ORF_ID e_value Gene_name EC_number CAZy COGs Description
HGHHNEPF_00002 2.5e-232 S Putative peptidoglycan binding domain
HGHHNEPF_00003 5.3e-52 M NlpC P60 family protein
HGHHNEPF_00004 1.2e-35
HGHHNEPF_00006 3e-213 bacI V MacB-like periplasmic core domain
HGHHNEPF_00007 9.8e-129 V ABC transporter
HGHHNEPF_00008 4.4e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGHHNEPF_00009 5.2e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HGHHNEPF_00010 7.8e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGHHNEPF_00011 9.4e-149 E Glyoxalase-like domain
HGHHNEPF_00012 7.5e-155 glcU U sugar transport
HGHHNEPF_00013 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HGHHNEPF_00014 2.2e-96 S reductase
HGHHNEPF_00015 1.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HGHHNEPF_00016 2.7e-17 ABC-SBP S ABC transporter
HGHHNEPF_00017 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HGHHNEPF_00018 1.9e-218 htrA 3.4.21.107 O serine protease
HGHHNEPF_00019 2.3e-153 vicX 3.1.26.11 S domain protein
HGHHNEPF_00020 5.4e-150 yycI S YycH protein
HGHHNEPF_00021 1.5e-247 yycH S YycH protein
HGHHNEPF_00022 0.0 vicK 2.7.13.3 T Histidine kinase
HGHHNEPF_00023 5.2e-130 K response regulator
HGHHNEPF_00025 3.4e-308 lmrA 3.6.3.44 V ABC transporter
HGHHNEPF_00026 2.3e-72 K helix_turn_helix multiple antibiotic resistance protein
HGHHNEPF_00028 5.7e-122 Z012_01130 S Fic/DOC family
HGHHNEPF_00029 1.1e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HGHHNEPF_00030 4.8e-54
HGHHNEPF_00031 2.2e-205 yttB EGP Major facilitator Superfamily
HGHHNEPF_00032 6.9e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HGHHNEPF_00033 7.6e-74 rplI J Binds to the 23S rRNA
HGHHNEPF_00034 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HGHHNEPF_00035 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGHHNEPF_00036 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HGHHNEPF_00037 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HGHHNEPF_00038 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGHHNEPF_00039 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGHHNEPF_00040 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGHHNEPF_00041 6.4e-34 yaaA S S4 domain protein YaaA
HGHHNEPF_00042 2.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HGHHNEPF_00043 1.9e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGHHNEPF_00044 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HGHHNEPF_00045 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HGHHNEPF_00046 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGHHNEPF_00047 9.7e-130 jag S R3H domain protein
HGHHNEPF_00048 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGHHNEPF_00049 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HGHHNEPF_00050 0.0 asnB 6.3.5.4 E Asparagine synthase
HGHHNEPF_00051 2.4e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGHHNEPF_00052 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
HGHHNEPF_00053 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HGHHNEPF_00054 1.6e-88 2.3.1.183 M Acetyltransferase GNAT family
HGHHNEPF_00055 2.3e-159 S reductase
HGHHNEPF_00057 1.9e-07 yiiE S Psort location CytoplasmicMembrane, score 10.00
HGHHNEPF_00059 7.5e-57 K LysR substrate binding domain
HGHHNEPF_00060 7.7e-299 S amidohydrolase
HGHHNEPF_00062 4e-36 blpT
HGHHNEPF_00063 6.5e-45 K LytTr DNA-binding domain
HGHHNEPF_00064 1.9e-24 plnB 2.7.13.3 T GHKL domain
HGHHNEPF_00066 1.6e-105 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HGHHNEPF_00067 2.6e-112 L Helix-turn-helix domain
HGHHNEPF_00068 1.6e-120 L hmm pf00665
HGHHNEPF_00069 5.6e-98 ywlG S Belongs to the UPF0340 family
HGHHNEPF_00070 4.3e-198 EGP Major facilitator Superfamily
HGHHNEPF_00071 2.8e-111 M Lysin motif
HGHHNEPF_00072 1.6e-79
HGHHNEPF_00073 9.6e-62 P CorA-like Mg2+ transporter protein
HGHHNEPF_00074 5.6e-77 P CorA-like Mg2+ transporter protein
HGHHNEPF_00075 5.6e-97 wecD3 K PFAM GCN5-related N-acetyltransferase
HGHHNEPF_00076 1.1e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HGHHNEPF_00077 4.3e-13
HGHHNEPF_00078 5.5e-77 S Domain of unknown function (DUF4767)
HGHHNEPF_00079 9.7e-197 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HGHHNEPF_00080 1.3e-113 S Membrane
HGHHNEPF_00081 3.9e-122 O Zinc-dependent metalloprotease
HGHHNEPF_00082 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HGHHNEPF_00083 2.3e-159 metQ_4 P Belongs to the nlpA lipoprotein family
HGHHNEPF_00085 0.0 UW LPXTG-motif cell wall anchor domain protein
HGHHNEPF_00086 0.0 UW LPXTG-motif cell wall anchor domain protein
HGHHNEPF_00087 0.0 UW LPXTG-motif cell wall anchor domain protein
HGHHNEPF_00088 4.9e-183 S Phosphotransferase system, EIIC
HGHHNEPF_00089 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGHHNEPF_00090 2.8e-60
HGHHNEPF_00091 2.1e-95
HGHHNEPF_00093 3.5e-15 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGHHNEPF_00094 6.6e-23 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGHHNEPF_00095 3.7e-96 2.3.1.128 K acetyltransferase
HGHHNEPF_00096 1.6e-167
HGHHNEPF_00097 1.2e-14 K Transcriptional regulator, HxlR family
HGHHNEPF_00098 2.1e-216 P ammonium transporter
HGHHNEPF_00099 4.4e-94 ureI S AmiS/UreI family transporter
HGHHNEPF_00100 2.9e-45 ureA 3.5.1.5 E Urease, gamma subunit
HGHHNEPF_00101 7.7e-64 ureB 3.5.1.5 E Urease beta subunit
HGHHNEPF_00102 0.0 ureC 3.5.1.5 E Amidohydrolase family
HGHHNEPF_00103 3.3e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HGHHNEPF_00104 6.9e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HGHHNEPF_00105 2.1e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HGHHNEPF_00106 2.4e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HGHHNEPF_00107 5.5e-41 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGHHNEPF_00108 1.3e-72 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGHHNEPF_00109 1e-182 nikMN P PDGLE domain
HGHHNEPF_00110 2.1e-133 P Cobalt transport protein
HGHHNEPF_00111 8.6e-136 cbiO P ABC transporter
HGHHNEPF_00112 6.6e-133 K Transcriptional regulatory protein, C-terminal domain protein
HGHHNEPF_00113 9.6e-158 pstS P Phosphate
HGHHNEPF_00114 4.7e-152 pstC P probably responsible for the translocation of the substrate across the membrane
HGHHNEPF_00115 3.2e-153 pstA P Phosphate transport system permease protein PstA
HGHHNEPF_00116 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGHHNEPF_00117 2.1e-123 phoU P Plays a role in the regulation of phosphate uptake
HGHHNEPF_00118 3.4e-81 S ECF transporter, substrate-specific component
HGHHNEPF_00119 9.6e-62 S Domain of unknown function (DUF4430)
HGHHNEPF_00120 2.2e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HGHHNEPF_00121 5.3e-130 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HGHHNEPF_00122 7e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
HGHHNEPF_00123 9.9e-135 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HGHHNEPF_00124 7.8e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
HGHHNEPF_00125 1.4e-250 hemL 5.4.3.8 H Aminotransferase class-III
HGHHNEPF_00126 3.8e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
HGHHNEPF_00127 2.9e-165 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HGHHNEPF_00128 4.4e-228 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HGHHNEPF_00129 6.7e-78 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
HGHHNEPF_00130 1.8e-276 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HGHHNEPF_00131 2.8e-148 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
HGHHNEPF_00132 4.4e-118 cbiQ P Cobalt transport protein
HGHHNEPF_00133 8.7e-53 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HGHHNEPF_00134 5.3e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HGHHNEPF_00135 2.1e-123 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HGHHNEPF_00136 1.8e-144 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
HGHHNEPF_00137 1.3e-257 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HGHHNEPF_00138 6.4e-134 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
HGHHNEPF_00139 1.8e-130 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HGHHNEPF_00140 5.5e-192 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
HGHHNEPF_00141 1.2e-132 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HGHHNEPF_00142 1.7e-96 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HGHHNEPF_00143 9.7e-109 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HGHHNEPF_00144 1.5e-206 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HGHHNEPF_00145 2.7e-123 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
HGHHNEPF_00146 1.7e-179 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HGHHNEPF_00147 1.5e-261 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HGHHNEPF_00148 3.7e-207 cobD 4.1.1.81 E Aminotransferase class I and II
HGHHNEPF_00149 6.3e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
HGHHNEPF_00150 7.3e-155 XK27_04590 S NADPH-dependent FMN reductase
HGHHNEPF_00151 3.9e-78 fld C Flavodoxin
HGHHNEPF_00152 8.8e-72 eutP E Ethanolamine utilisation - propanediol utilisation
HGHHNEPF_00153 6.7e-80 P Cadmium resistance transporter
HGHHNEPF_00154 1.3e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
HGHHNEPF_00155 1.4e-147 3.1.3.48 T Pfam:Y_phosphatase3C
HGHHNEPF_00156 5.5e-56 pduU E BMC
HGHHNEPF_00157 1.4e-220 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGHHNEPF_00158 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
HGHHNEPF_00159 3.1e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HGHHNEPF_00160 7.4e-80 pduO S Haem-degrading
HGHHNEPF_00161 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HGHHNEPF_00162 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HGHHNEPF_00163 6.4e-90 S Putative propanediol utilisation
HGHHNEPF_00164 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HGHHNEPF_00165 4.9e-42 pduA_4 CQ BMC
HGHHNEPF_00166 1.4e-72 pduK CQ BMC
HGHHNEPF_00167 2.5e-59 pduH S Dehydratase medium subunit
HGHHNEPF_00168 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
HGHHNEPF_00169 3.7e-77 pduE 4.2.1.28 Q Dehydratase small subunit
HGHHNEPF_00170 4.2e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HGHHNEPF_00171 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HGHHNEPF_00172 2.7e-134 pduB E BMC
HGHHNEPF_00173 6.2e-42 pduA_4 CQ BMC
HGHHNEPF_00174 3.4e-197 K helix_turn_helix, arabinose operon control protein
HGHHNEPF_00175 7.8e-149 eutJ E Hsp70 protein
HGHHNEPF_00176 1.2e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HGHHNEPF_00177 2.1e-163
HGHHNEPF_00178 2.4e-158 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HGHHNEPF_00179 8.7e-172 S AI-2E family transporter
HGHHNEPF_00180 8.9e-133 XK27_07210 6.1.1.6 S B3 4 domain
HGHHNEPF_00181 2.5e-77 yybA 2.3.1.57 K Transcriptional regulator
HGHHNEPF_00182 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
HGHHNEPF_00183 1.8e-90 GM epimerase
HGHHNEPF_00184 6.3e-154 ypdB V (ABC) transporter
HGHHNEPF_00185 1.6e-241 yhdP S Transporter associated domain
HGHHNEPF_00186 1.3e-84 nrdI F Belongs to the NrdI family
HGHHNEPF_00187 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
HGHHNEPF_00188 9.8e-192 yeaN P Transporter, major facilitator family protein
HGHHNEPF_00189 2.9e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGHHNEPF_00190 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGHHNEPF_00191 2e-33
HGHHNEPF_00192 0.0 lacS G Transporter
HGHHNEPF_00193 1.5e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HGHHNEPF_00194 8.5e-87
HGHHNEPF_00195 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HGHHNEPF_00196 8.3e-205 yttB EGP Major facilitator Superfamily
HGHHNEPF_00197 1.6e-106
HGHHNEPF_00198 1e-24
HGHHNEPF_00199 1.3e-171 scrR K Transcriptional regulator, LacI family
HGHHNEPF_00200 1e-240 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGHHNEPF_00201 4.1e-50 czrA K Transcriptional regulator, ArsR family
HGHHNEPF_00202 1.3e-37
HGHHNEPF_00203 0.0 yhcA V ABC transporter, ATP-binding protein
HGHHNEPF_00204 6.7e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HGHHNEPF_00205 5.4e-171 hrtB V ABC transporter permease
HGHHNEPF_00206 4.4e-86 ygfC K transcriptional regulator (TetR family)
HGHHNEPF_00207 1.7e-190 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HGHHNEPF_00208 3e-290 mntH P H( )-stimulated, divalent metal cation uptake system
HGHHNEPF_00209 1.6e-22
HGHHNEPF_00210 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGHHNEPF_00212 2.3e-32 yxiO S Vacuole effluxer Atg22 like
HGHHNEPF_00213 2.3e-117 yxiO S Vacuole effluxer Atg22 like
HGHHNEPF_00214 8.1e-20 yxiO S Vacuole effluxer Atg22 like
HGHHNEPF_00215 2.9e-251 npp S type I phosphodiesterase nucleotide pyrophosphatase
HGHHNEPF_00216 4.1e-240 E amino acid
HGHHNEPF_00217 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGHHNEPF_00218 8.8e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
HGHHNEPF_00219 1.7e-40 S Cytochrome B5
HGHHNEPF_00220 5.4e-09 S Cytochrome B5
HGHHNEPF_00221 2.7e-38 S Cytochrome B5
HGHHNEPF_00222 3.6e-73 elaA S Gnat family
HGHHNEPF_00223 3e-10 GM NmrA-like family
HGHHNEPF_00224 8.1e-51 hxlR K Transcriptional regulator, HxlR family
HGHHNEPF_00225 4.5e-106 XK27_02070 S Nitroreductase family
HGHHNEPF_00226 7.1e-80 K Transcriptional regulator, HxlR family
HGHHNEPF_00227 1.7e-227
HGHHNEPF_00228 1.3e-205 EGP Major facilitator Superfamily
HGHHNEPF_00229 5.4e-253 pepC 3.4.22.40 E aminopeptidase
HGHHNEPF_00230 3.4e-112 ylbE GM NAD dependent epimerase dehydratase family protein
HGHHNEPF_00231 0.0 pepN 3.4.11.2 E aminopeptidase
HGHHNEPF_00232 1.3e-88 folT S ECF transporter, substrate-specific component
HGHHNEPF_00233 1.3e-29 yjaB_1 K Acetyltransferase (GNAT) domain
HGHHNEPF_00234 1.4e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
HGHHNEPF_00235 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HGHHNEPF_00236 1.4e-17
HGHHNEPF_00237 5e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
HGHHNEPF_00238 2.4e-62 yneR
HGHHNEPF_00239 9.6e-158 akr5f 1.1.1.346 S reductase
HGHHNEPF_00240 7.8e-152 K Transcriptional regulator
HGHHNEPF_00241 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HGHHNEPF_00242 1.4e-165 ypuA S Protein of unknown function (DUF1002)
HGHHNEPF_00243 3.5e-56 padR K Virulence activator alpha C-term
HGHHNEPF_00244 7.5e-92 padC Q Phenolic acid decarboxylase
HGHHNEPF_00245 7.4e-71 C Flavodoxin
HGHHNEPF_00246 4.1e-110 S Oxidoreductase, aldo keto reductase family protein
HGHHNEPF_00247 1.3e-31 S Oxidoreductase, aldo keto reductase family protein
HGHHNEPF_00248 2.8e-54 yphJ 4.1.1.44 S decarboxylase
