ORF_ID e_value Gene_name EC_number CAZy COGs Description
NNMPHLEP_00001 4.1e-281 yjeM E Amino Acid
NNMPHLEP_00002 5.8e-150 yihY S Belongs to the UPF0761 family
NNMPHLEP_00003 9.5e-33 S Protein of unknown function (DUF2922)
NNMPHLEP_00004 4.9e-31
NNMPHLEP_00005 1.1e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
NNMPHLEP_00006 1.3e-145 cps1D M Domain of unknown function (DUF4422)
NNMPHLEP_00007 1e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NNMPHLEP_00008 4.2e-118 rfbP 2.7.8.6 M Bacterial sugar transferase
NNMPHLEP_00009 0.0 2.7.7.6 M Peptidase family M23
NNMPHLEP_00010 0.0 G Peptidase_C39 like family
NNMPHLEP_00011 1.8e-24
NNMPHLEP_00012 1.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
NNMPHLEP_00013 2.3e-209 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NNMPHLEP_00014 2.3e-75 M transferase activity, transferring glycosyl groups
NNMPHLEP_00015 4.5e-89 cps3F
NNMPHLEP_00016 8.7e-28 M biosynthesis protein
NNMPHLEP_00017 6.9e-77 rgpB GT2 M Glycosyl transferase family 2
NNMPHLEP_00018 4.4e-66 S Glycosyltransferase like family
NNMPHLEP_00019 2.2e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
NNMPHLEP_00020 1.4e-81
NNMPHLEP_00021 2.9e-144 rfbJ M Glycosyl transferase family 2
NNMPHLEP_00022 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNMPHLEP_00024 6e-160 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NNMPHLEP_00025 2.3e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NNMPHLEP_00026 7.1e-200 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NNMPHLEP_00027 5.8e-152 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NNMPHLEP_00028 3.4e-263 G Peptidase_C39 like family
NNMPHLEP_00029 2e-163 yueF S AI-2E family transporter
NNMPHLEP_00030 5.8e-224 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NNMPHLEP_00031 7.4e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NNMPHLEP_00032 0.0 M NlpC/P60 family
NNMPHLEP_00033 6.2e-76 S Peptidase, M23
NNMPHLEP_00034 0.0 S Peptidase, M23
NNMPHLEP_00035 2.7e-64 gntR1 K Transcriptional regulator, GntR family
NNMPHLEP_00036 1.4e-156 V ABC transporter, ATP-binding protein
NNMPHLEP_00037 2.3e-114
NNMPHLEP_00038 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NNMPHLEP_00039 1.6e-98 S Pfam:DUF3816
NNMPHLEP_00040 0.0 clpE O Belongs to the ClpA ClpB family
NNMPHLEP_00041 6.4e-27
NNMPHLEP_00042 2.7e-39 ptsH G phosphocarrier protein HPR
NNMPHLEP_00043 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NNMPHLEP_00044 6.7e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NNMPHLEP_00045 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
NNMPHLEP_00046 5.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNMPHLEP_00047 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
NNMPHLEP_00050 4.6e-72 L Integrase core domain
NNMPHLEP_00051 2.7e-230 S amidohydrolase
NNMPHLEP_00052 1.3e-25 S amidohydrolase
NNMPHLEP_00053 1.1e-55 K LysR substrate binding domain
NNMPHLEP_00055 1.9e-07 yiiE S Protein of unknown function (DUF1211)
NNMPHLEP_00057 9.1e-161 S reductase
NNMPHLEP_00058 4.8e-90 2.3.1.183 M Acetyltransferase GNAT family
NNMPHLEP_00059 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NNMPHLEP_00060 4.1e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
NNMPHLEP_00061 9.9e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NNMPHLEP_00062 0.0 asnB 6.3.5.4 E Asparagine synthase
NNMPHLEP_00063 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NNMPHLEP_00064 6.9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NNMPHLEP_00065 5.1e-131 jag S R3H domain protein
NNMPHLEP_00066 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNMPHLEP_00067 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NNMPHLEP_00068 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NNMPHLEP_00069 1.9e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NNMPHLEP_00070 8e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NNMPHLEP_00071 1.7e-34 yaaA S S4 domain protein YaaA
NNMPHLEP_00072 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NNMPHLEP_00073 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNMPHLEP_00074 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NNMPHLEP_00075 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NNMPHLEP_00076 6.3e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NNMPHLEP_00077 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NNMPHLEP_00078 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NNMPHLEP_00079 4.4e-74 rplI J Binds to the 23S rRNA
NNMPHLEP_00080 6.9e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NNMPHLEP_00081 9e-207 yttB EGP Major facilitator Superfamily
NNMPHLEP_00082 5.7e-55
NNMPHLEP_00083 2.1e-197 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NNMPHLEP_00084 8.2e-247 aldA 1.2.1.21, 1.2.1.22 C Belongs to the aldehyde dehydrogenase family
NNMPHLEP_00085 4.3e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
NNMPHLEP_00086 1.3e-123 Z012_01130 S Fic/DOC family
NNMPHLEP_00088 2.1e-73 K helix_turn_helix multiple antibiotic resistance protein
NNMPHLEP_00089 2.8e-47 lmrA 3.6.3.44 V ABC transporter
NNMPHLEP_00090 2.2e-165 lmrA 3.6.3.44 V ABC transporter
NNMPHLEP_00092 5.2e-130 K response regulator
NNMPHLEP_00093 0.0 vicK 2.7.13.3 T Histidine kinase
NNMPHLEP_00094 1.5e-247 yycH S YycH protein
NNMPHLEP_00095 7.8e-149 yycI S YycH protein
NNMPHLEP_00096 2.3e-153 vicX 3.1.26.11 S domain protein
NNMPHLEP_00097 7.3e-215 htrA 3.4.21.107 O serine protease
NNMPHLEP_00098 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NNMPHLEP_00099 3.9e-20 ABC-SBP S ABC transporter
NNMPHLEP_00100 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NNMPHLEP_00101 3.2e-95 S reductase
NNMPHLEP_00102 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NNMPHLEP_00103 7.5e-155 glcU U sugar transport
NNMPHLEP_00104 1.2e-148 E Glyoxalase-like domain
NNMPHLEP_00105 6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNMPHLEP_00106 2e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NNMPHLEP_00107 4.4e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NNMPHLEP_00108 4.4e-129 V ABC transporter
NNMPHLEP_00109 2.6e-217 bacI V MacB-like periplasmic core domain
NNMPHLEP_00111 1.3e-37
NNMPHLEP_00112 2.4e-256 S Putative peptidoglycan binding domain
NNMPHLEP_00115 3.9e-30 2.7.13.3 T GHKL domain
NNMPHLEP_00116 6.2e-135 2.7.13.3 T GHKL domain
NNMPHLEP_00117 1.1e-136 K LytTr DNA-binding domain
NNMPHLEP_00121 1.3e-245 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NNMPHLEP_00123 8.5e-75 osmC O OsmC-like protein
NNMPHLEP_00124 7.3e-178 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNMPHLEP_00125 8.9e-215 patA 2.6.1.1 E Aminotransferase
NNMPHLEP_00126 2.3e-81 lytE M LysM domain protein
NNMPHLEP_00127 0.0 oppD EP Psort location Cytoplasmic, score
NNMPHLEP_00128 2.2e-93 lytE M LysM domain protein
NNMPHLEP_00129 4.9e-150 xth 3.1.11.2 L exodeoxyribonuclease III
NNMPHLEP_00130 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NNMPHLEP_00131 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
NNMPHLEP_00132 9e-153 yeaE S Aldo keto
NNMPHLEP_00133 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
NNMPHLEP_00134 3.1e-281 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NNMPHLEP_00135 1.3e-78 S Psort location Cytoplasmic, score
NNMPHLEP_00136 2.9e-85 S Short repeat of unknown function (DUF308)
NNMPHLEP_00137 1e-23
NNMPHLEP_00138 9.7e-103 V VanZ like family
NNMPHLEP_00139 1.1e-232 cycA E Amino acid permease
NNMPHLEP_00140 4.3e-85 perR P Belongs to the Fur family
NNMPHLEP_00141 1e-257 EGP Major facilitator Superfamily
NNMPHLEP_00142 3.2e-95 tag 3.2.2.20 L glycosylase
NNMPHLEP_00143 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NNMPHLEP_00144 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NNMPHLEP_00145 6.4e-41
NNMPHLEP_00146 3.8e-256 ytgP S Polysaccharide biosynthesis protein
NNMPHLEP_00147 7.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NNMPHLEP_00148 6.2e-276 pepV 3.5.1.18 E dipeptidase PepV
NNMPHLEP_00149 9.5e-86 uspA T Belongs to the universal stress protein A family
NNMPHLEP_00150 6.6e-174 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNMPHLEP_00151 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
NNMPHLEP_00152 2.2e-113
NNMPHLEP_00153 8.2e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
NNMPHLEP_00154 3.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NNMPHLEP_00155 2.1e-32
NNMPHLEP_00156 8.3e-117 S CAAX protease self-immunity
NNMPHLEP_00157 1.9e-43
NNMPHLEP_00159 3.8e-69
NNMPHLEP_00160 5.3e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NNMPHLEP_00161 7e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NNMPHLEP_00162 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NNMPHLEP_00163 1.8e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NNMPHLEP_00164 2.9e-102 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NNMPHLEP_00165 4.3e-206 folP 2.5.1.15 H dihydropteroate synthase
NNMPHLEP_00166 1.5e-42
NNMPHLEP_00167 1.5e-32
NNMPHLEP_00169 1.1e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NNMPHLEP_00170 1.5e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NNMPHLEP_00171 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NNMPHLEP_00172 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NNMPHLEP_00173 3.6e-37 yheA S Belongs to the UPF0342 family
NNMPHLEP_00174 1e-210 yhaO L Ser Thr phosphatase family protein
NNMPHLEP_00175 0.0 L AAA domain
NNMPHLEP_00176 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NNMPHLEP_00178 3.2e-77 hit FG histidine triad
NNMPHLEP_00179 1.3e-136 ecsA V ABC transporter, ATP-binding protein
NNMPHLEP_00180 6.2e-216 ecsB U ABC transporter
NNMPHLEP_00181 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NNMPHLEP_00182 2.3e-116 yfbR S HD containing hydrolase-like enzyme
NNMPHLEP_00183 6.9e-14
NNMPHLEP_00184 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NNMPHLEP_00185 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NNMPHLEP_00186 1.1e-245 steT E amino acid
NNMPHLEP_00187 2.7e-160 rapZ S Displays ATPase and GTPase activities
NNMPHLEP_00188 3.6e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NNMPHLEP_00189 3.1e-170 whiA K May be required for sporulation
NNMPHLEP_00191 8.8e-15
NNMPHLEP_00192 4.4e-242 glpT G Major Facilitator Superfamily
NNMPHLEP_00193 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NNMPHLEP_00195 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NNMPHLEP_00196 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NNMPHLEP_00197 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NNMPHLEP_00198 3.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NNMPHLEP_00199 1.6e-247 yifK E Amino acid permease
NNMPHLEP_00200 2.6e-291 clcA P chloride
NNMPHLEP_00201 1.8e-34 secG U Preprotein translocase
NNMPHLEP_00202 1.3e-145 est 3.1.1.1 S Serine aminopeptidase, S33
NNMPHLEP_00203 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NNMPHLEP_00204 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NNMPHLEP_00205 6.3e-105 yxjI
NNMPHLEP_00206 6.9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NNMPHLEP_00207 4.9e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NNMPHLEP_00208 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NNMPHLEP_00209 3e-87 K Acetyltransferase (GNAT) domain
NNMPHLEP_00210 2.9e-75 S PAS domain
NNMPHLEP_00211 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
NNMPHLEP_00212 7.3e-169 murB 1.3.1.98 M Cell wall formation
NNMPHLEP_00213 8.5e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NNMPHLEP_00214 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NNMPHLEP_00215 3.7e-249 fucP G Major Facilitator Superfamily
NNMPHLEP_00216 7.2e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NNMPHLEP_00217 3.3e-121 ybbR S YbbR-like protein
NNMPHLEP_00218 1.2e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NNMPHLEP_00219 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NNMPHLEP_00220 1.9e-52
NNMPHLEP_00221 0.0 oatA I Acyltransferase
NNMPHLEP_00222 3.5e-79 K Transcriptional regulator
NNMPHLEP_00223 1.5e-144 XK27_02985 S Cof-like hydrolase
NNMPHLEP_00224 6.3e-76 lytE M Lysin motif
NNMPHLEP_00231 1e-14 K Cro/C1-type HTH DNA-binding domain
NNMPHLEP_00232 2.7e-38
NNMPHLEP_00235 3.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NNMPHLEP_00236 5.7e-29
NNMPHLEP_00237 1.2e-125 mltD CBM50 M NlpC P60 family protein
NNMPHLEP_00239 7.7e-58
NNMPHLEP_00240 2.1e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NNMPHLEP_00241 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NNMPHLEP_00242 4.2e-217 patA 2.6.1.1 E Aminotransferase
NNMPHLEP_00243 5.6e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NNMPHLEP_00244 2.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NNMPHLEP_00245 4.7e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NNMPHLEP_00246 7.5e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NNMPHLEP_00247 1.9e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NNMPHLEP_00248 1.6e-260 lysC 2.7.2.4 E Belongs to the aspartokinase family
NNMPHLEP_00249 4.1e-173 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NNMPHLEP_00250 0.0 UW LPXTG-motif cell wall anchor domain protein
NNMPHLEP_00251 3.1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNMPHLEP_00252 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NNMPHLEP_00253 9e-119 S Repeat protein
NNMPHLEP_00254 4.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NNMPHLEP_00255 5.3e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NNMPHLEP_00256 2.8e-57 XK27_04120 S Putative amino acid metabolism
NNMPHLEP_00257 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
NNMPHLEP_00258 2.2e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NNMPHLEP_00260 2.4e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NNMPHLEP_00261 4.2e-32 cspA K Cold shock protein
NNMPHLEP_00262 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NNMPHLEP_00263 2.5e-42 divIVA D DivIVA domain protein
NNMPHLEP_00264 1.7e-145 ylmH S S4 domain protein
NNMPHLEP_00265 1.4e-40 yggT S YGGT family
NNMPHLEP_00266 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NNMPHLEP_00267 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NNMPHLEP_00268 1.1e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NNMPHLEP_00269 1.8e-140 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NNMPHLEP_00270 7.3e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NNMPHLEP_00271 1.1e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NNMPHLEP_00272 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NNMPHLEP_00273 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NNMPHLEP_00274 1.5e-56 ftsL D Cell division protein FtsL
NNMPHLEP_00275 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NNMPHLEP_00276 4.1e-77 mraZ K Belongs to the MraZ family
