ORF_ID e_value Gene_name EC_number CAZy COGs Description
NCMBECOF_00002 9.3e-272 pipD E Dipeptidase
NCMBECOF_00003 0.0 yjbQ P TrkA C-terminal domain protein
NCMBECOF_00004 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NCMBECOF_00005 3.5e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NCMBECOF_00006 7.9e-88
NCMBECOF_00007 1.1e-36
NCMBECOF_00008 9.6e-98 K DNA-templated transcription, initiation
NCMBECOF_00009 1.5e-95
NCMBECOF_00010 2.3e-66 K Transcriptional regulator, HxlR family
NCMBECOF_00011 1.5e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NCMBECOF_00012 1.8e-143 epsB M biosynthesis protein
NCMBECOF_00013 6.8e-120 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NCMBECOF_00014 1.8e-108 rfbP M Bacterial sugar transferase
NCMBECOF_00015 2.7e-160 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NCMBECOF_00016 4.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NCMBECOF_00017 1.6e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NCMBECOF_00018 7.9e-142 rgpAc GT4 M Domain of unknown function (DUF1972)
NCMBECOF_00019 8.7e-114 wcoF M Glycosyltransferase Family 4
NCMBECOF_00020 8.1e-110 cps3B S Glycosyltransferase like family 2
NCMBECOF_00021 4.7e-71 M Glycosyltransferase group 2 family protein
NCMBECOF_00022 1.9e-51 cysE 2.3.1.30 E Hexapeptide repeat of succinyl-transferase
NCMBECOF_00023 5.3e-53 S O-antigen ligase like membrane protein
NCMBECOF_00024 1.1e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
NCMBECOF_00025 6.2e-162 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NCMBECOF_00026 1e-114 M Glycosyl transferases group 1
NCMBECOF_00027 9.6e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NCMBECOF_00028 9.2e-56 S Protein of unknown function DUF262
NCMBECOF_00029 5.3e-26
NCMBECOF_00030 3e-100 V site-specific DNA-methyltransferase (adenine-specific) activity
NCMBECOF_00031 1e-98 busR K UTRA
NCMBECOF_00032 9.2e-165 yegU O ADP-ribosylglycohydrolase
NCMBECOF_00033 7.1e-240 F Belongs to the purine-cytosine permease (2.A.39) family
NCMBECOF_00034 5.4e-116 G Belongs to the carbohydrate kinase PfkB family
NCMBECOF_00035 8.7e-71 L Reverse transcriptase (RNA-dependent DNA polymerase)
NCMBECOF_00037 2.7e-25
NCMBECOF_00038 4.6e-42 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NCMBECOF_00039 2.4e-53 YPO0284 GM NAD(P)H-binding
NCMBECOF_00041 1.1e-29 S Protein of unknown function (DUF4065)
NCMBECOF_00042 5.8e-88 doc
NCMBECOF_00043 1.8e-09
NCMBECOF_00044 2.1e-49 D nuclear chromosome segregation
NCMBECOF_00045 2.2e-44
NCMBECOF_00046 6.2e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NCMBECOF_00047 3.1e-251 mmuP E amino acid
NCMBECOF_00049 3.3e-67 T Toxin-antitoxin system, toxin component, MazF family
NCMBECOF_00050 1e-37
NCMBECOF_00052 0.0 snf 2.7.11.1 KL domain protein
NCMBECOF_00053 9.1e-144 ywqE 3.1.3.48 GM PHP domain protein
NCMBECOF_00054 1.1e-95 M Glycosyl hydrolases family 25
NCMBECOF_00055 4.6e-44 M Glycosyl hydrolases family 25
NCMBECOF_00056 1.6e-205 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NCMBECOF_00057 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NCMBECOF_00058 6.3e-51 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCMBECOF_00059 3e-93 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NCMBECOF_00060 1.4e-189 L PFAM Integrase catalytic region
NCMBECOF_00061 4.6e-91 L nuclease
NCMBECOF_00062 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NCMBECOF_00063 9.6e-71
NCMBECOF_00064 6.8e-104 fic D Fic/DOC family
NCMBECOF_00065 1.5e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NCMBECOF_00066 4.5e-192
NCMBECOF_00067 0.0
NCMBECOF_00068 0.0
NCMBECOF_00069 9.2e-25
NCMBECOF_00070 6.1e-57
NCMBECOF_00072 5.8e-112 lssY 3.6.1.27 I Acid phosphatase homologues
NCMBECOF_00073 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NCMBECOF_00074 6.7e-229 clcA_2 P Chloride transporter, ClC family
NCMBECOF_00075 3.3e-85 L PFAM transposase IS200-family protein
NCMBECOF_00076 5.2e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NCMBECOF_00077 7.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NCMBECOF_00078 4.6e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NCMBECOF_00079 5.2e-50
NCMBECOF_00080 0.0 S SEC-C Motif Domain Protein
NCMBECOF_00081 7.1e-121 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NCMBECOF_00082 9e-72
NCMBECOF_00083 4e-173
NCMBECOF_00084 3.8e-174 fecB P Periplasmic binding protein
NCMBECOF_00085 9.2e-136 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
NCMBECOF_00086 1.2e-129 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NCMBECOF_00087 7.3e-77 S Flavodoxin
NCMBECOF_00088 3.5e-62 moaE 2.8.1.12 H MoaE protein
NCMBECOF_00089 3.9e-32 moaD 2.8.1.12 H ThiS family
NCMBECOF_00090 1.5e-217 narK P Transporter, major facilitator family protein
NCMBECOF_00091 1.5e-142 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
NCMBECOF_00092 1.4e-173
NCMBECOF_00093 9.5e-19
NCMBECOF_00094 9.8e-115 nreC K PFAM regulatory protein LuxR
NCMBECOF_00095 4e-162 comP 2.7.13.3 F Sensor histidine kinase
NCMBECOF_00096 3e-44
NCMBECOF_00097 4.4e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NCMBECOF_00098 6.7e-76 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NCMBECOF_00099 6.5e-221 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
NCMBECOF_00100 5.2e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NCMBECOF_00101 3.4e-183 moeB 2.7.7.73, 2.7.7.80 H ThiF family
NCMBECOF_00102 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NCMBECOF_00103 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
NCMBECOF_00104 1.6e-97 narJ C nitrate reductase molybdenum cofactor assembly chaperone
NCMBECOF_00105 2.5e-129 narI 1.7.5.1 C Nitrate reductase
NCMBECOF_00106 3.6e-152 EG EamA-like transporter family
NCMBECOF_00107 4.2e-118 L Integrase
NCMBECOF_00108 7.9e-157 rssA S Phospholipase, patatin family
NCMBECOF_00109 2.4e-13 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NCMBECOF_00110 9.3e-221 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NCMBECOF_00111 1.1e-189 L PFAM Integrase catalytic region
NCMBECOF_00112 1.3e-201 xerS L Belongs to the 'phage' integrase family
NCMBECOF_00114 1.4e-107 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NCMBECOF_00115 3.7e-138 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NCMBECOF_00116 5.4e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NCMBECOF_00117 1.9e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NCMBECOF_00126 8.1e-55
NCMBECOF_00127 1.3e-114 frnE Q DSBA-like thioredoxin domain
NCMBECOF_00128 1.2e-188 L PFAM Integrase catalytic region
NCMBECOF_00129 9.1e-161 I alpha/beta hydrolase fold
NCMBECOF_00130 3.5e-15
NCMBECOF_00131 1.1e-110 L Helix-turn-helix domain
NCMBECOF_00132 1.2e-08
NCMBECOF_00134 3.2e-83 arpU S Phage transcriptional regulator, ArpU family
NCMBECOF_00139 9.7e-59
NCMBECOF_00140 4.1e-189 L Belongs to the 'phage' integrase family
NCMBECOF_00141 5.3e-119 L DnaD domain protein
NCMBECOF_00144 8e-15
NCMBECOF_00145 6.2e-60
NCMBECOF_00146 3.8e-51
NCMBECOF_00148 6.3e-10 K Helix-turn-helix XRE-family like proteins
NCMBECOF_00149 5.1e-79 3.4.21.88 K Peptidase S24-like
NCMBECOF_00150 2e-25
NCMBECOF_00152 8.1e-76
NCMBECOF_00153 9.1e-68 S Domain of unknown function (DUF4393)
NCMBECOF_00155 2.1e-94 L Belongs to the 'phage' integrase family
NCMBECOF_00157 9.8e-40 yrvD S Pfam:DUF1049
NCMBECOF_00158 1.6e-151 3.1.3.102, 3.1.3.104 S hydrolase
NCMBECOF_00159 3.1e-89 ntd 2.4.2.6 F Nucleoside
NCMBECOF_00160 1.8e-19
NCMBECOF_00161 3.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
NCMBECOF_00162 2.2e-70 S Protein of unknown function (DUF3290)
NCMBECOF_00163 8.6e-41 ybaN S Protein of unknown function (DUF454)
NCMBECOF_00164 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NCMBECOF_00165 4.6e-157 endA V DNA/RNA non-specific endonuclease
NCMBECOF_00166 1.3e-254 yifK E Amino acid permease
NCMBECOF_00168 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NCMBECOF_00169 1.2e-230 N Uncharacterized conserved protein (DUF2075)
NCMBECOF_00170 1.8e-122 S SNARE associated Golgi protein
NCMBECOF_00171 0.0 uvrA3 L excinuclease ABC, A subunit
NCMBECOF_00172 9.4e-53 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCMBECOF_00173 2.4e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCMBECOF_00174 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NCMBECOF_00175 1.1e-144 S DUF218 domain
NCMBECOF_00176 0.0 ubiB S ABC1 family
NCMBECOF_00177 1.5e-245 yhdP S Transporter associated domain
NCMBECOF_00178 4.2e-74 copY K Copper transport repressor CopY TcrY
NCMBECOF_00179 1.8e-121 EGP Major facilitator Superfamily
NCMBECOF_00180 7.6e-74 yeaL S UPF0756 membrane protein
NCMBECOF_00181 2e-38 yphH S Cupin domain
NCMBECOF_00182 4.8e-96 K Acetyltransferase (GNAT) domain
NCMBECOF_00183 1.3e-159 S Alpha beta hydrolase
NCMBECOF_00184 1.9e-158 gspA M family 8
NCMBECOF_00185 6.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NCMBECOF_00186 5.1e-82
NCMBECOF_00187 2.7e-160 degV S EDD domain protein, DegV family
NCMBECOF_00188 0.0 FbpA K Fibronectin-binding protein
NCMBECOF_00189 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NCMBECOF_00190 3.1e-206 carA 6.3.5.5 F Belongs to the CarA family
NCMBECOF_00191 5.3e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NCMBECOF_00192 3.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NCMBECOF_00193 1.5e-65 esbA S Family of unknown function (DUF5322)
NCMBECOF_00194 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
NCMBECOF_00195 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NCMBECOF_00196 7.7e-85 F Belongs to the NrdI family
NCMBECOF_00197 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NCMBECOF_00198 7.8e-100 ypsA S Belongs to the UPF0398 family
NCMBECOF_00199 1.3e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NCMBECOF_00200 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NCMBECOF_00201 1.4e-162 EG EamA-like transporter family
NCMBECOF_00202 4e-122 dnaD L DnaD domain protein
NCMBECOF_00203 1.3e-85 ypmB S Protein conserved in bacteria
NCMBECOF_00204 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NCMBECOF_00205 3.9e-173 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NCMBECOF_00206 9.3e-162 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NCMBECOF_00207 2.7e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NCMBECOF_00208 4.2e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NCMBECOF_00209 1.9e-89 S Protein of unknown function (DUF1440)
NCMBECOF_00210 0.0 rafA 3.2.1.22 G alpha-galactosidase
NCMBECOF_00211 3.3e-186 galR K Periplasmic binding protein-like domain
NCMBECOF_00212 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NCMBECOF_00213 2.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NCMBECOF_00214 3.4e-124 lrgB M LrgB-like family
NCMBECOF_00215 1.9e-66 lrgA S LrgA family
NCMBECOF_00216 2.1e-129 lytT K response regulator receiver
NCMBECOF_00217 1e-290 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
NCMBECOF_00218 6.8e-148 f42a O Band 7 protein
NCMBECOF_00219 2.9e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NCMBECOF_00220 1.9e-155 yitU 3.1.3.104 S hydrolase
NCMBECOF_00221 6e-38 S Cytochrome B5
NCMBECOF_00222 1.1e-113 nreC K PFAM regulatory protein LuxR
NCMBECOF_00223 1.6e-160 hipB K Helix-turn-helix
NCMBECOF_00224 2.8e-57 yitW S Iron-sulfur cluster assembly protein
NCMBECOF_00225 4.2e-272 sufB O assembly protein SufB
NCMBECOF_00226 3.2e-80 nifU C SUF system FeS assembly protein, NifU family
NCMBECOF_00227 2.3e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NCMBECOF_00228 4.6e-241 sufD O FeS assembly protein SufD
NCMBECOF_00229 6.5e-145 sufC O FeS assembly ATPase SufC
NCMBECOF_00230 1.2e-31 feoA P FeoA domain
NCMBECOF_00231 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NCMBECOF_00232 1.8e-270 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NCMBECOF_00233 2.5e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NCMBECOF_00234 1.3e-63 ydiI Q Thioesterase superfamily
NCMBECOF_00235 7.1e-109 yvrI K sigma factor activity
NCMBECOF_00236 5.6e-201 G Transporter, major facilitator family protein
NCMBECOF_00237 0.0 S Bacterial membrane protein YfhO
NCMBECOF_00238 6.6e-104 T Ion transport 2 domain protein
NCMBECOF_00239 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NCMBECOF_00240 1.6e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NCMBECOF_00241 7.4e-101 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NCMBECOF_00242 4.1e-195 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NCMBECOF_00243 1.7e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NCMBECOF_00245 0.0 L PLD-like domain
NCMBECOF_00246 8e-87 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NCMBECOF_00248 8e-53 yhaI S Protein of unknown function (DUF805)
NCMBECOF_00249 6.8e-92 L PFAM Integrase catalytic region
NCMBECOF_00250 1.6e-149 L PFAM Integrase catalytic region
NCMBECOF_00251 1.5e-43
NCMBECOF_00252 0.0 nylA 3.5.1.4 J Belongs to the amidase family
NCMBECOF_00253 1.6e-21
NCMBECOF_00254 4.2e-47
NCMBECOF_00255 4.9e-96 K Acetyltransferase (GNAT) domain
NCMBECOF_00256 8.5e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NCMBECOF_00257 2.5e-212 gntT EG Gluconate
NCMBECOF_00258 1.2e-183 K Transcriptional regulator, LacI family
NCMBECOF_00259 2.3e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NCMBECOF_00260 7.2e-95
NCMBECOF_00261 2.3e-24
NCMBECOF_00262 1.3e-61 asp S Asp23 family, cell envelope-related function
NCMBECOF_00263 3.8e-87 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NCMBECOF_00265 4.6e-49
NCMBECOF_00266 1.2e-67 yqkB S Belongs to the HesB IscA family
NCMBECOF_00267 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
NCMBECOF_00268 1.7e-81 F NUDIX domain
NCMBECOF_00269 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NCMBECOF_00270 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NCMBECOF_00271 2.8e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NCMBECOF_00272 6.7e-167 lacX 5.1.3.3 G Aldose 1-epimerase
