ORF_ID e_value Gene_name EC_number CAZy COGs Description
GPNIHGFM_00001 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M COG0744 Membrane carboxypeptidase (penicillin-binding protein)
GPNIHGFM_00002 5.4e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPNIHGFM_00003 3.9e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPNIHGFM_00004 2.7e-85 ytsP 1.8.4.14 T GAF domain-containing protein
GPNIHGFM_00005 3.1e-113 yttP K Transcriptional regulator
GPNIHGFM_00006 5.5e-141 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
GPNIHGFM_00007 1.6e-297 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GPNIHGFM_00008 8e-205 iscS2 2.8.1.7 E Cysteine desulfurase
GPNIHGFM_00009 5.8e-222 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPNIHGFM_00010 8.1e-28 sspB S spore protein
GPNIHGFM_00011 5.5e-178 sppA OU signal peptide peptidase SppA
GPNIHGFM_00012 1.3e-96 yteJ S RDD family
GPNIHGFM_00013 1.8e-119 ytfI S Protein of unknown function (DUF2953)
GPNIHGFM_00014 8.4e-75 ytfJ S Sporulation protein YtfJ
GPNIHGFM_00015 3.1e-191 ywoG EGP Major facilitator Superfamily
GPNIHGFM_00016 1.8e-84 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GPNIHGFM_00017 1.7e-179 ytxK 2.1.1.72 L DNA methylase
GPNIHGFM_00018 5.6e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPNIHGFM_00019 2.1e-166 yhaM S 3'-5' exoribonuclease yhaM
GPNIHGFM_00020 2.1e-10 S EcsC protein family
GPNIHGFM_00021 1.4e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GPNIHGFM_00022 7.1e-256 argH 4.3.2.1 E argininosuccinate lyase
GPNIHGFM_00024 4.7e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_00025 1e-63
GPNIHGFM_00026 4.4e-200 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
GPNIHGFM_00027 1.3e-125 ytkL S Belongs to the UPF0173 family
GPNIHGFM_00029 6.7e-240 ytoI K transcriptional regulator containing CBS domains
GPNIHGFM_00030 4.6e-08 ytpI S YtpI-like protein
GPNIHGFM_00031 4.6e-166 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
GPNIHGFM_00032 4.2e-89 ytrI
GPNIHGFM_00033 7.2e-53 ytrH S Sporulation protein YtrH
GPNIHGFM_00034 0.0 dnaE 2.7.7.7 L DNA polymerase
GPNIHGFM_00035 3.4e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
GPNIHGFM_00036 5.8e-115 lutR_1 K helix_turn_helix gluconate operon transcriptional repressor
GPNIHGFM_00037 6.8e-153 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPNIHGFM_00038 7.6e-180 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GPNIHGFM_00039 2.2e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GPNIHGFM_00040 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GPNIHGFM_00041 9.3e-60 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
GPNIHGFM_00042 6.7e-73 yeaL S UPF0756 membrane protein
GPNIHGFM_00043 2.1e-205 citZ 2.3.3.1 C Belongs to the citrate synthase family
GPNIHGFM_00044 4.5e-241 icd 1.1.1.42 C isocitrate
GPNIHGFM_00045 2.6e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
GPNIHGFM_00046 2.2e-73 lrpC K helix_turn_helix ASNC type
GPNIHGFM_00047 1.5e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNIHGFM_00048 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
GPNIHGFM_00049 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPNIHGFM_00050 1e-153 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GPNIHGFM_00051 1.3e-103 ytaF P Probably functions as a manganese efflux pump
GPNIHGFM_00052 2.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPNIHGFM_00053 3.2e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPNIHGFM_00054 5.4e-68 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GPNIHGFM_00055 3.3e-65
GPNIHGFM_00056 5.1e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPNIHGFM_00057 3.9e-241 dnaB L Membrane attachment protein
GPNIHGFM_00058 3.6e-171 dnaI L Primosomal protein DnaI
GPNIHGFM_00059 8.7e-223 mqnC 1.21.98.1, 2.5.1.120, 2.5.1.77 H Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)
GPNIHGFM_00060 9e-161 ytxC S YtxC-like family
GPNIHGFM_00061 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPNIHGFM_00062 1.7e-182 S Oxidoreductase family, NAD-binding Rossmann fold
GPNIHGFM_00063 1.1e-175 strT C Aldo/keto reductase family
GPNIHGFM_00064 9.8e-264 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
