ORF_ID e_value Gene_name EC_number CAZy COGs Description
PAKFEKLM_00001 2e-247 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PAKFEKLM_00002 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PAKFEKLM_00003 5e-37 yaaA S S4 domain protein YaaA
PAKFEKLM_00004 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PAKFEKLM_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PAKFEKLM_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PAKFEKLM_00007 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
PAKFEKLM_00008 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PAKFEKLM_00009 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PAKFEKLM_00010 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PAKFEKLM_00011 1.4e-67 rplI J Binds to the 23S rRNA
PAKFEKLM_00012 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PAKFEKLM_00013 8.8e-226 yttB EGP Major facilitator Superfamily
PAKFEKLM_00014 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PAKFEKLM_00015 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PAKFEKLM_00017 1.9e-276 E ABC transporter, substratebinding protein
PAKFEKLM_00018 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PAKFEKLM_00019 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PAKFEKLM_00020 4.1e-196 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
PAKFEKLM_00021 2.8e-279 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
PAKFEKLM_00022 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PAKFEKLM_00023 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
PAKFEKLM_00024 4.5e-143 S haloacid dehalogenase-like hydrolase
PAKFEKLM_00025 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PAKFEKLM_00026 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
PAKFEKLM_00027 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
PAKFEKLM_00028 1.6e-31 cspA K Cold shock protein domain
PAKFEKLM_00029 1.7e-37
PAKFEKLM_00031 6.2e-131 K response regulator
PAKFEKLM_00032 0.0 vicK 2.7.13.3 T Histidine kinase
PAKFEKLM_00033 2.7e-244 yycH S YycH protein
PAKFEKLM_00034 2.2e-151 yycI S YycH protein
PAKFEKLM_00035 8.9e-158 vicX 3.1.26.11 S domain protein
PAKFEKLM_00036 6.8e-173 htrA 3.4.21.107 O serine protease
PAKFEKLM_00037 2e-196 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PAKFEKLM_00038 4.7e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PAKFEKLM_00039 1.5e-95 K Bacterial regulatory proteins, tetR family
PAKFEKLM_00040 1.2e-261 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
PAKFEKLM_00041 1.5e-167 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PAKFEKLM_00042 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
PAKFEKLM_00043 9.1e-121 pnb C nitroreductase
PAKFEKLM_00044 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
PAKFEKLM_00045 1.8e-116 S Elongation factor G-binding protein, N-terminal
PAKFEKLM_00046 1.6e-157 S Protein of unknown function (DUF2785)
PAKFEKLM_00047 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
PAKFEKLM_00048 1.6e-258 P Sodium:sulfate symporter transmembrane region
PAKFEKLM_00049 5.7e-158 K LysR family
PAKFEKLM_00050 5.1e-72 C FMN binding
PAKFEKLM_00051 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAKFEKLM_00052 2e-163 ptlF S KR domain
PAKFEKLM_00053 2.4e-158 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
PAKFEKLM_00054 3.7e-122 drgA C Nitroreductase family
PAKFEKLM_00055 1.3e-290 QT PucR C-terminal helix-turn-helix domain
PAKFEKLM_00056 5.5e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PAKFEKLM_00057 7.9e-196 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PAKFEKLM_00058 7.4e-250 yjjP S Putative threonine/serine exporter
PAKFEKLM_00059 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
PAKFEKLM_00060 6.9e-254 1.14.14.9 Q 4-hydroxyphenylacetate
PAKFEKLM_00061 2.9e-81 6.3.3.2 S ASCH
PAKFEKLM_00062 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
PAKFEKLM_00063 2e-169 yobV1 K WYL domain
PAKFEKLM_00064 3.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PAKFEKLM_00065 0.0 tetP J elongation factor G
PAKFEKLM_00066 1.3e-125 S Protein of unknown function
PAKFEKLM_00067 1.6e-152 EG EamA-like transporter family
PAKFEKLM_00068 1.4e-92 MA20_25245 K FR47-like protein
PAKFEKLM_00069 2e-126 hchA S DJ-1/PfpI family
PAKFEKLM_00070 2.3e-179 1.1.1.1 C nadph quinone reductase
PAKFEKLM_00071 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
PAKFEKLM_00072 2.3e-235 mepA V MATE efflux family protein
PAKFEKLM_00073 3.8e-47 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
PAKFEKLM_00074 1.3e-139 S Belongs to the UPF0246 family
PAKFEKLM_00075 6e-76
PAKFEKLM_00076 4.7e-307 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
PAKFEKLM_00077 2.4e-141
PAKFEKLM_00079 1.3e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
PAKFEKLM_00080 4.8e-40
PAKFEKLM_00081 2.5e-127 cbiO P ABC transporter
PAKFEKLM_00082 3.8e-148 P Cobalt transport protein
PAKFEKLM_00083 4.8e-182 nikMN P PDGLE domain
PAKFEKLM_00084 4.2e-121 K Crp-like helix-turn-helix domain
PAKFEKLM_00085 2.9e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
PAKFEKLM_00086 5.3e-125 larB S AIR carboxylase
PAKFEKLM_00087 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PAKFEKLM_00088 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
PAKFEKLM_00089 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PAKFEKLM_00090 8.3e-151 larE S NAD synthase
PAKFEKLM_00091 5.5e-178 1.6.5.5 C Zinc-binding dehydrogenase
PAKFEKLM_00093 5.8e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PAKFEKLM_00094 1.6e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PAKFEKLM_00095 9.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PAKFEKLM_00096 9.9e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
PAKFEKLM_00097 4.3e-135 S peptidase C26
PAKFEKLM_00098 5.8e-302 L HIRAN domain
PAKFEKLM_00099 9.9e-85 F NUDIX domain
PAKFEKLM_00100 2.6e-250 yifK E Amino acid permease
PAKFEKLM_00101 1.7e-120
PAKFEKLM_00102 5.6e-149 ydjP I Alpha/beta hydrolase family
PAKFEKLM_00103 0.0 pacL1 P P-type ATPase
PAKFEKLM_00104 1.6e-28 KT PspC domain
PAKFEKLM_00105 1.3e-110 S NADPH-dependent FMN reductase
PAKFEKLM_00106 1.2e-74 papX3 K Transcriptional regulator
PAKFEKLM_00107 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
PAKFEKLM_00108 5.8e-82 S Protein of unknown function (DUF3021)
PAKFEKLM_00109 4.7e-227 mdtG EGP Major facilitator Superfamily
PAKFEKLM_00110 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
PAKFEKLM_00111 2.3e-215 yeaN P Transporter, major facilitator family protein
PAKFEKLM_00113 3.4e-160 S reductase
PAKFEKLM_00114 1.2e-165 1.1.1.65 C Aldo keto reductase
PAKFEKLM_00115 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
PAKFEKLM_00116 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
PAKFEKLM_00117 3.7e-47
PAKFEKLM_00118 7.8e-256
PAKFEKLM_00119 6.4e-207 C Oxidoreductase
PAKFEKLM_00120 7.1e-150 cbiQ P cobalt transport
PAKFEKLM_00121 0.0 ykoD P ABC transporter, ATP-binding protein
PAKFEKLM_00122 2.5e-98 S UPF0397 protein
PAKFEKLM_00123 3.6e-129 K UbiC transcription regulator-associated domain protein
PAKFEKLM_00124 8.3e-54 K Transcriptional regulator PadR-like family
PAKFEKLM_00125 7.8e-143
PAKFEKLM_00126 4.7e-151
PAKFEKLM_00127 9.1e-89
PAKFEKLM_00128 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
PAKFEKLM_00129 6.7e-170 yjjC V ABC transporter
PAKFEKLM_00130 7.9e-299 M Exporter of polyketide antibiotics
PAKFEKLM_00131 1.2e-115 K Transcriptional regulator
PAKFEKLM_00132 1.2e-275 C Electron transfer flavoprotein FAD-binding domain
PAKFEKLM_00133 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
PAKFEKLM_00135 1.1e-92 K Bacterial regulatory proteins, tetR family
PAKFEKLM_00136 2.8e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PAKFEKLM_00137 1.5e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PAKFEKLM_00138 1.9e-101 dhaL 2.7.1.121 S Dak2
PAKFEKLM_00139 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
PAKFEKLM_00140 5.6e-114 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PAKFEKLM_00141 1e-190 malR K Transcriptional regulator, LacI family
PAKFEKLM_00142 2e-180 yvdE K helix_turn _helix lactose operon repressor
PAKFEKLM_00143 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
PAKFEKLM_00144 1.8e-175 L Transposase and inactivated derivatives, IS30 family
PAKFEKLM_00145 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
PAKFEKLM_00146 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
PAKFEKLM_00147 1.4e-161 malD P ABC transporter permease
PAKFEKLM_00148 1.6e-149 malA S maltodextrose utilization protein MalA
PAKFEKLM_00149 1.5e-258 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
PAKFEKLM_00150 4e-209 msmK P Belongs to the ABC transporter superfamily
PAKFEKLM_00151 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PAKFEKLM_00152 0.0 3.2.1.96 G Glycosyl hydrolase family 85
PAKFEKLM_00153 3.5e-168 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PAKFEKLM_00154 0.0 rafA 3.2.1.22 G alpha-galactosidase
PAKFEKLM_00155 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
PAKFEKLM_00156 1.5e-304 scrB 3.2.1.26 GH32 G invertase
PAKFEKLM_00157 9.1e-173 scrR K Transcriptional regulator, LacI family
PAKFEKLM_00158 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PAKFEKLM_00159 1.3e-165 3.5.1.10 C nadph quinone reductase
PAKFEKLM_00160 2.5e-217 nhaC C Na H antiporter NhaC
PAKFEKLM_00161 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PAKFEKLM_00162 7.7e-166 mleR K LysR substrate binding domain
PAKFEKLM_00163 0.0 3.6.4.13 M domain protein
PAKFEKLM_00165 1e-156 hipB K Helix-turn-helix
PAKFEKLM_00166 0.0 oppA E ABC transporter, substratebinding protein
PAKFEKLM_00167 1.8e-309 oppA E ABC transporter, substratebinding protein
PAKFEKLM_00168 1.6e-174 L Transposase and inactivated derivatives, IS30 family
PAKFEKLM_00169 3e-73 yiaC K Acetyltransferase (GNAT) domain
PAKFEKLM_00170 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAKFEKLM_00171 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PAKFEKLM_00172 3e-113 pgm1 G phosphoglycerate mutase
PAKFEKLM_00173 2.9e-179 yghZ C Aldo keto reductase family protein
PAKFEKLM_00174 4.9e-34
PAKFEKLM_00175 1.8e-11 S Domain of unknown function (DU1801)
PAKFEKLM_00176 4e-164 FbpA K Domain of unknown function (DUF814)
PAKFEKLM_00177 1.7e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PAKFEKLM_00179 4.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAKFEKLM_00180 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAKFEKLM_00181 4.7e-261 S ATPases associated with a variety of cellular activities
PAKFEKLM_00182 1.8e-116 P cobalt transport
PAKFEKLM_00183 2e-258 P ABC transporter
PAKFEKLM_00184 3.1e-101 S ABC transporter permease
PAKFEKLM_00185 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PAKFEKLM_00186 4.1e-158 dkgB S reductase
PAKFEKLM_00187 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PAKFEKLM_00188 2.4e-66
PAKFEKLM_00189 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PAKFEKLM_00190 1e-173 P Major Facilitator Superfamily
PAKFEKLM_00191 2.7e-224 1.3.5.4 C FAD dependent oxidoreductase
PAKFEKLM_00192 3.1e-98 K Helix-turn-helix domain
PAKFEKLM_00193 2.6e-277 pipD E Dipeptidase
PAKFEKLM_00194 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
PAKFEKLM_00195 0.0 mtlR K Mga helix-turn-helix domain
PAKFEKLM_00196 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_00197 6.2e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
PAKFEKLM_00198 2.9e-75
PAKFEKLM_00199 6.2e-57 trxA1 O Belongs to the thioredoxin family
PAKFEKLM_00200 1.2e-49
PAKFEKLM_00201 2.5e-95
PAKFEKLM_00202 3.8e-61
PAKFEKLM_00203 3.9e-81 ndk 2.7.4.6 F Belongs to the NDK family
PAKFEKLM_00204 9.9e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
PAKFEKLM_00205 3.5e-97 yieF S NADPH-dependent FMN reductase
PAKFEKLM_00206 2.7e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
PAKFEKLM_00207 4.9e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PAKFEKLM_00208 2.2e-165 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PAKFEKLM_00209 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
PAKFEKLM_00210 9.5e-141 pnuC H nicotinamide mononucleotide transporter
PAKFEKLM_00211 7.3e-43 S Protein of unknown function (DUF2089)
PAKFEKLM_00212 3.7e-42
PAKFEKLM_00213 3.5e-129 treR K UTRA
PAKFEKLM_00214 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
PAKFEKLM_00215 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PAKFEKLM_00216 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
PAKFEKLM_00217 1.4e-144
PAKFEKLM_00218 6.3e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PAKFEKLM_00219 1.6e-70
PAKFEKLM_00220 1.8e-72 K Transcriptional regulator
PAKFEKLM_00221 3.7e-120 K Bacterial regulatory proteins, tetR family
PAKFEKLM_00222 2.5e-232 mntH P H( )-stimulated, divalent metal cation uptake system
PAKFEKLM_00223 5.5e-118
PAKFEKLM_00224 5.2e-42
PAKFEKLM_00225 4e-40
PAKFEKLM_00226 1.5e-250 ydiC1 EGP Major facilitator Superfamily
PAKFEKLM_00227 9.5e-65 K helix_turn_helix, mercury resistance
PAKFEKLM_00228 2.3e-251 T PhoQ Sensor
PAKFEKLM_00229 1.3e-128 K Transcriptional regulatory protein, C terminal
PAKFEKLM_00230 1.8e-49
PAKFEKLM_00231 2.1e-129 yidA K Helix-turn-helix domain, rpiR family
PAKFEKLM_00232 7.8e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_00233 9.9e-57
PAKFEKLM_00234 2.1e-41
PAKFEKLM_00235 2e-183 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PAKFEKLM_00236 2.6e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
PAKFEKLM_00237 1.3e-47
PAKFEKLM_00238 2.7e-123 2.7.6.5 S RelA SpoT domain protein
PAKFEKLM_00239 3.1e-104 K transcriptional regulator
PAKFEKLM_00240 0.0 ydgH S MMPL family
PAKFEKLM_00241 1e-107 tag 3.2.2.20 L glycosylase
PAKFEKLM_00242 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
PAKFEKLM_00243 2.4e-193 yclI V MacB-like periplasmic core domain
PAKFEKLM_00244 7.1e-121 yclH V ABC transporter
PAKFEKLM_00245 2.5e-114 V CAAX protease self-immunity
PAKFEKLM_00246 1.2e-110 S CAAX protease self-immunity
PAKFEKLM_00247 1.7e-52 M Lysin motif
PAKFEKLM_00248 1.2e-37 lytE M LysM domain protein
PAKFEKLM_00249 1.8e-65 gcvH E Glycine cleavage H-protein
PAKFEKLM_00250 1.1e-177 sepS16B
PAKFEKLM_00251 3.7e-131
PAKFEKLM_00252 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
PAKFEKLM_00253 2.2e-55
PAKFEKLM_00254 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PAKFEKLM_00255 6.5e-78 elaA S GNAT family
PAKFEKLM_00256 1.7e-75 K Transcriptional regulator
PAKFEKLM_00257 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
PAKFEKLM_00258 4.3e-40
PAKFEKLM_00259 2.6e-205 potD P ABC transporter
PAKFEKLM_00260 1.7e-140 potC P ABC transporter permease
PAKFEKLM_00261 2e-149 potB P ABC transporter permease
PAKFEKLM_00262 1.2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PAKFEKLM_00263 5e-96 puuR K Cupin domain
PAKFEKLM_00264 2.4e-83 6.3.3.2 S ASCH
PAKFEKLM_00265 1e-84 K GNAT family
PAKFEKLM_00266 1.8e-90 K acetyltransferase
PAKFEKLM_00267 8.1e-22
PAKFEKLM_00268 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
PAKFEKLM_00269 2e-163 ytrB V ABC transporter
PAKFEKLM_00270 1.5e-175
PAKFEKLM_00271 9.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
PAKFEKLM_00272 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PAKFEKLM_00274 2.3e-240 xylP1 G MFS/sugar transport protein
PAKFEKLM_00275 3e-122 qmcA O prohibitin homologues
PAKFEKLM_00276 1.1e-29
PAKFEKLM_00277 1.7e-281 pipD E Dipeptidase
PAKFEKLM_00278 3e-40
PAKFEKLM_00279 6.8e-96 bioY S BioY family
PAKFEKLM_00280 1.4e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PAKFEKLM_00281 2.8e-60 S CHY zinc finger
PAKFEKLM_00282 4.5e-112 metQ P NLPA lipoprotein
PAKFEKLM_00283 8.7e-126 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PAKFEKLM_00284 1.1e-86 metI U Binding-protein-dependent transport system inner membrane component
PAKFEKLM_00285 7.7e-148 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAKFEKLM_00286 6.1e-224 mtnE 2.6.1.83 E Aminotransferase
PAKFEKLM_00287 3.8e-218
PAKFEKLM_00288 3.5e-154 tagG U Transport permease protein
PAKFEKLM_00289 3e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PAKFEKLM_00290 1.1e-43
PAKFEKLM_00291 9.8e-86 K Transcriptional regulator PadR-like family
PAKFEKLM_00292 1.1e-256 P Major Facilitator Superfamily
PAKFEKLM_00293 4.7e-241 amtB P ammonium transporter
PAKFEKLM_00294 5.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PAKFEKLM_00295 3.7e-44
PAKFEKLM_00296 6.3e-102 zmp1 O Zinc-dependent metalloprotease
PAKFEKLM_00297 7.2e-121 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
PAKFEKLM_00298 1.5e-310 mco Q Multicopper oxidase
PAKFEKLM_00299 3.2e-54 ypaA S Protein of unknown function (DUF1304)
PAKFEKLM_00300 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
PAKFEKLM_00301 4.7e-232 flhF N Uncharacterized conserved protein (DUF2075)
PAKFEKLM_00302 1.6e-82 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
PAKFEKLM_00303 9.3e-80
PAKFEKLM_00304 1.9e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PAKFEKLM_00305 2.2e-173 rihC 3.2.2.1 F Nucleoside
PAKFEKLM_00306 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
PAKFEKLM_00307 0.0
PAKFEKLM_00308 6.5e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
PAKFEKLM_00309 1.8e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PAKFEKLM_00310 9.9e-180 proV E ABC transporter, ATP-binding protein
PAKFEKLM_00311 9.8e-255 gshR 1.8.1.7 C Pyridine nucleotide-disulphide oxidoreductase
PAKFEKLM_00312 8.7e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PAKFEKLM_00313 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
PAKFEKLM_00314 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PAKFEKLM_00315 0.0 M domain protein
PAKFEKLM_00316 1e-31 M dTDP-4-dehydrorhamnose reductase activity
PAKFEKLM_00317 2.1e-54 ankB S ankyrin repeats
PAKFEKLM_00318 5.6e-37
PAKFEKLM_00319 2.4e-38
PAKFEKLM_00320 1.4e-118 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PAKFEKLM_00321 1.1e-196 uhpT EGP Major facilitator Superfamily
PAKFEKLM_00322 1.2e-146 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
PAKFEKLM_00323 1.6e-165 K Transcriptional regulator
PAKFEKLM_00324 3.2e-80 S hydrolase
PAKFEKLM_00325 2.5e-43 S hydrolase
PAKFEKLM_00326 3.2e-256 brnQ U Component of the transport system for branched-chain amino acids
PAKFEKLM_00327 2.8e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PAKFEKLM_00328 5.4e-26
PAKFEKLM_00329 6.3e-221 L Transposase
PAKFEKLM_00331 8.2e-92 2.7.13.3 T GHKL domain
PAKFEKLM_00332 2.5e-130 plnD K LytTr DNA-binding domain
PAKFEKLM_00333 6.3e-129 S CAAX protease self-immunity
PAKFEKLM_00334 3.1e-22 plnF
PAKFEKLM_00335 6.7e-23
PAKFEKLM_00336 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PAKFEKLM_00337 7.9e-35 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PAKFEKLM_00338 4.9e-241 mesE M Transport protein ComB
PAKFEKLM_00339 1e-109 S CAAX protease self-immunity
PAKFEKLM_00340 2e-118 ypbD S CAAX protease self-immunity
PAKFEKLM_00341 9.9e-110 V CAAX protease self-immunity
PAKFEKLM_00342 6.1e-112 S CAAX protease self-immunity
PAKFEKLM_00343 6.9e-36 S RelE-like toxin of type II toxin-antitoxin system HigB
PAKFEKLM_00344 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
PAKFEKLM_00345 0.0 helD 3.6.4.12 L DNA helicase
PAKFEKLM_00346 3.2e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PAKFEKLM_00347 1.7e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PAKFEKLM_00348 1.5e-129 K UbiC transcription regulator-associated domain protein
PAKFEKLM_00349 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_00350 3.9e-24
PAKFEKLM_00351 2.6e-76 S Domain of unknown function (DUF3284)
PAKFEKLM_00352 1.5e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_00353 7.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PAKFEKLM_00354 2e-163 GK ROK family
PAKFEKLM_00355 8.5e-131 K Helix-turn-helix domain, rpiR family
PAKFEKLM_00356 1.8e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PAKFEKLM_00357 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PAKFEKLM_00358 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PAKFEKLM_00359 5e-176
PAKFEKLM_00360 1.8e-130 cobB K SIR2 family
PAKFEKLM_00361 8.4e-159 yunF F Protein of unknown function DUF72
PAKFEKLM_00362 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
PAKFEKLM_00363 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PAKFEKLM_00364 1.8e-212 bcr1 EGP Major facilitator Superfamily
PAKFEKLM_00365 3e-106 mutR K sequence-specific DNA binding
PAKFEKLM_00367 1.5e-146 tatD L hydrolase, TatD family
PAKFEKLM_00368 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PAKFEKLM_00369 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PAKFEKLM_00370 3.2e-37 veg S Biofilm formation stimulator VEG
PAKFEKLM_00371 1.3e-162 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PAKFEKLM_00372 1.1e-180 S Prolyl oligopeptidase family