NCMBECOF_00273 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NCMBECOF_00274 5.4e-161 dprA LU DNA protecting protein DprA
NCMBECOF_00275 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NCMBECOF_00276 8.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NCMBECOF_00277 4.4e-35 yozE S Belongs to the UPF0346 family
NCMBECOF_00278 2.2e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NCMBECOF_00279 1.8e-170 ypmR E lipolytic protein G-D-S-L family
NCMBECOF_00280 4.4e-152 DegV S EDD domain protein, DegV family
NCMBECOF_00281 5.3e-113 hlyIII S protein, hemolysin III
NCMBECOF_00282 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NCMBECOF_00283 8e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NCMBECOF_00284 0.0 yfmR S ABC transporter, ATP-binding protein
NCMBECOF_00285 3.1e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NCMBECOF_00286 4.4e-236 S Tetratricopeptide repeat protein
NCMBECOF_00287 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NCMBECOF_00288 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NCMBECOF_00289 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NCMBECOF_00290 2.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NCMBECOF_00291 2.5e-13 M Lysin motif
NCMBECOF_00292 3.1e-270 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NCMBECOF_00293 9.7e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
NCMBECOF_00294 2.6e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NCMBECOF_00295 4.9e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NCMBECOF_00296 8.5e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NCMBECOF_00297 8.4e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NCMBECOF_00298 1.8e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NCMBECOF_00299 1.3e-165 xerD D recombinase XerD
NCMBECOF_00300 9.3e-169 cvfB S S1 domain
NCMBECOF_00301 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NCMBECOF_00302 0.0 dnaE 2.7.7.7 L DNA polymerase
NCMBECOF_00303 2.3e-30 S Protein of unknown function (DUF2929)
NCMBECOF_00304 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NCMBECOF_00305 1.4e-155 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NCMBECOF_00306 9.2e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
NCMBECOF_00307 7e-220 patA 2.6.1.1 E Aminotransferase
NCMBECOF_00308 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NCMBECOF_00309 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NCMBECOF_00310 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NCMBECOF_00311 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NCMBECOF_00312 2.6e-146 recO L Involved in DNA repair and RecF pathway recombination
NCMBECOF_00313 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NCMBECOF_00314 1.1e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NCMBECOF_00315 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NCMBECOF_00316 7.6e-183 phoH T phosphate starvation-inducible protein PhoH
NCMBECOF_00317 6.6e-176 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NCMBECOF_00318 6.8e-88 bioY S BioY family
NCMBECOF_00319 2.4e-264 argH 4.3.2.1 E argininosuccinate lyase
NCMBECOF_00320 1.1e-236 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NCMBECOF_00321 3.8e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NCMBECOF_00322 5.6e-69 yqeY S YqeY-like protein
NCMBECOF_00323 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NCMBECOF_00324 2.8e-258 glnPH2 P ABC transporter permease
NCMBECOF_00325 5.3e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NCMBECOF_00326 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NCMBECOF_00327 1.8e-169 yniA G Phosphotransferase enzyme family
NCMBECOF_00328 4.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NCMBECOF_00329 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NCMBECOF_00330 1.2e-52
NCMBECOF_00331 3.2e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NCMBECOF_00332 1.2e-180 prmA J Ribosomal protein L11 methyltransferase
NCMBECOF_00333 7.5e-58
NCMBECOF_00334 2.3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NCMBECOF_00335 3.3e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NCMBECOF_00336 6.3e-276 pipD E Dipeptidase
NCMBECOF_00337 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NCMBECOF_00338 7.3e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NCMBECOF_00339 0.0 dnaK O Heat shock 70 kDa protein
NCMBECOF_00340 1.7e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NCMBECOF_00341 2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NCMBECOF_00342 2e-64
NCMBECOF_00343 1.3e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NCMBECOF_00344 4.4e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NCMBECOF_00345 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NCMBECOF_00346 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NCMBECOF_00347 3.8e-48 ylxQ J ribosomal protein
NCMBECOF_00348 1e-44 ylxR K Protein of unknown function (DUF448)
NCMBECOF_00349 1e-215 nusA K Participates in both transcription termination and antitermination
NCMBECOF_00350 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NCMBECOF_00351 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NCMBECOF_00352 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NCMBECOF_00353 1.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NCMBECOF_00354 7.6e-138 cdsA 2.7.7.41 I Belongs to the CDS family
NCMBECOF_00355 4.2e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NCMBECOF_00356 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NCMBECOF_00357 7.7e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NCMBECOF_00358 1.2e-152 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NCMBECOF_00359 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
NCMBECOF_00360 1.1e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCMBECOF_00361 7.1e-49 yazA L GIY-YIG catalytic domain protein
NCMBECOF_00362 5.4e-141 yabB 2.1.1.223 L Methyltransferase small domain
NCMBECOF_00363 6e-117 plsC 2.3.1.51 I Acyltransferase
NCMBECOF_00364 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
NCMBECOF_00365 1.3e-35 ynzC S UPF0291 protein
NCMBECOF_00366 3.6e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NCMBECOF_00367 1.4e-209 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NCMBECOF_00368 1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NCMBECOF_00370 1.6e-87
NCMBECOF_00371 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NCMBECOF_00372 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NCMBECOF_00373 3.2e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NCMBECOF_00374 1.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NCMBECOF_00375 1.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NCMBECOF_00376 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NCMBECOF_00377 7.6e-09
NCMBECOF_00378 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NCMBECOF_00379 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
NCMBECOF_00380 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NCMBECOF_00381 8.2e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NCMBECOF_00382 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NCMBECOF_00383 3.5e-163 S Tetratricopeptide repeat
NCMBECOF_00384 9.2e-264 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_00385 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NCMBECOF_00386 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NCMBECOF_00387 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
NCMBECOF_00388 6.1e-294 L Transposase
NCMBECOF_00389 5.3e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
NCMBECOF_00390 0.0 comEC S Competence protein ComEC
NCMBECOF_00391 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
NCMBECOF_00392 1.4e-78 comEA L Competence protein ComEA
NCMBECOF_00393 4.6e-199 ylbL T Belongs to the peptidase S16 family
NCMBECOF_00394 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NCMBECOF_00395 5.5e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NCMBECOF_00396 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NCMBECOF_00397 2e-222 ftsW D Belongs to the SEDS family
NCMBECOF_00398 0.0 typA T GTP-binding protein TypA
NCMBECOF_00399 1.8e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NCMBECOF_00400 1.4e-47 yktA S Belongs to the UPF0223 family
NCMBECOF_00401 7e-275 lpdA 1.8.1.4 C Dehydrogenase
NCMBECOF_00402 2.1e-228 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NCMBECOF_00403 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NCMBECOF_00404 8.8e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NCMBECOF_00405 1.3e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NCMBECOF_00406 8.8e-81
NCMBECOF_00407 9.8e-32 ykzG S Belongs to the UPF0356 family
NCMBECOF_00408 2.1e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NCMBECOF_00409 5.7e-29
NCMBECOF_00410 3.3e-85 L PFAM transposase IS200-family protein
NCMBECOF_00411 2.8e-138 mltD CBM50 M NlpC P60 family protein
NCMBECOF_00412 5.7e-135 L PFAM transposase, IS4 family protein
NCMBECOF_00413 2.2e-105 L PFAM transposase, IS4 family protein
NCMBECOF_00415 6.5e-57
NCMBECOF_00416 5e-120 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NCMBECOF_00417 1.2e-64 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NCMBECOF_00418 2e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NCMBECOF_00419 1.2e-219 patA 2.6.1.1 E Aminotransferase
NCMBECOF_00420 9.5e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NCMBECOF_00421 8.5e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NCMBECOF_00422 1.5e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NCMBECOF_00423 1.3e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NCMBECOF_00424 5e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NCMBECOF_00425 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NCMBECOF_00426 1.2e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NCMBECOF_00427 8.1e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NCMBECOF_00428 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NCMBECOF_00429 9e-119 S Repeat protein
NCMBECOF_00430 3.7e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NCMBECOF_00431 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NCMBECOF_00432 8.2e-57 XK27_04120 S Putative amino acid metabolism
NCMBECOF_00433 2.7e-216 iscS 2.8.1.7 E Aminotransferase class V
NCMBECOF_00434 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NCMBECOF_00436 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NCMBECOF_00437 4.7e-31 cspA K Cold shock protein
NCMBECOF_00438 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NCMBECOF_00439 1.9e-42 divIVA D DivIVA domain protein
NCMBECOF_00440 1.3e-145 ylmH S S4 domain protein
NCMBECOF_00441 8.3e-41 yggT S YGGT family
NCMBECOF_00442 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NCMBECOF_00443 3.4e-225 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NCMBECOF_00444 2.9e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NCMBECOF_00445 1.1e-142 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NCMBECOF_00446 7.3e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NCMBECOF_00447 3.8e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NCMBECOF_00448 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NCMBECOF_00449 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NCMBECOF_00450 2.6e-56 ftsL D Cell division protein FtsL
NCMBECOF_00451 6.1e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NCMBECOF_00452 1.2e-76 mraZ K Belongs to the MraZ family
NCMBECOF_00453 1.7e-57
NCMBECOF_00454 1.2e-10 S Protein of unknown function (DUF4044)
NCMBECOF_00455 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NCMBECOF_00456 4.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NCMBECOF_00457 2.9e-159 rrmA 2.1.1.187 H Methyltransferase
NCMBECOF_00458 7.8e-183 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NCMBECOF_00459 4.2e-21 L hmm pf00665
NCMBECOF_00461 6.1e-57
NCMBECOF_00464 1.4e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NCMBECOF_00465 6e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NCMBECOF_00466 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
NCMBECOF_00467 4.7e-114 yjbH Q Thioredoxin
NCMBECOF_00468 1.8e-264 pipD E Dipeptidase
NCMBECOF_00469 4.4e-202 coiA 3.6.4.12 S Competence protein
NCMBECOF_00470 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NCMBECOF_00471 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NCMBECOF_00472 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NCMBECOF_00474 2.7e-66 XK27_01125 L PFAM IS66 Orf2 family protein
NCMBECOF_00475 5.1e-295 L Transposase IS66 family
NCMBECOF_00495 6.1e-57
NCMBECOF_00498 5.5e-110 dedA S SNARE-like domain protein
NCMBECOF_00499 9.5e-102 S Protein of unknown function (DUF1461)
NCMBECOF_00500 1.9e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NCMBECOF_00501 6.6e-93 yutD S Protein of unknown function (DUF1027)
NCMBECOF_00502 4.7e-111 S Calcineurin-like phosphoesterase
NCMBECOF_00503 2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NCMBECOF_00504 4.5e-146 ytxK 2.1.1.72 L N-6 DNA Methylase
NCMBECOF_00506 1.8e-72
NCMBECOF_00507 2e-43
NCMBECOF_00508 2.9e-78 NU general secretion pathway protein
NCMBECOF_00509 2.7e-46 comGC U competence protein ComGC
NCMBECOF_00510 9.5e-189 comGB NU type II secretion system
NCMBECOF_00511 2.3e-184 comGA NU Type II IV secretion system protein
NCMBECOF_00512 5.4e-264 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_00513 1.6e-132 yebC K Transcriptional regulatory protein
NCMBECOF_00514 1.7e-135
NCMBECOF_00515 4.5e-183 ccpA K catabolite control protein A
NCMBECOF_00516 7.7e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NCMBECOF_00517 1.5e-29