HGHHNEPF_00249 2.4e-10 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HGHHNEPF_00250 1.8e-115 P nitric oxide dioxygenase activity
HGHHNEPF_00251 3e-108 S Peptidase propeptide and YPEB domain
HGHHNEPF_00252 1.5e-239 T GHKL domain
HGHHNEPF_00253 1e-122 T Transcriptional regulatory protein, C terminal
HGHHNEPF_00254 2.1e-43 mleP3 S Membrane transport protein
HGHHNEPF_00256 2.8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
HGHHNEPF_00257 3.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HGHHNEPF_00258 1.5e-112 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HGHHNEPF_00259 1.7e-249 yagE E amino acid
HGHHNEPF_00260 2.9e-84 dps P Belongs to the Dps family
HGHHNEPF_00261 0.0 pacL 3.6.3.8 P P-type ATPase
HGHHNEPF_00262 3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HGHHNEPF_00263 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HGHHNEPF_00264 2.2e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HGHHNEPF_00265 4.5e-146 potB P ABC transporter permease
HGHHNEPF_00266 7.1e-139 potC P ABC transporter permease
HGHHNEPF_00267 2.5e-208 potD P ABC transporter
HGHHNEPF_00268 1.3e-230
HGHHNEPF_00269 1.1e-234 EGP Sugar (and other) transporter
HGHHNEPF_00270 1.3e-254 yfnA E Amino Acid
HGHHNEPF_00271 2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HGHHNEPF_00272 3.2e-98 gmk2 2.7.4.8 F Guanylate kinase
HGHHNEPF_00273 1.5e-82 zur P Belongs to the Fur family
HGHHNEPF_00274 3.1e-17 3.2.1.14 GH18
HGHHNEPF_00275 5.4e-150
HGHHNEPF_00276 8.3e-38 pspC KT PspC domain protein
HGHHNEPF_00277 1.6e-94 K Transcriptional regulator (TetR family)
HGHHNEPF_00278 1.9e-234 V domain protein
HGHHNEPF_00279 5.1e-179 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHHNEPF_00281 6.6e-35 S Transglycosylase associated protein
HGHHNEPF_00282 1.6e-233 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGHHNEPF_00283 1.9e-126 G phosphoglycerate mutase
HGHHNEPF_00284 1.2e-115 dedA S SNARE associated Golgi protein
HGHHNEPF_00285 0.0 helD 3.6.4.12 L DNA helicase
HGHHNEPF_00286 7.9e-244 nox C NADH oxidase
HGHHNEPF_00287 2.9e-254 nox C NADH oxidase
HGHHNEPF_00288 2.5e-158 EG EamA-like transporter family
HGHHNEPF_00289 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HGHHNEPF_00290 1.3e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HGHHNEPF_00291 3e-223 S cog cog1373
HGHHNEPF_00293 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HGHHNEPF_00295 2.3e-163 sthIM 2.1.1.72 L DNA methylase
HGHHNEPF_00296 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
HGHHNEPF_00297 1.1e-218 oxlT P Major Facilitator Superfamily
HGHHNEPF_00298 6.2e-157 spoU 2.1.1.185 J Methyltransferase
HGHHNEPF_00299 2.1e-37 rmeB K transcriptional regulator, MerR family
HGHHNEPF_00300 7.2e-08 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HGHHNEPF_00301 9.8e-27 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HGHHNEPF_00302 1.5e-99 crp_2 K Cyclic nucleotide-binding domain
HGHHNEPF_00303 3.3e-127 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
HGHHNEPF_00304 1.2e-137 pnuC H nicotinamide mononucleotide transporter
HGHHNEPF_00305 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGHHNEPF_00306 8.8e-99 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HGHHNEPF_00307 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGHHNEPF_00308 6.8e-196 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HGHHNEPF_00309 0.0 dnaK O Heat shock 70 kDa protein
HGHHNEPF_00310 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGHHNEPF_00311 1.2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HGHHNEPF_00312 7.6e-64
HGHHNEPF_00313 2.2e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HGHHNEPF_00314 2.6e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGHHNEPF_00315 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGHHNEPF_00316 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGHHNEPF_00317 4.5e-49 ylxQ J ribosomal protein
HGHHNEPF_00318 2.3e-44 ylxR K Protein of unknown function (DUF448)
HGHHNEPF_00319 1.2e-214 nusA K Participates in both transcription termination and antitermination
HGHHNEPF_00320 1.9e-83 rimP J Required for maturation of 30S ribosomal subunits
HGHHNEPF_00321 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGHHNEPF_00322 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HGHHNEPF_00323 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HGHHNEPF_00324 9.9e-138 cdsA 2.7.7.41 I Belongs to the CDS family
HGHHNEPF_00325 4.8e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGHHNEPF_00326 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HGHHNEPF_00327 1.3e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HGHHNEPF_00328 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGHHNEPF_00329 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HGHHNEPF_00330 2.2e-182 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHHNEPF_00331 3.9e-47 yazA L GIY-YIG catalytic domain protein
HGHHNEPF_00332 7.8e-140 yabB 2.1.1.223 L Methyltransferase small domain
HGHHNEPF_00333 7.8e-117 plsC 2.3.1.51 I Acyltransferase
HGHHNEPF_00334 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HGHHNEPF_00335 6.6e-35 ynzC S UPF0291 protein
HGHHNEPF_00336 3.6e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGHHNEPF_00337 2e-211 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HGHHNEPF_00338 4.1e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGHHNEPF_00341 4.9e-16
HGHHNEPF_00342 4.9e-16
HGHHNEPF_00344 3e-168 M MucBP domain
HGHHNEPF_00345 2.5e-88
HGHHNEPF_00346 7.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGHHNEPF_00347 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HGHHNEPF_00348 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGHHNEPF_00349 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HGHHNEPF_00350 2.3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGHHNEPF_00351 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HGHHNEPF_00352 4.9e-08
HGHHNEPF_00353 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HGHHNEPF_00354 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HGHHNEPF_00355 3.1e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGHHNEPF_00356 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HGHHNEPF_00357 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGHHNEPF_00358 3.5e-163 S Tetratricopeptide repeat
HGHHNEPF_00359 1.5e-51 L hmm pf00665
HGHHNEPF_00360 2e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HGHHNEPF_00361 5.7e-120 radC L DNA repair protein
HGHHNEPF_00362 1.7e-179 mreB D cell shape determining protein MreB
HGHHNEPF_00363 7.7e-152 mreC M Involved in formation and maintenance of cell shape
HGHHNEPF_00364 3.3e-92 mreD M rod shape-determining protein MreD
HGHHNEPF_00365 3.2e-102 glnP P ABC transporter permease
HGHHNEPF_00366 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHHNEPF_00367 2.6e-160 aatB ET ABC transporter substrate-binding protein
HGHHNEPF_00368 6.6e-229 ymfF S Peptidase M16 inactive domain protein
HGHHNEPF_00369 2.5e-247 ymfH S Peptidase M16
HGHHNEPF_00370 3.1e-139 ymfM S Helix-turn-helix domain
HGHHNEPF_00371 3.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGHHNEPF_00372 1.1e-228 cinA 3.5.1.42 S Belongs to the CinA family
HGHHNEPF_00373 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGHHNEPF_00374 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
HGHHNEPF_00375 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGHHNEPF_00376 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGHHNEPF_00377 3.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HGHHNEPF_00378 4.5e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HGHHNEPF_00379 6.7e-201 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HGHHNEPF_00380 6.2e-31 yajC U Preprotein translocase
HGHHNEPF_00381 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HGHHNEPF_00382 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HGHHNEPF_00383 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGHHNEPF_00384 4.1e-43 yrzL S Belongs to the UPF0297 family
HGHHNEPF_00385 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGHHNEPF_00386 6.1e-48 yrzB S Belongs to the UPF0473 family
HGHHNEPF_00387 1e-85 cvpA S Colicin V production protein
HGHHNEPF_00388 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HGHHNEPF_00389 6.1e-54 trxA O Belongs to the thioredoxin family
HGHHNEPF_00390 5.1e-96 yslB S Protein of unknown function (DUF2507)
HGHHNEPF_00391 3.2e-144 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HGHHNEPF_00392 2.4e-104 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGHHNEPF_00393 7.6e-94 S Phosphoesterase
HGHHNEPF_00394 3.6e-76 ykuL S (CBS) domain
HGHHNEPF_00395 1e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HGHHNEPF_00396 4e-148 ykuT M mechanosensitive ion channel
HGHHNEPF_00397 1.2e-36 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HGHHNEPF_00398 5.6e-08
HGHHNEPF_00399 9.4e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HGHHNEPF_00400 4.5e-183 ccpA K catabolite control protein A
HGHHNEPF_00401 2.5e-134
HGHHNEPF_00402 1e-131 yebC K Transcriptional regulatory protein
HGHHNEPF_00403 4.3e-183 comGA NU Type II IV secretion system protein
HGHHNEPF_00404 1.7e-182 comGB NU type II secretion system
HGHHNEPF_00405 7.9e-46 comGC U competence protein ComGC
HGHHNEPF_00406 1.4e-77 NU general secretion pathway protein
HGHHNEPF_00407 7.1e-41
HGHHNEPF_00408 2.4e-69
HGHHNEPF_00409 1.3e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
HGHHNEPF_00410 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGHHNEPF_00411 5.7e-117 S Calcineurin-like phosphoesterase
HGHHNEPF_00412 5.7e-100 yutD S Protein of unknown function (DUF1027)
HGHHNEPF_00413 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HGHHNEPF_00414 5.4e-113 S Protein of unknown function (DUF1461)
HGHHNEPF_00415 1.6e-109 dedA S SNARE-like domain protein
HGHHNEPF_00416 1.6e-141 acmD M repeat protein
HGHHNEPF_00417 1.8e-195 S enterobacterial common antigen metabolic process
HGHHNEPF_00418 1.6e-193 M transferase activity, transferring glycosyl groups
HGHHNEPF_00419 9.3e-200 waaB GT4 M Glycosyl transferases group 1
HGHHNEPF_00420 8.3e-260 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HGHHNEPF_00421 1.4e-105 M biosynthesis protein
HGHHNEPF_00422 1.6e-216 cps3F
HGHHNEPF_00423 3.9e-220 glf 5.4.99.9 M UDP-galactopyranose mutase
HGHHNEPF_00424 5.1e-116 rfbP 2.7.8.6 M Bacterial sugar transferase
HGHHNEPF_00425 8e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HGHHNEPF_00426 6.7e-147 cps1D M Domain of unknown function (DUF4422)
HGHHNEPF_00427 7.4e-141 recX 2.4.1.337 GT4 S Regulatory protein RecX
HGHHNEPF_00428 1.9e-30
HGHHNEPF_00429 1.9e-33 S Protein of unknown function (DUF2922)
HGHHNEPF_00430 1.5e-153 yihY S Belongs to the UPF0761 family
HGHHNEPF_00431 2e-280 yjeM E Amino Acid
HGHHNEPF_00432 2.5e-256 E Arginine ornithine antiporter
HGHHNEPF_00433 1.3e-220 arcT 2.6.1.1 E Aminotransferase
HGHHNEPF_00434 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
HGHHNEPF_00435 3.9e-78 fld C Flavodoxin
HGHHNEPF_00436 2.3e-67 gtcA S Teichoic acid glycosylation protein
HGHHNEPF_00437 2.1e-55
HGHHNEPF_00438 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGHHNEPF_00440 2.5e-231 yfmL L DEAD DEAH box helicase
HGHHNEPF_00441 1.3e-190 mocA S Oxidoreductase
HGHHNEPF_00442 9.1e-62 S Domain of unknown function (DUF4828)
HGHHNEPF_00443 2e-103 yvdD 3.2.2.10 S Belongs to the LOG family
HGHHNEPF_00444 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HGHHNEPF_00445 2.1e-293 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HGHHNEPF_00446 1.7e-190 S Protein of unknown function (DUF3114)
HGHHNEPF_00447 5e-73 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HGHHNEPF_00448 5.4e-119 ybhL S Belongs to the BI1 family
HGHHNEPF_00449 5.5e-21
HGHHNEPF_00450 5.2e-72 K LytTr DNA-binding domain
HGHHNEPF_00451 1.2e-68 S Protein of unknown function (DUF3021)
HGHHNEPF_00452 8.4e-136 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HGHHNEPF_00453 1.5e-22 XK27_00915 C Luciferase-like monooxygenase
HGHHNEPF_00454 5.4e-121 pnb C nitroreductase
HGHHNEPF_00455 2.9e-88
HGHHNEPF_00456 2.3e-243 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HGHHNEPF_00457 1.1e-38 amtB P ammonium transporter
HGHHNEPF_00458 7.6e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HGHHNEPF_00460 1.1e-47
HGHHNEPF_00461 1.1e-153 cylA V ABC transporter
HGHHNEPF_00462 4.5e-144 cylB V ABC-2 type transporter
HGHHNEPF_00463 7.6e-74 K LytTr DNA-binding domain
HGHHNEPF_00464 1.8e-60 S Protein of unknown function (DUF3021)
HGHHNEPF_00466 2.2e-176 L Plasmid pRiA4b ORF-3-like protein
HGHHNEPF_00467 2e-71 1.6.5.2 S NADPH-dependent FMN reductase
HGHHNEPF_00468 1.3e-85 K Bacterial regulatory proteins, tetR family
HGHHNEPF_00469 5e-87 entB 3.5.1.19 Q Isochorismatase family
HGHHNEPF_00470 2.1e-66 K Psort location Cytoplasmic, score
HGHHNEPF_00471 8.8e-35 K DNA binding
HGHHNEPF_00472 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
HGHHNEPF_00473 2.4e-222 mod 2.1.1.72, 3.1.21.5 L DNA methylase
HGHHNEPF_00474 5.4e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HGHHNEPF_00475 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGHHNEPF_00476 1.7e-207 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGHHNEPF_00477 3.1e-245 M Glycosyl transferase family group 2
HGHHNEPF_00479 2.1e-224 aadAT EK Aminotransferase, class I
HGHHNEPF_00480 1.5e-31 S Predicted membrane protein (DUF2207)
HGHHNEPF_00481 6.7e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HGHHNEPF_00482 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGHHNEPF_00483 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HGHHNEPF_00484 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HGHHNEPF_00485 1e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGHHNEPF_00486 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HGHHNEPF_00487 3.8e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGHHNEPF_00488 2.3e-207 yacL S domain protein
HGHHNEPF_00489 2.5e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGHHNEPF_00490 3.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HGHHNEPF_00491 7.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HGHHNEPF_00492 7.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HGHHNEPF_00493 9.5e-266 pepC 3.4.22.40 E Peptidase C1-like family
HGHHNEPF_00494 4.3e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HGHHNEPF_00495 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHHNEPF_00496 1.1e-119 tcyB E ABC transporter
HGHHNEPF_00497 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HGHHNEPF_00498 1.1e-169 I alpha/beta hydrolase fold
