ORF_ID e_value Gene_name EC_number CAZy COGs Description
APDCDNMF_00001 1.4e-44 S RelE-like toxin of type II toxin-antitoxin system HigB
APDCDNMF_00002 4.4e-38 higA K Helix-turn-helix XRE-family like proteins
APDCDNMF_00003 2.6e-112 L Helix-turn-helix domain
APDCDNMF_00005 2.2e-29 L Helix-turn-helix domain
APDCDNMF_00006 2.3e-63 L Helix-turn-helix domain
APDCDNMF_00007 3.1e-110 L PFAM Integrase catalytic region
APDCDNMF_00008 3.1e-33 L PFAM Integrase catalytic region
APDCDNMF_00009 2.8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
APDCDNMF_00010 3.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
APDCDNMF_00011 1.5e-112 gph 3.1.3.18 S HAD hydrolase, family IA, variant
APDCDNMF_00012 1.7e-249 yagE E amino acid
APDCDNMF_00013 2.9e-84 dps P Belongs to the Dps family
APDCDNMF_00014 0.0 pacL 3.6.3.8 P P-type ATPase
APDCDNMF_00015 3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
APDCDNMF_00016 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
APDCDNMF_00017 2.2e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
APDCDNMF_00018 4.5e-146 potB P ABC transporter permease
APDCDNMF_00019 7.1e-139 potC P ABC transporter permease
APDCDNMF_00020 2.5e-208 potD P ABC transporter
APDCDNMF_00021 1.3e-230
APDCDNMF_00022 1.1e-234 EGP Sugar (and other) transporter
APDCDNMF_00023 1.3e-254 yfnA E Amino Acid
APDCDNMF_00024 2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
APDCDNMF_00025 3.2e-98 gmk2 2.7.4.8 F Guanylate kinase
APDCDNMF_00026 1.5e-82 zur P Belongs to the Fur family
APDCDNMF_00027 3.1e-17 3.2.1.14 GH18
APDCDNMF_00028 5.4e-150
APDCDNMF_00029 8.3e-38 pspC KT PspC domain protein
APDCDNMF_00030 1.6e-94 K Transcriptional regulator (TetR family)
APDCDNMF_00031 1.9e-234 V domain protein
APDCDNMF_00032 5.1e-179 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APDCDNMF_00034 6.6e-35 S Transglycosylase associated protein
APDCDNMF_00035 1.6e-233 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APDCDNMF_00036 1.9e-126 G phosphoglycerate mutase
APDCDNMF_00037 1.2e-115 dedA S SNARE associated Golgi protein
APDCDNMF_00038 0.0 helD 3.6.4.12 L DNA helicase
APDCDNMF_00039 7.9e-244 nox C NADH oxidase
APDCDNMF_00040 2.9e-254 nox C NADH oxidase
APDCDNMF_00041 2.5e-158 EG EamA-like transporter family
APDCDNMF_00042 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APDCDNMF_00043 1.3e-176 coaA 2.7.1.33 F Pantothenic acid kinase
APDCDNMF_00044 3e-223 S cog cog1373
APDCDNMF_00046 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
APDCDNMF_00048 2.3e-163 sthIM 2.1.1.72 L DNA methylase
APDCDNMF_00049 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
APDCDNMF_00050 1.1e-218 oxlT P Major Facilitator Superfamily
APDCDNMF_00051 6.2e-157 spoU 2.1.1.185 J Methyltransferase
APDCDNMF_00052 2.1e-37 rmeB K transcriptional regulator, MerR family
APDCDNMF_00053 7.2e-08 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
APDCDNMF_00054 9.8e-27 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
APDCDNMF_00055 1.5e-99 crp_2 K Cyclic nucleotide-binding domain
APDCDNMF_00056 3.3e-127 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
APDCDNMF_00057 1.2e-137 pnuC H nicotinamide mononucleotide transporter
APDCDNMF_00058 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
APDCDNMF_00059 8.8e-99 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
APDCDNMF_00060 2.5e-44 L Helix-turn-helix domain
APDCDNMF_00061 1.1e-62 L Helix-turn-helix domain
APDCDNMF_00062 2e-48 L PFAM transposase IS200-family protein
APDCDNMF_00063 2.8e-16 S Domain of unknown function (DUF4868)
APDCDNMF_00067 1.9e-127 L Helix-turn-helix domain
APDCDNMF_00068 2.4e-248 fucP G Major Facilitator Superfamily
APDCDNMF_00069 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
APDCDNMF_00070 3.8e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APDCDNMF_00071 4.7e-168 murB 1.3.1.98 M Cell wall formation
APDCDNMF_00072 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
APDCDNMF_00073 3.8e-75 S PAS domain
APDCDNMF_00074 3e-87 K Acetyltransferase (GNAT) domain
APDCDNMF_00075 6.5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
APDCDNMF_00076 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
APDCDNMF_00077 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APDCDNMF_00078 2.6e-103 yxjI
APDCDNMF_00079 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
APDCDNMF_00080 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APDCDNMF_00081 2.8e-145 est 3.1.1.1 S Serine aminopeptidase, S33
APDCDNMF_00082 1.8e-34 secG U Preprotein translocase
APDCDNMF_00083 6.9e-292 clcA P chloride
APDCDNMF_00084 1.2e-247 yifK E Amino acid permease
APDCDNMF_00085 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APDCDNMF_00086 6.3e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APDCDNMF_00087 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
APDCDNMF_00088 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APDCDNMF_00090 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APDCDNMF_00091 3.7e-241 glpT G Major Facilitator Superfamily
APDCDNMF_00092 8.8e-15
APDCDNMF_00094 3.1e-170 whiA K May be required for sporulation
APDCDNMF_00095 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
APDCDNMF_00096 1.7e-162 rapZ S Displays ATPase and GTPase activities
APDCDNMF_00097 1.1e-245 steT E amino acid
APDCDNMF_00098 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APDCDNMF_00099 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APDCDNMF_00100 6.9e-14
APDCDNMF_00101 5.1e-116 yfbR S HD containing hydrolase-like enzyme
APDCDNMF_00102 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
APDCDNMF_00103 3.9e-87 ykhA 3.1.2.20 I Thioesterase superfamily
APDCDNMF_00104 5.9e-163 aatB ET PFAM extracellular solute-binding protein, family 3
APDCDNMF_00105 6.9e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
APDCDNMF_00106 3.9e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APDCDNMF_00107 5.6e-166 lutA C Cysteine-rich domain
APDCDNMF_00108 9.8e-288 lutB C 4Fe-4S dicluster domain
APDCDNMF_00109 2.8e-134 yrjD S LUD domain
APDCDNMF_00110 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APDCDNMF_00111 5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
APDCDNMF_00112 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APDCDNMF_00113 6.6e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APDCDNMF_00114 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
APDCDNMF_00115 5.9e-31 KT PspC domain protein
APDCDNMF_00116 7.8e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APDCDNMF_00117 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APDCDNMF_00118 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APDCDNMF_00119 7.5e-126 comFC S Competence protein
APDCDNMF_00120 4.1e-253 comFA L Helicase C-terminal domain protein
APDCDNMF_00121 5.7e-140 L PFAM transposase IS116 IS110 IS902
APDCDNMF_00122 9.8e-112 yvyE 3.4.13.9 S YigZ family
APDCDNMF_00123 3e-44 L Helix-turn-helix domain
APDCDNMF_00124 1.1e-62 L Helix-turn-helix domain
APDCDNMF_00125 4.4e-77 uspA T universal stress protein
APDCDNMF_00126 3.3e-80 K AsnC family
APDCDNMF_00127 2e-231 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APDCDNMF_00128 2.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
APDCDNMF_00129 5e-179 galR K Transcriptional regulator
APDCDNMF_00130 3.8e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
APDCDNMF_00131 2.9e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APDCDNMF_00132 2.1e-177 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
APDCDNMF_00133 4.9e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
APDCDNMF_00134 2e-91 yxkA S Phosphatidylethanolamine-binding protein
APDCDNMF_00135 9.1e-36
APDCDNMF_00136 2.6e-52
APDCDNMF_00137 1e-204
APDCDNMF_00138 2.9e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APDCDNMF_00139 1.2e-135 pnuC H nicotinamide mononucleotide transporter
APDCDNMF_00140 7.8e-157 ytbE 1.1.1.346 S Aldo keto reductase
APDCDNMF_00141 4.1e-124 K response regulator
APDCDNMF_00142 5.5e-178 T PhoQ Sensor
APDCDNMF_00143 1.1e-133 macB2 V ABC transporter, ATP-binding protein
APDCDNMF_00144 0.0 ysaB V FtsX-like permease family
APDCDNMF_00145 1.7e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
APDCDNMF_00146 2.7e-166 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APDCDNMF_00147 6.7e-53 K helix_turn_helix, mercury resistance
APDCDNMF_00148 6.6e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APDCDNMF_00149 2.4e-193 EGP Major facilitator Superfamily
APDCDNMF_00150 2.5e-86 ymdB S Macro domain protein
APDCDNMF_00151 1.2e-109 K Helix-turn-helix domain
APDCDNMF_00152 0.0 pepO 3.4.24.71 O Peptidase family M13
APDCDNMF_00153 4.6e-48
APDCDNMF_00154 4.6e-233 S Putative metallopeptidase domain
APDCDNMF_00155 5.6e-206 3.1.3.1 S associated with various cellular activities
APDCDNMF_00156 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
APDCDNMF_00157 5.4e-65 yeaO S Protein of unknown function, DUF488
APDCDNMF_00159 1.2e-115 yrkL S Flavodoxin-like fold
APDCDNMF_00160 3.6e-54
APDCDNMF_00161 1.5e-18 S Domain of unknown function (DUF4767)
APDCDNMF_00162 2.9e-136 3.6.4.12 S PD-(D/E)XK nuclease family transposase
APDCDNMF_00163 3.1e-49
APDCDNMF_00164 1.6e-199 nrnB S DHHA1 domain
APDCDNMF_00165 6e-230 S Uncharacterized protein conserved in bacteria (DUF2325)
APDCDNMF_00166 2.2e-249 brnQ U Component of the transport system for branched-chain amino acids
APDCDNMF_00167 1.3e-105 NU mannosyl-glycoprotein
APDCDNMF_00168 1.6e-143 S Putative ABC-transporter type IV
APDCDNMF_00169 1.7e-274 S ABC transporter, ATP-binding protein
APDCDNMF_00170 4.1e-10
APDCDNMF_00172 5.1e-105 S Protein of unknown function (DUF3278)
APDCDNMF_00174 7e-75 M PFAM NLP P60 protein
APDCDNMF_00175 9.8e-183 ABC-SBP S ABC transporter
APDCDNMF_00176 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
APDCDNMF_00177 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
APDCDNMF_00178 8.8e-96 P Cadmium resistance transporter
APDCDNMF_00179 2.4e-56 K Transcriptional regulator, ArsR family
APDCDNMF_00180 3.2e-55 trxA O Belongs to the thioredoxin family
APDCDNMF_00181 2.3e-131 terC P membrane
APDCDNMF_00182 1.8e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APDCDNMF_00183 2.4e-167 corA P CorA-like Mg2+ transporter protein
APDCDNMF_00184 3e-23 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APDCDNMF_00185 1.5e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APDCDNMF_00186 2.6e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
APDCDNMF_00187 1.3e-142 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
APDCDNMF_00188 1.6e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
APDCDNMF_00189 2.3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
APDCDNMF_00190 8.2e-224 mdtG EGP Major facilitator Superfamily
APDCDNMF_00191 2.7e-165 T Calcineurin-like phosphoesterase superfamily domain
APDCDNMF_00192 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APDCDNMF_00194 1.4e-116 sdaAB 4.3.1.17 E Serine dehydratase beta chain
APDCDNMF_00195 7.2e-137 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
APDCDNMF_00196 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
APDCDNMF_00197 0.0 trxB2 1.8.1.9 C Thioredoxin domain
APDCDNMF_00198 0.0 M LPXTG-motif cell wall anchor domain protein
APDCDNMF_00199 9.2e-189 nss M transferase activity, transferring glycosyl groups
APDCDNMF_00200 5.5e-30 cpsJ S glycosyl transferase family 2
APDCDNMF_00201 4.2e-39 cpsJ S glycosyl transferase family 2
APDCDNMF_00202 2.5e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
APDCDNMF_00203 3.8e-287 M transferase activity, transferring glycosyl groups
APDCDNMF_00204 4.1e-286 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
APDCDNMF_00205 1.8e-164 asp3 S Accessory Sec secretory system ASP3
APDCDNMF_00206 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APDCDNMF_00207 1.7e-290 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
APDCDNMF_00208 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
APDCDNMF_00210 3.2e-305 M family 8
APDCDNMF_00211 3.9e-287 GT2,GT4 M family 8
APDCDNMF_00215 1.9e-272 pipD E Dipeptidase
APDCDNMF_00216 0.0 yjbQ P TrkA C-terminal domain protein
APDCDNMF_00217 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
APDCDNMF_00218 6.2e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APDCDNMF_00219 1.9e-81
APDCDNMF_00220 3.6e-35
APDCDNMF_00221 1.3e-102 K DNA-templated transcription, initiation
APDCDNMF_00222 8.5e-128
APDCDNMF_00223 2.2e-69 K Transcriptional regulator, HxlR family
APDCDNMF_00224 1.5e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
APDCDNMF_00225 2.7e-144 epsB M biosynthesis protein
APDCDNMF_00226 3e-120 ywqD 2.7.10.1 D Capsular exopolysaccharide family
APDCDNMF_00227 1.7e-50 pglC M Bacterial sugar transferase
APDCDNMF_00228 1.1e-87 GT4 G Glycosyl transferase 4-like
APDCDNMF_00229 1.5e-51 L hmm pf00665
APDCDNMF_00230 2e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
APDCDNMF_00231 5.7e-120 radC L DNA repair protein
APDCDNMF_00232 1.7e-179 mreB D cell shape determining protein MreB
APDCDNMF_00233 7.7e-152 mreC M Involved in formation and maintenance of cell shape
APDCDNMF_00234 3.3e-92 mreD M rod shape-determining protein MreD
APDCDNMF_00235 3.2e-102 glnP P ABC transporter permease
APDCDNMF_00236 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APDCDNMF_00237 2.6e-160 aatB ET ABC transporter substrate-binding protein
APDCDNMF_00238 6.6e-229 ymfF S Peptidase M16 inactive domain protein
APDCDNMF_00239 2.5e-247 ymfH S Peptidase M16
APDCDNMF_00240 3.1e-139 ymfM S Helix-turn-helix domain
APDCDNMF_00241 3.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APDCDNMF_00242 1.1e-228 cinA 3.5.1.42 S Belongs to the CinA family
APDCDNMF_00243 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APDCDNMF_00244 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
APDCDNMF_00245 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APDCDNMF_00246 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APDCDNMF_00247 3.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APDCDNMF_00248 4.5e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APDCDNMF_00249 6.7e-201 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
APDCDNMF_00250 6.2e-31 yajC U Preprotein translocase
APDCDNMF_00251 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
APDCDNMF_00252 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APDCDNMF_00253 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APDCDNMF_00254 4.1e-43 yrzL S Belongs to the UPF0297 family
APDCDNMF_00255 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APDCDNMF_00256 6.1e-48 yrzB S Belongs to the UPF0473 family