PAKFEKLM_00373 9.8e-129 fhuC 3.6.3.35 P ABC transporter
PAKFEKLM_00374 9.2e-131 znuB U ABC 3 transport family
PAKFEKLM_00375 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PAKFEKLM_00376 1.2e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PAKFEKLM_00377 7.4e-152 bla1 3.5.2.6 V Beta-lactamase enzyme family
PAKFEKLM_00378 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PAKFEKLM_00379 2.5e-181 S DUF218 domain
PAKFEKLM_00380 4.1e-125
PAKFEKLM_00381 1.7e-148 yxeH S hydrolase
PAKFEKLM_00382 9e-264 ywfO S HD domain protein
PAKFEKLM_00383 1.8e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
PAKFEKLM_00384 3.8e-78 ywiB S Domain of unknown function (DUF1934)
PAKFEKLM_00385 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PAKFEKLM_00386 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PAKFEKLM_00387 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PAKFEKLM_00388 3.1e-229 tdcC E amino acid
PAKFEKLM_00389 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PAKFEKLM_00390 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PAKFEKLM_00391 6.4e-131 S YheO-like PAS domain
PAKFEKLM_00392 2.5e-26
PAKFEKLM_00393 1.8e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PAKFEKLM_00394 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PAKFEKLM_00395 7.8e-41 rpmE2 J Ribosomal protein L31
PAKFEKLM_00396 3.2e-214 J translation release factor activity
PAKFEKLM_00397 6e-126 srtA 3.4.22.70 M sortase family
PAKFEKLM_00398 1.7e-91 lemA S LemA family
PAKFEKLM_00399 1e-138 htpX O Belongs to the peptidase M48B family
PAKFEKLM_00400 2e-146
PAKFEKLM_00401 5.6e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PAKFEKLM_00402 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PAKFEKLM_00403 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PAKFEKLM_00404 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PAKFEKLM_00405 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
PAKFEKLM_00406 0.0 kup P Transport of potassium into the cell
PAKFEKLM_00407 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PAKFEKLM_00408 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PAKFEKLM_00409 8e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PAKFEKLM_00410 6.9e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PAKFEKLM_00411 1e-128 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
PAKFEKLM_00412 1.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
PAKFEKLM_00413 2.7e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PAKFEKLM_00414 4.1e-84 S QueT transporter
PAKFEKLM_00415 2.1e-114 S (CBS) domain
PAKFEKLM_00416 2.4e-264 S Putative peptidoglycan binding domain
PAKFEKLM_00417 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PAKFEKLM_00418 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PAKFEKLM_00419 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PAKFEKLM_00420 7.3e-289 yabM S Polysaccharide biosynthesis protein
PAKFEKLM_00421 2.2e-42 yabO J S4 domain protein
PAKFEKLM_00423 1.1e-63 divIC D Septum formation initiator
PAKFEKLM_00424 3.1e-74 yabR J RNA binding
PAKFEKLM_00425 6.9e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PAKFEKLM_00426 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PAKFEKLM_00427 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PAKFEKLM_00428 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PAKFEKLM_00429 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PAKFEKLM_00430 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PAKFEKLM_00433 1.5e-42 S COG NOG38524 non supervised orthologous group
PAKFEKLM_00436 3e-252 dtpT U amino acid peptide transporter
PAKFEKLM_00437 2e-151 yjjH S Calcineurin-like phosphoesterase
PAKFEKLM_00440 1.5e-179 sip L Belongs to the 'phage' integrase family
PAKFEKLM_00443 2e-118 S Phage regulatory protein Rha (Phage_pRha)
PAKFEKLM_00444 6.4e-38
PAKFEKLM_00447 3.1e-21
PAKFEKLM_00448 5.1e-31
PAKFEKLM_00449 1.2e-132 L Primase C terminal 1 (PriCT-1)
PAKFEKLM_00450 1.8e-262 S Virulence-associated protein E
PAKFEKLM_00451 1.7e-63
PAKFEKLM_00452 7.4e-68
PAKFEKLM_00454 3.3e-47
PAKFEKLM_00457 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
PAKFEKLM_00458 2.5e-53 S Cupin domain
PAKFEKLM_00459 4.9e-167 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
PAKFEKLM_00460 1.2e-192 ybiR P Citrate transporter
PAKFEKLM_00461 3.7e-151 pnuC H nicotinamide mononucleotide transporter
PAKFEKLM_00462 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAKFEKLM_00463 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PAKFEKLM_00464 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
PAKFEKLM_00465 1.2e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PAKFEKLM_00466 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PAKFEKLM_00467 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PAKFEKLM_00468 0.0 pacL 3.6.3.8 P P-type ATPase
PAKFEKLM_00469 8.9e-72
PAKFEKLM_00470 0.0 yhgF K Tex-like protein N-terminal domain protein
PAKFEKLM_00471 1.2e-82 ydcK S Belongs to the SprT family
PAKFEKLM_00472 7.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PAKFEKLM_00473 6.4e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PAKFEKLM_00475 2.8e-151 G Peptidase_C39 like family
PAKFEKLM_00476 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PAKFEKLM_00477 1.1e-131 manY G PTS system
PAKFEKLM_00478 4.4e-169 manN G system, mannose fructose sorbose family IID component
PAKFEKLM_00479 4.7e-64 S Domain of unknown function (DUF956)
PAKFEKLM_00480 0.0 levR K Sigma-54 interaction domain
PAKFEKLM_00481 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
PAKFEKLM_00482 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
PAKFEKLM_00483 7.8e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAKFEKLM_00484 2.2e-64 accB 2.3.1.12 I Biotin-requiring enzyme
PAKFEKLM_00485 1.2e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
PAKFEKLM_00486 3.7e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PAKFEKLM_00487 4.1e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
PAKFEKLM_00488 4.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PAKFEKLM_00489 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PAKFEKLM_00490 8.3e-177 EG EamA-like transporter family
PAKFEKLM_00491 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PAKFEKLM_00492 5.2e-113 zmp2 O Zinc-dependent metalloprotease
PAKFEKLM_00493 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
PAKFEKLM_00494 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PAKFEKLM_00495 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
PAKFEKLM_00496 1.1e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PAKFEKLM_00497 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PAKFEKLM_00498 1.4e-204 yacL S domain protein
PAKFEKLM_00499 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PAKFEKLM_00500 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PAKFEKLM_00501 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PAKFEKLM_00502 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PAKFEKLM_00503 5.3e-98 yacP S YacP-like NYN domain
PAKFEKLM_00504 3e-81 sigH K Sigma-70 region 2
PAKFEKLM_00505 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PAKFEKLM_00506 3.4e-28 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PAKFEKLM_00507 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
PAKFEKLM_00508 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
PAKFEKLM_00509 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PAKFEKLM_00510 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PAKFEKLM_00511 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PAKFEKLM_00512 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PAKFEKLM_00513 4.6e-177 F DNA/RNA non-specific endonuclease
PAKFEKLM_00514 1.2e-38 L nuclease
PAKFEKLM_00515 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PAKFEKLM_00516 2.1e-40 K Helix-turn-helix domain
PAKFEKLM_00517 2.1e-108 yvdD 3.2.2.10 S Belongs to the LOG family
PAKFEKLM_00518 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAKFEKLM_00519 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAKFEKLM_00520 6.5e-37 nrdH O Glutaredoxin
PAKFEKLM_00521 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
PAKFEKLM_00522 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PAKFEKLM_00523 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PAKFEKLM_00524 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PAKFEKLM_00525 6.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PAKFEKLM_00526 2.2e-38 yaaL S Protein of unknown function (DUF2508)
PAKFEKLM_00527 1.5e-238 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PAKFEKLM_00528 1.1e-50 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PAKFEKLM_00529 1.1e-40 ulaB_1 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
PAKFEKLM_00530 3.3e-220 ulaA 2.7.1.194 S PTS system sugar-specific permease component
PAKFEKLM_00531 2.5e-99 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
PAKFEKLM_00532 8.7e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PAKFEKLM_00533 2.4e-53 yaaQ S Cyclic-di-AMP receptor
PAKFEKLM_00534 3.3e-186 holB 2.7.7.7 L DNA polymerase III
PAKFEKLM_00535 1e-57 yabA L Involved in initiation control of chromosome replication
PAKFEKLM_00536 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PAKFEKLM_00537 1.1e-147 fat 3.1.2.21 I Acyl-ACP thioesterase
PAKFEKLM_00538 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PAKFEKLM_00539 1.5e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
PAKFEKLM_00540 8.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
PAKFEKLM_00541 8.5e-143 phnE1 3.6.1.63 U ABC transporter permease
PAKFEKLM_00542 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
PAKFEKLM_00543 6.3e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PAKFEKLM_00544 5.1e-190 phnD P Phosphonate ABC transporter
PAKFEKLM_00545 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PAKFEKLM_00546 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PAKFEKLM_00547 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PAKFEKLM_00548 5.8e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PAKFEKLM_00549 2.8e-306 uup S ABC transporter, ATP-binding protein
PAKFEKLM_00550 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PAKFEKLM_00551 6.1e-109 ydiL S CAAX protease self-immunity
PAKFEKLM_00552 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PAKFEKLM_00553 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PAKFEKLM_00554 0.0 ydaO E amino acid
PAKFEKLM_00555 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
PAKFEKLM_00556 1.6e-144 pstS P Phosphate
PAKFEKLM_00557 1.7e-114 yvyE 3.4.13.9 S YigZ family
PAKFEKLM_00558 1.1e-256 comFA L Helicase C-terminal domain protein
PAKFEKLM_00559 7.5e-126 comFC S Competence protein
PAKFEKLM_00560 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PAKFEKLM_00561 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PAKFEKLM_00562 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PAKFEKLM_00563 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
PAKFEKLM_00564 1.5e-132 K response regulator
PAKFEKLM_00565 4.3e-248 phoR 2.7.13.3 T Histidine kinase
PAKFEKLM_00566 1.1e-150 pstS P Phosphate
PAKFEKLM_00567 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
PAKFEKLM_00568 1.5e-155 pstA P Phosphate transport system permease protein PstA
PAKFEKLM_00569 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PAKFEKLM_00570 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PAKFEKLM_00571 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
PAKFEKLM_00572 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
PAKFEKLM_00573 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PAKFEKLM_00574 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PAKFEKLM_00575 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PAKFEKLM_00576 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PAKFEKLM_00577 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PAKFEKLM_00578 1.9e-124 yliE T Putative diguanylate phosphodiesterase
PAKFEKLM_00579 6.7e-270 nox C NADH oxidase
PAKFEKLM_00580 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PAKFEKLM_00581 2e-109 yviA S Protein of unknown function (DUF421)
PAKFEKLM_00582 2.9e-42 S Protein of unknown function (DUF3290)
PAKFEKLM_00583 6.7e-19 S Protein of unknown function (DUF3290)
PAKFEKLM_00584 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PAKFEKLM_00585 9.6e-132 yliE T Putative diguanylate phosphodiesterase
PAKFEKLM_00586 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PAKFEKLM_00587 2.5e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
PAKFEKLM_00588 9.2e-212 norA EGP Major facilitator Superfamily
PAKFEKLM_00589 3.6e-117 yfbR S HD containing hydrolase-like enzyme
PAKFEKLM_00590 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PAKFEKLM_00591 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PAKFEKLM_00592 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PAKFEKLM_00593 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PAKFEKLM_00594 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
PAKFEKLM_00595 9.3e-87 S Short repeat of unknown function (DUF308)
PAKFEKLM_00596 1.6e-160 rapZ S Displays ATPase and GTPase activities
PAKFEKLM_00597 1.2e-188 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PAKFEKLM_00598 3.7e-168 whiA K May be required for sporulation
PAKFEKLM_00599 8.9e-306 oppA E ABC transporter, substratebinding protein
PAKFEKLM_00600 5.1e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAKFEKLM_00601 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PAKFEKLM_00603 9.3e-245 rpoN K Sigma-54 factor, core binding domain
PAKFEKLM_00604 7.3e-189 cggR K Putative sugar-binding domain
PAKFEKLM_00605 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PAKFEKLM_00606 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PAKFEKLM_00607 6.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PAKFEKLM_00608 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PAKFEKLM_00609 4.8e-133
PAKFEKLM_00610 6.6e-295 clcA P chloride
PAKFEKLM_00611 1.2e-30 secG U Preprotein translocase
PAKFEKLM_00612 8.5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
PAKFEKLM_00613 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PAKFEKLM_00614 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PAKFEKLM_00615 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
PAKFEKLM_00616 1.5e-256 glnP P ABC transporter
PAKFEKLM_00617 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PAKFEKLM_00618 6.1e-105 yxjI
PAKFEKLM_00619 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
PAKFEKLM_00620 6.3e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PAKFEKLM_00621 4.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PAKFEKLM_00622 1.5e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PAKFEKLM_00623 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
PAKFEKLM_00624 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
PAKFEKLM_00625 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
PAKFEKLM_00626 1.2e-160 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
PAKFEKLM_00627 6.2e-168 murB 1.3.1.98 M Cell wall formation
PAKFEKLM_00628 0.0 yjcE P Sodium proton antiporter
PAKFEKLM_00629 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
PAKFEKLM_00630 7.1e-121 S Protein of unknown function (DUF1361)
PAKFEKLM_00631 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PAKFEKLM_00632 1.6e-129 ybbR S YbbR-like protein
PAKFEKLM_00633 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PAKFEKLM_00634 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PAKFEKLM_00635 4.5e-123 yliE T EAL domain
PAKFEKLM_00636 1.7e-145 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
PAKFEKLM_00637 3.1e-104 K Bacterial regulatory proteins, tetR family
PAKFEKLM_00638 3.1e-71 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PAKFEKLM_00639 3.8e-104 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PAKFEKLM_00640 3.3e-52
PAKFEKLM_00641 3e-72
PAKFEKLM_00642 8.6e-131 1.5.1.39 C nitroreductase
PAKFEKLM_00643 4e-154 G Transmembrane secretion effector
PAKFEKLM_00644 4.5e-191 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PAKFEKLM_00645 4e-29 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_00646 9.8e-38 tnp2PF3 L Transposase DDE domain
PAKFEKLM_00647 1.5e-77 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PAKFEKLM_00648 8.6e-142
PAKFEKLM_00650 1.9e-71 spxA 1.20.4.1 P ArsC family
PAKFEKLM_00651 1.5e-33
PAKFEKLM_00652 3.2e-89 V VanZ like family
PAKFEKLM_00653 2.3e-241 EGP Major facilitator Superfamily
PAKFEKLM_00654 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PAKFEKLM_00655 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PAKFEKLM_00656 7e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PAKFEKLM_00657 1.5e-152 licD M LicD family
PAKFEKLM_00658 1.3e-82 K Transcriptional regulator
PAKFEKLM_00659 1.5e-19
PAKFEKLM_00660 1.2e-225 pbuG S permease
PAKFEKLM_00661 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PAKFEKLM_00662 5.3e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PAKFEKLM_00663 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PAKFEKLM_00664 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
PAKFEKLM_00665 3.5e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PAKFEKLM_00666 0.0 oatA I Acyltransferase
PAKFEKLM_00667 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PAKFEKLM_00668 7.3e-68 O OsmC-like protein
PAKFEKLM_00669 5.8e-46
PAKFEKLM_00670 1.5e-250 yfnA E Amino Acid
PAKFEKLM_00671 2.5e-88
PAKFEKLM_00672 1.9e-147 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PAKFEKLM_00673 3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
PAKFEKLM_00674 1.8e-19
PAKFEKLM_00675 6.3e-105 gmk2 2.7.4.8 F Guanylate kinase
PAKFEKLM_00676 1.3e-81 zur P Belongs to the Fur family
PAKFEKLM_00677 7.1e-12 3.2.1.14 GH18
PAKFEKLM_00678 2.4e-147
PAKFEKLM_00679 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
PAKFEKLM_00680 5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PAKFEKLM_00681 4.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAKFEKLM_00682 3.6e-41
PAKFEKLM_00684 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PAKFEKLM_00685 7.8e-149 glnH ET ABC transporter substrate-binding protein
PAKFEKLM_00686 4.6e-109 gluC P ABC transporter permease
PAKFEKLM_00687 4e-108 glnP P ABC transporter permease
PAKFEKLM_00688 2.3e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PAKFEKLM_00689 8.1e-154 K CAT RNA binding domain
PAKFEKLM_00690 7.9e-258 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
PAKFEKLM_00691 3.7e-142 G YdjC-like protein
PAKFEKLM_00692 8.3e-246 steT E amino acid
PAKFEKLM_00693 5.7e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
PAKFEKLM_00694 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
PAKFEKLM_00695 2.8e-70 K MarR family
PAKFEKLM_00696 6.4e-210 EGP Major facilitator Superfamily
PAKFEKLM_00697 3.8e-85 S membrane transporter protein
PAKFEKLM_00698 1.6e-94 K Bacterial regulatory proteins, tetR family
PAKFEKLM_00699 1.9e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PAKFEKLM_00700 2.9e-78 3.6.1.55 F NUDIX domain
PAKFEKLM_00701 1.3e-48 sugE U Multidrug resistance protein
PAKFEKLM_00702 1.2e-26
PAKFEKLM_00703 2.1e-128 pgm3 G Phosphoglycerate mutase family
PAKFEKLM_00704 4.7e-125 pgm3 G Phosphoglycerate mutase family
PAKFEKLM_00705 0.0 yjbQ P TrkA C-terminal domain protein
PAKFEKLM_00706 1.6e-177 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
PAKFEKLM_00707 9.2e-158 bglG3 K CAT RNA binding domain
PAKFEKLM_00708 0.0 2.7.1.193, 2.7.1.211 G phosphotransferase system
PAKFEKLM_00709 2.5e-299 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PAKFEKLM_00710 1.4e-110 dedA S SNARE associated Golgi protein
PAKFEKLM_00711 0.0 helD 3.6.4.12 L DNA helicase
PAKFEKLM_00712 3.3e-93 fabK 1.3.1.9 S Nitronate monooxygenase
PAKFEKLM_00713 6.1e-61 fabK 1.3.1.9 S Nitronate monooxygenase
PAKFEKLM_00714 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
PAKFEKLM_00715 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PAKFEKLM_00716 6.2e-50
PAKFEKLM_00717 4.9e-63 K Helix-turn-helix XRE-family like proteins
PAKFEKLM_00718 0.0 L AAA domain
PAKFEKLM_00719 2.5e-225 L AAA domain
PAKFEKLM_00720 1.1e-116 XK27_07075 V CAAX protease self-immunity
PAKFEKLM_00721 3.8e-57 hxlR K HxlR-like helix-turn-helix
PAKFEKLM_00722 3.2e-234 EGP Major facilitator Superfamily
PAKFEKLM_00723 1.2e-160 S Cysteine-rich secretory protein family
PAKFEKLM_00724 2.9e-48 K Cro/C1-type HTH DNA-binding domain
PAKFEKLM_00725 1e-146 S Domain of unknown function (DUF4767)
PAKFEKLM_00726 1.9e-48
PAKFEKLM_00727 5.7e-38 S MORN repeat
PAKFEKLM_00728 0.0 XK27_09800 I Acyltransferase family