NCMBECOF_00518 2.5e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NCMBECOF_00519 6.9e-148 ykuT M mechanosensitive ion channel
NCMBECOF_00520 1.5e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NCMBECOF_00521 3.3e-74 ykuL S (CBS) domain
NCMBECOF_00522 2.9e-93 S Phosphoesterase
NCMBECOF_00523 5.5e-101 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NCMBECOF_00524 6.5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NCMBECOF_00525 4.6e-97 yslB S Protein of unknown function (DUF2507)
NCMBECOF_00526 6.1e-54 trxA O Belongs to the thioredoxin family
NCMBECOF_00527 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NCMBECOF_00528 1.6e-86 cvpA S Colicin V production protein
NCMBECOF_00529 1.8e-47 yrzB S Belongs to the UPF0473 family
NCMBECOF_00530 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NCMBECOF_00531 4.1e-43 yrzL S Belongs to the UPF0297 family
NCMBECOF_00532 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NCMBECOF_00533 1.1e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NCMBECOF_00534 8e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NCMBECOF_00535 1.4e-30 yajC U Preprotein translocase
NCMBECOF_00536 5.4e-190 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NCMBECOF_00537 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NCMBECOF_00538 1.8e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NCMBECOF_00539 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NCMBECOF_00540 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NCMBECOF_00541 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
NCMBECOF_00542 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NCMBECOF_00543 1.7e-229 cinA 3.5.1.42 S Belongs to the CinA family
NCMBECOF_00544 7.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NCMBECOF_00545 6.9e-139 ymfM S Helix-turn-helix domain
NCMBECOF_00546 3e-248 ymfH S Peptidase M16
NCMBECOF_00547 2.3e-229 ymfF S Peptidase M16 inactive domain protein
NCMBECOF_00548 1.9e-158 aatB ET ABC transporter substrate-binding protein
NCMBECOF_00549 7.2e-118 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NCMBECOF_00550 2.1e-101 glnP P ABC transporter permease
NCMBECOF_00551 8.7e-93 mreD M rod shape-determining protein MreD
NCMBECOF_00552 2.6e-152 mreC M Involved in formation and maintenance of cell shape
NCMBECOF_00553 1.7e-179 mreB D cell shape determining protein MreB
NCMBECOF_00554 2e-120 radC L DNA repair protein
NCMBECOF_00555 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NCMBECOF_00556 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
NCMBECOF_00557 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NCMBECOF_00558 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NCMBECOF_00559 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NCMBECOF_00560 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
NCMBECOF_00561 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NCMBECOF_00562 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NCMBECOF_00563 3.5e-216 iscS2 2.8.1.7 E Aminotransferase class V
NCMBECOF_00564 6.7e-240 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NCMBECOF_00565 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NCMBECOF_00566 2.3e-187 gadC E amino acid
NCMBECOF_00567 1.4e-189 L PFAM Integrase catalytic region
NCMBECOF_00568 1.3e-58 gadC E amino acid
NCMBECOF_00569 3e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
NCMBECOF_00570 1.1e-286 gadC E amino acid
NCMBECOF_00571 3.4e-282 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NCMBECOF_00572 2.5e-237 pbuG S permease
NCMBECOF_00573 2.9e-259 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NCMBECOF_00574 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NCMBECOF_00575 1.4e-141 S Belongs to the UPF0246 family
NCMBECOF_00576 2.5e-138 S Membrane
NCMBECOF_00577 2.8e-75 4.4.1.5 E Glyoxalase
NCMBECOF_00578 1.5e-21
NCMBECOF_00579 2.2e-87 yueI S Protein of unknown function (DUF1694)
NCMBECOF_00580 4.5e-236 rarA L recombination factor protein RarA
NCMBECOF_00581 4.4e-46
NCMBECOF_00582 4.3e-83 usp6 T universal stress protein
NCMBECOF_00583 4.1e-206 araR K Transcriptional regulator
NCMBECOF_00584 2.4e-158 ytbE 1.1.1.346 S Aldo keto reductase
NCMBECOF_00585 2.4e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
NCMBECOF_00586 4.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NCMBECOF_00587 3.7e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NCMBECOF_00588 0.0 araB 2.7.1.16 G carbohydrate kinase FGGY
NCMBECOF_00589 1.2e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NCMBECOF_00590 1.6e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NCMBECOF_00591 4.8e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NCMBECOF_00592 3e-47 gcvH E glycine cleavage
NCMBECOF_00593 1.1e-220 rodA D Belongs to the SEDS family
NCMBECOF_00594 1e-31 S Protein of unknown function (DUF2969)
NCMBECOF_00595 1.9e-178 mbl D Cell shape determining protein MreB Mrl
NCMBECOF_00596 1.9e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NCMBECOF_00597 2.2e-33 ywzB S Protein of unknown function (DUF1146)
NCMBECOF_00598 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NCMBECOF_00599 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NCMBECOF_00600 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NCMBECOF_00601 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NCMBECOF_00602 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NCMBECOF_00603 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NCMBECOF_00604 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NCMBECOF_00605 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
NCMBECOF_00606 9.4e-231 pyrP F Permease
NCMBECOF_00607 2e-130 yibF S overlaps another CDS with the same product name
NCMBECOF_00608 1.5e-192 yibE S overlaps another CDS with the same product name
NCMBECOF_00609 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NCMBECOF_00610 8.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NCMBECOF_00611 5.8e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NCMBECOF_00612 7.2e-197 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NCMBECOF_00613 5.9e-168 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NCMBECOF_00614 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NCMBECOF_00615 4.6e-108 tdk 2.7.1.21 F thymidine kinase
NCMBECOF_00616 2e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
NCMBECOF_00617 1.4e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NCMBECOF_00619 1.5e-224 arcD U Amino acid permease
NCMBECOF_00620 5.2e-262 E Arginine ornithine antiporter
NCMBECOF_00621 2.7e-79 argR K Regulates arginine biosynthesis genes
NCMBECOF_00622 4.1e-239 arcA 3.5.3.6 E Arginine
NCMBECOF_00623 5.5e-197 ampC V Beta-lactamase
NCMBECOF_00624 1.2e-21
NCMBECOF_00625 0.0 M domain protein
NCMBECOF_00626 1.2e-88
NCMBECOF_00627 1.2e-133 L Belongs to the 'phage' integrase family
NCMBECOF_00628 3.1e-23 K Cro/C1-type HTH DNA-binding domain
NCMBECOF_00629 1.6e-17 S Helix-turn-helix domain
NCMBECOF_00630 6.2e-42 S Phage regulatory protein Rha (Phage_pRha)
NCMBECOF_00633 1.1e-07
NCMBECOF_00637 1.5e-08 L DnaD domain protein
NCMBECOF_00639 2.5e-68
NCMBECOF_00644 2.4e-29 yjcE P Sodium proton antiporter
NCMBECOF_00646 3.6e-57
NCMBECOF_00648 4.1e-86
NCMBECOF_00649 0.0 copA 3.6.3.54 P P-type ATPase
NCMBECOF_00650 2.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NCMBECOF_00651 7.9e-45 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NCMBECOF_00652 1.3e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NCMBECOF_00653 3.6e-163 EG EamA-like transporter family
NCMBECOF_00654 1.5e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NCMBECOF_00655 3.8e-190 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NCMBECOF_00656 9.5e-155 KT YcbB domain
NCMBECOF_00658 3.5e-26
NCMBECOF_00659 7.7e-263 pgi 5.3.1.9 G Belongs to the GPI family
NCMBECOF_00660 1.9e-99 lacA 2.3.1.79 S Transferase hexapeptide repeat
NCMBECOF_00661 4.8e-154 glcU U sugar transport
NCMBECOF_00662 6.4e-271 yclK 2.7.13.3 T Histidine kinase
NCMBECOF_00663 1.2e-134 K response regulator
NCMBECOF_00665 1.8e-78 lytE M Lysin motif
NCMBECOF_00666 3.6e-143 XK27_02985 S Cof-like hydrolase
NCMBECOF_00667 1e-78 K Transcriptional regulator
NCMBECOF_00668 0.0 oatA I Acyltransferase
NCMBECOF_00669 5.6e-52
NCMBECOF_00670 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NCMBECOF_00671 1.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NCMBECOF_00672 3.2e-124 ybbR S YbbR-like protein
NCMBECOF_00673 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NCMBECOF_00674 3.7e-249 fucP G Major Facilitator Superfamily
NCMBECOF_00675 1.3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NCMBECOF_00676 5e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCMBECOF_00677 1.3e-165 murB 1.3.1.98 M Cell wall formation
NCMBECOF_00678 5.1e-101 dnaQ 2.7.7.7 L DNA polymerase III
NCMBECOF_00679 8.9e-77 S PAS domain
NCMBECOF_00680 5.7e-86 K Acetyltransferase (GNAT) domain
NCMBECOF_00681 8.5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NCMBECOF_00682 4.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NCMBECOF_00683 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NCMBECOF_00684 6.3e-105 yxjI
NCMBECOF_00685 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NCMBECOF_00686 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NCMBECOF_00687 7.5e-146 est 3.1.1.1 S Serine aminopeptidase, S33
NCMBECOF_00688 1.8e-34 secG U Preprotein translocase
NCMBECOF_00689 5.8e-291 clcA P chloride
NCMBECOF_00690 5.6e-245 yifK E Amino acid permease
NCMBECOF_00691 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NCMBECOF_00692 2.4e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NCMBECOF_00693 9.3e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NCMBECOF_00694 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NCMBECOF_00696 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NCMBECOF_00697 9.7e-242 glpT G Major Facilitator Superfamily
NCMBECOF_00698 8.8e-15
NCMBECOF_00700 4e-170 whiA K May be required for sporulation
NCMBECOF_00701 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NCMBECOF_00702 9.2e-161 rapZ S Displays ATPase and GTPase activities
NCMBECOF_00703 1.7e-235 steT E amino acid
NCMBECOF_00704 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NCMBECOF_00705 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NCMBECOF_00706 6.9e-14
NCMBECOF_00707 1.9e-115 yfbR S HD containing hydrolase-like enzyme
NCMBECOF_00708 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NCMBECOF_00709 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
NCMBECOF_00710 1.9e-161 aatB ET PFAM extracellular solute-binding protein, family 3
NCMBECOF_00711 5.3e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NCMBECOF_00712 1.7e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NCMBECOF_00713 3.5e-168 lutA C Cysteine-rich domain
NCMBECOF_00714 6e-293 lutB C 4Fe-4S dicluster domain
NCMBECOF_00715 2.5e-135 yrjD S LUD domain
NCMBECOF_00716 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NCMBECOF_00717 3.8e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NCMBECOF_00718 1.4e-153 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NCMBECOF_00719 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NCMBECOF_00720 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NCMBECOF_00721 3.1e-32 KT PspC domain protein
NCMBECOF_00722 2.3e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NCMBECOF_00723 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NCMBECOF_00724 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NCMBECOF_00725 1.6e-120 comFC S Competence protein
NCMBECOF_00726 4.9e-254 comFA L Helicase C-terminal domain protein
NCMBECOF_00727 9.2e-110 yvyE 3.4.13.9 S YigZ family
NCMBECOF_00728 2.8e-62 EGP Major facilitator Superfamily
NCMBECOF_00729 6.9e-48 EGP Major facilitator Superfamily
NCMBECOF_00730 1.4e-189 L PFAM Integrase catalytic region
NCMBECOF_00731 5.3e-82 yaaU EGP Major facilitator Superfamily
NCMBECOF_00732 6.2e-67 rmaI K Transcriptional regulator
NCMBECOF_00733 2.7e-39
NCMBECOF_00734 0.0 ydaO E amino acid
NCMBECOF_00735 4.8e-304 ybeC E amino acid
NCMBECOF_00736 5.3e-81 S Aminoacyl-tRNA editing domain
NCMBECOF_00737 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NCMBECOF_00738 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NCMBECOF_00739 1.2e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NCMBECOF_00740 6.5e-300 uup S ABC transporter, ATP-binding protein
NCMBECOF_00741 1.1e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NCMBECOF_00742 3.1e-228 mtnE 2.6.1.83 E Aminotransferase
NCMBECOF_00743 1.1e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NCMBECOF_00744 2.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NCMBECOF_00745 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NCMBECOF_00746 4e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NCMBECOF_00747 8e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NCMBECOF_00748 7.3e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NCMBECOF_00749 1.8e-125 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NCMBECOF_00750 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NCMBECOF_00751 1.8e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NCMBECOF_00752 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NCMBECOF_00753 5.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NCMBECOF_00754 5.6e-138 fat 3.1.2.21 I Acyl-ACP thioesterase
NCMBECOF_00755 8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NCMBECOF_00756 1.6e-58 yabA L Involved in initiation control of chromosome replication
NCMBECOF_00757 4.3e-186 holB 2.7.7.7 L DNA polymerase III
NCMBECOF_00758 7.6e-52 yaaQ S Cyclic-di-AMP receptor
NCMBECOF_00759 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NCMBECOF_00760 9.7e-39 S Protein of unknown function (DUF2508)
