ORF_ID e_value Gene_name EC_number CAZy COGs Description
COKDBBLI_00006 1.2e-19 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COKDBBLI_00007 4e-16 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
COKDBBLI_00008 4.6e-23 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COKDBBLI_00009 1.2e-10 T PFAM SpoVT AbrB
COKDBBLI_00011 4.9e-68
COKDBBLI_00013 3.4e-18 D nuclear chromosome segregation
COKDBBLI_00015 2.8e-260 xylT EGP Major facilitator Superfamily
COKDBBLI_00017 5.5e-217 xylR GK ROK family
COKDBBLI_00018 1.3e-28
COKDBBLI_00019 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
COKDBBLI_00020 2.4e-99 lacA 2.3.1.79 S Transferase hexapeptide repeat
COKDBBLI_00021 2e-155 glcU U sugar transport
COKDBBLI_00022 2.7e-269 yclK 2.7.13.3 T Histidine kinase
COKDBBLI_00023 8.8e-133 K response regulator
COKDBBLI_00025 6.3e-76 lytE M Lysin motif
COKDBBLI_00026 1e-69 L Transposase
COKDBBLI_00027 1.6e-149 L Transposase
COKDBBLI_00028 3.2e-220 L transposase IS116 IS110 IS902 family protein
COKDBBLI_00030 7.2e-52 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COKDBBLI_00031 7.3e-155 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
COKDBBLI_00032 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
COKDBBLI_00033 2.1e-166 cpsY K Transcriptional regulator, LysR family
COKDBBLI_00034 7.6e-61 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COKDBBLI_00035 3.9e-15 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COKDBBLI_00036 0.0 M LPXTG-motif cell wall anchor domain protein
COKDBBLI_00037 7.5e-102 cpsJ S glycosyl transferase family 2
COKDBBLI_00038 2.5e-302 M family 8
COKDBBLI_00039 1.6e-67 K Transcriptional regulator, HxlR family
COKDBBLI_00040 3.8e-128
COKDBBLI_00041 5.8e-103 K DNA-templated transcription, initiation
COKDBBLI_00042 3.4e-33
COKDBBLI_00043 3.1e-84
COKDBBLI_00044 6e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COKDBBLI_00045 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
COKDBBLI_00046 0.0 yjbQ P TrkA C-terminal domain protein
COKDBBLI_00047 3.8e-273 pipD E Dipeptidase
COKDBBLI_00049 3.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
COKDBBLI_00050 3.9e-209 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
COKDBBLI_00051 2.3e-75 M transferase activity, transferring glycosyl groups
COKDBBLI_00052 4.5e-89 cps3F
COKDBBLI_00053 3.9e-28 M biosynthesis protein
COKDBBLI_00054 6.9e-77 rgpB GT2 M Glycosyl transferase family 2
COKDBBLI_00055 4.4e-66 S Glycosyltransferase like family
COKDBBLI_00056 1.8e-79 glfT1 1.1.1.133 S Glycosyltransferase like family 2
COKDBBLI_00057 2e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
COKDBBLI_00058 3.9e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COKDBBLI_00059 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
COKDBBLI_00060 1.6e-114 yjbH Q Thioredoxin
COKDBBLI_00061 6.3e-265 pipD E Dipeptidase
COKDBBLI_00062 8e-204 coiA 3.6.4.12 S Competence protein
COKDBBLI_00063 5.2e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COKDBBLI_00064 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COKDBBLI_00065 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
COKDBBLI_00066 3e-226 lacZ 3.2.1.23 G -beta-galactosidase
COKDBBLI_00067 1.5e-120 lacZ 3.2.1.23 G -beta-galactosidase
COKDBBLI_00068 5.5e-220 lacS G Transporter
COKDBBLI_00069 1.6e-103 lacS G Transporter
COKDBBLI_00070 3e-99 lacR K Transcriptional regulator
COKDBBLI_00071 1.2e-59 lacR K Transcriptional regulator
COKDBBLI_00072 6.6e-84
COKDBBLI_00073 9.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
COKDBBLI_00074 8.4e-54 S Mazg nucleotide pyrophosphohydrolase
COKDBBLI_00075 3.8e-34
COKDBBLI_00076 5.2e-97 L Transposase
COKDBBLI_00077 3.9e-66 mrr L restriction endonuclease
COKDBBLI_00079 1.5e-18
COKDBBLI_00080 0.0 L PLD-like domain
COKDBBLI_00082 1.5e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
COKDBBLI_00083 1e-182 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COKDBBLI_00084 1e-94 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
COKDBBLI_00085 1.1e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
COKDBBLI_00086 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COKDBBLI_00087 9.5e-103 T Ion transport 2 domain protein
COKDBBLI_00088 0.0 S Bacterial membrane protein YfhO
COKDBBLI_00089 4.4e-206 G Transporter, major facilitator family protein
COKDBBLI_00090 4.6e-108 yvrI K RNA polymerase sigma factor, sigma-70 family
COKDBBLI_00091 1.2e-64 ydiI Q Thioesterase superfamily
COKDBBLI_00092 6.5e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
COKDBBLI_00093 1.3e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
COKDBBLI_00094 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
COKDBBLI_00095 4.2e-32 feoA P FeoA domain
COKDBBLI_00096 6.5e-145 sufC O FeS assembly ATPase SufC
COKDBBLI_00097 3.9e-240 sufD O FeS assembly protein SufD
COKDBBLI_00098 6.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COKDBBLI_00099 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
COKDBBLI_00100 6.7e-270 sufB O assembly protein SufB
COKDBBLI_00101 2.4e-56 yitW S Iron-sulfur cluster assembly protein
COKDBBLI_00102 1.4e-159 hipB K Helix-turn-helix
COKDBBLI_00103 1.6e-112 nreC K PFAM regulatory protein LuxR
COKDBBLI_00104 9.2e-39 S Cytochrome B5
COKDBBLI_00105 2.7e-154 yitU 3.1.3.104 S hydrolase
COKDBBLI_00106 5.5e-261 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
COKDBBLI_00107 1.8e-148 f42a O Band 7 protein
COKDBBLI_00108 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
COKDBBLI_00109 1.1e-130 lytT K response regulator receiver
COKDBBLI_00110 3.1e-41 lrgA S LrgA family
COKDBBLI_00111 1.3e-123 lrgB M LrgB-like family
COKDBBLI_00112 2.7e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COKDBBLI_00113 6.2e-173 scrK 2.7.1.2, 2.7.1.4 GK ROK family
COKDBBLI_00114 4.4e-186 galR K Periplasmic binding protein-like domain
COKDBBLI_00115 0.0 rafA 3.2.1.22 G alpha-galactosidase
COKDBBLI_00116 3.5e-85 S Protein of unknown function (DUF1440)
COKDBBLI_00117 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COKDBBLI_00118 4.6e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
COKDBBLI_00119 1.3e-171 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
COKDBBLI_00120 5.1e-173 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
COKDBBLI_00121 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
COKDBBLI_00122 4e-87 ypmB S Protein conserved in bacteria
COKDBBLI_00123 2.8e-123 dnaD L DnaD domain protein
COKDBBLI_00124 7.4e-161 EG EamA-like transporter family
COKDBBLI_00125 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
COKDBBLI_00126 3.7e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COKDBBLI_00127 2.9e-102 ypsA S Belongs to the UPF0398 family
COKDBBLI_00128 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COKDBBLI_00129 1.5e-83 F Belongs to the NrdI family
COKDBBLI_00130 3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
COKDBBLI_00131 1.7e-69 rnhA 3.1.26.4 L Ribonuclease HI
COKDBBLI_00132 7.3e-65 esbA S Family of unknown function (DUF5322)
COKDBBLI_00133 1.7e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COKDBBLI_00134 1.2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COKDBBLI_00135 1.1e-206 carA 6.3.5.5 F Belongs to the CarA family
COKDBBLI_00136 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COKDBBLI_00137 0.0 FbpA K Fibronectin-binding protein
COKDBBLI_00138 6.4e-162 degV S EDD domain protein, DegV family
COKDBBLI_00139 9.4e-94
COKDBBLI_00140 5e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
COKDBBLI_00141 2.3e-136 gspA M family 8
COKDBBLI_00142 1.3e-125 S Alpha beta hydrolase
COKDBBLI_00143 3.6e-24 S Alpha beta hydrolase
COKDBBLI_00144 1.8e-95 K Acetyltransferase (GNAT) domain
COKDBBLI_00145 3.4e-107 XK27_08635 S UPF0210 protein
COKDBBLI_00146 4.1e-50 XK27_08635 S UPF0210 protein
COKDBBLI_00147 1.8e-38 gcvR T Belongs to the UPF0237 family
COKDBBLI_00148 1.8e-167 1.1.1.346 C Aldo keto reductase
COKDBBLI_00149 1.6e-42 K Transcriptional regulator
COKDBBLI_00150 3.7e-151 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COKDBBLI_00151 6.4e-262 G Peptidase_C39 like family
COKDBBLI_00152 3.3e-163 yueF S AI-2E family transporter
COKDBBLI_00153 5.8e-224 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COKDBBLI_00154 1.8e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COKDBBLI_00155 2.1e-146 2.3.1.19 K Helix-turn-helix XRE-family like proteins
COKDBBLI_00156 4.1e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COKDBBLI_00157 8.8e-47 gcvH E glycine cleavage
COKDBBLI_00158 1.1e-220 rodA D Belongs to the SEDS family
COKDBBLI_00159 5.2e-31 S Protein of unknown function (DUF2969)
COKDBBLI_00160 5.5e-178 mbl D Cell shape determining protein MreB Mrl
COKDBBLI_00161 2.5e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COKDBBLI_00162 2.2e-33 ywzB S Protein of unknown function (DUF1146)
COKDBBLI_00163 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COKDBBLI_00164 5.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COKDBBLI_00165 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COKDBBLI_00166 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COKDBBLI_00167 3.3e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COKDBBLI_00168 3.3e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COKDBBLI_00169 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COKDBBLI_00170 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
COKDBBLI_00171 2.2e-232 pyrP F Permease
COKDBBLI_00172 2.2e-129 yibF S overlaps another CDS with the same product name
COKDBBLI_00173 2.9e-191 yibE S overlaps another CDS with the same product name
COKDBBLI_00174 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COKDBBLI_00175 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COKDBBLI_00176 1.2e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COKDBBLI_00177 4.7e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COKDBBLI_00178 1.4e-164 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COKDBBLI_00179 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COKDBBLI_00180 6e-108 tdk 2.7.1.21 F thymidine kinase
COKDBBLI_00181 9.8e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
COKDBBLI_00182 1.6e-134 cobQ S CobB/CobQ-like glutamine amidotransferase domain
COKDBBLI_00183 3.6e-223 arcD U Amino acid permease
COKDBBLI_00184 7.5e-261 E Arginine ornithine antiporter
COKDBBLI_00185 2.7e-79 argR K Regulates arginine biosynthesis genes
COKDBBLI_00186 1.3e-237 arcA 3.5.3.6 E Arginine
COKDBBLI_00187 1.6e-188 ampC V Beta-lactamase
COKDBBLI_00188 4.6e-34
COKDBBLI_00189 0.0 M domain protein
COKDBBLI_00190 2e-91
COKDBBLI_00192 2e-251 yjcE P Sodium proton antiporter
COKDBBLI_00193 3.6e-57
COKDBBLI_00195 1.3e-87
COKDBBLI_00196 0.0 copA 3.6.3.54 P P-type ATPase
COKDBBLI_00197 1.8e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COKDBBLI_00198 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COKDBBLI_00199 1.7e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
COKDBBLI_00200 1.4e-156 EG EamA-like transporter family
COKDBBLI_00201 4.4e-169 arcC 2.7.2.2 E Belongs to the carbamate kinase family
COKDBBLI_00202 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COKDBBLI_00203 6.2e-154 KT YcbB domain
COKDBBLI_00204 3.5e-301 xylB 2.7.1.17 G Belongs to the FGGY kinase family
COKDBBLI_00205 1.3e-270 xylA 5.3.1.5 G Belongs to the xylose isomerase family
COKDBBLI_00206 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
COKDBBLI_00207 1.8e-36 L Reverse transcriptase (RNA-dependent DNA polymerase)
COKDBBLI_00208 2e-46 doc S Fic/DOC family
COKDBBLI_00210 7.1e-127 L Belongs to the 'phage' integrase family
COKDBBLI_00211 6.3e-20
COKDBBLI_00214 0.0
COKDBBLI_00215 3.7e-144
COKDBBLI_00216 8.4e-51 marR K Transcriptional regulator, MarR family
COKDBBLI_00217 4.2e-99 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COKDBBLI_00218 2.1e-52 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COKDBBLI_00219 2.5e-31 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COKDBBLI_00220 5.2e-149 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
COKDBBLI_00221 9.6e-119 IQ reductase
COKDBBLI_00222 1.1e-57 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
COKDBBLI_00223 1.2e-48 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
COKDBBLI_00224 6.8e-107 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
COKDBBLI_00225 1.1e-53 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COKDBBLI_00226 1.3e-134 accA 2.1.3.15, 6.4.1.2 I alpha subunit
COKDBBLI_00227 4.3e-74
COKDBBLI_00228 5.3e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COKDBBLI_00229 3.8e-129 ponA V Beta-lactamase enzyme family
COKDBBLI_00230 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
COKDBBLI_00231 3.5e-214 uhpT EGP Major facilitator Superfamily
COKDBBLI_00232 1.1e-57 S AAA ATPase domain
COKDBBLI_00234 9.3e-20
COKDBBLI_00235 4.6e-20 E Zn peptidase
COKDBBLI_00236 2.4e-26 ps115 K Helix-turn-helix XRE-family like proteins
COKDBBLI_00237 3.6e-18
COKDBBLI_00241 9.7e-20
COKDBBLI_00244 7.1e-166 yniA G Phosphotransferase enzyme family
COKDBBLI_00245 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COKDBBLI_00246 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COKDBBLI_00247 5.2e-260 glnPH2 P ABC transporter permease
COKDBBLI_00249 4.5e-59 S HicB_like antitoxin of bacterial toxin-antitoxin system
COKDBBLI_00250 6e-22
COKDBBLI_00251 1.3e-259 S Phage terminase, large subunit
COKDBBLI_00252 0.0 S Phage portal protein, SPP1 Gp6-like
COKDBBLI_00253 2.2e-171 S Phage Mu protein F like protein
COKDBBLI_00255 3.1e-75 ykiI
COKDBBLI_00256 3.4e-118 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
COKDBBLI_00257 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COKDBBLI_00258 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COKDBBLI_00259 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COKDBBLI_00260 4.8e-61 L Transposase
COKDBBLI_00261 1.5e-172 rhaS2 K Transcriptional regulator, AraC family
COKDBBLI_00262 6.2e-290 xynT G MFS/sugar transport protein
COKDBBLI_00263 0.0 3.2.1.55 GH51 G Right handed beta helix region
COKDBBLI_00264 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
COKDBBLI_00265 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COKDBBLI_00266 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COKDBBLI_00267 5.4e-228 aadAT EK Aminotransferase, class I
