ORF_ID e_value Gene_name EC_number CAZy COGs Description
IOCCKIGO_00001 6.2e-24 M Glycosyl hydrolases family 25
IOCCKIGO_00006 1e-108 dedA S SNARE-like domain protein
IOCCKIGO_00007 2.9e-111 S Protein of unknown function (DUF1461)
IOCCKIGO_00008 4.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IOCCKIGO_00009 7.4e-100 yutD S Protein of unknown function (DUF1027)
IOCCKIGO_00010 9.7e-117 S Calcineurin-like phosphoesterase
IOCCKIGO_00011 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IOCCKIGO_00012 4.2e-144 ytxK 2.1.1.72 L N-6 DNA Methylase
IOCCKIGO_00013 5.4e-69
IOCCKIGO_00014 5.8e-43
IOCCKIGO_00015 1.4e-77 NU general secretion pathway protein
IOCCKIGO_00016 5.4e-47 comGC U competence protein ComGC
IOCCKIGO_00017 1.9e-181 comGB NU type II secretion system
IOCCKIGO_00018 2.1e-182 comGA NU Type II IV secretion system protein
IOCCKIGO_00019 1e-131 yebC K Transcriptional regulatory protein
IOCCKIGO_00020 1.1e-134
IOCCKIGO_00021 4.5e-183 ccpA K catabolite control protein A
IOCCKIGO_00022 1.2e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IOCCKIGO_00023 8.3e-28
IOCCKIGO_00024 2.2e-33 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IOCCKIGO_00025 1.5e-147 ykuT M mechanosensitive ion channel
IOCCKIGO_00026 1e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
IOCCKIGO_00027 3.6e-76 ykuL S (CBS) domain
IOCCKIGO_00028 2e-94 S Phosphoesterase
IOCCKIGO_00029 2.4e-104 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IOCCKIGO_00030 1.3e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IOCCKIGO_00031 2.3e-96 yslB S Protein of unknown function (DUF2507)
IOCCKIGO_00032 6.1e-54 trxA O Belongs to the thioredoxin family
IOCCKIGO_00033 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IOCCKIGO_00034 1e-85 cvpA S Colicin V production protein
IOCCKIGO_00035 6.1e-48 yrzB S Belongs to the UPF0473 family
IOCCKIGO_00036 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IOCCKIGO_00037 4.1e-43 yrzL S Belongs to the UPF0297 family
IOCCKIGO_00038 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IOCCKIGO_00039 1.4e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IOCCKIGO_00040 1.2e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IOCCKIGO_00041 3e-30 yajC U Preprotein translocase
IOCCKIGO_00042 5.3e-198 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IOCCKIGO_00043 4.5e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IOCCKIGO_00044 6.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IOCCKIGO_00045 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IOCCKIGO_00046 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IOCCKIGO_00047 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
IOCCKIGO_00048 6.5e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IOCCKIGO_00049 3e-229 cinA 3.5.1.42 S Belongs to the CinA family
IOCCKIGO_00050 7.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IOCCKIGO_00051 4.7e-140 ymfM S Helix-turn-helix domain
IOCCKIGO_00052 5.1e-248 ymfH S Peptidase M16
IOCCKIGO_00053 4.3e-228 ymfF S Peptidase M16 inactive domain protein
IOCCKIGO_00054 2.6e-160 aatB ET ABC transporter substrate-binding protein
IOCCKIGO_00055 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOCCKIGO_00056 3.2e-102 glnP P ABC transporter permease
IOCCKIGO_00057 8.7e-93 mreD M rod shape-determining protein MreD
IOCCKIGO_00058 7.7e-152 mreC M Involved in formation and maintenance of cell shape
IOCCKIGO_00059 1.7e-179 mreB D cell shape determining protein MreB
IOCCKIGO_00060 1e-121 radC L DNA repair protein
IOCCKIGO_00061 4.4e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IOCCKIGO_00062 4.5e-230 ndh 1.6.99.3 C NADH dehydrogenase
IOCCKIGO_00063 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IOCCKIGO_00064 4.8e-307 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IOCCKIGO_00065 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IOCCKIGO_00066 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
IOCCKIGO_00067 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IOCCKIGO_00068 1.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IOCCKIGO_00069 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
IOCCKIGO_00074 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IOCCKIGO_00075 1.9e-168
IOCCKIGO_00076 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOCCKIGO_00077 2.4e-242 purD 6.3.4.13 F Belongs to the GARS family
IOCCKIGO_00078 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IOCCKIGO_00079 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IOCCKIGO_00080 1.1e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IOCCKIGO_00081 2.6e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IOCCKIGO_00082 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOCCKIGO_00083 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOCCKIGO_00084 5.5e-34 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IOCCKIGO_00085 4.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IOCCKIGO_00086 1.2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IOCCKIGO_00087 8.3e-218 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IOCCKIGO_00088 3.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IOCCKIGO_00089 2.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IOCCKIGO_00090 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IOCCKIGO_00091 2.2e-186 thrC 4.2.3.1 E Threonine synthase
IOCCKIGO_00092 6.7e-125 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IOCCKIGO_00093 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IOCCKIGO_00094 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IOCCKIGO_00095 6.4e-177 K AI-2E family transporter
IOCCKIGO_00096 1.4e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IOCCKIGO_00097 5.3e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
IOCCKIGO_00098 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IOCCKIGO_00099 7.8e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IOCCKIGO_00100 1.2e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IOCCKIGO_00101 2.4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IOCCKIGO_00102 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IOCCKIGO_00103 6.2e-133 K LysR substrate binding domain
IOCCKIGO_00104 5.6e-53 azlD S branched-chain amino acid
IOCCKIGO_00105 8.5e-141 azlC E AzlC protein
IOCCKIGO_00106 5.9e-200 hpk31 2.7.13.3 T Histidine kinase
IOCCKIGO_00107 3.8e-125 K response regulator
IOCCKIGO_00108 5.9e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOCCKIGO_00109 4.7e-171 deoR K sugar-binding domain protein
IOCCKIGO_00110 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IOCCKIGO_00111 8.1e-238 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
IOCCKIGO_00112 3.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IOCCKIGO_00113 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IOCCKIGO_00114 1e-134 XK27_01040 S Protein of unknown function (DUF1129)
IOCCKIGO_00115 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IOCCKIGO_00116 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
IOCCKIGO_00117 6.5e-154 spo0J K Belongs to the ParB family
IOCCKIGO_00118 3.9e-139 soj D Sporulation initiation inhibitor
IOCCKIGO_00119 7.4e-151 noc K Belongs to the ParB family
IOCCKIGO_00120 1e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IOCCKIGO_00121 4.2e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
IOCCKIGO_00122 1.7e-170 rihC 3.2.2.1 F Nucleoside
IOCCKIGO_00123 1.1e-217 nupG F Nucleoside transporter
IOCCKIGO_00124 2.5e-221 cycA E Amino acid permease
IOCCKIGO_00125 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOCCKIGO_00126 1.8e-265 glnP P ABC transporter
IOCCKIGO_00127 4.2e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IOCCKIGO_00129 2.3e-102 fhaB M Rib/alpha-like repeat
IOCCKIGO_00131 2.1e-18 L Transposase
IOCCKIGO_00132 8e-189 L Transposase
IOCCKIGO_00133 2.6e-234 lmrB EGP Major facilitator Superfamily
IOCCKIGO_00134 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IOCCKIGO_00135 2.4e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IOCCKIGO_00136 1.2e-155 sufD O Uncharacterized protein family (UPF0051)
IOCCKIGO_00137 2.3e-81 lytE M LysM domain protein
IOCCKIGO_00138 0.0 oppD EP Psort location Cytoplasmic, score
IOCCKIGO_00139 2.2e-93 lytE M LysM domain protein
IOCCKIGO_00140 4.9e-150 xth 3.1.11.2 L exodeoxyribonuclease III
IOCCKIGO_00141 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IOCCKIGO_00142 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
IOCCKIGO_00143 4e-153 yeaE S Aldo keto
IOCCKIGO_00144 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
IOCCKIGO_00145 3.1e-281 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
IOCCKIGO_00146 1.3e-78 S Psort location Cytoplasmic, score
IOCCKIGO_00147 2.9e-85 S Short repeat of unknown function (DUF308)
IOCCKIGO_00148 1e-23
IOCCKIGO_00149 1.8e-101 V VanZ like family
IOCCKIGO_00150 3.1e-232 cycA E Amino acid permease
IOCCKIGO_00151 4.3e-85 perR P Belongs to the Fur family
IOCCKIGO_00152 1e-257 EGP Major facilitator Superfamily
IOCCKIGO_00153 2.2e-96 tag 3.2.2.20 L glycosylase
IOCCKIGO_00154 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IOCCKIGO_00155 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOCCKIGO_00156 1.4e-40
IOCCKIGO_00157 3.8e-256 ytgP S Polysaccharide biosynthesis protein
IOCCKIGO_00158 7.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IOCCKIGO_00159 6.2e-276 pepV 3.5.1.18 E dipeptidase PepV
IOCCKIGO_00160 9.5e-86 uspA T Belongs to the universal stress protein A family
IOCCKIGO_00161 6.6e-174 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOCCKIGO_00162 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
IOCCKIGO_00163 2.2e-113
IOCCKIGO_00164 8.2e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
IOCCKIGO_00165 3.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOCCKIGO_00166 2.1e-32
IOCCKIGO_00167 8.3e-117 S CAAX protease self-immunity
IOCCKIGO_00168 1.9e-43
IOCCKIGO_00170 3.8e-69
IOCCKIGO_00171 5.3e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IOCCKIGO_00172 7e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IOCCKIGO_00173 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
IOCCKIGO_00174 1.6e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IOCCKIGO_00175 2.9e-102 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
IOCCKIGO_00176 4.3e-206 folP 2.5.1.15 H dihydropteroate synthase
IOCCKIGO_00177 1.5e-42
IOCCKIGO_00178 1.5e-32
IOCCKIGO_00180 1.1e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOCCKIGO_00181 1.5e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IOCCKIGO_00182 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IOCCKIGO_00183 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IOCCKIGO_00184 3.6e-37 yheA S Belongs to the UPF0342 family
IOCCKIGO_00185 1e-210 yhaO L Ser Thr phosphatase family protein
IOCCKIGO_00186 0.0 L AAA domain
IOCCKIGO_00187 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IOCCKIGO_00189 3.2e-77 hit FG histidine triad
IOCCKIGO_00190 1e-136 ecsA V ABC transporter, ATP-binding protein
IOCCKIGO_00191 1.1e-215 ecsB U ABC transporter
IOCCKIGO_00192 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IOCCKIGO_00193 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IOCCKIGO_00194 1.9e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IOCCKIGO_00195 0.0 S Bacterial membrane protein, YfhO
IOCCKIGO_00196 3.5e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IOCCKIGO_00197 1.1e-169 I alpha/beta hydrolase fold
IOCCKIGO_00198 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IOCCKIGO_00199 1.1e-119 tcyB E ABC transporter
IOCCKIGO_00200 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOCCKIGO_00201 2.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IOCCKIGO_00202 8.1e-265 pepC 3.4.22.40 E Peptidase C1-like family
IOCCKIGO_00203 7.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IOCCKIGO_00204 7.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
IOCCKIGO_00205 1.5e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IOCCKIGO_00206 3.9e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IOCCKIGO_00207 8.6e-207 yacL S domain protein
IOCCKIGO_00208 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOCCKIGO_00209 9.4e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IOCCKIGO_00210 8e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOCCKIGO_00211 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IOCCKIGO_00212 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IOCCKIGO_00213 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
IOCCKIGO_00214 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IOCCKIGO_00215 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IOCCKIGO_00216 2e-227 aadAT EK Aminotransferase, class I
IOCCKIGO_00218 2.9e-235 M Glycosyl transferase family group 2
IOCCKIGO_00219 1.9e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOCCKIGO_00220 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IOCCKIGO_00221 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IOCCKIGO_00222 1e-47
IOCCKIGO_00224 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IOCCKIGO_00225 1.1e-56 K transcriptional regulator PadR family
IOCCKIGO_00226 1.3e-79 XK27_06920 S Protein of unknown function (DUF1700)
IOCCKIGO_00227 1.8e-136 S Putative adhesin
IOCCKIGO_00228 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IOCCKIGO_00229 1.3e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOCCKIGO_00230 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IOCCKIGO_00231 3.4e-35 nrdH O Glutaredoxin
IOCCKIGO_00232 8.6e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IOCCKIGO_00233 1e-278 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOCCKIGO_00234 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IOCCKIGO_00235 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IOCCKIGO_00236 9.7e-39 S Protein of unknown function (DUF2508)
IOCCKIGO_00237 4.3e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IOCCKIGO_00238 7.6e-52 yaaQ S Cyclic-di-AMP receptor
IOCCKIGO_00239 1e-182 holB 2.7.7.7 L DNA polymerase III
IOCCKIGO_00240 5.9e-58 yabA L Involved in initiation control of chromosome replication
IOCCKIGO_00241 6.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IOCCKIGO_00242 2.4e-136 fat 3.1.2.21 I Acyl-ACP thioesterase
