ORF_ID e_value Gene_name EC_number CAZy COGs Description
IPKOFKLA_00001 8.3e-31 L PFAM Integrase catalytic region
IPKOFKLA_00003 5.5e-232 S Putative peptidoglycan binding domain
IPKOFKLA_00004 5.3e-52 M NlpC P60 family protein
IPKOFKLA_00005 1.2e-35
IPKOFKLA_00007 3e-213 bacI V MacB-like periplasmic core domain
IPKOFKLA_00008 9.8e-129 V ABC transporter
IPKOFKLA_00009 4.4e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IPKOFKLA_00010 5.2e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IPKOFKLA_00011 7.8e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPKOFKLA_00012 9.4e-149 E Glyoxalase-like domain
IPKOFKLA_00013 7.5e-155 glcU U sugar transport
IPKOFKLA_00014 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
IPKOFKLA_00015 2.2e-96 S reductase
IPKOFKLA_00016 1.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IPKOFKLA_00017 2.7e-17 ABC-SBP S ABC transporter
IPKOFKLA_00018 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IPKOFKLA_00019 1.9e-218 htrA 3.4.21.107 O serine protease
IPKOFKLA_00020 2.3e-153 vicX 3.1.26.11 S domain protein
IPKOFKLA_00021 5.4e-150 yycI S YycH protein
IPKOFKLA_00022 1.5e-247 yycH S YycH protein
IPKOFKLA_00023 0.0 vicK 2.7.13.3 T Histidine kinase
IPKOFKLA_00024 5.2e-130 K response regulator
IPKOFKLA_00026 3.4e-308 lmrA 3.6.3.44 V ABC transporter
IPKOFKLA_00027 2.3e-72 K helix_turn_helix multiple antibiotic resistance protein
IPKOFKLA_00029 5.7e-122 Z012_01130 S Fic/DOC family
IPKOFKLA_00030 1.1e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
IPKOFKLA_00031 4.8e-54
IPKOFKLA_00032 2.2e-205 yttB EGP Major facilitator Superfamily
IPKOFKLA_00033 6.9e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IPKOFKLA_00034 7.6e-74 rplI J Binds to the 23S rRNA
IPKOFKLA_00035 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IPKOFKLA_00036 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPKOFKLA_00037 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IPKOFKLA_00038 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
IPKOFKLA_00039 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPKOFKLA_00040 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPKOFKLA_00041 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPKOFKLA_00042 6.4e-34 yaaA S S4 domain protein YaaA
IPKOFKLA_00043 2.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IPKOFKLA_00044 1.9e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPKOFKLA_00045 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IPKOFKLA_00046 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IPKOFKLA_00047 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPKOFKLA_00048 9.7e-130 jag S R3H domain protein
IPKOFKLA_00049 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPKOFKLA_00050 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IPKOFKLA_00051 0.0 asnB 6.3.5.4 E Asparagine synthase
IPKOFKLA_00052 2.4e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPKOFKLA_00053 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
IPKOFKLA_00054 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IPKOFKLA_00055 1.6e-88 2.3.1.183 M Acetyltransferase GNAT family
IPKOFKLA_00056 2.3e-159 S reductase
IPKOFKLA_00058 1.9e-07 yiiE S Psort location CytoplasmicMembrane, score 10.00
IPKOFKLA_00060 7.5e-57 K LysR substrate binding domain
IPKOFKLA_00061 7.7e-299 S amidohydrolase
IPKOFKLA_00063 4e-36 blpT
IPKOFKLA_00064 6.5e-45 K LytTr DNA-binding domain
IPKOFKLA_00065 1.9e-24 plnB 2.7.13.3 T GHKL domain
IPKOFKLA_00067 1.6e-105 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IPKOFKLA_00068 5.9e-205 3.6.4.12 L DNA helicase
IPKOFKLA_00069 3e-306 S AAA domain, putative AbiEii toxin, Type IV TA system
IPKOFKLA_00070 1.1e-42 S Uncharacterised protein family (UPF0236)
IPKOFKLA_00072 6e-08
IPKOFKLA_00073 2.8e-154 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IPKOFKLA_00074 8.3e-221 L PFAM Integrase catalytic region
IPKOFKLA_00075 3.1e-33 L PFAM Integrase catalytic region
IPKOFKLA_00076 2.8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
IPKOFKLA_00077 3.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IPKOFKLA_00078 1.5e-112 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IPKOFKLA_00079 1.7e-249 yagE E amino acid
IPKOFKLA_00080 2.9e-84 dps P Belongs to the Dps family
IPKOFKLA_00081 0.0 pacL 3.6.3.8 P P-type ATPase
IPKOFKLA_00082 3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IPKOFKLA_00083 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IPKOFKLA_00084 2.2e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IPKOFKLA_00085 4.5e-146 potB P ABC transporter permease
IPKOFKLA_00086 7.1e-139 potC P ABC transporter permease
IPKOFKLA_00087 2.5e-208 potD P ABC transporter
IPKOFKLA_00088 1.3e-230
IPKOFKLA_00089 1.1e-234 EGP Sugar (and other) transporter
IPKOFKLA_00090 1.3e-254 yfnA E Amino Acid
IPKOFKLA_00091 2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IPKOFKLA_00092 3.2e-98 gmk2 2.7.4.8 F Guanylate kinase
IPKOFKLA_00093 1.5e-82 zur P Belongs to the Fur family
IPKOFKLA_00094 3.1e-17 3.2.1.14 GH18
IPKOFKLA_00095 5.4e-150
IPKOFKLA_00096 8.3e-38 pspC KT PspC domain protein
IPKOFKLA_00097 1.6e-94 K Transcriptional regulator (TetR family)
IPKOFKLA_00098 1.9e-234 V domain protein
IPKOFKLA_00099 5.1e-179 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPKOFKLA_00101 6.6e-35 S Transglycosylase associated protein
IPKOFKLA_00102 1.6e-233 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPKOFKLA_00103 1.9e-126 G phosphoglycerate mutase
IPKOFKLA_00104 1.2e-115 dedA S SNARE associated Golgi protein
IPKOFKLA_00105 0.0 helD 3.6.4.12 L DNA helicase
IPKOFKLA_00106 7.9e-244 nox C NADH oxidase
IPKOFKLA_00107 2.9e-254 nox C NADH oxidase
IPKOFKLA_00108 2.5e-158 EG EamA-like transporter family
IPKOFKLA_00109 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IPKOFKLA_00110 1.3e-176 coaA 2.7.1.33 F Pantothenic acid kinase
IPKOFKLA_00111 3e-223 S cog cog1373
IPKOFKLA_00113 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IPKOFKLA_00115 6.8e-45 2.1.1.72 L Type III restriction/modification enzyme methylation subunit
IPKOFKLA_00116 6.7e-104 sthIM 2.1.1.72 L DNA methylase
IPKOFKLA_00117 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
IPKOFKLA_00118 1.1e-218 oxlT P Major Facilitator Superfamily
IPKOFKLA_00119 6.2e-157 spoU 2.1.1.185 J Methyltransferase
IPKOFKLA_00120 2.1e-37 rmeB K transcriptional regulator, MerR family
IPKOFKLA_00121 7.2e-08 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IPKOFKLA_00122 9.8e-27 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IPKOFKLA_00123 1.5e-99 crp_2 K Cyclic nucleotide-binding domain
IPKOFKLA_00124 3.3e-127 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
IPKOFKLA_00125 1.2e-137 pnuC H nicotinamide mononucleotide transporter
IPKOFKLA_00126 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IPKOFKLA_00127 8.8e-99 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IPKOFKLA_00128 2.5e-44 L Helix-turn-helix domain
IPKOFKLA_00129 1.1e-62 L Helix-turn-helix domain
IPKOFKLA_00130 7.6e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPKOFKLA_00131 3.1e-163
IPKOFKLA_00132 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IPKOFKLA_00133 2.6e-241 purD 6.3.4.13 F Belongs to the GARS family
IPKOFKLA_00134 1.6e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IPKOFKLA_00135 1.2e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IPKOFKLA_00136 1.1e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IPKOFKLA_00137 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IPKOFKLA_00138 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPKOFKLA_00139 4.4e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPKOFKLA_00140 2.6e-36 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPKOFKLA_00141 5.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IPKOFKLA_00142 3.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IPKOFKLA_00143 3.7e-218 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IPKOFKLA_00144 7.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IPKOFKLA_00145 3.6e-126 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IPKOFKLA_00146 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IPKOFKLA_00147 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IPKOFKLA_00148 1.1e-176 K AI-2E family transporter
IPKOFKLA_00149 1.4e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IPKOFKLA_00150 3.7e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
IPKOFKLA_00151 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPKOFKLA_00152 2.7e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IPKOFKLA_00153 1.9e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IPKOFKLA_00154 6.9e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IPKOFKLA_00155 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IPKOFKLA_00156 7.4e-134 K LysR substrate binding domain
IPKOFKLA_00157 5.6e-53 azlD S branched-chain amino acid
IPKOFKLA_00158 3.2e-140 azlC E AzlC protein
IPKOFKLA_00159 1.4e-201 hpk31 2.7.13.3 T Histidine kinase
IPKOFKLA_00160 3.8e-125 K response regulator
IPKOFKLA_00161 7.7e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IPKOFKLA_00162 2.8e-171 deoR K sugar-binding domain protein
IPKOFKLA_00163 3.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IPKOFKLA_00164 4.5e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
IPKOFKLA_00165 3.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IPKOFKLA_00166 2.8e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IPKOFKLA_00167 5.9e-135 XK27_01040 S Protein of unknown function (DUF1129)
IPKOFKLA_00168 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IPKOFKLA_00169 9.1e-32 yyzM S Bacterial protein of unknown function (DUF951)
IPKOFKLA_00170 6.5e-154 spo0J K Belongs to the ParB family
IPKOFKLA_00171 3.9e-139 soj D Sporulation initiation inhibitor
IPKOFKLA_00172 9.6e-151 noc K Belongs to the ParB family
IPKOFKLA_00173 2.3e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IPKOFKLA_00174 8.5e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
IPKOFKLA_00175 2.5e-169 rihC 3.2.2.1 F Nucleoside
IPKOFKLA_00176 1.3e-218 nupG F Nucleoside transporter
IPKOFKLA_00177 2.7e-220 cycA E Amino acid permease
IPKOFKLA_00179 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPKOFKLA_00180 3e-265 glnP P ABC transporter
IPKOFKLA_00181 8.5e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPKOFKLA_00182 0.0 infB UW LPXTG-motif cell wall anchor domain protein
IPKOFKLA_00183 3.4e-81 S ECF transporter, substrate-specific component
IPKOFKLA_00184 9.6e-62 S Domain of unknown function (DUF4430)
IPKOFKLA_00185 2.2e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
IPKOFKLA_00186 5.3e-130 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IPKOFKLA_00187 7e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
IPKOFKLA_00188 9.9e-135 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IPKOFKLA_00189 7.8e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
IPKOFKLA_00190 1.4e-250 hemL 5.4.3.8 H Aminotransferase class-III
IPKOFKLA_00191 3.8e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
IPKOFKLA_00192 2.9e-165 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IPKOFKLA_00193 4.4e-228 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IPKOFKLA_00194 6.7e-78 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
IPKOFKLA_00195 1.8e-276 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
IPKOFKLA_00196 2.8e-148 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
IPKOFKLA_00197 4.4e-118 cbiQ P Cobalt transport protein
IPKOFKLA_00198 8.7e-53 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IPKOFKLA_00199 5.3e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
IPKOFKLA_00200 2.1e-123 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IPKOFKLA_00201 1.8e-144 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
IPKOFKLA_00202 3.4e-258 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IPKOFKLA_00203 6.4e-134 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
IPKOFKLA_00204 1.8e-130 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IPKOFKLA_00205 5.5e-192 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
IPKOFKLA_00206 1.2e-132 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IPKOFKLA_00207 1.7e-96 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
IPKOFKLA_00208 9.7e-109 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
IPKOFKLA_00209 1.5e-206 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
IPKOFKLA_00210 2.7e-123 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
IPKOFKLA_00211 1.7e-179 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IPKOFKLA_00212 1.5e-261 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
IPKOFKLA_00213 3.7e-207 cobD 4.1.1.81 E Aminotransferase class I and II
IPKOFKLA_00214 6.3e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
IPKOFKLA_00215 7.3e-155 XK27_04590 S NADPH-dependent FMN reductase
IPKOFKLA_00216 3.9e-78 fld C Flavodoxin
IPKOFKLA_00217 8.8e-72 eutP E Ethanolamine utilisation - propanediol utilisation
IPKOFKLA_00218 6.7e-80 P Cadmium resistance transporter
IPKOFKLA_00219 1.3e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
IPKOFKLA_00220 1.4e-147 3.1.3.48 T Pfam:Y_phosphatase3C
IPKOFKLA_00221 5.5e-56 pduU E BMC
IPKOFKLA_00222 1.4e-220 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPKOFKLA_00223 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
IPKOFKLA_00224 3.1e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
IPKOFKLA_00225 7.4e-80 pduO S Haem-degrading
IPKOFKLA_00226 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
IPKOFKLA_00227 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
IPKOFKLA_00228 6.4e-90 S Putative propanediol utilisation
IPKOFKLA_00229 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
IPKOFKLA_00230 4.9e-42 pduA_4 CQ BMC
IPKOFKLA_00231 1.4e-72 pduK CQ BMC
IPKOFKLA_00232 2.5e-59 pduH S Dehydratase medium subunit
IPKOFKLA_00233 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
IPKOFKLA_00234 3.7e-77 pduE 4.2.1.28 Q Dehydratase small subunit
IPKOFKLA_00235 4.2e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
IPKOFKLA_00236 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
IPKOFKLA_00237 2.7e-134 pduB E BMC
IPKOFKLA_00238 6.2e-42 pduA_4 CQ BMC
IPKOFKLA_00239 3.4e-197 K helix_turn_helix, arabinose operon control protein
IPKOFKLA_00240 7.8e-149 eutJ E Hsp70 protein
IPKOFKLA_00241 1.2e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IPKOFKLA_00242 2.1e-163