COKDBBLI_00269 6.5e-179 M Glycosyl transferase family group 2
COKDBBLI_00270 2.4e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COKDBBLI_00271 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COKDBBLI_00272 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COKDBBLI_00273 5.9e-48
COKDBBLI_00275 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COKDBBLI_00276 1.1e-56 K transcriptional regulator PadR family
COKDBBLI_00277 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
COKDBBLI_00278 5.2e-136 S Putative adhesin
COKDBBLI_00279 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
COKDBBLI_00280 1.3e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COKDBBLI_00281 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COKDBBLI_00282 3.4e-35 nrdH O Glutaredoxin
COKDBBLI_00283 6.5e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COKDBBLI_00284 3.1e-291 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COKDBBLI_00285 4.6e-46 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COKDBBLI_00286 4.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COKDBBLI_00287 9.7e-39 S Protein of unknown function (DUF2508)
COKDBBLI_00288 4.3e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COKDBBLI_00289 7.6e-52 yaaQ S Cyclic-di-AMP receptor
COKDBBLI_00290 1.8e-184 holB 2.7.7.7 L DNA polymerase III
COKDBBLI_00291 5.9e-58 yabA L Involved in initiation control of chromosome replication
COKDBBLI_00292 3.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COKDBBLI_00293 3.6e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
COKDBBLI_00294 3.4e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COKDBBLI_00295 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COKDBBLI_00296 1.3e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COKDBBLI_00297 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COKDBBLI_00298 3e-125 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
COKDBBLI_00299 4.7e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
COKDBBLI_00300 8e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COKDBBLI_00301 3.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COKDBBLI_00302 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COKDBBLI_00303 9.9e-138 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COKDBBLI_00304 1.7e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
COKDBBLI_00305 6.9e-228 mtnE 2.6.1.83 E Aminotransferase
COKDBBLI_00306 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COKDBBLI_00307 0.0 uup S ABC transporter, ATP-binding protein
COKDBBLI_00308 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COKDBBLI_00309 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COKDBBLI_00310 3.2e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COKDBBLI_00311 3.4e-80 S YbaK proline--tRNA ligase associated domain protein
COKDBBLI_00312 2e-302 ybeC E amino acid
COKDBBLI_00313 0.0 ydaO E amino acid
COKDBBLI_00314 3e-38
COKDBBLI_00315 1e-64 rmaI K Transcriptional regulator
COKDBBLI_00316 5.6e-24 yaaU EGP Major facilitator Superfamily
COKDBBLI_00317 1.6e-86 yaaU EGP Major facilitator Superfamily
COKDBBLI_00318 5.1e-76 EGP Major facilitator Superfamily
COKDBBLI_00319 8.3e-111 yvyE 3.4.13.9 S YigZ family
COKDBBLI_00320 6.6e-259 comFA L Helicase C-terminal domain protein
COKDBBLI_00321 2e-126 comFC S Competence protein
COKDBBLI_00322 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COKDBBLI_00323 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COKDBBLI_00324 3.9e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COKDBBLI_00325 5.3e-32 KT PspC domain protein
COKDBBLI_00326 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
COKDBBLI_00327 6.6e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COKDBBLI_00328 1.2e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COKDBBLI_00329 2.2e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
COKDBBLI_00330 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COKDBBLI_00331 8.7e-136 yrjD S LUD domain
COKDBBLI_00332 1.3e-287 lutB C 4Fe-4S dicluster domain
COKDBBLI_00333 1.7e-156 lutA C Cysteine-rich domain
COKDBBLI_00334 3.9e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COKDBBLI_00335 3.2e-209 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COKDBBLI_00336 4.1e-164 aatB ET PFAM extracellular solute-binding protein, family 3
COKDBBLI_00337 3.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
COKDBBLI_00338 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COKDBBLI_00347 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COKDBBLI_00348 4.3e-64 rfbJ M Glycosyl transferase family 2
COKDBBLI_00349 7.1e-153 spoU 2.1.1.185 J Methyltransferase
COKDBBLI_00350 2.7e-55 pnuC H nicotinamide mononucleotide transporter
COKDBBLI_00351 3.1e-50 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
COKDBBLI_00352 4.5e-163 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
COKDBBLI_00353 7.1e-101 ywlG S Belongs to the UPF0340 family
COKDBBLI_00354 2.7e-76
COKDBBLI_00355 9.8e-180
COKDBBLI_00356 1.4e-181 fecB P Periplasmic binding protein
COKDBBLI_00357 1.4e-139 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
COKDBBLI_00358 3.4e-81 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COKDBBLI_00359 6.3e-57 yitW S Pfam:DUF59
COKDBBLI_00360 8.6e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
COKDBBLI_00361 1.6e-14 K Transcriptional regulator, LacI family
COKDBBLI_00362 1.3e-84 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
COKDBBLI_00363 1.5e-90 L Integrase
COKDBBLI_00364 2.9e-14 K Transcriptional
COKDBBLI_00365 3.6e-149 endA V DNA/RNA non-specific endonuclease
COKDBBLI_00366 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COKDBBLI_00367 2.3e-41 ybaN S Protein of unknown function (DUF454)
COKDBBLI_00368 1.4e-146 rgpAc GT4 M Domain of unknown function (DUF1972)
COKDBBLI_00369 1.3e-126 G Glycosyltransferase Family 4
COKDBBLI_00370 5.3e-60 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
COKDBBLI_00371 2.8e-30 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
COKDBBLI_00372 1.9e-165 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COKDBBLI_00373 3.9e-135 epsB M biosynthesis protein
COKDBBLI_00374 9e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
COKDBBLI_00375 7.5e-107 rfbP M Bacterial sugar transferase
COKDBBLI_00376 7.8e-15 dam2 2.1.1.72 L DNA methyltransferase
COKDBBLI_00377 9.5e-139 L Belongs to the 'phage' integrase family
COKDBBLI_00379 4e-49 yrvD S Pfam:DUF1049
COKDBBLI_00380 9.9e-149 3.1.3.102, 3.1.3.104 S hydrolase
COKDBBLI_00381 1e-229 V N-6 DNA Methylase
COKDBBLI_00383 3e-145 clpB O Belongs to the ClpA ClpB family
COKDBBLI_00386 6.6e-11 3.1.21.3 V type I restriction modification DNA specificity domain
COKDBBLI_00387 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
COKDBBLI_00388 3.8e-70 yqeY S YqeY-like protein
COKDBBLI_00389 4.2e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COKDBBLI_00390 3.5e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
COKDBBLI_00391 1.2e-260 argH 4.3.2.1 E argininosuccinate lyase
COKDBBLI_00392 4.8e-73 bioY S BioY family
COKDBBLI_00393 8.7e-168 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COKDBBLI_00394 1.3e-182 phoH T phosphate starvation-inducible protein PhoH
COKDBBLI_00395 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COKDBBLI_00396 1.9e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
COKDBBLI_00397 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COKDBBLI_00398 8.4e-145 recO L Involved in DNA repair and RecF pathway recombination
COKDBBLI_00399 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
COKDBBLI_00400 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
COKDBBLI_00401 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COKDBBLI_00402 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COKDBBLI_00403 9.1e-220 patA 2.6.1.1 E Aminotransferase
COKDBBLI_00404 9.2e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
COKDBBLI_00405 4.5e-157 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COKDBBLI_00406 4.6e-238 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COKDBBLI_00407 3e-30 S Protein of unknown function (DUF2929)
COKDBBLI_00408 0.0 dnaE 2.7.7.7 L DNA polymerase
COKDBBLI_00409 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
COKDBBLI_00410 1.6e-168 cvfB S S1 domain
COKDBBLI_00411 2.2e-165 xerD D recombinase XerD
COKDBBLI_00412 1.6e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COKDBBLI_00413 6.9e-139 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COKDBBLI_00414 8.5e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COKDBBLI_00415 9e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COKDBBLI_00416 7.6e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COKDBBLI_00417 4.7e-188 ypbB 5.1.3.1 S Helix-turn-helix domain
COKDBBLI_00418 2.8e-263 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
COKDBBLI_00419 2.5e-13 M Lysin motif
COKDBBLI_00420 7.9e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
COKDBBLI_00421 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
COKDBBLI_00422 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
COKDBBLI_00423 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COKDBBLI_00424 2.4e-234 S Tetratricopeptide repeat protein
COKDBBLI_00425 2.4e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COKDBBLI_00426 0.0 yfmR S ABC transporter, ATP-binding protein
COKDBBLI_00427 2.7e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COKDBBLI_00428 1.2e-88 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COKDBBLI_00429 1.7e-111 hlyIII S protein, hemolysin III
COKDBBLI_00430 2.2e-151 DegV S EDD domain protein, DegV family
COKDBBLI_00431 3.4e-169 ypmR E lipolytic protein G-D-S-L family
COKDBBLI_00432 3.1e-107 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
COKDBBLI_00433 5.8e-35 yozE S Belongs to the UPF0346 family
COKDBBLI_00434 1.1e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COKDBBLI_00435 7.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COKDBBLI_00436 1.3e-159 dprA LU DNA protecting protein DprA
COKDBBLI_00437 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COKDBBLI_00438 2.3e-167 lacX 5.1.3.3 G Aldose 1-epimerase
COKDBBLI_00439 9.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COKDBBLI_00440 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COKDBBLI_00441 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COKDBBLI_00442 1.8e-83 F Hydrolase, NUDIX family
COKDBBLI_00443 2.3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
COKDBBLI_00444 1.1e-68 yqkB S Belongs to the HesB IscA family
COKDBBLI_00445 4.2e-50
COKDBBLI_00447 6.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
COKDBBLI_00448 8.2e-61 asp S Asp23 family, cell envelope-related function
COKDBBLI_00449 2.1e-25
COKDBBLI_00450 8.5e-96
COKDBBLI_00451 7e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
COKDBBLI_00452 1.2e-180 K Transcriptional regulator, LacI family
COKDBBLI_00453 9e-221 gntT EG Gluconate
COKDBBLI_00454 8.9e-292 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
COKDBBLI_00455 3.2e-95 K Acetyltransferase (GNAT) domain
COKDBBLI_00456 2.1e-90 ntd 2.4.2.6 F Nucleoside
COKDBBLI_00457 3.4e-21
COKDBBLI_00458 3.6e-165 S Alpha/beta hydrolase of unknown function (DUF915)
COKDBBLI_00459 4.7e-114 yviA S Protein of unknown function (DUF421)
COKDBBLI_00460 4.5e-71 S Protein of unknown function (DUF3290)
COKDBBLI_00461 1.6e-78 L Belongs to the 'phage' integrase family
COKDBBLI_00462 1.6e-10 E Zn peptidase
COKDBBLI_00463 2.9e-11 S protein disulfide oxidoreductase activity
COKDBBLI_00465 7e-245 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COKDBBLI_00466 8.3e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
COKDBBLI_00471 2.3e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
COKDBBLI_00472 2.9e-99 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COKDBBLI_00473 1.7e-84 L PFAM transposase IS200-family protein
COKDBBLI_00474 6.2e-199 xerS L Belongs to the 'phage' integrase family
COKDBBLI_00476 2.8e-215 ugd 1.1.1.22 M UDP binding domain
COKDBBLI_00477 3.2e-47 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COKDBBLI_00478 6.6e-290 mntH P H( )-stimulated, divalent metal cation uptake system
COKDBBLI_00479 3.4e-132 O Bacterial dnaA protein
COKDBBLI_00480 4.5e-238 L Integrase core domain
COKDBBLI_00481 1.5e-41 lpg2 2.4.1.337 GT4 M transferase activity, transferring glycosyl groups
COKDBBLI_00482 1.1e-72 M transferase activity, transferring glycosyl groups
COKDBBLI_00483 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COKDBBLI_00484 1.6e-167
COKDBBLI_00485 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COKDBBLI_00486 8.2e-243 purD 6.3.4.13 F Belongs to the GARS family
COKDBBLI_00487 2.8e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
COKDBBLI_00488 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COKDBBLI_00489 6.2e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
COKDBBLI_00490 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COKDBBLI_00491 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COKDBBLI_00492 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COKDBBLI_00493 3.8e-35 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COKDBBLI_00494 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
COKDBBLI_00495 4.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COKDBBLI_00496 1.9e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COKDBBLI_00497 5.6e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COKDBBLI_00498 2.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COKDBBLI_00499 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
COKDBBLI_00500 2.2e-186 thrC 4.2.3.1 E Threonine synthase
COKDBBLI_00501 6.7e-125 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
COKDBBLI_00502 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
COKDBBLI_00503 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
COKDBBLI_00504 1.1e-176 K AI-2E family transporter
COKDBBLI_00505 4.1e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
COKDBBLI_00506 1.6e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