HGHHNEPF_00499 6e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGHHNEPF_00500 0.0 S Bacterial membrane protein, YfhO
HGHHNEPF_00501 2.5e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HGHHNEPF_00502 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HGHHNEPF_00504 2.8e-84 ydcK S Belongs to the SprT family
HGHHNEPF_00505 0.0 yhgF K Tex-like protein N-terminal domain protein
HGHHNEPF_00506 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HGHHNEPF_00507 5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGHHNEPF_00508 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
HGHHNEPF_00509 1.1e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HGHHNEPF_00510 1.2e-302 aspT P Predicted Permease Membrane Region
HGHHNEPF_00511 2.2e-249 EGP Major facilitator Superfamily
HGHHNEPF_00512 1e-111
HGHHNEPF_00515 1.8e-50 yjjH S Calcineurin-like phosphoesterase
HGHHNEPF_00516 4.2e-89 yjjH S Calcineurin-like phosphoesterase
HGHHNEPF_00517 1.3e-263 dtpT U amino acid peptide transporter
HGHHNEPF_00518 2.4e-18
HGHHNEPF_00520 1.7e-168 yqiG C Oxidoreductase
HGHHNEPF_00521 4.1e-62 S macrophage migration inhibitory factor
HGHHNEPF_00522 1.8e-65 K HxlR-like helix-turn-helix
HGHHNEPF_00523 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGHHNEPF_00524 1.4e-58
HGHHNEPF_00525 1.3e-224 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGHHNEPF_00527 1.7e-111 lssY 3.6.1.27 I Acid phosphatase homologues
HGHHNEPF_00528 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HGHHNEPF_00529 1.7e-227 clcA_2 P Chloride transporter, ClC family
HGHHNEPF_00530 8.5e-119 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HGHHNEPF_00531 1.8e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HGHHNEPF_00532 6.2e-64 L Belongs to the 'phage' integrase family
HGHHNEPF_00536 1.1e-10
HGHHNEPF_00537 3.5e-20 E Zn peptidase
HGHHNEPF_00538 8.9e-50 ps115 K Helix-turn-helix XRE-family like proteins
HGHHNEPF_00539 2.6e-13
HGHHNEPF_00547 4e-162 recT L RecT family
HGHHNEPF_00548 1.9e-149 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HGHHNEPF_00549 7.3e-47 ybl78 L Conserved phage C-terminus (Phg_2220_C)
HGHHNEPF_00550 5.1e-27
HGHHNEPF_00554 4e-16
HGHHNEPF_00555 1e-54 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HGHHNEPF_00557 2.3e-81 Q DNA (cytosine-5-)-methyltransferase activity
HGHHNEPF_00558 3.9e-22
HGHHNEPF_00561 2.6e-16
HGHHNEPF_00564 1.4e-83 arpU S Phage transcriptional regulator, ArpU family
HGHHNEPF_00565 7.2e-121 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
HGHHNEPF_00566 1.4e-66
HGHHNEPF_00568 1.5e-109 K Belongs to the N(4) N(6)-methyltransferase family
HGHHNEPF_00570 2.2e-259 S Phage terminase, large subunit
HGHHNEPF_00571 3.5e-310 S Phage portal protein, SPP1 Gp6-like
HGHHNEPF_00572 4.2e-167 S Phage Mu protein F like protein
HGHHNEPF_00574 2.1e-96 S Domain of unknown function (DUF4355)
HGHHNEPF_00575 5.2e-198 gpG
HGHHNEPF_00576 1.3e-60 S Phage gp6-like head-tail connector protein
HGHHNEPF_00577 7.9e-46
HGHHNEPF_00578 1.8e-77
HGHHNEPF_00579 1.2e-70
HGHHNEPF_00580 9.1e-121
HGHHNEPF_00581 1.5e-92 S Phage tail assembly chaperone protein, TAC
HGHHNEPF_00582 1.2e-240 D NLP P60 protein
HGHHNEPF_00583 1.2e-168 S Phage tail protein
HGHHNEPF_00584 0.0 M CHAP domain
HGHHNEPF_00587 1.1e-49 S Calcineurin-like phosphoesterase
HGHHNEPF_00590 4.4e-55 S Bacteriophage holin family
HGHHNEPF_00591 2.3e-73 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HGHHNEPF_00592 1.1e-151 M Glycosyl hydrolases family 25
HGHHNEPF_00593 4.1e-13
HGHHNEPF_00594 1.1e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HGHHNEPF_00595 4.1e-253 comFA L Helicase C-terminal domain protein
HGHHNEPF_00596 7.5e-126 comFC S Competence protein
HGHHNEPF_00597 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGHHNEPF_00598 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGHHNEPF_00599 7.8e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGHHNEPF_00600 5.9e-31 KT PspC domain protein
HGHHNEPF_00601 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HGHHNEPF_00602 6.6e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HGHHNEPF_00603 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGHHNEPF_00604 5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HGHHNEPF_00605 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HGHHNEPF_00606 2.8e-134 yrjD S LUD domain
HGHHNEPF_00607 9.8e-288 lutB C 4Fe-4S dicluster domain
HGHHNEPF_00608 5.6e-166 lutA C Cysteine-rich domain
HGHHNEPF_00609 3.9e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HGHHNEPF_00610 6.9e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HGHHNEPF_00611 5.9e-163 aatB ET PFAM extracellular solute-binding protein, family 3
HGHHNEPF_00612 3.9e-87 ykhA 3.1.2.20 I Thioesterase superfamily
HGHHNEPF_00613 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HGHHNEPF_00614 5.1e-116 yfbR S HD containing hydrolase-like enzyme
HGHHNEPF_00615 6.9e-14
HGHHNEPF_00616 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HGHHNEPF_00617 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HGHHNEPF_00618 1.1e-245 steT E amino acid
HGHHNEPF_00619 1.7e-162 rapZ S Displays ATPase and GTPase activities
HGHHNEPF_00620 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HGHHNEPF_00621 3.1e-170 whiA K May be required for sporulation
HGHHNEPF_00623 8.8e-15
HGHHNEPF_00624 3.7e-241 glpT G Major Facilitator Superfamily
HGHHNEPF_00625 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGHHNEPF_00627 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGHHNEPF_00628 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HGHHNEPF_00629 6.3e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGHHNEPF_00630 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGHHNEPF_00631 1.2e-247 yifK E Amino acid permease
HGHHNEPF_00632 6.9e-292 clcA P chloride
HGHHNEPF_00633 1.8e-34 secG U Preprotein translocase
HGHHNEPF_00634 2.8e-145 est 3.1.1.1 S Serine aminopeptidase, S33
HGHHNEPF_00635 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HGHHNEPF_00636 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HGHHNEPF_00637 2.6e-103 yxjI
HGHHNEPF_00638 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGHHNEPF_00639 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HGHHNEPF_00640 6.5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HGHHNEPF_00641 3e-87 K Acetyltransferase (GNAT) domain
HGHHNEPF_00642 3.8e-75 S PAS domain
HGHHNEPF_00643 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
HGHHNEPF_00644 4.7e-168 murB 1.3.1.98 M Cell wall formation
HGHHNEPF_00645 3.8e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGHHNEPF_00646 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HGHHNEPF_00647 2.4e-248 fucP G Major Facilitator Superfamily
HGHHNEPF_00648 1.9e-127 L Helix-turn-helix domain
HGHHNEPF_00649 3.2e-121 L hmm pf00665
HGHHNEPF_00650 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGHHNEPF_00651 1.1e-124 ybbR S YbbR-like protein
HGHHNEPF_00652 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGHHNEPF_00653 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HGHHNEPF_00654 8.7e-53
HGHHNEPF_00655 0.0 oatA I Acyltransferase
HGHHNEPF_00656 2.3e-81 K Transcriptional regulator
HGHHNEPF_00657 2.8e-143 XK27_02985 S Cof-like hydrolase
HGHHNEPF_00658 5.3e-78 lytE M Lysin motif
HGHHNEPF_00660 4.4e-132 K response regulator
HGHHNEPF_00661 2.7e-269 yclK 2.7.13.3 T Histidine kinase
HGHHNEPF_00662 2.6e-155 glcU U sugar transport
HGHHNEPF_00663 4.4e-101 lacA 2.3.1.79 S Transferase hexapeptide repeat
HGHHNEPF_00664 3.4e-263 pgi 5.3.1.9 G Belongs to the GPI family
HGHHNEPF_00665 8.5e-28
HGHHNEPF_00666 3e-215 xylR GK ROK family
HGHHNEPF_00668 6.2e-260 xylT EGP Major facilitator Superfamily
HGHHNEPF_00669 1.9e-172 rhaS2 K Transcriptional regulator, AraC family
HGHHNEPF_00670 6.9e-289 xynT G MFS/sugar transport protein
HGHHNEPF_00671 0.0 3.2.1.55 GH51 G Right handed beta helix region
HGHHNEPF_00672 6e-20 pgdA 3.5.1.104 G polysaccharide deacetylase
HGHHNEPF_00673 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
HGHHNEPF_00674 1.3e-270 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HGHHNEPF_00675 3.3e-299 xylB 2.7.1.17 G Belongs to the FGGY kinase family
HGHHNEPF_00676 1.2e-154 KT YcbB domain
HGHHNEPF_00677 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGHHNEPF_00678 2.1e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HGHHNEPF_00679 3.9e-162 EG EamA-like transporter family
HGHHNEPF_00680 1.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HGHHNEPF_00681 5.6e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HGHHNEPF_00682 8.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HGHHNEPF_00683 0.0 copA 3.6.3.54 P P-type ATPase
HGHHNEPF_00684 1.7e-87
HGHHNEPF_00686 3.6e-57
HGHHNEPF_00687 8.5e-150 yjcE P Sodium proton antiporter
HGHHNEPF_00688 2.2e-38 yjcE P Sodium proton antiporter
HGHHNEPF_00690 2.2e-90
HGHHNEPF_00691 0.0 M domain protein
HGHHNEPF_00692 1.2e-18
HGHHNEPF_00693 2e-186 ampC V Beta-lactamase
HGHHNEPF_00694 9.1e-239 arcA 3.5.3.6 E Arginine
HGHHNEPF_00695 2.7e-79 argR K Regulates arginine biosynthesis genes
HGHHNEPF_00696 1.5e-261 E Arginine ornithine antiporter
HGHHNEPF_00697 6.7e-222 arcD U Amino acid permease
HGHHNEPF_00698 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HGHHNEPF_00699 1.7e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HGHHNEPF_00700 6e-108 tdk 2.7.1.21 F thymidine kinase
HGHHNEPF_00701 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGHHNEPF_00702 6.8e-164 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HGHHNEPF_00703 1.4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HGHHNEPF_00704 3.5e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HGHHNEPF_00705 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGHHNEPF_00706 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGHHNEPF_00707 1.3e-191 yibE S overlaps another CDS with the same product name
HGHHNEPF_00708 7e-128 yibF S overlaps another CDS with the same product name
HGHHNEPF_00709 6.5e-232 pyrP F Permease
HGHHNEPF_00710 4.7e-123 atpB C it plays a direct role in the translocation of protons across the membrane
HGHHNEPF_00711 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGHHNEPF_00712 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGHHNEPF_00713 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGHHNEPF_00714 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGHHNEPF_00715 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGHHNEPF_00716 5.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGHHNEPF_00717 5.9e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HGHHNEPF_00718 2.2e-33 ywzB S Protein of unknown function (DUF1146)
HGHHNEPF_00719 2.5e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGHHNEPF_00720 5.5e-178 mbl D Cell shape determining protein MreB Mrl
HGHHNEPF_00721 1e-31 S Protein of unknown function (DUF2969)
HGHHNEPF_00722 3.2e-220 rodA D Belongs to the SEDS family
HGHHNEPF_00723 1.8e-47 gcvH E glycine cleavage
HGHHNEPF_00724 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HGHHNEPF_00725 9.6e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HGHHNEPF_00726 7.5e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HGHHNEPF_00727 0.0 araB 2.7.1.16 G carbohydrate kinase FGGY
HGHHNEPF_00728 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HGHHNEPF_00729 2.4e-283 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HGHHNEPF_00730 3.2e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
HGHHNEPF_00731 2.3e-156 ytbE 1.1.1.346 S Aldo keto reductase
HGHHNEPF_00732 5.9e-205 araR K Transcriptional regulator
HGHHNEPF_00733 4.3e-83 usp6 T universal stress protein
HGHHNEPF_00734 5.7e-46
HGHHNEPF_00735 4.6e-241 rarA L recombination factor protein RarA
HGHHNEPF_00736 2.5e-86 yueI S Protein of unknown function (DUF1694)
HGHHNEPF_00737 1.2e-21
HGHHNEPF_00738 8.1e-75 4.4.1.5 E Glyoxalase
HGHHNEPF_00739 1.2e-137 S Membrane
HGHHNEPF_00740 3e-136 S Belongs to the UPF0246 family
HGHHNEPF_00741 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HGHHNEPF_00742 4.1e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HGHHNEPF_00743 1.3e-233 pbuG S permease
HGHHNEPF_00744 4.1e-242 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HGHHNEPF_00745 3.1e-206 E Amino acid permease
HGHHNEPF_00746 0.0 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
HGHHNEPF_00747 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGHHNEPF_00748 5.8e-252 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HGHHNEPF_00749 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HGHHNEPF_00750 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGHHNEPF_00751 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HGHHNEPF_00752 7.2e-272 cydA 1.10.3.14 C ubiquinol oxidase
HGHHNEPF_00753 1.4e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HGHHNEPF_00754 1.7e-307 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HGHHNEPF_00755 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HGHHNEPF_00756 4.5e-230 ndh 1.6.99.3 C NADH dehydrogenase
HGHHNEPF_00757 2.6e-237 lmrB EGP Major facilitator Superfamily
HGHHNEPF_00758 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HGHHNEPF_00759 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGHHNEPF_00760 1.5e-109 sufD O Uncharacterized protein family (UPF0051)
HGHHNEPF_00761 6.7e-81 lytE M LysM domain protein
HGHHNEPF_00762 0.0 oppD EP Psort location Cytoplasmic, score
HGHHNEPF_00763 3.3e-92 lytE M LysM domain protein
HGHHNEPF_00764 9.2e-149 xth 3.1.11.2 L exodeoxyribonuclease III
HGHHNEPF_00765 2.1e-114 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HGHHNEPF_00766 1.7e-142 preA 1.3.1.1 C 4Fe-4S dicluster domain
HGHHNEPF_00767 1.3e-151 yeaE S Aldo keto
HGHHNEPF_00768 7e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HGHHNEPF_00769 4e-281 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HGHHNEPF_00770 4.5e-79 S Psort location Cytoplasmic, score
HGHHNEPF_00771 2.9e-85 S Short repeat of unknown function (DUF308)
HGHHNEPF_00772 1e-23
HGHHNEPF_00773 2.8e-102 V VanZ like family
HGHHNEPF_00774 1.5e-231 cycA E Amino acid permease
HGHHNEPF_00775 1.6e-84 perR P Belongs to the Fur family
HGHHNEPF_00776 6.7e-257 EGP Major facilitator Superfamily
HGHHNEPF_00777 1.3e-93 tag 3.2.2.20 L glycosylase
HGHHNEPF_00778 4.3e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGHHNEPF_00779 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGHHNEPF_00780 4.5e-42
HGHHNEPF_00781 1e-301 ytgP S Polysaccharide biosynthesis protein
