ORF_ID e_value Gene_name EC_number CAZy COGs Description
COKMIKJD_00001 1.7e-57
COKMIKJD_00002 1.2e-152 pstS P Phosphate
COKMIKJD_00003 1e-168 pstC P probably responsible for the translocation of the substrate across the membrane
COKMIKJD_00004 4.7e-144 pstA P Phosphate transport system permease protein PstA
COKMIKJD_00005 1.6e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COKMIKJD_00006 1.4e-203 potD P ABC transporter
COKMIKJD_00007 6.8e-134 potC P ABC transporter permease
COKMIKJD_00008 3.8e-148 potB P ABC transporter permease
COKMIKJD_00009 2.6e-208 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COKMIKJD_00010 4.2e-182 L Transposase
COKMIKJD_00011 3.6e-47 S Acetyltransferase (GNAT) domain
COKMIKJD_00012 3.4e-60 S Protein of unknown function (DUF2992)
COKMIKJD_00013 1.8e-186 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
COKMIKJD_00014 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COKMIKJD_00015 1.2e-32 ykzG S Belongs to the UPF0356 family
COKMIKJD_00016 4.4e-67
COKMIKJD_00017 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COKMIKJD_00018 7e-214 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
COKMIKJD_00019 2.8e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
COKMIKJD_00020 9.2e-205 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COKMIKJD_00021 2e-269 lpdA 1.8.1.4 C Dehydrogenase
COKMIKJD_00022 1e-162 1.1.1.27 C L-malate dehydrogenase activity
COKMIKJD_00023 3e-44 yktA S Belongs to the UPF0223 family
COKMIKJD_00024 6.7e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
COKMIKJD_00025 0.0 typA T GTP-binding protein TypA
COKMIKJD_00026 1.6e-208 ftsW D Belongs to the SEDS family
COKMIKJD_00027 4.4e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
COKMIKJD_00028 2.5e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
COKMIKJD_00029 1.8e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COKMIKJD_00030 2.8e-196 ylbL T Belongs to the peptidase S16 family
COKMIKJD_00031 1.1e-119 comEA L Competence protein ComEA
COKMIKJD_00032 8.8e-89 comEB 3.5.4.12 F ComE operon protein 2
COKMIKJD_00033 0.0 comEC S Competence protein ComEC
COKMIKJD_00034 7e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
COKMIKJD_00035 2.1e-33 rpsT J Binds directly to 16S ribosomal RNA
COKMIKJD_00036 1.3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COKMIKJD_00037 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COKMIKJD_00038 2e-166 S Tetratricopeptide repeat
COKMIKJD_00039 1.9e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COKMIKJD_00040 2.2e-222 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COKMIKJD_00041 3.2e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COKMIKJD_00042 6.6e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
COKMIKJD_00043 3.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
COKMIKJD_00044 1.1e-15
COKMIKJD_00045 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COKMIKJD_00046 3.3e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COKMIKJD_00047 1.8e-104
COKMIKJD_00048 6.5e-28
COKMIKJD_00049 1.4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COKMIKJD_00050 2.6e-54 yrvD S Pfam:DUF1049
COKMIKJD_00051 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
COKMIKJD_00052 3.2e-92 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COKMIKJD_00053 3.3e-77 T Universal stress protein family
COKMIKJD_00055 6.3e-72
COKMIKJD_00056 1e-159 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
COKMIKJD_00057 9.3e-68 S MTH538 TIR-like domain (DUF1863)
COKMIKJD_00061 4.6e-82 ndk 2.7.4.6 F Belongs to the NDK family
COKMIKJD_00062 1.7e-24 KT PspC domain
COKMIKJD_00063 5.3e-124 G phosphoglycerate mutase
COKMIKJD_00064 4.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
COKMIKJD_00065 4.3e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
COKMIKJD_00066 2.1e-79
COKMIKJD_00067 2.1e-76 F nucleoside 2-deoxyribosyltransferase
COKMIKJD_00068 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COKMIKJD_00069 1.8e-37 ynzC S UPF0291 protein
COKMIKJD_00070 1.6e-32 yneF S Uncharacterised protein family (UPF0154)
COKMIKJD_00071 2.9e-286 mdlA V ABC transporter
COKMIKJD_00072 0.0 mdlB V ABC transporter
COKMIKJD_00073 4.5e-120 plsC 2.3.1.51 I Acyltransferase
COKMIKJD_00074 6.1e-137 yabB 2.1.1.223 L Methyltransferase small domain
COKMIKJD_00075 6.4e-44 yazA L GIY-YIG catalytic domain protein
COKMIKJD_00076 4.9e-182 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COKMIKJD_00077 7.2e-135 S Haloacid dehalogenase-like hydrolase
COKMIKJD_00078 3.8e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
COKMIKJD_00079 1.9e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COKMIKJD_00080 1.7e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COKMIKJD_00081 6.9e-85 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COKMIKJD_00082 2.1e-73
COKMIKJD_00083 4.8e-148 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COKMIKJD_00084 4.5e-138 cdsA 2.7.7.41 I Belongs to the CDS family
COKMIKJD_00085 7.8e-233 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
COKMIKJD_00086 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COKMIKJD_00087 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COKMIKJD_00088 1.4e-38
COKMIKJD_00089 1.8e-81 rimP J Required for maturation of 30S ribosomal subunits
COKMIKJD_00090 2e-190 nusA K Participates in both transcription termination and antitermination
COKMIKJD_00091 2.3e-47 ylxR K Protein of unknown function (DUF448)
COKMIKJD_00092 1.4e-44 ylxQ J ribosomal protein
COKMIKJD_00093 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COKMIKJD_00094 9.4e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COKMIKJD_00095 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COKMIKJD_00096 9.6e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COKMIKJD_00097 7.8e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COKMIKJD_00098 5.2e-83 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COKMIKJD_00099 0.0 dnaK O Heat shock 70 kDa protein
COKMIKJD_00100 4.9e-178 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COKMIKJD_00101 6.3e-17 dltX S D-Ala-teichoic acid biosynthesis protein
COKMIKJD_00102 1.7e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COKMIKJD_00103 3.8e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
COKMIKJD_00104 5.2e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COKMIKJD_00105 3.2e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COKMIKJD_00106 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COKMIKJD_00107 1.6e-27
COKMIKJD_00108 2.3e-24
COKMIKJD_00110 1.8e-62
COKMIKJD_00111 9.1e-28 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COKMIKJD_00112 1.2e-54
COKMIKJD_00113 9.7e-180 prmA J Ribosomal protein L11 methyltransferase
COKMIKJD_00114 1.6e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COKMIKJD_00115 2.1e-57
COKMIKJD_00116 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COKMIKJD_00117 8.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COKMIKJD_00118 7.4e-115 3.1.3.18 S HAD-hyrolase-like
COKMIKJD_00119 1e-164 yniA G Fructosamine kinase
COKMIKJD_00120 1.2e-157 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
COKMIKJD_00121 9.8e-97
COKMIKJD_00122 2.5e-247 hisS 6.1.1.21 J histidyl-tRNA synthetase
COKMIKJD_00123 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COKMIKJD_00124 8.2e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COKMIKJD_00125 1.9e-161 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COKMIKJD_00126 3.2e-188 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COKMIKJD_00127 8e-151 tagG U Transport permease protein
COKMIKJD_00128 3e-242 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
COKMIKJD_00129 1.9e-172 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
COKMIKJD_00130 4.8e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
COKMIKJD_00131 1.3e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
COKMIKJD_00132 5.7e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
COKMIKJD_00133 3.4e-67 hxlR K Transcriptional regulator, HxlR family
COKMIKJD_00134 7e-72 yqeY S YqeY-like protein
COKMIKJD_00135 5.3e-181 phoH T phosphate starvation-inducible protein PhoH
COKMIKJD_00136 8.5e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COKMIKJD_00137 3.4e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
COKMIKJD_00138 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COKMIKJD_00139 2.5e-149 recO L Involved in DNA repair and RecF pathway recombination
COKMIKJD_00140 3.3e-177 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
COKMIKJD_00141 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
COKMIKJD_00142 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COKMIKJD_00143 2.3e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COKMIKJD_00144 3.6e-88 K Transcriptional regulator
COKMIKJD_00145 0.0 ydgH S MMPL family
COKMIKJD_00146 6.6e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
COKMIKJD_00147 8.6e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COKMIKJD_00148 2.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COKMIKJD_00149 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COKMIKJD_00150 0.0 dnaE 2.7.7.7 L DNA polymerase
COKMIKJD_00151 1.3e-123 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
COKMIKJD_00152 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
COKMIKJD_00153 1.8e-167 cvfB S S1 domain
COKMIKJD_00154 4.6e-163 xerD D recombinase XerD
COKMIKJD_00155 3.1e-71 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COKMIKJD_00156 2.1e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COKMIKJD_00157 3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COKMIKJD_00158 2.7e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COKMIKJD_00159 1.6e-92 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COKMIKJD_00160 3.3e-181 ypbB 5.1.3.1 S Helix-turn-helix domain
COKMIKJD_00161 5e-249 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
COKMIKJD_00162 1.2e-24 M Lysin motif
COKMIKJD_00163 6.4e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
COKMIKJD_00164 1.1e-210 rpsA 1.17.7.4 J Ribosomal protein S1
COKMIKJD_00165 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
COKMIKJD_00166 1.5e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COKMIKJD_00167 2.5e-231 S Tetratricopeptide repeat protein
COKMIKJD_00168 2.1e-171 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COKMIKJD_00169 6.4e-221 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COKMIKJD_00170 0.0 yfmR S ABC transporter, ATP-binding protein
COKMIKJD_00171 2.4e-186 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COKMIKJD_00172 9.1e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COKMIKJD_00173 2.8e-114 hlyIII S protein, hemolysin III
COKMIKJD_00174 5.7e-147 DegV S EDD domain protein, DegV family
COKMIKJD_00175 3.7e-160 ypmR E GDSL-like Lipase/Acylhydrolase
COKMIKJD_00176 2.7e-103 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
COKMIKJD_00177 2.9e-34 yozE S Belongs to the UPF0346 family
COKMIKJD_00178 4.3e-73
COKMIKJD_00179 2.2e-34
COKMIKJD_00180 4.4e-40 L Transposase
COKMIKJD_00181 6.8e-72 L Transposase
COKMIKJD_00184 1.8e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COKMIKJD_00185 7.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COKMIKJD_00186 2.8e-165 dprA LU DNA protecting protein DprA
COKMIKJD_00187 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COKMIKJD_00188 1.1e-175 xerC D Belongs to the 'phage' integrase family. XerC subfamily
COKMIKJD_00189 1.8e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
COKMIKJD_00190 9.9e-261 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
COKMIKJD_00191 1e-167 lacX 5.1.3.3 G Aldose 1-epimerase
COKMIKJD_00192 3.2e-99 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COKMIKJD_00193 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COKMIKJD_00194 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COKMIKJD_00195 4.7e-182 K Transcriptional regulator
COKMIKJD_00196 4.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
COKMIKJD_00197 6.9e-96 zmp1 O PFAM peptidase M10A and M12B, matrixin and adamalysin
COKMIKJD_00198 1.3e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
COKMIKJD_00199 1.5e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COKMIKJD_00200 3.7e-65 3.6.1.55 F NUDIX domain
COKMIKJD_00201 3.6e-199 xerS L Belongs to the 'phage' integrase family
COKMIKJD_00202 1.3e-64 K Bacterial regulatory proteins, tetR family
COKMIKJD_00203 2.3e-77 S membrane
COKMIKJD_00204 7.9e-101 S membrane
COKMIKJD_00205 1.7e-42 I sulfurtransferase activity
COKMIKJD_00206 4.4e-119 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COKMIKJD_00207 1.4e-140 K Bacterial regulatory helix-turn-helix protein, lysR family
COKMIKJD_00208 6.6e-107 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COKMIKJD_00209 2.6e-49 maa S transferase hexapeptide repeat
COKMIKJD_00210 5.6e-89 K Transcriptional regulator
COKMIKJD_00211 4.2e-122 yneE K Transcriptional regulator
COKMIKJD_00212 2.1e-119 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COKMIKJD_00213 7.6e-121 Q Methyltransferase domain
COKMIKJD_00214 5.8e-125 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
COKMIKJD_00215 2.2e-16
COKMIKJD_00217 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COKMIKJD_00218 2e-91 V VanZ like family
COKMIKJD_00219 4.5e-83 ysaA V VanZ like family
COKMIKJD_00220 8.7e-75 gtcA S Teichoic acid glycosylation protein
COKMIKJD_00221 2.7e-86 folT S ECF transporter, substrate-specific component
COKMIKJD_00222 7.8e-160 degV S EDD domain protein, DegV family
COKMIKJD_00223 1.6e-230 yxiO S Vacuole effluxer Atg22 like
COKMIKJD_00224 1.1e-194 npp S type I phosphodiesterase nucleotide pyrophosphatase
COKMIKJD_00225 6.3e-70 K Transcriptional regulator
COKMIKJD_00226 0.0 FbpA K Fibronectin-binding protein
COKMIKJD_00227 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COKMIKJD_00228 1.5e-205 carA 6.3.5.5 F Belongs to the CarA family
COKMIKJD_00229 6.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COKMIKJD_00230 5.5e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COKMIKJD_00231 5.7e-81 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COKMIKJD_00232 2.8e-307 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
COKMIKJD_00233 2.4e-56 esbA S Family of unknown function (DUF5322)
COKMIKJD_00234 6.8e-66 rnhA 3.1.26.4 L Ribonuclease HI
COKMIKJD_00235 6.4e-207 yurR 1.4.5.1 E FAD dependent oxidoreductase
COKMIKJD_00236 6.1e-111 XK27_02070 S Nitroreductase family
COKMIKJD_00237 4.2e-84 K Bacterial regulatory proteins, tetR family
COKMIKJD_00238 5.3e-124 S CAAX protease self-immunity
COKMIKJD_00239 2e-53
COKMIKJD_00240 9.7e-84 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
COKMIKJD_00241 4.8e-28
COKMIKJD_00242 3.5e-244 amtB P ammonium transporter
COKMIKJD_00243 7.6e-67 FG Scavenger mRNA decapping enzyme C-term binding
COKMIKJD_00244 2.3e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
COKMIKJD_00246 8.4e-28 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COKMIKJD_00247 1.6e-105 ypsA S Belongs to the UPF0398 family
COKMIKJD_00248 3.6e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COKMIKJD_00249 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
COKMIKJD_00250 1.7e-60 P Rhodanese Homology Domain
COKMIKJD_00251 3.9e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
COKMIKJD_00252 2.7e-123 dnaD L Replication initiation and membrane attachment
COKMIKJD_00253 2.2e-210 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
COKMIKJD_00254 2.6e-83 ypmB S Protein conserved in bacteria
COKMIKJD_00255 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
COKMIKJD_00256 2e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
COKMIKJD_00257 3.7e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
COKMIKJD_00258 2.4e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
COKMIKJD_00259 1.9e-189 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COKMIKJD_00260 4.6e-268 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
COKMIKJD_00261 8.6e-153 yitU 3.1.3.104 S hydrolase
COKMIKJD_00262 8.7e-215 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COKMIKJD_00263 4.7e-79
COKMIKJD_00264 1.2e-165 S Oxidoreductase, aldo keto reductase family protein
COKMIKJD_00265 3.8e-162 akr5f 1.1.1.346 S reductase
COKMIKJD_00266 8.3e-77 K Transcriptional regulator
COKMIKJD_00267 1e-198 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
COKMIKJD_00269 3.8e-32 P ATPases associated with a variety of cellular activities
COKMIKJD_00270 4.2e-72 K helix_turn_helix, mercury resistance
COKMIKJD_00271 4.6e-74 1.1.1.219 GM Male sterility protein
COKMIKJD_00272 1.3e-179 C Zinc-binding dehydrogenase
COKMIKJD_00273 3.3e-48 S Alpha/beta hydrolase family
COKMIKJD_00274 0.0 kup P Transport of potassium into the cell
COKMIKJD_00275 2.5e-190 yjcE P Sodium proton antiporter
COKMIKJD_00276 8.6e-57 yqkB S Belongs to the HesB IscA family
COKMIKJD_00277 1.8e-177 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
COKMIKJD_00278 1.2e-114 K Bacterial regulatory proteins, tetR family
COKMIKJD_00279 3.3e-177 ybhR V ABC transporter
COKMIKJD_00280 1.3e-123 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
COKMIKJD_00281 5.2e-19 S Mor transcription activator family