GPNIHGFM_00065 2.5e-122
GPNIHGFM_00066 5.3e-232 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPNIHGFM_00067 1.2e-118 macB V ABC transporter, ATP-binding protein
GPNIHGFM_00068 2e-206 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
GPNIHGFM_00069 2.1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPNIHGFM_00070 1.7e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GPNIHGFM_00071 2.3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPNIHGFM_00072 7.9e-52 S Protein of unknown function, DUF485
GPNIHGFM_00073 1.8e-260 actP S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPNIHGFM_00074 1.7e-64 ysdB S Sigma-w pathway protein YsdB
GPNIHGFM_00075 5.9e-202 ysdC G COG1363 Cellulase M and related proteins
GPNIHGFM_00076 2.4e-17
GPNIHGFM_00078 6.3e-31 sspI S Belongs to the SspI family
GPNIHGFM_00079 2.5e-127 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPNIHGFM_00080 1.7e-193 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPNIHGFM_00081 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPNIHGFM_00082 1.3e-32 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPNIHGFM_00083 5.7e-84 cvpA S membrane protein, required for colicin V production
GPNIHGFM_00084 0.0 polX L COG1796 DNA polymerase IV (family X)
GPNIHGFM_00085 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPNIHGFM_00086 6.9e-66 yshE S membrane
GPNIHGFM_00087 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPNIHGFM_00088 3.2e-101 fadR K Transcriptional regulator
GPNIHGFM_00089 8.8e-131 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
GPNIHGFM_00090 5.5e-133 etfB C Electron transfer flavoprotein
GPNIHGFM_00091 1.5e-172 etfA C Electron transfer flavoprotein
GPNIHGFM_00092 1.8e-53 trxA O Belongs to the thioredoxin family
GPNIHGFM_00093 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GPNIHGFM_00094 1.3e-75 yslB S Protein of unknown function (DUF2507)
GPNIHGFM_00095 4.7e-228 ktrB P COG0168 Trk-type K transport systems, membrane components
GPNIHGFM_00096 2.7e-111 sdhC C succinate dehydrogenase
GPNIHGFM_00097 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
GPNIHGFM_00098 2.8e-145 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
GPNIHGFM_00099 1.9e-77 fcbC S thioesterase
GPNIHGFM_00100 1.6e-32 gerE K Transcriptional regulator
GPNIHGFM_00101 1.3e-38 ptsH G phosphocarrier protein HPr
GPNIHGFM_00102 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPNIHGFM_00103 1.2e-79 ysmB 2.4.2.28 K transcriptional
GPNIHGFM_00104 1.7e-148 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GPNIHGFM_00105 2.5e-23 C 4Fe-4S binding domain
GPNIHGFM_00106 9.2e-194 yceA S Belongs to the UPF0176 family
GPNIHGFM_00107 7.7e-176 gerM S COG5401 Spore germination protein
GPNIHGFM_00108 2e-135 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPNIHGFM_00109 2.4e-104 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPNIHGFM_00110 8.8e-95 ysnB S Phosphoesterase
GPNIHGFM_00113 4.1e-10
GPNIHGFM_00115 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
GPNIHGFM_00116 3.1e-238 hsdM 2.1.1.72 V Type I restriction-modification system
GPNIHGFM_00117 9.1e-118 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
GPNIHGFM_00118 3.7e-306 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
GPNIHGFM_00120 1.7e-263 M Glycosyl transferase family group 2
GPNIHGFM_00121 2.6e-68
GPNIHGFM_00122 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GPNIHGFM_00123 0.0 ilvB 2.2.1.6 E Acetolactate synthase
GPNIHGFM_00124 4.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
GPNIHGFM_00125 4.4e-178 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPNIHGFM_00126 1.4e-284 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPNIHGFM_00127 4.7e-194 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GPNIHGFM_00128 4.1e-267 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPNIHGFM_00129 9.2e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPNIHGFM_00130 1.2e-177 trxA2 O COG0457 FOG TPR repeat
GPNIHGFM_00131 3.7e-230 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GPNIHGFM_00132 1e-237 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPNIHGFM_00133 4e-306 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