IPKOFKLA_00243 2.4e-158 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IPKOFKLA_00244 8.7e-172 S AI-2E family transporter
IPKOFKLA_00245 8.9e-133 XK27_07210 6.1.1.6 S B3 4 domain
IPKOFKLA_00246 2.5e-77 yybA 2.3.1.57 K Transcriptional regulator
IPKOFKLA_00247 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
IPKOFKLA_00248 1.8e-90 GM epimerase
IPKOFKLA_00249 6.3e-154 ypdB V (ABC) transporter
IPKOFKLA_00250 1.6e-241 yhdP S Transporter associated domain
IPKOFKLA_00251 1.3e-84 nrdI F Belongs to the NrdI family
IPKOFKLA_00252 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
IPKOFKLA_00253 9.8e-192 yeaN P Transporter, major facilitator family protein
IPKOFKLA_00254 2.9e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IPKOFKLA_00255 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IPKOFKLA_00256 2e-33
IPKOFKLA_00257 0.0 lacS G Transporter
IPKOFKLA_00258 2.4e-248 fucP G Major Facilitator Superfamily
IPKOFKLA_00259 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IPKOFKLA_00260 3.8e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPKOFKLA_00261 4.7e-168 murB 1.3.1.98 M Cell wall formation
IPKOFKLA_00262 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
IPKOFKLA_00263 3.8e-75 S PAS domain
IPKOFKLA_00264 3e-87 K Acetyltransferase (GNAT) domain
IPKOFKLA_00265 6.5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IPKOFKLA_00266 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IPKOFKLA_00267 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPKOFKLA_00268 2.6e-103 yxjI
IPKOFKLA_00269 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IPKOFKLA_00270 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IPKOFKLA_00271 2.8e-145 est 3.1.1.1 S Serine aminopeptidase, S33
IPKOFKLA_00272 1.8e-34 secG U Preprotein translocase
IPKOFKLA_00273 6.9e-292 clcA P chloride
IPKOFKLA_00274 1.2e-247 yifK E Amino acid permease
IPKOFKLA_00275 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IPKOFKLA_00276 6.3e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IPKOFKLA_00277 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IPKOFKLA_00278 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IPKOFKLA_00280 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IPKOFKLA_00281 3.7e-241 glpT G Major Facilitator Superfamily
IPKOFKLA_00282 8.8e-15
IPKOFKLA_00284 3.1e-170 whiA K May be required for sporulation
IPKOFKLA_00285 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IPKOFKLA_00286 1.7e-162 rapZ S Displays ATPase and GTPase activities
IPKOFKLA_00287 1.1e-245 steT E amino acid
IPKOFKLA_00288 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IPKOFKLA_00289 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IPKOFKLA_00290 6.9e-14
IPKOFKLA_00291 5.1e-116 yfbR S HD containing hydrolase-like enzyme
IPKOFKLA_00292 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IPKOFKLA_00293 3.9e-87 ykhA 3.1.2.20 I Thioesterase superfamily
IPKOFKLA_00294 5.9e-163 aatB ET PFAM extracellular solute-binding protein, family 3
IPKOFKLA_00295 6.9e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IPKOFKLA_00296 3.9e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IPKOFKLA_00297 5.6e-166 lutA C Cysteine-rich domain
IPKOFKLA_00298 9.8e-288 lutB C 4Fe-4S dicluster domain
IPKOFKLA_00299 2.8e-134 yrjD S LUD domain
IPKOFKLA_00300 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IPKOFKLA_00301 5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IPKOFKLA_00302 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IPKOFKLA_00303 6.6e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IPKOFKLA_00304 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IPKOFKLA_00305 5.9e-31 KT PspC domain protein
IPKOFKLA_00306 7.8e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPKOFKLA_00307 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IPKOFKLA_00308 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPKOFKLA_00309 7.5e-126 comFC S Competence protein
IPKOFKLA_00310 4.1e-253 comFA L Helicase C-terminal domain protein
IPKOFKLA_00311 5.7e-140 L PFAM transposase IS116 IS110 IS902
IPKOFKLA_00312 9.8e-112 yvyE 3.4.13.9 S YigZ family
IPKOFKLA_00313 4.3e-95
IPKOFKLA_00314 2.3e-52 S COG0463 Glycosyltransferases involved in cell wall biogenesis
IPKOFKLA_00315 1.1e-87 GT4 G Glycosyl transferase 4-like
IPKOFKLA_00316 1.7e-50 pglC M Bacterial sugar transferase
IPKOFKLA_00317 3e-120 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IPKOFKLA_00318 2.7e-144 epsB M biosynthesis protein
IPKOFKLA_00319 1.5e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IPKOFKLA_00320 2.2e-69 K Transcriptional regulator, HxlR family
IPKOFKLA_00321 8.5e-128
IPKOFKLA_00322 1.3e-102 K DNA-templated transcription, initiation
IPKOFKLA_00323 3.6e-35
IPKOFKLA_00324 1.9e-81
IPKOFKLA_00325 6.2e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPKOFKLA_00326 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IPKOFKLA_00327 0.0 yjbQ P TrkA C-terminal domain protein
IPKOFKLA_00328 1.9e-272 pipD E Dipeptidase
IPKOFKLA_00332 3.9e-287 GT2,GT4 M family 8
IPKOFKLA_00333 3.2e-305 M family 8
IPKOFKLA_00335 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IPKOFKLA_00336 1.7e-290 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IPKOFKLA_00337 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IPKOFKLA_00338 1.8e-164 asp3 S Accessory Sec secretory system ASP3
IPKOFKLA_00339 4.1e-286 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
IPKOFKLA_00340 3.8e-287 M transferase activity, transferring glycosyl groups
IPKOFKLA_00341 2.5e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
IPKOFKLA_00342 4.2e-39 cpsJ S glycosyl transferase family 2
IPKOFKLA_00343 5.5e-30 cpsJ S glycosyl transferase family 2
IPKOFKLA_00344 9.2e-189 nss M transferase activity, transferring glycosyl groups
IPKOFKLA_00345 0.0 M LPXTG-motif cell wall anchor domain protein
IPKOFKLA_00346 0.0 trxB2 1.8.1.9 C Thioredoxin domain
IPKOFKLA_00347 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
IPKOFKLA_00348 7.2e-137 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IPKOFKLA_00349 1.4e-116 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IPKOFKLA_00351 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPKOFKLA_00352 2.7e-165 T Calcineurin-like phosphoesterase superfamily domain
IPKOFKLA_00353 8.2e-224 mdtG EGP Major facilitator Superfamily
IPKOFKLA_00354 2.3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IPKOFKLA_00355 1.6e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
IPKOFKLA_00356 1.3e-142 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
IPKOFKLA_00357 2.6e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IPKOFKLA_00358 1.5e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IPKOFKLA_00359 6.7e-40 L PFAM Integrase catalytic region
IPKOFKLA_00360 2.6e-237 lmrB EGP Major facilitator Superfamily
IPKOFKLA_00361 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IPKOFKLA_00362 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IPKOFKLA_00363 1.5e-109 sufD O Uncharacterized protein family (UPF0051)
IPKOFKLA_00364 6.7e-81 lytE M LysM domain protein
IPKOFKLA_00365 0.0 oppD EP Psort location Cytoplasmic, score
IPKOFKLA_00366 3.3e-92 lytE M LysM domain protein
IPKOFKLA_00367 9.2e-149 xth 3.1.11.2 L exodeoxyribonuclease III
IPKOFKLA_00368 2.1e-114 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
IPKOFKLA_00369 1.7e-142 preA 1.3.1.1 C 4Fe-4S dicluster domain
IPKOFKLA_00370 1.3e-151 yeaE S Aldo keto
IPKOFKLA_00371 7e-77 hsp O Belongs to the small heat shock protein (HSP20) family
IPKOFKLA_00372 4e-281 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
IPKOFKLA_00373 4.5e-79 S Psort location Cytoplasmic, score
IPKOFKLA_00374 2.9e-85 S Short repeat of unknown function (DUF308)
IPKOFKLA_00375 1e-23
IPKOFKLA_00376 2.8e-102 V VanZ like family
IPKOFKLA_00377 1.5e-231 cycA E Amino acid permease
IPKOFKLA_00378 1.6e-84 perR P Belongs to the Fur family
IPKOFKLA_00379 6.7e-257 EGP Major facilitator Superfamily
IPKOFKLA_00380 1.3e-93 tag 3.2.2.20 L glycosylase
IPKOFKLA_00381 4.3e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IPKOFKLA_00382 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IPKOFKLA_00383 4.5e-42
IPKOFKLA_00384 1e-301 ytgP S Polysaccharide biosynthesis protein
IPKOFKLA_00385 1.7e-28
IPKOFKLA_00386 5.2e-29
IPKOFKLA_00388 2e-18 K Cro/C1-type HTH DNA-binding domain
IPKOFKLA_00389 7.5e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IPKOFKLA_00390 2.5e-277 pepV 3.5.1.18 E dipeptidase PepV
IPKOFKLA_00391 4.3e-86 uspA T Belongs to the universal stress protein A family
IPKOFKLA_00392 9.2e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IPKOFKLA_00393 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
IPKOFKLA_00394 1.5e-112
IPKOFKLA_00395 2.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
IPKOFKLA_00396 2e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPKOFKLA_00397 2.1e-32
IPKOFKLA_00398 7.5e-118 S CAAX protease self-immunity
IPKOFKLA_00399 1.9e-43
IPKOFKLA_00401 1.9e-54
IPKOFKLA_00402 2.1e-143 S Domain of unknown function DUF1829
IPKOFKLA_00403 1.5e-73
IPKOFKLA_00404 1.1e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IPKOFKLA_00405 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IPKOFKLA_00406 1.2e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
IPKOFKLA_00407 2.1e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IPKOFKLA_00408 1.8e-102 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
IPKOFKLA_00409 3.1e-212 folP 2.5.1.15 H dihydropteroate synthase
IPKOFKLA_00410 3e-43
IPKOFKLA_00411 3.3e-40
IPKOFKLA_00413 5.4e-78 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IPKOFKLA_00414 5.4e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IPKOFKLA_00415 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPKOFKLA_00416 1.7e-207 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IPKOFKLA_00417 3.1e-245 M Glycosyl transferase family group 2
IPKOFKLA_00419 2.1e-224 aadAT EK Aminotransferase, class I
IPKOFKLA_00420 1.5e-31 S Predicted membrane protein (DUF2207)
IPKOFKLA_00421 6.7e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IPKOFKLA_00422 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPKOFKLA_00423 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
IPKOFKLA_00424 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IPKOFKLA_00425 1e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPKOFKLA_00426 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IPKOFKLA_00427 3.8e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IPKOFKLA_00428 2.3e-207 yacL S domain protein
IPKOFKLA_00429 2.5e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IPKOFKLA_00430 3.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IPKOFKLA_00431 7.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
IPKOFKLA_00432 7.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IPKOFKLA_00433 9.5e-266 pepC 3.4.22.40 E Peptidase C1-like family
IPKOFKLA_00434 4.3e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IPKOFKLA_00435 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPKOFKLA_00436 1.1e-119 tcyB E ABC transporter
IPKOFKLA_00437 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IPKOFKLA_00438 1.1e-169 I alpha/beta hydrolase fold
IPKOFKLA_00439 6e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IPKOFKLA_00440 0.0 S Bacterial membrane protein, YfhO
IPKOFKLA_00441 2.5e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IPKOFKLA_00442 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IPKOFKLA_00444 2.8e-84 ydcK S Belongs to the SprT family
IPKOFKLA_00445 0.0 yhgF K Tex-like protein N-terminal domain protein
IPKOFKLA_00446 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IPKOFKLA_00447 5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IPKOFKLA_00448 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
IPKOFKLA_00449 1.1e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IPKOFKLA_00450 1.2e-302 aspT P Predicted Permease Membrane Region
IPKOFKLA_00451 2.2e-249 EGP Major facilitator Superfamily
IPKOFKLA_00452 1e-111
IPKOFKLA_00455 1.8e-50 yjjH S Calcineurin-like phosphoesterase
IPKOFKLA_00456 4.2e-89 yjjH S Calcineurin-like phosphoesterase
IPKOFKLA_00457 1.3e-263 dtpT U amino acid peptide transporter
IPKOFKLA_00458 2.4e-18
IPKOFKLA_00460 1.7e-168 yqiG C Oxidoreductase
IPKOFKLA_00461 4.1e-62 S macrophage migration inhibitory factor
IPKOFKLA_00462 1.8e-65 K HxlR-like helix-turn-helix
IPKOFKLA_00463 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IPKOFKLA_00464 1.4e-58
IPKOFKLA_00465 1.3e-224 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IPKOFKLA_00467 1.7e-111 lssY 3.6.1.27 I Acid phosphatase homologues
IPKOFKLA_00468 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IPKOFKLA_00469 1.7e-227 clcA_2 P Chloride transporter, ClC family
IPKOFKLA_00470 8.5e-119 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IPKOFKLA_00471 1.8e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IPKOFKLA_00472 6.2e-64 L Belongs to the 'phage' integrase family
IPKOFKLA_00476 1.1e-10
IPKOFKLA_00477 3.5e-20 E Zn peptidase
IPKOFKLA_00478 8.9e-50 ps115 K Helix-turn-helix XRE-family like proteins
IPKOFKLA_00479 2.6e-13
IPKOFKLA_00487 4e-162 recT L RecT family
IPKOFKLA_00488 1.9e-149 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
IPKOFKLA_00489 7.3e-47 ybl78 L Conserved phage C-terminus (Phg_2220_C)
IPKOFKLA_00490 5.1e-27
IPKOFKLA_00494 4e-16
IPKOFKLA_00495 1e-54 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
IPKOFKLA_00497 2.3e-81 Q DNA (cytosine-5-)-methyltransferase activity
IPKOFKLA_00498 3.9e-22
IPKOFKLA_00501 2.6e-16
IPKOFKLA_00504 1.4e-83 arpU S Phage transcriptional regulator, ArpU family
IPKOFKLA_00505 7.2e-121 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
IPKOFKLA_00506 1.4e-66
IPKOFKLA_00508 1.5e-109 K Belongs to the N(4) N(6)-methyltransferase family
IPKOFKLA_00510 2.2e-259 S Phage terminase, large subunit
IPKOFKLA_00511 3.5e-310 S Phage portal protein, SPP1 Gp6-like
IPKOFKLA_00512 4.2e-167 S Phage Mu protein F like protein
IPKOFKLA_00514 2.1e-96 S Domain of unknown function (DUF4355)
IPKOFKLA_00515 5.2e-198 gpG
IPKOFKLA_00516 1.3e-60 S Phage gp6-like head-tail connector protein
IPKOFKLA_00517 7.9e-46
IPKOFKLA_00518 1.8e-77
IPKOFKLA_00519 1.2e-70
IPKOFKLA_00520 9.1e-121
IPKOFKLA_00521 1.5e-92 S Phage tail assembly chaperone protein, TAC
IPKOFKLA_00522 1.2e-240 D NLP P60 protein
IPKOFKLA_00523 1.2e-168 S Phage tail protein
IPKOFKLA_00524 0.0 M CHAP domain
IPKOFKLA_00527 1.1e-49 S Calcineurin-like phosphoesterase