IOCCKIGO_00243 2.6e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IOCCKIGO_00244 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IOCCKIGO_00245 3.3e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IOCCKIGO_00246 1.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IOCCKIGO_00247 1.3e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IOCCKIGO_00248 1.6e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IOCCKIGO_00249 8e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IOCCKIGO_00250 4.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOCCKIGO_00251 5.3e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IOCCKIGO_00252 9.9e-138 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IOCCKIGO_00253 1e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IOCCKIGO_00254 1.2e-227 mtnE 2.6.1.83 E Aminotransferase
IOCCKIGO_00255 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOCCKIGO_00256 9.6e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IOCCKIGO_00257 3.1e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IOCCKIGO_00258 1.4e-47 gcvH E glycine cleavage
IOCCKIGO_00259 1.1e-220 rodA D Belongs to the SEDS family
IOCCKIGO_00260 1e-31 S Protein of unknown function (DUF2969)
IOCCKIGO_00261 7.2e-178 mbl D Cell shape determining protein MreB Mrl
IOCCKIGO_00262 7.2e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOCCKIGO_00263 2.2e-33 ywzB S Protein of unknown function (DUF1146)
IOCCKIGO_00264 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IOCCKIGO_00265 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IOCCKIGO_00266 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IOCCKIGO_00267 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IOCCKIGO_00268 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOCCKIGO_00269 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IOCCKIGO_00270 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IOCCKIGO_00271 6.9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
IOCCKIGO_00272 6.5e-232 pyrP F Permease
IOCCKIGO_00273 6.3e-129 yibF S overlaps another CDS with the same product name
IOCCKIGO_00274 1.2e-189 yibE S overlaps another CDS with the same product name
IOCCKIGO_00275 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOCCKIGO_00276 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IOCCKIGO_00277 4.6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IOCCKIGO_00278 4.7e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IOCCKIGO_00279 1.4e-164 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IOCCKIGO_00280 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IOCCKIGO_00281 6e-108 tdk 2.7.1.21 F thymidine kinase
IOCCKIGO_00282 3.7e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
IOCCKIGO_00283 1.6e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
IOCCKIGO_00285 2.7e-223 arcD U Amino acid permease
IOCCKIGO_00286 3.7e-260 E Arginine ornithine antiporter
IOCCKIGO_00287 2.7e-79 argR K Regulates arginine biosynthesis genes
IOCCKIGO_00288 2e-238 arcA 3.5.3.6 E Arginine
IOCCKIGO_00289 9.4e-189 ampC V Beta-lactamase
IOCCKIGO_00290 4.6e-34
IOCCKIGO_00291 0.0 M domain protein
IOCCKIGO_00292 3.1e-92
IOCCKIGO_00294 1.5e-131 L Belongs to the 'phage' integrase family
IOCCKIGO_00295 1.4e-13 xre K sequence-specific DNA binding
IOCCKIGO_00296 1.6e-17 S Helix-turn-helix domain
IOCCKIGO_00298 3.3e-12
IOCCKIGO_00300 2.1e-47
IOCCKIGO_00301 8.9e-106 S D5 N terminal like
IOCCKIGO_00302 6.5e-14 arpU S Phage transcriptional regulator, ArpU family
IOCCKIGO_00308 7.7e-251 yjcE P Sodium proton antiporter
IOCCKIGO_00309 3.6e-57
IOCCKIGO_00311 1.8e-86
IOCCKIGO_00312 0.0 copA 3.6.3.54 P P-type ATPase
IOCCKIGO_00313 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IOCCKIGO_00314 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IOCCKIGO_00315 7.7e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IOCCKIGO_00318 1.3e-193 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IOCCKIGO_00319 1.5e-227 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IOCCKIGO_00320 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOCCKIGO_00321 1.2e-155 asp3 S Accessory Sec secretory system ASP3
IOCCKIGO_00322 5e-215 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
IOCCKIGO_00323 6.2e-197 M transferase activity, transferring glycosyl groups
IOCCKIGO_00324 3e-162 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
IOCCKIGO_00325 3.5e-111 nss M transferase activity, transferring glycosyl groups
IOCCKIGO_00326 3e-56 M family 8
IOCCKIGO_00327 7.6e-11 M Glycosyl transferase family 8
IOCCKIGO_00328 9e-184 L Transposase
IOCCKIGO_00329 1.5e-302 M family 8
IOCCKIGO_00330 7.5e-102 cpsJ S glycosyl transferase family 2
IOCCKIGO_00331 0.0 M LPXTG-motif cell wall anchor domain protein
IOCCKIGO_00332 0.0 trxB2 1.8.1.9 C Thioredoxin domain
IOCCKIGO_00333 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
IOCCKIGO_00334 3.8e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IOCCKIGO_00335 3.9e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IOCCKIGO_00337 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IOCCKIGO_00338 7.1e-166 T Calcineurin-like phosphoesterase superfamily domain
IOCCKIGO_00339 2.4e-223 mdtG EGP Major facilitator Superfamily
IOCCKIGO_00340 1.2e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IOCCKIGO_00341 1.6e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
IOCCKIGO_00342 1.1e-143 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
IOCCKIGO_00343 2.6e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IOCCKIGO_00344 3.3e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOCCKIGO_00345 0.0 lacZ 3.2.1.23 G -beta-galactosidase
IOCCKIGO_00346 0.0 lacS G Transporter
IOCCKIGO_00347 1.4e-187 lacR K Transcriptional regulator
IOCCKIGO_00348 6.6e-84
IOCCKIGO_00349 9.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
IOCCKIGO_00350 8.4e-54 S Mazg nucleotide pyrophosphohydrolase
IOCCKIGO_00351 1.1e-33
IOCCKIGO_00352 7e-181 glmS2 G Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IOCCKIGO_00353 3.1e-153 rbsK 2.7.1.15, 2.7.1.184, 2.7.1.4 G pfkB family carbohydrate kinase
IOCCKIGO_00354 8.9e-125 frlR K UTRA domain
IOCCKIGO_00355 2.4e-133 3.6.3.21 E ABC transporter, ATP-binding protein
IOCCKIGO_00356 5.4e-97 arpJ P ABC transporter permease
IOCCKIGO_00357 2.5e-144 ET Bacterial periplasmic substrate-binding proteins
IOCCKIGO_00358 1.3e-151 L Helix-turn-helix domain
IOCCKIGO_00359 4.4e-169 arcC 2.7.2.2 E Belongs to the carbamate kinase family
IOCCKIGO_00360 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IOCCKIGO_00361 2.3e-153 KT YcbB domain
IOCCKIGO_00362 6e-301 xylB 2.7.1.17 G Belongs to the FGGY kinase family
IOCCKIGO_00363 5e-245 xylA 5.3.1.5 G Belongs to the xylose isomerase family
IOCCKIGO_00364 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
IOCCKIGO_00365 1.3e-42 pgdA 3.5.1.104 G polysaccharide deacetylase
IOCCKIGO_00366 0.0 3.2.1.55 GH51 G Right handed beta helix region
IOCCKIGO_00367 1.6e-290 xynT G MFS/sugar transport protein
IOCCKIGO_00368 8.6e-173 rhaS2 K Transcriptional regulator, AraC family
IOCCKIGO_00369 1.3e-260 xylT EGP Major facilitator Superfamily
IOCCKIGO_00371 6.1e-216 xylR GK ROK family
IOCCKIGO_00372 3.8e-28
IOCCKIGO_00373 1.7e-262 pgi 5.3.1.9 G Belongs to the GPI family
IOCCKIGO_00374 6.4e-100 lacA 2.3.1.79 S Transferase hexapeptide repeat
IOCCKIGO_00375 2e-155 glcU U sugar transport
IOCCKIGO_00376 2.1e-269 yclK 2.7.13.3 T Histidine kinase
IOCCKIGO_00377 3e-133 K response regulator
IOCCKIGO_00379 6.3e-76 lytE M Lysin motif
IOCCKIGO_00380 1.7e-145 XK27_02985 S Cof-like hydrolase
IOCCKIGO_00381 3.5e-79 K Transcriptional regulator
IOCCKIGO_00382 0.0 oatA I Acyltransferase
IOCCKIGO_00383 1.9e-52
IOCCKIGO_00384 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IOCCKIGO_00385 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IOCCKIGO_00386 1e-122 ybbR S YbbR-like protein
IOCCKIGO_00387 7.2e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IOCCKIGO_00388 1.1e-248 fucP G Major Facilitator Superfamily
IOCCKIGO_00389 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IOCCKIGO_00390 8.5e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IOCCKIGO_00391 7.1e-166 yniA G Phosphotransferase enzyme family
IOCCKIGO_00392 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IOCCKIGO_00393 1.4e-130 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOCCKIGO_00394 1e-260 glnPH2 P ABC transporter permease
IOCCKIGO_00395 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IOCCKIGO_00396 3.8e-70 yqeY S YqeY-like protein
IOCCKIGO_00397 1.2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IOCCKIGO_00398 3.5e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IOCCKIGO_00399 9.5e-261 argH 4.3.2.1 E argininosuccinate lyase
IOCCKIGO_00400 8.2e-73 bioY S BioY family
IOCCKIGO_00401 5.6e-167 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IOCCKIGO_00402 9.9e-183 phoH T phosphate starvation-inducible protein PhoH
IOCCKIGO_00403 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IOCCKIGO_00404 1.9e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IOCCKIGO_00405 1.4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IOCCKIGO_00406 7.8e-143 recO L Involved in DNA repair and RecF pathway recombination
IOCCKIGO_00407 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IOCCKIGO_00408 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IOCCKIGO_00409 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IOCCKIGO_00410 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IOCCKIGO_00411 1.2e-219 patA 2.6.1.1 E Aminotransferase
IOCCKIGO_00412 1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
IOCCKIGO_00413 1.6e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IOCCKIGO_00414 3.9e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IOCCKIGO_00415 2.8e-93 L Belongs to the 'phage' integrase family
IOCCKIGO_00417 5.2e-75
IOCCKIGO_00418 1.8e-18
IOCCKIGO_00419 5.2e-75 E IrrE N-terminal-like domain
IOCCKIGO_00420 3.9e-48 K Cro/C1-type HTH DNA-binding domain
IOCCKIGO_00421 1.3e-15 K Helix-turn-helix XRE-family like proteins
IOCCKIGO_00422 1.2e-07
IOCCKIGO_00426 5.4e-33 S Siphovirus Gp157
IOCCKIGO_00427 1.6e-159 res L Helicase C-terminal domain protein
IOCCKIGO_00428 8.4e-88 L AAA domain
IOCCKIGO_00429 5.6e-34
IOCCKIGO_00430 3.2e-83 S Bifunctional DNA primase/polymerase, N-terminal
IOCCKIGO_00431 4.4e-122 S Virulence-associated protein E
IOCCKIGO_00433 2.7e-58 S VRR_NUC
IOCCKIGO_00435 2.2e-22
IOCCKIGO_00437 1.1e-18
IOCCKIGO_00440 1.8e-79 3.4.21.88 K Peptidase S24-like
IOCCKIGO_00441 2.8e-10 K Helix-turn-helix XRE-family like proteins
IOCCKIGO_00443 1.1e-26 S Domain of unknown function (DUF4145)
IOCCKIGO_00444 4.4e-15 K Cro/C1-type HTH DNA-binding domain
IOCCKIGO_00445 1.7e-19
IOCCKIGO_00448 8.5e-109 L DnaD domain protein
IOCCKIGO_00450 3.1e-69
IOCCKIGO_00451 9.8e-127
IOCCKIGO_00456 3.2e-83 arpU S Phage transcriptional regulator, ArpU family
IOCCKIGO_00457 9e-102 K acetyltransferase
IOCCKIGO_00458 2.6e-35 rplV S ASCH
IOCCKIGO_00459 1.6e-08
IOCCKIGO_00460 8.7e-150 L HNH nucleases
IOCCKIGO_00461 5.8e-77 terS L Phage terminase, small subunit
IOCCKIGO_00462 0.0 terL S overlaps another CDS with the same product name
IOCCKIGO_00465 7.9e-238 S Phage portal protein
IOCCKIGO_00466 1.2e-112 pi136 S Caudovirus prohead serine protease
IOCCKIGO_00467 1.3e-149 S peptidase activity
IOCCKIGO_00468 2.6e-65 S Phage gp6-like head-tail connector protein
IOCCKIGO_00469 6.6e-40 S Phage head-tail joining protein
IOCCKIGO_00470 8.5e-63 S Bacteriophage HK97-gp10, putative tail-component
IOCCKIGO_00471 5.8e-76
IOCCKIGO_00472 9.8e-112
IOCCKIGO_00473 4.6e-23
IOCCKIGO_00474 1.5e-19
IOCCKIGO_00475 0.0 M Phage tail tape measure protein TP901
IOCCKIGO_00476 1.6e-117 S Phage tail protein
IOCCKIGO_00477 9.5e-259 3.4.24.40 M Peptidase family M23
IOCCKIGO_00479 6.1e-158 cotH M CotH kinase protein
IOCCKIGO_00482 1.3e-35 S Bacteriophage holin family
IOCCKIGO_00483 6.9e-56 S Bacteriophage holin of superfamily 6 (Holin_LLH)
IOCCKIGO_00484 4.1e-198 3.5.1.104 M hydrolase, family 25
IOCCKIGO_00487 8.9e-98 S N-acetylmuramoyl-L-alanine amidase activity
IOCCKIGO_00488 1.1e-74 S Bacteriophage holin family
IOCCKIGO_00491 2.7e-205 S peptidoglycan catabolic process
IOCCKIGO_00492 9.5e-64 S Phage tail protein
IOCCKIGO_00493 1.8e-145 S peptidoglycan catabolic process
IOCCKIGO_00494 4.6e-20
IOCCKIGO_00495 1.4e-45 S Pfam:Phage_TAC_12
IOCCKIGO_00496 1.9e-85 S Phage major tail protein 2
IOCCKIGO_00497 2.7e-43
IOCCKIGO_00498 5.5e-43 S exonuclease activity
IOCCKIGO_00499 7.1e-18
IOCCKIGO_00500 8.8e-47 S Phage gp6-like head-tail connector protein
IOCCKIGO_00501 1.5e-115
IOCCKIGO_00502 1.1e-64 S aminoacyl-tRNA ligase activity
IOCCKIGO_00504 1.8e-142 S Phage Mu protein F like protein
IOCCKIGO_00505 3.2e-208 S Phage portal protein, SPP1 Gp6-like
IOCCKIGO_00506 5.7e-236 S Phage terminase, large subunit
IOCCKIGO_00507 2.3e-64 L Terminase small subunit
IOCCKIGO_00508 5.5e-14 S Super-infection exclusion protein B
IOCCKIGO_00509 2.5e-80 arpU S Phage transcriptional regulator, ArpU family
IOCCKIGO_00512 2.3e-37
IOCCKIGO_00515 1.2e-20
IOCCKIGO_00517 4.6e-58 S VRR_NUC
IOCCKIGO_00519 9.1e-231 S Virulence-associated protein E
IOCCKIGO_00520 5.5e-144 S Bifunctional DNA primase/polymerase, N-terminal
IOCCKIGO_00521 1.7e-93
IOCCKIGO_00522 1.2e-140 L AAA domain
IOCCKIGO_00523 5.9e-255 res L Helicase C-terminal domain protein
IOCCKIGO_00524 9.5e-83 S Siphovirus Gp157
IOCCKIGO_00527 2.2e-26
IOCCKIGO_00530 5.7e-39
IOCCKIGO_00532 1.8e-14 XK27_10050 K Peptidase S24-like
IOCCKIGO_00533 1.7e-20 E Zn peptidase
IOCCKIGO_00534 3.2e-28 S Bacterial PH domain
IOCCKIGO_00535 1.5e-18
IOCCKIGO_00536 3e-212 L Belongs to the 'phage' integrase family
IOCCKIGO_00546 0.0 uup S ABC transporter, ATP-binding protein
IOCCKIGO_00547 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IOCCKIGO_00548 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IOCCKIGO_00549 9.4e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IOCCKIGO_00550 3.4e-80 S YbaK proline--tRNA ligase associated domain protein
IOCCKIGO_00551 2.4e-303 ybeC E amino acid
IOCCKIGO_00552 0.0 ydaO E amino acid
IOCCKIGO_00553 3e-38
IOCCKIGO_00554 2.6e-65 rmaI K Transcriptional regulator
IOCCKIGO_00556 1.6e-86 yaaU EGP Major facilitator Superfamily
IOCCKIGO_00557 5.1e-76 EGP Major facilitator Superfamily
IOCCKIGO_00558 9.8e-112 yvyE 3.4.13.9 S YigZ family
IOCCKIGO_00559 6.6e-259 comFA L Helicase C-terminal domain protein
IOCCKIGO_00560 1.2e-126 comFC S Competence protein
IOCCKIGO_00561 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IOCCKIGO_00562 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IOCCKIGO_00563 3.9e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IOCCKIGO_00564 5.3e-32 KT PspC domain protein