GPNIHGFM_00134 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPNIHGFM_00135 2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
GPNIHGFM_00136 3.6e-244 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPNIHGFM_00137 1.6e-146 hemX O cytochrome C
GPNIHGFM_00138 3e-165 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GPNIHGFM_00139 2.1e-132 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
GPNIHGFM_00140 1.9e-178 hemB 4.2.1.24 H Belongs to the ALAD family
GPNIHGFM_00141 1.8e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
GPNIHGFM_00142 6.9e-156 spoVID M stage VI sporulation protein D
GPNIHGFM_00143 2.4e-156
GPNIHGFM_00144 1.9e-186 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPNIHGFM_00145 1.7e-102
GPNIHGFM_00146 1.1e-27
GPNIHGFM_00147 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GPNIHGFM_00148 2.8e-230 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GPNIHGFM_00149 6.1e-118 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
GPNIHGFM_00150 2.1e-194
GPNIHGFM_00151 0.0 yuxL 3.4.19.1 EU peptidase
GPNIHGFM_00152 4.2e-101 maf D septum formation protein Maf
GPNIHGFM_00153 2.8e-120 radC E Belongs to the UPF0758 family
GPNIHGFM_00154 1.5e-186 mreB D Rod shape-determining protein MreB
GPNIHGFM_00155 2.1e-160 mreC M Involved in formation and maintenance of cell shape
GPNIHGFM_00156 8.8e-74 mreD M shape-determining protein
GPNIHGFM_00157 6.6e-122 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GPNIHGFM_00158 1.6e-140 minD D Belongs to the ParA family
GPNIHGFM_00159 5.9e-92 yfkM 3.5.1.124 S protease
GPNIHGFM_00160 3.4e-74 moaC 4.6.1.17 H MoaC family
GPNIHGFM_00161 2.9e-91 bioY S BioY family
GPNIHGFM_00162 2.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
GPNIHGFM_00163 1.2e-126 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
GPNIHGFM_00164 1.8e-133 spoIVFB S Stage IV sporulation protein
GPNIHGFM_00165 1.8e-265 rng J ribonuclease, Rne Rng family
GPNIHGFM_00166 2.2e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
GPNIHGFM_00167 5.3e-56 ysxB J ribosomal protein
GPNIHGFM_00168 1.7e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GPNIHGFM_00169 4e-44 abrB K SpoVT / AbrB like domain
GPNIHGFM_00170 1.2e-213 Q COG1228 Imidazolonepropionase and related amidohydrolases
GPNIHGFM_00172 3.5e-117 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
GPNIHGFM_00173 3.8e-207 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
GPNIHGFM_00174 2.2e-128 S Peptidase C26
GPNIHGFM_00175 3.3e-267 nylA 3.5.1.4 J Belongs to the amidase family
GPNIHGFM_00176 1.3e-76 S DinB family
GPNIHGFM_00177 1e-165 pstS P Phosphate
GPNIHGFM_00178 6.4e-160 pstC P probably responsible for the translocation of the substrate across the membrane
GPNIHGFM_00179 9.4e-161 pstA P Phosphate transport system permease
GPNIHGFM_00180 7.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPNIHGFM_00181 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPNIHGFM_00182 6.1e-109 phoU P Plays a role in the regulation of phosphate uptake
GPNIHGFM_00183 7.8e-61
GPNIHGFM_00184 0.0 addB 3.6.4.12 L exonuclease activity
GPNIHGFM_00185 0.0 recB 3.1.11.5, 3.1.12.1, 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GPNIHGFM_00186 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
GPNIHGFM_00187 2.9e-67 cheW NT chemotaxis
GPNIHGFM_00188 0.0 asnB 6.3.5.4 E Asparagine synthase
GPNIHGFM_00189 4.7e-48 S IDEAL
GPNIHGFM_00190 1.5e-152 ykgA E Amidinotransferase
GPNIHGFM_00191 7.4e-283 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GPNIHGFM_00192 5.4e-90
GPNIHGFM_00193 1.1e-62 ytwF P Sulfurtransferase
GPNIHGFM_00194 3.3e-40
GPNIHGFM_00195 8.9e-147 yjfP S COG1073 Hydrolases of the alpha beta superfamily
GPNIHGFM_00196 1.8e-145 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
GPNIHGFM_00197 2.3e-31 ipi S Intracellular proteinase inhibitor
GPNIHGFM_00199 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
GPNIHGFM_00200 4.6e-214 ywqB S zinc ion binding
GPNIHGFM_00201 1.4e-107
GPNIHGFM_00202 1.8e-78 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) domain
GPNIHGFM_00203 3.4e-149 yitU 3.1.3.104 S hydrolases of the HAD superfamily
GPNIHGFM_00204 9.7e-166 ctaG S cytochrome c oxidase