NCMBECOF_00761 4.8e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NCMBECOF_00762 4.6e-46 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NCMBECOF_00763 3.6e-308 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NCMBECOF_00764 2.5e-250 L PFAM transposase, IS4 family protein
NCMBECOF_00765 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NCMBECOF_00766 3.4e-35 nrdH O Glutaredoxin
NCMBECOF_00767 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NCMBECOF_00768 1.2e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NCMBECOF_00769 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NCMBECOF_00770 2.4e-125 S Putative adhesin
NCMBECOF_00771 5.1e-81 XK27_06920 S Protein of unknown function (DUF1700)
NCMBECOF_00772 1.1e-56 K transcriptional regulator PadR family
NCMBECOF_00773 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NCMBECOF_00774 3.3e-85 L PFAM transposase IS200-family protein
NCMBECOF_00776 7.7e-48
NCMBECOF_00777 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NCMBECOF_00778 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NCMBECOF_00779 1.4e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NCMBECOF_00780 1.1e-242 M Glycosyl transferase family group 2
NCMBECOF_00782 2e-227 aadAT EK Aminotransferase, class I
NCMBECOF_00783 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NCMBECOF_00784 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NCMBECOF_00785 1.1e-95 nusG K Participates in transcription elongation, termination and antitermination
NCMBECOF_00786 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NCMBECOF_00787 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NCMBECOF_00788 5.7e-135 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NCMBECOF_00789 7.2e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NCMBECOF_00790 1.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NCMBECOF_00791 1.9e-206 yacL S domain protein
NCMBECOF_00792 1.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NCMBECOF_00793 1.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NCMBECOF_00794 1.6e-48 HA62_12640 S GCN5-related N-acetyl-transferase
NCMBECOF_00795 1.3e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NCMBECOF_00796 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
NCMBECOF_00797 4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NCMBECOF_00798 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NCMBECOF_00799 3.2e-119 tcyB E ABC transporter
NCMBECOF_00800 7.7e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NCMBECOF_00801 7e-169 I alpha/beta hydrolase fold
NCMBECOF_00802 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NCMBECOF_00803 0.0 S Bacterial membrane protein, YfhO
NCMBECOF_00804 1.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NCMBECOF_00805 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NCMBECOF_00807 6.8e-83 ydcK S Belongs to the SprT family
NCMBECOF_00808 0.0 yhgF K Tex-like protein N-terminal domain protein
NCMBECOF_00809 2.8e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NCMBECOF_00810 4.5e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NCMBECOF_00811 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
NCMBECOF_00812 2.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NCMBECOF_00813 3.5e-302 aspT P Predicted Permease Membrane Region
NCMBECOF_00814 5.9e-250 EGP Major facilitator Superfamily
NCMBECOF_00815 1.4e-108
NCMBECOF_00818 1.9e-95 yjjH S Calcineurin-like phosphoesterase
NCMBECOF_00819 1.2e-11 yjjH S Calcineurin-like phosphoesterase
NCMBECOF_00820 8.5e-263 dtpT U amino acid peptide transporter
NCMBECOF_00821 8.3e-19
NCMBECOF_00822 1.4e-189 L PFAM Integrase catalytic region
NCMBECOF_00824 9.4e-13 K Cro/C1-type HTH DNA-binding domain
NCMBECOF_00825 3.5e-296 L Transposase IS66 family
NCMBECOF_00826 2.7e-66 XK27_01125 L PFAM IS66 Orf2 family protein
NCMBECOF_00830 6.1e-57
NCMBECOF_00831 9.4e-280 O Arylsulfotransferase (ASST)
NCMBECOF_00832 4.7e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NCMBECOF_00833 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NCMBECOF_00834 1.1e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NCMBECOF_00835 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NCMBECOF_00836 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NCMBECOF_00837 9.9e-258 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NCMBECOF_00838 9.8e-67 yabR J RNA binding
NCMBECOF_00839 2.3e-57 divIC D Septum formation initiator
NCMBECOF_00840 2.1e-39 yabO J S4 domain protein
NCMBECOF_00841 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NCMBECOF_00842 9.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NCMBECOF_00843 3.6e-114 S (CBS) domain
NCMBECOF_00844 1.9e-144 tesE Q hydratase
NCMBECOF_00845 1.2e-241 codA 3.5.4.1 F cytosine deaminase
NCMBECOF_00846 7.5e-250 U Belongs to the purine-cytosine permease (2.A.39) family
NCMBECOF_00847 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
NCMBECOF_00848 1.1e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NCMBECOF_00849 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NCMBECOF_00851 7.2e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NCMBECOF_00852 1e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
NCMBECOF_00853 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NCMBECOF_00854 3.4e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NCMBECOF_00855 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NCMBECOF_00856 0.0 sprD D Domain of Unknown Function (DUF1542)
NCMBECOF_00857 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NCMBECOF_00858 2.6e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NCMBECOF_00859 1.5e-158 htpX O Belongs to the peptidase M48B family
NCMBECOF_00860 7e-93 lemA S LemA family
NCMBECOF_00861 1.8e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCMBECOF_00862 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
NCMBECOF_00863 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NCMBECOF_00864 2.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NCMBECOF_00865 7.9e-159 3.2.1.55 GH51 G Right handed beta helix region
NCMBECOF_00866 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NCMBECOF_00867 8.6e-125 srtA 3.4.22.70 M sortase family
NCMBECOF_00868 3e-167 S Alpha/beta hydrolase of unknown function (DUF915)
NCMBECOF_00869 6.1e-241 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NCMBECOF_00870 4.6e-41 rpmE2 J Ribosomal protein L31
NCMBECOF_00871 8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NCMBECOF_00872 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NCMBECOF_00873 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NCMBECOF_00874 1.2e-67 ywiB S Domain of unknown function (DUF1934)
NCMBECOF_00875 4.6e-154 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
NCMBECOF_00876 3.8e-270 ywfO S HD domain protein
NCMBECOF_00877 1e-145 yxeH S hydrolase
NCMBECOF_00878 2.3e-48
NCMBECOF_00879 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NCMBECOF_00880 4.1e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NCMBECOF_00881 1.5e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NCMBECOF_00882 7.2e-128 znuB U ABC 3 transport family
NCMBECOF_00883 1.3e-122 fhuC P ABC transporter
NCMBECOF_00884 1.1e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
NCMBECOF_00885 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NCMBECOF_00886 6.8e-37 veg S Biofilm formation stimulator VEG
NCMBECOF_00887 2.1e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NCMBECOF_00888 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NCMBECOF_00889 3.5e-154 tatD L hydrolase, TatD family
NCMBECOF_00890 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NCMBECOF_00891 2.1e-160 yunF F Protein of unknown function DUF72
NCMBECOF_00893 8.8e-130 cobB K SIR2 family
NCMBECOF_00894 2.7e-177
NCMBECOF_00895 7.7e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NCMBECOF_00896 1.2e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NCMBECOF_00897 4.5e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NCMBECOF_00898 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NCMBECOF_00899 4.9e-295 L Transposase
NCMBECOF_00900 0.0 helD 3.6.4.12 L DNA helicase
NCMBECOF_00901 2.4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NCMBECOF_00903 1.7e-254 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NCMBECOF_00904 2.8e-266 yfnA E amino acid
NCMBECOF_00905 5.4e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NCMBECOF_00906 8.6e-44 1.3.5.4 S FMN binding
NCMBECOF_00907 2.9e-221 norA EGP Major facilitator Superfamily
NCMBECOF_00908 2.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NCMBECOF_00909 2.5e-155 metQ1 P Belongs to the nlpA lipoprotein family
NCMBECOF_00910 2.8e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NCMBECOF_00911 3.4e-102 metI P ABC transporter permease
NCMBECOF_00912 1.3e-215 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NCMBECOF_00913 5.4e-253 clcA P chloride
NCMBECOF_00914 1.8e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NCMBECOF_00915 2.5e-99 proW P ABC transporter, permease protein
NCMBECOF_00916 1.4e-141 proV E ABC transporter, ATP-binding protein
NCMBECOF_00917 1.8e-108 proWZ P ABC transporter permease
NCMBECOF_00918 1.5e-161 proX M ABC transporter, substrate-binding protein, QAT family
NCMBECOF_00919 2.1e-76 K Transcriptional regulator
NCMBECOF_00920 2.2e-154 1.6.5.2 GM NAD(P)H-binding
NCMBECOF_00922 1.8e-215 5.4.2.7 G Metalloenzyme superfamily
NCMBECOF_00923 3e-310 cadA P P-type ATPase
NCMBECOF_00924 6.4e-131 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NCMBECOF_00925 5.6e-124
NCMBECOF_00926 1.8e-53 S Sugar efflux transporter for intercellular exchange
NCMBECOF_00927 3.4e-247 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NCMBECOF_00929 0.0 L Helicase C-terminal domain protein
NCMBECOF_00930 5.8e-75 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
NCMBECOF_00931 1.7e-179 S Aldo keto reductase
NCMBECOF_00933 4.2e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NCMBECOF_00934 4.5e-62 psiE S Phosphate-starvation-inducible E
NCMBECOF_00935 3.1e-98 ydeN S Serine hydrolase
NCMBECOF_00937 1.6e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NCMBECOF_00938 3.6e-30 nhaC C Na H antiporter NhaC
NCMBECOF_00939 4.5e-214 nhaC C Na H antiporter NhaC
NCMBECOF_00940 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
NCMBECOF_00941 2.8e-114 ywnB S NAD(P)H-binding
NCMBECOF_00942 3.7e-37
NCMBECOF_00943 2.1e-129 IQ Dehydrogenase reductase
NCMBECOF_00944 1.6e-241 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
NCMBECOF_00945 1.4e-43 hxlR K Transcriptional regulator, HxlR family
NCMBECOF_00946 5.7e-162 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NCMBECOF_00947 7.3e-10
NCMBECOF_00949 6.1e-57
NCMBECOF_00950 8.4e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NCMBECOF_00951 1e-174
NCMBECOF_00952 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NCMBECOF_00953 2.8e-243 purD 6.3.4.13 F Belongs to the GARS family
NCMBECOF_00954 1.7e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NCMBECOF_00955 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NCMBECOF_00956 8.1e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NCMBECOF_00957 5e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NCMBECOF_00958 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NCMBECOF_00959 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NCMBECOF_00960 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NCMBECOF_00961 4.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NCMBECOF_00962 4e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NCMBECOF_00963 2.1e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NCMBECOF_00964 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NCMBECOF_00965 3.7e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NCMBECOF_00966 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NCMBECOF_00967 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NCMBECOF_00968 5.6e-173 K AI-2E family transporter
NCMBECOF_00969 7.4e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NCMBECOF_00970 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NCMBECOF_00971 3e-116 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
NCMBECOF_00972 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NCMBECOF_00973 4.6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NCMBECOF_00974 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NCMBECOF_00975 3.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NCMBECOF_00976 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NCMBECOF_00977 1.3e-133 K LysR substrate binding domain
NCMBECOF_00978 3.6e-52 azlD S branched-chain amino acid
NCMBECOF_00979 9.4e-140 azlC E AzlC protein
NCMBECOF_00980 7.8e-200 hpk31 2.7.13.3 T Histidine kinase
NCMBECOF_00981 3.8e-125 K response regulator
NCMBECOF_00982 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NCMBECOF_00983 1.1e-172 deoR K sugar-binding domain protein
NCMBECOF_00984 6.9e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NCMBECOF_00985 2.9e-235 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
NCMBECOF_00986 4.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NCMBECOF_00987 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NCMBECOF_00988 4.2e-133 XK27_01040 S Protein of unknown function (DUF1129)
NCMBECOF_00989 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NCMBECOF_00990 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
NCMBECOF_00991 1.6e-152 spo0J K Belongs to the ParB family
NCMBECOF_00992 1.4e-139 soj D Sporulation initiation inhibitor
NCMBECOF_00993 1.1e-149 noc K Belongs to the ParB family
NCMBECOF_00994 2.3e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NCMBECOF_00995 2.2e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NCMBECOF_00996 6e-171 rihC 3.2.2.1 F Nucleoside