IOCCKIGO_00565 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IOCCKIGO_00566 6.6e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IOCCKIGO_00567 1.2e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IOCCKIGO_00568 2.5e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IOCCKIGO_00569 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IOCCKIGO_00570 6.6e-136 yrjD S LUD domain
IOCCKIGO_00571 1.3e-287 lutB C 4Fe-4S dicluster domain
IOCCKIGO_00572 1.7e-156 lutA C Cysteine-rich domain
IOCCKIGO_00573 3.9e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IOCCKIGO_00574 2.4e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IOCCKIGO_00575 8.2e-165 aatB ET PFAM extracellular solute-binding protein, family 3
IOCCKIGO_00576 3.9e-87 ykhA 3.1.2.20 I Thioesterase superfamily
IOCCKIGO_00577 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IOCCKIGO_00578 7.2e-47 L PFAM Integrase catalytic region
IOCCKIGO_00579 3.3e-289 mntH P H( )-stimulated, divalent metal cation uptake system
IOCCKIGO_00580 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
IOCCKIGO_00581 1.2e-86 ygfC K transcriptional regulator (TetR family)
IOCCKIGO_00582 5.4e-171 hrtB V ABC transporter permease
IOCCKIGO_00583 3.9e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IOCCKIGO_00584 0.0 yhcA V ABC transporter, ATP-binding protein
IOCCKIGO_00585 1.3e-37
IOCCKIGO_00586 4.1e-50 czrA K Transcriptional regulator, ArsR family
IOCCKIGO_00587 3.6e-241 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOCCKIGO_00588 8.7e-173 scrR K Transcriptional regulator, LacI family
IOCCKIGO_00589 1e-24
IOCCKIGO_00590 5.5e-107
IOCCKIGO_00591 3.1e-215 yttB EGP Major facilitator Superfamily
IOCCKIGO_00592 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
IOCCKIGO_00593 1.3e-87
IOCCKIGO_00594 1.5e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
IOCCKIGO_00595 2.4e-259 S Putative peptidoglycan binding domain
IOCCKIGO_00596 1.2e-14
IOCCKIGO_00597 1.4e-121 yciB M ErfK YbiS YcfS YnhG
IOCCKIGO_00599 4.6e-100
IOCCKIGO_00600 1.4e-215 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IOCCKIGO_00601 1e-124 S Alpha beta hydrolase
IOCCKIGO_00602 4.4e-208 gldA 1.1.1.6 C dehydrogenase
IOCCKIGO_00603 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOCCKIGO_00604 8.4e-41
IOCCKIGO_00605 7.2e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
IOCCKIGO_00606 1.4e-281 S C4-dicarboxylate anaerobic carrier
IOCCKIGO_00607 8.5e-249 nhaC C Na H antiporter NhaC
IOCCKIGO_00608 1.2e-241 pbuX F xanthine permease
IOCCKIGO_00609 3.9e-281 pipD E Dipeptidase
IOCCKIGO_00610 9.7e-169 corA P CorA-like Mg2+ transporter protein
IOCCKIGO_00611 3.9e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOCCKIGO_00612 6.6e-131 terC P membrane
IOCCKIGO_00613 6.1e-54 trxA O Belongs to the thioredoxin family
IOCCKIGO_00614 1.5e-55 K Transcriptional regulator, ArsR family
IOCCKIGO_00615 1.1e-93 P Cadmium resistance transporter
IOCCKIGO_00616 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
IOCCKIGO_00617 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IOCCKIGO_00618 1.3e-182 ABC-SBP S ABC transporter
IOCCKIGO_00619 5.9e-74 M PFAM NLP P60 protein
IOCCKIGO_00620 6.9e-73 K Transcriptional regulator, TetR family
IOCCKIGO_00621 2.6e-41 3.4.22.70 M Sortase family
IOCCKIGO_00622 1.7e-33 F Belongs to the NrdI family
IOCCKIGO_00624 1.7e-48
IOCCKIGO_00625 2.2e-84 K Helix-turn-helix domain
IOCCKIGO_00626 9.3e-273 S ABC transporter, ATP-binding protein
IOCCKIGO_00627 2.6e-138 S Putative ABC-transporter type IV
IOCCKIGO_00628 9.9e-106 NU mannosyl-glycoprotein
IOCCKIGO_00629 4e-243 brnQ U Component of the transport system for branched-chain amino acids
IOCCKIGO_00630 5e-229 S Uncharacterized protein conserved in bacteria (DUF2325)
IOCCKIGO_00631 5.1e-201 nrnB S DHHA1 domain
IOCCKIGO_00632 3.1e-49
IOCCKIGO_00633 4.4e-123 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IOCCKIGO_00634 1.7e-19 S Domain of unknown function (DUF4767)
IOCCKIGO_00635 3.6e-54
IOCCKIGO_00636 4.6e-115 yrkL S Flavodoxin-like fold
IOCCKIGO_00638 5.3e-65 yeaO S Protein of unknown function, DUF488
IOCCKIGO_00639 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IOCCKIGO_00640 3.5e-200 3.1.3.1 S associated with various cellular activities
IOCCKIGO_00641 6.7e-232 S Putative metallopeptidase domain
IOCCKIGO_00642 2.3e-47
IOCCKIGO_00643 0.0 pepO 3.4.24.71 O Peptidase family M13
IOCCKIGO_00644 5.4e-110 K Helix-turn-helix domain
IOCCKIGO_00645 4.3e-86 ymdB S Macro domain protein
IOCCKIGO_00646 1.1e-193 EGP Major facilitator Superfamily
IOCCKIGO_00647 6.6e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOCCKIGO_00648 6.7e-53 K helix_turn_helix, mercury resistance
IOCCKIGO_00649 1e-165 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IOCCKIGO_00650 8.8e-153 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IOCCKIGO_00651 0.0 ysaB V FtsX-like permease family
IOCCKIGO_00652 1.3e-134 macB2 V ABC transporter, ATP-binding protein
IOCCKIGO_00653 5e-179 T PhoQ Sensor
IOCCKIGO_00654 1.4e-124 K response regulator
IOCCKIGO_00655 7.8e-157 ytbE 1.1.1.346 S Aldo keto reductase
IOCCKIGO_00656 1.2e-135 pnuC H nicotinamide mononucleotide transporter
IOCCKIGO_00657 3.7e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOCCKIGO_00658 9e-201
IOCCKIGO_00659 5.9e-52
IOCCKIGO_00660 9.1e-36
IOCCKIGO_00661 1.2e-91 yxkA S Phosphatidylethanolamine-binding protein
IOCCKIGO_00662 4.9e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
IOCCKIGO_00663 2.1e-177 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
IOCCKIGO_00664 2.2e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IOCCKIGO_00665 8.1e-287 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IOCCKIGO_00666 3.8e-179 galR K Transcriptional regulator
IOCCKIGO_00667 6.6e-97 dedA 3.1.3.1 S SNARE associated Golgi protein
IOCCKIGO_00668 2e-231 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IOCCKIGO_00669 2.5e-80 K AsnC family
IOCCKIGO_00670 1.5e-80 uspA T universal stress protein
IOCCKIGO_00671 0.0 lacS G Transporter
IOCCKIGO_00672 3.9e-38
IOCCKIGO_00673 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IOCCKIGO_00674 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IOCCKIGO_00675 1.7e-191 yeaN P Transporter, major facilitator family protein
IOCCKIGO_00676 1.6e-73 S 3-demethylubiquinone-9 3-methyltransferase
IOCCKIGO_00677 1.3e-84 nrdI F Belongs to the NrdI family
IOCCKIGO_00678 1.5e-242 yhdP S Transporter associated domain
IOCCKIGO_00679 1.7e-154 ypdB V (ABC) transporter
IOCCKIGO_00680 1.1e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
IOCCKIGO_00681 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
IOCCKIGO_00682 1.9e-77 yybA 2.3.1.57 K Transcriptional regulator
IOCCKIGO_00683 1.2e-134 XK27_07210 6.1.1.6 S B3 4 domain
IOCCKIGO_00684 2.3e-172 S AI-2E family transporter
IOCCKIGO_00685 2.6e-160 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IOCCKIGO_00686 5.7e-137
IOCCKIGO_00687 2.1e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IOCCKIGO_00688 1.4e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOCCKIGO_00689 2.4e-309 lmrA V ABC transporter, ATP-binding protein
IOCCKIGO_00690 0.0 yfiC V ABC transporter
IOCCKIGO_00691 1.4e-283 pipD E Dipeptidase
IOCCKIGO_00692 1.6e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IOCCKIGO_00693 2.3e-133 gntR K UbiC transcription regulator-associated domain protein
IOCCKIGO_00694 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IOCCKIGO_00695 1.1e-242 yagE E amino acid
IOCCKIGO_00696 1e-136 aroD S Serine hydrolase (FSH1)
IOCCKIGO_00697 2.2e-241 brnQ U Component of the transport system for branched-chain amino acids
IOCCKIGO_00698 1.4e-167 GK ROK family
IOCCKIGO_00699 0.0 tetP J elongation factor G
IOCCKIGO_00700 5.1e-81 uspA T universal stress protein
IOCCKIGO_00701 4.3e-194 lplA 6.3.1.20 H Lipoate-protein ligase
IOCCKIGO_00702 7.1e-63
IOCCKIGO_00703 5.2e-14
IOCCKIGO_00704 5.5e-111
IOCCKIGO_00705 8.8e-135 V ABC transporter
IOCCKIGO_00706 2.4e-212 EGP Major facilitator Superfamily
IOCCKIGO_00707 1.9e-256 G PTS system Galactitol-specific IIC component
IOCCKIGO_00708 7.9e-76 1.6.5.5 C Zinc-binding dehydrogenase
IOCCKIGO_00709 2.3e-16 1.6.5.5 C Zinc-binding dehydrogenase
IOCCKIGO_00710 4.5e-160
IOCCKIGO_00711 1e-72 K Transcriptional regulator
IOCCKIGO_00712 5.3e-189 D Alpha beta
IOCCKIGO_00713 3.8e-52 ypaA S Protein of unknown function (DUF1304)
IOCCKIGO_00714 0.0 yjcE P Sodium proton antiporter
IOCCKIGO_00715 1.6e-52 yvlA
IOCCKIGO_00716 2.2e-114 P Cobalt transport protein
IOCCKIGO_00717 4.9e-249 cbiO1 S ABC transporter, ATP-binding protein
IOCCKIGO_00718 2.7e-97 S ABC-type cobalt transport system, permease component
IOCCKIGO_00719 3.3e-133 S membrane transporter protein
IOCCKIGO_00720 3.1e-136 IQ KR domain
IOCCKIGO_00721 1.4e-181 iunH2 3.2.2.1 F nucleoside hydrolase
IOCCKIGO_00722 2.2e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IOCCKIGO_00723 1.5e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IOCCKIGO_00724 5.1e-249 yagE E amino acid
IOCCKIGO_00725 2.2e-84 dps P Belongs to the Dps family
IOCCKIGO_00726 0.0 pacL 3.6.3.8 P P-type ATPase
IOCCKIGO_00727 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IOCCKIGO_00728 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IOCCKIGO_00729 5.9e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IOCCKIGO_00730 4.5e-146 potB P ABC transporter permease
IOCCKIGO_00731 1.7e-132 potC P ABC transporter permease
IOCCKIGO_00732 3.3e-208 potD P ABC transporter
IOCCKIGO_00733 4.3e-231
IOCCKIGO_00734 5e-235 EGP Sugar (and other) transporter
IOCCKIGO_00735 3e-254 yfnA E Amino Acid
IOCCKIGO_00736 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IOCCKIGO_00737 6.4e-102 gmk2 2.7.4.8 F Guanylate kinase
IOCCKIGO_00738 1.5e-82 zur P Belongs to the Fur family
IOCCKIGO_00739 1.2e-16 3.2.1.14 GH18
IOCCKIGO_00740 5.4e-150
IOCCKIGO_00741 3.7e-38 pspC KT PspC domain protein
IOCCKIGO_00742 1.6e-94 K Transcriptional regulator (TetR family)
IOCCKIGO_00743 3.1e-221 V domain protein
IOCCKIGO_00744 1.2e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOCCKIGO_00746 6.6e-35 S Transglycosylase associated protein
IOCCKIGO_00747 7e-234 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IOCCKIGO_00748 1.9e-126 G phosphoglycerate mutase
IOCCKIGO_00749 8.8e-116 dedA S SNARE associated Golgi protein
IOCCKIGO_00750 0.0 helD 3.6.4.12 L DNA helicase
IOCCKIGO_00751 1.6e-244 nox C NADH oxidase
IOCCKIGO_00752 1.1e-253 nox C NADH oxidase
IOCCKIGO_00753 2.5e-158 EG EamA-like transporter family
IOCCKIGO_00754 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IOCCKIGO_00755 8.2e-176 coaA 2.7.1.33 F Pantothenic acid kinase
IOCCKIGO_00756 4.3e-225 S cog cog1373
IOCCKIGO_00758 6.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IOCCKIGO_00759 3.3e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOCCKIGO_00760 1.5e-19 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IOCCKIGO_00761 3.9e-15 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IOCCKIGO_00762 7.6e-61 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IOCCKIGO_00763 7.9e-166 cpsY K Transcriptional regulator, LysR family
IOCCKIGO_00764 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IOCCKIGO_00765 7.3e-155 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
IOCCKIGO_00766 9.4e-52 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOCCKIGO_00767 1.8e-55 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOCCKIGO_00769 3.2e-220 L transposase IS116 IS110 IS902 family protein
IOCCKIGO_00770 1.3e-151 L Transposase
IOCCKIGO_00771 1e-69 L Transposase
IOCCKIGO_00772 2.1e-34 L PFAM Integrase catalytic region
IOCCKIGO_00773 3.2e-153 spoU 2.1.1.185 J Methyltransferase
IOCCKIGO_00774 1.2e-80 pnuC H nicotinamide mononucleotide transporter
IOCCKIGO_00775 1.9e-200 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IOCCKIGO_00776 7.1e-101 ywlG S Belongs to the UPF0340 family
IOCCKIGO_00777 1.5e-198 EGP Major facilitator Superfamily
IOCCKIGO_00778 2e-112 M Lysin motif
IOCCKIGO_00779 4.7e-79
IOCCKIGO_00780 2.8e-168 P CorA-like Mg2+ transporter protein
IOCCKIGO_00781 3.1e-95 wecD3 K PFAM GCN5-related N-acetyltransferase
IOCCKIGO_00782 5.8e-195 cytX U Belongs to the purine-cytosine permease (2.A.39) family
IOCCKIGO_00783 4.3e-13
IOCCKIGO_00784 1.2e-76 S Domain of unknown function (DUF4767)
IOCCKIGO_00785 4.1e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IOCCKIGO_00786 1.1e-112 S Membrane
IOCCKIGO_00787 1.8e-122 O Zinc-dependent metalloprotease
IOCCKIGO_00788 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IOCCKIGO_00789 5e-159 metQ_4 P Belongs to the nlpA lipoprotein family
IOCCKIGO_00791 0.0 UW LPXTG-motif cell wall anchor domain protein
IOCCKIGO_00792 5.5e-197 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IOCCKIGO_00793 4.9e-183 S Phosphotransferase system, EIIC
IOCCKIGO_00794 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IOCCKIGO_00795 5.5e-165
IOCCKIGO_00797 3.7e-70 manA 5.3.1.8 G mannose-6-phosphate isomerase
IOCCKIGO_00798 1.2e-94 2.3.1.128 K acetyltransferase
IOCCKIGO_00799 7e-168
IOCCKIGO_00800 7.7e-14 K Transcriptional regulator, HxlR family
IOCCKIGO_00801 2.1e-216 P ammonium transporter
IOCCKIGO_00802 4.4e-94 ureI S AmiS/UreI family transporter
IOCCKIGO_00803 6.5e-45 ureA 3.5.1.5 E Urease, gamma subunit
IOCCKIGO_00804 7.7e-64 ureB 3.5.1.5 E Urease beta subunit
IOCCKIGO_00805 0.0 ureC 3.5.1.5 E Amidohydrolase family
IOCCKIGO_00806 3.3e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IOCCKIGO_00807 6.2e-131 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IOCCKIGO_00808 1.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IOCCKIGO_00809 2.4e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IOCCKIGO_00810 8.2e-41 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOCCKIGO_00811 4.5e-73 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOCCKIGO_00812 1e-182 nikMN P PDGLE domain
IOCCKIGO_00813 6.5e-127 P Cobalt transport protein
IOCCKIGO_00814 8.6e-136 cbiO P ABC transporter
IOCCKIGO_00815 5.1e-133 K Transcriptional regulatory protein, C-terminal domain protein
IOCCKIGO_00816 3.6e-157 pstS P Phosphate
IOCCKIGO_00817 1.2e-152 pstC P probably responsible for the translocation of the substrate across the membrane
IOCCKIGO_00818 1.4e-153 pstA P Phosphate transport system permease protein PstA
IOCCKIGO_00819 4.4e-135 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IOCCKIGO_00820 2.1e-123 phoU P Plays a role in the regulation of phosphate uptake