APDCDNMF_00257 1e-85 cvpA S Colicin V production protein
APDCDNMF_00258 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APDCDNMF_00259 6.1e-54 trxA O Belongs to the thioredoxin family
APDCDNMF_00260 5.1e-96 yslB S Protein of unknown function (DUF2507)
APDCDNMF_00261 3.2e-144 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
APDCDNMF_00262 2.4e-104 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APDCDNMF_00263 7.6e-94 S Phosphoesterase
APDCDNMF_00264 3.6e-76 ykuL S (CBS) domain
APDCDNMF_00265 1e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
APDCDNMF_00266 4e-148 ykuT M mechanosensitive ion channel
APDCDNMF_00267 1.2e-36 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APDCDNMF_00268 5.6e-08
APDCDNMF_00269 9.4e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
APDCDNMF_00270 4.5e-183 ccpA K catabolite control protein A
APDCDNMF_00271 2.5e-134
APDCDNMF_00272 1e-131 yebC K Transcriptional regulatory protein
APDCDNMF_00273 4.3e-183 comGA NU Type II IV secretion system protein
APDCDNMF_00274 1.7e-182 comGB NU type II secretion system
APDCDNMF_00275 7.9e-46 comGC U competence protein ComGC
APDCDNMF_00276 1.4e-77 NU general secretion pathway protein
APDCDNMF_00277 7.1e-41
APDCDNMF_00278 2.4e-69
APDCDNMF_00279 1.3e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
APDCDNMF_00280 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APDCDNMF_00281 5.7e-117 S Calcineurin-like phosphoesterase
APDCDNMF_00282 5.7e-100 yutD S Protein of unknown function (DUF1027)
APDCDNMF_00283 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APDCDNMF_00284 5.4e-113 S Protein of unknown function (DUF1461)
APDCDNMF_00285 1.6e-109 dedA S SNARE-like domain protein
APDCDNMF_00286 5.4e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APDCDNMF_00287 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APDCDNMF_00288 1.7e-207 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APDCDNMF_00289 3.1e-245 M Glycosyl transferase family group 2
APDCDNMF_00291 2.1e-224 aadAT EK Aminotransferase, class I
APDCDNMF_00292 1.5e-31 S Predicted membrane protein (DUF2207)
APDCDNMF_00293 6.7e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APDCDNMF_00294 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APDCDNMF_00295 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
APDCDNMF_00296 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APDCDNMF_00297 1e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APDCDNMF_00298 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APDCDNMF_00299 3.8e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
APDCDNMF_00300 2.3e-207 yacL S domain protein
APDCDNMF_00301 2.5e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APDCDNMF_00302 3.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
APDCDNMF_00303 7.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
APDCDNMF_00304 7.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
APDCDNMF_00305 9.5e-266 pepC 3.4.22.40 E Peptidase C1-like family
APDCDNMF_00306 4.3e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
APDCDNMF_00307 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APDCDNMF_00308 1.1e-119 tcyB E ABC transporter
APDCDNMF_00309 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
APDCDNMF_00310 1.1e-169 I alpha/beta hydrolase fold
APDCDNMF_00311 6e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APDCDNMF_00312 0.0 S Bacterial membrane protein, YfhO
APDCDNMF_00313 2.5e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
APDCDNMF_00314 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
APDCDNMF_00316 2.8e-84 ydcK S Belongs to the SprT family
APDCDNMF_00317 0.0 yhgF K Tex-like protein N-terminal domain protein
APDCDNMF_00318 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APDCDNMF_00319 5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APDCDNMF_00320 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
APDCDNMF_00321 1.1e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
APDCDNMF_00322 1.2e-302 aspT P Predicted Permease Membrane Region
APDCDNMF_00323 2.2e-249 EGP Major facilitator Superfamily
APDCDNMF_00324 1e-111
APDCDNMF_00327 1.8e-50 yjjH S Calcineurin-like phosphoesterase
APDCDNMF_00328 4.2e-89 yjjH S Calcineurin-like phosphoesterase
APDCDNMF_00329 1.3e-263 dtpT U amino acid peptide transporter
APDCDNMF_00330 2.4e-18
APDCDNMF_00332 1.7e-168 yqiG C Oxidoreductase
APDCDNMF_00333 4.1e-62 S macrophage migration inhibitory factor
APDCDNMF_00334 1.8e-65 K HxlR-like helix-turn-helix
APDCDNMF_00335 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APDCDNMF_00336 1.4e-58
APDCDNMF_00337 1.3e-224 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APDCDNMF_00338 5.8e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APDCDNMF_00339 3e-187 ypbB 5.1.3.1 S Helix-turn-helix domain
APDCDNMF_00340 6.2e-263 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
APDCDNMF_00341 8.5e-14 M Lysin motif
APDCDNMF_00342 3.9e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
APDCDNMF_00343 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
APDCDNMF_00344 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
APDCDNMF_00345 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APDCDNMF_00346 1.5e-236 S Tetratricopeptide repeat protein
APDCDNMF_00347 1.8e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APDCDNMF_00348 0.0 yfmR S ABC transporter, ATP-binding protein
APDCDNMF_00349 2.5e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APDCDNMF_00350 1.1e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APDCDNMF_00351 1.7e-111 hlyIII S protein, hemolysin III
APDCDNMF_00352 6.4e-151 DegV S EDD domain protein, DegV family
APDCDNMF_00353 2.6e-169 ypmR E lipolytic protein G-D-S-L family
APDCDNMF_00354 1.3e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
APDCDNMF_00355 1.7e-34 yozE S Belongs to the UPF0346 family
APDCDNMF_00356 8.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APDCDNMF_00357 7.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APDCDNMF_00358 7.8e-160 dprA LU DNA protecting protein DprA
APDCDNMF_00359 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APDCDNMF_00360 7.9e-168 lacX 5.1.3.3 G Aldose 1-epimerase
APDCDNMF_00361 9.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APDCDNMF_00362 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APDCDNMF_00363 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APDCDNMF_00364 5.4e-83 F NUDIX domain
APDCDNMF_00365 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
APDCDNMF_00366 1.1e-68 yqkB S Belongs to the HesB IscA family
APDCDNMF_00367 6e-49
APDCDNMF_00369 1.8e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
APDCDNMF_00370 1.3e-61 asp S Asp23 family, cell envelope-related function
APDCDNMF_00371 2.1e-25
APDCDNMF_00372 8.5e-96
APDCDNMF_00373 4.9e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
APDCDNMF_00374 1.2e-183 K Transcriptional regulator, LacI family
APDCDNMF_00375 2.4e-232 gntT EG Gluconate
APDCDNMF_00376 2.5e-294 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
APDCDNMF_00377 3.2e-95 K Acetyltransferase (GNAT) domain
APDCDNMF_00378 5.4e-47
APDCDNMF_00379 4.8e-23
APDCDNMF_00380 0.0 nylA 3.5.1.4 J Belongs to the amidase family
APDCDNMF_00381 5e-44
APDCDNMF_00382 3.3e-54 yhaI S Protein of unknown function (DUF805)
APDCDNMF_00383 1.6e-24
APDCDNMF_00384 1.3e-14 IQ KR domain
APDCDNMF_00385 2.6e-237 lmrB EGP Major facilitator Superfamily
APDCDNMF_00386 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
APDCDNMF_00387 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APDCDNMF_00388 1.5e-109 sufD O Uncharacterized protein family (UPF0051)
APDCDNMF_00389 6.7e-81 lytE M LysM domain protein
APDCDNMF_00390 0.0 oppD EP Psort location Cytoplasmic, score
APDCDNMF_00391 3.3e-92 lytE M LysM domain protein
APDCDNMF_00392 9.2e-149 xth 3.1.11.2 L exodeoxyribonuclease III
APDCDNMF_00393 2.1e-114 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
APDCDNMF_00394 1.7e-142 preA 1.3.1.1 C 4Fe-4S dicluster domain
APDCDNMF_00395 1.3e-151 yeaE S Aldo keto
APDCDNMF_00396 7e-77 hsp O Belongs to the small heat shock protein (HSP20) family
APDCDNMF_00397 4e-281 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
APDCDNMF_00398 4.5e-79 S Psort location Cytoplasmic, score
APDCDNMF_00399 2.9e-85 S Short repeat of unknown function (DUF308)
APDCDNMF_00400 1e-23
APDCDNMF_00401 2.8e-102 V VanZ like family
APDCDNMF_00402 1.5e-231 cycA E Amino acid permease
APDCDNMF_00403 1.6e-84 perR P Belongs to the Fur family
APDCDNMF_00404 6.7e-257 EGP Major facilitator Superfamily
APDCDNMF_00405 1.3e-93 tag 3.2.2.20 L glycosylase
APDCDNMF_00406 4.3e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APDCDNMF_00407 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
APDCDNMF_00408 4.5e-42
APDCDNMF_00409 1e-301 ytgP S Polysaccharide biosynthesis protein
APDCDNMF_00410 1.7e-28
APDCDNMF_00411 5.2e-29
APDCDNMF_00413 2e-18 K Cro/C1-type HTH DNA-binding domain
APDCDNMF_00414 7.5e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APDCDNMF_00415 2.5e-277 pepV 3.5.1.18 E dipeptidase PepV
APDCDNMF_00416 4.3e-86 uspA T Belongs to the universal stress protein A family
APDCDNMF_00417 9.2e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APDCDNMF_00418 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
APDCDNMF_00419 1.5e-112
APDCDNMF_00420 2.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
APDCDNMF_00421 2e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APDCDNMF_00422 2.1e-32
APDCDNMF_00423 7.5e-118 S CAAX protease self-immunity
APDCDNMF_00424 1.9e-43
APDCDNMF_00426 1.9e-54
APDCDNMF_00427 2.1e-143 S Domain of unknown function DUF1829
APDCDNMF_00428 1.5e-73
APDCDNMF_00429 1.1e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APDCDNMF_00430 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
APDCDNMF_00431 1.2e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
APDCDNMF_00432 2.1e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
APDCDNMF_00433 1.8e-102 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
APDCDNMF_00434 3.1e-212 folP 2.5.1.15 H dihydropteroate synthase
APDCDNMF_00435 3e-43
APDCDNMF_00436 3.3e-40
APDCDNMF_00438 5.4e-78 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APDCDNMF_00439 7.6e-51 L hmm pf00665
APDCDNMF_00440 5.6e-98 ywlG S Belongs to the UPF0340 family
APDCDNMF_00441 4.3e-198 EGP Major facilitator Superfamily
APDCDNMF_00442 2.8e-111 M Lysin motif
APDCDNMF_00443 1.6e-79
APDCDNMF_00444 9.6e-62 P CorA-like Mg2+ transporter protein
APDCDNMF_00445 5.6e-77 P CorA-like Mg2+ transporter protein
APDCDNMF_00446 5.6e-97 wecD3 K PFAM GCN5-related N-acetyltransferase
APDCDNMF_00447 1.1e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
APDCDNMF_00448 4.3e-13
APDCDNMF_00449 5.5e-77 S Domain of unknown function (DUF4767)
APDCDNMF_00450 9.7e-197 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
APDCDNMF_00451 1.3e-113 S Membrane
APDCDNMF_00452 3.9e-122 O Zinc-dependent metalloprotease
APDCDNMF_00453 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APDCDNMF_00454 2.3e-159 metQ_4 P Belongs to the nlpA lipoprotein family
APDCDNMF_00456 0.0 UW LPXTG-motif cell wall anchor domain protein
APDCDNMF_00457 0.0 UW LPXTG-motif cell wall anchor domain protein
APDCDNMF_00458 3.1e-33 L PFAM Integrase catalytic region
APDCDNMF_00459 1.5e-48
APDCDNMF_00461 5e-39 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APDCDNMF_00462 1.1e-56 K transcriptional regulator PadR family
APDCDNMF_00463 4.9e-84 XK27_06920 S Protein of unknown function (DUF1700)
APDCDNMF_00464 1.8e-136 S Putative adhesin
APDCDNMF_00465 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
APDCDNMF_00466 1.3e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APDCDNMF_00467 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APDCDNMF_00468 3.4e-35 nrdH O Glutaredoxin
APDCDNMF_00469 2.7e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APDCDNMF_00470 4.6e-287 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APDCDNMF_00471 4.6e-46 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APDCDNMF_00472 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APDCDNMF_00473 9.7e-39 S Protein of unknown function (DUF2508)
APDCDNMF_00474 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APDCDNMF_00475 7.6e-52 yaaQ S Cyclic-di-AMP receptor
APDCDNMF_00476 1.8e-184 holB 2.7.7.7 L DNA polymerase III
APDCDNMF_00477 1.7e-57 yabA L Involved in initiation control of chromosome replication
APDCDNMF_00478 3.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APDCDNMF_00479 8.1e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
APDCDNMF_00480 3.4e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
APDCDNMF_00481 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
APDCDNMF_00482 1.3e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
APDCDNMF_00483 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
APDCDNMF_00484 3.6e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
APDCDNMF_00485 4.7e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
APDCDNMF_00486 8e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APDCDNMF_00487 3.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APDCDNMF_00488 7.6e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APDCDNMF_00489 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APDCDNMF_00490 3.3e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
APDCDNMF_00491 6.9e-228 mtnE 2.6.1.83 E Aminotransferase
APDCDNMF_00492 6.2e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APDCDNMF_00493 1.2e-309 uup S ABC transporter, ATP-binding protein
APDCDNMF_00494 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APDCDNMF_00496 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APDCDNMF_00497 1.8e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APDCDNMF_00498 1.1e-32 S YbaK proline--tRNA ligase associated domain protein
APDCDNMF_00499 4.1e-33 S Aminoacyl-tRNA editing domain
APDCDNMF_00500 2.4e-303 ybeC E amino acid
APDCDNMF_00501 0.0 ydaO E amino acid
APDCDNMF_00502 3e-38
APDCDNMF_00503 6.3e-51 rmaI K Transcriptional regulator
APDCDNMF_00504 1.4e-152 yaaU EGP Major facilitator Superfamily
APDCDNMF_00505 4.7e-39 EGP Major facilitator Superfamily
APDCDNMF_00506 1.5e-51 L hmm pf00665
APDCDNMF_00507 3.9e-201 xerS L Belongs to the 'phage' integrase family
APDCDNMF_00509 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APDCDNMF_00510 4.2e-77 marR K Transcriptional regulator, MarR family