IPKOFKLA_00530 4.4e-55 S Bacteriophage holin family
IPKOFKLA_00531 2.3e-73 S Bacteriophage holin of superfamily 6 (Holin_LLH)
IPKOFKLA_00532 1.1e-151 M Glycosyl hydrolases family 25
IPKOFKLA_00533 4.1e-13
IPKOFKLA_00534 1.1e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IPKOFKLA_00535 1.6e-193 M transferase activity, transferring glycosyl groups
IPKOFKLA_00536 9.3e-200 waaB GT4 M Glycosyl transferases group 1
IPKOFKLA_00537 8.3e-260 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
IPKOFKLA_00538 1.4e-105 M biosynthesis protein
IPKOFKLA_00539 1.6e-216 cps3F
IPKOFKLA_00540 3.9e-220 glf 5.4.99.9 M UDP-galactopyranose mutase
IPKOFKLA_00541 5.1e-116 rfbP 2.7.8.6 M Bacterial sugar transferase
IPKOFKLA_00542 8e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IPKOFKLA_00543 6.7e-147 cps1D M Domain of unknown function (DUF4422)
IPKOFKLA_00544 7.4e-141 recX 2.4.1.337 GT4 S Regulatory protein RecX
IPKOFKLA_00545 1.9e-30
IPKOFKLA_00546 1.9e-33 S Protein of unknown function (DUF2922)
IPKOFKLA_00547 1.5e-153 yihY S Belongs to the UPF0761 family
IPKOFKLA_00548 2e-280 yjeM E Amino Acid
IPKOFKLA_00549 2.5e-256 E Arginine ornithine antiporter
IPKOFKLA_00550 1.3e-220 arcT 2.6.1.1 E Aminotransferase
IPKOFKLA_00551 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
IPKOFKLA_00552 3.9e-78 fld C Flavodoxin
IPKOFKLA_00553 2.3e-67 gtcA S Teichoic acid glycosylation protein
IPKOFKLA_00554 2.1e-55
IPKOFKLA_00555 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IPKOFKLA_00557 2.5e-231 yfmL L DEAD DEAH box helicase
IPKOFKLA_00558 1.3e-190 mocA S Oxidoreductase
IPKOFKLA_00559 9.1e-62 S Domain of unknown function (DUF4828)
IPKOFKLA_00560 2e-103 yvdD 3.2.2.10 S Belongs to the LOG family
IPKOFKLA_00561 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IPKOFKLA_00562 2.1e-293 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IPKOFKLA_00563 1.7e-190 S Protein of unknown function (DUF3114)
IPKOFKLA_00564 5e-73 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
IPKOFKLA_00565 5.4e-119 ybhL S Belongs to the BI1 family
IPKOFKLA_00566 5.5e-21
IPKOFKLA_00567 5.2e-72 K LytTr DNA-binding domain
IPKOFKLA_00568 1.2e-68 S Protein of unknown function (DUF3021)
IPKOFKLA_00569 8.4e-136 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
IPKOFKLA_00570 1.5e-22 XK27_00915 C Luciferase-like monooxygenase
IPKOFKLA_00571 5.4e-121 pnb C nitroreductase
IPKOFKLA_00572 2.9e-88
IPKOFKLA_00573 2.3e-243 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
IPKOFKLA_00574 1.1e-38 amtB P ammonium transporter
IPKOFKLA_00575 7.6e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IPKOFKLA_00577 1.1e-47
IPKOFKLA_00578 1.1e-153 cylA V ABC transporter
IPKOFKLA_00579 4.5e-144 cylB V ABC-2 type transporter
IPKOFKLA_00580 7.6e-74 K LytTr DNA-binding domain
IPKOFKLA_00581 1.8e-60 S Protein of unknown function (DUF3021)
IPKOFKLA_00583 2.2e-176 L Plasmid pRiA4b ORF-3-like protein
IPKOFKLA_00584 2e-71 1.6.5.2 S NADPH-dependent FMN reductase
IPKOFKLA_00585 1.3e-85 K Bacterial regulatory proteins, tetR family
IPKOFKLA_00586 1.2e-48 entB 3.5.1.19 Q Isochorismatase family
IPKOFKLA_00588 1.4e-292 L Transposase IS66 family
IPKOFKLA_00589 9.2e-52 XK27_01125 L PFAM IS66 Orf2 family protein
IPKOFKLA_00591 7.8e-183 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IPKOFKLA_00592 2.9e-159 rrmA 2.1.1.187 H Methyltransferase
IPKOFKLA_00593 5.7e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IPKOFKLA_00594 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IPKOFKLA_00595 1.2e-10 S Protein of unknown function (DUF4044)
IPKOFKLA_00596 5e-57
IPKOFKLA_00597 1.5e-76 mraZ K Belongs to the MraZ family
IPKOFKLA_00598 3.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IPKOFKLA_00599 1.5e-56 ftsL D Cell division protein FtsL
IPKOFKLA_00600 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IPKOFKLA_00601 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPKOFKLA_00602 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPKOFKLA_00603 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPKOFKLA_00604 5.1e-140 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IPKOFKLA_00605 1.2e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IPKOFKLA_00606 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IPKOFKLA_00607 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IPKOFKLA_00608 3.2e-40 yggT S YGGT family
IPKOFKLA_00609 1.2e-140 ylmH S S4 domain protein
IPKOFKLA_00610 1.9e-42 divIVA D DivIVA domain protein
IPKOFKLA_00611 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPKOFKLA_00612 4.2e-32 cspA K Cold shock protein
IPKOFKLA_00613 3.2e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IPKOFKLA_00615 1.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IPKOFKLA_00616 2.1e-216 iscS 2.8.1.7 E Aminotransferase class V
IPKOFKLA_00617 2.8e-57 XK27_04120 S Putative amino acid metabolism
IPKOFKLA_00618 3.4e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IPKOFKLA_00619 8.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IPKOFKLA_00620 9e-119 S Repeat protein
IPKOFKLA_00621 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IPKOFKLA_00622 1.2e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPKOFKLA_00623 8.6e-187 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IPKOFKLA_00624 1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
IPKOFKLA_00625 5e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IPKOFKLA_00626 6.7e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IPKOFKLA_00627 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IPKOFKLA_00628 5.9e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPKOFKLA_00629 5e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IPKOFKLA_00630 3.8e-218 patA 2.6.1.1 E Aminotransferase
IPKOFKLA_00631 9.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IPKOFKLA_00632 5.6e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IPKOFKLA_00633 7.7e-58
IPKOFKLA_00635 1.7e-127 mltD CBM50 M NlpC P60 family protein
IPKOFKLA_00636 5.7e-29
IPKOFKLA_00637 6.7e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
IPKOFKLA_00638 9.8e-32 ykzG S Belongs to the UPF0356 family
IPKOFKLA_00639 3.6e-82
IPKOFKLA_00640 3.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IPKOFKLA_00641 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IPKOFKLA_00642 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IPKOFKLA_00643 2.3e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPKOFKLA_00644 5.4e-275 lpdA 1.8.1.4 C Dehydrogenase
IPKOFKLA_00645 1.5e-46 yktA S Belongs to the UPF0223 family
IPKOFKLA_00646 3.5e-135 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IPKOFKLA_00647 0.0 typA T GTP-binding protein TypA
IPKOFKLA_00648 1.1e-223 ftsW D Belongs to the SEDS family
IPKOFKLA_00649 1.1e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IPKOFKLA_00650 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IPKOFKLA_00651 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPKOFKLA_00652 7.1e-200 ylbL T Belongs to the peptidase S16 family
IPKOFKLA_00653 4.6e-77 comEA L Competence protein ComEA
IPKOFKLA_00654 1.2e-88 comEB 3.5.4.12 F ComE operon protein 2
IPKOFKLA_00655 0.0 comEC S Competence protein ComEC
IPKOFKLA_00656 2.2e-145 holA 2.7.7.7 L DNA polymerase III delta subunit
IPKOFKLA_00657 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
IPKOFKLA_00658 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPKOFKLA_00659 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPKOFKLA_00660 3.5e-163 S Tetratricopeptide repeat
IPKOFKLA_00661 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPKOFKLA_00662 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IPKOFKLA_00663 3.1e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IPKOFKLA_00664 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
IPKOFKLA_00665 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IPKOFKLA_00666 4.9e-08
IPKOFKLA_00667 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IPKOFKLA_00668 2.3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IPKOFKLA_00669 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IPKOFKLA_00670 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IPKOFKLA_00671 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IPKOFKLA_00672 7.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IPKOFKLA_00673 2.5e-88
IPKOFKLA_00674 3e-168 M MucBP domain
IPKOFKLA_00676 4.9e-16
IPKOFKLA_00677 4.9e-16
IPKOFKLA_00680 4.1e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPKOFKLA_00681 2e-211 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IPKOFKLA_00682 3.6e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPKOFKLA_00683 6.6e-35 ynzC S UPF0291 protein
IPKOFKLA_00684 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
IPKOFKLA_00685 7.8e-117 plsC 2.3.1.51 I Acyltransferase
IPKOFKLA_00686 7.8e-140 yabB 2.1.1.223 L Methyltransferase small domain
IPKOFKLA_00687 3.9e-47 yazA L GIY-YIG catalytic domain protein
IPKOFKLA_00688 2.2e-182 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPKOFKLA_00689 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
IPKOFKLA_00690 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IPKOFKLA_00691 1.3e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IPKOFKLA_00692 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IPKOFKLA_00693 4.8e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPKOFKLA_00694 9.9e-138 cdsA 2.7.7.41 I Belongs to the CDS family
IPKOFKLA_00695 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IPKOFKLA_00696 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IPKOFKLA_00697 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPKOFKLA_00698 1.9e-83 rimP J Required for maturation of 30S ribosomal subunits
IPKOFKLA_00699 1.2e-214 nusA K Participates in both transcription termination and antitermination
IPKOFKLA_00700 2.3e-44 ylxR K Protein of unknown function (DUF448)
IPKOFKLA_00701 4.5e-49 ylxQ J ribosomal protein
IPKOFKLA_00702 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPKOFKLA_00703 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IPKOFKLA_00704 2.6e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPKOFKLA_00705 2.2e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IPKOFKLA_00706 7.6e-64
IPKOFKLA_00707 1.2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IPKOFKLA_00708 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPKOFKLA_00709 0.0 dnaK O Heat shock 70 kDa protein
IPKOFKLA_00710 6.8e-196 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IPKOFKLA_00711 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IPKOFKLA_00712 1.5e-48
IPKOFKLA_00714 5e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IPKOFKLA_00715 1.1e-56 K transcriptional regulator PadR family
IPKOFKLA_00716 4.9e-84 XK27_06920 S Protein of unknown function (DUF1700)
IPKOFKLA_00717 1.8e-136 S Putative adhesin
IPKOFKLA_00718 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IPKOFKLA_00719 1.3e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPKOFKLA_00720 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPKOFKLA_00721 3.4e-35 nrdH O Glutaredoxin
IPKOFKLA_00722 2.7e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IPKOFKLA_00723 4.6e-287 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPKOFKLA_00724 4.6e-46 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IPKOFKLA_00725 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPKOFKLA_00726 9.7e-39 S Protein of unknown function (DUF2508)
IPKOFKLA_00727 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPKOFKLA_00728 7.6e-52 yaaQ S Cyclic-di-AMP receptor
IPKOFKLA_00729 1.8e-184 holB 2.7.7.7 L DNA polymerase III
IPKOFKLA_00730 1.7e-57 yabA L Involved in initiation control of chromosome replication
IPKOFKLA_00731 3.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IPKOFKLA_00732 8.1e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
IPKOFKLA_00733 3.4e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IPKOFKLA_00734 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IPKOFKLA_00735 1.3e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IPKOFKLA_00736 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IPKOFKLA_00737 3.6e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IPKOFKLA_00738 4.7e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IPKOFKLA_00739 8e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPKOFKLA_00740 3.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPKOFKLA_00741 7.6e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IPKOFKLA_00742 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPKOFKLA_00743 3.3e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IPKOFKLA_00744 6.9e-228 mtnE 2.6.1.83 E Aminotransferase
IPKOFKLA_00745 6.2e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPKOFKLA_00746 1.2e-309 uup S ABC transporter, ATP-binding protein
IPKOFKLA_00747 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IPKOFKLA_00749 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPKOFKLA_00750 1.8e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IPKOFKLA_00751 1.1e-32 S YbaK proline--tRNA ligase associated domain protein
IPKOFKLA_00752 4.1e-33 S Aminoacyl-tRNA editing domain
IPKOFKLA_00753 2.4e-303 ybeC E amino acid
IPKOFKLA_00754 0.0 ydaO E amino acid
IPKOFKLA_00755 3e-38
IPKOFKLA_00756 6.3e-51 rmaI K Transcriptional regulator
IPKOFKLA_00757 1.4e-152 yaaU EGP Major facilitator Superfamily
IPKOFKLA_00758 4.7e-39 EGP Major facilitator Superfamily
IPKOFKLA_00759 2.1e-123 phoU P Plays a role in the regulation of phosphate uptake
IPKOFKLA_00760 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPKOFKLA_00761 3.2e-153 pstA P Phosphate transport system permease protein PstA
IPKOFKLA_00762 4.7e-152 pstC P probably responsible for the translocation of the substrate across the membrane
IPKOFKLA_00763 9.6e-158 pstS P Phosphate
IPKOFKLA_00764 6.6e-133 K Transcriptional regulatory protein, C-terminal domain protein
IPKOFKLA_00765 8.6e-136 cbiO P ABC transporter
IPKOFKLA_00766 2.1e-133 P Cobalt transport protein
IPKOFKLA_00767 1e-182 nikMN P PDGLE domain
IPKOFKLA_00768 1.3e-72 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPKOFKLA_00769 5.5e-41 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPKOFKLA_00770 2.4e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IPKOFKLA_00771 2.1e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IPKOFKLA_00772 6.9e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IPKOFKLA_00773 3.3e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IPKOFKLA_00774 0.0 ureC 3.5.1.5 E Amidohydrolase family
