ORF_ID e_value Gene_name EC_number CAZy COGs Description
NIEPNHIF_00001 2.2e-117 M NlpC/P60 family
NIEPNHIF_00002 1.4e-136 M NlpC P60 family protein
NIEPNHIF_00003 2.3e-85 M NlpC/P60 family
NIEPNHIF_00004 9.3e-95 gmk2 2.7.4.8 F Guanylate kinase homologues.
NIEPNHIF_00005 2.3e-42
NIEPNHIF_00006 2.9e-279 S O-antigen ligase like membrane protein
NIEPNHIF_00007 3.3e-112
NIEPNHIF_00008 1.5e-222 tnpB L Putative transposase DNA-binding domain
NIEPNHIF_00009 1.9e-77 nrdI F NrdI Flavodoxin like
NIEPNHIF_00010 9.2e-175 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIEPNHIF_00011 3.6e-75
NIEPNHIF_00012 4.5e-111 yvpB S Peptidase_C39 like family
NIEPNHIF_00013 2.5e-83 S Threonine/Serine exporter, ThrE
NIEPNHIF_00014 4.8e-137 thrE S Putative threonine/serine exporter
NIEPNHIF_00015 6.4e-290 S ABC transporter
NIEPNHIF_00016 2.5e-62
NIEPNHIF_00017 5e-72 rimL J Acetyltransferase (GNAT) domain
NIEPNHIF_00018 9.6e-89
NIEPNHIF_00019 1.9e-124 S Protein of unknown function (DUF554)
NIEPNHIF_00020 1.5e-209 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NIEPNHIF_00021 0.0 pepF E oligoendopeptidase F
NIEPNHIF_00022 7.8e-14 Z012_06740 S Fic/DOC family
NIEPNHIF_00023 4.9e-31
NIEPNHIF_00024 6e-70 doc S Prophage maintenance system killer protein
NIEPNHIF_00025 1.7e-36 2.1.1.14 E methionine synthase, vitamin-B12 independent
NIEPNHIF_00026 2.4e-95 2.1.1.14 E methionine synthase, vitamin-B12 independent
NIEPNHIF_00027 6.1e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NIEPNHIF_00028 4.4e-259 lctP C L-lactate permease
NIEPNHIF_00029 8.5e-129 znuB U ABC 3 transport family
NIEPNHIF_00030 8.8e-116 fhuC P ABC transporter
NIEPNHIF_00031 1.4e-148 psaA P Belongs to the bacterial solute-binding protein 9 family
NIEPNHIF_00032 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
NIEPNHIF_00033 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
NIEPNHIF_00034 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NIEPNHIF_00035 1.8e-136 fruR K DeoR C terminal sensor domain
NIEPNHIF_00036 6.7e-218 natB CP ABC-2 family transporter protein
NIEPNHIF_00037 2.7e-163 natA S ABC transporter, ATP-binding protein
NIEPNHIF_00038 4.9e-29
NIEPNHIF_00040 4.4e-68
NIEPNHIF_00041 1.1e-24
NIEPNHIF_00042 6.9e-30 yozG K Transcriptional regulator
NIEPNHIF_00043 5.9e-38
NIEPNHIF_00044 9.2e-10
NIEPNHIF_00046 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NIEPNHIF_00047 1.2e-271 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
NIEPNHIF_00048 1e-24
NIEPNHIF_00049 1.2e-25
NIEPNHIF_00050 2.5e-33
NIEPNHIF_00051 6.2e-54 S Enterocin A Immunity
NIEPNHIF_00052 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NIEPNHIF_00053 2.1e-304 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIEPNHIF_00054 4.6e-208 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
NIEPNHIF_00055 9.6e-121 K response regulator
NIEPNHIF_00056 3e-39 S HicB family
NIEPNHIF_00057 1.8e-205 L Probable transposase
NIEPNHIF_00059 0.0 V ABC transporter
NIEPNHIF_00060 8.7e-304 V ABC transporter, ATP-binding protein
NIEPNHIF_00061 1.8e-107 XK27_01040 S Protein of unknown function (DUF1129)
NIEPNHIF_00062 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIEPNHIF_00063 2.8e-44 yyzM S Bacterial protein of unknown function (DUF951)
NIEPNHIF_00064 8.5e-154 spo0J K Belongs to the ParB family
NIEPNHIF_00065 3.4e-138 soj D Sporulation initiation inhibitor
NIEPNHIF_00066 5.6e-147 noc K Belongs to the ParB family
NIEPNHIF_00067 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NIEPNHIF_00068 4.3e-52 cvpA S Colicin V production protein
NIEPNHIF_00070 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIEPNHIF_00071 6e-151 3.1.3.48 T Tyrosine phosphatase family
NIEPNHIF_00072 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
NIEPNHIF_00073 7.1e-95 nqr 1.5.1.36 S NADPH-dependent FMN reductase
NIEPNHIF_00074 2.8e-147 L Putative transposase DNA-binding domain
NIEPNHIF_00075 1.5e-64 L Resolvase, N-terminal
NIEPNHIF_00076 6.3e-111 K WHG domain
NIEPNHIF_00077 8e-38
NIEPNHIF_00078 2.8e-276 pipD E Dipeptidase
NIEPNHIF_00079 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NIEPNHIF_00080 4.7e-175 hrtB V ABC transporter permease
NIEPNHIF_00081 6.9e-95 ygfC K Bacterial regulatory proteins, tetR family
NIEPNHIF_00082 6e-111 G phosphoglycerate mutase
NIEPNHIF_00083 4.9e-142 aroD S Alpha/beta hydrolase family
NIEPNHIF_00084 8.4e-142 S Belongs to the UPF0246 family
NIEPNHIF_00085 1.2e-120
NIEPNHIF_00086 8.7e-158 2.7.7.12 C Domain of unknown function (DUF4931)
NIEPNHIF_00087 3.4e-206 S Putative peptidoglycan binding domain
NIEPNHIF_00088 3.4e-15
NIEPNHIF_00089 1.2e-244 L transposase, IS605 OrfB family
NIEPNHIF_00090 5.4e-128 liaI S membrane
NIEPNHIF_00091 3e-78 XK27_02470 K LytTr DNA-binding domain
NIEPNHIF_00092 3.5e-48 repA S Replication initiator protein A
NIEPNHIF_00093 5.2e-27
NIEPNHIF_00095 1.1e-23
NIEPNHIF_00097 7.4e-12 S Protein of unknown function (DUF2922)
NIEPNHIF_00098 7e-21
NIEPNHIF_00100 1.4e-102 L Phage integrase, N-terminal SAM-like domain
NIEPNHIF_00101 1.2e-42 L Single-strand binding protein family
NIEPNHIF_00102 2.6e-135 L Replication initiation factor
NIEPNHIF_00130 1.2e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
NIEPNHIF_00131 2.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
NIEPNHIF_00132 1.5e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIEPNHIF_00133 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIEPNHIF_00134 1.7e-29 secG U Preprotein translocase
NIEPNHIF_00135 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NIEPNHIF_00136 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NIEPNHIF_00137 2e-230 L Transposase
NIEPNHIF_00138 1.5e-46 V ABC-type multidrug transport system, ATPase and permease components
NIEPNHIF_00139 3.4e-09 KLT Protein kinase domain
NIEPNHIF_00140 2.4e-159 V ABC-type multidrug transport system, ATPase and permease components
NIEPNHIF_00141 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIEPNHIF_00142 1.9e-146 tatD L hydrolase, TatD family
NIEPNHIF_00143 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NIEPNHIF_00144 2.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIEPNHIF_00145 1.2e-39 veg S Biofilm formation stimulator VEG
NIEPNHIF_00146 3.8e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NIEPNHIF_00147 2.6e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIEPNHIF_00148 5.3e-80
NIEPNHIF_00149 0.0 S SLAP domain
NIEPNHIF_00150 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIEPNHIF_00151 4.7e-171 2.7.1.2 GK ROK family
NIEPNHIF_00152 5e-44
NIEPNHIF_00153 1.9e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIEPNHIF_00154 1e-66 S Domain of unknown function (DUF1934)
NIEPNHIF_00155 1.7e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NIEPNHIF_00156 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIEPNHIF_00157 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIEPNHIF_00158 9.4e-76 K acetyltransferase
NIEPNHIF_00159 4.4e-285 pipD E Dipeptidase
NIEPNHIF_00160 3.2e-155 msmR K AraC-like ligand binding domain
NIEPNHIF_00161 3.9e-224 pbuX F xanthine permease
NIEPNHIF_00162 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIEPNHIF_00164 8.6e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NIEPNHIF_00165 4.7e-275 D FIVAR domain
NIEPNHIF_00166 6.7e-55 3.2.1.18 GH33 M Rib/alpha-like repeat
NIEPNHIF_00169 7.9e-57 ps115 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_00170 2.7e-19 yjdF S Protein of unknown function (DUF2992)
NIEPNHIF_00171 2.3e-59 hxlR K Transcriptional regulator, HxlR family
NIEPNHIF_00172 1.2e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NIEPNHIF_00173 2.1e-96 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIEPNHIF_00174 1e-95
NIEPNHIF_00175 2.6e-142 yfeO P Voltage gated chloride channel
NIEPNHIF_00176 1.5e-186 5.3.3.2 C FMN-dependent dehydrogenase
NIEPNHIF_00177 3.1e-51
NIEPNHIF_00178 6.7e-41
NIEPNHIF_00179 7.5e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NIEPNHIF_00180 2.3e-298 ybeC E amino acid
NIEPNHIF_00181 1.1e-155 S Sucrose-6F-phosphate phosphohydrolase
NIEPNHIF_00182 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
NIEPNHIF_00183 2.5e-39 rpmE2 J Ribosomal protein L31
NIEPNHIF_00184 1.1e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIEPNHIF_00185 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NIEPNHIF_00186 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIEPNHIF_00187 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIEPNHIF_00188 3.4e-129 S (CBS) domain
NIEPNHIF_00189 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NIEPNHIF_00190 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIEPNHIF_00191 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIEPNHIF_00192 1.6e-33 yabO J S4 domain protein
NIEPNHIF_00193 6.8e-60 divIC D Septum formation initiator
NIEPNHIF_00194 6.3e-63 yabR J S1 RNA binding domain
NIEPNHIF_00195 6.9e-242 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NIEPNHIF_00196 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIEPNHIF_00197 1.1e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NIEPNHIF_00198 2.3e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIEPNHIF_00199 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NIEPNHIF_00201 1.6e-08
NIEPNHIF_00202 1.6e-08
NIEPNHIF_00203 1.6e-08
NIEPNHIF_00205 1.1e-80 yebR 1.8.4.14 T GAF domain-containing protein
NIEPNHIF_00206 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIEPNHIF_00207 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIEPNHIF_00208 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIEPNHIF_00209 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NIEPNHIF_00210 1.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NIEPNHIF_00211 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NIEPNHIF_00212 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NIEPNHIF_00213 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NIEPNHIF_00214 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NIEPNHIF_00215 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
NIEPNHIF_00216 5.3e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NIEPNHIF_00217 1.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NIEPNHIF_00218 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NIEPNHIF_00219 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NIEPNHIF_00220 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NIEPNHIF_00221 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NIEPNHIF_00222 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NIEPNHIF_00223 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NIEPNHIF_00224 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NIEPNHIF_00225 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NIEPNHIF_00226 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NIEPNHIF_00227 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIEPNHIF_00228 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NIEPNHIF_00229 9.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NIEPNHIF_00230 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NIEPNHIF_00231 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NIEPNHIF_00232 2.3e-24 rpmD J Ribosomal protein L30
NIEPNHIF_00233 2.6e-71 rplO J Binds to the 23S rRNA
NIEPNHIF_00234 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NIEPNHIF_00235 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NIEPNHIF_00236 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NIEPNHIF_00237 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NIEPNHIF_00238 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NIEPNHIF_00239 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NIEPNHIF_00240 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIEPNHIF_00241 1.4e-60 rplQ J Ribosomal protein L17
NIEPNHIF_00242 1.1e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIEPNHIF_00243 5.4e-158 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIEPNHIF_00244 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIEPNHIF_00245 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NIEPNHIF_00246 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NIEPNHIF_00247 7.9e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
NIEPNHIF_00248 3.4e-149 M Belongs to the glycosyl hydrolase 28 family
NIEPNHIF_00249 4.6e-79 K Acetyltransferase (GNAT) domain
NIEPNHIF_00250 8.8e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NIEPNHIF_00251 7.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NIEPNHIF_00252 1.1e-133 S membrane transporter protein
NIEPNHIF_00253 5.8e-126 gpmB G Belongs to the phosphoglycerate mutase family
NIEPNHIF_00254 5.1e-162 czcD P cation diffusion facilitator family transporter
NIEPNHIF_00255 1.4e-23
NIEPNHIF_00256 2.9e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIEPNHIF_00257 1.1e-183 S AAA domain
NIEPNHIF_00258 3.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
NIEPNHIF_00259 1.2e-51
NIEPNHIF_00260 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NIEPNHIF_00261 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NIEPNHIF_00262 1.3e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIEPNHIF_00263 1.7e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIEPNHIF_00264 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NIEPNHIF_00265 2.1e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIEPNHIF_00266 4.2e-95 sigH K Belongs to the sigma-70 factor family
NIEPNHIF_00267 1.7e-34
NIEPNHIF_00268 1.3e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NIEPNHIF_00269 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIEPNHIF_00270 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIEPNHIF_00271 1.1e-101 nusG K Participates in transcription elongation, termination and antitermination
NIEPNHIF_00272 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIEPNHIF_00273 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIEPNHIF_00274 7.3e-158 pstS P Phosphate
NIEPNHIF_00275 8.6e-163 pstC P probably responsible for the translocation of the substrate across the membrane
NIEPNHIF_00276 1.2e-155 pstA P Phosphate transport system permease protein PstA
NIEPNHIF_00277 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIEPNHIF_00278 3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIEPNHIF_00279 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
NIEPNHIF_00280 4.2e-60 L An automated process has identified a potential problem with this gene model