PAKFEKLM_00729 7.1e-37 S Transglycosylase associated protein
PAKFEKLM_00730 2.6e-84
PAKFEKLM_00731 7.2e-23
PAKFEKLM_00732 8.7e-72 asp S Asp23 family, cell envelope-related function
PAKFEKLM_00733 8.7e-67 asp2 S Asp23 family, cell envelope-related function
PAKFEKLM_00734 1.8e-147 Q Fumarylacetoacetate (FAA) hydrolase family
PAKFEKLM_00735 7.4e-162 yjdB S Domain of unknown function (DUF4767)
PAKFEKLM_00736 5.3e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PAKFEKLM_00737 9.6e-148 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PAKFEKLM_00738 2.9e-65 S Putative inner membrane protein (DUF1819)
PAKFEKLM_00739 4.1e-72 S Domain of unknown function (DUF1788)
PAKFEKLM_00740 1.1e-195 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
PAKFEKLM_00741 6.3e-221 L Transposase
PAKFEKLM_00742 2.2e-162 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
PAKFEKLM_00743 7.8e-151 2.1.1.72 LV Eco57I restriction-modification methylase
PAKFEKLM_00744 5.9e-149 L Belongs to the 'phage' integrase family
PAKFEKLM_00745 2.2e-211 2.1.1.72 LV Eco57I restriction-modification methylase
PAKFEKLM_00746 2.4e-230 S PglZ domain
PAKFEKLM_00747 0.0 pepN 3.4.11.2 E aminopeptidase
PAKFEKLM_00749 1.6e-82 N Uncharacterized conserved protein (DUF2075)
PAKFEKLM_00750 3.5e-53 L Helix-turn-helix domain
PAKFEKLM_00751 1.7e-88 L PFAM Integrase catalytic region
PAKFEKLM_00752 1e-17
PAKFEKLM_00753 8.9e-90 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
PAKFEKLM_00754 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
PAKFEKLM_00756 3.5e-88 S AAA domain
PAKFEKLM_00757 4.5e-140 K sequence-specific DNA binding
PAKFEKLM_00758 8.6e-96 K Helix-turn-helix domain
PAKFEKLM_00759 2.9e-165 K Transcriptional regulator
PAKFEKLM_00760 5.5e-208 1.3.5.4 C FMN_bind
PAKFEKLM_00761 1.7e-134 1.3.5.4 C FMN_bind
PAKFEKLM_00763 2.3e-81 rmaD K Transcriptional regulator
PAKFEKLM_00764 1.5e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PAKFEKLM_00765 3.1e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PAKFEKLM_00766 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
PAKFEKLM_00767 6.7e-278 pipD E Dipeptidase
PAKFEKLM_00768 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PAKFEKLM_00769 8.5e-41
PAKFEKLM_00770 4.1e-32 L leucine-zipper of insertion element IS481
PAKFEKLM_00771 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PAKFEKLM_00772 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PAKFEKLM_00773 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
PAKFEKLM_00774 5.6e-138 S NADPH-dependent FMN reductase
PAKFEKLM_00775 2.3e-179
PAKFEKLM_00776 1.8e-218 yibE S overlaps another CDS with the same product name
PAKFEKLM_00777 3.4e-127 yibF S overlaps another CDS with the same product name
PAKFEKLM_00778 7.5e-103 3.2.2.20 K FR47-like protein
PAKFEKLM_00779 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PAKFEKLM_00780 5.6e-49
PAKFEKLM_00781 2.9e-190 nlhH_1 I alpha/beta hydrolase fold
PAKFEKLM_00782 5.1e-254 xylP2 G symporter
PAKFEKLM_00783 5.2e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PAKFEKLM_00784 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
PAKFEKLM_00785 0.0 asnB 6.3.5.4 E Asparagine synthase
PAKFEKLM_00786 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
PAKFEKLM_00787 5.2e-96 azlC E branched-chain amino acid
PAKFEKLM_00788 4.4e-13 azlC E branched-chain amino acid
PAKFEKLM_00789 4.4e-35 yyaN K MerR HTH family regulatory protein
PAKFEKLM_00791 2.2e-106
PAKFEKLM_00792 1.4e-117 S Domain of unknown function (DUF4811)
PAKFEKLM_00793 7e-270 lmrB EGP Major facilitator Superfamily
PAKFEKLM_00794 1.7e-84 merR K MerR HTH family regulatory protein
PAKFEKLM_00795 5.8e-58
PAKFEKLM_00796 2e-120 sirR K iron dependent repressor
PAKFEKLM_00797 6e-31 cspC K Cold shock protein
PAKFEKLM_00798 1.5e-130 thrE S Putative threonine/serine exporter
PAKFEKLM_00799 5.3e-75 S Threonine/Serine exporter, ThrE
PAKFEKLM_00800 3.3e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PAKFEKLM_00801 3.3e-118 lssY 3.6.1.27 I phosphatase
PAKFEKLM_00802 1.3e-153 I alpha/beta hydrolase fold
PAKFEKLM_00803 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
PAKFEKLM_00804 4.6e-91 K Transcriptional regulator
PAKFEKLM_00805 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PAKFEKLM_00806 2.2e-263 lysP E amino acid
PAKFEKLM_00807 2.5e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PAKFEKLM_00808 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PAKFEKLM_00809 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PAKFEKLM_00817 6.9e-78 ctsR K Belongs to the CtsR family
PAKFEKLM_00818 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PAKFEKLM_00819 1.5e-109 K Bacterial regulatory proteins, tetR family
PAKFEKLM_00820 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAKFEKLM_00821 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAKFEKLM_00822 1.3e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PAKFEKLM_00823 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PAKFEKLM_00824 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PAKFEKLM_00825 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PAKFEKLM_00826 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PAKFEKLM_00827 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PAKFEKLM_00828 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
PAKFEKLM_00829 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PAKFEKLM_00830 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PAKFEKLM_00831 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PAKFEKLM_00832 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PAKFEKLM_00833 1.4e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PAKFEKLM_00834 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PAKFEKLM_00835 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
PAKFEKLM_00836 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PAKFEKLM_00837 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PAKFEKLM_00838 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PAKFEKLM_00839 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PAKFEKLM_00840 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PAKFEKLM_00841 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PAKFEKLM_00842 2.8e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PAKFEKLM_00843 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PAKFEKLM_00844 2.2e-24 rpmD J Ribosomal protein L30
PAKFEKLM_00845 6.3e-70 rplO J Binds to the 23S rRNA
PAKFEKLM_00846 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PAKFEKLM_00847 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PAKFEKLM_00848 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PAKFEKLM_00849 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PAKFEKLM_00850 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PAKFEKLM_00851 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAKFEKLM_00852 2.1e-61 rplQ J Ribosomal protein L17
PAKFEKLM_00853 5.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PAKFEKLM_00854 1.1e-93 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
PAKFEKLM_00855 1.4e-86 ynhH S NusG domain II
PAKFEKLM_00856 0.0 ndh 1.6.99.3 C NADH dehydrogenase
PAKFEKLM_00857 3.5e-142 cad S FMN_bind
PAKFEKLM_00858 5.8e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PAKFEKLM_00859 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAKFEKLM_00860 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAKFEKLM_00861 5e-145 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAKFEKLM_00862 8.7e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PAKFEKLM_00863 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PAKFEKLM_00864 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PAKFEKLM_00865 8.9e-164 degV S Uncharacterised protein, DegV family COG1307
PAKFEKLM_00866 1.5e-184 ywhK S Membrane
PAKFEKLM_00867 4.2e-203 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PAKFEKLM_00868 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PAKFEKLM_00869 4.8e-165 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PAKFEKLM_00870 8.9e-184 aroF 2.5.1.54 E DAHP synthetase I family
PAKFEKLM_00871 2.1e-194 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PAKFEKLM_00872 2.3e-240 P Sodium:sulfate symporter transmembrane region
PAKFEKLM_00873 4.1e-53 yitW S Iron-sulfur cluster assembly protein
PAKFEKLM_00874 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
PAKFEKLM_00875 4.4e-177 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
PAKFEKLM_00876 2.9e-198 K Helix-turn-helix domain
PAKFEKLM_00877 3.6e-154 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PAKFEKLM_00878 4.5e-132 mntB 3.6.3.35 P ABC transporter
PAKFEKLM_00879 4.8e-141 mtsB U ABC 3 transport family
PAKFEKLM_00880 1.2e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
PAKFEKLM_00881 3.1e-50
PAKFEKLM_00882 4.6e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PAKFEKLM_00883 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
PAKFEKLM_00884 2.9e-179 citR K sugar-binding domain protein
PAKFEKLM_00885 7.9e-208 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
PAKFEKLM_00886 3.3e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PAKFEKLM_00887 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
PAKFEKLM_00888 2.7e-163 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
PAKFEKLM_00889 7.8e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
PAKFEKLM_00890 1.1e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PAKFEKLM_00891 2.4e-264 frdC 1.3.5.4 C FAD binding domain
PAKFEKLM_00892 1.2e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PAKFEKLM_00893 1.2e-160 mleR K LysR family transcriptional regulator
PAKFEKLM_00894 1.8e-167 mleR K LysR family
PAKFEKLM_00895 4.7e-307 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PAKFEKLM_00896 1.4e-165 mleP S Sodium Bile acid symporter family
PAKFEKLM_00897 5.8e-253 yfnA E Amino Acid
PAKFEKLM_00898 3e-99 S ECF transporter, substrate-specific component
PAKFEKLM_00899 1.8e-23
PAKFEKLM_00900 6.6e-152 S Alpha beta
PAKFEKLM_00901 4e-29 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_00902 9.8e-38 tnp2PF3 L Transposase DDE domain
PAKFEKLM_00903 1.1e-129 S Alpha beta
PAKFEKLM_00904 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_00905 2e-76 L Transposase DDE domain
PAKFEKLM_00906 1.4e-14 S Alpha beta
PAKFEKLM_00907 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
PAKFEKLM_00908 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PAKFEKLM_00909 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PAKFEKLM_00910 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PAKFEKLM_00911 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
PAKFEKLM_00912 9.2e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PAKFEKLM_00913 8.5e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PAKFEKLM_00914 3.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
PAKFEKLM_00915 5.8e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
PAKFEKLM_00916 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PAKFEKLM_00917 1e-93 S UPF0316 protein
PAKFEKLM_00918 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PAKFEKLM_00919 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PAKFEKLM_00920 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PAKFEKLM_00921 1.8e-196 camS S sex pheromone
PAKFEKLM_00922 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PAKFEKLM_00923 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PAKFEKLM_00924 3.8e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PAKFEKLM_00925 1e-190 yegS 2.7.1.107 G Lipid kinase
PAKFEKLM_00926 3.4e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PAKFEKLM_00927 1.7e-99 yobS K Bacterial regulatory proteins, tetR family
PAKFEKLM_00928 0.0 yfgQ P E1-E2 ATPase
PAKFEKLM_00929 8.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_00930 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
PAKFEKLM_00931 1.5e-150 gntR K rpiR family
PAKFEKLM_00932 1.1e-144 lys M Glycosyl hydrolases family 25
PAKFEKLM_00933 1.1e-62 S Domain of unknown function (DUF4828)
PAKFEKLM_00934 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
PAKFEKLM_00935 2.4e-189 mocA S Oxidoreductase
PAKFEKLM_00936 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
PAKFEKLM_00938 2.3e-75 T Universal stress protein family
PAKFEKLM_00939 8.5e-243 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_00940 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
PAKFEKLM_00942 1.3e-73
PAKFEKLM_00943 5e-107
PAKFEKLM_00944 4.5e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PAKFEKLM_00945 3.8e-218 pbpX1 V Beta-lactamase
PAKFEKLM_00946 1.5e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PAKFEKLM_00947 3.9e-157 yihY S Belongs to the UPF0761 family
PAKFEKLM_00948 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PAKFEKLM_00949 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_00950 2e-76 L Transposase DDE domain
PAKFEKLM_00951 5.4e-14 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PAKFEKLM_00952 3.2e-52
PAKFEKLM_00953 7.3e-33 S Protein of unknown function (DUF2922)
PAKFEKLM_00954 7e-30
PAKFEKLM_00955 6.2e-25
PAKFEKLM_00956 2.8e-99 K DNA-templated transcription, initiation
PAKFEKLM_00957 1.8e-122
PAKFEKLM_00958 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
PAKFEKLM_00959 4.1e-106 ygaC J Belongs to the UPF0374 family
PAKFEKLM_00960 2.5e-133 cwlO M NlpC/P60 family
PAKFEKLM_00961 7.8e-48 K sequence-specific DNA binding
PAKFEKLM_00962 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
PAKFEKLM_00963 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PAKFEKLM_00964 9.3e-188 yueF S AI-2E family transporter
PAKFEKLM_00965 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
PAKFEKLM_00966 9.5e-213 gntP EG Gluconate
PAKFEKLM_00967 4.6e-293 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
PAKFEKLM_00968 7.3e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
PAKFEKLM_00969 2.8e-254 gor 1.8.1.7 C Glutathione reductase
PAKFEKLM_00970 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PAKFEKLM_00971 2.5e-272
PAKFEKLM_00972 6.5e-198 M MucBP domain
PAKFEKLM_00973 1.6e-160 lysR5 K LysR substrate binding domain
PAKFEKLM_00974 5.5e-126 yxaA S membrane transporter protein
PAKFEKLM_00975 3.2e-57 ywjH S Protein of unknown function (DUF1634)
PAKFEKLM_00976 1.3e-309 oppA E ABC transporter, substratebinding protein
PAKFEKLM_00977 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAKFEKLM_00978 9.5e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAKFEKLM_00979 9.2e-203 oppD P Belongs to the ABC transporter superfamily
PAKFEKLM_00980 1.8e-181 oppF P Belongs to the ABC transporter superfamily
PAKFEKLM_00981 5.2e-63 K Winged helix DNA-binding domain
PAKFEKLM_00982 1.6e-102 L Integrase
PAKFEKLM_00983 0.0 clpE O Belongs to the ClpA ClpB family
PAKFEKLM_00984 6.5e-30
PAKFEKLM_00985 2.7e-39 ptsH G phosphocarrier protein HPR
PAKFEKLM_00986 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PAKFEKLM_00987 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PAKFEKLM_00988 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
PAKFEKLM_00989 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PAKFEKLM_00990 1.9e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PAKFEKLM_00991 4.2e-225 patA 2.6.1.1 E Aminotransferase
PAKFEKLM_00992 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
PAKFEKLM_00993 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PAKFEKLM_00996 1.5e-42 S COG NOG38524 non supervised orthologous group
PAKFEKLM_01002 5.1e-08
PAKFEKLM_01008 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
PAKFEKLM_01009 1.8e-182 P secondary active sulfate transmembrane transporter activity
PAKFEKLM_01010 1.4e-95
PAKFEKLM_01011 2e-94 K Acetyltransferase (GNAT) domain
PAKFEKLM_01012 1.3e-156 T Calcineurin-like phosphoesterase superfamily domain
PAKFEKLM_01014 1.1e-229 mntH P H( )-stimulated, divalent metal cation uptake system
PAKFEKLM_01015 4.4e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PAKFEKLM_01016 1.7e-254 mmuP E amino acid
PAKFEKLM_01017 4.1e-167 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PAKFEKLM_01018 9.3e-294 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
PAKFEKLM_01019 3.1e-122
PAKFEKLM_01020 5.4e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PAKFEKLM_01021 4.2e-278 bmr3 EGP Major facilitator Superfamily
PAKFEKLM_01022 9.1e-139 N Cell shape-determining protein MreB
PAKFEKLM_01023 0.0 S Pfam Methyltransferase
PAKFEKLM_01024 1e-158 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
PAKFEKLM_01025 3e-65 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
PAKFEKLM_01026 7.5e-299 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
PAKFEKLM_01027 4.2e-29
PAKFEKLM_01028 1e-93 ytqB 2.1.1.176 J Putative rRNA methylase
PAKFEKLM_01029 8.8e-124 3.6.1.27 I Acid phosphatase homologues
PAKFEKLM_01030 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PAKFEKLM_01031 3e-301 ytgP S Polysaccharide biosynthesis protein
PAKFEKLM_01032 6.7e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PAKFEKLM_01033 6.4e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PAKFEKLM_01034 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
PAKFEKLM_01035 4.1e-84 uspA T Belongs to the universal stress protein A family
PAKFEKLM_01036 6.1e-202 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
PAKFEKLM_01037 1.8e-173 ugpA U Binding-protein-dependent transport system inner membrane component
PAKFEKLM_01038 1.1e-150 ugpE G ABC transporter permease
PAKFEKLM_01039 1.2e-260 ugpB G Bacterial extracellular solute-binding protein
PAKFEKLM_01040 3.8e-125 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PAKFEKLM_01041 5e-119 dck 2.7.1.74 F deoxynucleoside kinase
PAKFEKLM_01042 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PAKFEKLM_01043 5.1e-179 XK27_06930 V domain protein
PAKFEKLM_01045 2.5e-127 V Transport permease protein
PAKFEKLM_01046 2.3e-156 V ABC transporter
PAKFEKLM_01047 3.6e-166 K LytTr DNA-binding domain
PAKFEKLM_01049 6.3e-156 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PAKFEKLM_01050 1.6e-64 K helix_turn_helix, mercury resistance
PAKFEKLM_01051 2.3e-116 GM NAD(P)H-binding
PAKFEKLM_01052 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PAKFEKLM_01053 2.2e-148 S Sucrose-6F-phosphate phosphohydrolase
PAKFEKLM_01054 1.7e-108
PAKFEKLM_01055 2.2e-224 pltK 2.7.13.3 T GHKL domain
PAKFEKLM_01056 1.6e-137 pltR K LytTr DNA-binding domain
PAKFEKLM_01057 4.5e-55
PAKFEKLM_01058 2.5e-59
PAKFEKLM_01059 8.7e-114 S CAAX protease self-immunity
PAKFEKLM_01060 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
PAKFEKLM_01061 1e-90
PAKFEKLM_01062 2.5e-46
PAKFEKLM_01063 0.0 uvrA2 L ABC transporter
PAKFEKLM_01066 3e-56
PAKFEKLM_01067 3.5e-10
PAKFEKLM_01068 2.1e-180
PAKFEKLM_01069 1.9e-89 gtcA S Teichoic acid glycosylation protein
PAKFEKLM_01070 3.6e-58 S Protein of unknown function (DUF1516)
PAKFEKLM_01071 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PAKFEKLM_01072 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PAKFEKLM_01073 2e-305 S Protein conserved in bacteria
PAKFEKLM_01074 1.8e-228 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
PAKFEKLM_01075 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
PAKFEKLM_01076 8.5e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
PAKFEKLM_01077 2.1e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
PAKFEKLM_01078 0.0 yfbS P Sodium:sulfate symporter transmembrane region
PAKFEKLM_01079 2.1e-244 dinF V MatE
PAKFEKLM_01080 1.9e-31
PAKFEKLM_01083 2.7e-79 elaA S Acetyltransferase (GNAT) domain
PAKFEKLM_01084 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PAKFEKLM_01085 5.5e-83
PAKFEKLM_01086 0.0 yhcA V MacB-like periplasmic core domain
PAKFEKLM_01087 9.8e-38 tnp2PF3 L Transposase DDE domain
PAKFEKLM_01088 4e-29 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_01089 7.6e-107
PAKFEKLM_01090 0.0 K PRD domain
PAKFEKLM_01091 5.9e-61 S Domain of unknown function (DUF3284)
PAKFEKLM_01092 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PAKFEKLM_01093 1.6e-07 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PAKFEKLM_01094 2e-25 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PAKFEKLM_01095 5.4e-175 L Transposase and inactivated derivatives, IS30 family
PAKFEKLM_01096 3.6e-219 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_01097 1.8e-289 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PAKFEKLM_01098 2.7e-211 EGP Major facilitator Superfamily
PAKFEKLM_01099 2e-114 M ErfK YbiS YcfS YnhG
PAKFEKLM_01100 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAKFEKLM_01101 7.1e-283 ydfD K Alanine-glyoxylate amino-transferase
PAKFEKLM_01102 4e-102 argO S LysE type translocator
PAKFEKLM_01103 3e-212 arcT 2.6.1.1 E Aminotransferase