APDCDNMF_00511 5.8e-81 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APDCDNMF_00512 7.8e-85 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APDCDNMF_00513 5.5e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APDCDNMF_00514 6.5e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
APDCDNMF_00515 4.6e-129 IQ reductase
APDCDNMF_00516 5.9e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APDCDNMF_00517 1e-70 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APDCDNMF_00518 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APDCDNMF_00519 2.3e-39 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
APDCDNMF_00520 3.7e-207 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
APDCDNMF_00521 2.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APDCDNMF_00522 5.7e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
APDCDNMF_00523 2e-18 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
APDCDNMF_00524 4.8e-58 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
APDCDNMF_00533 4.1e-83 L PFAM transposase IS200-family protein
APDCDNMF_00534 8.9e-54
APDCDNMF_00535 3.5e-112 frnE Q DSBA-like thioredoxin domain
APDCDNMF_00536 6.7e-164 I alpha/beta hydrolase fold
APDCDNMF_00538 1.4e-46 yrvD S Pfam:DUF1049
APDCDNMF_00539 3.1e-150 3.1.3.102, 3.1.3.104 S hydrolase
APDCDNMF_00540 3.6e-90 ntd 2.4.2.6 F Nucleoside
APDCDNMF_00541 3.4e-21
APDCDNMF_00542 1.1e-39 S Alpha/beta hydrolase of unknown function (DUF915)
APDCDNMF_00543 3.7e-91 S Alpha/beta hydrolase of unknown function (DUF915)
APDCDNMF_00544 4.7e-114 yviA S Protein of unknown function (DUF421)
APDCDNMF_00545 5.9e-71 S Protein of unknown function (DUF3290)
APDCDNMF_00546 1.3e-41 ybaN S Protein of unknown function (DUF454)
APDCDNMF_00547 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APDCDNMF_00548 1.1e-150 endA V DNA/RNA non-specific endonuclease
APDCDNMF_00549 3e-254 yifK E Amino acid permease
APDCDNMF_00551 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APDCDNMF_00552 1.2e-230 N Uncharacterized conserved protein (DUF2075)
APDCDNMF_00553 5.1e-122 S SNARE associated Golgi protein
APDCDNMF_00554 0.0 uvrA3 L excinuclease ABC, A subunit
APDCDNMF_00555 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APDCDNMF_00556 2.5e-136 S DUF218 domain
APDCDNMF_00557 0.0 ubiB S ABC1 family
APDCDNMF_00558 1.9e-245 yhdP S Transporter associated domain
APDCDNMF_00559 5e-75 copY K Copper transport repressor CopY TcrY
APDCDNMF_00560 3.3e-245 EGP Major facilitator Superfamily
APDCDNMF_00561 1.9e-72 yeaL S UPF0756 membrane protein
APDCDNMF_00562 3.3e-76 yphH S Cupin domain
APDCDNMF_00563 3.9e-63 K Transcriptional regulator
APDCDNMF_00564 1.2e-152 1.1.1.346 C Aldo keto reductase
APDCDNMF_00565 1.4e-38 gcvR T Belongs to the UPF0237 family
APDCDNMF_00566 2.6e-80 XK27_08635 S UPF0210 protein
APDCDNMF_00567 1.4e-148 XK27_08635 S UPF0210 protein
APDCDNMF_00568 1.8e-95 K Acetyltransferase (GNAT) domain
APDCDNMF_00570 1.4e-292 L Transposase IS66 family
APDCDNMF_00571 9.2e-52 XK27_01125 L PFAM IS66 Orf2 family protein
APDCDNMF_00573 7.8e-183 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
APDCDNMF_00574 2.9e-159 rrmA 2.1.1.187 H Methyltransferase
APDCDNMF_00575 5.7e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APDCDNMF_00576 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
APDCDNMF_00577 1.2e-10 S Protein of unknown function (DUF4044)
APDCDNMF_00578 5e-57
APDCDNMF_00579 1.5e-76 mraZ K Belongs to the MraZ family
APDCDNMF_00580 3.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APDCDNMF_00581 1.5e-56 ftsL D Cell division protein FtsL
APDCDNMF_00582 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
APDCDNMF_00583 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APDCDNMF_00584 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APDCDNMF_00585 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APDCDNMF_00586 5.1e-140 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APDCDNMF_00587 1.2e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APDCDNMF_00588 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APDCDNMF_00589 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APDCDNMF_00590 3.2e-40 yggT S YGGT family
APDCDNMF_00591 1.2e-140 ylmH S S4 domain protein
APDCDNMF_00592 1.9e-42 divIVA D DivIVA domain protein
APDCDNMF_00593 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APDCDNMF_00594 4.2e-32 cspA K Cold shock protein
APDCDNMF_00595 3.2e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
APDCDNMF_00597 1.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APDCDNMF_00598 2.1e-216 iscS 2.8.1.7 E Aminotransferase class V
APDCDNMF_00599 2.8e-57 XK27_04120 S Putative amino acid metabolism
APDCDNMF_00600 3.4e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APDCDNMF_00601 8.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
APDCDNMF_00602 9e-119 S Repeat protein
APDCDNMF_00603 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APDCDNMF_00604 1.2e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APDCDNMF_00605 8.6e-187 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APDCDNMF_00606 1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
APDCDNMF_00607 5e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APDCDNMF_00608 6.7e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APDCDNMF_00609 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APDCDNMF_00610 5.9e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APDCDNMF_00611 5e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APDCDNMF_00612 3.8e-218 patA 2.6.1.1 E Aminotransferase
APDCDNMF_00613 9.7e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APDCDNMF_00614 5.6e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
APDCDNMF_00615 7.7e-58
APDCDNMF_00617 1.7e-127 mltD CBM50 M NlpC P60 family protein
APDCDNMF_00618 5.7e-29
APDCDNMF_00619 6.7e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
APDCDNMF_00620 9.8e-32 ykzG S Belongs to the UPF0356 family
APDCDNMF_00621 3.6e-82
APDCDNMF_00622 3.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APDCDNMF_00623 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
APDCDNMF_00624 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
APDCDNMF_00625 2.3e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APDCDNMF_00626 5.4e-275 lpdA 1.8.1.4 C Dehydrogenase
APDCDNMF_00627 1.5e-46 yktA S Belongs to the UPF0223 family
APDCDNMF_00628 3.5e-135 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
APDCDNMF_00629 0.0 typA T GTP-binding protein TypA
APDCDNMF_00630 1.1e-223 ftsW D Belongs to the SEDS family
APDCDNMF_00631 1.1e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
APDCDNMF_00632 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
APDCDNMF_00633 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APDCDNMF_00634 7.1e-200 ylbL T Belongs to the peptidase S16 family
APDCDNMF_00635 4.6e-77 comEA L Competence protein ComEA
APDCDNMF_00636 1.2e-88 comEB 3.5.4.12 F ComE operon protein 2
APDCDNMF_00637 0.0 comEC S Competence protein ComEC
APDCDNMF_00638 2.2e-145 holA 2.7.7.7 L DNA polymerase III delta subunit
APDCDNMF_00639 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
APDCDNMF_00640 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APDCDNMF_00641 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APDCDNMF_00642 3.5e-163 S Tetratricopeptide repeat
APDCDNMF_00643 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APDCDNMF_00644 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APDCDNMF_00645 3.1e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APDCDNMF_00646 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
APDCDNMF_00647 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
APDCDNMF_00648 4.9e-08
APDCDNMF_00649 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APDCDNMF_00650 2.3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APDCDNMF_00651 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APDCDNMF_00652 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
APDCDNMF_00653 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
APDCDNMF_00654 7.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APDCDNMF_00655 2.5e-88
APDCDNMF_00656 3e-168 M MucBP domain
APDCDNMF_00658 4.9e-16
APDCDNMF_00659 4.9e-16
APDCDNMF_00662 4.1e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APDCDNMF_00663 2e-211 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
APDCDNMF_00664 3.6e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APDCDNMF_00665 6.6e-35 ynzC S UPF0291 protein
APDCDNMF_00666 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
APDCDNMF_00667 7.8e-117 plsC 2.3.1.51 I Acyltransferase
APDCDNMF_00668 7.8e-140 yabB 2.1.1.223 L Methyltransferase small domain
APDCDNMF_00669 3.9e-47 yazA L GIY-YIG catalytic domain protein
APDCDNMF_00670 2.2e-182 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APDCDNMF_00671 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
APDCDNMF_00672 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APDCDNMF_00673 1.3e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
APDCDNMF_00674 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APDCDNMF_00675 4.8e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APDCDNMF_00676 9.9e-138 cdsA 2.7.7.41 I Belongs to the CDS family
APDCDNMF_00677 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
APDCDNMF_00678 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APDCDNMF_00679 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APDCDNMF_00680 1.9e-83 rimP J Required for maturation of 30S ribosomal subunits
APDCDNMF_00681 1.2e-214 nusA K Participates in both transcription termination and antitermination
APDCDNMF_00682 2.3e-44 ylxR K Protein of unknown function (DUF448)
APDCDNMF_00683 4.5e-49 ylxQ J ribosomal protein
APDCDNMF_00684 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APDCDNMF_00685 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APDCDNMF_00686 2.6e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APDCDNMF_00687 2.2e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
APDCDNMF_00688 7.6e-64
APDCDNMF_00689 1.2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APDCDNMF_00690 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APDCDNMF_00691 0.0 dnaK O Heat shock 70 kDa protein
APDCDNMF_00692 6.8e-196 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APDCDNMF_00693 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APDCDNMF_00694 7.3e-138 IQ KR domain
APDCDNMF_00695 2.1e-154 fhaB M Rib/alpha-like repeat
APDCDNMF_00697 9.9e-130 S membrane transporter protein
APDCDNMF_00698 2.7e-216 yjeM E Amino Acid
APDCDNMF_00699 2.5e-95 S ABC-type cobalt transport system, permease component
APDCDNMF_00700 7.8e-239 cbiO1 S ABC transporter, ATP-binding protein
APDCDNMF_00701 2.3e-111 P Cobalt transport protein
APDCDNMF_00702 1.6e-52 yvlA
APDCDNMF_00703 0.0 yjcE P Sodium proton antiporter
APDCDNMF_00704 2.2e-52 ypaA S Protein of unknown function (DUF1304)
APDCDNMF_00705 4.8e-190 D Alpha beta
APDCDNMF_00706 1e-72 K Transcriptional regulator
APDCDNMF_00707 3.5e-160
APDCDNMF_00708 4e-16 1.6.5.5 C Zinc-binding dehydrogenase
APDCDNMF_00709 5.6e-75 1.6.5.5 C Zinc-binding dehydrogenase
APDCDNMF_00710 6.4e-38 1.6.5.5 C Zinc-binding dehydrogenase
APDCDNMF_00711 2.1e-255 G PTS system Galactitol-specific IIC component
APDCDNMF_00712 2.4e-212 EGP Major facilitator Superfamily
APDCDNMF_00713 8.8e-135 V ABC transporter
APDCDNMF_00714 3.3e-108
APDCDNMF_00715 5.2e-14
APDCDNMF_00716 7.1e-63
APDCDNMF_00717 8.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
APDCDNMF_00718 5.1e-81 uspA T universal stress protein
APDCDNMF_00719 0.0 tetP J elongation factor G
APDCDNMF_00720 1.4e-167 GK ROK family
APDCDNMF_00721 1.4e-240 brnQ U Component of the transport system for branched-chain amino acids
APDCDNMF_00722 9.4e-138 aroD S Serine hydrolase (FSH1)
APDCDNMF_00723 1.5e-242 yagE E amino acid
APDCDNMF_00724 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
APDCDNMF_00725 1.5e-132 gntR K UbiC transcription regulator-associated domain protein
APDCDNMF_00726 1e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APDCDNMF_00727 1.4e-283 pipD E Dipeptidase
APDCDNMF_00728 0.0 yfiC V ABC transporter
APDCDNMF_00729 1.7e-307 lmrA V ABC transporter, ATP-binding protein
APDCDNMF_00730 1.1e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APDCDNMF_00731 2.3e-63 L Helix-turn-helix domain
APDCDNMF_00732 1.4e-13 L Helix-turn-helix domain
APDCDNMF_00733 1.4e-261 nox C NADH oxidase
APDCDNMF_00734 3.3e-86 hmpT S ECF-type riboflavin transporter, S component
APDCDNMF_00735 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
APDCDNMF_00736 5.2e-47 1.14.12.17 S Cupin 2, conserved barrel domain protein
APDCDNMF_00737 1.7e-167 yvgN C Aldo keto reductase
APDCDNMF_00738 1.1e-135 puuD S peptidase C26
APDCDNMF_00739 5.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
APDCDNMF_00740 2.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
APDCDNMF_00741 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
APDCDNMF_00742 1.1e-256 malT G Major Facilitator
APDCDNMF_00743 5.7e-206 phbA 2.3.1.9 I Belongs to the thiolase family
APDCDNMF_00744 7.3e-172 malR K Transcriptional regulator, LacI family
APDCDNMF_00745 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
APDCDNMF_00746 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
APDCDNMF_00747 2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APDCDNMF_00748 8.8e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
APDCDNMF_00750 7.8e-165 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
APDCDNMF_00751 0.0 clpL O associated with various cellular activities
APDCDNMF_00752 2.7e-32
APDCDNMF_00753 1.8e-212 patA 2.6.1.1 E Aminotransferase
APDCDNMF_00754 1.2e-175 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APDCDNMF_00755 2.9e-75 osmC O OsmC-like protein
APDCDNMF_00757 1.6e-246 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
APDCDNMF_00759 1.1e-138 K LytTr DNA-binding domain
APDCDNMF_00760 1e-227 2.7.13.3 T GHKL domain
APDCDNMF_00761 1.1e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
APDCDNMF_00762 4.1e-13
APDCDNMF_00763 1.1e-151 M Glycosyl hydrolases family 25
APDCDNMF_00764 2.3e-73 S Bacteriophage holin of superfamily 6 (Holin_LLH)
APDCDNMF_00765 4.4e-55 S Bacteriophage holin family
APDCDNMF_00768 1.1e-49 S Calcineurin-like phosphoesterase
APDCDNMF_00771 0.0 M CHAP domain
APDCDNMF_00772 1.2e-168 S Phage tail protein
APDCDNMF_00773 1.2e-240 D NLP P60 protein
APDCDNMF_00774 1.5e-92 S Phage tail assembly chaperone protein, TAC
APDCDNMF_00775 9.1e-121
APDCDNMF_00776 1.2e-70
APDCDNMF_00777 1.8e-77
APDCDNMF_00778 7.9e-46
APDCDNMF_00779 1.3e-60 S Phage gp6-like head-tail connector protein