COKMIKJD_00282 2.2e-18 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
COKMIKJD_00283 2.9e-41 S Mor transcription activator family
COKMIKJD_00284 6.4e-38 S Mor transcription activator family
COKMIKJD_00285 2.7e-67 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COKMIKJD_00286 7.2e-101 bm3R1 K Psort location Cytoplasmic, score
COKMIKJD_00287 0.0 yhcA V ABC transporter, ATP-binding protein
COKMIKJD_00288 1.6e-163 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COKMIKJD_00289 3e-29 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COKMIKJD_00290 1.6e-60 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
COKMIKJD_00291 2.1e-212 ica2 GT2 M Glycosyl transferase family group 2
COKMIKJD_00292 3.4e-98
COKMIKJD_00293 3.4e-114
COKMIKJD_00294 1.8e-72
COKMIKJD_00295 3.7e-28 yozG K Transcriptional regulator
COKMIKJD_00296 2.2e-46 S Protein of unknown function (DUF2975)
COKMIKJD_00297 2.2e-295 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COKMIKJD_00298 1.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
COKMIKJD_00299 4.7e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COKMIKJD_00300 1.1e-272 pipD E Dipeptidase
COKMIKJD_00301 2.5e-278 yjeM E Amino Acid
COKMIKJD_00302 1.3e-52 S Alpha/beta hydrolase of unknown function (DUF915)
COKMIKJD_00303 3.3e-136 K Helix-turn-helix
COKMIKJD_00304 2.8e-36 K Bacterial regulatory proteins, tetR family
COKMIKJD_00305 2.1e-65 npr 1.11.1.1 S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
COKMIKJD_00306 1.1e-66
COKMIKJD_00307 7.4e-100 rimL J Acetyltransferase (GNAT) domain
COKMIKJD_00308 2.2e-292 katA 1.11.1.6 C Belongs to the catalase family
COKMIKJD_00309 6e-180 C Aldo/keto reductase family
COKMIKJD_00310 1.7e-25 adhR K MerR, DNA binding
COKMIKJD_00311 5.6e-145 K LysR substrate binding domain
COKMIKJD_00312 1.1e-184 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
COKMIKJD_00313 9.6e-32 yyaQ S YjbR
COKMIKJD_00314 9.5e-93 ydeA 3.5.1.124 S DJ-1/PfpI family
COKMIKJD_00315 1.8e-45 N PFAM Uncharacterised protein family UPF0150
COKMIKJD_00316 1.2e-71 K LytTr DNA-binding domain
COKMIKJD_00317 3.5e-74 S Protein of unknown function (DUF3021)
COKMIKJD_00318 6.6e-27 entB 3.5.1.19 Q Isochorismatase family
COKMIKJD_00319 1.5e-43 entB 3.5.1.19 Q Isochorismatase family
COKMIKJD_00320 1.5e-27 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
COKMIKJD_00321 2.2e-141 yceJ EGP Major facilitator Superfamily
COKMIKJD_00322 9.9e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
COKMIKJD_00323 9.3e-84 bioY S BioY family
COKMIKJD_00324 2e-138 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COKMIKJD_00325 1.3e-126 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
COKMIKJD_00326 1.6e-140 accA 2.1.3.15, 6.4.1.2 I alpha subunit
COKMIKJD_00327 4.2e-155 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COKMIKJD_00328 1.2e-266 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
COKMIKJD_00329 5.5e-71 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
COKMIKJD_00330 6.7e-72 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COKMIKJD_00331 1.5e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COKMIKJD_00332 3.2e-122 IQ reductase
COKMIKJD_00333 1.8e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
COKMIKJD_00334 1.9e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COKMIKJD_00335 3.1e-181 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COKMIKJD_00336 2.1e-79 marR K Transcriptional regulator
COKMIKJD_00337 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COKMIKJD_00338 2.7e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COKMIKJD_00339 4.5e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COKMIKJD_00340 4.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COKMIKJD_00341 1.9e-40 ylqC S Belongs to the UPF0109 family
COKMIKJD_00342 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COKMIKJD_00343 6.1e-48
COKMIKJD_00344 2.4e-229 S Putative metallopeptidase domain
COKMIKJD_00345 6.9e-212 3.1.3.1 S associated with various cellular activities
COKMIKJD_00346 0.0 pacL 3.6.3.8 P P-type ATPase
COKMIKJD_00347 3.8e-212 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COKMIKJD_00348 2.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COKMIKJD_00349 1.4e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COKMIKJD_00350 0.0 smc D Required for chromosome condensation and partitioning
COKMIKJD_00351 2.8e-128 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COKMIKJD_00352 6.4e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COKMIKJD_00353 6.8e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COKMIKJD_00354 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COKMIKJD_00355 0.0 yloV S DAK2 domain fusion protein YloV
COKMIKJD_00356 5.2e-57 asp S Asp23 family, cell envelope-related function
COKMIKJD_00357 8.3e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
COKMIKJD_00358 1.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
COKMIKJD_00359 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
COKMIKJD_00360 1.2e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COKMIKJD_00361 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
COKMIKJD_00362 1.4e-128 stp 3.1.3.16 T phosphatase
COKMIKJD_00363 1.3e-225 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COKMIKJD_00364 1.4e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COKMIKJD_00365 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COKMIKJD_00366 2e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COKMIKJD_00367 4.9e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COKMIKJD_00368 3.3e-104 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
COKMIKJD_00369 2.2e-51
COKMIKJD_00371 2e-65 M domain protein
COKMIKJD_00372 9.7e-308 recN L May be involved in recombinational repair of damaged DNA
COKMIKJD_00373 3.7e-76 argR K Regulates arginine biosynthesis genes
COKMIKJD_00374 2.6e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
COKMIKJD_00375 1.2e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COKMIKJD_00376 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COKMIKJD_00377 1.2e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COKMIKJD_00378 1.8e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COKMIKJD_00379 7.2e-74 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COKMIKJD_00380 1.8e-72 yqhY S Asp23 family, cell envelope-related function
COKMIKJD_00381 1.3e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COKMIKJD_00382 2e-189 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COKMIKJD_00383 1.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
COKMIKJD_00384 2.2e-57 ysxB J Cysteine protease Prp
COKMIKJD_00385 3.4e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
COKMIKJD_00386 5e-93 K Transcriptional regulator
COKMIKJD_00387 1.4e-95 dut S Protein conserved in bacteria
COKMIKJD_00388 1.8e-178
COKMIKJD_00389 8.1e-157
COKMIKJD_00390 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
COKMIKJD_00391 2.1e-64 glnR K Transcriptional regulator
COKMIKJD_00392 1e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COKMIKJD_00393 1.9e-141 glpQ 3.1.4.46 C phosphodiesterase
COKMIKJD_00394 3.1e-23 WQ51_02665 S Protein of unknown function (DUF3042)
COKMIKJD_00395 2.1e-70 yqhL P Rhodanese-like protein
COKMIKJD_00396 8.9e-181 glk 2.7.1.2 G Glucokinase
COKMIKJD_00397 9.3e-36 yqgQ S Bacterial protein of unknown function (DUF910)
COKMIKJD_00398 2e-118 gluP 3.4.21.105 S Peptidase, S54 family
COKMIKJD_00399 1e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COKMIKJD_00400 2.5e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COKMIKJD_00401 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
COKMIKJD_00402 1.8e-25 CP_0775 S Domain of unknown function (DUF378)
COKMIKJD_00403 0.0 S membrane
COKMIKJD_00404 1.7e-56 yneR S Belongs to the HesB IscA family
COKMIKJD_00405 6.3e-71 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COKMIKJD_00406 1e-119 udk 2.7.1.48 F Cytidine monophosphokinase
COKMIKJD_00407 1.2e-205 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
COKMIKJD_00408 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COKMIKJD_00409 5.8e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COKMIKJD_00410 3.9e-68 yodB K Transcriptional regulator, HxlR family
COKMIKJD_00411 4e-92 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
COKMIKJD_00412 9.4e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COKMIKJD_00413 8.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
COKMIKJD_00414 3.1e-135 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COKMIKJD_00415 1.2e-70 S Protein of unknown function (DUF1093)
COKMIKJD_00416 3.2e-292 arlS 2.7.13.3 T Histidine kinase
COKMIKJD_00417 2.8e-120 K response regulator
COKMIKJD_00418 1.9e-194 adhP 1.1.1.1 C alcohol dehydrogenase
COKMIKJD_00419 8e-94 zmp3 O Zinc-dependent metalloprotease
COKMIKJD_00420 9e-09 zmp3 O Zinc-dependent metalloprotease
COKMIKJD_00421 9.7e-52 K Transcriptional regulator, ArsR family
COKMIKJD_00422 3.9e-145 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
COKMIKJD_00423 6.9e-29 rpmF J Belongs to the bacterial ribosomal protein bL32 family
COKMIKJD_00424 8.6e-96 yceD S Uncharacterized ACR, COG1399
COKMIKJD_00425 5.6e-214 ylbM S Belongs to the UPF0348 family
COKMIKJD_00426 1.5e-140 yqeM Q Methyltransferase
COKMIKJD_00427 1.6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COKMIKJD_00428 1.8e-107 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
COKMIKJD_00429 5.9e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COKMIKJD_00430 2.9e-48 yhbY J RNA-binding protein
COKMIKJD_00431 1.9e-222 yqeH S Ribosome biogenesis GTPase YqeH
COKMIKJD_00432 3.2e-103 yqeG S HAD phosphatase, family IIIA
COKMIKJD_00433 3.7e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COKMIKJD_00434 5.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
COKMIKJD_00435 4.4e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COKMIKJD_00436 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COKMIKJD_00437 2.9e-165 dnaI L Primosomal protein DnaI
COKMIKJD_00438 3.6e-244 dnaB L replication initiation and membrane attachment
COKMIKJD_00439 7.8e-88 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COKMIKJD_00440 7e-110 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COKMIKJD_00441 1.1e-163 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COKMIKJD_00442 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COKMIKJD_00443 6.4e-262 guaD 3.5.4.3 F Amidohydrolase family
COKMIKJD_00444 3.9e-235 F Permease
COKMIKJD_00445 7.1e-119 ybhL S Belongs to the BI1 family
COKMIKJD_00446 6.2e-134 pnuC H nicotinamide mononucleotide transporter
COKMIKJD_00447 4.3e-258 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
COKMIKJD_00448 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
COKMIKJD_00449 6.5e-173
COKMIKJD_00450 4.9e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COKMIKJD_00451 6.5e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
COKMIKJD_00452 5.8e-280 E amino acid
COKMIKJD_00453 8.9e-107 dhaS K Bacterial regulatory proteins, tetR family
COKMIKJD_00454 3.8e-17 1.1.1.1 C nadph quinone reductase
COKMIKJD_00457 6.5e-210 lmrP E Major Facilitator Superfamily
COKMIKJD_00458 5.5e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COKMIKJD_00459 1.1e-286 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COKMIKJD_00460 6.7e-165
COKMIKJD_00461 2e-75 nreC K PFAM regulatory protein LuxR
COKMIKJD_00462 1.8e-78 comP 2.7.13.3 F Sensor histidine kinase
COKMIKJD_00463 2.9e-101 hipB K Helix-turn-helix
COKMIKJD_00464 3.5e-36 yitW S Iron-sulfur cluster assembly protein
COKMIKJD_00465 8.8e-254 sufB O assembly protein SufB
COKMIKJD_00466 1.5e-59 nifU C SUF system FeS assembly protein, NifU family
COKMIKJD_00467 4.5e-185 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COKMIKJD_00468 2e-135 sufD O FeS assembly protein SufD
COKMIKJD_00469 2e-125 sufC O FeS assembly ATPase SufC
COKMIKJD_00470 1.9e-12 feoA P FeoA domain
COKMIKJD_00471 4.6e-256 feoB P transporter of a GTP-driven Fe(2 ) uptake system
COKMIKJD_00472 5.6e-183 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
COKMIKJD_00473 3.4e-212 preA 1.3.1.1 C 4Fe-4S dicluster domain
COKMIKJD_00474 6.4e-67 S Protein of unknown function (DUF1097)
COKMIKJD_00475 8.8e-262 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
COKMIKJD_00476 7.1e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
COKMIKJD_00477 8.9e-57 ydiI Q Thioesterase superfamily
COKMIKJD_00478 3.7e-85 yybC S Protein of unknown function (DUF2798)
COKMIKJD_00479 4.2e-30 S AAA domain
COKMIKJD_00480 8.7e-42 S Bacterial toxin of type II toxin-antitoxin system, YafQ
COKMIKJD_00481 6.7e-36 S RelB antitoxin
COKMIKJD_00482 1.2e-129
COKMIKJD_00483 1.7e-54 S protein encoded in hypervariable junctions of pilus gene clusters
COKMIKJD_00484 3.3e-131 qmcA O prohibitin homologues
COKMIKJD_00485 5.7e-228 XK27_06930 S ABC-2 family transporter protein
COKMIKJD_00486 2.8e-114 K Bacterial regulatory proteins, tetR family
COKMIKJD_00487 3.1e-303 E Bacterial extracellular solute-binding proteins, family 5 Middle
COKMIKJD_00488 8.3e-77 gtrA S GtrA-like protein
COKMIKJD_00489 1.6e-76 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
COKMIKJD_00490 4.7e-89 cadD P Cadmium resistance transporter
COKMIKJD_00492 4.9e-97 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
COKMIKJD_00493 4.9e-176 draG 3.2.2.24 O ADP-ribosylglycohydrolase
COKMIKJD_00494 4.4e-140 nlhH I Esterase
COKMIKJD_00495 1.3e-35 mgrA K helix_turn_helix multiple antibiotic resistance protein
COKMIKJD_00496 8.7e-81 argO S LysE type translocator
COKMIKJD_00497 1.4e-119 lsa S ABC transporter
COKMIKJD_00498 2.9e-103 S regulation of response to stimulus
COKMIKJD_00499 2.2e-142 ydhO 3.4.14.13 M NlpC/P60 family
COKMIKJD_00502 2.8e-11 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
COKMIKJD_00503 3.4e-105 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COKMIKJD_00504 1.9e-166
COKMIKJD_00505 4.6e-86
COKMIKJD_00507 1.3e-45 K Acetyltransferase (GNAT) domain
COKMIKJD_00508 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
COKMIKJD_00510 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COKMIKJD_00511 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COKMIKJD_00512 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COKMIKJD_00513 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COKMIKJD_00514 1.1e-253 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COKMIKJD_00515 7.8e-57 yabR J RNA binding
COKMIKJD_00516 9.7e-44 divIC D Septum formation initiator
COKMIKJD_00517 1.6e-39 yabO J S4 domain protein
COKMIKJD_00518 9.1e-292 yabM S Polysaccharide biosynthesis protein
COKMIKJD_00519 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COKMIKJD_00520 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COKMIKJD_00521 1.1e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COKMIKJD_00522 9.6e-253 S Putative peptidoglycan binding domain
COKMIKJD_00524 1.1e-113 S (CBS) domain
COKMIKJD_00525 8.1e-61 ndoA L Toxic component of a toxin-antitoxin (TA) module
COKMIKJD_00527 8.1e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COKMIKJD_00528 2.9e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COKMIKJD_00529 2.2e-210 S nuclear-transcribed mRNA catabolic process, no-go decay
COKMIKJD_00530 2.1e-240 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COKMIKJD_00531 1e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COKMIKJD_00532 1.9e-149
COKMIKJD_00533 6.8e-143 htpX O Belongs to the peptidase M48B family
COKMIKJD_00534 9.9e-95 lemA S LemA family
COKMIKJD_00535 4.6e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COKMIKJD_00536 1e-251 XK27_00720 S Leucine-rich repeat (LRR) protein
COKMIKJD_00537 1.9e-19 XK27_00720 S Leucine-rich repeat (LRR) protein
COKMIKJD_00538 3.9e-32 XK27_00720 S Leucine-rich repeat (LRR) protein
COKMIKJD_00539 8.3e-92 XK27_00720 S regulation of response to stimulus
COKMIKJD_00540 1.4e-41 S Cell surface protein
COKMIKJD_00541 9.5e-49 S Cell surface protein
COKMIKJD_00542 1.2e-27 S WxL domain surface cell wall-binding
COKMIKJD_00543 2.2e-16 S WxL domain surface cell wall-binding
COKMIKJD_00545 7.6e-80 XK27_00720 S regulation of response to stimulus
COKMIKJD_00546 6e-10 S WxL domain surface cell wall-binding
COKMIKJD_00547 1.6e-10 S WxL domain surface cell wall-binding
COKMIKJD_00548 2.4e-16 S WxL domain surface cell wall-binding
COKMIKJD_00549 8.7e-117 srtA 3.4.22.70 M sortase family
COKMIKJD_00550 4.3e-42 rpmE2 J Ribosomal protein L31
COKMIKJD_00551 1.1e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COKMIKJD_00552 7.8e-151 L Transposase and inactivated derivatives, IS30 family
COKMIKJD_00553 1.2e-23 S Family of unknown function (DUF5388)
COKMIKJD_00554 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
COKMIKJD_00555 8.3e-37 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COKMIKJD_00556 6.2e-31
COKMIKJD_00558 7.1e-75 cinA 3.5.1.42 S Competence-damaged protein
COKMIKJD_00559 4.4e-40
COKMIKJD_00561 0.0 traA L MobA MobL family protein
COKMIKJD_00562 6.3e-194 L Psort location Cytoplasmic, score
COKMIKJD_00563 2e-92 3.1.21.3 V Type I restriction modification DNA specificity domain