IOCCKIGO_00821 6.1e-217 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
IOCCKIGO_00822 3.8e-114
IOCCKIGO_00824 1.5e-210 ydaM M Glycosyl transferase
IOCCKIGO_00825 8.6e-167 G Glycosyl hydrolases family 8
IOCCKIGO_00826 2.1e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IOCCKIGO_00827 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
IOCCKIGO_00828 6.5e-238 ktrB P Potassium uptake protein
IOCCKIGO_00829 1.4e-116 ktrA P domain protein
IOCCKIGO_00830 1.2e-81 Q Methyltransferase
IOCCKIGO_00831 1.8e-232 mntH P H( )-stimulated, divalent metal cation uptake system
IOCCKIGO_00832 2.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IOCCKIGO_00833 9.7e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IOCCKIGO_00835 5.6e-84 S NADPH-dependent FMN reductase
IOCCKIGO_00836 3.6e-172 MA20_14895 S Conserved hypothetical protein 698
IOCCKIGO_00837 1.2e-166 L transposase, IS605 OrfB family
IOCCKIGO_00838 1.2e-110 I alpha/beta hydrolase fold
IOCCKIGO_00839 1.7e-128 lsa S ABC transporter
IOCCKIGO_00840 2.3e-173 yfeX P Peroxidase
IOCCKIGO_00841 5.9e-272 arcD S C4-dicarboxylate anaerobic carrier
IOCCKIGO_00842 8.3e-254 ytjP 3.5.1.18 E Dipeptidase
IOCCKIGO_00843 5.9e-214 uhpT EGP Major facilitator Superfamily
IOCCKIGO_00844 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
IOCCKIGO_00845 8.5e-129 ponA V Beta-lactamase enzyme family
IOCCKIGO_00846 1.3e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IOCCKIGO_00847 4.3e-74
IOCCKIGO_00848 4.6e-255 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IOCCKIGO_00849 9.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IOCCKIGO_00850 1.2e-168 murB 1.3.1.98 M Cell wall formation
IOCCKIGO_00851 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
IOCCKIGO_00852 2.9e-75 S PAS domain
IOCCKIGO_00853 3e-87 K Acetyltransferase (GNAT) domain
IOCCKIGO_00854 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IOCCKIGO_00855 4.9e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IOCCKIGO_00856 1.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IOCCKIGO_00857 6.3e-105 yxjI
IOCCKIGO_00858 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IOCCKIGO_00859 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IOCCKIGO_00860 4.4e-146 est 3.1.1.1 S Serine aminopeptidase, S33
IOCCKIGO_00861 1.8e-34 secG U Preprotein translocase
IOCCKIGO_00862 4e-292 clcA P chloride
IOCCKIGO_00863 1.6e-247 yifK E Amino acid permease
IOCCKIGO_00864 3.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IOCCKIGO_00865 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOCCKIGO_00866 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IOCCKIGO_00867 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IOCCKIGO_00869 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IOCCKIGO_00870 4.4e-242 glpT G Major Facilitator Superfamily
IOCCKIGO_00871 8.8e-15
IOCCKIGO_00873 3.1e-170 whiA K May be required for sporulation
IOCCKIGO_00874 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IOCCKIGO_00875 2.7e-160 rapZ S Displays ATPase and GTPase activities
IOCCKIGO_00876 1.1e-245 steT E amino acid
IOCCKIGO_00877 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IOCCKIGO_00878 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IOCCKIGO_00879 6.9e-14
IOCCKIGO_00880 2.3e-116 yfbR S HD containing hydrolase-like enzyme
IOCCKIGO_00881 7.4e-110 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IOCCKIGO_00882 0.0 S SEC-C Motif Domain Protein
IOCCKIGO_00883 2.7e-51
IOCCKIGO_00884 2.8e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IOCCKIGO_00886 1.3e-07 E Collagen triple helix repeat (20 copies)
IOCCKIGO_00888 7.8e-93 M Glycosyl hydrolases family 25
IOCCKIGO_00889 1.7e-41 S Bacteriophage holin of superfamily 6 (Holin_LLH)
IOCCKIGO_00890 9.7e-55 S Bacteriophage holin family
IOCCKIGO_00891 1.2e-64 S Domain of unknown function (DUF2479)
IOCCKIGO_00894 6.7e-187 S Peptidase family M23
IOCCKIGO_00895 8.2e-99 S Phage tail protein
IOCCKIGO_00896 0.0 D NLP P60 protein
IOCCKIGO_00897 5.7e-92 S Phage tail assembly chaperone protein, TAC
IOCCKIGO_00898 1.3e-119
IOCCKIGO_00899 1.2e-70
IOCCKIGO_00900 4.2e-82
IOCCKIGO_00901 2.8e-51
IOCCKIGO_00902 2.2e-63 S Phage gp6-like head-tail connector protein
IOCCKIGO_00903 5.1e-201 gpG
IOCCKIGO_00904 1.3e-106 S Domain of unknown function (DUF4355)
IOCCKIGO_00906 3.8e-176 S Phage Mu protein F like protein
IOCCKIGO_00907 1e-301 S Phage portal protein, SPP1 Gp6-like
IOCCKIGO_00908 1.9e-180 S Phage terminase, large subunit
IOCCKIGO_00909 6.9e-69 S Phage terminase, large subunit
IOCCKIGO_00910 6e-22
IOCCKIGO_00922 1.1e-102 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IOCCKIGO_00923 2.4e-14 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IOCCKIGO_00924 1.5e-133 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IOCCKIGO_00925 1.3e-79 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IOCCKIGO_00926 1.1e-107 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IOCCKIGO_00927 3.4e-58 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IOCCKIGO_00928 6.5e-35 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IOCCKIGO_00929 9.6e-119 IQ reductase
IOCCKIGO_00930 8e-150 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IOCCKIGO_00931 1.8e-13 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOCCKIGO_00932 3.7e-09 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOCCKIGO_00933 3e-51 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOCCKIGO_00934 3.9e-70 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IOCCKIGO_00935 1.8e-75 marR K Transcriptional regulator, MarR family
IOCCKIGO_00936 1.6e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IOCCKIGO_00938 6.2e-199 xerS L Belongs to the 'phage' integrase family
IOCCKIGO_00939 9.1e-83 L PFAM transposase IS200-family protein
IOCCKIGO_00940 3.1e-25 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
IOCCKIGO_00941 1.9e-158 rssA S Phospholipase, patatin family
IOCCKIGO_00942 3.2e-118 L Integrase
IOCCKIGO_00943 9.5e-153 EG EamA-like transporter family
IOCCKIGO_00944 1.9e-129 narI 1.7.5.1 C Nitrate reductase
IOCCKIGO_00945 5.6e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
IOCCKIGO_00946 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
IOCCKIGO_00947 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IOCCKIGO_00948 2.9e-29 moeB 2.7.7.73, 2.7.7.80 H ThiF family
IOCCKIGO_00949 1.2e-88 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
IOCCKIGO_00950 1.7e-218 narK P Transporter, major facilitator family protein
IOCCKIGO_00951 1.7e-35 moaD 2.8.1.12 H ThiS family
IOCCKIGO_00952 2.2e-64 moaE 2.8.1.12 H MoaE protein
IOCCKIGO_00953 4.3e-77 S Flavodoxin
IOCCKIGO_00954 5.2e-131 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IOCCKIGO_00955 5.2e-139 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
IOCCKIGO_00956 1.4e-181 fecB P Periplasmic binding protein
IOCCKIGO_00957 9.8e-180
IOCCKIGO_00958 3.5e-76
IOCCKIGO_00959 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
IOCCKIGO_00960 2.2e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IOCCKIGO_00961 0.0 asnB 6.3.5.4 E Asparagine synthase
IOCCKIGO_00962 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IOCCKIGO_00963 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IOCCKIGO_00964 1.8e-128 jag S R3H domain protein
IOCCKIGO_00965 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOCCKIGO_00966 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IOCCKIGO_00967 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IOCCKIGO_00968 1.9e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IOCCKIGO_00969 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IOCCKIGO_00970 1.7e-34 yaaA S S4 domain protein YaaA
IOCCKIGO_00971 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IOCCKIGO_00972 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOCCKIGO_00973 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IOCCKIGO_00974 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
IOCCKIGO_00975 6.3e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IOCCKIGO_00976 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IOCCKIGO_00977 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IOCCKIGO_00978 2e-74 rplI J Binds to the 23S rRNA
IOCCKIGO_00979 6.9e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IOCCKIGO_00980 9e-207 yttB EGP Major facilitator Superfamily
IOCCKIGO_00981 5.7e-55
IOCCKIGO_00982 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
IOCCKIGO_00983 9.3e-98 K DNA-binding helix-turn-helix protein
IOCCKIGO_00984 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
IOCCKIGO_00985 5.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOCCKIGO_00986 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
IOCCKIGO_00987 6.7e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IOCCKIGO_00988 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IOCCKIGO_00989 2.7e-39 ptsH G phosphocarrier protein HPR
IOCCKIGO_00990 6.4e-27
IOCCKIGO_00991 0.0 clpE O Belongs to the ClpA ClpB family
IOCCKIGO_00992 1.6e-98 S Pfam:DUF3816
IOCCKIGO_00993 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
IOCCKIGO_00994 2.3e-114
IOCCKIGO_00995 6.2e-157 V ABC transporter, ATP-binding protein
IOCCKIGO_00996 9.3e-65 gntR1 K Transcriptional regulator, GntR family
IOCCKIGO_00997 0.0 S Peptidase, M23
IOCCKIGO_00998 6.2e-76 S Peptidase, M23
IOCCKIGO_00999 0.0 M NlpC/P60 family
IOCCKIGO_01000 7.4e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IOCCKIGO_01001 5.8e-224 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOCCKIGO_01002 2e-163 yueF S AI-2E family transporter
IOCCKIGO_01003 3.4e-263 G Peptidase_C39 like family
IOCCKIGO_01004 5.8e-152 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IOCCKIGO_01005 6.6e-21
IOCCKIGO_01006 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IOCCKIGO_01008 1.4e-34 yxiO S Vacuole effluxer Atg22 like
IOCCKIGO_01009 2.7e-22 yxiO S Vacuole effluxer Atg22 like
IOCCKIGO_01010 8.3e-105 yxiO S Vacuole effluxer Atg22 like
IOCCKIGO_01011 1.5e-216 npp S type I phosphodiesterase nucleotide pyrophosphatase
IOCCKIGO_01012 1.2e-239 E amino acid
IOCCKIGO_01013 1.2e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IOCCKIGO_01014 8.8e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
IOCCKIGO_01015 2.5e-39 S Cytochrome B5
IOCCKIGO_01016 5.4e-09 S Cytochrome B5
IOCCKIGO_01017 2.7e-38 S Cytochrome B5
IOCCKIGO_01018 4.8e-73 elaA S Gnat family
IOCCKIGO_01019 3e-10 GM NmrA-like family
IOCCKIGO_01020 2.8e-51 hxlR K Transcriptional regulator, HxlR family
IOCCKIGO_01021 9.1e-107 XK27_02070 S Nitroreductase family
IOCCKIGO_01022 2.9e-57 K Transcriptional regulator, HxlR family
IOCCKIGO_01023 3.5e-236
IOCCKIGO_01024 8.5e-210 EGP Major facilitator Superfamily
IOCCKIGO_01025 4.8e-254 pepC 3.4.22.40 E aminopeptidase
IOCCKIGO_01026 1.1e-110 ylbE GM NAD dependent epimerase dehydratase family protein
IOCCKIGO_01027 0.0 pepN 3.4.11.2 E aminopeptidase
IOCCKIGO_01028 6.5e-91 folT S ECF transporter, substrate-specific component
IOCCKIGO_01029 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
IOCCKIGO_01030 2.7e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IOCCKIGO_01031 2.1e-90 ntd 2.4.2.6 F Nucleoside
IOCCKIGO_01032 3.4e-21
IOCCKIGO_01033 3.6e-165 S Alpha/beta hydrolase of unknown function (DUF915)
IOCCKIGO_01034 4.7e-114 yviA S Protein of unknown function (DUF421)
IOCCKIGO_01035 4.5e-71 S Protein of unknown function (DUF3290)
IOCCKIGO_01036 1.3e-41 ybaN S Protein of unknown function (DUF454)
IOCCKIGO_01037 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOCCKIGO_01038 1.4e-150 endA V DNA/RNA non-specific endonuclease
IOCCKIGO_01039 3.9e-254 yifK E Amino acid permease
IOCCKIGO_01041 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IOCCKIGO_01042 2.7e-230 N Uncharacterized conserved protein (DUF2075)
IOCCKIGO_01043 5.1e-122 S SNARE associated Golgi protein
IOCCKIGO_01044 0.0 uvrA3 L excinuclease ABC, A subunit
IOCCKIGO_01045 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOCCKIGO_01046 2.3e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IOCCKIGO_01047 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IOCCKIGO_01048 2.2e-140 S DUF218 domain
IOCCKIGO_01049 0.0 ubiB S ABC1 family
IOCCKIGO_01050 1.9e-245 yhdP S Transporter associated domain
IOCCKIGO_01051 5e-75 copY K Copper transport repressor CopY TcrY
IOCCKIGO_01052 5.3e-243 EGP Major facilitator Superfamily
IOCCKIGO_01053 4.5e-74 yeaL S UPF0756 membrane protein
IOCCKIGO_01054 8.6e-80 yphH S Cupin domain
IOCCKIGO_01055 1e-111 ywnB S NAD(P)H-binding
IOCCKIGO_01056 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
IOCCKIGO_01057 2.9e-257 nhaC C Na H antiporter NhaC
IOCCKIGO_01058 5.4e-184 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IOCCKIGO_01060 4.8e-99 ydeN S Serine hydrolase
IOCCKIGO_01061 4.5e-62 psiE S Phosphate-starvation-inducible E
IOCCKIGO_01062 5.5e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOCCKIGO_01064 5.7e-180 S Aldo keto reductase
IOCCKIGO_01065 1.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
IOCCKIGO_01066 0.0 L Helicase C-terminal domain protein
IOCCKIGO_01068 1.6e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IOCCKIGO_01069 3.3e-55 S Sugar efflux transporter for intercellular exchange
IOCCKIGO_01070 2.1e-126
IOCCKIGO_01071 1.8e-109 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IOCCKIGO_01072 3.2e-309 cadA P P-type ATPase
IOCCKIGO_01073 2.3e-215 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IOCCKIGO_01074 5.8e-74 K Transcriptional regulator
IOCCKIGO_01075 6.6e-162 proX M ABC transporter, substrate-binding protein, QAT family
IOCCKIGO_01076 1.6e-109 proWZ P ABC transporter permease
IOCCKIGO_01077 2.3e-139 proV E ABC transporter, ATP-binding protein
IOCCKIGO_01078 2.2e-103 proW P ABC transporter, permease protein
IOCCKIGO_01079 5.7e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IOCCKIGO_01080 5.7e-65 L nuclease
IOCCKIGO_01081 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IOCCKIGO_01082 6.8e-209 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IOCCKIGO_01083 4.1e-144 ywqE 3.1.3.48 GM PHP domain protein
IOCCKIGO_01084 0.0 snf 2.7.11.1 KL domain protein
IOCCKIGO_01086 8.4e-38
IOCCKIGO_01087 4.8e-66 T Toxin-antitoxin system, toxin component, MazF family
IOCCKIGO_01089 2.1e-126 O Bacterial dnaA protein
IOCCKIGO_01090 9.2e-215 L Integrase core domain
IOCCKIGO_01091 2.6e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