APDCDNMF_00780 5.2e-198 gpG
APDCDNMF_00781 2.1e-96 S Domain of unknown function (DUF4355)
APDCDNMF_00783 4.2e-167 S Phage Mu protein F like protein
APDCDNMF_00784 3.5e-310 S Phage portal protein, SPP1 Gp6-like
APDCDNMF_00785 2.2e-259 S Phage terminase, large subunit
APDCDNMF_00787 1.5e-109 K Belongs to the N(4) N(6)-methyltransferase family
APDCDNMF_00789 1.4e-66
APDCDNMF_00790 7.2e-121 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
APDCDNMF_00791 1.4e-83 arpU S Phage transcriptional regulator, ArpU family
APDCDNMF_00794 2.6e-16
APDCDNMF_00797 3.9e-22
APDCDNMF_00798 2.3e-81 Q DNA (cytosine-5-)-methyltransferase activity
APDCDNMF_00800 1e-54 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
APDCDNMF_00801 4e-16
APDCDNMF_00805 5.1e-27
APDCDNMF_00806 7.3e-47 ybl78 L Conserved phage C-terminus (Phg_2220_C)
APDCDNMF_00807 1.9e-149 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
APDCDNMF_00808 4e-162 recT L RecT family
APDCDNMF_00816 2.6e-13
APDCDNMF_00817 8.9e-50 ps115 K Helix-turn-helix XRE-family like proteins
APDCDNMF_00818 3.5e-20 E Zn peptidase
APDCDNMF_00819 1.1e-10
APDCDNMF_00823 2.2e-50 L hmm pf00665
APDCDNMF_00824 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APDCDNMF_00825 9.4e-38 yheA S Belongs to the UPF0342 family
APDCDNMF_00826 2.8e-213 yhaO L Ser Thr phosphatase family protein
APDCDNMF_00827 0.0 L AAA domain
APDCDNMF_00828 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APDCDNMF_00830 8.3e-78 hit FG histidine triad
APDCDNMF_00831 1e-136 ecsA V ABC transporter, ATP-binding protein
APDCDNMF_00832 1.3e-216 ecsB U ABC transporter
APDCDNMF_00833 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APDCDNMF_00834 2.9e-45 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
APDCDNMF_00835 6.9e-83 A chlorophyll binding
APDCDNMF_00836 1.8e-249 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
APDCDNMF_00837 2.2e-179 iolS C Aldo keto reductase
APDCDNMF_00838 2.6e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
APDCDNMF_00839 2e-55 ytzB S Small secreted protein
APDCDNMF_00840 6.6e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
APDCDNMF_00841 7.9e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APDCDNMF_00842 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
APDCDNMF_00843 9.3e-119 ybhL S Belongs to the BI1 family
APDCDNMF_00844 1.4e-119 yoaK S Protein of unknown function (DUF1275)
APDCDNMF_00845 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APDCDNMF_00846 1.3e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APDCDNMF_00847 1.4e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APDCDNMF_00848 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APDCDNMF_00849 2e-226 dnaB L replication initiation and membrane attachment
APDCDNMF_00850 3.3e-172 dnaI L Primosomal protein DnaI
APDCDNMF_00851 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APDCDNMF_00852 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
APDCDNMF_00853 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APDCDNMF_00854 4.1e-95 yqeG S HAD phosphatase, family IIIA
APDCDNMF_00855 1.2e-216 yqeH S Ribosome biogenesis GTPase YqeH
APDCDNMF_00856 1.9e-47 yhbY J RNA-binding protein
APDCDNMF_00857 6.2e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APDCDNMF_00858 8.6e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
APDCDNMF_00859 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APDCDNMF_00860 4.9e-139 yqeM Q Methyltransferase
APDCDNMF_00861 6.1e-213 ylbM S Belongs to the UPF0348 family
APDCDNMF_00862 2.9e-99 yceD S Uncharacterized ACR, COG1399
APDCDNMF_00863 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
APDCDNMF_00864 1.3e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
APDCDNMF_00865 1.4e-147 3.1.3.48 T Pfam:Y_phosphatase3C
APDCDNMF_00866 5.5e-56 pduU E BMC
APDCDNMF_00867 1.4e-220 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APDCDNMF_00868 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
APDCDNMF_00869 3.1e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
APDCDNMF_00870 7.4e-80 pduO S Haem-degrading
APDCDNMF_00871 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
APDCDNMF_00872 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
APDCDNMF_00873 6.4e-90 S Putative propanediol utilisation
APDCDNMF_00874 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
APDCDNMF_00875 4.9e-42 pduA_4 CQ BMC
APDCDNMF_00876 1.4e-72 pduK CQ BMC
APDCDNMF_00877 2.5e-59 pduH S Dehydratase medium subunit
APDCDNMF_00878 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
APDCDNMF_00879 3.7e-77 pduE 4.2.1.28 Q Dehydratase small subunit
APDCDNMF_00880 4.2e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
APDCDNMF_00881 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
APDCDNMF_00882 2.7e-134 pduB E BMC
APDCDNMF_00883 6.2e-42 pduA_4 CQ BMC
APDCDNMF_00884 3.4e-197 K helix_turn_helix, arabinose operon control protein
APDCDNMF_00885 7.8e-149 eutJ E Hsp70 protein
APDCDNMF_00886 1.2e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
APDCDNMF_00887 2.1e-163
APDCDNMF_00888 2.4e-158 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
APDCDNMF_00889 8.7e-172 S AI-2E family transporter
APDCDNMF_00890 8.9e-133 XK27_07210 6.1.1.6 S B3 4 domain
APDCDNMF_00891 2.5e-77 yybA 2.3.1.57 K Transcriptional regulator
APDCDNMF_00892 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
APDCDNMF_00893 1.8e-90 GM epimerase
APDCDNMF_00894 6.3e-154 ypdB V (ABC) transporter
APDCDNMF_00895 1.6e-241 yhdP S Transporter associated domain
APDCDNMF_00896 1.3e-84 nrdI F Belongs to the NrdI family
APDCDNMF_00897 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
APDCDNMF_00898 9.8e-192 yeaN P Transporter, major facilitator family protein
APDCDNMF_00899 2.9e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APDCDNMF_00900 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APDCDNMF_00901 2e-33
APDCDNMF_00902 0.0 lacS G Transporter
APDCDNMF_00904 1.7e-173 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
APDCDNMF_00905 8.2e-58 hol S COG5546 Small integral membrane protein
APDCDNMF_00906 2.3e-27
APDCDNMF_00910 9.4e-163
APDCDNMF_00911 6.8e-23 S GDSL-like Lipase/Acylhydrolase
APDCDNMF_00914 2.8e-14 tcdA2 GT2,GT4 LM gp58-like protein
APDCDNMF_00915 1.8e-201 M Prophage endopeptidase tail
APDCDNMF_00916 3.1e-113 S Phage tail protein
APDCDNMF_00917 5.8e-224 M Phage tail tape measure protein TP901
APDCDNMF_00918 1.6e-19
APDCDNMF_00919 1.2e-65 S Phage tail tube protein
APDCDNMF_00920 5.7e-25
APDCDNMF_00921 1.3e-20
APDCDNMF_00922 4e-38 S Phage head-tail joining protein
APDCDNMF_00923 1.8e-43 S Phage gp6-like head-tail connector protein
APDCDNMF_00924 1.5e-131 S Phage capsid family
APDCDNMF_00925 1.7e-88 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
APDCDNMF_00926 4.9e-145 S portal protein
APDCDNMF_00928 1.4e-267 S Phage Terminase
APDCDNMF_00929 4.2e-80 L Phage terminase, small subunit
APDCDNMF_00930 4.3e-50 L HNH nucleases
APDCDNMF_00943 3.5e-56 padR K Virulence activator alpha C-term
APDCDNMF_00944 1.4e-165 ypuA S Protein of unknown function (DUF1002)
APDCDNMF_00945 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
APDCDNMF_00946 7.8e-152 K Transcriptional regulator
APDCDNMF_00947 9.6e-158 akr5f 1.1.1.346 S reductase
APDCDNMF_00948 2.4e-62 yneR
APDCDNMF_00949 5e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
APDCDNMF_00950 1.4e-17
APDCDNMF_00951 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
APDCDNMF_00952 1.4e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
APDCDNMF_00953 1.3e-29 yjaB_1 K Acetyltransferase (GNAT) domain
APDCDNMF_00954 1.3e-88 folT S ECF transporter, substrate-specific component
APDCDNMF_00955 0.0 pepN 3.4.11.2 E aminopeptidase
APDCDNMF_00956 3.4e-112 ylbE GM NAD dependent epimerase dehydratase family protein
APDCDNMF_00957 5.4e-253 pepC 3.4.22.40 E aminopeptidase
APDCDNMF_00958 1.3e-205 EGP Major facilitator Superfamily
APDCDNMF_00959 1.7e-227
APDCDNMF_00960 7.1e-80 K Transcriptional regulator, HxlR family
APDCDNMF_00961 4.5e-106 XK27_02070 S Nitroreductase family
APDCDNMF_00962 8.1e-51 hxlR K Transcriptional regulator, HxlR family
APDCDNMF_00963 3e-10 GM NmrA-like family
APDCDNMF_00964 3.6e-73 elaA S Gnat family
APDCDNMF_00965 2.7e-38 S Cytochrome B5
APDCDNMF_00966 5.4e-09 S Cytochrome B5
APDCDNMF_00967 1.7e-40 S Cytochrome B5
APDCDNMF_00968 8.8e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
APDCDNMF_00970 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APDCDNMF_00971 4.1e-240 E amino acid
APDCDNMF_00972 2.9e-251 npp S type I phosphodiesterase nucleotide pyrophosphatase
APDCDNMF_00973 8.1e-20 yxiO S Vacuole effluxer Atg22 like
APDCDNMF_00974 2.3e-117 yxiO S Vacuole effluxer Atg22 like
APDCDNMF_00975 2.3e-32 yxiO S Vacuole effluxer Atg22 like
APDCDNMF_00977 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APDCDNMF_00978 1.6e-22
APDCDNMF_00979 3e-290 mntH P H( )-stimulated, divalent metal cation uptake system
APDCDNMF_00980 7.2e-09
APDCDNMF_00981 2.5e-155 P Belongs to the nlpA lipoprotein family
APDCDNMF_00982 3.9e-12
APDCDNMF_00983 1.4e-223 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
APDCDNMF_00984 1.3e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APDCDNMF_00985 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
APDCDNMF_00986 1.6e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APDCDNMF_00987 3.8e-21 S Protein of unknown function (DUF3042)
APDCDNMF_00988 2.6e-67 yqhL P Rhodanese-like protein
APDCDNMF_00989 9.6e-183 glk 2.7.1.2 G Glucokinase
APDCDNMF_00990 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
APDCDNMF_00991 1.6e-112 gluP 3.4.21.105 S Peptidase, S54 family
APDCDNMF_00992 1.3e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APDCDNMF_00993 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
APDCDNMF_00994 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
APDCDNMF_00995 0.0 S membrane
APDCDNMF_00996 1.3e-69 yneR S Belongs to the HesB IscA family
APDCDNMF_00997 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APDCDNMF_00998 7.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
APDCDNMF_00999 1.2e-114 rlpA M PFAM NLP P60 protein
APDCDNMF_01000 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APDCDNMF_01001 1.5e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APDCDNMF_01002 6.7e-59 yodB K Transcriptional regulator, HxlR family
APDCDNMF_01003 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
APDCDNMF_01004 4.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APDCDNMF_01005 3.2e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
APDCDNMF_01006 2.6e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APDCDNMF_01007 1.8e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
APDCDNMF_01008 1.5e-231 V MatE
APDCDNMF_01009 1.9e-267 yjeM E Amino Acid
APDCDNMF_01010 3.1e-278 arlS 2.7.13.3 T Histidine kinase
APDCDNMF_01011 1.5e-121 K response regulator
APDCDNMF_01014 1.3e-35 S Bacteriophage holin family
APDCDNMF_01015 4.7e-57 S Bacteriophage holin of superfamily 6 (Holin_LLH)
APDCDNMF_01016 4.4e-200 3.5.1.104 M hydrolase, family 25
APDCDNMF_01017 1.2e-33 S Bacteriophage abortive infection AbiH
APDCDNMF_01018 2.3e-30 S Protein of unknown function (DUF2929)
APDCDNMF_01019 0.0 dnaE 2.7.7.7 L DNA polymerase
APDCDNMF_01020 8e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
APDCDNMF_01021 3e-167 cvfB S S1 domain
APDCDNMF_01022 3.5e-163 xerD D recombinase XerD
APDCDNMF_01023 1.6e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APDCDNMF_01024 4.8e-140 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APDCDNMF_01025 1.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APDCDNMF_01026 2.6e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APDCDNMF_01027 1.6e-70 L Belongs to the 'phage' integrase family
APDCDNMF_01028 9.3e-26
APDCDNMF_01031 8.1e-76 E IrrE N-terminal-like domain
APDCDNMF_01032 1.4e-48 K Cro/C1-type HTH DNA-binding domain
APDCDNMF_01033 1.3e-20
APDCDNMF_01034 9.6e-111 S Protein of unknown function (DUF3102)
APDCDNMF_01036 5.4e-08
APDCDNMF_01040 3.8e-07
APDCDNMF_01042 1.7e-54 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APDCDNMF_01043 4.6e-131 S Putative HNHc nuclease
APDCDNMF_01044 1e-34 L Psort location Cytoplasmic, score
APDCDNMF_01048 3.7e-36
APDCDNMF_01049 2.7e-31
APDCDNMF_01050 3.4e-74 rusA L Endodeoxyribonuclease RusA
APDCDNMF_01058 1.6e-162
APDCDNMF_01059 2.3e-122 dck 2.7.1.74 F deoxynucleoside kinase
APDCDNMF_01064 2.5e-74 S Transcriptional regulator, RinA family
APDCDNMF_01066 2.5e-256 E Arginine ornithine antiporter
APDCDNMF_01067 1.3e-220 arcT 2.6.1.1 E Aminotransferase
APDCDNMF_01068 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
APDCDNMF_01069 3.9e-78 fld C Flavodoxin
APDCDNMF_01070 2.3e-67 gtcA S Teichoic acid glycosylation protein
APDCDNMF_01071 2.1e-55
APDCDNMF_01072 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APDCDNMF_01074 2.5e-231 yfmL L DEAD DEAH box helicase
APDCDNMF_01075 1.3e-190 mocA S Oxidoreductase
APDCDNMF_01076 9.1e-62 S Domain of unknown function (DUF4828)
APDCDNMF_01077 2e-103 yvdD 3.2.2.10 S Belongs to the LOG family
APDCDNMF_01078 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
APDCDNMF_01079 2.1e-293 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
APDCDNMF_01080 1.7e-190 S Protein of unknown function (DUF3114)
APDCDNMF_01081 5e-73 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
APDCDNMF_01082 5.4e-119 ybhL S Belongs to the BI1 family
APDCDNMF_01083 5.5e-21
APDCDNMF_01084 5.2e-72 K LytTr DNA-binding domain
APDCDNMF_01085 1.2e-68 S Protein of unknown function (DUF3021)
APDCDNMF_01086 8.4e-136 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
APDCDNMF_01087 1.5e-22 XK27_00915 C Luciferase-like monooxygenase
APDCDNMF_01088 5.4e-121 pnb C nitroreductase
APDCDNMF_01089 2.9e-88
APDCDNMF_01090 2.3e-243 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
APDCDNMF_01091 1.1e-38 amtB P ammonium transporter
APDCDNMF_01092 7.6e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
APDCDNMF_01094 1.1e-47
APDCDNMF_01095 1.1e-153 cylA V ABC transporter
APDCDNMF_01096 4.5e-144 cylB V ABC-2 type transporter
APDCDNMF_01097 7.6e-74 K LytTr DNA-binding domain
APDCDNMF_01098 1.8e-60 S Protein of unknown function (DUF3021)
APDCDNMF_01100 2.2e-176 L Plasmid pRiA4b ORF-3-like protein
APDCDNMF_01101 2e-71 1.6.5.2 S NADPH-dependent FMN reductase
APDCDNMF_01102 1.3e-85 K Bacterial regulatory proteins, tetR family
APDCDNMF_01103 7.1e-127 L Helix-turn-helix domain
APDCDNMF_01104 4.5e-230 ndh 1.6.99.3 C NADH dehydrogenase
APDCDNMF_01105 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