COKMIKJD_00564 4.1e-303 hsdM 2.1.1.72 V type I restriction-modification system
COKMIKJD_00565 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
COKMIKJD_00566 8.7e-60
COKMIKJD_00567 2e-52
COKMIKJD_00568 1.5e-247 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
COKMIKJD_00571 1.9e-101 tnpR L Resolvase, N terminal domain
COKMIKJD_00572 7.4e-132 S Phage Mu protein F like protein
COKMIKJD_00573 1.2e-12 ytgB S Transglycosylase associated protein
COKMIKJD_00574 2e-41 S Domain of unknown function (DUF4355)
COKMIKJD_00575 4.2e-08 S Domain of unknown function (DUF4355)
COKMIKJD_00576 1.1e-36 gpG
COKMIKJD_00577 1.1e-51 tnp2PF3 L manually curated
COKMIKJD_00578 7.4e-16 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COKMIKJD_00580 4.8e-221 S Calcineurin-like phosphoesterase
COKMIKJD_00581 9.2e-57 asnB 6.3.5.4 E Asparagine synthase
COKMIKJD_00591 1.2e-07
COKMIKJD_00601 7.3e-233 N Uncharacterized conserved protein (DUF2075)
COKMIKJD_00602 9e-92 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
COKMIKJD_00603 6e-137 yhfI S Metallo-beta-lactamase superfamily
COKMIKJD_00604 3e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COKMIKJD_00605 1e-112 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COKMIKJD_00606 7.9e-106 T EAL domain
COKMIKJD_00607 3.3e-86
COKMIKJD_00608 5.8e-164 pgaC GT2 M Glycosyl transferase
COKMIKJD_00609 1.1e-59 pgaC GT2 M Glycosyl transferase
COKMIKJD_00610 9.1e-101 ytqB J Putative rRNA methylase
COKMIKJD_00611 5.1e-116 pgpB1 3.6.1.27 I Acid phosphatase homologues
COKMIKJD_00612 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COKMIKJD_00613 1.3e-46
COKMIKJD_00614 7.2e-121 P ABC-type multidrug transport system ATPase component
COKMIKJD_00615 1.8e-144 S NADPH-dependent FMN reductase
COKMIKJD_00616 4.4e-52
COKMIKJD_00617 1.5e-297 ytgP S Polysaccharide biosynthesis protein
COKMIKJD_00618 9.3e-124 rluB 5.4.99.19, 5.4.99.20, 5.4.99.21, 5.4.99.22 J pseudouridine synthase activity
COKMIKJD_00619 4.3e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COKMIKJD_00620 2.6e-266 pepV 3.5.1.18 E dipeptidase PepV
COKMIKJD_00621 4.5e-83 uspA T Belongs to the universal stress protein A family
COKMIKJD_00622 2.6e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
COKMIKJD_00623 4.4e-242 cycA E Amino acid permease
COKMIKJD_00624 2e-55 ytzB S Small secreted protein
COKMIKJD_00625 4e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
COKMIKJD_00626 1.4e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COKMIKJD_00627 5.8e-84 3.1.21.3 V Type I restriction modification DNA specificity domain
COKMIKJD_00628 1.4e-193 L Psort location Cytoplasmic, score
COKMIKJD_00629 0.0 traA L MobA MobL family protein
COKMIKJD_00630 7.2e-27
COKMIKJD_00631 3.1e-41
COKMIKJD_00632 1.6e-77
COKMIKJD_00633 3.3e-43 relB L Addiction module antitoxin, RelB DinJ family
COKMIKJD_00634 6.6e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
COKMIKJD_00635 3.5e-45 tnp2PF3 L Transposase DDE domain
COKMIKJD_00636 1e-67 3.2.1.17 M hydrolase, family 25
COKMIKJD_00637 1.2e-07 3.2.1.17 M hydrolase, family 25
COKMIKJD_00638 1.3e-28 S Haemolysin XhlA
COKMIKJD_00640 3.1e-119 D Cellulose biosynthesis protein BcsQ
COKMIKJD_00642 7.9e-207 npr 1.11.1.1 C Pyridine nucleotide-disulphide oxidoreductase
COKMIKJD_00643 5.5e-245 glpT G Major Facilitator Superfamily
COKMIKJD_00644 2.3e-12 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
COKMIKJD_00645 2e-191 tra L Transposase and inactivated derivatives, IS30 family
COKMIKJD_00646 8.6e-130 EGP Major facilitator Superfamily
COKMIKJD_00648 2.6e-247 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COKMIKJD_00649 1.1e-54 L recombinase activity
COKMIKJD_00650 7.7e-27 S Bacterial toxin of type II toxin-antitoxin system, YafQ
COKMIKJD_00651 3.5e-32 K helix_turn_helix, arabinose operon control protein
COKMIKJD_00653 5.2e-153 L Phage integrase family
COKMIKJD_00654 1.7e-84 dps P Belongs to the Dps family
COKMIKJD_00655 2.8e-88
COKMIKJD_00656 2.9e-176 L Initiator Replication protein
COKMIKJD_00657 2.5e-29
COKMIKJD_00658 2.3e-107 L Integrase
COKMIKJD_00659 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
COKMIKJD_00660 5.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COKMIKJD_00661 4.8e-193 ybfG M peptidoglycan-binding domain-containing protein
COKMIKJD_00662 2.6e-153 S Conjugative transposon protein TcpC
COKMIKJD_00663 0.0 tetP J Elongation factor G, domain IV
COKMIKJD_00664 1.1e-66 tnpR1 L Resolvase, N terminal domain
COKMIKJD_00665 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
COKMIKJD_00666 7.7e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
COKMIKJD_00667 1.5e-130 S haloacid dehalogenase-like hydrolase
COKMIKJD_00668 1.1e-211 L Transposase
COKMIKJD_00669 9.7e-150 yihY S Virulence factor BrkB
COKMIKJD_00670 2.5e-44 L COG3547 Transposase and inactivated derivatives
COKMIKJD_00671 7.1e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
COKMIKJD_00672 4.3e-86 K PFAM helix-turn-helix- domain containing protein AraC type
COKMIKJD_00673 5.7e-138 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COKMIKJD_00674 7.4e-61 ybjD L DNA synthesis involved in DNA repair
COKMIKJD_00675 6.9e-44
COKMIKJD_00676 1.7e-176 L Initiator Replication protein
COKMIKJD_00677 3.1e-62
COKMIKJD_00678 3e-99 L Integrase
COKMIKJD_00679 1.1e-226 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COKMIKJD_00680 1.1e-43 ahpC 1.11.1.15 O Peroxiredoxin
COKMIKJD_00681 3.2e-46 ahpC 1.11.1.15 O Peroxiredoxin
COKMIKJD_00682 2.7e-55
COKMIKJD_00683 2.1e-109 ylbE GM NAD(P)H-binding
COKMIKJD_00684 3.7e-44
COKMIKJD_00685 2.3e-68 K Helix-turn-helix XRE-family like proteins
COKMIKJD_00687 5.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COKMIKJD_00688 1.8e-69 K Transcriptional regulator
COKMIKJD_00689 1.9e-74 elaA S Gnat family
COKMIKJD_00690 6.7e-46
COKMIKJD_00691 8.9e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COKMIKJD_00692 1.6e-131 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
COKMIKJD_00693 2.4e-302 M Mycoplasma protein of unknown function, DUF285
COKMIKJD_00694 6.8e-72
COKMIKJD_00695 5.9e-26 K Transcriptional
COKMIKJD_00696 9.6e-222 LO Uncharacterized conserved protein (DUF2075)
COKMIKJD_00697 5.1e-116 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
COKMIKJD_00698 1.5e-123
COKMIKJD_00699 3.2e-107 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
COKMIKJD_00701 1.2e-200 pmrB EGP Major facilitator Superfamily
COKMIKJD_00702 2.2e-72 S COG NOG18757 non supervised orthologous group
COKMIKJD_00703 1.4e-231 EK Aminotransferase, class I
COKMIKJD_00704 0.0 tetP J elongation factor G
COKMIKJD_00705 3.8e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
COKMIKJD_00706 8.7e-153 yhaZ L DNA alkylation repair enzyme
COKMIKJD_00707 4.1e-119 yihL K UTRA
COKMIKJD_00708 2.8e-185 yegU O ADP-ribosylglycohydrolase
COKMIKJD_00709 2.8e-252 F Belongs to the purine-cytosine permease (2.A.39) family
COKMIKJD_00710 1e-146 G Belongs to the carbohydrate kinase PfkB family
COKMIKJD_00711 3.5e-171 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
COKMIKJD_00712 9.1e-130 S Protein of unknown function
COKMIKJD_00713 1.1e-215 naiP EGP Major facilitator Superfamily
COKMIKJD_00714 6.5e-120 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COKMIKJD_00715 5.1e-108 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COKMIKJD_00716 3.9e-136 S Belongs to the UPF0246 family
COKMIKJD_00717 3.9e-10
COKMIKJD_00719 1.4e-15 L Transposase
COKMIKJD_00720 1.5e-30 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COKMIKJD_00721 1.3e-303 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
COKMIKJD_00722 3.1e-153 K Transcriptional regulator
COKMIKJD_00723 5.2e-13 yjdF S Protein of unknown function (DUF2992)
COKMIKJD_00724 2.4e-13 S Transglycosylase associated protein
COKMIKJD_00725 8.8e-38
COKMIKJD_00726 1.9e-228 3.6.4.13 M domain protein
COKMIKJD_00727 1.9e-299 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
COKMIKJD_00728 4.5e-155 EG EamA-like transporter family
COKMIKJD_00729 4.3e-26
COKMIKJD_00730 2.2e-205 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
COKMIKJD_00733 1.3e-38
COKMIKJD_00734 1.9e-236 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COKMIKJD_00735 0.0 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
COKMIKJD_00736 4.4e-261 E Amino acid permease
COKMIKJD_00737 2.9e-236 nhaC C Na H antiporter NhaC
COKMIKJD_00738 5.6e-197 ptcA 2.1.3.3, 2.1.3.6 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COKMIKJD_00739 1.2e-231 aguD E Amino Acid
COKMIKJD_00740 7.4e-216 aguA 3.5.3.12 E agmatine deiminase
COKMIKJD_00741 3.7e-163 arcC 2.7.2.2 E Belongs to the carbamate kinase family
COKMIKJD_00742 5.2e-217 aguA 3.5.3.12 E agmatine deiminase
COKMIKJD_00743 1.2e-146 K Helix-turn-helix domain, rpiR family
COKMIKJD_00744 1.9e-161 mleR K LysR family
COKMIKJD_00745 2.9e-309 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
COKMIKJD_00746 1.5e-167 mleP S Sodium Bile acid symporter family
COKMIKJD_00747 6.3e-82 thiW S Thiamine-precursor transporter protein (ThiW)
COKMIKJD_00748 5.8e-206 ynfM EGP Major facilitator Superfamily
COKMIKJD_00749 1.3e-85 ygfC K Bacterial regulatory proteins, tetR family
COKMIKJD_00750 3.1e-179 hrtB V ABC transporter permease
COKMIKJD_00751 5.1e-122 devA 3.6.3.25 V ABC transporter, ATP-binding protein
COKMIKJD_00752 6.6e-222 EGP Major facilitator Superfamily
COKMIKJD_00753 5.4e-118 S GyrI-like small molecule binding domain
COKMIKJD_00754 1.1e-94 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COKMIKJD_00755 2.4e-220 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
COKMIKJD_00756 2.2e-171 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COKMIKJD_00757 5.8e-118 yeiL K Cyclic nucleotide-monophosphate binding domain
COKMIKJD_00758 1.5e-177 rihB 3.2.2.1, 3.2.2.8 F Nucleoside
COKMIKJD_00759 1.3e-212 mccF V LD-carboxypeptidase
COKMIKJD_00760 3.4e-67 K Transcriptional regulator, HxlR family
COKMIKJD_00761 2.4e-12
COKMIKJD_00762 1e-223 C Oxidoreductase
COKMIKJD_00763 3.9e-184 mdt(A) EGP Major facilitator Superfamily
COKMIKJD_00764 1.5e-115
COKMIKJD_00765 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
COKMIKJD_00766 1.1e-261 G Major Facilitator
COKMIKJD_00767 5.2e-176 K Transcriptional regulator, LacI family
COKMIKJD_00768 1.2e-08
COKMIKJD_00769 4.9e-82
COKMIKJD_00770 7.8e-302 E ABC transporter, substratebinding protein
COKMIKJD_00771 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
COKMIKJD_00772 9.1e-95 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COKMIKJD_00773 4.1e-31 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
COKMIKJD_00774 8.3e-45 S CRISPR-associated protein (Cas_Csn2)
COKMIKJD_00775 1.3e-249 xylP2 G symporter
COKMIKJD_00776 5.9e-194 nlhH_1 I alpha/beta hydrolase fold
COKMIKJD_00777 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
COKMIKJD_00778 1.1e-18 S integral membrane protein
COKMIKJD_00779 3.6e-146 G Belongs to the phosphoglycerate mutase family
COKMIKJD_00780 1e-98 speG J Acetyltransferase (GNAT) domain
COKMIKJD_00781 4.8e-51 sugE P Multidrug resistance protein
COKMIKJD_00782 1.8e-48 ykkC P Small Multidrug Resistance protein
COKMIKJD_00783 1.4e-74
COKMIKJD_00784 6.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
COKMIKJD_00785 2.8e-185 tdh 1.1.1.14 C Zinc-binding dehydrogenase
COKMIKJD_00786 3.6e-140 S Membrane
COKMIKJD_00787 6.8e-71 4.4.1.5 E Glyoxalase
COKMIKJD_00788 9e-259 norG_2 K Aminotransferase class I and II
COKMIKJD_00789 2.6e-138 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H Phosphomethylpyrimidine kinase
COKMIKJD_00790 6.8e-84 hmpT S ECF-type riboflavin transporter, S component
COKMIKJD_00791 1e-99 ywlG S Belongs to the UPF0340 family
COKMIKJD_00792 6.1e-29 mcbG S Pentapeptide repeats (8 copies)
COKMIKJD_00793 7.9e-177 K helix_turn _helix lactose operon repressor
COKMIKJD_00795 3.9e-157 rihA F Inosine-uridine preferring nucleoside hydrolase
COKMIKJD_00796 9.2e-116 yoaK S Protein of unknown function (DUF1275)
COKMIKJD_00797 1.6e-302 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
COKMIKJD_00798 5.8e-145 yfiQ I Acyltransferase family
COKMIKJD_00799 1e-178 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
COKMIKJD_00800 5.6e-114 ssuA P NMT1-like family
COKMIKJD_00801 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
COKMIKJD_00802 0.0 yjcE P Sodium proton antiporter
COKMIKJD_00803 1.9e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COKMIKJD_00804 8.8e-44
COKMIKJD_00805 1.2e-169 panE2 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COKMIKJD_00806 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
COKMIKJD_00807 6.1e-58 K Helix-turn-helix domain
COKMIKJD_00809 1e-290 ytgP S Polysaccharide biosynthesis protein
COKMIKJD_00810 3.8e-84 iap CBM50 M NlpC P60 family
COKMIKJD_00811 1.6e-177 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COKMIKJD_00812 1.1e-112
COKMIKJD_00813 1.3e-102 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
COKMIKJD_00814 3.8e-111 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
COKMIKJD_00815 2.8e-76 K Winged helix DNA-binding domain
COKMIKJD_00816 2.6e-50
COKMIKJD_00818 6.3e-166 S DNA/RNA non-specific endonuclease
COKMIKJD_00820 2e-27
COKMIKJD_00821 3.4e-16
COKMIKJD_00823 8.5e-254 frlA E Amino acid permease
COKMIKJD_00824 1.3e-157 nanK 2.7.1.2 GK ROK family
COKMIKJD_00825 2.4e-251 brnQ U Component of the transport system for branched-chain amino acids
COKMIKJD_00826 6.2e-175 S DUF218 domain
COKMIKJD_00827 1.5e-163
COKMIKJD_00828 1.2e-73 K Transcriptional regulator
COKMIKJD_00829 0.0 pepF2 E Oligopeptidase F
COKMIKJD_00830 1.2e-174 D Alpha beta
COKMIKJD_00831 9.6e-121 yoaK S Protein of unknown function (DUF1275)
COKMIKJD_00832 1e-277 rny S Endoribonuclease that initiates mRNA decay
COKMIKJD_00833 1.2e-244 rarA L recombination factor protein RarA
COKMIKJD_00834 3.8e-159 akr5f 1.1.1.346 C Aldo keto reductase
COKMIKJD_00835 1.7e-221 xylR GK ROK family
COKMIKJD_00836 9.8e-132 K helix_turn_helix, mercury resistance
COKMIKJD_00837 9.4e-134 XK27_00890 S Domain of unknown function (DUF368)
COKMIKJD_00838 1.2e-81 P CorA-like Mg2+ transporter protein
COKMIKJD_00839 5.2e-27 K Helix-turn-helix XRE-family like proteins
COKMIKJD_00841 4e-30
COKMIKJD_00845 3.4e-91
COKMIKJD_00846 9.4e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COKMIKJD_00847 1.3e-114 ybbL S ABC transporter, ATP-binding protein
COKMIKJD_00848 2.8e-129 ybbM S Uncharacterised protein family (UPF0014)
COKMIKJD_00849 7.3e-147 vdlC S Enoyl-(Acyl carrier protein) reductase
COKMIKJD_00850 2e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
COKMIKJD_00851 2.3e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COKMIKJD_00852 4e-108 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
COKMIKJD_00853 1.1e-286 macB3 V ABC transporter, ATP-binding protein
COKMIKJD_00854 2e-196 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
COKMIKJD_00855 1.2e-52
COKMIKJD_00856 4.5e-59
COKMIKJD_00857 5.7e-208
COKMIKJD_00858 3.4e-100 K DNA-templated transcription, initiation
COKMIKJD_00859 2.3e-27
COKMIKJD_00860 6.2e-11 S Protein of unknown function (DUF2922)
COKMIKJD_00861 3.1e-167 K LysR substrate binding domain
COKMIKJD_00862 2.4e-215 EK Aminotransferase, class I
COKMIKJD_00863 2.4e-86
COKMIKJD_00864 4.3e-88
COKMIKJD_00865 2.8e-276
COKMIKJD_00867 2.2e-98
COKMIKJD_00868 2.7e-34
COKMIKJD_00869 2.8e-61 K HxlR-like helix-turn-helix
COKMIKJD_00870 4.1e-40
COKMIKJD_00871 3.3e-82
COKMIKJD_00872 6.3e-44
COKMIKJD_00873 2.2e-111 GM NmrA-like family
COKMIKJD_00874 1.4e-150 5.4.2.7 G Metalloenzyme superfamily
COKMIKJD_00875 2e-225 nupG F Nucleoside
COKMIKJD_00876 9.8e-215 pbuO_1 S Permease family
COKMIKJD_00877 2.8e-168 rihC 3.2.2.1, 3.2.2.8 F Nucleoside
COKMIKJD_00878 7.8e-160 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
COKMIKJD_00879 3.7e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
COKMIKJD_00880 6.4e-143 noc K Belongs to the ParB family
COKMIKJD_00881 4.1e-136 soj D Sporulation initiation inhibitor
COKMIKJD_00882 3.4e-155 spo0J K Belongs to the ParB family
COKMIKJD_00883 8.5e-33 yyzM S Bacterial protein of unknown function (DUF951)
COKMIKJD_00884 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COKMIKJD_00885 2.6e-132 XK27_01040 S Protein of unknown function (DUF1129)
COKMIKJD_00886 1.9e-101
COKMIKJD_00887 3.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COKMIKJD_00888 3.5e-123 K response regulator
COKMIKJD_00889 2.4e-209 hpk31 2.7.13.3 T Histidine kinase
COKMIKJD_00890 2.9e-235 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COKMIKJD_00891 1.2e-162 V domain protein
COKMIKJD_00892 4e-35
COKMIKJD_00893 3.6e-249 gor 1.8.1.7 C Glutathione reductase
COKMIKJD_00894 6.6e-87 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
COKMIKJD_00895 7.2e-136 azlC E AzlC protein
COKMIKJD_00896 1.3e-52 azlD S branched-chain amino acid
COKMIKJD_00897 1.2e-235 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
COKMIKJD_00898 8.8e-122
COKMIKJD_00899 1.3e-210 xylR GK ROK family
COKMIKJD_00900 2.3e-169 K AI-2E family transporter
COKMIKJD_00901 2.4e-257 M domain protein
COKMIKJD_00902 1.2e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COKMIKJD_00903 2.4e-78 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
COKMIKJD_00904 1.7e-38