GPNIHGFM_00205 4.4e-194 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPNIHGFM_00206 8.3e-224 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GPNIHGFM_00207 3.1e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
GPNIHGFM_00208 4.8e-213 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
GPNIHGFM_00209 1.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GPNIHGFM_00210 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
GPNIHGFM_00211 2.4e-170 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPNIHGFM_00212 1.1e-116 yjaU I carboxylic ester hydrolase activity
GPNIHGFM_00213 2.6e-144 5.1.3.2 GM RmlD substrate binding domain
GPNIHGFM_00214 6.6e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GPNIHGFM_00215 1.4e-13 comZ S ComZ
GPNIHGFM_00217 7.1e-167 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPNIHGFM_00218 7.8e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GPNIHGFM_00219 0.0 cca 2.7.7.19, 2.7.7.72, 3.1.13.3, 3.1.3.7 J Poly A polymerase head domain
GPNIHGFM_00221 2.3e-102 3.5.1.28 M Cell Wall Hydrolase
GPNIHGFM_00222 3.9e-107 J protein with SCP PR1 domains
GPNIHGFM_00223 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
GPNIHGFM_00224 3.4e-135 ywaC 2.7.6.5 S protein conserved in bacteria
GPNIHGFM_00225 1.7e-153 yjaZ O Zn-dependent protease
GPNIHGFM_00226 2.2e-139 yjbA S Belongs to the UPF0736 family
GPNIHGFM_00227 2.7e-10
GPNIHGFM_00228 2.2e-179 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
GPNIHGFM_00230 2.9e-102 stoA CO Redoxin
GPNIHGFM_00231 5.3e-98 yueE S phosphohydrolase
GPNIHGFM_00232 2.2e-111 yplQ S protein, Hemolysin III
GPNIHGFM_00233 3.4e-14 yoeD G Helix-turn-helix domain
GPNIHGFM_00234 1.3e-232 S Putative glycosyl hydrolase domain
GPNIHGFM_00235 7.7e-97 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNIHGFM_00237 1.3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GPNIHGFM_00238 6.1e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GPNIHGFM_00239 1.4e-204 yjbF S Competence protein
GPNIHGFM_00241 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
GPNIHGFM_00242 5.6e-73 yjbI S COG2346 Truncated hemoglobins
GPNIHGFM_00243 2e-94 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GPNIHGFM_00244 2.2e-94 yjbK S protein conserved in bacteria
GPNIHGFM_00245 2.7e-61 yjbL S Belongs to the UPF0738 family
GPNIHGFM_00246 2e-109 yjbM 2.7.6.5 S GTP pyrophosphokinase
GPNIHGFM_00247 2e-149 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPNIHGFM_00248 3e-162 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPNIHGFM_00249 8.3e-137 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
GPNIHGFM_00250 3.8e-57 yngL S Protein of unknown function (DUF1360)
GPNIHGFM_00251 1.6e-137 Q ubiE/COQ5 methyltransferase family
GPNIHGFM_00252 5.4e-119
GPNIHGFM_00253 1.1e-135
GPNIHGFM_00256 3.5e-60 cotX S Spore Coat Protein X and V domain
GPNIHGFM_00257 2.1e-52
GPNIHGFM_00258 0.0 yjcD 3.6.4.12 L DNA helicase
GPNIHGFM_00259 1.1e-176 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPNIHGFM_00260 8.6e-182 comGB NU COG1459 Type II secretory pathway, component PulF
GPNIHGFM_00262 8.7e-09
GPNIHGFM_00269 1.2e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
GPNIHGFM_00270 1.4e-47 comGC U Required for transformation and DNA binding
GPNIHGFM_00271 1.7e-70 mshD NU general secretion pathway protein
GPNIHGFM_00272 1e-09
GPNIHGFM_00273 5e-78
GPNIHGFM_00276 2e-36 yqgY S Protein of unknown function (DUF2626)
GPNIHGFM_00277 7.5e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
GPNIHGFM_00278 6.6e-08 S Protein of unknown function (DUF2759)
GPNIHGFM_00279 1.9e-152 yqhG S Bacterial protein YqhG of unknown function
GPNIHGFM_00280 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
GPNIHGFM_00281 5.5e-203 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
GPNIHGFM_00282 6.2e-249 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPNIHGFM_00283 6.5e-284 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPNIHGFM_00284 1.9e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
GPNIHGFM_00285 1.8e-153 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
GPNIHGFM_00286 0.0 helD 3.6.4.12 L DNA helicase
GPNIHGFM_00287 2.7e-157 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
