transcriptional
ICDKHGKO_03620 3.2e-101 yxaF K Transcriptional regulator
ICDKHGKO_03621 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
ICDKHGKO_03622 9.1e-46 yvlD S Membrane
ICDKHGKO_03623 9.6e-26 pspB KT PspC domain
ICDKHGKO_03624 5.6e-163 yvlB S Putative adhesin
ICDKHGKO_03625 4e-46 yvlA
ICDKHGKO_03626 3.6e-30 yvkN
ICDKHGKO_03627 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ICDKHGKO_03628 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ICDKHGKO_03629 7.6e-33 csbA S protein conserved in bacteria
ICDKHGKO_03630 0.0 yvkC 2.7.9.2 GT Phosphotransferase
ICDKHGKO_03631 6.2e-126 yvkC 2.7.9.2 GT Phosphotransferase
ICDKHGKO_03632 1e-91 yvkB K Transcriptional regulator
ICDKHGKO_03633 6.5e-222 yvkA EGP Major facilitator Superfamily
ICDKHGKO_03634 4.5e-25 yuaB
ICDKHGKO_03636 1.1e-217 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICDKHGKO_03637 2.9e-54 swrA S Swarming motility protein
ICDKHGKO_03638 3.8e-249 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
ICDKHGKO_03639 6.9e-190 ywoF P Right handed beta helix region
ICDKHGKO_03640 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
ICDKHGKO_03641 2.3e-122 ftsE D cell division ATP-binding protein FtsE
ICDKHGKO_03642 5.2e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
ICDKHGKO_03643 1.5e-147 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
ICDKHGKO_03644 9.4e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ICDKHGKO_03645 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ICDKHGKO_03646 4.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ICDKHGKO_03647 6.8e-68
ICDKHGKO_03648 1.3e-09 fliT S bacterial-type flagellum organization
ICDKHGKO_03649 7e-63 fliS N flagellar protein FliS
ICDKHGKO_03650 9.5e-238 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ICDKHGKO_03651 1.9e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ICDKHGKO_03652 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICDKHGKO_03653 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ICDKHGKO_03654 8.3e-78 yviE
ICDKHGKO_03655 7.4e-161 flgL N Belongs to the bacterial flagellin family
ICDKHGKO_03656 2.2e-271 flgK N flagellar hook-associated protein
ICDKHGKO_03657 5.4e-78 flgN NOU FlgN protein
ICDKHGKO_03658 2.3e-38 flgM KNU Negative regulator of flagellin synthesis
ICDKHGKO_03659 3.9e-72 yvyF S flagellar protein
ICDKHGKO_03660 6.2e-62 comFC S Phosphoribosyl transferase domain
ICDKHGKO_03661 8.2e-42 comFB S Late competence development protein ComFB
ICDKHGKO_03662 2.9e-249 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ICDKHGKO_03663 8.1e-154 degV S protein conserved in bacteria
ICDKHGKO_03664 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICDKHGKO_03665 2.4e-180 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
ICDKHGKO_03666 1e-116 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
ICDKHGKO_03667 4.2e-170 yvhJ K Transcriptional regulator
ICDKHGKO_03668 1.4e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
ICDKHGKO_03669 5.6e-225 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
ICDKHGKO_03670 1.9e-141 tuaG GT2 M Glycosyltransferase like family 2
ICDKHGKO_03671 1.6e-107 tuaF M protein involved in exopolysaccharide biosynthesis
ICDKHGKO_03672 5.4e-251 tuaE M Teichuronic acid biosynthesis protein
ICDKHGKO_03673 1.5e-242 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ICDKHGKO_03674 1.4e-212 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
ICDKHGKO_03675 4.8e-255 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ICDKHGKO_03676 1.4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
ICDKHGKO_03677 3.3e-211 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ICDKHGKO_03678 1.1e-303 lytB 3.5.1.28 D Stage II sporulation protein
ICDKHGKO_03679 1e-29
ICDKHGKO_03680 5.2e-138 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
ICDKHGKO_03681 1.2e-184 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ICDKHGKO_03682 2.1e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ICDKHGKO_03683 1e-178 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
ICDKHGKO_03684 3.4e-136 tagG GM Transport permease protein
ICDKHGKO_03685 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ICDKHGKO_03686 1.3e-258 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
ICDKHGKO_03687 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
ICDKHGKO_03688 1.4e-139 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
ICDKHGKO_03689 7.6e-203 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ICDKHGKO_03690 1.5e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ICDKHGKO_03691 3.8e-184 pmi 5.3.1.8 G mannose-6-phosphate isomerase
ICDKHGKO_03692 3.2e-251 gerBA EG Spore germination protein
ICDKHGKO_03693 1.4e-190 gerBB E Spore germination protein
ICDKHGKO_03694 1.7e-171 gerAC S Spore germination protein