COKMIKJD_00905 5.8e-34 S Protein of unknown function (DUF3781)
COKMIKJD_00907 2.2e-16 K helix_turn_helix, mercury resistance
COKMIKJD_00908 1.5e-68 yobT S PFAM Metallo-beta-lactamase superfamily
COKMIKJD_00909 1.5e-221 EGP Major facilitator Superfamily
COKMIKJD_00910 3.6e-158 3.1.3.48 T Tyrosine phosphatase family
COKMIKJD_00911 2e-190 yjcE P Sodium proton antiporter
COKMIKJD_00912 8.5e-105 thiJ-2 3.5.1.124 S DJ-1/PfpI family
COKMIKJD_00913 4.6e-208 ykiI
COKMIKJD_00915 3.5e-260 ytjP 3.5.1.18 E Dipeptidase
COKMIKJD_00916 1.2e-280 arcD S C4-dicarboxylate anaerobic carrier
COKMIKJD_00917 6.5e-148 KT YcbB domain
COKMIKJD_00918 5.3e-221 2.1.1.80, 2.7.13.3, 3.1.1.61 T histidine kinase DNA gyrase B
COKMIKJD_00919 5.7e-278 S C4-dicarboxylate anaerobic carrier
COKMIKJD_00920 7.7e-238 arcA 3.5.3.6 E Arginine
COKMIKJD_00921 3.3e-197 argF 2.1.3.3, 2.1.3.6, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COKMIKJD_00922 5e-257 arcD E Arginine ornithine antiporter
COKMIKJD_00923 6.8e-217 arcT 2.6.1.1 E Aminotransferase
COKMIKJD_00924 4.1e-170 arcC 2.7.2.2 E Belongs to the carbamate kinase family
COKMIKJD_00925 3.3e-121 iprA K Cyclic nucleotide-monophosphate binding domain
COKMIKJD_00926 3.1e-130 XK27_07210 6.1.1.6 S B3 4 domain
COKMIKJD_00927 1.4e-66 lysM M LysM domain
COKMIKJD_00928 2.9e-94 laaE K Transcriptional regulator PadR-like family
COKMIKJD_00929 4.4e-182 chaT1 U Major Facilitator Superfamily
COKMIKJD_00930 1.9e-270 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
COKMIKJD_00931 3.6e-155
COKMIKJD_00932 4.4e-18 S Transglycosylase associated protein
COKMIKJD_00933 1.4e-90
COKMIKJD_00934 5.9e-25
COKMIKJD_00935 3.6e-70 asp S Asp23 family, cell envelope-related function
COKMIKJD_00936 7.4e-60 asp2 S Asp23 family, cell envelope-related function
COKMIKJD_00937 4.4e-64 hxlR K HxlR-like helix-turn-helix
COKMIKJD_00938 2.4e-130 ydfG S KR domain
COKMIKJD_00940 3.3e-100
COKMIKJD_00941 4.7e-156 map 3.4.11.18 E Methionine Aminopeptidase
COKMIKJD_00942 5.6e-144 S Sucrose-6F-phosphate phosphohydrolase
COKMIKJD_00943 5e-202 bcr1 EGP Major facilitator Superfamily
COKMIKJD_00944 6.8e-128 S haloacid dehalogenase-like hydrolase
COKMIKJD_00945 6.9e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
COKMIKJD_00946 2.3e-173 3.5.2.6 V Beta-lactamase enzyme family
COKMIKJD_00947 1.9e-62 yvoA_1 K Transcriptional regulator, GntR family
COKMIKJD_00948 4.3e-124 skfE V ATPases associated with a variety of cellular activities
COKMIKJD_00949 2.4e-120
COKMIKJD_00950 1.9e-136 3.1.3.48 T Tyrosine phosphatase family
COKMIKJD_00951 5.3e-114 S membrane transporter protein
COKMIKJD_00952 2e-97 rmaB K Transcriptional regulator, MarR family
COKMIKJD_00953 0.0 lmrA 3.6.3.44 V ABC transporter
COKMIKJD_00954 7.8e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
COKMIKJD_00955 6.8e-102 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
COKMIKJD_00956 4.5e-292 epsA I PAP2 superfamily
COKMIKJD_00957 2.3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
COKMIKJD_00958 1e-159 K LysR substrate binding domain
COKMIKJD_00959 1.8e-281 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
COKMIKJD_00960 6.3e-94 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
COKMIKJD_00961 1.5e-68
COKMIKJD_00962 5.2e-159 P ABC-type cobalt transport system permease component CbiQ and related transporters
COKMIKJD_00963 6.2e-307 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
COKMIKJD_00964 1.4e-113 S ECF-type riboflavin transporter, S component
COKMIKJD_00965 3.8e-177 U FFAT motif binding
COKMIKJD_00966 1.2e-57 S Domain of unknown function (DUF4430)
COKMIKJD_00967 1.7e-59 K helix_turn_helix, arabinose operon control protein
COKMIKJD_00968 1.9e-40 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
COKMIKJD_00969 7.2e-122 C Oxidoreductase
COKMIKJD_00970 1.1e-193 EGP Major facilitator Superfamily
COKMIKJD_00971 1.4e-199 EGP Major facilitator Superfamily
COKMIKJD_00972 2.9e-159 dkgB S reductase
COKMIKJD_00973 8.4e-224
COKMIKJD_00974 1.2e-09 K MarR family
COKMIKJD_00975 2e-100 yobS K Bacterial regulatory proteins, tetR family
COKMIKJD_00976 1.1e-72 K helix_turn_helix, mercury resistance
COKMIKJD_00977 2.5e-79 yphH S Cupin domain
COKMIKJD_00978 6.2e-54 yphJ 4.1.1.44 S decarboxylase
COKMIKJD_00979 2.1e-205 G Glycosyl hydrolases family 8
COKMIKJD_00980 2.9e-168 XK27_00880 3.5.1.28 M hydrolase, family 25
COKMIKJD_00981 6.8e-146 S Zinc-dependent metalloprotease
COKMIKJD_00982 5.1e-104 tag 3.2.2.20 L glycosylase
COKMIKJD_00983 4.1e-209 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
COKMIKJD_00984 4.5e-306 sbcC L Putative exonuclease SbcCD, C subunit
COKMIKJD_00985 2.8e-190 pva1 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
COKMIKJD_00986 0.0 3.2.1.21 GH3 G hydrolase, family 3
COKMIKJD_00988 0.0 E ABC transporter, substratebinding protein
COKMIKJD_00989 4.4e-100 tag 3.2.2.20 L glycosylase
COKMIKJD_00990 3.5e-146 P Belongs to the nlpA lipoprotein family
COKMIKJD_00991 2e-194 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COKMIKJD_00992 1.1e-113 metI P ABC transporter permease
COKMIKJD_00993 1e-176 EG EamA-like transporter family
COKMIKJD_00994 1e-31
COKMIKJD_00995 3.3e-183 tas C Aldo/keto reductase family
COKMIKJD_00996 4.5e-64 gcvH E glycine cleavage
COKMIKJD_00997 5.6e-189 6.3.1.20 H Lipoate-protein ligase
COKMIKJD_00998 1.3e-51
COKMIKJD_00999 0.0 pelX M domain, Protein
COKMIKJD_01000 6.8e-298 E Bacterial extracellular solute-binding proteins, family 5 Middle
COKMIKJD_01001 5.7e-219 mutY L A G-specific adenine glycosylase
COKMIKJD_01002 4.4e-52
COKMIKJD_01003 1.8e-107 XK27_00220 S Dienelactone hydrolase family
COKMIKJD_01004 2.1e-31 cspC K Cold shock protein
COKMIKJD_01005 3e-37 S Cytochrome B5
COKMIKJD_01007 6.2e-30
COKMIKJD_01009 7.9e-123 yrkL S Flavodoxin-like fold
COKMIKJD_01010 5.2e-18
COKMIKJD_01011 9.3e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COKMIKJD_01012 2e-46
COKMIKJD_01013 3.2e-239 codA 3.5.4.1 F cytosine deaminase
COKMIKJD_01014 6.6e-84
COKMIKJD_01015 1.3e-142 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COKMIKJD_01016 2.5e-83 S 3-demethylubiquinone-9 3-methyltransferase
COKMIKJD_01017 2.7e-114 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
COKMIKJD_01018 6.2e-264 U Belongs to the BCCT transporter (TC 2.A.15) family
COKMIKJD_01019 7.4e-77 usp1 T Universal stress protein family
COKMIKJD_01020 3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S HAD-hyrolase-like
COKMIKJD_01021 7.5e-70 yeaO S Protein of unknown function, DUF488
COKMIKJD_01022 1.8e-118 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
COKMIKJD_01023 4.2e-158 hipB K Helix-turn-helix
COKMIKJD_01024 1.8e-138 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
COKMIKJD_01025 1.9e-152 map 3.4.11.18 E Methionine Aminopeptidase
COKMIKJD_01026 2.3e-23
COKMIKJD_01027 4e-246 EGP Major facilitator Superfamily
COKMIKJD_01028 3.1e-80 6.3.3.2 S ASCH
COKMIKJD_01029 0.0 oppD EP Psort location Cytoplasmic, score
COKMIKJD_01030 1.8e-173 etfA C Electron transfer flavoprotein FAD-binding domain
COKMIKJD_01031 1e-142 etfB C Electron transfer flavoprotein domain
COKMIKJD_01032 1.6e-205 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
COKMIKJD_01033 3e-120 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
COKMIKJD_01034 1.6e-101 GM NAD(P)H-binding
COKMIKJD_01035 2.6e-51 K helix_turn_helix, mercury resistance
COKMIKJD_01036 4.7e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
COKMIKJD_01037 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COKMIKJD_01038 2.6e-36
COKMIKJD_01039 1.9e-248 gph G Transporter
COKMIKJD_01040 5.1e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COKMIKJD_01041 3.1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COKMIKJD_01042 3.6e-282 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
COKMIKJD_01043 1.6e-185 galR K Transcriptional regulator
COKMIKJD_01046 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
COKMIKJD_01047 2.8e-91 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
COKMIKJD_01048 0.0 pepO 3.4.24.71 O Peptidase family M13
COKMIKJD_01049 1.5e-86 K helix_turn_helix multiple antibiotic resistance protein
COKMIKJD_01050 1.3e-130
COKMIKJD_01051 2.8e-82 uspA T Belongs to the universal stress protein A family
COKMIKJD_01053 1.2e-200 yibE S overlaps another CDS with the same product name
COKMIKJD_01054 1e-126 yibF S overlaps another CDS with the same product name
COKMIKJD_01056 4.7e-167 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
COKMIKJD_01057 5.7e-91 perR P Belongs to the Fur family
COKMIKJD_01058 1.9e-113 S VIT family
COKMIKJD_01059 2.3e-117 S membrane
COKMIKJD_01060 1e-295 E amino acid
COKMIKJD_01061 7.7e-79 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COKMIKJD_01062 6.6e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
COKMIKJD_01063 1.5e-177 sepS16B
COKMIKJD_01064 2.5e-124
COKMIKJD_01065 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
COKMIKJD_01066 3.1e-43
COKMIKJD_01067 2.3e-30
COKMIKJD_01068 1.2e-230 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
COKMIKJD_01069 5.2e-212 P Belongs to the ABC transporter superfamily
COKMIKJD_01070 1.3e-246 G Bacterial extracellular solute-binding protein
COKMIKJD_01071 1e-151 U Binding-protein-dependent transport system inner membrane component
COKMIKJD_01072 5.8e-141 U Binding-protein-dependent transport system inner membrane component
COKMIKJD_01075 5.7e-129 L Transposase and inactivated derivatives, IS30 family
COKMIKJD_01076 4.3e-40
COKMIKJD_01077 6.9e-93
COKMIKJD_01078 1.9e-23 S Small integral membrane protein (DUF2273)
COKMIKJD_01079 4.2e-71 S cog cog1302
COKMIKJD_01080 1.3e-11 S Transglycosylase associated protein
COKMIKJD_01081 3.8e-16
COKMIKJD_01082 2e-88 L Transposase and inactivated derivatives, IS30 family
COKMIKJD_01083 1.5e-56 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COKMIKJD_01084 1.5e-60 K UTRA
COKMIKJD_01085 6.4e-84 dps P Belongs to the Dps family
COKMIKJD_01086 3.9e-104
COKMIKJD_01087 3.3e-115 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
COKMIKJD_01088 2.2e-90 L Transposase and inactivated derivatives, IS30 family
COKMIKJD_01089 4.1e-30 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
COKMIKJD_01090 5.7e-129 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COKMIKJD_01091 3.9e-106 tnp L DDE domain
COKMIKJD_01094 6e-79 yybA 2.3.1.57 K Transcriptional regulator
COKMIKJD_01095 1e-75 elaA S Gnat family
COKMIKJD_01096 2.2e-82 padR K Virulence activator alpha C-term
COKMIKJD_01097 1.2e-102 padC Q Phenolic acid decarboxylase
COKMIKJD_01098 9.8e-85 F NUDIX domain
COKMIKJD_01100 5.9e-94 wecD K Acetyltransferase (GNAT) family
COKMIKJD_01101 4.8e-87 M Belongs to the glycosyl hydrolase 28 family
COKMIKJD_01102 1.2e-123 yliE T Putative diguanylate phosphodiesterase
COKMIKJD_01103 1.2e-101 XK27_06935 K Bacterial regulatory proteins, tetR family
COKMIKJD_01104 2.3e-171 S ABC-2 family transporter protein
COKMIKJD_01105 3.7e-123 malR3 K cheY-homologous receiver domain
COKMIKJD_01106 1.1e-265 yufL 2.7.13.3 T Single cache domain 3
COKMIKJD_01107 3.9e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COKMIKJD_01108 2.3e-190 S Membrane transport protein
COKMIKJD_01109 1e-249 nhaC C Na H antiporter NhaC
COKMIKJD_01110 3e-93 Z012_06855 S Acetyltransferase (GNAT) family
COKMIKJD_01111 1.4e-68
COKMIKJD_01112 3.5e-171 C Aldo keto reductase
COKMIKJD_01113 2.3e-49
COKMIKJD_01114 9.6e-122 kcsA P Ion channel
COKMIKJD_01115 5.9e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COKMIKJD_01116 3.9e-95 yxkA S Phosphatidylethanolamine-binding protein
COKMIKJD_01117 1.3e-88 uspA T universal stress protein
COKMIKJD_01118 0.0 S membrane
COKMIKJD_01119 2.6e-64 frataxin S Domain of unknown function (DU1801)
COKMIKJD_01120 4.3e-141 IQ reductase
COKMIKJD_01121 1.1e-224 xylT EGP Major facilitator Superfamily
COKMIKJD_01122 4.8e-290 xylB 2.7.1.12, 2.7.1.16, 2.7.1.17 G Xylulose kinase
COKMIKJD_01123 3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
COKMIKJD_01124 7.8e-10
COKMIKJD_01126 6.9e-49
COKMIKJD_01127 2.3e-69
COKMIKJD_01128 3.9e-195 lplA 6.3.1.20 H Lipoate-protein ligase
COKMIKJD_01129 1.6e-79 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
COKMIKJD_01130 6.9e-192 oppD P Belongs to the ABC transporter superfamily
COKMIKJD_01131 1.6e-177 oppF P Belongs to the ABC transporter superfamily
COKMIKJD_01132 9.8e-180 oppB P ABC transporter permease
COKMIKJD_01133 1e-173 oppC EP Binding-protein-dependent transport system inner membrane component
COKMIKJD_01134 0.0 oppA1 E ABC transporter substrate-binding protein
COKMIKJD_01135 1.5e-49 K transcriptional regulator
COKMIKJD_01136 1.2e-175 norB EGP Major Facilitator
COKMIKJD_01137 1.3e-53 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COKMIKJD_01138 1.4e-75 uspA T universal stress protein
COKMIKJD_01139 6.7e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COKMIKJD_01141 1.1e-127 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
COKMIKJD_01142 1.8e-211 2.1.1.80, 2.7.13.3, 3.1.1.61 T protein histidine kinase activity
COKMIKJD_01143 4.6e-204 2.7.13.3 T GHKL domain
COKMIKJD_01144 3.4e-135 plnC K LytTr DNA-binding domain
COKMIKJD_01145 3.3e-71
COKMIKJD_01146 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COKMIKJD_01147 1.3e-109 O Zinc-dependent metalloprotease
COKMIKJD_01148 7.5e-132 gntR1 K UbiC transcription regulator-associated domain protein
COKMIKJD_01149 9.9e-91 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COKMIKJD_01150 8.6e-129
COKMIKJD_01151 4.2e-64 S Leucine-rich repeat (LRR) protein
COKMIKJD_01153 2.2e-19 K Helix-turn-helix XRE-family like proteins
COKMIKJD_01154 1.9e-20 S Protein of unknown function (DUF3278)
COKMIKJD_01155 2.9e-249 EGP Major facilitator Superfamily
COKMIKJD_01157 1.8e-226 S module of peptide synthetase
COKMIKJD_01158 4e-294 uxaC 5.3.1.12 G glucuronate isomerase
COKMIKJD_01159 4.8e-309 5.1.2.7 S tagaturonate epimerase
COKMIKJD_01160 7.8e-277 yjmB G MFS/sugar transport protein
COKMIKJD_01161 1.7e-182 exuR K Periplasmic binding protein domain
COKMIKJD_01162 4.4e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
COKMIKJD_01163 5.7e-129 kdgR K FCD domain
COKMIKJD_01164 1.1e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
COKMIKJD_01165 1.3e-303 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
COKMIKJD_01166 5.3e-189 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COKMIKJD_01167 2.3e-119 pgm3 G Belongs to the phosphoglycerate mutase family
COKMIKJD_01168 3.3e-166 yqhA G Aldose 1-epimerase
COKMIKJD_01169 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
COKMIKJD_01170 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
COKMIKJD_01171 0.0 yicI 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
COKMIKJD_01172 1.4e-259 gph G MFS/sugar transport protein
COKMIKJD_01173 3.5e-282 uxaC 5.3.1.12 G glucuronate isomerase
COKMIKJD_01174 5.8e-247 V Polysaccharide biosynthesis C-terminal domain
COKMIKJD_01175 1.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
COKMIKJD_01176 8.8e-167 yjjC V ABC transporter
COKMIKJD_01177 2.6e-281 M Exporter of polyketide antibiotics
COKMIKJD_01178 2e-51 DR0488 S 3D domain
COKMIKJD_01179 7.3e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COKMIKJD_01180 5.7e-175 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
COKMIKJD_01181 6.4e-167 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
COKMIKJD_01182 1.9e-95 K Bacterial regulatory proteins, tetR family
COKMIKJD_01184 2.5e-56 M LysM domain
COKMIKJD_01186 2.5e-54 M LysM domain protein
COKMIKJD_01187 7.5e-42 M LysM domain protein
COKMIKJD_01188 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
COKMIKJD_01189 0.0 glpQ 3.1.4.46 C phosphodiesterase
COKMIKJD_01190 2.2e-93 M1-874 K Domain of unknown function (DUF1836)
COKMIKJD_01191 0.0 yfgQ P E1-E2 ATPase
COKMIKJD_01193 3.6e-162 ytbE 1.1.1.346 S Aldo keto reductase
COKMIKJD_01194 1.3e-260 yjeM E Amino Acid
COKMIKJD_01195 1.4e-74 hsp O Belongs to the small heat shock protein (HSP20) family
COKMIKJD_01196 7.6e-61
COKMIKJD_01197 9.7e-242 yhdP S Transporter associated domain
COKMIKJD_01198 1.8e-173 K Transcriptional regulator, LacI family
COKMIKJD_01199 7.7e-143 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COKMIKJD_01201 7.8e-250 lmrB EGP Major facilitator Superfamily
COKMIKJD_01202 1.2e-253 S ATPases associated with a variety of cellular activities
COKMIKJD_01203 2.6e-85 nrdI F Belongs to the NrdI family
COKMIKJD_01204 5.7e-135 nfrA 1.5.1.39 C nitroreductase
COKMIKJD_01205 4.2e-245 glpT G Major Facilitator Superfamily
COKMIKJD_01206 1.5e-214 yttB EGP Major facilitator Superfamily
COKMIKJD_01207 2.2e-87
COKMIKJD_01208 2.1e-157 1.1.1.65 C Aldo keto reductase
COKMIKJD_01209 1e-90 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
COKMIKJD_01210 2.4e-93 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
COKMIKJD_01211 3.1e-64 K Bacterial regulatory proteins, tetR family
COKMIKJD_01212 2.4e-238 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
COKMIKJD_01213 2.3e-61 cas1 L CRISPR associated protein Cas1
COKMIKJD_01214 1.2e-22 cas2 L CRISPR associated protein Cas2
COKMIKJD_01215 0.0 S PglZ domain
COKMIKJD_01216 1.6e-235 V Type II restriction enzyme, methylase subunits
COKMIKJD_01217 1.1e-44 L Belongs to the 'phage' integrase family