NIEPNHIF_00281 1.7e-12 GT2,GT4 M family 8
NIEPNHIF_00282 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIEPNHIF_00283 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIEPNHIF_00284 3.9e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
NIEPNHIF_00285 3.8e-116 rsmC 2.1.1.172 J Methyltransferase
NIEPNHIF_00286 9e-26
NIEPNHIF_00287 1.1e-89 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIEPNHIF_00288 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIEPNHIF_00289 5.7e-106 2.4.1.58 GT8 M family 8
NIEPNHIF_00290 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
NIEPNHIF_00291 2.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NIEPNHIF_00292 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIEPNHIF_00293 1.1e-34 S Protein of unknown function (DUF2508)
NIEPNHIF_00294 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIEPNHIF_00295 8.9e-53 yaaQ S Cyclic-di-AMP receptor
NIEPNHIF_00296 3e-156 holB 2.7.7.7 L DNA polymerase III
NIEPNHIF_00297 1.8e-59 yabA L Involved in initiation control of chromosome replication
NIEPNHIF_00298 7.9e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIEPNHIF_00299 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
NIEPNHIF_00300 2.4e-87 S ECF transporter, substrate-specific component
NIEPNHIF_00301 1.5e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NIEPNHIF_00302 1.6e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NIEPNHIF_00303 2.5e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIEPNHIF_00304 6.3e-232 L COG3547 Transposase and inactivated derivatives
NIEPNHIF_00305 1.7e-42
NIEPNHIF_00306 1.4e-30 L COG2963 Transposase and inactivated derivatives
NIEPNHIF_00307 0.0 uup S ABC transporter, ATP-binding protein
NIEPNHIF_00308 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NIEPNHIF_00309 1e-184 scrR K helix_turn _helix lactose operon repressor
NIEPNHIF_00310 3.1e-294 scrB 3.2.1.26 GH32 G invertase
NIEPNHIF_00311 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
NIEPNHIF_00312 2.3e-181 M CHAP domain
NIEPNHIF_00313 3.5e-75
NIEPNHIF_00314 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NIEPNHIF_00315 2.6e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIEPNHIF_00316 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NIEPNHIF_00317 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIEPNHIF_00318 4.5e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIEPNHIF_00319 6.7e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIEPNHIF_00320 9.6e-41 yajC U Preprotein translocase
NIEPNHIF_00321 5.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NIEPNHIF_00322 5.9e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIEPNHIF_00323 6.7e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NIEPNHIF_00324 1.4e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NIEPNHIF_00325 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIEPNHIF_00326 2e-42 yrzL S Belongs to the UPF0297 family
NIEPNHIF_00327 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIEPNHIF_00328 1.1e-50 yrzB S Belongs to the UPF0473 family
NIEPNHIF_00329 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NIEPNHIF_00330 3.5e-54 trxA O Belongs to the thioredoxin family
NIEPNHIF_00331 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIEPNHIF_00332 1.1e-71 yslB S Protein of unknown function (DUF2507)
NIEPNHIF_00333 1.7e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NIEPNHIF_00334 9.6e-112 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NIEPNHIF_00335 2.8e-146 ykuT M mechanosensitive ion channel
NIEPNHIF_00336 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NIEPNHIF_00337 1.3e-36
NIEPNHIF_00338 9.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NIEPNHIF_00339 4.9e-182 ccpA K catabolite control protein A
NIEPNHIF_00340 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NIEPNHIF_00341 4.3e-55
NIEPNHIF_00342 1.5e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NIEPNHIF_00343 1.7e-105 yutD S Protein of unknown function (DUF1027)
NIEPNHIF_00344 4.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NIEPNHIF_00345 3.1e-99 S Protein of unknown function (DUF1461)
NIEPNHIF_00346 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NIEPNHIF_00347 7.7e-103 S TPM domain
NIEPNHIF_00348 6.1e-90 comEB 3.5.4.12 F MafB19-like deaminase
NIEPNHIF_00349 1.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIEPNHIF_00350 1.2e-111 E Belongs to the SOS response-associated peptidase family
NIEPNHIF_00352 7.9e-112
NIEPNHIF_00353 2.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIEPNHIF_00354 2.6e-68 hsp O Belongs to the small heat shock protein (HSP20) family
NIEPNHIF_00355 1.4e-256 pepC 3.4.22.40 E aminopeptidase
NIEPNHIF_00356 1.9e-175 oppF P Belongs to the ABC transporter superfamily
NIEPNHIF_00357 4.2e-200 oppD P Belongs to the ABC transporter superfamily
NIEPNHIF_00358 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIEPNHIF_00359 1.4e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIEPNHIF_00360 1.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIEPNHIF_00361 9.9e-310 oppA E ABC transporter, substratebinding protein
NIEPNHIF_00363 1.2e-123 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIEPNHIF_00364 1.6e-257 pepC 3.4.22.40 E aminopeptidase
NIEPNHIF_00366 3.1e-54
NIEPNHIF_00367 2.4e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIEPNHIF_00368 0.0 XK27_08315 M Sulfatase
NIEPNHIF_00369 7.3e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NIEPNHIF_00370 2.1e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NIEPNHIF_00371 1.4e-98 G Aldose 1-epimerase
NIEPNHIF_00372 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIEPNHIF_00373 2.3e-136
NIEPNHIF_00374 9.5e-144
NIEPNHIF_00375 2.2e-179 S Oxidoreductase family, NAD-binding Rossmann fold
NIEPNHIF_00376 3.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NIEPNHIF_00377 0.0 yjbQ P TrkA C-terminal domain protein
NIEPNHIF_00378 3.3e-208 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NIEPNHIF_00379 1.9e-212 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NIEPNHIF_00380 2.4e-43 L transposase activity
NIEPNHIF_00381 5.2e-97 cadD P Cadmium resistance transporter
NIEPNHIF_00383 6e-34 L Type III restriction enzyme, res subunit
NIEPNHIF_00385 0.0 copB 3.6.3.4 P P-type ATPase
NIEPNHIF_00386 3.9e-72 K Copper transport repressor CopY TcrY
NIEPNHIF_00388 8.8e-81 L transposase, IS605 OrfB family
NIEPNHIF_00389 8.9e-123 S SLAP domain
NIEPNHIF_00390 1.9e-20 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NIEPNHIF_00391 1.9e-158 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NIEPNHIF_00392 1.8e-51 S Bacteriophage abortive infection AbiH
NIEPNHIF_00393 7.4e-10 S KAP family P-loop domain
NIEPNHIF_00394 9.4e-52
NIEPNHIF_00395 2e-42 S RelB antitoxin
NIEPNHIF_00396 2.4e-68 S HicB_like antitoxin of bacterial toxin-antitoxin system
NIEPNHIF_00397 5.1e-15 N HicA toxin of bacterial toxin-antitoxin,
NIEPNHIF_00398 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NIEPNHIF_00399 4.2e-61 V Abi-like protein
NIEPNHIF_00400 1.1e-84 L the current gene model (or a revised gene model) may contain a
NIEPNHIF_00401 1.6e-79 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIEPNHIF_00402 7.1e-89 lacA 2.3.1.79 S Transferase hexapeptide repeat
NIEPNHIF_00403 9.3e-204 pbpX1 V Beta-lactamase
NIEPNHIF_00404 5.1e-100 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NIEPNHIF_00405 7.5e-95 S ECF-type riboflavin transporter, S component
NIEPNHIF_00406 2e-230 S Putative peptidoglycan binding domain
NIEPNHIF_00407 1.1e-83 K Acetyltransferase (GNAT) domain
NIEPNHIF_00408 1.7e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NIEPNHIF_00409 1.9e-191 yrvN L AAA C-terminal domain
NIEPNHIF_00410 2.8e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NIEPNHIF_00411 1.9e-283 treB G phosphotransferase system
NIEPNHIF_00412 8.9e-101 treR K UTRA
NIEPNHIF_00413 1.2e-289 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NIEPNHIF_00414 1.3e-17
NIEPNHIF_00415 1.5e-239 G Bacterial extracellular solute-binding protein
NIEPNHIF_00416 1.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
NIEPNHIF_00417 3.2e-236 XK27_01810 S Calcineurin-like phosphoesterase
NIEPNHIF_00419 4.8e-119 ropB K Helix-turn-helix domain
NIEPNHIF_00421 9.2e-56 S protein encoded in hypervariable junctions of pilus gene clusters
NIEPNHIF_00422 1.2e-36 hicA S HicA toxin of bacterial toxin-antitoxin,
NIEPNHIF_00423 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIEPNHIF_00424 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIEPNHIF_00425 2e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIEPNHIF_00428 6.7e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
NIEPNHIF_00429 3.8e-190 asnA 6.3.1.1 F aspartate--ammonia ligase
NIEPNHIF_00430 7.2e-232 steT_1 E amino acid
NIEPNHIF_00431 1.2e-140 puuD S peptidase C26
NIEPNHIF_00432 5.8e-176 S PFAM Archaeal ATPase
NIEPNHIF_00433 2.4e-248 yifK E Amino acid permease
NIEPNHIF_00434 3.7e-180 cycA E Amino acid permease
NIEPNHIF_00435 3.3e-40 cycA E Amino acid permease
NIEPNHIF_00436 4.7e-114 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NIEPNHIF_00437 3.5e-118 V ABC transporter transmembrane region
NIEPNHIF_00438 4e-57 K Helix-turn-helix domain
NIEPNHIF_00439 1.1e-112 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIEPNHIF_00440 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
NIEPNHIF_00441 2.1e-182 K Transcriptional regulator
NIEPNHIF_00442 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIEPNHIF_00443 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIEPNHIF_00444 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NIEPNHIF_00445 0.0 snf 2.7.11.1 KL domain protein
NIEPNHIF_00446 6.2e-35
NIEPNHIF_00448 1.3e-104 pncA Q Isochorismatase family
NIEPNHIF_00449 1.3e-118
NIEPNHIF_00452 3.6e-63
NIEPNHIF_00453 3.4e-33
NIEPNHIF_00454 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
NIEPNHIF_00455 3.4e-79
NIEPNHIF_00456 1e-242 cpdA S Calcineurin-like phosphoesterase
NIEPNHIF_00457 1.8e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NIEPNHIF_00458 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NIEPNHIF_00459 1e-107 ypsA S Belongs to the UPF0398 family
NIEPNHIF_00460 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NIEPNHIF_00461 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NIEPNHIF_00462 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIEPNHIF_00463 1.3e-114 dnaD L DnaD domain protein
NIEPNHIF_00464 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NIEPNHIF_00465 2.4e-89 ypmB S Protein conserved in bacteria
NIEPNHIF_00466 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NIEPNHIF_00467 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NIEPNHIF_00468 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NIEPNHIF_00469 1.3e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
NIEPNHIF_00470 3.7e-179 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NIEPNHIF_00471 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NIEPNHIF_00472 8.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NIEPNHIF_00473 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
NIEPNHIF_00474 1.7e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
NIEPNHIF_00475 4.8e-168
NIEPNHIF_00476 1.8e-144
NIEPNHIF_00477 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NIEPNHIF_00478 3.8e-27
NIEPNHIF_00479 2.5e-144
NIEPNHIF_00480 1.7e-137
NIEPNHIF_00481 1.1e-142
NIEPNHIF_00482 2.4e-122 skfE V ATPases associated with a variety of cellular activities
NIEPNHIF_00483 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
NIEPNHIF_00484 1.4e-239 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NIEPNHIF_00485 6.5e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIEPNHIF_00486 1.6e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NIEPNHIF_00487 4.8e-81 mutT 3.6.1.55 F NUDIX domain
NIEPNHIF_00488 2.3e-127 S Peptidase family M23
NIEPNHIF_00489 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIEPNHIF_00490 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NIEPNHIF_00491 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NIEPNHIF_00492 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NIEPNHIF_00493 1.1e-136 recO L Involved in DNA repair and RecF pathway recombination
NIEPNHIF_00494 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIEPNHIF_00495 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NIEPNHIF_00496 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
NIEPNHIF_00497 1.6e-71 yqeY S YqeY-like protein
NIEPNHIF_00498 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NIEPNHIF_00499 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NIEPNHIF_00500 4.4e-166 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
NIEPNHIF_00501 1.3e-173 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NIEPNHIF_00502 1.1e-121 casE S CRISPR_assoc
NIEPNHIF_00503 6.8e-133 casD S CRISPR-associated protein (Cas_Cas5)
NIEPNHIF_00504 4.9e-199 casC L CT1975-like protein
NIEPNHIF_00505 8.8e-110 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
NIEPNHIF_00506 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
NIEPNHIF_00507 0.0 cas3 L CRISPR-associated helicase cas3
NIEPNHIF_00508 3.6e-47
NIEPNHIF_00510 8.6e-98 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIEPNHIF_00511 1.8e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NIEPNHIF_00512 8.5e-96 dps P Belongs to the Dps family
NIEPNHIF_00513 3.9e-34 copZ C Heavy-metal-associated domain
NIEPNHIF_00514 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NIEPNHIF_00515 1.8e-80
NIEPNHIF_00516 5.9e-117 S Peptidase family M23
NIEPNHIF_00517 1.5e-106 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIEPNHIF_00519 1.6e-129 L PFAM transposase IS116 IS110 IS902
NIEPNHIF_00520 2.7e-23
NIEPNHIF_00521 1.3e-93 speG J Acetyltransferase (GNAT) domain
NIEPNHIF_00522 4.8e-49
NIEPNHIF_00523 1.6e-283 V ABC transporter transmembrane region
NIEPNHIF_00524 5.8e-288 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIEPNHIF_00525 1e-229 S Tetratricopeptide repeat protein
NIEPNHIF_00526 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NIEPNHIF_00527 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NIEPNHIF_00528 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
NIEPNHIF_00529 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NIEPNHIF_00530 2.7e-18 M Lysin motif