ICDKHGKO_03695 4.4e-258 GT2,GT4 J Glycosyl transferase family 2
ICDKHGKO_03696 1.6e-239 ywtG EGP Major facilitator Superfamily
ICDKHGKO_03697 1.1e-173 ywtF K Transcriptional regulator
ICDKHGKO_03698 1.4e-153 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
ICDKHGKO_03699 4.1e-29 yttA 2.7.13.3 S Pfam Transposase IS66
ICDKHGKO_03700 8.6e-229 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
ICDKHGKO_03701 5e-20 ywtC
ICDKHGKO_03702 1.2e-216 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
ICDKHGKO_03703 2.3e-70 pgsC S biosynthesis protein
ICDKHGKO_03704 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
ICDKHGKO_03705 1.2e-184 gerKA EG Spore germination protein
ICDKHGKO_03706 2.1e-178 gerKB E Spore germination protein
ICDKHGKO_03707 3.1e-50 gerKC S Spore germination B3/ GerAC like, C-terminal
ICDKHGKO_03708 4.4e-113 gerKC S Spore germination B3/ GerAC like, C-terminal
ICDKHGKO_03709 3.7e-174 rbsR K transcriptional
ICDKHGKO_03710 6.5e-154 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICDKHGKO_03711 9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ICDKHGKO_03712 8.4e-271 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
ICDKHGKO_03713 3.5e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
ICDKHGKO_03714 3.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
ICDKHGKO_03715 3.9e-85 batE T Sh3 type 3 domain protein
ICDKHGKO_03716 7.5e-89 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
ICDKHGKO_03717 9e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
ICDKHGKO_03718 9.6e-303 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
ICDKHGKO_03719 7.1e-164 alsR K LysR substrate binding domain
ICDKHGKO_03720 1.1e-232 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ICDKHGKO_03721 1.2e-115 ywrJ
ICDKHGKO_03722 1.5e-113 cotB
ICDKHGKO_03723 8.5e-204 cotH M Spore Coat
ICDKHGKO_03724 1.2e-06
ICDKHGKO_03725 6.2e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ICDKHGKO_03727 1.6e-291 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
ICDKHGKO_03728 3e-81 ywrC K Transcriptional regulator
ICDKHGKO_03729 2e-98 ywrB P Chromate transporter
ICDKHGKO_03730 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
ICDKHGKO_03731 3.3e-102
ICDKHGKO_03732 4.9e-63
ICDKHGKO_03733 1.3e-73 S SMI1 / KNR4 family
ICDKHGKO_03734 3.6e-18
ICDKHGKO_03735 8.4e-59 S SUKH-4 immunity protein
ICDKHGKO_03736 4.9e-231 ywqJ S Pre-toxin TG
ICDKHGKO_03737 1.4e-35 ywqI S Family of unknown function (DUF5344)
ICDKHGKO_03738 1.7e-17 S Domain of unknown function (DUF5082)
ICDKHGKO_03739 4.2e-144 ywqG S Domain of unknown function (DUF1963)
ICDKHGKO_03740 1e-240 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ICDKHGKO_03741 8.2e-137 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
ICDKHGKO_03742 8.5e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
ICDKHGKO_03743 1.2e-105 ywqC M biosynthesis protein
ICDKHGKO_03744 2.6e-15
ICDKHGKO_03745 2.9e-301 ywqB S SWIM zinc finger
ICDKHGKO_03746 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
ICDKHGKO_03747 7.2e-150 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
ICDKHGKO_03748 5.4e-136 glcR K DeoR C terminal sensor domain
ICDKHGKO_03749 5.4e-56 ssbB L Single-stranded DNA-binding protein
ICDKHGKO_03750 2.5e-56 ywpG
ICDKHGKO_03751 9.9e-68 ywpF S YwpF-like protein
ICDKHGKO_03752 5.9e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ICDKHGKO_03753 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ICDKHGKO_03754 1.1e-192 S aspartate phosphatase
ICDKHGKO_03755 1.5e-136 flhP N flagellar basal body
ICDKHGKO_03756 8e-127 flhO N flagellar basal body
ICDKHGKO_03757 2.7e-180 mbl D Rod shape-determining protein
ICDKHGKO_03758 1.8e-44 spoIIID K Stage III sporulation protein D
ICDKHGKO_03759 1.1e-71 ywoH K transcriptional
ICDKHGKO_03760 4.1e-212 ywoG EGP Major facilitator Superfamily
ICDKHGKO_03761 2.4e-270 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
ICDKHGKO_03762 9.8e-242 ywoD EGP Major facilitator superfamily
ICDKHGKO_03763 8.5e-99 phzA Q Isochorismatase family
ICDKHGKO_03764 3.9e-226 amt P Ammonium transporter
ICDKHGKO_03765 1.7e-57 nrgB K Belongs to the P(II) protein family
ICDKHGKO_03766 1.1e-206 ftsW D Belongs to the SEDS family
ICDKHGKO_03767 1.3e-99 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
ICDKHGKO_03768 6.4e-67 ywnJ S VanZ like family
ICDKHGKO_03769 2.7e-120 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
ICDKHGKO_03770 3.9e-87 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
ICDKHGKO_03771 3.1e-11 ywnC S Family of unknown function (DUF5362)
ICDKHGKO_03772 1.3e-67 ywnF S Family of unknown function (DUF5392)
ICDKHGKO_03773 1.2e-274 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICDKHGKO_03774 8.6e-16 yqgA
ICDKHGKO_03775 1.3e-50 ywnC S Family of unknown function (DUF5362)