NNMPHLEP_00277 6.6e-57
NNMPHLEP_00278 1.2e-10 S Protein of unknown function (DUF4044)
NNMPHLEP_00279 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NNMPHLEP_00280 1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NNMPHLEP_00281 2.4e-161 rrmA 2.1.1.187 H Methyltransferase
NNMPHLEP_00282 7.8e-183 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NNMPHLEP_00288 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NNMPHLEP_00289 1.1e-275 lysP E amino acid
NNMPHLEP_00290 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
NNMPHLEP_00291 1e-119 lssY 3.6.1.27 I phosphatase
NNMPHLEP_00292 1.2e-82 S Threonine/Serine exporter, ThrE
NNMPHLEP_00293 3.5e-132 thrE S Putative threonine/serine exporter
NNMPHLEP_00294 3.5e-31 cspC K Cold shock protein
NNMPHLEP_00295 4.8e-125 sirR K iron dependent repressor
NNMPHLEP_00296 9.1e-167 czcD P cation diffusion facilitator family transporter
NNMPHLEP_00297 5e-117 S membrane
NNMPHLEP_00298 7.6e-110 S VIT family
NNMPHLEP_00299 5.5e-83 usp1 T Belongs to the universal stress protein A family
NNMPHLEP_00300 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NNMPHLEP_00301 1.7e-151 glnH ET ABC transporter
NNMPHLEP_00302 2.7e-109 gluC P ABC transporter permease
NNMPHLEP_00303 6.1e-109 glnP P ABC transporter permease
NNMPHLEP_00304 6.1e-216 S CAAX protease self-immunity
NNMPHLEP_00305 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNMPHLEP_00306 1.3e-54
NNMPHLEP_00307 5.2e-75 merR K MerR HTH family regulatory protein
NNMPHLEP_00308 4.7e-269 lmrB EGP Major facilitator Superfamily
NNMPHLEP_00309 1.3e-120 S Domain of unknown function (DUF4811)
NNMPHLEP_00310 2.6e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NNMPHLEP_00312 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NNMPHLEP_00313 5.9e-91 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NNMPHLEP_00314 5e-187 I Alpha beta
NNMPHLEP_00315 5e-282 emrY EGP Major facilitator Superfamily
NNMPHLEP_00316 7.2e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
NNMPHLEP_00317 1.2e-250 yjjP S Putative threonine/serine exporter
NNMPHLEP_00318 6.3e-157 mleR K LysR family
NNMPHLEP_00319 4.2e-112 ydjP I Alpha/beta hydrolase family
NNMPHLEP_00320 1e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NNMPHLEP_00321 1e-271 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NNMPHLEP_00322 5.3e-159 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NNMPHLEP_00323 7.9e-40 citD C Covalent carrier of the coenzyme of citrate lyase
NNMPHLEP_00324 5.7e-149 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NNMPHLEP_00325 4.6e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
NNMPHLEP_00326 1.8e-125 citR K sugar-binding domain protein
NNMPHLEP_00327 1e-164 citP P Sodium:sulfate symporter transmembrane region
NNMPHLEP_00328 1.8e-130 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NNMPHLEP_00329 3.6e-268 frdC 1.3.5.4 C FAD binding domain
NNMPHLEP_00330 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NNMPHLEP_00331 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NNMPHLEP_00332 3.5e-160 mleR K LysR family
NNMPHLEP_00333 5.6e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NNMPHLEP_00334 2.5e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NNMPHLEP_00335 1.5e-291 L PFAM plasmid pRiA4b ORF-3 family protein
NNMPHLEP_00336 7.6e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
NNMPHLEP_00338 0.0 S SEC-C Motif Domain Protein
NNMPHLEP_00339 1.8e-50
NNMPHLEP_00340 6.2e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NNMPHLEP_00341 4e-54 V Abi-like protein
NNMPHLEP_00346 3.9e-156 lysA2 M Glycosyl hydrolases family 25
NNMPHLEP_00347 4.9e-45 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NNMPHLEP_00348 4.5e-17
NNMPHLEP_00349 3.5e-64 S Domain of unknown function (DUF2479)
NNMPHLEP_00352 1.6e-188 S Peptidase family M23
NNMPHLEP_00353 1e-96 S Phage tail protein
NNMPHLEP_00354 3.1e-261 D NLP P60 protein
NNMPHLEP_00355 2.4e-90 S Phage tail assembly chaperone protein, TAC
NNMPHLEP_00356 1e-119
NNMPHLEP_00357 4.6e-70
NNMPHLEP_00358 4.2e-82
NNMPHLEP_00359 3.7e-51
NNMPHLEP_00360 4.1e-62 S Phage gp6-like head-tail connector protein
NNMPHLEP_00361 6.8e-143 gpG
NNMPHLEP_00362 5.4e-97 S Domain of unknown function (DUF4355)
NNMPHLEP_00364 3.2e-175 S Phage Mu protein F like protein
NNMPHLEP_00365 7.1e-303 S Phage portal protein, SPP1 Gp6-like
NNMPHLEP_00366 1.6e-254 S Phage terminase, large subunit
NNMPHLEP_00368 2.8e-124 K Belongs to the N(4) N(6)-methyltransferase family
NNMPHLEP_00370 1e-119 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
NNMPHLEP_00371 5.8e-76
NNMPHLEP_00375 4.1e-07
NNMPHLEP_00378 1.5e-21
NNMPHLEP_00380 9.8e-14
NNMPHLEP_00381 6.1e-51 S ORF6C domain
NNMPHLEP_00383 2.3e-24
NNMPHLEP_00384 9.7e-73 L Psort location Cytoplasmic, score
NNMPHLEP_00385 5.1e-137 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NNMPHLEP_00386 1.7e-152 recT L RecT family
NNMPHLEP_00392 1.3e-09 K Helix-turn-helix XRE-family like proteins
NNMPHLEP_00393 3e-14 K sequence-specific DNA binding
NNMPHLEP_00395 7.3e-12
NNMPHLEP_00397 2.4e-92 L Belongs to the 'phage' integrase family
NNMPHLEP_00398 1.8e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NNMPHLEP_00399 1.8e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NNMPHLEP_00400 1.5e-228 clcA_2 P Chloride transporter, ClC family
NNMPHLEP_00401 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NNMPHLEP_00402 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
NNMPHLEP_00403 2.5e-124 srtA 3.4.22.70 M sortase family
NNMPHLEP_00404 2e-166 S Alpha/beta hydrolase of unknown function (DUF915)
NNMPHLEP_00405 1.8e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NNMPHLEP_00406 4.6e-41 rpmE2 J Ribosomal protein L31
NNMPHLEP_00407 1.3e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNMPHLEP_00408 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NNMPHLEP_00409 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NNMPHLEP_00410 3e-66 ywiB S Domain of unknown function (DUF1934)
NNMPHLEP_00411 6.7e-145 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
NNMPHLEP_00412 1.7e-270 ywfO S HD domain protein
NNMPHLEP_00413 8.4e-148 yxeH S hydrolase
NNMPHLEP_00414 8.1e-49
NNMPHLEP_00415 3.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NNMPHLEP_00416 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NNMPHLEP_00417 2.6e-149 purR 2.4.2.7 F pur operon repressor
NNMPHLEP_00418 4.7e-119 znuB U ABC 3 transport family
NNMPHLEP_00419 2.2e-122 fhuC P ABC transporter
NNMPHLEP_00420 2.5e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
NNMPHLEP_00421 1.2e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NNMPHLEP_00422 6.8e-37 veg S Biofilm formation stimulator VEG
NNMPHLEP_00423 1e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NNMPHLEP_00424 3.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NNMPHLEP_00425 1.1e-155 tatD L hydrolase, TatD family
NNMPHLEP_00426 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NNMPHLEP_00427 6.4e-159 yunF F Protein of unknown function DUF72
NNMPHLEP_00429 8.8e-130 cobB K SIR2 family
NNMPHLEP_00430 1e-176
NNMPHLEP_00431 1.5e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NNMPHLEP_00432 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NNMPHLEP_00433 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NNMPHLEP_00434 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NNMPHLEP_00435 8.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
NNMPHLEP_00436 0.0 helD 3.6.4.12 L DNA helicase
NNMPHLEP_00437 1.6e-200 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NNMPHLEP_00438 1.9e-197 clcA P chloride
NNMPHLEP_00439 4.5e-40 L Transposase, IS116 IS110 IS902 family
NNMPHLEP_00441 3.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NNMPHLEP_00442 4.3e-267 yfnA E amino acid
NNMPHLEP_00443 3.5e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NNMPHLEP_00444 4e-41 1.3.5.4 S FMN binding
NNMPHLEP_00445 1.3e-221 norA EGP Major facilitator Superfamily
NNMPHLEP_00446 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NNMPHLEP_00447 5.9e-152 metQ1 P Belongs to the nlpA lipoprotein family
NNMPHLEP_00448 8e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NNMPHLEP_00449 3.1e-103 metI P ABC transporter permease
NNMPHLEP_00450 6.3e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NNMPHLEP_00451 5.7e-29 clcA P chloride
NNMPHLEP_00452 5.1e-99 clcA P chloride
NNMPHLEP_00453 5.3e-150 3.1.3.102, 3.1.3.104 S hydrolase
NNMPHLEP_00454 4e-49 yrvD S Pfam:DUF1049
NNMPHLEP_00456 5.1e-140 L Belongs to the 'phage' integrase family
NNMPHLEP_00458 6.1e-24
NNMPHLEP_00461 1.8e-18
NNMPHLEP_00465 2.1e-20 E Zn peptidase
NNMPHLEP_00466 7.7e-29 2.6.1.2, 2.6.1.66 K Helix-turn-helix XRE-family like proteins
NNMPHLEP_00467 4e-23 K Protein of unknown function (DUF739)
NNMPHLEP_00472 1.3e-19
NNMPHLEP_00475 5.9e-102 L DnaD domain protein
NNMPHLEP_00477 8.2e-62
NNMPHLEP_00478 1.8e-112
NNMPHLEP_00480 2.9e-21 S ORF6C domain
NNMPHLEP_00481 1.4e-15
NNMPHLEP_00485 2.2e-54
NNMPHLEP_00489 1.2e-08
NNMPHLEP_00490 9.5e-89 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NNMPHLEP_00491 6.5e-171 bcgIA 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NNMPHLEP_00492 1.4e-66 L HNH nucleases
NNMPHLEP_00493 1.7e-65 L Phage terminase, small subunit
NNMPHLEP_00494 7e-291 S overlaps another CDS with the same product name
NNMPHLEP_00496 6.6e-210 S Phage portal protein
NNMPHLEP_00497 2.8e-107 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NNMPHLEP_00498 7.7e-179 S Phage capsid family
NNMPHLEP_00499 2.1e-39 S Phage gp6-like head-tail connector protein
NNMPHLEP_00500 6.4e-10 S head-tail joining protein
NNMPHLEP_00501 1.1e-37 S exonuclease activity
NNMPHLEP_00502 4.4e-19 S Protein of unknown function (DUF806)
NNMPHLEP_00503 9.2e-78 S Phage tail tube protein
NNMPHLEP_00504 9.1e-14 S Phage tail assembly chaperone proteins, TAC
NNMPHLEP_00506 8.9e-178 M Phage tail tape measure protein TP901
NNMPHLEP_00507 2.2e-85 S Phage tail protein
NNMPHLEP_00508 2e-142 ydhO 3.4.14.13 M Prophage endopeptidase tail
NNMPHLEP_00509 9.1e-91 GT2,GT4 LM gp58-like protein
NNMPHLEP_00516 9.4e-29 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NNMPHLEP_00517 2.1e-149 lysA2 M Glycosyl hydrolases family 25
NNMPHLEP_00518 6.3e-123 L Helix-turn-helix domain
NNMPHLEP_00519 4.8e-114 frnE Q DSBA-like thioredoxin domain
NNMPHLEP_00520 1.4e-54
NNMPHLEP_00521 8.4e-30 L PFAM transposase IS200-family protein
NNMPHLEP_00522 2.7e-32
NNMPHLEP_00523 0.0 clpL O associated with various cellular activities
NNMPHLEP_00524 2.1e-165 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NNMPHLEP_00526 1.7e-105 wecD3 K PFAM GCN5-related N-acetyltransferase
NNMPHLEP_00527 2.5e-83 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNMPHLEP_00528 8.3e-190 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNMPHLEP_00529 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NNMPHLEP_00530 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NNMPHLEP_00531 4.3e-172 malR K Transcriptional regulator, LacI family
NNMPHLEP_00532 1.2e-211 phbA 2.3.1.9 I Belongs to the thiolase family
NNMPHLEP_00533 1.1e-256 malT G Major Facilitator
NNMPHLEP_00534 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NNMPHLEP_00535 2.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NNMPHLEP_00536 5.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NNMPHLEP_00537 7.8e-137 puuD S peptidase C26
NNMPHLEP_00538 5.9e-168 yvgN C Aldo keto reductase
NNMPHLEP_00539 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
NNMPHLEP_00540 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NNMPHLEP_00541 2.3e-87 hmpT S ECF-type riboflavin transporter, S component
NNMPHLEP_00542 1.1e-261 nox C NADH oxidase
NNMPHLEP_00543 3.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNMPHLEP_00544 1.5e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NNMPHLEP_00545 2.7e-87
NNMPHLEP_00546 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NNMPHLEP_00548 6.6e-136 puuD S peptidase C26
NNMPHLEP_00549 9.3e-248 steT_1 E amino acid
NNMPHLEP_00550 3.3e-107 K Transcriptional regulator, TetR family
NNMPHLEP_00551 1e-74 V ATPases associated with a variety of cellular activities
NNMPHLEP_00552 1.1e-31 S ABC-type transport system involved in multi-copper enzyme maturation permease component
NNMPHLEP_00553 2.9e-69
NNMPHLEP_00554 5.6e-262 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NNMPHLEP_00555 1.6e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NNMPHLEP_00556 3.2e-280 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
NNMPHLEP_00557 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NNMPHLEP_00558 8.9e-267 G Major Facilitator
NNMPHLEP_00559 1e-259 G Major Facilitator
NNMPHLEP_00560 3.4e-183 K Transcriptional regulator, LacI family
NNMPHLEP_00561 5.9e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNMPHLEP_00563 2.4e-101 nqr 1.5.1.36 S reductase
NNMPHLEP_00564 1.4e-194 XK27_09615 S reductase
NNMPHLEP_00565 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NNMPHLEP_00566 2.3e-102 fhaB M Rib/alpha-like repeat
NNMPHLEP_00568 4.2e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NNMPHLEP_00569 1.8e-265 glnP P ABC transporter
NNMPHLEP_00570 1.9e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NNMPHLEP_00571 2.5e-221 cycA E Amino acid permease
NNMPHLEP_00572 1.1e-217 nupG F Nucleoside transporter
NNMPHLEP_00573 1.7e-170 rihC 3.2.2.1 F Nucleoside
NNMPHLEP_00574 4.2e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NNMPHLEP_00575 1e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NNMPHLEP_00576 4.3e-151 noc K Belongs to the ParB family
NNMPHLEP_00577 3.9e-139 soj D Sporulation initiation inhibitor
NNMPHLEP_00578 6.5e-154 spo0J K Belongs to the ParB family
NNMPHLEP_00579 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
NNMPHLEP_00580 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NNMPHLEP_00581 7.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
NNMPHLEP_00582 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NNMPHLEP_00583 3.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NNMPHLEP_00584 4.8e-238 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
NNMPHLEP_00585 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NNMPHLEP_00586 4.7e-171 deoR K sugar-binding domain protein
NNMPHLEP_00587 5.9e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NNMPHLEP_00588 3.8e-125 K response regulator
NNMPHLEP_00589 5.9e-200 hpk31 2.7.13.3 T Histidine kinase
NNMPHLEP_00590 8.5e-141 azlC E AzlC protein
NNMPHLEP_00591 5.6e-53 azlD S branched-chain amino acid
NNMPHLEP_00592 8.7e-135 K LysR substrate binding domain
