ORF_ID e_value Gene_name EC_number CAZy COGs Description
LEOAPNPK_00001 0.0 4.2.1.53 S Myosin-crossreactive antigen
LEOAPNPK_00002 2e-91 yxdD K Bacterial regulatory proteins, tetR family
LEOAPNPK_00003 1.7e-260 emrY EGP Major facilitator Superfamily
LEOAPNPK_00008 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
LEOAPNPK_00009 2.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEOAPNPK_00010 9.2e-200 pbpX V Beta-lactamase
LEOAPNPK_00011 2.8e-244 nhaC C Na H antiporter NhaC
LEOAPNPK_00012 1.8e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
LEOAPNPK_00013 2.6e-57
LEOAPNPK_00014 4.3e-108 ybhL S Belongs to the BI1 family
LEOAPNPK_00015 7.2e-172 yegS 2.7.1.107 G Lipid kinase
LEOAPNPK_00016 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEOAPNPK_00017 5.2e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEOAPNPK_00018 5.8e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEOAPNPK_00019 5.4e-201 camS S sex pheromone
LEOAPNPK_00020 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEOAPNPK_00021 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LEOAPNPK_00022 2.5e-86 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
LEOAPNPK_00024 2.8e-84 ydcK S Belongs to the SprT family
LEOAPNPK_00025 9.1e-135 M Glycosyltransferase sugar-binding region containing DXD motif
LEOAPNPK_00026 6.4e-260 epsU S Polysaccharide biosynthesis protein
LEOAPNPK_00027 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LEOAPNPK_00028 0.0 pacL 3.6.3.8 P P-type ATPase
LEOAPNPK_00029 4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEOAPNPK_00030 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEOAPNPK_00031 9e-206 csaB M Glycosyl transferases group 1
LEOAPNPK_00032 4.3e-135 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LEOAPNPK_00033 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
LEOAPNPK_00034 4.6e-123 gntR1 K UTRA
LEOAPNPK_00035 1.1e-179
LEOAPNPK_00036 5.5e-300 oppA2 E ABC transporter, substratebinding protein
LEOAPNPK_00039 1.1e-240 npr 1.11.1.1 C NADH oxidase
LEOAPNPK_00040 7.7e-12
LEOAPNPK_00041 1.3e-22 3.6.4.12 S transposase or invertase
LEOAPNPK_00042 4.9e-87 S SLAP domain
LEOAPNPK_00043 2.9e-143 K SIS domain
LEOAPNPK_00044 2.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
LEOAPNPK_00045 2.1e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
LEOAPNPK_00046 7.7e-219 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
LEOAPNPK_00048 2.8e-112 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEOAPNPK_00049 3.1e-116 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
LEOAPNPK_00050 5.4e-87 G Histidine phosphatase superfamily (branch 1)
LEOAPNPK_00051 1.2e-105 G Phosphoglycerate mutase family
LEOAPNPK_00052 1.5e-160 D nuclear chromosome segregation
LEOAPNPK_00053 6.8e-79 M LysM domain protein
LEOAPNPK_00054 1.1e-28 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEOAPNPK_00055 1.1e-115 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEOAPNPK_00056 3.6e-254 L Putative transposase DNA-binding domain
LEOAPNPK_00057 4.1e-118 L Resolvase, N-terminal
LEOAPNPK_00058 6.2e-12
LEOAPNPK_00059 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
LEOAPNPK_00060 4.6e-31
LEOAPNPK_00061 1.1e-179 L COG2963 Transposase and inactivated derivatives
LEOAPNPK_00063 1.5e-70 S Iron-sulphur cluster biosynthesis
LEOAPNPK_00064 3.8e-113 yncA 2.3.1.79 S Maltose acetyltransferase
LEOAPNPK_00065 1e-61 psiE S Phosphate-starvation-inducible E
LEOAPNPK_00067 8.4e-142 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LEOAPNPK_00068 1.9e-59
LEOAPNPK_00069 0.0 lhr L DEAD DEAH box helicase
LEOAPNPK_00070 5.4e-253 P P-loop Domain of unknown function (DUF2791)
LEOAPNPK_00071 0.0 S TerB-C domain
LEOAPNPK_00072 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
LEOAPNPK_00073 3.9e-298 V ABC transporter transmembrane region
LEOAPNPK_00075 6.7e-156 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_00076 7.2e-71 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
LEOAPNPK_00077 4.7e-32
LEOAPNPK_00078 2.3e-169 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEOAPNPK_00079 1.6e-07 ackA 2.7.2.1 F acetate kinase activity
LEOAPNPK_00080 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEOAPNPK_00081 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LEOAPNPK_00082 1.6e-244 cycA E Amino acid permease
LEOAPNPK_00083 6.9e-87 maa S transferase hexapeptide repeat
LEOAPNPK_00084 8.7e-159 K Transcriptional regulator
LEOAPNPK_00085 9.9e-64 manO S Domain of unknown function (DUF956)
LEOAPNPK_00086 1e-173 manN G system, mannose fructose sorbose family IID component
LEOAPNPK_00087 1.7e-129 manY G PTS system
LEOAPNPK_00088 8.7e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
LEOAPNPK_00089 3.8e-196 pbpX1 V Beta-lactamase
LEOAPNPK_00090 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEOAPNPK_00091 1.4e-217 aspC 2.6.1.1 E Aminotransferase
LEOAPNPK_00092 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEOAPNPK_00093 4.4e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEOAPNPK_00094 1.1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEOAPNPK_00095 9.7e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEOAPNPK_00096 5.1e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEOAPNPK_00097 6.7e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
LEOAPNPK_00098 1.5e-191 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEOAPNPK_00099 2.7e-103 yjeM E Amino acid permease
LEOAPNPK_00100 1.3e-22 yjeM E Amino Acid
LEOAPNPK_00101 3.7e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
LEOAPNPK_00102 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEOAPNPK_00103 4e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEOAPNPK_00104 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEOAPNPK_00105 8.3e-151
LEOAPNPK_00106 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEOAPNPK_00107 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEOAPNPK_00108 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
LEOAPNPK_00109 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
LEOAPNPK_00110 0.0 comEC S Competence protein ComEC
LEOAPNPK_00111 6.5e-77 comEA L Competence protein ComEA
LEOAPNPK_00112 3.3e-189 ylbL T Belongs to the peptidase S16 family
LEOAPNPK_00113 1.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEOAPNPK_00114 1.7e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
LEOAPNPK_00115 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
LEOAPNPK_00116 2.7e-211 ftsW D Belongs to the SEDS family
LEOAPNPK_00117 0.0 typA T GTP-binding protein TypA
LEOAPNPK_00118 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEOAPNPK_00119 3.2e-33 ykzG S Belongs to the UPF0356 family
LEOAPNPK_00120 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEOAPNPK_00121 1.8e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LEOAPNPK_00122 7e-295 L Nuclease-related domain
LEOAPNPK_00123 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEOAPNPK_00124 5.4e-105 S Repeat protein
LEOAPNPK_00125 1.5e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
LEOAPNPK_00126 4.6e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEOAPNPK_00127 2.2e-57 XK27_04120 S Putative amino acid metabolism
LEOAPNPK_00128 2.7e-216 iscS 2.8.1.7 E Aminotransferase class V
LEOAPNPK_00129 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEOAPNPK_00130 2.1e-38
LEOAPNPK_00131 9.8e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
LEOAPNPK_00132 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
LEOAPNPK_00133 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEOAPNPK_00134 2.8e-74 gpsB D DivIVA domain protein
LEOAPNPK_00135 7.4e-149 ylmH S S4 domain protein
LEOAPNPK_00136 1.7e-45 yggT S YGGT family
LEOAPNPK_00137 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEOAPNPK_00138 5.5e-205 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEOAPNPK_00139 1.3e-243 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEOAPNPK_00140 1.2e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEOAPNPK_00141 4.4e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEOAPNPK_00142 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEOAPNPK_00143 1.1e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEOAPNPK_00144 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LEOAPNPK_00145 4.1e-54 ftsL D Cell division protein FtsL
LEOAPNPK_00146 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEOAPNPK_00147 6.3e-78 mraZ K Belongs to the MraZ family
LEOAPNPK_00148 6.4e-54 S Protein of unknown function (DUF3397)
LEOAPNPK_00150 1.2e-94 mreD
LEOAPNPK_00151 6.7e-148 mreC M Involved in formation and maintenance of cell shape
LEOAPNPK_00152 1.8e-176 mreB D cell shape determining protein MreB
LEOAPNPK_00153 2.3e-108 radC L DNA repair protein
LEOAPNPK_00154 7.5e-126 S Haloacid dehalogenase-like hydrolase
LEOAPNPK_00155 1e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LEOAPNPK_00156 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEOAPNPK_00157 1.3e-51
LEOAPNPK_00158 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
LEOAPNPK_00159 0.0 3.6.3.8 P P-type ATPase
LEOAPNPK_00161 2.9e-44
LEOAPNPK_00162 1.5e-94 S Protein of unknown function (DUF3990)
LEOAPNPK_00163 4.7e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
LEOAPNPK_00164 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
LEOAPNPK_00165 9.1e-28 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LEOAPNPK_00166 1.9e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEOAPNPK_00167 4.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LEOAPNPK_00168 1.7e-28
LEOAPNPK_00169 4.8e-10 S LPXTG cell wall anchor motif
LEOAPNPK_00170 6.7e-147 S Putative ABC-transporter type IV
LEOAPNPK_00171 2e-79 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
LEOAPNPK_00172 4.7e-54 S ECF transporter, substrate-specific component
LEOAPNPK_00173 2.7e-24 S Domain of unknown function (DUF4430)
LEOAPNPK_00174 4.7e-43 S Domain of unknown function (DUF4430)
LEOAPNPK_00175 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
LEOAPNPK_00176 0.0 oppA E ABC transporter substrate-binding protein
LEOAPNPK_00177 7.1e-176 K AI-2E family transporter
LEOAPNPK_00178 1.2e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
LEOAPNPK_00179 4.1e-18
LEOAPNPK_00180 1.2e-247 G Major Facilitator
LEOAPNPK_00181 2.3e-81 E Zn peptidase
LEOAPNPK_00182 2.7e-41 ps115 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_00183 5.7e-42
LEOAPNPK_00184 2e-52 S Bacteriocin helveticin-J
LEOAPNPK_00185 1.3e-37
LEOAPNPK_00186 4.4e-45
LEOAPNPK_00187 1.8e-136 XK27_08845 S ABC transporter, ATP-binding protein
LEOAPNPK_00188 7.4e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
LEOAPNPK_00189 3.4e-175 ABC-SBP S ABC transporter
LEOAPNPK_00190 7.6e-158 lanM KLT Protein kinase domain
LEOAPNPK_00191 2.9e-54
LEOAPNPK_00192 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
LEOAPNPK_00193 7.7e-103 S TPM domain
LEOAPNPK_00194 6.1e-90 comEB 3.5.4.12 F MafB19-like deaminase
LEOAPNPK_00195 1.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEOAPNPK_00196 1.2e-111 E Belongs to the SOS response-associated peptidase family
LEOAPNPK_00198 7.9e-112
LEOAPNPK_00199 2.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEOAPNPK_00200 2.6e-68 hsp O Belongs to the small heat shock protein (HSP20) family
LEOAPNPK_00201 1.4e-256 pepC 3.4.22.40 E aminopeptidase
LEOAPNPK_00202 1.9e-175 oppF P Belongs to the ABC transporter superfamily
LEOAPNPK_00203 4.2e-200 oppD P Belongs to the ABC transporter superfamily
LEOAPNPK_00204 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEOAPNPK_00205 1.4e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEOAPNPK_00206 1.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEOAPNPK_00207 9.9e-310 oppA E ABC transporter, substratebinding protein
LEOAPNPK_00209 1.2e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEOAPNPK_00210 1.6e-257 pepC 3.4.22.40 E aminopeptidase
LEOAPNPK_00212 3.1e-54
LEOAPNPK_00213 2.4e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEOAPNPK_00214 0.0 XK27_08315 M Sulfatase
LEOAPNPK_00215 7.3e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEOAPNPK_00216 2.1e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LEOAPNPK_00217 1.4e-98 G Aldose 1-epimerase
LEOAPNPK_00218 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEOAPNPK_00219 2.3e-136
LEOAPNPK_00220 9.5e-144
LEOAPNPK_00221 2.2e-179 S Oxidoreductase family, NAD-binding Rossmann fold
LEOAPNPK_00222 3.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LEOAPNPK_00223 0.0 yjbQ P TrkA C-terminal domain protein
LEOAPNPK_00224 3.3e-208 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
LEOAPNPK_00225 1.9e-212 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEOAPNPK_00226 2.4e-43 L transposase activity
LEOAPNPK_00227 5.2e-97 cadD P Cadmium resistance transporter
LEOAPNPK_00229 6e-34 L Type III restriction enzyme, res subunit
LEOAPNPK_00231 0.0 copB 3.6.3.4 P P-type ATPase
LEOAPNPK_00232 3.9e-72 K Copper transport repressor CopY TcrY
LEOAPNPK_00234 8.8e-81 L transposase, IS605 OrfB family
LEOAPNPK_00235 8.9e-123 S SLAP domain
LEOAPNPK_00236 1.9e-20 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LEOAPNPK_00237 3e-78 XK27_02470 K LytTr DNA-binding domain
LEOAPNPK_00238 5.4e-128 liaI S membrane
LEOAPNPK_00239 1.2e-244 L transposase, IS605 OrfB family
LEOAPNPK_00240 3.4e-15
LEOAPNPK_00241 3.4e-206 S Putative peptidoglycan binding domain
LEOAPNPK_00242 8.7e-158 2.7.7.12 C Domain of unknown function (DUF4931)
LEOAPNPK_00243 1.2e-120
LEOAPNPK_00244 8.4e-142 S Belongs to the UPF0246 family
LEOAPNPK_00245 4.9e-142 aroD S Alpha/beta hydrolase family
LEOAPNPK_00246 6e-111 G phosphoglycerate mutase
LEOAPNPK_00247 6.9e-95 ygfC K Bacterial regulatory proteins, tetR family
LEOAPNPK_00248 4.7e-175 hrtB V ABC transporter permease
LEOAPNPK_00249 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
LEOAPNPK_00250 2.8e-276 pipD E Dipeptidase
LEOAPNPK_00251 8e-38
LEOAPNPK_00252 6.3e-111 K WHG domain
LEOAPNPK_00253 1.5e-64 L Resolvase, N-terminal
LEOAPNPK_00254 2.8e-147 L Putative transposase DNA-binding domain
LEOAPNPK_00255 7.1e-95 nqr 1.5.1.36 S NADPH-dependent FMN reductase
LEOAPNPK_00256 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
LEOAPNPK_00257 6e-151 3.1.3.48 T Tyrosine phosphatase family
LEOAPNPK_00258 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LEOAPNPK_00260 4.3e-52 cvpA S Colicin V production protein
LEOAPNPK_00261 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
LEOAPNPK_00262 5.6e-147 noc K Belongs to the ParB family
LEOAPNPK_00263 3.4e-138 soj D Sporulation initiation inhibitor
LEOAPNPK_00264 8.5e-154 spo0J K Belongs to the ParB family
LEOAPNPK_00265 2.8e-44 yyzM S Bacterial protein of unknown function (DUF951)
LEOAPNPK_00266 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEOAPNPK_00267 1.8e-107 XK27_01040 S Protein of unknown function (DUF1129)
LEOAPNPK_00268 8.7e-304 V ABC transporter, ATP-binding protein
LEOAPNPK_00269 0.0 V ABC transporter
LEOAPNPK_00271 1.8e-205 L Probable transposase
LEOAPNPK_00272 3e-39 S HicB family
LEOAPNPK_00273 9.6e-121 K response regulator
LEOAPNPK_00274 4.6e-208 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
LEOAPNPK_00275 2.1e-304 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEOAPNPK_00276 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LEOAPNPK_00277 6.2e-54 S Enterocin A Immunity
LEOAPNPK_00278 2.5e-33
LEOAPNPK_00279 1.2e-25
LEOAPNPK_00280 1e-24
LEOAPNPK_00281 1.2e-271 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
LEOAPNPK_00282 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
LEOAPNPK_00284 9.2e-10
LEOAPNPK_00285 5.9e-38
LEOAPNPK_00286 6.9e-30 yozG K Transcriptional regulator
LEOAPNPK_00287 1.1e-24
LEOAPNPK_00288 4.4e-68
LEOAPNPK_00290 4.9e-29
LEOAPNPK_00291 2.7e-163 natA S ABC transporter, ATP-binding protein
LEOAPNPK_00292 6.7e-218 natB CP ABC-2 family transporter protein
LEOAPNPK_00293 1.8e-136 fruR K DeoR C terminal sensor domain
LEOAPNPK_00294 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LEOAPNPK_00295 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
LEOAPNPK_00296 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
LEOAPNPK_00297 1.4e-148 psaA P Belongs to the bacterial solute-binding protein 9 family
LEOAPNPK_00298 8.8e-116 fhuC P ABC transporter
LEOAPNPK_00299 8.5e-129 znuB U ABC 3 transport family
LEOAPNPK_00300 4.4e-259 lctP C L-lactate permease
LEOAPNPK_00301 6.1e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEOAPNPK_00302 2.4e-95 2.1.1.14 E methionine synthase, vitamin-B12 independent
LEOAPNPK_00303 1.7e-36 2.1.1.14 E methionine synthase, vitamin-B12 independent
LEOAPNPK_00304 6e-70 doc S Prophage maintenance system killer protein
LEOAPNPK_00305 4.9e-31
LEOAPNPK_00306 7.8e-14 Z012_06740 S Fic/DOC family
LEOAPNPK_00307 0.0 pepF E oligoendopeptidase F
LEOAPNPK_00308 1.5e-209 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LEOAPNPK_00309 1.9e-124 S Protein of unknown function (DUF554)
LEOAPNPK_00310 9.6e-89
LEOAPNPK_00311 5e-72 rimL J Acetyltransferase (GNAT) domain
LEOAPNPK_00312 2.5e-62
LEOAPNPK_00313 6.4e-290 S ABC transporter
LEOAPNPK_00314 4.8e-137 thrE S Putative threonine/serine exporter
LEOAPNPK_00315 2.5e-83 S Threonine/Serine exporter, ThrE
LEOAPNPK_00316 4.5e-111 yvpB S Peptidase_C39 like family
LEOAPNPK_00317 3.6e-75
LEOAPNPK_00318 9.2e-175 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEOAPNPK_00319 1.9e-77 nrdI F NrdI Flavodoxin like
LEOAPNPK_00320 1.5e-222 tnpB L Putative transposase DNA-binding domain
LEOAPNPK_00321 3.3e-112
LEOAPNPK_00322 2.9e-279 S O-antigen ligase like membrane protein
LEOAPNPK_00323 2.3e-42
LEOAPNPK_00324 9.3e-95 gmk2 2.7.4.8 F Guanylate kinase homologues.