IOCCKIGO_01092 6.7e-270 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
IOCCKIGO_01093 5.3e-185 gadC E amino acid
IOCCKIGO_01094 8.5e-97 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IOCCKIGO_01095 4.9e-262 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IOCCKIGO_01096 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IOCCKIGO_01097 3e-136 S Belongs to the UPF0246 family
IOCCKIGO_01098 1.2e-137 S Membrane
IOCCKIGO_01099 8.9e-74 4.4.1.5 E Glyoxalase
IOCCKIGO_01100 2e-21
IOCCKIGO_01101 2.5e-86 yueI S Protein of unknown function (DUF1694)
IOCCKIGO_01102 2.5e-242 rarA L recombination factor protein RarA
IOCCKIGO_01103 4.4e-46
IOCCKIGO_01104 4.3e-83 usp6 T universal stress protein
IOCCKIGO_01105 3.5e-205 araR K Transcriptional regulator
IOCCKIGO_01106 2.5e-155 ytbE 1.1.1.346 S Aldo keto reductase
IOCCKIGO_01107 3.5e-92 maa 2.3.1.79 S Maltose O-acetyltransferase
IOCCKIGO_01108 6.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IOCCKIGO_01109 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IOCCKIGO_01110 0.0 araB 2.7.1.16 G carbohydrate kinase FGGY
IOCCKIGO_01111 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IOCCKIGO_01112 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IOCCKIGO_01113 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IOCCKIGO_01114 1e-51
IOCCKIGO_01115 2.1e-126 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IOCCKIGO_01116 1.7e-179 prmA J Ribosomal protein L11 methyltransferase
IOCCKIGO_01117 7.5e-58
IOCCKIGO_01118 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOCCKIGO_01119 7.3e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IOCCKIGO_01120 1.7e-273 pipD E Dipeptidase
IOCCKIGO_01121 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IOCCKIGO_01122 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IOCCKIGO_01123 0.0 dnaK O Heat shock 70 kDa protein
IOCCKIGO_01124 4.6e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IOCCKIGO_01125 1.2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IOCCKIGO_01126 1e-63
IOCCKIGO_01127 6.5e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IOCCKIGO_01128 4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IOCCKIGO_01129 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IOCCKIGO_01130 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IOCCKIGO_01131 4.5e-49 ylxQ J ribosomal protein
IOCCKIGO_01132 1e-44 ylxR K Protein of unknown function (DUF448)
IOCCKIGO_01133 1.2e-214 nusA K Participates in both transcription termination and antitermination
IOCCKIGO_01134 1.9e-83 rimP J Required for maturation of 30S ribosomal subunits
IOCCKIGO_01135 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IOCCKIGO_01136 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IOCCKIGO_01137 8.3e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IOCCKIGO_01138 1.7e-137 cdsA 2.7.7.41 I Belongs to the CDS family
IOCCKIGO_01139 5.5e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IOCCKIGO_01140 3.7e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IOCCKIGO_01141 1.3e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IOCCKIGO_01142 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IOCCKIGO_01143 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
IOCCKIGO_01144 3.7e-182 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOCCKIGO_01145 2.3e-47 yazA L GIY-YIG catalytic domain protein
IOCCKIGO_01146 3.2e-141 yabB 2.1.1.223 L Methyltransferase small domain
IOCCKIGO_01147 4.6e-117 plsC 2.3.1.51 I Acyltransferase
IOCCKIGO_01148 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
IOCCKIGO_01149 6.6e-35 ynzC S UPF0291 protein
IOCCKIGO_01150 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IOCCKIGO_01151 8.9e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IOCCKIGO_01152 2.3e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOCCKIGO_01154 3.9e-16
IOCCKIGO_01155 1.3e-20 S Phage gp6-like head-tail connector protein
IOCCKIGO_01156 2.2e-181 S Caudovirus prohead serine protease
IOCCKIGO_01157 2.8e-141 S Phage portal protein
IOCCKIGO_01158 8.5e-203 terL S overlaps another CDS with the same product name
IOCCKIGO_01159 8.5e-23 terS L Phage terminase, small subunit
IOCCKIGO_01160 9.9e-31 L HNH endonuclease
IOCCKIGO_01161 4.4e-14 S head-tail joining protein
IOCCKIGO_01163 1.8e-92 S Phage plasmid primase, P4
IOCCKIGO_01164 2.5e-43 L Bifunctional DNA primase/polymerase, N-terminal
IOCCKIGO_01171 2.1e-56 sip L Belongs to the 'phage' integrase family
IOCCKIGO_01172 8.7e-89
IOCCKIGO_01173 7.8e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IOCCKIGO_01174 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IOCCKIGO_01175 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IOCCKIGO_01176 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IOCCKIGO_01177 3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IOCCKIGO_01178 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IOCCKIGO_01179 4.9e-08
IOCCKIGO_01180 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IOCCKIGO_01181 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
IOCCKIGO_01182 4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IOCCKIGO_01183 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IOCCKIGO_01184 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IOCCKIGO_01185 3.6e-160 S Tetratricopeptide repeat
IOCCKIGO_01186 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOCCKIGO_01187 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IOCCKIGO_01188 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
IOCCKIGO_01189 3.8e-145 holA 2.7.7.7 L DNA polymerase III delta subunit
IOCCKIGO_01190 0.0 comEC S Competence protein ComEC
IOCCKIGO_01191 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
IOCCKIGO_01192 5.8e-80 comEA L Competence protein ComEA
IOCCKIGO_01193 1.6e-199 ylbL T Belongs to the peptidase S16 family
IOCCKIGO_01194 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IOCCKIGO_01195 4.2e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IOCCKIGO_01196 1.1e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IOCCKIGO_01197 7e-223 ftsW D Belongs to the SEDS family
IOCCKIGO_01198 0.0 typA T GTP-binding protein TypA
IOCCKIGO_01199 1.4e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IOCCKIGO_01200 5.1e-47 yktA S Belongs to the UPF0223 family
IOCCKIGO_01201 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
IOCCKIGO_01202 3.9e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IOCCKIGO_01203 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IOCCKIGO_01204 6.8e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IOCCKIGO_01205 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IOCCKIGO_01206 1.3e-79
IOCCKIGO_01207 3.7e-31 ykzG S Belongs to the UPF0356 family
IOCCKIGO_01208 1.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
IOCCKIGO_01209 3.7e-28
IOCCKIGO_01210 6.1e-125 mltD CBM50 M NlpC P60 family protein
IOCCKIGO_01212 6.5e-57
IOCCKIGO_01213 7.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IOCCKIGO_01214 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IOCCKIGO_01215 4.2e-217 patA 2.6.1.1 E Aminotransferase
IOCCKIGO_01216 5e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IOCCKIGO_01217 5.3e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IOCCKIGO_01218 2.5e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IOCCKIGO_01219 6.7e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IOCCKIGO_01220 3.2e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IOCCKIGO_01221 4.6e-260 lysC 2.7.2.4 E Belongs to the aspartokinase family
IOCCKIGO_01222 3.9e-187 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IOCCKIGO_01223 1.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOCCKIGO_01224 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IOCCKIGO_01225 9e-119 S Repeat protein
IOCCKIGO_01226 1.7e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IOCCKIGO_01227 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IOCCKIGO_01228 2.8e-57 XK27_04120 S Putative amino acid metabolism
IOCCKIGO_01229 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
IOCCKIGO_01230 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IOCCKIGO_01232 2.4e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IOCCKIGO_01233 4.2e-32 cspA K Cold shock protein
IOCCKIGO_01234 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IOCCKIGO_01235 1.9e-42 divIVA D DivIVA domain protein
IOCCKIGO_01236 1.7e-145 ylmH S S4 domain protein
IOCCKIGO_01237 1.4e-40 yggT S YGGT family
IOCCKIGO_01238 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IOCCKIGO_01239 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IOCCKIGO_01240 4.3e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IOCCKIGO_01241 6.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IOCCKIGO_01242 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IOCCKIGO_01243 1.7e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IOCCKIGO_01244 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IOCCKIGO_01245 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IOCCKIGO_01246 1.5e-56 ftsL D Cell division protein FtsL
IOCCKIGO_01247 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IOCCKIGO_01248 4.1e-77 mraZ K Belongs to the MraZ family
IOCCKIGO_01249 6.6e-57
IOCCKIGO_01250 1.2e-10 S Protein of unknown function (DUF4044)
IOCCKIGO_01251 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IOCCKIGO_01252 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IOCCKIGO_01253 9.1e-161 rrmA 2.1.1.187 H Methyltransferase
IOCCKIGO_01254 7.8e-183 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IOCCKIGO_01255 1e-281 O Arylsulfotransferase (ASST)
IOCCKIGO_01256 9.1e-298 L Transposase
IOCCKIGO_01257 3.1e-206 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IOCCKIGO_01258 2.3e-218 G Transporter, major facilitator family protein
IOCCKIGO_01259 3.8e-246 E Peptidase family M20/M25/M40
IOCCKIGO_01260 1e-151 K Transcriptional regulator, LysR family
IOCCKIGO_01261 2.3e-55 znuA P Belongs to the bacterial solute-binding protein 9 family
IOCCKIGO_01262 1.4e-64 XK27_06920 S Protein of unknown function (DUF1700)
IOCCKIGO_01263 2e-48 L PFAM transposase IS200-family protein
IOCCKIGO_01264 1.4e-52 entB 3.5.1.19 Q Isochorismatase family
IOCCKIGO_01265 2.8e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IOCCKIGO_01266 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IOCCKIGO_01267 1.3e-168 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IOCCKIGO_01268 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IOCCKIGO_01269 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOCCKIGO_01270 1.6e-255 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IOCCKIGO_01271 9.8e-67 yabR J RNA binding
IOCCKIGO_01272 1.1e-56 divIC D Septum formation initiator
IOCCKIGO_01273 2.1e-39 yabO J S4 domain protein
IOCCKIGO_01274 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IOCCKIGO_01275 2.5e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IOCCKIGO_01276 6.9e-113 S (CBS) domain
IOCCKIGO_01277 2.9e-145 tesE Q hydratase
IOCCKIGO_01278 3.7e-240 codA 3.5.4.1 F cytosine deaminase
IOCCKIGO_01279 1.2e-250 U Belongs to the purine-cytosine permease (2.A.39) family
IOCCKIGO_01280 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
IOCCKIGO_01281 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IOCCKIGO_01282 2.6e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IOCCKIGO_01284 1.3e-290 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOCCKIGO_01285 1.1e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
IOCCKIGO_01286 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IOCCKIGO_01287 6.2e-254 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IOCCKIGO_01288 7.7e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
IOCCKIGO_01289 0.0 sprD D Domain of Unknown Function (DUF1542)
IOCCKIGO_01290 1.5e-248 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IOCCKIGO_01291 3.4e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IOCCKIGO_01292 1.5e-158 htpX O Belongs to the peptidase M48B family
IOCCKIGO_01293 7e-93 lemA S LemA family
IOCCKIGO_01294 8.9e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOCCKIGO_01295 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
IOCCKIGO_01296 3.4e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IOCCKIGO_01297 4.4e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IOCCKIGO_01298 1.2e-123 srtA 3.4.22.70 M sortase family
IOCCKIGO_01299 5.7e-166 S Alpha/beta hydrolase of unknown function (DUF915)
IOCCKIGO_01300 1.7e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IOCCKIGO_01301 4.6e-41 rpmE2 J Ribosomal protein L31
IOCCKIGO_01302 1.3e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IOCCKIGO_01303 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IOCCKIGO_01304 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IOCCKIGO_01305 3e-66 ywiB S Domain of unknown function (DUF1934)
IOCCKIGO_01306 6.7e-145 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IOCCKIGO_01307 1.7e-270 ywfO S HD domain protein
IOCCKIGO_01308 8.4e-148 yxeH S hydrolase
IOCCKIGO_01309 8.1e-49
IOCCKIGO_01310 3.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IOCCKIGO_01311 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IOCCKIGO_01312 2.6e-149 purR 2.4.2.7 F pur operon repressor
IOCCKIGO_01313 4.7e-119 znuB U ABC 3 transport family
IOCCKIGO_01314 2.2e-122 fhuC P ABC transporter
IOCCKIGO_01315 7.4e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
IOCCKIGO_01316 1.2e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IOCCKIGO_01317 6.8e-37 veg S Biofilm formation stimulator VEG
IOCCKIGO_01318 1e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IOCCKIGO_01319 3.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IOCCKIGO_01320 1.1e-155 tatD L hydrolase, TatD family
IOCCKIGO_01321 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IOCCKIGO_01322 6.4e-159 yunF F Protein of unknown function DUF72
IOCCKIGO_01324 8.8e-130 cobB K SIR2 family
IOCCKIGO_01325 1e-176
IOCCKIGO_01326 1.5e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IOCCKIGO_01327 3e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IOCCKIGO_01328 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IOCCKIGO_01329 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IOCCKIGO_01330 8.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
IOCCKIGO_01331 0.0 helD 3.6.4.12 L DNA helicase
IOCCKIGO_01332 1.6e-200 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IOCCKIGO_01333 1.9e-197 clcA P chloride