COKMIKJD_01218 8.5e-90 L Belongs to the 'phage' integrase family
COKMIKJD_01219 0.0 2.1.1.72 LV Eco57I restriction-modification methylase
COKMIKJD_01220 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
COKMIKJD_01221 6.1e-84 S Domain of unknown function (DUF1788)
COKMIKJD_01222 7.4e-69 S Putative inner membrane protein (DUF1819)
COKMIKJD_01223 1.5e-96 S Protein of unknown function C-terminus (DUF2399)
COKMIKJD_01224 9.3e-280 D Putative exonuclease SbcCD, C subunit
COKMIKJD_01225 8.4e-105
COKMIKJD_01226 1.9e-137
COKMIKJD_01227 7.8e-34
COKMIKJD_01228 4.6e-72 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
COKMIKJD_01229 5.8e-158 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M MucBP domain
COKMIKJD_01230 1.3e-86 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COKMIKJD_01231 1.2e-63 1.6.5.2 S NADPH-dependent FMN reductase
COKMIKJD_01233 1.2e-22 T Cyclic nucleotide-binding domain
COKMIKJD_01234 3.6e-138 S Alpha/beta hydrolase family
COKMIKJD_01236 6.9e-179 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
COKMIKJD_01237 5.2e-49 C Flavodoxin
COKMIKJD_01238 8.4e-57 adhR K MerR, DNA binding
COKMIKJD_01239 6.2e-77 GM NmrA-like family
COKMIKJD_01240 1.1e-102 S Alpha beta hydrolase
COKMIKJD_01241 7.6e-62 yliE T EAL domain
COKMIKJD_01242 2.6e-27 K helix_turn_helix, mercury resistance
COKMIKJD_01243 1.1e-49 K Bacterial regulatory proteins, tetR family
COKMIKJD_01244 3.6e-13 1.1.1.219 GM Male sterility protein
COKMIKJD_01245 9.2e-113 1.1.1.219 GM Male sterility protein
COKMIKJD_01246 2.4e-170 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
COKMIKJD_01247 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
COKMIKJD_01248 4.1e-69 K Transcriptional regulator
COKMIKJD_01249 7.3e-94 qorB 1.6.5.2 GM NmrA-like family
COKMIKJD_01251 3.3e-138 K Helix-turn-helix domain
COKMIKJD_01252 1.7e-165
COKMIKJD_01253 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
COKMIKJD_01254 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COKMIKJD_01255 3.8e-215 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COKMIKJD_01256 4e-184 xynD 3.5.1.104 G polysaccharide deacetylase
COKMIKJD_01257 1.3e-58
COKMIKJD_01258 4.6e-103 GM NAD(P)H-binding
COKMIKJD_01259 3.4e-180 iolS C Aldo keto reductase
COKMIKJD_01260 2.2e-227 pbuG S permease
COKMIKJD_01261 1.8e-15 K toxin-antitoxin pair type II binding
COKMIKJD_01262 7.1e-22
COKMIKJD_01263 7.2e-92 K helix_turn_helix multiple antibiotic resistance protein
COKMIKJD_01264 8.4e-160 drrA V ABC transporter
COKMIKJD_01265 1.5e-114 drrB U ABC-2 type transporter
COKMIKJD_01266 1.6e-99 K LysR substrate binding domain
COKMIKJD_01267 1.3e-91 S Protein of unknown function (DUF554)
COKMIKJD_01268 1.8e-167 2.5.1.74 H UbiA prenyltransferase family
COKMIKJD_01269 0.0 S Bacterial membrane protein YfhO
COKMIKJD_01270 1.2e-86 ccl S QueT transporter
COKMIKJD_01272 5.3e-54 L Transposase
COKMIKJD_01274 1.3e-29 M hydrolase, family 25
COKMIKJD_01275 0.0 S Predicted membrane protein (DUF2207)
COKMIKJD_01276 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
COKMIKJD_01277 5.2e-281 xynT G MFS/sugar transport protein
COKMIKJD_01278 4.5e-150 rhaS2 K Transcriptional regulator, AraC family
COKMIKJD_01279 1.8e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COKMIKJD_01280 5.2e-22
COKMIKJD_01281 2.8e-143 F DNA/RNA non-specific endonuclease
COKMIKJD_01282 3.8e-88
COKMIKJD_01285 4.2e-171 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
COKMIKJD_01286 5.5e-153 xynB 3.2.1.37 GH43 K family 39
COKMIKJD_01287 1.5e-115 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
COKMIKJD_01288 1.6e-115 G MFS/sugar transport protein
COKMIKJD_01289 2.5e-233 aguA 3.2.1.139 G Glycosyl hydrolase 67
COKMIKJD_01291 1.2e-51
COKMIKJD_01292 8.5e-111 L haloacid dehalogenase-like hydrolase
COKMIKJD_01293 4.6e-252 pepC 3.4.22.40 E aminopeptidase
COKMIKJD_01294 8.9e-78 K helix_turn_helix multiple antibiotic resistance protein
COKMIKJD_01295 5.5e-109 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COKMIKJD_01296 3.7e-205 tcaB EGP Major facilitator Superfamily
COKMIKJD_01297 4.5e-222 S module of peptide synthetase
COKMIKJD_01298 1.6e-91 ykhA 3.1.2.20 I Thioesterase superfamily
COKMIKJD_01299 5.2e-98 J Acetyltransferase (GNAT) domain
COKMIKJD_01300 1.8e-113 ywnB S NAD(P)H-binding
COKMIKJD_01301 5.5e-245 brnQ U Component of the transport system for branched-chain amino acids
COKMIKJD_01302 3.7e-36
COKMIKJD_01303 2.6e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
COKMIKJD_01304 3e-37
COKMIKJD_01305 5.7e-54
COKMIKJD_01306 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COKMIKJD_01307 9.3e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COKMIKJD_01308 2.9e-110 jag S R3H domain protein
COKMIKJD_01309 1e-145 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COKMIKJD_01310 3.2e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COKMIKJD_01311 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
COKMIKJD_01312 1.7e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COKMIKJD_01313 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COKMIKJD_01314 2e-35 yaaA S S4 domain protein YaaA
COKMIKJD_01315 1.7e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COKMIKJD_01316 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COKMIKJD_01317 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COKMIKJD_01318 1.9e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
COKMIKJD_01319 3e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COKMIKJD_01320 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COKMIKJD_01321 4.1e-228 Q Imidazolonepropionase and related amidohydrolases
COKMIKJD_01322 7.6e-302 E ABC transporter, substratebinding protein
COKMIKJD_01323 1.4e-136
COKMIKJD_01324 4.5e-227 Q Imidazolonepropionase and related amidohydrolases
COKMIKJD_01325 5.8e-302 E ABC transporter, substratebinding protein
COKMIKJD_01326 1.1e-98 K Bacterial regulatory proteins, tetR family
COKMIKJD_01327 2.5e-74 S membrane transporter protein
COKMIKJD_01328 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
COKMIKJD_01329 2.1e-63 rplI J Binds to the 23S rRNA
COKMIKJD_01331 6e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COKMIKJD_01332 1.1e-100 S NADPH-dependent FMN reductase
COKMIKJD_01333 3.1e-212 yttB EGP Major facilitator Superfamily
COKMIKJD_01334 1.8e-22
COKMIKJD_01335 9e-303 E ABC transporter, substratebinding protein
COKMIKJD_01336 1.3e-38
COKMIKJD_01337 9.3e-29 E Matrixin
COKMIKJD_01338 5.8e-62 E Matrixin
COKMIKJD_01340 5.7e-132 K response regulator
COKMIKJD_01341 0.0 vicK 2.7.13.3 T Histidine kinase
COKMIKJD_01342 3.7e-238 yycH S YycH protein
COKMIKJD_01343 5.5e-150 yycI S YycH protein
COKMIKJD_01344 3.4e-157 vicX 3.1.26.11 S domain protein
COKMIKJD_01345 3e-187 htrA 3.4.21.107 O serine protease
COKMIKJD_01346 7.3e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COKMIKJD_01347 1.3e-08 V endonuclease activity
COKMIKJD_01349 3.2e-11 S Mor transcription activator family
COKMIKJD_01353 6.4e-39 V Domain of unknown function (DUF3883)
COKMIKJD_01354 9.4e-28 V Domain of unknown function (DUF3883)
COKMIKJD_01356 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COKMIKJD_01357 4.3e-36 ykuJ S Protein of unknown function (DUF1797)
COKMIKJD_01358 1.2e-183 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COKMIKJD_01359 1e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
COKMIKJD_01360 6.1e-224 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
COKMIKJD_01361 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COKMIKJD_01362 7.2e-40 ptsH G phosphocarrier protein HPR
COKMIKJD_01363 4.5e-30
COKMIKJD_01364 0.0 clpE O Belongs to the ClpA ClpB family
COKMIKJD_01365 2.1e-202 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
COKMIKJD_01366 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
COKMIKJD_01367 8.6e-281 pipD E Dipeptidase
COKMIKJD_01368 1.1e-256 nox 1.6.3.4 C NADH oxidase
COKMIKJD_01369 8.3e-272 XK27_00720 S Leucine-rich repeat (LRR) protein
COKMIKJD_01370 6.5e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COKMIKJD_01371 5e-88
COKMIKJD_01372 0.0 2.7.8.12 M glycerophosphotransferase
COKMIKJD_01373 5.2e-151
COKMIKJD_01374 2.6e-76 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
COKMIKJD_01375 1.4e-180 yueF S AI-2E family transporter
COKMIKJD_01376 4.4e-108 ygaC J Belongs to the UPF0374 family
COKMIKJD_01377 5.6e-39 S Bacteriocin-protection, YdeI or OmpD-Associated
COKMIKJD_01378 3.1e-212 pbpX2 V Beta-lactamase
COKMIKJD_01379 7.5e-141 recX 2.4.1.337 GT4 S Regulatory protein RecX
COKMIKJD_01380 1e-78 fld C Flavodoxin
COKMIKJD_01381 2e-158 yihY S Belongs to the UPF0761 family
COKMIKJD_01382 1.8e-156 S Nuclease-related domain
COKMIKJD_01383 5.9e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COKMIKJD_01384 4.2e-159 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
COKMIKJD_01385 1.2e-231 gntP EG Gluconate
COKMIKJD_01386 1.6e-76 T Universal stress protein family
COKMIKJD_01389 6.2e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
COKMIKJD_01390 1.5e-186 mocA S Oxidoreductase
COKMIKJD_01391 5.7e-64 S Domain of unknown function (DUF4828)
COKMIKJD_01392 6e-140 lys M Glycosyl hydrolases family 25
COKMIKJD_01393 4.4e-147 gntR K rpiR family
COKMIKJD_01394 1.6e-301 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
COKMIKJD_01395 3.7e-209 gntP EG Gluconate
COKMIKJD_01396 4.7e-233 potE E amino acid
COKMIKJD_01397 5.3e-248 fucP G Major Facilitator Superfamily
COKMIKJD_01398 2.5e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
COKMIKJD_01399 1.4e-292 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
COKMIKJD_01400 2.5e-239 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
COKMIKJD_01401 1.2e-172 deoR K sugar-binding domain protein
COKMIKJD_01402 1.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
COKMIKJD_01403 3.8e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
COKMIKJD_01404 1.3e-120 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
COKMIKJD_01405 5.1e-37 cro K Helix-turn-helix XRE-family like proteins
COKMIKJD_01406 1e-57 K Helix-turn-helix XRE-family like proteins
COKMIKJD_01407 7.8e-143 3.1.3.48 T Pfam:Y_phosphatase3C
COKMIKJD_01408 1.2e-191 C Oxidoreductase
COKMIKJD_01409 1.7e-54 pduU E BMC
COKMIKJD_01410 1.6e-219 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COKMIKJD_01411 6.9e-209 pduQ C Iron-containing alcohol dehydrogenase
COKMIKJD_01412 3e-265 pduP 1.2.1.87 C Aldehyde dehydrogenase family
COKMIKJD_01413 4e-69 pduO S Haem-degrading
COKMIKJD_01414 7.6e-103 pduO 2.5.1.17 S Cobalamin adenosyltransferase
COKMIKJD_01415 3e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
COKMIKJD_01416 2.5e-89 S Putative propanediol utilisation
COKMIKJD_01417 6.1e-114 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
COKMIKJD_01418 4.9e-42 pduA_4 CQ BMC
COKMIKJD_01419 8.2e-82 pduK CQ BMC
COKMIKJD_01420 1.3e-57 pduH S Dehydratase medium subunit
COKMIKJD_01421 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
COKMIKJD_01422 3e-90 pduE 4.2.1.28 Q Dehydratase small subunit
COKMIKJD_01423 8.5e-128 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
COKMIKJD_01424 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
COKMIKJD_01425 4.1e-130 pduB E BMC
COKMIKJD_01426 5.2e-41 pduA_4 CQ BMC
COKMIKJD_01427 6.9e-206 K helix_turn_helix, arabinose operon control protein
COKMIKJD_01428 4.7e-131 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COKMIKJD_01429 3.3e-42 eutP E Ethanolamine utilisation - propanediol utilisation
COKMIKJD_01430 1.8e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COKMIKJD_01431 1.3e-185 yegS 2.7.1.107 G Lipid kinase
COKMIKJD_01432 6.5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COKMIKJD_01433 2.7e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COKMIKJD_01434 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COKMIKJD_01435 1.9e-193 camS S sex pheromone
COKMIKJD_01436 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COKMIKJD_01437 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
COKMIKJD_01438 8.6e-215 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COKMIKJD_01439 5.1e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COKMIKJD_01440 2.1e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
COKMIKJD_01441 2.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COKMIKJD_01442 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
COKMIKJD_01443 9.1e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
COKMIKJD_01444 1.1e-173 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
COKMIKJD_01445 4.6e-282 cydA 1.10.3.14 C ubiquinol oxidase
COKMIKJD_01446 3.3e-180 pdxB EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
COKMIKJD_01447 1.1e-144 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COKMIKJD_01448 2e-157 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COKMIKJD_01449 4.2e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
COKMIKJD_01450 1.3e-252 yfnA E Amino Acid
COKMIKJD_01451 1.2e-196 asnA 6.3.1.1 F aspartate--ammonia ligase
COKMIKJD_01452 5.3e-116 ktrA P domain protein
COKMIKJD_01453 3.1e-240 ktrB P Potassium uptake protein
COKMIKJD_01454 6e-193 manA 5.3.1.8 G mannose-6-phosphate isomerase
COKMIKJD_01455 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
COKMIKJD_01456 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COKMIKJD_01457 4.2e-152 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COKMIKJD_01458 6.1e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COKMIKJD_01459 2.4e-161 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COKMIKJD_01460 2.9e-151 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COKMIKJD_01461 7.4e-62 rplQ J Ribosomal protein L17
COKMIKJD_01462 9.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COKMIKJD_01463 7.5e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COKMIKJD_01464 1.3e-60 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COKMIKJD_01465 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COKMIKJD_01466 3.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COKMIKJD_01467 1.2e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COKMIKJD_01468 1.9e-69 rplO J Binds to the 23S rRNA
COKMIKJD_01469 3.8e-24 rpmD J Ribosomal protein L30
COKMIKJD_01470 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COKMIKJD_01471 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COKMIKJD_01472 3.9e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COKMIKJD_01473 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COKMIKJD_01474 2.1e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COKMIKJD_01475 1.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COKMIKJD_01476 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COKMIKJD_01477 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COKMIKJD_01478 4.8e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
COKMIKJD_01479 7.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COKMIKJD_01480 5.1e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COKMIKJD_01481 2.4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COKMIKJD_01482 1.8e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COKMIKJD_01483 6e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COKMIKJD_01484 2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COKMIKJD_01485 3.2e-107 rplD J Forms part of the polypeptide exit tunnel
COKMIKJD_01486 6.1e-117 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COKMIKJD_01487 8.9e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
COKMIKJD_01488 3.1e-232 mepA V MATE efflux family protein
COKMIKJD_01489 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COKMIKJD_01490 3.2e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COKMIKJD_01491 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COKMIKJD_01492 1.1e-110 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
COKMIKJD_01493 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COKMIKJD_01494 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COKMIKJD_01495 3.6e-103 K Bacterial regulatory proteins, tetR family
COKMIKJD_01496 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COKMIKJD_01497 9.9e-77 ctsR K Belongs to the CtsR family
COKMIKJD_01506 1.3e-211 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COKMIKJD_01507 9.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
COKMIKJD_01508 1.1e-275 lysP E amino acid
COKMIKJD_01509 1.4e-24 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COKMIKJD_01510 6.9e-131 I alpha/beta hydrolase fold
COKMIKJD_01511 1e-119 lssY 3.6.1.27 I phosphatase
COKMIKJD_01512 1.2e-71 S Threonine/Serine exporter, ThrE
COKMIKJD_01513 3.1e-120 thrE S Putative threonine/serine exporter
COKMIKJD_01514 5.3e-121 sirR K iron dependent repressor
COKMIKJD_01515 1.2e-158 czcD P cation diffusion facilitator family transporter
COKMIKJD_01516 4.3e-103 K Acetyltransferase (GNAT) domain
COKMIKJD_01517 2.7e-76 merR K MerR HTH family regulatory protein
COKMIKJD_01518 2.3e-268 lmrB EGP Major facilitator Superfamily
COKMIKJD_01519 3.6e-102 S Domain of unknown function (DUF4811)
COKMIKJD_01520 1e-37 yyaN K MerR HTH family regulatory protein
COKMIKJD_01521 8.2e-107 azlC E branched-chain amino acid