LEOAPNPK_00325 2.3e-85 M NlpC/P60 family
LEOAPNPK_00326 1.4e-136 M NlpC P60 family protein
LEOAPNPK_00327 2.2e-117 M NlpC/P60 family
LEOAPNPK_00355 1.2e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
LEOAPNPK_00356 2.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
LEOAPNPK_00357 1.5e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEOAPNPK_00358 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEOAPNPK_00359 1.7e-29 secG U Preprotein translocase
LEOAPNPK_00360 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEOAPNPK_00361 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LEOAPNPK_00362 0.0 L Transposase DDE domain
LEOAPNPK_00363 4.3e-59 V ABC-type multidrug transport system, ATPase and permease components
LEOAPNPK_00364 3.4e-09 KLT Protein kinase domain
LEOAPNPK_00365 2.4e-159 V ABC-type multidrug transport system, ATPase and permease components
LEOAPNPK_00366 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEOAPNPK_00367 1.9e-146 tatD L hydrolase, TatD family
LEOAPNPK_00368 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEOAPNPK_00369 2.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEOAPNPK_00370 1.2e-39 veg S Biofilm formation stimulator VEG
LEOAPNPK_00371 3.8e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LEOAPNPK_00372 2.6e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEOAPNPK_00373 5.3e-80
LEOAPNPK_00374 0.0 S SLAP domain
LEOAPNPK_00375 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEOAPNPK_00376 4.7e-171 2.7.1.2 GK ROK family
LEOAPNPK_00377 1.9e-43
LEOAPNPK_00378 1.9e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEOAPNPK_00379 1e-66 S Domain of unknown function (DUF1934)
LEOAPNPK_00380 1.7e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEOAPNPK_00381 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEOAPNPK_00382 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEOAPNPK_00383 9.4e-76 K acetyltransferase
LEOAPNPK_00384 4.4e-285 pipD E Dipeptidase
LEOAPNPK_00385 3.2e-155 msmR K AraC-like ligand binding domain
LEOAPNPK_00386 3.9e-224 pbuX F xanthine permease
LEOAPNPK_00387 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEOAPNPK_00389 8.6e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LEOAPNPK_00390 4.6e-275 D FIVAR domain
LEOAPNPK_00393 7.9e-57 ps115 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_00394 2.7e-19 yjdF S Protein of unknown function (DUF2992)
LEOAPNPK_00395 2.3e-59 hxlR K Transcriptional regulator, HxlR family
LEOAPNPK_00396 1.2e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
LEOAPNPK_00397 2.1e-96 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEOAPNPK_00398 1e-95
LEOAPNPK_00399 2.6e-142 yfeO P Voltage gated chloride channel
LEOAPNPK_00400 1.5e-186 5.3.3.2 C FMN-dependent dehydrogenase
LEOAPNPK_00401 3.1e-51
LEOAPNPK_00402 6.7e-41
LEOAPNPK_00403 7.5e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEOAPNPK_00404 2.3e-298 ybeC E amino acid
LEOAPNPK_00405 1.1e-155 S Sucrose-6F-phosphate phosphohydrolase
LEOAPNPK_00406 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
LEOAPNPK_00407 2.5e-39 rpmE2 J Ribosomal protein L31
LEOAPNPK_00408 1.1e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEOAPNPK_00409 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEOAPNPK_00410 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEOAPNPK_00411 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEOAPNPK_00412 3.4e-129 S (CBS) domain
LEOAPNPK_00413 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LEOAPNPK_00414 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEOAPNPK_00415 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEOAPNPK_00416 1.6e-33 yabO J S4 domain protein
LEOAPNPK_00417 6.8e-60 divIC D Septum formation initiator
LEOAPNPK_00418 6.3e-63 yabR J S1 RNA binding domain
LEOAPNPK_00419 6.9e-242 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEOAPNPK_00420 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEOAPNPK_00421 1.1e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEOAPNPK_00422 2.3e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEOAPNPK_00423 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LEOAPNPK_00425 1.6e-08
LEOAPNPK_00426 1.6e-08
LEOAPNPK_00427 1.6e-08
LEOAPNPK_00429 1.1e-80 yebR 1.8.4.14 T GAF domain-containing protein
LEOAPNPK_00430 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LEOAPNPK_00431 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEOAPNPK_00432 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEOAPNPK_00433 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
LEOAPNPK_00434 1.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEOAPNPK_00435 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEOAPNPK_00436 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEOAPNPK_00437 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LEOAPNPK_00438 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEOAPNPK_00439 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
LEOAPNPK_00440 5.3e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEOAPNPK_00441 1.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEOAPNPK_00442 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEOAPNPK_00443 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEOAPNPK_00444 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEOAPNPK_00445 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEOAPNPK_00446 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
LEOAPNPK_00447 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEOAPNPK_00448 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEOAPNPK_00449 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEOAPNPK_00450 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEOAPNPK_00451 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEOAPNPK_00452 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEOAPNPK_00453 9.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEOAPNPK_00454 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEOAPNPK_00455 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEOAPNPK_00456 2.3e-24 rpmD J Ribosomal protein L30
LEOAPNPK_00457 2.6e-71 rplO J Binds to the 23S rRNA
LEOAPNPK_00458 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEOAPNPK_00459 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEOAPNPK_00460 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEOAPNPK_00461 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LEOAPNPK_00462 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEOAPNPK_00463 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEOAPNPK_00464 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEOAPNPK_00465 1.4e-60 rplQ J Ribosomal protein L17
LEOAPNPK_00466 1.1e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEOAPNPK_00467 5.4e-158 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEOAPNPK_00468 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEOAPNPK_00469 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEOAPNPK_00470 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEOAPNPK_00471 7.9e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
LEOAPNPK_00472 3.4e-149 M Belongs to the glycosyl hydrolase 28 family
LEOAPNPK_00473 4.6e-79 K Acetyltransferase (GNAT) domain
LEOAPNPK_00474 8.8e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
LEOAPNPK_00475 7.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LEOAPNPK_00476 1.1e-133 S membrane transporter protein
LEOAPNPK_00477 5.8e-126 gpmB G Belongs to the phosphoglycerate mutase family
LEOAPNPK_00478 5.1e-162 czcD P cation diffusion facilitator family transporter
LEOAPNPK_00479 1.4e-23
LEOAPNPK_00480 2.9e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LEOAPNPK_00481 1.1e-183 S AAA domain
LEOAPNPK_00482 3.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
LEOAPNPK_00483 1.2e-51
LEOAPNPK_00484 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
LEOAPNPK_00485 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEOAPNPK_00486 1.3e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEOAPNPK_00487 1.7e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEOAPNPK_00488 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEOAPNPK_00489 2.1e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEOAPNPK_00490 4.2e-95 sigH K Belongs to the sigma-70 factor family
LEOAPNPK_00491 1.7e-34
LEOAPNPK_00492 1.3e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
LEOAPNPK_00493 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEOAPNPK_00494 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEOAPNPK_00495 1.1e-101 nusG K Participates in transcription elongation, termination and antitermination
LEOAPNPK_00496 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEOAPNPK_00497 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEOAPNPK_00498 7.3e-158 pstS P Phosphate
LEOAPNPK_00499 8.6e-163 pstC P probably responsible for the translocation of the substrate across the membrane
LEOAPNPK_00500 1.2e-155 pstA P Phosphate transport system permease protein PstA
LEOAPNPK_00501 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEOAPNPK_00502 3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEOAPNPK_00503 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
LEOAPNPK_00504 4.2e-60 L An automated process has identified a potential problem with this gene model
LEOAPNPK_00505 1.7e-12 GT2,GT4 M family 8
LEOAPNPK_00506 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEOAPNPK_00507 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEOAPNPK_00508 3.9e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
LEOAPNPK_00509 3.8e-116 rsmC 2.1.1.172 J Methyltransferase
LEOAPNPK_00510 9e-26
LEOAPNPK_00511 1.1e-89 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEOAPNPK_00512 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEOAPNPK_00513 5.7e-106 2.4.1.58 GT8 M family 8
LEOAPNPK_00514 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
LEOAPNPK_00515 2.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEOAPNPK_00516 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEOAPNPK_00517 1.1e-34 S Protein of unknown function (DUF2508)
LEOAPNPK_00518 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEOAPNPK_00519 8.9e-53 yaaQ S Cyclic-di-AMP receptor
LEOAPNPK_00520 3e-156 holB 2.7.7.7 L DNA polymerase III
LEOAPNPK_00521 1.8e-59 yabA L Involved in initiation control of chromosome replication
LEOAPNPK_00522 7.9e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEOAPNPK_00523 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
LEOAPNPK_00524 2.4e-87 S ECF transporter, substrate-specific component
LEOAPNPK_00525 1.5e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
LEOAPNPK_00526 1.6e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
LEOAPNPK_00527 2.5e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEOAPNPK_00528 6.3e-232 L COG3547 Transposase and inactivated derivatives
LEOAPNPK_00529 1.7e-42
LEOAPNPK_00530 1.4e-30 L COG2963 Transposase and inactivated derivatives
LEOAPNPK_00531 0.0 uup S ABC transporter, ATP-binding protein
LEOAPNPK_00532 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEOAPNPK_00533 1e-184 scrR K helix_turn _helix lactose operon repressor
LEOAPNPK_00534 3.1e-294 scrB 3.2.1.26 GH32 G invertase
LEOAPNPK_00535 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
LEOAPNPK_00536 2.3e-181 M CHAP domain
LEOAPNPK_00537 3.5e-75
LEOAPNPK_00538 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEOAPNPK_00539 2.6e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEOAPNPK_00540 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEOAPNPK_00541 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEOAPNPK_00542 4.5e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEOAPNPK_00543 6.7e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEOAPNPK_00544 9.6e-41 yajC U Preprotein translocase
LEOAPNPK_00545 5.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEOAPNPK_00546 5.9e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEOAPNPK_00547 6.7e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
LEOAPNPK_00548 1.4e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEOAPNPK_00549 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEOAPNPK_00550 2e-42 yrzL S Belongs to the UPF0297 family
LEOAPNPK_00551 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEOAPNPK_00552 1.1e-50 yrzB S Belongs to the UPF0473 family
LEOAPNPK_00553 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEOAPNPK_00554 3.5e-54 trxA O Belongs to the thioredoxin family
LEOAPNPK_00555 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LEOAPNPK_00556 1.1e-71 yslB S Protein of unknown function (DUF2507)
LEOAPNPK_00557 1.7e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LEOAPNPK_00558 9.6e-112 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEOAPNPK_00559 2.8e-146 ykuT M mechanosensitive ion channel
LEOAPNPK_00560 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEOAPNPK_00561 1.3e-36
LEOAPNPK_00562 9.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LEOAPNPK_00563 4.9e-182 ccpA K catabolite control protein A
LEOAPNPK_00564 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEOAPNPK_00565 4.3e-55
LEOAPNPK_00566 1.5e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LEOAPNPK_00567 1.7e-105 yutD S Protein of unknown function (DUF1027)
LEOAPNPK_00568 4.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEOAPNPK_00569 3.1e-99 S Protein of unknown function (DUF1461)
LEOAPNPK_00570 2.3e-27 L Transposase
LEOAPNPK_00571 3.5e-118 V ABC transporter transmembrane region
LEOAPNPK_00572 4.7e-114 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LEOAPNPK_00573 3.3e-40 cycA E Amino acid permease
LEOAPNPK_00574 3.7e-180 cycA E Amino acid permease
LEOAPNPK_00575 2.4e-248 yifK E Amino acid permease