NIEPNHIF_00531 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIEPNHIF_00532 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NIEPNHIF_00533 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIEPNHIF_00534 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIEPNHIF_00535 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIEPNHIF_00536 3.1e-167 xerD D recombinase XerD
NIEPNHIF_00537 1.9e-169 cvfB S S1 domain
NIEPNHIF_00538 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NIEPNHIF_00539 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NIEPNHIF_00540 0.0 dnaE 2.7.7.7 L DNA polymerase
NIEPNHIF_00541 2.3e-23 S Protein of unknown function (DUF2929)
NIEPNHIF_00542 2.8e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NIEPNHIF_00543 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NIEPNHIF_00544 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
NIEPNHIF_00545 1.6e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIEPNHIF_00546 9.9e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NIEPNHIF_00547 1.1e-294 I Acyltransferase
NIEPNHIF_00548 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIEPNHIF_00549 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIEPNHIF_00550 1.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
NIEPNHIF_00551 1.4e-243 yfnA E Amino Acid
NIEPNHIF_00552 1.6e-112 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIEPNHIF_00553 5.2e-150 yxeH S hydrolase
NIEPNHIF_00554 1.4e-19 S reductase
NIEPNHIF_00555 2.8e-63 S reductase
NIEPNHIF_00556 6.1e-45 S reductase
NIEPNHIF_00557 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIEPNHIF_00559 2e-222 patA 2.6.1.1 E Aminotransferase
NIEPNHIF_00560 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NIEPNHIF_00561 6.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NIEPNHIF_00562 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIEPNHIF_00563 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIEPNHIF_00564 2.9e-60
NIEPNHIF_00565 2.5e-175 prmA J Ribosomal protein L11 methyltransferase
NIEPNHIF_00566 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIEPNHIF_00567 1.3e-249 yjjP S Putative threonine/serine exporter
NIEPNHIF_00568 6.4e-176 citR K Putative sugar-binding domain
NIEPNHIF_00569 1.3e-51
NIEPNHIF_00570 2.1e-08
NIEPNHIF_00571 2.9e-66 S Domain of unknown function DUF1828
NIEPNHIF_00572 7.4e-95 S UPF0397 protein
NIEPNHIF_00573 0.0 ykoD P ABC transporter, ATP-binding protein
NIEPNHIF_00574 6.8e-145 cbiQ P cobalt transport
NIEPNHIF_00575 1.8e-22
NIEPNHIF_00576 9.3e-72 yeaL S Protein of unknown function (DUF441)
NIEPNHIF_00577 4.9e-290 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NIEPNHIF_00578 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NIEPNHIF_00579 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
NIEPNHIF_00580 2.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NIEPNHIF_00581 4.2e-152 ydjP I Alpha/beta hydrolase family
NIEPNHIF_00582 3e-273 P Sodium:sulfate symporter transmembrane region
NIEPNHIF_00583 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
NIEPNHIF_00584 5.7e-255 pepC 3.4.22.40 E Peptidase C1-like family
NIEPNHIF_00585 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NIEPNHIF_00586 1.9e-261 frdC 1.3.5.4 C FAD binding domain
NIEPNHIF_00587 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NIEPNHIF_00588 2e-73 metI P ABC transporter permease
NIEPNHIF_00589 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIEPNHIF_00590 2.9e-159 metQ2 P Belongs to the nlpA lipoprotein family
NIEPNHIF_00591 5.8e-177 F DNA/RNA non-specific endonuclease
NIEPNHIF_00592 0.0 aha1 P E1-E2 ATPase
NIEPNHIF_00593 3.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIEPNHIF_00594 1.2e-177 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NIEPNHIF_00595 4.8e-252 yifK E Amino acid permease
NIEPNHIF_00596 1.7e-143 V ABC-type multidrug transport system, ATPase and permease components
NIEPNHIF_00597 5.2e-122 V ABC-type multidrug transport system, ATPase and permease components
NIEPNHIF_00598 2.8e-288 P ABC transporter
NIEPNHIF_00599 2e-36
NIEPNHIF_00601 8.3e-122 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NIEPNHIF_00602 8.5e-87 K GNAT family
NIEPNHIF_00603 5.4e-203 XK27_00915 C Luciferase-like monooxygenase
NIEPNHIF_00604 6e-118 rbtT P Major Facilitator Superfamily
NIEPNHIF_00605 2.6e-08 K Bacterial regulatory helix-turn-helix protein, lysR family
NIEPNHIF_00606 9.6e-08 S Protein of unknown function (DUF3021)
NIEPNHIF_00607 4.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NIEPNHIF_00608 0.0 L Plasmid pRiA4b ORF-3-like protein
NIEPNHIF_00609 1.5e-245 brnQ U Component of the transport system for branched-chain amino acids
NIEPNHIF_00610 2.8e-119 3.6.1.55 F NUDIX domain
NIEPNHIF_00611 1.7e-76 ltrA S Bacterial low temperature requirement A protein (LtrA)
NIEPNHIF_00612 2.1e-112 S Protein of unknown function (DUF1211)
NIEPNHIF_00613 5.7e-121 lsa S ABC transporter
NIEPNHIF_00614 4.2e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIEPNHIF_00615 4e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NIEPNHIF_00616 5.3e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NIEPNHIF_00617 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NIEPNHIF_00618 4.6e-76 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NIEPNHIF_00619 2.2e-12 L Transposase and inactivated derivatives, IS30 family
NIEPNHIF_00620 1.9e-96 L Transposase and inactivated derivatives, IS30 family
NIEPNHIF_00621 4.1e-204 mepA V MATE efflux family protein
NIEPNHIF_00622 4.7e-76 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
NIEPNHIF_00623 6.6e-64 S Putative adhesin
NIEPNHIF_00624 1.1e-99 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NIEPNHIF_00626 9.8e-15 1.3.5.4 C succinate dehydrogenase
NIEPNHIF_00627 1.1e-14 K Acetyltransferase (GNAT) domain
NIEPNHIF_00628 1.3e-84 dps P Belongs to the Dps family
NIEPNHIF_00629 4e-179 MA20_14895 S Conserved hypothetical protein 698
NIEPNHIF_00631 3.9e-192 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIEPNHIF_00632 6.4e-102 3.6.1.27 I Acid phosphatase homologues
NIEPNHIF_00633 1.3e-148 yitS S Uncharacterised protein, DegV family COG1307
NIEPNHIF_00634 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIEPNHIF_00635 7e-89 S Domain of unknown function (DUF4767)
NIEPNHIF_00636 1.2e-85 C nitroreductase
NIEPNHIF_00637 8.4e-138 ypbG 2.7.1.2 GK ROK family
NIEPNHIF_00638 9.2e-272 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIEPNHIF_00639 3.7e-223 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEPNHIF_00640 3.8e-120 gmuR K UTRA
NIEPNHIF_00641 4.3e-29 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIEPNHIF_00642 1.4e-239 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIEPNHIF_00643 3.2e-71 S Domain of unknown function (DUF3284)
NIEPNHIF_00644 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
NIEPNHIF_00645 4.5e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NIEPNHIF_00646 3.7e-128 K UTRA domain
NIEPNHIF_00647 4e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIEPNHIF_00648 2.2e-90 alkD L DNA alkylation repair enzyme
NIEPNHIF_00649 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
NIEPNHIF_00650 6.2e-58
NIEPNHIF_00651 8.7e-160 glnPH2 P ABC transporter permease
NIEPNHIF_00652 1.7e-77 glnPH2 P ABC transporter permease
NIEPNHIF_00653 2.8e-135
NIEPNHIF_00654 3.8e-125 luxT K Bacterial regulatory proteins, tetR family
NIEPNHIF_00655 2.6e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIEPNHIF_00656 1e-53
NIEPNHIF_00657 2.5e-126 S Alpha/beta hydrolase family
NIEPNHIF_00658 2.9e-156 epsV 2.7.8.12 S glycosyl transferase family 2
NIEPNHIF_00659 4.4e-140 ypuA S Protein of unknown function (DUF1002)
NIEPNHIF_00660 2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIEPNHIF_00661 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
NIEPNHIF_00662 9.3e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIEPNHIF_00663 4.2e-86
NIEPNHIF_00664 1e-133 cobB K SIR2 family
NIEPNHIF_00665 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
NIEPNHIF_00666 8.2e-124 terC P Integral membrane protein TerC family
NIEPNHIF_00667 2e-64 yeaO S Protein of unknown function, DUF488
NIEPNHIF_00668 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NIEPNHIF_00669 1.3e-290 glnP P ABC transporter permease
NIEPNHIF_00670 2.2e-134 glnQ E ABC transporter, ATP-binding protein
NIEPNHIF_00671 2e-137 S Protein of unknown function (DUF805)
NIEPNHIF_00672 1.5e-155 L HNH nucleases
NIEPNHIF_00673 1.4e-121 yfbR S HD containing hydrolase-like enzyme
NIEPNHIF_00674 5.2e-177 G Glycosyl hydrolases family 8
NIEPNHIF_00675 5.2e-216 ydaM M Glycosyl transferase
NIEPNHIF_00677 2.6e-115
NIEPNHIF_00678 1.2e-17
NIEPNHIF_00679 6.9e-190 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NIEPNHIF_00680 6.2e-84 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NIEPNHIF_00681 2e-70 S Iron-sulphur cluster biosynthesis
NIEPNHIF_00682 4e-193 ybiR P Citrate transporter
NIEPNHIF_00683 1e-96 lemA S LemA family
NIEPNHIF_00684 6.6e-162 htpX O Belongs to the peptidase M48B family
NIEPNHIF_00685 7.9e-174 K helix_turn_helix, arabinose operon control protein
NIEPNHIF_00686 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
NIEPNHIF_00687 1.1e-76 P Cobalt transport protein
NIEPNHIF_00688 6e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
NIEPNHIF_00689 2.8e-99 G Peptidase_C39 like family
NIEPNHIF_00690 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIEPNHIF_00691 3.3e-151 htrA 3.4.21.107 O serine protease
NIEPNHIF_00692 8.2e-148 vicX 3.1.26.11 S domain protein
NIEPNHIF_00693 3.4e-149 yycI S YycH protein
NIEPNHIF_00694 3.7e-257 yycH S YycH protein
NIEPNHIF_00695 3.8e-305 vicK 2.7.13.3 T Histidine kinase
NIEPNHIF_00696 4.8e-131 K response regulator
NIEPNHIF_00698 4.9e-34
NIEPNHIF_00700 3.2e-149 arbV 2.3.1.51 I Acyl-transferase
NIEPNHIF_00701 1.2e-157 arbx M Glycosyl transferase family 8
NIEPNHIF_00702 4.5e-185 arbY M Glycosyl transferase family 8
NIEPNHIF_00703 6e-182 arbY M Glycosyl transferase family 8
NIEPNHIF_00704 4.6e-168 arbZ I Phosphate acyltransferases
NIEPNHIF_00705 1.4e-36 S Cytochrome B5
NIEPNHIF_00706 3.6e-81 XK27_04435 3.5.4.5 J FR47-like protein
NIEPNHIF_00708 8.8e-131 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_00709 8.6e-21
NIEPNHIF_00710 9.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NIEPNHIF_00711 1.7e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIEPNHIF_00712 6.3e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
NIEPNHIF_00713 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
NIEPNHIF_00714 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIEPNHIF_00715 4.8e-78 S PAS domain
NIEPNHIF_00716 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
NIEPNHIF_00717 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NIEPNHIF_00718 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NIEPNHIF_00719 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NIEPNHIF_00720 4.7e-210 msmX P Belongs to the ABC transporter superfamily
NIEPNHIF_00721 1.3e-213 malE G Bacterial extracellular solute-binding protein
NIEPNHIF_00722 3.1e-248 malF P Binding-protein-dependent transport system inner membrane component
NIEPNHIF_00723 3.3e-147 malG P ABC transporter permease
NIEPNHIF_00724 7.3e-67 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_00726 1.6e-28
NIEPNHIF_00727 2.3e-09
NIEPNHIF_00728 3.2e-89 ymdB S Macro domain protein
NIEPNHIF_00729 2.1e-211 mdtG EGP Major facilitator Superfamily
NIEPNHIF_00730 5.1e-176
NIEPNHIF_00731 5.5e-228 L COG3547 Transposase and inactivated derivatives
NIEPNHIF_00732 3.8e-196 pbpX1 V Beta-lactamase
NIEPNHIF_00733 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIEPNHIF_00734 1.4e-217 aspC 2.6.1.1 E Aminotransferase
NIEPNHIF_00735 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIEPNHIF_00736 4.4e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIEPNHIF_00737 1.1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NIEPNHIF_00738 9.7e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NIEPNHIF_00739 5.1e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIEPNHIF_00740 6.7e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NIEPNHIF_00741 1.5e-191 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NIEPNHIF_00742 2.7e-103 yjeM E Amino acid permease
NIEPNHIF_00743 1.3e-22 yjeM E Amino Acid
NIEPNHIF_00744 3.7e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
NIEPNHIF_00745 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIEPNHIF_00746 4e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIEPNHIF_00747 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NIEPNHIF_00748 8.3e-151
NIEPNHIF_00749 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIEPNHIF_00750 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIEPNHIF_00751 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
NIEPNHIF_00752 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
NIEPNHIF_00753 0.0 comEC S Competence protein ComEC
NIEPNHIF_00754 6.5e-77 comEA L Competence protein ComEA
NIEPNHIF_00755 3.3e-189 ylbL T Belongs to the peptidase S16 family
NIEPNHIF_00756 1.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIEPNHIF_00757 1.7e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NIEPNHIF_00758 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NIEPNHIF_00759 2.7e-211 ftsW D Belongs to the SEDS family
NIEPNHIF_00760 0.0 typA T GTP-binding protein TypA
NIEPNHIF_00761 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIEPNHIF_00762 3.2e-33 ykzG S Belongs to the UPF0356 family
NIEPNHIF_00763 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIEPNHIF_00764 1.8e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NIEPNHIF_00765 7e-295 L Nuclease-related domain
NIEPNHIF_00766 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NIEPNHIF_00767 5.4e-105 S Repeat protein
NIEPNHIF_00768 1.5e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NIEPNHIF_00769 4.6e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NIEPNHIF_00770 2.2e-57 XK27_04120 S Putative amino acid metabolism
NIEPNHIF_00771 2.7e-216 iscS 2.8.1.7 E Aminotransferase class V
NIEPNHIF_00772 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIEPNHIF_00773 2.1e-38
NIEPNHIF_00774 9.8e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NIEPNHIF_00775 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