ICDKHGKO_03776 3.7e-90 ywnB S NAD(P)H-binding
ICDKHGKO_03777 6.1e-67 ywnA K Transcriptional regulator
ICDKHGKO_03778 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
ICDKHGKO_03779 5.5e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
ICDKHGKO_03780 2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
ICDKHGKO_03781 5.3e-09 csbD K CsbD-like
ICDKHGKO_03782 1.2e-80 ywmF S Peptidase M50
ICDKHGKO_03783 8.2e-93 S response regulator aspartate phosphatase
ICDKHGKO_03784 3.8e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ICDKHGKO_03785 1e-142 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ICDKHGKO_03787 8.1e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
ICDKHGKO_03788 1.3e-112 ywmC S protein containing a von Willebrand factor type A (vWA) domain
ICDKHGKO_03789 1.2e-180 spoIID D Stage II sporulation protein D
ICDKHGKO_03790 8.2e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICDKHGKO_03791 1.7e-131 ywmB S TATA-box binding
ICDKHGKO_03792 6.2e-32 ywzB S membrane
ICDKHGKO_03793 4.3e-88 ywmA
ICDKHGKO_03794 5.3e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ICDKHGKO_03795 1e-265 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICDKHGKO_03796 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICDKHGKO_03797 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICDKHGKO_03798 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICDKHGKO_03799 3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICDKHGKO_03800 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICDKHGKO_03801 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
ICDKHGKO_03802 2.8e-61 atpI S ATP synthase
ICDKHGKO_03803 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ICDKHGKO_03804 9.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICDKHGKO_03805 3.2e-95 ywlG S Belongs to the UPF0340 family
ICDKHGKO_03806 4.6e-79 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
ICDKHGKO_03807 1.1e-72 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICDKHGKO_03808 6.2e-86 mntP P Probably functions as a manganese efflux pump
ICDKHGKO_03809 2.9e-185 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ICDKHGKO_03810 3.7e-73 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
ICDKHGKO_03811 2.1e-115 spoIIR S stage II sporulation protein R
ICDKHGKO_03812 9.7e-59 ywlA S Uncharacterised protein family (UPF0715)
ICDKHGKO_03814 8.5e-151 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ICDKHGKO_03815 7.5e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICDKHGKO_03816 2.4e-65 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICDKHGKO_03817 2.7e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
ICDKHGKO_03818 1.1e-151 ywkB S Membrane transport protein
ICDKHGKO_03819 0.0 sfcA 1.1.1.38 C malic enzyme
ICDKHGKO_03820 5.6e-101 tdk 2.7.1.21 F thymidine kinase
ICDKHGKO_03821 1.1e-32 rpmE J Binds the 23S rRNA
ICDKHGKO_03822 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ICDKHGKO_03823 1.1e-173 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
ICDKHGKO_03824 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICDKHGKO_03825 7.1e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ICDKHGKO_03826 2.7e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
ICDKHGKO_03827 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
ICDKHGKO_03828 1.8e-90 ywjG S Domain of unknown function (DUF2529)
ICDKHGKO_03829 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ICDKHGKO_03830 7.1e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ICDKHGKO_03831 0.0 fadF C COG0247 Fe-S oxidoreductase
ICDKHGKO_03832 1.1e-201 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
ICDKHGKO_03833 2.1e-174 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
ICDKHGKO_03834 9.3e-43 ywjC
ICDKHGKO_03835 0.0 ywjA V ABC transporter
ICDKHGKO_03836 2.7e-288 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICDKHGKO_03837 1.4e-116 narI 1.7.5.1 C nitrate reductase, gamma
ICDKHGKO_03838 4e-85 narJ 1.7.5.1 C nitrate reductase
ICDKHGKO_03839 3.8e-292 narH 1.7.5.1 C Nitrate reductase, beta
ICDKHGKO_03840 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICDKHGKO_03841 1.4e-78 arfM T cyclic nucleotide binding
ICDKHGKO_03842 1.6e-126 ywiC S YwiC-like protein
ICDKHGKO_03843 1.4e-125 fnr K helix_turn_helix, cAMP Regulatory protein
ICDKHGKO_03844 4.3e-209 narK P COG2223 Nitrate nitrite transporter
ICDKHGKO_03845 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ICDKHGKO_03846 1.5e-71 ywiB S protein conserved in bacteria
ICDKHGKO_03848 1.2e-189 ywhL CO amine dehydrogenase activity
ICDKHGKO_03849 5.8e-78 S aspartate phosphatase
ICDKHGKO_03851 2.3e-167 speB 3.5.3.11 E Belongs to the arginase family