LEOAPNPK_00576 5.8e-176 S PFAM Archaeal ATPase
LEOAPNPK_00577 1.2e-140 puuD S peptidase C26
LEOAPNPK_00578 7.2e-232 steT_1 E amino acid
LEOAPNPK_00579 3.8e-190 asnA 6.3.1.1 F aspartate--ammonia ligase
LEOAPNPK_00580 6.7e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
LEOAPNPK_00583 2e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEOAPNPK_00584 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEOAPNPK_00585 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEOAPNPK_00586 1.2e-36 hicA S HicA toxin of bacterial toxin-antitoxin,
LEOAPNPK_00587 9.2e-56 S protein encoded in hypervariable junctions of pilus gene clusters
LEOAPNPK_00589 4.8e-119 ropB K Helix-turn-helix domain
LEOAPNPK_00590 2.3e-100 S SLAP domain
LEOAPNPK_00591 8.4e-188 S SLAP domain
LEOAPNPK_00592 1.8e-60 yjeM E Amino Acid
LEOAPNPK_00593 4e-198 yjeM E Amino Acid
LEOAPNPK_00594 8.4e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEOAPNPK_00595 6.4e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
LEOAPNPK_00596 3.4e-48 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LEOAPNPK_00597 8.2e-117 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LEOAPNPK_00598 1.3e-51 S Iron-sulfur cluster assembly protein
LEOAPNPK_00599 5.5e-153 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LEOAPNPK_00600 3.4e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
LEOAPNPK_00601 3.7e-45
LEOAPNPK_00602 4.2e-286 lsa S ABC transporter
LEOAPNPK_00603 3.3e-37 clcA P chloride
LEOAPNPK_00604 3.4e-19 clcA P chloride
LEOAPNPK_00605 1.1e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEOAPNPK_00606 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEOAPNPK_00607 6.3e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEOAPNPK_00608 4.6e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEOAPNPK_00609 1.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LEOAPNPK_00610 1.3e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEOAPNPK_00611 2.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEOAPNPK_00612 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LEOAPNPK_00613 9.9e-251 lctP C L-lactate permease
LEOAPNPK_00614 6.1e-149 glcU U sugar transport
LEOAPNPK_00615 1.3e-44
LEOAPNPK_00616 5.2e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LEOAPNPK_00617 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LEOAPNPK_00618 1.2e-42 S Alpha beta hydrolase
LEOAPNPK_00619 1.9e-37
LEOAPNPK_00620 2.6e-52
LEOAPNPK_00621 1.7e-148 S haloacid dehalogenase-like hydrolase
LEOAPNPK_00622 2e-291 V ABC-type multidrug transport system, ATPase and permease components
LEOAPNPK_00623 8e-280 V ABC-type multidrug transport system, ATPase and permease components
LEOAPNPK_00624 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
LEOAPNPK_00625 8.5e-178 I Carboxylesterase family
LEOAPNPK_00627 1.9e-207 M Glycosyl hydrolases family 25
LEOAPNPK_00628 1.6e-160 cinI S Serine hydrolase (FSH1)
LEOAPNPK_00629 3.6e-300 S Predicted membrane protein (DUF2207)
LEOAPNPK_00630 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LEOAPNPK_00632 2.7e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
LEOAPNPK_00633 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEOAPNPK_00634 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LEOAPNPK_00635 7.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LEOAPNPK_00636 6.6e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LEOAPNPK_00637 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEOAPNPK_00638 3.4e-71 yqhY S Asp23 family, cell envelope-related function
LEOAPNPK_00639 2.1e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEOAPNPK_00640 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEOAPNPK_00641 7.6e-194 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEOAPNPK_00642 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEOAPNPK_00643 2.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEOAPNPK_00644 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LEOAPNPK_00645 1.5e-308 recN L May be involved in recombinational repair of damaged DNA
LEOAPNPK_00646 1.1e-77 6.3.3.2 S ASCH
LEOAPNPK_00647 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
LEOAPNPK_00648 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEOAPNPK_00649 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEOAPNPK_00650 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEOAPNPK_00651 6.1e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEOAPNPK_00652 1.3e-139 stp 3.1.3.16 T phosphatase
LEOAPNPK_00653 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LEOAPNPK_00654 1.3e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEOAPNPK_00655 6.5e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LEOAPNPK_00656 1.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
LEOAPNPK_00657 1.4e-30
LEOAPNPK_00658 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LEOAPNPK_00659 4e-57 asp S Asp23 family, cell envelope-related function
LEOAPNPK_00660 4.4e-305 yloV S DAK2 domain fusion protein YloV
LEOAPNPK_00661 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEOAPNPK_00662 2.7e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEOAPNPK_00663 1.8e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEOAPNPK_00664 1.1e-192 oppD P Belongs to the ABC transporter superfamily
LEOAPNPK_00665 8.8e-168 oppF P Belongs to the ABC transporter superfamily
LEOAPNPK_00666 9.8e-172 oppB P ABC transporter permease
LEOAPNPK_00667 6.2e-131 oppC P Binding-protein-dependent transport system inner membrane component
LEOAPNPK_00668 1.3e-63 oppA E ABC transporter substrate-binding protein
LEOAPNPK_00669 5.6e-239 oppA E ABC transporter substrate-binding protein
LEOAPNPK_00670 4.9e-310 oppA E ABC transporter substrate-binding protein
LEOAPNPK_00671 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEOAPNPK_00672 0.0 smc D Required for chromosome condensation and partitioning
LEOAPNPK_00673 7.8e-164 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEOAPNPK_00674 5.5e-288 pipD E Dipeptidase
LEOAPNPK_00675 4.2e-08
LEOAPNPK_00676 2.4e-133 cysA V ABC transporter, ATP-binding protein
LEOAPNPK_00677 0.0 V FtsX-like permease family
LEOAPNPK_00678 3.2e-259 yfnA E amino acid
LEOAPNPK_00679 1.2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEOAPNPK_00680 5.8e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEOAPNPK_00681 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LEOAPNPK_00682 2.2e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEOAPNPK_00683 5e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LEOAPNPK_00684 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEOAPNPK_00685 1.4e-214 S SLAP domain
LEOAPNPK_00686 1.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
LEOAPNPK_00687 3.7e-145 E GDSL-like Lipase/Acylhydrolase family
LEOAPNPK_00688 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEOAPNPK_00689 3e-38 ynzC S UPF0291 protein
LEOAPNPK_00690 3.3e-30 yneF S Uncharacterised protein family (UPF0154)
LEOAPNPK_00691 0.0 mdlA V ABC transporter
LEOAPNPK_00692 0.0 mdlB V ABC transporter
LEOAPNPK_00693 0.0 pepO 3.4.24.71 O Peptidase family M13
LEOAPNPK_00694 3.1e-22 npr 1.11.1.1 C NADH oxidase
LEOAPNPK_00695 4.4e-85 dps P Belongs to the Dps family
LEOAPNPK_00696 1.1e-272 oppA E ABC transporter substrate-binding protein
LEOAPNPK_00697 8.7e-43 oppA E ABC transporter substrate-binding protein
LEOAPNPK_00698 1.9e-131 S SLAP domain
LEOAPNPK_00699 3.1e-99 L An automated process has identified a potential problem with this gene model
LEOAPNPK_00700 4.1e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LEOAPNPK_00701 1.9e-112 plsC 2.3.1.51 I Acyltransferase
LEOAPNPK_00702 6.3e-193 yabB 2.1.1.223 L Methyltransferase small domain
LEOAPNPK_00703 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
LEOAPNPK_00704 8.3e-185 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEOAPNPK_00705 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LEOAPNPK_00706 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEOAPNPK_00707 1.6e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEOAPNPK_00708 9.6e-136 cdsA 2.7.7.41 I Belongs to the CDS family
LEOAPNPK_00709 7.5e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LEOAPNPK_00710 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEOAPNPK_00711 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEOAPNPK_00712 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
LEOAPNPK_00713 4.9e-197 nusA K Participates in both transcription termination and antitermination
LEOAPNPK_00714 8.8e-47 ylxR K Protein of unknown function (DUF448)
LEOAPNPK_00715 3.2e-47 rplGA J ribosomal protein
LEOAPNPK_00716 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEOAPNPK_00717 3e-60 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEOAPNPK_00718 3.4e-158 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEOAPNPK_00719 9.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LEOAPNPK_00720 4.5e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEOAPNPK_00721 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEOAPNPK_00722 0.0 dnaK O Heat shock 70 kDa protein
LEOAPNPK_00723 5.8e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEOAPNPK_00724 9.3e-80 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
LEOAPNPK_00725 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEOAPNPK_00726 4.5e-102 srtA 3.4.22.70 M sortase family
LEOAPNPK_00727 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LEOAPNPK_00728 3.1e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEOAPNPK_00729 4.6e-89 oppA E ABC transporter substrate-binding protein
LEOAPNPK_00731 1.2e-202 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
LEOAPNPK_00732 1.5e-184 S Bacterial protein of unknown function (DUF871)
LEOAPNPK_00733 8.9e-46 ybhL S Belongs to the BI1 family
LEOAPNPK_00734 1.5e-12 ybhL S Belongs to the BI1 family
LEOAPNPK_00736 5.4e-09 S Metal binding domain of Ada
LEOAPNPK_00737 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
LEOAPNPK_00738 9e-137 lysR5 K LysR substrate binding domain
LEOAPNPK_00739 3.7e-77 arcA 3.5.3.6 E Arginine
LEOAPNPK_00740 1e-136 arcA 3.5.3.6 E Arginine
LEOAPNPK_00741 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LEOAPNPK_00742 1.2e-107 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
LEOAPNPK_00743 2e-97 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
LEOAPNPK_00744 1.3e-215 S Sterol carrier protein domain
LEOAPNPK_00745 1e-20
LEOAPNPK_00746 2e-109 K LysR substrate binding domain
LEOAPNPK_00747 1.1e-98
LEOAPNPK_00748 7.3e-118 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
LEOAPNPK_00749 3.4e-11 S Uncharacterised protein family (UPF0236)
LEOAPNPK_00750 3.9e-72 L IS1381, transposase OrfA
LEOAPNPK_00753 1.2e-142 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEOAPNPK_00755 7.6e-39 KQ helix_turn_helix, mercury resistance
LEOAPNPK_00756 9.5e-81 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEOAPNPK_00758 2.5e-106 3.2.2.20 K acetyltransferase
LEOAPNPK_00759 2e-157 S Archaea bacterial proteins of unknown function
LEOAPNPK_00760 7.8e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LEOAPNPK_00761 8.6e-24
LEOAPNPK_00762 1.1e-150
LEOAPNPK_00763 2.3e-267 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
LEOAPNPK_00764 1.8e-136 glvR K Helix-turn-helix domain, rpiR family
LEOAPNPK_00765 1.5e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
LEOAPNPK_00766 7.7e-09
LEOAPNPK_00767 8.7e-66 2.7.1.191 G PTS system fructose IIA component
LEOAPNPK_00768 0.0 3.6.3.8 P P-type ATPase
LEOAPNPK_00769 2.9e-125
LEOAPNPK_00770 9.1e-242 S response to antibiotic
LEOAPNPK_00771 3.2e-126 pgm3 G Phosphoglycerate mutase family
LEOAPNPK_00772 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
LEOAPNPK_00773 0.0 helD 3.6.4.12 L DNA helicase
LEOAPNPK_00774 4.2e-110 glnP P ABC transporter permease
LEOAPNPK_00775 7.1e-107 glnQ 3.6.3.21 E ABC transporter
LEOAPNPK_00776 1.1e-139 aatB ET ABC transporter substrate-binding protein
LEOAPNPK_00777 3.7e-73 yjcF S Acetyltransferase (GNAT) domain
LEOAPNPK_00778 1.1e-98 E GDSL-like Lipase/Acylhydrolase
LEOAPNPK_00779 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
LEOAPNPK_00780 4.4e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEOAPNPK_00781 1.5e-101 S Peptidase propeptide and YPEB domain
LEOAPNPK_00782 9.9e-62 ypaA S Protein of unknown function (DUF1304)
LEOAPNPK_00783 3.4e-310 oppA3 E ABC transporter, substratebinding protein
LEOAPNPK_00784 8.9e-242 V ABC transporter transmembrane region
LEOAPNPK_00785 6.2e-76 yybA 2.3.1.57 K Transcriptional regulator
LEOAPNPK_00786 1.3e-96 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
LEOAPNPK_00787 1.5e-101 S Peptidase propeptide and YPEB domain
LEOAPNPK_00788 1.6e-86 S Peptidase propeptide and YPEB domain
LEOAPNPK_00789 2.2e-246 T GHKL domain
LEOAPNPK_00790 6.3e-131 T Transcriptional regulatory protein, C terminal
LEOAPNPK_00791 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
LEOAPNPK_00792 4.2e-276 V ABC transporter transmembrane region
LEOAPNPK_00793 4.6e-129 S PAS domain
LEOAPNPK_00794 1.4e-13
LEOAPNPK_00795 9e-141 pnuC H nicotinamide mononucleotide transporter
LEOAPNPK_00796 1.1e-72 S Protein of unknown function (DUF3290)
LEOAPNPK_00797 3e-116 yviA S Protein of unknown function (DUF421)
LEOAPNPK_00798 2.4e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LEOAPNPK_00799 1.4e-181 dnaQ 2.7.7.7 L EXOIII
LEOAPNPK_00800 4.2e-158 endA F DNA RNA non-specific endonuclease
LEOAPNPK_00801 1.8e-283 pipD E Dipeptidase
LEOAPNPK_00802 9.3e-203 malK P ATPases associated with a variety of cellular activities
LEOAPNPK_00803 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
LEOAPNPK_00804 1.4e-145 gtsC P Binding-protein-dependent transport system inner membrane component
LEOAPNPK_00805 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