NNMPHLEP_00593 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NNMPHLEP_00594 4.4e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NNMPHLEP_00595 5.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NNMPHLEP_00596 8.6e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NNMPHLEP_00597 1.9e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NNMPHLEP_00598 5.3e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
NNMPHLEP_00599 9e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NNMPHLEP_00600 6.4e-177 K AI-2E family transporter
NNMPHLEP_00601 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NNMPHLEP_00602 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NNMPHLEP_00603 6.7e-125 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NNMPHLEP_00604 2.2e-186 thrC 4.2.3.1 E Threonine synthase
NNMPHLEP_00605 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NNMPHLEP_00606 2.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NNMPHLEP_00607 3.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NNMPHLEP_00608 2.4e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NNMPHLEP_00609 1.2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NNMPHLEP_00610 4.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NNMPHLEP_00611 1.9e-34 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNMPHLEP_00612 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNMPHLEP_00613 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NNMPHLEP_00614 1e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NNMPHLEP_00615 1.1e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NNMPHLEP_00616 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NNMPHLEP_00617 4.7e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NNMPHLEP_00618 3.1e-242 purD 6.3.4.13 F Belongs to the GARS family
NNMPHLEP_00619 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NNMPHLEP_00620 1.6e-167
NNMPHLEP_00621 2.9e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NNMPHLEP_00622 1.2e-135 IQ KR domain
NNMPHLEP_00623 1e-181 iunH2 3.2.2.1 F nucleoside hydrolase
NNMPHLEP_00624 2.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NNMPHLEP_00625 4.4e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NNMPHLEP_00626 5.1e-249 yagE E amino acid
NNMPHLEP_00627 2.2e-84 dps P Belongs to the Dps family
NNMPHLEP_00628 0.0 pacL 3.6.3.8 P P-type ATPase
NNMPHLEP_00629 2.5e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NNMPHLEP_00630 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NNMPHLEP_00631 5.9e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NNMPHLEP_00632 4.5e-146 potB P ABC transporter permease
NNMPHLEP_00633 1.9e-139 potC P ABC transporter permease
NNMPHLEP_00634 3.3e-208 potD P ABC transporter
NNMPHLEP_00635 4.3e-231
NNMPHLEP_00636 5e-235 EGP Sugar (and other) transporter
NNMPHLEP_00637 1e-254 yfnA E Amino Acid
NNMPHLEP_00638 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NNMPHLEP_00639 6.4e-102 gmk2 2.7.4.8 F Guanylate kinase
NNMPHLEP_00640 1.5e-82 zur P Belongs to the Fur family
NNMPHLEP_00641 1.2e-16 3.2.1.14 GH18
NNMPHLEP_00642 5.4e-150
NNMPHLEP_00643 3.7e-38 pspC KT PspC domain protein
NNMPHLEP_00644 1.6e-94 K Transcriptional regulator (TetR family)
NNMPHLEP_00645 3.1e-221 V domain protein
NNMPHLEP_00646 1.2e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNMPHLEP_00648 6.6e-35 S Transglycosylase associated protein
NNMPHLEP_00649 3.2e-234 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NNMPHLEP_00650 1.9e-126 G phosphoglycerate mutase
NNMPHLEP_00651 8.8e-116 dedA S SNARE associated Golgi protein
NNMPHLEP_00652 0.0 helD 3.6.4.12 L DNA helicase
NNMPHLEP_00653 1.6e-244 nox C NADH oxidase
NNMPHLEP_00654 1.1e-253 nox C NADH oxidase
NNMPHLEP_00655 5.1e-159 EG EamA-like transporter family
NNMPHLEP_00656 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NNMPHLEP_00657 8.2e-176 coaA 2.7.1.33 F Pantothenic acid kinase
NNMPHLEP_00658 4.3e-225 S cog cog1373
NNMPHLEP_00660 6.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NNMPHLEP_00661 4.7e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NNMPHLEP_00664 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NNMPHLEP_00665 1.2e-42 K HxlR-like helix-turn-helix
NNMPHLEP_00666 1.1e-59 S macrophage migration inhibitory factor
NNMPHLEP_00667 2.2e-168 yqiG C Oxidoreductase
NNMPHLEP_00669 2.4e-18
NNMPHLEP_00670 1.3e-263 dtpT U amino acid peptide transporter
NNMPHLEP_00671 2e-149 yjjH S Calcineurin-like phosphoesterase
NNMPHLEP_00674 6.5e-111
NNMPHLEP_00675 5e-249 EGP Major facilitator Superfamily
NNMPHLEP_00676 6e-302 aspT P Predicted Permease Membrane Region
NNMPHLEP_00677 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NNMPHLEP_00678 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
NNMPHLEP_00679 4.5e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NNMPHLEP_00680 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NNMPHLEP_00681 0.0 yhgF K Tex-like protein N-terminal domain protein
NNMPHLEP_00682 3.3e-85 ydcK S Belongs to the SprT family
NNMPHLEP_00684 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NNMPHLEP_00685 1.9e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NNMPHLEP_00686 0.0 S Bacterial membrane protein, YfhO
NNMPHLEP_00687 3.5e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NNMPHLEP_00688 1.1e-169 I alpha/beta hydrolase fold
NNMPHLEP_00689 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NNMPHLEP_00690 1.1e-119 tcyB E ABC transporter
NNMPHLEP_00691 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NNMPHLEP_00692 2.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NNMPHLEP_00693 2.8e-265 pepC 3.4.22.40 E Peptidase C1-like family
NNMPHLEP_00694 7.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NNMPHLEP_00695 7.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
NNMPHLEP_00696 3.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NNMPHLEP_00697 3.9e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NNMPHLEP_00698 8.6e-207 yacL S domain protein
NNMPHLEP_00699 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NNMPHLEP_00700 9.4e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NNMPHLEP_00701 2.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNMPHLEP_00702 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NNMPHLEP_00703 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NNMPHLEP_00704 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
NNMPHLEP_00705 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NNMPHLEP_00706 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NNMPHLEP_00707 5.4e-228 aadAT EK Aminotransferase, class I
NNMPHLEP_00709 1.3e-235 M Glycosyl transferase family group 2
NNMPHLEP_00710 4.2e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NNMPHLEP_00711 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NNMPHLEP_00712 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NNMPHLEP_00713 5.9e-48
NNMPHLEP_00715 1.1e-231 S Putative metallopeptidase domain
NNMPHLEP_00716 2.4e-201 3.1.3.1 S associated with various cellular activities
NNMPHLEP_00717 2.6e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NNMPHLEP_00718 1.5e-64 yeaO S Protein of unknown function, DUF488
NNMPHLEP_00720 4.6e-115 yrkL S Flavodoxin-like fold
NNMPHLEP_00721 3.6e-54
NNMPHLEP_00722 1.3e-19 S Domain of unknown function (DUF4767)
NNMPHLEP_00723 4.4e-123 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NNMPHLEP_00724 3.1e-49
NNMPHLEP_00725 5.1e-201 nrnB S DHHA1 domain
NNMPHLEP_00726 3.9e-229 S Uncharacterized protein conserved in bacteria (DUF2325)
NNMPHLEP_00727 5.1e-246 brnQ U Component of the transport system for branched-chain amino acids
NNMPHLEP_00728 9.9e-106 NU mannosyl-glycoprotein
NNMPHLEP_00729 2.6e-138 S Putative ABC-transporter type IV
NNMPHLEP_00730 1e-271 S ABC transporter, ATP-binding protein
NNMPHLEP_00731 2.2e-84 K Helix-turn-helix domain
NNMPHLEP_00732 1.7e-48
NNMPHLEP_00734 1.7e-33 F Belongs to the NrdI family
NNMPHLEP_00735 2.6e-41 3.4.22.70 M Sortase family
NNMPHLEP_00736 6.9e-73 K Transcriptional regulator, TetR family
NNMPHLEP_00737 7e-75 M PFAM NLP P60 protein
NNMPHLEP_00738 1.3e-182 ABC-SBP S ABC transporter
NNMPHLEP_00739 1.9e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NNMPHLEP_00740 8.2e-137 XK27_08845 S ABC transporter, ATP-binding protein
NNMPHLEP_00741 2e-92 P Cadmium resistance transporter
NNMPHLEP_00742 3.8e-54 K Transcriptional regulator, ArsR family
NNMPHLEP_00743 6.8e-53 trxA O Belongs to the thioredoxin family
NNMPHLEP_00744 6.6e-131 terC P membrane
NNMPHLEP_00745 3.6e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NNMPHLEP_00746 9.7e-169 corA P CorA-like Mg2+ transporter protein
NNMPHLEP_00747 1e-281 pipD E Dipeptidase
NNMPHLEP_00748 2.8e-241 pbuX F xanthine permease
NNMPHLEP_00749 8.5e-249 nhaC C Na H antiporter NhaC
NNMPHLEP_00750 1.8e-279 S C4-dicarboxylate anaerobic carrier
NNMPHLEP_00751 2.3e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
NNMPHLEP_00752 2.1e-39
NNMPHLEP_00753 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NNMPHLEP_00754 4.4e-208 gldA 1.1.1.6 C dehydrogenase
NNMPHLEP_00755 0.0 M domain protein
NNMPHLEP_00756 4.6e-34
NNMPHLEP_00757 9.4e-189 ampC V Beta-lactamase
NNMPHLEP_00758 2e-238 arcA 3.5.3.6 E Arginine
NNMPHLEP_00759 8e-79 argR K Regulates arginine biosynthesis genes
NNMPHLEP_00760 7.5e-261 E Arginine ornithine antiporter
NNMPHLEP_00761 3.6e-223 arcD U Amino acid permease
NNMPHLEP_00763 4.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NNMPHLEP_00764 2.9e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
NNMPHLEP_00765 6e-108 tdk 2.7.1.21 F thymidine kinase
NNMPHLEP_00766 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NNMPHLEP_00767 3e-164 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NNMPHLEP_00768 2.7e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NNMPHLEP_00769 1.2e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NNMPHLEP_00770 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NNMPHLEP_00771 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NNMPHLEP_00772 1.2e-189 yibE S overlaps another CDS with the same product name
NNMPHLEP_00773 1.4e-128 yibF S overlaps another CDS with the same product name
NNMPHLEP_00774 2.1e-230 pyrP F Permease
NNMPHLEP_00775 6.9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
NNMPHLEP_00776 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNMPHLEP_00777 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NNMPHLEP_00778 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NNMPHLEP_00779 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NNMPHLEP_00780 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NNMPHLEP_00781 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NNMPHLEP_00782 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NNMPHLEP_00783 2.2e-33 ywzB S Protein of unknown function (DUF1146)
NNMPHLEP_00784 9.4e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NNMPHLEP_00785 1.9e-178 mbl D Cell shape determining protein MreB Mrl
NNMPHLEP_00786 1e-31 S Protein of unknown function (DUF2969)
NNMPHLEP_00787 1.4e-220 rodA D Belongs to the SEDS family
NNMPHLEP_00788 1.4e-47 gcvH E glycine cleavage
NNMPHLEP_00789 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NNMPHLEP_00790 9.6e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NNMPHLEP_00791 8.9e-92 L PFAM Integrase catalytic region
NNMPHLEP_00792 6.6e-21
NNMPHLEP_00793 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NNMPHLEP_00795 1.4e-34 yxiO S Vacuole effluxer Atg22 like
NNMPHLEP_00796 2.7e-22 yxiO S Vacuole effluxer Atg22 like
NNMPHLEP_00797 1.2e-103 yxiO S Vacuole effluxer Atg22 like
NNMPHLEP_00798 3.3e-247 npp S type I phosphodiesterase nucleotide pyrophosphatase
NNMPHLEP_00799 1.2e-239 E amino acid
NNMPHLEP_00800 6.7e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNMPHLEP_00801 5.1e-220 yxjG_1 E methionine synthase, vitamin-B12 independent
NNMPHLEP_00802 1.7e-40 S Cytochrome B5
NNMPHLEP_00803 5.4e-09 S Cytochrome B5
NNMPHLEP_00804 7e-39 S Cytochrome B5
NNMPHLEP_00805 6.4e-38 elaA S Gnat family
NNMPHLEP_00806 1.3e-07 elaA S Gnat family
NNMPHLEP_00807 3e-10 GM NmrA-like family
NNMPHLEP_00808 2.8e-51 hxlR K Transcriptional regulator, HxlR family
NNMPHLEP_00809 5.3e-107 XK27_02070 S Nitroreductase family
NNMPHLEP_00810 8.7e-78 K Transcriptional regulator, HxlR family
NNMPHLEP_00811 1e-227
NNMPHLEP_00812 1e-210 EGP Major facilitator Superfamily
NNMPHLEP_00813 1.8e-253 pepC 3.4.22.40 E aminopeptidase
NNMPHLEP_00814 5.5e-110 ylbE GM NAD dependent epimerase dehydratase family protein
NNMPHLEP_00815 0.0 pepN 3.4.11.2 E aminopeptidase
NNMPHLEP_00816 1.6e-89 folT S ECF transporter, substrate-specific component
NNMPHLEP_00817 9.3e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
NNMPHLEP_00818 2.7e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NNMPHLEP_00819 8.5e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
NNMPHLEP_00820 4.1e-62 yneR
NNMPHLEP_00821 5.6e-158 akr5f 1.1.1.346 S reductase
NNMPHLEP_00822 1.3e-154 K Transcriptional regulator
NNMPHLEP_00823 5.7e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
NNMPHLEP_00824 6.2e-153 ypuA S Protein of unknown function (DUF1002)
NNMPHLEP_00825 1.2e-227 aadAT EK Aminotransferase, class I
NNMPHLEP_00826 8.5e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NNMPHLEP_00827 1.9e-152 tesE Q hydratase
NNMPHLEP_00828 3.7e-146 S Alpha beta hydrolase
NNMPHLEP_00829 2.2e-64 lacA S transferase hexapeptide repeat
NNMPHLEP_00830 0.0 uup S ABC transporter, ATP-binding protein
NNMPHLEP_00831 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NNMPHLEP_00832 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NNMPHLEP_00833 9.4e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NNMPHLEP_00834 2e-80 S YbaK proline--tRNA ligase associated domain protein
NNMPHLEP_00835 8.1e-304 ybeC E amino acid
NNMPHLEP_00836 0.0 ydaO E amino acid
NNMPHLEP_00837 3e-38
NNMPHLEP_00838 2.6e-65 rmaI K Transcriptional regulator
NNMPHLEP_00839 5.6e-24 yaaU EGP Major facilitator Superfamily
NNMPHLEP_00840 8.1e-86 yaaU EGP Major facilitator Superfamily
NNMPHLEP_00841 5.1e-76 EGP Major facilitator Superfamily
NNMPHLEP_00842 3.7e-111 yvyE 3.4.13.9 S YigZ family
NNMPHLEP_00843 1.3e-254 comFA L Helicase C-terminal domain protein
NNMPHLEP_00844 7.5e-126 comFC S Competence protein
NNMPHLEP_00845 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NNMPHLEP_00846 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNMPHLEP_00847 3.9e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NNMPHLEP_00848 5.3e-32 KT PspC domain protein