COKDBBLI_00507 7.4e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COKDBBLI_00508 7.8e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COKDBBLI_00509 5.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COKDBBLI_00510 9.9e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COKDBBLI_00511 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COKDBBLI_00512 1e-82 K LysR substrate binding domain
COKDBBLI_00513 1.9e-26 K LysR substrate binding domain
COKDBBLI_00514 5.6e-53 azlD S branched-chain amino acid
COKDBBLI_00515 2.9e-141 azlC E AzlC protein
COKDBBLI_00516 5.9e-200 hpk31 2.7.13.3 T Histidine kinase
COKDBBLI_00517 3.8e-125 K response regulator
COKDBBLI_00518 1.7e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COKDBBLI_00519 4.7e-171 deoR K sugar-binding domain protein
COKDBBLI_00520 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
COKDBBLI_00521 1.2e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
COKDBBLI_00522 1.8e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
COKDBBLI_00523 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
COKDBBLI_00524 9.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
COKDBBLI_00525 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COKDBBLI_00526 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
COKDBBLI_00527 6.5e-154 spo0J K Belongs to the ParB family
COKDBBLI_00528 3.9e-139 soj D Sporulation initiation inhibitor
COKDBBLI_00529 9.6e-151 noc K Belongs to the ParB family
COKDBBLI_00530 4.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
COKDBBLI_00531 2.1e-160 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
COKDBBLI_00532 8.7e-170 rihC 3.2.2.1 F Nucleoside
COKDBBLI_00533 2.3e-218 nupG F Nucleoside transporter
COKDBBLI_00534 9.4e-221 cycA E Amino acid permease
COKDBBLI_00535 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COKDBBLI_00536 1.5e-264 glnP P ABC transporter
COKDBBLI_00537 7.6e-52 ruvB 3.6.4.12 L four-way junction helicase activity
COKDBBLI_00539 3.5e-93 comA V Peptidase C39 family
COKDBBLI_00540 3.8e-94
COKDBBLI_00541 3.5e-24
COKDBBLI_00544 7.2e-96 L Helix-turn-helix domain
COKDBBLI_00545 5.6e-261 S Uncharacterised protein family (UPF0236)
COKDBBLI_00546 9.2e-264 L PFAM Integrase catalytic region
COKDBBLI_00549 1.3e-162 I alpha/beta hydrolase fold
COKDBBLI_00550 1.8e-196 EGP Major facilitator Superfamily
COKDBBLI_00551 9.2e-110 M Lysin motif
COKDBBLI_00552 6.2e-79
COKDBBLI_00553 2.8e-168 P CorA-like Mg2+ transporter protein
COKDBBLI_00554 1.6e-96 wecD3 K PFAM GCN5-related N-acetyltransferase
COKDBBLI_00555 7e-159 cytX U Belongs to the purine-cytosine permease (2.A.39) family
COKDBBLI_00556 4.3e-13
COKDBBLI_00557 1.5e-77 S Domain of unknown function (DUF4767)
COKDBBLI_00558 6.9e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
COKDBBLI_00559 4.3e-112 S Membrane
COKDBBLI_00560 9.9e-126 O Zinc-dependent metalloprotease
COKDBBLI_00561 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COKDBBLI_00562 2.9e-159 metQ_4 P Belongs to the nlpA lipoprotein family
COKDBBLI_00564 0.0 UW LPXTG-motif cell wall anchor domain protein
COKDBBLI_00565 1.3e-90 UW LPXTG-motif cell wall anchor domain protein
COKDBBLI_00566 0.0 UW LPXTG-motif cell wall anchor domain protein
COKDBBLI_00567 0.0 UW LPXTG-motif cell wall anchor domain protein
COKDBBLI_00568 4.9e-183 S Phosphotransferase system, EIIC
COKDBBLI_00569 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COKDBBLI_00570 1.2e-164
COKDBBLI_00572 4.4e-25 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COKDBBLI_00573 1.9e-22 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COKDBBLI_00574 2.8e-96 2.3.1.128 K acetyltransferase
COKDBBLI_00575 6.4e-22
COKDBBLI_00576 1.7e-32
COKDBBLI_00577 2.1e-31
COKDBBLI_00585 2.2e-44
COKDBBLI_00586 3.1e-25 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
COKDBBLI_00587 4.9e-12 S Acyltransferase family
COKDBBLI_00594 4.4e-51 E Filamentation induced by cAMP protein fic
COKDBBLI_00595 1.9e-77 S Fic/DOC family
COKDBBLI_00596 3.6e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COKDBBLI_00597 8.2e-51 S Iron-sulfur cluster assembly protein
COKDBBLI_00598 5.2e-151
COKDBBLI_00599 1.2e-172
COKDBBLI_00600 8.7e-87 dut S Protein conserved in bacteria
COKDBBLI_00603 5.8e-112 K Transcriptional regulator
COKDBBLI_00604 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
COKDBBLI_00605 3.7e-54 ysxB J Cysteine protease Prp
COKDBBLI_00606 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
COKDBBLI_00607 7.1e-127 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COKDBBLI_00608 5.2e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COKDBBLI_00609 9.8e-110 J 2'-5' RNA ligase superfamily
COKDBBLI_00610 8.4e-70 yqhY S Asp23 family, cell envelope-related function
COKDBBLI_00611 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COKDBBLI_00612 2.1e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COKDBBLI_00613 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COKDBBLI_00614 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COKDBBLI_00615 8.4e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COKDBBLI_00616 5.3e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
COKDBBLI_00617 2.5e-77 argR K Regulates arginine biosynthesis genes
COKDBBLI_00618 1.8e-261 recN L May be involved in recombinational repair of damaged DNA
COKDBBLI_00619 1.4e-53
COKDBBLI_00620 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
COKDBBLI_00621 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COKDBBLI_00622 1.2e-211 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COKDBBLI_00623 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COKDBBLI_00624 3.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COKDBBLI_00625 8.4e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COKDBBLI_00626 8.5e-131 stp 3.1.3.16 T phosphatase
COKDBBLI_00627 0.0 KLT serine threonine protein kinase
COKDBBLI_00628 2.7e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COKDBBLI_00629 3.6e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
COKDBBLI_00630 4.8e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
COKDBBLI_00631 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
COKDBBLI_00632 4.7e-58 asp S Asp23 family, cell envelope-related function
COKDBBLI_00633 0.0 yloV S DAK2 domain fusion protein YloV
COKDBBLI_00634 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COKDBBLI_00635 4.6e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COKDBBLI_00636 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COKDBBLI_00637 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COKDBBLI_00638 0.0 smc D Required for chromosome condensation and partitioning
COKDBBLI_00639 1.4e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COKDBBLI_00640 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COKDBBLI_00641 3.9e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COKDBBLI_00642 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COKDBBLI_00643 2.7e-39 ylqC S Belongs to the UPF0109 family
COKDBBLI_00644 5e-90 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COKDBBLI_00645 1.3e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COKDBBLI_00646 4.4e-261 yfnA E amino acid
COKDBBLI_00647 2.5e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COKDBBLI_00650 1.5e-12
COKDBBLI_00651 1.4e-67 rfbJ M Glycosyl transferase family 2
COKDBBLI_00655 7.7e-58
COKDBBLI_00656 7.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COKDBBLI_00657 8.8e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COKDBBLI_00658 4.2e-217 patA 2.6.1.1 E Aminotransferase
COKDBBLI_00659 1.5e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COKDBBLI_00660 5.9e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COKDBBLI_00661 1.9e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COKDBBLI_00662 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COKDBBLI_00663 1.1e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COKDBBLI_00664 3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
COKDBBLI_00665 1.1e-184 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COKDBBLI_00666 8.1e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COKDBBLI_00667 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COKDBBLI_00668 9e-119 S Repeat protein
COKDBBLI_00669 3.7e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
COKDBBLI_00670 5.3e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COKDBBLI_00671 2.8e-57 XK27_04120 S Putative amino acid metabolism
COKDBBLI_00672 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
COKDBBLI_00673 2.2e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COKDBBLI_00675 2.4e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
COKDBBLI_00676 4.2e-32 cspA K Cold shock protein
COKDBBLI_00677 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COKDBBLI_00678 1.9e-42 divIVA D DivIVA domain protein
COKDBBLI_00679 7.8e-143 ylmH S S4 domain protein
COKDBBLI_00680 1.4e-40 yggT S YGGT family
COKDBBLI_00681 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COKDBBLI_00682 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COKDBBLI_00683 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COKDBBLI_00684 6.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COKDBBLI_00685 7.3e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COKDBBLI_00686 1.7e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COKDBBLI_00687 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COKDBBLI_00688 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
COKDBBLI_00689 1.5e-56 ftsL D Cell division protein FtsL
COKDBBLI_00690 9.4e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COKDBBLI_00691 1.5e-76 mraZ K Belongs to the MraZ family
COKDBBLI_00692 6.6e-57
COKDBBLI_00693 1.2e-10 S Protein of unknown function (DUF4044)
COKDBBLI_00694 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
COKDBBLI_00695 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COKDBBLI_00696 2.4e-161 rrmA 2.1.1.187 H Methyltransferase
COKDBBLI_00697 1.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
COKDBBLI_00703 4.7e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COKDBBLI_00704 8.1e-190 L PFAM Integrase catalytic region
COKDBBLI_00705 1.1e-24 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
COKDBBLI_00706 1.7e-145 XK27_02985 S Cof-like hydrolase
COKDBBLI_00707 3.5e-79 K Transcriptional regulator
COKDBBLI_00708 0.0 oatA I Acyltransferase
COKDBBLI_00709 1.9e-52
COKDBBLI_00710 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COKDBBLI_00711 4.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COKDBBLI_00712 1e-122 ybbR S YbbR-like protein
COKDBBLI_00713 7.2e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COKDBBLI_00714 8.2e-249 fucP G Major Facilitator Superfamily
COKDBBLI_00715 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
COKDBBLI_00716 7.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COKDBBLI_00717 7.3e-169 murB 1.3.1.98 M Cell wall formation
COKDBBLI_00718 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
COKDBBLI_00719 2.9e-75 S PAS domain
COKDBBLI_00720 3e-87 K Acetyltransferase (GNAT) domain
COKDBBLI_00721 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
COKDBBLI_00722 4.9e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
COKDBBLI_00723 1.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COKDBBLI_00724 1.8e-104 yxjI
COKDBBLI_00725 3.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COKDBBLI_00726 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COKDBBLI_00727 1.5e-146 est 3.1.1.1 S Serine aminopeptidase, S33
COKDBBLI_00728 1.8e-34 secG U Preprotein translocase
COKDBBLI_00729 5.3e-292 clcA P chloride
COKDBBLI_00730 1.6e-247 yifK E Amino acid permease
COKDBBLI_00731 3.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COKDBBLI_00732 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COKDBBLI_00733 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
COKDBBLI_00734 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COKDBBLI_00736 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COKDBBLI_00737 5.7e-242 glpT G Major Facilitator Superfamily
COKDBBLI_00738 8.8e-15
COKDBBLI_00740 3.1e-170 whiA K May be required for sporulation
COKDBBLI_00741 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
COKDBBLI_00742 2.7e-160 rapZ S Displays ATPase and GTPase activities
COKDBBLI_00743 1.1e-245 steT E amino acid
COKDBBLI_00744 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COKDBBLI_00745 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COKDBBLI_00746 6.9e-14
COKDBBLI_00747 2.3e-116 yfbR S HD containing hydrolase-like enzyme
COKDBBLI_00748 2.2e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
COKDBBLI_00749 4.5e-230 ndh 1.6.99.3 C NADH dehydrogenase
COKDBBLI_00750 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
COKDBBLI_00751 1.7e-307 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
COKDBBLI_00752 3.1e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
COKDBBLI_00753 3.6e-271 cydA 1.10.3.14 C ubiquinol oxidase
COKDBBLI_00754 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COKDBBLI_00755 1.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COKDBBLI_00756 1.2e-211 iscS2 2.8.1.7 E Aminotransferase class V
COKDBBLI_00757 1.6e-238 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COKDBBLI_00758 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COKDBBLI_00759 6.9e-292 gadC E amino acid
COKDBBLI_00760 1.1e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
COKDBBLI_00761 4.3e-286 gadC E amino acid
COKDBBLI_00762 3.8e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
COKDBBLI_00763 1.4e-235 pbuG S permease
COKDBBLI_00764 4.9e-262 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
COKDBBLI_00765 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
COKDBBLI_00766 2.6e-135 S Belongs to the UPF0246 family
COKDBBLI_00767 1.2e-137 S Membrane
COKDBBLI_00768 3.1e-74 4.4.1.5 E Glyoxalase
COKDBBLI_00769 2e-21
COKDBBLI_00770 2.5e-86 yueI S Protein of unknown function (DUF1694)
COKDBBLI_00771 1.2e-236 rarA L recombination factor protein RarA
COKDBBLI_00772 4.4e-46
COKDBBLI_00773 4.3e-83 usp6 T universal stress protein
COKDBBLI_00774 1.2e-205 araR K Transcriptional regulator
COKDBBLI_00775 7.3e-155 ytbE 1.1.1.346 S Aldo keto reductase
COKDBBLI_00776 1.7e-91 maa 2.3.1.79 S Maltose O-acetyltransferase