LEOAPNPK_00806 2.5e-239 G Bacterial extracellular solute-binding protein
LEOAPNPK_00807 1.8e-154 corA P CorA-like Mg2+ transporter protein
LEOAPNPK_00808 2e-148 3.5.2.6 V Beta-lactamase enzyme family
LEOAPNPK_00809 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
LEOAPNPK_00810 0.0 ydgH S MMPL family
LEOAPNPK_00812 1.3e-25 K Acetyltransferase (GNAT) domain
LEOAPNPK_00813 2.6e-162
LEOAPNPK_00814 1.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
LEOAPNPK_00815 2.4e-92 F Nucleoside 2-deoxyribosyltransferase
LEOAPNPK_00816 3.8e-159 hipB K Helix-turn-helix
LEOAPNPK_00817 6.5e-153 I alpha/beta hydrolase fold
LEOAPNPK_00818 1.8e-110 yjbF S SNARE associated Golgi protein
LEOAPNPK_00819 3.4e-100 J Acetyltransferase (GNAT) domain
LEOAPNPK_00820 2.8e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEOAPNPK_00821 1.3e-31 UW LPXTG-motif cell wall anchor domain protein
LEOAPNPK_00822 9.6e-45 UW LPXTG-motif cell wall anchor domain protein
LEOAPNPK_00823 2e-178 UW LPXTG-motif cell wall anchor domain protein
LEOAPNPK_00824 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
LEOAPNPK_00825 5.9e-185 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
LEOAPNPK_00826 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LEOAPNPK_00827 4.5e-126 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
LEOAPNPK_00828 6e-26 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
LEOAPNPK_00829 5.7e-106 K Transcriptional regulator, AbiEi antitoxin
LEOAPNPK_00830 7.2e-89 K Periplasmic binding protein-like domain
LEOAPNPK_00831 9.9e-62 K Periplasmic binding protein-like domain
LEOAPNPK_00832 0.0 S PglZ domain
LEOAPNPK_00833 3.1e-29 K Helix-turn-helix
LEOAPNPK_00834 3e-30 E IrrE N-terminal-like domain
LEOAPNPK_00835 1.6e-46 S Domain of unknown function (DUF4417)
LEOAPNPK_00836 4.7e-24
LEOAPNPK_00839 0.0 2.1.1.72 V Eco57I restriction-modification methylase
LEOAPNPK_00840 1.1e-223 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
LEOAPNPK_00841 2.4e-88 S Domain of unknown function (DUF1788)
LEOAPNPK_00842 1.1e-83 S Putative inner membrane protein (DUF1819)
LEOAPNPK_00843 1.5e-274 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEOAPNPK_00844 1.9e-59 L COG2963 Transposase and inactivated derivatives
LEOAPNPK_00845 4.4e-43
LEOAPNPK_00846 3.8e-221 L COG3547 Transposase and inactivated derivatives
LEOAPNPK_00847 9e-124 L Transposase
LEOAPNPK_00848 2.3e-69 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEOAPNPK_00849 2.9e-224 S Cysteine-rich secretory protein family
LEOAPNPK_00850 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LEOAPNPK_00851 3.1e-112
LEOAPNPK_00852 9.1e-201 yibE S overlaps another CDS with the same product name
LEOAPNPK_00853 3.4e-130 yibF S overlaps another CDS with the same product name
LEOAPNPK_00854 1.1e-150 I alpha/beta hydrolase fold
LEOAPNPK_00855 0.0 G Belongs to the glycosyl hydrolase 31 family
LEOAPNPK_00856 1.7e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEOAPNPK_00857 9.8e-46
LEOAPNPK_00858 1.5e-61 S Bacterial toxin of type II toxin-antitoxin system, YafQ
LEOAPNPK_00859 2e-274 S Archaea bacterial proteins of unknown function
LEOAPNPK_00861 3.6e-90 ntd 2.4.2.6 F Nucleoside
LEOAPNPK_00862 7e-89 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEOAPNPK_00863 2.6e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
LEOAPNPK_00864 5.2e-84 uspA T universal stress protein
LEOAPNPK_00865 1.2e-150 phnD P Phosphonate ABC transporter
LEOAPNPK_00866 4.1e-136 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LEOAPNPK_00867 2.8e-124 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
LEOAPNPK_00868 2.2e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
LEOAPNPK_00869 3.3e-106 tag 3.2.2.20 L glycosylase
LEOAPNPK_00870 8.7e-84
LEOAPNPK_00871 4.2e-272 S Calcineurin-like phosphoesterase
LEOAPNPK_00872 0.0 asnB 6.3.5.4 E Asparagine synthase
LEOAPNPK_00873 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
LEOAPNPK_00874 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LEOAPNPK_00875 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LEOAPNPK_00876 4.5e-103 S Iron-sulfur cluster assembly protein
LEOAPNPK_00877 3.4e-230 XK27_04775 S PAS domain
LEOAPNPK_00878 1.4e-210 yttB EGP Major facilitator Superfamily
LEOAPNPK_00879 0.0 pepO 3.4.24.71 O Peptidase family M13
LEOAPNPK_00880 0.0 kup P Transport of potassium into the cell
LEOAPNPK_00881 1.1e-74
LEOAPNPK_00882 2.1e-45 S PFAM Archaeal ATPase
LEOAPNPK_00883 2.3e-10 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LEOAPNPK_00884 3.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
LEOAPNPK_00885 5.9e-45
LEOAPNPK_00887 2.8e-221 tnpB L Putative transposase DNA-binding domain
LEOAPNPK_00888 5.5e-30
LEOAPNPK_00889 5.2e-38 S Protein of unknown function (DUF2922)
LEOAPNPK_00890 6.4e-191 S SLAP domain
LEOAPNPK_00891 6.2e-189 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LEOAPNPK_00892 7.8e-73
LEOAPNPK_00894 2.5e-86 K DNA-templated transcription, initiation
LEOAPNPK_00895 1.5e-25
LEOAPNPK_00896 2.6e-150 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LEOAPNPK_00897 4.4e-62
LEOAPNPK_00898 6.5e-81 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_00900 5.1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEOAPNPK_00901 4.3e-214 iscS2 2.8.1.7 E Aminotransferase class V
LEOAPNPK_00902 6.2e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEOAPNPK_00903 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEOAPNPK_00904 9.9e-85 yueI S Protein of unknown function (DUF1694)
LEOAPNPK_00905 7.4e-239 rarA L recombination factor protein RarA
LEOAPNPK_00906 3.5e-37
LEOAPNPK_00907 3.7e-76 usp6 T universal stress protein
LEOAPNPK_00908 4.6e-126 S zinc-ribbon domain
LEOAPNPK_00909 8.9e-192
LEOAPNPK_00910 5.9e-137 S response to antibiotic
LEOAPNPK_00911 7.7e-97 acfD M Membrane
LEOAPNPK_00913 2.3e-138 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
LEOAPNPK_00914 1.2e-58
LEOAPNPK_00915 1.2e-216 rodA D Belongs to the SEDS family
LEOAPNPK_00916 1.5e-33 S Protein of unknown function (DUF2969)
LEOAPNPK_00917 5.9e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LEOAPNPK_00918 2.5e-178 mbl D Cell shape determining protein MreB Mrl
LEOAPNPK_00919 4.1e-31 ywzB S Protein of unknown function (DUF1146)
LEOAPNPK_00920 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LEOAPNPK_00921 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEOAPNPK_00922 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEOAPNPK_00923 5.7e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEOAPNPK_00924 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEOAPNPK_00925 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEOAPNPK_00926 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEOAPNPK_00927 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
LEOAPNPK_00928 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEOAPNPK_00929 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEOAPNPK_00930 2.5e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEOAPNPK_00931 6.9e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEOAPNPK_00932 4.9e-113 tdk 2.7.1.21 F thymidine kinase
LEOAPNPK_00933 1.3e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
LEOAPNPK_00936 1e-195 ampC V Beta-lactamase
LEOAPNPK_00937 6.9e-219 EGP Major facilitator Superfamily
LEOAPNPK_00938 2.2e-254 pgi 5.3.1.9 G Belongs to the GPI family
LEOAPNPK_00939 3.8e-105 vanZ V VanZ like family
LEOAPNPK_00940 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LEOAPNPK_00941 3.6e-266 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
LEOAPNPK_00942 2e-129 K Transcriptional regulatory protein, C terminal
LEOAPNPK_00943 1.3e-66 S SdpI/YhfL protein family
LEOAPNPK_00944 1e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
LEOAPNPK_00945 2.7e-224 patB 4.4.1.8 E Aminotransferase, class I
LEOAPNPK_00946 4e-111 M Protein of unknown function (DUF3737)
LEOAPNPK_00948 5.4e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEOAPNPK_00949 3.5e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
LEOAPNPK_00950 1.6e-21
LEOAPNPK_00951 1.5e-76 comGF U Putative Competence protein ComGF
LEOAPNPK_00952 2.3e-41
LEOAPNPK_00953 7.4e-71
LEOAPNPK_00954 3.1e-43 comGC U competence protein ComGC
LEOAPNPK_00955 2.7e-172 comGB NU type II secretion system
LEOAPNPK_00956 1.9e-178 comGA NU Type II IV secretion system protein
LEOAPNPK_00957 8.9e-133 yebC K Transcriptional regulatory protein
LEOAPNPK_00958 2e-94 S VanZ like family
LEOAPNPK_00959 3.2e-110 ylbE GM NAD(P)H-binding
LEOAPNPK_00960 9.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEOAPNPK_00962 1.7e-304 E Amino acid permease
LEOAPNPK_00963 3.4e-177 D Alpha beta
LEOAPNPK_00964 1.9e-299 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEOAPNPK_00965 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEOAPNPK_00966 1.7e-143 licT K CAT RNA binding domain
LEOAPNPK_00967 1.8e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LEOAPNPK_00968 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEOAPNPK_00969 2.5e-119
LEOAPNPK_00970 1.8e-75 K Penicillinase repressor
LEOAPNPK_00971 1.4e-147 S hydrolase
LEOAPNPK_00972 9e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEOAPNPK_00973 2e-172 ybbR S YbbR-like protein
LEOAPNPK_00974 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEOAPNPK_00975 4.7e-207 potD P ABC transporter
LEOAPNPK_00976 2.1e-127 potC P ABC transporter permease
LEOAPNPK_00977 5.4e-131 potB P ABC transporter permease
LEOAPNPK_00978 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LEOAPNPK_00979 1.2e-163 murB 1.3.1.98 M Cell wall formation
LEOAPNPK_00980 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
LEOAPNPK_00981 1.4e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
LEOAPNPK_00982 6.3e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LEOAPNPK_00983 3.7e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEOAPNPK_00984 1.8e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
LEOAPNPK_00985 1.2e-94
LEOAPNPK_00986 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEOAPNPK_00987 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LEOAPNPK_00988 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEOAPNPK_00989 1.5e-189 cggR K Putative sugar-binding domain
LEOAPNPK_00991 2.4e-289
LEOAPNPK_00992 5e-273 ycaM E amino acid
LEOAPNPK_00993 4e-139 S Cysteine-rich secretory protein family
LEOAPNPK_00994 2.6e-33 S Protein of unknown function (DUF3021)
LEOAPNPK_00995 6.7e-46 K LytTr DNA-binding domain
LEOAPNPK_00996 3.4e-91 cylB V ABC-2 type transporter
LEOAPNPK_00997 2.8e-117 cylA V ABC transporter
LEOAPNPK_00998 1.4e-77 K MerR HTH family regulatory protein
LEOAPNPK_00999 6.4e-263 lmrB EGP Major facilitator Superfamily
LEOAPNPK_01000 4.3e-95 S Domain of unknown function (DUF4811)
LEOAPNPK_01001 4.3e-130 ybbM S Uncharacterised protein family (UPF0014)
LEOAPNPK_01002 4.9e-111 ybbL S ABC transporter, ATP-binding protein
LEOAPNPK_01003 0.0 S SH3-like domain
LEOAPNPK_01004 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEOAPNPK_01005 2.1e-171 whiA K May be required for sporulation
LEOAPNPK_01006 1.2e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LEOAPNPK_01007 6.2e-165 rapZ S Displays ATPase and GTPase activities
LEOAPNPK_01008 1.1e-90 S Short repeat of unknown function (DUF308)
LEOAPNPK_01009 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEOAPNPK_01010 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEOAPNPK_01011 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LEOAPNPK_01012 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEOAPNPK_01013 3.3e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LEOAPNPK_01014 4.6e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEOAPNPK_01015 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEOAPNPK_01016 5.1e-17
LEOAPNPK_01017 4.9e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEOAPNPK_01018 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEOAPNPK_01019 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEOAPNPK_01020 2.5e-132 comFC S Competence protein
LEOAPNPK_01021 3e-245 comFA L Helicase C-terminal domain protein
LEOAPNPK_01022 1.9e-118 yvyE 3.4.13.9 S YigZ family
LEOAPNPK_01023 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
LEOAPNPK_01024 5.7e-220 rny S Endoribonuclease that initiates mRNA decay
LEOAPNPK_01025 8.5e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEOAPNPK_01026 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEOAPNPK_01027 5.2e-97 ymfM S Helix-turn-helix domain
LEOAPNPK_01028 1.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
LEOAPNPK_01029 3.9e-237 S Peptidase M16
LEOAPNPK_01030 2.6e-222 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
LEOAPNPK_01031 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LEOAPNPK_01032 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
LEOAPNPK_01033 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEOAPNPK_01034 4.9e-213 yubA S AI-2E family transporter
LEOAPNPK_01035 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
LEOAPNPK_01036 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
LEOAPNPK_01037 1e-113 3.6.1.27 I Acid phosphatase homologues
LEOAPNPK_01038 4.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
LEOAPNPK_01039 0.0 uvrA3 L excinuclease ABC, A subunit
LEOAPNPK_01040 3.4e-82 C Flavodoxin
LEOAPNPK_01041 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
LEOAPNPK_01042 6.7e-245 ynbB 4.4.1.1 P aluminum resistance
LEOAPNPK_01043 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
LEOAPNPK_01044 1.7e-284 E Amino acid permease
LEOAPNPK_01045 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
LEOAPNPK_01046 1.3e-273 pepV 3.5.1.18 E dipeptidase PepV
LEOAPNPK_01047 1.2e-116 mmuP E amino acid
LEOAPNPK_01048 2.9e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