NNMPHLEP_00849 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NNMPHLEP_00850 6.6e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NNMPHLEP_00851 1.2e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NNMPHLEP_00852 2.2e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NNMPHLEP_00853 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NNMPHLEP_00854 6.6e-136 yrjD S LUD domain
NNMPHLEP_00855 1.3e-287 lutB C 4Fe-4S dicluster domain
NNMPHLEP_00856 1.7e-156 lutA C Cysteine-rich domain
NNMPHLEP_00857 3.9e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NNMPHLEP_00858 2.4e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NNMPHLEP_00859 8.2e-165 aatB ET PFAM extracellular solute-binding protein, family 3
NNMPHLEP_00860 1.2e-88 ykhA 3.1.2.20 I Thioesterase superfamily
NNMPHLEP_00861 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NNMPHLEP_00862 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NNMPHLEP_00863 4.8e-229 mtnE 2.6.1.83 E Aminotransferase
NNMPHLEP_00864 2.4e-144 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NNMPHLEP_00865 6.7e-35 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNMPHLEP_00866 6.6e-81 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NNMPHLEP_00867 5.3e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NNMPHLEP_00868 4.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NNMPHLEP_00869 8e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NNMPHLEP_00870 1.6e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NNMPHLEP_00871 2.7e-129 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NNMPHLEP_00872 1.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NNMPHLEP_00873 3.3e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NNMPHLEP_00874 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NNMPHLEP_00875 2.6e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NNMPHLEP_00876 3.6e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
NNMPHLEP_00877 6.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NNMPHLEP_00878 5.9e-58 yabA L Involved in initiation control of chromosome replication
NNMPHLEP_00879 1e-182 holB 2.7.7.7 L DNA polymerase III
NNMPHLEP_00880 7.6e-52 yaaQ S Cyclic-di-AMP receptor
NNMPHLEP_00881 4.3e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NNMPHLEP_00882 9.7e-39 S Protein of unknown function (DUF2508)
NNMPHLEP_00883 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NNMPHLEP_00884 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NNMPHLEP_00885 6e-279 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNMPHLEP_00886 1e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NNMPHLEP_00887 3.4e-35 nrdH O Glutaredoxin
NNMPHLEP_00888 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNMPHLEP_00889 1.3e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NNMPHLEP_00890 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NNMPHLEP_00891 5.2e-136 S Putative adhesin
NNMPHLEP_00892 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
NNMPHLEP_00893 1.1e-56 K transcriptional regulator PadR family
NNMPHLEP_00894 2e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NNMPHLEP_00895 1.1e-33
NNMPHLEP_00896 8.4e-54 S Mazg nucleotide pyrophosphohydrolase
NNMPHLEP_00897 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
NNMPHLEP_00898 6.6e-84
NNMPHLEP_00899 1.4e-187 lacR K Transcriptional regulator
NNMPHLEP_00900 0.0 lacS G Transporter
NNMPHLEP_00901 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NNMPHLEP_00902 4.3e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NNMPHLEP_00903 6.8e-159 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NNMPHLEP_00904 8.4e-113 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
NNMPHLEP_00905 6.5e-23 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
NNMPHLEP_00906 1.6e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
NNMPHLEP_00907 1.2e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NNMPHLEP_00908 2.4e-223 mdtG EGP Major facilitator Superfamily
NNMPHLEP_00909 5.5e-149 T Calcineurin-like phosphoesterase superfamily domain
NNMPHLEP_00910 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NNMPHLEP_00912 1e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NNMPHLEP_00913 3.8e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NNMPHLEP_00914 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
NNMPHLEP_00915 0.0 trxB2 1.8.1.9 C Thioredoxin domain
NNMPHLEP_00916 0.0 M LPXTG-motif cell wall anchor domain protein
NNMPHLEP_00917 2e-41 cpsJ S glycosyl transferase family 2
NNMPHLEP_00918 4.2e-49 cpsJ S glycosyl transferase family 2
NNMPHLEP_00919 9.2e-50 M family 8
NNMPHLEP_00920 3.6e-245 M family 8
NNMPHLEP_00925 2.4e-149 2.1.1.72 V type I restriction-modification system
NNMPHLEP_00926 5.5e-37 S Type I restriction modification DNA specificity domain
NNMPHLEP_00927 4.3e-118 xtmA L Terminase small subunit
NNMPHLEP_00928 4.9e-219 S Terminase-like family
NNMPHLEP_00929 2.7e-216 S Phage portal protein, SPP1 Gp6-like
NNMPHLEP_00930 1.3e-148 S Phage Mu protein F like protein
NNMPHLEP_00931 3.4e-51 S Domain of unknown function (DUF4355)
NNMPHLEP_00932 3.6e-53
NNMPHLEP_00933 2.7e-167 S Phage major capsid protein E
NNMPHLEP_00934 7.3e-36
NNMPHLEP_00935 1e-57
NNMPHLEP_00936 1.8e-77
NNMPHLEP_00937 4.7e-45
NNMPHLEP_00938 6.5e-71 S Phage tail tube protein, TTP
NNMPHLEP_00939 6.9e-58
NNMPHLEP_00940 5.7e-32
NNMPHLEP_00941 0.0 M Phage tail tape measure protein TP901
NNMPHLEP_00942 8.4e-52
NNMPHLEP_00943 0.0 GT2,GT4 LM gp58-like protein
NNMPHLEP_00945 4.8e-12
NNMPHLEP_00946 2.6e-15 S Bacteriophage holin family
NNMPHLEP_00947 7.2e-183 M lysozyme activity
NNMPHLEP_00951 1.1e-102 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NNMPHLEP_00952 2.4e-14 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NNMPHLEP_00953 6.6e-134 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NNMPHLEP_00954 1.3e-79 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NNMPHLEP_00955 1.1e-107 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NNMPHLEP_00956 1.7e-116 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NNMPHLEP_00957 9.6e-119 IQ reductase
NNMPHLEP_00958 3e-149 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NNMPHLEP_00959 1.8e-13 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNMPHLEP_00960 3.7e-09 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNMPHLEP_00961 3e-51 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNMPHLEP_00962 3.9e-70 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NNMPHLEP_00963 1.4e-75 marR K Transcriptional regulator, MarR family
NNMPHLEP_00964 1.6e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NNMPHLEP_00966 6.2e-199 xerS L Belongs to the 'phage' integrase family
NNMPHLEP_00967 9.1e-83 L PFAM transposase IS200-family protein
NNMPHLEP_00968 3.1e-25 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NNMPHLEP_00969 5.5e-158 rssA S Phospholipase, patatin family
NNMPHLEP_00970 3.2e-118 L Integrase
NNMPHLEP_00971 6.8e-151 EG EamA-like transporter family
NNMPHLEP_00972 2.5e-129 narI 1.7.5.1 C Nitrate reductase
NNMPHLEP_00973 5.6e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
NNMPHLEP_00974 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
NNMPHLEP_00975 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NNMPHLEP_00976 1.4e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
NNMPHLEP_00977 1.7e-79 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NNMPHLEP_00978 2.7e-227 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
NNMPHLEP_00979 3.3e-83 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NNMPHLEP_00980 1.1e-104 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NNMPHLEP_00981 3e-44
NNMPHLEP_00982 5.1e-90 comP 2.7.13.3 F Sensor histidine kinase
NNMPHLEP_00983 1.7e-37
NNMPHLEP_00986 1.4e-61 rusA L Endodeoxyribonuclease RusA
NNMPHLEP_00987 5.6e-23
NNMPHLEP_00992 3.5e-77 Q DNA (cytosine-5-)-methyltransferase activity
NNMPHLEP_00996 2.3e-16
NNMPHLEP_00998 5.8e-49 S ORF6C domain
NNMPHLEP_01001 2.7e-28
NNMPHLEP_01002 3.9e-47 S Conserved phage C-terminus (Phg_2220_C)
NNMPHLEP_01003 1.2e-73 S Putative HNHc nuclease
NNMPHLEP_01004 1.7e-36 S Protein of unknown function (DUF669)
NNMPHLEP_01005 1.4e-82 S AAA domain
NNMPHLEP_01006 6.1e-83 S Bacteriophage Mu Gam like protein
NNMPHLEP_01011 2.2e-28
NNMPHLEP_01014 2.1e-18
NNMPHLEP_01016 9.4e-12
NNMPHLEP_01017 8.4e-54 K Cro/C1-type HTH DNA-binding domain
NNMPHLEP_01018 2.8e-81 E IrrE N-terminal-like domain
NNMPHLEP_01019 3.1e-19
NNMPHLEP_01020 8.7e-41
NNMPHLEP_01022 1e-45
NNMPHLEP_01023 3.7e-170 L Belongs to the 'phage' integrase family
NNMPHLEP_01024 2.5e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NNMPHLEP_01025 4.4e-261 yfnA E amino acid
NNMPHLEP_01026 1.3e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NNMPHLEP_01027 5e-90 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NNMPHLEP_01028 2.7e-39 ylqC S Belongs to the UPF0109 family
NNMPHLEP_01029 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NNMPHLEP_01030 3.9e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NNMPHLEP_01031 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NNMPHLEP_01032 1.4e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NNMPHLEP_01033 0.0 smc D Required for chromosome condensation and partitioning
NNMPHLEP_01034 1.8e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NNMPHLEP_01035 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NNMPHLEP_01036 3.7e-185 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NNMPHLEP_01037 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NNMPHLEP_01038 0.0 yloV S DAK2 domain fusion protein YloV
NNMPHLEP_01039 4.7e-58 asp S Asp23 family, cell envelope-related function
NNMPHLEP_01040 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NNMPHLEP_01041 4.8e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
NNMPHLEP_01042 3.6e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NNMPHLEP_01043 2.7e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NNMPHLEP_01044 0.0 KLT serine threonine protein kinase
NNMPHLEP_01045 8.5e-131 stp 3.1.3.16 T phosphatase
NNMPHLEP_01046 1.8e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NNMPHLEP_01047 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NNMPHLEP_01048 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NNMPHLEP_01049 1.2e-211 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NNMPHLEP_01050 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NNMPHLEP_01051 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NNMPHLEP_01052 1.4e-53
NNMPHLEP_01053 6.1e-262 recN L May be involved in recombinational repair of damaged DNA
NNMPHLEP_01054 2.5e-77 argR K Regulates arginine biosynthesis genes
NNMPHLEP_01055 5.3e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NNMPHLEP_01056 4.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NNMPHLEP_01057 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNMPHLEP_01058 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NNMPHLEP_01059 2.1e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NNMPHLEP_01060 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NNMPHLEP_01061 8.4e-70 yqhY S Asp23 family, cell envelope-related function
NNMPHLEP_01062 2e-110 J 2'-5' RNA ligase superfamily
NNMPHLEP_01063 1.4e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NNMPHLEP_01064 7.1e-127 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NNMPHLEP_01065 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NNMPHLEP_01066 3.7e-54 ysxB J Cysteine protease Prp
NNMPHLEP_01067 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NNMPHLEP_01068 5.8e-112 K Transcriptional regulator
NNMPHLEP_01071 1.1e-86 dut S Protein conserved in bacteria
NNMPHLEP_01072 3.6e-172
NNMPHLEP_01073 5.2e-151
NNMPHLEP_01074 8.2e-51 S Iron-sulfur cluster assembly protein
NNMPHLEP_01075 3.6e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NNMPHLEP_01076 1.4e-153 P Belongs to the nlpA lipoprotein family
NNMPHLEP_01077 3.9e-12
NNMPHLEP_01078 1.1e-222 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NNMPHLEP_01079 1.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NNMPHLEP_01080 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
NNMPHLEP_01081 1.7e-176 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NNMPHLEP_01082 5.9e-22 S Protein of unknown function (DUF3042)
NNMPHLEP_01083 3.4e-67 yqhL P Rhodanese-like protein
NNMPHLEP_01084 1.5e-183 glk 2.7.1.2 G Glucokinase
NNMPHLEP_01085 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NNMPHLEP_01086 2.7e-112 gluP 3.4.21.105 S Peptidase, S54 family
NNMPHLEP_01087 2.9e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NNMPHLEP_01088 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NNMPHLEP_01089 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NNMPHLEP_01090 0.0 S membrane
NNMPHLEP_01091 4.4e-70 yneR S Belongs to the HesB IscA family
NNMPHLEP_01092 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNMPHLEP_01093 2.5e-118 udk 2.7.1.48 F Cytidine monophosphokinase
NNMPHLEP_01094 4.3e-115 rlpA M PFAM NLP P60 protein
NNMPHLEP_01095 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNMPHLEP_01096 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NNMPHLEP_01097 6.7e-59 yodB K Transcriptional regulator, HxlR family
NNMPHLEP_01098 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NNMPHLEP_01099 4.8e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NNMPHLEP_01100 5e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NNMPHLEP_01101 9.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NNMPHLEP_01102 1.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NNMPHLEP_01103 6.3e-230 V MatE
NNMPHLEP_01104 1.9e-267 yjeM E Amino Acid
NNMPHLEP_01105 1.2e-277 arlS 2.7.13.3 T Histidine kinase
NNMPHLEP_01106 1.5e-121 K response regulator
NNMPHLEP_01107 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NNMPHLEP_01108 2.9e-99 yceD S Uncharacterized ACR, COG1399
NNMPHLEP_01109 1.6e-213 ylbM S Belongs to the UPF0348 family
NNMPHLEP_01110 3.9e-136 yqeM Q Methyltransferase
NNMPHLEP_01111 6.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NNMPHLEP_01112 3.5e-114 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NNMPHLEP_01113 2.4e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NNMPHLEP_01114 1.9e-47 yhbY J RNA-binding protein
NNMPHLEP_01115 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
NNMPHLEP_01116 4.8e-96 yqeG S HAD phosphatase, family IIIA
NNMPHLEP_01117 1.7e-119 pnb C nitroreductase
NNMPHLEP_01118 7.6e-89
NNMPHLEP_01119 3.7e-246 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NNMPHLEP_01120 5.2e-92 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NNMPHLEP_01122 1.9e-47
NNMPHLEP_01123 5.7e-155 cylA V ABC transporter
NNMPHLEP_01124 8.2e-146 cylB V ABC-2 type transporter