NIEPNHIF_00776 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIEPNHIF_00777 2.8e-74 gpsB D DivIVA domain protein
NIEPNHIF_00778 7.4e-149 ylmH S S4 domain protein
NIEPNHIF_00779 1.7e-45 yggT S YGGT family
NIEPNHIF_00780 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIEPNHIF_00781 5.5e-205 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIEPNHIF_00782 1.3e-243 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NIEPNHIF_00783 1.2e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NIEPNHIF_00784 4.4e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIEPNHIF_00785 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIEPNHIF_00786 1.1e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIEPNHIF_00787 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NIEPNHIF_00788 4.1e-54 ftsL D Cell division protein FtsL
NIEPNHIF_00789 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIEPNHIF_00790 6.3e-78 mraZ K Belongs to the MraZ family
NIEPNHIF_00791 6.4e-54 S Protein of unknown function (DUF3397)
NIEPNHIF_00793 1.2e-94 mreD
NIEPNHIF_00794 6.7e-148 mreC M Involved in formation and maintenance of cell shape
NIEPNHIF_00795 1.8e-176 mreB D cell shape determining protein MreB
NIEPNHIF_00796 2.3e-108 radC L DNA repair protein
NIEPNHIF_00797 7.5e-126 S Haloacid dehalogenase-like hydrolase
NIEPNHIF_00798 1e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NIEPNHIF_00799 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIEPNHIF_00800 1.3e-51
NIEPNHIF_00801 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
NIEPNHIF_00802 0.0 3.6.3.8 P P-type ATPase
NIEPNHIF_00804 2.9e-44
NIEPNHIF_00805 1.5e-94 S Protein of unknown function (DUF3990)
NIEPNHIF_00806 4.7e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NIEPNHIF_00807 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
NIEPNHIF_00808 9.1e-28 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NIEPNHIF_00809 1.9e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NIEPNHIF_00810 4.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NIEPNHIF_00811 1.1e-247 L Transposase
NIEPNHIF_00813 3.7e-93 D nuclear chromosome segregation
NIEPNHIF_00814 3e-110 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_00815 9.6e-93
NIEPNHIF_00816 4.3e-96 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_00817 4.4e-68 S Protein of unknown function (DUF3232)
NIEPNHIF_00818 5.3e-134 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_00819 4.7e-111
NIEPNHIF_00822 1.7e-201 L COG2826 Transposase and inactivated derivatives, IS30 family
NIEPNHIF_00824 4e-35
NIEPNHIF_00825 2.5e-33 gepA S Protein of unknown function (DUF4065)
NIEPNHIF_00826 2.4e-51 S Domain of unknown function DUF1829
NIEPNHIF_00827 5.9e-24
NIEPNHIF_00828 5.8e-188 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIEPNHIF_00829 0.0 L AAA domain
NIEPNHIF_00830 2.8e-232 yhaO L Ser Thr phosphatase family protein
NIEPNHIF_00831 7.2e-56 yheA S Belongs to the UPF0342 family
NIEPNHIF_00832 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NIEPNHIF_00833 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIEPNHIF_00834 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NIEPNHIF_00835 2.3e-110 G Phosphoglycerate mutase family
NIEPNHIF_00836 1e-139 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NIEPNHIF_00837 8.4e-179 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEPNHIF_00838 4.7e-56 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEPNHIF_00839 7.5e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIEPNHIF_00840 1.3e-54
NIEPNHIF_00841 3.2e-147 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NIEPNHIF_00842 6.9e-155 yisY 1.11.1.10 S Alpha/beta hydrolase family
NIEPNHIF_00843 3.8e-122 mdcG 2.7.7.66 H Phosphoribosyl-dephospho-CoA transferase MdcG
NIEPNHIF_00844 3.5e-302 mdcD 4.1.1.87 I Malonate decarboxylase gamma subunit (MdcE)
NIEPNHIF_00845 7.1e-52 mdcC C Malonate decarboxylase delta subunit (MdcD)
NIEPNHIF_00846 0.0 mdcA 2.3.1.187 I Malonate decarboxylase, alpha subunit, transporter
NIEPNHIF_00847 2.3e-170 mdcH 2.3.1.39 I Acyl transferase domain
NIEPNHIF_00848 2.9e-54
NIEPNHIF_00849 7.6e-158 lanM KLT Protein kinase domain
NIEPNHIF_00850 3.4e-175 ABC-SBP S ABC transporter
NIEPNHIF_00851 7.4e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NIEPNHIF_00852 1.8e-136 XK27_08845 S ABC transporter, ATP-binding protein
NIEPNHIF_00853 4.4e-45
NIEPNHIF_00854 1.3e-37
NIEPNHIF_00855 2e-52 S Bacteriocin helveticin-J
NIEPNHIF_00856 5.7e-42
NIEPNHIF_00857 2.7e-41 ps115 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_00858 2.3e-81 E Zn peptidase
NIEPNHIF_00859 1.2e-247 G Major Facilitator
NIEPNHIF_00860 4.1e-18
NIEPNHIF_00861 1.2e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
NIEPNHIF_00862 7.1e-176 K AI-2E family transporter
NIEPNHIF_00863 0.0 oppA E ABC transporter substrate-binding protein
NIEPNHIF_00864 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
NIEPNHIF_00865 4.7e-43 S Domain of unknown function (DUF4430)
NIEPNHIF_00866 2.7e-24 S Domain of unknown function (DUF4430)
NIEPNHIF_00867 4.7e-54 S ECF transporter, substrate-specific component
NIEPNHIF_00868 2e-79 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
NIEPNHIF_00869 6.7e-147 S Putative ABC-transporter type IV
NIEPNHIF_00870 4.8e-10 S LPXTG cell wall anchor motif
NIEPNHIF_00871 1.7e-28
NIEPNHIF_00873 1.2e-255 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
NIEPNHIF_00874 9.9e-192 glf 5.4.99.9 M UDP-galactopyranose mutase
NIEPNHIF_00875 5.7e-19 cysE_1 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
NIEPNHIF_00876 2.7e-63 S Psort location CytoplasmicMembrane, score 9.99
NIEPNHIF_00877 6.3e-91 glfT1 1.1.1.133 S Glycosyltransferase like family 2
NIEPNHIF_00878 1.9e-105 M Glycosyl transferases group 1
NIEPNHIF_00879 2.8e-114 M Glycosyltransferase, group 1 family protein
NIEPNHIF_00880 8.4e-109 glfT1 1.1.1.133 S Glycosyltransferase like family 2
NIEPNHIF_00881 3.6e-110 cps1D M Domain of unknown function (DUF4422)
NIEPNHIF_00882 1.5e-96 rfbP 2.7.8.6 M Bacterial sugar transferase
NIEPNHIF_00883 4.5e-143 ywqE 3.1.3.48 GM PHP domain protein
NIEPNHIF_00884 6.5e-113 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NIEPNHIF_00885 1.2e-139 epsB M biosynthesis protein
NIEPNHIF_00886 5.2e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NIEPNHIF_00887 4.9e-41 relB L RelB antitoxin
NIEPNHIF_00889 1.5e-220 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIEPNHIF_00890 3.4e-178 S Cysteine-rich secretory protein family
NIEPNHIF_00892 1.2e-105
NIEPNHIF_00893 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NIEPNHIF_00894 0.0 copA 3.6.3.54 P P-type ATPase
NIEPNHIF_00895 3.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NIEPNHIF_00896 4.5e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NIEPNHIF_00897 5.7e-74 atkY K Penicillinase repressor
NIEPNHIF_00898 2.3e-72 S Putative adhesin
NIEPNHIF_00899 3.3e-56 K Helix-turn-helix domain
NIEPNHIF_00900 1.6e-225 pbuG S permease
NIEPNHIF_00901 5.4e-127 S haloacid dehalogenase-like hydrolase
NIEPNHIF_00902 5.3e-226 S cog cog1373
NIEPNHIF_00903 2.3e-60 K Transcriptional regulator
NIEPNHIF_00904 2.8e-12 K Transcriptional regulator
NIEPNHIF_00905 3.6e-42 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
NIEPNHIF_00907 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
NIEPNHIF_00908 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
NIEPNHIF_00909 3e-232 pbuG S permease
NIEPNHIF_00910 3.3e-121 K helix_turn_helix, mercury resistance
NIEPNHIF_00911 1.2e-147 S ABC-2 family transporter protein
NIEPNHIF_00912 3.7e-79 V ATPases associated with a variety of cellular activities
NIEPNHIF_00913 3.9e-92 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_00914 2.2e-230 pbuG S permease
NIEPNHIF_00915 2.4e-139 cof S haloacid dehalogenase-like hydrolase
NIEPNHIF_00916 3.3e-69
NIEPNHIF_00917 3.6e-128 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NIEPNHIF_00918 2.5e-118 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NIEPNHIF_00919 5.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIEPNHIF_00920 1.3e-159 yeaE S Aldo/keto reductase family
NIEPNHIF_00921 5.7e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
NIEPNHIF_00922 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
NIEPNHIF_00923 3.4e-283 xylG 3.6.3.17 S ABC transporter
NIEPNHIF_00924 1.5e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
NIEPNHIF_00925 4.7e-202 tcsA S ABC transporter substrate-binding protein PnrA-like
NIEPNHIF_00926 2.8e-100 S ECF transporter, substrate-specific component
NIEPNHIF_00927 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NIEPNHIF_00928 0.0 macB_3 V ABC transporter, ATP-binding protein
NIEPNHIF_00929 3.6e-194 S DUF218 domain
NIEPNHIF_00930 9.1e-121 S CAAX protease self-immunity
NIEPNHIF_00931 9.7e-110 ropB K Transcriptional regulator
NIEPNHIF_00932 3.2e-154 EGP Major facilitator Superfamily
NIEPNHIF_00933 1.2e-53
NIEPNHIF_00934 2.1e-157 mutR K Helix-turn-helix XRE-family like proteins
NIEPNHIF_00935 2.1e-74 S Putative adhesin
NIEPNHIF_00936 1.6e-64 V ABC transporter transmembrane region
NIEPNHIF_00937 3e-268 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NIEPNHIF_00938 1.7e-18
NIEPNHIF_00939 3.4e-184 L Psort location Cytoplasmic, score
NIEPNHIF_00940 8e-68 C lyase activity
NIEPNHIF_00941 1.9e-14
NIEPNHIF_00942 2.1e-77 L Transposase and inactivated derivatives, IS30 family
NIEPNHIF_00943 1.3e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
NIEPNHIF_00944 2.6e-166 yjjC V ABC transporter
NIEPNHIF_00945 2.1e-291 M Exporter of polyketide antibiotics
NIEPNHIF_00946 3.6e-114 K Transcriptional regulator
NIEPNHIF_00947 1.4e-39 L Integrase core domain
NIEPNHIF_00948 3.8e-188 V ABC transporter transmembrane region
NIEPNHIF_00949 5.7e-206 napA P Sodium/hydrogen exchanger family
NIEPNHIF_00950 5.7e-62
NIEPNHIF_00951 0.0 cadA P P-type ATPase
NIEPNHIF_00952 5.1e-81 ykuL S (CBS) domain
NIEPNHIF_00953 1.7e-215 ywhK S Membrane
NIEPNHIF_00954 4.7e-48
NIEPNHIF_00955 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
NIEPNHIF_00956 2e-288 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIEPNHIF_00957 1.2e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
NIEPNHIF_00958 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIEPNHIF_00959 5.2e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NIEPNHIF_00960 1.1e-167 pbpX2 V Beta-lactamase
NIEPNHIF_00961 7.4e-132 S Protein of unknown function (DUF975)
NIEPNHIF_00962 2.7e-137 lysA2 M Glycosyl hydrolases family 25
NIEPNHIF_00963 7.9e-291 ytgP S Polysaccharide biosynthesis protein
NIEPNHIF_00964 9.6e-36
NIEPNHIF_00965 0.0 XK27_06780 V ABC transporter permease
NIEPNHIF_00966 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
NIEPNHIF_00967 3.9e-72 L IS1381, transposase OrfA
NIEPNHIF_00968 3.4e-11 S Uncharacterised protein family (UPF0236)
NIEPNHIF_00969 7.3e-118 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NIEPNHIF_00970 1.1e-98
NIEPNHIF_00971 2e-109 K LysR substrate binding domain
NIEPNHIF_00972 1e-20
NIEPNHIF_00973 1.3e-215 S Sterol carrier protein domain
NIEPNHIF_00974 2e-97 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NIEPNHIF_00975 1.2e-107 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
NIEPNHIF_00976 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NIEPNHIF_00977 1e-136 arcA 3.5.3.6 E Arginine
NIEPNHIF_00978 3.7e-77 arcA 3.5.3.6 E Arginine
NIEPNHIF_00979 9e-137 lysR5 K LysR substrate binding domain
NIEPNHIF_00980 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
NIEPNHIF_00981 5.4e-09 S Metal binding domain of Ada
NIEPNHIF_00983 1.5e-12 ybhL S Belongs to the BI1 family
NIEPNHIF_00984 8.9e-46 ybhL S Belongs to the BI1 family
NIEPNHIF_00985 1.5e-184 S Bacterial protein of unknown function (DUF871)
NIEPNHIF_00986 1.2e-202 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NIEPNHIF_00988 4.6e-89 oppA E ABC transporter substrate-binding protein
NIEPNHIF_00989 3.1e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIEPNHIF_00990 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NIEPNHIF_00991 4.5e-102 srtA 3.4.22.70 M sortase family
NIEPNHIF_00992 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NIEPNHIF_00993 9.3e-80 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
NIEPNHIF_00994 5.8e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIEPNHIF_00995 0.0 dnaK O Heat shock 70 kDa protein
NIEPNHIF_00996 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIEPNHIF_00997 4.5e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIEPNHIF_00998 9.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NIEPNHIF_00999 3.4e-158 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIEPNHIF_01000 3e-60 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NIEPNHIF_01001 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NIEPNHIF_01002 3.2e-47 rplGA J ribosomal protein
NIEPNHIF_01003 8.8e-47 ylxR K Protein of unknown function (DUF448)
NIEPNHIF_01004 4.9e-197 nusA K Participates in both transcription termination and antitermination
NIEPNHIF_01005 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NIEPNHIF_01006 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIEPNHIF_01007 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIEPNHIF_01008 7.5e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NIEPNHIF_01009 9.6e-136 cdsA 2.7.7.41 I Belongs to the CDS family
NIEPNHIF_01010 1.6e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIEPNHIF_01011 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIEPNHIF_01012 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NIEPNHIF_01013 8.3e-185 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIEPNHIF_01014 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NIEPNHIF_01015 6.3e-193 yabB 2.1.1.223 L Methyltransferase small domain
NIEPNHIF_01016 1.9e-112 plsC 2.3.1.51 I Acyltransferase
NIEPNHIF_01017 4.1e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NIEPNHIF_01018 3.1e-99 L An automated process has identified a potential problem with this gene model
NIEPNHIF_01019 1.9e-131 S SLAP domain
NIEPNHIF_01020 8.7e-43 oppA E ABC transporter substrate-binding protein
NIEPNHIF_01021 1.1e-272 oppA E ABC transporter substrate-binding protein
NIEPNHIF_01022 4.4e-85 dps P Belongs to the Dps family
NIEPNHIF_01023 3.1e-22 npr 1.11.1.1 C NADH oxidase
NIEPNHIF_01024 0.0 pepO 3.4.24.71 O Peptidase family M13