APDCDNMF_01106 1.7e-307 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
APDCDNMF_01107 1.4e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
APDCDNMF_01108 7.2e-272 cydA 1.10.3.14 C ubiquinol oxidase
APDCDNMF_01109 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APDCDNMF_01110 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APDCDNMF_01111 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
APDCDNMF_01112 5.8e-252 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APDCDNMF_01113 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APDCDNMF_01114 0.0 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
APDCDNMF_01115 3.1e-206 E Amino acid permease
APDCDNMF_01116 4.1e-242 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
APDCDNMF_01117 1.3e-233 pbuG S permease
APDCDNMF_01118 4.1e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
APDCDNMF_01119 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
APDCDNMF_01120 3e-136 S Belongs to the UPF0246 family
APDCDNMF_01121 1.2e-137 S Membrane
APDCDNMF_01122 8.1e-75 4.4.1.5 E Glyoxalase
APDCDNMF_01123 1.2e-21
APDCDNMF_01124 2.5e-86 yueI S Protein of unknown function (DUF1694)
APDCDNMF_01125 4.6e-241 rarA L recombination factor protein RarA
APDCDNMF_01126 5.7e-46
APDCDNMF_01127 4.3e-83 usp6 T universal stress protein
APDCDNMF_01128 5.9e-205 araR K Transcriptional regulator
APDCDNMF_01129 2.3e-156 ytbE 1.1.1.346 S Aldo keto reductase
APDCDNMF_01130 3.2e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
APDCDNMF_01131 2.4e-283 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
APDCDNMF_01132 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
APDCDNMF_01133 0.0 araB 2.7.1.16 G carbohydrate kinase FGGY
APDCDNMF_01134 7.5e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APDCDNMF_01135 9.6e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
APDCDNMF_01136 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
APDCDNMF_01137 1.8e-47 gcvH E glycine cleavage
APDCDNMF_01138 3.2e-220 rodA D Belongs to the SEDS family
APDCDNMF_01139 1e-31 S Protein of unknown function (DUF2969)
APDCDNMF_01140 5.5e-178 mbl D Cell shape determining protein MreB Mrl
APDCDNMF_01141 2.5e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APDCDNMF_01142 2.2e-33 ywzB S Protein of unknown function (DUF1146)
APDCDNMF_01143 5.9e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
APDCDNMF_01144 5.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APDCDNMF_01145 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APDCDNMF_01146 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APDCDNMF_01147 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APDCDNMF_01148 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APDCDNMF_01149 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APDCDNMF_01150 4.7e-123 atpB C it plays a direct role in the translocation of protons across the membrane
APDCDNMF_01151 6.5e-232 pyrP F Permease
APDCDNMF_01152 7e-128 yibF S overlaps another CDS with the same product name
APDCDNMF_01153 1.3e-191 yibE S overlaps another CDS with the same product name
APDCDNMF_01154 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APDCDNMF_01155 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APDCDNMF_01156 3.5e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APDCDNMF_01157 1.4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APDCDNMF_01158 6.8e-164 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APDCDNMF_01159 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APDCDNMF_01160 6e-108 tdk 2.7.1.21 F thymidine kinase
APDCDNMF_01161 1.7e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
APDCDNMF_01162 1.2e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
APDCDNMF_01164 6.7e-222 arcD U Amino acid permease
APDCDNMF_01165 1.5e-261 E Arginine ornithine antiporter
APDCDNMF_01166 2.7e-79 argR K Regulates arginine biosynthesis genes
APDCDNMF_01167 9.1e-239 arcA 3.5.3.6 E Arginine
APDCDNMF_01168 5.7e-186 ampC V Beta-lactamase
APDCDNMF_01169 1.2e-18
APDCDNMF_01170 0.0 M domain protein
APDCDNMF_01171 2.2e-90
APDCDNMF_01173 2.2e-38 yjcE P Sodium proton antiporter
APDCDNMF_01174 8.5e-150 yjcE P Sodium proton antiporter
APDCDNMF_01175 3.6e-57
APDCDNMF_01177 1.7e-87
APDCDNMF_01178 0.0 copA 3.6.3.54 P P-type ATPase
APDCDNMF_01179 8.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
APDCDNMF_01180 5.6e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
APDCDNMF_01181 1.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
APDCDNMF_01182 3.9e-162 EG EamA-like transporter family
APDCDNMF_01183 2.1e-171 arcC 2.7.2.2 E Belongs to the carbamate kinase family
APDCDNMF_01184 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APDCDNMF_01185 1.2e-154 KT YcbB domain
APDCDNMF_01186 3.3e-299 xylB 2.7.1.17 G Belongs to the FGGY kinase family
APDCDNMF_01187 1.3e-270 xylA 5.3.1.5 G Belongs to the xylose isomerase family
APDCDNMF_01188 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
APDCDNMF_01189 6e-20 pgdA 3.5.1.104 G polysaccharide deacetylase
APDCDNMF_01190 0.0 3.2.1.55 GH51 G Right handed beta helix region
APDCDNMF_01191 6.9e-289 xynT G MFS/sugar transport protein
APDCDNMF_01192 1.9e-172 rhaS2 K Transcriptional regulator, AraC family
APDCDNMF_01193 6.2e-260 xylT EGP Major facilitator Superfamily
APDCDNMF_01195 3e-215 xylR GK ROK family
APDCDNMF_01196 8.5e-28
APDCDNMF_01197 3.4e-263 pgi 5.3.1.9 G Belongs to the GPI family
APDCDNMF_01198 4.4e-101 lacA 2.3.1.79 S Transferase hexapeptide repeat
APDCDNMF_01199 2.6e-155 glcU U sugar transport
APDCDNMF_01200 2.7e-269 yclK 2.7.13.3 T Histidine kinase
APDCDNMF_01201 4.4e-132 K response regulator
APDCDNMF_01203 5.3e-78 lytE M Lysin motif
APDCDNMF_01204 2.8e-143 XK27_02985 S Cof-like hydrolase
APDCDNMF_01205 2.3e-81 K Transcriptional regulator
APDCDNMF_01206 0.0 oatA I Acyltransferase
APDCDNMF_01207 8.7e-53
APDCDNMF_01208 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APDCDNMF_01209 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APDCDNMF_01210 1.1e-124 ybbR S YbbR-like protein
APDCDNMF_01211 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APDCDNMF_01212 1.5e-51 L hmm pf00665
APDCDNMF_01213 4.1e-54 L Transposase, IS116 IS110 IS902 family
APDCDNMF_01215 1.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APDCDNMF_01216 1.2e-266 yfnA E amino acid
APDCDNMF_01217 3.5e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APDCDNMF_01218 4.1e-41 1.3.5.4 S FMN binding
APDCDNMF_01219 4.9e-221 norA EGP Major facilitator Superfamily
APDCDNMF_01220 2e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
APDCDNMF_01221 6.7e-156 metQ1 P Belongs to the nlpA lipoprotein family
APDCDNMF_01222 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APDCDNMF_01223 3.1e-103 metI P ABC transporter permease
APDCDNMF_01224 8.3e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
APDCDNMF_01225 2.2e-28 clcA P chloride
APDCDNMF_01226 1.4e-117 clcA P chloride
APDCDNMF_01227 2.8e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
APDCDNMF_01228 2.3e-100 proW P ABC transporter, permease protein
APDCDNMF_01229 9.4e-141 proV E ABC transporter, ATP-binding protein
APDCDNMF_01230 8.2e-109 proWZ P ABC transporter permease
APDCDNMF_01231 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
APDCDNMF_01232 1.4e-72 K Transcriptional regulator
APDCDNMF_01233 4.7e-208 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
APDCDNMF_01234 0.0 cadA P P-type ATPase
APDCDNMF_01235 2.4e-109 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
APDCDNMF_01236 2.1e-126
APDCDNMF_01237 2.8e-54 S Sugar efflux transporter for intercellular exchange
APDCDNMF_01238 4.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
APDCDNMF_01240 0.0 L Helicase C-terminal domain protein
APDCDNMF_01241 3.4e-83 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
APDCDNMF_01242 1.1e-180 S Aldo keto reductase
APDCDNMF_01243 3.4e-81 S ECF transporter, substrate-specific component
APDCDNMF_01244 9.6e-62 S Domain of unknown function (DUF4430)
APDCDNMF_01245 2.2e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
APDCDNMF_01246 5.3e-130 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
APDCDNMF_01247 7e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
APDCDNMF_01248 9.9e-135 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
APDCDNMF_01249 7.8e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
APDCDNMF_01250 1.4e-250 hemL 5.4.3.8 H Aminotransferase class-III
APDCDNMF_01251 3.8e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
APDCDNMF_01252 2.9e-165 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
APDCDNMF_01253 4.4e-228 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
APDCDNMF_01254 6.7e-78 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
APDCDNMF_01255 1.8e-276 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
APDCDNMF_01256 2.8e-148 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
APDCDNMF_01257 4.4e-118 cbiQ P Cobalt transport protein
APDCDNMF_01258 8.7e-53 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
APDCDNMF_01259 5.3e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
APDCDNMF_01260 2.1e-123 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
APDCDNMF_01261 1.8e-144 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
APDCDNMF_01262 3.4e-258 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
APDCDNMF_01263 6.4e-134 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
APDCDNMF_01264 1.8e-130 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
APDCDNMF_01265 5.5e-192 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
APDCDNMF_01266 1.2e-132 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
APDCDNMF_01267 1.7e-96 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
APDCDNMF_01268 9.7e-109 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
APDCDNMF_01269 1.5e-206 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
APDCDNMF_01270 2.7e-123 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
APDCDNMF_01271 1.7e-179 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
APDCDNMF_01272 1.5e-261 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
APDCDNMF_01273 3.7e-207 cobD 4.1.1.81 E Aminotransferase class I and II
APDCDNMF_01274 6.3e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
APDCDNMF_01275 7.3e-155 XK27_04590 S NADPH-dependent FMN reductase
APDCDNMF_01276 3.9e-78 fld C Flavodoxin
APDCDNMF_01277 8.8e-72 eutP E Ethanolamine utilisation - propanediol utilisation
APDCDNMF_01278 3.1e-33 L PFAM Integrase catalytic region
APDCDNMF_01279 3.7e-52 P Belongs to the ABC transporter superfamily
APDCDNMF_01280 1.3e-55 EP N-terminal TM domain of oligopeptide transport permease C
APDCDNMF_01281 1e-48 nikB P Binding-protein-dependent transport system inner membrane component
APDCDNMF_01282 3.7e-152 nikA E Bacterial extracellular solute-binding proteins, family 5 Middle
APDCDNMF_01283 1.3e-57 ubiE_1 Q Methyltransferase
APDCDNMF_01284 9.2e-253 ytjP 3.5.1.18 E Dipeptidase
APDCDNMF_01285 3.8e-271 arcD S C4-dicarboxylate anaerobic carrier
APDCDNMF_01286 6.7e-173 yfeX P Peroxidase
APDCDNMF_01287 2.4e-126 lsa S ABC transporter
APDCDNMF_01288 5.5e-111 I alpha/beta hydrolase fold
APDCDNMF_01289 1.5e-166 L transposase, IS605 OrfB family
APDCDNMF_01290 1.2e-172 MA20_14895 S Conserved hypothetical protein 698
APDCDNMF_01291 1.5e-84 S NADPH-dependent FMN reductase
APDCDNMF_01292 5.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APDCDNMF_01293 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
APDCDNMF_01294 2.6e-231 mntH P H( )-stimulated, divalent metal cation uptake system
APDCDNMF_01295 6.5e-80 Q Methyltransferase
APDCDNMF_01296 6.9e-116 ktrA P domain protein
APDCDNMF_01297 5.8e-239 ktrB P Potassium uptake protein
APDCDNMF_01298 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
APDCDNMF_01299 7.8e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
APDCDNMF_01300 2.2e-223 G Glycosyl hydrolases family 8
APDCDNMF_01301 3.2e-242 ydaM M Glycosyl transferase
APDCDNMF_01302 2.5e-134
APDCDNMF_01303 7.8e-76
APDCDNMF_01304 9.8e-180
APDCDNMF_01305 2.9e-182 fecB P Periplasmic binding protein
APDCDNMF_01306 1.2e-138 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
APDCDNMF_01307 8.3e-131 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APDCDNMF_01308 7.8e-79 S Flavodoxin
APDCDNMF_01309 2.2e-64 moaE 2.8.1.12 H MoaE protein
APDCDNMF_01310 6.4e-35 moaD 2.8.1.12 H ThiS family
APDCDNMF_01311 7.8e-219 narK P Transporter, major facilitator family protein
APDCDNMF_01312 8.4e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
APDCDNMF_01313 1.2e-180
APDCDNMF_01314 1.6e-18
APDCDNMF_01315 2.3e-116 nreC K PFAM regulatory protein LuxR
APDCDNMF_01316 7.4e-189 comP 2.7.13.3 F Sensor histidine kinase
APDCDNMF_01317 8.8e-44
APDCDNMF_01318 1.2e-103 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
APDCDNMF_01319 9.7e-83 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
APDCDNMF_01320 7.9e-227 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
APDCDNMF_01321 9.2e-81 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
APDCDNMF_01322 7.2e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
APDCDNMF_01323 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APDCDNMF_01324 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
APDCDNMF_01325 2.3e-99 narJ C nitrate reductase molybdenum cofactor assembly chaperone
APDCDNMF_01326 1.9e-129 narI 1.7.5.1 C Nitrate reductase
APDCDNMF_01327 2.7e-152 EG EamA-like transporter family
APDCDNMF_01328 7.2e-118 L Integrase
APDCDNMF_01329 1.1e-158 rssA S Phospholipase, patatin family
APDCDNMF_01331 9e-199 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
APDCDNMF_01332 3.3e-47 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
APDCDNMF_01333 2.1e-123 phoU P Plays a role in the regulation of phosphate uptake
APDCDNMF_01334 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APDCDNMF_01335 3.2e-153 pstA P Phosphate transport system permease protein PstA
APDCDNMF_01336 4.7e-152 pstC P probably responsible for the translocation of the substrate across the membrane
APDCDNMF_01337 9.6e-158 pstS P Phosphate
APDCDNMF_01338 6.6e-133 K Transcriptional regulatory protein, C-terminal domain protein
APDCDNMF_01339 8.6e-136 cbiO P ABC transporter
APDCDNMF_01340 2.1e-133 P Cobalt transport protein
APDCDNMF_01341 1e-182 nikMN P PDGLE domain
APDCDNMF_01342 1.3e-72 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APDCDNMF_01343 5.5e-41 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APDCDNMF_01344 2.4e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