NNMPHLEP_01125 1.3e-73 K LytTr DNA-binding domain
NNMPHLEP_01126 1.5e-59 S Protein of unknown function (DUF3021)
NNMPHLEP_01128 2.4e-170 L Plasmid pRiA4b ORF-3-like protein
NNMPHLEP_01131 5.1e-82 padR K Transcriptional regulator PadR-like family
NNMPHLEP_01132 1.2e-246 norB EGP Major Facilitator
NNMPHLEP_01133 3.3e-106 1.6.5.2 S NADPH-dependent FMN reductase
NNMPHLEP_01134 4.4e-36 S ABC-2 family transporter protein
NNMPHLEP_01135 2.6e-47 V ABC transporter, ATP-binding protein
NNMPHLEP_01136 1.2e-28 V ABC transporter, ATP-binding protein
NNMPHLEP_01137 5.8e-54 yqkB S Belongs to the HesB IscA family
NNMPHLEP_01138 2.9e-20
NNMPHLEP_01139 2e-19
NNMPHLEP_01140 5.9e-18 K LytTr DNA-binding domain
NNMPHLEP_01141 1.1e-35 S Protein of unknown function (DUF3021)
NNMPHLEP_01142 8.2e-81 1.6.5.2 S NADPH-dependent FMN reductase
NNMPHLEP_01143 8.5e-64 K Bacterial regulatory proteins, tetR family
NNMPHLEP_01145 2.8e-59
NNMPHLEP_01146 4.4e-74 S Metallo-beta-lactamase superfamily
NNMPHLEP_01147 1.9e-51 K Psort location Cytoplasmic, score
NNMPHLEP_01148 2.2e-51 yjdF S Protein of unknown function (DUF2992)
NNMPHLEP_01149 2.3e-105 L Transposase
NNMPHLEP_01150 5.2e-119 xylR GK ROK family
NNMPHLEP_01152 1.3e-260 xylT EGP Major facilitator Superfamily
NNMPHLEP_01153 8.6e-173 rhaS2 K Transcriptional regulator, AraC family
NNMPHLEP_01154 1.6e-290 xynT G MFS/sugar transport protein
NNMPHLEP_01155 0.0 3.2.1.55 GH51 G Right handed beta helix region
NNMPHLEP_01156 3.1e-44 pgdA 3.5.1.104 G polysaccharide deacetylase
NNMPHLEP_01157 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
NNMPHLEP_01158 2e-271 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NNMPHLEP_01159 3.5e-301 xylB 2.7.1.17 G Belongs to the FGGY kinase family
NNMPHLEP_01160 1.4e-153 KT YcbB domain
NNMPHLEP_01161 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NNMPHLEP_01162 4.4e-169 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NNMPHLEP_01163 5.8e-158 EG EamA-like transporter family
NNMPHLEP_01164 7.7e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NNMPHLEP_01165 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NNMPHLEP_01166 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NNMPHLEP_01167 0.0 copA 3.6.3.54 P P-type ATPase
NNMPHLEP_01168 1.3e-87
NNMPHLEP_01170 3.6e-57
NNMPHLEP_01171 1.6e-251 yjcE P Sodium proton antiporter
NNMPHLEP_01173 3.5e-91
NNMPHLEP_01175 1.4e-65 T Toxin-antitoxin system, toxin component, MazF family
NNMPHLEP_01176 1e-37
NNMPHLEP_01178 0.0 snf 2.7.11.1 KL domain protein
NNMPHLEP_01179 3.1e-144 ywqE 3.1.3.48 GM PHP domain protein
NNMPHLEP_01180 4.4e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NNMPHLEP_01181 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NNMPHLEP_01182 2.3e-90 L nuclease
NNMPHLEP_01183 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NNMPHLEP_01184 2.1e-70
NNMPHLEP_01185 6.7e-104 fic D Fic/DOC family
NNMPHLEP_01186 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NNMPHLEP_01187 2.3e-148 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NNMPHLEP_01188 4.6e-30
NNMPHLEP_01189 1.6e-63
NNMPHLEP_01190 3.8e-94
NNMPHLEP_01191 3.5e-24
NNMPHLEP_01192 9.8e-32 ykzG S Belongs to the UPF0356 family
NNMPHLEP_01193 1.4e-81
NNMPHLEP_01194 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NNMPHLEP_01195 3.4e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NNMPHLEP_01196 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NNMPHLEP_01197 1.8e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NNMPHLEP_01198 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
NNMPHLEP_01199 3.9e-47 yktA S Belongs to the UPF0223 family
NNMPHLEP_01200 2.4e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NNMPHLEP_01201 0.0 typA T GTP-binding protein TypA
NNMPHLEP_01202 7e-223 ftsW D Belongs to the SEDS family
NNMPHLEP_01203 9.7e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NNMPHLEP_01204 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NNMPHLEP_01205 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NNMPHLEP_01206 7.1e-200 ylbL T Belongs to the peptidase S16 family
NNMPHLEP_01207 5.8e-80 comEA L Competence protein ComEA
NNMPHLEP_01208 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
NNMPHLEP_01209 0.0 comEC S Competence protein ComEC
NNMPHLEP_01210 3.8e-145 holA 2.7.7.7 L DNA polymerase III delta subunit
NNMPHLEP_01211 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
NNMPHLEP_01212 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NNMPHLEP_01213 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NNMPHLEP_01214 5.4e-31 XK27_00915 C Luciferase-like monooxygenase
NNMPHLEP_01215 3.9e-133 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NNMPHLEP_01216 6.2e-60 S Protein of unknown function (DUF3021)
NNMPHLEP_01217 4e-72 K LytTr DNA-binding domain
NNMPHLEP_01218 7.2e-21
NNMPHLEP_01219 2.4e-119 ybhL S Belongs to the BI1 family
NNMPHLEP_01220 1.3e-73 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NNMPHLEP_01221 1e-190 S Protein of unknown function (DUF3114)
NNMPHLEP_01222 4.2e-294 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NNMPHLEP_01223 7.7e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NNMPHLEP_01224 7.6e-103 yvdD 3.2.2.10 S Belongs to the LOG family
NNMPHLEP_01225 9.1e-62 S Domain of unknown function (DUF4828)
NNMPHLEP_01226 4.5e-191 mocA S Oxidoreductase
NNMPHLEP_01227 2.5e-231 yfmL L DEAD DEAH box helicase
NNMPHLEP_01229 9.9e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NNMPHLEP_01230 2.7e-55
NNMPHLEP_01231 1.5e-74 gtcA S Teichoic acid glycosylation protein
NNMPHLEP_01232 6.1e-79 fld C Flavodoxin
NNMPHLEP_01233 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
NNMPHLEP_01234 1.7e-220 arcT 2.6.1.1 E Aminotransferase
NNMPHLEP_01235 5.6e-256 E Arginine ornithine antiporter
NNMPHLEP_01236 5.7e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NNMPHLEP_01237 2.2e-103 proW P ABC transporter, permease protein
NNMPHLEP_01238 2.3e-139 proV E ABC transporter, ATP-binding protein
NNMPHLEP_01239 1.6e-109 proWZ P ABC transporter permease
NNMPHLEP_01240 6e-163 proX M ABC transporter, substrate-binding protein, QAT family
NNMPHLEP_01241 5.8e-74 K Transcriptional regulator
NNMPHLEP_01242 5.2e-215 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NNMPHLEP_01243 7.2e-309 cadA P P-type ATPase
NNMPHLEP_01244 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NNMPHLEP_01245 6.6e-125
NNMPHLEP_01246 3.3e-55 S Sugar efflux transporter for intercellular exchange
NNMPHLEP_01247 6.1e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NNMPHLEP_01249 0.0 L Helicase C-terminal domain protein
NNMPHLEP_01250 8.9e-84 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
NNMPHLEP_01251 1.7e-179 S Aldo keto reductase
NNMPHLEP_01254 4.4e-194 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NNMPHLEP_01255 1.5e-227 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NNMPHLEP_01256 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NNMPHLEP_01257 5.9e-155 asp3 S Accessory Sec secretory system ASP3
NNMPHLEP_01258 5e-215 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
NNMPHLEP_01259 6.2e-197 M transferase activity, transferring glycosyl groups
NNMPHLEP_01260 3e-162 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
NNMPHLEP_01261 3.5e-111 nss M transferase activity, transferring glycosyl groups
NNMPHLEP_01262 2.1e-75 M family 8
NNMPHLEP_01263 5.3e-09
NNMPHLEP_01264 1.1e-27 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NNMPHLEP_01265 5.2e-27 S YoeB-like toxin of bacterial type II toxin-antitoxin system
NNMPHLEP_01271 1.2e-08 K Helix-turn-helix XRE-family like proteins
NNMPHLEP_01272 1.4e-57 sip L Belongs to the 'phage' integrase family
NNMPHLEP_01273 3e-133 K response regulator
NNMPHLEP_01274 2.7e-269 yclK 2.7.13.3 T Histidine kinase
NNMPHLEP_01275 2e-155 glcU U sugar transport
NNMPHLEP_01276 4.4e-101 lacA 2.3.1.79 S Transferase hexapeptide repeat
NNMPHLEP_01277 2.5e-261 pgi 5.3.1.9 G Belongs to the GPI family
NNMPHLEP_01278 3.8e-28
NNMPHLEP_01279 3.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
NNMPHLEP_01280 7.5e-58 ytzB S Small secreted protein
NNMPHLEP_01281 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NNMPHLEP_01282 9.4e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NNMPHLEP_01283 1.2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NNMPHLEP_01284 9.3e-119 ybhL S Belongs to the BI1 family
NNMPHLEP_01285 1.4e-119 yoaK S Protein of unknown function (DUF1275)
NNMPHLEP_01286 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NNMPHLEP_01287 1.2e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NNMPHLEP_01288 4.5e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NNMPHLEP_01289 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NNMPHLEP_01290 1.3e-225 dnaB L replication initiation and membrane attachment
NNMPHLEP_01291 1.6e-171 dnaI L Primosomal protein DnaI
NNMPHLEP_01292 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NNMPHLEP_01293 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NNMPHLEP_01294 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NNMPHLEP_01295 1.6e-48 S Glycosyltransferase like family 2
NNMPHLEP_01296 2.1e-28 S Glycosyltransferase like family 2
NNMPHLEP_01297 1.9e-29 M PFAM Glycosyl transferase family 2
NNMPHLEP_01298 1.2e-28 M Glycosyltransferase sugar-binding region containing DXD motif
NNMPHLEP_01299 1.3e-72 cps2I S Psort location CytoplasmicMembrane, score
NNMPHLEP_01301 7e-42 M cog cog1442
NNMPHLEP_01302 8.8e-67 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
NNMPHLEP_01303 3.1e-87 GT4 G Glycosyl transferase 4-like
NNMPHLEP_01304 1.5e-48 pglC M Bacterial sugar transferase
NNMPHLEP_01305 6.6e-107 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NNMPHLEP_01306 2e-98 epsB M biosynthesis protein
NNMPHLEP_01307 1.4e-178 S Hydrolases of the alpha beta superfamily
NNMPHLEP_01308 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
NNMPHLEP_01309 4.4e-77 ctsR K Belongs to the CtsR family
NNMPHLEP_01310 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NNMPHLEP_01311 1e-110 K Bacterial regulatory proteins, tetR family
NNMPHLEP_01312 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNMPHLEP_01313 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNMPHLEP_01314 2.3e-199 ykiI
NNMPHLEP_01315 3.4e-118 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NNMPHLEP_01316 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NNMPHLEP_01317 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NNMPHLEP_01318 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NNMPHLEP_01319 3.5e-163 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NNMPHLEP_01320 2.1e-32 L Transposase
NNMPHLEP_01321 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NNMPHLEP_01322 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NNMPHLEP_01323 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
NNMPHLEP_01324 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NNMPHLEP_01325 5.4e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NNMPHLEP_01326 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NNMPHLEP_01327 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NNMPHLEP_01328 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NNMPHLEP_01329 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NNMPHLEP_01330 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
NNMPHLEP_01331 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NNMPHLEP_01332 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NNMPHLEP_01333 7.5e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NNMPHLEP_01334 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NNMPHLEP_01335 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NNMPHLEP_01336 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NNMPHLEP_01337 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NNMPHLEP_01338 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NNMPHLEP_01339 2.9e-24 rpmD J Ribosomal protein L30
NNMPHLEP_01340 8.9e-64 rplO J Binds to the 23S rRNA
NNMPHLEP_01341 4.4e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NNMPHLEP_01342 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NNMPHLEP_01343 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NNMPHLEP_01344 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NNMPHLEP_01345 3.6e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NNMPHLEP_01346 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NNMPHLEP_01347 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NNMPHLEP_01348 1.1e-62 rplQ J Ribosomal protein L17
NNMPHLEP_01349 5.2e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNMPHLEP_01350 2.9e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNMPHLEP_01351 1.3e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NNMPHLEP_01352 1.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NNMPHLEP_01353 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NNMPHLEP_01354 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NNMPHLEP_01355 2.1e-140 IQ reductase
NNMPHLEP_01356 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
NNMPHLEP_01357 3.5e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NNMPHLEP_01358 5.1e-212 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NNMPHLEP_01359 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NNMPHLEP_01360 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NNMPHLEP_01361 1.2e-202 camS S sex pheromone
NNMPHLEP_01362 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNMPHLEP_01363 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NNMPHLEP_01364 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NNMPHLEP_01365 2.5e-186 yegS 2.7.1.107 G Lipid kinase
NNMPHLEP_01366 3.1e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NNMPHLEP_01367 1.2e-126 L Mrr N-terminal domain
NNMPHLEP_01368 1.3e-290 L Recombinase
NNMPHLEP_01369 3.4e-289 L Recombinase zinc beta ribbon domain
NNMPHLEP_01370 1.2e-30
NNMPHLEP_01371 1.2e-131 M Glycosyl hydrolases family 25
NNMPHLEP_01372 9.7e-68 S Bacteriophage holin family
NNMPHLEP_01373 1.9e-65 S Phage head-tail joining protein
NNMPHLEP_01374 3.7e-39 S Phage gp6-like head-tail connector protein
NNMPHLEP_01375 1.9e-209 S Phage capsid family
NNMPHLEP_01376 5e-114 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NNMPHLEP_01377 7.4e-244 S Phage portal protein
NNMPHLEP_01378 1.7e-306 S overlaps another CDS with the same product name
NNMPHLEP_01379 2.8e-31 S Domain of unknown function (DUF5049)
NNMPHLEP_01380 3.2e-115 S Psort location Cytoplasmic, score
NNMPHLEP_01381 1e-237 2.1.1.72 KL DNA methylase
NNMPHLEP_01382 1.1e-98
NNMPHLEP_01383 3.8e-71 V HNH nucleases
NNMPHLEP_01384 1.6e-82