PAKFEKLM_01104 4.4e-77 argR K Regulates arginine biosynthesis genes
PAKFEKLM_01105 2.9e-12
PAKFEKLM_01106 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PAKFEKLM_01107 1e-54 yheA S Belongs to the UPF0342 family
PAKFEKLM_01108 1.3e-232 yhaO L Ser Thr phosphatase family protein
PAKFEKLM_01109 0.0 L AAA domain
PAKFEKLM_01110 8.4e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
PAKFEKLM_01111 6.2e-213
PAKFEKLM_01112 1.3e-179 3.4.21.102 M Peptidase family S41
PAKFEKLM_01113 3.4e-177 K LysR substrate binding domain
PAKFEKLM_01114 4.7e-111 1.3.5.4 S NADPH-dependent FMN reductase
PAKFEKLM_01115 0.0 1.3.5.4 C FAD binding domain
PAKFEKLM_01116 1.7e-99
PAKFEKLM_01117 3.1e-31 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PAKFEKLM_01118 9.1e-220 L Transposase
PAKFEKLM_01119 9e-38 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PAKFEKLM_01120 5.2e-184 ykoT GT2 M Glycosyl transferase family 2
PAKFEKLM_01121 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PAKFEKLM_01122 1.7e-19 S NUDIX domain
PAKFEKLM_01123 0.0 S membrane
PAKFEKLM_01124 6.8e-129 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PAKFEKLM_01125 8.8e-71 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
PAKFEKLM_01126 1.4e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PAKFEKLM_01127 2.1e-82 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PAKFEKLM_01128 4.6e-105 GBS0088 S Nucleotidyltransferase
PAKFEKLM_01129 1.4e-106
PAKFEKLM_01130 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PAKFEKLM_01131 3.3e-112 K Bacterial regulatory proteins, tetR family
PAKFEKLM_01132 2.1e-241 npr 1.11.1.1 C NADH oxidase
PAKFEKLM_01133 0.0
PAKFEKLM_01134 1e-57
PAKFEKLM_01135 1.4e-192 S Fn3-like domain
PAKFEKLM_01136 5.1e-82 S WxL domain surface cell wall-binding
PAKFEKLM_01137 2e-13 S WxL domain surface cell wall-binding
PAKFEKLM_01138 3.5e-78 S WxL domain surface cell wall-binding
PAKFEKLM_01139 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PAKFEKLM_01140 2e-42
PAKFEKLM_01141 9.9e-82 hit FG histidine triad
PAKFEKLM_01142 1.6e-134 ecsA V ABC transporter, ATP-binding protein
PAKFEKLM_01143 1.4e-223 ecsB U ABC transporter
PAKFEKLM_01144 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
PAKFEKLM_01145 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PAKFEKLM_01146 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
PAKFEKLM_01147 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PAKFEKLM_01148 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
PAKFEKLM_01149 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PAKFEKLM_01150 7.9e-21 S Virus attachment protein p12 family
PAKFEKLM_01151 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PAKFEKLM_01152 2.2e-34 feoA P FeoA domain
PAKFEKLM_01153 4.2e-144 sufC O FeS assembly ATPase SufC
PAKFEKLM_01154 2.6e-244 sufD O FeS assembly protein SufD
PAKFEKLM_01155 3.1e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PAKFEKLM_01156 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
PAKFEKLM_01157 1.4e-272 sufB O assembly protein SufB
PAKFEKLM_01158 1e-177 fecB P Periplasmic binding protein
PAKFEKLM_01159 1.3e-137 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
PAKFEKLM_01160 1.6e-165 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAKFEKLM_01161 4.5e-70 moaE 2.8.1.12 H MoaE protein
PAKFEKLM_01162 5.4e-34 moaD 2.8.1.12 H ThiS family
PAKFEKLM_01163 4.5e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PAKFEKLM_01164 2.5e-217 narK P Transporter, major facilitator family protein
PAKFEKLM_01165 8.8e-59 yitW S Iron-sulfur cluster assembly protein
PAKFEKLM_01166 2.1e-157 hipB K Helix-turn-helix
PAKFEKLM_01167 9e-50 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
PAKFEKLM_01168 1.1e-85 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
PAKFEKLM_01169 1.5e-183
PAKFEKLM_01170 1.5e-49
PAKFEKLM_01171 6.1e-117 nreC K PFAM regulatory protein LuxR
PAKFEKLM_01172 3.5e-191 comP 2.7.13.3 F Sensor histidine kinase
PAKFEKLM_01173 1.3e-23 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
PAKFEKLM_01174 7.8e-39
PAKFEKLM_01175 2.5e-99 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PAKFEKLM_01176 7.2e-86 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PAKFEKLM_01177 1.8e-89 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
PAKFEKLM_01178 1.5e-230 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
PAKFEKLM_01179 1.6e-82 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PAKFEKLM_01180 3.2e-192 moeB 2.7.7.73, 2.7.7.80 H ThiF family
PAKFEKLM_01181 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAKFEKLM_01182 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
PAKFEKLM_01183 7.3e-98 narJ C Nitrate reductase delta subunit
PAKFEKLM_01184 2.7e-123 narI 1.7.5.1 C Nitrate reductase
PAKFEKLM_01185 1.5e-175
PAKFEKLM_01186 3.1e-74
PAKFEKLM_01187 7.3e-98 S Protein of unknown function (DUF2975)
PAKFEKLM_01188 1.7e-28 yozG K Transcriptional regulator
PAKFEKLM_01189 4.5e-121 ybhL S Belongs to the BI1 family
PAKFEKLM_01190 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PAKFEKLM_01191 1.7e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PAKFEKLM_01192 2.7e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PAKFEKLM_01193 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PAKFEKLM_01194 1.1e-248 dnaB L replication initiation and membrane attachment
PAKFEKLM_01195 3.3e-172 dnaI L Primosomal protein DnaI
PAKFEKLM_01196 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PAKFEKLM_01197 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PAKFEKLM_01198 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PAKFEKLM_01199 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PAKFEKLM_01200 9.9e-57
PAKFEKLM_01201 1.4e-237 yrvN L AAA C-terminal domain
PAKFEKLM_01202 2.2e-193 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PAKFEKLM_01203 5.6e-44 hxlR K Transcriptional regulator, HxlR family
PAKFEKLM_01204 1.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
PAKFEKLM_01205 1.8e-248 pgaC GT2 M Glycosyl transferase
PAKFEKLM_01206 1.3e-79
PAKFEKLM_01207 1.4e-98 yqeG S HAD phosphatase, family IIIA
PAKFEKLM_01208 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
PAKFEKLM_01209 1.1e-50 yhbY J RNA-binding protein
PAKFEKLM_01210 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PAKFEKLM_01211 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PAKFEKLM_01212 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PAKFEKLM_01213 4.4e-140 yqeM Q Methyltransferase
PAKFEKLM_01214 5.4e-217 ylbM S Belongs to the UPF0348 family
PAKFEKLM_01215 1e-96 yceD S Uncharacterized ACR, COG1399
PAKFEKLM_01216 2.2e-89 S Peptidase propeptide and YPEB domain
PAKFEKLM_01217 1.1e-170 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAKFEKLM_01218 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PAKFEKLM_01219 4.2e-245 rarA L recombination factor protein RarA
PAKFEKLM_01220 4.3e-121 K response regulator
PAKFEKLM_01221 5.2e-306 arlS 2.7.13.3 T Histidine kinase
PAKFEKLM_01222 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PAKFEKLM_01223 0.0 sbcC L Putative exonuclease SbcCD, C subunit
PAKFEKLM_01224 4.5e-227 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PAKFEKLM_01225 8.4e-94 S SdpI/YhfL protein family
PAKFEKLM_01226 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PAKFEKLM_01227 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PAKFEKLM_01228 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PAKFEKLM_01229 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PAKFEKLM_01230 7.4e-64 yodB K Transcriptional regulator, HxlR family
PAKFEKLM_01231 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PAKFEKLM_01232 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PAKFEKLM_01233 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PAKFEKLM_01234 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
PAKFEKLM_01235 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PAKFEKLM_01236 2.3e-96 liaI S membrane
PAKFEKLM_01237 4e-75 XK27_02470 K LytTr DNA-binding domain
PAKFEKLM_01238 1.5e-54 yneR S Belongs to the HesB IscA family
PAKFEKLM_01239 0.0 S membrane
PAKFEKLM_01240 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PAKFEKLM_01241 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PAKFEKLM_01242 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PAKFEKLM_01243 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
PAKFEKLM_01244 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
PAKFEKLM_01245 5.7e-180 glk 2.7.1.2 G Glucokinase
PAKFEKLM_01246 1.9e-110 pepE 3.4.13.21 E Belongs to the peptidase S51 family
PAKFEKLM_01247 4.4e-68 yqhL P Rhodanese-like protein
PAKFEKLM_01248 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
PAKFEKLM_01249 3.8e-139 glpQ 3.1.4.46 C phosphodiesterase
PAKFEKLM_01250 4.1e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PAKFEKLM_01251 4.6e-64 glnR K Transcriptional regulator
PAKFEKLM_01252 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
PAKFEKLM_01253 2.5e-161
PAKFEKLM_01254 4e-181
PAKFEKLM_01255 6.9e-98 dut S Protein conserved in bacteria
PAKFEKLM_01256 5.3e-56
PAKFEKLM_01257 1.7e-30
PAKFEKLM_01260 5.4e-19
PAKFEKLM_01261 1.8e-89 K Transcriptional regulator
PAKFEKLM_01262 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PAKFEKLM_01263 3.2e-53 ysxB J Cysteine protease Prp
PAKFEKLM_01264 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PAKFEKLM_01265 5.9e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PAKFEKLM_01266 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PAKFEKLM_01267 3.5e-74 yqhY S Asp23 family, cell envelope-related function
PAKFEKLM_01268 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PAKFEKLM_01269 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PAKFEKLM_01270 3e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PAKFEKLM_01271 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PAKFEKLM_01272 2.4e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PAKFEKLM_01273 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PAKFEKLM_01274 7.4e-77 argR K Regulates arginine biosynthesis genes
PAKFEKLM_01275 5.7e-308 recN L May be involved in recombinational repair of damaged DNA
PAKFEKLM_01276 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
PAKFEKLM_01277 1.2e-104 opuCB E ABC transporter permease
PAKFEKLM_01278 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PAKFEKLM_01279 6.4e-106 opuCD P Binding-protein-dependent transport system inner membrane component
PAKFEKLM_01280 4.5e-55
PAKFEKLM_01281 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PAKFEKLM_01282 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PAKFEKLM_01283 2e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PAKFEKLM_01284 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PAKFEKLM_01285 1.9e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PAKFEKLM_01286 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PAKFEKLM_01287 1.7e-134 stp 3.1.3.16 T phosphatase
PAKFEKLM_01288 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PAKFEKLM_01289 9.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PAKFEKLM_01290 6.1e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PAKFEKLM_01291 5.8e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
PAKFEKLM_01292 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PAKFEKLM_01293 1.8e-57 asp S Asp23 family, cell envelope-related function
PAKFEKLM_01294 0.0 yloV S DAK2 domain fusion protein YloV
PAKFEKLM_01295 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PAKFEKLM_01296 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PAKFEKLM_01297 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAKFEKLM_01298 2.8e-128 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PAKFEKLM_01299 0.0 smc D Required for chromosome condensation and partitioning
PAKFEKLM_01300 6.6e-170 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PAKFEKLM_01301 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PAKFEKLM_01302 2.9e-220 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PAKFEKLM_01303 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PAKFEKLM_01304 1e-38 ylqC S Belongs to the UPF0109 family
PAKFEKLM_01305 2.4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PAKFEKLM_01306 1e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PAKFEKLM_01307 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PAKFEKLM_01308 1.4e-50
PAKFEKLM_01309 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
PAKFEKLM_01310 4.5e-31
PAKFEKLM_01311 5.3e-136 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
PAKFEKLM_01312 8.1e-272 XK27_00765
PAKFEKLM_01314 3.7e-196 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
PAKFEKLM_01315 4e-29 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_01316 9.8e-38 tnp2PF3 L Transposase DDE domain
PAKFEKLM_01317 7.3e-29 K Bacterial regulatory proteins, tetR family
PAKFEKLM_01318 4.5e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PAKFEKLM_01319 3.7e-301 ybeC E amino acid
PAKFEKLM_01320 1.5e-194 L Transposase and inactivated derivatives, IS30 family
PAKFEKLM_01321 2.7e-103 tnpR L Resolvase, N terminal domain
PAKFEKLM_01323 4.5e-219 L Transposase
PAKFEKLM_01324 2e-172 ybfG M peptidoglycan-binding domain-containing protein
PAKFEKLM_01325 4.5e-174 L Integrase core domain
PAKFEKLM_01327 1.5e-178 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PAKFEKLM_01328 2.5e-32 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
PAKFEKLM_01329 8.7e-145 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PAKFEKLM_01330 9.9e-89 L Psort location Cytoplasmic, score
PAKFEKLM_01331 4e-29 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_01332 9.8e-38 tnp2PF3 L Transposase DDE domain
PAKFEKLM_01333 5.8e-21 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PAKFEKLM_01334 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PAKFEKLM_01335 2e-97 entB 3.5.1.19 Q Isochorismatase family
PAKFEKLM_01336 1.3e-176 1.6.5.5 C Zinc-binding dehydrogenase
PAKFEKLM_01337 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
PAKFEKLM_01338 4.1e-122 E glutamate:sodium symporter activity
PAKFEKLM_01339 8.3e-85 E glutamate:sodium symporter activity
PAKFEKLM_01340 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
PAKFEKLM_01341 2.7e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PAKFEKLM_01342 8.5e-60 S Protein of unknown function (DUF1648)
PAKFEKLM_01343 6.6e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PAKFEKLM_01344 1.5e-178 yneE K Transcriptional regulator
PAKFEKLM_01345 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PAKFEKLM_01346 1.1e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAKFEKLM_01347 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAKFEKLM_01348 4.4e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PAKFEKLM_01349 1.2e-126 IQ reductase
PAKFEKLM_01350 1.6e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PAKFEKLM_01351 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PAKFEKLM_01352 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
PAKFEKLM_01353 5.2e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PAKFEKLM_01354 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PAKFEKLM_01355 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PAKFEKLM_01356 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PAKFEKLM_01357 1.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
PAKFEKLM_01358 2.2e-123 S Protein of unknown function (DUF554)
PAKFEKLM_01359 3.3e-158 K LysR substrate binding domain
PAKFEKLM_01360 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
PAKFEKLM_01361 6.5e-193 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PAKFEKLM_01362 4e-93 K transcriptional regulator
PAKFEKLM_01363 8e-302 norB EGP Major Facilitator
PAKFEKLM_01364 1.2e-139 f42a O Band 7 protein
PAKFEKLM_01365 2.7e-85 S Protein of unknown function with HXXEE motif
PAKFEKLM_01366 8.4e-14 K Bacterial regulatory proteins, tetR family
PAKFEKLM_01367 1.1e-53
PAKFEKLM_01368 2.4e-207 L Transposase
PAKFEKLM_01369 6.2e-28
PAKFEKLM_01370 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PAKFEKLM_01371 3.8e-113 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
PAKFEKLM_01372 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
PAKFEKLM_01373 7.9e-41
PAKFEKLM_01374 1.6e-66 tspO T TspO/MBR family
PAKFEKLM_01375 6.3e-76 uspA T Belongs to the universal stress protein A family
PAKFEKLM_01376 8e-66 S Protein of unknown function (DUF805)
PAKFEKLM_01377 7e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
PAKFEKLM_01378 3.5e-36
PAKFEKLM_01379 3.1e-14
PAKFEKLM_01380 6.5e-41 S transglycosylase associated protein
PAKFEKLM_01381 4.8e-29 S CsbD-like
PAKFEKLM_01382 9.4e-40
PAKFEKLM_01383 8.6e-281 pipD E Dipeptidase
PAKFEKLM_01384 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PAKFEKLM_01385 1.3e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PAKFEKLM_01386 1e-170 2.5.1.74 H UbiA prenyltransferase family
PAKFEKLM_01387 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
PAKFEKLM_01388 3.9e-50
PAKFEKLM_01389 2.4e-43
PAKFEKLM_01390 1.4e-256 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAKFEKLM_01391 1.4e-265 yfnA E Amino Acid
PAKFEKLM_01392 1.2e-149 yitU 3.1.3.104 S hydrolase
PAKFEKLM_01393 1.8e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PAKFEKLM_01394 2.9e-82 S Domain of unknown function (DUF4767)
PAKFEKLM_01395 1.3e-249 malT G Major Facilitator
PAKFEKLM_01396 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PAKFEKLM_01397 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PAKFEKLM_01398 1.1e-195 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PAKFEKLM_01399 7.6e-205 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PAKFEKLM_01400 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PAKFEKLM_01401 9e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PAKFEKLM_01402 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PAKFEKLM_01403 2.1e-72 ypmB S protein conserved in bacteria
PAKFEKLM_01404 4.3e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PAKFEKLM_01405 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PAKFEKLM_01406 1.3e-128 dnaD L Replication initiation and membrane attachment
PAKFEKLM_01408 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PAKFEKLM_01409 2e-99 metI P ABC transporter permease
PAKFEKLM_01410 2.7e-157 metQ_4 P Belongs to the nlpA lipoprotein family
PAKFEKLM_01411 7.6e-83 uspA T Universal stress protein family
PAKFEKLM_01412 2.7e-302 ftpA P Binding-protein-dependent transport system inner membrane component
PAKFEKLM_01413 1.7e-182 ftpB P Bacterial extracellular solute-binding protein
PAKFEKLM_01414 1.8e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
PAKFEKLM_01415 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PAKFEKLM_01416 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PAKFEKLM_01417 8.3e-110 ypsA S Belongs to the UPF0398 family
PAKFEKLM_01418 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PAKFEKLM_01420 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PAKFEKLM_01421 3.4e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
PAKFEKLM_01422 3e-243 P Major Facilitator Superfamily
PAKFEKLM_01423 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
PAKFEKLM_01424 4.4e-73 S SnoaL-like domain
PAKFEKLM_01425 6.2e-241 M Glycosyltransferase, group 2 family protein
PAKFEKLM_01426 2.5e-26 mccF V LD-carboxypeptidase
PAKFEKLM_01427 1.9e-169 mccF V LD-carboxypeptidase
PAKFEKLM_01428 1.4e-78 K Acetyltransferase (GNAT) domain
PAKFEKLM_01429 6.9e-240 M hydrolase, family 25
PAKFEKLM_01430 6.2e-182 mccF 3.4.17.13 V LD-carboxypeptidase
PAKFEKLM_01431 6e-124
PAKFEKLM_01432 6.6e-122 3.6.3.35 P ATPases associated with a variety of cellular activities
PAKFEKLM_01433 2.1e-194
PAKFEKLM_01434 1e-145 S hydrolase activity, acting on ester bonds
PAKFEKLM_01435 3.2e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
PAKFEKLM_01436 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
PAKFEKLM_01437 3.3e-62 esbA S Family of unknown function (DUF5322)
PAKFEKLM_01438 4.1e-295 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PAKFEKLM_01439 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PAKFEKLM_01440 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PAKFEKLM_01441 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PAKFEKLM_01442 2.8e-207 carA 6.3.5.5 F Belongs to the CarA family
PAKFEKLM_01443 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PAKFEKLM_01444 4e-288 S Bacterial membrane protein, YfhO
PAKFEKLM_01445 6.4e-113 pgm5 G Phosphoglycerate mutase family
PAKFEKLM_01446 3.5e-32 frataxin S Domain of unknown function (DU1801)
PAKFEKLM_01448 1.1e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