IPKOFKLA_00775 7.7e-64 ureB 3.5.1.5 E Urease beta subunit
IPKOFKLA_00776 2.9e-45 ureA 3.5.1.5 E Urease, gamma subunit
IPKOFKLA_00777 4.4e-94 ureI S AmiS/UreI family transporter
IPKOFKLA_00778 2.1e-216 P ammonium transporter
IPKOFKLA_00779 1.2e-14 K Transcriptional regulator, HxlR family
IPKOFKLA_00780 1.6e-167
IPKOFKLA_00781 3.7e-96 2.3.1.128 K acetyltransferase
IPKOFKLA_00782 6.6e-23 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPKOFKLA_00783 3.5e-15 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPKOFKLA_00785 2.1e-95
IPKOFKLA_00786 2.8e-60
IPKOFKLA_00787 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPKOFKLA_00788 4.9e-183 S Phosphotransferase system, EIIC
IPKOFKLA_00789 0.0 UW LPXTG-motif cell wall anchor domain protein
IPKOFKLA_00790 0.0 UW LPXTG-motif cell wall anchor domain protein
IPKOFKLA_00791 7.3e-138 IQ KR domain
IPKOFKLA_00792 8.7e-200 fhaB M Rib/alpha-like repeat
IPKOFKLA_00794 9.9e-130 S membrane transporter protein
IPKOFKLA_00795 2.7e-216 yjeM E Amino Acid
IPKOFKLA_00796 2.5e-95 S ABC-type cobalt transport system, permease component
IPKOFKLA_00797 7.8e-239 cbiO1 S ABC transporter, ATP-binding protein
IPKOFKLA_00798 2.3e-111 P Cobalt transport protein
IPKOFKLA_00799 1.6e-52 yvlA
IPKOFKLA_00800 0.0 yjcE P Sodium proton antiporter
IPKOFKLA_00801 2.2e-52 ypaA S Protein of unknown function (DUF1304)
IPKOFKLA_00802 4.8e-190 D Alpha beta
IPKOFKLA_00803 1e-72 K Transcriptional regulator
IPKOFKLA_00804 3.5e-160
IPKOFKLA_00805 4e-16 1.6.5.5 C Zinc-binding dehydrogenase
IPKOFKLA_00806 5.6e-75 1.6.5.5 C Zinc-binding dehydrogenase
IPKOFKLA_00807 6.4e-38 1.6.5.5 C Zinc-binding dehydrogenase
IPKOFKLA_00808 2.1e-255 G PTS system Galactitol-specific IIC component
IPKOFKLA_00809 2.4e-212 EGP Major facilitator Superfamily
IPKOFKLA_00810 8.8e-135 V ABC transporter
IPKOFKLA_00811 3.3e-108
IPKOFKLA_00812 5.2e-14
IPKOFKLA_00813 7.1e-63
IPKOFKLA_00814 8.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
IPKOFKLA_00815 5.1e-81 uspA T universal stress protein
IPKOFKLA_00816 0.0 tetP J elongation factor G
IPKOFKLA_00817 1.4e-167 GK ROK family
IPKOFKLA_00818 1.4e-240 brnQ U Component of the transport system for branched-chain amino acids
IPKOFKLA_00819 9.4e-138 aroD S Serine hydrolase (FSH1)
IPKOFKLA_00820 1.5e-242 yagE E amino acid
IPKOFKLA_00821 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IPKOFKLA_00822 1.5e-132 gntR K UbiC transcription regulator-associated domain protein
IPKOFKLA_00823 1e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IPKOFKLA_00824 1.4e-283 pipD E Dipeptidase
IPKOFKLA_00825 0.0 yfiC V ABC transporter
IPKOFKLA_00826 1.7e-307 lmrA V ABC transporter, ATP-binding protein
IPKOFKLA_00827 1.1e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPKOFKLA_00828 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IPKOFKLA_00829 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPKOFKLA_00830 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
IPKOFKLA_00831 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IPKOFKLA_00832 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IPKOFKLA_00833 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPKOFKLA_00834 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPKOFKLA_00835 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPKOFKLA_00836 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPKOFKLA_00837 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
IPKOFKLA_00838 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPKOFKLA_00839 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPKOFKLA_00840 1.7e-48 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPKOFKLA_00841 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IPKOFKLA_00842 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPKOFKLA_00843 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPKOFKLA_00844 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IPKOFKLA_00845 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPKOFKLA_00846 2.9e-24 rpmD J Ribosomal protein L30
IPKOFKLA_00847 8.9e-64 rplO J Binds to the 23S rRNA
IPKOFKLA_00848 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IPKOFKLA_00849 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IPKOFKLA_00850 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPKOFKLA_00851 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IPKOFKLA_00852 3.6e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IPKOFKLA_00853 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPKOFKLA_00854 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPKOFKLA_00855 1.1e-62 rplQ J Ribosomal protein L17
IPKOFKLA_00856 3e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPKOFKLA_00857 3.4e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPKOFKLA_00858 8.3e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPKOFKLA_00859 5.5e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IPKOFKLA_00860 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPKOFKLA_00861 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IPKOFKLA_00862 5.5e-46 L PFAM transposase IS200-family protein
IPKOFKLA_00863 7.4e-83 S GIY-YIG catalytic domain
IPKOFKLA_00866 9.4e-141 IQ reductase
IPKOFKLA_00867 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
IPKOFKLA_00868 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IPKOFKLA_00869 2.3e-212 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IPKOFKLA_00870 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IPKOFKLA_00871 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPKOFKLA_00872 3.6e-202 camS S sex pheromone
IPKOFKLA_00873 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPKOFKLA_00874 6.5e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IPKOFKLA_00875 2.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPKOFKLA_00876 5.3e-184 yegS 2.7.1.107 G Lipid kinase
IPKOFKLA_00877 3.6e-260 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPKOFKLA_00878 1.2e-32 S Domain of unknown function (DUF4417)
IPKOFKLA_00879 2.9e-19
IPKOFKLA_00880 3e-23
IPKOFKLA_00881 1.7e-15 K Helix-turn-helix domain
IPKOFKLA_00882 1.1e-23 E Zn peptidase
IPKOFKLA_00885 2.8e-13
IPKOFKLA_00886 1.4e-13 L Helix-turn-helix domain
IPKOFKLA_00887 1.4e-261 nox C NADH oxidase
IPKOFKLA_00888 3.3e-86 hmpT S ECF-type riboflavin transporter, S component
IPKOFKLA_00889 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
IPKOFKLA_00890 5.2e-47 1.14.12.17 S Cupin 2, conserved barrel domain protein
IPKOFKLA_00891 1.7e-167 yvgN C Aldo keto reductase
IPKOFKLA_00892 1.1e-135 puuD S peptidase C26
IPKOFKLA_00893 5.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IPKOFKLA_00894 2.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IPKOFKLA_00895 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IPKOFKLA_00896 1.1e-256 malT G Major Facilitator
IPKOFKLA_00897 5.7e-206 phbA 2.3.1.9 I Belongs to the thiolase family
IPKOFKLA_00898 7.3e-172 malR K Transcriptional regulator, LacI family
IPKOFKLA_00899 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IPKOFKLA_00900 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IPKOFKLA_00901 2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPKOFKLA_00902 8.8e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
IPKOFKLA_00904 7.8e-165 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IPKOFKLA_00905 0.0 clpL O associated with various cellular activities
IPKOFKLA_00906 2.7e-32
IPKOFKLA_00907 1.8e-212 patA 2.6.1.1 E Aminotransferase
IPKOFKLA_00908 1.2e-175 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPKOFKLA_00909 2.9e-75 osmC O OsmC-like protein
IPKOFKLA_00911 1.6e-246 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IPKOFKLA_00913 1.1e-138 K LytTr DNA-binding domain
IPKOFKLA_00914 1e-227 2.7.13.3 T GHKL domain
IPKOFKLA_00915 2.7e-112 ywnB S NAD(P)H-binding
IPKOFKLA_00916 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
IPKOFKLA_00917 2.5e-256 nhaC C Na H antiporter NhaC
IPKOFKLA_00918 5.4e-184 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPKOFKLA_00920 1e-101 ydeN S Serine hydrolase
IPKOFKLA_00921 1.3e-61 psiE S Phosphate-starvation-inducible E
IPKOFKLA_00922 1.6e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IPKOFKLA_00924 1.1e-180 S Aldo keto reductase
IPKOFKLA_00925 3.4e-83 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
IPKOFKLA_00926 0.0 L Helicase C-terminal domain protein
IPKOFKLA_00928 4.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
IPKOFKLA_00929 2.8e-54 S Sugar efflux transporter for intercellular exchange
IPKOFKLA_00930 2.1e-126
IPKOFKLA_00931 2.4e-109 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IPKOFKLA_00932 0.0 cadA P P-type ATPase
IPKOFKLA_00933 4.7e-208 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IPKOFKLA_00934 1.4e-72 K Transcriptional regulator
IPKOFKLA_00935 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
IPKOFKLA_00936 8.2e-109 proWZ P ABC transporter permease
IPKOFKLA_00937 9.4e-141 proV E ABC transporter, ATP-binding protein
IPKOFKLA_00938 2.3e-100 proW P ABC transporter, permease protein
IPKOFKLA_00939 2.8e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IPKOFKLA_00940 1.4e-117 clcA P chloride
IPKOFKLA_00941 2.2e-28 clcA P chloride
IPKOFKLA_00942 8.3e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IPKOFKLA_00943 3.1e-103 metI P ABC transporter permease
IPKOFKLA_00944 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPKOFKLA_00945 6.7e-156 metQ1 P Belongs to the nlpA lipoprotein family
IPKOFKLA_00946 2e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IPKOFKLA_00947 4.9e-221 norA EGP Major facilitator Superfamily
IPKOFKLA_00948 4.1e-41 1.3.5.4 S FMN binding
IPKOFKLA_00949 3.5e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IPKOFKLA_00950 1.2e-266 yfnA E amino acid
IPKOFKLA_00951 1.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPKOFKLA_00953 4.1e-54 L Transposase, IS116 IS110 IS902 family
IPKOFKLA_00954 4e-41 L Belongs to the 'phage' integrase family
IPKOFKLA_00955 5.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IPKOFKLA_00956 1.4e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IPKOFKLA_00957 3.8e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
IPKOFKLA_00958 7e-220 patA 2.6.1.1 E Aminotransferase
IPKOFKLA_00959 6.5e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IPKOFKLA_00960 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IPKOFKLA_00961 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IPKOFKLA_00962 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IPKOFKLA_00963 1.8e-147 recO L Involved in DNA repair and RecF pathway recombination
IPKOFKLA_00964 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IPKOFKLA_00965 1.9e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IPKOFKLA_00966 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IPKOFKLA_00967 1.1e-181 phoH T phosphate starvation-inducible protein PhoH
IPKOFKLA_00968 1.1e-167 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IPKOFKLA_00969 1.6e-73 bioY S BioY family
IPKOFKLA_00970 1.7e-262 argH 4.3.2.1 E argininosuccinate lyase
IPKOFKLA_00971 1.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IPKOFKLA_00972 2.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IPKOFKLA_00973 4.3e-69 yqeY S YqeY-like protein
IPKOFKLA_00974 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IPKOFKLA_00975 8e-261 glnPH2 P ABC transporter permease
IPKOFKLA_00976 1.7e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPKOFKLA_00977 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IPKOFKLA_00978 2.7e-165 yniA G Phosphotransferase enzyme family
IPKOFKLA_00979 4.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IPKOFKLA_00980 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPKOFKLA_00981 1e-51
IPKOFKLA_00982 1.4e-125 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IPKOFKLA_00983 1.2e-180 prmA J Ribosomal protein L11 methyltransferase
IPKOFKLA_00984 2.2e-57
IPKOFKLA_00986 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IPKOFKLA_00987 9.5e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IPKOFKLA_00988 1.8e-150 pipD E Dipeptidase
IPKOFKLA_00989 4.6e-82 pipD E Dipeptidase
IPKOFKLA_00990 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IPKOFKLA_00991 2.9e-99 yceD S Uncharacterized ACR, COG1399
IPKOFKLA_00992 6.1e-213 ylbM S Belongs to the UPF0348 family
IPKOFKLA_00993 4.9e-139 yqeM Q Methyltransferase
IPKOFKLA_00994 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IPKOFKLA_00995 8.6e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IPKOFKLA_00996 6.2e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IPKOFKLA_00997 1.9e-47 yhbY J RNA-binding protein
IPKOFKLA_00998 1.2e-216 yqeH S Ribosome biogenesis GTPase YqeH
IPKOFKLA_00999 4.1e-95 yqeG S HAD phosphatase, family IIIA
IPKOFKLA_01000 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IPKOFKLA_01001 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IPKOFKLA_01002 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPKOFKLA_01003 3.3e-172 dnaI L Primosomal protein DnaI
IPKOFKLA_01004 2e-226 dnaB L replication initiation and membrane attachment
IPKOFKLA_01005 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPKOFKLA_01006 1.4e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IPKOFKLA_01007 1.3e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IPKOFKLA_01008 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPKOFKLA_01009 1.4e-119 yoaK S Protein of unknown function (DUF1275)
IPKOFKLA_01010 9.3e-119 ybhL S Belongs to the BI1 family
IPKOFKLA_01011 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IPKOFKLA_01012 7.9e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPKOFKLA_01013 6.6e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IPKOFKLA_01014 2e-55 ytzB S Small secreted protein
IPKOFKLA_01015 2.6e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
IPKOFKLA_01016 2.2e-179 iolS C Aldo keto reductase
IPKOFKLA_01017 1.8e-249 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IPKOFKLA_01018 6.9e-83 A chlorophyll binding
IPKOFKLA_01019 2.9e-45 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
IPKOFKLA_01020 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IPKOFKLA_01021 1.3e-216 ecsB U ABC transporter
IPKOFKLA_01022 1e-136 ecsA V ABC transporter, ATP-binding protein
IPKOFKLA_01023 8.3e-78 hit FG histidine triad
IPKOFKLA_01025 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IPKOFKLA_01026 0.0 L AAA domain