HGHHNEPF_00782 1.7e-28
HGHHNEPF_00783 5.2e-29
HGHHNEPF_00785 2e-18 K Cro/C1-type HTH DNA-binding domain
HGHHNEPF_00786 7.5e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGHHNEPF_00787 2.5e-277 pepV 3.5.1.18 E dipeptidase PepV
HGHHNEPF_00788 4.3e-86 uspA T Belongs to the universal stress protein A family
HGHHNEPF_00789 9.2e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGHHNEPF_00790 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
HGHHNEPF_00791 1.5e-112
HGHHNEPF_00792 2.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HGHHNEPF_00793 2e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGHHNEPF_00794 2.1e-32
HGHHNEPF_00795 7.5e-118 S CAAX protease self-immunity
HGHHNEPF_00796 1.9e-43
HGHHNEPF_00798 1.9e-54
HGHHNEPF_00799 2.1e-143 S Domain of unknown function DUF1829
HGHHNEPF_00800 1.5e-73
HGHHNEPF_00801 1.1e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGHHNEPF_00802 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HGHHNEPF_00803 1.2e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HGHHNEPF_00804 2.1e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HGHHNEPF_00805 1.8e-102 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HGHHNEPF_00806 3.1e-212 folP 2.5.1.15 H dihydropteroate synthase
HGHHNEPF_00807 3e-43
HGHHNEPF_00808 3.3e-40
HGHHNEPF_00810 5.4e-78 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGHHNEPF_00811 1.5e-48
HGHHNEPF_00813 5e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HGHHNEPF_00814 1.1e-56 K transcriptional regulator PadR family
HGHHNEPF_00815 4.9e-84 XK27_06920 S Protein of unknown function (DUF1700)
HGHHNEPF_00816 1.8e-136 S Putative adhesin
HGHHNEPF_00817 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HGHHNEPF_00818 1.3e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGHHNEPF_00819 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGHHNEPF_00820 3.4e-35 nrdH O Glutaredoxin
HGHHNEPF_00821 2.7e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HGHHNEPF_00822 4.6e-287 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGHHNEPF_00823 4.6e-46 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HGHHNEPF_00824 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGHHNEPF_00825 9.7e-39 S Protein of unknown function (DUF2508)
HGHHNEPF_00826 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGHHNEPF_00827 7.6e-52 yaaQ S Cyclic-di-AMP receptor
HGHHNEPF_00828 1.8e-184 holB 2.7.7.7 L DNA polymerase III
HGHHNEPF_00829 1.7e-57 yabA L Involved in initiation control of chromosome replication
HGHHNEPF_00830 3.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGHHNEPF_00831 8.1e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
HGHHNEPF_00832 3.4e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGHHNEPF_00833 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HGHHNEPF_00834 1.3e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGHHNEPF_00835 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HGHHNEPF_00836 3.6e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HGHHNEPF_00837 4.7e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HGHHNEPF_00838 8e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGHHNEPF_00839 3.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGHHNEPF_00840 7.6e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGHHNEPF_00841 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGHHNEPF_00842 3.3e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HGHHNEPF_00843 6.9e-228 mtnE 2.6.1.83 E Aminotransferase
HGHHNEPF_00844 6.2e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGHHNEPF_00845 1.2e-309 uup S ABC transporter, ATP-binding protein
HGHHNEPF_00846 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HGHHNEPF_00848 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGHHNEPF_00849 1.8e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HGHHNEPF_00850 1.1e-32 S YbaK proline--tRNA ligase associated domain protein
HGHHNEPF_00851 4.1e-33 S Aminoacyl-tRNA editing domain
HGHHNEPF_00852 2.4e-303 ybeC E amino acid
HGHHNEPF_00853 0.0 ydaO E amino acid
HGHHNEPF_00854 3e-38
HGHHNEPF_00855 6.3e-51 rmaI K Transcriptional regulator
HGHHNEPF_00856 1.4e-152 yaaU EGP Major facilitator Superfamily
HGHHNEPF_00857 4.7e-39 EGP Major facilitator Superfamily
HGHHNEPF_00858 1.5e-51 L hmm pf00665
HGHHNEPF_00861 1.3e-35 S Bacteriophage holin family
HGHHNEPF_00862 4.7e-57 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HGHHNEPF_00863 4.4e-200 3.5.1.104 M hydrolase, family 25
HGHHNEPF_00864 2.5e-34 S Bacteriophage abortive infection AbiH
HGHHNEPF_00865 2.3e-30 S Protein of unknown function (DUF2929)
HGHHNEPF_00866 0.0 dnaE 2.7.7.7 L DNA polymerase
HGHHNEPF_00867 8e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HGHHNEPF_00868 3e-167 cvfB S S1 domain
HGHHNEPF_00869 3.5e-163 xerD D recombinase XerD
HGHHNEPF_00870 1.6e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGHHNEPF_00871 4.8e-140 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HGHHNEPF_00872 1.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HGHHNEPF_00873 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HGHHNEPF_00874 1.6e-70 L Belongs to the 'phage' integrase family
HGHHNEPF_00875 9.3e-26
HGHHNEPF_00878 8.1e-76 E IrrE N-terminal-like domain
HGHHNEPF_00879 1.4e-48 K Cro/C1-type HTH DNA-binding domain
HGHHNEPF_00880 1.3e-20
HGHHNEPF_00881 9.6e-111 S Protein of unknown function (DUF3102)
HGHHNEPF_00883 5.4e-08
HGHHNEPF_00887 3.8e-07
HGHHNEPF_00889 1.7e-54 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HGHHNEPF_00890 4.6e-131 S Putative HNHc nuclease
HGHHNEPF_00891 1e-34 L Psort location Cytoplasmic, score
HGHHNEPF_00894 3.7e-36
HGHHNEPF_00895 2.7e-31
HGHHNEPF_00896 3.4e-74 rusA L Endodeoxyribonuclease RusA
HGHHNEPF_00904 1.6e-162
HGHHNEPF_00905 2.3e-122 dck 2.7.1.74 F deoxynucleoside kinase
HGHHNEPF_00910 2.5e-74 S Transcriptional regulator, RinA family
HGHHNEPF_00912 9.8e-28 S Domain of unknown function (DUF4868)
HGHHNEPF_00913 8.9e-11
HGHHNEPF_00919 7.6e-39 S sequence-specific DNA binding transcription factor activity
HGHHNEPF_00920 1.5e-113 pnuC H nicotinamide mononucleotide transporter
HGHHNEPF_00923 5.8e-23 N mRNA binding
HGHHNEPF_00924 3.3e-57 S HicB_like antitoxin of bacterial toxin-antitoxin system
HGHHNEPF_00925 1.4e-177 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HGHHNEPF_00926 7.3e-138 IQ KR domain
HGHHNEPF_00927 5.2e-117 fhaB M Rib/alpha-like repeat
HGHHNEPF_00928 1.2e-134 fhaB M translation initiation factor activity
HGHHNEPF_00930 9.9e-130 S membrane transporter protein
HGHHNEPF_00931 2.7e-216 yjeM E Amino Acid
HGHHNEPF_00932 2.5e-95 S ABC-type cobalt transport system, permease component
HGHHNEPF_00933 7.8e-239 cbiO1 S ABC transporter, ATP-binding protein
HGHHNEPF_00934 2.3e-111 P Cobalt transport protein
HGHHNEPF_00935 1.6e-52 yvlA
HGHHNEPF_00936 0.0 yjcE P Sodium proton antiporter
HGHHNEPF_00937 2.2e-52 ypaA S Protein of unknown function (DUF1304)
HGHHNEPF_00938 4.8e-190 D Alpha beta
HGHHNEPF_00939 1e-72 K Transcriptional regulator
HGHHNEPF_00940 3.5e-160
HGHHNEPF_00941 4e-16 1.6.5.5 C Zinc-binding dehydrogenase
HGHHNEPF_00942 5.6e-75 1.6.5.5 C Zinc-binding dehydrogenase
HGHHNEPF_00943 6.4e-38 1.6.5.5 C Zinc-binding dehydrogenase
HGHHNEPF_00944 2.1e-255 G PTS system Galactitol-specific IIC component
HGHHNEPF_00945 2.4e-212 EGP Major facilitator Superfamily
HGHHNEPF_00946 8.8e-135 V ABC transporter
HGHHNEPF_00947 3.3e-108
HGHHNEPF_00948 5.2e-14
HGHHNEPF_00949 7.1e-63
HGHHNEPF_00950 8.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HGHHNEPF_00951 5.1e-81 uspA T universal stress protein
HGHHNEPF_00952 0.0 tetP J elongation factor G
HGHHNEPF_00953 1.4e-167 GK ROK family
HGHHNEPF_00954 1.4e-240 brnQ U Component of the transport system for branched-chain amino acids
HGHHNEPF_00955 9.4e-138 aroD S Serine hydrolase (FSH1)
HGHHNEPF_00956 1.5e-242 yagE E amino acid
HGHHNEPF_00957 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HGHHNEPF_00958 1.5e-132 gntR K UbiC transcription regulator-associated domain protein
HGHHNEPF_00959 1e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGHHNEPF_00960 1.4e-283 pipD E Dipeptidase
HGHHNEPF_00961 0.0 yfiC V ABC transporter
HGHHNEPF_00962 1.7e-307 lmrA V ABC transporter, ATP-binding protein
HGHHNEPF_00963 1.1e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHHNEPF_00965 1.4e-261 nox C NADH oxidase
HGHHNEPF_00966 3.3e-86 hmpT S ECF-type riboflavin transporter, S component
HGHHNEPF_00967 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HGHHNEPF_00968 5.2e-47 1.14.12.17 S Cupin 2, conserved barrel domain protein
HGHHNEPF_00969 1.7e-167 yvgN C Aldo keto reductase
HGHHNEPF_00970 1.1e-135 puuD S peptidase C26
HGHHNEPF_00971 5.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HGHHNEPF_00972 2.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HGHHNEPF_00973 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HGHHNEPF_00974 1.1e-256 malT G Major Facilitator
HGHHNEPF_00975 5.7e-206 phbA 2.3.1.9 I Belongs to the thiolase family
HGHHNEPF_00976 7.3e-172 malR K Transcriptional regulator, LacI family
HGHHNEPF_00977 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HGHHNEPF_00978 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HGHHNEPF_00979 2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGHHNEPF_00980 8.8e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
HGHHNEPF_00982 7.8e-165 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HGHHNEPF_00983 0.0 clpL O associated with various cellular activities
HGHHNEPF_00984 2.7e-32
HGHHNEPF_00985 1.8e-212 patA 2.6.1.1 E Aminotransferase
HGHHNEPF_00986 1.2e-175 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGHHNEPF_00987 2.9e-75 osmC O OsmC-like protein
HGHHNEPF_00989 1.6e-246 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HGHHNEPF_00991 1.1e-138 K LytTr DNA-binding domain
HGHHNEPF_00992 1e-227 2.7.13.3 T GHKL domain
HGHHNEPF_00993 1.5e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGHHNEPF_00994 2.6e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HGHHNEPF_00995 1.3e-142 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
HGHHNEPF_00996 1.6e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
HGHHNEPF_00997 2.3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HGHHNEPF_00998 8.2e-224 mdtG EGP Major facilitator Superfamily
HGHHNEPF_00999 2.7e-165 T Calcineurin-like phosphoesterase superfamily domain
HGHHNEPF_01000 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGHHNEPF_01002 1.4e-116 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HGHHNEPF_01003 7.2e-137 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HGHHNEPF_01004 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
HGHHNEPF_01005 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HGHHNEPF_01006 0.0 M LPXTG-motif cell wall anchor domain protein
HGHHNEPF_01007 9.2e-189 nss M transferase activity, transferring glycosyl groups
HGHHNEPF_01008 5.5e-30 cpsJ S glycosyl transferase family 2
HGHHNEPF_01009 4.2e-39 cpsJ S glycosyl transferase family 2
HGHHNEPF_01010 2.5e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HGHHNEPF_01011 3.8e-287 M transferase activity, transferring glycosyl groups
HGHHNEPF_01012 4.1e-286 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HGHHNEPF_01013 1.8e-164 asp3 S Accessory Sec secretory system ASP3
HGHHNEPF_01014 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGHHNEPF_01015 1.7e-290 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HGHHNEPF_01016 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HGHHNEPF_01018 3.2e-305 M family 8
HGHHNEPF_01019 3.9e-287 GT2,GT4 M family 8
HGHHNEPF_01022 2.7e-112 ywnB S NAD(P)H-binding
HGHHNEPF_01023 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
HGHHNEPF_01024 2.5e-256 nhaC C Na H antiporter NhaC
HGHHNEPF_01025 5.4e-184 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGHHNEPF_01027 1e-101 ydeN S Serine hydrolase
HGHHNEPF_01028 1.3e-61 psiE S Phosphate-starvation-inducible E
HGHHNEPF_01029 1.6e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGHHNEPF_01031 1.1e-180 S Aldo keto reductase
HGHHNEPF_01032 3.4e-83 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HGHHNEPF_01033 0.0 L Helicase C-terminal domain protein
HGHHNEPF_01035 4.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HGHHNEPF_01036 2.8e-54 S Sugar efflux transporter for intercellular exchange
HGHHNEPF_01037 2.1e-126
HGHHNEPF_01038 2.4e-109 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HGHHNEPF_01039 0.0 cadA P P-type ATPase
HGHHNEPF_01040 4.7e-208 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGHHNEPF_01041 1.4e-72 K Transcriptional regulator
HGHHNEPF_01042 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
HGHHNEPF_01043 8.2e-109 proWZ P ABC transporter permease
HGHHNEPF_01044 9.4e-141 proV E ABC transporter, ATP-binding protein
HGHHNEPF_01045 2.3e-100 proW P ABC transporter, permease protein
HGHHNEPF_01046 2.8e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HGHHNEPF_01047 1.4e-117 clcA P chloride
HGHHNEPF_01048 2.2e-28 clcA P chloride
HGHHNEPF_01049 8.3e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HGHHNEPF_01050 3.1e-103 metI P ABC transporter permease
HGHHNEPF_01051 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGHHNEPF_01052 6.7e-156 metQ1 P Belongs to the nlpA lipoprotein family
HGHHNEPF_01053 2e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HGHHNEPF_01054 4.9e-221 norA EGP Major facilitator Superfamily
HGHHNEPF_01055 4.1e-41 1.3.5.4 S FMN binding
HGHHNEPF_01056 3.5e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGHHNEPF_01057 1.2e-266 yfnA E amino acid
HGHHNEPF_01058 1.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGHHNEPF_01060 4.1e-54 L Transposase, IS116 IS110 IS902 family
HGHHNEPF_01061 4e-41 L Belongs to the 'phage' integrase family
HGHHNEPF_01062 5.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HGHHNEPF_01063 1.4e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGHHNEPF_01064 3.8e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
HGHHNEPF_01065 7e-220 patA 2.6.1.1 E Aminotransferase
HGHHNEPF_01066 6.5e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HGHHNEPF_01067 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HGHHNEPF_01068 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HGHHNEPF_01069 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HGHHNEPF_01070 1.8e-147 recO L Involved in DNA repair and RecF pathway recombination