PAKFEKLM_01449 1.7e-46 S LuxR family transcriptional regulator
PAKFEKLM_01450 8.6e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
PAKFEKLM_01452 1.2e-91 3.6.1.55 F NUDIX domain
PAKFEKLM_01453 9.2e-164 V ABC transporter, ATP-binding protein
PAKFEKLM_01454 3.2e-37 S ABC-2 family transporter protein
PAKFEKLM_01455 3.4e-77 S ABC-2 family transporter protein
PAKFEKLM_01456 0.0 FbpA K Fibronectin-binding protein
PAKFEKLM_01457 1.9e-66 K Transcriptional regulator
PAKFEKLM_01458 7e-161 degV S EDD domain protein, DegV family
PAKFEKLM_01459 3.2e-77 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
PAKFEKLM_01460 1.3e-131 S Protein of unknown function (DUF975)
PAKFEKLM_01461 4.3e-10
PAKFEKLM_01462 1.4e-49
PAKFEKLM_01463 3.3e-149 2.7.7.12 C Domain of unknown function (DUF4931)
PAKFEKLM_01464 8.9e-207 pmrB EGP Major facilitator Superfamily
PAKFEKLM_01465 4.6e-12
PAKFEKLM_01466 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
PAKFEKLM_01467 4.6e-129 yejC S Protein of unknown function (DUF1003)
PAKFEKLM_01468 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
PAKFEKLM_01469 2.1e-244 cycA E Amino acid permease
PAKFEKLM_01470 1.8e-116
PAKFEKLM_01471 4.1e-59
PAKFEKLM_01472 1.4e-279 lldP C L-lactate permease
PAKFEKLM_01473 2.6e-226
PAKFEKLM_01474 3.7e-128 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
PAKFEKLM_01475 1.2e-191 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
PAKFEKLM_01476 8.6e-196 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PAKFEKLM_01477 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PAKFEKLM_01478 8.5e-93 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PAKFEKLM_01479 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
PAKFEKLM_01480 1e-238 gshR1 1.8.1.7 C Glutathione reductase
PAKFEKLM_01481 2.1e-51
PAKFEKLM_01482 1e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PAKFEKLM_01483 4.4e-233 M Glycosyl transferase family group 2
PAKFEKLM_01484 2.3e-276 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PAKFEKLM_01485 1e-156 xerD L Phage integrase, N-terminal SAM-like domain
PAKFEKLM_01486 4.2e-32 S YozE SAM-like fold
PAKFEKLM_01487 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PAKFEKLM_01488 8.9e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PAKFEKLM_01489 1.4e-167 ppaC 3.6.1.1 C inorganic pyrophosphatase
PAKFEKLM_01490 1.2e-177 K Transcriptional regulator
PAKFEKLM_01491 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PAKFEKLM_01492 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PAKFEKLM_01493 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PAKFEKLM_01494 2.2e-170 lacX 5.1.3.3 G Aldose 1-epimerase
PAKFEKLM_01495 8.6e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PAKFEKLM_01496 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PAKFEKLM_01497 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
PAKFEKLM_01498 2.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PAKFEKLM_01499 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PAKFEKLM_01500 3.3e-158 dprA LU DNA protecting protein DprA
PAKFEKLM_01501 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PAKFEKLM_01502 4.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PAKFEKLM_01504 1.4e-228 XK27_05470 E Methionine synthase
PAKFEKLM_01505 8.9e-170 cpsY K Transcriptional regulator, LysR family
PAKFEKLM_01506 2.3e-173 L restriction endonuclease
PAKFEKLM_01507 7.2e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PAKFEKLM_01508 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
PAKFEKLM_01509 3.3e-251 emrY EGP Major facilitator Superfamily
PAKFEKLM_01510 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
PAKFEKLM_01511 3.4e-35 yozE S Belongs to the UPF0346 family
PAKFEKLM_01512 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PAKFEKLM_01513 2.8e-147 ypmR E GDSL-like Lipase/Acylhydrolase
PAKFEKLM_01514 2e-147 DegV S EDD domain protein, DegV family
PAKFEKLM_01515 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PAKFEKLM_01516 3.9e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PAKFEKLM_01517 0.0 yfmR S ABC transporter, ATP-binding protein
PAKFEKLM_01518 9.6e-85
PAKFEKLM_01519 3.2e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PAKFEKLM_01520 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PAKFEKLM_01521 3.7e-148 3.1.3.102, 3.1.3.104 S hydrolase
PAKFEKLM_01522 3.3e-215 S Tetratricopeptide repeat protein
PAKFEKLM_01523 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PAKFEKLM_01524 5.1e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PAKFEKLM_01525 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
PAKFEKLM_01526 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PAKFEKLM_01527 2e-19 M Lysin motif
PAKFEKLM_01528 5.8e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
PAKFEKLM_01529 3.5e-191 ypbB 5.1.3.1 S Helix-turn-helix domain
PAKFEKLM_01530 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PAKFEKLM_01531 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PAKFEKLM_01532 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PAKFEKLM_01533 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PAKFEKLM_01534 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAKFEKLM_01535 1.1e-164 xerD D recombinase XerD
PAKFEKLM_01536 2.9e-170 cvfB S S1 domain
PAKFEKLM_01537 1.5e-74 yeaL S Protein of unknown function (DUF441)
PAKFEKLM_01538 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PAKFEKLM_01539 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PAKFEKLM_01540 0.0 dnaE 2.7.7.7 L DNA polymerase
PAKFEKLM_01541 5.6e-29 S Protein of unknown function (DUF2929)
PAKFEKLM_01543 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PAKFEKLM_01544 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PAKFEKLM_01545 7.2e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PAKFEKLM_01546 1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
PAKFEKLM_01547 6.9e-223 M O-Antigen ligase
PAKFEKLM_01548 1.6e-119 drrB U ABC-2 type transporter
PAKFEKLM_01549 3.2e-167 drrA V ABC transporter
PAKFEKLM_01550 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
PAKFEKLM_01551 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PAKFEKLM_01552 5.1e-60 P Rhodanese Homology Domain
PAKFEKLM_01553 8.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
PAKFEKLM_01554 2.3e-207
PAKFEKLM_01555 1.5e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
PAKFEKLM_01556 2.6e-180 C Zinc-binding dehydrogenase
PAKFEKLM_01557 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
PAKFEKLM_01558 2.6e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PAKFEKLM_01559 2.2e-241 EGP Major facilitator Superfamily
PAKFEKLM_01560 4.3e-77 K Transcriptional regulator
PAKFEKLM_01561 9.2e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PAKFEKLM_01562 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PAKFEKLM_01563 3e-136 K DeoR C terminal sensor domain
PAKFEKLM_01564 1.2e-106 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
PAKFEKLM_01565 9.1e-71 yneH 1.20.4.1 P ArsC family
PAKFEKLM_01566 4.1e-68 S Protein of unknown function (DUF1722)
PAKFEKLM_01567 2e-112 GM epimerase
PAKFEKLM_01568 0.0 CP_1020 S Zinc finger, swim domain protein
PAKFEKLM_01569 9.2e-82 K Bacterial regulatory proteins, tetR family
PAKFEKLM_01570 4.7e-214 S membrane
PAKFEKLM_01571 1.2e-14 K Bacterial regulatory proteins, tetR family
PAKFEKLM_01573 3.4e-72 S Alpha/beta hydrolase of unknown function (DUF915)
PAKFEKLM_01574 1.4e-19 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_01576 1.2e-112 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
PAKFEKLM_01577 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
PAKFEKLM_01578 6.5e-128 K Helix-turn-helix domain, rpiR family
PAKFEKLM_01579 8.5e-159 S Alpha beta hydrolase
PAKFEKLM_01580 9.9e-112 GM NmrA-like family
PAKFEKLM_01581 4.9e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
PAKFEKLM_01582 1.9e-161 K Transcriptional regulator
PAKFEKLM_01583 1.9e-172 C nadph quinone reductase
PAKFEKLM_01584 6.3e-14 S Alpha beta hydrolase
PAKFEKLM_01585 2.1e-271 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PAKFEKLM_01586 4e-102 desR K helix_turn_helix, Lux Regulon
PAKFEKLM_01587 2.8e-207 desK 2.7.13.3 T Histidine kinase
PAKFEKLM_01588 3.1e-136 yvfS V ABC-2 type transporter
PAKFEKLM_01589 5.2e-159 yvfR V ABC transporter
PAKFEKLM_01591 6e-82 K Acetyltransferase (GNAT) domain
PAKFEKLM_01592 6.2e-73 K MarR family
PAKFEKLM_01593 1e-114 S Psort location CytoplasmicMembrane, score
PAKFEKLM_01594 2.6e-12 yjdF S Protein of unknown function (DUF2992)
PAKFEKLM_01595 3.3e-161 V ABC transporter, ATP-binding protein
PAKFEKLM_01596 9.8e-127 S ABC-2 family transporter protein
PAKFEKLM_01597 1.4e-198
PAKFEKLM_01598 3.5e-202
PAKFEKLM_01599 6.3e-165 ytrB V ABC transporter, ATP-binding protein
PAKFEKLM_01600 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
PAKFEKLM_01601 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PAKFEKLM_01602 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PAKFEKLM_01603 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PAKFEKLM_01604 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PAKFEKLM_01605 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
PAKFEKLM_01606 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PAKFEKLM_01607 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PAKFEKLM_01608 6.6e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PAKFEKLM_01609 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
PAKFEKLM_01610 2.6e-71 yqeY S YqeY-like protein
PAKFEKLM_01611 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PAKFEKLM_01612 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PAKFEKLM_01613 5.5e-127 C Enoyl-(Acyl carrier protein) reductase
PAKFEKLM_01614 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PAKFEKLM_01615 6.6e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PAKFEKLM_01616 5.1e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PAKFEKLM_01617 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PAKFEKLM_01618 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PAKFEKLM_01619 8.3e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
PAKFEKLM_01620 4.3e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PAKFEKLM_01621 1.2e-162 yniA G Fructosamine kinase
PAKFEKLM_01622 6.5e-116 3.1.3.18 J HAD-hyrolase-like
PAKFEKLM_01623 3.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PAKFEKLM_01624 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PAKFEKLM_01625 9.6e-58
PAKFEKLM_01626 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PAKFEKLM_01627 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
PAKFEKLM_01628 4e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PAKFEKLM_01629 1.4e-49
PAKFEKLM_01630 1.4e-49
PAKFEKLM_01633 2.3e-127 3.6.4.12 L Belongs to the 'phage' integrase family
PAKFEKLM_01634 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PAKFEKLM_01635 6.8e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PAKFEKLM_01636 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAKFEKLM_01637 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
PAKFEKLM_01638 2.6e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAKFEKLM_01639 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
PAKFEKLM_01640 7e-196 pbpX2 V Beta-lactamase
PAKFEKLM_01641 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PAKFEKLM_01642 0.0 dnaK O Heat shock 70 kDa protein
PAKFEKLM_01643 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PAKFEKLM_01644 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PAKFEKLM_01645 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
PAKFEKLM_01646 2.7e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PAKFEKLM_01647 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PAKFEKLM_01648 2e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PAKFEKLM_01649 6.5e-196 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PAKFEKLM_01650 1e-232 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PAKFEKLM_01651 8.5e-93
PAKFEKLM_01652 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PAKFEKLM_01653 7.9e-97 ydiN 5.4.99.5 G Major Facilitator
PAKFEKLM_01654 1.1e-150 ydiN 5.4.99.5 G Major Facilitator
PAKFEKLM_01655 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PAKFEKLM_01656 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PAKFEKLM_01657 1.1e-47 ylxQ J ribosomal protein
PAKFEKLM_01658 9.5e-49 ylxR K Protein of unknown function (DUF448)
PAKFEKLM_01659 3.3e-217 nusA K Participates in both transcription termination and antitermination
PAKFEKLM_01660 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
PAKFEKLM_01661 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PAKFEKLM_01662 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PAKFEKLM_01663 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PAKFEKLM_01664 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
PAKFEKLM_01665 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PAKFEKLM_01666 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PAKFEKLM_01667 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PAKFEKLM_01668 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PAKFEKLM_01669 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
PAKFEKLM_01670 4.7e-134 S Haloacid dehalogenase-like hydrolase
PAKFEKLM_01671 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAKFEKLM_01672 7e-39 yazA L GIY-YIG catalytic domain protein
PAKFEKLM_01673 2.1e-132 yabB 2.1.1.223 L Methyltransferase small domain
PAKFEKLM_01674 6.4e-119 plsC 2.3.1.51 I Acyltransferase
PAKFEKLM_01675 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
PAKFEKLM_01676 2.9e-36 ynzC S UPF0291 protein
PAKFEKLM_01677 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PAKFEKLM_01678 3.7e-87
PAKFEKLM_01679 1.8e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PAKFEKLM_01680 4.6e-75
PAKFEKLM_01681 3e-66
PAKFEKLM_01682 1.5e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
PAKFEKLM_01683 9.2e-101 L Helix-turn-helix domain
PAKFEKLM_01684 9.6e-208 lytR5 K Cell envelope-related transcriptional attenuator domain
PAKFEKLM_01685 5.4e-77 L Transposase DDE domain
PAKFEKLM_01686 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_01687 3e-142 P ATPases associated with a variety of cellular activities
PAKFEKLM_01688 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
PAKFEKLM_01689 2.2e-229 rodA D Cell cycle protein
PAKFEKLM_01691 1.6e-31
PAKFEKLM_01692 2.3e-119 Q Methyltransferase
PAKFEKLM_01693 8.5e-57 ybjQ S Belongs to the UPF0145 family
PAKFEKLM_01694 4.6e-122 EGP Major facilitator Superfamily
PAKFEKLM_01695 1.5e-98 K Helix-turn-helix domain
PAKFEKLM_01696 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PAKFEKLM_01697 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PAKFEKLM_01698 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
PAKFEKLM_01699 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PAKFEKLM_01700 8.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PAKFEKLM_01701 3.2e-46
PAKFEKLM_01702 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PAKFEKLM_01703 1.5e-135 fruR K DeoR C terminal sensor domain
PAKFEKLM_01704 2.3e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PAKFEKLM_01705 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
PAKFEKLM_01706 1e-251 cpdA S Calcineurin-like phosphoesterase
PAKFEKLM_01707 1.1e-173 cps4J S Polysaccharide biosynthesis protein
PAKFEKLM_01708 6.7e-72 cps4J S Polysaccharide biosynthesis protein
PAKFEKLM_01709 2.3e-176 cps4I M Glycosyltransferase like family 2
PAKFEKLM_01710 1.3e-232
PAKFEKLM_01711 2.8e-188 cps4G M Glycosyltransferase Family 4
PAKFEKLM_01712 1.1e-107 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
PAKFEKLM_01713 3.3e-68 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
PAKFEKLM_01714 1.8e-127 tuaA M Bacterial sugar transferase
PAKFEKLM_01715 2.1e-179 cps4D 5.1.3.2 M RmlD substrate binding domain
PAKFEKLM_01716 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
PAKFEKLM_01717 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PAKFEKLM_01718 6.2e-90 epsB M biosynthesis protein
PAKFEKLM_01719 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PAKFEKLM_01720 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PAKFEKLM_01721 9.2e-270 glnPH2 P ABC transporter permease
PAKFEKLM_01722 4.3e-22
PAKFEKLM_01723 9.9e-73 S Iron-sulphur cluster biosynthesis
PAKFEKLM_01724 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PAKFEKLM_01725 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PAKFEKLM_01726 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PAKFEKLM_01727 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PAKFEKLM_01728 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PAKFEKLM_01729 3.1e-159 S Tetratricopeptide repeat
PAKFEKLM_01730 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PAKFEKLM_01731 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PAKFEKLM_01732 6.3e-192 mdtG EGP Major Facilitator Superfamily
PAKFEKLM_01733 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PAKFEKLM_01734 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
PAKFEKLM_01735 9.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
PAKFEKLM_01736 4.1e-71 comEC S Competence protein ComEC
PAKFEKLM_01737 0.0 comEC S Competence protein ComEC
PAKFEKLM_01738 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
PAKFEKLM_01739 5.6e-127 comEA L Competence protein ComEA
PAKFEKLM_01740 1.6e-196 ylbL T Belongs to the peptidase S16 family
PAKFEKLM_01741 2.1e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PAKFEKLM_01742 8.2e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PAKFEKLM_01743 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PAKFEKLM_01744 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PAKFEKLM_01745 1.6e-205 ftsW D Belongs to the SEDS family
PAKFEKLM_01746 3.4e-286
PAKFEKLM_01747 5.1e-259 ica2 GT2 M Glycosyl transferase family group 2
PAKFEKLM_01748 1.2e-103
PAKFEKLM_01749 4.8e-55
PAKFEKLM_01750 1e-63
PAKFEKLM_01751 7.1e-63
PAKFEKLM_01752 0.0 typA T GTP-binding protein TypA
PAKFEKLM_01753 1.8e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PAKFEKLM_01754 1.6e-45 yktA S Belongs to the UPF0223 family
PAKFEKLM_01755 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
PAKFEKLM_01756 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
PAKFEKLM_01757 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PAKFEKLM_01758 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PAKFEKLM_01759 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PAKFEKLM_01760 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PAKFEKLM_01761 1.6e-85
PAKFEKLM_01762 3.1e-33 ykzG S Belongs to the UPF0356 family
PAKFEKLM_01763 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PAKFEKLM_01764 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PAKFEKLM_01765 1.7e-28
PAKFEKLM_01766 2.6e-107 mltD CBM50 M NlpC P60 family protein
PAKFEKLM_01767 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PAKFEKLM_01768 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PAKFEKLM_01769 1.6e-120 S Repeat protein
PAKFEKLM_01770 3.5e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PAKFEKLM_01771 5.5e-267 N domain, Protein
PAKFEKLM_01772 7e-192 S Bacterial protein of unknown function (DUF916)
PAKFEKLM_01773 8.7e-120 N WxL domain surface cell wall-binding
PAKFEKLM_01774 2.6e-115 ktrA P domain protein
PAKFEKLM_01775 1.1e-240 ktrB P Potassium uptake protein
PAKFEKLM_01776 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PAKFEKLM_01777 4.9e-57 XK27_04120 S Putative amino acid metabolism
PAKFEKLM_01778 1.4e-215 iscS 2.8.1.7 E Aminotransferase class V
PAKFEKLM_01779 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PAKFEKLM_01780 4.6e-28
PAKFEKLM_01781 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PAKFEKLM_01782 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PAKFEKLM_01783 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PAKFEKLM_01784 3.5e-86 divIVA D DivIVA domain protein
PAKFEKLM_01785 3.4e-146 ylmH S S4 domain protein
PAKFEKLM_01786 1.2e-36 yggT S YGGT family
PAKFEKLM_01787 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PAKFEKLM_01788 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PAKFEKLM_01789 2.7e-244 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PAKFEKLM_01790 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PAKFEKLM_01791 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PAKFEKLM_01792 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PAKFEKLM_01793 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PAKFEKLM_01794 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PAKFEKLM_01795 7.5e-54 ftsL D Cell division protein FtsL