NIEPNHIF_01025 0.0 mdlB V ABC transporter
NIEPNHIF_01026 0.0 mdlA V ABC transporter
NIEPNHIF_01027 3.3e-30 yneF S Uncharacterised protein family (UPF0154)
NIEPNHIF_01028 3e-38 ynzC S UPF0291 protein
NIEPNHIF_01029 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIEPNHIF_01030 3.7e-145 E GDSL-like Lipase/Acylhydrolase family
NIEPNHIF_01031 1.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
NIEPNHIF_01032 1.4e-214 S SLAP domain
NIEPNHIF_01033 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NIEPNHIF_01034 5e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NIEPNHIF_01035 2.2e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIEPNHIF_01036 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NIEPNHIF_01037 5.8e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIEPNHIF_01038 1.2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NIEPNHIF_01039 3.2e-259 yfnA E amino acid
NIEPNHIF_01040 0.0 V FtsX-like permease family
NIEPNHIF_01041 2.4e-133 cysA V ABC transporter, ATP-binding protein
NIEPNHIF_01042 4.2e-08
NIEPNHIF_01043 5.5e-288 pipD E Dipeptidase
NIEPNHIF_01044 7.8e-164 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIEPNHIF_01045 0.0 smc D Required for chromosome condensation and partitioning
NIEPNHIF_01046 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIEPNHIF_01047 4.9e-310 oppA E ABC transporter substrate-binding protein
NIEPNHIF_01048 5.6e-239 oppA E ABC transporter substrate-binding protein
NIEPNHIF_01049 1.3e-63 oppA E ABC transporter substrate-binding protein
NIEPNHIF_01050 6.2e-131 oppC P Binding-protein-dependent transport system inner membrane component
NIEPNHIF_01051 9.8e-172 oppB P ABC transporter permease
NIEPNHIF_01052 8.8e-168 oppF P Belongs to the ABC transporter superfamily
NIEPNHIF_01053 1.1e-192 oppD P Belongs to the ABC transporter superfamily
NIEPNHIF_01054 1.8e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIEPNHIF_01055 2.7e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NIEPNHIF_01056 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIEPNHIF_01057 4.4e-305 yloV S DAK2 domain fusion protein YloV
NIEPNHIF_01058 4e-57 asp S Asp23 family, cell envelope-related function
NIEPNHIF_01059 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NIEPNHIF_01060 1.4e-30
NIEPNHIF_01061 1.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
NIEPNHIF_01062 6.5e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NIEPNHIF_01063 1.3e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NIEPNHIF_01064 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NIEPNHIF_01065 1.3e-139 stp 3.1.3.16 T phosphatase
NIEPNHIF_01066 6.1e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NIEPNHIF_01067 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIEPNHIF_01068 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIEPNHIF_01069 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIEPNHIF_01070 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NIEPNHIF_01071 1.1e-77 6.3.3.2 S ASCH
NIEPNHIF_01072 1.5e-308 recN L May be involved in recombinational repair of damaged DNA
NIEPNHIF_01073 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NIEPNHIF_01074 2.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NIEPNHIF_01075 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIEPNHIF_01076 7.6e-194 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIEPNHIF_01077 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NIEPNHIF_01078 2.1e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NIEPNHIF_01079 3.4e-71 yqhY S Asp23 family, cell envelope-related function
NIEPNHIF_01080 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIEPNHIF_01081 6.6e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NIEPNHIF_01082 7.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NIEPNHIF_01083 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NIEPNHIF_01084 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIEPNHIF_01085 2.7e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
NIEPNHIF_01087 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NIEPNHIF_01088 3.6e-300 S Predicted membrane protein (DUF2207)
NIEPNHIF_01089 1.6e-160 cinI S Serine hydrolase (FSH1)
NIEPNHIF_01090 1.9e-207 M Glycosyl hydrolases family 25
NIEPNHIF_01092 8.5e-178 I Carboxylesterase family
NIEPNHIF_01093 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
NIEPNHIF_01094 8e-280 V ABC-type multidrug transport system, ATPase and permease components
NIEPNHIF_01095 2e-291 V ABC-type multidrug transport system, ATPase and permease components
NIEPNHIF_01096 1.7e-148 S haloacid dehalogenase-like hydrolase
NIEPNHIF_01097 2.6e-52
NIEPNHIF_01098 1.9e-37
NIEPNHIF_01099 1.2e-42 S Alpha beta hydrolase
NIEPNHIF_01100 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NIEPNHIF_01101 5.2e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NIEPNHIF_01102 1.3e-44
NIEPNHIF_01103 6.1e-149 glcU U sugar transport
NIEPNHIF_01104 9.9e-251 lctP C L-lactate permease
NIEPNHIF_01105 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NIEPNHIF_01106 2.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NIEPNHIF_01107 1.3e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIEPNHIF_01108 1.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NIEPNHIF_01109 4.6e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIEPNHIF_01110 6.3e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIEPNHIF_01111 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NIEPNHIF_01112 1.1e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIEPNHIF_01113 3.4e-19 clcA P chloride
NIEPNHIF_01114 3.3e-37 clcA P chloride
NIEPNHIF_01115 4.2e-286 lsa S ABC transporter
NIEPNHIF_01116 3.7e-45
NIEPNHIF_01117 3.4e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NIEPNHIF_01118 5.5e-153 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NIEPNHIF_01119 1.3e-51 S Iron-sulfur cluster assembly protein
NIEPNHIF_01120 8.2e-117 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NIEPNHIF_01121 3.4e-48 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NIEPNHIF_01122 6.4e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NIEPNHIF_01123 8.4e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIEPNHIF_01124 4e-198 yjeM E Amino Acid
NIEPNHIF_01125 1.8e-60 yjeM E Amino Acid
NIEPNHIF_01126 8.4e-188 S SLAP domain
NIEPNHIF_01127 2.3e-100 S SLAP domain
NIEPNHIF_01128 6.1e-12 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NIEPNHIF_01129 1.2e-129 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEPNHIF_01130 2.7e-185 ulaA 2.7.1.194 S PTS system sugar-specific permease component
NIEPNHIF_01131 5.3e-23 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
NIEPNHIF_01132 4.3e-45 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEPNHIF_01133 1.8e-62 kdsD 5.3.1.13 M SIS domain
NIEPNHIF_01134 9.1e-87 dapA 4.3.3.7 H Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIEPNHIF_01135 5.2e-68 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
NIEPNHIF_01136 3.3e-70 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NIEPNHIF_01137 0.0 4.2.1.53 S Myosin-crossreactive antigen
NIEPNHIF_01138 2e-91 yxdD K Bacterial regulatory proteins, tetR family
NIEPNHIF_01139 1.7e-260 emrY EGP Major facilitator Superfamily
NIEPNHIF_01144 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
NIEPNHIF_01145 2.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIEPNHIF_01146 9.2e-200 pbpX V Beta-lactamase
NIEPNHIF_01147 2.8e-244 nhaC C Na H antiporter NhaC
NIEPNHIF_01148 1.8e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
NIEPNHIF_01149 2.6e-57
NIEPNHIF_01150 4.3e-108 ybhL S Belongs to the BI1 family
NIEPNHIF_01151 7.2e-172 yegS 2.7.1.107 G Lipid kinase
NIEPNHIF_01152 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIEPNHIF_01153 5.2e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIEPNHIF_01154 5.8e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIEPNHIF_01155 5.4e-201 camS S sex pheromone
NIEPNHIF_01156 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIEPNHIF_01157 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NIEPNHIF_01158 2.5e-86 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
NIEPNHIF_01160 2.8e-84 ydcK S Belongs to the SprT family
NIEPNHIF_01161 9.1e-135 M Glycosyltransferase sugar-binding region containing DXD motif
NIEPNHIF_01162 6.4e-260 epsU S Polysaccharide biosynthesis protein
NIEPNHIF_01163 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIEPNHIF_01164 0.0 pacL 3.6.3.8 P P-type ATPase
NIEPNHIF_01165 4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NIEPNHIF_01166 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIEPNHIF_01167 9e-206 csaB M Glycosyl transferases group 1
NIEPNHIF_01168 4.3e-135 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NIEPNHIF_01169 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NIEPNHIF_01170 4.6e-123 gntR1 K UTRA
NIEPNHIF_01171 1.1e-179
NIEPNHIF_01172 5.5e-300 oppA2 E ABC transporter, substratebinding protein
NIEPNHIF_01175 1.1e-240 npr 1.11.1.1 C NADH oxidase
NIEPNHIF_01176 7.7e-12
NIEPNHIF_01177 1.3e-22 3.6.4.12 S transposase or invertase
NIEPNHIF_01178 4.9e-87 S SLAP domain
NIEPNHIF_01179 2.9e-143 K SIS domain
NIEPNHIF_01180 2.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NIEPNHIF_01181 2.1e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
NIEPNHIF_01182 7.7e-219 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NIEPNHIF_01184 2.8e-112 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NIEPNHIF_01185 3.1e-116 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NIEPNHIF_01186 5.4e-87 G Histidine phosphatase superfamily (branch 1)
NIEPNHIF_01187 1.2e-105 G Phosphoglycerate mutase family
NIEPNHIF_01188 1.5e-160 D nuclear chromosome segregation
NIEPNHIF_01189 6.8e-79 M LysM domain protein
NIEPNHIF_01190 1.1e-28 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEPNHIF_01191 1.1e-115 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEPNHIF_01192 3.6e-254 L Putative transposase DNA-binding domain
NIEPNHIF_01193 4.1e-118 L Resolvase, N-terminal
NIEPNHIF_01194 6.2e-12
NIEPNHIF_01195 2.3e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
NIEPNHIF_01196 4.6e-31
NIEPNHIF_01197 1.1e-179 L COG2963 Transposase and inactivated derivatives
NIEPNHIF_01199 1.5e-70 S Iron-sulphur cluster biosynthesis
NIEPNHIF_01200 3.8e-113 yncA 2.3.1.79 S Maltose acetyltransferase
NIEPNHIF_01201 1e-61 psiE S Phosphate-starvation-inducible E
NIEPNHIF_01203 8.4e-142 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NIEPNHIF_01204 1.9e-59
NIEPNHIF_01205 0.0 lhr L DEAD DEAH box helicase
NIEPNHIF_01206 5.4e-253 P P-loop Domain of unknown function (DUF2791)
NIEPNHIF_01207 0.0 S TerB-C domain
NIEPNHIF_01208 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NIEPNHIF_01209 3.9e-298 V ABC transporter transmembrane region
NIEPNHIF_01211 6.7e-156 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_01212 7.2e-71 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NIEPNHIF_01213 4.7e-32
NIEPNHIF_01214 2.3e-169 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIEPNHIF_01215 1.6e-07 ackA 2.7.2.1 F acetate kinase activity
NIEPNHIF_01216 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIEPNHIF_01217 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NIEPNHIF_01218 1.6e-244 cycA E Amino acid permease
NIEPNHIF_01219 6.9e-87 maa S transferase hexapeptide repeat
NIEPNHIF_01220 8.7e-159 K Transcriptional regulator
NIEPNHIF_01221 9.9e-64 manO S Domain of unknown function (DUF956)
NIEPNHIF_01222 1e-173 manN G system, mannose fructose sorbose family IID component
NIEPNHIF_01223 1.7e-129 manY G PTS system
NIEPNHIF_01224 8.7e-187 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NIEPNHIF_01225 7.3e-69 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
NIEPNHIF_01226 5.6e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIEPNHIF_01227 3.9e-25
NIEPNHIF_01228 2.8e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
NIEPNHIF_01229 2e-135 ecsA V ABC transporter, ATP-binding protein
NIEPNHIF_01230 2.9e-221 ecsB U ABC transporter
NIEPNHIF_01231 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NIEPNHIF_01233 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NIEPNHIF_01234 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIEPNHIF_01235 2.7e-249 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NIEPNHIF_01236 6e-236 mepA V MATE efflux family protein
NIEPNHIF_01237 1.5e-175 S SLAP domain
NIEPNHIF_01238 1.1e-286 M Peptidase family M1 domain
NIEPNHIF_01239 1.2e-193 S Bacteriocin helveticin-J
NIEPNHIF_01240 4.7e-21
NIEPNHIF_01241 5.7e-52 L RelB antitoxin
NIEPNHIF_01242 2e-139 qmcA O prohibitin homologues
NIEPNHIF_01243 8e-16 darA C Flavodoxin
NIEPNHIF_01244 1.6e-65 darA C Flavodoxin
NIEPNHIF_01245 1.2e-171 purD 6.3.4.13 F Belongs to the GARS family
NIEPNHIF_01246 0.0 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
NIEPNHIF_01247 5.7e-288 hsdM 2.1.1.72 V type I restriction-modification system
NIEPNHIF_01248 5.3e-100 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NIEPNHIF_01251 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NIEPNHIF_01252 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NIEPNHIF_01253 1.2e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIEPNHIF_01254 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIEPNHIF_01255 2.3e-251 dnaB L Replication initiation and membrane attachment
NIEPNHIF_01256 1.3e-168 dnaI L Primosomal protein DnaI
NIEPNHIF_01257 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIEPNHIF_01258 1.7e-85
NIEPNHIF_01259 2e-178 UW LPXTG-motif cell wall anchor domain protein
NIEPNHIF_01260 9.6e-45 UW LPXTG-motif cell wall anchor domain protein
NIEPNHIF_01261 1.3e-31 UW LPXTG-motif cell wall anchor domain protein
NIEPNHIF_01262 2.8e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NIEPNHIF_01263 3.4e-100 J Acetyltransferase (GNAT) domain
NIEPNHIF_01264 1.8e-110 yjbF S SNARE associated Golgi protein
NIEPNHIF_01265 6.5e-153 I alpha/beta hydrolase fold
NIEPNHIF_01266 3.8e-159 hipB K Helix-turn-helix
NIEPNHIF_01267 2.4e-92 F Nucleoside 2-deoxyribosyltransferase
NIEPNHIF_01268 1.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NIEPNHIF_01269 2.6e-162
NIEPNHIF_01270 1.3e-25 K Acetyltransferase (GNAT) domain
NIEPNHIF_01272 0.0 ydgH S MMPL family
NIEPNHIF_01273 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