IPKOFKLA_01027 2.8e-213 yhaO L Ser Thr phosphatase family protein
IPKOFKLA_01028 9.4e-38 yheA S Belongs to the UPF0342 family
IPKOFKLA_01029 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IPKOFKLA_01032 1.3e-35 S Bacteriophage holin family
IPKOFKLA_01033 4.7e-57 S Bacteriophage holin of superfamily 6 (Holin_LLH)
IPKOFKLA_01034 4.4e-200 3.5.1.104 M hydrolase, family 25
IPKOFKLA_01035 2.5e-34 S Bacteriophage abortive infection AbiH
IPKOFKLA_01036 2.3e-30 S Protein of unknown function (DUF2929)
IPKOFKLA_01037 0.0 dnaE 2.7.7.7 L DNA polymerase
IPKOFKLA_01038 8e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IPKOFKLA_01039 3e-167 cvfB S S1 domain
IPKOFKLA_01040 3.5e-163 xerD D recombinase XerD
IPKOFKLA_01041 1.6e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPKOFKLA_01042 4.8e-140 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IPKOFKLA_01043 1.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPKOFKLA_01044 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IPKOFKLA_01045 1.6e-70 L Belongs to the 'phage' integrase family
IPKOFKLA_01046 9.3e-26
IPKOFKLA_01049 8.1e-76 E IrrE N-terminal-like domain
IPKOFKLA_01050 1.4e-48 K Cro/C1-type HTH DNA-binding domain
IPKOFKLA_01051 1.3e-20
IPKOFKLA_01052 9.6e-111 S Protein of unknown function (DUF3102)
IPKOFKLA_01054 5.4e-08
IPKOFKLA_01058 3.8e-07
IPKOFKLA_01060 1.7e-54 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IPKOFKLA_01061 4.6e-131 S Putative HNHc nuclease
IPKOFKLA_01062 1e-34 L Psort location Cytoplasmic, score
IPKOFKLA_01065 3.7e-36
IPKOFKLA_01066 2.7e-31
IPKOFKLA_01067 3.4e-74 rusA L Endodeoxyribonuclease RusA
IPKOFKLA_01075 1.6e-162
IPKOFKLA_01076 2.3e-122 dck 2.7.1.74 F deoxynucleoside kinase
IPKOFKLA_01081 2.5e-74 S Transcriptional regulator, RinA family
IPKOFKLA_01085 2.7e-78 L Belongs to the 'phage' integrase family
IPKOFKLA_01086 1.3e-10 E Zn peptidase
IPKOFKLA_01087 2.8e-17 XK27_10050 K Peptidase S24-like
IPKOFKLA_01092 4.4e-29 L Psort location Cytoplasmic, score
IPKOFKLA_01120 6.1e-54 srtA 3.4.22.70 M sortase family
IPKOFKLA_01121 8.1e-16
IPKOFKLA_01126 3.7e-25 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IPKOFKLA_01127 7.6e-24 S YoeB-like toxin of bacterial type II toxin-antitoxin system
IPKOFKLA_01128 1e-58 ruvB 3.6.4.12 L four-way junction helicase activity
IPKOFKLA_01130 1.1e-62
IPKOFKLA_01132 6.8e-36 lytE M Lysin motif
IPKOFKLA_01134 1.4e-19 D nuclear chromosome segregation
IPKOFKLA_01135 5.2e-22
IPKOFKLA_01136 2.8e-16 S Domain of unknown function (DUF4868)
IPKOFKLA_01137 8.9e-11
IPKOFKLA_01143 7.6e-39 S sequence-specific DNA binding transcription factor activity
IPKOFKLA_01144 1.5e-113 pnuC H nicotinamide mononucleotide transporter
IPKOFKLA_01147 5.8e-23 N mRNA binding
IPKOFKLA_01148 3.3e-57 S HicB_like antitoxin of bacterial toxin-antitoxin system
IPKOFKLA_01149 1.4e-177 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IPKOFKLA_01163 4.3e-50 L HNH nucleases
IPKOFKLA_01164 4.2e-80 L Phage terminase, small subunit
IPKOFKLA_01165 1.4e-267 S Phage Terminase
IPKOFKLA_01167 4.9e-145 S portal protein
IPKOFKLA_01168 1.7e-88 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
IPKOFKLA_01169 1.5e-131 S Phage capsid family
IPKOFKLA_01170 1.8e-43 S Phage gp6-like head-tail connector protein
IPKOFKLA_01171 4e-38 S Phage head-tail joining protein
IPKOFKLA_01172 1.3e-20
IPKOFKLA_01173 5.7e-25
IPKOFKLA_01174 1.2e-65 S Phage tail tube protein
IPKOFKLA_01175 1.6e-19
IPKOFKLA_01176 5.8e-224 M Phage tail tape measure protein TP901
IPKOFKLA_01177 3.1e-113 S Phage tail protein
IPKOFKLA_01178 1.8e-201 M Prophage endopeptidase tail
IPKOFKLA_01179 2.8e-14 tcdA2 GT2,GT4 LM gp58-like protein
IPKOFKLA_01182 6.8e-23 S GDSL-like Lipase/Acylhydrolase
IPKOFKLA_01183 9.4e-163
IPKOFKLA_01187 2.3e-27
IPKOFKLA_01188 8.2e-58 hol S COG5546 Small integral membrane protein
IPKOFKLA_01189 1.7e-173 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IPKOFKLA_01191 5.8e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IPKOFKLA_01192 3e-187 ypbB 5.1.3.1 S Helix-turn-helix domain
IPKOFKLA_01193 6.2e-263 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IPKOFKLA_01194 8.5e-14 M Lysin motif
IPKOFKLA_01195 3.9e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IPKOFKLA_01196 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
IPKOFKLA_01197 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IPKOFKLA_01198 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IPKOFKLA_01199 1.5e-236 S Tetratricopeptide repeat protein
IPKOFKLA_01200 1.8e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IPKOFKLA_01201 0.0 yfmR S ABC transporter, ATP-binding protein
IPKOFKLA_01202 2.5e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IPKOFKLA_01203 1.1e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPKOFKLA_01204 1.7e-111 hlyIII S protein, hemolysin III
IPKOFKLA_01205 6.4e-151 DegV S EDD domain protein, DegV family
IPKOFKLA_01206 2.6e-169 ypmR E lipolytic protein G-D-S-L family
IPKOFKLA_01207 1.3e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IPKOFKLA_01208 1.7e-34 yozE S Belongs to the UPF0346 family
IPKOFKLA_01209 8.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IPKOFKLA_01210 7.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPKOFKLA_01211 7.8e-160 dprA LU DNA protecting protein DprA
IPKOFKLA_01212 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPKOFKLA_01213 7.9e-168 lacX 5.1.3.3 G Aldose 1-epimerase
IPKOFKLA_01214 9.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IPKOFKLA_01215 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPKOFKLA_01216 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPKOFKLA_01217 5.4e-83 F NUDIX domain
IPKOFKLA_01218 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
IPKOFKLA_01219 1.1e-68 yqkB S Belongs to the HesB IscA family
IPKOFKLA_01220 6e-49
IPKOFKLA_01222 1.8e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IPKOFKLA_01223 1.3e-61 asp S Asp23 family, cell envelope-related function
IPKOFKLA_01224 2.1e-25
IPKOFKLA_01225 8.5e-96
IPKOFKLA_01226 4.9e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IPKOFKLA_01227 1.2e-183 K Transcriptional regulator, LacI family
IPKOFKLA_01228 2.4e-232 gntT EG Gluconate
IPKOFKLA_01229 2.5e-294 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IPKOFKLA_01230 3.2e-95 K Acetyltransferase (GNAT) domain
IPKOFKLA_01231 5.4e-47
IPKOFKLA_01232 4.8e-23
IPKOFKLA_01233 0.0 nylA 3.5.1.4 J Belongs to the amidase family
IPKOFKLA_01234 5e-44
IPKOFKLA_01235 3.3e-54 yhaI S Protein of unknown function (DUF805)
IPKOFKLA_01236 1.6e-24
IPKOFKLA_01237 1.3e-14 IQ KR domain
IPKOFKLA_01238 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IPKOFKLA_01239 7.7e-193 hsdM 2.1.1.72 V type I restriction-modification system
IPKOFKLA_01240 3.3e-60 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain protein
IPKOFKLA_01241 8.9e-178 L Belongs to the 'phage' integrase family
IPKOFKLA_01242 1.3e-71 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IPKOFKLA_01243 4.1e-167 L restriction endonuclease
IPKOFKLA_01244 4.6e-94 mrr L restriction endonuclease
IPKOFKLA_01245 5.5e-21
IPKOFKLA_01246 0.0 L PLD-like domain
IPKOFKLA_01248 8.4e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IPKOFKLA_01249 7.8e-105 T Ion transport 2 domain protein
IPKOFKLA_01250 0.0 S Bacterial membrane protein YfhO
IPKOFKLA_01251 3.4e-206 G Transporter, major facilitator family protein
IPKOFKLA_01252 1.5e-64 L PFAM Integrase catalytic region
IPKOFKLA_01253 7.2e-09
IPKOFKLA_01254 2.5e-155 P Belongs to the nlpA lipoprotein family
IPKOFKLA_01255 3.9e-12
IPKOFKLA_01256 1.4e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IPKOFKLA_01257 1.3e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPKOFKLA_01258 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
IPKOFKLA_01259 1.6e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IPKOFKLA_01260 3.8e-21 S Protein of unknown function (DUF3042)
IPKOFKLA_01261 2.6e-67 yqhL P Rhodanese-like protein
IPKOFKLA_01262 9.6e-183 glk 2.7.1.2 G Glucokinase
IPKOFKLA_01263 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
IPKOFKLA_01264 1.6e-112 gluP 3.4.21.105 S Peptidase, S54 family
IPKOFKLA_01265 1.3e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IPKOFKLA_01266 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IPKOFKLA_01267 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IPKOFKLA_01268 0.0 S membrane
IPKOFKLA_01269 1.3e-69 yneR S Belongs to the HesB IscA family
IPKOFKLA_01270 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IPKOFKLA_01271 7.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
IPKOFKLA_01272 1.2e-114 rlpA M PFAM NLP P60 protein
IPKOFKLA_01273 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPKOFKLA_01274 1.5e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IPKOFKLA_01275 6.7e-59 yodB K Transcriptional regulator, HxlR family
IPKOFKLA_01276 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IPKOFKLA_01277 4.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPKOFKLA_01278 3.2e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IPKOFKLA_01279 2.6e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPKOFKLA_01280 1.8e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IPKOFKLA_01281 1.5e-231 V MatE
IPKOFKLA_01282 1.9e-267 yjeM E Amino Acid
IPKOFKLA_01283 3.1e-278 arlS 2.7.13.3 T Histidine kinase
IPKOFKLA_01284 1.5e-121 K response regulator
IPKOFKLA_01285 2e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IPKOFKLA_01286 5.7e-120 radC L DNA repair protein
IPKOFKLA_01287 1.7e-179 mreB D cell shape determining protein MreB
IPKOFKLA_01288 7.7e-152 mreC M Involved in formation and maintenance of cell shape
IPKOFKLA_01289 3.3e-92 mreD M rod shape-determining protein MreD
IPKOFKLA_01290 3.2e-102 glnP P ABC transporter permease
IPKOFKLA_01291 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPKOFKLA_01292 2.6e-160 aatB ET ABC transporter substrate-binding protein
IPKOFKLA_01293 6.6e-229 ymfF S Peptidase M16 inactive domain protein
IPKOFKLA_01294 2.5e-247 ymfH S Peptidase M16
IPKOFKLA_01295 3.1e-139 ymfM S Helix-turn-helix domain
IPKOFKLA_01296 3.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPKOFKLA_01297 1.1e-228 cinA 3.5.1.42 S Belongs to the CinA family
IPKOFKLA_01298 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPKOFKLA_01299 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
IPKOFKLA_01300 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPKOFKLA_01301 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IPKOFKLA_01302 3.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IPKOFKLA_01303 4.5e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IPKOFKLA_01304 6.7e-201 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IPKOFKLA_01305 6.2e-31 yajC U Preprotein translocase
IPKOFKLA_01306 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IPKOFKLA_01307 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IPKOFKLA_01308 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPKOFKLA_01309 2.5e-134
IPKOFKLA_01310 3.2e-242 ydaM M Glycosyl transferase
IPKOFKLA_01311 2.2e-223 G Glycosyl hydrolases family 8
IPKOFKLA_01312 7.8e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IPKOFKLA_01313 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
IPKOFKLA_01314 5.8e-239 ktrB P Potassium uptake protein
IPKOFKLA_01315 6.9e-116 ktrA P domain protein
IPKOFKLA_01316 6.5e-80 Q Methyltransferase
IPKOFKLA_01317 2.6e-231 mntH P H( )-stimulated, divalent metal cation uptake system
IPKOFKLA_01318 4.7e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IPKOFKLA_01319 5.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IPKOFKLA_01320 1.5e-84 S NADPH-dependent FMN reductase
IPKOFKLA_01321 1.2e-172 MA20_14895 S Conserved hypothetical protein 698
IPKOFKLA_01322 1.5e-166 L transposase, IS605 OrfB family
IPKOFKLA_01323 5.5e-111 I alpha/beta hydrolase fold
IPKOFKLA_01324 2.4e-126 lsa S ABC transporter
IPKOFKLA_01325 6.7e-173 yfeX P Peroxidase
IPKOFKLA_01326 3.8e-271 arcD S C4-dicarboxylate anaerobic carrier
IPKOFKLA_01327 9.2e-253 ytjP 3.5.1.18 E Dipeptidase
IPKOFKLA_01328 1.3e-57 ubiE_1 Q Methyltransferase
IPKOFKLA_01329 3.7e-152 nikA E Bacterial extracellular solute-binding proteins, family 5 Middle
IPKOFKLA_01330 1e-48 nikB P Binding-protein-dependent transport system inner membrane component
IPKOFKLA_01331 1.3e-55 EP N-terminal TM domain of oligopeptide transport permease C
IPKOFKLA_01332 3.7e-52 P Belongs to the ABC transporter superfamily
IPKOFKLA_01333 7.8e-76
IPKOFKLA_01334 9.8e-180
IPKOFKLA_01335 2.9e-182 fecB P Periplasmic binding protein
IPKOFKLA_01336 1.2e-138 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
IPKOFKLA_01337 8.3e-131 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPKOFKLA_01338 7.8e-79 S Flavodoxin
IPKOFKLA_01339 2.2e-64 moaE 2.8.1.12 H MoaE protein
IPKOFKLA_01340 6.4e-35 moaD 2.8.1.12 H ThiS family
IPKOFKLA_01341 7.8e-219 narK P Transporter, major facilitator family protein
IPKOFKLA_01342 8.4e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
IPKOFKLA_01343 1.2e-180
IPKOFKLA_01344 1.6e-18
IPKOFKLA_01345 2.3e-116 nreC K PFAM regulatory protein LuxR
IPKOFKLA_01346 7.4e-189 comP 2.7.13.3 F Sensor histidine kinase
IPKOFKLA_01347 8.8e-44
IPKOFKLA_01348 1.2e-103 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IPKOFKLA_01349 9.7e-83 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IPKOFKLA_01350 7.9e-227 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
IPKOFKLA_01351 9.2e-81 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IPKOFKLA_01352 7.2e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
IPKOFKLA_01353 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPKOFKLA_01354 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
IPKOFKLA_01355 2.3e-99 narJ C nitrate reductase molybdenum cofactor assembly chaperone
IPKOFKLA_01356 1.9e-129 narI 1.7.5.1 C Nitrate reductase
IPKOFKLA_01357 2.7e-152 EG EamA-like transporter family
IPKOFKLA_01358 7.2e-118 L Integrase
IPKOFKLA_01359 1.1e-158 rssA S Phospholipase, patatin family
IPKOFKLA_01361 9e-199 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
IPKOFKLA_01362 3.3e-47 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
IPKOFKLA_01363 0.0 UW LPXTG-motif cell wall anchor domain protein
IPKOFKLA_01365 2.3e-159 metQ_4 P Belongs to the nlpA lipoprotein family
IPKOFKLA_01366 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IPKOFKLA_01367 3.9e-122 O Zinc-dependent metalloprotease
IPKOFKLA_01368 1.3e-113 S Membrane