COKDBBLI_00777 4.8e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
COKDBBLI_00778 2e-137 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
COKDBBLI_00779 0.0 araB 2.7.1.16 G carbohydrate kinase FGGY
COKDBBLI_00780 1.7e-260 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
COKDBBLI_00783 1.7e-265 S Uncharacterized protein conserved in bacteria (DUF2252)
COKDBBLI_00784 6.8e-292 L PFAM plasmid pRiA4b ORF-3 family protein
COKDBBLI_00785 2.2e-165 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
COKDBBLI_00786 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COKDBBLI_00787 1.2e-160 mleR K LysR family
COKDBBLI_00788 2.7e-307 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
COKDBBLI_00789 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COKDBBLI_00790 2.4e-267 frdC 1.3.5.4 C FAD binding domain
COKDBBLI_00791 3.7e-252 yflS P Sodium:sulfate symporter transmembrane region
COKDBBLI_00792 1.8e-156 mleR K LysR family
COKDBBLI_00793 4e-251 yjjP S Putative threonine/serine exporter
COKDBBLI_00794 1.9e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
COKDBBLI_00795 4.5e-283 emrY EGP Major facilitator Superfamily
COKDBBLI_00796 2.2e-187 I Alpha beta
COKDBBLI_00797 5.9e-91 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
COKDBBLI_00798 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COKDBBLI_00800 2.6e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
COKDBBLI_00801 1.3e-120 S Domain of unknown function (DUF4811)
COKDBBLI_00802 4.7e-269 lmrB EGP Major facilitator Superfamily
COKDBBLI_00803 5.2e-75 merR K MerR HTH family regulatory protein
COKDBBLI_00804 6.1e-55
COKDBBLI_00805 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COKDBBLI_00806 1.5e-214 S CAAX protease self-immunity
COKDBBLI_00807 3.6e-109 glnP P ABC transporter permease
COKDBBLI_00808 5.4e-110 gluC P ABC transporter permease
COKDBBLI_00809 1.7e-151 glnH ET ABC transporter
COKDBBLI_00810 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COKDBBLI_00811 4.7e-82 usp1 T Belongs to the universal stress protein A family
COKDBBLI_00812 7.6e-110 S VIT family
COKDBBLI_00813 5e-117 S membrane
COKDBBLI_00814 9.1e-167 czcD P cation diffusion facilitator family transporter
COKDBBLI_00815 4.8e-125 sirR K iron dependent repressor
COKDBBLI_00816 3.5e-31 cspC K Cold shock protein
COKDBBLI_00818 2.8e-154 P Belongs to the nlpA lipoprotein family
COKDBBLI_00819 3.9e-12
COKDBBLI_00820 2.6e-222 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
COKDBBLI_00821 5.8e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COKDBBLI_00822 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
COKDBBLI_00823 1.7e-176 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COKDBBLI_00824 5.9e-22 S Protein of unknown function (DUF3042)
COKDBBLI_00825 3.4e-67 yqhL P Rhodanese-like protein
COKDBBLI_00826 1.5e-183 glk 2.7.1.2 G Glucokinase
COKDBBLI_00827 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
COKDBBLI_00828 2.7e-112 gluP 3.4.21.105 S Peptidase, S54 family
COKDBBLI_00829 2.9e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COKDBBLI_00830 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COKDBBLI_00831 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
COKDBBLI_00832 0.0 S membrane
COKDBBLI_00833 4.4e-70 yneR S Belongs to the HesB IscA family
COKDBBLI_00834 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COKDBBLI_00835 2.5e-118 udk 2.7.1.48 F Cytidine monophosphokinase
COKDBBLI_00836 4.3e-115 rlpA M PFAM NLP P60 protein
COKDBBLI_00837 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COKDBBLI_00838 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COKDBBLI_00839 6.7e-59 yodB K Transcriptional regulator, HxlR family
COKDBBLI_00840 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
COKDBBLI_00841 4.8e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COKDBBLI_00842 5e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
COKDBBLI_00843 2.9e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COKDBBLI_00844 1.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
COKDBBLI_00845 6.3e-230 V MatE
COKDBBLI_00846 1.9e-267 yjeM E Amino Acid
COKDBBLI_00847 1.2e-277 arlS 2.7.13.3 T Histidine kinase
COKDBBLI_00848 1.5e-121 K response regulator
COKDBBLI_00849 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
COKDBBLI_00850 2.9e-99 yceD S Uncharacterized ACR, COG1399
COKDBBLI_00851 1.6e-213 ylbM S Belongs to the UPF0348 family
COKDBBLI_00852 3.9e-136 yqeM Q Methyltransferase
COKDBBLI_00853 6.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COKDBBLI_00854 3.5e-114 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
COKDBBLI_00855 2.4e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COKDBBLI_00856 1.9e-47 yhbY J RNA-binding protein
COKDBBLI_00857 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
COKDBBLI_00858 4.8e-96 yqeG S HAD phosphatase, family IIIA
COKDBBLI_00859 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COKDBBLI_00860 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COKDBBLI_00861 2.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COKDBBLI_00862 3.6e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COKDBBLI_00863 1.2e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
COKDBBLI_00864 8.6e-207 yacL S domain protein
COKDBBLI_00865 1.1e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COKDBBLI_00866 3.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
COKDBBLI_00867 7.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
COKDBBLI_00868 7.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COKDBBLI_00869 6.2e-265 pepC 3.4.22.40 E Peptidase C1-like family
COKDBBLI_00870 2.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
COKDBBLI_00871 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COKDBBLI_00872 1.1e-119 tcyB E ABC transporter
COKDBBLI_00873 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COKDBBLI_00874 1.1e-169 I alpha/beta hydrolase fold
COKDBBLI_00875 3.5e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COKDBBLI_00876 0.0 S Bacterial membrane protein, YfhO
COKDBBLI_00877 1.9e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
COKDBBLI_00878 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
COKDBBLI_00880 3.3e-85 ydcK S Belongs to the SprT family
COKDBBLI_00881 0.0 yhgF K Tex-like protein N-terminal domain protein
COKDBBLI_00882 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COKDBBLI_00883 4.5e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COKDBBLI_00884 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
COKDBBLI_00885 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
COKDBBLI_00886 3e-301 aspT P Predicted Permease Membrane Region
COKDBBLI_00887 1.5e-250 EGP Major facilitator Superfamily
COKDBBLI_00888 2.5e-110
COKDBBLI_00891 2e-149 yjjH S Calcineurin-like phosphoesterase
COKDBBLI_00892 1.3e-263 dtpT U amino acid peptide transporter
COKDBBLI_00893 2.4e-18
COKDBBLI_00895 5.8e-74 yqiG C Oxidoreductase
COKDBBLI_00896 1.1e-61 yqiG C Oxidoreductase
COKDBBLI_00897 7.9e-61 S macrophage migration inhibitory factor
COKDBBLI_00898 1.2e-42 K HxlR-like helix-turn-helix
COKDBBLI_00899 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COKDBBLI_00902 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COKDBBLI_00903 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COKDBBLI_00904 2.5e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COKDBBLI_00905 4.5e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COKDBBLI_00906 5.3e-198 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COKDBBLI_00907 7.9e-31 yajC U Preprotein translocase
COKDBBLI_00908 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
COKDBBLI_00909 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COKDBBLI_00910 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COKDBBLI_00911 1.2e-42 yrzL S Belongs to the UPF0297 family
COKDBBLI_00912 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COKDBBLI_00913 6.1e-48 yrzB S Belongs to the UPF0473 family
COKDBBLI_00914 1e-85 cvpA S Colicin V production protein
COKDBBLI_00915 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COKDBBLI_00916 6.1e-54 trxA O Belongs to the thioredoxin family
COKDBBLI_00917 1.3e-96 yslB S Protein of unknown function (DUF2507)
COKDBBLI_00918 5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COKDBBLI_00919 2.4e-104 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COKDBBLI_00920 2e-94 S Phosphoesterase
COKDBBLI_00921 3.6e-76 ykuL S (CBS) domain
COKDBBLI_00922 1e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
COKDBBLI_00923 1.5e-147 ykuT M mechanosensitive ion channel
COKDBBLI_00924 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COKDBBLI_00925 2e-21
COKDBBLI_00926 1.2e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COKDBBLI_00927 4.5e-183 ccpA K catabolite control protein A
COKDBBLI_00928 1.1e-134
COKDBBLI_00929 1e-131 yebC K Transcriptional regulatory protein
COKDBBLI_00930 4.3e-183 comGA NU Type II IV secretion system protein
COKDBBLI_00931 1.1e-179 comGB NU type II secretion system
COKDBBLI_00932 5.4e-47 comGC U competence protein ComGC
COKDBBLI_00933 1.4e-77 NU general secretion pathway protein
COKDBBLI_00934 5.8e-43
COKDBBLI_00935 5.4e-69
COKDBBLI_00936 2.9e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
COKDBBLI_00937 3.4e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COKDBBLI_00938 2.9e-37 S Calcineurin-like phosphoesterase
COKDBBLI_00939 4.4e-100 yutD S Protein of unknown function (DUF1027)
COKDBBLI_00940 1.4e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COKDBBLI_00941 1.4e-113 S Protein of unknown function (DUF1461)
COKDBBLI_00942 1.6e-109 dedA S SNARE-like domain protein
COKDBBLI_00943 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COKDBBLI_00944 3.6e-216 ecsB U ABC transporter
COKDBBLI_00945 1.3e-136 ecsA V ABC transporter, ATP-binding protein
COKDBBLI_00946 3.2e-77 hit FG histidine triad
COKDBBLI_00948 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COKDBBLI_00949 0.0 L AAA domain
COKDBBLI_00950 1.3e-210 yhaO L Ser Thr phosphatase family protein
COKDBBLI_00951 3.6e-37 yheA S Belongs to the UPF0342 family
COKDBBLI_00952 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COKDBBLI_00953 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
COKDBBLI_00954 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COKDBBLI_00955 9.3e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COKDBBLI_00957 3.3e-40
COKDBBLI_00958 1.4e-43
COKDBBLI_00959 1.8e-212 folP 2.5.1.15 H dihydropteroate synthase
COKDBBLI_00960 2.9e-102 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
COKDBBLI_00961 1.6e-222 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COKDBBLI_00962 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
COKDBBLI_00963 2.4e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
COKDBBLI_00964 1.2e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COKDBBLI_00965 3.8e-69
COKDBBLI_00967 1.9e-43
COKDBBLI_00968 8.3e-117 S CAAX protease self-immunity
COKDBBLI_00969 2.1e-32
COKDBBLI_00970 3.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COKDBBLI_00971 8.2e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
COKDBBLI_00972 2.2e-113
COKDBBLI_00973 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
COKDBBLI_00974 3e-174 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COKDBBLI_00975 9.5e-86 uspA T Belongs to the universal stress protein A family
COKDBBLI_00976 3.7e-276 pepV 3.5.1.18 E dipeptidase PepV
COKDBBLI_00977 7.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COKDBBLI_00978 3.8e-256 ytgP S Polysaccharide biosynthesis protein
COKDBBLI_00979 1.4e-40
COKDBBLI_00980 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COKDBBLI_00981 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COKDBBLI_00982 8.4e-96 tag 3.2.2.20 L glycosylase
COKDBBLI_00983 8.4e-35 fhaB M Rib/alpha-like repeat
COKDBBLI_00984 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COKDBBLI_00985 1.1e-194 XK27_09615 S reductase
COKDBBLI_00986 5.4e-101 nqr 1.5.1.36 S reductase
COKDBBLI_00987 6.9e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COKDBBLI_00988 1.9e-178 K Transcriptional regulator, LacI family
COKDBBLI_00989 1.4e-259 G Major Facilitator
COKDBBLI_00990 2e-266 G Major Facilitator
COKDBBLI_00991 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
COKDBBLI_00992 1.1e-275 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
COKDBBLI_00993 1.1e-262 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
COKDBBLI_00994 2.4e-265 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
COKDBBLI_00995 1.7e-69
COKDBBLI_00996 6.2e-32 S ABC-type transport system involved in multi-copper enzyme maturation permease component
COKDBBLI_00997 1e-74 V ATPases associated with a variety of cellular activities
COKDBBLI_00998 3.3e-107 K Transcriptional regulator, TetR family
COKDBBLI_00999 9.3e-248 steT_1 E amino acid
COKDBBLI_01000 6.6e-136 puuD S peptidase C26
COKDBBLI_01002 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COKDBBLI_01003 2.7e-87
COKDBBLI_01004 4.5e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COKDBBLI_01005 3.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COKDBBLI_01006 7.1e-261 nox C NADH oxidase
COKDBBLI_01007 4.3e-86 hmpT S ECF-type riboflavin transporter, S component
COKDBBLI_01008 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
COKDBBLI_01009 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
COKDBBLI_01010 5.9e-168 yvgN C Aldo keto reductase
COKDBBLI_01011 7.8e-137 puuD S peptidase C26
COKDBBLI_01012 5.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
COKDBBLI_01013 2.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
COKDBBLI_01014 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
COKDBBLI_01015 1.1e-256 malT G Major Facilitator
COKDBBLI_01016 1.2e-211 phbA 2.3.1.9 I Belongs to the thiolase family
COKDBBLI_01017 4.3e-172 malR K Transcriptional regulator, LacI family
COKDBBLI_01018 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
COKDBBLI_01019 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COKDBBLI_01020 7.9e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COKDBBLI_01021 1.7e-105 wecD3 K PFAM GCN5-related N-acetyltransferase
COKDBBLI_01023 2.1e-165 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