PAKFEKLM_01796 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PAKFEKLM_01797 1.9e-77 mraZ K Belongs to the MraZ family
PAKFEKLM_01798 7.1e-62 S Protein of unknown function (DUF3397)
PAKFEKLM_01799 1.6e-174 corA P CorA-like Mg2+ transporter protein
PAKFEKLM_01800 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PAKFEKLM_01801 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PAKFEKLM_01802 2.4e-113 ywnB S NAD(P)H-binding
PAKFEKLM_01803 1.1e-208 brnQ U Component of the transport system for branched-chain amino acids
PAKFEKLM_01805 1.2e-160 rrmA 2.1.1.187 H Methyltransferase
PAKFEKLM_01806 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PAKFEKLM_01807 4.3e-206 XK27_05220 S AI-2E family transporter
PAKFEKLM_01808 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PAKFEKLM_01809 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PAKFEKLM_01810 2.1e-114 cutC P Participates in the control of copper homeostasis
PAKFEKLM_01811 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PAKFEKLM_01812 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PAKFEKLM_01813 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
PAKFEKLM_01814 3.6e-114 yjbH Q Thioredoxin
PAKFEKLM_01815 0.0 pepF E oligoendopeptidase F
PAKFEKLM_01816 1.5e-205 coiA 3.6.4.12 S Competence protein
PAKFEKLM_01817 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PAKFEKLM_01818 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PAKFEKLM_01819 2.7e-137 yhfI S Metallo-beta-lactamase superfamily
PAKFEKLM_01820 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PAKFEKLM_01830 5.5e-08
PAKFEKLM_01842 1.5e-42 S COG NOG38524 non supervised orthologous group
PAKFEKLM_01843 3.5e-64
PAKFEKLM_01844 1.6e-75 yugI 5.3.1.9 J general stress protein
PAKFEKLM_01845 6.1e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PAKFEKLM_01846 2.5e-118 dedA S SNARE-like domain protein
PAKFEKLM_01847 1.8e-116 S Protein of unknown function (DUF1461)
PAKFEKLM_01848 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PAKFEKLM_01849 1.5e-80 yutD S Protein of unknown function (DUF1027)
PAKFEKLM_01850 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PAKFEKLM_01851 1.3e-116 S Calcineurin-like phosphoesterase
PAKFEKLM_01852 8.1e-252 cycA E Amino acid permease
PAKFEKLM_01853 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PAKFEKLM_01854 2.3e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
PAKFEKLM_01856 1.9e-61 S Prokaryotic N-terminal methylation motif
PAKFEKLM_01857 8.6e-20
PAKFEKLM_01858 3.2e-83 gspG NU general secretion pathway protein
PAKFEKLM_01859 7.1e-43 comGC U competence protein ComGC
PAKFEKLM_01860 1.9e-189 comGB NU type II secretion system
PAKFEKLM_01861 2.1e-174 comGA NU Type II IV secretion system protein
PAKFEKLM_01862 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAKFEKLM_01863 8.3e-131 yebC K Transcriptional regulatory protein
PAKFEKLM_01864 1.6e-49 S DsrE/DsrF-like family
PAKFEKLM_01865 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
PAKFEKLM_01866 2.7e-180 ccpA K catabolite control protein A
PAKFEKLM_01867 6.3e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PAKFEKLM_01868 1.1e-80 K helix_turn_helix, mercury resistance
PAKFEKLM_01869 2.8e-56
PAKFEKLM_01870 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PAKFEKLM_01871 1.3e-157 ykuT M mechanosensitive ion channel
PAKFEKLM_01872 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PAKFEKLM_01873 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PAKFEKLM_01874 6.5e-87 ykuL S (CBS) domain
PAKFEKLM_01875 9.5e-97 S Phosphoesterase
PAKFEKLM_01876 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PAKFEKLM_01877 3.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PAKFEKLM_01878 7.6e-126 yslB S Protein of unknown function (DUF2507)
PAKFEKLM_01879 3.3e-52 trxA O Belongs to the thioredoxin family
PAKFEKLM_01880 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PAKFEKLM_01881 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PAKFEKLM_01882 1.6e-48 yrzB S Belongs to the UPF0473 family
PAKFEKLM_01883 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PAKFEKLM_01884 2.4e-43 yrzL S Belongs to the UPF0297 family
PAKFEKLM_01885 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PAKFEKLM_01886 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PAKFEKLM_01887 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PAKFEKLM_01888 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PAKFEKLM_01889 2.8e-29 yajC U Preprotein translocase
PAKFEKLM_01890 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PAKFEKLM_01891 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PAKFEKLM_01892 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PAKFEKLM_01893 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PAKFEKLM_01894 7.4e-89
PAKFEKLM_01895 0.0 S Bacterial membrane protein YfhO
PAKFEKLM_01896 3.1e-71
PAKFEKLM_01897 0.0 L Transposase
PAKFEKLM_01898 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PAKFEKLM_01899 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PAKFEKLM_01900 2.7e-154 ymdB S YmdB-like protein
PAKFEKLM_01901 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
PAKFEKLM_01902 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PAKFEKLM_01903 2.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
PAKFEKLM_01904 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PAKFEKLM_01905 4.8e-109 ymfM S Helix-turn-helix domain
PAKFEKLM_01906 1.1e-250 ymfH S Peptidase M16
PAKFEKLM_01907 1.2e-230 ymfF S Peptidase M16 inactive domain protein
PAKFEKLM_01908 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
PAKFEKLM_01909 1.5e-155 aatB ET ABC transporter substrate-binding protein
PAKFEKLM_01910 7.4e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PAKFEKLM_01911 4.6e-109 glnP P ABC transporter permease
PAKFEKLM_01912 1.2e-146 minD D Belongs to the ParA family
PAKFEKLM_01913 5.3e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PAKFEKLM_01914 1.2e-88 mreD M rod shape-determining protein MreD
PAKFEKLM_01915 7.6e-144 mreC M Involved in formation and maintenance of cell shape
PAKFEKLM_01916 2.8e-161 mreB D cell shape determining protein MreB
PAKFEKLM_01917 1.3e-116 radC L DNA repair protein
PAKFEKLM_01918 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PAKFEKLM_01919 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PAKFEKLM_01920 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PAKFEKLM_01921 4.4e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PAKFEKLM_01922 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PAKFEKLM_01923 8.3e-218 iscS2 2.8.1.7 E Aminotransferase class V
PAKFEKLM_01924 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PAKFEKLM_01925 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
PAKFEKLM_01926 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PAKFEKLM_01927 5.2e-113 yktB S Belongs to the UPF0637 family
PAKFEKLM_01928 3.3e-80 yueI S Protein of unknown function (DUF1694)
PAKFEKLM_01929 2e-109 S Protein of unknown function (DUF1648)
PAKFEKLM_01930 8.6e-44 czrA K Helix-turn-helix domain
PAKFEKLM_01931 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PAKFEKLM_01932 6.8e-237 rarA L recombination factor protein RarA
PAKFEKLM_01933 1.5e-38
PAKFEKLM_01934 6.2e-82 usp6 T universal stress protein
PAKFEKLM_01935 3.1e-201 bla2 3.5.2.6 V Beta-lactamase enzyme family
PAKFEKLM_01936 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
PAKFEKLM_01937 1.3e-295 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
PAKFEKLM_01938 1.6e-213 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PAKFEKLM_01939 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PAKFEKLM_01940 5.1e-176 S Protein of unknown function (DUF2785)
PAKFEKLM_01941 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
PAKFEKLM_01942 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
PAKFEKLM_01943 1.4e-111 metI U ABC transporter permease
PAKFEKLM_01944 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PAKFEKLM_01945 3.6e-48 gcsH2 E glycine cleavage
PAKFEKLM_01946 3.5e-219 rodA D Belongs to the SEDS family
PAKFEKLM_01947 3.3e-33 S Protein of unknown function (DUF2969)
PAKFEKLM_01948 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PAKFEKLM_01949 2.7e-180 mbl D Cell shape determining protein MreB Mrl
PAKFEKLM_01950 6.2e-102 J Acetyltransferase (GNAT) domain
PAKFEKLM_01951 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PAKFEKLM_01952 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PAKFEKLM_01953 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PAKFEKLM_01954 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PAKFEKLM_01955 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PAKFEKLM_01956 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PAKFEKLM_01957 7.9e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PAKFEKLM_01958 4.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PAKFEKLM_01959 8.4e-128 atpB C it plays a direct role in the translocation of protons across the membrane
PAKFEKLM_01960 3.3e-231 pyrP F Permease
PAKFEKLM_01961 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PAKFEKLM_01962 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PAKFEKLM_01963 7.7e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PAKFEKLM_01964 1.1e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PAKFEKLM_01965 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PAKFEKLM_01966 9.3e-109 tdk 2.7.1.21 F thymidine kinase
PAKFEKLM_01967 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
PAKFEKLM_01968 5.9e-137 cobQ S glutamine amidotransferase
PAKFEKLM_01969 2.8e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
PAKFEKLM_01970 2e-191 ampC V Beta-lactamase
PAKFEKLM_01971 1.4e-29
PAKFEKLM_01972 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PAKFEKLM_01973 1.9e-58
PAKFEKLM_01974 4.8e-126
PAKFEKLM_01975 0.0 yfiC V ABC transporter
PAKFEKLM_01976 0.0 ycfI V ABC transporter, ATP-binding protein
PAKFEKLM_01977 1.6e-67 S Protein of unknown function (DUF1093)
PAKFEKLM_01978 5.4e-77 L Transposase DDE domain
PAKFEKLM_01979 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_01980 3.8e-135 yxkH G Polysaccharide deacetylase
PAKFEKLM_01983 9.9e-29
PAKFEKLM_01986 2.4e-57
PAKFEKLM_01987 6.2e-39 S Phage gp6-like head-tail connector protein
PAKFEKLM_01990 4.3e-278 S Caudovirus prohead serine protease
PAKFEKLM_01991 3.2e-203 S Phage portal protein
PAKFEKLM_01993 0.0 terL S overlaps another CDS with the same product name
PAKFEKLM_01994 2.5e-80 terS L overlaps another CDS with the same product name
PAKFEKLM_01995 9.8e-70 L Phage-associated protein
PAKFEKLM_01996 3.1e-51 S head-tail joining protein
PAKFEKLM_01997 2.6e-23
PAKFEKLM_01998 4.5e-85
PAKFEKLM_01999 3.2e-264 S Virulence-associated protein E
PAKFEKLM_02000 3.2e-136 L DNA replication protein
PAKFEKLM_02001 7.6e-30
PAKFEKLM_02003 3.9e-15 K Cro/C1-type HTH DNA-binding domain
PAKFEKLM_02004 4.3e-222 sip L Belongs to the 'phage' integrase family
PAKFEKLM_02005 1.7e-37
PAKFEKLM_02006 7.1e-43
PAKFEKLM_02007 7.3e-83 K MarR family
PAKFEKLM_02008 2.1e-306 bztC D nuclear chromosome segregation
PAKFEKLM_02009 9.7e-295 M MucBP domain
PAKFEKLM_02011 2.7e-16
PAKFEKLM_02012 7.2e-17
PAKFEKLM_02013 5.2e-15
PAKFEKLM_02014 1.1e-18
PAKFEKLM_02015 1.6e-16
PAKFEKLM_02016 1.6e-16
PAKFEKLM_02017 1.9e-18
PAKFEKLM_02018 1.6e-16
PAKFEKLM_02019 2.4e-311 msbA2 3.6.3.44 P ABC transporter transmembrane region
PAKFEKLM_02020 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
PAKFEKLM_02021 0.0 macB3 V ABC transporter, ATP-binding protein
PAKFEKLM_02022 6.8e-24
PAKFEKLM_02023 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
PAKFEKLM_02024 1.7e-154 glcU U sugar transport
PAKFEKLM_02025 3.2e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
PAKFEKLM_02026 2.9e-287 yclK 2.7.13.3 T Histidine kinase
PAKFEKLM_02027 1.6e-134 K response regulator
PAKFEKLM_02028 2.5e-242 XK27_08635 S UPF0210 protein
PAKFEKLM_02029 8.9e-38 gcvR T Belongs to the UPF0237 family
PAKFEKLM_02030 1.5e-169 EG EamA-like transporter family
PAKFEKLM_02033 3.5e-174 L Transposase and inactivated derivatives, IS30 family
PAKFEKLM_02034 6.2e-09
PAKFEKLM_02035 5.2e-17
PAKFEKLM_02036 1.7e-126 S Virulence-associated protein E
PAKFEKLM_02039 2.3e-20
PAKFEKLM_02040 4.6e-62 S Phage regulatory protein Rha (Phage_pRha)
PAKFEKLM_02041 2.1e-08 K Cro/C1-type HTH DNA-binding domain
PAKFEKLM_02042 1.2e-107 sip L Phage integrase, N-terminal SAM-like domain
PAKFEKLM_02043 7.7e-92 S ECF-type riboflavin transporter, S component
PAKFEKLM_02044 8.6e-48
PAKFEKLM_02045 9.8e-214 yceI EGP Major facilitator Superfamily
PAKFEKLM_02046 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
PAKFEKLM_02047 3.8e-23
PAKFEKLM_02049 5.9e-160 S Alpha/beta hydrolase of unknown function (DUF915)
PAKFEKLM_02050 1.4e-172 ykfC 3.4.14.13 M NlpC/P60 family
PAKFEKLM_02051 8.6e-81 K AsnC family
PAKFEKLM_02052 2e-35
PAKFEKLM_02053 5.1e-34
PAKFEKLM_02054 1e-215 2.7.7.65 T diguanylate cyclase
PAKFEKLM_02055 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_02056 2e-76 L Transposase DDE domain
PAKFEKLM_02057 1.5e-294 S ABC transporter, ATP-binding protein
PAKFEKLM_02058 2e-106 3.2.2.20 K acetyltransferase
PAKFEKLM_02059 2.4e-80 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAKFEKLM_02060 1e-38
PAKFEKLM_02061 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
PAKFEKLM_02062 1.4e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAKFEKLM_02063 5e-162 degV S Uncharacterised protein, DegV family COG1307
PAKFEKLM_02064 2.8e-230 hom1 1.1.1.3 E Homoserine dehydrogenase
PAKFEKLM_02065 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PAKFEKLM_02066 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PAKFEKLM_02067 1.4e-176 XK27_08835 S ABC transporter
PAKFEKLM_02068 2.5e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PAKFEKLM_02069 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
PAKFEKLM_02070 5.7e-258 npr 1.11.1.1 C NADH oxidase
PAKFEKLM_02071 4.2e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
PAKFEKLM_02072 4.8e-137 terC P membrane
PAKFEKLM_02073 5.3e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PAKFEKLM_02074 6.6e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PAKFEKLM_02075 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PAKFEKLM_02076 3.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PAKFEKLM_02077 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PAKFEKLM_02078 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PAKFEKLM_02079 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PAKFEKLM_02080 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PAKFEKLM_02081 1.2e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PAKFEKLM_02082 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PAKFEKLM_02083 8e-213 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PAKFEKLM_02084 3.8e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
PAKFEKLM_02085 4.6e-216 ysaA V RDD family
PAKFEKLM_02086 7.6e-166 corA P CorA-like Mg2+ transporter protein
PAKFEKLM_02087 2.1e-55 S Domain of unknown function (DU1801)
PAKFEKLM_02088 5.9e-91 rmeB K transcriptional regulator, MerR family
PAKFEKLM_02089 6.5e-148 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
PAKFEKLM_02090 8.6e-98 J glyoxalase III activity
PAKFEKLM_02091 8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PAKFEKLM_02092 4.8e-187 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PAKFEKLM_02093 3.7e-34
PAKFEKLM_02094 9.2e-112 S Protein of unknown function (DUF1211)
PAKFEKLM_02095 0.0 ydgH S MMPL family
PAKFEKLM_02096 1.6e-288 M domain protein
PAKFEKLM_02097 1.1e-74 yjcF S Acetyltransferase (GNAT) domain
PAKFEKLM_02098 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PAKFEKLM_02099 0.0 glpQ 3.1.4.46 C phosphodiesterase
PAKFEKLM_02100 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PAKFEKLM_02101 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
PAKFEKLM_02102 1.4e-181 3.6.4.13 S domain, Protein
PAKFEKLM_02103 3.6e-168 S Polyphosphate kinase 2 (PPK2)
PAKFEKLM_02104 2.5e-98 drgA C Nitroreductase family
PAKFEKLM_02105 2.7e-177 iunH2 3.2.2.1 F nucleoside hydrolase
PAKFEKLM_02106 1.3e-149 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PAKFEKLM_02107 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
PAKFEKLM_02108 2.3e-157 ccpB 5.1.1.1 K lacI family
PAKFEKLM_02109 2.4e-116 K Helix-turn-helix domain, rpiR family
PAKFEKLM_02110 1.7e-71 S Oxidoreductase family, NAD-binding Rossmann fold
PAKFEKLM_02111 6.8e-170 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PAKFEKLM_02112 4.4e-40 S Oxidoreductase family, NAD-binding Rossmann fold
PAKFEKLM_02113 9.4e-38 S Oxidoreductase family, NAD-binding Rossmann fold
PAKFEKLM_02114 3.2e-39 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
PAKFEKLM_02115 4.4e-143 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
PAKFEKLM_02116 0.0 yjcE P Sodium proton antiporter
PAKFEKLM_02117 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PAKFEKLM_02118 3.7e-107 pncA Q Isochorismatase family
PAKFEKLM_02119 2.7e-132
PAKFEKLM_02120 5.1e-125 skfE V ABC transporter
PAKFEKLM_02121 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
PAKFEKLM_02122 1.2e-45 S Enterocin A Immunity
PAKFEKLM_02123 1.7e-173 D Alpha beta
PAKFEKLM_02124 0.0 pepF2 E Oligopeptidase F
PAKFEKLM_02125 1.3e-72 K Transcriptional regulator
PAKFEKLM_02126 3e-164
PAKFEKLM_02128 1.2e-58
PAKFEKLM_02129 2.2e-47
PAKFEKLM_02130 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PAKFEKLM_02131 4.2e-68
PAKFEKLM_02132 2.4e-144 yjfP S Dienelactone hydrolase family
PAKFEKLM_02133 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
PAKFEKLM_02134 1.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PAKFEKLM_02135 5.2e-47
PAKFEKLM_02136 6.3e-45
PAKFEKLM_02137 1.5e-81 yybC S Protein of unknown function (DUF2798)
PAKFEKLM_02138 1.7e-73
PAKFEKLM_02139 4e-60
PAKFEKLM_02140 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
PAKFEKLM_02141 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
PAKFEKLM_02142 3e-72 G PTS system fructose IIA component
PAKFEKLM_02143 3.2e-147 G PTS system mannose/fructose/sorbose family IID component
PAKFEKLM_02144 4.7e-143 agaC G PTS system sorbose-specific iic component
PAKFEKLM_02145 1.2e-85 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
PAKFEKLM_02146 2.2e-128 K UTRA domain
PAKFEKLM_02147 4.7e-79 uspA T universal stress protein
PAKFEKLM_02148 4.3e-153 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PAKFEKLM_02149 7.5e-20
PAKFEKLM_02150 9.3e-44 S zinc-ribbon domain
PAKFEKLM_02151 2.1e-69 S response to antibiotic
PAKFEKLM_02152 1.7e-48 K Cro/C1-type HTH DNA-binding domain
PAKFEKLM_02153 3.3e-21 S Protein of unknown function (DUF2929)
PAKFEKLM_02154 1e-223 lsgC M Glycosyl transferases group 1
PAKFEKLM_02155 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PAKFEKLM_02156 4.3e-163 S Putative esterase
PAKFEKLM_02157 2.4e-130 gntR2 K Transcriptional regulator
PAKFEKLM_02158 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PAKFEKLM_02159 9.8e-138
PAKFEKLM_02160 1.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PAKFEKLM_02161 5.5e-138 rrp8 K LytTr DNA-binding domain
PAKFEKLM_02162 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
PAKFEKLM_02163 7.7e-61
PAKFEKLM_02164 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
PAKFEKLM_02165 2.2e-57
PAKFEKLM_02166 1.2e-239 yhdP S Transporter associated domain
PAKFEKLM_02167 4.9e-87 nrdI F Belongs to the NrdI family
PAKFEKLM_02168 2.6e-270 yjcE P Sodium proton antiporter
PAKFEKLM_02169 2.8e-213 yttB EGP Major facilitator Superfamily
PAKFEKLM_02170 1.2e-61 K helix_turn_helix, mercury resistance
PAKFEKLM_02171 1.5e-172 C Zinc-binding dehydrogenase
PAKFEKLM_02172 8.5e-57 S SdpI/YhfL protein family
PAKFEKLM_02173 1.8e-294 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PAKFEKLM_02174 5.5e-261 gabR K Bacterial regulatory proteins, gntR family
PAKFEKLM_02175 5e-218 patA 2.6.1.1 E Aminotransferase
PAKFEKLM_02176 8e-143 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PAKFEKLM_02177 3e-18
PAKFEKLM_02178 1.7e-126 S membrane transporter protein
PAKFEKLM_02179 1.9e-161 mleR K LysR family
PAKFEKLM_02180 5.6e-115 ylbE GM NAD(P)H-binding
PAKFEKLM_02181 8.2e-96 wecD K Acetyltransferase (GNAT) family
PAKFEKLM_02182 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PAKFEKLM_02183 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PAKFEKLM_02184 1.3e-171 ydcZ S Putative inner membrane exporter, YdcZ