LEOAPNPK_01049 2.7e-64 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEOAPNPK_01050 7.9e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEOAPNPK_01051 1.1e-152 xerD L Phage integrase, N-terminal SAM-like domain
LEOAPNPK_01052 5.4e-63 M LysM domain protein
LEOAPNPK_01053 3.7e-44 S aldo-keto reductase (NADP) activity
LEOAPNPK_01054 9.8e-61 C Aldo keto reductase
LEOAPNPK_01055 1.8e-180 lacX 5.1.3.3 G Aldose 1-epimerase
LEOAPNPK_01056 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEOAPNPK_01057 3.3e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEOAPNPK_01058 2.2e-141 xerC D Phage integrase, N-terminal SAM-like domain
LEOAPNPK_01059 2.7e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LEOAPNPK_01060 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEOAPNPK_01061 1e-151 dprA LU DNA protecting protein DprA
LEOAPNPK_01062 2.3e-131 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEOAPNPK_01063 7.3e-155 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEOAPNPK_01064 5.9e-181 yjcE P Sodium proton antiporter
LEOAPNPK_01065 3.6e-40 yjcE P NhaP-type Na H and K H
LEOAPNPK_01066 7.1e-36 yozE S Belongs to the UPF0346 family
LEOAPNPK_01067 9.8e-144 DegV S Uncharacterised protein, DegV family COG1307
LEOAPNPK_01068 1.2e-107 hlyIII S protein, hemolysin III
LEOAPNPK_01069 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEOAPNPK_01070 3.9e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEOAPNPK_01071 1.9e-86 3.4.21.96 S SLAP domain
LEOAPNPK_01072 1.9e-149 yagE E Amino acid permease
LEOAPNPK_01073 3.5e-26 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
LEOAPNPK_01074 3.1e-26 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
LEOAPNPK_01075 2.8e-73 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
LEOAPNPK_01076 2.1e-145 2.4.2.3 F Phosphorylase superfamily
LEOAPNPK_01077 6.9e-144 2.4.2.3 F Phosphorylase superfamily
LEOAPNPK_01078 9.3e-81 S AAA domain
LEOAPNPK_01079 1.5e-124 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
LEOAPNPK_01080 3e-61
LEOAPNPK_01081 3.7e-73 yxaM EGP Major facilitator Superfamily
LEOAPNPK_01082 2.8e-140 S Alpha/beta hydrolase family
LEOAPNPK_01083 4.5e-94 rimL J Acetyltransferase (GNAT) domain
LEOAPNPK_01084 0.0 lacS G Transporter
LEOAPNPK_01085 0.0 lacZ 3.2.1.23 G -beta-galactosidase
LEOAPNPK_01086 8.1e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEOAPNPK_01087 2.8e-287 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LEOAPNPK_01088 1.6e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LEOAPNPK_01089 5.5e-36
LEOAPNPK_01090 1.5e-159 scrR K Periplasmic binding protein domain
LEOAPNPK_01091 7.1e-239 msmE G Bacterial extracellular solute-binding protein
LEOAPNPK_01092 4.8e-157 msmF P Binding-protein-dependent transport system inner membrane component
LEOAPNPK_01093 5.2e-153 msmG P Binding-protein-dependent transport system inner membrane component
LEOAPNPK_01094 2.8e-210 msmX P Belongs to the ABC transporter superfamily
LEOAPNPK_01095 0.0 rafA 3.2.1.22 G alpha-galactosidase
LEOAPNPK_01096 4.6e-282 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
LEOAPNPK_01097 1.3e-113 2.7.6.5 T Region found in RelA / SpoT proteins
LEOAPNPK_01098 3.8e-106 K response regulator
LEOAPNPK_01099 3.1e-221 sptS 2.7.13.3 T Histidine kinase
LEOAPNPK_01100 1.2e-208 EGP Major facilitator Superfamily
LEOAPNPK_01101 2.9e-69 O OsmC-like protein
LEOAPNPK_01102 4e-95 S Protein of unknown function (DUF805)
LEOAPNPK_01103 2.2e-78
LEOAPNPK_01104 8.5e-284
LEOAPNPK_01105 1.2e-137 S Fic/DOC family
LEOAPNPK_01106 3.4e-33
LEOAPNPK_01107 3.6e-63
LEOAPNPK_01110 1.3e-118
LEOAPNPK_01111 1.3e-104 pncA Q Isochorismatase family
LEOAPNPK_01113 6.2e-35
LEOAPNPK_01114 0.0 snf 2.7.11.1 KL domain protein
LEOAPNPK_01115 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEOAPNPK_01116 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEOAPNPK_01117 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEOAPNPK_01118 2.1e-182 K Transcriptional regulator
LEOAPNPK_01119 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
LEOAPNPK_01120 1.1e-112 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEOAPNPK_01121 4e-57 K Helix-turn-helix domain
LEOAPNPK_01124 3.6e-81 XK27_04435 3.5.4.5 J FR47-like protein
LEOAPNPK_01125 1.4e-36 S Cytochrome B5
LEOAPNPK_01126 4.6e-168 arbZ I Phosphate acyltransferases
LEOAPNPK_01127 6e-182 arbY M Glycosyl transferase family 8
LEOAPNPK_01128 4.5e-185 arbY M Glycosyl transferase family 8
LEOAPNPK_01129 1.2e-157 arbx M Glycosyl transferase family 8
LEOAPNPK_01130 3.2e-149 arbV 2.3.1.51 I Acyl-transferase
LEOAPNPK_01132 4.9e-34
LEOAPNPK_01134 4.8e-131 K response regulator
LEOAPNPK_01135 3.8e-305 vicK 2.7.13.3 T Histidine kinase
LEOAPNPK_01136 3.7e-257 yycH S YycH protein
LEOAPNPK_01137 3.4e-149 yycI S YycH protein
LEOAPNPK_01138 8.2e-148 vicX 3.1.26.11 S domain protein
LEOAPNPK_01139 3.3e-151 htrA 3.4.21.107 O serine protease
LEOAPNPK_01140 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEOAPNPK_01141 2.8e-99 G Peptidase_C39 like family
LEOAPNPK_01142 6e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
LEOAPNPK_01143 1.1e-76 P Cobalt transport protein
LEOAPNPK_01144 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
LEOAPNPK_01145 7.9e-174 K helix_turn_helix, arabinose operon control protein
LEOAPNPK_01146 6.6e-162 htpX O Belongs to the peptidase M48B family
LEOAPNPK_01147 1e-96 lemA S LemA family
LEOAPNPK_01148 4e-193 ybiR P Citrate transporter
LEOAPNPK_01149 2e-70 S Iron-sulphur cluster biosynthesis
LEOAPNPK_01150 6.2e-84 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
LEOAPNPK_01151 6.9e-190 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
LEOAPNPK_01152 1.2e-17
LEOAPNPK_01153 2.6e-115
LEOAPNPK_01155 5.2e-216 ydaM M Glycosyl transferase
LEOAPNPK_01156 5.2e-177 G Glycosyl hydrolases family 8
LEOAPNPK_01157 1.4e-121 yfbR S HD containing hydrolase-like enzyme
LEOAPNPK_01158 1.5e-155 L HNH nucleases
LEOAPNPK_01159 2e-137 S Protein of unknown function (DUF805)
LEOAPNPK_01160 2.2e-134 glnQ E ABC transporter, ATP-binding protein
LEOAPNPK_01161 1.3e-290 glnP P ABC transporter permease
LEOAPNPK_01162 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LEOAPNPK_01163 2e-64 yeaO S Protein of unknown function, DUF488
LEOAPNPK_01164 8.2e-124 terC P Integral membrane protein TerC family
LEOAPNPK_01165 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
LEOAPNPK_01166 1e-133 cobB K SIR2 family
LEOAPNPK_01167 4.2e-86
LEOAPNPK_01168 9.3e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEOAPNPK_01169 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
LEOAPNPK_01170 2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEOAPNPK_01171 4.4e-140 ypuA S Protein of unknown function (DUF1002)
LEOAPNPK_01172 2.9e-156 epsV 2.7.8.12 S glycosyl transferase family 2
LEOAPNPK_01173 2.5e-126 S Alpha/beta hydrolase family
LEOAPNPK_01174 1e-53
LEOAPNPK_01175 2.6e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEOAPNPK_01176 3.8e-125 luxT K Bacterial regulatory proteins, tetR family
LEOAPNPK_01177 2.8e-135
LEOAPNPK_01178 1.7e-77 glnPH2 P ABC transporter permease
LEOAPNPK_01179 8.7e-160 glnPH2 P ABC transporter permease
LEOAPNPK_01180 7.1e-79
LEOAPNPK_01181 9.3e-69 S Sel1-like repeats.
LEOAPNPK_01182 3.2e-77 S HIRAN
LEOAPNPK_01183 4.7e-31
LEOAPNPK_01184 2.1e-180
LEOAPNPK_01185 2e-103 3.1.4.37 S AAA domain
LEOAPNPK_01186 9.7e-74 S Sel1-like repeats.
LEOAPNPK_01187 9.3e-63 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
LEOAPNPK_01188 0.0 tetP J Elongation factor G, domain IV
LEOAPNPK_01189 4.6e-23
LEOAPNPK_01190 1.9e-68 S Bacterial mobilisation protein (MobC)
LEOAPNPK_01191 6.7e-12
LEOAPNPK_01192 1.9e-15 D nuclear chromosome segregation
LEOAPNPK_01193 4.9e-52
LEOAPNPK_01196 2.1e-18 S TPM domain
LEOAPNPK_01198 4.8e-42 lemA S LemA family
LEOAPNPK_01200 3.5e-35
LEOAPNPK_01202 2.6e-13 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LEOAPNPK_01203 4.4e-158 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
LEOAPNPK_01204 5.5e-53
LEOAPNPK_01205 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LEOAPNPK_01206 2.8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEOAPNPK_01207 6.2e-168 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEOAPNPK_01208 4.6e-199 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEOAPNPK_01209 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
LEOAPNPK_01210 0.0 FbpA K Fibronectin-binding protein
LEOAPNPK_01211 1.1e-66
LEOAPNPK_01212 3.5e-160 degV S EDD domain protein, DegV family
LEOAPNPK_01213 1.3e-305 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEOAPNPK_01214 1.8e-203 xerS L Belongs to the 'phage' integrase family
LEOAPNPK_01215 4.1e-67
LEOAPNPK_01216 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
LEOAPNPK_01217 1.5e-211 M Glycosyl hydrolases family 25
LEOAPNPK_01218 2e-39 S Transglycosylase associated protein
LEOAPNPK_01219 2.7e-123 yoaK S Protein of unknown function (DUF1275)
LEOAPNPK_01220 3.2e-92 S SNARE associated Golgi protein
LEOAPNPK_01221 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
LEOAPNPK_01222 7.1e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEOAPNPK_01223 1.9e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEOAPNPK_01224 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
LEOAPNPK_01225 8e-111 yjbK S CYTH
LEOAPNPK_01226 1.2e-114 yjbH Q Thioredoxin
LEOAPNPK_01227 5.8e-160 coiA 3.6.4.12 S Competence protein
LEOAPNPK_01228 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LEOAPNPK_01229 6.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEOAPNPK_01230 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEOAPNPK_01231 8.5e-41 ptsH G phosphocarrier protein HPR
LEOAPNPK_01232 5.3e-26
LEOAPNPK_01233 0.0 clpE O Belongs to the ClpA ClpB family
LEOAPNPK_01234 9.6e-43 XK27_09445 S Domain of unknown function (DUF1827)
LEOAPNPK_01235 5.2e-30
LEOAPNPK_01236 6.6e-51 L Transposase
LEOAPNPK_01237 1.8e-16
LEOAPNPK_01238 3.2e-265 V ABC transporter transmembrane region
LEOAPNPK_01239 2.4e-147
LEOAPNPK_01240 3.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LEOAPNPK_01241 1.1e-140 hlyX S Transporter associated domain
LEOAPNPK_01242 1.6e-74
LEOAPNPK_01243 3.5e-85
LEOAPNPK_01244 1.9e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
LEOAPNPK_01245 3.5e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEOAPNPK_01246 7.5e-177 D Alpha beta
LEOAPNPK_01247 9.4e-46
LEOAPNPK_01248 1.9e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
LEOAPNPK_01249 6.3e-216 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LEOAPNPK_01250 1.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
LEOAPNPK_01251 7.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEOAPNPK_01252 4.7e-163 yihY S Belongs to the UPF0761 family
LEOAPNPK_01253 6.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
LEOAPNPK_01254 4.1e-80 fld C Flavodoxin
LEOAPNPK_01255 3.1e-87 gtcA S Teichoic acid glycosylation protein
LEOAPNPK_01256 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LEOAPNPK_01258 6.2e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEOAPNPK_01259 1.2e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
LEOAPNPK_01260 4.7e-131 M Glycosyl hydrolases family 25
LEOAPNPK_01261 9.7e-231 potE E amino acid
LEOAPNPK_01262 0.0 1.3.5.4 C FAD binding domain
LEOAPNPK_01263 4.1e-90 L PFAM transposase, IS4 family protein
LEOAPNPK_01264 0.0 1.3.5.4 C FAD binding domain
LEOAPNPK_01265 3.7e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LEOAPNPK_01266 1.8e-248 yhdP S Transporter associated domain
LEOAPNPK_01267 2.3e-119 C nitroreductase
LEOAPNPK_01268 2.1e-39
LEOAPNPK_01269 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LEOAPNPK_01270 7e-81
LEOAPNPK_01271 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
LEOAPNPK_01272 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
LEOAPNPK_01273 5.7e-149 S hydrolase
LEOAPNPK_01274 5.8e-160 rssA S Phospholipase, patatin family
LEOAPNPK_01275 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
LEOAPNPK_01276 3.3e-138 glcR K DeoR C terminal sensor domain
LEOAPNPK_01277 1e-60 S Enterocin A Immunity
LEOAPNPK_01278 1.2e-154 S hydrolase
LEOAPNPK_01279 1.4e-133 ydhQ K UbiC transcription regulator-associated domain protein
LEOAPNPK_01280 2.8e-176 rihB 3.2.2.1 F Nucleoside
LEOAPNPK_01281 0.0 kup P Transport of potassium into the cell
LEOAPNPK_01282 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LEOAPNPK_01283 1.6e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEOAPNPK_01284 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
LEOAPNPK_01285 2.9e-235 G Bacterial extracellular solute-binding protein
LEOAPNPK_01286 4.9e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
LEOAPNPK_01287 3.3e-86
LEOAPNPK_01288 1.2e-163 S Protein of unknown function (DUF2974)
LEOAPNPK_01289 4.7e-109 glnP P ABC transporter permease
LEOAPNPK_01290 9.7e-91 gluC P ABC transporter permease
LEOAPNPK_01291 2.4e-150 glnH ET ABC transporter substrate-binding protein
LEOAPNPK_01292 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEOAPNPK_01293 3.6e-114 udk 2.7.1.48 F Zeta toxin
LEOAPNPK_01294 3.1e-251 G MFS/sugar transport protein
LEOAPNPK_01295 3.8e-102 S ABC-type cobalt transport system, permease component
LEOAPNPK_01296 0.0 V ABC transporter transmembrane region
LEOAPNPK_01297 6.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
LEOAPNPK_01298 1.4e-80 K Transcriptional regulator, MarR family
LEOAPNPK_01299 2.4e-147 glnH ET ABC transporter
LEOAPNPK_01300 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
LEOAPNPK_01301 3.3e-242 steT E amino acid
LEOAPNPK_01302 3.4e-239 steT E amino acid
LEOAPNPK_01303 5.5e-138
LEOAPNPK_01304 1.3e-173 S Aldo keto reductase
LEOAPNPK_01305 2e-310 ybiT S ABC transporter, ATP-binding protein
LEOAPNPK_01306 6e-210 pepA E M42 glutamyl aminopeptidase
LEOAPNPK_01307 2.6e-103