ICDKHGKO_03852 1.6e-157 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ICDKHGKO_03853 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ICDKHGKO_03854 3e-72
ICDKHGKO_03855 5.1e-90 ywhD S YwhD family
ICDKHGKO_03856 8.1e-117 ywhC S Peptidase family M50
ICDKHGKO_03857 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
ICDKHGKO_03858 9.8e-68 ywhA K Transcriptional regulator
ICDKHGKO_03859 4.9e-241 yhdG_1 E C-terminus of AA_permease
ICDKHGKO_03860 1.7e-87 ywgA 2.1.1.72, 3.1.21.3
ICDKHGKO_03861 9e-253 ywfO S COG1078 HD superfamily phosphohydrolases
ICDKHGKO_03862 6.9e-36 ywzC S Belongs to the UPF0741 family
ICDKHGKO_03863 1.6e-103 rsfA_1
ICDKHGKO_03864 4.1e-50 padR K PadR family transcriptional regulator
ICDKHGKO_03865 4e-85 S membrane
ICDKHGKO_03866 2.2e-152 V ABC transporter, ATP-binding protein
ICDKHGKO_03867 1.1e-162 yhcI S ABC transporter (permease)
ICDKHGKO_03870 6.1e-163
ICDKHGKO_03872 2e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
ICDKHGKO_03873 1.3e-154 cysL K Transcriptional regulator
ICDKHGKO_03874 6.7e-152 MA20_14895 S Conserved hypothetical protein 698
ICDKHGKO_03875 8.1e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
ICDKHGKO_03876 4.8e-145 ywfI C May function as heme-dependent peroxidase
ICDKHGKO_03877 2.3e-14 K Helix-turn-helix XRE-family like proteins
ICDKHGKO_03879 2.6e-138 IQ Enoyl-(Acyl carrier protein) reductase
ICDKHGKO_03880 7.1e-228 ywfG 2.6.1.83 E Aminotransferase class I and II
ICDKHGKO_03881 6.1e-208 bacE EGP Major facilitator Superfamily
ICDKHGKO_03882 1e-262 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
ICDKHGKO_03883 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICDKHGKO_03884 4.9e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
ICDKHGKO_03885 1.4e-83 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
ICDKHGKO_03886 4.4e-217 ywfA EGP Major facilitator Superfamily
ICDKHGKO_03887 6e-195 tcaB EGP Major facilitator Superfamily
ICDKHGKO_03888 4.2e-256 lysP E amino acid
ICDKHGKO_03889 0.0 rocB E arginine degradation protein
ICDKHGKO_03890 2.1e-293 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
ICDKHGKO_03891 1.1e-245 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
ICDKHGKO_03892 2.6e-61
ICDKHGKO_03893 1.3e-84 spsL 5.1.3.13 M Spore Coat
ICDKHGKO_03894 5.6e-155 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ICDKHGKO_03895 1e-176 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ICDKHGKO_03896 4.5e-132 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ICDKHGKO_03897 1.4e-165 spsG M Spore Coat
ICDKHGKO_03898 2.6e-124 spsF M Spore Coat
ICDKHGKO_03899 1.4e-209 spsE 2.5.1.56 M acid synthase
ICDKHGKO_03900 6.6e-151 spsD 2.3.1.210 K Spore Coat
ICDKHGKO_03901 1e-215 spsC E Belongs to the DegT DnrJ EryC1 family
ICDKHGKO_03902 2.7e-258 spsB M Capsule polysaccharide biosynthesis protein
ICDKHGKO_03903 9.4e-141 spsA M Spore Coat
ICDKHGKO_03904 1.6e-62 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
ICDKHGKO_03905 5e-55 ywdK S small membrane protein
ICDKHGKO_03906 5.6e-226 ywdJ F Xanthine uracil
ICDKHGKO_03907 5.4e-36 ywdI S Family of unknown function (DUF5327)
ICDKHGKO_03908 5.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICDKHGKO_03909 9.2e-147 ywdF GT2,GT4 S Glycosyltransferase like family 2
ICDKHGKO_03911 1.9e-144 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ICDKHGKO_03912 1.5e-20 ywdA
ICDKHGKO_03913 5.8e-269 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
ICDKHGKO_03914 2.1e-247 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ICDKHGKO_03915 7e-150 sacT K transcriptional antiterminator
ICDKHGKO_03917 0.0 vpr O Belongs to the peptidase S8 family
ICDKHGKO_03918 4.1e-181 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ICDKHGKO_03919 2.7e-118 M1-869 K WYL domain
ICDKHGKO_03920 2e-125 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ICDKHGKO_03921 3.2e-42 S Ketosteroid isomerase-related protein
ICDKHGKO_03922 2.1e-32 S Stress responsive A/B Barrel Domain
ICDKHGKO_03923 6.8e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
ICDKHGKO_03924 1.8e-207 rodA D Belongs to the SEDS family
ICDKHGKO_03925 6.3e-68 ysnE K acetyltransferase
ICDKHGKO_03926 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
ICDKHGKO_03927 1.6e-61 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
ICDKHGKO_03928 2.3e-110 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
ICDKHGKO_03929 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ICDKHGKO_03930 1.6e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
ICDKHGKO_03931 8.4e-27 ywzA S membrane
ICDKHGKO_03932 6.4e-282 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ICDKHGKO_03933 2.1e-208 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ICDKHGKO_03934 9.6e-60 gtcA S GtrA-like protein
ICDKHGKO_03935 1.1e-96 ywcC K Bacterial regulatory proteins, tetR family