COKMIKJD_01522 1.4e-48 azlD S Branched-chain amino acid transport protein (AzlD)
COKMIKJD_01523 2.3e-232 pyrP F Permease
COKMIKJD_01524 3.2e-220 EGP Major facilitator Superfamily
COKMIKJD_01525 3.8e-69
COKMIKJD_01526 4.3e-89 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
COKMIKJD_01527 2.4e-104 3.2.2.20 K acetyltransferase
COKMIKJD_01528 1.5e-138 yejC S Protein of unknown function (DUF1003)
COKMIKJD_01529 6.3e-165 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
COKMIKJD_01530 2e-49 S Glycine cleavage H-protein
COKMIKJD_01533 1.7e-86 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
COKMIKJD_01534 1e-278 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
COKMIKJD_01535 9.2e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
COKMIKJD_01536 1.5e-305 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
COKMIKJD_01537 2.9e-249 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
COKMIKJD_01538 2.5e-195 araR K Transcriptional regulator
COKMIKJD_01539 4.1e-88 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
COKMIKJD_01540 1.1e-166 K transcriptional regulator, ArsR family
COKMIKJD_01541 2.3e-200 abf G Belongs to the glycosyl hydrolase 43 family
COKMIKJD_01542 6.9e-237 lacY G Oligosaccharide H symporter
COKMIKJD_01543 1.8e-297 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
COKMIKJD_01544 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
COKMIKJD_01545 2.1e-70 K Transcriptional regulator
COKMIKJD_01546 3.2e-93 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
COKMIKJD_01547 1.8e-278 pipD E Dipeptidase
COKMIKJD_01548 2.4e-263 arcD E Arginine ornithine antiporter
COKMIKJD_01549 0.0 pepN 3.4.11.2 E aminopeptidase
COKMIKJD_01550 4.3e-73 S Iron-sulphur cluster biosynthesis
COKMIKJD_01551 0.0 rafA 3.2.1.22 G alpha-galactosidase
COKMIKJD_01552 1.3e-52 bipA 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Leucine-rich repeat (LRR) protein
COKMIKJD_01553 5.5e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COKMIKJD_01554 2.7e-100 aacA4_1 4.1.1.17 K acetyltransferase
COKMIKJD_01555 7e-175 coaA 2.7.1.33 F Pantothenic acid kinase
COKMIKJD_01556 0.0 helD 3.6.4.12 L DNA helicase
COKMIKJD_01557 5e-289 yjbQ P TrkA C-terminal domain protein
COKMIKJD_01558 2.9e-119 G phosphoglycerate mutase
COKMIKJD_01559 4.4e-180 oppF P Belongs to the ABC transporter superfamily
COKMIKJD_01560 1.3e-204 oppD P Belongs to the ABC transporter superfamily
COKMIKJD_01561 2.2e-185 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
COKMIKJD_01562 2.2e-152 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
COKMIKJD_01563 6.3e-304 oppA E ABC transporter, substratebinding protein
COKMIKJD_01564 1.2e-302 oppA E ABC transporter, substratebinding protein
COKMIKJD_01565 1.3e-224 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COKMIKJD_01566 3.6e-109 glnP P ABC transporter permease
COKMIKJD_01567 1.1e-110 gluC P ABC transporter permease
COKMIKJD_01568 9.2e-150 glnH ET ABC transporter substrate-binding protein
COKMIKJD_01569 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COKMIKJD_01570 8.9e-170
COKMIKJD_01571 5.3e-13 3.2.1.14 GH18
COKMIKJD_01572 4.7e-79 zur P Belongs to the Fur family
COKMIKJD_01573 2.3e-75 gmk2 2.7.4.8 F Guanylate kinase
COKMIKJD_01574 1.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
COKMIKJD_01575 1.3e-241 yfnA E Amino Acid
COKMIKJD_01576 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COKMIKJD_01577 4.3e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
COKMIKJD_01579 4.6e-87 M ErfK YbiS YcfS YnhG
COKMIKJD_01580 6.7e-295 S ABC transporter, ATP-binding protein
COKMIKJD_01581 2e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COKMIKJD_01582 1.2e-126 XK27_07075 S CAAX protease self-immunity
COKMIKJD_01584 1.6e-11 M domain protein
COKMIKJD_01585 1.8e-119 cmpC S ATPases associated with a variety of cellular activities
COKMIKJD_01586 1.7e-168 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
COKMIKJD_01587 2.8e-166 XK27_00670 S ABC transporter
COKMIKJD_01588 1e-162 degV S Uncharacterised protein, DegV family COG1307
COKMIKJD_01589 2.9e-179 XK27_08835 S ABC transporter
COKMIKJD_01590 3e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
COKMIKJD_01591 3.3e-138 XK27_08845 S ABC transporter, ATP-binding protein
COKMIKJD_01593 6.2e-157 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
COKMIKJD_01594 1.5e-127 terC P integral membrane protein, YkoY family
COKMIKJD_01595 2.9e-243 pbpX1 V SH3-like domain
COKMIKJD_01596 1.5e-109 NU mannosyl-glycoprotein
COKMIKJD_01597 1.1e-181 S DUF218 domain
COKMIKJD_01598 1.4e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COKMIKJD_01599 4.5e-135 IQ reductase
COKMIKJD_01600 1.6e-14
COKMIKJD_01601 0.0 ydgH S MMPL family
COKMIKJD_01602 9.9e-253 ydiC1 EGP Major facilitator Superfamily
COKMIKJD_01603 2e-89 K Transcriptional regulator PadR-like family
COKMIKJD_01604 1e-81 merR K MerR family regulatory protein
COKMIKJD_01605 1.5e-61 iap CBM50 M NlpC P60 family
COKMIKJD_01606 1.3e-75 yjcF K protein acetylation
COKMIKJD_01607 6.4e-122 pgm3 G phosphoglycerate mutase family
COKMIKJD_01608 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COKMIKJD_01609 8.3e-182 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
COKMIKJD_01610 1.5e-143 S Alpha/beta hydrolase of unknown function (DUF915)
COKMIKJD_01611 2.7e-191 S Protease prsW family
COKMIKJD_01612 7e-178 iunH2 3.2.2.1, 3.2.2.8 F nucleoside hydrolase
COKMIKJD_01613 2.1e-07 yvlA
COKMIKJD_01614 7.6e-75
COKMIKJD_01615 2.4e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
COKMIKJD_01616 9.9e-149 S Alpha/beta hydrolase of unknown function (DUF915)
COKMIKJD_01617 5.4e-234 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COKMIKJD_01618 4e-73 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
COKMIKJD_01619 8.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
COKMIKJD_01620 3.4e-55 S LuxR family transcriptional regulator
COKMIKJD_01621 1.1e-126 cat 2.3.1.28 V Chloramphenicol acetyltransferase
COKMIKJD_01622 5e-218 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COKMIKJD_01623 9.8e-169 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COKMIKJD_01624 2.2e-94 S ABC transporter permease
COKMIKJD_01625 1.4e-254 P ABC transporter
COKMIKJD_01626 7.5e-115 P Cobalt transport protein
COKMIKJD_01627 2.7e-120 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
COKMIKJD_01628 6.6e-60
COKMIKJD_01629 1.1e-08
COKMIKJD_01631 2.3e-30
COKMIKJD_01632 1e-215
COKMIKJD_01633 3e-187 ansA 3.5.1.1 EJ Asparaginase
COKMIKJD_01634 3.2e-24
COKMIKJD_01635 4.7e-247 pbuX F xanthine permease
COKMIKJD_01636 8e-168 natA S ABC transporter, ATP-binding protein
COKMIKJD_01637 3.6e-211 natB CP ABC-2 family transporter protein
COKMIKJD_01639 1.8e-251 yjjP S Putative threonine/serine exporter
COKMIKJD_01640 1e-151 degV S Uncharacterised protein, DegV family COG1307
COKMIKJD_01641 2.9e-153 1.1.1.2, 1.1.1.307 C Aldo keto reductase
COKMIKJD_01642 3.4e-64 S Protein of unknown function (DUF1722)
COKMIKJD_01643 2.2e-68 yqeB S Pyrimidine dimer DNA glycosylase
COKMIKJD_01644 2.2e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
COKMIKJD_01645 1.7e-125 K Crp-like helix-turn-helix domain
COKMIKJD_01646 2.1e-238 larA 5.1.2.1 S Domain of unknown function (DUF2088)
COKMIKJD_01647 2.1e-132 cpmA S AIR carboxylase
COKMIKJD_01648 1.6e-227 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
COKMIKJD_01649 7.8e-149 larE S NAD synthase
COKMIKJD_01650 1.7e-122 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COKMIKJD_01651 1.4e-178 hoxN U High-affinity nickel-transport protein
COKMIKJD_01652 4.2e-42 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
COKMIKJD_01654 5.8e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COKMIKJD_01655 2.7e-239 mntH P H( )-stimulated, divalent metal cation uptake system
COKMIKJD_01656 1.7e-29
COKMIKJD_01657 2.3e-60 K Winged helix DNA-binding domain
COKMIKJD_01658 6.1e-252 S Uncharacterized protein conserved in bacteria (DUF2252)
COKMIKJD_01659 9.2e-278 frvR K Mga helix-turn-helix domain
COKMIKJD_01660 9.8e-36
COKMIKJD_01661 2.3e-254 U Belongs to the purine-cytosine permease (2.A.39) family
COKMIKJD_01662 4.9e-78 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
COKMIKJD_01663 7.8e-85 S Bacterial PH domain
COKMIKJD_01664 6e-266 ydbT S Bacterial PH domain
COKMIKJD_01665 5.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COKMIKJD_01666 2.7e-212 EG GntP family permease
COKMIKJD_01667 4.9e-193 KT Putative sugar diacid recognition
COKMIKJD_01668 6e-174
COKMIKJD_01669 1.2e-160 ytrB V ABC transporter, ATP-binding protein
COKMIKJD_01670 6.1e-61 ytrA K helix_turn_helix gluconate operon transcriptional repressor
COKMIKJD_01671 3.5e-121 S Protein of unknown function (DUF975)
COKMIKJD_01672 9.6e-132 XK27_07210 6.1.1.6 S B3/4 domain
COKMIKJD_01673 0.0 2.8.2.22 M Arylsulfotransferase Ig-like domain
COKMIKJD_01674 1.5e-19
COKMIKJD_01675 1.3e-176 xopQ 3.2.2.1, 3.2.2.8 F inosine-uridine preferring nucleoside hydrolase
COKMIKJD_01676 2.7e-166 ydcZ S Putative inner membrane exporter, YdcZ
COKMIKJD_01677 4.5e-311 ybiT S ABC transporter, ATP-binding protein
COKMIKJD_01678 4.4e-155 K helix_turn_helix, arabinose operon control protein
COKMIKJD_01679 1.9e-209 norA EGP Major facilitator Superfamily
COKMIKJD_01680 8.5e-154 K LysR substrate binding domain
COKMIKJD_01681 3e-158 MA20_14895 S Conserved hypothetical protein 698
COKMIKJD_01682 1.1e-102 P Cadmium resistance transporter
COKMIKJD_01683 1.6e-52 czrA K Transcriptional regulator, ArsR family
COKMIKJD_01684 0.0 mco Q Multicopper oxidase
COKMIKJD_01685 6.9e-119 S SNARE associated Golgi protein
COKMIKJD_01686 0.0 cadA P P-type ATPase
COKMIKJD_01687 1.9e-194 sdrF M Collagen binding domain
COKMIKJD_01688 2.7e-70 S Iron-sulphur cluster biosynthesis
COKMIKJD_01689 1.3e-60 gntR1 K Transcriptional regulator, GntR family
COKMIKJD_01690 0.0 Q FtsX-like permease family
COKMIKJD_01691 1.8e-136 cysA V ABC transporter, ATP-binding protein
COKMIKJD_01692 7.2e-183 S Aldo keto reductase
COKMIKJD_01693 3.9e-202 ytbD EGP Major facilitator Superfamily
COKMIKJD_01694 6.3e-63 K Transcriptional regulator, HxlR family
COKMIKJD_01695 3.7e-168
COKMIKJD_01696 0.0 2.7.8.12 M glycerophosphotransferase
COKMIKJD_01697 1.4e-72 K Transcriptional regulator
COKMIKJD_01698 5.9e-152 1.6.5.2 GM NmrA-like family
COKMIKJD_01699 1.9e-133 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COKMIKJD_01700 3.6e-151 3.2.1.37 GH43 K helix_turn_helix, arabinose operon control protein
COKMIKJD_01701 2.3e-311 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
COKMIKJD_01702 4e-218 G Major Facilitator
COKMIKJD_01703 2.1e-97 S membrane transporter protein
COKMIKJD_01704 2.3e-282 E dipeptidase activity
COKMIKJD_01705 2.5e-139 K acetyltransferase
COKMIKJD_01706 1.8e-131 iap CBM50 M NlpC/P60 family
COKMIKJD_01707 1.5e-71 spx4 1.20.4.1 P ArsC family
COKMIKJD_01708 1.7e-249 yclG M Parallel beta-helix repeats
COKMIKJD_01709 4.6e-64 K MarR family
COKMIKJD_01710 2.4e-150 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
COKMIKJD_01711 8.2e-151 S Alpha/beta hydrolase of unknown function (DUF915)
COKMIKJD_01712 5.4e-152 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
COKMIKJD_01713 2.3e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COKMIKJD_01714 5.4e-77
COKMIKJD_01715 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
COKMIKJD_01716 8.6e-254 malT G Major Facilitator
COKMIKJD_01717 7.5e-180 malR K Transcriptional regulator, LacI family
COKMIKJD_01718 1.1e-234 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
COKMIKJD_01719 1.8e-119 K cheY-homologous receiver domain
COKMIKJD_01720 0.0 S membrane
COKMIKJD_01722 5.5e-169 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COKMIKJD_01723 8.1e-28 S Protein of unknown function (DUF2929)
COKMIKJD_01724 8e-96 2.7.6.5 S RelA SpoT domain protein
COKMIKJD_01725 1.2e-225 mdtG EGP Major facilitator Superfamily
COKMIKJD_01726 7.8e-140 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
COKMIKJD_01727 2e-56 ywjH S Protein of unknown function (DUF1634)
COKMIKJD_01728 2.2e-143 yxaA S membrane transporter protein
COKMIKJD_01729 2.8e-154 lysR5 K LysR substrate binding domain
COKMIKJD_01730 8.8e-167 S Alpha/beta hydrolase of unknown function (DUF915)
COKMIKJD_01731 2.3e-248 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COKMIKJD_01732 1.7e-159
COKMIKJD_01733 5.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COKMIKJD_01734 1.4e-161 I Carboxylesterase family
COKMIKJD_01735 3.7e-146 M1-1017
COKMIKJD_01736 5.1e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COKMIKJD_01737 1.3e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COKMIKJD_01738 5.1e-38 yrkD S Metal-sensitive transcriptional repressor
COKMIKJD_01739 2.3e-56 trxA1 O Belongs to the thioredoxin family
COKMIKJD_01740 3.7e-268 nox C NADH oxidase
COKMIKJD_01741 4.1e-153 S Uncharacterised protein, DegV family COG1307
COKMIKJD_01742 2.4e-240 mntH P H( )-stimulated, divalent metal cation uptake system
COKMIKJD_01743 3.4e-127 IQ reductase
COKMIKJD_01744 4.1e-39
COKMIKJD_01745 4.2e-81 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
COKMIKJD_01746 1.5e-111 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
COKMIKJD_01747 5.9e-127 kdgT P 2-keto-3-deoxygluconate permease
COKMIKJD_01748 3.9e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COKMIKJD_01749 2.1e-146 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
COKMIKJD_01750 1.8e-09
COKMIKJD_01751 1.6e-100 K Bacterial transcriptional regulator
COKMIKJD_01752 3.5e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
COKMIKJD_01753 6.9e-62 K Bacterial regulatory proteins, tetR family
COKMIKJD_01754 6.8e-30 K Bacterial regulatory proteins, tetR family
COKMIKJD_01755 1.5e-89 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COKMIKJD_01756 9.3e-228 ndh 1.6.99.3 C NADH dehydrogenase
COKMIKJD_01757 8.1e-114 ylbE GM NAD(P)H-binding
COKMIKJD_01758 3e-26
COKMIKJD_01759 4.5e-126 K Transcriptional regulatory protein, C terminal
COKMIKJD_01760 4.1e-224 T PhoQ Sensor
COKMIKJD_01761 6.5e-43
COKMIKJD_01762 4.1e-66
COKMIKJD_01763 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COKMIKJD_01764 5.3e-151 corA P CorA-like Mg2+ transporter protein
COKMIKJD_01765 1.4e-136 pnuC H nicotinamide mononucleotide transporter
COKMIKJD_01766 8.6e-57 K Winged helix DNA-binding domain
COKMIKJD_01767 0.0 malL 3.2.1.10, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G Alpha amylase, catalytic domain protein
COKMIKJD_01768 6e-120 yclH V ABC transporter
COKMIKJD_01769 2.4e-161 yclI V FtsX-like permease family
COKMIKJD_01770 2e-195 yubA S AI-2E family transporter
COKMIKJD_01771 5.8e-104
COKMIKJD_01772 2.3e-243 M hydrolase, family 25
COKMIKJD_01773 3.1e-184 ykoT GT2 M Glycosyl transferase family 2
COKMIKJD_01774 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COKMIKJD_01775 1.8e-108 M Protein of unknown function (DUF3737)
COKMIKJD_01776 1.1e-228 patB 4.4.1.8 E Aminotransferase, class I
COKMIKJD_01777 1.6e-182 yfeX P Peroxidase
COKMIKJD_01778 7.8e-222 mdtG EGP Major facilitator Superfamily
COKMIKJD_01779 4.6e-45
COKMIKJD_01780 1.2e-222 opuCA E ABC transporter, ATP-binding protein
COKMIKJD_01781 8e-106 opuCB E ABC transporter permease
COKMIKJD_01782 1.1e-175 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COKMIKJD_01783 2.1e-109 opuCD P Binding-protein-dependent transport system inner membrane component
COKMIKJD_01784 5.1e-219
COKMIKJD_01785 8.4e-258
COKMIKJD_01786 2.5e-65 S Tautomerase enzyme
COKMIKJD_01787 0.0 uvrA2 L ABC transporter
COKMIKJD_01788 4.6e-99 S Protein of unknown function (DUF1440)
COKMIKJD_01789 1.4e-245 xylP1 G MFS/sugar transport protein
COKMIKJD_01790 1.4e-93 K helix_turn_helix multiple antibiotic resistance protein
COKMIKJD_01791 6.9e-34
COKMIKJD_01792 1.7e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
COKMIKJD_01793 2.4e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COKMIKJD_01794 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
COKMIKJD_01795 5.6e-122
COKMIKJD_01796 0.0 oatA I Acyltransferase
COKMIKJD_01797 3.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
COKMIKJD_01798 3.1e-158 xerD L Phage integrase, N-terminal SAM-like domain
COKMIKJD_01799 3.4e-152 yxkH G Polysaccharide deacetylase
COKMIKJD_01801 1.3e-63 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COKMIKJD_01802 0.0 ctpA 3.6.3.54 P P-type ATPase
COKMIKJD_01803 3.8e-159 S reductase
COKMIKJD_01804 3.4e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COKMIKJD_01805 1.5e-77 copR K Copper transport repressor CopY TcrY
COKMIKJD_01806 0.0 copB 3.6.3.4 P P-type ATPase
COKMIKJD_01807 3.8e-168 EG EamA-like transporter family
COKMIKJD_01808 6.1e-117 S Elongation factor G-binding protein, N-terminal
COKMIKJD_01809 2.1e-100 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
COKMIKJD_01810 6.4e-150
COKMIKJD_01811 3.4e-277 pipD E Dipeptidase
COKMIKJD_01813 1.6e-15 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COKMIKJD_01814 5.8e-89 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COKMIKJD_01815 2.2e-18
COKMIKJD_01816 0.0 pacL1 P P-type ATPase
COKMIKJD_01817 1.7e-71 K MarR family
COKMIKJD_01818 1.1e-98 S NADPH-dependent FMN reductase
COKMIKJD_01819 3.5e-197 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