HGHHNEPF_01071 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGHHNEPF_01072 1.9e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HGHHNEPF_01073 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGHHNEPF_01074 1.1e-181 phoH T phosphate starvation-inducible protein PhoH
HGHHNEPF_01075 1.1e-167 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HGHHNEPF_01076 1.6e-73 bioY S BioY family
HGHHNEPF_01077 1.7e-262 argH 4.3.2.1 E argininosuccinate lyase
HGHHNEPF_01078 1.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HGHHNEPF_01079 2.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGHHNEPF_01080 4.3e-69 yqeY S YqeY-like protein
HGHHNEPF_01081 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HGHHNEPF_01082 8e-261 glnPH2 P ABC transporter permease
HGHHNEPF_01083 1.7e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHHNEPF_01084 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HGHHNEPF_01085 2.7e-165 yniA G Phosphotransferase enzyme family
HGHHNEPF_01086 4.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGHHNEPF_01087 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGHHNEPF_01088 1e-51
HGHHNEPF_01089 1.4e-125 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HGHHNEPF_01090 1.2e-180 prmA J Ribosomal protein L11 methyltransferase
HGHHNEPF_01091 2.2e-57
HGHHNEPF_01093 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGHHNEPF_01094 9.5e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HGHHNEPF_01095 1.8e-150 pipD E Dipeptidase
HGHHNEPF_01096 4.6e-82 pipD E Dipeptidase
HGHHNEPF_01097 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HGHHNEPF_01098 2.9e-99 yceD S Uncharacterized ACR, COG1399
HGHHNEPF_01099 6.1e-213 ylbM S Belongs to the UPF0348 family
HGHHNEPF_01100 4.9e-139 yqeM Q Methyltransferase
HGHHNEPF_01101 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HGHHNEPF_01102 8.6e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HGHHNEPF_01103 6.2e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGHHNEPF_01104 1.9e-47 yhbY J RNA-binding protein
HGHHNEPF_01105 1.2e-216 yqeH S Ribosome biogenesis GTPase YqeH
HGHHNEPF_01106 4.1e-95 yqeG S HAD phosphatase, family IIIA
HGHHNEPF_01107 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGHHNEPF_01108 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HGHHNEPF_01109 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGHHNEPF_01110 3.3e-172 dnaI L Primosomal protein DnaI
HGHHNEPF_01111 2e-226 dnaB L replication initiation and membrane attachment
HGHHNEPF_01112 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HGHHNEPF_01113 1.4e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGHHNEPF_01114 1.3e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HGHHNEPF_01115 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGHHNEPF_01116 1.4e-119 yoaK S Protein of unknown function (DUF1275)
HGHHNEPF_01117 9.3e-119 ybhL S Belongs to the BI1 family
HGHHNEPF_01118 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HGHHNEPF_01119 7.9e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGHHNEPF_01120 6.6e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HGHHNEPF_01121 2e-55 ytzB S Small secreted protein
HGHHNEPF_01122 2.6e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
HGHHNEPF_01123 2.2e-179 iolS C Aldo keto reductase
HGHHNEPF_01124 1.8e-249 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HGHHNEPF_01125 6.9e-83 A chlorophyll binding
HGHHNEPF_01126 2.9e-45 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HGHHNEPF_01127 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HGHHNEPF_01128 1.3e-216 ecsB U ABC transporter
HGHHNEPF_01129 1e-136 ecsA V ABC transporter, ATP-binding protein
HGHHNEPF_01130 8.3e-78 hit FG histidine triad
HGHHNEPF_01132 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HGHHNEPF_01133 0.0 L AAA domain
HGHHNEPF_01134 2.8e-213 yhaO L Ser Thr phosphatase family protein
HGHHNEPF_01135 9.4e-38 yheA S Belongs to the UPF0342 family
HGHHNEPF_01136 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HGHHNEPF_01139 2.7e-78 L Belongs to the 'phage' integrase family
HGHHNEPF_01140 1.3e-10 E Zn peptidase
HGHHNEPF_01141 2.8e-17 XK27_10050 K Peptidase S24-like
HGHHNEPF_01146 4.4e-29 L Psort location Cytoplasmic, score
HGHHNEPF_01174 6.1e-54 srtA 3.4.22.70 M sortase family
HGHHNEPF_01175 8.1e-16
HGHHNEPF_01180 3.7e-25 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HGHHNEPF_01181 7.6e-24 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HGHHNEPF_01182 1e-58 ruvB 3.6.4.12 L four-way junction helicase activity
HGHHNEPF_01184 1.1e-62
HGHHNEPF_01186 6.8e-36 lytE M Lysin motif
HGHHNEPF_01188 1.4e-19 D nuclear chromosome segregation
HGHHNEPF_01189 5.2e-22
HGHHNEPF_01190 7.6e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGHHNEPF_01191 3.1e-163
HGHHNEPF_01192 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGHHNEPF_01193 2.6e-241 purD 6.3.4.13 F Belongs to the GARS family
HGHHNEPF_01194 1.6e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HGHHNEPF_01195 1.2e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGHHNEPF_01196 1.1e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HGHHNEPF_01197 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGHHNEPF_01198 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGHHNEPF_01199 4.4e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGHHNEPF_01200 2.6e-36 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGHHNEPF_01201 5.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HGHHNEPF_01202 3.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGHHNEPF_01203 3.7e-218 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGHHNEPF_01204 7.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGHHNEPF_01205 3.6e-126 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HGHHNEPF_01206 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HGHHNEPF_01207 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HGHHNEPF_01208 1.1e-176 K AI-2E family transporter
HGHHNEPF_01209 1.4e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HGHHNEPF_01210 3.7e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HGHHNEPF_01211 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGHHNEPF_01212 2.7e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HGHHNEPF_01213 1.9e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HGHHNEPF_01214 6.9e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HGHHNEPF_01215 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HGHHNEPF_01216 7.4e-134 K LysR substrate binding domain
HGHHNEPF_01217 5.6e-53 azlD S branched-chain amino acid
HGHHNEPF_01218 3.2e-140 azlC E AzlC protein
HGHHNEPF_01219 1.4e-201 hpk31 2.7.13.3 T Histidine kinase
HGHHNEPF_01220 3.8e-125 K response regulator
HGHHNEPF_01221 7.7e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGHHNEPF_01222 2.8e-171 deoR K sugar-binding domain protein
HGHHNEPF_01223 3.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HGHHNEPF_01224 4.5e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HGHHNEPF_01225 3.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGHHNEPF_01226 2.8e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HGHHNEPF_01227 5.9e-135 XK27_01040 S Protein of unknown function (DUF1129)
HGHHNEPF_01228 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HGHHNEPF_01229 9.1e-32 yyzM S Bacterial protein of unknown function (DUF951)
HGHHNEPF_01230 6.5e-154 spo0J K Belongs to the ParB family
HGHHNEPF_01231 3.9e-139 soj D Sporulation initiation inhibitor
HGHHNEPF_01232 9.6e-151 noc K Belongs to the ParB family
HGHHNEPF_01233 2.3e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HGHHNEPF_01234 8.5e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HGHHNEPF_01235 2.5e-169 rihC 3.2.2.1 F Nucleoside
HGHHNEPF_01236 1.3e-218 nupG F Nucleoside transporter
HGHHNEPF_01237 2.7e-220 cycA E Amino acid permease
HGHHNEPF_01239 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHHNEPF_01240 3e-265 glnP P ABC transporter
HGHHNEPF_01241 8.5e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGHHNEPF_01242 0.0 infB UW LPXTG-motif cell wall anchor domain protein
HGHHNEPF_01243 0.0 fhaB M Rib/alpha-like repeat
HGHHNEPF_01244 1.7e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HGHHNEPF_01245 3.9e-197 XK27_09615 S reductase
HGHHNEPF_01246 2.7e-106 nqr 1.5.1.36 S reductase
HGHHNEPF_01247 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGHHNEPF_01248 1.3e-182 K Transcriptional regulator, LacI family
HGHHNEPF_01249 5.2e-259 G Major Facilitator
HGHHNEPF_01250 1.5e-266 G Major Facilitator
HGHHNEPF_01251 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HGHHNEPF_01252 1.1e-285 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HGHHNEPF_01253 9.4e-262 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HGHHNEPF_01254 7.9e-264 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HGHHNEPF_01255 5.4e-71
HGHHNEPF_01256 6e-109 K Transcriptional regulator, TetR family
HGHHNEPF_01257 2.7e-247 steT_1 E amino acid
HGHHNEPF_01258 9.5e-135 puuD S peptidase C26
HGHHNEPF_01260 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGHHNEPF_01261 1.4e-88
HGHHNEPF_01262 1.5e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGHHNEPF_01263 3.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGHHNEPF_01264 3.2e-121 L hmm pf00665
HGHHNEPF_01265 2.6e-112 L Helix-turn-helix domain
HGHHNEPF_01266 7.2e-09
HGHHNEPF_01267 2.5e-155 P Belongs to the nlpA lipoprotein family
HGHHNEPF_01268 3.9e-12
HGHHNEPF_01269 1.4e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HGHHNEPF_01270 1.3e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGHHNEPF_01271 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
HGHHNEPF_01272 1.6e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGHHNEPF_01273 3.8e-21 S Protein of unknown function (DUF3042)
HGHHNEPF_01274 2.6e-67 yqhL P Rhodanese-like protein
HGHHNEPF_01275 9.6e-183 glk 2.7.1.2 G Glucokinase
HGHHNEPF_01276 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HGHHNEPF_01277 1.6e-112 gluP 3.4.21.105 S Peptidase, S54 family
HGHHNEPF_01278 1.3e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGHHNEPF_01279 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HGHHNEPF_01280 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HGHHNEPF_01281 0.0 S membrane
HGHHNEPF_01282 1.3e-69 yneR S Belongs to the HesB IscA family
HGHHNEPF_01283 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGHHNEPF_01284 7.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
HGHHNEPF_01285 1.2e-114 rlpA M PFAM NLP P60 protein
HGHHNEPF_01286 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGHHNEPF_01287 1.5e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGHHNEPF_01288 6.7e-59 yodB K Transcriptional regulator, HxlR family
HGHHNEPF_01289 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGHHNEPF_01290 4.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGHHNEPF_01291 3.2e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HGHHNEPF_01292 2.6e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGHHNEPF_01293 1.8e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HGHHNEPF_01294 1.5e-231 V MatE
HGHHNEPF_01295 1.9e-267 yjeM E Amino Acid
HGHHNEPF_01296 3.1e-278 arlS 2.7.13.3 T Histidine kinase
HGHHNEPF_01297 1.5e-121 K response regulator
HGHHNEPF_01298 3.7e-52 P Belongs to the ABC transporter superfamily
HGHHNEPF_01299 1.3e-55 EP N-terminal TM domain of oligopeptide transport permease C
HGHHNEPF_01300 1e-48 nikB P Binding-protein-dependent transport system inner membrane component
HGHHNEPF_01301 3.7e-152 nikA E Bacterial extracellular solute-binding proteins, family 5 Middle
HGHHNEPF_01302 1.3e-57 ubiE_1 Q Methyltransferase
HGHHNEPF_01303 9.2e-253 ytjP 3.5.1.18 E Dipeptidase
HGHHNEPF_01304 3.8e-271 arcD S C4-dicarboxylate anaerobic carrier
HGHHNEPF_01305 6.7e-173 yfeX P Peroxidase
HGHHNEPF_01306 2.4e-126 lsa S ABC transporter
HGHHNEPF_01307 5.5e-111 I alpha/beta hydrolase fold
HGHHNEPF_01308 1.5e-166 L transposase, IS605 OrfB family
HGHHNEPF_01309 1.2e-172 MA20_14895 S Conserved hypothetical protein 698
HGHHNEPF_01310 1.5e-84 S NADPH-dependent FMN reductase
HGHHNEPF_01311 5.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGHHNEPF_01312 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HGHHNEPF_01313 2.6e-231 mntH P H( )-stimulated, divalent metal cation uptake system
HGHHNEPF_01314 6.5e-80 Q Methyltransferase
HGHHNEPF_01315 6.9e-116 ktrA P domain protein
HGHHNEPF_01316 5.8e-239 ktrB P Potassium uptake protein
HGHHNEPF_01317 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HGHHNEPF_01318 7.8e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HGHHNEPF_01319 2.2e-223 G Glycosyl hydrolases family 8
HGHHNEPF_01320 3.2e-242 ydaM M Glycosyl transferase
HGHHNEPF_01321 2.5e-134
HGHHNEPF_01322 3.3e-47 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HGHHNEPF_01323 9e-199 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HGHHNEPF_01325 1.1e-158 rssA S Phospholipase, patatin family
HGHHNEPF_01326 7.2e-118 L Integrase
HGHHNEPF_01327 2.7e-152 EG EamA-like transporter family
HGHHNEPF_01328 1.9e-129 narI 1.7.5.1 C Nitrate reductase
HGHHNEPF_01329 2.3e-99 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HGHHNEPF_01330 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HGHHNEPF_01331 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGHHNEPF_01332 7.2e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HGHHNEPF_01333 9.2e-81 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HGHHNEPF_01334 7.9e-227 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HGHHNEPF_01335 9.7e-83 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HGHHNEPF_01336 1.2e-103 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HGHHNEPF_01337 8.8e-44
HGHHNEPF_01338 7.4e-189 comP 2.7.13.3 F Sensor histidine kinase
HGHHNEPF_01339 2.3e-116 nreC K PFAM regulatory protein LuxR
HGHHNEPF_01340 1.6e-18
HGHHNEPF_01341 1.2e-180
HGHHNEPF_01342 8.4e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HGHHNEPF_01343 7.8e-219 narK P Transporter, major facilitator family protein
HGHHNEPF_01344 6.4e-35 moaD 2.8.1.12 H ThiS family
HGHHNEPF_01345 2.2e-64 moaE 2.8.1.12 H MoaE protein
HGHHNEPF_01346 7.8e-79 S Flavodoxin
HGHHNEPF_01347 8.3e-131 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGHHNEPF_01348 1.2e-138 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HGHHNEPF_01349 2.9e-182 fecB P Periplasmic binding protein
HGHHNEPF_01350 9.8e-180
HGHHNEPF_01351 7.8e-76
HGHHNEPF_01352 7.4e-83 S GIY-YIG catalytic domain
HGHHNEPF_01355 9.4e-141 IQ reductase