APDCDNMF_01345 2.1e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
APDCDNMF_01346 6.9e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
APDCDNMF_01347 3.3e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
APDCDNMF_01348 0.0 ureC 3.5.1.5 E Amidohydrolase family
APDCDNMF_01349 7.7e-64 ureB 3.5.1.5 E Urease beta subunit
APDCDNMF_01350 2.9e-45 ureA 3.5.1.5 E Urease, gamma subunit
APDCDNMF_01351 4.4e-94 ureI S AmiS/UreI family transporter
APDCDNMF_01352 2.1e-216 P ammonium transporter
APDCDNMF_01353 1.2e-14 K Transcriptional regulator, HxlR family
APDCDNMF_01354 1.6e-167
APDCDNMF_01355 3.7e-96 2.3.1.128 K acetyltransferase
APDCDNMF_01356 6.6e-23 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APDCDNMF_01357 3.5e-15 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APDCDNMF_01359 2.1e-95
APDCDNMF_01360 2.8e-60
APDCDNMF_01361 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APDCDNMF_01362 4.9e-183 S Phosphotransferase system, EIIC
APDCDNMF_01363 2.1e-48 UW LPXTG-motif cell wall anchor domain protein
APDCDNMF_01364 2.8e-13
APDCDNMF_01367 1.1e-23 E Zn peptidase
APDCDNMF_01368 1.7e-15 K Helix-turn-helix domain
APDCDNMF_01369 3e-23
APDCDNMF_01370 2.9e-19
APDCDNMF_01371 1.2e-32 S Domain of unknown function (DUF4417)
APDCDNMF_01372 3.6e-260 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APDCDNMF_01373 5.3e-184 yegS 2.7.1.107 G Lipid kinase
APDCDNMF_01374 2.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APDCDNMF_01375 6.5e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APDCDNMF_01376 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APDCDNMF_01377 3.6e-202 camS S sex pheromone
APDCDNMF_01378 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APDCDNMF_01379 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
APDCDNMF_01380 2.3e-212 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
APDCDNMF_01381 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APDCDNMF_01382 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
APDCDNMF_01383 9.4e-141 IQ reductase
APDCDNMF_01386 7.4e-83 S GIY-YIG catalytic domain
APDCDNMF_01387 4.4e-118 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
APDCDNMF_01388 5e-249 mmuP E amino acid
APDCDNMF_01391 0.0 snf 2.7.11.1 KL domain protein
APDCDNMF_01392 9.1e-144 ywqE 3.1.3.48 GM PHP domain protein
APDCDNMF_01393 7.9e-19 M Glycosyl hydrolases family 25
APDCDNMF_01394 3.4e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
APDCDNMF_01395 0.0 sbcC L Putative exonuclease SbcCD, C subunit
APDCDNMF_01396 2.8e-96 L nuclease
APDCDNMF_01397 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
APDCDNMF_01398 3.3e-71
APDCDNMF_01399 1.7e-102 fic D Fic/DOC family
APDCDNMF_01400 8.3e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APDCDNMF_01401 1.9e-150 3.1.3.73 G Belongs to the phosphoglycerate mutase family
APDCDNMF_01402 5.7e-19
APDCDNMF_01403 6.4e-42
APDCDNMF_01404 3.7e-97
APDCDNMF_01405 4.6e-24
APDCDNMF_01406 2e-35 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
APDCDNMF_01408 7.2e-116 azlC E azaleucine resistance protein AzlC
APDCDNMF_01409 3e-48 azlD E Branched-chain amino acid transport
APDCDNMF_01410 8.3e-114 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
APDCDNMF_01412 7.2e-29 S GyrI-like small molecule binding domain
APDCDNMF_01413 3.7e-47 S GyrI-like small molecule binding domain
APDCDNMF_01414 8e-120 yhiD S MgtC family
APDCDNMF_01415 6.2e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
APDCDNMF_01416 5.3e-192 V Beta-lactamase
APDCDNMF_01417 5.3e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APDCDNMF_01418 4.5e-88 XK27_08850 J Aminoacyl-tRNA editing domain
APDCDNMF_01419 3e-20 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
APDCDNMF_01420 8.6e-118 K LytTr DNA-binding domain
APDCDNMF_01421 2.6e-196 2.7.13.3 T GHKL domain
APDCDNMF_01425 2.1e-43 mleP3 S Membrane transport protein
APDCDNMF_01426 1e-122 T Transcriptional regulatory protein, C terminal
APDCDNMF_01427 1.5e-239 T GHKL domain
APDCDNMF_01428 3e-108 S Peptidase propeptide and YPEB domain
APDCDNMF_01429 1.8e-115 P nitric oxide dioxygenase activity
APDCDNMF_01430 2.4e-10 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
APDCDNMF_01431 2.8e-54 yphJ 4.1.1.44 S decarboxylase
APDCDNMF_01432 1.3e-31 S Oxidoreductase, aldo keto reductase family protein
APDCDNMF_01433 4.1e-110 S Oxidoreductase, aldo keto reductase family protein
APDCDNMF_01434 7.4e-71 C Flavodoxin
APDCDNMF_01435 7.5e-92 padC Q Phenolic acid decarboxylase
APDCDNMF_01436 4e-41 L Belongs to the 'phage' integrase family
APDCDNMF_01437 5.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
APDCDNMF_01438 1.4e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APDCDNMF_01439 3.8e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
APDCDNMF_01440 7e-220 patA 2.6.1.1 E Aminotransferase
APDCDNMF_01441 6.5e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APDCDNMF_01442 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APDCDNMF_01443 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
APDCDNMF_01444 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
APDCDNMF_01445 1.8e-147 recO L Involved in DNA repair and RecF pathway recombination
APDCDNMF_01446 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APDCDNMF_01447 1.9e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
APDCDNMF_01448 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APDCDNMF_01449 1.1e-181 phoH T phosphate starvation-inducible protein PhoH
APDCDNMF_01450 1.1e-167 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APDCDNMF_01451 1.6e-73 bioY S BioY family
APDCDNMF_01452 1.7e-262 argH 4.3.2.1 E argininosuccinate lyase
APDCDNMF_01453 1.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
APDCDNMF_01454 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
APDCDNMF_01455 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APDCDNMF_01456 5.5e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APDCDNMF_01457 8.3e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APDCDNMF_01458 3.4e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APDCDNMF_01459 3e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APDCDNMF_01460 1.1e-62 rplQ J Ribosomal protein L17
APDCDNMF_01461 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APDCDNMF_01462 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APDCDNMF_01463 3.6e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APDCDNMF_01464 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
APDCDNMF_01465 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APDCDNMF_01466 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APDCDNMF_01467 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APDCDNMF_01468 8.9e-64 rplO J Binds to the 23S rRNA
APDCDNMF_01469 2.9e-24 rpmD J Ribosomal protein L30
APDCDNMF_01470 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APDCDNMF_01471 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APDCDNMF_01472 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APDCDNMF_01473 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APDCDNMF_01474 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APDCDNMF_01475 1.7e-48 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APDCDNMF_01476 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APDCDNMF_01477 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APDCDNMF_01478 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
APDCDNMF_01479 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APDCDNMF_01480 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APDCDNMF_01481 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APDCDNMF_01482 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APDCDNMF_01483 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APDCDNMF_01484 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APDCDNMF_01485 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
APDCDNMF_01486 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APDCDNMF_01487 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
APDCDNMF_01488 7.6e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APDCDNMF_01489 3.1e-163
APDCDNMF_01490 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APDCDNMF_01491 2.6e-241 purD 6.3.4.13 F Belongs to the GARS family
APDCDNMF_01492 1.6e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
APDCDNMF_01493 1.2e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APDCDNMF_01494 1.1e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
APDCDNMF_01495 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APDCDNMF_01496 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APDCDNMF_01497 4.4e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APDCDNMF_01498 2.6e-36 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APDCDNMF_01499 5.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
APDCDNMF_01500 3.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APDCDNMF_01501 3.7e-218 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APDCDNMF_01502 7.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APDCDNMF_01503 3.6e-126 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
APDCDNMF_01504 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
APDCDNMF_01505 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
APDCDNMF_01506 1.1e-176 K AI-2E family transporter
APDCDNMF_01507 1.4e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
APDCDNMF_01508 3.7e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
APDCDNMF_01509 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APDCDNMF_01510 2.7e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APDCDNMF_01511 1.9e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APDCDNMF_01512 6.9e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APDCDNMF_01513 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
APDCDNMF_01514 7.4e-134 K LysR substrate binding domain
APDCDNMF_01515 5.6e-53 azlD S branched-chain amino acid
APDCDNMF_01516 3.2e-140 azlC E AzlC protein
APDCDNMF_01517 1.4e-201 hpk31 2.7.13.3 T Histidine kinase
APDCDNMF_01518 3.8e-125 K response regulator
APDCDNMF_01519 7.7e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APDCDNMF_01520 2.8e-171 deoR K sugar-binding domain protein
APDCDNMF_01521 3.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
APDCDNMF_01522 4.5e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
APDCDNMF_01523 3.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
APDCDNMF_01524 2.8e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APDCDNMF_01525 5.9e-135 XK27_01040 S Protein of unknown function (DUF1129)
APDCDNMF_01526 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APDCDNMF_01527 9.1e-32 yyzM S Bacterial protein of unknown function (DUF951)
APDCDNMF_01528 6.5e-154 spo0J K Belongs to the ParB family
APDCDNMF_01529 3.9e-139 soj D Sporulation initiation inhibitor
APDCDNMF_01530 9.6e-151 noc K Belongs to the ParB family
APDCDNMF_01531 2.3e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
APDCDNMF_01532 8.5e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
APDCDNMF_01533 2.5e-169 rihC 3.2.2.1 F Nucleoside
APDCDNMF_01534 1.3e-218 nupG F Nucleoside transporter
APDCDNMF_01535 2.7e-220 cycA E Amino acid permease
APDCDNMF_01537 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APDCDNMF_01538 3e-265 glnP P ABC transporter
APDCDNMF_01539 8.5e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APDCDNMF_01540 0.0 infB UW LPXTG-motif cell wall anchor domain protein
APDCDNMF_01541 0.0 fhaB M Rib/alpha-like repeat
APDCDNMF_01542 1.7e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
APDCDNMF_01543 3.9e-197 XK27_09615 S reductase
APDCDNMF_01544 2.7e-106 nqr 1.5.1.36 S reductase
APDCDNMF_01545 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APDCDNMF_01546 1.3e-182 K Transcriptional regulator, LacI family
APDCDNMF_01547 5.2e-259 G Major Facilitator
APDCDNMF_01548 1.5e-266 G Major Facilitator
APDCDNMF_01549 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
APDCDNMF_01550 1.1e-285 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
APDCDNMF_01551 9.4e-262 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
APDCDNMF_01552 7.9e-264 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
APDCDNMF_01553 5.4e-71
APDCDNMF_01554 6e-109 K Transcriptional regulator, TetR family
APDCDNMF_01555 2.7e-247 steT_1 E amino acid
APDCDNMF_01556 9.5e-135 puuD S peptidase C26
APDCDNMF_01558 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APDCDNMF_01559 1.4e-88
APDCDNMF_01560 1.5e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APDCDNMF_01561 3.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APDCDNMF_01562 1.5e-51 L hmm pf00665
APDCDNMF_01563 2e-282 pipD E Dipeptidase
APDCDNMF_01564 5.6e-242 pbuX F xanthine permease
APDCDNMF_01565 2.4e-251 nhaC C Na H antiporter NhaC
APDCDNMF_01566 2.4e-284 S C4-dicarboxylate anaerobic carrier
APDCDNMF_01567 7.2e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
APDCDNMF_01568 1.3e-41
APDCDNMF_01569 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
APDCDNMF_01570 3.4e-35 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
APDCDNMF_01571 7.8e-109 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
APDCDNMF_01572 4.6e-156 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
APDCDNMF_01573 3.8e-35
APDCDNMF_01574 1.7e-162 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
APDCDNMF_01575 1e-12 ydiN 5.4.99.5 G Major Facilitator
APDCDNMF_01576 2.5e-53 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
APDCDNMF_01577 5.1e-127 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APDCDNMF_01578 7.4e-132 ydiN G Major Facilitator Superfamily
APDCDNMF_01580 3.4e-206 G Transporter, major facilitator family protein
APDCDNMF_01581 0.0 S Bacterial membrane protein YfhO
APDCDNMF_01582 7.8e-105 T Ion transport 2 domain protein
APDCDNMF_01583 8.4e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
APDCDNMF_01585 0.0 L PLD-like domain
APDCDNMF_01586 5.5e-21
APDCDNMF_01587 4.6e-94 mrr L restriction endonuclease
APDCDNMF_01588 4.1e-167 L restriction endonuclease
APDCDNMF_01589 6.6e-92 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain protein
APDCDNMF_01590 8.9e-178 L Belongs to the 'phage' integrase family
APDCDNMF_01591 5.7e-68 3.1.21.3 V type I restriction modification DNA specificity domain protein
APDCDNMF_01592 7.7e-193 hsdM 2.1.1.72 V type I restriction-modification system
APDCDNMF_01593 4.6e-82 pipD E Dipeptidase
APDCDNMF_01594 1.8e-150 pipD E Dipeptidase
APDCDNMF_01595 9.5e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