IOCCKIGO_01334 4.5e-40 L Transposase, IS116 IS110 IS902 family
IOCCKIGO_01336 3.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IOCCKIGO_01337 1.2e-266 yfnA E amino acid
IOCCKIGO_01338 3.5e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IOCCKIGO_01339 4e-41 1.3.5.4 S FMN binding
IOCCKIGO_01340 1.3e-221 norA EGP Major facilitator Superfamily
IOCCKIGO_01341 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IOCCKIGO_01342 5.9e-152 metQ1 P Belongs to the nlpA lipoprotein family
IOCCKIGO_01343 8e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IOCCKIGO_01344 4.1e-103 metI P ABC transporter permease
IOCCKIGO_01345 3.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IOCCKIGO_01346 5.7e-29 clcA P chloride
IOCCKIGO_01347 5.1e-187 clcA P chloride
IOCCKIGO_01351 1.9e-18
IOCCKIGO_01356 2.7e-56 dnaC 3.4.21.53 L IstB-like ATP binding protein
IOCCKIGO_01357 4.3e-45 L Psort location Cytoplasmic, score
IOCCKIGO_01358 1.7e-09 V HNH endonuclease
IOCCKIGO_01359 3.3e-137 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
IOCCKIGO_01360 9.4e-139 recT L RecT family
IOCCKIGO_01364 2.1e-14 K Cro/C1-type HTH DNA-binding domain
IOCCKIGO_01365 4.9e-16
IOCCKIGO_01368 2.6e-114 K BRO family, N-terminal domain
IOCCKIGO_01369 1e-25
IOCCKIGO_01370 7.8e-30 ps115 K Transcriptional regulator, Cro CI family
IOCCKIGO_01371 2.7e-20 E Zn peptidase
IOCCKIGO_01372 4.4e-18
IOCCKIGO_01373 6.5e-83 J Domain of unknown function (DUF4041)
IOCCKIGO_01374 1.8e-92 L Belongs to the 'phage' integrase family
IOCCKIGO_01375 5.1e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IOCCKIGO_01376 3.2e-118 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IOCCKIGO_01377 1.4e-231 clcA_2 P Chloride transporter, ClC family
IOCCKIGO_01378 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IOCCKIGO_01379 9.9e-112 lssY 3.6.1.27 I Acid phosphatase homologues
IOCCKIGO_01382 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IOCCKIGO_01383 1.2e-42 K HxlR-like helix-turn-helix
IOCCKIGO_01384 1.1e-59 S macrophage migration inhibitory factor
IOCCKIGO_01385 2.2e-168 yqiG C Oxidoreductase
IOCCKIGO_01387 2.4e-18
IOCCKIGO_01388 1.3e-263 dtpT U amino acid peptide transporter
IOCCKIGO_01389 2e-149 yjjH S Calcineurin-like phosphoesterase
IOCCKIGO_01392 9.4e-110
IOCCKIGO_01393 1.5e-250 EGP Major facilitator Superfamily
IOCCKIGO_01394 6e-302 aspT P Predicted Permease Membrane Region
IOCCKIGO_01395 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IOCCKIGO_01396 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
IOCCKIGO_01397 4.5e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IOCCKIGO_01398 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IOCCKIGO_01399 0.0 yhgF K Tex-like protein N-terminal domain protein
IOCCKIGO_01400 3.3e-85 ydcK S Belongs to the SprT family
IOCCKIGO_01403 4.6e-64 K helix_turn_helix multiple antibiotic resistance protein
IOCCKIGO_01404 2.4e-251 lmrA 3.6.3.44 V ABC transporter
IOCCKIGO_01406 5.2e-130 K response regulator
IOCCKIGO_01407 0.0 vicK 2.7.13.3 T Histidine kinase
IOCCKIGO_01408 1.5e-247 yycH S YycH protein
IOCCKIGO_01409 4.2e-150 yycI S YycH protein
IOCCKIGO_01410 2.3e-153 vicX 3.1.26.11 S domain protein
IOCCKIGO_01411 1.9e-218 htrA 3.4.21.107 O serine protease
IOCCKIGO_01412 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IOCCKIGO_01413 6e-21 ABC-SBP S ABC transporter
IOCCKIGO_01414 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IOCCKIGO_01415 2.2e-96 S reductase
IOCCKIGO_01416 2.5e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
IOCCKIGO_01417 1.2e-28
IOCCKIGO_01418 3.4e-77 GT4 M Glycosyltransferase Family 4
IOCCKIGO_01419 1.8e-99 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IOCCKIGO_01420 4e-86 M glycosyl transferase group 1
IOCCKIGO_01421 6.4e-159 mnaA 5.1.3.14 M Psort location Cytoplasmic, score 8.87
IOCCKIGO_01422 1.8e-50 GT2 S Glycosyltransferase like family 2
IOCCKIGO_01423 3.5e-104 rfbP M Bacterial sugar transferase
IOCCKIGO_01424 2e-116 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IOCCKIGO_01425 6.9e-140 epsB M biosynthesis protein
IOCCKIGO_01426 1.6e-161 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IOCCKIGO_01427 1.6e-67 K Transcriptional regulator, HxlR family
IOCCKIGO_01428 1.5e-127
IOCCKIGO_01429 5.8e-103 K DNA-templated transcription, initiation
IOCCKIGO_01430 2.8e-35
IOCCKIGO_01431 1.6e-48 S Glycosyltransferase like family 2
IOCCKIGO_01432 2.1e-28 S Glycosyltransferase like family 2
IOCCKIGO_01433 1.9e-29 M PFAM Glycosyl transferase family 2
IOCCKIGO_01434 1.2e-28 M Glycosyltransferase sugar-binding region containing DXD motif
IOCCKIGO_01435 7.5e-73 cps2I S Psort location CytoplasmicMembrane, score
IOCCKIGO_01437 6e-41 GT2,GT4 M Glycosyltransferase GT-D fold
IOCCKIGO_01438 8.8e-67 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
IOCCKIGO_01439 5.3e-87 GT4 G Glycosyl transferase 4-like
IOCCKIGO_01440 2e-48 pglC M Bacterial sugar transferase
IOCCKIGO_01441 1.7e-107 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IOCCKIGO_01442 1.3e-97 epsB M biosynthesis protein
IOCCKIGO_01443 2.2e-64 lacA S transferase hexapeptide repeat
IOCCKIGO_01444 3.7e-146 S Alpha beta hydrolase
IOCCKIGO_01445 1.9e-152 tesE Q hydratase
IOCCKIGO_01446 8.5e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IOCCKIGO_01447 1.2e-227 aadAT EK Aminotransferase, class I
IOCCKIGO_01448 1.1e-152 ypuA S Protein of unknown function (DUF1002)
IOCCKIGO_01449 5.7e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
IOCCKIGO_01450 6e-136 K Transcriptional regulator
IOCCKIGO_01451 2.5e-158 akr5f 1.1.1.346 S reductase
IOCCKIGO_01452 3.5e-61 yneR
IOCCKIGO_01453 6.5e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
IOCCKIGO_01474 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IOCCKIGO_01475 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IOCCKIGO_01476 5.2e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IOCCKIGO_01477 1e-203 coiA 3.6.4.12 S Competence protein
IOCCKIGO_01478 1.7e-265 pipD E Dipeptidase
IOCCKIGO_01479 4.3e-115 yjbH Q Thioredoxin
IOCCKIGO_01480 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
IOCCKIGO_01481 3.9e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IOCCKIGO_01482 2e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IOCCKIGO_01483 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IOCCKIGO_01484 4.8e-90 2.3.1.183 M Acetyltransferase GNAT family
IOCCKIGO_01485 9.1e-161 S reductase
IOCCKIGO_01487 1.9e-07 yiiE S Protein of unknown function (DUF1211)
IOCCKIGO_01489 1.1e-55 K LysR substrate binding domain
IOCCKIGO_01490 1.3e-25 S amidohydrolase
IOCCKIGO_01491 4.2e-231 S amidohydrolase
IOCCKIGO_01492 6.2e-40 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IOCCKIGO_01493 7.1e-86 V ABC transporter, ATP-binding protein
IOCCKIGO_01494 1.7e-27 CP ABC-2 family transporter protein
IOCCKIGO_01495 2.6e-204 2.7.13.3 T GHKL domain
IOCCKIGO_01496 3.8e-134 K LytTr DNA-binding domain
IOCCKIGO_01497 3.2e-110 S Peptidase propeptide and YPEB domain
IOCCKIGO_01498 5.4e-245 T GHKL domain
IOCCKIGO_01499 7.8e-123 T Transcriptional regulatory protein, C terminal
IOCCKIGO_01500 5.5e-44 mleP3 S Membrane transport protein
IOCCKIGO_01502 2.8e-07
IOCCKIGO_01507 1.4e-272 pipD E Dipeptidase
IOCCKIGO_01508 0.0 yjbQ P TrkA C-terminal domain protein
IOCCKIGO_01509 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IOCCKIGO_01510 1.3e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IOCCKIGO_01511 2.2e-82
IOCCKIGO_01513 4.8e-52 L Transposase
IOCCKIGO_01514 5.9e-74 5.1.1.13 M Asp/Glu/Hydantoin racemase
IOCCKIGO_01515 1.4e-33 5.1.1.13 M Asp/Glu/Hydantoin racemase
IOCCKIGO_01516 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
IOCCKIGO_01517 9.9e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IOCCKIGO_01518 1.6e-94 dps P Belongs to the Dps family
IOCCKIGO_01519 1.1e-33 copZ C Heavy-metal-associated domain
IOCCKIGO_01520 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
IOCCKIGO_01521 4.8e-102
IOCCKIGO_01522 2.3e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOCCKIGO_01523 2.5e-186 yegS 2.7.1.107 G Lipid kinase
IOCCKIGO_01524 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOCCKIGO_01525 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IOCCKIGO_01526 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IOCCKIGO_01527 1.2e-202 camS S sex pheromone
IOCCKIGO_01528 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IOCCKIGO_01529 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IOCCKIGO_01530 5.1e-212 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IOCCKIGO_01531 3.5e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IOCCKIGO_01532 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
IOCCKIGO_01533 6.1e-140 IQ reductase
IOCCKIGO_01534 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IOCCKIGO_01535 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IOCCKIGO_01536 4.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IOCCKIGO_01537 1.3e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOCCKIGO_01538 2.9e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOCCKIGO_01539 5.2e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IOCCKIGO_01540 1.1e-62 rplQ J Ribosomal protein L17
IOCCKIGO_01541 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOCCKIGO_01542 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IOCCKIGO_01543 3.6e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IOCCKIGO_01544 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IOCCKIGO_01545 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IOCCKIGO_01546 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IOCCKIGO_01547 4.4e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IOCCKIGO_01548 8.9e-64 rplO J Binds to the 23S rRNA
IOCCKIGO_01549 2.9e-24 rpmD J Ribosomal protein L30
IOCCKIGO_01550 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IOCCKIGO_01551 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IOCCKIGO_01552 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IOCCKIGO_01553 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IOCCKIGO_01554 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IOCCKIGO_01555 7.5e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IOCCKIGO_01556 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IOCCKIGO_01557 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IOCCKIGO_01558 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
IOCCKIGO_01559 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IOCCKIGO_01560 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IOCCKIGO_01561 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IOCCKIGO_01562 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IOCCKIGO_01563 5.4e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IOCCKIGO_01564 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IOCCKIGO_01565 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
IOCCKIGO_01566 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IOCCKIGO_01567 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IOCCKIGO_01568 2.1e-32 L Transposase
IOCCKIGO_01569 4.1e-164 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IOCCKIGO_01570 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IOCCKIGO_01571 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IOCCKIGO_01572 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IOCCKIGO_01573 9.6e-92 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
IOCCKIGO_01574 8.8e-199 ykiI
IOCCKIGO_01575 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOCCKIGO_01576 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IOCCKIGO_01577 1e-110 K Bacterial regulatory proteins, tetR family
IOCCKIGO_01578 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IOCCKIGO_01579 4.4e-77 ctsR K Belongs to the CtsR family
IOCCKIGO_01580 1e-195 adhP 1.1.1.1 C alcohol dehydrogenase
IOCCKIGO_01581 1.8e-178 S Hydrolases of the alpha beta superfamily
IOCCKIGO_01587 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IOCCKIGO_01588 1.1e-275 lysP E amino acid
IOCCKIGO_01589 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
IOCCKIGO_01590 2.7e-120 lssY 3.6.1.27 I phosphatase
IOCCKIGO_01591 1.2e-82 S Threonine/Serine exporter, ThrE
IOCCKIGO_01592 3.5e-132 thrE S Putative threonine/serine exporter
IOCCKIGO_01593 3.5e-31 cspC K Cold shock protein
IOCCKIGO_01594 4.8e-125 sirR K iron dependent repressor
IOCCKIGO_01595 9.1e-167 czcD P cation diffusion facilitator family transporter
IOCCKIGO_01596 5e-117 S membrane
IOCCKIGO_01597 7.6e-110 S VIT family
IOCCKIGO_01598 5.5e-83 usp1 T Belongs to the universal stress protein A family
IOCCKIGO_01599 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IOCCKIGO_01600 1.7e-151 glnH ET ABC transporter
IOCCKIGO_01601 5.4e-110 gluC P ABC transporter permease
IOCCKIGO_01602 3.6e-109 glnP P ABC transporter permease
IOCCKIGO_01603 1.8e-215 S CAAX protease self-immunity
IOCCKIGO_01604 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IOCCKIGO_01605 3e-54
IOCCKIGO_01606 5.2e-75 merR K MerR HTH family regulatory protein
IOCCKIGO_01607 7.2e-270 lmrB EGP Major facilitator Superfamily
IOCCKIGO_01608 5.4e-122 S Domain of unknown function (DUF4811)
IOCCKIGO_01609 4e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IOCCKIGO_01611 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IOCCKIGO_01612 6.8e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
IOCCKIGO_01613 8.1e-23 I Alpha beta
IOCCKIGO_01614 4.4e-152 I Alpha beta
IOCCKIGO_01615 4.5e-283 emrY EGP Major facilitator Superfamily
IOCCKIGO_01616 7.2e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
IOCCKIGO_01617 1.2e-250 yjjP S Putative threonine/serine exporter
IOCCKIGO_01618 6.3e-157 mleR K LysR family
IOCCKIGO_01619 4.2e-112 ydjP I Alpha/beta hydrolase family
IOCCKIGO_01620 5e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IOCCKIGO_01621 1e-271 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IOCCKIGO_01622 5.3e-159 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IOCCKIGO_01623 7.9e-40 citD C Covalent carrier of the coenzyme of citrate lyase
IOCCKIGO_01624 5.7e-149 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IOCCKIGO_01625 4.6e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
IOCCKIGO_01626 1.8e-125 citR K sugar-binding domain protein
IOCCKIGO_01627 1e-164 citP P Sodium:sulfate symporter transmembrane region