NCMBECOF_00997 1e-218 nupG F Nucleoside transporter
NCMBECOF_00998 1.2e-220 cycA E Amino acid permease
NCMBECOF_00999 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NCMBECOF_01000 4e-265 glnP P ABC transporter
NCMBECOF_01001 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NCMBECOF_01002 0.0 UW LPXTG-motif cell wall anchor domain protein
NCMBECOF_01003 2.5e-266 fhaB M Rib/alpha-like repeat
NCMBECOF_01004 3e-178 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NCMBECOF_01005 4.7e-198 XK27_09615 S reductase
NCMBECOF_01006 4.6e-100 nqr 1.5.1.36 S reductase
NCMBECOF_01007 1.6e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NCMBECOF_01008 4.8e-177 K Transcriptional regulator, LacI family
NCMBECOF_01009 1.6e-260 G Major Facilitator
NCMBECOF_01010 6.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NCMBECOF_01011 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NCMBECOF_01012 1.4e-267 G Major Facilitator
NCMBECOF_01013 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NCMBECOF_01014 6e-54 M domain protein
NCMBECOF_01015 1.1e-211 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
NCMBECOF_01016 8.8e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NCMBECOF_01017 1.1e-270 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NCMBECOF_01018 2.2e-72
NCMBECOF_01019 6.9e-113 K Transcriptional regulator, TetR family
NCMBECOF_01021 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NCMBECOF_01022 5.1e-78
NCMBECOF_01023 9e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NCMBECOF_01024 3.8e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NCMBECOF_01025 4.6e-260 nox C NADH oxidase
NCMBECOF_01026 8.6e-87 hmpT S ECF-type riboflavin transporter, S component
NCMBECOF_01027 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NCMBECOF_01028 2.2e-105 L PFAM transposase, IS4 family protein
NCMBECOF_01029 5.7e-135 L PFAM transposase, IS4 family protein
NCMBECOF_01030 3.3e-166 yvgN C Aldo keto reductase
NCMBECOF_01031 1.1e-135 puuD S peptidase C26
NCMBECOF_01032 1.4e-256 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NCMBECOF_01033 3.5e-127 yfeO P Voltage gated chloride channel
NCMBECOF_01034 1.7e-66 yfeO P Voltage gated chloride channel
NCMBECOF_01035 4e-218 sptS 2.7.13.3 T Histidine kinase
NCMBECOF_01036 4.5e-115 K response regulator
NCMBECOF_01037 9e-86 2.7.6.5 T Region found in RelA / SpoT proteins
NCMBECOF_01038 1.7e-71
NCMBECOF_01039 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NCMBECOF_01040 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NCMBECOF_01041 6.9e-256 malT G Major Facilitator
NCMBECOF_01042 1.2e-211 phbA 2.3.1.9 I Belongs to the thiolase family
NCMBECOF_01043 4.7e-171 malR K Transcriptional regulator, LacI family
NCMBECOF_01044 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NCMBECOF_01045 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NCMBECOF_01046 1.4e-50 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01047 2.9e-201 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01048 1.2e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NCMBECOF_01049 6.3e-105 wecD3 K PFAM GCN5-related N-acetyltransferase
NCMBECOF_01051 5.9e-205 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NCMBECOF_01052 0.0 clpL O associated with various cellular activities
NCMBECOF_01053 1.3e-31
NCMBECOF_01054 9.5e-217 patA 2.6.1.1 E Aminotransferase
NCMBECOF_01055 9.8e-175 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCMBECOF_01056 8.5e-75 osmC O OsmC-like protein
NCMBECOF_01058 1.3e-240 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NCMBECOF_01062 5.1e-262 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01063 2.9e-134 K LytTr DNA-binding domain
NCMBECOF_01064 7.1e-189 2.7.13.3 T GHKL domain
NCMBECOF_01067 1.8e-167 S Putative peptidoglycan binding domain
NCMBECOF_01068 1.4e-189 L PFAM Integrase catalytic region
NCMBECOF_01069 2.7e-40 S Putative peptidoglycan binding domain
NCMBECOF_01070 1.7e-29
NCMBECOF_01071 5.6e-212 bacI V MacB-like periplasmic core domain
NCMBECOF_01072 6.3e-128 V ABC transporter
NCMBECOF_01073 1.1e-142 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NCMBECOF_01074 6.1e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NCMBECOF_01075 1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NCMBECOF_01076 2.7e-148 E Glyoxalase-like domain
NCMBECOF_01077 1e-119 glcU U sugar transport
NCMBECOF_01078 2.5e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NCMBECOF_01079 1.1e-95 S reductase
NCMBECOF_01081 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NCMBECOF_01082 2.1e-177 ABC-SBP S ABC transporter
NCMBECOF_01083 5.9e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NCMBECOF_01084 3.5e-217 htrA 3.4.21.107 O serine protease
NCMBECOF_01085 2.3e-153 vicX 3.1.26.11 S domain protein
NCMBECOF_01086 2.4e-150 yycI S YycH protein
NCMBECOF_01087 2.1e-249 yycH S YycH protein
NCMBECOF_01088 0.0 vicK 2.7.13.3 T Histidine kinase
NCMBECOF_01089 3.1e-130 K response regulator
NCMBECOF_01091 1.2e-308 lmrA 3.6.3.44 V ABC transporter
NCMBECOF_01092 1.2e-73 K helix_turn_helix multiple antibiotic resistance protein
NCMBECOF_01094 9.9e-100 K DNA-binding helix-turn-helix protein
NCMBECOF_01095 2.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
NCMBECOF_01096 8.5e-59
NCMBECOF_01097 4.5e-206 yttB EGP Major facilitator Superfamily
NCMBECOF_01098 5.3e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NCMBECOF_01099 2e-74 rplI J Binds to the 23S rRNA
NCMBECOF_01100 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NCMBECOF_01101 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NCMBECOF_01102 3.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NCMBECOF_01103 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NCMBECOF_01104 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NCMBECOF_01105 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NCMBECOF_01106 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NCMBECOF_01107 1.7e-34 yaaA S S4 domain protein YaaA
NCMBECOF_01108 2.2e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NCMBECOF_01109 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NCMBECOF_01110 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NCMBECOF_01111 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NCMBECOF_01112 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NCMBECOF_01113 2.9e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
NCMBECOF_01114 6.5e-213 hsdM 2.1.1.72 V type I restriction-modification system
NCMBECOF_01115 1.5e-53 3.1.21.3 V Type I restriction
NCMBECOF_01116 1.8e-133 L Belongs to the 'phage' integrase family
NCMBECOF_01117 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NCMBECOF_01119 6.3e-37 3.1.21.3 V Type I restriction modification DNA specificity domain
NCMBECOF_01122 1.9e-133 jag S R3H domain protein
NCMBECOF_01123 1.3e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NCMBECOF_01124 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NCMBECOF_01125 0.0 asnB 6.3.5.4 E Asparagine synthase
NCMBECOF_01126 5.6e-294 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NCMBECOF_01127 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
NCMBECOF_01128 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NCMBECOF_01129 1.4e-92 2.3.1.183 M Acetyltransferase GNAT family
NCMBECOF_01131 1.2e-165 S reductase
NCMBECOF_01132 5.3e-300 S amidohydrolase
NCMBECOF_01133 1.3e-40 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NCMBECOF_01134 1.3e-82 V ABC transporter, ATP-binding protein
NCMBECOF_01135 2.8e-17 CP ABC-2 family transporter protein
NCMBECOF_01137 1.2e-08
NCMBECOF_01138 4.2e-43 azlD E Branched-chain amino acid transport
NCMBECOF_01139 5.9e-112 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NCMBECOF_01141 2.7e-123 yhiD S MgtC family
NCMBECOF_01142 1.6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NCMBECOF_01143 2.3e-195 V Beta-lactamase
NCMBECOF_01144 4.5e-65 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCMBECOF_01145 6.5e-87 XK27_08850 J Aminoacyl-tRNA editing domain
NCMBECOF_01146 5.2e-19 relB L Addiction module antitoxin, RelB DinJ family
NCMBECOF_01147 1e-24
NCMBECOF_01148 5.1e-60 K LytTr DNA-binding domain
NCMBECOF_01149 3.8e-208 2.7.13.3 T GHKL domain
NCMBECOF_01153 8.7e-70 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
NCMBECOF_01154 9.1e-142 mleP3 S Membrane transport protein
NCMBECOF_01155 2.8e-120 T Transcriptional regulatory protein, C terminal
NCMBECOF_01156 9.6e-234 T GHKL domain
NCMBECOF_01157 3.7e-106 S Peptidase propeptide and YPEB domain
NCMBECOF_01158 3.3e-114 P nitric oxide dioxygenase activity
NCMBECOF_01159 9.9e-09 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
NCMBECOF_01160 8.6e-56 yphJ 4.1.1.44 S decarboxylase
NCMBECOF_01161 1.2e-12 S Oxidoreductase, aldo keto reductase family protein
NCMBECOF_01162 7.3e-83 C Flavodoxin
NCMBECOF_01163 1.3e-67 K Transcriptional regulator
NCMBECOF_01164 4.5e-82 lacA S transferase hexapeptide repeat
NCMBECOF_01165 1.7e-126 S Alpha beta hydrolase
NCMBECOF_01166 1.7e-153 tesE Q hydratase
NCMBECOF_01167 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NCMBECOF_01168 1.4e-228 aadAT EK Aminotransferase, class I
NCMBECOF_01169 1e-155 ypuA S Protein of unknown function (DUF1002)
NCMBECOF_01170 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
NCMBECOF_01171 6.4e-138 K Transcriptional regulator
NCMBECOF_01172 2.1e-160 akr5f 1.1.1.346 S reductase
NCMBECOF_01173 1.5e-103 K Transcriptional regulator C-terminal region
NCMBECOF_01174 1.1e-185 S membrane
NCMBECOF_01175 4.2e-110 GM NAD(P)H-binding
NCMBECOF_01176 8.2e-63 yneR
NCMBECOF_01177 2.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
NCMBECOF_01178 3.5e-138 T EAL domain
NCMBECOF_01179 1.6e-213 pgaC GT2 M Glycosyl transferase
NCMBECOF_01180 3.3e-86
NCMBECOF_01181 1.1e-198 2.7.7.65 T GGDEF domain
NCMBECOF_01182 2.2e-120 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NCMBECOF_01183 5.1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NCMBECOF_01184 2.4e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
NCMBECOF_01185 5.3e-93 folT S ECF transporter, substrate-specific component
NCMBECOF_01186 5.5e-48 K Transcriptional regulator
NCMBECOF_01187 0.0 pepN 3.4.11.2 E aminopeptidase
NCMBECOF_01188 5.8e-112 ylbE GM NAD dependent epimerase dehydratase family protein
NCMBECOF_01189 1e-256 pepC 3.4.22.40 E aminopeptidase
NCMBECOF_01191 5.7e-135 L PFAM transposase, IS4 family protein
NCMBECOF_01192 2.2e-105 L PFAM transposase, IS4 family protein
NCMBECOF_01193 5e-199 EGP Major facilitator Superfamily
NCMBECOF_01194 2.1e-233
NCMBECOF_01195 6.2e-84 K Transcriptional regulator, HxlR family
NCMBECOF_01196 3.3e-109 XK27_02070 S Nitroreductase family
NCMBECOF_01197 2.5e-52 hxlR K Transcriptional regulator, HxlR family
NCMBECOF_01198 1.7e-119 GM NmrA-like family
NCMBECOF_01199 2.5e-74 elaA S Gnat family
NCMBECOF_01200 2.4e-39 S Cytochrome B5
NCMBECOF_01201 5.4e-09 S Cytochrome B5
NCMBECOF_01202 1.6e-41 S Cytochrome B5
NCMBECOF_01203 8.8e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
NCMBECOF_01205 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NCMBECOF_01206 2.9e-241 E amino acid
NCMBECOF_01207 1.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
NCMBECOF_01208 8.1e-227 yxiO S Vacuole effluxer Atg22 like
NCMBECOF_01210 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NCMBECOF_01211 7.8e-30
NCMBECOF_01212 1e-290 mntH P H( )-stimulated, divalent metal cation uptake system
NCMBECOF_01213 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NCMBECOF_01214 4.4e-86 ygfC K transcriptional regulator (TetR family)
NCMBECOF_01215 8.9e-166 hrtB V ABC transporter permease
NCMBECOF_01216 3.2e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NCMBECOF_01217 0.0 yhcA V ABC transporter, ATP-binding protein
NCMBECOF_01218 5.6e-36
NCMBECOF_01219 4.1e-50 czrA K Transcriptional regulator, ArsR family
NCMBECOF_01220 2.3e-240 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NCMBECOF_01221 3.5e-174 scrR K Transcriptional regulator, LacI family
NCMBECOF_01222 1e-24
NCMBECOF_01223 4.1e-102
NCMBECOF_01224 2.1e-216 yttB EGP Major facilitator Superfamily
NCMBECOF_01225 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NCMBECOF_01226 3.3e-85 L PFAM transposase IS200-family protein
NCMBECOF_01227 3.1e-89
NCMBECOF_01228 4.2e-110 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NCMBECOF_01229 3.6e-260 S Putative peptidoglycan binding domain
NCMBECOF_01230 1.2e-123 yciB M ErfK YbiS YcfS YnhG
NCMBECOF_01232 6.7e-99
NCMBECOF_01233 9.7e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NCMBECOF_01234 1.2e-123 S Alpha beta hydrolase
NCMBECOF_01235 1.1e-261 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01236 8.4e-207 gldA 1.1.1.6 C dehydrogenase
NCMBECOF_01237 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NCMBECOF_01238 1.3e-41
NCMBECOF_01239 6.5e-127 pgm3 3.1.3.73 G phosphoglycerate mutase family
NCMBECOF_01240 7.6e-283 S C4-dicarboxylate anaerobic carrier
NCMBECOF_01241 1.2e-247 nhaC C Na H antiporter NhaC
NCMBECOF_01242 3.6e-241 pbuX F xanthine permease
NCMBECOF_01243 1.3e-281 pipD E Dipeptidase
NCMBECOF_01244 9.7e-169 corA P CorA-like Mg2+ transporter protein
NCMBECOF_01245 6.3e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NCMBECOF_01246 2.3e-131 terC P membrane
NCMBECOF_01247 1.2e-52 trxA O Belongs to the thioredoxin family
NCMBECOF_01248 2e-236 mepA V MATE efflux family protein
NCMBECOF_01250 1.1e-91 M domain protein
NCMBECOF_01251 8.9e-56 K Transcriptional regulator, ArsR family
NCMBECOF_01252 1.7e-94 P Cadmium resistance transporter
NCMBECOF_01253 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
NCMBECOF_01254 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NCMBECOF_01255 2.2e-182 ABC-SBP S ABC transporter
NCMBECOF_01256 5e-73 M PFAM NLP P60 protein