LEOAPNPK_01308 2.4e-136
LEOAPNPK_01309 5.6e-217 mdtG EGP Major facilitator Superfamily
LEOAPNPK_01310 1.6e-261 emrY EGP Major facilitator Superfamily
LEOAPNPK_01311 4.7e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEOAPNPK_01312 5.8e-239 pyrP F Permease
LEOAPNPK_01313 8e-293 K Putative DNA-binding domain
LEOAPNPK_01314 2.1e-34
LEOAPNPK_01315 4.9e-159 S reductase
LEOAPNPK_01316 1.4e-18
LEOAPNPK_01317 7e-248 EGP Sugar (and other) transporter
LEOAPNPK_01318 1.2e-18
LEOAPNPK_01319 1.9e-211
LEOAPNPK_01320 1.2e-123 S SLAP domain
LEOAPNPK_01321 1.2e-191 S Bacteriocin helveticin-J
LEOAPNPK_01322 1.2e-44
LEOAPNPK_01323 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01324 4e-32 E Zn peptidase
LEOAPNPK_01325 3.3e-286 clcA P chloride
LEOAPNPK_01326 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEOAPNPK_01327 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LEOAPNPK_01328 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEOAPNPK_01329 4.7e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEOAPNPK_01330 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEOAPNPK_01331 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEOAPNPK_01332 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
LEOAPNPK_01333 5.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEOAPNPK_01334 9.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEOAPNPK_01335 2.6e-35 yaaA S S4 domain protein YaaA
LEOAPNPK_01336 6.2e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEOAPNPK_01337 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEOAPNPK_01338 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEOAPNPK_01339 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
LEOAPNPK_01340 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEOAPNPK_01341 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEOAPNPK_01342 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LEOAPNPK_01343 5.7e-69 rplI J Binds to the 23S rRNA
LEOAPNPK_01344 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LEOAPNPK_01345 1e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
LEOAPNPK_01346 1.3e-165 degV S DegV family
LEOAPNPK_01347 3.5e-168 scrK 2.7.1.2, 2.7.1.4 GK ROK family
LEOAPNPK_01349 1.4e-16
LEOAPNPK_01350 2e-230 I Protein of unknown function (DUF2974)
LEOAPNPK_01351 9.8e-121 yhiD S MgtC family
LEOAPNPK_01354 3.4e-178 S Cysteine-rich secretory protein family
LEOAPNPK_01355 1.5e-220 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEOAPNPK_01357 4.9e-41 relB L RelB antitoxin
LEOAPNPK_01358 5.2e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LEOAPNPK_01359 1.2e-139 epsB M biosynthesis protein
LEOAPNPK_01360 6.5e-113 ywqD 2.7.10.1 D Capsular exopolysaccharide family
LEOAPNPK_01361 4.5e-143 ywqE 3.1.3.48 GM PHP domain protein
LEOAPNPK_01362 1.5e-96 rfbP 2.7.8.6 M Bacterial sugar transferase
LEOAPNPK_01363 3.6e-110 cps1D M Domain of unknown function (DUF4422)
LEOAPNPK_01364 8.4e-109 glfT1 1.1.1.133 S Glycosyltransferase like family 2
LEOAPNPK_01365 2.8e-114 M Glycosyltransferase, group 1 family protein
LEOAPNPK_01366 1.9e-105 M Glycosyl transferases group 1
LEOAPNPK_01367 6.3e-91 glfT1 1.1.1.133 S Glycosyltransferase like family 2
LEOAPNPK_01368 2.7e-63 S Psort location CytoplasmicMembrane, score 9.99
LEOAPNPK_01369 5.7e-19 cysE_1 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
LEOAPNPK_01370 9.9e-192 glf 5.4.99.9 M UDP-galactopyranose mutase
LEOAPNPK_01371 1.2e-255 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
LEOAPNPK_01373 8.8e-131 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01374 8.6e-21
LEOAPNPK_01375 9.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEOAPNPK_01376 1.7e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEOAPNPK_01377 6.3e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
LEOAPNPK_01378 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
LEOAPNPK_01379 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEOAPNPK_01380 4.8e-78 S PAS domain
LEOAPNPK_01381 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
LEOAPNPK_01382 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
LEOAPNPK_01383 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
LEOAPNPK_01384 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
LEOAPNPK_01385 4.7e-210 msmX P Belongs to the ABC transporter superfamily
LEOAPNPK_01386 1.3e-213 malE G Bacterial extracellular solute-binding protein
LEOAPNPK_01387 3.1e-248 malF P Binding-protein-dependent transport system inner membrane component
LEOAPNPK_01388 3.3e-147 malG P ABC transporter permease
LEOAPNPK_01389 7.3e-67 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01391 1.6e-28
LEOAPNPK_01392 2.3e-09
LEOAPNPK_01393 3.2e-89 ymdB S Macro domain protein
LEOAPNPK_01394 2.1e-211 mdtG EGP Major facilitator Superfamily
LEOAPNPK_01395 5.1e-176
LEOAPNPK_01396 5.5e-228 L COG3547 Transposase and inactivated derivatives
LEOAPNPK_01397 1e-248 S Uncharacterised protein family (UPF0236)
LEOAPNPK_01399 3.7e-93 D nuclear chromosome segregation
LEOAPNPK_01400 3e-110 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01401 9.6e-93
LEOAPNPK_01402 4.3e-96 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01403 4.4e-68 S Protein of unknown function (DUF3232)
LEOAPNPK_01404 5.3e-134 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01405 4.7e-111
LEOAPNPK_01408 1.7e-201 L COG2826 Transposase and inactivated derivatives, IS30 family
LEOAPNPK_01410 4e-35
LEOAPNPK_01411 2.5e-33 gepA S Protein of unknown function (DUF4065)
LEOAPNPK_01412 3e-147
LEOAPNPK_01413 3e-170
LEOAPNPK_01414 2e-263 glnA 6.3.1.2 E glutamine synthetase
LEOAPNPK_01415 2e-225 ynbB 4.4.1.1 P aluminum resistance
LEOAPNPK_01416 9.2e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEOAPNPK_01417 1.5e-65 yqhL P Rhodanese-like protein
LEOAPNPK_01418 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
LEOAPNPK_01419 3.1e-119 gluP 3.4.21.105 S Rhomboid family
LEOAPNPK_01420 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEOAPNPK_01421 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LEOAPNPK_01422 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
LEOAPNPK_01423 0.0 S membrane
LEOAPNPK_01424 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
LEOAPNPK_01425 1.3e-38 S RelB antitoxin
LEOAPNPK_01426 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
LEOAPNPK_01427 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEOAPNPK_01428 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
LEOAPNPK_01429 1.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEOAPNPK_01430 1.9e-158 isdE P Periplasmic binding protein
LEOAPNPK_01431 5.7e-124 M Iron Transport-associated domain
LEOAPNPK_01432 3e-09 isdH M Iron Transport-associated domain
LEOAPNPK_01433 1.9e-88
LEOAPNPK_01434 1.1e-112 S SLAP domain
LEOAPNPK_01435 1.1e-49 S Uncharacterized protein conserved in bacteria (DUF2263)
LEOAPNPK_01436 4.4e-83 S An automated process has identified a potential problem with this gene model
LEOAPNPK_01437 1.2e-138 S Protein of unknown function (DUF3100)
LEOAPNPK_01438 7.3e-207 3.5.1.47 S Peptidase dimerisation domain
LEOAPNPK_01439 7.3e-233 Q Imidazolonepropionase and related amidohydrolases
LEOAPNPK_01440 0.0 oppA E ABC transporter
LEOAPNPK_01441 2.4e-147 S Sucrose-6F-phosphate phosphohydrolase
LEOAPNPK_01442 0.0 mco Q Multicopper oxidase
LEOAPNPK_01443 5.7e-25
LEOAPNPK_01444 3.2e-158 metQ1 P Belongs to the nlpA lipoprotein family
LEOAPNPK_01445 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
LEOAPNPK_01446 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEOAPNPK_01447 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEOAPNPK_01448 2.7e-199 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEOAPNPK_01449 2.4e-161 cjaA ET ABC transporter substrate-binding protein
LEOAPNPK_01450 9.3e-43 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEOAPNPK_01451 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
LEOAPNPK_01452 0.0 XK27_06780 V ABC transporter permease
LEOAPNPK_01453 9.6e-36
LEOAPNPK_01454 7.9e-291 ytgP S Polysaccharide biosynthesis protein
LEOAPNPK_01455 2.7e-137 lysA2 M Glycosyl hydrolases family 25
LEOAPNPK_01456 7.4e-132 S Protein of unknown function (DUF975)
LEOAPNPK_01457 3.8e-168 pbpX2 V Beta-lactamase
LEOAPNPK_01458 5.2e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LEOAPNPK_01459 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEOAPNPK_01460 1.2e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
LEOAPNPK_01461 2e-288 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEOAPNPK_01462 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
LEOAPNPK_01463 4.7e-48
LEOAPNPK_01464 1.7e-215 ywhK S Membrane
LEOAPNPK_01465 5.1e-81 ykuL S (CBS) domain
LEOAPNPK_01466 0.0 cadA P P-type ATPase
LEOAPNPK_01467 5.7e-62
LEOAPNPK_01468 5.7e-206 napA P Sodium/hydrogen exchanger family
LEOAPNPK_01469 3.8e-188 V ABC transporter transmembrane region
LEOAPNPK_01470 1.4e-39 L Integrase core domain
LEOAPNPK_01471 3.6e-114 K Transcriptional regulator
LEOAPNPK_01472 2.1e-291 M Exporter of polyketide antibiotics
LEOAPNPK_01473 2.6e-166 yjjC V ABC transporter
LEOAPNPK_01474 1.3e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
LEOAPNPK_01475 2.1e-77 L Transposase and inactivated derivatives, IS30 family
LEOAPNPK_01476 1.9e-14
LEOAPNPK_01477 8e-68 C lyase activity
LEOAPNPK_01478 3.4e-184 L Psort location Cytoplasmic, score
LEOAPNPK_01479 1.7e-18
LEOAPNPK_01480 3e-268 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
LEOAPNPK_01481 1.6e-64 V ABC transporter transmembrane region
LEOAPNPK_01482 2.1e-74 S Putative adhesin
LEOAPNPK_01483 2.1e-157 mutR K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01484 1.2e-53
LEOAPNPK_01485 3.2e-154 EGP Major facilitator Superfamily
LEOAPNPK_01486 9.7e-110 ropB K Transcriptional regulator
LEOAPNPK_01487 9.1e-121 S CAAX protease self-immunity
LEOAPNPK_01488 3.6e-194 S DUF218 domain
LEOAPNPK_01489 0.0 macB_3 V ABC transporter, ATP-binding protein
LEOAPNPK_01490 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LEOAPNPK_01491 2.8e-100 S ECF transporter, substrate-specific component
LEOAPNPK_01492 4.7e-202 tcsA S ABC transporter substrate-binding protein PnrA-like
LEOAPNPK_01493 1.5e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
LEOAPNPK_01494 3.4e-283 xylG 3.6.3.17 S ABC transporter
LEOAPNPK_01495 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
LEOAPNPK_01496 5.7e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
LEOAPNPK_01497 1.3e-159 yeaE S Aldo/keto reductase family
LEOAPNPK_01498 5.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEOAPNPK_01499 2.5e-118 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LEOAPNPK_01500 3.6e-128 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LEOAPNPK_01501 3.3e-69
LEOAPNPK_01502 2.4e-139 cof S haloacid dehalogenase-like hydrolase
LEOAPNPK_01503 2.2e-230 pbuG S permease
LEOAPNPK_01504 3.9e-92 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01505 3.7e-79 V ATPases associated with a variety of cellular activities
LEOAPNPK_01506 1.2e-147 S ABC-2 family transporter protein
LEOAPNPK_01507 3.3e-121 K helix_turn_helix, mercury resistance
LEOAPNPK_01508 3e-232 pbuG S permease
LEOAPNPK_01509 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
LEOAPNPK_01510 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
LEOAPNPK_01512 3.6e-42 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
LEOAPNPK_01513 2.8e-12 K Transcriptional regulator
LEOAPNPK_01514 2.3e-60 K Transcriptional regulator
LEOAPNPK_01515 5.3e-226 S cog cog1373
LEOAPNPK_01516 5.4e-127 S haloacid dehalogenase-like hydrolase
LEOAPNPK_01517 1.6e-225 pbuG S permease
LEOAPNPK_01518 3.3e-56 K Helix-turn-helix domain
LEOAPNPK_01519 2.3e-72 S Putative adhesin
LEOAPNPK_01520 5.7e-74 atkY K Penicillinase repressor
LEOAPNPK_01521 4.5e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LEOAPNPK_01522 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LEOAPNPK_01523 0.0 copA 3.6.3.54 P P-type ATPase
LEOAPNPK_01524 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
LEOAPNPK_01525 1.2e-105
LEOAPNPK_01526 1.2e-70 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LEOAPNPK_01527 4.6e-227 N Uncharacterized conserved protein (DUF2075)
LEOAPNPK_01528 6.2e-205 pbpX1 V Beta-lactamase
LEOAPNPK_01529 0.0 L Helicase C-terminal domain protein
LEOAPNPK_01530 7.3e-272 E amino acid
LEOAPNPK_01531 3.4e-157 xth 3.1.11.2 L exodeoxyribonuclease III
LEOAPNPK_01534 6.2e-193 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEOAPNPK_01535 4.8e-151 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
LEOAPNPK_01536 0.0 tetP J elongation factor G
LEOAPNPK_01537 1e-156 yvgN C Aldo keto reductase
LEOAPNPK_01538 5.1e-151 P CorA-like Mg2+ transporter protein
LEOAPNPK_01539 3.5e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LEOAPNPK_01540 6.4e-148 ropB K Helix-turn-helix domain
LEOAPNPK_01541 1.8e-287 V ABC-type multidrug transport system, ATPase and permease components
LEOAPNPK_01542 7.3e-69 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
LEOAPNPK_01543 5.6e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEOAPNPK_01544 3.9e-25
LEOAPNPK_01545 2.8e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
LEOAPNPK_01546 2e-135 ecsA V ABC transporter, ATP-binding protein
LEOAPNPK_01547 2.9e-221 ecsB U ABC transporter
LEOAPNPK_01548 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEOAPNPK_01550 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LEOAPNPK_01551 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEOAPNPK_01552 2.7e-249 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LEOAPNPK_01553 6e-236 mepA V MATE efflux family protein
LEOAPNPK_01554 1.5e-175 S SLAP domain
LEOAPNPK_01555 1.1e-286 M Peptidase family M1 domain
LEOAPNPK_01556 1.2e-193 S Bacteriocin helveticin-J