HGHHNEPF_01356 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
HGHHNEPF_01357 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HGHHNEPF_01358 2.3e-212 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGHHNEPF_01359 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HGHHNEPF_01360 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGHHNEPF_01361 3.6e-202 camS S sex pheromone
HGHHNEPF_01362 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGHHNEPF_01363 6.5e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HGHHNEPF_01364 2.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGHHNEPF_01365 5.3e-184 yegS 2.7.1.107 G Lipid kinase
HGHHNEPF_01366 3.6e-260 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGHHNEPF_01367 1.2e-32 S Domain of unknown function (DUF4417)
HGHHNEPF_01368 2.9e-19
HGHHNEPF_01369 3e-23
HGHHNEPF_01370 1.7e-15 K Helix-turn-helix domain
HGHHNEPF_01371 1.1e-23 E Zn peptidase
HGHHNEPF_01374 2.8e-13
HGHHNEPF_01376 4.6e-24
HGHHNEPF_01377 3.7e-97
HGHHNEPF_01378 6.4e-42
HGHHNEPF_01379 5.7e-19
HGHHNEPF_01380 1.9e-150 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HGHHNEPF_01381 8.3e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGHHNEPF_01382 1.7e-102 fic D Fic/DOC family
HGHHNEPF_01383 3.3e-71
HGHHNEPF_01384 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HGHHNEPF_01385 2.8e-96 L nuclease
HGHHNEPF_01386 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HGHHNEPF_01387 3.4e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HGHHNEPF_01388 7.9e-19 M Glycosyl hydrolases family 25
HGHHNEPF_01389 9.1e-144 ywqE 3.1.3.48 GM PHP domain protein
HGHHNEPF_01390 0.0 snf 2.7.11.1 KL domain protein
HGHHNEPF_01393 5e-249 mmuP E amino acid
HGHHNEPF_01394 4.4e-118 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HGHHNEPF_01395 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HGHHNEPF_01396 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HGHHNEPF_01397 5.5e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HGHHNEPF_01398 8.3e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGHHNEPF_01399 3.4e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGHHNEPF_01400 3e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGHHNEPF_01401 1.1e-62 rplQ J Ribosomal protein L17
HGHHNEPF_01402 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHHNEPF_01403 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGHHNEPF_01404 3.6e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGHHNEPF_01405 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HGHHNEPF_01406 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGHHNEPF_01407 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HGHHNEPF_01408 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HGHHNEPF_01409 8.9e-64 rplO J Binds to the 23S rRNA
HGHHNEPF_01410 2.9e-24 rpmD J Ribosomal protein L30
HGHHNEPF_01411 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGHHNEPF_01412 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGHHNEPF_01413 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGHHNEPF_01414 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGHHNEPF_01415 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGHHNEPF_01416 1.7e-48 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGHHNEPF_01417 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGHHNEPF_01418 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGHHNEPF_01419 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HGHHNEPF_01420 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HGHHNEPF_01421 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGHHNEPF_01422 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGHHNEPF_01423 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGHHNEPF_01424 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGHHNEPF_01425 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HGHHNEPF_01426 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HGHHNEPF_01427 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGHHNEPF_01428 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HGHHNEPF_01430 1e-91 L Integrase
HGHHNEPF_01431 3.3e-56 L Lactococcus lactis RepB C-terminus
HGHHNEPF_01432 2.4e-19 S Lysin motif
HGHHNEPF_01433 1.4e-102 L Replication initiation factor
HGHHNEPF_01434 9e-37 L Single-strand binding protein family
HGHHNEPF_01435 4.4e-83 L Phage integrase, N-terminal SAM-like domain
HGHHNEPF_01436 1.8e-10
HGHHNEPF_01440 1.1e-48 vsr L DNA mismatch endonuclease Vsr
HGHHNEPF_01441 3e-157 dcm 2.1.1.37 H cytosine-specific methyltransferase
HGHHNEPF_01442 6.6e-102 S NgoFVII restriction endonuclease
HGHHNEPF_01443 1.4e-14 S Helix-turn-helix domain
HGHHNEPF_01444 1.8e-42 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HGHHNEPF_01445 1e-182 arsB 1.20.4.1 P Sodium Bile acid symporter family
HGHHNEPF_01446 3.1e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGHHNEPF_01447 1.3e-52 cadX K Bacterial regulatory protein, arsR family
HGHHNEPF_01448 2.8e-95 cadD P Cadmium resistance transporter
HGHHNEPF_01450 1.9e-272 pipD E Dipeptidase
HGHHNEPF_01451 0.0 yjbQ P TrkA C-terminal domain protein
HGHHNEPF_01452 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HGHHNEPF_01453 6.2e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGHHNEPF_01454 1.9e-81
HGHHNEPF_01455 3.6e-35
HGHHNEPF_01456 1.3e-102 K DNA-templated transcription, initiation
HGHHNEPF_01457 8.5e-128
HGHHNEPF_01458 2.2e-69 K Transcriptional regulator, HxlR family
HGHHNEPF_01459 1.5e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HGHHNEPF_01460 2.7e-144 epsB M biosynthesis protein
HGHHNEPF_01461 3e-120 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HGHHNEPF_01462 1.7e-50 pglC M Bacterial sugar transferase
HGHHNEPF_01463 1.1e-87 GT4 G Glycosyl transferase 4-like
HGHHNEPF_01464 5.5e-40 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HGHHNEPF_01465 2.4e-127 3.2.1.23, 3.2.1.89 G arabinogalactan endo-1,4-beta-galactosidase activity
HGHHNEPF_01466 3.9e-63 gntR1 K Transcriptional regulator, GntR family
HGHHNEPF_01467 3.7e-154 V ABC transporter, ATP-binding protein
HGHHNEPF_01468 8.7e-114
HGHHNEPF_01469 2.3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HGHHNEPF_01470 4.9e-100 S Pfam:DUF3816
HGHHNEPF_01471 0.0 clpE O Belongs to the ClpA ClpB family
HGHHNEPF_01472 2.2e-27
HGHHNEPF_01473 4e-38 ptsH G phosphocarrier protein HPR
HGHHNEPF_01474 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGHHNEPF_01475 1.8e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HGHHNEPF_01476 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
HGHHNEPF_01477 1.1e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGHHNEPF_01478 2.8e-154 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGHHNEPF_01479 6e-08
HGHHNEPF_01481 1.1e-42 S Uncharacterised protein family (UPF0236)
HGHHNEPF_01482 3e-306 S AAA domain, putative AbiEii toxin, Type IV TA system
HGHHNEPF_01483 5.9e-205 3.6.4.12 L DNA helicase
HGHHNEPF_01484 2.7e-155
HGHHNEPF_01485 1.8e-17 QT PucR C-terminal helix-turn-helix domain
HGHHNEPF_01487 2.6e-26 S Protein of unknown function (DUF4065)
HGHHNEPF_01489 9.8e-21 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HGHHNEPF_01490 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HGHHNEPF_01491 6.8e-262 yfnA E amino acid
HGHHNEPF_01492 1.3e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HGHHNEPF_01493 3.8e-90 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGHHNEPF_01494 4.1e-40 ylqC S Belongs to the UPF0109 family
HGHHNEPF_01495 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HGHHNEPF_01496 1.3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGHHNEPF_01497 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HGHHNEPF_01498 9.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGHHNEPF_01499 0.0 smc D Required for chromosome condensation and partitioning
HGHHNEPF_01500 8e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HGHHNEPF_01501 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGHHNEPF_01502 2.2e-185 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HGHHNEPF_01503 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGHHNEPF_01504 0.0 yloV S DAK2 domain fusion protein YloV
HGHHNEPF_01505 4.7e-58 asp S Asp23 family, cell envelope-related function
HGHHNEPF_01506 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HGHHNEPF_01507 5.3e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HGHHNEPF_01508 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HGHHNEPF_01509 2.7e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HGHHNEPF_01510 0.0 KLT serine threonine protein kinase
HGHHNEPF_01511 3.8e-131 stp 3.1.3.16 T phosphatase
HGHHNEPF_01512 6.5e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGHHNEPF_01513 3.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGHHNEPF_01514 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGHHNEPF_01515 4.6e-211 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGHHNEPF_01516 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HGHHNEPF_01517 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HGHHNEPF_01518 1.4e-53
HGHHNEPF_01519 2.1e-262 recN L May be involved in recombinational repair of damaged DNA
HGHHNEPF_01520 5.6e-77 argR K Regulates arginine biosynthesis genes
HGHHNEPF_01521 4.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HGHHNEPF_01522 2.2e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGHHNEPF_01523 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGHHNEPF_01524 2.3e-227 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGHHNEPF_01525 1.2e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGHHNEPF_01526 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGHHNEPF_01527 2.2e-70 yqhY S Asp23 family, cell envelope-related function
HGHHNEPF_01528 8.9e-111 J 2'-5' RNA ligase superfamily
HGHHNEPF_01529 1.4e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HGHHNEPF_01530 3.8e-128 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HGHHNEPF_01531 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HGHHNEPF_01532 1.6e-54 ysxB J Cysteine protease Prp
HGHHNEPF_01533 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HGHHNEPF_01534 5.8e-112 K Transcriptional regulator
HGHHNEPF_01537 1.9e-86 dut S Protein conserved in bacteria
HGHHNEPF_01538 9.2e-176
HGHHNEPF_01539 1e-151
HGHHNEPF_01540 8.2e-51 S Iron-sulfur cluster assembly protein
HGHHNEPF_01541 4.2e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGHHNEPF_01542 6.6e-78 S Fic/DOC family
HGHHNEPF_01543 4.4e-51 E Filamentation induced by cAMP protein fic
HGHHNEPF_01546 2.5e-29
HGHHNEPF_01550 8e-38 M CHAP domain
HGHHNEPF_01552 3e-180 U type IV secretory pathway VirB4
HGHHNEPF_01553 8.1e-24
HGHHNEPF_01555 1e-64
HGHHNEPF_01556 3.5e-196 U TraM recognition site of TraD and TraG
HGHHNEPF_01561 6.7e-148 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HGHHNEPF_01563 3.8e-136 topA2 5.99.1.2 G Topoisomerase IA
HGHHNEPF_01564 9.1e-52 L Protein of unknown function (DUF3991)
HGHHNEPF_01566 4.3e-33 XK27_00515 D Glucan-binding protein C
HGHHNEPF_01567 1.4e-11 ftsZ D Cell surface antigen C-terminus
HGHHNEPF_01568 1e-23 sspC 2.7.7.7 DM Glucan-binding protein C
HGHHNEPF_01569 4.3e-92 L Belongs to the 'phage' integrase family
HGHHNEPF_01570 3.8e-48 S Domain of unknown function (DUF4393)
HGHHNEPF_01572 1.4e-33
HGHHNEPF_01573 4.1e-167 L restriction endonuclease
HGHHNEPF_01574 4.6e-94 mrr L restriction endonuclease
HGHHNEPF_01575 5.5e-21
HGHHNEPF_01576 0.0 L PLD-like domain
HGHHNEPF_01578 8.4e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HGHHNEPF_01579 7.8e-105 T Ion transport 2 domain protein
HGHHNEPF_01580 0.0 S Bacterial membrane protein YfhO
HGHHNEPF_01581 3.4e-206 G Transporter, major facilitator family protein
HGHHNEPF_01590 4.8e-58 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HGHHNEPF_01591 2e-18 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HGHHNEPF_01592 5.7e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HGHHNEPF_01593 2.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGHHNEPF_01594 3.7e-207 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HGHHNEPF_01595 2.3e-39 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HGHHNEPF_01596 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGHHNEPF_01597 1e-70 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HGHHNEPF_01598 5.9e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HGHHNEPF_01599 4.6e-129 IQ reductase
HGHHNEPF_01600 6.5e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HGHHNEPF_01601 5.5e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGHHNEPF_01602 7.8e-85 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGHHNEPF_01603 5.8e-81 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGHHNEPF_01604 4.2e-77 marR K Transcriptional regulator, MarR family
HGHHNEPF_01605 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGHHNEPF_01607 3.9e-201 xerS L Belongs to the 'phage' integrase family
HGHHNEPF_01608 2e-35 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HGHHNEPF_01610 7.2e-116 azlC E azaleucine resistance protein AzlC
HGHHNEPF_01611 3e-48 azlD E Branched-chain amino acid transport
HGHHNEPF_01612 8.3e-114 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HGHHNEPF_01614 7.2e-29 S GyrI-like small molecule binding domain
HGHHNEPF_01615 3.7e-47 S GyrI-like small molecule binding domain
HGHHNEPF_01616 8e-120 yhiD S MgtC family
HGHHNEPF_01617 6.2e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HGHHNEPF_01618 5.3e-192 V Beta-lactamase
HGHHNEPF_01619 5.3e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGHHNEPF_01620 4.5e-88 XK27_08850 J Aminoacyl-tRNA editing domain
HGHHNEPF_01621 3e-20 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HGHHNEPF_01622 8.6e-118 K LytTr DNA-binding domain
HGHHNEPF_01623 2.6e-196 2.7.13.3 T GHKL domain
HGHHNEPF_01625 3.1e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HGHHNEPF_01626 1.4e-222 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HGHHNEPF_01627 4.7e-288 S Psort location CytoplasmicMembrane, score
HGHHNEPF_01628 1.4e-164 yueF S AI-2E family transporter
HGHHNEPF_01629 8.9e-100 S dextransucrase activity
HGHHNEPF_01630 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HGHHNEPF_01631 0.0 lacS G Transporter
HGHHNEPF_01632 2.4e-184 lacR K Transcriptional regulator
HGHHNEPF_01633 6.6e-84
HGHHNEPF_01634 9.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
HGHHNEPF_01635 4.2e-53 S Mazg nucleotide pyrophosphohydrolase
HGHHNEPF_01636 3.4e-35
HGHHNEPF_01637 1.2e-51 M KxYKxGKxW signal domain protein