COKMIKJD_01820 6.4e-12 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COKMIKJD_01821 4.2e-270 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COKMIKJD_01822 3.1e-162 opuBA E ABC transporter, ATP-binding protein
COKMIKJD_01823 2.2e-67 lrpA K AsnC family
COKMIKJD_01824 6e-188 adhP 1.1.1.1 C alcohol dehydrogenase
COKMIKJD_01825 5.8e-225 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COKMIKJD_01826 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
COKMIKJD_01827 4.7e-63 S WxL domain surface cell wall-binding
COKMIKJD_01828 4e-108
COKMIKJD_01829 1.9e-242 yifK E Amino acid permease
COKMIKJD_01830 4.3e-97 K Acetyltransferase (GNAT) domain
COKMIKJD_01831 6.3e-73 fld C Flavodoxin
COKMIKJD_01832 7.8e-219 fabV 1.3.1.44, 1.3.1.9 I NAD(P)H binding domain of trans-2-enoyl-CoA reductase
COKMIKJD_01833 1.6e-185 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COKMIKJD_01834 3.6e-110 S Putative adhesin
COKMIKJD_01835 5.3e-73 XK27_06920 S Protein of unknown function (DUF1700)
COKMIKJD_01836 1e-53 K Transcriptional regulator PadR-like family
COKMIKJD_01837 3.8e-104 pncA Q Isochorismatase family
COKMIKJD_01838 6e-160 G Peptidase_C39 like family
COKMIKJD_01839 8.6e-198 M NlpC/P60 family
COKMIKJD_01840 1.9e-115 ssuC U Binding-protein-dependent transport system inner membrane component
COKMIKJD_01841 7.7e-76 ssuB P ATPases associated with a variety of cellular activities
COKMIKJD_01843 4.3e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COKMIKJD_01844 1.4e-113 magIII L Base excision DNA repair protein, HhH-GPD family
COKMIKJD_01845 3.7e-38
COKMIKJD_01846 7.6e-132 puuD S peptidase C26
COKMIKJD_01847 1.2e-114 S Membrane
COKMIKJD_01848 0.0 O Pro-kumamolisin, activation domain
COKMIKJD_01849 5.7e-166 I Alpha beta
COKMIKJD_01850 2.6e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
COKMIKJD_01851 1.6e-179 D Alpha beta
COKMIKJD_01852 4.3e-98 fadR K Bacterial regulatory proteins, tetR family
COKMIKJD_01853 4e-122 GM NmrA-like family
COKMIKJD_01854 1.3e-240 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COKMIKJD_01855 3.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COKMIKJD_01856 8.5e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COKMIKJD_01857 8.3e-285 mntH P H( )-stimulated, divalent metal cation uptake system
COKMIKJD_01858 1.5e-71 T Universal stress protein family
COKMIKJD_01859 1.6e-120 sirR K Helix-turn-helix diphteria tox regulatory element
COKMIKJD_01860 7.2e-90 P Cadmium resistance transporter
COKMIKJD_01861 4.6e-73
COKMIKJD_01863 2e-19 L Integrase
COKMIKJD_01864 1.7e-38 S Antitoxin component of a toxin-antitoxin (TA) module
COKMIKJD_01867 1.7e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
COKMIKJD_01868 3.3e-297 dtpT U amino acid peptide transporter
COKMIKJD_01869 1.6e-148 yjjH S Calcineurin-like phosphoesterase
COKMIKJD_01872 1.2e-133 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COKMIKJD_01873 2.4e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
COKMIKJD_01874 1.9e-124 gntR1 K UbiC transcription regulator-associated domain protein
COKMIKJD_01875 7.6e-91 MA20_25245 K FR47-like protein
COKMIKJD_01876 4.5e-140 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
COKMIKJD_01877 4.8e-287 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COKMIKJD_01878 1.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COKMIKJD_01879 1.4e-72
COKMIKJD_01880 0.0 yhgF K Tex-like protein N-terminal domain protein
COKMIKJD_01881 4e-89 ydcK S Belongs to the SprT family
COKMIKJD_01882 3.7e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COKMIKJD_01884 5.5e-151 4.1.1.52 S Amidohydrolase
COKMIKJD_01885 2.5e-123 S Alpha/beta hydrolase family
COKMIKJD_01886 1.5e-60 yobS K transcriptional regulator
COKMIKJD_01887 1.8e-115 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
COKMIKJD_01888 2.6e-98 S Psort location CytoplasmicMembrane, score
COKMIKJD_01889 1.5e-74 K MarR family
COKMIKJD_01890 3e-246 dinF V MatE
COKMIKJD_01891 8.3e-108 gph 3.1.3.18 S HAD hydrolase, family IA, variant
COKMIKJD_01892 4.3e-55 manL 2.7.1.191 G PTS system fructose IIA component
COKMIKJD_01893 1.4e-60 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
COKMIKJD_01894 2.5e-117 manM G PTS system
COKMIKJD_01895 2.5e-155 manN G system, mannose fructose sorbose family IID component
COKMIKJD_01896 2.9e-177 K AI-2E family transporter
COKMIKJD_01897 3.8e-167 2.7.7.65 T diguanylate cyclase
COKMIKJD_01898 5.5e-118 yliE T EAL domain
COKMIKJD_01899 2.8e-102 K Bacterial regulatory proteins, tetR family
COKMIKJD_01900 2.3e-197 XK27_06930 V domain protein
COKMIKJD_01901 2.2e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
COKMIKJD_01902 4.2e-198 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COKMIKJD_01903 7.9e-166 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
COKMIKJD_01904 4.7e-172 EG EamA-like transporter family
COKMIKJD_01905 7.7e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COKMIKJD_01906 7.8e-230 V Beta-lactamase
COKMIKJD_01907 5e-259 pepC 3.4.22.40 E Peptidase C1-like family
COKMIKJD_01908 5.3e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COKMIKJD_01909 2e-55
COKMIKJD_01910 1.3e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
COKMIKJD_01911 1.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COKMIKJD_01912 1.1e-212 yacL S domain protein
COKMIKJD_01913 6.8e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COKMIKJD_01914 7.4e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
COKMIKJD_01915 7.8e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COKMIKJD_01916 2.5e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COKMIKJD_01917 1.8e-90 yacP S YacP-like NYN domain
COKMIKJD_01918 1.5e-98 sigH K Sigma-70 region 2
COKMIKJD_01919 3.3e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COKMIKJD_01920 1.1e-98 nusG K Participates in transcription elongation, termination and antitermination
COKMIKJD_01921 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COKMIKJD_01922 1.2e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COKMIKJD_01923 6.9e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COKMIKJD_01924 4e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COKMIKJD_01925 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COKMIKJD_01926 2.4e-109 yvdD 3.2.2.10 S Belongs to the LOG family
COKMIKJD_01927 1.7e-111 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
COKMIKJD_01928 5e-44 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
COKMIKJD_01929 1.9e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COKMIKJD_01930 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COKMIKJD_01931 6.4e-37 nrdH O Glutaredoxin
COKMIKJD_01932 1.2e-109 rsmC 2.1.1.172 J Methyltransferase
COKMIKJD_01933 1.3e-88 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COKMIKJD_01934 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COKMIKJD_01935 3.6e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COKMIKJD_01936 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COKMIKJD_01937 3.7e-38 yaaL S Protein of unknown function (DUF2508)
COKMIKJD_01938 6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COKMIKJD_01939 2.2e-54 yaaQ S Cyclic-di-AMP receptor
COKMIKJD_01940 1.5e-178 holB 2.7.7.7 L DNA polymerase III
COKMIKJD_01941 3.3e-37 yabA L Involved in initiation control of chromosome replication
COKMIKJD_01942 4.9e-162 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COKMIKJD_01943 5.8e-140 fat 3.1.2.21 I Acyl-ACP thioesterase
COKMIKJD_01944 4e-125 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
COKMIKJD_01945 2.6e-109 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
COKMIKJD_01946 1.4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COKMIKJD_01947 1.7e-213 yeaN P Transporter, major facilitator family protein
COKMIKJD_01948 7.5e-46 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
COKMIKJD_01949 0.0 uup S ABC transporter, ATP-binding protein
COKMIKJD_01950 2e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COKMIKJD_01951 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COKMIKJD_01952 4.2e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COKMIKJD_01953 0.0 ydaO E amino acid
COKMIKJD_01954 3.7e-140 lrgB M LrgB-like family
COKMIKJD_01955 1.6e-60 lrgA S LrgA family
COKMIKJD_01956 3.6e-178 tagO 2.7.8.33, 2.7.8.35 M transferase
COKMIKJD_01957 3.5e-112 yvyE 3.4.13.9 S YigZ family
COKMIKJD_01958 7.7e-252 comFA L Helicase C-terminal domain protein
COKMIKJD_01959 4.8e-117 comFC S Competence protein
COKMIKJD_01960 7.9e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COKMIKJD_01961 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COKMIKJD_01962 8e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COKMIKJD_01963 1.8e-212 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
COKMIKJD_01964 2e-129 K response regulator
COKMIKJD_01965 3.2e-245 phoR 2.7.13.3 T Histidine kinase
COKMIKJD_01966 6.7e-159 pstS P Phosphate
COKMIKJD_01967 2.3e-157 pstC P probably responsible for the translocation of the substrate across the membrane
COKMIKJD_01968 1e-154 pstA P Phosphate transport system permease protein PstA
COKMIKJD_01969 1.8e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COKMIKJD_01970 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COKMIKJD_01971 6.8e-119 phoU P Plays a role in the regulation of phosphate uptake
COKMIKJD_01972 1.7e-54 pspC KT PspC domain protein
COKMIKJD_01973 1.2e-29 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
COKMIKJD_01974 1.4e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COKMIKJD_01975 8e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COKMIKJD_01976 3.4e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
COKMIKJD_01977 5.8e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COKMIKJD_01978 4.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COKMIKJD_01980 6.7e-116 yfbR S HD containing hydrolase-like enzyme
COKMIKJD_01981 6.5e-93 K acetyltransferase
COKMIKJD_01982 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COKMIKJD_01983 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COKMIKJD_01984 2.4e-90 S Short repeat of unknown function (DUF308)
COKMIKJD_01985 4.8e-165 rapZ S Displays ATPase and GTPase activities
COKMIKJD_01986 4.5e-191 ybhK S Required for morphogenesis under gluconeogenic growth conditions
COKMIKJD_01987 9.9e-169 whiA K May be required for sporulation
COKMIKJD_01988 1.7e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COKMIKJD_01989 2.2e-73 XK27_02470 K LytTr DNA-binding domain
COKMIKJD_01990 1.3e-120 liaI S membrane
COKMIKJD_01992 2.4e-107 S ECF transporter, substrate-specific component
COKMIKJD_01994 3.1e-184 cggR K Putative sugar-binding domain
COKMIKJD_01995 9e-192 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COKMIKJD_01996 4.3e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
COKMIKJD_01997 2.5e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COKMIKJD_01998 8e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COKMIKJD_02000 6.5e-282 clcA P chloride
COKMIKJD_02001 4.9e-32 secG U Preprotein translocase
COKMIKJD_02002 1.6e-137 est 3.1.1.1 S Serine aminopeptidase, S33
COKMIKJD_02003 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COKMIKJD_02004 2.3e-81 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COKMIKJD_02005 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COKMIKJD_02006 1.4e-98 yxjI
COKMIKJD_02007 3e-141 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COKMIKJD_02008 1.6e-177 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
COKMIKJD_02009 1.9e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
COKMIKJD_02010 1.9e-84 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
COKMIKJD_02011 4.8e-193 C Aldo keto reductase family protein
COKMIKJD_02012 5.1e-101 dnaQ 2.7.7.7 L DNA polymerase III
COKMIKJD_02013 9e-152 xth 3.1.11.2 L exodeoxyribonuclease III
COKMIKJD_02014 5e-165 murB 1.3.1.98 M Cell wall formation
COKMIKJD_02015 0.0 yjcE P Sodium proton antiporter
COKMIKJD_02016 1.2e-123 S Protein of unknown function (DUF1361)
COKMIKJD_02017 4.5e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COKMIKJD_02018 4.3e-135 ybbR S YbbR-like protein
COKMIKJD_02019 7.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COKMIKJD_02020 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COKMIKJD_02021 1.7e-12
COKMIKJD_02022 5.9e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COKMIKJD_02023 6e-250 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COKMIKJD_02024 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
COKMIKJD_02025 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
COKMIKJD_02026 1.2e-92 dps P Belongs to the Dps family
COKMIKJD_02027 1.5e-25 copZ P Heavy-metal-associated domain
COKMIKJD_02028 6.2e-199 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
COKMIKJD_02029 1.8e-50
COKMIKJD_02030 4.2e-82 S Iron Transport-associated domain
COKMIKJD_02031 2.8e-176 M Iron Transport-associated domain
COKMIKJD_02032 1.7e-86 M Iron Transport-associated domain
COKMIKJD_02033 6.6e-162 isdE P Periplasmic binding protein
COKMIKJD_02034 6.4e-171 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COKMIKJD_02035 2.7e-140 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
COKMIKJD_02036 2.6e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COKMIKJD_02037 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COKMIKJD_02038 9.2e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COKMIKJD_02039 3.7e-151 licD M LicD family
COKMIKJD_02040 1.5e-74 S Domain of unknown function (DUF5067)
COKMIKJD_02041 3.3e-74 K Transcriptional regulator
COKMIKJD_02042 1.9e-25
COKMIKJD_02043 2.7e-79 O OsmC-like protein
COKMIKJD_02044 3.2e-23
COKMIKJD_02046 5.9e-56 ypaA S Protein of unknown function (DUF1304)
COKMIKJD_02047 1.5e-86
COKMIKJD_02048 3.6e-252 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COKMIKJD_02049 9.3e-46 sigM K Sigma-70 region 2
COKMIKJD_02050 2.5e-71 S Sigma factor regulator C-terminal
COKMIKJD_02051 3.1e-202 E Bacterial extracellular solute-binding proteins, family 5 Middle
COKMIKJD_02052 3.7e-249 dapE 3.5.1.18 E Peptidase dimerisation domain
COKMIKJD_02053 1.5e-67 L Putative transposase of IS4/5 family (DUF4096)
COKMIKJD_02054 3.7e-210 G MFS/sugar transport protein
COKMIKJD_02055 2.5e-119 K AraC family transcriptional regulator
COKMIKJD_02056 0.0 rafA 3.2.1.22 G Melibiase
COKMIKJD_02057 6.8e-105
COKMIKJD_02058 3.5e-16
COKMIKJD_02061 9e-147 K response regulator
COKMIKJD_02062 4.2e-267 T PhoQ Sensor
COKMIKJD_02063 1.1e-209 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
COKMIKJD_02064 2.9e-154 glcU U sugar transport
COKMIKJD_02065 7.1e-261 pgi 5.3.1.9 G Belongs to the GPI family
COKMIKJD_02066 0.0 S Bacterial membrane protein YfhO
COKMIKJD_02067 2.2e-79 tspO T TspO/MBR family
COKMIKJD_02070 9e-204 sip L Belongs to the 'phage' integrase family
COKMIKJD_02071 3.5e-13 K Helix-turn-helix XRE-family like proteins
COKMIKJD_02075 4e-07
COKMIKJD_02076 1e-105 L Bifunctional DNA primase/polymerase, N-terminal
COKMIKJD_02077 1.1e-243 S Virulence-associated protein E
COKMIKJD_02078 2.5e-58
COKMIKJD_02080 9e-19 S head-tail joining protein
COKMIKJD_02081 2.1e-56 L HNH endonuclease
COKMIKJD_02082 6.5e-76 terS L overlaps another CDS with the same product name
COKMIKJD_02083 1.4e-309 terL S overlaps another CDS with the same product name
COKMIKJD_02085 1.2e-194 S Phage portal protein
COKMIKJD_02086 2.9e-266 S Caudovirus prohead serine protease
COKMIKJD_02087 1e-36 ypaA S Protein of unknown function (DUF1304)
COKMIKJD_02088 5.6e-32 S Phage gp6-like head-tail connector protein
COKMIKJD_02089 7.7e-40
COKMIKJD_02091 2.5e-159 S NAD:arginine ADP-ribosyltransferase
COKMIKJD_02092 5.4e-198 ybiR P Citrate transporter
COKMIKJD_02093 2.1e-120 yliE T Putative diguanylate phosphodiesterase
COKMIKJD_02094 1.1e-145 2.7.7.65 T diguanylate cyclase
COKMIKJD_02095 1.1e-08
COKMIKJD_02096 8.9e-56
COKMIKJD_02097 0.0 lmrA V ABC transporter, ATP-binding protein
COKMIKJD_02098 0.0 yfiC V ABC transporter
COKMIKJD_02099 4.1e-192 ampC V Beta-lactamase
COKMIKJD_02100 4.3e-132 cobQ S glutamine amidotransferase
COKMIKJD_02101 1.2e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
COKMIKJD_02102 8.5e-110 tdk 2.7.1.21 F thymidine kinase
COKMIKJD_02103 3.5e-186 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COKMIKJD_02104 1.8e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COKMIKJD_02105 2.7e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COKMIKJD_02106 3.9e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COKMIKJD_02107 1.5e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COKMIKJD_02108 6.1e-126 atpB C it plays a direct role in the translocation of protons across the membrane
COKMIKJD_02109 7.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COKMIKJD_02110 3.4e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COKMIKJD_02111 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COKMIKJD_02112 1.6e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COKMIKJD_02113 3.6e-160 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COKMIKJD_02114 5.3e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COKMIKJD_02115 1.1e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COKMIKJD_02116 1.3e-32 ywzB S Protein of unknown function (DUF1146)