IPKOFKLA_01369 9.7e-197 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IPKOFKLA_01370 5.5e-77 S Domain of unknown function (DUF4767)
IPKOFKLA_01371 4.3e-13
IPKOFKLA_01372 1.1e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
IPKOFKLA_01373 5.6e-97 wecD3 K PFAM GCN5-related N-acetyltransferase
IPKOFKLA_01374 5.6e-77 P CorA-like Mg2+ transporter protein
IPKOFKLA_01375 9.6e-62 P CorA-like Mg2+ transporter protein
IPKOFKLA_01376 1.6e-79
IPKOFKLA_01377 2.8e-111 M Lysin motif
IPKOFKLA_01378 4.3e-198 EGP Major facilitator Superfamily
IPKOFKLA_01379 5.6e-98 ywlG S Belongs to the UPF0340 family
IPKOFKLA_01380 4.1e-43 yrzL S Belongs to the UPF0297 family
IPKOFKLA_01381 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPKOFKLA_01382 6.1e-48 yrzB S Belongs to the UPF0473 family
IPKOFKLA_01383 1e-85 cvpA S Colicin V production protein
IPKOFKLA_01384 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IPKOFKLA_01385 6.1e-54 trxA O Belongs to the thioredoxin family
IPKOFKLA_01386 5.1e-96 yslB S Protein of unknown function (DUF2507)
IPKOFKLA_01387 3.2e-144 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IPKOFKLA_01388 2.4e-104 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IPKOFKLA_01389 7.6e-94 S Phosphoesterase
IPKOFKLA_01390 3.6e-76 ykuL S (CBS) domain
IPKOFKLA_01391 1e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
IPKOFKLA_01392 4e-148 ykuT M mechanosensitive ion channel
IPKOFKLA_01393 1.2e-36 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IPKOFKLA_01394 5.6e-08
IPKOFKLA_01395 9.4e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IPKOFKLA_01396 4.5e-183 ccpA K catabolite control protein A
IPKOFKLA_01397 2.5e-134
IPKOFKLA_01398 1e-131 yebC K Transcriptional regulatory protein
IPKOFKLA_01399 4.3e-183 comGA NU Type II IV secretion system protein
IPKOFKLA_01400 1.7e-182 comGB NU type II secretion system
IPKOFKLA_01401 7.9e-46 comGC U competence protein ComGC
IPKOFKLA_01402 1.4e-77 NU general secretion pathway protein
IPKOFKLA_01403 7.1e-41
IPKOFKLA_01404 2.4e-69
IPKOFKLA_01405 1.3e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
IPKOFKLA_01406 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPKOFKLA_01407 5.7e-117 S Calcineurin-like phosphoesterase
IPKOFKLA_01408 5.7e-100 yutD S Protein of unknown function (DUF1027)
IPKOFKLA_01409 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IPKOFKLA_01410 5.4e-113 S Protein of unknown function (DUF1461)
IPKOFKLA_01411 1.6e-109 dedA S SNARE-like domain protein
IPKOFKLA_01412 0.0 fhaB M Rib/alpha-like repeat
IPKOFKLA_01413 1.7e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IPKOFKLA_01414 3.9e-197 XK27_09615 S reductase
IPKOFKLA_01415 2.7e-106 nqr 1.5.1.36 S reductase
IPKOFKLA_01416 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPKOFKLA_01417 1.3e-182 K Transcriptional regulator, LacI family
IPKOFKLA_01418 5.2e-259 G Major Facilitator
IPKOFKLA_01419 1.5e-266 G Major Facilitator
IPKOFKLA_01420 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
IPKOFKLA_01421 1.1e-285 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
IPKOFKLA_01422 9.4e-262 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
IPKOFKLA_01423 7.9e-264 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IPKOFKLA_01424 5.4e-71
IPKOFKLA_01425 2e-98 K Transcriptional regulator, TetR family
IPKOFKLA_01426 4.6e-24
IPKOFKLA_01427 3.7e-97
IPKOFKLA_01428 6.4e-42
IPKOFKLA_01429 5.7e-19
IPKOFKLA_01430 1.9e-150 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IPKOFKLA_01431 8.3e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IPKOFKLA_01432 1.7e-102 fic D Fic/DOC family
IPKOFKLA_01433 3.3e-71
IPKOFKLA_01434 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
IPKOFKLA_01435 2.8e-96 L nuclease
IPKOFKLA_01436 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IPKOFKLA_01437 3.4e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IPKOFKLA_01438 7.9e-19 M Glycosyl hydrolases family 25
IPKOFKLA_01439 9.1e-144 ywqE 3.1.3.48 GM PHP domain protein
IPKOFKLA_01440 0.0 snf 2.7.11.1 KL domain protein
IPKOFKLA_01443 5e-249 mmuP E amino acid
IPKOFKLA_01444 4.4e-118 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IPKOFKLA_01445 4.5e-230 ndh 1.6.99.3 C NADH dehydrogenase
IPKOFKLA_01446 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IPKOFKLA_01447 1.7e-307 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IPKOFKLA_01448 1.4e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IPKOFKLA_01449 7.2e-272 cydA 1.10.3.14 C ubiquinol oxidase
IPKOFKLA_01450 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IPKOFKLA_01451 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPKOFKLA_01452 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
IPKOFKLA_01453 5.8e-252 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IPKOFKLA_01454 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPKOFKLA_01455 0.0 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
IPKOFKLA_01456 3e-95 E Amino acid permease
IPKOFKLA_01457 2.8e-95 cadD P Cadmium resistance transporter
IPKOFKLA_01458 1.3e-52 cadX K Bacterial regulatory protein, arsR family
IPKOFKLA_01459 3.1e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPKOFKLA_01460 1e-182 arsB 1.20.4.1 P Sodium Bile acid symporter family
IPKOFKLA_01461 1.8e-42 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
IPKOFKLA_01462 1.4e-14 S Helix-turn-helix domain
IPKOFKLA_01463 6.6e-102 S NgoFVII restriction endonuclease
IPKOFKLA_01464 3e-157 dcm 2.1.1.37 H cytosine-specific methyltransferase
IPKOFKLA_01465 1.1e-48 vsr L DNA mismatch endonuclease Vsr
IPKOFKLA_01469 1.8e-10
IPKOFKLA_01470 4.4e-83 L Phage integrase, N-terminal SAM-like domain
IPKOFKLA_01471 9e-37 L Single-strand binding protein family
IPKOFKLA_01472 1.4e-102 L Replication initiation factor
IPKOFKLA_01473 2.4e-19 S Lysin motif
IPKOFKLA_01474 3.3e-56 L Lactococcus lactis RepB C-terminus
IPKOFKLA_01475 1e-91 L Integrase
IPKOFKLA_01477 3.9e-201 xerS L Belongs to the 'phage' integrase family
IPKOFKLA_01479 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IPKOFKLA_01480 4.2e-77 marR K Transcriptional regulator, MarR family
IPKOFKLA_01481 5.8e-81 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPKOFKLA_01482 7.8e-85 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPKOFKLA_01483 5.5e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPKOFKLA_01484 6.5e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IPKOFKLA_01485 4.6e-129 IQ reductase
IPKOFKLA_01486 5.9e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IPKOFKLA_01487 1e-70 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IPKOFKLA_01488 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IPKOFKLA_01489 2.3e-39 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IPKOFKLA_01490 3.7e-207 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IPKOFKLA_01491 2.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPKOFKLA_01492 5.7e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IPKOFKLA_01493 2e-18 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IPKOFKLA_01494 4.8e-58 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IPKOFKLA_01503 4.1e-83 L PFAM transposase IS200-family protein
IPKOFKLA_01504 8.9e-54
IPKOFKLA_01505 3.5e-112 frnE Q DSBA-like thioredoxin domain
IPKOFKLA_01506 6.7e-164 I alpha/beta hydrolase fold
IPKOFKLA_01508 1.4e-46 yrvD S Pfam:DUF1049
IPKOFKLA_01509 3.1e-150 3.1.3.102, 3.1.3.104 S hydrolase
IPKOFKLA_01510 3.6e-90 ntd 2.4.2.6 F Nucleoside
IPKOFKLA_01511 3.4e-21
IPKOFKLA_01512 1.1e-39 S Alpha/beta hydrolase of unknown function (DUF915)
IPKOFKLA_01513 3.7e-91 S Alpha/beta hydrolase of unknown function (DUF915)
IPKOFKLA_01514 4.7e-114 yviA S Protein of unknown function (DUF421)
IPKOFKLA_01515 5.9e-71 S Protein of unknown function (DUF3290)
IPKOFKLA_01516 1.3e-41 ybaN S Protein of unknown function (DUF454)
IPKOFKLA_01517 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPKOFKLA_01518 1.1e-150 endA V DNA/RNA non-specific endonuclease
IPKOFKLA_01519 3e-254 yifK E Amino acid permease
IPKOFKLA_01521 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPKOFKLA_01522 1.2e-230 N Uncharacterized conserved protein (DUF2075)
IPKOFKLA_01523 5.1e-122 S SNARE associated Golgi protein
IPKOFKLA_01524 0.0 uvrA3 L excinuclease ABC, A subunit
IPKOFKLA_01525 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPKOFKLA_01526 2.5e-136 S DUF218 domain
IPKOFKLA_01527 0.0 ubiB S ABC1 family
IPKOFKLA_01528 1.9e-245 yhdP S Transporter associated domain
IPKOFKLA_01529 5e-75 copY K Copper transport repressor CopY TcrY
IPKOFKLA_01530 3.3e-245 EGP Major facilitator Superfamily
IPKOFKLA_01531 1.9e-72 yeaL S UPF0756 membrane protein
IPKOFKLA_01532 3.3e-76 yphH S Cupin domain
IPKOFKLA_01533 3.9e-63 K Transcriptional regulator
IPKOFKLA_01534 1.2e-152 1.1.1.346 C Aldo keto reductase
IPKOFKLA_01535 1.4e-38 gcvR T Belongs to the UPF0237 family
IPKOFKLA_01536 2.6e-80 XK27_08635 S UPF0210 protein
IPKOFKLA_01537 1.4e-148 XK27_08635 S UPF0210 protein
IPKOFKLA_01538 1.8e-95 K Acetyltransferase (GNAT) domain
IPKOFKLA_01539 1.7e-159 S Alpha beta hydrolase
IPKOFKLA_01540 5.5e-158 gspA M family 8
IPKOFKLA_01541 5e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IPKOFKLA_01542 9.4e-94
IPKOFKLA_01543 6.4e-162 degV S EDD domain protein, DegV family
IPKOFKLA_01544 0.0 FbpA K Fibronectin-binding protein
IPKOFKLA_01545 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IPKOFKLA_01546 3.1e-206 carA 6.3.5.5 F Belongs to the CarA family
IPKOFKLA_01547 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IPKOFKLA_01548 7.7e-71 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPKOFKLA_01549 1.5e-65 esbA S Family of unknown function (DUF5322)
IPKOFKLA_01550 4e-71 rnhA 3.1.26.4 L Ribonuclease HI
IPKOFKLA_01551 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IPKOFKLA_01552 1.1e-83 F Belongs to the NrdI family
IPKOFKLA_01553 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IPKOFKLA_01554 1.7e-102 ypsA S Belongs to the UPF0398 family
IPKOFKLA_01555 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IPKOFKLA_01556 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IPKOFKLA_01557 1.3e-160 EG EamA-like transporter family
IPKOFKLA_01558 2.8e-123 dnaD L DnaD domain protein
IPKOFKLA_01559 4.9e-85 ypmB S Protein conserved in bacteria
IPKOFKLA_01560 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IPKOFKLA_01561 5.3e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IPKOFKLA_01562 1.1e-165 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IPKOFKLA_01563 2.1e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IPKOFKLA_01564 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IPKOFKLA_01565 4.9e-87 S Protein of unknown function (DUF1440)
IPKOFKLA_01566 0.0 rafA 3.2.1.22 G alpha-galactosidase
IPKOFKLA_01567 3.7e-185 galR K Periplasmic binding protein-like domain
IPKOFKLA_01568 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IPKOFKLA_01569 2.1e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IPKOFKLA_01570 2.2e-123 lrgB M LrgB-like family
IPKOFKLA_01571 1.9e-66 lrgA S LrgA family
IPKOFKLA_01572 9.2e-130 lytT K response regulator receiver
IPKOFKLA_01573 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
IPKOFKLA_01574 1.5e-147 f42a O Band 7 protein
IPKOFKLA_01575 3.8e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IPKOFKLA_01576 1.7e-153 yitU 3.1.3.104 S hydrolase
IPKOFKLA_01577 2.7e-38 S Cytochrome B5
IPKOFKLA_01578 6.3e-100 nreC K PFAM regulatory protein LuxR
IPKOFKLA_01579 4.4e-158 hipB K Helix-turn-helix
IPKOFKLA_01580 4.7e-57 yitW S Iron-sulfur cluster assembly protein
IPKOFKLA_01581 2.3e-270 sufB O assembly protein SufB
IPKOFKLA_01582 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
IPKOFKLA_01583 3.1e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPKOFKLA_01584 9.6e-239 sufD O FeS assembly protein SufD
IPKOFKLA_01585 3.2e-144 sufC O FeS assembly ATPase SufC
IPKOFKLA_01586 4.2e-32 feoA P FeoA domain
IPKOFKLA_01587 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IPKOFKLA_01588 3.1e-267 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IPKOFKLA_01589 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IPKOFKLA_01590 2.6e-64 ydiI Q Thioesterase superfamily
IPKOFKLA_01591 7.1e-109 yvrI K RNA polymerase sigma factor, sigma-70 family
IPKOFKLA_01592 5.4e-77 L PFAM Integrase catalytic region
IPKOFKLA_01593 2.4e-127 3.2.1.23, 3.2.1.89 G arabinogalactan endo-1,4-beta-galactosidase activity
IPKOFKLA_01594 3.9e-63 gntR1 K Transcriptional regulator, GntR family
IPKOFKLA_01595 3.7e-154 V ABC transporter, ATP-binding protein
IPKOFKLA_01596 8.7e-114
IPKOFKLA_01597 2.3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
IPKOFKLA_01598 4.9e-100 S Pfam:DUF3816
IPKOFKLA_01599 0.0 clpE O Belongs to the ClpA ClpB family
IPKOFKLA_01600 2.2e-27
IPKOFKLA_01601 4e-38 ptsH G phosphocarrier protein HPR
IPKOFKLA_01602 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPKOFKLA_01603 1.8e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IPKOFKLA_01604 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
IPKOFKLA_01605 1.9e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IPKOFKLA_01606 8.9e-100 S dextransucrase activity
IPKOFKLA_01607 1.4e-164 yueF S AI-2E family transporter
IPKOFKLA_01608 5.1e-44 S Psort location CytoplasmicMembrane, score
IPKOFKLA_01609 7.2e-220 S Psort location CytoplasmicMembrane, score
IPKOFKLA_01610 1.4e-222 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IPKOFKLA_01611 3.1e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IPKOFKLA_01612 5.2e-85 L PFAM transposase IS200-family protein
IPKOFKLA_01613 0.0 lacZ 3.2.1.23 G -beta-galactosidase
IPKOFKLA_01614 0.0 lacS G Transporter
IPKOFKLA_01615 2.4e-184 lacR K Transcriptional regulator
IPKOFKLA_01616 6.6e-84
IPKOFKLA_01617 9.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
IPKOFKLA_01618 4.2e-53 S Mazg nucleotide pyrophosphohydrolase
IPKOFKLA_01619 3.4e-35
IPKOFKLA_01620 2.7e-247 steT_1 E amino acid
IPKOFKLA_01621 9.5e-135 puuD S peptidase C26
IPKOFKLA_01623 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPKOFKLA_01624 1.4e-88
IPKOFKLA_01625 1.5e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IPKOFKLA_01626 3.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IPKOFKLA_01627 2.1e-177 M Glycosyltransferase like family 2
IPKOFKLA_01628 3e-27
IPKOFKLA_01629 8.2e-122 M repeat protein
IPKOFKLA_01630 1.2e-51 M KxYKxGKxW signal domain protein
IPKOFKLA_01631 3.3e-85 L PFAM transposase IS200-family protein
IPKOFKLA_01632 1.6e-141 acmD M repeat protein