NIEPNHIF_01274 2e-148 3.5.2.6 V Beta-lactamase enzyme family
NIEPNHIF_01275 1.8e-154 corA P CorA-like Mg2+ transporter protein
NIEPNHIF_01276 2.5e-239 G Bacterial extracellular solute-binding protein
NIEPNHIF_01277 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
NIEPNHIF_01278 1.4e-145 gtsC P Binding-protein-dependent transport system inner membrane component
NIEPNHIF_01279 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
NIEPNHIF_01280 9.3e-203 malK P ATPases associated with a variety of cellular activities
NIEPNHIF_01281 1.8e-283 pipD E Dipeptidase
NIEPNHIF_01282 4.2e-158 endA F DNA RNA non-specific endonuclease
NIEPNHIF_01283 1.4e-181 dnaQ 2.7.7.7 L EXOIII
NIEPNHIF_01284 2.4e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NIEPNHIF_01285 3e-116 yviA S Protein of unknown function (DUF421)
NIEPNHIF_01286 1.1e-72 S Protein of unknown function (DUF3290)
NIEPNHIF_01287 9e-141 pnuC H nicotinamide mononucleotide transporter
NIEPNHIF_01288 1.4e-13
NIEPNHIF_01289 4.6e-129 S PAS domain
NIEPNHIF_01290 4.2e-276 V ABC transporter transmembrane region
NIEPNHIF_01291 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NIEPNHIF_01292 6.3e-131 T Transcriptional regulatory protein, C terminal
NIEPNHIF_01293 2.2e-246 T GHKL domain
NIEPNHIF_01294 1.6e-86 S Peptidase propeptide and YPEB domain
NIEPNHIF_01295 1.5e-101 S Peptidase propeptide and YPEB domain
NIEPNHIF_01296 1.3e-96 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NIEPNHIF_01297 6.2e-76 yybA 2.3.1.57 K Transcriptional regulator
NIEPNHIF_01298 8.9e-242 V ABC transporter transmembrane region
NIEPNHIF_01299 3.4e-310 oppA3 E ABC transporter, substratebinding protein
NIEPNHIF_01300 9.9e-62 ypaA S Protein of unknown function (DUF1304)
NIEPNHIF_01301 1.5e-101 S Peptidase propeptide and YPEB domain
NIEPNHIF_01302 4.4e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIEPNHIF_01303 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
NIEPNHIF_01304 1.1e-98 E GDSL-like Lipase/Acylhydrolase
NIEPNHIF_01305 3.7e-73 yjcF S Acetyltransferase (GNAT) domain
NIEPNHIF_01306 1.1e-139 aatB ET ABC transporter substrate-binding protein
NIEPNHIF_01307 7.1e-107 glnQ 3.6.3.21 E ABC transporter
NIEPNHIF_01308 4.2e-110 glnP P ABC transporter permease
NIEPNHIF_01309 0.0 helD 3.6.4.12 L DNA helicase
NIEPNHIF_01310 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NIEPNHIF_01311 3.2e-126 pgm3 G Phosphoglycerate mutase family
NIEPNHIF_01312 9.1e-242 S response to antibiotic
NIEPNHIF_01313 2.9e-125
NIEPNHIF_01314 0.0 3.6.3.8 P P-type ATPase
NIEPNHIF_01315 8.7e-66 2.7.1.191 G PTS system fructose IIA component
NIEPNHIF_01316 7.7e-09
NIEPNHIF_01317 1.5e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
NIEPNHIF_01318 1.8e-136 glvR K Helix-turn-helix domain, rpiR family
NIEPNHIF_01319 2.3e-267 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
NIEPNHIF_01320 1.1e-150
NIEPNHIF_01321 8.6e-24
NIEPNHIF_01322 7.8e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NIEPNHIF_01323 2e-157 S Archaea bacterial proteins of unknown function
NIEPNHIF_01324 2.5e-106 3.2.2.20 K acetyltransferase
NIEPNHIF_01326 9.5e-81 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NIEPNHIF_01327 7.6e-39 KQ helix_turn_helix, mercury resistance
NIEPNHIF_01329 1.2e-142 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIEPNHIF_01330 1.9e-56 L Transposase
NIEPNHIF_01331 1e-248 S Uncharacterised protein family (UPF0236)
NIEPNHIF_01332 8.8e-16 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NIEPNHIF_01333 9e-30 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NIEPNHIF_01334 1.8e-86 dcm 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NIEPNHIF_01335 2.1e-85 S AAA ATPase domain
NIEPNHIF_01336 3.5e-09 S Domain of unknown function (DUF3841)
NIEPNHIF_01337 4.2e-151 S Domain of unknown function (DUF3883)
NIEPNHIF_01338 1.4e-114 mrr L restriction endonuclease
NIEPNHIF_01339 3.7e-63 3.1.21.3 V Type I restriction modification DNA specificity domain
NIEPNHIF_01340 1.4e-151 L Belongs to the 'phage' integrase family
NIEPNHIF_01341 1.1e-55 3.1.21.3 V Type I restriction modification DNA specificity domain
NIEPNHIF_01342 2.3e-221 hsdM 2.1.1.72 V type I restriction-modification system
NIEPNHIF_01343 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NIEPNHIF_01344 7.6e-29 S CAAX amino terminal protease
NIEPNHIF_01346 6.3e-46
NIEPNHIF_01347 4.9e-159 S reductase
NIEPNHIF_01348 2.1e-34
NIEPNHIF_01349 8e-293 K Putative DNA-binding domain
NIEPNHIF_01350 5.8e-239 pyrP F Permease
NIEPNHIF_01351 4.7e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIEPNHIF_01352 1.6e-261 emrY EGP Major facilitator Superfamily
NIEPNHIF_01353 5.6e-217 mdtG EGP Major facilitator Superfamily
NIEPNHIF_01354 2.4e-136
NIEPNHIF_01355 2.6e-103
NIEPNHIF_01356 6e-210 pepA E M42 glutamyl aminopeptidase
NIEPNHIF_01357 2e-310 ybiT S ABC transporter, ATP-binding protein
NIEPNHIF_01358 1.3e-173 S Aldo keto reductase
NIEPNHIF_01359 5.5e-138
NIEPNHIF_01360 3.4e-239 steT E amino acid
NIEPNHIF_01361 3.3e-242 steT E amino acid
NIEPNHIF_01362 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
NIEPNHIF_01363 2.4e-147 glnH ET ABC transporter
NIEPNHIF_01364 1.4e-80 K Transcriptional regulator, MarR family
NIEPNHIF_01365 6.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
NIEPNHIF_01366 0.0 V ABC transporter transmembrane region
NIEPNHIF_01367 3.8e-102 S ABC-type cobalt transport system, permease component
NIEPNHIF_01368 3.1e-251 G MFS/sugar transport protein
NIEPNHIF_01369 3.6e-114 udk 2.7.1.48 F Zeta toxin
NIEPNHIF_01370 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIEPNHIF_01371 2.4e-150 glnH ET ABC transporter substrate-binding protein
NIEPNHIF_01372 9.7e-91 gluC P ABC transporter permease
NIEPNHIF_01373 4.7e-109 glnP P ABC transporter permease
NIEPNHIF_01374 1.2e-163 S Protein of unknown function (DUF2974)
NIEPNHIF_01375 3.3e-86
NIEPNHIF_01376 4.9e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
NIEPNHIF_01377 2.9e-235 G Bacterial extracellular solute-binding protein
NIEPNHIF_01378 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
NIEPNHIF_01379 1.6e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIEPNHIF_01380 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NIEPNHIF_01381 0.0 kup P Transport of potassium into the cell
NIEPNHIF_01382 2.8e-176 rihB 3.2.2.1 F Nucleoside
NIEPNHIF_01383 1.4e-133 ydhQ K UbiC transcription regulator-associated domain protein
NIEPNHIF_01384 1.2e-154 S hydrolase
NIEPNHIF_01385 1e-60 S Enterocin A Immunity
NIEPNHIF_01386 3.3e-138 glcR K DeoR C terminal sensor domain
NIEPNHIF_01387 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NIEPNHIF_01388 5.8e-160 rssA S Phospholipase, patatin family
NIEPNHIF_01389 5.7e-149 S hydrolase
NIEPNHIF_01390 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
NIEPNHIF_01391 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
NIEPNHIF_01392 7e-81
NIEPNHIF_01393 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NIEPNHIF_01394 2.1e-39
NIEPNHIF_01395 2.3e-119 C nitroreductase
NIEPNHIF_01396 1.8e-248 yhdP S Transporter associated domain
NIEPNHIF_01397 3.7e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NIEPNHIF_01398 0.0 1.3.5.4 C FAD binding domain
NIEPNHIF_01399 4.1e-90 L PFAM transposase, IS4 family protein
NIEPNHIF_01400 0.0 1.3.5.4 C FAD binding domain
NIEPNHIF_01401 9.7e-231 potE E amino acid
NIEPNHIF_01402 4.7e-131 M Glycosyl hydrolases family 25
NIEPNHIF_01403 1.2e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
NIEPNHIF_01404 6.2e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEPNHIF_01406 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NIEPNHIF_01407 3.1e-87 gtcA S Teichoic acid glycosylation protein
NIEPNHIF_01408 4.1e-80 fld C Flavodoxin
NIEPNHIF_01409 6.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
NIEPNHIF_01410 4.7e-163 yihY S Belongs to the UPF0761 family
NIEPNHIF_01411 7.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NIEPNHIF_01412 1.5e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
NIEPNHIF_01413 6.3e-216 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NIEPNHIF_01414 1.9e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NIEPNHIF_01415 9.4e-46
NIEPNHIF_01416 7.5e-177 D Alpha beta
NIEPNHIF_01417 3.5e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIEPNHIF_01418 1.9e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
NIEPNHIF_01419 3.5e-85
NIEPNHIF_01420 1.6e-74
NIEPNHIF_01421 1.1e-140 hlyX S Transporter associated domain
NIEPNHIF_01422 3.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NIEPNHIF_01423 2.4e-147
NIEPNHIF_01424 3.2e-265 V ABC transporter transmembrane region
NIEPNHIF_01425 1.8e-16
NIEPNHIF_01426 6.6e-51 L Transposase
NIEPNHIF_01427 5.2e-30
NIEPNHIF_01428 9.6e-43 XK27_09445 S Domain of unknown function (DUF1827)
NIEPNHIF_01429 0.0 clpE O Belongs to the ClpA ClpB family
NIEPNHIF_01430 5.3e-26
NIEPNHIF_01431 8.5e-41 ptsH G phosphocarrier protein HPR
NIEPNHIF_01432 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIEPNHIF_01433 6.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NIEPNHIF_01434 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NIEPNHIF_01435 5.8e-160 coiA 3.6.4.12 S Competence protein
NIEPNHIF_01436 1.2e-114 yjbH Q Thioredoxin
NIEPNHIF_01437 8e-111 yjbK S CYTH
NIEPNHIF_01438 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
NIEPNHIF_01439 1.9e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIEPNHIF_01440 7.1e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIEPNHIF_01441 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NIEPNHIF_01442 3.2e-92 S SNARE associated Golgi protein
NIEPNHIF_01443 1.8e-45
NIEPNHIF_01444 1.5e-124 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
NIEPNHIF_01445 9.3e-81 S AAA domain
NIEPNHIF_01446 6.9e-144 2.4.2.3 F Phosphorylase superfamily
NIEPNHIF_01447 2.1e-145 2.4.2.3 F Phosphorylase superfamily
NIEPNHIF_01448 2.8e-73 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
NIEPNHIF_01449 3.1e-26 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
NIEPNHIF_01450 3.5e-26 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
NIEPNHIF_01451 1.9e-149 yagE E Amino acid permease
NIEPNHIF_01452 1.9e-86 3.4.21.96 S SLAP domain
NIEPNHIF_01453 3.9e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIEPNHIF_01454 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NIEPNHIF_01455 1.2e-107 hlyIII S protein, hemolysin III
NIEPNHIF_01456 9.8e-144 DegV S Uncharacterised protein, DegV family COG1307
NIEPNHIF_01457 7.1e-36 yozE S Belongs to the UPF0346 family
NIEPNHIF_01458 3.6e-40 yjcE P NhaP-type Na H and K H
NIEPNHIF_01459 5.9e-181 yjcE P Sodium proton antiporter
NIEPNHIF_01460 7.3e-155 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NIEPNHIF_01461 2.3e-131 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIEPNHIF_01462 1e-151 dprA LU DNA protecting protein DprA
NIEPNHIF_01463 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIEPNHIF_01464 2.7e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NIEPNHIF_01465 2.2e-141 xerC D Phage integrase, N-terminal SAM-like domain
NIEPNHIF_01466 3.3e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NIEPNHIF_01467 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NIEPNHIF_01468 1.8e-180 lacX 5.1.3.3 G Aldose 1-epimerase
NIEPNHIF_01469 9.8e-61 C Aldo keto reductase
NIEPNHIF_01470 3.7e-44 S aldo-keto reductase (NADP) activity
NIEPNHIF_01471 3e-61 M LysM domain protein
NIEPNHIF_01472 1.1e-152 xerD L Phage integrase, N-terminal SAM-like domain
NIEPNHIF_01473 7.9e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIEPNHIF_01474 2.7e-64 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIEPNHIF_01475 2.9e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NIEPNHIF_01476 1.2e-116 mmuP E amino acid
NIEPNHIF_01477 1.3e-273 pepV 3.5.1.18 E dipeptidase PepV
NIEPNHIF_01478 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
NIEPNHIF_01479 1.7e-284 E Amino acid permease
NIEPNHIF_01480 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NIEPNHIF_01481 6.7e-245 ynbB 4.4.1.1 P aluminum resistance
NIEPNHIF_01482 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NIEPNHIF_01483 3.4e-82 C Flavodoxin
NIEPNHIF_01484 0.0 uvrA3 L excinuclease ABC, A subunit
NIEPNHIF_01485 4.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NIEPNHIF_01486 1e-113 3.6.1.27 I Acid phosphatase homologues
NIEPNHIF_01487 1.3e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEPNHIF_01488 3.7e-165 S Alpha/beta hydrolase of unknown function (DUF915)
NIEPNHIF_01489 0.0 clpE O AAA domain (Cdc48 subfamily)
NIEPNHIF_01490 2.7e-123 yoaK S Protein of unknown function (DUF1275)
NIEPNHIF_01491 2e-39 S Transglycosylase associated protein
NIEPNHIF_01492 1.5e-211 M Glycosyl hydrolases family 25
NIEPNHIF_01493 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
NIEPNHIF_01494 4.1e-67
NIEPNHIF_01495 1.8e-203 xerS L Belongs to the 'phage' integrase family
NIEPNHIF_01496 1.3e-305 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NIEPNHIF_01497 3.5e-160 degV S EDD domain protein, DegV family
NIEPNHIF_01498 1.1e-66
NIEPNHIF_01499 0.0 FbpA K Fibronectin-binding protein
NIEPNHIF_01500 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
NIEPNHIF_01501 4.6e-199 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NIEPNHIF_01502 6.2e-168 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIEPNHIF_01503 2.8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIEPNHIF_01504 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NIEPNHIF_01505 5.5e-53
NIEPNHIF_01506 4.4e-158 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
NIEPNHIF_01507 2.6e-13 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NIEPNHIF_01509 3.5e-35
NIEPNHIF_01511 4.8e-42 lemA S LemA family
NIEPNHIF_01513 2.1e-18 S TPM domain
NIEPNHIF_01516 4.9e-52
NIEPNHIF_01517 1.9e-15 D nuclear chromosome segregation
NIEPNHIF_01518 6.7e-12
NIEPNHIF_01519 1.9e-68 S Bacterial mobilisation protein (MobC)
NIEPNHIF_01520 4.6e-23
NIEPNHIF_01521 7.2e-32 S Helix-turn-helix domain
NIEPNHIF_01522 0.0 tetP J Elongation factor G, domain IV
NIEPNHIF_01523 9.3e-63 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
NIEPNHIF_01524 9.7e-74 S Sel1-like repeats.
NIEPNHIF_01525 2e-103 3.1.4.37 S AAA domain
NIEPNHIF_01526 2.1e-180
NIEPNHIF_01527 4.7e-31
NIEPNHIF_01528 3.2e-77 S HIRAN
NIEPNHIF_01529 9.3e-69 S Sel1-like repeats.