COKMIKJD_02117 9.4e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COKMIKJD_02118 6e-180 mbl D Cell shape determining protein MreB Mrl
COKMIKJD_02119 1.1e-52 yidD S Could be involved in insertion of integral membrane proteins into the membrane
COKMIKJD_02120 1.1e-33 S Protein of unknown function (DUF2969)
COKMIKJD_02121 1.1e-220 rodA D Belongs to the SEDS family
COKMIKJD_02122 1.9e-49 gcsH2 E glycine cleavage
COKMIKJD_02123 1.3e-140 f42a O Band 7 protein
COKMIKJD_02124 3.9e-176 S Protein of unknown function (DUF2785)
COKMIKJD_02125 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COKMIKJD_02126 9.3e-289 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
COKMIKJD_02127 2.2e-157 2.3.1.19 K Helix-turn-helix XRE-family like proteins
COKMIKJD_02128 1e-81 usp6 T universal stress protein
COKMIKJD_02129 3.2e-41
COKMIKJD_02130 9.8e-236 rarA L recombination factor protein RarA
COKMIKJD_02131 4.2e-80 yueI S Protein of unknown function (DUF1694)
COKMIKJD_02132 7.9e-111 yktB S Belongs to the UPF0637 family
COKMIKJD_02133 7.1e-61 KLT serine threonine protein kinase
COKMIKJD_02134 4.8e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COKMIKJD_02135 9.2e-83 ytsP 1.8.4.14 T GAF domain-containing protein
COKMIKJD_02136 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COKMIKJD_02137 7.2e-214 iscS2 2.8.1.7 E Aminotransferase class V
COKMIKJD_02138 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COKMIKJD_02139 3.5e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COKMIKJD_02140 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COKMIKJD_02141 1e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COKMIKJD_02142 5.6e-118 radC L DNA repair protein
COKMIKJD_02143 9.6e-162 mreB D cell shape determining protein MreB
COKMIKJD_02144 9.7e-139 mreC M Involved in formation and maintenance of cell shape
COKMIKJD_02145 3.2e-92 mreD M rod shape-determining protein MreD
COKMIKJD_02146 1.8e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
COKMIKJD_02147 4.1e-147 minD D Belongs to the ParA family
COKMIKJD_02148 2.5e-110 glnP P ABC transporter permease
COKMIKJD_02149 1.6e-93 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COKMIKJD_02150 7.8e-157 aatB ET ABC transporter substrate-binding protein
COKMIKJD_02151 1.4e-234 ymfF S Peptidase M16 inactive domain protein
COKMIKJD_02152 2.3e-245 ymfH S Peptidase M16
COKMIKJD_02153 1.8e-74 ymfM S Domain of unknown function (DUF4115)
COKMIKJD_02154 1e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COKMIKJD_02155 4.9e-224 cinA 3.5.1.42 S Belongs to the CinA family
COKMIKJD_02156 1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COKMIKJD_02158 8.9e-223 rny S Endoribonuclease that initiates mRNA decay
COKMIKJD_02159 5.1e-150 ymdB S YmdB-like protein
COKMIKJD_02160 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COKMIKJD_02161 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COKMIKJD_02162 1.4e-107 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COKMIKJD_02163 1.2e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COKMIKJD_02164 1.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
COKMIKJD_02165 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COKMIKJD_02166 1.1e-26 yajC U Preprotein translocase
COKMIKJD_02167 3.5e-181 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COKMIKJD_02168 9e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
COKMIKJD_02169 1.4e-251 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COKMIKJD_02170 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COKMIKJD_02171 1.9e-43 yrzL S Belongs to the UPF0297 family
COKMIKJD_02172 1.5e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COKMIKJD_02173 1.6e-51 yrzB S Belongs to the UPF0473 family
COKMIKJD_02174 1.4e-38 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
COKMIKJD_02175 6.4e-88 cvpA S Colicin V production protein
COKMIKJD_02176 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COKMIKJD_02177 2.7e-54 trxA O Belongs to the thioredoxin family
COKMIKJD_02178 7.2e-92 yslB S Protein of unknown function (DUF2507)
COKMIKJD_02179 1.8e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COKMIKJD_02180 6.2e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COKMIKJD_02181 1.9e-100 S Phosphoesterase
COKMIKJD_02182 4.6e-85 ykuL S (CBS) domain
COKMIKJD_02184 1.5e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
COKMIKJD_02185 6.8e-243 U Major Facilitator Superfamily
COKMIKJD_02186 4.1e-156 ykuT M mechanosensitive ion channel
COKMIKJD_02187 6.9e-34 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COKMIKJD_02188 9.5e-43
COKMIKJD_02189 2.7e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COKMIKJD_02190 4.6e-180 ccpA K catabolite control protein A
COKMIKJD_02191 1.1e-126
COKMIKJD_02192 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COKMIKJD_02193 2.1e-266 glnPH2 P ABC transporter permease
COKMIKJD_02194 2.6e-132 yebC K Transcriptional regulatory protein
COKMIKJD_02195 3e-131 comGA NU Type II IV secretion system protein
COKMIKJD_02196 2.9e-169 comGB NU type II secretion system
COKMIKJD_02197 1.2e-46 comGC U competence protein ComGC
COKMIKJD_02198 9.2e-80
COKMIKJD_02200 7.1e-74
COKMIKJD_02201 7.4e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
COKMIKJD_02202 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COKMIKJD_02203 6.1e-255 cycA E Amino acid permease
COKMIKJD_02204 2.5e-155 yeaE S Aldo keto
COKMIKJD_02205 1.2e-114 S Calcineurin-like phosphoesterase
COKMIKJD_02206 5.6e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
COKMIKJD_02207 2.9e-82 yutD S Protein of unknown function (DUF1027)
COKMIKJD_02208 6.5e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COKMIKJD_02209 3.8e-116 S Protein of unknown function (DUF1461)
COKMIKJD_02210 4.5e-88 S WxL domain surface cell wall-binding
COKMIKJD_02211 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
COKMIKJD_02212 4.6e-234 M domain protein
COKMIKJD_02213 1.2e-250 yfnA E Amino Acid
COKMIKJD_02214 7.4e-141 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
COKMIKJD_02215 4.5e-112 ytbE C Aldo keto reductase
COKMIKJD_02216 7.9e-64 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COKMIKJD_02217 3.4e-13 K helix_turn_helix, mercury resistance
COKMIKJD_02218 2.9e-122 dedA S SNARE-like domain protein
COKMIKJD_02219 6.1e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
COKMIKJD_02220 1.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COKMIKJD_02221 5.2e-71 yugI 5.3.1.9 J general stress protein
COKMIKJD_02222 1.3e-28
COKMIKJD_02223 2.6e-116 mltD CBM50 M NlpC P60 family protein
COKMIKJD_02224 9.7e-165 ypuA S Protein of unknown function (DUF1002)
COKMIKJD_02225 4.2e-169 ykfC 3.4.14.13 M NlpC/P60 family
COKMIKJD_02226 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
COKMIKJD_02227 2.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COKMIKJD_02228 1.2e-183 rbsR K helix_turn _helix lactose operon repressor
COKMIKJD_02229 3.5e-188 yghZ C Aldo keto reductase family protein
COKMIKJD_02230 2.6e-158 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
COKMIKJD_02231 2.5e-308 E ABC transporter, substratebinding protein
COKMIKJD_02232 1.1e-275 nylA 3.5.1.4 J Belongs to the amidase family
COKMIKJD_02233 4.3e-158 yckB ET Belongs to the bacterial solute-binding protein 3 family
COKMIKJD_02234 2.5e-121 yecS E ABC transporter permease
COKMIKJD_02235 1.2e-126 yoaK S Protein of unknown function (DUF1275)
COKMIKJD_02236 1.4e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COKMIKJD_02237 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COKMIKJD_02238 6.8e-119 S Repeat protein
COKMIKJD_02239 5e-119 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
COKMIKJD_02240 2.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COKMIKJD_02242 1.5e-58 XK27_04120 S Putative amino acid metabolism
COKMIKJD_02243 4e-223 iscS 2.8.1.7 E Aminotransferase class V
COKMIKJD_02244 2.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COKMIKJD_02245 3.4e-30
COKMIKJD_02246 2.5e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
COKMIKJD_02247 2.2e-34 cspA K Cold shock protein
COKMIKJD_02248 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COKMIKJD_02249 3.3e-92 divIVA D DivIVA domain protein
COKMIKJD_02250 1.5e-146 ylmH S S4 domain protein
COKMIKJD_02251 5.3e-41 yggT S YGGT family
COKMIKJD_02252 1.5e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COKMIKJD_02253 1.1e-215 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COKMIKJD_02254 1e-243 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COKMIKJD_02255 4e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COKMIKJD_02256 3.1e-198 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COKMIKJD_02257 1.1e-248 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COKMIKJD_02258 4.3e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COKMIKJD_02259 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
COKMIKJD_02260 1.7e-61 ftsL D Cell division protein FtsL
COKMIKJD_02261 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COKMIKJD_02262 2e-79 mraZ K Belongs to the MraZ family
COKMIKJD_02263 4.9e-60 S Protein of unknown function (DUF3397)
COKMIKJD_02264 2.2e-12 S Protein of unknown function (DUF4044)
COKMIKJD_02265 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
COKMIKJD_02266 2.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COKMIKJD_02267 2.2e-159 rrmA 2.1.1.187 H Methyltransferase
COKMIKJD_02268 1.3e-202 XK27_05220 S AI-2E family transporter
COKMIKJD_02269 1.5e-107 cutC P Participates in the control of copper homeostasis
COKMIKJD_02271 2.2e-58 N Cell shape-determining protein MreB
COKMIKJD_02272 1e-242 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
COKMIKJD_02273 2e-187 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
COKMIKJD_02274 3.2e-153 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
COKMIKJD_02275 1.5e-40 vat S acetyltransferase, isoleucine patch superfamily
COKMIKJD_02276 7e-81 vat S acetyltransferase, isoleucine patch superfamily
COKMIKJD_02278 5.4e-164 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
COKMIKJD_02280 6.1e-160 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
COKMIKJD_02281 1.3e-154 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
COKMIKJD_02282 1.1e-33 N Cell shape-determining protein MreB
COKMIKJD_02283 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
COKMIKJD_02284 6.8e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COKMIKJD_02285 3.3e-118 yjbM 2.7.6.5 S RelA SpoT domain protein
COKMIKJD_02286 9.9e-112 yjbH Q Thioredoxin
COKMIKJD_02287 2.5e-158 degV S DegV family
COKMIKJD_02288 0.0 pepF E oligoendopeptidase F
COKMIKJD_02289 1.5e-187 coiA 3.6.4.12 S Competence protein
COKMIKJD_02290 2.3e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COKMIKJD_02291 4.3e-149 ytmP 2.7.1.89 M Choline/ethanolamine kinase
COKMIKJD_02292 1.3e-216 ecsB U ABC transporter
COKMIKJD_02293 6.2e-134 ecsA V ABC transporter, ATP-binding protein
COKMIKJD_02294 3.1e-83 hit FG histidine triad
COKMIKJD_02295 2.8e-46
COKMIKJD_02296 9.1e-151 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COKMIKJD_02297 3.9e-184 S Metal dependent phosphohydrolases with conserved 'HD' motif.
COKMIKJD_02298 0.0 L AAA domain
COKMIKJD_02299 2.2e-229 yhaO L Ser Thr phosphatase family protein
COKMIKJD_02300 4.8e-52 yheA S Belongs to the UPF0342 family
COKMIKJD_02301 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COKMIKJD_02302 4.7e-79 argR K Regulates arginine biosynthesis genes
COKMIKJD_02303 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
COKMIKJD_02305 1.1e-17
COKMIKJD_02306 5.5e-231 3.2.1.96, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
COKMIKJD_02307 3.7e-96 1.5.1.3 H RibD C-terminal domain
COKMIKJD_02308 8.6e-54 S Protein of unknown function (DUF1516)
COKMIKJD_02309 1.8e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
COKMIKJD_02310 4.8e-251 yxbA 6.3.1.12 S ATP-grasp enzyme
COKMIKJD_02311 0.0 asnB 6.3.5.4 E Asparagine synthase
COKMIKJD_02312 1.1e-119 ntcA2 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
COKMIKJD_02313 2.5e-269 pipD E Peptidase family C69
COKMIKJD_02314 1.3e-37
COKMIKJD_02315 0.0
COKMIKJD_02318 0.0 uvrA3 L ABC transporter
COKMIKJD_02320 5.1e-47
COKMIKJD_02321 2.1e-83 V VanZ like family
COKMIKJD_02322 9.4e-83 ohrR K Transcriptional regulator
COKMIKJD_02323 7.3e-121 S CAAX protease self-immunity
COKMIKJD_02324 2.9e-35
COKMIKJD_02325 4.3e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COKMIKJD_02326 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
COKMIKJD_02327 2.4e-108 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
COKMIKJD_02328 2.9e-142 S haloacid dehalogenase-like hydrolase
COKMIKJD_02329 4.5e-120 dck 2.7.1.74 F Deoxynucleoside kinase
COKMIKJD_02330 1.8e-56 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
COKMIKJD_02331 1.2e-253 bmr3 EGP Major facilitator Superfamily
COKMIKJD_02332 3.7e-213 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COKMIKJD_02333 3.7e-107
COKMIKJD_02334 3e-46
COKMIKJD_02335 5.4e-93
COKMIKJD_02336 1.7e-51 ybjQ S Belongs to the UPF0145 family
COKMIKJD_02337 1.6e-83 zmp2 O Zinc-dependent metalloprotease
COKMIKJD_02351 6.8e-95 I NUDIX domain
COKMIKJD_02352 1.1e-113 yviA S Protein of unknown function (DUF421)
COKMIKJD_02353 1.3e-73 S Protein of unknown function (DUF3290)
COKMIKJD_02354 8.5e-162 ropB K Helix-turn-helix XRE-family like proteins
COKMIKJD_02355 4.4e-204 EGP Major facilitator Superfamily
COKMIKJD_02356 4e-248 gshR 1.8.1.7 C Glutathione reductase
COKMIKJD_02357 9.1e-36 ygbF S Sugar efflux transporter for intercellular exchange
COKMIKJD_02359 2.7e-187 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COKMIKJD_02360 1e-35
COKMIKJD_02361 6.3e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
COKMIKJD_02362 9e-232 gntT EG Citrate transporter
COKMIKJD_02363 2e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
COKMIKJD_02364 2.1e-106 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase HUMPS family
COKMIKJD_02365 3.2e-87 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M sugar phosphate isomerase involved in capsule formation
COKMIKJD_02366 5.2e-176 kdgR K helix_turn _helix lactose operon repressor
COKMIKJD_02367 6.2e-54
COKMIKJD_02368 1.8e-83
COKMIKJD_02369 0.0 helD 3.6.4.12 L DNA helicase
COKMIKJD_02371 1.2e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
COKMIKJD_02372 5.7e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COKMIKJD_02373 1.2e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
COKMIKJD_02374 5.4e-178
COKMIKJD_02375 1.2e-129 cobB K SIR2 family
COKMIKJD_02376 9.4e-50
COKMIKJD_02377 4e-161 yunF F Protein of unknown function DUF72
COKMIKJD_02378 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COKMIKJD_02379 1.5e-146 tatD L hydrolase, TatD family
COKMIKJD_02380 4.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COKMIKJD_02381 8.5e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COKMIKJD_02382 4.3e-36 veg S Biofilm formation stimulator VEG
COKMIKJD_02383 1.9e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COKMIKJD_02384 3.2e-109 ung2 3.2.2.27 L Uracil-DNA glycosylase
COKMIKJD_02385 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
COKMIKJD_02386 2.8e-260 xylP G MFS/sugar transport protein
COKMIKJD_02387 1.9e-209 xylR GK ROK family
COKMIKJD_02388 9.1e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COKMIKJD_02389 1.7e-160 2.7.1.2 GK ROK family
COKMIKJD_02390 1.7e-87
COKMIKJD_02392 4.5e-55 V Transport permease protein
COKMIKJD_02393 7.8e-88 V ABC transporter
COKMIKJD_02394 8.4e-86 KTV abc transporter atp-binding protein
COKMIKJD_02395 2.4e-157 S Prolyl oligopeptidase family
COKMIKJD_02396 6.8e-170 znuA P Belongs to the bacterial solute-binding protein 9 family
COKMIKJD_02397 3.6e-131 fhuC P ABC transporter
COKMIKJD_02398 1.4e-131 znuB U ABC 3 transport family
COKMIKJD_02401 1.5e-144 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
COKMIKJD_02402 2.5e-216 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COKMIKJD_02403 5.5e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COKMIKJD_02404 9.7e-56 S Domain of unknown function (DUF3899)
COKMIKJD_02405 2e-68 racA K helix_turn_helix, mercury resistance
COKMIKJD_02406 1.1e-130 gntR K UbiC transcription regulator-associated domain protein
COKMIKJD_02407 0.0 xpkA 4.1.2.22, 4.1.2.9 G Phosphoketolase
COKMIKJD_02408 1.3e-143 yxeH S hydrolase
COKMIKJD_02409 1.3e-265 ywfO S HD domain protein
COKMIKJD_02410 2.7e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
COKMIKJD_02411 2.2e-78 ywiB S Domain of unknown function (DUF1934)
COKMIKJD_02412 5.8e-54 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COKMIKJD_02413 1.7e-309 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COKMIKJD_02414 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
COKMIKJD_02415 2.1e-201
COKMIKJD_02416 3.9e-72 K Transcriptional regulator
COKMIKJD_02417 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
COKMIKJD_02418 1.7e-128 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
COKMIKJD_02419 6.8e-165 pelX UW LPXTG-motif cell wall anchor domain protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)