PAKFEKLM_02185 4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PAKFEKLM_02186 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PAKFEKLM_02187 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PAKFEKLM_02188 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PAKFEKLM_02189 1.2e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PAKFEKLM_02190 1.5e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PAKFEKLM_02191 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PAKFEKLM_02192 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PAKFEKLM_02193 1e-298 pucR QT Purine catabolism regulatory protein-like family
PAKFEKLM_02194 2.7e-236 pbuX F xanthine permease
PAKFEKLM_02195 2.4e-221 pbuG S Permease family
PAKFEKLM_02196 5.6e-161 GM NmrA-like family
PAKFEKLM_02197 6.5e-156 T EAL domain
PAKFEKLM_02198 4.4e-94
PAKFEKLM_02199 2.7e-252 pgaC GT2 M Glycosyl transferase
PAKFEKLM_02200 3.3e-126 2.1.1.14 E Methionine synthase
PAKFEKLM_02201 3.5e-214 purD 6.3.4.13 F Belongs to the GARS family
PAKFEKLM_02202 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PAKFEKLM_02203 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PAKFEKLM_02204 7.2e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PAKFEKLM_02205 3.3e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PAKFEKLM_02206 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAKFEKLM_02207 1.7e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAKFEKLM_02208 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAKFEKLM_02209 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PAKFEKLM_02210 1.5e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PAKFEKLM_02211 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PAKFEKLM_02212 1.5e-223 XK27_09615 1.3.5.4 S reductase
PAKFEKLM_02213 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
PAKFEKLM_02214 1.4e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
PAKFEKLM_02215 5.3e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
PAKFEKLM_02216 9.2e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
PAKFEKLM_02217 7.5e-149 S Alpha/beta hydrolase of unknown function (DUF915)
PAKFEKLM_02218 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
PAKFEKLM_02219 5.1e-139 cysA V ABC transporter, ATP-binding protein
PAKFEKLM_02220 0.0 V FtsX-like permease family
PAKFEKLM_02221 8e-42
PAKFEKLM_02222 1.8e-60 gntR1 K Transcriptional regulator, GntR family
PAKFEKLM_02223 6.9e-164 V ABC transporter, ATP-binding protein
PAKFEKLM_02224 5.8e-149
PAKFEKLM_02225 6.7e-81 uspA T universal stress protein
PAKFEKLM_02226 1.2e-35
PAKFEKLM_02227 4.2e-71 gtcA S Teichoic acid glycosylation protein
PAKFEKLM_02228 1.1e-88
PAKFEKLM_02229 9.4e-50
PAKFEKLM_02231 2.8e-232 malY 4.4.1.8 E Aminotransferase, class I
PAKFEKLM_02232 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
PAKFEKLM_02233 2.7e-117
PAKFEKLM_02234 1.5e-52
PAKFEKLM_02236 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PAKFEKLM_02237 3.6e-282 thrC 4.2.3.1 E Threonine synthase
PAKFEKLM_02238 1.3e-145 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
PAKFEKLM_02239 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
PAKFEKLM_02240 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PAKFEKLM_02241 1.7e-102 3.6.1.13 L Belongs to the Nudix hydrolase family
PAKFEKLM_02242 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
PAKFEKLM_02243 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
PAKFEKLM_02244 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
PAKFEKLM_02245 2.5e-211 S Bacterial protein of unknown function (DUF871)
PAKFEKLM_02246 2.3e-231 S Sterol carrier protein domain
PAKFEKLM_02247 1e-205 EGP Major facilitator Superfamily
PAKFEKLM_02248 6.1e-88 niaR S 3H domain
PAKFEKLM_02249 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PAKFEKLM_02250 1.3e-117 K Transcriptional regulator
PAKFEKLM_02251 1.3e-155 V ABC transporter
PAKFEKLM_02252 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
PAKFEKLM_02253 1.1e-245 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
PAKFEKLM_02254 5.2e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PAKFEKLM_02255 9.5e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PAKFEKLM_02256 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
PAKFEKLM_02257 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PAKFEKLM_02258 1.8e-130 gntR K UTRA
PAKFEKLM_02259 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
PAKFEKLM_02260 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PAKFEKLM_02261 1.8e-81
PAKFEKLM_02262 9.8e-152 S hydrolase
PAKFEKLM_02263 2.7e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAKFEKLM_02264 8.3e-152 EG EamA-like transporter family
PAKFEKLM_02265 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PAKFEKLM_02266 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PAKFEKLM_02267 8.2e-235
PAKFEKLM_02268 4.2e-77 fld C Flavodoxin
PAKFEKLM_02269 0.0 M Bacterial Ig-like domain (group 3)
PAKFEKLM_02270 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
PAKFEKLM_02271 2.7e-32
PAKFEKLM_02272 3e-128 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
PAKFEKLM_02273 2.2e-268 ycaM E amino acid
PAKFEKLM_02274 1.8e-78 K Winged helix DNA-binding domain
PAKFEKLM_02275 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
PAKFEKLM_02276 2.8e-162 akr5f 1.1.1.346 S reductase
PAKFEKLM_02277 8.6e-162 K Transcriptional regulator
PAKFEKLM_02279 1.5e-42 S COG NOG38524 non supervised orthologous group
PAKFEKLM_02280 1.8e-84 hmpT S Pfam:DUF3816
PAKFEKLM_02281 3.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PAKFEKLM_02282 3.9e-111
PAKFEKLM_02283 2.4e-149 M Glycosyl hydrolases family 25
PAKFEKLM_02284 2.2e-142 yvpB S Peptidase_C39 like family
PAKFEKLM_02285 1.1e-92 yueI S Protein of unknown function (DUF1694)
PAKFEKLM_02286 6e-115 S Protein of unknown function (DUF554)
PAKFEKLM_02287 3.9e-145 KT helix_turn_helix, mercury resistance
PAKFEKLM_02288 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PAKFEKLM_02289 6.6e-95 S Protein of unknown function (DUF1440)
PAKFEKLM_02290 9.9e-173 hrtB V ABC transporter permease
PAKFEKLM_02291 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PAKFEKLM_02292 1.4e-90 2.7.7.65 T phosphorelay sensor kinase activity
PAKFEKLM_02293 5.5e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PAKFEKLM_02294 2.4e-98 1.5.1.3 H RibD C-terminal domain
PAKFEKLM_02295 5.3e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PAKFEKLM_02296 3.9e-79 S Membrane
PAKFEKLM_02297 8e-155 mleP3 S Membrane transport protein
PAKFEKLM_02298 7.2e-256 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
PAKFEKLM_02299 7.6e-190 ynfM EGP Major facilitator Superfamily
PAKFEKLM_02300 9e-124 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PAKFEKLM_02301 1.6e-269 lmrB EGP Major facilitator Superfamily
PAKFEKLM_02302 5.8e-75 S Domain of unknown function (DUF4811)
PAKFEKLM_02303 2.7e-97 rimL J Acetyltransferase (GNAT) domain
PAKFEKLM_02304 1.2e-172 S Conserved hypothetical protein 698
PAKFEKLM_02305 3.1e-150 rlrG K Transcriptional regulator
PAKFEKLM_02306 7.6e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
PAKFEKLM_02307 2e-267 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
PAKFEKLM_02309 2.3e-52 lytE M LysM domain
PAKFEKLM_02310 5.2e-92 ogt 2.1.1.63 L Methyltransferase
PAKFEKLM_02311 4e-167 natA S ABC transporter, ATP-binding protein
PAKFEKLM_02312 2.3e-210 natB CP ABC-2 family transporter protein
PAKFEKLM_02313 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PAKFEKLM_02314 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
PAKFEKLM_02315 1.3e-74 yphH S Cupin domain
PAKFEKLM_02316 9.8e-79 K transcriptional regulator, MerR family
PAKFEKLM_02317 1.7e-235 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PAKFEKLM_02318 0.0 ylbB V ABC transporter permease
PAKFEKLM_02319 7.5e-121 macB V ABC transporter, ATP-binding protein
PAKFEKLM_02321 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PAKFEKLM_02322 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PAKFEKLM_02323 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PAKFEKLM_02325 3.8e-84
PAKFEKLM_02326 2.8e-85 yvbK 3.1.3.25 K GNAT family
PAKFEKLM_02327 3.2e-37
PAKFEKLM_02328 8.2e-48
PAKFEKLM_02329 1.4e-110 pgm8 G Histidine phosphatase superfamily (branch 1)
PAKFEKLM_02330 3.8e-63 S Domain of unknown function (DUF4440)
PAKFEKLM_02331 6.9e-156 K LysR substrate binding domain
PAKFEKLM_02332 3.2e-104 GM NAD(P)H-binding
PAKFEKLM_02333 1.5e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PAKFEKLM_02334 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
PAKFEKLM_02335 1.3e-34
PAKFEKLM_02336 6.1e-76 T Belongs to the universal stress protein A family
PAKFEKLM_02337 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
PAKFEKLM_02338 1.7e-125 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PAKFEKLM_02339 6.3e-62
PAKFEKLM_02340 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PAKFEKLM_02341 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
PAKFEKLM_02342 7.4e-102 M Protein of unknown function (DUF3737)
PAKFEKLM_02343 1.2e-194 C Aldo/keto reductase family
PAKFEKLM_02345 0.0 mdlB V ABC transporter
PAKFEKLM_02346 0.0 mdlA V ABC transporter
PAKFEKLM_02347 1.3e-246 EGP Major facilitator Superfamily
PAKFEKLM_02350 3.6e-09
PAKFEKLM_02351 4.7e-198 yhgE V domain protein
PAKFEKLM_02352 5.1e-96 K Transcriptional regulator (TetR family)
PAKFEKLM_02353 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
PAKFEKLM_02354 2.5e-140 endA F DNA RNA non-specific endonuclease
PAKFEKLM_02355 2.6e-97 speG J Acetyltransferase (GNAT) domain
PAKFEKLM_02356 2.2e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
PAKFEKLM_02357 3.2e-111 2.7.1.89 M Phosphotransferase enzyme family
PAKFEKLM_02358 1.9e-220 S CAAX protease self-immunity
PAKFEKLM_02359 7.9e-307 ybiT S ABC transporter, ATP-binding protein
PAKFEKLM_02360 5.3e-147 3.1.3.102, 3.1.3.104 S hydrolase
PAKFEKLM_02361 0.0 S Predicted membrane protein (DUF2207)
PAKFEKLM_02362 0.0 uvrA3 L excinuclease ABC
PAKFEKLM_02363 3.3e-119 EGP Major facilitator Superfamily
PAKFEKLM_02364 8.7e-79 EGP Major facilitator Superfamily
PAKFEKLM_02365 1.2e-73 ropB K Helix-turn-helix XRE-family like proteins
PAKFEKLM_02366 5.3e-83 ropB K Helix-turn-helix XRE-family like proteins
PAKFEKLM_02367 1.7e-233 yxiO S Vacuole effluxer Atg22 like
PAKFEKLM_02368 1.7e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
PAKFEKLM_02369 2e-160 I alpha/beta hydrolase fold
PAKFEKLM_02370 4.8e-131 treR K UTRA
PAKFEKLM_02371 1.9e-238
PAKFEKLM_02372 5.6e-39 S Cytochrome B5
PAKFEKLM_02373 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PAKFEKLM_02374 1.5e-52 2.7.7.65 T Diguanylate cyclase, GGDEF domain
PAKFEKLM_02375 2.9e-151 2.7.7.65 T Diguanylate cyclase, GGDEF domain
PAKFEKLM_02376 1.2e-126 yliE T EAL domain
PAKFEKLM_02377 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PAKFEKLM_02378 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PAKFEKLM_02379 2e-80
PAKFEKLM_02380 4.9e-72 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PAKFEKLM_02381 3.7e-190 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PAKFEKLM_02382 3.4e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PAKFEKLM_02383 8.3e-22
PAKFEKLM_02384 4.4e-79
PAKFEKLM_02385 1.2e-163 K LysR substrate binding domain
PAKFEKLM_02386 3.4e-242 P Sodium:sulfate symporter transmembrane region
PAKFEKLM_02387 3.1e-286 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
PAKFEKLM_02388 4.1e-262 S response to antibiotic
PAKFEKLM_02389 4.1e-133 S zinc-ribbon domain
PAKFEKLM_02391 3.2e-37
PAKFEKLM_02392 8.2e-134 aroD S Alpha/beta hydrolase family
PAKFEKLM_02393 2.6e-176 S Phosphotransferase system, EIIC
PAKFEKLM_02394 5.7e-269 I acetylesterase activity
PAKFEKLM_02395 2.2e-168 sdrF M Collagen binding domain
PAKFEKLM_02396 1.8e-44 sdrF M Collagen binding domain
PAKFEKLM_02397 5.3e-159 yicL EG EamA-like transporter family
PAKFEKLM_02398 4.4e-129 E lipolytic protein G-D-S-L family
PAKFEKLM_02399 1.1e-177 4.1.1.52 S Amidohydrolase
PAKFEKLM_02400 2.1e-111 K Transcriptional regulator C-terminal region
PAKFEKLM_02401 7.7e-39 3.6.4.12 K HxlR-like helix-turn-helix
PAKFEKLM_02402 1.7e-162 ypbG 2.7.1.2 GK ROK family
PAKFEKLM_02403 0.0 ybfG M peptidoglycan-binding domain-containing protein
PAKFEKLM_02404 5.6e-89
PAKFEKLM_02405 0.0 lmrA 3.6.3.44 V ABC transporter
PAKFEKLM_02406 5e-93 rmaB K Transcriptional regulator, MarR family
PAKFEKLM_02407 3.5e-158 ccpB 5.1.1.1 K lacI family
PAKFEKLM_02408 1.6e-119 yceE S haloacid dehalogenase-like hydrolase
PAKFEKLM_02409 3.8e-119 drgA C Nitroreductase family
PAKFEKLM_02410 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
PAKFEKLM_02411 2.9e-117 cmpC S ATPases associated with a variety of cellular activities
PAKFEKLM_02412 3.3e-154 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
PAKFEKLM_02413 1.1e-167 XK27_00670 S ABC transporter
PAKFEKLM_02414 2e-259
PAKFEKLM_02415 7.3e-62
PAKFEKLM_02416 5.1e-190 S Cell surface protein
PAKFEKLM_02417 3.3e-90 S WxL domain surface cell wall-binding
PAKFEKLM_02418 5.3e-63 acuB S Domain in cystathionine beta-synthase and other proteins.
PAKFEKLM_02419 1e-31 cp12 S Domain in cystathionine beta-synthase and other proteins.
PAKFEKLM_02420 3.3e-124 livF E ABC transporter
PAKFEKLM_02421 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
PAKFEKLM_02422 2.2e-139 livM E Branched-chain amino acid transport system / permease component
PAKFEKLM_02423 1.1e-153 livH U Branched-chain amino acid transport system / permease component
PAKFEKLM_02424 5.4e-212 livJ E Receptor family ligand binding region
PAKFEKLM_02426 7e-33
PAKFEKLM_02427 3.3e-112 zmp3 O Zinc-dependent metalloprotease
PAKFEKLM_02428 2.8e-82 gtrA S GtrA-like protein
PAKFEKLM_02429 6.1e-122 K Helix-turn-helix XRE-family like proteins
PAKFEKLM_02430 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
PAKFEKLM_02431 6.8e-72 T Belongs to the universal stress protein A family
PAKFEKLM_02432 1.1e-46
PAKFEKLM_02433 1.9e-116 S SNARE associated Golgi protein
PAKFEKLM_02434 2e-49 K Transcriptional regulator, ArsR family
PAKFEKLM_02435 1.2e-95 cadD P Cadmium resistance transporter
PAKFEKLM_02436 0.0 yhcA V ABC transporter, ATP-binding protein
PAKFEKLM_02437 0.0 P Concanavalin A-like lectin/glucanases superfamily
PAKFEKLM_02438 7.4e-64
PAKFEKLM_02439 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
PAKFEKLM_02440 3.2e-55
PAKFEKLM_02441 5.3e-150 dicA K Helix-turn-helix domain
PAKFEKLM_02442 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PAKFEKLM_02443 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PAKFEKLM_02444 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_02445 8.3e-281 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PAKFEKLM_02446 4.4e-186 1.1.1.219 GM Male sterility protein
PAKFEKLM_02447 5.1e-75 K helix_turn_helix, mercury resistance
PAKFEKLM_02448 4.3e-64 M LysM domain
PAKFEKLM_02449 9.7e-94 M Lysin motif
PAKFEKLM_02450 4.7e-108 S SdpI/YhfL protein family
PAKFEKLM_02451 1.8e-54 nudA S ASCH
PAKFEKLM_02452 1.7e-162 psaA P Belongs to the bacterial solute-binding protein 9 family
PAKFEKLM_02453 4.7e-91
PAKFEKLM_02454 1.2e-120 tag 3.2.2.20 L Methyladenine glycosylase
PAKFEKLM_02455 2.1e-213 T diguanylate cyclase
PAKFEKLM_02456 5.3e-69 S Psort location Cytoplasmic, score
PAKFEKLM_02457 2.2e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
PAKFEKLM_02458 1.1e-46 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PAKFEKLM_02459 2.1e-121 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PAKFEKLM_02460 3.8e-29
PAKFEKLM_02461 2.3e-47 adhR K helix_turn_helix, mercury resistance
PAKFEKLM_02462 9.3e-37 fldA C Flavodoxin
PAKFEKLM_02463 1.3e-150 S Hydrolases of the alpha beta superfamily
PAKFEKLM_02464 3.1e-136 C Aldo/keto reductase family
PAKFEKLM_02465 2.1e-80 GM NmrA-like family
PAKFEKLM_02466 8e-52 darA C Flavodoxin
PAKFEKLM_02467 1.5e-270 L Transposase
PAKFEKLM_02468 1.1e-08 C Flavodoxin
PAKFEKLM_02469 4.5e-60 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PAKFEKLM_02470 6e-78 S X-Pro dipeptidyl-peptidase (S15 family)
PAKFEKLM_02471 7.9e-44 K Bacterial regulatory proteins, tetR family
PAKFEKLM_02472 5.8e-166 K Bacterial regulatory helix-turn-helix protein, lysR family
PAKFEKLM_02473 2e-73
PAKFEKLM_02474 8.5e-131 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PAKFEKLM_02475 1.6e-175 C C4-dicarboxylate transmembrane transporter activity
PAKFEKLM_02476 1.6e-117 GM NAD(P)H-binding
PAKFEKLM_02477 3.4e-91 S Phosphatidylethanolamine-binding protein
PAKFEKLM_02478 2.7e-78 yphH S Cupin domain
PAKFEKLM_02479 3.7e-60 I sulfurtransferase activity
PAKFEKLM_02480 1.6e-137 IQ reductase
PAKFEKLM_02481 8e-117 GM NAD(P)H-binding
PAKFEKLM_02482 4.3e-217 ykiI
PAKFEKLM_02483 3.5e-266 V ABC transporter
PAKFEKLM_02484 8.5e-57 V ABC transporter
PAKFEKLM_02485 1.7e-310 XK27_09600 V ABC transporter, ATP-binding protein
PAKFEKLM_02486 6.6e-226 amd 3.5.1.47 E Peptidase family M20/M25/M40
PAKFEKLM_02487 7.7e-163 IQ KR domain
PAKFEKLM_02489 7.4e-71
PAKFEKLM_02490 1.9e-144 K Helix-turn-helix XRE-family like proteins
PAKFEKLM_02491 1.4e-265 yjeM E Amino Acid
PAKFEKLM_02492 3.9e-66 lysM M LysM domain
PAKFEKLM_02493 5.4e-77 L Transposase DDE domain
PAKFEKLM_02494 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_02495 1.1e-222 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
PAKFEKLM_02496 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PAKFEKLM_02497 0.0 ctpA 3.6.3.54 P P-type ATPase
PAKFEKLM_02498 6.4e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PAKFEKLM_02499 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PAKFEKLM_02500 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PAKFEKLM_02501 6e-140 K Helix-turn-helix domain
PAKFEKLM_02502 2.9e-38 S TfoX C-terminal domain
PAKFEKLM_02503 1e-227 hpk9 2.7.13.3 T GHKL domain
PAKFEKLM_02504 1.8e-84
PAKFEKLM_02505 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_02506 2e-76 L Transposase DDE domain
PAKFEKLM_02507 5.7e-167
PAKFEKLM_02508 1.3e-75
PAKFEKLM_02509 1.5e-189 S Cell surface protein
PAKFEKLM_02510 1.7e-101 S WxL domain surface cell wall-binding
PAKFEKLM_02511 1.9e-175 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
PAKFEKLM_02512 3.8e-69 S Iron-sulphur cluster biosynthesis
PAKFEKLM_02513 7.3e-115 S GyrI-like small molecule binding domain
PAKFEKLM_02514 6.9e-184 S Cell surface protein
PAKFEKLM_02515 2e-101 S WxL domain surface cell wall-binding
PAKFEKLM_02516 1.1e-62
PAKFEKLM_02517 9.8e-217 NU Mycoplasma protein of unknown function, DUF285
PAKFEKLM_02518 5.9e-117
PAKFEKLM_02519 3e-116 S Haloacid dehalogenase-like hydrolase
PAKFEKLM_02520 2e-61 K Transcriptional regulator, HxlR family
PAKFEKLM_02521 1.4e-212 ytbD EGP Major facilitator Superfamily
PAKFEKLM_02522 1.4e-94 M ErfK YbiS YcfS YnhG
PAKFEKLM_02523 0.0 asnB 6.3.5.4 E Asparagine synthase
PAKFEKLM_02524 4.5e-132 K LytTr DNA-binding domain
PAKFEKLM_02525 3e-205 2.7.13.3 T GHKL domain
PAKFEKLM_02526 8.2e-97 fadR K Bacterial regulatory proteins, tetR family
PAKFEKLM_02527 1.8e-167 GM NmrA-like family
PAKFEKLM_02528 1e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PAKFEKLM_02529 2.1e-273 M Glycosyl hydrolases family 25
PAKFEKLM_02530 7.2e-38 M Glycosyl hydrolases family 25
PAKFEKLM_02531 1.1e-46 S Domain of unknown function (DUF1905)
PAKFEKLM_02532 1.1e-62 hxlR K HxlR-like helix-turn-helix
PAKFEKLM_02533 9.8e-132 ydfG S KR domain
PAKFEKLM_02534 8e-97 K Bacterial regulatory proteins, tetR family
PAKFEKLM_02535 1.2e-191 1.1.1.219 GM Male sterility protein
PAKFEKLM_02536 4.1e-101 S Protein of unknown function (DUF1211)
PAKFEKLM_02537 4.8e-179 S Aldo keto reductase
PAKFEKLM_02538 1.6e-253 yfjF U Sugar (and other) transporter
PAKFEKLM_02539 7.4e-109 K Bacterial regulatory proteins, tetR family
PAKFEKLM_02540 2.2e-168 fhuD P Periplasmic binding protein
PAKFEKLM_02541 1.1e-144 fhuC 3.6.3.34 HP ABC transporter
PAKFEKLM_02542 9.5e-178 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAKFEKLM_02543 8.6e-171 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAKFEKLM_02544 5.4e-92 K Bacterial regulatory proteins, tetR family
PAKFEKLM_02545 1.4e-156 GM NmrA-like family
PAKFEKLM_02546 7.2e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PAKFEKLM_02547 6.3e-68 maa S transferase hexapeptide repeat
PAKFEKLM_02548 2.9e-151 IQ Enoyl-(Acyl carrier protein) reductase
PAKFEKLM_02549 3.9e-63 K helix_turn_helix, mercury resistance
PAKFEKLM_02550 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
PAKFEKLM_02551 2.3e-69 tnp2PF3 L manually curated
PAKFEKLM_02552 7.4e-14 pelX UW LPXTG-motif cell wall anchor domain protein
PAKFEKLM_02553 4.9e-83 S Bacterial protein of unknown function (DUF916)
PAKFEKLM_02554 9.4e-75 S Bacterial protein of unknown function (DUF916)
PAKFEKLM_02555 4.3e-90 S WxL domain surface cell wall-binding
PAKFEKLM_02556 1.2e-183 NU Mycoplasma protein of unknown function, DUF285
PAKFEKLM_02557 8.1e-117 K Bacterial regulatory proteins, tetR family