APDCDNMF_01596 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APDCDNMF_01598 2.2e-57
APDCDNMF_01599 1.2e-180 prmA J Ribosomal protein L11 methyltransferase
APDCDNMF_01600 1.4e-125 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APDCDNMF_01601 1e-51
APDCDNMF_01602 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APDCDNMF_01603 4.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APDCDNMF_01604 2.7e-165 yniA G Phosphotransferase enzyme family
APDCDNMF_01605 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
APDCDNMF_01606 1.7e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APDCDNMF_01607 8e-261 glnPH2 P ABC transporter permease
APDCDNMF_01608 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
APDCDNMF_01609 4.3e-69 yqeY S YqeY-like protein
APDCDNMF_01610 2.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
APDCDNMF_01611 5.2e-22
APDCDNMF_01612 1.4e-19 D nuclear chromosome segregation
APDCDNMF_01614 6.8e-36 lytE M Lysin motif
APDCDNMF_01616 1.1e-62
APDCDNMF_01618 1e-58 ruvB 3.6.4.12 L four-way junction helicase activity
APDCDNMF_01619 7.6e-24 S YoeB-like toxin of bacterial type II toxin-antitoxin system
APDCDNMF_01620 3.7e-25 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
APDCDNMF_01625 8.1e-16
APDCDNMF_01626 6.1e-54 srtA 3.4.22.70 M sortase family
APDCDNMF_01631 1e-91 L Integrase
APDCDNMF_01632 3.3e-56 L Lactococcus lactis RepB C-terminus
APDCDNMF_01633 2.4e-19 S Lysin motif
APDCDNMF_01634 1.4e-102 L Replication initiation factor
APDCDNMF_01635 9e-37 L Single-strand binding protein family
APDCDNMF_01636 4.4e-83 L Phage integrase, N-terminal SAM-like domain
APDCDNMF_01637 1.8e-10
APDCDNMF_01641 1.1e-48 vsr L DNA mismatch endonuclease Vsr
APDCDNMF_01642 3e-157 dcm 2.1.1.37 H cytosine-specific methyltransferase
APDCDNMF_01643 6.6e-102 S NgoFVII restriction endonuclease
APDCDNMF_01644 1.4e-14 S Helix-turn-helix domain
APDCDNMF_01645 1.8e-42 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
APDCDNMF_01646 1e-182 arsB 1.20.4.1 P Sodium Bile acid symporter family
APDCDNMF_01647 3.1e-68 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APDCDNMF_01648 1.3e-52 cadX K Bacterial regulatory protein, arsR family
APDCDNMF_01649 2.8e-95 cadD P Cadmium resistance transporter
APDCDNMF_01652 2.7e-78 L Belongs to the 'phage' integrase family
APDCDNMF_01653 1.3e-10 E Zn peptidase
APDCDNMF_01654 2.8e-17 XK27_10050 K Peptidase S24-like
APDCDNMF_01659 4.4e-29 L Psort location Cytoplasmic, score
APDCDNMF_01684 1.7e-190 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
APDCDNMF_01685 4.4e-86 ygfC K transcriptional regulator (TetR family)
APDCDNMF_01686 5.4e-171 hrtB V ABC transporter permease
APDCDNMF_01687 6.7e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
APDCDNMF_01688 0.0 yhcA V ABC transporter, ATP-binding protein
APDCDNMF_01689 1.3e-37
APDCDNMF_01690 4.1e-50 czrA K Transcriptional regulator, ArsR family
APDCDNMF_01691 1e-240 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APDCDNMF_01692 1.3e-171 scrR K Transcriptional regulator, LacI family
APDCDNMF_01693 1e-24
APDCDNMF_01694 1.6e-106
APDCDNMF_01695 8.3e-205 yttB EGP Major facilitator Superfamily
APDCDNMF_01696 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
APDCDNMF_01697 8.5e-87
APDCDNMF_01698 1.5e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
APDCDNMF_01699 1.6e-193 M transferase activity, transferring glycosyl groups
APDCDNMF_01700 9.3e-200 waaB GT4 M Glycosyl transferases group 1
APDCDNMF_01701 8.3e-260 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
APDCDNMF_01702 1.4e-105 M biosynthesis protein
APDCDNMF_01703 1.6e-216 cps3F
APDCDNMF_01704 3.9e-220 glf 5.4.99.9 M UDP-galactopyranose mutase
APDCDNMF_01705 5.1e-116 rfbP 2.7.8.6 M Bacterial sugar transferase
APDCDNMF_01706 8e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
APDCDNMF_01707 6.7e-147 cps1D M Domain of unknown function (DUF4422)
APDCDNMF_01708 7.4e-141 recX 2.4.1.337 GT4 S Regulatory protein RecX
APDCDNMF_01709 1.9e-30
APDCDNMF_01710 1.9e-33 S Protein of unknown function (DUF2922)
APDCDNMF_01711 1.5e-153 yihY S Belongs to the UPF0761 family
APDCDNMF_01712 2e-280 yjeM E Amino Acid
APDCDNMF_01713 2.4e-127 3.2.1.23, 3.2.1.89 G arabinogalactan endo-1,4-beta-galactosidase activity
APDCDNMF_01714 3.9e-63 gntR1 K Transcriptional regulator, GntR family
APDCDNMF_01715 3.7e-154 V ABC transporter, ATP-binding protein
APDCDNMF_01716 8.7e-114
APDCDNMF_01717 2.3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
APDCDNMF_01718 4.9e-100 S Pfam:DUF3816
APDCDNMF_01719 0.0 clpE O Belongs to the ClpA ClpB family
APDCDNMF_01720 2.2e-27
APDCDNMF_01721 4e-38 ptsH G phosphocarrier protein HPR
APDCDNMF_01722 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APDCDNMF_01723 1.8e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
APDCDNMF_01724 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
APDCDNMF_01725 1.1e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APDCDNMF_01726 2.1e-224 S Uncharacterised protein family (UPF0236)
APDCDNMF_01727 1.3e-98 S dextransucrase activity
APDCDNMF_01728 1.4e-164 yueF S AI-2E family transporter
APDCDNMF_01729 4e-44 S Psort location CytoplasmicMembrane, score
APDCDNMF_01730 7.2e-220 S Psort location CytoplasmicMembrane, score
APDCDNMF_01731 1.4e-222 brpA K Cell envelope-like function transcriptional attenuator common domain protein
APDCDNMF_01732 3.1e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
APDCDNMF_01734 3.8e-48 S Domain of unknown function (DUF4393)
APDCDNMF_01735 4.3e-92 L Belongs to the 'phage' integrase family
APDCDNMF_01736 1e-23 sspC 2.7.7.7 DM Glucan-binding protein C
APDCDNMF_01737 9.7e-13 D Psort location Cellwall, score
APDCDNMF_01738 4.2e-33 XK27_00515 D Glucan-binding protein C
APDCDNMF_01740 9.1e-52 L Protein of unknown function (DUF3991)
APDCDNMF_01741 3.8e-136 topA2 5.99.1.2 G Topoisomerase IA
APDCDNMF_01743 6.7e-148 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APDCDNMF_01748 3.5e-196 U TraM recognition site of TraD and TraG
APDCDNMF_01749 1e-64
APDCDNMF_01751 8.1e-24
APDCDNMF_01752 3e-180 U type IV secretory pathway VirB4
APDCDNMF_01754 8e-38 M CHAP domain
APDCDNMF_01758 2.5e-29
APDCDNMF_01761 4.4e-51 E Filamentation induced by cAMP protein fic
APDCDNMF_01762 6.6e-78 S Fic/DOC family
APDCDNMF_01763 4.2e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APDCDNMF_01764 8.2e-51 S Iron-sulfur cluster assembly protein
APDCDNMF_01765 1e-151
APDCDNMF_01766 9.2e-176
APDCDNMF_01767 1.9e-86 dut S Protein conserved in bacteria
APDCDNMF_01770 5.8e-112 K Transcriptional regulator
APDCDNMF_01771 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
APDCDNMF_01772 1.6e-54 ysxB J Cysteine protease Prp
APDCDNMF_01773 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
APDCDNMF_01774 3.8e-128 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APDCDNMF_01775 1.4e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
APDCDNMF_01776 8.9e-111 J 2'-5' RNA ligase superfamily
APDCDNMF_01777 2.2e-70 yqhY S Asp23 family, cell envelope-related function
APDCDNMF_01778 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APDCDNMF_01779 1.2e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APDCDNMF_01780 2.3e-227 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APDCDNMF_01781 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APDCDNMF_01782 2.2e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APDCDNMF_01783 4.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
APDCDNMF_01784 5.6e-77 argR K Regulates arginine biosynthesis genes
APDCDNMF_01785 8e-262 recN L May be involved in recombinational repair of damaged DNA
APDCDNMF_01786 1.4e-53
APDCDNMF_01787 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
APDCDNMF_01788 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APDCDNMF_01789 4.6e-211 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APDCDNMF_01790 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APDCDNMF_01791 3.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APDCDNMF_01792 6.5e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APDCDNMF_01793 3.8e-131 stp 3.1.3.16 T phosphatase
APDCDNMF_01794 0.0 KLT serine threonine protein kinase
APDCDNMF_01795 2.7e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APDCDNMF_01796 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
APDCDNMF_01797 5.3e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
APDCDNMF_01798 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
APDCDNMF_01799 4.7e-58 asp S Asp23 family, cell envelope-related function
APDCDNMF_01800 0.0 yloV S DAK2 domain fusion protein YloV
APDCDNMF_01801 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APDCDNMF_01802 2.2e-185 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APDCDNMF_01803 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APDCDNMF_01804 8e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APDCDNMF_01805 0.0 smc D Required for chromosome condensation and partitioning
APDCDNMF_01806 9.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APDCDNMF_01807 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APDCDNMF_01808 1.3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APDCDNMF_01809 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
APDCDNMF_01810 4.1e-40 ylqC S Belongs to the UPF0109 family
APDCDNMF_01811 3.8e-90 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APDCDNMF_01812 1.3e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
APDCDNMF_01813 6.8e-262 yfnA E amino acid
APDCDNMF_01814 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APDCDNMF_01815 0.0 lacZ 3.2.1.23 G -beta-galactosidase
APDCDNMF_01816 0.0 lacS G Transporter
APDCDNMF_01817 2.4e-184 lacR K Transcriptional regulator
APDCDNMF_01818 6.6e-84
APDCDNMF_01819 9.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
APDCDNMF_01820 4.2e-53 S Mazg nucleotide pyrophosphohydrolase
APDCDNMF_01821 3.4e-35
APDCDNMF_01822 2.8e-154 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APDCDNMF_01823 6e-08
APDCDNMF_01825 1.1e-42 S Uncharacterised protein family (UPF0236)
APDCDNMF_01826 3e-306 S AAA domain, putative AbiEii toxin, Type IV TA system
APDCDNMF_01827 5.9e-205 3.6.4.12 L DNA helicase
APDCDNMF_01829 1.7e-111 lssY 3.6.1.27 I Acid phosphatase homologues
APDCDNMF_01830 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
APDCDNMF_01831 1.7e-227 clcA_2 P Chloride transporter, ClC family
APDCDNMF_01832 8.5e-119 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APDCDNMF_01833 1.8e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APDCDNMF_01834 1.2e-27 L Belongs to the 'phage' integrase family
APDCDNMF_01835 2.7e-112 ywnB S NAD(P)H-binding
APDCDNMF_01836 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
APDCDNMF_01837 2.5e-256 nhaC C Na H antiporter NhaC
APDCDNMF_01838 5.4e-184 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APDCDNMF_01840 1e-101 ydeN S Serine hydrolase
APDCDNMF_01841 1.3e-61 psiE S Phosphate-starvation-inducible E
APDCDNMF_01842 1.6e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APDCDNMF_01844 7.6e-39 S sequence-specific DNA binding transcription factor activity
APDCDNMF_01845 1.5e-113 pnuC H nicotinamide mononucleotide transporter
APDCDNMF_01848 5.8e-23 N mRNA binding
APDCDNMF_01849 3.3e-57 S HicB_like antitoxin of bacterial toxin-antitoxin system
APDCDNMF_01850 1.4e-177 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
APDCDNMF_01851 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
APDCDNMF_01852 1.1e-181 L Helix-turn-helix domain
APDCDNMF_01853 5e-153 L PFAM Integrase catalytic region
APDCDNMF_01854 3.4e-266 pipD E Dipeptidase
APDCDNMF_01855 8e-204 coiA 3.6.4.12 S Competence protein
APDCDNMF_01856 1e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
APDCDNMF_01857 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APDCDNMF_01858 2.3e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
APDCDNMF_01860 2.1e-214 L Transposase
APDCDNMF_01861 2.6e-90 L Integrase
APDCDNMF_01862 2.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
APDCDNMF_01863 3.3e-15 K Transcriptional regulator, LacI family
APDCDNMF_01864 2.9e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
APDCDNMF_01865 6.3e-57 yitW S Pfam:DUF59
APDCDNMF_01866 3.1e-33 L PFAM Integrase catalytic region
APDCDNMF_01868 1.8e-17 QT PucR C-terminal helix-turn-helix domain
APDCDNMF_01870 2.6e-26 S Protein of unknown function (DUF4065)
APDCDNMF_01872 9.8e-21 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
APDCDNMF_01873 2.1e-66 K Psort location Cytoplasmic, score
APDCDNMF_01874 8.8e-35 K DNA binding
APDCDNMF_01875 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
APDCDNMF_01876 7.5e-125 mod 2.1.1.72, 3.1.21.5 L DNA methylase
APDCDNMF_01877 9.7e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
APDCDNMF_01878 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APDCDNMF_01879 4.4e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APDCDNMF_01880 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APDCDNMF_01881 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
APDCDNMF_01882 7.2e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APDCDNMF_01883 9.8e-67 yabR J RNA binding
APDCDNMF_01884 6.6e-57 divIC D Septum formation initiator
APDCDNMF_01885 2.1e-39 yabO J S4 domain protein
APDCDNMF_01886 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APDCDNMF_01887 5.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APDCDNMF_01888 6.9e-113 S (CBS) domain
APDCDNMF_01889 2e-146 tesE Q hydratase
APDCDNMF_01890 9.8e-241 codA 3.5.4.1 F cytosine deaminase
APDCDNMF_01891 4.4e-250 U Belongs to the purine-cytosine permease (2.A.39) family
APDCDNMF_01892 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
APDCDNMF_01893 8.7e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APDCDNMF_01894 1.9e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APDCDNMF_01896 8e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APDCDNMF_01897 1.3e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
APDCDNMF_01898 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APDCDNMF_01899 2.2e-251 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APDCDNMF_01900 1.4e-164 glsA 3.5.1.2 E Belongs to the glutaminase family
APDCDNMF_01901 0.0 sprD D Domain of Unknown Function (DUF1542)
APDCDNMF_01902 5.3e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APDCDNMF_01903 2.6e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APDCDNMF_01904 1.5e-158 htpX O Belongs to the peptidase M48B family
APDCDNMF_01905 3.5e-92 lemA S LemA family