HGHHNEPF_01638 2.6e-137 3.2.1.96, 3.5.1.28 GH73 M repeat protein
HGHHNEPF_01639 2.2e-133 M repeat protein
HGHHNEPF_01640 3e-27
HGHHNEPF_01641 2.1e-177 M Glycosyltransferase like family 2
HGHHNEPF_01642 4.3e-95
HGHHNEPF_01644 4.9e-38 M Glycosyltransferase like family 2
HGHHNEPF_01645 8.8e-97 cps2J S Polysaccharide biosynthesis protein
HGHHNEPF_01646 5.5e-38 Z012_10770 M Domain of unknown function (DUF1919)
HGHHNEPF_01647 8.1e-196 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGHHNEPF_01649 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HGHHNEPF_01650 1.1e-181 L Helix-turn-helix domain
HGHHNEPF_01651 2.1e-214 L Transposase
HGHHNEPF_01652 2.6e-90 L Integrase
HGHHNEPF_01653 2.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HGHHNEPF_01654 3.3e-15 K Transcriptional regulator, LacI family
HGHHNEPF_01655 2.9e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HGHHNEPF_01656 6.3e-57 yitW S Pfam:DUF59
HGHHNEPF_01657 1.4e-77 L PFAM Integrase catalytic region
HGHHNEPF_01658 8.3e-78 L PFAM Integrase catalytic region
HGHHNEPF_01659 3.4e-266 pipD E Dipeptidase
HGHHNEPF_01660 8e-204 coiA 3.6.4.12 S Competence protein
HGHHNEPF_01661 1e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HGHHNEPF_01662 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HGHHNEPF_01663 2.3e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HGHHNEPF_01665 5.4e-77 L PFAM Integrase catalytic region
HGHHNEPF_01666 7.1e-109 yvrI K RNA polymerase sigma factor, sigma-70 family
HGHHNEPF_01667 2.6e-64 ydiI Q Thioesterase superfamily
HGHHNEPF_01668 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HGHHNEPF_01669 3.1e-267 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HGHHNEPF_01670 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HGHHNEPF_01671 4.2e-32 feoA P FeoA domain
HGHHNEPF_01672 3.2e-144 sufC O FeS assembly ATPase SufC
HGHHNEPF_01673 9.6e-239 sufD O FeS assembly protein SufD
HGHHNEPF_01674 3.1e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGHHNEPF_01675 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
HGHHNEPF_01676 2.3e-270 sufB O assembly protein SufB
HGHHNEPF_01677 4.7e-57 yitW S Iron-sulfur cluster assembly protein
HGHHNEPF_01678 4.4e-158 hipB K Helix-turn-helix
HGHHNEPF_01679 6.3e-100 nreC K PFAM regulatory protein LuxR
HGHHNEPF_01680 2.7e-38 S Cytochrome B5
HGHHNEPF_01681 1.7e-153 yitU 3.1.3.104 S hydrolase
HGHHNEPF_01682 3.8e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HGHHNEPF_01683 1.5e-147 f42a O Band 7 protein
HGHHNEPF_01684 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HGHHNEPF_01685 9.2e-130 lytT K response regulator receiver
HGHHNEPF_01686 1.9e-66 lrgA S LrgA family
HGHHNEPF_01687 2.2e-123 lrgB M LrgB-like family
HGHHNEPF_01688 2.1e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGHHNEPF_01689 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HGHHNEPF_01690 3.7e-185 galR K Periplasmic binding protein-like domain
HGHHNEPF_01691 0.0 rafA 3.2.1.22 G alpha-galactosidase
HGHHNEPF_01692 4.9e-87 S Protein of unknown function (DUF1440)
HGHHNEPF_01693 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HGHHNEPF_01694 2.1e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HGHHNEPF_01695 1.1e-165 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HGHHNEPF_01696 5.3e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HGHHNEPF_01697 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HGHHNEPF_01698 4.9e-85 ypmB S Protein conserved in bacteria
HGHHNEPF_01699 2.8e-123 dnaD L DnaD domain protein
HGHHNEPF_01700 1.3e-160 EG EamA-like transporter family
HGHHNEPF_01701 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HGHHNEPF_01702 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HGHHNEPF_01703 1.7e-102 ypsA S Belongs to the UPF0398 family
HGHHNEPF_01704 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HGHHNEPF_01705 1.1e-83 F Belongs to the NrdI family
HGHHNEPF_01706 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HGHHNEPF_01707 4e-71 rnhA 3.1.26.4 L Ribonuclease HI
HGHHNEPF_01708 1.5e-65 esbA S Family of unknown function (DUF5322)
HGHHNEPF_01709 7.7e-71 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGHHNEPF_01710 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGHHNEPF_01711 3.1e-206 carA 6.3.5.5 F Belongs to the CarA family
HGHHNEPF_01712 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HGHHNEPF_01713 0.0 FbpA K Fibronectin-binding protein
HGHHNEPF_01714 6.4e-162 degV S EDD domain protein, DegV family
HGHHNEPF_01715 9.4e-94
HGHHNEPF_01716 5e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGHHNEPF_01717 5.5e-158 gspA M family 8
HGHHNEPF_01718 1.7e-159 S Alpha beta hydrolase
HGHHNEPF_01719 1.8e-95 K Acetyltransferase (GNAT) domain
HGHHNEPF_01720 1.4e-148 XK27_08635 S UPF0210 protein
HGHHNEPF_01721 2.6e-80 XK27_08635 S UPF0210 protein
HGHHNEPF_01722 1.4e-38 gcvR T Belongs to the UPF0237 family
HGHHNEPF_01723 1.2e-152 1.1.1.346 C Aldo keto reductase
HGHHNEPF_01724 3.9e-63 K Transcriptional regulator
HGHHNEPF_01725 3.3e-76 yphH S Cupin domain
HGHHNEPF_01726 1.9e-72 yeaL S UPF0756 membrane protein
HGHHNEPF_01727 3.3e-245 EGP Major facilitator Superfamily
HGHHNEPF_01728 5e-75 copY K Copper transport repressor CopY TcrY
HGHHNEPF_01729 1.9e-245 yhdP S Transporter associated domain
HGHHNEPF_01730 0.0 ubiB S ABC1 family
HGHHNEPF_01731 2.5e-136 S DUF218 domain
HGHHNEPF_01732 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGHHNEPF_01733 0.0 uvrA3 L excinuclease ABC, A subunit
HGHHNEPF_01734 5.1e-122 S SNARE associated Golgi protein
HGHHNEPF_01735 1.2e-230 N Uncharacterized conserved protein (DUF2075)
HGHHNEPF_01736 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGHHNEPF_01738 3e-254 yifK E Amino acid permease
HGHHNEPF_01739 1.1e-150 endA V DNA/RNA non-specific endonuclease
HGHHNEPF_01740 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGHHNEPF_01741 1.3e-41 ybaN S Protein of unknown function (DUF454)
HGHHNEPF_01742 5.9e-71 S Protein of unknown function (DUF3290)
HGHHNEPF_01743 4.7e-114 yviA S Protein of unknown function (DUF421)
HGHHNEPF_01744 3.7e-91 S Alpha/beta hydrolase of unknown function (DUF915)
HGHHNEPF_01745 1.1e-39 S Alpha/beta hydrolase of unknown function (DUF915)
HGHHNEPF_01746 3.4e-21
HGHHNEPF_01747 3.6e-90 ntd 2.4.2.6 F Nucleoside
HGHHNEPF_01748 3.1e-150 3.1.3.102, 3.1.3.104 S hydrolase
HGHHNEPF_01749 1.4e-46 yrvD S Pfam:DUF1049
HGHHNEPF_01751 6.7e-164 I alpha/beta hydrolase fold
HGHHNEPF_01752 3.5e-112 frnE Q DSBA-like thioredoxin domain
HGHHNEPF_01753 8.9e-54
HGHHNEPF_01754 4e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HGHHNEPF_01755 5.6e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGHHNEPF_01756 1.2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
HGHHNEPF_01757 1.2e-114 yjbH Q Thioredoxin
HGHHNEPF_01758 1.3e-40 L PFAM Integrase catalytic region
HGHHNEPF_01759 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HGHHNEPF_01760 6.2e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HGHHNEPF_01761 3.8e-49 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGHHNEPF_01762 1.4e-50
HGHHNEPF_01763 0.0 S SEC-C Motif Domain Protein
HGHHNEPF_01764 5.8e-115 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HGHHNEPF_01765 3.5e-46 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain protein
HGHHNEPF_01766 8.9e-178 L Belongs to the 'phage' integrase family
HGHHNEPF_01767 1.1e-45 3.1.21.3 V Type I restriction modification DNA specificity domain
HGHHNEPF_01768 5.3e-283 O Arylsulfotransferase (ASST)
HGHHNEPF_01788 5.7e-140 L PFAM transposase IS116 IS110 IS902
HGHHNEPF_01789 8.7e-140 L hmm pf00665
HGHHNEPF_01790 7.2e-96 L Helix-turn-helix domain
HGHHNEPF_01791 2.8e-260 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HGHHNEPF_01792 5e-192 hsdM 2.1.1.72 V type I restriction-modification system
HGHHNEPF_01793 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HGHHNEPF_01794 1.3e-14 IQ KR domain
HGHHNEPF_01795 1.6e-24
HGHHNEPF_01796 3.3e-54 yhaI S Protein of unknown function (DUF805)
HGHHNEPF_01797 5e-44
HGHHNEPF_01798 0.0 nylA 3.5.1.4 J Belongs to the amidase family
HGHHNEPF_01799 4.8e-23
HGHHNEPF_01800 5.4e-47
HGHHNEPF_01801 3.2e-95 K Acetyltransferase (GNAT) domain
HGHHNEPF_01802 2.5e-294 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HGHHNEPF_01803 2.4e-232 gntT EG Gluconate
HGHHNEPF_01804 1.2e-183 K Transcriptional regulator, LacI family
HGHHNEPF_01805 4.9e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HGHHNEPF_01806 8.5e-96
HGHHNEPF_01807 2.1e-25
HGHHNEPF_01808 1.3e-61 asp S Asp23 family, cell envelope-related function
HGHHNEPF_01809 1.8e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HGHHNEPF_01811 6e-49
HGHHNEPF_01812 1.1e-68 yqkB S Belongs to the HesB IscA family
HGHHNEPF_01813 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HGHHNEPF_01814 5.4e-83 F NUDIX domain
HGHHNEPF_01815 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGHHNEPF_01816 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGHHNEPF_01817 9.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HGHHNEPF_01818 7.9e-168 lacX 5.1.3.3 G Aldose 1-epimerase
HGHHNEPF_01819 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGHHNEPF_01820 7.8e-160 dprA LU DNA protecting protein DprA
HGHHNEPF_01821 7.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGHHNEPF_01822 8.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HGHHNEPF_01823 1.7e-34 yozE S Belongs to the UPF0346 family
HGHHNEPF_01824 1.3e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HGHHNEPF_01825 2.6e-169 ypmR E lipolytic protein G-D-S-L family
HGHHNEPF_01826 6.4e-151 DegV S EDD domain protein, DegV family
HGHHNEPF_01827 1.7e-111 hlyIII S protein, hemolysin III
HGHHNEPF_01828 1.1e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HGHHNEPF_01829 2.5e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGHHNEPF_01830 0.0 yfmR S ABC transporter, ATP-binding protein
HGHHNEPF_01831 1.8e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HGHHNEPF_01832 1.5e-236 S Tetratricopeptide repeat protein
HGHHNEPF_01833 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HGHHNEPF_01834 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HGHHNEPF_01835 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HGHHNEPF_01836 3.9e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HGHHNEPF_01837 8.5e-14 M Lysin motif
HGHHNEPF_01838 6.2e-263 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HGHHNEPF_01839 3e-187 ypbB 5.1.3.1 S Helix-turn-helix domain
HGHHNEPF_01840 5.8e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HGHHNEPF_01842 1.7e-173 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HGHHNEPF_01843 8.2e-58 hol S COG5546 Small integral membrane protein
HGHHNEPF_01844 2.3e-27
HGHHNEPF_01848 9.4e-163
HGHHNEPF_01849 6.8e-23 S GDSL-like Lipase/Acylhydrolase
HGHHNEPF_01852 2.8e-14 tcdA2 GT2,GT4 LM gp58-like protein
HGHHNEPF_01853 1.8e-201 M Prophage endopeptidase tail
HGHHNEPF_01854 3.1e-113 S Phage tail protein
HGHHNEPF_01855 5.8e-224 M Phage tail tape measure protein TP901
HGHHNEPF_01856 1.6e-19
HGHHNEPF_01857 1.2e-65 S Phage tail tube protein
HGHHNEPF_01858 5.7e-25
HGHHNEPF_01859 1.3e-20
HGHHNEPF_01860 4e-38 S Phage head-tail joining protein
HGHHNEPF_01861 1.8e-43 S Phage gp6-like head-tail connector protein
HGHHNEPF_01862 1.5e-131 S Phage capsid family
HGHHNEPF_01863 1.7e-88 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HGHHNEPF_01864 4.9e-145 S portal protein
HGHHNEPF_01866 1.4e-267 S Phage Terminase
HGHHNEPF_01867 4.2e-80 L Phage terminase, small subunit
HGHHNEPF_01868 4.3e-50 L HNH nucleases
HGHHNEPF_01882 7.7e-205 S Uncharacterised protein family (UPF0236)
HGHHNEPF_01892 1.4e-44 S RelE-like toxin of type II toxin-antitoxin system HigB
HGHHNEPF_01893 4.4e-38 higA K Helix-turn-helix XRE-family like proteins
HGHHNEPF_01894 3.4e-186 L Transposase
HGHHNEPF_01895 7.7e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGHHNEPF_01898 9.8e-112 yvyE 3.4.13.9 S YigZ family
HGHHNEPF_01899 1e-113 L PFAM Integrase catalytic region
HGHHNEPF_01900 6.4e-42 L PFAM Integrase catalytic region
HGHHNEPF_01901 8.1e-151 L PFAM Integrase catalytic region
HGHHNEPF_01902 9.7e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HGHHNEPF_01903 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGHHNEPF_01904 4.4e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HGHHNEPF_01905 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGHHNEPF_01906 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HGHHNEPF_01907 7.2e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HGHHNEPF_01908 9.8e-67 yabR J RNA binding
HGHHNEPF_01909 6.6e-57 divIC D Septum formation initiator
HGHHNEPF_01910 2.1e-39 yabO J S4 domain protein
HGHHNEPF_01911 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGHHNEPF_01912 5.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HGHHNEPF_01913 6.9e-113 S (CBS) domain
HGHHNEPF_01914 2e-146 tesE Q hydratase
HGHHNEPF_01915 9.8e-241 codA 3.5.4.1 F cytosine deaminase
HGHHNEPF_01916 4.4e-250 U Belongs to the purine-cytosine permease (2.A.39) family
HGHHNEPF_01917 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
HGHHNEPF_01918 8.7e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGHHNEPF_01919 1.9e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HGHHNEPF_01921 8e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGHHNEPF_01922 1.3e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
HGHHNEPF_01923 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGHHNEPF_01924 2.2e-251 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HGHHNEPF_01925 1.4e-164 glsA 3.5.1.2 E Belongs to the glutaminase family
HGHHNEPF_01926 0.0 sprD D Domain of Unknown Function (DUF1542)
HGHHNEPF_01927 5.3e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HGHHNEPF_01928 2.6e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HGHHNEPF_01929 1.5e-158 htpX O Belongs to the peptidase M48B family
HGHHNEPF_01930 3.5e-92 lemA S LemA family
HGHHNEPF_01931 2.3e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGHHNEPF_01932 1.2e-120 pgm3 G Belongs to the phosphoglycerate mutase family
HGHHNEPF_01933 2.6e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HGHHNEPF_01934 4.4e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGHHNEPF_01935 2.5e-124 srtA 3.4.22.70 M sortase family
HGHHNEPF_01936 6.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HGHHNEPF_01937 5.7e-239 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGHHNEPF_01938 4.6e-41 rpmE2 J Ribosomal protein L31