PAKFEKLM_02558 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PAKFEKLM_02559 3.6e-288 yjcE P Sodium proton antiporter
PAKFEKLM_02560 5.7e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
PAKFEKLM_02561 6.2e-160 K LysR substrate binding domain
PAKFEKLM_02562 8.9e-281 1.3.5.4 C FAD binding domain
PAKFEKLM_02563 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
PAKFEKLM_02564 1.7e-84 dps P Belongs to the Dps family
PAKFEKLM_02565 2.2e-115 K UTRA
PAKFEKLM_02566 1.2e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PAKFEKLM_02567 7.7e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_02568 4.1e-65
PAKFEKLM_02569 1.5e-11
PAKFEKLM_02570 9.4e-41 4.1.1.44 S Carboxymuconolactone decarboxylase family
PAKFEKLM_02571 1.3e-23 rmeD K helix_turn_helix, mercury resistance
PAKFEKLM_02572 7.6e-64 S Protein of unknown function (DUF1093)
PAKFEKLM_02573 1.4e-205 S Membrane
PAKFEKLM_02574 6.3e-221 L Transposase
PAKFEKLM_02575 1.4e-46 K Helix-turn-helix domain
PAKFEKLM_02576 8.8e-91 S ABC-2 family transporter protein
PAKFEKLM_02577 1.4e-52 S ABC-2 family transporter protein
PAKFEKLM_02578 6e-91 V ABC transporter, ATP-binding protein
PAKFEKLM_02579 8.8e-40
PAKFEKLM_02580 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PAKFEKLM_02581 4.9e-172 K AI-2E family transporter
PAKFEKLM_02582 1.7e-210 xylR GK ROK family
PAKFEKLM_02583 2.3e-81
PAKFEKLM_02584 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PAKFEKLM_02585 3.9e-162
PAKFEKLM_02586 3.2e-200 KLT Protein tyrosine kinase
PAKFEKLM_02587 2.9e-23 S Protein of unknown function (DUF4064)
PAKFEKLM_02588 6e-97 S Domain of unknown function (DUF4352)
PAKFEKLM_02589 1.5e-74 S Psort location Cytoplasmic, score
PAKFEKLM_02590 5.4e-77 L Transposase DDE domain
PAKFEKLM_02591 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_02592 7.5e-30
PAKFEKLM_02593 1.1e-100 S membrane transporter protein
PAKFEKLM_02594 2.3e-54 azlD S branched-chain amino acid
PAKFEKLM_02595 7.4e-130 azlC E branched-chain amino acid
PAKFEKLM_02596 2.9e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
PAKFEKLM_02597 7.1e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PAKFEKLM_02598 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
PAKFEKLM_02599 3.2e-124 K response regulator
PAKFEKLM_02600 2.7e-123 yoaK S Protein of unknown function (DUF1275)
PAKFEKLM_02601 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PAKFEKLM_02602 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PAKFEKLM_02603 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
PAKFEKLM_02604 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PAKFEKLM_02605 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
PAKFEKLM_02606 2.4e-156 spo0J K Belongs to the ParB family
PAKFEKLM_02607 1.8e-136 soj D Sporulation initiation inhibitor
PAKFEKLM_02608 7.9e-149 noc K Belongs to the ParB family
PAKFEKLM_02609 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PAKFEKLM_02610 4.1e-226 nupG F Nucleoside
PAKFEKLM_02611 2.5e-22 S Bacterial membrane protein YfhO
PAKFEKLM_02612 4e-29 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_02613 9.8e-38 tnp2PF3 L Transposase DDE domain
PAKFEKLM_02614 0.0 S Bacterial membrane protein YfhO
PAKFEKLM_02615 3.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
PAKFEKLM_02616 2.1e-168 K LysR substrate binding domain
PAKFEKLM_02617 1.9e-236 EK Aminotransferase, class I
PAKFEKLM_02618 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PAKFEKLM_02619 8.1e-123 tcyB E ABC transporter
PAKFEKLM_02620 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PAKFEKLM_02621 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PAKFEKLM_02622 4e-55 KT response to antibiotic
PAKFEKLM_02623 1.7e-16 KT response to antibiotic
PAKFEKLM_02624 9.8e-52 K Transcriptional regulator
PAKFEKLM_02625 2.2e-71 XK27_06920 S Protein of unknown function (DUF1700)
PAKFEKLM_02626 7.2e-119 S Putative adhesin
PAKFEKLM_02627 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
PAKFEKLM_02628 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PAKFEKLM_02629 1.2e-180 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
PAKFEKLM_02630 2.6e-205 S DUF218 domain
PAKFEKLM_02631 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
PAKFEKLM_02632 1.4e-116 ybbL S ABC transporter, ATP-binding protein
PAKFEKLM_02633 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PAKFEKLM_02634 9.4e-77
PAKFEKLM_02635 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
PAKFEKLM_02636 4.2e-147 cof S haloacid dehalogenase-like hydrolase
PAKFEKLM_02637 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PAKFEKLM_02638 2.6e-307 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
PAKFEKLM_02639 3.7e-84 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
PAKFEKLM_02640 4.8e-26 mngA 2.7.1.195, 2.7.1.202 G the current gene model (or a revised gene model) may contain a
PAKFEKLM_02641 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
PAKFEKLM_02642 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PAKFEKLM_02643 1.3e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PAKFEKLM_02644 2e-77 merR K MerR family regulatory protein
PAKFEKLM_02645 9e-156 1.6.5.2 GM NmrA-like family
PAKFEKLM_02646 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
PAKFEKLM_02647 1.1e-126 magIII L Base excision DNA repair protein, HhH-GPD family
PAKFEKLM_02648 1.4e-08
PAKFEKLM_02649 1.4e-22 S NADPH-dependent FMN reductase
PAKFEKLM_02650 2.1e-64 S NADPH-dependent FMN reductase
PAKFEKLM_02651 2.3e-237 S module of peptide synthetase
PAKFEKLM_02652 6.9e-107
PAKFEKLM_02653 9.8e-88 perR P Belongs to the Fur family
PAKFEKLM_02654 6.4e-41 S Enterocin A Immunity
PAKFEKLM_02655 9.7e-222 L Transposase
PAKFEKLM_02656 5.4e-36 S Phospholipase_D-nuclease N-terminal
PAKFEKLM_02657 9.9e-134 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
PAKFEKLM_02658 1.2e-24 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
PAKFEKLM_02659 3.8e-104 J Acetyltransferase (GNAT) domain
PAKFEKLM_02660 4.3e-63 lrgA S LrgA family
PAKFEKLM_02661 7.3e-127 lrgB M LrgB-like family
PAKFEKLM_02662 2.5e-145 DegV S EDD domain protein, DegV family
PAKFEKLM_02663 1.2e-24
PAKFEKLM_02664 3.5e-118 yugP S Putative neutral zinc metallopeptidase
PAKFEKLM_02665 2.9e-295 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
PAKFEKLM_02666 5.8e-163 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
PAKFEKLM_02667 1.7e-184 D Alpha beta
PAKFEKLM_02668 6e-197 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PAKFEKLM_02669 9.5e-258 gor 1.8.1.7 C Glutathione reductase
PAKFEKLM_02670 1.7e-54 S Enterocin A Immunity
PAKFEKLM_02671 1.1e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PAKFEKLM_02672 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PAKFEKLM_02673 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PAKFEKLM_02674 2.7e-142 oppF E Oligopeptide/dipeptide transporter, C-terminal region
PAKFEKLM_02675 3.4e-189 oppD P Belongs to the ABC transporter superfamily
PAKFEKLM_02676 1.5e-156 amiD EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PAKFEKLM_02677 1.6e-258 amiC U Binding-protein-dependent transport system inner membrane component
PAKFEKLM_02678 0.0 amiA E Bacterial extracellular solute-binding proteins, family 5 Middle
PAKFEKLM_02679 6.4e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
PAKFEKLM_02680 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAKFEKLM_02682 2.1e-82
PAKFEKLM_02683 2.3e-257 yhdG E C-terminus of AA_permease
PAKFEKLM_02685 0.0 kup P Transport of potassium into the cell
PAKFEKLM_02686 3.9e-165 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAKFEKLM_02687 3.1e-179 K AI-2E family transporter
PAKFEKLM_02688 3.4e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
PAKFEKLM_02689 4.4e-59 qacC P Small Multidrug Resistance protein
PAKFEKLM_02690 1.1e-44 qacH U Small Multidrug Resistance protein
PAKFEKLM_02691 3e-116 hly S protein, hemolysin III
PAKFEKLM_02692 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
PAKFEKLM_02693 2.7e-160 czcD P cation diffusion facilitator family transporter
PAKFEKLM_02694 7.8e-103 K Helix-turn-helix XRE-family like proteins
PAKFEKLM_02696 2.6e-19
PAKFEKLM_02697 3.2e-95 tag 3.2.2.20 L glycosylase
PAKFEKLM_02698 6.1e-213 folP 2.5.1.15 H dihydropteroate synthase
PAKFEKLM_02699 4e-99 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
PAKFEKLM_02700 3.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PAKFEKLM_02701 7.5e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
PAKFEKLM_02702 1.2e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PAKFEKLM_02703 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PAKFEKLM_02704 1.5e-81 cvpA S Colicin V production protein
PAKFEKLM_02705 1.3e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
PAKFEKLM_02706 1.3e-249 EGP Major facilitator Superfamily
PAKFEKLM_02708 7e-40
PAKFEKLM_02709 1.5e-42 S COG NOG38524 non supervised orthologous group
PAKFEKLM_02710 6.2e-96 V VanZ like family
PAKFEKLM_02711 2.1e-193 blaA6 V Beta-lactamase
PAKFEKLM_02712 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
PAKFEKLM_02713 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PAKFEKLM_02714 5.1e-53 yitW S Pfam:DUF59
PAKFEKLM_02715 1.7e-173 S Aldo keto reductase
PAKFEKLM_02716 3.3e-97 FG HIT domain
PAKFEKLM_02717 9e-37 S Bacteriocin-protection, YdeI or OmpD-Associated
PAKFEKLM_02718 1.4e-77
PAKFEKLM_02719 2e-120 E GDSL-like Lipase/Acylhydrolase family
PAKFEKLM_02720 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
PAKFEKLM_02721 0.0 cadA P P-type ATPase
PAKFEKLM_02723 4.8e-125 yyaQ S YjbR
PAKFEKLM_02724 7.7e-219 S Uncharacterized protein conserved in bacteria (DUF2325)
PAKFEKLM_02725 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PAKFEKLM_02726 1.3e-199 frlB M SIS domain
PAKFEKLM_02727 6.1e-27 3.2.2.10 S Belongs to the LOG family
PAKFEKLM_02728 1.2e-255 nhaC C Na H antiporter NhaC
PAKFEKLM_02729 3.1e-251 cycA E Amino acid permease
PAKFEKLM_02730 3.7e-168 S Alpha/beta hydrolase of unknown function (DUF915)
PAKFEKLM_02731 1.6e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
PAKFEKLM_02732 3.8e-119 azoB GM NmrA-like family
PAKFEKLM_02733 4.3e-32 azoB GM NmrA-like family
PAKFEKLM_02734 5.4e-66 K Winged helix DNA-binding domain
PAKFEKLM_02735 7e-71 spx4 1.20.4.1 P ArsC family
PAKFEKLM_02736 1.7e-66 yeaO S Protein of unknown function, DUF488
PAKFEKLM_02737 4e-53
PAKFEKLM_02738 1.5e-213 mutY L A G-specific adenine glycosylase
PAKFEKLM_02739 9.2e-62
PAKFEKLM_02740 1.6e-83
PAKFEKLM_02741 1.3e-78 hsp3 O Belongs to the small heat shock protein (HSP20) family
PAKFEKLM_02742 1e-54
PAKFEKLM_02743 2.1e-14
PAKFEKLM_02744 1.1e-115 GM NmrA-like family
PAKFEKLM_02745 1.3e-81 elaA S GNAT family
PAKFEKLM_02746 5.9e-158 EG EamA-like transporter family
PAKFEKLM_02747 1.8e-119 S membrane
PAKFEKLM_02748 6.8e-111 S VIT family
PAKFEKLM_02749 1.1e-189 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PAKFEKLM_02750 0.0 copB 3.6.3.4 P P-type ATPase
PAKFEKLM_02751 4.7e-73 copR K Copper transport repressor CopY TcrY
PAKFEKLM_02752 7.4e-40
PAKFEKLM_02753 7.7e-73 S COG NOG18757 non supervised orthologous group
PAKFEKLM_02754 1.5e-248 lmrB EGP Major facilitator Superfamily
PAKFEKLM_02755 3.4e-25
PAKFEKLM_02756 4.2e-49
PAKFEKLM_02757 1.6e-64 ycgX S Protein of unknown function (DUF1398)
PAKFEKLM_02758 1.2e-250 U Belongs to the purine-cytosine permease (2.A.39) family
PAKFEKLM_02759 5.9e-214 mdtG EGP Major facilitator Superfamily
PAKFEKLM_02760 6.8e-181 D Alpha beta
PAKFEKLM_02761 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
PAKFEKLM_02762 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PAKFEKLM_02763 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
PAKFEKLM_02764 9.5e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PAKFEKLM_02765 8.4e-152 ywkB S Membrane transport protein
PAKFEKLM_02766 5.2e-164 yvgN C Aldo keto reductase
PAKFEKLM_02767 9.2e-133 thrE S Putative threonine/serine exporter
PAKFEKLM_02768 1.6e-37 S Threonine/Serine exporter, ThrE
PAKFEKLM_02769 2.3e-43 S Protein of unknown function (DUF1093)
PAKFEKLM_02770 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PAKFEKLM_02771 2.7e-91 ymdB S Macro domain protein
PAKFEKLM_02772 1.2e-95 K transcriptional regulator
PAKFEKLM_02773 5.5e-50 yvlA
PAKFEKLM_02774 1.3e-160 ypuA S Protein of unknown function (DUF1002)
PAKFEKLM_02775 0.0
PAKFEKLM_02776 2.9e-185 S Bacterial protein of unknown function (DUF916)
PAKFEKLM_02777 1.7e-129 S WxL domain surface cell wall-binding
PAKFEKLM_02778 6.7e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
PAKFEKLM_02779 3.5e-88 K Winged helix DNA-binding domain
PAKFEKLM_02780 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
PAKFEKLM_02781 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
PAKFEKLM_02782 1.8e-27
PAKFEKLM_02783 2.8e-284 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PAKFEKLM_02784 1.3e-71 mltD CBM50 M PFAM NLP P60 protein
PAKFEKLM_02785 2.5e-53
PAKFEKLM_02786 1.6e-61
PAKFEKLM_02788 2.6e-65
PAKFEKLM_02789 1.7e-07 4.1.1.46 S metal-dependent hydrolase of the TIM-barrel fold
PAKFEKLM_02790 4.6e-100 K transcriptional regulator
PAKFEKLM_02791 6.1e-28 yfeX P Peroxidase
PAKFEKLM_02792 1.4e-121 yfeX P Peroxidase
PAKFEKLM_02793 3.8e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PAKFEKLM_02794 6.3e-128 ydcF S Gram-negative-bacterium-type cell wall biogenesis
PAKFEKLM_02795 1.1e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
PAKFEKLM_02796 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PAKFEKLM_02797 1.1e-141 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PAKFEKLM_02798 4.7e-54 txlA O Thioredoxin-like domain
PAKFEKLM_02799 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
PAKFEKLM_02800 1.6e-18
PAKFEKLM_02801 1.1e-95 dps P Belongs to the Dps family
PAKFEKLM_02802 1.6e-32 copZ P Heavy-metal-associated domain
PAKFEKLM_02803 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
PAKFEKLM_02804 0.0 pepO 3.4.24.71 O Peptidase family M13
PAKFEKLM_02805 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PAKFEKLM_02806 1.3e-262 nox C NADH oxidase
PAKFEKLM_02807 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
PAKFEKLM_02808 1.2e-164 S Cell surface protein
PAKFEKLM_02809 1e-117 S WxL domain surface cell wall-binding
PAKFEKLM_02810 2.3e-99 S WxL domain surface cell wall-binding
PAKFEKLM_02811 4.6e-45
PAKFEKLM_02812 7.7e-103 K Bacterial regulatory proteins, tetR family
PAKFEKLM_02813 1.5e-49
PAKFEKLM_02814 5.2e-248 S Putative metallopeptidase domain
PAKFEKLM_02815 1.6e-219 3.1.3.1 S associated with various cellular activities
PAKFEKLM_02816 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
PAKFEKLM_02817 0.0 ubiB S ABC1 family
PAKFEKLM_02818 6.4e-249 brnQ U Component of the transport system for branched-chain amino acids
PAKFEKLM_02819 1.8e-199 lacA 3.2.1.23 G -beta-galactosidase
PAKFEKLM_02820 5.3e-220 L Transposase
PAKFEKLM_02821 7.1e-172 lacA 3.2.1.23 G -beta-galactosidase
PAKFEKLM_02822 0.0 rafA 3.2.1.22 G alpha-galactosidase
PAKFEKLM_02823 2.2e-68 S Domain of unknown function (DUF3284)
PAKFEKLM_02824 7.9e-233 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_02825 6.8e-179 galR K Periplasmic binding protein-like domain
PAKFEKLM_02826 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PAKFEKLM_02827 8.1e-230 mdtH P Sugar (and other) transporter
PAKFEKLM_02828 1.5e-302 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PAKFEKLM_02829 8.6e-232 EGP Major facilitator Superfamily
PAKFEKLM_02830 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
PAKFEKLM_02831 7.4e-109 fic D Fic/DOC family
PAKFEKLM_02832 1.6e-76 K Helix-turn-helix XRE-family like proteins
PAKFEKLM_02833 2e-183 galR K Transcriptional regulator
PAKFEKLM_02834 1.3e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PAKFEKLM_02835 3.1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PAKFEKLM_02836 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PAKFEKLM_02837 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PAKFEKLM_02838 4.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
PAKFEKLM_02839 0.0 rafA 3.2.1.22 G alpha-galactosidase
PAKFEKLM_02840 0.0 lacS G Transporter
PAKFEKLM_02841 2.7e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PAKFEKLM_02842 2.4e-173 galR K Transcriptional regulator
PAKFEKLM_02843 2.6e-194 C Aldo keto reductase family protein
PAKFEKLM_02844 2.4e-65 S pyridoxamine 5-phosphate
PAKFEKLM_02845 0.0 1.3.5.4 C FAD binding domain
PAKFEKLM_02846 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PAKFEKLM_02847 2.4e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PAKFEKLM_02848 9.7e-166 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PAKFEKLM_02849 9.2e-175 K Transcriptional regulator, LysR family
PAKFEKLM_02850 1.2e-219 ydiN EGP Major Facilitator Superfamily
PAKFEKLM_02851 1.9e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PAKFEKLM_02852 1.2e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PAKFEKLM_02853 1e-156 IQ Enoyl-(Acyl carrier protein) reductase
PAKFEKLM_02854 2.1e-165 G Xylose isomerase-like TIM barrel
PAKFEKLM_02855 4.7e-168 K Transcriptional regulator, LysR family
PAKFEKLM_02856 1.2e-201 EGP Major Facilitator Superfamily
PAKFEKLM_02857 2.9e-63
PAKFEKLM_02858 1.8e-155 estA S Putative esterase
PAKFEKLM_02859 1.2e-134 K UTRA domain
PAKFEKLM_02860 1.4e-248 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKFEKLM_02861 2.6e-164 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PAKFEKLM_02862 1.7e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
PAKFEKLM_02863 2.4e-211 S Bacterial protein of unknown function (DUF871)
PAKFEKLM_02864 5.4e-77 L Transposase DDE domain
PAKFEKLM_02865 1.8e-68 L Putative transposase of IS4/5 family (DUF4096)
PAKFEKLM_02866 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PAKFEKLM_02867 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
PAKFEKLM_02868 4.2e-70 S Pyrimidine dimer DNA glycosylase
PAKFEKLM_02869 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
PAKFEKLM_02870 3.6e-11
PAKFEKLM_02871 9e-13 ytgB S Transglycosylase associated protein
PAKFEKLM_02872 5.4e-291 katA 1.11.1.6 C Belongs to the catalase family
PAKFEKLM_02873 4.9e-78 yneH 1.20.4.1 K ArsC family
PAKFEKLM_02874 7.4e-135 K LytTr DNA-binding domain
PAKFEKLM_02875 1.5e-159 2.7.13.3 T GHKL domain
PAKFEKLM_02876 1.8e-12
PAKFEKLM_02877 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
PAKFEKLM_02878 6.3e-221 L Transposase
PAKFEKLM_02879 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
PAKFEKLM_02881 7.5e-200 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PAKFEKLM_02882 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PAKFEKLM_02883 5.7e-71 K Transcriptional regulator
PAKFEKLM_02884 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PAKFEKLM_02885 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PAKFEKLM_02886 1.5e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
PAKFEKLM_02887 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
PAKFEKLM_02888 1.1e-86 gutM K Glucitol operon activator protein (GutM)
PAKFEKLM_02889 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
PAKFEKLM_02890 3.8e-145 IQ NAD dependent epimerase/dehydratase family
PAKFEKLM_02891 2.8e-79 rbsU U ribose uptake protein RbsU
PAKFEKLM_02892 3.5e-64 rbsU U ribose uptake protein RbsU
PAKFEKLM_02893 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PAKFEKLM_02894 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAKFEKLM_02895 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
PAKFEKLM_02896 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PAKFEKLM_02897 2.7e-79 T Universal stress protein family
PAKFEKLM_02898 2.2e-99 padR K Virulence activator alpha C-term
PAKFEKLM_02899 1.7e-104 padC Q Phenolic acid decarboxylase
PAKFEKLM_02900 3.2e-144 tesE Q hydratase
PAKFEKLM_02901 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
PAKFEKLM_02902 1.2e-157 degV S DegV family
PAKFEKLM_02903 2.9e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
PAKFEKLM_02904 3.2e-169 pepC 3.4.22.40 E aminopeptidase
PAKFEKLM_02905 2.9e-66 pepC 3.4.22.40 E aminopeptidase
PAKFEKLM_02907 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PAKFEKLM_02908 7.3e-103
PAKFEKLM_02909 5e-173
PAKFEKLM_02911 1.2e-159 S Bacterial protein of unknown function (DUF916)
PAKFEKLM_02912 6.9e-93 S Cell surface protein
PAKFEKLM_02913 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PAKFEKLM_02914 3e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PAKFEKLM_02915 2.5e-130 jag S R3H domain protein
PAKFEKLM_02916 9.3e-239 Q Imidazolonepropionase and related amidohydrolases
PAKFEKLM_02917 2.7e-310 E ABC transporter, substratebinding protein
PAKFEKLM_02918 1.2e-104 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PAKFEKLM_02919 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)