IOCCKIGO_01628 3.1e-130 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOCCKIGO_01629 3.6e-268 frdC 1.3.5.4 C FAD binding domain
IOCCKIGO_01630 1.8e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IOCCKIGO_01631 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IOCCKIGO_01632 3.2e-161 mleR K LysR family
IOCCKIGO_01633 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IOCCKIGO_01634 1.6e-204 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
IOCCKIGO_01635 1.5e-291 L PFAM plasmid pRiA4b ORF-3 family protein
IOCCKIGO_01636 7.6e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
IOCCKIGO_01639 9e-37 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IOCCKIGO_01640 3.2e-39 trxA O Belongs to the thioredoxin family
IOCCKIGO_01642 1e-95 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IOCCKIGO_01643 1.2e-139 trxB 1.8.1.9 O Glucose inhibited division protein A
IOCCKIGO_01644 2.8e-24 CO cell redox homeostasis
IOCCKIGO_01645 1.4e-70 M1-798 K Rhodanese Homology Domain
IOCCKIGO_01646 5.1e-42 K HxlR-like helix-turn-helix
IOCCKIGO_01647 1.9e-138 L Bacterial dnaA protein
IOCCKIGO_01648 1.3e-204 L Integrase core domain
IOCCKIGO_01651 3.6e-68 K Bacterial regulatory proteins, tetR family
IOCCKIGO_01652 4.7e-37 S Domain of unknown function (DUF4440)
IOCCKIGO_01653 5.6e-147 qacA EGP Fungal trichothecene efflux pump (TRI12)
IOCCKIGO_01654 6.8e-38 qacA EGP Fungal trichothecene efflux pump (TRI12)
IOCCKIGO_01655 1.8e-40 S Hexapeptide repeat of succinyl-transferase
IOCCKIGO_01656 9.5e-126 C Aldo keto reductase
IOCCKIGO_01657 8.6e-89 GM NAD(P)H-binding
IOCCKIGO_01658 1.7e-138 akr5f 1.1.1.346 S reductase
IOCCKIGO_01659 8.9e-24
IOCCKIGO_01660 7.6e-20 relB L Addiction module antitoxin, RelB DinJ family
IOCCKIGO_01661 1.8e-89 XK27_08850 J Aminoacyl-tRNA editing domain
IOCCKIGO_01662 2.4e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IOCCKIGO_01663 9.2e-192 V Beta-lactamase
IOCCKIGO_01664 8.1e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IOCCKIGO_01665 8e-120 yhiD S MgtC family
IOCCKIGO_01666 5.6e-68 S GyrI-like small molecule binding domain
IOCCKIGO_01667 2.5e-29 S GyrI-like small molecule binding domain
IOCCKIGO_01669 1.3e-114 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IOCCKIGO_01670 3.2e-81
IOCCKIGO_01671 2.9e-144 rfbJ M Glycosyl transferase family 2
IOCCKIGO_01672 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IOCCKIGO_01674 6.8e-12 S Domain of unknown function DUF1829
IOCCKIGO_01675 5.4e-25
IOCCKIGO_01676 6e-100
IOCCKIGO_01677 2.7e-63
IOCCKIGO_01678 4.6e-30
IOCCKIGO_01679 1.6e-149 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IOCCKIGO_01680 1.6e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IOCCKIGO_01681 1.3e-102 fic D Fic/DOC family
IOCCKIGO_01682 3.3e-71
IOCCKIGO_01683 2.9e-72 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
IOCCKIGO_01684 3.1e-156 K Transcriptional regulator
IOCCKIGO_01685 1.1e-81 C Flavodoxin
IOCCKIGO_01686 1.2e-165 S Oxidoreductase, aldo keto reductase family protein
IOCCKIGO_01687 2.3e-53 yphJ 4.1.1.44 S decarboxylase
IOCCKIGO_01688 1.5e-87 V Beta-lactamase
IOCCKIGO_01690 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
IOCCKIGO_01691 7e-45
IOCCKIGO_01695 4.8e-44 V Abi-like protein
IOCCKIGO_01696 1.2e-141 L Belongs to the 'phage' integrase family
IOCCKIGO_01698 4e-49 yrvD S Pfam:DUF1049
IOCCKIGO_01699 9.9e-149 3.1.3.102, 3.1.3.104 S hydrolase
IOCCKIGO_01700 5.8e-289 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IOCCKIGO_01701 8.6e-118 K LytTr DNA-binding domain
IOCCKIGO_01702 5.3e-115 2.7.13.3 T GHKL domain
IOCCKIGO_01703 4.3e-33
IOCCKIGO_01706 9.7e-60 rusA L Endodeoxyribonuclease RusA
IOCCKIGO_01707 1.2e-16
IOCCKIGO_01710 2.5e-32 V NUMOD4 motif
IOCCKIGO_01713 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IOCCKIGO_01714 2.9e-260 yfnA E amino acid
IOCCKIGO_01715 1.3e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IOCCKIGO_01716 5e-90 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IOCCKIGO_01717 4.1e-40 ylqC S Belongs to the UPF0109 family
IOCCKIGO_01718 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IOCCKIGO_01719 3.9e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IOCCKIGO_01720 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IOCCKIGO_01721 1.8e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IOCCKIGO_01722 0.0 smc D Required for chromosome condensation and partitioning
IOCCKIGO_01723 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IOCCKIGO_01724 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IOCCKIGO_01725 3.7e-185 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IOCCKIGO_01726 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IOCCKIGO_01727 0.0 yloV S DAK2 domain fusion protein YloV
IOCCKIGO_01728 4.7e-58 asp S Asp23 family, cell envelope-related function
IOCCKIGO_01729 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IOCCKIGO_01730 4.8e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
IOCCKIGO_01731 3.6e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IOCCKIGO_01732 2.7e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IOCCKIGO_01733 0.0 KLT serine threonine protein kinase
IOCCKIGO_01734 8.5e-131 stp 3.1.3.16 T phosphatase
IOCCKIGO_01735 1.8e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IOCCKIGO_01736 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IOCCKIGO_01737 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IOCCKIGO_01738 1.2e-211 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IOCCKIGO_01739 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IOCCKIGO_01740 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IOCCKIGO_01741 1.4e-53
IOCCKIGO_01742 6.1e-262 recN L May be involved in recombinational repair of damaged DNA
IOCCKIGO_01743 2.5e-77 argR K Regulates arginine biosynthesis genes
IOCCKIGO_01744 5.3e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IOCCKIGO_01745 4.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IOCCKIGO_01746 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOCCKIGO_01747 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IOCCKIGO_01748 2.1e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IOCCKIGO_01749 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IOCCKIGO_01750 8.4e-70 yqhY S Asp23 family, cell envelope-related function
IOCCKIGO_01751 2e-110 J 2'-5' RNA ligase superfamily
IOCCKIGO_01752 1.4e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IOCCKIGO_01753 7.1e-127 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IOCCKIGO_01754 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IOCCKIGO_01755 3.7e-54 ysxB J Cysteine protease Prp
IOCCKIGO_01756 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
IOCCKIGO_01757 1.3e-111 K Transcriptional regulator
IOCCKIGO_01760 1.1e-86 dut S Protein conserved in bacteria
IOCCKIGO_01761 1.2e-172
IOCCKIGO_01762 5.2e-151
IOCCKIGO_01763 8.2e-51 S Iron-sulfur cluster assembly protein
IOCCKIGO_01764 3.6e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IOCCKIGO_01765 1.4e-153 P Belongs to the nlpA lipoprotein family
IOCCKIGO_01766 3.9e-12
IOCCKIGO_01767 1.1e-222 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IOCCKIGO_01768 1.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IOCCKIGO_01769 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
IOCCKIGO_01770 1.7e-176 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IOCCKIGO_01771 5.9e-22 S Protein of unknown function (DUF3042)
IOCCKIGO_01772 3.4e-67 yqhL P Rhodanese-like protein
IOCCKIGO_01773 1.5e-183 glk 2.7.1.2 G Glucokinase
IOCCKIGO_01774 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
IOCCKIGO_01775 2.7e-112 gluP 3.4.21.105 S Peptidase, S54 family
IOCCKIGO_01776 2.9e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IOCCKIGO_01777 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IOCCKIGO_01778 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IOCCKIGO_01779 0.0 S membrane
IOCCKIGO_01780 4.4e-70 yneR S Belongs to the HesB IscA family
IOCCKIGO_01781 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IOCCKIGO_01782 2.5e-118 udk 2.7.1.48 F Cytidine monophosphokinase
IOCCKIGO_01783 5.3e-113 rlpA M PFAM NLP P60 protein
IOCCKIGO_01784 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOCCKIGO_01785 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IOCCKIGO_01786 6.7e-59 yodB K Transcriptional regulator, HxlR family
IOCCKIGO_01787 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOCCKIGO_01788 4.8e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IOCCKIGO_01789 5e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IOCCKIGO_01790 1.3e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IOCCKIGO_01791 1.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IOCCKIGO_01792 6.3e-230 V MatE
IOCCKIGO_01793 1.8e-268 yjeM E Amino Acid
IOCCKIGO_01794 5.9e-277 arlS 2.7.13.3 T Histidine kinase
IOCCKIGO_01795 1.5e-121 K response regulator
IOCCKIGO_01796 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IOCCKIGO_01797 2.9e-99 yceD S Uncharacterized ACR, COG1399
IOCCKIGO_01798 1.6e-213 ylbM S Belongs to the UPF0348 family
IOCCKIGO_01799 3e-136 yqeM Q Methyltransferase
IOCCKIGO_01800 6.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IOCCKIGO_01801 3e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IOCCKIGO_01802 1.6e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IOCCKIGO_01803 1.9e-47 yhbY J RNA-binding protein
IOCCKIGO_01804 3.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
IOCCKIGO_01805 4.8e-96 yqeG S HAD phosphatase, family IIIA
IOCCKIGO_01806 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IOCCKIGO_01807 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IOCCKIGO_01808 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IOCCKIGO_01809 3.3e-172 dnaI L Primosomal protein DnaI
IOCCKIGO_01810 1.2e-226 dnaB L replication initiation and membrane attachment
IOCCKIGO_01811 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IOCCKIGO_01812 4.5e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IOCCKIGO_01813 1.2e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IOCCKIGO_01814 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IOCCKIGO_01815 1.4e-119 yoaK S Protein of unknown function (DUF1275)
IOCCKIGO_01816 4.6e-118 ybhL S Belongs to the BI1 family
IOCCKIGO_01817 1.2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IOCCKIGO_01818 9.4e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IOCCKIGO_01819 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IOCCKIGO_01820 7.5e-58 ytzB S Small secreted protein
IOCCKIGO_01821 3.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
IOCCKIGO_01822 1.6e-238 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IOCCKIGO_01823 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IOCCKIGO_01825 2e-29 S Acyltransferase family
IOCCKIGO_01826 7.1e-200 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IOCCKIGO_01827 2.3e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IOCCKIGO_01828 6e-160 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IOCCKIGO_01829 3.2e-118 argD 2.6.1.11, 2.6.1.17, 2.6.1.18, 2.6.1.36, 2.6.1.55, 2.6.1.62, 2.6.1.82 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IOCCKIGO_01833 1.3e-19 WQ51_00220 K Helix-turn-helix domain
IOCCKIGO_01834 1.2e-12 K Transcriptional
IOCCKIGO_01835 4.4e-90 L Integrase
IOCCKIGO_01836 7.1e-86 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IOCCKIGO_01837 4.5e-233 L Transposase IS66 family
IOCCKIGO_01838 2.3e-65 XK27_01125 L PFAM IS66 Orf2 family protein
IOCCKIGO_01840 6.5e-237 L Integrase core domain
IOCCKIGO_01841 5.8e-132 O Bacterial dnaA protein
IOCCKIGO_01842 6.6e-65 XK27_01125 L PFAM IS66 Orf2 family protein
IOCCKIGO_01843 1.3e-162 I alpha/beta hydrolase fold
IOCCKIGO_01844 4.2e-201 pbuG S permease
IOCCKIGO_01845 6.7e-26 L PFAM Integrase catalytic region
IOCCKIGO_01846 1.1e-104 yocS S SBF-like CPA transporter family (DUF4137)
IOCCKIGO_01847 3.7e-130 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IOCCKIGO_01848 7.1e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IOCCKIGO_01849 1.2e-230 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IOCCKIGO_01850 1.9e-206 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IOCCKIGO_01851 1.3e-205 ydiN G Major Facilitator Superfamily
IOCCKIGO_01852 1.4e-155 menH 2.2.1.9, 4.2.99.20, 6.2.1.26 I Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IOCCKIGO_01853 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IOCCKIGO_01854 9.6e-250 menF 5.4.4.2 HQ chorismate binding enzyme
IOCCKIGO_01855 1.6e-65 S Uncharacterised protein family (UPF0236)
IOCCKIGO_01856 8e-53 yhaI S Protein of unknown function (DUF805)
IOCCKIGO_01857 6.5e-44
IOCCKIGO_01858 2.4e-22
IOCCKIGO_01859 5.4e-47
IOCCKIGO_01860 3.2e-95 K Acetyltransferase (GNAT) domain
IOCCKIGO_01861 4.5e-296 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IOCCKIGO_01862 7.1e-229 gntT EG Gluconate
IOCCKIGO_01863 2.6e-183 K Transcriptional regulator, LacI family
IOCCKIGO_01864 5.9e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IOCCKIGO_01865 8.5e-96
IOCCKIGO_01866 2.3e-24
IOCCKIGO_01867 3.7e-61 asp S Asp23 family, cell envelope-related function
IOCCKIGO_01868 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IOCCKIGO_01870 7.1e-50
IOCCKIGO_01871 1.1e-68 yqkB S Belongs to the HesB IscA family
IOCCKIGO_01872 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
IOCCKIGO_01873 1.9e-83 F Hydrolase, NUDIX family
IOCCKIGO_01874 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOCCKIGO_01875 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IOCCKIGO_01876 9.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IOCCKIGO_01877 2.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
IOCCKIGO_01878 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IOCCKIGO_01879 6.4e-162 dprA LU DNA protecting protein DprA
IOCCKIGO_01880 9.4e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IOCCKIGO_01881 9.2e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IOCCKIGO_01882 4.4e-35 yozE S Belongs to the UPF0346 family
IOCCKIGO_01883 8.2e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IOCCKIGO_01884 4e-170 ypmR E lipolytic protein G-D-S-L family
IOCCKIGO_01885 2.2e-151 DegV S EDD domain protein, DegV family
IOCCKIGO_01886 5e-111 hlyIII S protein, hemolysin III
IOCCKIGO_01887 9.3e-86 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IOCCKIGO_01888 3.6e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IOCCKIGO_01889 0.0 yfmR S ABC transporter, ATP-binding protein