NCMBECOF_01257 1.8e-08
NCMBECOF_01258 2.5e-250 L PFAM transposase, IS4 family protein
NCMBECOF_01259 1.1e-67 S Protein of unknown function (DUF3278)
NCMBECOF_01260 6.7e-31 WQ51_00220 K Helix-turn-helix domain
NCMBECOF_01261 3.5e-24 K Helix-turn-helix domain
NCMBECOF_01262 2.8e-95 cadD P Cadmium resistance transporter
NCMBECOF_01263 4.2e-56 cadX K Bacterial regulatory protein, arsR family
NCMBECOF_01264 3.9e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NCMBECOF_01265 9.5e-181 arsB 1.20.4.1 P Sodium Bile acid symporter family
NCMBECOF_01266 2.4e-34 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
NCMBECOF_01267 2.7e-07 S HTH domain
NCMBECOF_01268 5.4e-273 S ABC transporter, ATP-binding protein
NCMBECOF_01269 2.9e-142 S Putative ABC-transporter type IV
NCMBECOF_01270 1.9e-104 NU mannosyl-glycoprotein
NCMBECOF_01271 2.7e-247 brnQ U Component of the transport system for branched-chain amino acids
NCMBECOF_01272 3.7e-232 S Uncharacterized protein conserved in bacteria (DUF2325)
NCMBECOF_01273 3.4e-205 nrnB S DHHA1 domain
NCMBECOF_01274 4.7e-08 nrnB S DHHA1 domain
NCMBECOF_01275 5.3e-49
NCMBECOF_01276 6.5e-134 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NCMBECOF_01277 3.3e-18 S Domain of unknown function (DUF4767)
NCMBECOF_01278 3.6e-54
NCMBECOF_01279 6e-123 yrkL S Flavodoxin-like fold
NCMBECOF_01281 1.4e-65 yeaO S Protein of unknown function, DUF488
NCMBECOF_01282 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NCMBECOF_01283 4e-204 3.1.3.1 S associated with various cellular activities
NCMBECOF_01284 1.2e-236 S Putative metallopeptidase domain
NCMBECOF_01285 3.6e-48
NCMBECOF_01286 0.0 pepO 3.4.24.71 O Peptidase family M13
NCMBECOF_01287 5.6e-107 K Helix-turn-helix domain
NCMBECOF_01288 3.2e-89 ymdB S Macro domain protein
NCMBECOF_01289 3.7e-197 EGP Major facilitator Superfamily
NCMBECOF_01290 6.4e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NCMBECOF_01291 6.7e-53 K helix_turn_helix, mercury resistance
NCMBECOF_01292 4.4e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NCMBECOF_01293 4.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NCMBECOF_01294 0.0 ysaB V FtsX-like permease family
NCMBECOF_01295 3.4e-135 macB2 V ABC transporter, ATP-binding protein
NCMBECOF_01296 1.3e-182 T PhoQ Sensor
NCMBECOF_01297 5.8e-126 K response regulator
NCMBECOF_01298 1.6e-157 ytbE 1.1.1.346 S Aldo keto reductase
NCMBECOF_01299 1.8e-136 pnuC H nicotinamide mononucleotide transporter
NCMBECOF_01300 2.9e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NCMBECOF_01301 6.6e-204
NCMBECOF_01302 1.8e-53
NCMBECOF_01303 9.1e-36
NCMBECOF_01304 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
NCMBECOF_01305 1.6e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
NCMBECOF_01306 5.8e-180 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NCMBECOF_01307 1e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NCMBECOF_01308 5.1e-281 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NCMBECOF_01309 2.7e-180 galR K Transcriptional regulator
NCMBECOF_01310 1.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
NCMBECOF_01311 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NCMBECOF_01312 1.3e-262 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01313 3.7e-79 K AsnC family
NCMBECOF_01314 1.4e-189 L PFAM Integrase catalytic region
NCMBECOF_01315 6.2e-79 uspA T universal stress protein
NCMBECOF_01316 0.0 lacS G Transporter
NCMBECOF_01317 2.7e-39
NCMBECOF_01318 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NCMBECOF_01319 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NCMBECOF_01320 3.1e-193 yeaN P Transporter, major facilitator family protein
NCMBECOF_01321 1.2e-73 S 3-demethylubiquinone-9 3-methyltransferase
NCMBECOF_01322 1.3e-84 nrdI F Belongs to the NrdI family
NCMBECOF_01323 2.3e-240 yhdP S Transporter associated domain
NCMBECOF_01324 4.9e-154 ypdB V (ABC) transporter
NCMBECOF_01325 7.2e-92 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
NCMBECOF_01326 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
NCMBECOF_01327 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
NCMBECOF_01328 1.6e-134 XK27_07210 6.1.1.6 S B3 4 domain
NCMBECOF_01329 3e-172 S AI-2E family transporter
NCMBECOF_01330 4.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NCMBECOF_01331 1.6e-163
NCMBECOF_01332 1.2e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NCMBECOF_01333 4.3e-147 eutJ E Hsp70 protein
NCMBECOF_01334 1.2e-177 K helix_turn_helix, arabinose operon control protein
NCMBECOF_01335 6.2e-42 pduA_4 CQ BMC
NCMBECOF_01336 2.7e-134 pduB E BMC
NCMBECOF_01337 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
NCMBECOF_01338 1.1e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
NCMBECOF_01339 1.1e-76 pduE 4.2.1.28 Q Dehydratase small subunit
NCMBECOF_01340 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
NCMBECOF_01341 2.9e-60 pduH S Dehydratase medium subunit
NCMBECOF_01342 8.4e-70 pduK CQ BMC
NCMBECOF_01343 7.6e-43 pduA_4 CQ BMC
NCMBECOF_01344 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
NCMBECOF_01345 6.4e-90 S Putative propanediol utilisation
NCMBECOF_01346 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
NCMBECOF_01347 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
NCMBECOF_01348 7.4e-80 pduO S Haem-degrading
NCMBECOF_01349 4e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
NCMBECOF_01350 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
NCMBECOF_01351 2.8e-210 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NCMBECOF_01352 5.5e-56 pduU E BMC
NCMBECOF_01353 9.6e-149 3.1.3.48 T Pfam:Y_phosphatase3C
NCMBECOF_01354 1.3e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
NCMBECOF_01355 6.9e-77 P Cadmium resistance transporter
NCMBECOF_01356 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
NCMBECOF_01357 3.9e-78 fld C Flavodoxin
NCMBECOF_01358 1.5e-155 XK27_04590 S NADPH-dependent FMN reductase
NCMBECOF_01359 6.3e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
NCMBECOF_01360 2.5e-250 L PFAM transposase, IS4 family protein
NCMBECOF_01361 7e-283 pipD E Dipeptidase
NCMBECOF_01362 3.6e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NCMBECOF_01363 8.9e-133 gntR K UbiC transcription regulator-associated domain protein
NCMBECOF_01364 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NCMBECOF_01365 4.7e-244 yagE E amino acid
NCMBECOF_01366 8.5e-139 aroD S Serine hydrolase (FSH1)
NCMBECOF_01367 1.4e-239 L transposase, IS605 OrfB family
NCMBECOF_01368 1.3e-81 tlpA2 L Transposase IS200 like
NCMBECOF_01369 1.4e-240 brnQ U Component of the transport system for branched-chain amino acids
NCMBECOF_01370 5.2e-167 GK ROK family
NCMBECOF_01371 0.0 tetP J elongation factor G
NCMBECOF_01372 5.1e-81 uspA T universal stress protein
NCMBECOF_01373 3.9e-195 lplA 6.3.1.20 H Lipoate-protein ligase
NCMBECOF_01374 7.1e-63
NCMBECOF_01375 5.2e-14
NCMBECOF_01376 3.3e-108
NCMBECOF_01377 9.7e-134 V ABC transporter
NCMBECOF_01378 4.5e-211 EGP Major facilitator Superfamily
NCMBECOF_01379 5e-257 G PTS system Galactitol-specific IIC component
NCMBECOF_01380 6.7e-33 1.6.5.5 C Zinc-binding dehydrogenase
NCMBECOF_01381 2.9e-117 1.6.5.5 C Zinc-binding dehydrogenase
NCMBECOF_01382 7e-161
NCMBECOF_01383 1e-72 K Transcriptional regulator
NCMBECOF_01384 6.9e-189 D Alpha beta
NCMBECOF_01385 5.4e-51 ypaA S Protein of unknown function (DUF1304)
NCMBECOF_01386 0.0 yjcE P Sodium proton antiporter
NCMBECOF_01387 1.6e-52 yvlA
NCMBECOF_01388 6.3e-114 P Cobalt transport protein
NCMBECOF_01389 1.5e-250 cbiO1 S ABC transporter, ATP-binding protein
NCMBECOF_01390 1.3e-96 S ABC-type cobalt transport system, permease component
NCMBECOF_01391 1.6e-132 S membrane transporter protein
NCMBECOF_01392 7.3e-138 IQ KR domain
NCMBECOF_01393 2.8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
NCMBECOF_01394 4.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NCMBECOF_01395 1.4e-189 L PFAM Integrase catalytic region
NCMBECOF_01396 7.3e-38 agrA K LytTr DNA-binding domain
NCMBECOF_01397 1.2e-18 S Domain of unknown function (DUF4767)
NCMBECOF_01398 7.6e-07
NCMBECOF_01399 2.2e-105 L PFAM transposase, IS4 family protein
NCMBECOF_01400 5.7e-135 L PFAM transposase, IS4 family protein
NCMBECOF_01401 1.6e-42
NCMBECOF_01404 7.1e-24 S Domain of unknown function (DUF4767)
NCMBECOF_01406 6.2e-157 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NCMBECOF_01407 3.6e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NCMBECOF_01408 2.1e-255 yagE E amino acid
NCMBECOF_01409 2.6e-85 dps P Belongs to the Dps family
NCMBECOF_01410 0.0 pacL 3.6.3.8 P P-type ATPase
NCMBECOF_01411 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NCMBECOF_01412 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NCMBECOF_01413 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NCMBECOF_01414 4.5e-146 potB P ABC transporter permease
NCMBECOF_01415 4.9e-140 potC P ABC transporter permease
NCMBECOF_01416 6.6e-209 potD P ABC transporter
NCMBECOF_01417 5.6e-231
NCMBECOF_01418 2.8e-230 EGP Sugar (and other) transporter
NCMBECOF_01419 5.4e-256 yfnA E Amino Acid
NCMBECOF_01420 2.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NCMBECOF_01421 2.2e-102 gmk2 2.7.4.8 F Guanylate kinase
NCMBECOF_01422 1.5e-82 zur P Belongs to the Fur family
NCMBECOF_01423 1.2e-16 3.2.1.14 GH18
NCMBECOF_01424 2e-152
NCMBECOF_01425 4.4e-39 pspC KT PspC domain protein
NCMBECOF_01426 1.6e-94 K Transcriptional regulator (TetR family)
NCMBECOF_01427 7.6e-228 V domain protein
NCMBECOF_01428 1.4e-164 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NCMBECOF_01430 6.1e-33 S Transglycosylase associated protein
NCMBECOF_01431 1.4e-10
NCMBECOF_01432 8.3e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NCMBECOF_01433 5e-127 3.1.3.73 G phosphoglycerate mutase
NCMBECOF_01434 3.4e-115 dedA S SNARE associated Golgi protein
NCMBECOF_01435 0.0 helD 3.6.4.12 L DNA helicase
NCMBECOF_01436 1.3e-243 nox C NADH oxidase
NCMBECOF_01437 7.2e-253 nox C NADH oxidase
NCMBECOF_01438 1.6e-160 EG EamA-like transporter family
NCMBECOF_01439 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NCMBECOF_01440 1.4e-175 coaA 2.7.1.33 F Pantothenic acid kinase
NCMBECOF_01441 2.9e-221 S cog cog1373
NCMBECOF_01443 1.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NCMBECOF_01444 1.9e-113 mloB K Putative ATP-dependent DNA helicase recG C-terminal
NCMBECOF_01447 7e-160 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NCMBECOF_01448 6.8e-43 hxlR K Transcriptional regulator, HxlR family
NCMBECOF_01449 1.7e-17 L Transposase
NCMBECOF_01451 1.6e-157 spoU 2.1.1.185 J Methyltransferase
NCMBECOF_01452 1.3e-262 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01453 5.1e-99 ywlG S Belongs to the UPF0340 family
NCMBECOF_01454 1.9e-193 EGP Major facilitator Superfamily
NCMBECOF_01455 1.1e-120 M Lysin motif
NCMBECOF_01456 2.1e-79
NCMBECOF_01457 2.8e-168 P CorA-like Mg2+ transporter protein
NCMBECOF_01458 5.3e-95 wecD3 K PFAM GCN5-related N-acetyltransferase
NCMBECOF_01459 4.3e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
NCMBECOF_01460 4.3e-13
NCMBECOF_01461 7.2e-77 S Domain of unknown function (DUF4767)
NCMBECOF_01462 3.3e-197 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NCMBECOF_01463 9.2e-115 S Membrane
NCMBECOF_01464 5.4e-124 O Zinc-dependent metalloprotease
NCMBECOF_01465 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NCMBECOF_01466 1e-156 metQ_4 P Belongs to the nlpA lipoprotein family
NCMBECOF_01467 0.0 UW LPXTG-motif cell wall anchor domain protein
NCMBECOF_01468 5.1e-109 UW LPXTG-motif cell wall anchor domain protein
NCMBECOF_01469 0.0 UW LPXTG-motif cell wall anchor domain protein
NCMBECOF_01470 0.0 UW LPXTG-motif cell wall anchor domain protein
NCMBECOF_01471 8.4e-183 S Phosphotransferase system, EIIC
NCMBECOF_01472 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NCMBECOF_01473 6.1e-164
NCMBECOF_01474 3.7e-29 manA 5.3.1.8 G mannose-6-phosphate isomerase
NCMBECOF_01475 1.2e-97 2.3.1.128 K acetyltransferase
NCMBECOF_01476 2.7e-188
NCMBECOF_01477 4.4e-17 K Transcriptional regulator, HxlR family
NCMBECOF_01478 8.1e-224 P ammonium transporter
NCMBECOF_01479 7.8e-99 ureI S AmiS/UreI family transporter
NCMBECOF_01480 4e-47 ureA 3.5.1.5 E Urease, gamma subunit
NCMBECOF_01481 3.8e-63 ureB 3.5.1.5 E Urease beta subunit
NCMBECOF_01482 0.0 ureC 3.5.1.5 E Amidohydrolase family
NCMBECOF_01483 2.5e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NCMBECOF_01484 1.9e-132 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NCMBECOF_01485 3.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NCMBECOF_01486 2e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NCMBECOF_01487 4.9e-42 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCMBECOF_01488 1.9e-30 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NCMBECOF_01489 8.2e-185 nikMN P PDGLE domain
NCMBECOF_01490 3.8e-135 P Cobalt transport protein
NCMBECOF_01491 8.6e-136 cbiO P ABC transporter
NCMBECOF_01492 4e-130 K Transcriptional regulatory protein, C-terminal domain protein
NCMBECOF_01493 9.6e-158 pstS P Phosphate
NCMBECOF_01494 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
NCMBECOF_01495 2.5e-153 pstA P Phosphate transport system permease protein PstA
NCMBECOF_01496 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NCMBECOF_01497 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
NCMBECOF_01498 4e-140
NCMBECOF_01500 4.6e-241 ydaM M Glycosyl transferase
NCMBECOF_01501 1.4e-220 G Glycosyl hydrolases family 8
NCMBECOF_01502 1.8e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NCMBECOF_01503 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NCMBECOF_01504 1e-238 ktrB P Potassium uptake protein
NCMBECOF_01505 1.4e-116 ktrA P domain protein
NCMBECOF_01506 1.4e-79 Q Methyltransferase