NNMPHLEP_01385 9.4e-253 L SNF2 family N-terminal domain
NNMPHLEP_01386 2.4e-46 S VRR_NUC
NNMPHLEP_01387 0.0 S Phage plasmid primase, P4
NNMPHLEP_01388 7.4e-70 S Psort location Cytoplasmic, score
NNMPHLEP_01389 0.0 polA_2 2.7.7.7 L DNA polymerase
NNMPHLEP_01390 3.2e-98 S Protein of unknown function (DUF2815)
NNMPHLEP_01391 3e-212 L Protein of unknown function (DUF2800)
NNMPHLEP_01392 4.7e-38
NNMPHLEP_01393 6.1e-23
NNMPHLEP_01394 4.2e-72 K DNA-templated transcription, initiation
NNMPHLEP_01395 2e-19 S Domain of unknown function (DUF1837)
NNMPHLEP_01396 6.9e-111 L helicase
NNMPHLEP_01397 4e-114 3.6.4.12 L ATP-dependent DNA helicase (RecQ)
NNMPHLEP_01398 2.3e-81 2.1.1.113, 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NNMPHLEP_01399 2.6e-45 L COG1743 Adenine-specific DNA methylase containing a Zn-ribbon
NNMPHLEP_01400 2.2e-201 L PFAM transposase, IS4 family protein
NNMPHLEP_01401 4.3e-63 S Bacteriophage abortive infection AbiH
NNMPHLEP_01402 4.8e-102
NNMPHLEP_01403 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NNMPHLEP_01404 1.1e-33 copZ C Heavy-metal-associated domain
NNMPHLEP_01405 1.6e-94 dps P Belongs to the Dps family
NNMPHLEP_01406 9.9e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NNMPHLEP_01407 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
NNMPHLEP_01408 1.4e-33 5.1.1.13 M Asp/Glu/Hydantoin racemase
NNMPHLEP_01409 5.9e-74 5.1.1.13 M Asp/Glu/Hydantoin racemase
NNMPHLEP_01410 4.8e-52 L Transposase
NNMPHLEP_01411 2e-118 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
NNMPHLEP_01412 4.7e-43 mleP3 S Membrane transport protein
NNMPHLEP_01413 8.1e-120 T Transcriptional regulatory protein, C terminal
NNMPHLEP_01414 2.8e-241 T GHKL domain
NNMPHLEP_01415 1.5e-99 S Peptidase propeptide and YPEB domain
NNMPHLEP_01416 3.8e-134 K LytTr DNA-binding domain
NNMPHLEP_01417 1.2e-204 2.7.13.3 T GHKL domain
NNMPHLEP_01420 1.5e-87 V Beta-lactamase
NNMPHLEP_01421 2.5e-52 yphJ 4.1.1.44 S decarboxylase
NNMPHLEP_01422 3.6e-165 S Oxidoreductase, aldo keto reductase family protein
NNMPHLEP_01423 2.6e-80 C Flavodoxin
NNMPHLEP_01424 3.1e-156 K Transcriptional regulator
NNMPHLEP_01425 1.9e-113 L Integrase core domain
NNMPHLEP_01426 9e-283 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NNMPHLEP_01427 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NNMPHLEP_01428 1.7e-75 L hmm pf00665
NNMPHLEP_01429 1.3e-69 L hmm pf00665
NNMPHLEP_01431 3.6e-68 K Bacterial regulatory proteins, tetR family
NNMPHLEP_01432 2.1e-37 S Domain of unknown function (DUF4440)
NNMPHLEP_01433 3.7e-202 qacA EGP Fungal trichothecene efflux pump (TRI12)
NNMPHLEP_01434 3.6e-41 S Hexapeptide repeat of succinyl-transferase
NNMPHLEP_01435 9.5e-126 C Aldo keto reductase
NNMPHLEP_01436 8.6e-89 GM NAD(P)H-binding
NNMPHLEP_01437 1.7e-138 akr5f 1.1.1.346 S reductase
NNMPHLEP_01438 2.5e-186 L Helix-turn-helix domain
NNMPHLEP_01439 1.6e-112 ywnB S NAD(P)H-binding
NNMPHLEP_01440 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
NNMPHLEP_01441 4.5e-258 nhaC C Na H antiporter NhaC
NNMPHLEP_01442 5.4e-184 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NNMPHLEP_01444 8.7e-89
NNMPHLEP_01445 1.6e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NNMPHLEP_01446 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NNMPHLEP_01447 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NNMPHLEP_01448 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NNMPHLEP_01449 1e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NNMPHLEP_01450 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NNMPHLEP_01451 4.9e-08
NNMPHLEP_01452 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NNMPHLEP_01453 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
NNMPHLEP_01454 6.9e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NNMPHLEP_01455 1.3e-114 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NNMPHLEP_01457 6.2e-54 S GyrI-like small molecule binding domain
NNMPHLEP_01458 5e-16 S GyrI-like small molecule binding domain
NNMPHLEP_01459 8e-120 yhiD S MgtC family
NNMPHLEP_01460 2.8e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NNMPHLEP_01461 5.3e-192 V Beta-lactamase
NNMPHLEP_01462 2.4e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NNMPHLEP_01463 1.8e-89 XK27_08850 J Aminoacyl-tRNA editing domain
NNMPHLEP_01464 7.6e-20 relB L Addiction module antitoxin, RelB DinJ family
NNMPHLEP_01465 8.9e-24
NNMPHLEP_01466 5.8e-289 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NNMPHLEP_01467 8.6e-118 K LytTr DNA-binding domain
NNMPHLEP_01468 1.6e-129 2.7.13.3 T GHKL domain
NNMPHLEP_01470 1.1e-239 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NNMPHLEP_01471 7.5e-49 czrA K Transcriptional regulator, ArsR family
NNMPHLEP_01472 5.1e-37
NNMPHLEP_01473 0.0 yhcA V ABC transporter, ATP-binding protein
NNMPHLEP_01474 3.9e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NNMPHLEP_01475 7e-171 hrtB V ABC transporter permease
NNMPHLEP_01476 4.4e-86 ygfC K transcriptional regulator (TetR family)
NNMPHLEP_01477 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NNMPHLEP_01478 3.3e-289 mntH P H( )-stimulated, divalent metal cation uptake system
NNMPHLEP_01479 2e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NNMPHLEP_01480 3.9e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NNMPHLEP_01481 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
NNMPHLEP_01482 1.2e-114 yjbH Q Thioredoxin
NNMPHLEP_01483 1.7e-265 pipD E Dipeptidase
NNMPHLEP_01484 1e-203 coiA 3.6.4.12 S Competence protein
NNMPHLEP_01485 5.2e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NNMPHLEP_01486 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NNMPHLEP_01487 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NNMPHLEP_01508 1.6e-106
NNMPHLEP_01509 2.2e-213 yttB EGP Major facilitator Superfamily
NNMPHLEP_01510 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NNMPHLEP_01511 1.3e-87
NNMPHLEP_01512 1.9e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NNMPHLEP_01513 9.9e-258 S Putative peptidoglycan binding domain
NNMPHLEP_01514 1.2e-14
NNMPHLEP_01515 1.4e-121 yciB M ErfK YbiS YcfS YnhG
NNMPHLEP_01517 3e-99
NNMPHLEP_01518 1.1e-215 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NNMPHLEP_01519 8e-125 S Alpha beta hydrolase
NNMPHLEP_01520 1.1e-104 yocS S SBF-like CPA transporter family (DUF4137)
NNMPHLEP_01521 1.4e-129 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NNMPHLEP_01522 7.1e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NNMPHLEP_01523 1.2e-230 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NNMPHLEP_01524 5.1e-207 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NNMPHLEP_01525 1.3e-205 ydiN G Major Facilitator Superfamily
NNMPHLEP_01526 1.4e-155 menH 2.2.1.9, 4.2.99.20, 6.2.1.26 I Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NNMPHLEP_01527 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NNMPHLEP_01528 9.6e-250 menF 5.4.4.2 HQ chorismate binding enzyme
NNMPHLEP_01529 5.2e-87 comP 2.7.13.3 F Sensor histidine kinase
NNMPHLEP_01530 2.3e-116 nreC K PFAM regulatory protein LuxR
NNMPHLEP_01531 4.6e-18
NNMPHLEP_01532 1.8e-181
NNMPHLEP_01533 3.8e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
NNMPHLEP_01534 3.9e-218 narK P Transporter, major facilitator family protein
NNMPHLEP_01535 1.7e-35 moaD 2.8.1.12 H ThiS family
NNMPHLEP_01536 2.2e-64 moaE 2.8.1.12 H MoaE protein
NNMPHLEP_01537 6.6e-78 S Flavodoxin
NNMPHLEP_01538 2e-130 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NNMPHLEP_01539 1.4e-139 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
NNMPHLEP_01540 2.1e-166 cpsY K Transcriptional regulator, LysR family
NNMPHLEP_01541 1.6e-103 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NNMPHLEP_01542 4.4e-272 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NNMPHLEP_01543 7.3e-155 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
NNMPHLEP_01544 4.2e-52 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NNMPHLEP_01545 1.8e-55 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NNMPHLEP_01547 3.2e-220 L transposase IS116 IS110 IS902 family protein
NNMPHLEP_01548 2.9e-151 L Transposase
NNMPHLEP_01549 1e-69 L Transposase
NNMPHLEP_01550 2.1e-34 L PFAM Integrase catalytic region
NNMPHLEP_01551 3.2e-153 spoU 2.1.1.185 J Methyltransferase
NNMPHLEP_01552 1.2e-80 pnuC H nicotinamide mononucleotide transporter
NNMPHLEP_01553 1.9e-200 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NNMPHLEP_01554 7.1e-101 ywlG S Belongs to the UPF0340 family
NNMPHLEP_01555 1.5e-198 EGP Major facilitator Superfamily
NNMPHLEP_01556 5.9e-101 M Lysin motif
NNMPHLEP_01557 4.7e-79
NNMPHLEP_01558 2.8e-168 P CorA-like Mg2+ transporter protein
NNMPHLEP_01559 3.1e-95 wecD3 K PFAM GCN5-related N-acetyltransferase
NNMPHLEP_01560 3.8e-202 cytX U Belongs to the purine-cytosine permease (2.A.39) family
NNMPHLEP_01561 4.3e-13
NNMPHLEP_01562 1.5e-77 S Domain of unknown function (DUF4767)
NNMPHLEP_01563 4.1e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NNMPHLEP_01564 1.1e-112 S Membrane
NNMPHLEP_01565 6e-123 O Zinc-dependent metalloprotease
NNMPHLEP_01566 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NNMPHLEP_01567 5e-159 metQ_4 P Belongs to the nlpA lipoprotein family
NNMPHLEP_01569 0.0 UW LPXTG-motif cell wall anchor domain protein
NNMPHLEP_01570 5.5e-197 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NNMPHLEP_01571 4.9e-183 S Phosphotransferase system, EIIC
NNMPHLEP_01572 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NNMPHLEP_01573 5.5e-165
NNMPHLEP_01575 3.7e-70 manA 5.3.1.8 G mannose-6-phosphate isomerase
NNMPHLEP_01576 1.2e-94 2.3.1.128 K acetyltransferase
NNMPHLEP_01577 7e-168
NNMPHLEP_01578 1.7e-13 K Transcriptional regulator, HxlR family
NNMPHLEP_01579 2.1e-216 P ammonium transporter
NNMPHLEP_01580 4.4e-94 ureI S AmiS/UreI family transporter
NNMPHLEP_01581 6.5e-45 ureA 3.5.1.5 E Urease, gamma subunit
NNMPHLEP_01582 7.7e-64 ureB 3.5.1.5 E Urease beta subunit
NNMPHLEP_01583 0.0 ureC 3.5.1.5 E Amidohydrolase family
NNMPHLEP_01584 3.3e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NNMPHLEP_01585 6.2e-131 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NNMPHLEP_01586 1.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NNMPHLEP_01587 2.4e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NNMPHLEP_01588 5.5e-41 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNMPHLEP_01589 4.5e-73 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNMPHLEP_01590 5.7e-186 nikMN P PDGLE domain
NNMPHLEP_01591 3.9e-132 P Cobalt transport protein
NNMPHLEP_01592 8.6e-136 cbiO P ABC transporter
NNMPHLEP_01593 3e-133 K Transcriptional regulatory protein, C-terminal domain protein
NNMPHLEP_01594 1.2e-155 pstS P Phosphate
NNMPHLEP_01595 4.7e-152 pstC P probably responsible for the translocation of the substrate across the membrane
NNMPHLEP_01596 1.4e-153 pstA P Phosphate transport system permease protein PstA
NNMPHLEP_01597 2.3e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NNMPHLEP_01598 2.1e-123 phoU P Plays a role in the regulation of phosphate uptake
NNMPHLEP_01599 3.6e-217 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
NNMPHLEP_01600 7.6e-115
NNMPHLEP_01602 1.5e-210 ydaM M Glycosyl transferase
NNMPHLEP_01603 3.6e-165 G Glycosyl hydrolases family 8
NNMPHLEP_01604 1.5e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NNMPHLEP_01605 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NNMPHLEP_01606 6.5e-238 ktrB P Potassium uptake protein
NNMPHLEP_01607 1.4e-116 ktrA P domain protein
NNMPHLEP_01608 1e-80 Q Methyltransferase
NNMPHLEP_01609 3e-232 mntH P H( )-stimulated, divalent metal cation uptake system
NNMPHLEP_01610 2.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NNMPHLEP_01611 2.2e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NNMPHLEP_01613 4.6e-86 S NADPH-dependent FMN reductase
NNMPHLEP_01614 3.6e-172 MA20_14895 S Conserved hypothetical protein 698
NNMPHLEP_01615 6.8e-167 L transposase, IS605 OrfB family
NNMPHLEP_01616 1.2e-110 I alpha/beta hydrolase fold
NNMPHLEP_01617 1.3e-128 lsa S ABC transporter
NNMPHLEP_01618 5.7e-172 yfeX P Peroxidase
NNMPHLEP_01619 7e-273 arcD S C4-dicarboxylate anaerobic carrier
NNMPHLEP_01620 4.3e-258 ytjP 3.5.1.18 E Dipeptidase
NNMPHLEP_01621 5.9e-214 uhpT EGP Major facilitator Superfamily
NNMPHLEP_01622 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NNMPHLEP_01623 5e-129 ponA V Beta-lactamase enzyme family
NNMPHLEP_01624 3.4e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NNMPHLEP_01625 4.3e-74
NNMPHLEP_01626 9e-37 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NNMPHLEP_01627 9.4e-39 trxA O Belongs to the thioredoxin family
NNMPHLEP_01629 1e-95 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NNMPHLEP_01630 1.2e-139 trxB 1.8.1.9 O Glucose inhibited division protein A
NNMPHLEP_01631 2.8e-24 CO cell redox homeostasis
NNMPHLEP_01632 1.4e-70 M1-798 K Rhodanese Homology Domain
NNMPHLEP_01633 5.1e-42 K HxlR-like helix-turn-helix
NNMPHLEP_01634 1.9e-138 L Bacterial dnaA protein
NNMPHLEP_01635 1.3e-204 L Integrase core domain
NNMPHLEP_01637 1.2e-30 K helix_turn_helix, mercury resistance
NNMPHLEP_01638 3e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNMPHLEP_01639 2.2e-194 EGP Major facilitator Superfamily
NNMPHLEP_01640 9.6e-86 ymdB S Macro domain protein
NNMPHLEP_01641 1.9e-110 K Helix-turn-helix domain
NNMPHLEP_01642 0.0 pepO 3.4.24.71 O Peptidase family M13
NNMPHLEP_01643 3.5e-42
NNMPHLEP_01644 5.8e-83
NNMPHLEP_01645 4.6e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NNMPHLEP_01646 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NNMPHLEP_01647 0.0 yjbQ P TrkA C-terminal domain protein
NNMPHLEP_01648 2.1e-70 pipD E Dipeptidase
NNMPHLEP_01649 1.2e-188 pipD E Dipeptidase
NNMPHLEP_01651 6.8e-52 pglC M Bacterial sugar transferase
NNMPHLEP_01652 3.2e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NNMPHLEP_01653 2.5e-137 epsB M biosynthesis protein
NNMPHLEP_01654 1.6e-161 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NNMPHLEP_01655 1.6e-67 K Transcriptional regulator, HxlR family
NNMPHLEP_01656 1.5e-127
NNMPHLEP_01657 5.8e-103 K DNA-templated transcription, initiation
NNMPHLEP_01658 2.8e-35
NNMPHLEP_01659 1.2e-234 lmrB EGP Major facilitator Superfamily
NNMPHLEP_01660 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NNMPHLEP_01661 2.4e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NNMPHLEP_01662 1.2e-155 sufD O Uncharacterized protein family (UPF0051)
NNMPHLEP_01663 1.3e-19 WQ51_00220 K Helix-turn-helix domain
NNMPHLEP_01664 6.3e-101 L Transposase
NNMPHLEP_01665 1.4e-71 natA S Domain of unknown function (DUF4162)
NNMPHLEP_01666 3.5e-44 ysdA CP transmembrane transport