COKDBBLI_01024 0.0 clpL O associated with various cellular activities
COKDBBLI_01025 2.7e-32
COKDBBLI_01026 8.9e-215 patA 2.6.1.1 E Aminotransferase
COKDBBLI_01027 7.3e-178 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COKDBBLI_01028 8.5e-75 osmC O OsmC-like protein
COKDBBLI_01030 1.3e-245 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
COKDBBLI_01034 1.1e-136 K LytTr DNA-binding domain
COKDBBLI_01035 2.1e-135 2.7.13.3 T GHKL domain
COKDBBLI_01036 2e-10 2.7.13.3 T GHKL domain
COKDBBLI_01039 2.9e-257 S Putative peptidoglycan binding domain
COKDBBLI_01040 1.3e-37
COKDBBLI_01042 2.6e-217 bacI V MacB-like periplasmic core domain
COKDBBLI_01043 4.4e-129 V ABC transporter
COKDBBLI_01044 4.4e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COKDBBLI_01045 2e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
COKDBBLI_01046 6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COKDBBLI_01047 1.2e-148 E Glyoxalase-like domain
COKDBBLI_01048 7.5e-155 glcU U sugar transport
COKDBBLI_01049 2.5e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
COKDBBLI_01050 2.2e-96 S reductase
COKDBBLI_01051 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COKDBBLI_01052 6e-21 ABC-SBP S ABC transporter
COKDBBLI_01053 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
COKDBBLI_01054 1.9e-218 htrA 3.4.21.107 O serine protease
COKDBBLI_01055 2.3e-153 vicX 3.1.26.11 S domain protein
COKDBBLI_01056 5.4e-150 yycI S YycH protein
COKDBBLI_01057 1.5e-247 yycH S YycH protein
COKDBBLI_01058 0.0 vicK 2.7.13.3 T Histidine kinase
COKDBBLI_01059 5.2e-130 K response regulator
COKDBBLI_01061 2.1e-163 lmrA 3.6.3.44 V ABC transporter
COKDBBLI_01062 3.7e-67 lmrA 3.6.3.44 V ABC transporter
COKDBBLI_01063 5.6e-74 K helix_turn_helix multiple antibiotic resistance protein
COKDBBLI_01065 7.9e-124 Z012_01130 S Fic/DOC family
COKDBBLI_01066 1.1e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
COKDBBLI_01067 4.8e-54
COKDBBLI_01068 2.2e-205 yttB EGP Major facilitator Superfamily
COKDBBLI_01069 6.9e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COKDBBLI_01070 2e-74 rplI J Binds to the 23S rRNA
COKDBBLI_01071 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
COKDBBLI_01072 4.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COKDBBLI_01073 9.1e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COKDBBLI_01074 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
COKDBBLI_01075 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COKDBBLI_01076 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COKDBBLI_01077 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COKDBBLI_01078 1.7e-34 yaaA S S4 domain protein YaaA
COKDBBLI_01079 4.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COKDBBLI_01080 5.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COKDBBLI_01081 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
COKDBBLI_01082 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COKDBBLI_01083 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COKDBBLI_01084 6.4e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
COKDBBLI_01085 1.1e-204 hsdM 2.1.1.72 V type I restriction-modification system
COKDBBLI_01086 1.9e-48 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain protein
COKDBBLI_01087 7.4e-132 L Belongs to the 'phage' integrase family
COKDBBLI_01088 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
COKDBBLI_01090 7.5e-46 hsdS 3.1.21.3 V PFAM restriction modification system DNA specificity domain
COKDBBLI_01093 1e-131 jag S R3H domain protein
COKDBBLI_01094 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COKDBBLI_01095 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COKDBBLI_01096 0.0 asnB 6.3.5.4 E Asparagine synthase
COKDBBLI_01097 6.4e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COKDBBLI_01098 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
COKDBBLI_01099 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COKDBBLI_01100 4.8e-90 2.3.1.183 M Acetyltransferase GNAT family
COKDBBLI_01101 9.1e-161 S reductase
COKDBBLI_01103 1.9e-07 yiiE S Protein of unknown function (DUF1211)
COKDBBLI_01105 9.2e-36 K LysR substrate binding domain
COKDBBLI_01107 2.4e-21 S amidohydrolase
COKDBBLI_01108 6.2e-227 S amidohydrolase
COKDBBLI_01110 4e-36 blpT
COKDBBLI_01111 6.5e-45 K LytTr DNA-binding domain
COKDBBLI_01112 2.3e-16 T GHKL domain
COKDBBLI_01113 1.1e-98 L Helix-turn-helix domain
COKDBBLI_01114 5.3e-161 L hmm pf00665
COKDBBLI_01115 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
COKDBBLI_01116 4.4e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
COKDBBLI_01117 9.2e-215 L Integrase core domain
COKDBBLI_01118 2.1e-126 O Bacterial dnaA protein
COKDBBLI_01120 4.1e-65 T Toxin-antitoxin system, toxin component, MazF family
COKDBBLI_01121 1e-37
COKDBBLI_01123 0.0 snf 2.7.11.1 KL domain protein
COKDBBLI_01124 3.1e-144 ywqE 3.1.3.48 GM PHP domain protein
COKDBBLI_01125 1.8e-209 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
COKDBBLI_01126 0.0 sbcC L Putative exonuclease SbcCD, C subunit
COKDBBLI_01127 6e-91 L nuclease
COKDBBLI_01128 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
COKDBBLI_01129 8.1e-70
COKDBBLI_01130 6.8e-104 fic D Fic/DOC family
COKDBBLI_01131 1.7e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COKDBBLI_01132 4.6e-149 3.1.3.73 G Belongs to the phosphoglycerate mutase family
COKDBBLI_01133 1.7e-29
COKDBBLI_01134 3e-96 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COKDBBLI_01135 3.5e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COKDBBLI_01136 1.7e-137 cdsA 2.7.7.41 I Belongs to the CDS family
COKDBBLI_01137 1.8e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
COKDBBLI_01138 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COKDBBLI_01139 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COKDBBLI_01140 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
COKDBBLI_01141 1.2e-214 nusA K Participates in both transcription termination and antitermination
COKDBBLI_01142 2.3e-44 ylxR K Protein of unknown function (DUF448)
COKDBBLI_01143 4.5e-49 ylxQ J ribosomal protein
COKDBBLI_01144 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COKDBBLI_01145 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COKDBBLI_01146 2.6e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COKDBBLI_01147 2.2e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COKDBBLI_01148 2.6e-64
COKDBBLI_01149 1.2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COKDBBLI_01150 4.6e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COKDBBLI_01151 0.0 dnaK O Heat shock 70 kDa protein
COKDBBLI_01152 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COKDBBLI_01153 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COKDBBLI_01154 1.7e-273 pipD E Dipeptidase
COKDBBLI_01155 5.6e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
COKDBBLI_01156 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COKDBBLI_01158 7.5e-58
COKDBBLI_01159 4.8e-179 prmA J Ribosomal protein L11 methyltransferase
COKDBBLI_01160 2.1e-126 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COKDBBLI_01161 1e-51
COKDBBLI_01162 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COKDBBLI_01163 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COKDBBLI_01164 3e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COKDBBLI_01165 2.5e-186 yegS 2.7.1.107 G Lipid kinase
COKDBBLI_01166 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COKDBBLI_01167 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COKDBBLI_01168 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COKDBBLI_01169 1.2e-202 camS S sex pheromone
COKDBBLI_01170 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COKDBBLI_01171 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
COKDBBLI_01172 5.1e-212 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COKDBBLI_01173 3.5e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COKDBBLI_01174 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
COKDBBLI_01175 2.1e-140 IQ reductase
COKDBBLI_01176 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
COKDBBLI_01177 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COKDBBLI_01178 1.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COKDBBLI_01179 1.3e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COKDBBLI_01180 2.9e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COKDBBLI_01181 5.2e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COKDBBLI_01182 1.1e-62 rplQ J Ribosomal protein L17
COKDBBLI_01183 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COKDBBLI_01184 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COKDBBLI_01185 3.6e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COKDBBLI_01186 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
COKDBBLI_01187 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COKDBBLI_01188 1.8e-124 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COKDBBLI_01189 4.4e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COKDBBLI_01190 8.9e-64 rplO J Binds to the 23S rRNA
COKDBBLI_01191 2.9e-24 rpmD J Ribosomal protein L30
COKDBBLI_01192 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COKDBBLI_01193 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COKDBBLI_01194 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COKDBBLI_01195 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COKDBBLI_01196 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COKDBBLI_01197 7.5e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COKDBBLI_01198 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COKDBBLI_01199 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COKDBBLI_01200 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
COKDBBLI_01201 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COKDBBLI_01202 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COKDBBLI_01203 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COKDBBLI_01204 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COKDBBLI_01205 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COKDBBLI_01206 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COKDBBLI_01207 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
COKDBBLI_01208 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COKDBBLI_01209 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
COKDBBLI_01210 2.7e-149 lysA2 M Glycosyl hydrolases family 25
COKDBBLI_01211 6e-34 S Bacteriophage holin of superfamily 6 (Holin_LLH)
COKDBBLI_01218 7.3e-40 GT2,GT4 LM gp58-like protein
COKDBBLI_01219 1.6e-142 ydhO 3.4.14.13 M Prophage endopeptidase tail
COKDBBLI_01220 6.3e-85 S Phage tail protein
COKDBBLI_01221 3e-68 M Phage tail tape measure protein TP901
COKDBBLI_01222 3e-175 M Phage tail tape measure protein TP901
COKDBBLI_01223 1.5e-13 S Phage tail assembly chaperone proteins, TAC
COKDBBLI_01224 2.4e-78 S Phage tail tube protein
COKDBBLI_01225 1.5e-19 S Protein of unknown function (DUF806)
COKDBBLI_01226 8.6e-35 S exonuclease activity
COKDBBLI_01227 3.8e-10 S Phage head-tail joining protein
COKDBBLI_01228 3.9e-49 S Phage gp6-like head-tail connector protein
COKDBBLI_01229 4.7e-171 S Phage capsid family
COKDBBLI_01230 3.3e-66 S Clp protease
COKDBBLI_01231 3.5e-195 S Phage portal protein
COKDBBLI_01232 4.3e-288 S overlaps another CDS with the same product name
COKDBBLI_01233 1.7e-65 L Phage terminase, small subunit
COKDBBLI_01234 2.8e-67 L HNH nucleases
COKDBBLI_01235 1.6e-08
COKDBBLI_01238 5.5e-83 arpU S Phage transcriptional regulator, ArpU family
COKDBBLI_01242 2.1e-15
COKDBBLI_01246 3.4e-127
COKDBBLI_01248 8.2e-70
COKDBBLI_01250 7.1e-49 L Transposase, IS116 IS110 IS902 family
COKDBBLI_01252 1.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COKDBBLI_01253 4.3e-267 yfnA E amino acid
COKDBBLI_01254 3.5e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COKDBBLI_01255 4e-41 1.3.5.4 S FMN binding
COKDBBLI_01256 1.3e-221 norA EGP Major facilitator Superfamily
COKDBBLI_01257 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
COKDBBLI_01258 5.9e-152 metQ1 P Belongs to the nlpA lipoprotein family
COKDBBLI_01259 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COKDBBLI_01260 4.1e-103 metI P ABC transporter permease
COKDBBLI_01261 6.3e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COKDBBLI_01262 5.7e-29 clcA P chloride
COKDBBLI_01263 8e-100 clcA P chloride
COKDBBLI_01264 2.8e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
COKDBBLI_01265 4.5e-104 proW P ABC transporter, permease protein
COKDBBLI_01266 7.2e-141 proV E ABC transporter, ATP-binding protein
COKDBBLI_01267 1.6e-109 proWZ P ABC transporter permease
COKDBBLI_01268 4.6e-163 proX M ABC transporter, substrate-binding protein, QAT family
COKDBBLI_01269 5.8e-74 K Transcriptional regulator
COKDBBLI_01270 3.7e-84 L PFAM transposase IS200-family protein
COKDBBLI_01271 5.2e-215 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
COKDBBLI_01272 7.2e-309 cadA P P-type ATPase
COKDBBLI_01273 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
COKDBBLI_01274 1.7e-125
COKDBBLI_01275 3.3e-55 S Sugar efflux transporter for intercellular exchange
COKDBBLI_01276 1.6e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
COKDBBLI_01278 0.0 L Helicase C-terminal domain protein
COKDBBLI_01279 1.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
COKDBBLI_01280 5.7e-180 S Aldo keto reductase
COKDBBLI_01281 5.1e-162 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COKDBBLI_01282 7.8e-157 ytbE 1.1.1.346 S Aldo keto reductase
COKDBBLI_01283 1.4e-124 K response regulator
COKDBBLI_01284 6.5e-179 T PhoQ Sensor
COKDBBLI_01285 3.7e-134 macB2 V ABC transporter, ATP-binding protein
COKDBBLI_01286 0.0 ysaB V FtsX-like permease family
COKDBBLI_01287 3.6e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
COKDBBLI_01288 1.9e-164 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COKDBBLI_01289 6.1e-30 K helix_turn_helix, mercury resistance
COKDBBLI_01290 1.1e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COKDBBLI_01291 9e-196 EGP Major facilitator Superfamily
COKDBBLI_01292 1.3e-90 ymdB S Macro domain protein
COKDBBLI_01293 1e-105 K Helix-turn-helix XRE-family like proteins
COKDBBLI_01294 0.0 pepO 3.4.24.71 O Peptidase family M13
COKDBBLI_01295 2.3e-47