NCMBECOF_01507 2.2e-105 L PFAM transposase, IS4 family protein
NCMBECOF_01508 5.7e-135 L PFAM transposase, IS4 family protein
NCMBECOF_01509 1.3e-54 K Cro/C1-type HTH DNA-binding domain
NCMBECOF_01512 1.1e-231 mntH P H( )-stimulated, divalent metal cation uptake system
NCMBECOF_01513 3.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NCMBECOF_01514 2.2e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NCMBECOF_01515 8.4e-96 S NADPH-dependent FMN reductase
NCMBECOF_01516 2.1e-180 MA20_14895 S Conserved hypothetical protein 698
NCMBECOF_01517 9.3e-135 I alpha/beta hydrolase fold
NCMBECOF_01518 5e-157 lsa S ABC transporter
NCMBECOF_01519 2.7e-97 lsa S ABC transporter
NCMBECOF_01520 5.6e-180 yfeX P Peroxidase
NCMBECOF_01521 7e-110 arcD S C4-dicarboxylate anaerobic carrier
NCMBECOF_01522 5.2e-150 arcD S C4-dicarboxylate anaerobic carrier
NCMBECOF_01523 2.3e-259 ytjP 3.5.1.18 E Dipeptidase
NCMBECOF_01524 3.5e-214 uhpT EGP Major facilitator Superfamily
NCMBECOF_01525 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NCMBECOF_01526 3.5e-130 ponA V Beta-lactamase enzyme family
NCMBECOF_01527 6.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NCMBECOF_01528 6.7e-75
NCMBECOF_01529 2.8e-202 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01530 9.5e-52 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01531 1.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NCMBECOF_01532 5.8e-22
NCMBECOF_01533 3.5e-263 S Uncharacterized protein conserved in bacteria (DUF2252)
NCMBECOF_01534 1.6e-168 L transposase, IS605 OrfB family
NCMBECOF_01535 6.8e-300 L PFAM plasmid pRiA4b ORF-3 family protein
NCMBECOF_01536 3.9e-206 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NCMBECOF_01537 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NCMBECOF_01538 2.4e-156 mleR K LysR family
NCMBECOF_01539 1.8e-303 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NCMBECOF_01540 8.1e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NCMBECOF_01541 2.4e-267 frdC 1.3.5.4 C FAD binding domain
NCMBECOF_01542 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
NCMBECOF_01543 5.2e-159 mleR K LysR family
NCMBECOF_01544 4.7e-252 yjjP S Putative threonine/serine exporter
NCMBECOF_01545 5.5e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
NCMBECOF_01546 8.2e-266 emrY EGP Major facilitator Superfamily
NCMBECOF_01547 1.8e-184 I Alpha beta
NCMBECOF_01548 5.7e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NCMBECOF_01549 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NCMBECOF_01551 9.9e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NCMBECOF_01552 3.3e-119 S Domain of unknown function (DUF4811)
NCMBECOF_01553 7.2e-270 lmrB EGP Major facilitator Superfamily
NCMBECOF_01554 3.4e-74 merR K MerR HTH family regulatory protein
NCMBECOF_01555 6.7e-54
NCMBECOF_01556 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NCMBECOF_01557 2.9e-218 S CAAX protease self-immunity
NCMBECOF_01558 1.4e-108 glnP P ABC transporter permease
NCMBECOF_01559 5.4e-110 gluC P ABC transporter permease
NCMBECOF_01560 9.7e-152 glnH ET ABC transporter
NCMBECOF_01561 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NCMBECOF_01562 2.7e-82 usp1 T Belongs to the universal stress protein A family
NCMBECOF_01563 2.2e-109 S VIT family
NCMBECOF_01564 1.2e-115 S membrane
NCMBECOF_01565 3.5e-166 czcD P cation diffusion facilitator family transporter
NCMBECOF_01566 2.4e-124 sirR K iron dependent repressor
NCMBECOF_01567 1.1e-29 cspC K Cold shock protein
NCMBECOF_01568 4e-128 thrE S Putative threonine/serine exporter
NCMBECOF_01569 2.1e-82 S Threonine/Serine exporter, ThrE
NCMBECOF_01570 2.3e-119 lssY 3.6.1.27 I phosphatase
NCMBECOF_01571 2.4e-11 2.3.1.128 J Acetyltransferase (GNAT) domain
NCMBECOF_01572 4.3e-275 lysP E amino acid
NCMBECOF_01573 2.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NCMBECOF_01579 8.9e-181 S Hydrolases of the alpha beta superfamily
NCMBECOF_01580 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
NCMBECOF_01581 4.4e-77 ctsR K Belongs to the CtsR family
NCMBECOF_01582 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NCMBECOF_01583 1e-110 K Bacterial regulatory proteins, tetR family
NCMBECOF_01584 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCMBECOF_01585 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCMBECOF_01586 1.5e-198 ykiI
NCMBECOF_01587 5.2e-111 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NCMBECOF_01588 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NCMBECOF_01589 1.2e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NCMBECOF_01590 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NCMBECOF_01591 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NCMBECOF_01592 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NCMBECOF_01593 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
NCMBECOF_01594 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NCMBECOF_01595 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NCMBECOF_01596 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NCMBECOF_01597 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NCMBECOF_01598 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NCMBECOF_01599 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NCMBECOF_01600 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
NCMBECOF_01601 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NCMBECOF_01602 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NCMBECOF_01603 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NCMBECOF_01604 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NCMBECOF_01605 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NCMBECOF_01606 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NCMBECOF_01607 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NCMBECOF_01608 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NCMBECOF_01609 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NCMBECOF_01610 2.9e-24 rpmD J Ribosomal protein L30
NCMBECOF_01611 8.9e-64 rplO J Binds to the 23S rRNA
NCMBECOF_01612 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NCMBECOF_01613 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NCMBECOF_01614 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NCMBECOF_01615 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NCMBECOF_01616 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NCMBECOF_01617 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NCMBECOF_01618 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NCMBECOF_01619 1.1e-62 rplQ J Ribosomal protein L17
NCMBECOF_01620 3.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NCMBECOF_01621 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NCMBECOF_01622 2e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NCMBECOF_01623 1.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NCMBECOF_01624 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NCMBECOF_01625 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NCMBECOF_01626 2.7e-140 IQ reductase
NCMBECOF_01627 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
NCMBECOF_01628 3.3e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NCMBECOF_01629 5.5e-214 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NCMBECOF_01630 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NCMBECOF_01631 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NCMBECOF_01632 3.3e-203 camS S sex pheromone
NCMBECOF_01633 3.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NCMBECOF_01634 5.9e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NCMBECOF_01635 5.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NCMBECOF_01636 1.9e-186 yegS 2.7.1.107 G Lipid kinase
NCMBECOF_01637 6e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NCMBECOF_01638 2e-83 EGP Sugar (and other) transporter
NCMBECOF_01639 3e-173 S Domain of unknown function (DUF389)
NCMBECOF_01640 3.2e-66 yjdF S Protein of unknown function (DUF2992)
NCMBECOF_01641 9.9e-48 K Psort location Cytoplasmic, score
NCMBECOF_01642 8.7e-18 K Transcriptional regulator
NCMBECOF_01643 7.6e-91 entB 3.5.1.19 Q Isochorismatase family
NCMBECOF_01644 2.1e-91 K Bacterial regulatory proteins, tetR family
NCMBECOF_01645 1.7e-73 1.6.5.2 S NADPH-dependent FMN reductase
NCMBECOF_01646 1.4e-189 L PFAM Integrase catalytic region
NCMBECOF_01647 4.6e-71 S PFAM Archaeal ATPase
NCMBECOF_01648 1.6e-134 L PFAM Integrase catalytic region
NCMBECOF_01649 2.3e-69 S PFAM Archaeal ATPase
NCMBECOF_01650 4.9e-87 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NCMBECOF_01651 3e-207 amtB P ammonium transporter
NCMBECOF_01652 4.3e-250 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NCMBECOF_01653 4.3e-75 yvbK 3.1.3.25 K GNAT family
NCMBECOF_01654 2.5e-92
NCMBECOF_01655 1.5e-123 pnb C nitroreductase
NCMBECOF_01656 3e-262 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01657 6.8e-154 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NCMBECOF_01658 1e-67 S Protein of unknown function (DUF3021)
NCMBECOF_01659 5.4e-77 K LytTr DNA-binding domain
NCMBECOF_01660 9.4e-21
NCMBECOF_01661 8.2e-205 yhjX P Major Facilitator Superfamily
NCMBECOF_01662 1.9e-119 ybhL S Belongs to the BI1 family
NCMBECOF_01663 2.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NCMBECOF_01664 3.4e-191 S Protein of unknown function (DUF3114)
NCMBECOF_01665 8e-293 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NCMBECOF_01666 7.7e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NCMBECOF_01667 2.5e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NCMBECOF_01668 9.1e-62 S Domain of unknown function (DUF4828)
NCMBECOF_01669 4.5e-191 mocA S Oxidoreductase
NCMBECOF_01670 4.3e-231 yfmL L DEAD DEAH box helicase
NCMBECOF_01672 1.6e-210 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NCMBECOF_01673 5.4e-56
NCMBECOF_01674 1.9e-74 gtcA S Teichoic acid glycosylation protein
NCMBECOF_01675 6.1e-79 fld C Flavodoxin
NCMBECOF_01676 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
NCMBECOF_01677 2.3e-220 arcT 2.6.1.1 E Aminotransferase
NCMBECOF_01678 1e-257 E Arginine ornithine antiporter
NCMBECOF_01679 6.2e-282 yjeM E Amino Acid
NCMBECOF_01680 3.1e-151 yihY S Belongs to the UPF0761 family
NCMBECOF_01681 1.9e-33 S Protein of unknown function (DUF2922)
NCMBECOF_01682 2.2e-31
NCMBECOF_01683 2.5e-250 L PFAM transposase, IS4 family protein
NCMBECOF_01684 3.8e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
NCMBECOF_01685 3.2e-149 cps1D M Domain of unknown function (DUF4422)
NCMBECOF_01686 6.3e-176 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NCMBECOF_01687 1.5e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
NCMBECOF_01688 0.0 2.7.7.6 M Peptidase family M23
NCMBECOF_01689 0.0 G Peptidase_C39 like family
NCMBECOF_01690 2.7e-25
NCMBECOF_01691 4.7e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
NCMBECOF_01692 7.7e-213 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NCMBECOF_01693 7.3e-92 cps3B S Glycosyltransferase like family 2
NCMBECOF_01694 5.8e-89 cps3F
NCMBECOF_01695 2.2e-39 M biosynthesis protein
NCMBECOF_01696 4e-72 rgpB GT2 M Glycosyl transferase family 2
NCMBECOF_01697 1e-70 S Glycosyltransferase like family
NCMBECOF_01698 4.3e-81 glfT1 1.1.1.133 S Glycosyltransferase like family 2
NCMBECOF_01699 6.8e-83 S Bacterial membrane protein, YfhO
NCMBECOF_01700 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NCMBECOF_01701 1.6e-225 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NCMBECOF_01702 1.4e-164 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NCMBECOF_01703 4.2e-109 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NCMBECOF_01704 2.7e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NCMBECOF_01705 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NCMBECOF_01706 2.4e-231 csd1 3.5.1.28 G domain, Protein
NCMBECOF_01707 1.3e-245 csd1 3.5.1.28 G domain, Protein
NCMBECOF_01708 3e-164 yueF S AI-2E family transporter
NCMBECOF_01709 4.4e-232 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NCMBECOF_01710 2e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NCMBECOF_01711 0.0 M NlpC/P60 family
NCMBECOF_01712 0.0 S Peptidase, M23
NCMBECOF_01713 0.0 bamA GM domain, Protein
NCMBECOF_01714 9.3e-65 gntR1 K Transcriptional regulator, GntR family
NCMBECOF_01715 3.3e-158 V ABC transporter, ATP-binding protein
NCMBECOF_01716 1e-114
NCMBECOF_01717 2.2e-105 L PFAM transposase, IS4 family protein
NCMBECOF_01718 5.7e-135 L PFAM transposase, IS4 family protein
NCMBECOF_01719 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NCMBECOF_01720 2.8e-100 S Pfam:DUF3816
NCMBECOF_01721 0.0 clpE O Belongs to the ClpA ClpB family
NCMBECOF_01722 8.3e-27
NCMBECOF_01723 2.7e-39 ptsH G phosphocarrier protein HPR
NCMBECOF_01724 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NCMBECOF_01725 3.9e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NCMBECOF_01726 1.6e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
NCMBECOF_01727 1.3e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NCMBECOF_01728 3.3e-39 ykuJ S Protein of unknown function (DUF1797)
NCMBECOF_01731 6.1e-57
NCMBECOF_01742 2.7e-66 XK27_01125 L PFAM IS66 Orf2 family protein
NCMBECOF_01743 3.5e-296 L Transposase IS66 family
NCMBECOF_01744 1.1e-189 L PFAM Integrase catalytic region
NCMBECOF_01745 4.7e-260 L PFAM Integrase catalytic region
NCMBECOF_01746 2.2e-57 yitW S Pfam:DUF59
NCMBECOF_01747 2.9e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NCMBECOF_01748 4.6e-17 K Transcriptional regulator, LacI family
NCMBECOF_01749 1.4e-86 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NCMBECOF_01750 4.4e-85 L Integrase
NCMBECOF_01751 5.8e-27 L PFAM Integrase, catalytic core
NCMBECOF_01752 4.8e-193 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01753 2.2e-236 lmrB EGP Major facilitator Superfamily