NNMPHLEP_01668 2.3e-41 O Bacterial dnaA protein
NNMPHLEP_01669 1.2e-12 K Transcriptional
NNMPHLEP_01670 4.4e-90 L Integrase
NNMPHLEP_01671 7.1e-86 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NNMPHLEP_01672 2.9e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NNMPHLEP_01673 3.5e-55 yitW S Pfam:DUF59
NNMPHLEP_01674 4.4e-32 L PFAM Integrase catalytic region
NNMPHLEP_01675 1.9e-104 L Belongs to the 'phage' integrase family
NNMPHLEP_01676 2.7e-224 L Transposase IS66 family
NNMPHLEP_01677 8.5e-42 L Transposase IS66 family
NNMPHLEP_01678 1.9e-52 XK27_01125 L PFAM IS66 Orf2 family protein
NNMPHLEP_01690 2.2e-19 D COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NNMPHLEP_01691 1.8e-80 L Replication protein
NNMPHLEP_01694 8.5e-39 L Integrase core domain
NNMPHLEP_01695 4.2e-37 mrr L restriction endonuclease
NNMPHLEP_01696 0.0 L PLD-like domain
NNMPHLEP_01698 1.3e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NNMPHLEP_01699 9.4e-192 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NNMPHLEP_01700 2.5e-96 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NNMPHLEP_01701 1.2e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NNMPHLEP_01702 4.4e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NNMPHLEP_01703 8.6e-104 T Ion transport 2 domain protein
NNMPHLEP_01704 0.0 S Bacterial membrane protein YfhO
NNMPHLEP_01705 7.8e-203 G Transporter, major facilitator family protein
NNMPHLEP_01706 1.6e-108 yvrI K RNA polymerase sigma factor, sigma-70 family
NNMPHLEP_01707 1.2e-64 ydiI Q Thioesterase superfamily
NNMPHLEP_01708 1.9e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NNMPHLEP_01709 5.7e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NNMPHLEP_01710 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NNMPHLEP_01711 4.2e-32 feoA P FeoA domain
NNMPHLEP_01712 6.5e-145 sufC O FeS assembly ATPase SufC
NNMPHLEP_01713 3.9e-240 sufD O FeS assembly protein SufD
NNMPHLEP_01714 3.3e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NNMPHLEP_01715 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
NNMPHLEP_01716 3e-270 sufB O assembly protein SufB
NNMPHLEP_01717 2.4e-56 yitW S Iron-sulfur cluster assembly protein
NNMPHLEP_01718 1.4e-159 hipB K Helix-turn-helix
NNMPHLEP_01719 1.6e-112 nreC K PFAM regulatory protein LuxR
NNMPHLEP_01720 9.2e-39 S Cytochrome B5
NNMPHLEP_01721 1.2e-154 yitU 3.1.3.104 S hydrolase
NNMPHLEP_01722 7.7e-263 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NNMPHLEP_01723 1.8e-148 f42a O Band 7 protein
NNMPHLEP_01724 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
NNMPHLEP_01725 4.1e-130 lytT K response regulator receiver
NNMPHLEP_01726 1.9e-66 lrgA S LrgA family
NNMPHLEP_01727 1.3e-123 lrgB M LrgB-like family
NNMPHLEP_01728 2.1e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NNMPHLEP_01729 6.2e-173 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NNMPHLEP_01730 1.4e-184 galR K Periplasmic binding protein-like domain
NNMPHLEP_01731 0.0 rafA 3.2.1.22 G alpha-galactosidase
NNMPHLEP_01732 4.9e-87 S Protein of unknown function (DUF1440)
NNMPHLEP_01733 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NNMPHLEP_01734 4.6e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NNMPHLEP_01735 4e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NNMPHLEP_01736 3.3e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NNMPHLEP_01737 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NNMPHLEP_01738 4e-87 ypmB S Protein conserved in bacteria
NNMPHLEP_01739 4.7e-123 dnaD L DnaD domain protein
NNMPHLEP_01740 7.4e-161 EG EamA-like transporter family
NNMPHLEP_01741 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NNMPHLEP_01742 3.7e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NNMPHLEP_01743 2.6e-103 ypsA S Belongs to the UPF0398 family
NNMPHLEP_01744 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NNMPHLEP_01745 1.1e-83 F Belongs to the NrdI family
NNMPHLEP_01746 3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NNMPHLEP_01747 4e-71 rnhA 3.1.26.4 L Ribonuclease HI
NNMPHLEP_01748 1.5e-65 esbA S Family of unknown function (DUF5322)
NNMPHLEP_01749 2e-71 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NNMPHLEP_01750 1.1e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NNMPHLEP_01751 2.4e-206 carA 6.3.5.5 F Belongs to the CarA family
NNMPHLEP_01752 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NNMPHLEP_01753 0.0 FbpA K Fibronectin-binding protein
NNMPHLEP_01754 6.4e-162 degV S EDD domain protein, DegV family
NNMPHLEP_01755 9.4e-94
NNMPHLEP_01756 8.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NNMPHLEP_01757 1.9e-135 gspA M family 8
NNMPHLEP_01758 1.2e-160 S Alpha beta hydrolase
NNMPHLEP_01759 6.9e-95 K Acetyltransferase (GNAT) domain
NNMPHLEP_01760 1.9e-125 XK27_08635 S UPF0210 protein
NNMPHLEP_01761 8.5e-55 XK27_08635 S UPF0210 protein
NNMPHLEP_01762 1e-17 XK27_08635 S UPF0210 protein
NNMPHLEP_01763 3.6e-39 gcvR T Belongs to the UPF0237 family
NNMPHLEP_01764 2.6e-166 1.1.1.346 C Aldo keto reductase
NNMPHLEP_01765 1.8e-41 K Transcriptional regulator
NNMPHLEP_01766 9.4e-79 yphH S Cupin domain
NNMPHLEP_01767 4.5e-74 yeaL S UPF0756 membrane protein
NNMPHLEP_01768 2.4e-243 EGP Major facilitator Superfamily
NNMPHLEP_01769 5e-75 copY K Copper transport repressor CopY TcrY
NNMPHLEP_01770 1.9e-245 yhdP S Transporter associated domain
NNMPHLEP_01771 0.0 ubiB S ABC1 family
NNMPHLEP_01772 2.9e-140 S DUF218 domain
NNMPHLEP_01773 2.1e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NNMPHLEP_01774 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNMPHLEP_01775 2.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NNMPHLEP_01776 0.0 uvrA3 L excinuclease ABC, A subunit
NNMPHLEP_01777 3e-122 S SNARE associated Golgi protein
NNMPHLEP_01778 4.6e-230 N Uncharacterized conserved protein (DUF2075)
NNMPHLEP_01779 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NNMPHLEP_01781 3e-254 yifK E Amino acid permease
NNMPHLEP_01782 8.2e-154 endA V DNA/RNA non-specific endonuclease
NNMPHLEP_01783 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NNMPHLEP_01784 1.3e-41 ybaN S Protein of unknown function (DUF454)
NNMPHLEP_01785 4.5e-71 S Protein of unknown function (DUF3290)
NNMPHLEP_01786 6.2e-114 yviA S Protein of unknown function (DUF421)
NNMPHLEP_01787 3e-164 S Alpha/beta hydrolase of unknown function (DUF915)
NNMPHLEP_01788 3.4e-21
NNMPHLEP_01789 2.1e-90 ntd 2.4.2.6 F Nucleoside
NNMPHLEP_01790 1.9e-161 S Tetratricopeptide repeat
NNMPHLEP_01791 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NNMPHLEP_01792 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NNMPHLEP_01793 1.2e-76
NNMPHLEP_01794 9.8e-180
NNMPHLEP_01795 1.4e-181 fecB P Periplasmic binding protein
NNMPHLEP_01796 1.5e-29 S Acyltransferase family
NNMPHLEP_01801 2.1e-18 L Transposase
NNMPHLEP_01802 8e-189 L Transposase
NNMPHLEP_01803 9.9e-157 L hmm pf00665
NNMPHLEP_01804 1.9e-127 L Helix-turn-helix domain
NNMPHLEP_01805 3.2e-87 L Helix-turn-helix domain
NNMPHLEP_01806 6.3e-11 L hmm pf00665
NNMPHLEP_01807 6.3e-115 L hmm pf00665
NNMPHLEP_01808 8.3e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NNMPHLEP_01809 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NNMPHLEP_01810 0.0 araB 2.7.1.16 G carbohydrate kinase FGGY
NNMPHLEP_01811 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NNMPHLEP_01812 9.7e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NNMPHLEP_01813 3.5e-92 maa 2.3.1.79 S Maltose O-acetyltransferase
NNMPHLEP_01814 2.5e-155 ytbE 1.1.1.346 S Aldo keto reductase
NNMPHLEP_01815 1.3e-204 araR K Transcriptional regulator
NNMPHLEP_01816 4.3e-83 usp6 T universal stress protein
NNMPHLEP_01817 1.7e-45
NNMPHLEP_01818 1.3e-240 rarA L recombination factor protein RarA
NNMPHLEP_01819 2.5e-86 yueI S Protein of unknown function (DUF1694)
NNMPHLEP_01820 2e-21
NNMPHLEP_01821 3.1e-74 4.4.1.5 E Glyoxalase
NNMPHLEP_01822 1.2e-137 S Membrane
NNMPHLEP_01823 2.6e-135 S Belongs to the UPF0246 family
NNMPHLEP_01824 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NNMPHLEP_01825 8.3e-262 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NNMPHLEP_01826 1.3e-235 pbuG S permease
NNMPHLEP_01827 3.8e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NNMPHLEP_01828 4.3e-286 gadC E amino acid
NNMPHLEP_01829 1.1e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
NNMPHLEP_01830 6.9e-292 gadC E amino acid
NNMPHLEP_01831 8.2e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NNMPHLEP_01832 3.7e-238 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NNMPHLEP_01833 1.5e-214 iscS2 2.8.1.7 E Aminotransferase class V
NNMPHLEP_01834 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NNMPHLEP_01835 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NNMPHLEP_01836 3.6e-271 cydA 1.10.3.14 C ubiquinol oxidase
NNMPHLEP_01837 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NNMPHLEP_01838 4.8e-307 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NNMPHLEP_01839 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NNMPHLEP_01840 5e-229 ndh 1.6.99.3 C NADH dehydrogenase
NNMPHLEP_01841 4.4e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NNMPHLEP_01842 1e-121 radC L DNA repair protein
NNMPHLEP_01843 1.7e-179 mreB D cell shape determining protein MreB
NNMPHLEP_01844 7.7e-152 mreC M Involved in formation and maintenance of cell shape
NNMPHLEP_01845 8.7e-93 mreD M rod shape-determining protein MreD
NNMPHLEP_01846 3.2e-102 glnP P ABC transporter permease
NNMPHLEP_01847 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NNMPHLEP_01848 2.6e-160 aatB ET ABC transporter substrate-binding protein
NNMPHLEP_01849 8.7e-229 ymfF S Peptidase M16 inactive domain protein
NNMPHLEP_01850 1.8e-248 ymfH S Peptidase M16
NNMPHLEP_01851 9.9e-138 ymfM S Helix-turn-helix domain
NNMPHLEP_01852 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NNMPHLEP_01853 1.7e-229 cinA 3.5.1.42 S Belongs to the CinA family
NNMPHLEP_01854 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NNMPHLEP_01855 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
NNMPHLEP_01856 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NNMPHLEP_01857 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NNMPHLEP_01858 6.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NNMPHLEP_01859 4.5e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NNMPHLEP_01860 2.2e-196 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NNMPHLEP_01861 7.9e-31 yajC U Preprotein translocase
NNMPHLEP_01862 1.2e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NNMPHLEP_01863 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NNMPHLEP_01864 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NNMPHLEP_01865 4.1e-43 yrzL S Belongs to the UPF0297 family
NNMPHLEP_01866 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NNMPHLEP_01867 6.1e-48 yrzB S Belongs to the UPF0473 family
NNMPHLEP_01868 1e-85 cvpA S Colicin V production protein
NNMPHLEP_01869 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NNMPHLEP_01870 6.1e-54 trxA O Belongs to the thioredoxin family
NNMPHLEP_01871 1.3e-96 yslB S Protein of unknown function (DUF2507)
NNMPHLEP_01872 1.3e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NNMPHLEP_01873 2.4e-104 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NNMPHLEP_01874 2e-94 S Phosphoesterase
NNMPHLEP_01875 3.6e-76 ykuL S (CBS) domain
NNMPHLEP_01876 5.6e-155 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NNMPHLEP_01877 1.5e-147 ykuT M mechanosensitive ion channel
NNMPHLEP_01878 1.9e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NNMPHLEP_01879 4.9e-20
NNMPHLEP_01880 1.2e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NNMPHLEP_01881 4.5e-183 ccpA K catabolite control protein A
NNMPHLEP_01882 2.5e-134
NNMPHLEP_01883 1e-131 yebC K Transcriptional regulatory protein
NNMPHLEP_01884 4.3e-183 comGA NU Type II IV secretion system protein
NNMPHLEP_01885 1.2e-180 comGB NU type II secretion system
NNMPHLEP_01886 5.4e-47 comGC U competence protein ComGC
NNMPHLEP_01887 4.1e-77 NU general secretion pathway protein
NNMPHLEP_01888 7.1e-41
NNMPHLEP_01889 2.4e-69
NNMPHLEP_01890 1.3e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
NNMPHLEP_01891 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NNMPHLEP_01892 5.7e-117 S Calcineurin-like phosphoesterase
NNMPHLEP_01893 5.7e-100 yutD S Protein of unknown function (DUF1027)
NNMPHLEP_01894 1.8e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NNMPHLEP_01895 4.1e-113 S Protein of unknown function (DUF1461)
NNMPHLEP_01896 2.1e-109 dedA S SNARE-like domain protein
NNMPHLEP_01897 8.7e-173 scrR K Transcriptional regulator, LacI family
NNMPHLEP_01898 1e-24
NNMPHLEP_01899 1.9e-31 psiE S Phosphate-starvation-inducible E
NNMPHLEP_01900 3.9e-101 ydeN S Serine hydrolase
NNMPHLEP_01902 1.2e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NNMPHLEP_01904 1e-218 S Uncharacterised protein family (UPF0236)
NNMPHLEP_01905 1.4e-44 L Transposase
NNMPHLEP_01906 4.1e-36 M Glycosyl transferase, family 2
NNMPHLEP_01907 2.7e-08 MA20_43635 M Capsular polysaccharide synthesis protein
NNMPHLEP_01908 1.5e-133 S membrane transporter protein
NNMPHLEP_01909 4.6e-97 S ABC-type cobalt transport system, permease component
NNMPHLEP_01910 2.4e-251 cbiO1 S ABC transporter, ATP-binding protein
NNMPHLEP_01911 2.8e-114 P Cobalt transport protein
NNMPHLEP_01912 1.6e-52 yvlA
NNMPHLEP_01913 0.0 yjcE P Sodium proton antiporter
NNMPHLEP_01914 3.8e-52 ypaA S Protein of unknown function (DUF1304)
NNMPHLEP_01915 1.1e-189 D Alpha beta
NNMPHLEP_01916 1e-72 K Transcriptional regulator
NNMPHLEP_01917 3.5e-160
NNMPHLEP_01918 1.8e-34 1.6.5.5 C Zinc-binding dehydrogenase
NNMPHLEP_01919 1.3e-64 1.6.5.5 C Zinc-binding dehydrogenase
NNMPHLEP_01920 2.8e-23 1.6.5.5 C Zinc-binding dehydrogenase
NNMPHLEP_01921 1e-254 G PTS system Galactitol-specific IIC component
NNMPHLEP_01922 2.4e-212 EGP Major facilitator Superfamily
NNMPHLEP_01923 3e-135 V ABC transporter
NNMPHLEP_01924 9.7e-108
NNMPHLEP_01925 2.4e-14
NNMPHLEP_01926 7.1e-63
NNMPHLEP_01927 1.9e-194 lplA 6.3.1.20 H Lipoate-protein ligase
NNMPHLEP_01928 5.1e-81 uspA T universal stress protein
NNMPHLEP_01929 0.0 tetP J elongation factor G
NNMPHLEP_01930 3.4e-166 GK ROK family
NNMPHLEP_01931 7.4e-242 brnQ U Component of the transport system for branched-chain amino acids
NNMPHLEP_01932 7.8e-120 aroD S Serine hydrolase (FSH1)
NNMPHLEP_01933 1.1e-242 yagE E amino acid
NNMPHLEP_01934 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NNMPHLEP_01935 2.3e-133 gntR K UbiC transcription regulator-associated domain protein
NNMPHLEP_01936 4.6e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NNMPHLEP_01937 1.4e-283 pipD E Dipeptidase