ICDKHGKO_03937 1.9e-124 H Methionine biosynthesis protein MetW
ICDKHGKO_03938 6.8e-119 S Streptomycin biosynthesis protein StrF
ICDKHGKO_03939 6.3e-108 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
ICDKHGKO_03940 1e-232 ywbN P Dyp-type peroxidase family protein
ICDKHGKO_03941 2.4e-132 ycdO P periplasmic lipoprotein involved in iron transport
ICDKHGKO_03942 3.6e-194 P COG0672 High-affinity Fe2 Pb2 permease
ICDKHGKO_03943 1.8e-108 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ICDKHGKO_03944 1.4e-126 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ICDKHGKO_03945 2.6e-150 ywbI K Transcriptional regulator
ICDKHGKO_03946 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
ICDKHGKO_03947 2.2e-109 ywbG M effector of murein hydrolase
ICDKHGKO_03948 1.5e-26 ywbE S Uncharacterized conserved protein (DUF2196)
ICDKHGKO_03949 1.8e-128 mta K transcriptional
ICDKHGKO_03950 7.1e-156 yjfC O Predicted Zn-dependent protease (DUF2268)
ICDKHGKO_03951 4.9e-221 ywbD 2.1.1.191 J Methyltransferase
ICDKHGKO_03952 2.9e-66 ywbC 4.4.1.5 E glyoxalase
ICDKHGKO_03953 1.6e-241 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICDKHGKO_03954 7.8e-252 epr 3.4.21.62 O Belongs to the peptidase S8 family
ICDKHGKO_03955 1e-159 gspA M General stress
ICDKHGKO_03957 2.9e-116 ywaC 2.7.6.5 S protein conserved in bacteria
ICDKHGKO_03958 1.9e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
ICDKHGKO_03959 4.7e-12 S D-Ala-teichoic acid biosynthesis protein
ICDKHGKO_03960 9e-289 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICDKHGKO_03961 6.5e-226 dltB M membrane protein involved in D-alanine export
ICDKHGKO_03962 5.6e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ICDKHGKO_03963 5.6e-193 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ICDKHGKO_03964 5.5e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
ICDKHGKO_03965 1.5e-247 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
ICDKHGKO_03966 6.2e-49 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
ICDKHGKO_03967 1.2e-244 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICDKHGKO_03968 7.5e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
ICDKHGKO_03969 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
ICDKHGKO_03970 5.2e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
ICDKHGKO_03971 6.4e-169 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICDKHGKO_03972 3.3e-178 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ICDKHGKO_03973 2.2e-165 cbrA3 P Periplasmic binding protein
ICDKHGKO_03974 1.2e-50 arsR K transcriptional
ICDKHGKO_03975 3.9e-224 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ICDKHGKO_03976 1.5e-43 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
ICDKHGKO_03977 1.9e-47 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
ICDKHGKO_03978 1.8e-224 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ICDKHGKO_03979 1.8e-278 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ICDKHGKO_03980 1.1e-161 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
ICDKHGKO_03981 3.1e-178 manA 5.3.1.8 G mannose-6-phosphate isomerase
ICDKHGKO_03982 6.9e-206 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
ICDKHGKO_03983 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
ICDKHGKO_03984 2e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
ICDKHGKO_03985 7e-248 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
ICDKHGKO_03986 2e-109 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICDKHGKO_03987 9e-29 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICDKHGKO_03988 4.8e-286 cydD V ATP-binding protein
ICDKHGKO_03989 6.4e-307 cydD V ATP-binding
ICDKHGKO_03990 5.7e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
ICDKHGKO_03991 3.8e-265 cydA 1.10.3.14 C oxidase, subunit
ICDKHGKO_03992 2.3e-211 cimH C COG3493 Na citrate symporter
ICDKHGKO_03993 1.2e-149 yxkH G Polysaccharide deacetylase
ICDKHGKO_03994 6.5e-204 msmK P Belongs to the ABC transporter superfamily
ICDKHGKO_03995 2e-155 lrp QT PucR C-terminal helix-turn-helix domain
ICDKHGKO_03996 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ICDKHGKO_03998 9.7e-83 yxkC S Domain of unknown function (DUF4352)
ICDKHGKO_03999 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ICDKHGKO_04000 2.6e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
ICDKHGKO_04003 3e-81 yxjI S LURP-one-related
ICDKHGKO_04004 9.4e-214 yxjG 2.1.1.14 E Methionine synthase
ICDKHGKO_04005 1.8e-143 rlmA 2.1.1.187 Q Methyltransferase domain
ICDKHGKO_04006 6.8e-208 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICDKHGKO_04007 6e-67 T Domain of unknown function (DUF4163)
ICDKHGKO_04008 2.8e-45 yxiS
ICDKHGKO_04009 6.4e-181 L DNA synthesis involved in DNA repair
ICDKHGKO_04010 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