NCMBECOF_01754 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NCMBECOF_01755 9.9e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NCMBECOF_01756 8e-160 sufD O Uncharacterized protein family (UPF0051)
NCMBECOF_01757 2.3e-81 lytE M LysM domain protein
NCMBECOF_01758 0.0 oppD EP Psort location Cytoplasmic, score
NCMBECOF_01759 2.3e-93 lytE M LysM domain protein
NCMBECOF_01760 6.3e-25 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
NCMBECOF_01761 8.7e-223 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01762 1.3e-187 L PFAM Integrase catalytic region
NCMBECOF_01763 7.8e-148 xth 3.1.11.2 L exodeoxyribonuclease III
NCMBECOF_01764 3.1e-234 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NCMBECOF_01765 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
NCMBECOF_01766 6.9e-153 yeaE S Aldo keto
NCMBECOF_01767 2.9e-75 hsp O Belongs to the small heat shock protein (HSP20) family
NCMBECOF_01768 4.5e-280 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NCMBECOF_01769 2.9e-78 S Psort location Cytoplasmic, score
NCMBECOF_01770 2.2e-85 S Short repeat of unknown function (DUF308)
NCMBECOF_01771 1e-23
NCMBECOF_01772 4.4e-103 V VanZ like family
NCMBECOF_01773 8.5e-230 cycA E Amino acid permease
NCMBECOF_01774 1.3e-84 perR P Belongs to the Fur family
NCMBECOF_01775 7.9e-258 EGP Major facilitator Superfamily
NCMBECOF_01776 1.6e-91 tag 3.2.2.20 L glycosylase
NCMBECOF_01777 1.2e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NCMBECOF_01778 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NCMBECOF_01779 1.3e-41
NCMBECOF_01780 1.5e-300 ytgP S Polysaccharide biosynthesis protein
NCMBECOF_01781 1.8e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NCMBECOF_01782 6.9e-275 pepV 3.5.1.18 E dipeptidase PepV
NCMBECOF_01783 1.9e-86 uspA T Belongs to the universal stress protein A family
NCMBECOF_01784 7.5e-178 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NCMBECOF_01785 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
NCMBECOF_01786 2.2e-113
NCMBECOF_01787 2.8e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
NCMBECOF_01788 2e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NCMBECOF_01789 1.8e-31
NCMBECOF_01790 1.9e-113 S CAAX protease self-immunity
NCMBECOF_01791 1.9e-43
NCMBECOF_01793 4.4e-70
NCMBECOF_01794 1.4e-53 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NCMBECOF_01795 1.5e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NCMBECOF_01796 3.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NCMBECOF_01797 6.5e-224 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NCMBECOF_01798 1.2e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NCMBECOF_01799 5.3e-212 folP 2.5.1.15 H dihydropteroate synthase
NCMBECOF_01800 5.1e-43
NCMBECOF_01801 2.8e-39
NCMBECOF_01803 2.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NCMBECOF_01804 5.3e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NCMBECOF_01805 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NCMBECOF_01806 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NCMBECOF_01807 4.5e-40 yheA S Belongs to the UPF0342 family
NCMBECOF_01808 5e-218 yhaO L Ser Thr phosphatase family protein
NCMBECOF_01809 0.0 L AAA domain
NCMBECOF_01810 7.7e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NCMBECOF_01812 4.1e-77 hit FG histidine triad
NCMBECOF_01813 4.3e-135 ecsA V ABC transporter, ATP-binding protein
NCMBECOF_01814 6e-219 ecsB U ABC transporter
NCMBECOF_01815 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NCMBECOF_01816 1.9e-183 iolS C Aldo keto reductase
NCMBECOF_01817 1.6e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
NCMBECOF_01818 2.2e-57 ytzB S Small secreted protein
NCMBECOF_01819 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NCMBECOF_01820 6.5e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NCMBECOF_01821 3.4e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NCMBECOF_01822 2.5e-119 ybhL S Belongs to the BI1 family
NCMBECOF_01823 7.5e-118 yoaK S Protein of unknown function (DUF1275)
NCMBECOF_01824 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NCMBECOF_01825 2.6e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NCMBECOF_01826 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NCMBECOF_01827 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NCMBECOF_01828 2e-223 dnaB L replication initiation and membrane attachment
NCMBECOF_01829 8.1e-171 dnaI L Primosomal protein DnaI
NCMBECOF_01830 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NCMBECOF_01831 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NCMBECOF_01832 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NCMBECOF_01833 1.4e-95 yqeG S HAD phosphatase, family IIIA
NCMBECOF_01834 6.9e-217 yqeH S Ribosome biogenesis GTPase YqeH
NCMBECOF_01835 1.9e-47 yhbY J RNA-binding protein
NCMBECOF_01836 8.2e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NCMBECOF_01837 8.1e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NCMBECOF_01838 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NCMBECOF_01839 2.5e-135 yqeM Q Methyltransferase
NCMBECOF_01840 1.3e-207 ylbM S Belongs to the UPF0348 family
NCMBECOF_01841 2.4e-98 yceD S Uncharacterized ACR, COG1399
NCMBECOF_01842 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NCMBECOF_01843 1.5e-121 K response regulator
NCMBECOF_01844 6.3e-279 arlS 2.7.13.3 T Histidine kinase
NCMBECOF_01845 3e-268 yjeM E Amino Acid
NCMBECOF_01846 4.7e-233 V MatE
NCMBECOF_01847 9.3e-71 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NCMBECOF_01848 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NCMBECOF_01849 3.6e-42 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NCMBECOF_01850 2.4e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NCMBECOF_01851 1.8e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NCMBECOF_01852 2e-58 yodB K Transcriptional regulator, HxlR family
NCMBECOF_01853 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NCMBECOF_01854 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NCMBECOF_01855 1e-116 rlpA M PFAM NLP P60 protein
NCMBECOF_01856 1.1e-116 udk 2.7.1.48 F Cytidine monophosphokinase
NCMBECOF_01857 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NCMBECOF_01858 1.1e-68 yneR S Belongs to the HesB IscA family
NCMBECOF_01859 0.0 S membrane
NCMBECOF_01860 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NCMBECOF_01861 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NCMBECOF_01862 8.9e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NCMBECOF_01863 4.8e-109 gluP 3.4.21.105 S Peptidase, S54 family
NCMBECOF_01864 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NCMBECOF_01865 5.6e-183 glk 2.7.1.2 G Glucokinase
NCMBECOF_01866 1e-66 yqhL P Rhodanese-like protein
NCMBECOF_01867 5.9e-22 S Protein of unknown function (DUF3042)
NCMBECOF_01868 6.3e-176 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NCMBECOF_01869 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
NCMBECOF_01870 3.4e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NCMBECOF_01871 9.1e-220 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NCMBECOF_01872 3.9e-12
NCMBECOF_01873 8.1e-202 mod 2.1.1.72 L DNA methylase
NCMBECOF_01874 1.1e-51 mod 2.1.1.72 L DNA methylase
NCMBECOF_01875 1.4e-189 L PFAM Integrase catalytic region
NCMBECOF_01876 3.4e-110 mod 2.1.1.72 L DNA methylase
NCMBECOF_01877 0.0 res 3.1.21.5 L Type III restriction enzyme, res subunit
NCMBECOF_01878 4.7e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NCMBECOF_01879 4.8e-51 S Iron-sulfur cluster assembly protein
NCMBECOF_01880 4.8e-149
NCMBECOF_01881 1.8e-176
NCMBECOF_01882 4.2e-89 dut S Protein conserved in bacteria
NCMBECOF_01883 8.7e-223 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NCMBECOF_01884 9.7e-27 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
NCMBECOF_01887 2.6e-112 K Transcriptional regulator
NCMBECOF_01888 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NCMBECOF_01889 1.8e-53 ysxB J Cysteine protease Prp
NCMBECOF_01890 1e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NCMBECOF_01891 6.2e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NCMBECOF_01892 3.6e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NCMBECOF_01893 1.7e-114 J 2'-5' RNA ligase superfamily
NCMBECOF_01894 6.4e-70 yqhY S Asp23 family, cell envelope-related function
NCMBECOF_01895 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NCMBECOF_01896 3e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NCMBECOF_01897 1.1e-216 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NCMBECOF_01898 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NCMBECOF_01899 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NCMBECOF_01900 1.5e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NCMBECOF_01901 3.3e-77 argR K Regulates arginine biosynthesis genes
NCMBECOF_01902 1.5e-260 recN L May be involved in recombinational repair of damaged DNA
NCMBECOF_01903 3.5e-52
NCMBECOF_01904 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NCMBECOF_01905 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NCMBECOF_01906 4e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NCMBECOF_01907 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NCMBECOF_01908 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NCMBECOF_01909 2.1e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NCMBECOF_01910 5.9e-132 stp 3.1.3.16 T phosphatase
NCMBECOF_01911 0.0 KLT serine threonine protein kinase
NCMBECOF_01912 1.3e-162 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NCMBECOF_01913 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NCMBECOF_01914 6.3e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
NCMBECOF_01915 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NCMBECOF_01916 4.7e-58 asp S Asp23 family, cell envelope-related function
NCMBECOF_01917 0.0 yloV S DAK2 domain fusion protein YloV
NCMBECOF_01918 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NCMBECOF_01919 6.8e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NCMBECOF_01920 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NCMBECOF_01921 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NCMBECOF_01922 0.0 smc D Required for chromosome condensation and partitioning
NCMBECOF_01923 1.8e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NCMBECOF_01924 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NCMBECOF_01925 7.9e-250 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NCMBECOF_01926 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NCMBECOF_01927 4.1e-40 ylqC S Belongs to the UPF0109 family
NCMBECOF_01928 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NCMBECOF_01929 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NCMBECOF_01930 6.8e-262 yfnA E amino acid
NCMBECOF_01931 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NCMBECOF_01932 2.2e-170 L Belongs to the 'phage' integrase family
NCMBECOF_01933 2.8e-46
NCMBECOF_01935 1.7e-41
NCMBECOF_01936 2.9e-10
NCMBECOF_01938 8.5e-34
NCMBECOF_01939 6e-52 S Mazg nucleotide pyrophosphohydrolase
NCMBECOF_01940 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
NCMBECOF_01941 1.1e-83
NCMBECOF_01942 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NCMBECOF_01943 6.3e-112 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NCMBECOF_01944 1.7e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NCMBECOF_01945 1.7e-50 S CRISPR-associated protein (Cas_Csn2)
NCMBECOF_01946 3.7e-173 L transposase, IS605 OrfB family
NCMBECOF_01947 8.8e-187 lacR K Transcriptional regulator
NCMBECOF_01948 0.0 lacS G Transporter
NCMBECOF_01949 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NCMBECOF_01950 6.1e-134 D nuclear chromosome segregation
NCMBECOF_01951 9e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NCMBECOF_01952 2.6e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NCMBECOF_01953 2.6e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NCMBECOF_01954 1.4e-223 mdtG EGP Major facilitator Superfamily
NCMBECOF_01955 6e-165 T Calcineurin-like phosphoesterase superfamily domain
NCMBECOF_01956 9.2e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NCMBECOF_01958 5.1e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NCMBECOF_01959 8.2e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NCMBECOF_01960 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
NCMBECOF_01961 0.0 trxB2 1.8.1.9 C Thioredoxin domain
NCMBECOF_01962 0.0 M LPXTG-motif cell wall anchor domain protein
NCMBECOF_01963 6.9e-82 M family 8
NCMBECOF_01964 8.5e-149 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
NCMBECOF_01965 2.4e-196 M transferase activity, transferring glycosyl groups
NCMBECOF_01966 4.7e-213 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
NCMBECOF_01967 1.6e-155 asp3 S Accessory Sec secretory system ASP3
NCMBECOF_01968 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NCMBECOF_01969 2.2e-226 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NCMBECOF_01970 1.1e-194 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NCMBECOF_01972 8e-92 L Integrase
NCMBECOF_01973 1.8e-160 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NCMBECOF_01974 1.6e-42 hxlR K Transcriptional regulator, HxlR family
NCMBECOF_01975 5.6e-76 natA S ABC transporter, ATP-binding protein
NCMBECOF_01976 1e-59 ysdA CP transmembrane transport
NCMBECOF_01977 1.1e-11 S HTH domain
NCMBECOF_01980 1.8e-10
NCMBECOF_01981 1.3e-82 L Phage integrase, N-terminal SAM-like domain
NCMBECOF_01982 3.4e-36 L Single-strand binding protein family
NCMBECOF_01983 8.8e-102 L Replication initiation factor
NCMBECOF_01984 3.1e-19 S Lysin motif
NCMBECOF_01985 1.5e-19 relB L Addiction module antitoxin, RelB DinJ family
NCMBECOF_01986 1.8e-24
NCMBECOF_01988 7.5e-17
NCMBECOF_01990 7.5e-28 L Replication initiation factor

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)