IOCCKIGO_01890 4.8e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IOCCKIGO_01891 2.8e-235 S Tetratricopeptide repeat protein
IOCCKIGO_01892 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IOCCKIGO_01893 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IOCCKIGO_01894 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
IOCCKIGO_01895 7.9e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IOCCKIGO_01896 2.5e-13 M Lysin motif
IOCCKIGO_01897 2.8e-263 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IOCCKIGO_01898 1.4e-187 ypbB 5.1.3.1 S Helix-turn-helix domain
IOCCKIGO_01899 7.6e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IOCCKIGO_01900 9e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IOCCKIGO_01901 8.5e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IOCCKIGO_01902 1.4e-139 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IOCCKIGO_01903 4.3e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IOCCKIGO_01904 1.7e-162 xerD D recombinase XerD
IOCCKIGO_01905 7.9e-168 cvfB S S1 domain
IOCCKIGO_01906 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IOCCKIGO_01907 0.0 dnaE 2.7.7.7 L DNA polymerase
IOCCKIGO_01908 3e-30 S Protein of unknown function (DUF2929)
IOCCKIGO_01909 2.2e-151 lysA2 M Glycosyl hydrolases family 25
IOCCKIGO_01910 4.4e-34 S Bacteriophage holin of superfamily 6 (Holin_LLH)
IOCCKIGO_01917 1.8e-43 GT2,GT4 LM gp58-like protein
IOCCKIGO_01918 9.8e-145 ydhO 3.4.14.13 M Prophage endopeptidase tail
IOCCKIGO_01919 8.3e-85 S Phage tail protein
IOCCKIGO_01920 1.6e-219 M Phage tail tape measure protein TP901
IOCCKIGO_01922 9.1e-14 S Phage tail assembly chaperone proteins, TAC
IOCCKIGO_01923 4.6e-77 S Phage tail tube protein
IOCCKIGO_01924 1.5e-19 S Protein of unknown function (DUF806)
IOCCKIGO_01925 6.4e-38 S exonuclease activity
IOCCKIGO_01926 6.4e-10 S Phage head-tail joining protein
IOCCKIGO_01927 6e-50 S Phage gp6-like head-tail connector protein
IOCCKIGO_01928 7.7e-179 S Phage capsid family
IOCCKIGO_01929 7e-106 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
IOCCKIGO_01930 1.8e-199 S Phage portal protein
IOCCKIGO_01932 7.8e-290 S overlaps another CDS with the same product name
IOCCKIGO_01933 7.7e-66 L Phage terminase, small subunit
IOCCKIGO_01934 4.4e-59 L HNH nucleases
IOCCKIGO_01936 1.6e-20
IOCCKIGO_01941 4.8e-114 frnE Q DSBA-like thioredoxin domain
IOCCKIGO_01942 1.4e-54
IOCCKIGO_01943 5.9e-48 L PFAM transposase IS200-family protein
IOCCKIGO_01944 2.4e-56 yitW S Pfam:DUF59
IOCCKIGO_01945 2.9e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IOCCKIGO_01946 2.1e-63 IQ Enoyl-(Acyl carrier protein) reductase
IOCCKIGO_01948 2e-100 S Membrane protein involved in the export of O-antigen and teichoic acid
IOCCKIGO_01949 1.7e-78 S Uncharacterised protein family (UPF0236)
IOCCKIGO_01950 3.2e-104 S Uncharacterised protein family (UPF0236)
IOCCKIGO_01951 9.2e-256 S Uncharacterised protein family (UPF0236)
IOCCKIGO_01952 2.4e-76 L Helix-turn-helix domain
IOCCKIGO_01953 1.5e-139 L hmm pf00665
IOCCKIGO_01954 1.9e-104 L Belongs to the 'phage' integrase family
IOCCKIGO_01955 7.5e-155 glcU U sugar transport
IOCCKIGO_01956 9.4e-149 E Glyoxalase-like domain
IOCCKIGO_01957 6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IOCCKIGO_01958 2e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IOCCKIGO_01959 4.4e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IOCCKIGO_01960 4.4e-129 V ABC transporter
IOCCKIGO_01961 2.6e-217 bacI V MacB-like periplasmic core domain
IOCCKIGO_01963 1.3e-37
IOCCKIGO_01964 2.9e-257 S Putative peptidoglycan binding domain
IOCCKIGO_01967 4.6e-188 2.7.13.3 T GHKL domain
IOCCKIGO_01968 3.7e-129 K LytTr DNA-binding domain
IOCCKIGO_01972 1.9e-244 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IOCCKIGO_01974 8.5e-75 osmC O OsmC-like protein
IOCCKIGO_01975 7.3e-178 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IOCCKIGO_01976 8.9e-215 patA 2.6.1.1 E Aminotransferase
IOCCKIGO_01977 2.7e-32
IOCCKIGO_01978 0.0 clpL O associated with various cellular activities
IOCCKIGO_01979 2.7e-165 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IOCCKIGO_01981 1.7e-105 wecD3 K PFAM GCN5-related N-acetyltransferase
IOCCKIGO_01982 7.9e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IOCCKIGO_01983 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IOCCKIGO_01984 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IOCCKIGO_01985 4.3e-172 malR K Transcriptional regulator, LacI family
IOCCKIGO_01986 2.6e-211 phbA 2.3.1.9 I Belongs to the thiolase family
IOCCKIGO_01987 1.1e-256 malT G Major Facilitator
IOCCKIGO_01988 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IOCCKIGO_01989 2.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IOCCKIGO_01990 3.6e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IOCCKIGO_01991 7.8e-137 puuD S peptidase C26
IOCCKIGO_01992 5.9e-168 yvgN C Aldo keto reductase
IOCCKIGO_01993 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
IOCCKIGO_01994 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
IOCCKIGO_01995 2.3e-87 hmpT S ECF-type riboflavin transporter, S component
IOCCKIGO_01996 1.1e-261 nox C NADH oxidase
IOCCKIGO_01997 3.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IOCCKIGO_01998 1.5e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IOCCKIGO_01999 3.6e-87
IOCCKIGO_02000 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IOCCKIGO_02002 6.6e-136 puuD S peptidase C26
IOCCKIGO_02003 9.3e-248 steT_1 E amino acid
IOCCKIGO_02004 6.7e-108 K Transcriptional regulator, TetR family
IOCCKIGO_02005 7e-71
IOCCKIGO_02006 8.7e-263 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IOCCKIGO_02007 8.5e-263 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
IOCCKIGO_02008 4.6e-269 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
IOCCKIGO_02009 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IOCCKIGO_02010 4e-267 G Major Facilitator
IOCCKIGO_02011 1e-259 G Major Facilitator
IOCCKIGO_02012 3.4e-183 K Transcriptional regulator, LacI family
IOCCKIGO_02013 5.9e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IOCCKIGO_02015 5.4e-101 nqr 1.5.1.36 S reductase
IOCCKIGO_02016 1.5e-196 XK27_09615 S reductase
IOCCKIGO_02017 1.3e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IOCCKIGO_02018 5.4e-71 L hmm pf00665
IOCCKIGO_02019 1.3e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IOCCKIGO_02020 2.2e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
IOCCKIGO_02021 4.4e-66 S Glycosyltransferase like family
IOCCKIGO_02022 9e-77 rgpB GT2 M Glycosyl transferase family 2
IOCCKIGO_02023 8.7e-28 M biosynthesis protein
IOCCKIGO_02024 7.7e-89 cps3F
IOCCKIGO_02025 2.3e-75 M transferase activity, transferring glycosyl groups
IOCCKIGO_02026 3.9e-209 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
IOCCKIGO_02027 1.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
IOCCKIGO_02028 1.8e-24
IOCCKIGO_02029 0.0 G Peptidase_C39 like family
IOCCKIGO_02030 0.0 2.7.7.6 M Peptidase family M23
IOCCKIGO_02031 4.2e-118 rfbP 2.7.8.6 M Bacterial sugar transferase
IOCCKIGO_02032 3.9e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IOCCKIGO_02033 1.3e-145 cps1D M Domain of unknown function (DUF4422)
IOCCKIGO_02034 3e-134 recX 2.4.1.337 GT4 S Regulatory protein RecX
IOCCKIGO_02035 4.9e-31
IOCCKIGO_02036 9.5e-33 S Protein of unknown function (DUF2922)
IOCCKIGO_02037 5.8e-150 yihY S Belongs to the UPF0761 family
IOCCKIGO_02038 9e-281 yjeM E Amino Acid
IOCCKIGO_02039 7.3e-256 E Arginine ornithine antiporter
IOCCKIGO_02040 1.7e-220 arcT 2.6.1.1 E Aminotransferase
IOCCKIGO_02041 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
IOCCKIGO_02042 6.1e-79 fld C Flavodoxin
IOCCKIGO_02043 1.5e-74 gtcA S Teichoic acid glycosylation protein
IOCCKIGO_02044 9.3e-56
IOCCKIGO_02045 1.1e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IOCCKIGO_02047 1.4e-226 yfmL L DEAD DEAH box helicase
IOCCKIGO_02048 5e-190 mocA S Oxidoreductase
IOCCKIGO_02049 9.1e-62 S Domain of unknown function (DUF4828)
IOCCKIGO_02050 5.8e-103 yvdD 3.2.2.10 S Belongs to the LOG family
IOCCKIGO_02051 7.7e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IOCCKIGO_02052 4.2e-294 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IOCCKIGO_02053 1.2e-191 S Protein of unknown function (DUF3114)
IOCCKIGO_02054 3.3e-77 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
IOCCKIGO_02055 8.4e-120 ybhL S Belongs to the BI1 family
IOCCKIGO_02056 5.5e-21
IOCCKIGO_02057 1.8e-72 K LytTr DNA-binding domain
IOCCKIGO_02058 1e-67 S Protein of unknown function (DUF3021)
IOCCKIGO_02059 1.1e-138 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
IOCCKIGO_02060 1.6e-30 XK27_00915 C Luciferase-like monooxygenase
IOCCKIGO_02061 1.1e-118 pnb C nitroreductase
IOCCKIGO_02062 7.6e-89
IOCCKIGO_02063 1.2e-241 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
IOCCKIGO_02064 5.2e-92 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IOCCKIGO_02066 1.6e-46
IOCCKIGO_02067 5.7e-155 cylA V ABC transporter
IOCCKIGO_02068 1.8e-145 cylB V ABC-2 type transporter
IOCCKIGO_02069 1.3e-73 K LytTr DNA-binding domain
IOCCKIGO_02070 1.2e-59 S Protein of unknown function (DUF3021)
IOCCKIGO_02072 8.5e-176 L Plasmid pRiA4b ORF-3-like protein
IOCCKIGO_02075 9e-71 padR K Transcriptional regulator PadR-like family
IOCCKIGO_02076 1.4e-245 norB EGP Major Facilitator
IOCCKIGO_02077 2.8e-105 1.6.5.2 S NADPH-dependent FMN reductase
IOCCKIGO_02078 3.1e-53 K Bacterial regulatory proteins, tetR family
IOCCKIGO_02079 4.5e-47 V ABC transporter, ATP-binding protein
IOCCKIGO_02080 7.1e-29 V ABC transporter, ATP-binding protein
IOCCKIGO_02081 5.8e-54 yqkB S Belongs to the HesB IscA family
IOCCKIGO_02082 2.9e-20
IOCCKIGO_02083 2e-19
IOCCKIGO_02084 1.9e-15 K LytTr DNA-binding domain
IOCCKIGO_02085 3.1e-58
IOCCKIGO_02086 5.8e-74 S Metallo-beta-lactamase superfamily
IOCCKIGO_02087 9.3e-31 K Psort location Cytoplasmic, score
IOCCKIGO_02088 5.3e-23 K Psort location Cytoplasmic, score
IOCCKIGO_02089 3.8e-51 yjdF S Protein of unknown function (DUF2992)
IOCCKIGO_02090 2.3e-105 L Transposase
IOCCKIGO_02091 3e-96 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IOCCKIGO_02092 8.5e-39 L Integrase core domain
IOCCKIGO_02093 4.2e-37 mrr L restriction endonuclease
IOCCKIGO_02094 0.0 L PLD-like domain
IOCCKIGO_02096 3.1e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IOCCKIGO_02097 9.4e-192 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IOCCKIGO_02098 2.5e-96 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
IOCCKIGO_02099 1.2e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IOCCKIGO_02100 4.4e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IOCCKIGO_02101 1.9e-103 T Ion transport 2 domain protein
IOCCKIGO_02102 0.0 S Bacterial membrane protein YfhO
IOCCKIGO_02103 8.3e-205 G Transporter, major facilitator family protein
IOCCKIGO_02104 1.6e-108 yvrI K RNA polymerase sigma factor, sigma-70 family
IOCCKIGO_02105 1.2e-64 ydiI Q Thioesterase superfamily
IOCCKIGO_02106 1.9e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IOCCKIGO_02107 5.7e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IOCCKIGO_02108 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IOCCKIGO_02109 4.2e-32 feoA P FeoA domain
IOCCKIGO_02110 6.5e-145 sufC O FeS assembly ATPase SufC
IOCCKIGO_02111 3.9e-240 sufD O FeS assembly protein SufD
IOCCKIGO_02112 3.3e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IOCCKIGO_02113 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
IOCCKIGO_02114 3e-270 sufB O assembly protein SufB
IOCCKIGO_02115 2.4e-56 yitW S Iron-sulfur cluster assembly protein
IOCCKIGO_02116 1.4e-159 hipB K Helix-turn-helix
IOCCKIGO_02117 1.6e-112 nreC K PFAM regulatory protein LuxR
IOCCKIGO_02118 9.2e-39 S Cytochrome B5
IOCCKIGO_02119 1.2e-154 yitU 3.1.3.104 S hydrolase
IOCCKIGO_02120 7.7e-263 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IOCCKIGO_02121 1.8e-148 f42a O Band 7 protein
IOCCKIGO_02122 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
IOCCKIGO_02123 1.4e-130 lytT K response regulator receiver
IOCCKIGO_02124 1.9e-66 lrgA S LrgA family
IOCCKIGO_02125 1.3e-123 lrgB M LrgB-like family
IOCCKIGO_02126 3.2e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IOCCKIGO_02127 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IOCCKIGO_02128 9.7e-186 galR K Periplasmic binding protein-like domain
IOCCKIGO_02129 0.0 rafA 3.2.1.22 G alpha-galactosidase
IOCCKIGO_02130 4.9e-87 S Protein of unknown function (DUF1440)
IOCCKIGO_02131 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IOCCKIGO_02132 4.6e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IOCCKIGO_02133 4e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IOCCKIGO_02134 1.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IOCCKIGO_02135 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IOCCKIGO_02136 4e-87 ypmB S Protein conserved in bacteria
IOCCKIGO_02137 2.8e-123 dnaD L DnaD domain protein
IOCCKIGO_02138 7.4e-161 EG EamA-like transporter family
IOCCKIGO_02139 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IOCCKIGO_02140 3.7e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IOCCKIGO_02141 2.6e-103 ypsA S Belongs to the UPF0398 family
IOCCKIGO_02142 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IOCCKIGO_02143 1.1e-83 F Belongs to the NrdI family
IOCCKIGO_02144 5e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IOCCKIGO_02145 4e-71 rnhA 3.1.26.4 L Ribonuclease HI
IOCCKIGO_02146 5.6e-65 esbA S Family of unknown function (DUF5322)
IOCCKIGO_02147 2e-71 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IOCCKIGO_02148 3.8e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IOCCKIGO_02149 1.1e-206 carA 6.3.5.5 F Belongs to the CarA family
IOCCKIGO_02150 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IOCCKIGO_02151 0.0 FbpA K Fibronectin-binding protein
IOCCKIGO_02152 6.4e-162 degV S EDD domain protein, DegV family
IOCCKIGO_02153 9.4e-94
IOCCKIGO_02154 8.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IOCCKIGO_02155 3.9e-136 gspA M family 8
IOCCKIGO_02156 1.2e-160 S Alpha beta hydrolase
IOCCKIGO_02157 1.8e-95 K Acetyltransferase (GNAT) domain
IOCCKIGO_02158 8.9e-108 XK27_08635 S UPF0210 protein
IOCCKIGO_02159 4.1e-50 XK27_08635 S UPF0210 protein
IOCCKIGO_02160 3e-38 gcvR T Belongs to the UPF0237 family
IOCCKIGO_02161 9.7e-166 1.1.1.346 C Aldo keto reductase
IOCCKIGO_02162 4.2e-42 K Transcriptional regulator
IOCCKIGO_02163 5.5e-22

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)