COKDBBLI_01296 1.5e-231 S Putative metallopeptidase domain
COKDBBLI_01297 7e-201 3.1.3.1 S associated with various cellular activities
COKDBBLI_01298 2.6e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
COKDBBLI_01299 5.9e-64 yeaO S Protein of unknown function, DUF488
COKDBBLI_01301 6e-115 yrkL S Flavodoxin-like fold
COKDBBLI_01302 3.6e-54
COKDBBLI_01303 6.6e-19 S Domain of unknown function (DUF4767)
COKDBBLI_01304 2.9e-55 2.1.1.72 D peptidase
COKDBBLI_01305 2.6e-58 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COKDBBLI_01306 3.1e-49
COKDBBLI_01307 1e-201 nrnB S DHHA1 domain
COKDBBLI_01308 2.3e-229 S Uncharacterized protein conserved in bacteria (DUF2325)
COKDBBLI_01309 3e-246 brnQ U Component of the transport system for branched-chain amino acids
COKDBBLI_01310 9.9e-106 NU mannosyl-glycoprotein
COKDBBLI_01311 8.7e-69 S Putative ABC-transporter type IV
COKDBBLI_01312 3.3e-33 S Putative ABC-transporter type IV
COKDBBLI_01313 6e-272 S ABC transporter, ATP-binding protein
COKDBBLI_01314 8.6e-135
COKDBBLI_01316 1.3e-243 ydaM M Glycosyl transferase
COKDBBLI_01317 1.2e-224 G Glycosyl hydrolases family 8
COKDBBLI_01318 7.1e-141 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
COKDBBLI_01319 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
COKDBBLI_01320 6.5e-238 ktrB P Potassium uptake protein
COKDBBLI_01321 6.9e-116 ktrA P domain protein
COKDBBLI_01322 1.1e-79 Q Methyltransferase
COKDBBLI_01323 2.2e-230 mntH P H( )-stimulated, divalent metal cation uptake system
COKDBBLI_01324 8.6e-181 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
COKDBBLI_01325 9.7e-161 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COKDBBLI_01326 1.1e-24 S NADPH-dependent FMN reductase
COKDBBLI_01327 3.6e-172 MA20_14895 S Conserved hypothetical protein 698
COKDBBLI_01328 6.8e-167 L transposase, IS605 OrfB family
COKDBBLI_01329 1.6e-110 I alpha/beta hydrolase fold
COKDBBLI_01330 1.8e-82 lsa S ABC transporter
COKDBBLI_01331 7.1e-27 lsa S ABC transporter
COKDBBLI_01332 2.5e-172 yfeX P Peroxidase
COKDBBLI_01333 4.5e-272 arcD S C4-dicarboxylate anaerobic carrier
COKDBBLI_01334 2.1e-257 ytjP 3.5.1.18 E Dipeptidase
COKDBBLI_01335 2.2e-57 ubiE_1 Q Methyltransferase
COKDBBLI_01336 3.7e-152 nikA E Bacterial extracellular solute-binding proteins, family 5 Middle
COKDBBLI_01337 1e-48 nikB P Binding-protein-dependent transport system inner membrane component
COKDBBLI_01338 5.7e-56 EP N-terminal TM domain of oligopeptide transport permease C
COKDBBLI_01340 1.7e-15 arpU S Phage transcriptional regulator, ArpU family
COKDBBLI_01343 1.3e-25
COKDBBLI_01348 3.9e-22
COKDBBLI_01349 1.1e-80 Q DNA (cytosine-5-)-methyltransferase activity
COKDBBLI_01353 7e-16
COKDBBLI_01358 1.3e-40 S ORF6C domain
COKDBBLI_01361 3.6e-25
COKDBBLI_01362 2.4e-20 L Psort location Cytoplasmic, score
COKDBBLI_01363 1.3e-66 S PDDEXK-like domain of unknown function (DUF3799)
COKDBBLI_01364 5.5e-135 recT L RecT family
COKDBBLI_01368 4.2e-32
COKDBBLI_01369 1.3e-14 K Cro/C1-type HTH DNA-binding domain
COKDBBLI_01370 1.5e-22
COKDBBLI_01376 9.3e-24 xre K Helix-turn-helix XRE-family like proteins
COKDBBLI_01378 6.4e-13
COKDBBLI_01379 5e-88 J Domain of unknown function (DUF4041)
COKDBBLI_01380 4.1e-92 L Belongs to the 'phage' integrase family
COKDBBLI_01381 1.8e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COKDBBLI_01382 4.7e-117 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
COKDBBLI_01383 1.5e-228 clcA_2 P Chloride transporter, ClC family
COKDBBLI_01384 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
COKDBBLI_01385 2.2e-111 lssY 3.6.1.27 I Acid phosphatase homologues
COKDBBLI_01396 5.3e-57 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
COKDBBLI_01397 8.6e-128 S Tetratricopeptide repeat
COKDBBLI_01398 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COKDBBLI_01399 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COKDBBLI_01400 4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COKDBBLI_01401 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
COKDBBLI_01402 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
COKDBBLI_01403 4.9e-08
COKDBBLI_01404 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COKDBBLI_01405 3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COKDBBLI_01406 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COKDBBLI_01407 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COKDBBLI_01408 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
COKDBBLI_01409 1.6e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COKDBBLI_01410 8.7e-89
COKDBBLI_01412 2.5e-126 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COKDBBLI_01413 3.1e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
COKDBBLI_01414 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COKDBBLI_01415 6.6e-35 ynzC S UPF0291 protein
COKDBBLI_01416 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
COKDBBLI_01417 1.6e-117 plsC 2.3.1.51 I Acyltransferase
COKDBBLI_01418 3.2e-141 yabB 2.1.1.223 L Methyltransferase small domain
COKDBBLI_01419 5.4e-49 yazA L GIY-YIG catalytic domain protein
COKDBBLI_01420 4.1e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COKDBBLI_01421 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
COKDBBLI_01422 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COKDBBLI_01423 1.3e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COKDBBLI_01424 3.7e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COKDBBLI_01425 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
COKDBBLI_01426 4.4e-86 ygfC K transcriptional regulator (TetR family)
COKDBBLI_01427 1.6e-170 hrtB V ABC transporter permease
COKDBBLI_01428 3.9e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
COKDBBLI_01429 0.0 yhcA V ABC transporter, ATP-binding protein
COKDBBLI_01430 6.6e-37
COKDBBLI_01431 4.1e-50 czrA K Transcriptional regulator, ArsR family
COKDBBLI_01432 2.1e-241 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COKDBBLI_01433 8.7e-173 scrR K Transcriptional regulator, LacI family
COKDBBLI_01434 1e-24
COKDBBLI_01435 1.6e-106
COKDBBLI_01436 1.2e-214 yttB EGP Major facilitator Superfamily
COKDBBLI_01437 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
COKDBBLI_01438 1.3e-87
COKDBBLI_01439 6.6e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
COKDBBLI_01440 1.1e-256 S Putative peptidoglycan binding domain
COKDBBLI_01441 1.1e-13
COKDBBLI_01442 3.2e-121 yciB M ErfK YbiS YcfS YnhG
COKDBBLI_01444 3.9e-99
COKDBBLI_01445 8.7e-218 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COKDBBLI_01446 8.5e-124 S Alpha beta hydrolase
COKDBBLI_01447 4.4e-208 gldA 1.1.1.6 C dehydrogenase
COKDBBLI_01448 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COKDBBLI_01449 6.1e-25
COKDBBLI_01450 0.0 G Peptidase_C39 like family
COKDBBLI_01451 0.0 2.7.7.6 M Peptidase family M23
COKDBBLI_01452 4.2e-118 rfbP 2.7.8.6 M Bacterial sugar transferase
COKDBBLI_01453 1e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
COKDBBLI_01454 1.3e-145 cps1D M Domain of unknown function (DUF4422)
COKDBBLI_01455 5.9e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
COKDBBLI_01456 1.9e-30
COKDBBLI_01457 1.6e-32 S Protein of unknown function (DUF2922)
COKDBBLI_01458 1.5e-153 yihY S Belongs to the UPF0761 family
COKDBBLI_01459 5.8e-280 yjeM E Amino Acid
COKDBBLI_01460 7.3e-256 E Arginine ornithine antiporter
COKDBBLI_01461 1.7e-220 arcT 2.6.1.1 E Aminotransferase
COKDBBLI_01462 2.9e-167 map 3.4.11.18 E Methionine Aminopeptidase
COKDBBLI_01463 6.1e-79 fld C Flavodoxin
COKDBBLI_01464 1.9e-74 gtcA S Teichoic acid glycosylation protein
COKDBBLI_01465 7.1e-56
COKDBBLI_01466 9.9e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COKDBBLI_01468 7.7e-228 yfmL L DEAD DEAH box helicase
COKDBBLI_01469 1.9e-189 mocA S Oxidoreductase
COKDBBLI_01470 9.1e-62 S Domain of unknown function (DUF4828)
COKDBBLI_01471 2e-103 yvdD 3.2.2.10 S Belongs to the LOG family
COKDBBLI_01472 1.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
COKDBBLI_01473 4.2e-294 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
COKDBBLI_01474 1.3e-190 S Protein of unknown function (DUF3114)
COKDBBLI_01475 3.3e-77 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
COKDBBLI_01476 8.4e-120 ybhL S Belongs to the BI1 family
COKDBBLI_01477 5.5e-21
COKDBBLI_01478 3.1e-72 K LytTr DNA-binding domain
COKDBBLI_01479 2.1e-68 S Protein of unknown function (DUF3021)
COKDBBLI_01480 3.2e-135 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
COKDBBLI_01481 1.9e-18 XK27_00915 C Luciferase-like monooxygenase
COKDBBLI_01482 2.8e-27 XK27_00915 C Luciferase-like monooxygenase
COKDBBLI_01483 4e-116 pnb C nitroreductase
COKDBBLI_01484 7.1e-38
COKDBBLI_01485 3e-243 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
COKDBBLI_01486 2.2e-87 3.6.4.12 S PD-(D/E)XK nuclease family transposase
COKDBBLI_01488 1.9e-47
COKDBBLI_01489 5.7e-155 cylA V ABC transporter
COKDBBLI_01490 2.8e-146 cylB V ABC-2 type transporter
COKDBBLI_01491 1.3e-73 K LytTr DNA-binding domain
COKDBBLI_01492 1.2e-59 S Protein of unknown function (DUF3021)
COKDBBLI_01494 1.3e-176 L Plasmid pRiA4b ORF-3-like protein
COKDBBLI_01495 7.8e-71 1.6.5.2 S NADPH-dependent FMN reductase
COKDBBLI_01496 2.8e-53 K Bacterial regulatory proteins, tetR family
COKDBBLI_01497 1.5e-47 V ABC transporter, ATP-binding protein
COKDBBLI_01498 3e-27 V ABC transporter, ATP-binding protein
COKDBBLI_01499 5.8e-54 yqkB S Belongs to the HesB IscA family
COKDBBLI_01500 2.9e-20
COKDBBLI_01501 2e-19
COKDBBLI_01502 3.9e-34
COKDBBLI_01503 5.1e-18 K LytTr DNA-binding domain
COKDBBLI_01504 2.1e-33 S Protein of unknown function (DUF3021)
COKDBBLI_01505 7e-80 1.6.5.2 S NADPH-dependent FMN reductase
COKDBBLI_01506 7.7e-65 K Bacterial regulatory proteins, tetR family
COKDBBLI_01508 2.3e-58
COKDBBLI_01509 2.6e-74 S Metallo-beta-lactamase superfamily
COKDBBLI_01510 5e-52 K Psort location Cytoplasmic, score
COKDBBLI_01511 6.4e-51 yjdF S Protein of unknown function (DUF2992)
COKDBBLI_01512 3.1e-190 L Transposase
COKDBBLI_01513 5.9e-74 5.1.1.13 M Asp/Glu/Hydantoin racemase
COKDBBLI_01514 1.4e-33 5.1.1.13 M Asp/Glu/Hydantoin racemase
COKDBBLI_01515 2.8e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
COKDBBLI_01516 1.7e-111 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
COKDBBLI_01517 1.6e-94 dps P Belongs to the Dps family
COKDBBLI_01518 5.8e-32 copZ C Heavy-metal-associated domain
COKDBBLI_01519 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
COKDBBLI_01520 1.3e-102
COKDBBLI_01521 2e-106 L Bacterial dnaA protein
COKDBBLI_01523 3.5e-174 L Integrase core domain
COKDBBLI_01524 4e-22 L Integrase core domain
COKDBBLI_01525 6.6e-71 L Belongs to the 'phage' integrase family
COKDBBLI_01526 8.1e-260 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
COKDBBLI_01527 7.5e-17
COKDBBLI_01528 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COKDBBLI_01530 1.4e-34 yxiO S Vacuole effluxer Atg22 like
COKDBBLI_01531 2.7e-22 yxiO S Vacuole effluxer Atg22 like
COKDBBLI_01532 1.2e-103 yxiO S Vacuole effluxer Atg22 like
COKDBBLI_01533 4.7e-246 npp S type I phosphodiesterase nucleotide pyrophosphatase
COKDBBLI_01534 1.2e-239 E amino acid
COKDBBLI_01535 6.7e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COKDBBLI_01537 5.1e-220 yxjG_1 E methionine synthase, vitamin-B12 independent
COKDBBLI_01538 1.7e-40 S Cytochrome B5
COKDBBLI_01539 5.4e-09 S Cytochrome B5
COKDBBLI_01540 7e-39 S Cytochrome B5
COKDBBLI_01541 6.4e-38 elaA S Gnat family
COKDBBLI_01542 1.3e-07 elaA S Gnat family
COKDBBLI_01543 3e-10 GM NmrA-like family
COKDBBLI_01544 2.8e-51 hxlR K Transcriptional regulator, HxlR family
COKDBBLI_01545 5.3e-107 XK27_02070 S Nitroreductase family
COKDBBLI_01546 8.7e-78 K Transcriptional regulator, HxlR family
COKDBBLI_01547 1e-227
COKDBBLI_01548 1e-210 EGP Major facilitator Superfamily
COKDBBLI_01549 1.8e-253 pepC 3.4.22.40 E aminopeptidase
COKDBBLI_01550 1.1e-110 ylbE GM NAD dependent epimerase dehydratase family protein
COKDBBLI_01551 0.0 pepN 3.4.11.2 E aminopeptidase
COKDBBLI_01552 1.3e-88 folT S ECF transporter, substrate-specific component
COKDBBLI_01553 3.8e-29 yjaB_1 K Acetyltransferase (GNAT) domain
COKDBBLI_01554 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
COKDBBLI_01555 5.1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
COKDBBLI_01556 1.1e-17
COKDBBLI_01557 8.5e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
COKDBBLI_01558 4.1e-62 yneR
COKDBBLI_01559 5.6e-158 akr5f 1.1.1.346 S reductase
COKDBBLI_01560 1.3e-151 K Transcriptional regulator
COKDBBLI_01561 2.6e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
COKDBBLI_01562 1.4e-165 ypuA S Protein of unknown function (DUF1002)
COKDBBLI_01563 1.1e-87 padR K Virulence activator alpha C-term
COKDBBLI_01564 1.5e-92 padC Q Phenolic acid decarboxylase
COKDBBLI_01565 2.2e-38 C Flavodoxin
COKDBBLI_01566 5.6e-115 S Oxidoreductase, aldo keto reductase family protein
COKDBBLI_01567 4.2e-53 yphJ 4.1.1.44 S decarboxylase
COKDBBLI_01568 2.4e-10 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
COKDBBLI_01569 1.8e-115 P nitric oxide dioxygenase activity
COKDBBLI_01570 1.8e-108 S Peptidase propeptide and YPEB domain
COKDBBLI_01571 1.4e-240 T GHKL domain
COKDBBLI_01572 1e-122 T Transcriptional regulatory protein, C terminal
COKDBBLI_01573 7.2e-44 mleP3 S Membrane transport protein
COKDBBLI_01575 2.8e-07
COKDBBLI_01578 4.2e-130 2.7.13.3 T GHKL domain
COKDBBLI_01579 8.6e-118 K LytTr DNA-binding domain
COKDBBLI_01580 4.4e-289 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
COKDBBLI_01581 8.9e-24
COKDBBLI_01582 7.6e-20 relB L Addiction module antitoxin, RelB DinJ family
COKDBBLI_01583 1.8e-89 XK27_08850 J Aminoacyl-tRNA editing domain
COKDBBLI_01584 2.4e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COKDBBLI_01585 9.2e-192 V Beta-lactamase
COKDBBLI_01586 8.1e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COKDBBLI_01587 8e-120 yhiD S MgtC family
COKDBBLI_01588 5.6e-68 S GyrI-like small molecule binding domain
COKDBBLI_01589 2.5e-29 S GyrI-like small molecule binding domain
COKDBBLI_01591 2.8e-114 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
COKDBBLI_01592 1.2e-111 azlC E azaleucine resistance protein AzlC
COKDBBLI_01594 9.3e-78 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