ICDKHGKO_04011 6.8e-221 citH C Citrate transporter
ICDKHGKO_04012 3.8e-136 exoK GH16 M licheninase activity
ICDKHGKO_04013 1.8e-142 licT K transcriptional antiterminator
ICDKHGKO_04014 1.6e-219 yxiO S COG2270 Permeases of the major facilitator superfamily
ICDKHGKO_04015 3.4e-253 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
ICDKHGKO_04017 1.4e-21
ICDKHGKO_04018 5.8e-14 S YxiJ-like protein
ICDKHGKO_04019 3.9e-111
ICDKHGKO_04020 2.7e-44
ICDKHGKO_04021 1.4e-31 yxiG
ICDKHGKO_04022 2.6e-57 yxxG
ICDKHGKO_04024 5.7e-197 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
ICDKHGKO_04025 1.5e-142 yxxF EG EamA-like transporter family
ICDKHGKO_04026 4.1e-72 yxiE T Belongs to the universal stress protein A family
ICDKHGKO_04027 1.1e-275 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ICDKHGKO_04028 6.8e-307 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ICDKHGKO_04029 1.7e-46 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
ICDKHGKO_04030 2e-146 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
ICDKHGKO_04031 9.7e-163 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
ICDKHGKO_04032 2e-262 L Z1 domain
ICDKHGKO_04033 3.4e-82 S Putative PD-(D/E)XK family member, (DUF4420)
ICDKHGKO_04034 3.3e-197 S AIPR protein
ICDKHGKO_04035 2e-266 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
ICDKHGKO_04036 8.5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
ICDKHGKO_04037 1.1e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
ICDKHGKO_04038 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ICDKHGKO_04039 9.4e-231 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
ICDKHGKO_04040 1e-168 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
ICDKHGKO_04041 5e-249 lysP E amino acid
ICDKHGKO_04042 3.3e-231 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
ICDKHGKO_04043 1.2e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ICDKHGKO_04044 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICDKHGKO_04045 5.3e-170 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
ICDKHGKO_04046 2.1e-146 yidA S hydrolases of the HAD superfamily
ICDKHGKO_04051 7.9e-21 yxeD
ICDKHGKO_04052 2.7e-35
ICDKHGKO_04053 1.2e-169 fhuD P Periplasmic binding protein
ICDKHGKO_04054 2.7e-55 yxeA S Protein of unknown function (DUF1093)
ICDKHGKO_04055 0.0 yxdM V ABC transporter (permease)
ICDKHGKO_04056 1.4e-136 yxdL V ABC transporter, ATP-binding protein
ICDKHGKO_04057 9.6e-175 T PhoQ Sensor
ICDKHGKO_04058 3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICDKHGKO_04059 4.6e-152 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
ICDKHGKO_04060 1.4e-145 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
ICDKHGKO_04061 6.8e-164 iolH G Xylose isomerase-like TIM barrel
ICDKHGKO_04062 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
ICDKHGKO_04063 1e-227 iolF EGP Major facilitator Superfamily
ICDKHGKO_04064 1.8e-172 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
ICDKHGKO_04065 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
ICDKHGKO_04066 1.6e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
ICDKHGKO_04067 8.7e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
ICDKHGKO_04068 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ICDKHGKO_04069 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
ICDKHGKO_04070 4.4e-169 iolS C Aldo keto reductase
ICDKHGKO_04071 4.8e-244 csbC EGP Major facilitator Superfamily
ICDKHGKO_04072 0.0 htpG O Molecular chaperone. Has ATPase activity
ICDKHGKO_04073 2.5e-147 IQ Enoyl-(Acyl carrier protein) reductase
ICDKHGKO_04074 1.6e-100 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ICDKHGKO_04075 3.5e-192 desK 2.7.13.3 T Histidine kinase
ICDKHGKO_04076 1.2e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
ICDKHGKO_04077 1.4e-209 yxbF K Bacterial regulatory proteins, tetR family
ICDKHGKO_04078 4.9e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
ICDKHGKO_04079 3.2e-138 S PQQ-like domain
ICDKHGKO_04080 2.7e-57 S Family of unknown function (DUF5391)
ICDKHGKO_04081 4.3e-49 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
ICDKHGKO_04082 1.1e-198 EGP Major facilitator Superfamily
ICDKHGKO_04083 2.2e-65 yxaI S membrane protein domain
ICDKHGKO_04084 4.5e-118 E Ring-cleavage extradiol dioxygenase
ICDKHGKO_04085 9.4e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
ICDKHGKO_04086 8.9e-284 ahpF O Alkyl hydroperoxide reductase
ICDKHGKO_04087 9e-186 G Major royal jelly protein
ICDKHGKO_04088 1e-235 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
ICDKHGKO_04089 3.4e-156 K helix_turn_helix, Deoxyribose operon repressor
ICDKHGKO_04090 1.4e-73 K Integron-associated effector binding protein
ICDKHGKO_04091 5.4e-75 yjhE S Phage tail protein
ICDKHGKO_04092 0.0 L Transposase and inactivated derivatives, TnpA family