APDCDNMF_01906 2.3e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APDCDNMF_01907 1.2e-120 pgm3 G Belongs to the phosphoglycerate mutase family
APDCDNMF_01908 2.6e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
APDCDNMF_01909 4.4e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APDCDNMF_01910 2.5e-124 srtA 3.4.22.70 M sortase family
APDCDNMF_01911 6.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
APDCDNMF_01912 5.7e-239 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APDCDNMF_01913 4.6e-41 rpmE2 J Ribosomal protein L31
APDCDNMF_01914 4e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APDCDNMF_01915 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APDCDNMF_01916 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APDCDNMF_01917 3e-66 ywiB S Domain of unknown function (DUF1934)
APDCDNMF_01918 3.9e-145 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
APDCDNMF_01919 3.8e-270 ywfO S HD domain protein
APDCDNMF_01920 8.4e-148 yxeH S hydrolase
APDCDNMF_01921 2.6e-47
APDCDNMF_01922 3.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APDCDNMF_01923 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APDCDNMF_01924 6.5e-148 purR 2.4.2.7 F pur operon repressor
APDCDNMF_01925 4.7e-119 znuB U ABC 3 transport family
APDCDNMF_01926 3.8e-122 fhuC P ABC transporter
APDCDNMF_01927 3.3e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
APDCDNMF_01928 7.6e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APDCDNMF_01929 6.8e-37 veg S Biofilm formation stimulator VEG
APDCDNMF_01930 1.9e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APDCDNMF_01931 3.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APDCDNMF_01932 2.4e-155 tatD L hydrolase, TatD family
APDCDNMF_01933 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APDCDNMF_01934 8.1e-162 yunF F Protein of unknown function DUF72
APDCDNMF_01936 8.8e-130 cobB K SIR2 family
APDCDNMF_01937 1.1e-175
APDCDNMF_01938 1.5e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
APDCDNMF_01939 1.8e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
APDCDNMF_01940 2.9e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
APDCDNMF_01941 4.8e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
APDCDNMF_01942 8.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
APDCDNMF_01943 0.0 helD 3.6.4.12 L DNA helicase
APDCDNMF_01944 1.3e-202 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APDCDNMF_01945 1.9e-197 clcA P chloride
APDCDNMF_01946 8.1e-196 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APDCDNMF_01947 5.5e-38 Z012_10770 M Domain of unknown function (DUF1919)
APDCDNMF_01948 5.5e-48 cps2J S Polysaccharide biosynthesis protein
APDCDNMF_01949 2.5e-40 cps2J S Polysaccharide biosynthesis protein
APDCDNMF_01950 4.9e-38 M Glycosyltransferase like family 2
APDCDNMF_01952 4.4e-124 M Glycosyltransferase like family 2
APDCDNMF_01953 3e-27
APDCDNMF_01954 2.4e-127 M repeat protein
APDCDNMF_01955 1.2e-51 M KxYKxGKxW signal domain protein
APDCDNMF_01961 1.8e-08
APDCDNMF_01962 4e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
APDCDNMF_01963 5.6e-152 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APDCDNMF_01964 1.2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
APDCDNMF_01965 1.2e-114 yjbH Q Thioredoxin
APDCDNMF_01966 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
APDCDNMF_01967 6.2e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APDCDNMF_01968 1.7e-49 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APDCDNMF_01969 5.8e-115 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
APDCDNMF_01970 0.0 S SEC-C Motif Domain Protein
APDCDNMF_01971 1.4e-50
APDCDNMF_01972 1.6e-141 acmD M repeat protein
APDCDNMF_01973 7.1e-130 S enterobacterial common antigen metabolic process
APDCDNMF_01974 5.3e-283 O Arylsulfotransferase (ASST)
APDCDNMF_01994 5.9e-214 uhpT EGP Major facilitator Superfamily
APDCDNMF_01995 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
APDCDNMF_01996 1e-129 ponA V Beta-lactamase enzyme family
APDCDNMF_01997 3.8e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
APDCDNMF_01998 4.3e-74
APDCDNMF_01999 7e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
APDCDNMF_02000 8.1e-28
APDCDNMF_02001 7.6e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
APDCDNMF_02002 9.5e-294 L PFAM plasmid pRiA4b ORF-3 family protein
APDCDNMF_02003 1.9e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
APDCDNMF_02004 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APDCDNMF_02005 1.2e-160 mleR K LysR family
APDCDNMF_02006 2.9e-309 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
APDCDNMF_02007 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APDCDNMF_02008 3.6e-268 frdC 1.3.5.4 C FAD binding domain
APDCDNMF_02009 4.9e-252 yflS P Sodium:sulfate symporter transmembrane region
APDCDNMF_02010 6.3e-157 mleR K LysR family
APDCDNMF_02011 1.2e-250 yjjP S Putative threonine/serine exporter
APDCDNMF_02012 1.9e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
APDCDNMF_02013 1.4e-270 emrY EGP Major facilitator Superfamily
APDCDNMF_02014 3.3e-183 I Alpha beta
APDCDNMF_02015 1.2e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
APDCDNMF_02016 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APDCDNMF_02018 1.2e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
APDCDNMF_02019 1e-120 S Domain of unknown function (DUF4811)
APDCDNMF_02020 3.6e-269 lmrB EGP Major facilitator Superfamily
APDCDNMF_02021 5.2e-75 merR K MerR HTH family regulatory protein
APDCDNMF_02022 7.2e-56
APDCDNMF_02023 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APDCDNMF_02024 1.6e-216 S CAAX protease self-immunity
APDCDNMF_02025 6.1e-109 glnP P ABC transporter permease
APDCDNMF_02026 3.2e-110 gluC P ABC transporter permease
APDCDNMF_02027 2.2e-151 glnH ET ABC transporter
APDCDNMF_02028 5.3e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
APDCDNMF_02029 5.5e-83 usp1 T Belongs to the universal stress protein A family
APDCDNMF_02030 7.6e-110 S VIT family
APDCDNMF_02031 1.7e-117 S membrane
APDCDNMF_02032 3.5e-166 czcD P cation diffusion facilitator family transporter
APDCDNMF_02033 2e-123 sirR K iron dependent repressor
APDCDNMF_02034 7.9e-31 cspC K Cold shock protein
APDCDNMF_02035 2.1e-129 thrE S Putative threonine/serine exporter
APDCDNMF_02036 3e-81 S Threonine/Serine exporter, ThrE
APDCDNMF_02037 2.3e-119 lssY 3.6.1.27 I phosphatase
APDCDNMF_02038 5.4e-11 2.3.1.128 J Acetyltransferase (GNAT) domain
APDCDNMF_02039 1.1e-275 lysP E amino acid
APDCDNMF_02040 5.6e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
APDCDNMF_02046 4.7e-12
APDCDNMF_02047 1.7e-179 S Hydrolases of the alpha beta superfamily
APDCDNMF_02048 2.7e-196 adhP 1.1.1.1 C alcohol dehydrogenase
APDCDNMF_02049 1.7e-76 ctsR K Belongs to the CtsR family
APDCDNMF_02050 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
APDCDNMF_02051 1e-110 K Bacterial regulatory proteins, tetR family
APDCDNMF_02052 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APDCDNMF_02053 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APDCDNMF_02054 2.2e-202 ykiI
APDCDNMF_02055 5.7e-118 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
APDCDNMF_02056 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APDCDNMF_02057 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APDCDNMF_02058 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APDCDNMF_02059 1.3e-162 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
APDCDNMF_02060 1.9e-30 L Transposase
APDCDNMF_02061 1.9e-125 3.2.1.96, 3.5.1.28 GH73 M repeat protein
APDCDNMF_02062 8.7e-140 L hmm pf00665
APDCDNMF_02063 7.2e-96 L Helix-turn-helix domain
APDCDNMF_02064 2.4e-156 S Alpha beta hydrolase
APDCDNMF_02065 5.5e-158 gspA M family 8
APDCDNMF_02066 5e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
APDCDNMF_02067 9.4e-94
APDCDNMF_02068 6.4e-162 degV S EDD domain protein, DegV family
APDCDNMF_02069 0.0 FbpA K Fibronectin-binding protein
APDCDNMF_02070 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
APDCDNMF_02071 3.1e-206 carA 6.3.5.5 F Belongs to the CarA family
APDCDNMF_02072 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APDCDNMF_02073 7.7e-71 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APDCDNMF_02074 1.5e-65 esbA S Family of unknown function (DUF5322)
APDCDNMF_02075 4e-71 rnhA 3.1.26.4 L Ribonuclease HI
APDCDNMF_02076 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
APDCDNMF_02077 1.1e-83 F Belongs to the NrdI family
APDCDNMF_02078 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APDCDNMF_02079 1.7e-102 ypsA S Belongs to the UPF0398 family
APDCDNMF_02080 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APDCDNMF_02081 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
APDCDNMF_02082 1.3e-160 EG EamA-like transporter family
APDCDNMF_02083 2.8e-123 dnaD L DnaD domain protein
APDCDNMF_02084 4.9e-85 ypmB S Protein conserved in bacteria
APDCDNMF_02085 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
APDCDNMF_02086 5.3e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
APDCDNMF_02087 1.1e-165 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
APDCDNMF_02088 2.1e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
APDCDNMF_02089 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
APDCDNMF_02090 4.9e-87 S Protein of unknown function (DUF1440)
APDCDNMF_02091 0.0 rafA 3.2.1.22 G alpha-galactosidase
APDCDNMF_02092 3.7e-185 galR K Periplasmic binding protein-like domain
APDCDNMF_02093 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
APDCDNMF_02094 2.1e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APDCDNMF_02095 2.2e-123 lrgB M LrgB-like family
APDCDNMF_02096 1.9e-66 lrgA S LrgA family
APDCDNMF_02097 9.2e-130 lytT K response regulator receiver
APDCDNMF_02098 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
APDCDNMF_02099 1.5e-147 f42a O Band 7 protein
APDCDNMF_02100 3.8e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
APDCDNMF_02101 1.7e-153 yitU 3.1.3.104 S hydrolase
APDCDNMF_02102 2.7e-38 S Cytochrome B5
APDCDNMF_02103 6.3e-100 nreC K PFAM regulatory protein LuxR
APDCDNMF_02104 4.4e-158 hipB K Helix-turn-helix
APDCDNMF_02105 4.7e-57 yitW S Iron-sulfur cluster assembly protein
APDCDNMF_02106 2.3e-270 sufB O assembly protein SufB
APDCDNMF_02107 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
APDCDNMF_02108 3.1e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APDCDNMF_02109 9.6e-239 sufD O FeS assembly protein SufD
APDCDNMF_02110 3.2e-144 sufC O FeS assembly ATPase SufC
APDCDNMF_02111 4.2e-32 feoA P FeoA domain
APDCDNMF_02112 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
APDCDNMF_02113 3.1e-267 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
APDCDNMF_02114 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
APDCDNMF_02115 2.6e-64 ydiI Q Thioesterase superfamily
APDCDNMF_02116 7.1e-109 yvrI K RNA polymerase sigma factor, sigma-70 family
APDCDNMF_02117 2.8e-260 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
APDCDNMF_02127 3.4e-186 L Transposase
APDCDNMF_02128 4.3e-95
APDCDNMF_02129 7.7e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
APDCDNMF_02132 6.4e-42 L PFAM Integrase catalytic region
APDCDNMF_02134 2.5e-232 S Putative peptidoglycan binding domain
APDCDNMF_02135 5.3e-52 M NlpC P60 family protein
APDCDNMF_02136 1.2e-35
APDCDNMF_02138 3e-213 bacI V MacB-like periplasmic core domain
APDCDNMF_02139 9.8e-129 V ABC transporter
APDCDNMF_02140 4.4e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APDCDNMF_02141 5.2e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
APDCDNMF_02142 7.8e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APDCDNMF_02143 9.4e-149 E Glyoxalase-like domain
APDCDNMF_02144 7.5e-155 glcU U sugar transport
APDCDNMF_02145 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
APDCDNMF_02146 2.2e-96 S reductase
APDCDNMF_02147 1.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APDCDNMF_02148 2.7e-17 ABC-SBP S ABC transporter
APDCDNMF_02149 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
APDCDNMF_02150 1.9e-218 htrA 3.4.21.107 O serine protease
APDCDNMF_02151 2.3e-153 vicX 3.1.26.11 S domain protein
APDCDNMF_02152 5.4e-150 yycI S YycH protein
APDCDNMF_02153 1.5e-247 yycH S YycH protein
APDCDNMF_02154 0.0 vicK 2.7.13.3 T Histidine kinase
APDCDNMF_02155 5.2e-130 K response regulator
APDCDNMF_02157 3.4e-308 lmrA 3.6.3.44 V ABC transporter
APDCDNMF_02158 2.3e-72 K helix_turn_helix multiple antibiotic resistance protein
APDCDNMF_02160 5.7e-122 Z012_01130 S Fic/DOC family
APDCDNMF_02161 1.1e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
APDCDNMF_02162 4.8e-54
APDCDNMF_02163 2.2e-205 yttB EGP Major facilitator Superfamily
APDCDNMF_02164 6.9e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
APDCDNMF_02165 7.6e-74 rplI J Binds to the 23S rRNA
APDCDNMF_02166 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
APDCDNMF_02167 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APDCDNMF_02168 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APDCDNMF_02169 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
APDCDNMF_02170 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APDCDNMF_02171 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APDCDNMF_02172 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APDCDNMF_02173 6.4e-34 yaaA S S4 domain protein YaaA
APDCDNMF_02174 2.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APDCDNMF_02175 1.9e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APDCDNMF_02176 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
APDCDNMF_02177 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APDCDNMF_02178 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APDCDNMF_02179 9.7e-130 jag S R3H domain protein
APDCDNMF_02180 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APDCDNMF_02181 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APDCDNMF_02182 0.0 asnB 6.3.5.4 E Asparagine synthase
APDCDNMF_02183 2.4e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APDCDNMF_02184 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
APDCDNMF_02185 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
APDCDNMF_02186 1.6e-88 2.3.1.183 M Acetyltransferase GNAT family
APDCDNMF_02187 2.3e-159 S reductase
APDCDNMF_02189 1.9e-07 yiiE S Psort location CytoplasmicMembrane, score 10.00
APDCDNMF_02191 7.5e-57 K LysR substrate binding domain
APDCDNMF_02192 7.7e-299 S amidohydrolase
APDCDNMF_02194 4e-36 blpT
APDCDNMF_02195 6.5e-45 K LytTr DNA-binding domain
APDCDNMF_02196 1.9e-24 plnB 2.7.13.3 T GHKL domain
APDCDNMF_02198 1.6e-105 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)