LEOAPNPK_01557 4.7e-21
LEOAPNPK_01558 5.7e-52 L RelB antitoxin
LEOAPNPK_01559 2e-139 qmcA O prohibitin homologues
LEOAPNPK_01560 8e-16 darA C Flavodoxin
LEOAPNPK_01561 1.6e-65 darA C Flavodoxin
LEOAPNPK_01562 1.2e-171 purD 6.3.4.13 F Belongs to the GARS family
LEOAPNPK_01563 0.0 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
LEOAPNPK_01564 5.7e-288 hsdM 2.1.1.72 V type I restriction-modification system
LEOAPNPK_01565 5.3e-100 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
LEOAPNPK_01568 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEOAPNPK_01569 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEOAPNPK_01570 1.2e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEOAPNPK_01571 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEOAPNPK_01572 2.3e-251 dnaB L Replication initiation and membrane attachment
LEOAPNPK_01573 1.3e-168 dnaI L Primosomal protein DnaI
LEOAPNPK_01574 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEOAPNPK_01575 1.7e-85
LEOAPNPK_01578 5.7e-139 L Belongs to the 'phage' integrase family
LEOAPNPK_01580 1.1e-98
LEOAPNPK_01582 1.7e-06 M LysM domain
LEOAPNPK_01584 4.8e-17 S Pfam:Peptidase_M78
LEOAPNPK_01585 2.7e-29 ansR 3.4.21.88 K sequence-specific DNA binding
LEOAPNPK_01586 2e-22 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01587 1.8e-24 S Domain of unknown function (DUF771)
LEOAPNPK_01588 8.5e-08
LEOAPNPK_01589 2e-08 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01591 1.5e-23
LEOAPNPK_01592 1.1e-39 S Protein of unknown function (DUF1351)
LEOAPNPK_01593 5.9e-38 S ERF superfamily
LEOAPNPK_01594 7.3e-35 K Helix-turn-helix domain
LEOAPNPK_01595 2.1e-14 K transcriptional
LEOAPNPK_01596 8.5e-14
LEOAPNPK_01600 3.7e-08
LEOAPNPK_01601 1.3e-81 C Domain of unknown function (DUF4145)
LEOAPNPK_01605 1.9e-160 S Pfam:Terminase_3C
LEOAPNPK_01606 3.8e-136 S Phage portal protein, SPP1 Gp6-like
LEOAPNPK_01607 1.7e-104 S Phage minor capsid protein 2
LEOAPNPK_01609 7e-22 S Phage minor structural protein GP20
LEOAPNPK_01610 3.2e-70 gpG
LEOAPNPK_01611 1e-24
LEOAPNPK_01612 1.3e-18 S Minor capsid protein
LEOAPNPK_01613 1.8e-23 S Minor capsid protein
LEOAPNPK_01614 3e-13 S Minor capsid protein from bacteriophage
LEOAPNPK_01615 4.4e-42 N domain, Protein
LEOAPNPK_01617 6e-29 S Bacteriophage Gp15 protein
LEOAPNPK_01618 1.2e-95 S peptidoglycan catabolic process
LEOAPNPK_01619 7.1e-20 S Phage tail protein
LEOAPNPK_01620 1.9e-13 S Prophage endopeptidase tail
LEOAPNPK_01622 5.4e-71 S Calcineurin-like phosphoesterase
LEOAPNPK_01628 7.5e-36 S Bacteriophage holin of superfamily 6 (Holin_LLH)
LEOAPNPK_01629 7.8e-107 M hydrolase, family 25
LEOAPNPK_01633 1.3e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
LEOAPNPK_01636 4.6e-219 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEOAPNPK_01637 1.7e-260 qacA EGP Major facilitator Superfamily
LEOAPNPK_01638 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEOAPNPK_01639 3.9e-154 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LEOAPNPK_01640 5.8e-194 S Bacterial protein of unknown function (DUF871)
LEOAPNPK_01641 6.9e-145 ybbH_2 K rpiR family
LEOAPNPK_01642 2.3e-273 cydA 1.10.3.14 C ubiquinol oxidase
LEOAPNPK_01643 3.3e-178 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
LEOAPNPK_01644 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LEOAPNPK_01645 5.4e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LEOAPNPK_01646 3.4e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LEOAPNPK_01647 4.4e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEOAPNPK_01648 5.6e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
LEOAPNPK_01649 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
LEOAPNPK_01650 2.1e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
LEOAPNPK_01651 1.3e-168 K LysR substrate binding domain
LEOAPNPK_01652 4.9e-122 3.6.1.27 I Acid phosphatase homologues
LEOAPNPK_01653 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEOAPNPK_01654 8e-299 ytgP S Polysaccharide biosynthesis protein
LEOAPNPK_01655 1.5e-44 pspC KT PspC domain
LEOAPNPK_01657 1.7e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LEOAPNPK_01658 7.4e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEOAPNPK_01659 3.6e-99 M ErfK YbiS YcfS YnhG
LEOAPNPK_01661 1.5e-106 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEOAPNPK_01662 5.9e-117 S Peptidase family M23
LEOAPNPK_01663 1.8e-80
LEOAPNPK_01664 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
LEOAPNPK_01665 3.9e-34 copZ C Heavy-metal-associated domain
LEOAPNPK_01666 8.5e-96 dps P Belongs to the Dps family
LEOAPNPK_01667 1.8e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
LEOAPNPK_01668 8.6e-98 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
LEOAPNPK_01670 3.6e-47
LEOAPNPK_01671 0.0 cas3 L CRISPR-associated helicase cas3
LEOAPNPK_01672 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
LEOAPNPK_01673 8.8e-110 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
LEOAPNPK_01674 4.9e-199 casC L CT1975-like protein
LEOAPNPK_01675 6.8e-133 casD S CRISPR-associated protein (Cas_Cas5)
LEOAPNPK_01676 1.1e-121 casE S CRISPR_assoc
LEOAPNPK_01677 1.3e-173 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LEOAPNPK_01678 4.4e-166 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
LEOAPNPK_01679 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEOAPNPK_01680 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LEOAPNPK_01681 1.6e-71 yqeY S YqeY-like protein
LEOAPNPK_01682 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
LEOAPNPK_01683 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEOAPNPK_01684 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEOAPNPK_01685 1.1e-136 recO L Involved in DNA repair and RecF pathway recombination
LEOAPNPK_01686 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LEOAPNPK_01687 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LEOAPNPK_01688 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEOAPNPK_01689 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEOAPNPK_01690 2.3e-127 S Peptidase family M23
LEOAPNPK_01691 4.8e-81 mutT 3.6.1.55 F NUDIX domain
LEOAPNPK_01692 1.6e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
LEOAPNPK_01693 6.5e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEOAPNPK_01694 1.4e-239 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LEOAPNPK_01695 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
LEOAPNPK_01696 2.4e-122 skfE V ATPases associated with a variety of cellular activities
LEOAPNPK_01697 1.1e-142
LEOAPNPK_01698 1.7e-137
LEOAPNPK_01699 2.5e-144
LEOAPNPK_01700 3.8e-27
LEOAPNPK_01701 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LEOAPNPK_01702 1.8e-144
LEOAPNPK_01703 4.8e-168
LEOAPNPK_01704 1.7e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
LEOAPNPK_01705 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
LEOAPNPK_01706 8.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LEOAPNPK_01707 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
LEOAPNPK_01708 3.7e-179 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LEOAPNPK_01709 1.3e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
LEOAPNPK_01710 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LEOAPNPK_01711 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LEOAPNPK_01712 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LEOAPNPK_01713 2.4e-89 ypmB S Protein conserved in bacteria
LEOAPNPK_01714 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
LEOAPNPK_01715 1.3e-114 dnaD L DnaD domain protein
LEOAPNPK_01716 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEOAPNPK_01717 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
LEOAPNPK_01718 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEOAPNPK_01719 1e-107 ypsA S Belongs to the UPF0398 family
LEOAPNPK_01720 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEOAPNPK_01721 1.8e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LEOAPNPK_01722 1e-242 cpdA S Calcineurin-like phosphoesterase
LEOAPNPK_01723 3.4e-79
LEOAPNPK_01724 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
LEOAPNPK_01725 1.6e-82 M NlpC/P60 family
LEOAPNPK_01726 3.8e-133 cobQ S glutamine amidotransferase
LEOAPNPK_01728 3.7e-67 L RelB antitoxin
LEOAPNPK_01729 6.5e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
LEOAPNPK_01730 5.9e-47 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
LEOAPNPK_01731 2.5e-158 K Transcriptional regulator, LysR family
LEOAPNPK_01732 1.3e-215 I transferase activity, transferring acyl groups other than amino-acyl groups
LEOAPNPK_01733 2.4e-206 S PFAM Archaeal ATPase
LEOAPNPK_01734 1.9e-168 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEOAPNPK_01735 5.6e-85 S GyrI-like small molecule binding domain
LEOAPNPK_01736 9.9e-208 S PFAM Archaeal ATPase
LEOAPNPK_01737 6.4e-235 L Transposase
LEOAPNPK_01738 7.6e-46
LEOAPNPK_01739 2.6e-37
LEOAPNPK_01740 4.5e-94 3.6.1.55 L NUDIX domain
LEOAPNPK_01741 3e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
LEOAPNPK_01742 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LEOAPNPK_01743 8.8e-16 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
LEOAPNPK_01744 9e-30 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
LEOAPNPK_01745 1.8e-86 dcm 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
LEOAPNPK_01746 2.1e-85 S AAA ATPase domain
LEOAPNPK_01748 7e-21
LEOAPNPK_01749 7.4e-12 S Protein of unknown function (DUF2922)
LEOAPNPK_01751 1.1e-23
LEOAPNPK_01753 5.2e-27
LEOAPNPK_01754 3.5e-48 repA S Replication initiator protein A
LEOAPNPK_01755 2.1e-90 S Lysin motif
LEOAPNPK_01756 2.6e-135 L Replication initiation factor
LEOAPNPK_01757 1.2e-42 L Single-strand binding protein family
LEOAPNPK_01758 3.4e-63 L Phage integrase, N-terminal SAM-like domain
LEOAPNPK_01760 0.0 clpE O AAA domain (Cdc48 subfamily)
LEOAPNPK_01761 3.7e-165 S Alpha/beta hydrolase of unknown function (DUF915)
LEOAPNPK_01762 1.3e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEOAPNPK_01763 1e-24 L Transposase
LEOAPNPK_01764 1.2e-62 L Transposase
LEOAPNPK_01765 3.5e-172 L Bifunctional protein
LEOAPNPK_01766 7.9e-54 L Transposase
LEOAPNPK_01767 1.6e-79 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEOAPNPK_01768 7.1e-89 lacA 2.3.1.79 S Transferase hexapeptide repeat
LEOAPNPK_01769 9.3e-204 pbpX1 V Beta-lactamase
LEOAPNPK_01770 5.1e-100 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
LEOAPNPK_01771 7.5e-95 S ECF-type riboflavin transporter, S component
LEOAPNPK_01772 2e-230 S Putative peptidoglycan binding domain
LEOAPNPK_01773 1.1e-83 K Acetyltransferase (GNAT) domain
LEOAPNPK_01774 1.7e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LEOAPNPK_01775 1.9e-191 yrvN L AAA C-terminal domain
LEOAPNPK_01776 2.8e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEOAPNPK_01777 1.9e-283 treB G phosphotransferase system
LEOAPNPK_01778 8.9e-101 treR K UTRA
LEOAPNPK_01779 1.2e-289 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
LEOAPNPK_01780 1.3e-17
LEOAPNPK_01781 1.5e-239 G Bacterial extracellular solute-binding protein
LEOAPNPK_01782 1.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
LEOAPNPK_01783 3.2e-236 XK27_01810 S Calcineurin-like phosphoesterase
LEOAPNPK_01785 2.1e-95
LEOAPNPK_01786 2e-286 V ABC-type multidrug transport system, ATPase and permease components
LEOAPNPK_01787 6.6e-282 V ABC-type multidrug transport system, ATPase and permease components
LEOAPNPK_01788 1.1e-78 hipB K sequence-specific DNA binding
LEOAPNPK_01789 0.0 L PLD-like domain
LEOAPNPK_01790 1.8e-101 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
LEOAPNPK_01791 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
LEOAPNPK_01792 1.6e-282 thrC 4.2.3.1 E Threonine synthase
LEOAPNPK_01793 2.5e-220 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LEOAPNPK_01794 4.2e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEOAPNPK_01795 1.1e-115
LEOAPNPK_01796 3.9e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEOAPNPK_01797 1.3e-53
LEOAPNPK_01798 7.4e-10 S KAP family P-loop domain
LEOAPNPK_01799 1.8e-51 S Bacteriophage abortive infection AbiH
LEOAPNPK_01800 1.9e-158 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
LEOAPNPK_01801 6.1e-12 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
LEOAPNPK_01802 1.2e-129 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEOAPNPK_01803 2.7e-185 ulaA 2.7.1.194 S PTS system sugar-specific permease component
LEOAPNPK_01804 5.3e-23 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
LEOAPNPK_01805 4.3e-45 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LEOAPNPK_01806 1.8e-62 kdsD 5.3.1.13 M SIS domain
LEOAPNPK_01807 9.1e-87 dapA 4.3.3.7 H Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEOAPNPK_01808 5.2e-68 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
LEOAPNPK_01809 3.3e-70 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LEOAPNPK_01810 3.3e-166 UW LPXTG-motif cell wall anchor domain protein
LEOAPNPK_01811 1.1e-84 L the current gene model (or a revised gene model) may contain a
LEOAPNPK_01812 4.2e-61 V Abi-like protein
LEOAPNPK_01813 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
LEOAPNPK_01814 5.1e-15 N HicA toxin of bacterial toxin-antitoxin,
LEOAPNPK_01815 2.4e-68 S HicB_like antitoxin of bacterial toxin-antitoxin system
LEOAPNPK_01816 2e-42 S RelB antitoxin
LEOAPNPK_01817 9.4e-52
LEOAPNPK_01818 3.9e-37 L Transposase
LEOAPNPK_01819 3.6e-106 tra L Transposase and inactivated derivatives, IS30 family
LEOAPNPK_01820 7.3e-145 E Amino acid permease
LEOAPNPK_01821 5e-218 L Transposase
LEOAPNPK_01822 1e-76 vatD S acetyltransferase'
LEOAPNPK_01823 1e-30
LEOAPNPK_01824 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
LEOAPNPK_01825 1.4e-22 S KAP family P-loop domain