IPKOFKLA_01634 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
IPKOFKLA_01635 1.1e-181 L Helix-turn-helix domain
IPKOFKLA_01636 2.1e-66 K Psort location Cytoplasmic, score
IPKOFKLA_01637 8.8e-35 K DNA binding
IPKOFKLA_01638 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
IPKOFKLA_01639 2.4e-222 mod 2.1.1.72, 3.1.21.5 L DNA methylase
IPKOFKLA_01640 2.1e-214 L Transposase
IPKOFKLA_01641 2.6e-90 L Integrase
IPKOFKLA_01642 2.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IPKOFKLA_01643 3.3e-15 K Transcriptional regulator, LacI family
IPKOFKLA_01644 2.9e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPKOFKLA_01645 6.3e-57 yitW S Pfam:DUF59
IPKOFKLA_01646 1.4e-77 L PFAM Integrase catalytic region
IPKOFKLA_01647 8.3e-78 L PFAM Integrase catalytic region
IPKOFKLA_01648 3.4e-266 pipD E Dipeptidase
IPKOFKLA_01649 8e-204 coiA 3.6.4.12 S Competence protein
IPKOFKLA_01650 1e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IPKOFKLA_01651 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IPKOFKLA_01652 2.3e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IPKOFKLA_01654 1.8e-17 QT PucR C-terminal helix-turn-helix domain
IPKOFKLA_01656 2.6e-26 S Protein of unknown function (DUF4065)
IPKOFKLA_01658 9.8e-21 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IPKOFKLA_01659 2.1e-97 E Amino acid permease
IPKOFKLA_01660 4.1e-242 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
IPKOFKLA_01661 1.3e-233 pbuG S permease
IPKOFKLA_01662 4.1e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IPKOFKLA_01663 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IPKOFKLA_01664 3e-136 S Belongs to the UPF0246 family
IPKOFKLA_01665 1.2e-137 S Membrane
IPKOFKLA_01666 8.1e-75 4.4.1.5 E Glyoxalase
IPKOFKLA_01667 1.2e-21
IPKOFKLA_01668 2.5e-86 yueI S Protein of unknown function (DUF1694)
IPKOFKLA_01669 4.6e-241 rarA L recombination factor protein RarA
IPKOFKLA_01670 5.7e-46
IPKOFKLA_01671 4.3e-83 usp6 T universal stress protein
IPKOFKLA_01672 5.9e-205 araR K Transcriptional regulator
IPKOFKLA_01673 2.3e-156 ytbE 1.1.1.346 S Aldo keto reductase
IPKOFKLA_01674 3.2e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
IPKOFKLA_01675 2.4e-283 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IPKOFKLA_01676 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IPKOFKLA_01677 0.0 araB 2.7.1.16 G carbohydrate kinase FGGY
IPKOFKLA_01678 7.5e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPKOFKLA_01679 9.6e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IPKOFKLA_01680 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IPKOFKLA_01681 1.8e-47 gcvH E glycine cleavage
IPKOFKLA_01682 3.2e-220 rodA D Belongs to the SEDS family
IPKOFKLA_01683 1e-31 S Protein of unknown function (DUF2969)
IPKOFKLA_01684 5.5e-178 mbl D Cell shape determining protein MreB Mrl
IPKOFKLA_01685 2.5e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPKOFKLA_01686 2.2e-33 ywzB S Protein of unknown function (DUF1146)
IPKOFKLA_01687 5.9e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IPKOFKLA_01688 5.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPKOFKLA_01689 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPKOFKLA_01690 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPKOFKLA_01691 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPKOFKLA_01692 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPKOFKLA_01693 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPKOFKLA_01694 4.7e-123 atpB C it plays a direct role in the translocation of protons across the membrane
IPKOFKLA_01695 6.5e-232 pyrP F Permease
IPKOFKLA_01696 7e-128 yibF S overlaps another CDS with the same product name
IPKOFKLA_01697 1.3e-191 yibE S overlaps another CDS with the same product name
IPKOFKLA_01698 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPKOFKLA_01699 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IPKOFKLA_01700 3.5e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPKOFKLA_01701 1.4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IPKOFKLA_01702 6.8e-164 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IPKOFKLA_01703 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPKOFKLA_01704 6e-108 tdk 2.7.1.21 F thymidine kinase
IPKOFKLA_01705 1.7e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
IPKOFKLA_01706 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
IPKOFKLA_01707 6.7e-222 arcD U Amino acid permease
IPKOFKLA_01708 1.5e-261 E Arginine ornithine antiporter
IPKOFKLA_01709 2.7e-79 argR K Regulates arginine biosynthesis genes
IPKOFKLA_01710 9.1e-239 arcA 3.5.3.6 E Arginine
IPKOFKLA_01711 2e-186 ampC V Beta-lactamase
IPKOFKLA_01712 1.2e-18
IPKOFKLA_01713 0.0 M domain protein
IPKOFKLA_01714 2.2e-90
IPKOFKLA_01716 2.2e-38 yjcE P Sodium proton antiporter
IPKOFKLA_01717 8.5e-150 yjcE P Sodium proton antiporter
IPKOFKLA_01718 3.6e-57
IPKOFKLA_01720 1.7e-87
IPKOFKLA_01721 0.0 copA 3.6.3.54 P P-type ATPase
IPKOFKLA_01722 8.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IPKOFKLA_01723 5.6e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IPKOFKLA_01724 1.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IPKOFKLA_01725 3.9e-162 EG EamA-like transporter family
IPKOFKLA_01726 2.1e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
IPKOFKLA_01727 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IPKOFKLA_01728 1.2e-154 KT YcbB domain
IPKOFKLA_01729 3.3e-299 xylB 2.7.1.17 G Belongs to the FGGY kinase family
IPKOFKLA_01730 1.3e-270 xylA 5.3.1.5 G Belongs to the xylose isomerase family
IPKOFKLA_01731 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
IPKOFKLA_01732 6e-20 pgdA 3.5.1.104 G polysaccharide deacetylase
IPKOFKLA_01733 0.0 3.2.1.55 GH51 G Right handed beta helix region
IPKOFKLA_01734 6.9e-289 xynT G MFS/sugar transport protein
IPKOFKLA_01735 1.9e-172 rhaS2 K Transcriptional regulator, AraC family
IPKOFKLA_01736 6.2e-260 xylT EGP Major facilitator Superfamily
IPKOFKLA_01738 3e-215 xylR GK ROK family
IPKOFKLA_01739 8.5e-28
IPKOFKLA_01740 3.4e-263 pgi 5.3.1.9 G Belongs to the GPI family
IPKOFKLA_01741 4.4e-101 lacA 2.3.1.79 S Transferase hexapeptide repeat
IPKOFKLA_01742 2.6e-155 glcU U sugar transport
IPKOFKLA_01743 2.7e-269 yclK 2.7.13.3 T Histidine kinase
IPKOFKLA_01744 4.4e-132 K response regulator
IPKOFKLA_01746 5.3e-78 lytE M Lysin motif
IPKOFKLA_01747 2.8e-143 XK27_02985 S Cof-like hydrolase
IPKOFKLA_01748 2.3e-81 K Transcriptional regulator
IPKOFKLA_01749 0.0 oatA I Acyltransferase
IPKOFKLA_01750 8.7e-53
IPKOFKLA_01751 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IPKOFKLA_01752 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPKOFKLA_01753 1.1e-124 ybbR S YbbR-like protein
IPKOFKLA_01754 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IPKOFKLA_01755 4e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IPKOFKLA_01756 5.6e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPKOFKLA_01757 1.2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
IPKOFKLA_01758 1.2e-114 yjbH Q Thioredoxin
IPKOFKLA_01759 1.3e-40 L PFAM Integrase catalytic region
IPKOFKLA_01760 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IPKOFKLA_01761 6.2e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IPKOFKLA_01762 3.8e-49 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IPKOFKLA_01763 1.4e-50
IPKOFKLA_01764 0.0 S SEC-C Motif Domain Protein
IPKOFKLA_01765 3.8e-82 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IPKOFKLA_01766 5.3e-283 O Arylsulfotransferase (ASST)
IPKOFKLA_01786 3.3e-25 M Glycosyltransferase like family 2
IPKOFKLA_01787 1.5e-17 Z012_10770 M Domain of unknown function (DUF1919)
IPKOFKLA_01788 8.1e-196 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IPKOFKLA_01789 1.9e-125 3.2.1.96, 3.5.1.28 GH73 M repeat protein
IPKOFKLA_01790 7.2e-96 L Helix-turn-helix domain
IPKOFKLA_01791 8.7e-140 L hmm pf00665
IPKOFKLA_01792 3.8e-48 S Domain of unknown function (DUF4393)
IPKOFKLA_01793 4.3e-92 L Belongs to the 'phage' integrase family
IPKOFKLA_01794 2.4e-11 ftsZ D Cell surface antigen C-terminus
IPKOFKLA_01795 9.7e-13 D Psort location Cellwall, score
IPKOFKLA_01796 4.3e-33 XK27_00515 D Glucan-binding protein C
IPKOFKLA_01798 9.1e-52 L Protein of unknown function (DUF3991)
IPKOFKLA_01799 3.8e-136 topA2 5.99.1.2 G Topoisomerase IA
IPKOFKLA_01801 6.7e-148 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IPKOFKLA_01806 3.5e-196 U TraM recognition site of TraD and TraG
IPKOFKLA_01807 1e-64
IPKOFKLA_01809 8.1e-24
IPKOFKLA_01810 3e-180 U type IV secretory pathway VirB4
IPKOFKLA_01812 8e-38 M CHAP domain
IPKOFKLA_01816 2.5e-29
IPKOFKLA_01819 4.4e-51 E Filamentation induced by cAMP protein fic
IPKOFKLA_01820 6.6e-78 S Fic/DOC family
IPKOFKLA_01821 4.2e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPKOFKLA_01822 8.2e-51 S Iron-sulfur cluster assembly protein
IPKOFKLA_01823 1e-151
IPKOFKLA_01824 9.2e-176
IPKOFKLA_01825 1.9e-86 dut S Protein conserved in bacteria
IPKOFKLA_01828 5.8e-112 K Transcriptional regulator
IPKOFKLA_01829 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
IPKOFKLA_01830 1.6e-54 ysxB J Cysteine protease Prp
IPKOFKLA_01831 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IPKOFKLA_01832 3.8e-128 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IPKOFKLA_01833 1.4e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IPKOFKLA_01834 8.9e-111 J 2'-5' RNA ligase superfamily
IPKOFKLA_01835 2.2e-70 yqhY S Asp23 family, cell envelope-related function
IPKOFKLA_01836 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IPKOFKLA_01837 1.2e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPKOFKLA_01838 2.3e-227 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPKOFKLA_01839 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPKOFKLA_01840 2.2e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IPKOFKLA_01841 4.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IPKOFKLA_01842 5.6e-77 argR K Regulates arginine biosynthesis genes
IPKOFKLA_01843 2.1e-262 recN L May be involved in recombinational repair of damaged DNA
IPKOFKLA_01844 1.4e-53
IPKOFKLA_01845 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IPKOFKLA_01846 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IPKOFKLA_01847 4.6e-211 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IPKOFKLA_01848 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPKOFKLA_01849 3.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IPKOFKLA_01850 6.5e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IPKOFKLA_01851 3.8e-131 stp 3.1.3.16 T phosphatase
IPKOFKLA_01852 0.0 KLT serine threonine protein kinase
IPKOFKLA_01853 2.7e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IPKOFKLA_01854 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IPKOFKLA_01855 5.3e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
IPKOFKLA_01856 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IPKOFKLA_01857 4.7e-58 asp S Asp23 family, cell envelope-related function
IPKOFKLA_01858 0.0 yloV S DAK2 domain fusion protein YloV
IPKOFKLA_01859 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IPKOFKLA_01860 2.2e-185 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IPKOFKLA_01861 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPKOFKLA_01862 8e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IPKOFKLA_01863 0.0 smc D Required for chromosome condensation and partitioning
IPKOFKLA_01864 9.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IPKOFKLA_01865 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IPKOFKLA_01866 1.3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IPKOFKLA_01867 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IPKOFKLA_01868 4.1e-40 ylqC S Belongs to the UPF0109 family
IPKOFKLA_01869 3.8e-90 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IPKOFKLA_01870 1.3e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IPKOFKLA_01871 6.8e-262 yfnA E amino acid
IPKOFKLA_01872 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IPKOFKLA_01873 1.1e-259 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IPKOFKLA_01883 7.7e-205 S Uncharacterised protein family (UPF0236)
IPKOFKLA_01884 3.4e-186 L Transposase
IPKOFKLA_01885 7.2e-116 azlC E azaleucine resistance protein AzlC
IPKOFKLA_01886 3e-48 azlD E Branched-chain amino acid transport
IPKOFKLA_01887 8.3e-114 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IPKOFKLA_01889 7.2e-29 S GyrI-like small molecule binding domain
IPKOFKLA_01890 3.7e-47 S GyrI-like small molecule binding domain
IPKOFKLA_01891 8e-120 yhiD S MgtC family
IPKOFKLA_01892 6.2e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IPKOFKLA_01893 5.3e-192 V Beta-lactamase
IPKOFKLA_01894 5.3e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPKOFKLA_01895 4.5e-88 XK27_08850 J Aminoacyl-tRNA editing domain
IPKOFKLA_01896 3e-20 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IPKOFKLA_01897 8.6e-118 K LytTr DNA-binding domain
IPKOFKLA_01898 2.6e-196 2.7.13.3 T GHKL domain
IPKOFKLA_01902 2.1e-43 mleP3 S Membrane transport protein
IPKOFKLA_01903 1e-122 T Transcriptional regulatory protein, C terminal
IPKOFKLA_01904 1.5e-239 T GHKL domain
IPKOFKLA_01905 3e-108 S Peptidase propeptide and YPEB domain
IPKOFKLA_01906 1.8e-115 P nitric oxide dioxygenase activity
IPKOFKLA_01907 2.4e-10 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
IPKOFKLA_01908 2.8e-54 yphJ 4.1.1.44 S decarboxylase
IPKOFKLA_01909 1.3e-31 S Oxidoreductase, aldo keto reductase family protein
IPKOFKLA_01910 4.1e-110 S Oxidoreductase, aldo keto reductase family protein
IPKOFKLA_01911 7.4e-71 C Flavodoxin
IPKOFKLA_01912 7.5e-92 padC Q Phenolic acid decarboxylase
IPKOFKLA_01913 3.5e-56 padR K Virulence activator alpha C-term
IPKOFKLA_01914 1.4e-165 ypuA S Protein of unknown function (DUF1002)
IPKOFKLA_01915 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
IPKOFKLA_01916 7.8e-152 K Transcriptional regulator
IPKOFKLA_01917 9.6e-158 akr5f 1.1.1.346 S reductase
IPKOFKLA_01918 2.4e-62 yneR
IPKOFKLA_01919 5e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
IPKOFKLA_01920 1.4e-17
IPKOFKLA_01921 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IPKOFKLA_01922 1.4e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
IPKOFKLA_01923 1.3e-29 yjaB_1 K Acetyltransferase (GNAT) domain
IPKOFKLA_01924 1.3e-88 folT S ECF transporter, substrate-specific component
IPKOFKLA_01925 0.0 pepN 3.4.11.2 E aminopeptidase
IPKOFKLA_01926 3.4e-112 ylbE GM NAD dependent epimerase dehydratase family protein
IPKOFKLA_01927 5.4e-253 pepC 3.4.22.40 E aminopeptidase