ICDKHGKO_04093 7.1e-85 L resolvase
ICDKHGKO_04094 1.3e-78
ICDKHGKO_04096 6e-26 S Protein of unknown function (DUF1657)
ICDKHGKO_04097 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ICDKHGKO_04098 2.6e-80 spoVAC S stage V sporulation protein AC
ICDKHGKO_04099 1e-195 spoVAD I Stage V sporulation protein AD
ICDKHGKO_04100 8.5e-57 spoVAE S stage V sporulation protein
ICDKHGKO_04101 5.8e-29 S Protein of unknown function (DUF1657)
ICDKHGKO_04102 4.7e-149 yetF1 S membrane
ICDKHGKO_04103 1.2e-70 S Protein of unknown function (DUF421)
ICDKHGKO_04104 2.7e-285 clsA_1 I PLD-like domain
ICDKHGKO_04105 2.5e-92 S Protein of unknown function (DUF421)
ICDKHGKO_04106 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
ICDKHGKO_04107 3.2e-78 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
ICDKHGKO_04108 4.9e-143 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
ICDKHGKO_04109 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
ICDKHGKO_04110 1.6e-82 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
ICDKHGKO_04111 5.2e-157 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ICDKHGKO_04112 4e-155 S Fusaric acid resistance protein-like
ICDKHGKO_04113 6.5e-19
ICDKHGKO_04114 2.8e-290 3.6.4.12 L AAA domain
ICDKHGKO_04115 0.0 L AAA ATPase domain
ICDKHGKO_04116 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ICDKHGKO_04117 7.9e-08 S YyzF-like protein
ICDKHGKO_04120 2.3e-207 yycP
ICDKHGKO_04121 1.9e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ICDKHGKO_04122 9.3e-178 C oxidoreductases (related to aryl-alcohol dehydrogenases)
ICDKHGKO_04123 1.4e-81 yycN 2.3.1.128 K Acetyltransferase
ICDKHGKO_04125 2.1e-197 S Histidine kinase
ICDKHGKO_04126 8.2e-165 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
ICDKHGKO_04127 1.5e-253 rocE E amino acid
ICDKHGKO_04128 8.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
ICDKHGKO_04129 1.6e-61 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
ICDKHGKO_04130 1.3e-42 sdpR K transcriptional
ICDKHGKO_04131 4.7e-253 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
ICDKHGKO_04132 8.4e-197 S Major Facilitator Superfamily
ICDKHGKO_04133 3.7e-244 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
ICDKHGKO_04134 6.5e-93 K PFAM response regulator receiver
ICDKHGKO_04135 1.4e-45 S Peptidase propeptide and YPEB domain
ICDKHGKO_04136 3.4e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICDKHGKO_04137 6.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
ICDKHGKO_04138 3.3e-147 yycI S protein conserved in bacteria
ICDKHGKO_04139 8.2e-257 yycH S protein conserved in bacteria
ICDKHGKO_04140 0.0 vicK 2.7.13.3 T Histidine kinase
ICDKHGKO_04141 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ICDKHGKO_04146 3.9e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ICDKHGKO_04147 2.5e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICDKHGKO_04148 6.1e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ICDKHGKO_04149 2.2e-25 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
ICDKHGKO_04151 2.3e-16 yycC K YycC-like protein
ICDKHGKO_04152 2.1e-214 M Glycosyltransferase Family 4
ICDKHGKO_04153 6.1e-191 S Ecdysteroid kinase
ICDKHGKO_04154 5.2e-231 S Carbamoyl-phosphate synthase L chain, ATP binding domain
ICDKHGKO_04155 6e-220 M Glycosyltransferase Family 4
ICDKHGKO_04156 1.8e-116 S GlcNAc-PI de-N-acetylase
ICDKHGKO_04157 1.9e-80 KLT COG0515 Serine threonine protein kinase
ICDKHGKO_04158 8.3e-73 rplI J binds to the 23S rRNA
ICDKHGKO_04159 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
ICDKHGKO_04160 2.5e-148 yybS S membrane
ICDKHGKO_04161 4.9e-79 cotF M Spore coat protein
ICDKHGKO_04162 1.2e-64 ydeP3 K Transcriptional regulator
ICDKHGKO_04163 7.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
ICDKHGKO_04164 2.5e-150 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ICDKHGKO_04165 2e-266 sacB 2.4.1.10 GH68 M levansucrase activity
ICDKHGKO_04166 1.2e-301 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
ICDKHGKO_04167 1.1e-108 K FCD domain
ICDKHGKO_04168 1.9e-73 dinB S PFAM DinB family protein
ICDKHGKO_04169 1.1e-146 G Major Facilitator Superfamily
ICDKHGKO_04170 4.2e-54 ypaA S Protein of unknown function (DUF1304)
ICDKHGKO_04171 4.4e-112 drgA C nitroreductase
ICDKHGKO_04172 1.6e-65 ydgJ K Winged helix DNA-binding domain
ICDKHGKO_04173 5.3e-148 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
ICDKHGKO_04174 3.1e-75 yybA 2.3.1.57 K transcriptional
ICDKHGKO_04175 1.8e-70 yjcF S Acetyltransferase (GNAT) domain
ICDKHGKO_04176 3.3e-19 cadC3 K transcriptional
ICDKHGKO_04177 1.1e-102 S Alpha/beta hydrolase family
ICDKHGKO_04178 3.4e-54 L Recombinase
ICDKHGKO_04179 3e-117 S response regulator aspartate phosphatase
ICDKHGKO_04180 2.9e-13 S Domain of unknown function (DUF4367)