COKDBBLI_01595 0.0 S SEC-C Motif Domain Protein
COKDBBLI_01596 1.8e-50
COKDBBLI_01597 1.1e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
COKDBBLI_01599 3.9e-09 E Collagen triple helix repeat (20 copies)
COKDBBLI_01601 4.5e-93 M Glycosyl hydrolases family 25
COKDBBLI_01602 1.5e-42 S Bacteriophage holin of superfamily 6 (Holin_LLH)
COKDBBLI_01603 9.7e-55 S Bacteriophage holin family
COKDBBLI_01604 7.1e-65 S Domain of unknown function (DUF2479)
COKDBBLI_01607 1.3e-185 S Peptidase family M23
COKDBBLI_01608 1.7e-96 S Phage tail protein
COKDBBLI_01609 0.0 D NLP P60 protein
COKDBBLI_01610 2.6e-92 S Phage tail assembly chaperone protein, TAC
COKDBBLI_01611 3.4e-120
COKDBBLI_01612 2.1e-70
COKDBBLI_01613 7.7e-84
COKDBBLI_01614 2.8e-51
COKDBBLI_01615 6.4e-63 S Phage gp6-like head-tail connector protein
COKDBBLI_01616 2.8e-199 gpG
COKDBBLI_01617 3.6e-75 S Domain of unknown function (DUF4355)
COKDBBLI_01618 1.4e-124 mltD CBM50 M NlpC P60 family protein
COKDBBLI_01619 5.7e-29
COKDBBLI_01620 3.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
COKDBBLI_01621 9.8e-32 ykzG S Belongs to the UPF0356 family
COKDBBLI_01622 1.3e-79
COKDBBLI_01623 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COKDBBLI_01624 6.8e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
COKDBBLI_01625 1.8e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
COKDBBLI_01626 1.8e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COKDBBLI_01627 1.6e-274 lpdA 1.8.1.4 C Dehydrogenase
COKDBBLI_01628 1.4e-47 yktA S Belongs to the UPF0223 family
COKDBBLI_01629 2.4e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
COKDBBLI_01630 0.0 typA T GTP-binding protein TypA
COKDBBLI_01631 7e-223 ftsW D Belongs to the SEDS family
COKDBBLI_01632 9.7e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
COKDBBLI_01633 1.2e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
COKDBBLI_01634 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COKDBBLI_01635 3.5e-199 ylbL T Belongs to the peptidase S16 family
COKDBBLI_01636 5.8e-80 comEA L Competence protein ComEA
COKDBBLI_01637 9e-89 comEB 3.5.4.12 F ComE operon protein 2
COKDBBLI_01638 0.0 comEC S Competence protein ComEC
COKDBBLI_01639 2.2e-145 holA 2.7.7.7 L DNA polymerase III delta subunit
COKDBBLI_01640 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
COKDBBLI_01641 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COKDBBLI_01642 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COKDBBLI_01643 7.1e-259 EGP Major facilitator Superfamily
COKDBBLI_01644 4.3e-85 perR P Belongs to the Fur family
COKDBBLI_01645 6.9e-232 cycA E Amino acid permease
COKDBBLI_01646 8.2e-102 V VanZ like family
COKDBBLI_01647 1e-23
COKDBBLI_01648 2.9e-85 S Short repeat of unknown function (DUF308)
COKDBBLI_01649 3.2e-77 S Psort location Cytoplasmic, score
COKDBBLI_01650 3.1e-281 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
COKDBBLI_01651 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
COKDBBLI_01652 4e-153 yeaE S Aldo keto
COKDBBLI_01653 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
COKDBBLI_01654 2.4e-167 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
COKDBBLI_01655 4.9e-150 xth 3.1.11.2 L exodeoxyribonuclease III
COKDBBLI_01656 2.2e-93 lytE M LysM domain protein
COKDBBLI_01657 0.0 oppD EP Psort location Cytoplasmic, score
COKDBBLI_01658 2.3e-81 lytE M LysM domain protein
COKDBBLI_01659 3.4e-150 sufD O Uncharacterized protein family (UPF0051)
COKDBBLI_01660 2.2e-110 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COKDBBLI_01661 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
COKDBBLI_01662 5.7e-196 lmrB EGP Major facilitator Superfamily
COKDBBLI_01663 7.1e-218 L Transposase
COKDBBLI_01664 3.5e-132 thrE S Putative threonine/serine exporter
COKDBBLI_01665 1.2e-82 S Threonine/Serine exporter, ThrE
COKDBBLI_01666 5.2e-119 lssY 3.6.1.27 I phosphatase
COKDBBLI_01667 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
COKDBBLI_01668 3.3e-275 lysP E amino acid
COKDBBLI_01669 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
COKDBBLI_01675 3.4e-180 S Hydrolases of the alpha beta superfamily
COKDBBLI_01676 4.7e-196 adhP 1.1.1.1 C alcohol dehydrogenase
COKDBBLI_01677 4.4e-77 ctsR K Belongs to the CtsR family
COKDBBLI_01678 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COKDBBLI_01679 3e-110 K Bacterial regulatory proteins, tetR family
COKDBBLI_01680 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COKDBBLI_01681 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COKDBBLI_01682 1.1e-39 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
COKDBBLI_01683 1.9e-158 rssA S Phospholipase, patatin family
COKDBBLI_01684 3.2e-118 L Integrase
COKDBBLI_01685 3e-151 EG EamA-like transporter family
COKDBBLI_01686 2.5e-129 narI 1.7.5.1 C Nitrate reductase
COKDBBLI_01687 3.7e-97 narJ C nitrate reductase molybdenum cofactor assembly chaperone
COKDBBLI_01688 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
COKDBBLI_01689 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COKDBBLI_01690 1e-187 moeB 2.7.7.73, 2.7.7.80 H ThiF family
COKDBBLI_01691 1.1e-78 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
COKDBBLI_01692 3.2e-228 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
COKDBBLI_01693 9.7e-83 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
COKDBBLI_01694 1.2e-103 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
COKDBBLI_01695 8.8e-44
COKDBBLI_01696 7.4e-189 comP 2.7.13.3 F Sensor histidine kinase
COKDBBLI_01697 2.3e-116 nreC K PFAM regulatory protein LuxR
COKDBBLI_01698 1.6e-18
COKDBBLI_01699 3.4e-180
COKDBBLI_01700 4.2e-164 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
COKDBBLI_01701 7.8e-219 narK P Transporter, major facilitator family protein
COKDBBLI_01702 1.7e-35 moaD 2.8.1.12 H ThiS family
COKDBBLI_01703 2.2e-64 moaE 2.8.1.12 H MoaE protein
COKDBBLI_01704 6.6e-78 S Flavodoxin
COKDBBLI_01708 1.4e-232 U TraM recognition site of TraD and TraG
COKDBBLI_01709 2e-68
COKDBBLI_01711 2.2e-29
COKDBBLI_01712 2.2e-194 U type IV secretory pathway VirB4
COKDBBLI_01714 1.3e-43 M Prophage endopeptidase tail
COKDBBLI_01717 8.3e-08 V CAAX protease self-immunity
COKDBBLI_01718 3.2e-29
COKDBBLI_01720 0.0 M NlpC/P60 family
COKDBBLI_01721 0.0 S Peptidase, M23
COKDBBLI_01722 9.3e-65 gntR1 K Transcriptional regulator, GntR family
COKDBBLI_01723 6.2e-157 V ABC transporter, ATP-binding protein
COKDBBLI_01724 2.5e-113
COKDBBLI_01725 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
COKDBBLI_01726 1.6e-98 S Pfam:DUF3816
COKDBBLI_01727 0.0 clpE O Belongs to the ClpA ClpB family
COKDBBLI_01728 6.4e-27
COKDBBLI_01729 2.7e-39 ptsH G phosphocarrier protein HPR
COKDBBLI_01730 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COKDBBLI_01731 7.9e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
COKDBBLI_01732 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
COKDBBLI_01733 1.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COKDBBLI_01734 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
COKDBBLI_01735 2.3e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
COKDBBLI_01736 4.2e-281 S C4-dicarboxylate anaerobic carrier
COKDBBLI_01737 5.9e-250 nhaC C Na H antiporter NhaC
COKDBBLI_01738 9.5e-242 pbuX F xanthine permease
COKDBBLI_01739 9.2e-283 pipD E Dipeptidase
COKDBBLI_01740 9.7e-169 corA P CorA-like Mg2+ transporter protein
COKDBBLI_01741 3.6e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COKDBBLI_01742 1.5e-130 terC P membrane
COKDBBLI_01743 6.1e-54 trxA O Belongs to the thioredoxin family
COKDBBLI_01744 8.4e-54 K Transcriptional regulator, ArsR family
COKDBBLI_01745 1.1e-93 P Cadmium resistance transporter
COKDBBLI_01746 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
COKDBBLI_01747 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
COKDBBLI_01748 1.8e-181 ABC-SBP S ABC transporter
COKDBBLI_01749 2.7e-74 M PFAM NLP P60 protein
COKDBBLI_01750 1.2e-07
COKDBBLI_01751 6.5e-100 S Protein of unknown function (DUF3278)
COKDBBLI_01752 2e-30 WQ51_00220 K Helix-turn-helix domain
COKDBBLI_01753 8.6e-80 yphH S Cupin domain
COKDBBLI_01754 4.5e-74 yeaL S UPF0756 membrane protein
COKDBBLI_01755 9.9e-242 EGP Major facilitator Superfamily
COKDBBLI_01756 1.1e-74 copY K Copper transport repressor CopY TcrY
COKDBBLI_01757 1.9e-245 yhdP S Transporter associated domain
COKDBBLI_01758 0.0 ubiB S ABC1 family
COKDBBLI_01759 2.8e-135 S DUF218 domain
COKDBBLI_01760 1.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COKDBBLI_01761 1e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COKDBBLI_01762 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COKDBBLI_01763 0.0 uvrA3 L excinuclease ABC, A subunit
COKDBBLI_01764 1e-122 S SNARE associated Golgi protein
COKDBBLI_01765 1.2e-230 N Uncharacterized conserved protein (DUF2075)
COKDBBLI_01766 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COKDBBLI_01768 3.9e-254 yifK E Amino acid permease
COKDBBLI_01769 2.9e-13 K Transcriptional regulator, HxlR family
COKDBBLI_01770 2.1e-216 P ammonium transporter
COKDBBLI_01771 4.4e-94 ureI S AmiS/UreI family transporter
COKDBBLI_01772 6.5e-45 ureA 3.5.1.5 E Urease, gamma subunit
COKDBBLI_01773 7.7e-64 ureB 3.5.1.5 E Urease beta subunit
COKDBBLI_01774 0.0 ureC 3.5.1.5 E Amidohydrolase family
COKDBBLI_01775 3.3e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
COKDBBLI_01776 6.2e-131 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
COKDBBLI_01777 2.1e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
COKDBBLI_01778 6.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
COKDBBLI_01779 5.5e-41 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COKDBBLI_01780 4.5e-73 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COKDBBLI_01781 1.4e-184 nikMN P PDGLE domain
COKDBBLI_01782 7.9e-133 P Cobalt transport protein
COKDBBLI_01783 1.1e-135 cbiO P ABC transporter
COKDBBLI_01784 3e-133 K Transcriptional regulatory protein, C-terminal domain protein
COKDBBLI_01785 1.2e-155 pstS P Phosphate
COKDBBLI_01786 4.7e-152 pstC P probably responsible for the translocation of the substrate across the membrane
COKDBBLI_01787 1.4e-153 pstA P Phosphate transport system permease protein PstA
COKDBBLI_01788 2.3e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COKDBBLI_01789 2.1e-123 phoU P Plays a role in the regulation of phosphate uptake
COKDBBLI_01790 1.2e-135 pnuC H nicotinamide mononucleotide transporter
COKDBBLI_01791 3.7e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COKDBBLI_01792 1.1e-201
COKDBBLI_01793 7.7e-52
COKDBBLI_01794 9.1e-36
COKDBBLI_01795 8.2e-93 yxkA S Phosphatidylethanolamine-binding protein
COKDBBLI_01796 3.2e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
COKDBBLI_01797 1.9e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
COKDBBLI_01798 2.9e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COKDBBLI_01799 9e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
COKDBBLI_01800 3.8e-179 galR K Transcriptional regulator
COKDBBLI_01801 3.6e-95 dedA 3.1.3.1 S SNARE associated Golgi protein
COKDBBLI_01802 5.2e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COKDBBLI_01803 1.3e-79 K AsnC family
COKDBBLI_01804 1.5e-80 uspA T universal stress protein
COKDBBLI_01805 0.0 lacS G Transporter
COKDBBLI_01806 3.9e-38
COKDBBLI_01807 2.1e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COKDBBLI_01808 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COKDBBLI_01809 4.1e-190 yeaN P Transporter, major facilitator family protein
COKDBBLI_01810 4.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
COKDBBLI_01811 1.3e-84 nrdI F Belongs to the NrdI family
COKDBBLI_01812 2.1e-241 yhdP S Transporter associated domain
COKDBBLI_01813 1.4e-153 ypdB V (ABC) transporter
COKDBBLI_01814 6.7e-90 GM epimerase
COKDBBLI_01815 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
COKDBBLI_01816 8.7e-78 yybA 2.3.1.57 K Transcriptional regulator
COKDBBLI_01817 8.9e-133 XK27_07210 6.1.1.6 S B3 4 domain
COKDBBLI_01818 4.3e-163 S AI-2E family transporter
COKDBBLI_01819 1e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
COKDBBLI_01820 5.7e-137
COKDBBLI_01821 2.1e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COKDBBLI_01822 6.4e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COKDBBLI_01823 4.1e-309 lmrA V ABC transporter, ATP-binding protein
COKDBBLI_01824 0.0 yfiC V ABC transporter
COKDBBLI_01825 1.4e-283 pipD E Dipeptidase
COKDBBLI_01826 2.7e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COKDBBLI_01827 1.5e-132 gntR K UbiC transcription regulator-associated domain protein
COKDBBLI_01828 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
COKDBBLI_01829 1.1e-242 yagE E amino acid
COKDBBLI_01830 5.9e-140 aroD S Serine hydrolase (FSH1)
COKDBBLI_01831 2.4e-240 brnQ U Component of the transport system for branched-chain amino acids
COKDBBLI_01832 2e-166 GK ROK family
COKDBBLI_01833 0.0 tetP J elongation factor G
COKDBBLI_01834 1.9e-80 uspA T universal stress protein
COKDBBLI_01835 3.3e-194 lplA 6.3.1.20 H Lipoate-protein ligase
COKDBBLI_01836 7.1e-63
COKDBBLI_01837 5.2e-14
COKDBBLI_01838 5.5e-111
COKDBBLI_01839 8.8e-135 V ABC transporter
COKDBBLI_01840 2.4e-212 EGP Major facilitator Superfamily
COKDBBLI_01841 4.2e-256 G PTS system Galactitol-specific IIC component
COKDBBLI_01842 9.9e-39 1.6.5.5 C Zinc-binding dehydrogenase
COKDBBLI_01843 4.8e-64 1.6.5.5 C Zinc-binding dehydrogenase
COKDBBLI_01844 1.8e-34 1.6.5.5 C Zinc-binding dehydrogenase
COKDBBLI_01845 7e-161
COKDBBLI_01846 1e-72 K Transcriptional regulator
COKDBBLI_01847 1.5e-188 D Alpha beta
COKDBBLI_01848 3.8e-52 ypaA S Protein of unknown function (DUF1304)
COKDBBLI_01849 0.0 yjcE P Sodium proton antiporter
COKDBBLI_01850 1.6e-52 yvlA
COKDBBLI_01851 7.5e-115 P Cobalt transport protein
COKDBBLI_01852 7.6e-250 cbiO1 S ABC transporter, ATP-binding protein
COKDBBLI_01853 1.2e-97 S ABC-type cobalt transport system, permease component
COKDBBLI_01854 3.3e-133 S membrane transporter protein
COKDBBLI_01855 1.2e-137 IQ KR domain
COKDBBLI_01856 2.8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
COKDBBLI_01857 1.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
COKDBBLI_01858 5.7e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
COKDBBLI_01859 1.7e-249 yagE E amino acid