NIEPNHIF_01530 7.1e-79
NIEPNHIF_01531 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NIEPNHIF_01532 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NIEPNHIF_01533 4.9e-213 yubA S AI-2E family transporter
NIEPNHIF_01534 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NIEPNHIF_01535 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
NIEPNHIF_01536 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NIEPNHIF_01537 2.6e-222 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
NIEPNHIF_01538 3.9e-237 S Peptidase M16
NIEPNHIF_01539 1.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
NIEPNHIF_01540 5.2e-97 ymfM S Helix-turn-helix domain
NIEPNHIF_01541 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIEPNHIF_01542 8.5e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIEPNHIF_01543 5.7e-220 rny S Endoribonuclease that initiates mRNA decay
NIEPNHIF_01544 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
NIEPNHIF_01545 1.9e-118 yvyE 3.4.13.9 S YigZ family
NIEPNHIF_01546 3e-245 comFA L Helicase C-terminal domain protein
NIEPNHIF_01547 2.5e-132 comFC S Competence protein
NIEPNHIF_01548 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIEPNHIF_01549 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIEPNHIF_01550 4.9e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIEPNHIF_01551 5.1e-17
NIEPNHIF_01552 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NIEPNHIF_01553 4.6e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIEPNHIF_01554 3.3e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NIEPNHIF_01555 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIEPNHIF_01556 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NIEPNHIF_01557 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NIEPNHIF_01558 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIEPNHIF_01559 1.1e-90 S Short repeat of unknown function (DUF308)
NIEPNHIF_01560 6.2e-165 rapZ S Displays ATPase and GTPase activities
NIEPNHIF_01561 1.2e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NIEPNHIF_01562 2.1e-171 whiA K May be required for sporulation
NIEPNHIF_01563 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIEPNHIF_01564 0.0 S SH3-like domain
NIEPNHIF_01565 4.9e-111 ybbL S ABC transporter, ATP-binding protein
NIEPNHIF_01566 4.3e-130 ybbM S Uncharacterised protein family (UPF0014)
NIEPNHIF_01567 4.3e-95 S Domain of unknown function (DUF4811)
NIEPNHIF_01568 6.4e-263 lmrB EGP Major facilitator Superfamily
NIEPNHIF_01569 1.4e-77 K MerR HTH family regulatory protein
NIEPNHIF_01570 2.8e-117 cylA V ABC transporter
NIEPNHIF_01571 3.4e-91 cylB V ABC-2 type transporter
NIEPNHIF_01572 6.7e-46 K LytTr DNA-binding domain
NIEPNHIF_01573 2.6e-33 S Protein of unknown function (DUF3021)
NIEPNHIF_01574 4e-139 S Cysteine-rich secretory protein family
NIEPNHIF_01575 5e-273 ycaM E amino acid
NIEPNHIF_01576 2.4e-289
NIEPNHIF_01578 1.5e-189 cggR K Putative sugar-binding domain
NIEPNHIF_01579 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIEPNHIF_01580 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NIEPNHIF_01581 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIEPNHIF_01582 1.2e-94
NIEPNHIF_01583 1.8e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
NIEPNHIF_01584 3.7e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIEPNHIF_01585 6.3e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NIEPNHIF_01586 1.4e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NIEPNHIF_01587 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
NIEPNHIF_01588 1.2e-163 murB 1.3.1.98 M Cell wall formation
NIEPNHIF_01589 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NIEPNHIF_01590 5.4e-131 potB P ABC transporter permease
NIEPNHIF_01591 2.1e-127 potC P ABC transporter permease
NIEPNHIF_01592 4.7e-207 potD P ABC transporter
NIEPNHIF_01593 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NIEPNHIF_01594 2e-172 ybbR S YbbR-like protein
NIEPNHIF_01595 9e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIEPNHIF_01596 1.4e-147 S hydrolase
NIEPNHIF_01597 1.8e-75 K Penicillinase repressor
NIEPNHIF_01598 2.5e-119
NIEPNHIF_01599 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIEPNHIF_01600 1.8e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NIEPNHIF_01601 1.7e-143 licT K CAT RNA binding domain
NIEPNHIF_01602 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
NIEPNHIF_01603 1.9e-299 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIEPNHIF_01604 3.4e-177 D Alpha beta
NIEPNHIF_01605 1.7e-304 E Amino acid permease
NIEPNHIF_01607 9.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIEPNHIF_01608 3.2e-110 ylbE GM NAD(P)H-binding
NIEPNHIF_01609 2e-94 S VanZ like family
NIEPNHIF_01610 8.9e-133 yebC K Transcriptional regulatory protein
NIEPNHIF_01611 1.9e-178 comGA NU Type II IV secretion system protein
NIEPNHIF_01612 2.7e-172 comGB NU type II secretion system
NIEPNHIF_01613 3.1e-43 comGC U competence protein ComGC
NIEPNHIF_01614 7.4e-71
NIEPNHIF_01615 2.3e-41
NIEPNHIF_01616 1.5e-76 comGF U Putative Competence protein ComGF
NIEPNHIF_01617 1.6e-21
NIEPNHIF_01618 3.5e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
NIEPNHIF_01619 5.4e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIEPNHIF_01621 4e-111 M Protein of unknown function (DUF3737)
NIEPNHIF_01622 2.7e-224 patB 4.4.1.8 E Aminotransferase, class I
NIEPNHIF_01623 1e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NIEPNHIF_01624 1.3e-66 S SdpI/YhfL protein family
NIEPNHIF_01625 2e-129 K Transcriptional regulatory protein, C terminal
NIEPNHIF_01626 3.6e-266 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
NIEPNHIF_01627 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIEPNHIF_01628 3.8e-105 vanZ V VanZ like family
NIEPNHIF_01629 2.2e-254 pgi 5.3.1.9 G Belongs to the GPI family
NIEPNHIF_01630 6.9e-219 EGP Major facilitator Superfamily
NIEPNHIF_01631 1e-195 ampC V Beta-lactamase
NIEPNHIF_01634 1.3e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NIEPNHIF_01635 4.9e-113 tdk 2.7.1.21 F thymidine kinase
NIEPNHIF_01636 6.9e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIEPNHIF_01637 2.5e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIEPNHIF_01638 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NIEPNHIF_01639 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIEPNHIF_01640 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
NIEPNHIF_01641 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIEPNHIF_01642 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIEPNHIF_01643 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIEPNHIF_01644 5.7e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIEPNHIF_01645 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIEPNHIF_01646 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIEPNHIF_01647 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NIEPNHIF_01648 4.1e-31 ywzB S Protein of unknown function (DUF1146)
NIEPNHIF_01649 2.5e-178 mbl D Cell shape determining protein MreB Mrl
NIEPNHIF_01650 5.9e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NIEPNHIF_01651 1.5e-33 S Protein of unknown function (DUF2969)
NIEPNHIF_01652 1.2e-216 rodA D Belongs to the SEDS family
NIEPNHIF_01653 1.2e-58
NIEPNHIF_01654 2.3e-138 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
NIEPNHIF_01656 7.7e-97 acfD M Membrane
NIEPNHIF_01657 5.9e-137 S response to antibiotic
NIEPNHIF_01658 8.9e-192
NIEPNHIF_01659 4.6e-126 S zinc-ribbon domain
NIEPNHIF_01660 3.7e-76 usp6 T universal stress protein
NIEPNHIF_01661 3.5e-37
NIEPNHIF_01662 7.4e-239 rarA L recombination factor protein RarA
NIEPNHIF_01663 9.9e-85 yueI S Protein of unknown function (DUF1694)
NIEPNHIF_01664 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIEPNHIF_01665 6.2e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NIEPNHIF_01666 4.3e-214 iscS2 2.8.1.7 E Aminotransferase class V
NIEPNHIF_01667 5.1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NIEPNHIF_01669 6.5e-81 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_01670 4.4e-62
NIEPNHIF_01671 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NIEPNHIF_01672 3e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NIEPNHIF_01673 4.5e-94 3.6.1.55 L NUDIX domain
NIEPNHIF_01674 2.6e-37
NIEPNHIF_01675 7.6e-46
NIEPNHIF_01676 6.4e-235 L Transposase
NIEPNHIF_01677 9.9e-208 S PFAM Archaeal ATPase
NIEPNHIF_01678 5.6e-85 S GyrI-like small molecule binding domain
NIEPNHIF_01679 1.9e-168 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIEPNHIF_01680 2.4e-206 S PFAM Archaeal ATPase
NIEPNHIF_01681 1.3e-215 I transferase activity, transferring acyl groups other than amino-acyl groups
NIEPNHIF_01682 2.5e-158 K Transcriptional regulator, LysR family
NIEPNHIF_01683 1.6e-40 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIEPNHIF_01684 3.8e-52 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIEPNHIF_01685 2.9e-38 S Aldo keto reductase
NIEPNHIF_01686 1.2e-38 hxlR K HxlR-like helix-turn-helix
NIEPNHIF_01687 1.6e-73 K LytTr DNA-binding domain
NIEPNHIF_01688 3.8e-75 S Protein of unknown function (DUF3021)
NIEPNHIF_01689 8.3e-168 V ABC transporter
NIEPNHIF_01690 3e-123 S domain protein
NIEPNHIF_01691 7.1e-106 yyaR K Acetyltransferase (GNAT) domain
NIEPNHIF_01692 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIEPNHIF_01693 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NIEPNHIF_01694 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIEPNHIF_01695 5.6e-154 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NIEPNHIF_01696 9.2e-201 tnpB L Putative transposase DNA-binding domain
NIEPNHIF_01697 4.2e-84 yqeG S HAD phosphatase, family IIIA
NIEPNHIF_01698 1.5e-200 yqeH S Ribosome biogenesis GTPase YqeH
NIEPNHIF_01699 8.3e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIEPNHIF_01700 6.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NIEPNHIF_01701 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIEPNHIF_01702 1.2e-216 ylbM S Belongs to the UPF0348 family
NIEPNHIF_01703 5.5e-98 yceD S Uncharacterized ACR, COG1399
NIEPNHIF_01704 1.2e-126 K response regulator
NIEPNHIF_01705 3.3e-278 arlS 2.7.13.3 T Histidine kinase
NIEPNHIF_01706 2.4e-50 S CAAX protease self-immunity
NIEPNHIF_01707 3.6e-224 S SLAP domain
NIEPNHIF_01708 1.6e-85 S Aminoacyl-tRNA editing domain
NIEPNHIF_01709 7.6e-164 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIEPNHIF_01710 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NIEPNHIF_01711 3.3e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIEPNHIF_01712 4.5e-58 yodB K Transcriptional regulator, HxlR family
NIEPNHIF_01714 4.4e-110 papP P ABC transporter, permease protein
NIEPNHIF_01715 2.8e-117 P ABC transporter permease
NIEPNHIF_01716 5.6e-65 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIEPNHIF_01717 1.2e-70 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NIEPNHIF_01718 1.8e-226 N Uncharacterized conserved protein (DUF2075)
NIEPNHIF_01719 6.2e-205 pbpX1 V Beta-lactamase
NIEPNHIF_01720 0.0 L Helicase C-terminal domain protein
NIEPNHIF_01721 7.3e-272 E amino acid
NIEPNHIF_01722 3.4e-157 xth 3.1.11.2 L exodeoxyribonuclease III
NIEPNHIF_01725 6.2e-193 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIEPNHIF_01726 4.8e-151 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
NIEPNHIF_01727 0.0 tetP J elongation factor G
NIEPNHIF_01728 1e-156 yvgN C Aldo keto reductase
NIEPNHIF_01729 5.1e-151 P CorA-like Mg2+ transporter protein
NIEPNHIF_01730 3.5e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NIEPNHIF_01731 6.4e-148 ropB K Helix-turn-helix domain
NIEPNHIF_01732 1.8e-287 V ABC-type multidrug transport system, ATPase and permease components
NIEPNHIF_01733 3.6e-106 tra L Transposase and inactivated derivatives, IS30 family
NIEPNHIF_01734 7.3e-145 E Amino acid permease
NIEPNHIF_01735 5e-218 L Transposase
NIEPNHIF_01736 1e-76 vatD S acetyltransferase'
NIEPNHIF_01737 1e-30
NIEPNHIF_01738 1.3e-53
NIEPNHIF_01739 3.9e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIEPNHIF_01740 1.1e-115
NIEPNHIF_01741 4.2e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NIEPNHIF_01742 2.5e-220 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NIEPNHIF_01743 1.6e-282 thrC 4.2.3.1 E Threonine synthase
NIEPNHIF_01744 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NIEPNHIF_01745 1.8e-101 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
NIEPNHIF_01746 0.0 L PLD-like domain
NIEPNHIF_01747 1.1e-78 hipB K sequence-specific DNA binding
NIEPNHIF_01748 6.6e-282 V ABC-type multidrug transport system, ATPase and permease components
NIEPNHIF_01749 2e-286 V ABC-type multidrug transport system, ATPase and permease components
NIEPNHIF_01750 2.1e-95
NIEPNHIF_01751 4.5e-94 rimL J Acetyltransferase (GNAT) domain
NIEPNHIF_01752 2.8e-140 S Alpha/beta hydrolase family
NIEPNHIF_01753 3.7e-73 yxaM EGP Major facilitator Superfamily
NIEPNHIF_01754 2e-39 L Transposase
NIEPNHIF_01755 1.3e-19
NIEPNHIF_01756 1.9e-20
NIEPNHIF_01757 1.1e-14 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_01758 4.8e-27 E Zn peptidase
NIEPNHIF_01759 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
NIEPNHIF_01760 3.4e-96 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_01761 3.4e-24 V ABC transporter transmembrane region
NIEPNHIF_01762 6.8e-66 L COG2826 Transposase and inactivated derivatives, IS30 family
NIEPNHIF_01763 1.3e-110 L COG2826 Transposase and inactivated derivatives, IS30 family
NIEPNHIF_01764 2.2e-146 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NIEPNHIF_01767 1e-24 L Transposase
NIEPNHIF_01768 1.2e-62 L Transposase
NIEPNHIF_01769 3.5e-172 L Bifunctional protein
NIEPNHIF_01770 7.9e-54 L Transposase
NIEPNHIF_01771 3.6e-31 L Transposase
NIEPNHIF_01772 2.8e-47 lysM M LysM domain
NIEPNHIF_01773 0.0 pepN 3.4.11.2 E aminopeptidase
NIEPNHIF_01774 1.6e-250 dtpT U amino acid peptide transporter
NIEPNHIF_01775 7.3e-19 S Sugar efflux transporter for intercellular exchange
NIEPNHIF_01776 9.3e-43 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIEPNHIF_01777 2.4e-161 cjaA ET ABC transporter substrate-binding protein
NIEPNHIF_01778 2.7e-199 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIEPNHIF_01779 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIEPNHIF_01780 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIEPNHIF_01781 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