NNMPHLEP_01938 0.0 yfiC V ABC transporter
NNMPHLEP_01939 2.4e-309 lmrA V ABC transporter, ATP-binding protein
NNMPHLEP_01940 1.4e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNMPHLEP_01941 2.1e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NNMPHLEP_01942 5.7e-137
NNMPHLEP_01943 2.6e-160 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NNMPHLEP_01944 1.8e-172 S AI-2E family transporter
NNMPHLEP_01945 4.7e-134 XK27_07210 6.1.1.6 S B3 4 domain
NNMPHLEP_01946 1.9e-77 yybA 2.3.1.57 K Transcriptional regulator
NNMPHLEP_01947 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
NNMPHLEP_01948 1.1e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
NNMPHLEP_01949 3.7e-154 ypdB V (ABC) transporter
NNMPHLEP_01950 1.5e-242 yhdP S Transporter associated domain
NNMPHLEP_01951 1.3e-84 nrdI F Belongs to the NrdI family
NNMPHLEP_01952 1.6e-73 S 3-demethylubiquinone-9 3-methyltransferase
NNMPHLEP_01953 1.7e-191 yeaN P Transporter, major facilitator family protein
NNMPHLEP_01954 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NNMPHLEP_01955 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NNMPHLEP_01956 3.9e-38
NNMPHLEP_01957 0.0 lacS G Transporter
NNMPHLEP_01958 1.5e-80 uspA T universal stress protein
NNMPHLEP_01959 2.5e-80 K AsnC family
NNMPHLEP_01960 4e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NNMPHLEP_01961 5.6e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
NNMPHLEP_01962 3.8e-179 galR K Transcriptional regulator
NNMPHLEP_01963 9e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NNMPHLEP_01964 2.9e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NNMPHLEP_01965 1e-176 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NNMPHLEP_01966 4.9e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
NNMPHLEP_01967 1.2e-91 yxkA S Phosphatidylethanolamine-binding protein
NNMPHLEP_01968 9.1e-36
NNMPHLEP_01969 5.9e-52
NNMPHLEP_01970 9e-201
NNMPHLEP_01971 3.7e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NNMPHLEP_01972 1.2e-135 pnuC H nicotinamide mononucleotide transporter
NNMPHLEP_01973 1.9e-155 ytbE 1.1.1.346 S Aldo keto reductase
NNMPHLEP_01974 1.4e-124 K response regulator
NNMPHLEP_01975 1.3e-179 T PhoQ Sensor
NNMPHLEP_01976 3.7e-134 macB2 V ABC transporter, ATP-binding protein
NNMPHLEP_01977 0.0 ysaB V FtsX-like permease family
NNMPHLEP_01978 2e-152 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NNMPHLEP_01979 7.7e-166 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NNMPHLEP_01980 1.4e-113 L Integrase core domain
NNMPHLEP_01981 1.6e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NNMPHLEP_01983 2.3e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNMPHLEP_01984 8.9e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NNMPHLEP_01985 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NNMPHLEP_01986 6.6e-35 ynzC S UPF0291 protein
NNMPHLEP_01987 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
NNMPHLEP_01988 4.6e-117 plsC 2.3.1.51 I Acyltransferase
NNMPHLEP_01989 3.2e-141 yabB 2.1.1.223 L Methyltransferase small domain
NNMPHLEP_01990 2.3e-47 yazA L GIY-YIG catalytic domain protein
NNMPHLEP_01991 3.7e-182 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NNMPHLEP_01992 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
NNMPHLEP_01993 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NNMPHLEP_01994 1.3e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NNMPHLEP_01995 3.7e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NNMPHLEP_01996 5.5e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NNMPHLEP_01997 1.7e-137 cdsA 2.7.7.41 I Belongs to the CDS family
NNMPHLEP_01998 8.3e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NNMPHLEP_01999 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NNMPHLEP_02000 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NNMPHLEP_02001 7.2e-60 L Belongs to the 'phage' integrase family
NNMPHLEP_02002 1.3e-12
NNMPHLEP_02003 3e-17 E Zn peptidase
NNMPHLEP_02004 1.8e-14 XK27_10050 K Peptidase S24-like
NNMPHLEP_02010 1.6e-32 S Siphovirus Gp157
NNMPHLEP_02011 5.3e-122 S AAA domain
NNMPHLEP_02012 6.2e-71
NNMPHLEP_02013 8.9e-255 L Helicase C-terminal domain protein
NNMPHLEP_02014 0.0 L Primase C terminal 2 (PriCT-2)
NNMPHLEP_02015 8.9e-42 rusA L Endodeoxyribonuclease RusA
NNMPHLEP_02016 4.2e-20
NNMPHLEP_02022 6.8e-07 xre K Transcriptional
NNMPHLEP_02026 3.1e-08
NNMPHLEP_02028 3.9e-144 ps334 S Terminase-like family
NNMPHLEP_02029 4.9e-140 S Phage portal protein
NNMPHLEP_02030 4.5e-103 K cell adhesion
NNMPHLEP_02033 1.7e-31 S aminoacyl-tRNA ligase activity
NNMPHLEP_02034 2.1e-96
NNMPHLEP_02035 2.2e-34 S Phage gp6-like head-tail connector protein
NNMPHLEP_02036 6.9e-12
NNMPHLEP_02037 9.3e-25 S Bacteriophage HK97-gp10, putative tail-component
NNMPHLEP_02038 8.8e-26 S Protein of unknown function (DUF3168)
NNMPHLEP_02039 1.1e-48 S Phage major tail protein 2
NNMPHLEP_02040 2.9e-28 S Pfam:Phage_TAC_12
NNMPHLEP_02041 5.3e-28
NNMPHLEP_02042 7.1e-70 D Phage tail tape measure protein, TP901 family
NNMPHLEP_02043 4e-78 S phage tail
NNMPHLEP_02044 2.4e-195 M Prophage endopeptidase tail
NNMPHLEP_02046 2.4e-36 E GDSL-like Lipase/Acylhydrolase
NNMPHLEP_02047 3.8e-57 S Bacteriophage holin family
NNMPHLEP_02048 5.5e-171 M hydrolase, family 25
NNMPHLEP_02050 1.2e-10 E Collagen triple helix repeat (20 copies)
NNMPHLEP_02052 5.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NNMPHLEP_02053 1.2e-214 nusA K Participates in both transcription termination and antitermination
NNMPHLEP_02054 1e-44 ylxR K Protein of unknown function (DUF448)
NNMPHLEP_02055 4.5e-49 ylxQ J ribosomal protein
NNMPHLEP_02056 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NNMPHLEP_02057 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NNMPHLEP_02058 4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NNMPHLEP_02059 6.5e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NNMPHLEP_02060 1e-63
NNMPHLEP_02061 1.2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NNMPHLEP_02062 4.6e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NNMPHLEP_02063 0.0 dnaK O Heat shock 70 kDa protein
NNMPHLEP_02064 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NNMPHLEP_02065 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NNMPHLEP_02066 1.1e-272 pipD E Dipeptidase
NNMPHLEP_02067 7.3e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NNMPHLEP_02068 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NNMPHLEP_02069 7.5e-58
NNMPHLEP_02070 1.7e-179 prmA J Ribosomal protein L11 methyltransferase
NNMPHLEP_02071 2.1e-126 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NNMPHLEP_02072 1e-51
NNMPHLEP_02073 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NNMPHLEP_02074 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NNMPHLEP_02076 2.1e-151 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NNMPHLEP_02077 5.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NNMPHLEP_02078 3.4e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NNMPHLEP_02079 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
NNMPHLEP_02080 8.9e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NNMPHLEP_02081 7e-93 lemA S LemA family
NNMPHLEP_02082 1.5e-158 htpX O Belongs to the peptidase M48B family
NNMPHLEP_02083 3.4e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NNMPHLEP_02084 1.5e-248 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NNMPHLEP_02085 0.0 sprD D Domain of Unknown Function (DUF1542)
NNMPHLEP_02086 2.9e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
NNMPHLEP_02087 6.8e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NNMPHLEP_02088 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNMPHLEP_02089 4.8e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
NNMPHLEP_02090 7.2e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NNMPHLEP_02092 3.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NNMPHLEP_02093 6.7e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NNMPHLEP_02094 4.2e-62 L Toxic component of a toxin-antitoxin (TA) module
NNMPHLEP_02095 4.4e-250 U Belongs to the purine-cytosine permease (2.A.39) family
NNMPHLEP_02096 3.7e-240 codA 3.5.4.1 F cytosine deaminase
NNMPHLEP_02097 2.9e-145 tesE Q hydratase
NNMPHLEP_02098 6.9e-113 S (CBS) domain
NNMPHLEP_02099 1.3e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NNMPHLEP_02100 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NNMPHLEP_02101 2.1e-39 yabO J S4 domain protein
NNMPHLEP_02102 3.3e-56 divIC D Septum formation initiator
NNMPHLEP_02103 9.8e-67 yabR J RNA binding
NNMPHLEP_02104 1.2e-253 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NNMPHLEP_02105 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NNMPHLEP_02106 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NNMPHLEP_02107 1.3e-168 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NNMPHLEP_02108 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NNMPHLEP_02109 3.3e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NNMPHLEP_02110 1.4e-52 entB 3.5.1.19 Q Isochorismatase family
NNMPHLEP_02111 2e-48 L PFAM transposase IS200-family protein
NNMPHLEP_02112 1.4e-64 XK27_06920 S Protein of unknown function (DUF1700)
NNMPHLEP_02113 2.3e-55 znuA P Belongs to the bacterial solute-binding protein 9 family
NNMPHLEP_02114 1e-151 K Transcriptional regulator, LysR family
NNMPHLEP_02115 3.8e-246 E Peptidase family M20/M25/M40
NNMPHLEP_02116 2.3e-218 G Transporter, major facilitator family protein
NNMPHLEP_02117 3.1e-206 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NNMPHLEP_02118 9.1e-298 L Transposase
NNMPHLEP_02119 1e-281 O Arylsulfotransferase (ASST)
NNMPHLEP_02120 3.6e-45 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NNMPHLEP_02123 7.1e-166 yniA G Phosphotransferase enzyme family
NNMPHLEP_02124 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NNMPHLEP_02125 1.4e-130 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NNMPHLEP_02126 1e-260 glnPH2 P ABC transporter permease
NNMPHLEP_02127 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NNMPHLEP_02128 3.8e-70 yqeY S YqeY-like protein
NNMPHLEP_02129 1.2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NNMPHLEP_02130 3.5e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NNMPHLEP_02131 1.8e-259 argH 4.3.2.1 E argininosuccinate lyase
NNMPHLEP_02132 4.8e-73 bioY S BioY family
NNMPHLEP_02133 3.9e-168 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NNMPHLEP_02134 9.9e-183 phoH T phosphate starvation-inducible protein PhoH
NNMPHLEP_02135 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NNMPHLEP_02136 1.9e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NNMPHLEP_02137 1.4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NNMPHLEP_02138 7.8e-143 recO L Involved in DNA repair and RecF pathway recombination
NNMPHLEP_02139 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NNMPHLEP_02140 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NNMPHLEP_02141 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NNMPHLEP_02142 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NNMPHLEP_02143 1.2e-219 patA 2.6.1.1 E Aminotransferase
NNMPHLEP_02144 1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
NNMPHLEP_02145 1.6e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NNMPHLEP_02146 6e-238 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NNMPHLEP_02147 3e-30 S Protein of unknown function (DUF2929)
NNMPHLEP_02148 0.0 dnaE 2.7.7.7 L DNA polymerase
NNMPHLEP_02149 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NNMPHLEP_02150 7.9e-168 cvfB S S1 domain
NNMPHLEP_02151 1.2e-163 xerD D recombinase XerD
NNMPHLEP_02152 4.3e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NNMPHLEP_02153 1.4e-139 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NNMPHLEP_02154 8.5e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NNMPHLEP_02155 9e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NNMPHLEP_02156 7.6e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NNMPHLEP_02157 6.1e-188 ypbB 5.1.3.1 S Helix-turn-helix domain
NNMPHLEP_02158 2.8e-263 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NNMPHLEP_02159 2.5e-13 M Lysin motif
NNMPHLEP_02160 7.9e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NNMPHLEP_02161 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NNMPHLEP_02162 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NNMPHLEP_02163 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NNMPHLEP_02164 2.8e-235 S Tetratricopeptide repeat protein
NNMPHLEP_02165 4.8e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NNMPHLEP_02166 0.0 yfmR S ABC transporter, ATP-binding protein
NNMPHLEP_02167 2.5e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NNMPHLEP_02168 9.3e-86 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NNMPHLEP_02169 5e-111 hlyIII S protein, hemolysin III
NNMPHLEP_02170 2.2e-151 DegV S EDD domain protein, DegV family
NNMPHLEP_02171 8.9e-170 ypmR E lipolytic protein G-D-S-L family
NNMPHLEP_02172 2.2e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NNMPHLEP_02173 4.4e-35 yozE S Belongs to the UPF0346 family
NNMPHLEP_02174 9.2e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NNMPHLEP_02175 9.4e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NNMPHLEP_02176 2.9e-162 dprA LU DNA protecting protein DprA
NNMPHLEP_02177 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NNMPHLEP_02178 1.6e-165 lacX 5.1.3.3 G Aldose 1-epimerase
NNMPHLEP_02179 9.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NNMPHLEP_02180 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNMPHLEP_02181 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NNMPHLEP_02182 3.5e-82 F NUDIX domain
NNMPHLEP_02183 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
NNMPHLEP_02184 4.1e-68 yqkB S Belongs to the HesB IscA family
NNMPHLEP_02185 4.2e-50
NNMPHLEP_02187 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NNMPHLEP_02188 8.2e-61 asp S Asp23 family, cell envelope-related function
NNMPHLEP_02189 2.1e-25
NNMPHLEP_02190 1.4e-95
NNMPHLEP_02191 1.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NNMPHLEP_02192 8.1e-39 K Transcriptional regulator, LacI family
NNMPHLEP_02193 8.7e-122 K Transcriptional regulator, LacI family
NNMPHLEP_02194 1.1e-229 gntT EG Gluconate
NNMPHLEP_02195 1.2e-91 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NNMPHLEP_02196 3.1e-136 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NNMPHLEP_02197 3.2e-95 K Acetyltransferase (GNAT) domain
NNMPHLEP_02198 9.3e-47
NNMPHLEP_02199 2.4e-22
NNMPHLEP_02200 2.2e-44
NNMPHLEP_02201 8e-53 yhaI S Protein of unknown function (DUF805)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)