IPKOFKLA_01928 1.3e-205 EGP Major facilitator Superfamily
IPKOFKLA_01929 1.7e-227
IPKOFKLA_01930 7.1e-80 K Transcriptional regulator, HxlR family
IPKOFKLA_01931 4.5e-106 XK27_02070 S Nitroreductase family
IPKOFKLA_01932 8.1e-51 hxlR K Transcriptional regulator, HxlR family
IPKOFKLA_01933 3e-10 GM NmrA-like family
IPKOFKLA_01934 3.6e-73 elaA S Gnat family
IPKOFKLA_01935 2.7e-38 S Cytochrome B5
IPKOFKLA_01936 5.4e-09 S Cytochrome B5
IPKOFKLA_01937 1.7e-40 S Cytochrome B5
IPKOFKLA_01938 8.8e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
IPKOFKLA_01940 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPKOFKLA_01941 4.1e-240 E amino acid
IPKOFKLA_01942 2.9e-251 npp S type I phosphodiesterase nucleotide pyrophosphatase
IPKOFKLA_01943 8.1e-20 yxiO S Vacuole effluxer Atg22 like
IPKOFKLA_01944 2.3e-117 yxiO S Vacuole effluxer Atg22 like
IPKOFKLA_01945 2.3e-32 yxiO S Vacuole effluxer Atg22 like
IPKOFKLA_01947 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPKOFKLA_01948 1.6e-22
IPKOFKLA_01949 3e-290 mntH P H( )-stimulated, divalent metal cation uptake system
IPKOFKLA_01950 1.7e-190 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
IPKOFKLA_01951 4.4e-86 ygfC K transcriptional regulator (TetR family)
IPKOFKLA_01952 5.4e-171 hrtB V ABC transporter permease
IPKOFKLA_01953 6.7e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IPKOFKLA_01954 0.0 yhcA V ABC transporter, ATP-binding protein
IPKOFKLA_01955 1.3e-37
IPKOFKLA_01956 4.1e-50 czrA K Transcriptional regulator, ArsR family
IPKOFKLA_01957 1e-240 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IPKOFKLA_01958 1.3e-171 scrR K Transcriptional regulator, LacI family
IPKOFKLA_01959 1e-24
IPKOFKLA_01960 1.6e-106
IPKOFKLA_01961 8.3e-205 yttB EGP Major facilitator Superfamily
IPKOFKLA_01962 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
IPKOFKLA_01963 8.5e-87
IPKOFKLA_01964 1.5e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
IPKOFKLA_01967 9.7e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IPKOFKLA_01968 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPKOFKLA_01969 4.4e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IPKOFKLA_01970 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPKOFKLA_01971 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IPKOFKLA_01972 7.2e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IPKOFKLA_01973 9.8e-67 yabR J RNA binding
IPKOFKLA_01974 6.6e-57 divIC D Septum formation initiator
IPKOFKLA_01975 2.1e-39 yabO J S4 domain protein
IPKOFKLA_01976 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IPKOFKLA_01977 5.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IPKOFKLA_01978 6.9e-113 S (CBS) domain
IPKOFKLA_01979 2e-146 tesE Q hydratase
IPKOFKLA_01980 9.8e-241 codA 3.5.4.1 F cytosine deaminase
IPKOFKLA_01981 4.4e-250 U Belongs to the purine-cytosine permease (2.A.39) family
IPKOFKLA_01982 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
IPKOFKLA_01983 8.7e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPKOFKLA_01984 1.9e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IPKOFKLA_01986 8e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPKOFKLA_01987 1.3e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
IPKOFKLA_01988 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPKOFKLA_01989 2.2e-251 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IPKOFKLA_01990 1.4e-164 glsA 3.5.1.2 E Belongs to the glutaminase family
IPKOFKLA_01991 0.0 sprD D Domain of Unknown Function (DUF1542)
IPKOFKLA_01992 5.3e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IPKOFKLA_01993 2.6e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IPKOFKLA_01994 1.5e-158 htpX O Belongs to the peptidase M48B family
IPKOFKLA_01995 3.5e-92 lemA S LemA family
IPKOFKLA_01996 2.3e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPKOFKLA_01997 1.2e-120 pgm3 G Belongs to the phosphoglycerate mutase family
IPKOFKLA_01998 2.6e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IPKOFKLA_01999 4.4e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IPKOFKLA_02000 2.5e-124 srtA 3.4.22.70 M sortase family
IPKOFKLA_02001 6.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
IPKOFKLA_02002 5.7e-239 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPKOFKLA_02003 4.6e-41 rpmE2 J Ribosomal protein L31
IPKOFKLA_02004 4e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPKOFKLA_02005 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IPKOFKLA_02006 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IPKOFKLA_02007 3e-66 ywiB S Domain of unknown function (DUF1934)
IPKOFKLA_02008 3.9e-145 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IPKOFKLA_02009 3.8e-270 ywfO S HD domain protein
IPKOFKLA_02010 8.4e-148 yxeH S hydrolase
IPKOFKLA_02011 2.6e-47
IPKOFKLA_02012 3.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPKOFKLA_02013 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPKOFKLA_02014 6.5e-148 purR 2.4.2.7 F pur operon repressor
IPKOFKLA_02015 4.7e-119 znuB U ABC 3 transport family
IPKOFKLA_02016 3.8e-122 fhuC P ABC transporter
IPKOFKLA_02017 3.3e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
IPKOFKLA_02018 7.6e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPKOFKLA_02019 6.8e-37 veg S Biofilm formation stimulator VEG
IPKOFKLA_02020 1.9e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IPKOFKLA_02021 3.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IPKOFKLA_02022 2.4e-155 tatD L hydrolase, TatD family
IPKOFKLA_02023 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPKOFKLA_02024 8.1e-162 yunF F Protein of unknown function DUF72
IPKOFKLA_02026 8.8e-130 cobB K SIR2 family
IPKOFKLA_02027 1.1e-175
IPKOFKLA_02028 1.5e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IPKOFKLA_02029 1.8e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IPKOFKLA_02030 2.9e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IPKOFKLA_02031 4.8e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
IPKOFKLA_02032 8.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
IPKOFKLA_02033 0.0 helD 3.6.4.12 L DNA helicase
IPKOFKLA_02034 1.3e-202 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IPKOFKLA_02035 1.9e-197 clcA P chloride
IPKOFKLA_02036 1.2e-37 L PFAM Integrase catalytic region
IPKOFKLA_02037 1.4e-77 L PFAM Integrase catalytic region
IPKOFKLA_02039 6.4e-42 L PFAM Integrase catalytic region
IPKOFKLA_02040 4.4e-77 uspA T universal stress protein
IPKOFKLA_02041 3.3e-80 K AsnC family
IPKOFKLA_02042 2e-231 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPKOFKLA_02043 2.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
IPKOFKLA_02044 5e-179 galR K Transcriptional regulator
IPKOFKLA_02045 3.8e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IPKOFKLA_02046 2.9e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPKOFKLA_02047 2.1e-177 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
IPKOFKLA_02048 4.9e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
IPKOFKLA_02049 2e-91 yxkA S Phosphatidylethanolamine-binding protein
IPKOFKLA_02050 9.1e-36
IPKOFKLA_02051 2.6e-52
IPKOFKLA_02052 1e-204
IPKOFKLA_02053 2.9e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IPKOFKLA_02054 1.2e-135 pnuC H nicotinamide mononucleotide transporter
IPKOFKLA_02055 7.8e-157 ytbE 1.1.1.346 S Aldo keto reductase
IPKOFKLA_02056 4.1e-124 K response regulator
IPKOFKLA_02057 5.5e-178 T PhoQ Sensor
IPKOFKLA_02058 1.1e-133 macB2 V ABC transporter, ATP-binding protein
IPKOFKLA_02059 0.0 ysaB V FtsX-like permease family
IPKOFKLA_02060 1.7e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IPKOFKLA_02061 2.7e-166 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IPKOFKLA_02062 6.7e-53 K helix_turn_helix, mercury resistance
IPKOFKLA_02063 6.6e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPKOFKLA_02064 2.4e-193 EGP Major facilitator Superfamily
IPKOFKLA_02065 2.5e-86 ymdB S Macro domain protein
IPKOFKLA_02066 1.2e-109 K Helix-turn-helix domain
IPKOFKLA_02067 0.0 pepO 3.4.24.71 O Peptidase family M13
IPKOFKLA_02068 4.6e-48
IPKOFKLA_02069 4.6e-233 S Putative metallopeptidase domain
IPKOFKLA_02070 5.6e-206 3.1.3.1 S associated with various cellular activities
IPKOFKLA_02071 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IPKOFKLA_02072 5.4e-65 yeaO S Protein of unknown function, DUF488
IPKOFKLA_02074 1.2e-115 yrkL S Flavodoxin-like fold
IPKOFKLA_02075 3.6e-54
IPKOFKLA_02076 1.5e-18 S Domain of unknown function (DUF4767)
IPKOFKLA_02077 2.9e-136 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IPKOFKLA_02078 3.1e-49
IPKOFKLA_02079 1.6e-199 nrnB S DHHA1 domain
IPKOFKLA_02080 6e-230 S Uncharacterized protein conserved in bacteria (DUF2325)
IPKOFKLA_02081 2.2e-249 brnQ U Component of the transport system for branched-chain amino acids
IPKOFKLA_02082 1.3e-105 NU mannosyl-glycoprotein
IPKOFKLA_02083 1.6e-143 S Putative ABC-transporter type IV
IPKOFKLA_02084 1.7e-274 S ABC transporter, ATP-binding protein
IPKOFKLA_02085 4.1e-10
IPKOFKLA_02087 5.1e-105 S Protein of unknown function (DUF3278)
IPKOFKLA_02089 7e-75 M PFAM NLP P60 protein
IPKOFKLA_02090 9.8e-183 ABC-SBP S ABC transporter
IPKOFKLA_02091 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IPKOFKLA_02092 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
IPKOFKLA_02093 8.8e-96 P Cadmium resistance transporter
IPKOFKLA_02094 2.4e-56 K Transcriptional regulator, ArsR family
IPKOFKLA_02095 3.2e-55 trxA O Belongs to the thioredoxin family
IPKOFKLA_02096 2.3e-131 terC P membrane
IPKOFKLA_02097 1.8e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IPKOFKLA_02098 2.4e-167 corA P CorA-like Mg2+ transporter protein
IPKOFKLA_02099 2e-282 pipD E Dipeptidase
IPKOFKLA_02100 5.6e-242 pbuX F xanthine permease
IPKOFKLA_02101 2.4e-251 nhaC C Na H antiporter NhaC
IPKOFKLA_02102 2.4e-284 S C4-dicarboxylate anaerobic carrier
IPKOFKLA_02103 7.2e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
IPKOFKLA_02104 1.3e-41
IPKOFKLA_02105 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IPKOFKLA_02106 3.4e-35 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IPKOFKLA_02107 7.8e-109 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IPKOFKLA_02108 4.6e-156 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IPKOFKLA_02109 3.8e-35
IPKOFKLA_02110 1.7e-162 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IPKOFKLA_02111 1e-12 ydiN 5.4.99.5 G Major Facilitator
IPKOFKLA_02112 6.5e-54 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IPKOFKLA_02113 5.1e-127 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPKOFKLA_02114 7.4e-132 ydiN G Major Facilitator Superfamily
IPKOFKLA_02116 2.3e-17 I alpha/beta hydrolase fold
IPKOFKLA_02119 7.2e-37 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IPKOFKLA_02120 7.1e-41 L PFAM Integrase catalytic region
IPKOFKLA_02121 5.9e-214 uhpT EGP Major facilitator Superfamily
IPKOFKLA_02122 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
IPKOFKLA_02123 1e-129 ponA V Beta-lactamase enzyme family
IPKOFKLA_02124 3.8e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IPKOFKLA_02125 4.3e-74
IPKOFKLA_02126 7e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IPKOFKLA_02127 8.1e-28
IPKOFKLA_02128 7.6e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
IPKOFKLA_02129 9.5e-294 L PFAM plasmid pRiA4b ORF-3 family protein
IPKOFKLA_02130 1.9e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
IPKOFKLA_02131 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPKOFKLA_02132 1.2e-160 mleR K LysR family
IPKOFKLA_02133 2.9e-309 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IPKOFKLA_02134 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IPKOFKLA_02135 3.6e-268 frdC 1.3.5.4 C FAD binding domain
IPKOFKLA_02136 4.9e-252 yflS P Sodium:sulfate symporter transmembrane region
IPKOFKLA_02137 6.3e-157 mleR K LysR family
IPKOFKLA_02138 1.2e-250 yjjP S Putative threonine/serine exporter
IPKOFKLA_02139 1.9e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
IPKOFKLA_02140 1.4e-270 emrY EGP Major facilitator Superfamily
IPKOFKLA_02141 3.3e-183 I Alpha beta
IPKOFKLA_02142 1.2e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
IPKOFKLA_02143 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IPKOFKLA_02145 1.2e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IPKOFKLA_02146 1e-120 S Domain of unknown function (DUF4811)
IPKOFKLA_02147 3.6e-269 lmrB EGP Major facilitator Superfamily
IPKOFKLA_02148 5.2e-75 merR K MerR HTH family regulatory protein
IPKOFKLA_02149 7.2e-56
IPKOFKLA_02150 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPKOFKLA_02151 1.6e-216 S CAAX protease self-immunity
IPKOFKLA_02152 6.1e-109 glnP P ABC transporter permease
IPKOFKLA_02153 3.2e-110 gluC P ABC transporter permease
IPKOFKLA_02154 2.2e-151 glnH ET ABC transporter
IPKOFKLA_02155 5.3e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IPKOFKLA_02156 5.5e-83 usp1 T Belongs to the universal stress protein A family
IPKOFKLA_02157 7.6e-110 S VIT family
IPKOFKLA_02158 1.7e-117 S membrane
IPKOFKLA_02159 3.5e-166 czcD P cation diffusion facilitator family transporter
IPKOFKLA_02160 2e-123 sirR K iron dependent repressor
IPKOFKLA_02161 7.9e-31 cspC K Cold shock protein
IPKOFKLA_02162 2.1e-129 thrE S Putative threonine/serine exporter
IPKOFKLA_02163 3e-81 S Threonine/Serine exporter, ThrE
IPKOFKLA_02164 2.3e-119 lssY 3.6.1.27 I phosphatase
IPKOFKLA_02165 5.4e-11 2.3.1.128 J Acetyltransferase (GNAT) domain
IPKOFKLA_02166 1.1e-275 lysP E amino acid
IPKOFKLA_02167 5.6e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IPKOFKLA_02173 4.7e-12
IPKOFKLA_02174 1.7e-179 S Hydrolases of the alpha beta superfamily
IPKOFKLA_02175 2.7e-196 adhP 1.1.1.1 C alcohol dehydrogenase
IPKOFKLA_02176 1.7e-76 ctsR K Belongs to the CtsR family
IPKOFKLA_02177 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IPKOFKLA_02178 1e-110 K Bacterial regulatory proteins, tetR family
IPKOFKLA_02179 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPKOFKLA_02180 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPKOFKLA_02181 2.2e-202 ykiI
IPKOFKLA_02182 5.7e-118 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
IPKOFKLA_02183 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPKOFKLA_02184 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IPKOFKLA_02185 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPKOFKLA_02186 1.3e-162 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IPKOFKLA_02187 1.9e-30 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)