ICDKHGKO_04182 2e-43 S Domain of unknown function with cystatin-like fold (DUF4467)
ICDKHGKO_04183 1.4e-55 yddI
ICDKHGKO_04184 8.5e-158 yddH CBM50 M Lysozyme-like
ICDKHGKO_04185 2.6e-205 yddG S maturation of SSU-rRNA
ICDKHGKO_04186 1.8e-34 S Domain of unknown function (DUF1874)
ICDKHGKO_04187 0.0 yddE S AAA-like domain
ICDKHGKO_04188 2.3e-74 yddD S TcpE family
ICDKHGKO_04189 8e-25 yddC
ICDKHGKO_04190 7.6e-125 yddB S Conjugative transposon protein TcpC
ICDKHGKO_04195 8.4e-16 S Domain of Unknown Function with PDB structure (DUF3850)
ICDKHGKO_04196 6.5e-169 nicK L Replication initiation factor
ICDKHGKO_04197 1.1e-123 ydcQ D Ftsk spoiiie family protein
ICDKHGKO_04198 4.1e-216 ydcQ D Ftsk spoiiie family protein
ICDKHGKO_04200 1.8e-33 S Bacterial protein of unknown function (DUF961)
ICDKHGKO_04202 3.5e-14
ICDKHGKO_04203 1.9e-41 yvaO K Transcriptional
ICDKHGKO_04204 5.6e-44 immA E IrrE N-terminal-like domain
ICDKHGKO_04206 3.9e-66 S response regulator aspartate phosphatase
ICDKHGKO_04207 5.4e-22 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
ICDKHGKO_04208 3.5e-129 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
ICDKHGKO_04209 1.6e-213 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
ICDKHGKO_04210 1.3e-149 yyaK S CAAX protease self-immunity
ICDKHGKO_04211 3.5e-236 ydjK G Sugar (and other) transporter
ICDKHGKO_04212 5.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ICDKHGKO_04213 8.8e-93 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
ICDKHGKO_04214 1.4e-60 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
ICDKHGKO_04215 1.7e-139 xth 3.1.11.2 L exodeoxyribonuclease III
ICDKHGKO_04216 4.5e-86 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICDKHGKO_04217 1.2e-95 adaA 3.2.2.21 K Transcriptional regulator
ICDKHGKO_04218 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICDKHGKO_04219 8.4e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ICDKHGKO_04220 3.6e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
ICDKHGKO_04221 1.3e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ICDKHGKO_04222 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICDKHGKO_04223 2.3e-33 yyzM S protein conserved in bacteria
ICDKHGKO_04224 2.4e-168 yyaD S Membrane
ICDKHGKO_04225 4.5e-57 4.2.1.103 K FR47-like protein
ICDKHGKO_04226 1.1e-107 yyaC S Sporulation protein YyaC
ICDKHGKO_04227 4.3e-147 spo0J K Belongs to the ParB family
ICDKHGKO_04228 2.7e-135 soj D COG1192 ATPases involved in chromosome partitioning
ICDKHGKO_04229 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
ICDKHGKO_04230 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
ICDKHGKO_04231 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ICDKHGKO_04232 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ICDKHGKO_04233 8.2e-106 jag S single-stranded nucleic acid binding R3H
ICDKHGKO_04234 4.3e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ICDKHGKO_04235 1.2e-50 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ICDKHGKO_04236 5.6e-61 yosT L Bacterial transcription activator, effector binding domain
ICDKHGKO_04238 1.1e-98 yiiD K acetyltransferase
ICDKHGKO_04239 7.1e-22 yiiD K acetyltransferase
ICDKHGKO_04240 2e-164 cgeD M maturation of the outermost layer of the spore
ICDKHGKO_04241 1.4e-36 cgeC
ICDKHGKO_04242 7.8e-08 cgeA
ICDKHGKO_04243 4.3e-15 cgeA
ICDKHGKO_04244 7.7e-169 cgeB S Spore maturation protein
ICDKHGKO_04245 4.1e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
ICDKHGKO_04246 1.8e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
ICDKHGKO_04247 6.4e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ICDKHGKO_04248 4.3e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICDKHGKO_04249 2.9e-16 ypoP K transcriptional
ICDKHGKO_04250 1.7e-94 ypmS S protein conserved in bacteria
ICDKHGKO_04251 9.5e-130 ypmR E GDSL-like Lipase/Acylhydrolase
ICDKHGKO_04252 2e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
ICDKHGKO_04253 7.5e-39 ypmP S Protein of unknown function (DUF2535)
ICDKHGKO_04254 1.7e-108 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICDKHGKO_04255 1.4e-25 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICDKHGKO_04256 2.1e-59 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICDKHGKO_04257 8.7e-133 pspF K Transcriptional regulator
ICDKHGKO_04258 8.7e-61 hlyIII S protein, Hemolysin III
ICDKHGKO_04259 9.3e-36 hlyIII S protein, Hemolysin III
ICDKHGKO_04260 1.6e-31 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
ICDKHGKO_04261 4e-27 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ICDKHGKO_04262 1.7e-28 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICDKHGKO_04263 7.3e-18 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ICDKHGKO_04264 1.3e-105 ypjP S YpjP-like protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)