LEOAPNPK_01828 2.2e-146 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEOAPNPK_01829 1.3e-110 L COG2826 Transposase and inactivated derivatives, IS30 family
LEOAPNPK_01830 6.8e-66 L COG2826 Transposase and inactivated derivatives, IS30 family
LEOAPNPK_01831 2e-230 L Transposase
LEOAPNPK_01832 3.5e-09 S Domain of unknown function (DUF3841)
LEOAPNPK_01833 4.2e-151 S Domain of unknown function (DUF3883)
LEOAPNPK_01834 1.4e-114 mrr L restriction endonuclease
LEOAPNPK_01835 1.4e-151 L Belongs to the 'phage' integrase family
LEOAPNPK_01836 8.7e-69 3.1.21.3 V Type I restriction modification DNA specificity domain
LEOAPNPK_01837 2.3e-221 hsdM 2.1.1.72 V type I restriction-modification system
LEOAPNPK_01838 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
LEOAPNPK_01839 7.6e-29 S CAAX amino terminal protease
LEOAPNPK_01841 1.6e-129 L PFAM transposase IS116 IS110 IS902
LEOAPNPK_01842 2.4e-51 S Domain of unknown function DUF1829
LEOAPNPK_01843 5.9e-24
LEOAPNPK_01844 5.8e-188 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
LEOAPNPK_01845 0.0 L AAA domain
LEOAPNPK_01846 2.8e-232 yhaO L Ser Thr phosphatase family protein
LEOAPNPK_01847 7.2e-56 yheA S Belongs to the UPF0342 family
LEOAPNPK_01848 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEOAPNPK_01849 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEOAPNPK_01850 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
LEOAPNPK_01851 2.3e-110 G Phosphoglycerate mutase family
LEOAPNPK_01852 1e-139 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LEOAPNPK_01853 8.4e-179 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEOAPNPK_01854 4.7e-56 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEOAPNPK_01855 7.5e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEOAPNPK_01856 1.3e-54
LEOAPNPK_01857 3.2e-147 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
LEOAPNPK_01858 6.9e-155 yisY 1.11.1.10 S Alpha/beta hydrolase family
LEOAPNPK_01859 3.8e-122 mdcG 2.7.7.66 H Phosphoribosyl-dephospho-CoA transferase MdcG
LEOAPNPK_01860 3.5e-302 mdcD 4.1.1.87 I Malonate decarboxylase gamma subunit (MdcE)
LEOAPNPK_01861 7.1e-52 mdcC C Malonate decarboxylase delta subunit (MdcD)
LEOAPNPK_01862 0.0 mdcA 2.3.1.187 I Malonate decarboxylase, alpha subunit, transporter
LEOAPNPK_01863 2.3e-170 mdcH 2.3.1.39 I Acyl transferase domain
LEOAPNPK_01864 4.5e-177 L COG2826 Transposase and inactivated derivatives, IS30 family
LEOAPNPK_01865 5.9e-180 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEOAPNPK_01866 1.8e-115 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LEOAPNPK_01867 8.2e-165 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEOAPNPK_01868 2.4e-208 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEOAPNPK_01869 3.8e-218 KQ helix_turn_helix, mercury resistance
LEOAPNPK_01870 5.7e-23
LEOAPNPK_01871 2.8e-47 lysM M LysM domain
LEOAPNPK_01872 0.0 pepN 3.4.11.2 E aminopeptidase
LEOAPNPK_01873 1.6e-250 dtpT U amino acid peptide transporter
LEOAPNPK_01874 7.3e-19 S Sugar efflux transporter for intercellular exchange
LEOAPNPK_01875 4.8e-257 L Transposase
LEOAPNPK_01876 1.3e-19
LEOAPNPK_01877 1.9e-20
LEOAPNPK_01878 1.1e-14 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01879 4.8e-27 E Zn peptidase
LEOAPNPK_01880 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
LEOAPNPK_01881 3.4e-96 K Helix-turn-helix XRE-family like proteins
LEOAPNPK_01882 3.4e-24 V ABC transporter transmembrane region
LEOAPNPK_01883 2.7e-263
LEOAPNPK_01884 8.1e-115 glsA 3.5.1.2 E Belongs to the glutaminase family
LEOAPNPK_01885 3.7e-132 3.1.3.48 T Tyrosine phosphatase family
LEOAPNPK_01886 9e-22 S Protein of unknown function (DUF3923)
LEOAPNPK_01887 8.7e-57
LEOAPNPK_01888 9e-47 S MazG-like family
LEOAPNPK_01889 3.7e-19
LEOAPNPK_01890 5.6e-65 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LEOAPNPK_01891 2.8e-117 P ABC transporter permease
LEOAPNPK_01892 4.4e-110 papP P ABC transporter, permease protein
LEOAPNPK_01894 4.5e-58 yodB K Transcriptional regulator, HxlR family
LEOAPNPK_01895 3.3e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEOAPNPK_01896 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LEOAPNPK_01897 7.6e-164 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEOAPNPK_01898 1.6e-85 S Aminoacyl-tRNA editing domain
LEOAPNPK_01899 3.6e-224 S SLAP domain
LEOAPNPK_01900 2.4e-50 S CAAX protease self-immunity
LEOAPNPK_01901 8.5e-17
LEOAPNPK_01902 3.3e-278 arlS 2.7.13.3 T Histidine kinase
LEOAPNPK_01903 1.2e-126 K response regulator
LEOAPNPK_01904 5.5e-98 yceD S Uncharacterized ACR, COG1399
LEOAPNPK_01905 1.2e-216 ylbM S Belongs to the UPF0348 family
LEOAPNPK_01906 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEOAPNPK_01907 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
LEOAPNPK_01908 8.3e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEOAPNPK_01909 1.5e-200 yqeH S Ribosome biogenesis GTPase YqeH
LEOAPNPK_01910 4.2e-84 yqeG S HAD phosphatase, family IIIA
LEOAPNPK_01911 9.2e-201 tnpB L Putative transposase DNA-binding domain
LEOAPNPK_01912 5.6e-154 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LEOAPNPK_01913 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEOAPNPK_01914 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LEOAPNPK_01915 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEOAPNPK_01916 7.1e-106 yyaR K Acetyltransferase (GNAT) domain
LEOAPNPK_01917 3e-123 S domain protein
LEOAPNPK_01918 8.3e-168 V ABC transporter
LEOAPNPK_01919 3.8e-75 S Protein of unknown function (DUF3021)
LEOAPNPK_01920 1.6e-73 K LytTr DNA-binding domain
LEOAPNPK_01921 1.2e-38 hxlR K HxlR-like helix-turn-helix
LEOAPNPK_01922 2.9e-38 S Aldo keto reductase
LEOAPNPK_01923 3.8e-52 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEOAPNPK_01924 1.6e-40 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEOAPNPK_01925 8e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
LEOAPNPK_01926 1.9e-61 L COG2826 Transposase and inactivated derivatives, IS30 family
LEOAPNPK_01927 2.3e-38 C FMN_bind
LEOAPNPK_01928 9e-259 I Protein of unknown function (DUF2974)
LEOAPNPK_01929 2.7e-23
LEOAPNPK_01930 1.3e-93 speG J Acetyltransferase (GNAT) domain
LEOAPNPK_01931 4.8e-49
LEOAPNPK_01932 1.6e-283 V ABC transporter transmembrane region
LEOAPNPK_01933 5.8e-288 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEOAPNPK_01934 1e-229 S Tetratricopeptide repeat protein
LEOAPNPK_01935 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEOAPNPK_01936 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LEOAPNPK_01937 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
LEOAPNPK_01938 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LEOAPNPK_01939 2.7e-18 M Lysin motif
LEOAPNPK_01940 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LEOAPNPK_01941 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEOAPNPK_01942 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEOAPNPK_01943 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEOAPNPK_01944 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEOAPNPK_01945 3.1e-167 xerD D recombinase XerD
LEOAPNPK_01946 1.9e-169 cvfB S S1 domain
LEOAPNPK_01947 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LEOAPNPK_01948 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEOAPNPK_01949 0.0 dnaE 2.7.7.7 L DNA polymerase
LEOAPNPK_01950 2.3e-23 S Protein of unknown function (DUF2929)
LEOAPNPK_01951 2.8e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LEOAPNPK_01952 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LEOAPNPK_01953 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
LEOAPNPK_01954 1.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LEOAPNPK_01955 9.9e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEOAPNPK_01956 1.1e-294 I Acyltransferase
LEOAPNPK_01957 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEOAPNPK_01958 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEOAPNPK_01959 1.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
LEOAPNPK_01960 1.4e-243 yfnA E Amino Acid
LEOAPNPK_01961 1.6e-112 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEOAPNPK_01962 5.2e-150 yxeH S hydrolase
LEOAPNPK_01963 1.4e-19 S reductase
LEOAPNPK_01964 2.8e-63 S reductase
LEOAPNPK_01965 6.1e-45 S reductase
LEOAPNPK_01966 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEOAPNPK_01968 2e-222 patA 2.6.1.1 E Aminotransferase
LEOAPNPK_01969 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LEOAPNPK_01970 6.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
LEOAPNPK_01971 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEOAPNPK_01972 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEOAPNPK_01973 2.9e-60
LEOAPNPK_01974 2.5e-175 prmA J Ribosomal protein L11 methyltransferase
LEOAPNPK_01975 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LEOAPNPK_01976 1.3e-249 yjjP S Putative threonine/serine exporter
LEOAPNPK_01977 6.4e-176 citR K Putative sugar-binding domain
LEOAPNPK_01978 1.3e-51
LEOAPNPK_01979 2.1e-08
LEOAPNPK_01980 2.9e-66 S Domain of unknown function DUF1828
LEOAPNPK_01981 7.4e-95 S UPF0397 protein
LEOAPNPK_01982 0.0 ykoD P ABC transporter, ATP-binding protein
LEOAPNPK_01983 6.8e-145 cbiQ P cobalt transport
LEOAPNPK_01984 1.8e-22
LEOAPNPK_01985 9.3e-72 yeaL S Protein of unknown function (DUF441)
LEOAPNPK_01986 4.9e-290 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
LEOAPNPK_01987 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
LEOAPNPK_01988 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
LEOAPNPK_01989 2.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LEOAPNPK_01990 4.2e-152 ydjP I Alpha/beta hydrolase family
LEOAPNPK_01991 3e-273 P Sodium:sulfate symporter transmembrane region
LEOAPNPK_01992 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
LEOAPNPK_01993 5.7e-255 pepC 3.4.22.40 E Peptidase C1-like family
LEOAPNPK_01994 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LEOAPNPK_01995 1.9e-261 frdC 1.3.5.4 C FAD binding domain
LEOAPNPK_01996 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEOAPNPK_01997 2e-73 metI P ABC transporter permease
LEOAPNPK_01998 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEOAPNPK_01999 2.9e-159 metQ2 P Belongs to the nlpA lipoprotein family
LEOAPNPK_02000 5.8e-177 F DNA/RNA non-specific endonuclease
LEOAPNPK_02001 0.0 aha1 P E1-E2 ATPase
LEOAPNPK_02002 3.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEOAPNPK_02003 1.2e-177 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEOAPNPK_02004 4.8e-252 yifK E Amino acid permease
LEOAPNPK_02005 1.7e-143 V ABC-type multidrug transport system, ATPase and permease components
LEOAPNPK_02006 5.2e-122 V ABC-type multidrug transport system, ATPase and permease components
LEOAPNPK_02007 2.8e-288 P ABC transporter
LEOAPNPK_02008 2e-36
LEOAPNPK_02010 8.3e-122 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
LEOAPNPK_02011 8.5e-87 K GNAT family
LEOAPNPK_02012 5.4e-203 XK27_00915 C Luciferase-like monooxygenase
LEOAPNPK_02013 6e-118 rbtT P Major Facilitator Superfamily
LEOAPNPK_02014 2.6e-08 K Bacterial regulatory helix-turn-helix protein, lysR family
LEOAPNPK_02015 9.6e-08 S Protein of unknown function (DUF3021)
LEOAPNPK_02016 4.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEOAPNPK_02017 0.0 L Plasmid pRiA4b ORF-3-like protein
LEOAPNPK_02018 1.5e-245 brnQ U Component of the transport system for branched-chain amino acids
LEOAPNPK_02019 2.8e-119 3.6.1.55 F NUDIX domain
LEOAPNPK_02020 1.7e-76 ltrA S Bacterial low temperature requirement A protein (LtrA)
LEOAPNPK_02021 2.1e-112 S Protein of unknown function (DUF1211)
LEOAPNPK_02022 5.7e-121 lsa S ABC transporter
LEOAPNPK_02023 4.2e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LEOAPNPK_02024 4e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
LEOAPNPK_02025 5.3e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
LEOAPNPK_02026 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LEOAPNPK_02027 4.6e-76 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
LEOAPNPK_02028 2.2e-12 L Transposase and inactivated derivatives, IS30 family
LEOAPNPK_02029 1.9e-96 L Transposase and inactivated derivatives, IS30 family
LEOAPNPK_02030 4.1e-204 mepA V MATE efflux family protein
LEOAPNPK_02031 4.7e-76 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
LEOAPNPK_02032 6.6e-64 S Putative adhesin
LEOAPNPK_02033 1.1e-99 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LEOAPNPK_02035 9.8e-15 1.3.5.4 C succinate dehydrogenase
LEOAPNPK_02036 1.1e-14 K Acetyltransferase (GNAT) domain
LEOAPNPK_02037 1.3e-84 dps P Belongs to the Dps family
LEOAPNPK_02038 4e-179 MA20_14895 S Conserved hypothetical protein 698
LEOAPNPK_02040 3.9e-192 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LEOAPNPK_02041 6.4e-102 3.6.1.27 I Acid phosphatase homologues
LEOAPNPK_02042 1.3e-148 yitS S Uncharacterised protein, DegV family COG1307
LEOAPNPK_02043 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEOAPNPK_02044 7e-89 S Domain of unknown function (DUF4767)
LEOAPNPK_02045 1.2e-85 C nitroreductase
LEOAPNPK_02046 8.4e-138 ypbG 2.7.1.2 GK ROK family
LEOAPNPK_02047 9.2e-272 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEOAPNPK_02048 3.7e-223 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEOAPNPK_02049 3.8e-120 gmuR K UTRA
LEOAPNPK_02050 4.3e-29 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEOAPNPK_02051 1.4e-239 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEOAPNPK_02052 3.2e-71 S Domain of unknown function (DUF3284)
LEOAPNPK_02053 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
LEOAPNPK_02054 4.5e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
LEOAPNPK_02055 3.7e-128 K UTRA domain
LEOAPNPK_02056 4e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEOAPNPK_02057 2.2e-90 alkD L DNA alkylation repair enzyme
LEOAPNPK_02058 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)