COKDBBLI_01860 7.6e-85 dps P Belongs to the Dps family
COKDBBLI_01861 0.0 pacL 3.6.3.8 P P-type ATPase
COKDBBLI_01862 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
COKDBBLI_01863 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COKDBBLI_01864 2.2e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COKDBBLI_01865 4.5e-146 potB P ABC transporter permease
COKDBBLI_01866 5.5e-131 potC P ABC transporter permease
COKDBBLI_01867 8.6e-209 potD P ABC transporter
COKDBBLI_01868 4.3e-231
COKDBBLI_01869 5e-235 EGP Sugar (and other) transporter
COKDBBLI_01870 7.9e-255 yfnA E Amino Acid
COKDBBLI_01871 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
COKDBBLI_01872 6.4e-102 gmk2 2.7.4.8 F Guanylate kinase
COKDBBLI_01873 1.5e-82 zur P Belongs to the Fur family
COKDBBLI_01874 1.2e-16 3.2.1.14 GH18
COKDBBLI_01875 5.4e-150
COKDBBLI_01876 1.4e-37 pspC KT PspC domain protein
COKDBBLI_01877 1.6e-94 K Transcriptional regulator (TetR family)
COKDBBLI_01878 3.4e-220 V domain protein
COKDBBLI_01879 1.2e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COKDBBLI_01881 6.6e-35 S Transglycosylase associated protein
COKDBBLI_01882 3.5e-233 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COKDBBLI_01883 1.9e-126 G phosphoglycerate mutase
COKDBBLI_01884 4.8e-114 dedA S SNARE associated Golgi protein
COKDBBLI_01885 0.0 helD 3.6.4.12 L DNA helicase
COKDBBLI_01886 4.6e-244 nox C NADH oxidase
COKDBBLI_01887 7.2e-253 nox C NADH oxidase
COKDBBLI_01888 5.6e-158 EG EamA-like transporter family
COKDBBLI_01889 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COKDBBLI_01890 8.2e-176 coaA 2.7.1.33 F Pantothenic acid kinase
COKDBBLI_01891 4.3e-225 S cog cog1373
COKDBBLI_01893 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COKDBBLI_01894 3.3e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COKDBBLI_01895 7e-143 topA2 5.99.1.2 G Topoisomerase IA
COKDBBLI_01896 2.1e-51 L Protein of unknown function (DUF3991)
COKDBBLI_01897 1e-08 nrdH O Glutaredoxin
COKDBBLI_01900 2.5e-14 K ORF6N domain
COKDBBLI_01901 7.2e-33 XK27_00515 D Glucan-binding protein C
COKDBBLI_01903 1.4e-11 ftsZ D Cell surface antigen C-terminus
COKDBBLI_01904 4.1e-56 L Belongs to the 'phage' integrase family
COKDBBLI_01906 1.3e-193 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
COKDBBLI_01907 1.5e-227 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
COKDBBLI_01908 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COKDBBLI_01909 1.2e-155 asp3 S Accessory Sec secretory system ASP3
COKDBBLI_01910 5e-215 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
COKDBBLI_01911 1.4e-196 M transferase activity, transferring glycosyl groups
COKDBBLI_01912 3e-162 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
COKDBBLI_01913 3.5e-111 nss M transferase activity, transferring glycosyl groups
COKDBBLI_01914 1.3e-54 M family 8
COKDBBLI_01916 5.5e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COKDBBLI_01917 1.3e-61 psiE S Phosphate-starvation-inducible E
COKDBBLI_01918 1.3e-101 ydeN S Serine hydrolase
COKDBBLI_01920 5.4e-184 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COKDBBLI_01921 4.5e-258 nhaC C Na H antiporter NhaC
COKDBBLI_01922 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
COKDBBLI_01923 3.1e-113 ywnB S NAD(P)H-binding
COKDBBLI_01924 9.8e-38
COKDBBLI_01925 1.9e-130 IQ Dehydrogenase reductase
COKDBBLI_01926 6.1e-241 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
COKDBBLI_01927 2.3e-08
COKDBBLI_01929 5.9e-208 L Transposase
COKDBBLI_01932 3e-100 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COKDBBLI_01933 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
COKDBBLI_01934 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COKDBBLI_01935 6.9e-229 cinA 3.5.1.42 S Belongs to the CinA family
COKDBBLI_01936 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COKDBBLI_01937 2.6e-138 ymfM S Helix-turn-helix domain
COKDBBLI_01938 1.8e-248 ymfH S Peptidase M16
COKDBBLI_01939 1.9e-228 ymfF S Peptidase M16 inactive domain protein
COKDBBLI_01940 2.6e-160 aatB ET ABC transporter substrate-binding protein
COKDBBLI_01941 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COKDBBLI_01942 3.2e-102 glnP P ABC transporter permease
COKDBBLI_01943 8.7e-93 mreD M rod shape-determining protein MreD
COKDBBLI_01944 7.7e-152 mreC M Involved in formation and maintenance of cell shape
COKDBBLI_01945 1.7e-179 mreB D cell shape determining protein MreB
COKDBBLI_01946 3.4e-120 radC L DNA repair protein
COKDBBLI_01947 3.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
COKDBBLI_01948 7.5e-58 ytzB S Small secreted protein
COKDBBLI_01949 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
COKDBBLI_01950 1.6e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COKDBBLI_01951 2.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
COKDBBLI_01952 2.1e-118 ybhL S Belongs to the BI1 family
COKDBBLI_01953 1e-119 yoaK S Protein of unknown function (DUF1275)
COKDBBLI_01954 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COKDBBLI_01955 2.6e-152 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COKDBBLI_01956 4.5e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COKDBBLI_01957 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COKDBBLI_01958 3.4e-226 dnaB L replication initiation and membrane attachment
COKDBBLI_01959 9.6e-172 dnaI L Primosomal protein DnaI
COKDBBLI_01960 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COKDBBLI_01961 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
COKDBBLI_01962 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COKDBBLI_01963 4.2e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COKDBBLI_01965 0.0 infB UW LPXTG-motif cell wall anchor domain protein
COKDBBLI_01966 0.0 trxB2 1.8.1.9 C Thioredoxin domain
COKDBBLI_01967 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
COKDBBLI_01968 5.5e-137 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COKDBBLI_01969 8.7e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
COKDBBLI_01971 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COKDBBLI_01972 7.1e-166 T Calcineurin-like phosphoesterase superfamily domain
COKDBBLI_01973 2.4e-223 mdtG EGP Major facilitator Superfamily
COKDBBLI_01974 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
COKDBBLI_01975 4.7e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
COKDBBLI_01976 1.1e-143 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
COKDBBLI_01977 2.6e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
COKDBBLI_01978 4.3e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COKDBBLI_01979 9.1e-74 K SIR2-like domain
COKDBBLI_01980 9.5e-178 hsdM 2.1.1.72 V type I restriction-modification system
COKDBBLI_01981 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
COKDBBLI_01982 7.7e-26 K Cro/C1-type HTH DNA-binding domain
COKDBBLI_01983 1.6e-82 L AAA domain
COKDBBLI_01984 8.9e-14
COKDBBLI_01985 3.3e-32
COKDBBLI_01987 2.2e-25
COKDBBLI_01988 1.5e-19
COKDBBLI_01989 3.2e-17 S Domain of Unknown Function with PDB structure (DUF3850)
COKDBBLI_01991 2.9e-12
COKDBBLI_02006 9.8e-29 L Psort location Cytoplasmic, score
COKDBBLI_02009 6.5e-08 S Arc-like DNA binding domain
COKDBBLI_02012 1.9e-29 S COG0463 Glycosyltransferases involved in cell wall biogenesis
COKDBBLI_02013 1.9e-29 M PFAM Glycosyl transferase family 2
COKDBBLI_02014 2.1e-28 M Glycosyltransferase sugar-binding region containing DXD motif
COKDBBLI_02015 7.5e-73 cps2I S Psort location CytoplasmicMembrane, score
COKDBBLI_02017 6e-41 GT2,GT4 M Glycosyltransferase GT-D fold
COKDBBLI_02018 1.2e-66 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
COKDBBLI_02019 4.1e-87 GT4 G Glycosyl transferase 4-like
COKDBBLI_02020 2.2e-47 pglC M Bacterial sugar transferase
COKDBBLI_02021 2.7e-108 ywqD 2.7.10.1 D Capsular exopolysaccharide family
COKDBBLI_02022 2.3e-99 epsB M biosynthesis protein
COKDBBLI_02023 1e-281 O Arylsulfotransferase (ASST)
COKDBBLI_02024 9.1e-298 L Transposase
COKDBBLI_02025 3.1e-206 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
COKDBBLI_02026 2.3e-218 G Transporter, major facilitator family protein
COKDBBLI_02027 3.8e-246 E Peptidase family M20/M25/M40
COKDBBLI_02028 1.3e-25 K Transcriptional regulator, LysR family
COKDBBLI_02029 1e-99 K Transcriptional regulator, LysR family
COKDBBLI_02030 2.3e-55 znuA P Belongs to the bacterial solute-binding protein 9 family
COKDBBLI_02031 1.4e-64 XK27_06920 S Protein of unknown function (DUF1700)
COKDBBLI_02032 2e-48 L PFAM transposase IS200-family protein
COKDBBLI_02033 6.8e-52 entB 3.5.1.19 Q Isochorismatase family
COKDBBLI_02034 1.7e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COKDBBLI_02035 1.2e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COKDBBLI_02036 5.2e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COKDBBLI_02037 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COKDBBLI_02038 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COKDBBLI_02039 1.3e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COKDBBLI_02040 9.8e-67 yabR J RNA binding
COKDBBLI_02041 1.1e-56 divIC D Septum formation initiator
COKDBBLI_02042 2.1e-39 yabO J S4 domain protein
COKDBBLI_02043 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COKDBBLI_02044 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COKDBBLI_02045 2.4e-113 S (CBS) domain
COKDBBLI_02046 3.1e-147 tesE Q hydratase
COKDBBLI_02047 3.4e-241 codA 3.5.4.1 F cytosine deaminase
COKDBBLI_02048 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
COKDBBLI_02049 2.7e-61 L Toxic component of a toxin-antitoxin (TA) module
COKDBBLI_02050 1.6e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COKDBBLI_02051 2.6e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COKDBBLI_02053 1.2e-291 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COKDBBLI_02054 1.1e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
COKDBBLI_02055 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COKDBBLI_02056 6.2e-254 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COKDBBLI_02057 7.7e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
COKDBBLI_02058 0.0 sprD D Domain of Unknown Function (DUF1542)
COKDBBLI_02059 5.3e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COKDBBLI_02060 5.2e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COKDBBLI_02061 9.8e-158 htpX O Belongs to the peptidase M48B family
COKDBBLI_02062 7e-93 lemA S LemA family
COKDBBLI_02063 2.3e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COKDBBLI_02064 1.3e-119 pgm3 G Belongs to the phosphoglycerate mutase family
COKDBBLI_02065 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
COKDBBLI_02066 1.3e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COKDBBLI_02067 2.7e-159 3.2.1.55 GH51 G Right handed beta helix region
COKDBBLI_02068 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
COKDBBLI_02069 9.5e-124 srtA 3.4.22.70 M sortase family
COKDBBLI_02070 2e-166 S Alpha/beta hydrolase of unknown function (DUF915)
COKDBBLI_02071 1.7e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COKDBBLI_02072 4.6e-41 rpmE2 J Ribosomal protein L31
COKDBBLI_02073 1.2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COKDBBLI_02074 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COKDBBLI_02075 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COKDBBLI_02076 3e-66 ywiB S Domain of unknown function (DUF1934)
COKDBBLI_02077 1.8e-145 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
COKDBBLI_02078 1.7e-270 ywfO S HD domain protein
COKDBBLI_02079 8.4e-148 yxeH S hydrolase
COKDBBLI_02080 2.1e-49
COKDBBLI_02081 3.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COKDBBLI_02082 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COKDBBLI_02083 2.6e-149 purR 2.4.2.7 F pur operon repressor
COKDBBLI_02084 4.7e-119 znuB U ABC 3 transport family
COKDBBLI_02085 2.2e-122 fhuC P ABC transporter
COKDBBLI_02086 2.5e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
COKDBBLI_02087 2.6e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COKDBBLI_02088 6.8e-37 veg S Biofilm formation stimulator VEG
COKDBBLI_02089 1e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COKDBBLI_02090 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COKDBBLI_02091 1.1e-155 tatD L hydrolase, TatD family
COKDBBLI_02092 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COKDBBLI_02093 6.2e-162 yunF F Protein of unknown function DUF72
COKDBBLI_02095 2.2e-128 cobB K SIR2 family
COKDBBLI_02096 1.8e-178
COKDBBLI_02097 6.3e-227 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
COKDBBLI_02098 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COKDBBLI_02099 2.2e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
COKDBBLI_02100 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
COKDBBLI_02101 8.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
COKDBBLI_02102 0.0 helD 3.6.4.12 L DNA helicase
COKDBBLI_02103 1.6e-200 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COKDBBLI_02104 1.4e-195 clcA P chloride
COKDBBLI_02105 1.7e-84 L PFAM transposase IS200-family protein
COKDBBLI_02107 2.1e-56 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
COKDBBLI_02108 2.5e-31
COKDBBLI_02111 3.7e-14 K Cro/C1-type HTH DNA-binding domain
COKDBBLI_02112 2.8e-46 ebh D nuclear chromosome segregation
COKDBBLI_02114 1e-10 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
COKDBBLI_02115 1.4e-09 L Resolvase, N terminal domain
COKDBBLI_02116 5.4e-77 L Resolvase, N terminal domain
COKDBBLI_02117 2.4e-104 yocS S SBF-like CPA transporter family (DUF4137)
COKDBBLI_02118 4.8e-130 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
COKDBBLI_02119 2.5e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
COKDBBLI_02120 1.2e-230 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
COKDBBLI_02121 1.5e-206 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
COKDBBLI_02122 1.1e-204 ydiN G Major Facilitator Superfamily
COKDBBLI_02123 1.9e-155 menH 2.2.1.9, 4.2.99.20, 6.2.1.26 I Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
COKDBBLI_02124 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
COKDBBLI_02125 1.1e-250 menF 5.4.4.2 HQ chorismate binding enzyme
COKDBBLI_02126 4e-54 S Uncharacterised protein family (UPF0236)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)