HGHHNEPF_01939 4e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGHHNEPF_01940 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HGHHNEPF_01941 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HGHHNEPF_01942 3e-66 ywiB S Domain of unknown function (DUF1934)
HGHHNEPF_01943 3.9e-145 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HGHHNEPF_01944 3.8e-270 ywfO S HD domain protein
HGHHNEPF_01945 8.4e-148 yxeH S hydrolase
HGHHNEPF_01946 2.6e-47
HGHHNEPF_01947 3.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGHHNEPF_01948 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGHHNEPF_01949 6.5e-148 purR 2.4.2.7 F pur operon repressor
HGHHNEPF_01950 4.7e-119 znuB U ABC 3 transport family
HGHHNEPF_01951 3.8e-122 fhuC P ABC transporter
HGHHNEPF_01952 3.3e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
HGHHNEPF_01953 7.6e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGHHNEPF_01954 6.8e-37 veg S Biofilm formation stimulator VEG
HGHHNEPF_01955 1.9e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HGHHNEPF_01956 3.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HGHHNEPF_01957 2.4e-155 tatD L hydrolase, TatD family
HGHHNEPF_01958 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGHHNEPF_01959 8.1e-162 yunF F Protein of unknown function DUF72
HGHHNEPF_01961 8.8e-130 cobB K SIR2 family
HGHHNEPF_01962 1.1e-175
HGHHNEPF_01963 1.5e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HGHHNEPF_01964 1.8e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGHHNEPF_01965 2.9e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGHHNEPF_01966 4.8e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HGHHNEPF_01967 8.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
HGHHNEPF_01968 0.0 helD 3.6.4.12 L DNA helicase
HGHHNEPF_01969 1.3e-202 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HGHHNEPF_01970 1.9e-197 clcA P chloride
HGHHNEPF_01971 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
HGHHNEPF_01972 3.1e-110 L PFAM Integrase catalytic region
HGHHNEPF_01973 2.2e-29 L Helix-turn-helix domain
HGHHNEPF_01974 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGHHNEPF_01975 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGHHNEPF_01976 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HGHHNEPF_01977 2.2e-145 holA 2.7.7.7 L DNA polymerase III delta subunit
HGHHNEPF_01978 0.0 comEC S Competence protein ComEC
HGHHNEPF_01979 1.2e-88 comEB 3.5.4.12 F ComE operon protein 2
HGHHNEPF_01980 4.6e-77 comEA L Competence protein ComEA
HGHHNEPF_01981 7.1e-200 ylbL T Belongs to the peptidase S16 family
HGHHNEPF_01982 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGHHNEPF_01983 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HGHHNEPF_01984 1.1e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HGHHNEPF_01985 1.1e-223 ftsW D Belongs to the SEDS family
HGHHNEPF_01986 0.0 typA T GTP-binding protein TypA
HGHHNEPF_01987 3.5e-135 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HGHHNEPF_01988 1.5e-46 yktA S Belongs to the UPF0223 family
HGHHNEPF_01989 5.4e-275 lpdA 1.8.1.4 C Dehydrogenase
HGHHNEPF_01990 2.3e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGHHNEPF_01991 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HGHHNEPF_01992 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HGHHNEPF_01993 3.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGHHNEPF_01994 3.6e-82
HGHHNEPF_01995 9.8e-32 ykzG S Belongs to the UPF0356 family
HGHHNEPF_01996 6.7e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HGHHNEPF_01997 5.7e-29
HGHHNEPF_01998 1.7e-127 mltD CBM50 M NlpC P60 family protein
HGHHNEPF_02000 7.7e-58
HGHHNEPF_02001 5.6e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HGHHNEPF_02002 9.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGHHNEPF_02003 3.8e-218 patA 2.6.1.1 E Aminotransferase
HGHHNEPF_02004 5e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HGHHNEPF_02005 5.9e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGHHNEPF_02006 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HGHHNEPF_02007 6.7e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HGHHNEPF_02008 5e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HGHHNEPF_02009 1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HGHHNEPF_02010 8.6e-187 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGHHNEPF_02011 1.2e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGHHNEPF_02012 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HGHHNEPF_02013 9e-119 S Repeat protein
HGHHNEPF_02014 8.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HGHHNEPF_02015 3.4e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HGHHNEPF_02016 2.8e-57 XK27_04120 S Putative amino acid metabolism
HGHHNEPF_02017 2.1e-216 iscS 2.8.1.7 E Aminotransferase class V
HGHHNEPF_02018 1.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGHHNEPF_02020 3.2e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HGHHNEPF_02021 4.2e-32 cspA K Cold shock protein
HGHHNEPF_02022 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGHHNEPF_02023 1.9e-42 divIVA D DivIVA domain protein
HGHHNEPF_02024 1.2e-140 ylmH S S4 domain protein
HGHHNEPF_02025 3.2e-40 yggT S YGGT family
HGHHNEPF_02026 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HGHHNEPF_02027 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGHHNEPF_02028 1.2e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HGHHNEPF_02029 5.1e-140 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HGHHNEPF_02030 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGHHNEPF_02031 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGHHNEPF_02032 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGHHNEPF_02033 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HGHHNEPF_02034 1.5e-56 ftsL D Cell division protein FtsL
HGHHNEPF_02035 3.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HGHHNEPF_02036 1.5e-76 mraZ K Belongs to the MraZ family
HGHHNEPF_02037 5e-57
HGHHNEPF_02038 1.2e-10 S Protein of unknown function (DUF4044)
HGHHNEPF_02039 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HGHHNEPF_02040 5.7e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HGHHNEPF_02041 2.9e-159 rrmA 2.1.1.187 H Methyltransferase
HGHHNEPF_02042 7.8e-183 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HGHHNEPF_02044 9.2e-52 XK27_01125 L PFAM IS66 Orf2 family protein
HGHHNEPF_02045 1.4e-292 L Transposase IS66 family
HGHHNEPF_02047 2e-48 L PFAM transposase IS200-family protein
HGHHNEPF_02048 4.4e-77 uspA T universal stress protein
HGHHNEPF_02049 3.3e-80 K AsnC family
HGHHNEPF_02050 2e-231 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGHHNEPF_02051 2.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
HGHHNEPF_02052 5e-179 galR K Transcriptional regulator
HGHHNEPF_02053 3.8e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HGHHNEPF_02054 2.9e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HGHHNEPF_02055 2.1e-177 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HGHHNEPF_02056 4.9e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
HGHHNEPF_02057 2e-91 yxkA S Phosphatidylethanolamine-binding protein
HGHHNEPF_02058 9.1e-36
HGHHNEPF_02059 2.6e-52
HGHHNEPF_02060 1e-204
HGHHNEPF_02061 2.9e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGHHNEPF_02062 1.2e-135 pnuC H nicotinamide mononucleotide transporter
HGHHNEPF_02063 7.8e-157 ytbE 1.1.1.346 S Aldo keto reductase
HGHHNEPF_02064 4.1e-124 K response regulator
HGHHNEPF_02065 5.5e-178 T PhoQ Sensor
HGHHNEPF_02066 1.1e-133 macB2 V ABC transporter, ATP-binding protein
HGHHNEPF_02067 0.0 ysaB V FtsX-like permease family
HGHHNEPF_02068 1.7e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HGHHNEPF_02069 2.7e-166 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGHHNEPF_02070 6.7e-53 K helix_turn_helix, mercury resistance
HGHHNEPF_02071 6.6e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGHHNEPF_02072 2.4e-193 EGP Major facilitator Superfamily
HGHHNEPF_02073 2.5e-86 ymdB S Macro domain protein
HGHHNEPF_02074 1.2e-109 K Helix-turn-helix domain
HGHHNEPF_02075 0.0 pepO 3.4.24.71 O Peptidase family M13
HGHHNEPF_02076 4.6e-48
HGHHNEPF_02077 4.6e-233 S Putative metallopeptidase domain
HGHHNEPF_02078 5.6e-206 3.1.3.1 S associated with various cellular activities
HGHHNEPF_02079 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HGHHNEPF_02080 5.4e-65 yeaO S Protein of unknown function, DUF488
HGHHNEPF_02082 1.2e-115 yrkL S Flavodoxin-like fold
HGHHNEPF_02083 3.6e-54
HGHHNEPF_02084 1.5e-18 S Domain of unknown function (DUF4767)
HGHHNEPF_02085 2.9e-136 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HGHHNEPF_02086 3.1e-49
HGHHNEPF_02087 1.6e-199 nrnB S DHHA1 domain
HGHHNEPF_02088 6e-230 S Uncharacterized protein conserved in bacteria (DUF2325)
HGHHNEPF_02089 2.2e-249 brnQ U Component of the transport system for branched-chain amino acids
HGHHNEPF_02090 1.3e-105 NU mannosyl-glycoprotein
HGHHNEPF_02091 1.6e-143 S Putative ABC-transporter type IV
HGHHNEPF_02092 1.7e-274 S ABC transporter, ATP-binding protein
HGHHNEPF_02093 4.1e-10
HGHHNEPF_02095 5.1e-105 S Protein of unknown function (DUF3278)
HGHHNEPF_02097 7e-75 M PFAM NLP P60 protein
HGHHNEPF_02098 9.8e-183 ABC-SBP S ABC transporter
HGHHNEPF_02099 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HGHHNEPF_02100 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
HGHHNEPF_02101 8.8e-96 P Cadmium resistance transporter
HGHHNEPF_02102 2.4e-56 K Transcriptional regulator, ArsR family
HGHHNEPF_02103 3.2e-55 trxA O Belongs to the thioredoxin family
HGHHNEPF_02104 2.3e-131 terC P membrane
HGHHNEPF_02105 1.8e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGHHNEPF_02106 2.4e-167 corA P CorA-like Mg2+ transporter protein
HGHHNEPF_02107 2e-282 pipD E Dipeptidase
HGHHNEPF_02108 5.6e-242 pbuX F xanthine permease
HGHHNEPF_02109 2.4e-251 nhaC C Na H antiporter NhaC
HGHHNEPF_02110 2.4e-284 S C4-dicarboxylate anaerobic carrier
HGHHNEPF_02111 7.2e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
HGHHNEPF_02112 1.3e-41
HGHHNEPF_02113 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HGHHNEPF_02114 3.4e-35 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HGHHNEPF_02115 7.8e-109 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HGHHNEPF_02116 4.6e-156 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HGHHNEPF_02117 3.8e-35
HGHHNEPF_02118 1.7e-162 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HGHHNEPF_02119 1e-12 ydiN 5.4.99.5 G Major Facilitator
HGHHNEPF_02120 6.5e-54 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HGHHNEPF_02121 5.1e-127 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGHHNEPF_02122 7.4e-132 ydiN G Major Facilitator Superfamily
HGHHNEPF_02125 5.1e-60 yfbR S HD containing hydrolase-like enzyme
HGHHNEPF_02126 2.2e-36 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HGHHNEPF_02130 5.9e-214 uhpT EGP Major facilitator Superfamily
HGHHNEPF_02131 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HGHHNEPF_02132 1e-129 ponA V Beta-lactamase enzyme family
HGHHNEPF_02133 3.8e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HGHHNEPF_02134 4.3e-74
HGHHNEPF_02135 7e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HGHHNEPF_02136 8.1e-28
HGHHNEPF_02137 7.6e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
HGHHNEPF_02138 9.5e-294 L PFAM plasmid pRiA4b ORF-3 family protein
HGHHNEPF_02139 1.9e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HGHHNEPF_02140 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGHHNEPF_02141 1.2e-160 mleR K LysR family
HGHHNEPF_02142 2.9e-309 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HGHHNEPF_02143 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HGHHNEPF_02144 3.6e-268 frdC 1.3.5.4 C FAD binding domain
HGHHNEPF_02145 4.9e-252 yflS P Sodium:sulfate symporter transmembrane region
HGHHNEPF_02146 6.3e-157 mleR K LysR family
HGHHNEPF_02147 1.2e-250 yjjP S Putative threonine/serine exporter
HGHHNEPF_02148 1.9e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
HGHHNEPF_02149 1.4e-270 emrY EGP Major facilitator Superfamily
HGHHNEPF_02150 3.3e-183 I Alpha beta
HGHHNEPF_02151 1.2e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HGHHNEPF_02152 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGHHNEPF_02154 1.2e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HGHHNEPF_02155 1e-120 S Domain of unknown function (DUF4811)
HGHHNEPF_02156 3.6e-269 lmrB EGP Major facilitator Superfamily
HGHHNEPF_02157 5.2e-75 merR K MerR HTH family regulatory protein
HGHHNEPF_02158 7.2e-56
HGHHNEPF_02159 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGHHNEPF_02160 1.6e-216 S CAAX protease self-immunity
HGHHNEPF_02161 6.1e-109 glnP P ABC transporter permease
HGHHNEPF_02162 3.2e-110 gluC P ABC transporter permease
HGHHNEPF_02163 2.2e-151 glnH ET ABC transporter
HGHHNEPF_02164 5.3e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGHHNEPF_02165 5.5e-83 usp1 T Belongs to the universal stress protein A family
HGHHNEPF_02166 7.6e-110 S VIT family
HGHHNEPF_02167 1.7e-117 S membrane
HGHHNEPF_02168 3.5e-166 czcD P cation diffusion facilitator family transporter
HGHHNEPF_02169 2e-123 sirR K iron dependent repressor
HGHHNEPF_02170 7.9e-31 cspC K Cold shock protein
HGHHNEPF_02171 2.1e-129 thrE S Putative threonine/serine exporter
HGHHNEPF_02172 3e-81 S Threonine/Serine exporter, ThrE
HGHHNEPF_02173 2.3e-119 lssY 3.6.1.27 I phosphatase
HGHHNEPF_02174 5.4e-11 2.3.1.128 J Acetyltransferase (GNAT) domain
HGHHNEPF_02175 1.1e-275 lysP E amino acid
HGHHNEPF_02176 5.6e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HGHHNEPF_02182 4.7e-12
HGHHNEPF_02183 1.7e-179 S Hydrolases of the alpha beta superfamily
HGHHNEPF_02184 2.7e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HGHHNEPF_02185 1.7e-76 ctsR K Belongs to the CtsR family
HGHHNEPF_02186 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HGHHNEPF_02187 1e-110 K Bacterial regulatory proteins, tetR family
HGHHNEPF_02188 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHHNEPF_02189 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGHHNEPF_02190 2.2e-202 ykiI
HGHHNEPF_02191 5.7e-118 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HGHHNEPF_02192 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGHHNEPF_02193 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HGHHNEPF_02194 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGHHNEPF_02195 1.3e-162 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGHHNEPF_02196 1.9e-30 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)