NIEPNHIF_01782 3.2e-158 metQ1 P Belongs to the nlpA lipoprotein family
NIEPNHIF_01783 5.7e-25
NIEPNHIF_01784 0.0 mco Q Multicopper oxidase
NIEPNHIF_01785 2.4e-147 S Sucrose-6F-phosphate phosphohydrolase
NIEPNHIF_01786 0.0 oppA E ABC transporter
NIEPNHIF_01787 7.3e-233 Q Imidazolonepropionase and related amidohydrolases
NIEPNHIF_01788 7.3e-207 3.5.1.47 S Peptidase dimerisation domain
NIEPNHIF_01789 1.2e-138 S Protein of unknown function (DUF3100)
NIEPNHIF_01790 4.4e-83 S An automated process has identified a potential problem with this gene model
NIEPNHIF_01791 1.1e-49 S Uncharacterized protein conserved in bacteria (DUF2263)
NIEPNHIF_01792 1.1e-112 S SLAP domain
NIEPNHIF_01793 1.9e-88
NIEPNHIF_01794 3e-09 isdH M Iron Transport-associated domain
NIEPNHIF_01795 5.7e-124 M Iron Transport-associated domain
NIEPNHIF_01796 1.9e-158 isdE P Periplasmic binding protein
NIEPNHIF_01797 1.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIEPNHIF_01798 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
NIEPNHIF_01799 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NIEPNHIF_01800 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NIEPNHIF_01801 1.3e-38 S RelB antitoxin
NIEPNHIF_01802 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
NIEPNHIF_01803 0.0 S membrane
NIEPNHIF_01804 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NIEPNHIF_01805 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NIEPNHIF_01806 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIEPNHIF_01807 3.1e-119 gluP 3.4.21.105 S Rhomboid family
NIEPNHIF_01808 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NIEPNHIF_01809 1.5e-65 yqhL P Rhodanese-like protein
NIEPNHIF_01810 9.2e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NIEPNHIF_01811 2e-225 ynbB 4.4.1.1 P aluminum resistance
NIEPNHIF_01812 2e-263 glnA 6.3.1.2 E glutamine synthetase
NIEPNHIF_01813 3e-170
NIEPNHIF_01814 3e-147
NIEPNHIF_01815 2.1e-111 L Transposase
NIEPNHIF_01816 9e-124 L Transposase
NIEPNHIF_01817 3.8e-221 L COG3547 Transposase and inactivated derivatives
NIEPNHIF_01818 4.4e-43
NIEPNHIF_01819 1.9e-59 L COG2963 Transposase and inactivated derivatives
NIEPNHIF_01820 1.5e-274 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIEPNHIF_01821 1.1e-83 S Putative inner membrane protein (DUF1819)
NIEPNHIF_01822 2.4e-88 S Domain of unknown function (DUF1788)
NIEPNHIF_01823 1.1e-223 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
NIEPNHIF_01824 0.0 2.1.1.72 V Eco57I restriction-modification methylase
NIEPNHIF_01827 4.7e-24
NIEPNHIF_01828 1.6e-46 S Domain of unknown function (DUF4417)
NIEPNHIF_01829 3e-30 E IrrE N-terminal-like domain
NIEPNHIF_01830 3.1e-29 K Helix-turn-helix
NIEPNHIF_01831 0.0 S PglZ domain
NIEPNHIF_01832 9.9e-62 K Periplasmic binding protein-like domain
NIEPNHIF_01833 7.2e-89 K Periplasmic binding protein-like domain
NIEPNHIF_01834 5.7e-106 K Transcriptional regulator, AbiEi antitoxin
NIEPNHIF_01835 6e-26 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
NIEPNHIF_01836 4.5e-126 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
NIEPNHIF_01837 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NIEPNHIF_01838 5.9e-185 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NIEPNHIF_01839 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NIEPNHIF_01840 2.5e-186 lacR K Transcriptional regulator
NIEPNHIF_01841 0.0 lacS G Transporter
NIEPNHIF_01842 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NIEPNHIF_01843 8.1e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NIEPNHIF_01844 2.8e-287 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NIEPNHIF_01845 1.6e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NIEPNHIF_01846 5.5e-36
NIEPNHIF_01847 1.5e-159 scrR K Periplasmic binding protein domain
NIEPNHIF_01848 7.1e-239 msmE G Bacterial extracellular solute-binding protein
NIEPNHIF_01849 4.8e-157 msmF P Binding-protein-dependent transport system inner membrane component
NIEPNHIF_01850 5.2e-153 msmG P Binding-protein-dependent transport system inner membrane component
NIEPNHIF_01851 2.8e-210 msmX P Belongs to the ABC transporter superfamily
NIEPNHIF_01852 0.0 rafA 3.2.1.22 G alpha-galactosidase
NIEPNHIF_01853 4.6e-282 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NIEPNHIF_01854 1.3e-113 2.7.6.5 T Region found in RelA / SpoT proteins
NIEPNHIF_01855 3.8e-106 K response regulator
NIEPNHIF_01856 3.1e-221 sptS 2.7.13.3 T Histidine kinase
NIEPNHIF_01857 1.2e-208 EGP Major facilitator Superfamily
NIEPNHIF_01858 2.9e-69 O OsmC-like protein
NIEPNHIF_01859 4e-95 S Protein of unknown function (DUF805)
NIEPNHIF_01860 2.2e-78
NIEPNHIF_01861 8.5e-284
NIEPNHIF_01862 1.2e-137 S Fic/DOC family
NIEPNHIF_01863 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
NIEPNHIF_01864 5.7e-23
NIEPNHIF_01865 3.8e-218 KQ helix_turn_helix, mercury resistance
NIEPNHIF_01866 2.4e-208 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIEPNHIF_01867 8.2e-165 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NIEPNHIF_01868 1.8e-115 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NIEPNHIF_01869 5.9e-180 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NIEPNHIF_01870 4.5e-177 L COG2826 Transposase and inactivated derivatives, IS30 family
NIEPNHIF_01871 3.3e-166 UW LPXTG-motif cell wall anchor domain protein
NIEPNHIF_01872 9.1e-139 L COG2826 Transposase and inactivated derivatives, IS30 family
NIEPNHIF_01873 0.0 L Transposase DDE domain
NIEPNHIF_01874 6.4e-191 S SLAP domain
NIEPNHIF_01875 5.2e-38 S Protein of unknown function (DUF2922)
NIEPNHIF_01876 5.5e-30
NIEPNHIF_01877 2.8e-221 tnpB L Putative transposase DNA-binding domain
NIEPNHIF_01879 5.9e-45
NIEPNHIF_01880 3.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NIEPNHIF_01881 2.3e-10 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NIEPNHIF_01882 2.1e-45 S PFAM Archaeal ATPase
NIEPNHIF_01883 1.1e-74
NIEPNHIF_01884 0.0 kup P Transport of potassium into the cell
NIEPNHIF_01885 0.0 pepO 3.4.24.71 O Peptidase family M13
NIEPNHIF_01886 1.4e-210 yttB EGP Major facilitator Superfamily
NIEPNHIF_01887 3.4e-230 XK27_04775 S PAS domain
NIEPNHIF_01888 2.1e-103 S Iron-sulfur cluster assembly protein
NIEPNHIF_01889 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIEPNHIF_01890 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NIEPNHIF_01891 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
NIEPNHIF_01892 0.0 asnB 6.3.5.4 E Asparagine synthase
NIEPNHIF_01893 4.2e-272 S Calcineurin-like phosphoesterase
NIEPNHIF_01894 8.7e-84
NIEPNHIF_01895 3.3e-106 tag 3.2.2.20 L glycosylase
NIEPNHIF_01896 2.2e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NIEPNHIF_01897 2.8e-124 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NIEPNHIF_01898 4.1e-136 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NIEPNHIF_01899 1.2e-150 phnD P Phosphonate ABC transporter
NIEPNHIF_01900 5.2e-84 uspA T universal stress protein
NIEPNHIF_01901 2.6e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
NIEPNHIF_01902 7e-89 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIEPNHIF_01903 3.6e-90 ntd 2.4.2.6 F Nucleoside
NIEPNHIF_01905 2e-274 S Archaea bacterial proteins of unknown function
NIEPNHIF_01906 1.5e-61 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NIEPNHIF_01907 9.8e-46
NIEPNHIF_01908 1.7e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NIEPNHIF_01909 0.0 G Belongs to the glycosyl hydrolase 31 family
NIEPNHIF_01910 1.1e-150 I alpha/beta hydrolase fold
NIEPNHIF_01911 3.4e-130 yibF S overlaps another CDS with the same product name
NIEPNHIF_01912 9.1e-201 yibE S overlaps another CDS with the same product name
NIEPNHIF_01913 3.1e-112
NIEPNHIF_01914 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NIEPNHIF_01915 2.9e-224 S Cysteine-rich secretory protein family
NIEPNHIF_01916 2.3e-69 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIEPNHIF_01917 7.8e-73
NIEPNHIF_01919 2.5e-86 K DNA-templated transcription, initiation
NIEPNHIF_01920 1.5e-25
NIEPNHIF_01921 2.6e-150 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NIEPNHIF_01922 8e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NIEPNHIF_01923 5.9e-47 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
NIEPNHIF_01924 6.5e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NIEPNHIF_01925 3.7e-67 L RelB antitoxin
NIEPNHIF_01927 3.8e-133 cobQ S glutamine amidotransferase
NIEPNHIF_01928 1.6e-82 M NlpC/P60 family
NIEPNHIF_01929 1.9e-61 L COG2826 Transposase and inactivated derivatives, IS30 family
NIEPNHIF_01930 1.1e-47 L COG2826 Transposase and inactivated derivatives, IS30 family
NIEPNHIF_01932 9.8e-121 yhiD S MgtC family
NIEPNHIF_01933 2e-230 I Protein of unknown function (DUF2974)
NIEPNHIF_01934 1.4e-16
NIEPNHIF_01936 3.5e-168 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NIEPNHIF_01937 1.3e-165 degV S DegV family
NIEPNHIF_01938 1e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
NIEPNHIF_01939 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NIEPNHIF_01940 5.7e-69 rplI J Binds to the 23S rRNA
NIEPNHIF_01941 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NIEPNHIF_01942 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIEPNHIF_01943 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NIEPNHIF_01944 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
NIEPNHIF_01945 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIEPNHIF_01946 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIEPNHIF_01947 6.2e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIEPNHIF_01948 2.6e-35 yaaA S S4 domain protein YaaA
NIEPNHIF_01949 9.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIEPNHIF_01950 5.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIEPNHIF_01951 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NIEPNHIF_01952 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NIEPNHIF_01953 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIEPNHIF_01954 4.7e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NIEPNHIF_01955 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NIEPNHIF_01956 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NIEPNHIF_01957 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIEPNHIF_01958 3.3e-286 clcA P chloride
NIEPNHIF_01959 4e-32 E Zn peptidase
NIEPNHIF_01960 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_01961 1.2e-44
NIEPNHIF_01962 1.2e-191 S Bacteriocin helveticin-J
NIEPNHIF_01963 1.2e-123 S SLAP domain
NIEPNHIF_01964 1.9e-211
NIEPNHIF_01965 1.2e-18
NIEPNHIF_01966 7e-248 EGP Sugar (and other) transporter
NIEPNHIF_01967 3.7e-19
NIEPNHIF_01968 9e-47 S MazG-like family
NIEPNHIF_01969 8.7e-57
NIEPNHIF_01970 9e-22 S Protein of unknown function (DUF3923)
NIEPNHIF_01971 3.7e-132 3.1.3.48 T Tyrosine phosphatase family
NIEPNHIF_01972 8.1e-115 glsA 3.5.1.2 E Belongs to the glutaminase family
NIEPNHIF_01973 2.7e-263
NIEPNHIF_01974 9e-259 I Protein of unknown function (DUF2974)
NIEPNHIF_01975 2.3e-38 C FMN_bind
NIEPNHIF_01976 3.6e-99 M ErfK YbiS YcfS YnhG
NIEPNHIF_01977 7.4e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIEPNHIF_01978 1.7e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NIEPNHIF_01980 1.5e-44 pspC KT PspC domain
NIEPNHIF_01981 8e-299 ytgP S Polysaccharide biosynthesis protein
NIEPNHIF_01982 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIEPNHIF_01983 4.9e-122 3.6.1.27 I Acid phosphatase homologues
NIEPNHIF_01984 1.3e-168 K LysR substrate binding domain
NIEPNHIF_01985 2.1e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NIEPNHIF_01986 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
NIEPNHIF_01987 5.6e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NIEPNHIF_01988 4.4e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NIEPNHIF_01989 3.4e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NIEPNHIF_01990 5.4e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NIEPNHIF_01991 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NIEPNHIF_01992 3.3e-178 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NIEPNHIF_01993 2.3e-273 cydA 1.10.3.14 C ubiquinol oxidase
NIEPNHIF_01994 6.9e-145 ybbH_2 K rpiR family
NIEPNHIF_01995 5.8e-194 S Bacterial protein of unknown function (DUF871)
NIEPNHIF_01996 3.9e-154 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NIEPNHIF_01997 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
NIEPNHIF_01998 1.7e-260 qacA EGP Major facilitator Superfamily
NIEPNHIF_01999 4.6e-219 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIEPNHIF_02002 1.3e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
NIEPNHIF_02006 7.8e-107 M hydrolase, family 25
NIEPNHIF_02007 7.5e-36 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NIEPNHIF_02013 5.4e-71 S Calcineurin-like phosphoesterase
NIEPNHIF_02015 1.9e-13 S Prophage endopeptidase tail
NIEPNHIF_02016 7.1e-20 S Phage tail protein
NIEPNHIF_02017 1.2e-95 S peptidoglycan catabolic process
NIEPNHIF_02018 6e-29 S Bacteriophage Gp15 protein
NIEPNHIF_02020 4.4e-42 N domain, Protein
NIEPNHIF_02021 3e-13 S Minor capsid protein from bacteriophage
NIEPNHIF_02022 1.8e-23 S Minor capsid protein
NIEPNHIF_02023 1.3e-18 S Minor capsid protein
NIEPNHIF_02024 1e-24
NIEPNHIF_02025 3.2e-70 gpG
NIEPNHIF_02026 7e-22 S Phage minor structural protein GP20
NIEPNHIF_02028 1.7e-104 S Phage minor capsid protein 2
NIEPNHIF_02029 3.8e-136 S Phage portal protein, SPP1 Gp6-like
NIEPNHIF_02030 1.9e-160 S Pfam:Terminase_3C
NIEPNHIF_02034 1.3e-81 C Domain of unknown function (DUF4145)
NIEPNHIF_02035 3.7e-08
NIEPNHIF_02039 8.5e-14
NIEPNHIF_02040 2.1e-14 K transcriptional
NIEPNHIF_02041 7.3e-35 K Helix-turn-helix domain
NIEPNHIF_02042 5.9e-38 S ERF superfamily
NIEPNHIF_02043 1.1e-39 S Protein of unknown function (DUF1351)
NIEPNHIF_02044 1.5e-23
NIEPNHIF_02046 2e-08 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_02047 8.5e-08
NIEPNHIF_02048 1.8e-24 S Domain of unknown function (DUF771)
NIEPNHIF_02049 2e-22 K Helix-turn-helix XRE-family like proteins
NIEPNHIF_02050 2.7e-29 ansR 3.4.21.88 K sequence-specific DNA binding
NIEPNHIF_02051 4.8e-17 S Pfam:Peptidase_M78
NIEPNHIF_02053 1.7e-06 M LysM domain
NIEPNHIF_02055 1.1e-98
NIEPNHIF_02057 5.7e-139 L Belongs to the 'phage' integrase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)