GPNIHGFM_00288 2.5e-197 splB 4.1.99.14 L Spore photoproduct lyase
GPNIHGFM_00289 6.5e-75 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
GPNIHGFM_00290 5.4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
GPNIHGFM_00291 4e-55
GPNIHGFM_00292 1.3e-87 yqhR S Conserved membrane protein YqhR
GPNIHGFM_00293 3.3e-192 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
GPNIHGFM_00294 3.2e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPNIHGFM_00295 1e-93 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPNIHGFM_00296 2.4e-47 S YfzA-like protein
GPNIHGFM_00297 1.7e-35 yqhV S Protein of unknown function (DUF2619)
GPNIHGFM_00298 4.6e-166 spoIIIAA S stage III sporulation protein AA
GPNIHGFM_00299 1.1e-81 spoIIIAB S Stage III sporulation protein
GPNIHGFM_00300 4.4e-29 spoIIIAC S stage III sporulation protein AC
GPNIHGFM_00301 1.6e-40 spoIIIAD S Stage III sporulation protein AD
GPNIHGFM_00302 2.5e-201 spoIIIAE S stage III sporulation protein AE
GPNIHGFM_00303 1.7e-89 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
GPNIHGFM_00304 7.6e-99 spoIIIAG S stage III sporulation protein AG
GPNIHGFM_00305 1.7e-88 spoIIIAH S SpoIIIAH-like protein
GPNIHGFM_00306 1.1e-56
GPNIHGFM_00307 1.5e-67 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GPNIHGFM_00308 7.7e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GPNIHGFM_00309 1e-64 yqhY S protein conserved in bacteria
GPNIHGFM_00310 3.3e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPNIHGFM_00311 8.7e-206 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPNIHGFM_00312 9.7e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPNIHGFM_00313 2e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPNIHGFM_00314 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPNIHGFM_00315 2.4e-147 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
GPNIHGFM_00316 1.3e-78 argR K Regulates arginine biosynthesis genes
GPNIHGFM_00317 6.4e-291 recN L May be involved in recombinational repair of damaged DNA
GPNIHGFM_00318 2.3e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
GPNIHGFM_00319 1.8e-142 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
GPNIHGFM_00320 1.3e-107 2.7.8.33, 2.7.8.35 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPNIHGFM_00321 1e-34 yqzF S Protein of unknown function (DUF2627)
GPNIHGFM_00322 0.0 bkdR KT Transcriptional regulator
GPNIHGFM_00323 3.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
GPNIHGFM_00324 1.6e-258 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GPNIHGFM_00325 1.6e-185 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GPNIHGFM_00326 6.9e-181 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GPNIHGFM_00327 1.4e-221 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPNIHGFM_00328 1.4e-74 yqiW S Belongs to the UPF0403 family
GPNIHGFM_00329 7.4e-30 K Cro/C1-type HTH DNA-binding domain
GPNIHGFM_00330 2.3e-50 ansR K Helix-turn-helix XRE-family like proteins
GPNIHGFM_00331 1.7e-30
GPNIHGFM_00332 8.1e-134 yjcH P COG2382 Enterochelin esterase and related enzymes
GPNIHGFM_00333 2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
GPNIHGFM_00334 7.1e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNIHGFM_00335 1.2e-186 dglA S Thiamine-binding protein
GPNIHGFM_00336 6.7e-96
GPNIHGFM_00337 3.4e-141 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPNIHGFM_00338 5.2e-209 thiO 1.4.3.19 E Glycine oxidase
GPNIHGFM_00339 4e-139 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
GPNIHGFM_00340 8.8e-27 thiS H ThiS family
GPNIHGFM_00341 4.5e-109 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GPNIHGFM_00342 2.3e-262 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
GPNIHGFM_00343 1.1e-173 glcK 2.7.1.2 G Glucokinase
GPNIHGFM_00344 5.2e-09 yqgQ S protein conserved in bacteria
GPNIHGFM_00345 4.2e-81
GPNIHGFM_00346 1e-66 yueI S Protein of unknown function (DUF1694)
GPNIHGFM_00347 2.3e-265 spoVAF EG Bacillus/Clostridium GerA spore germination protein
GPNIHGFM_00348 1.4e-292 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
GPNIHGFM_00350 5.6e-229 nhaC C Na H antiporter
GPNIHGFM_00351 7.4e-186 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GPNIHGFM_00352 2.6e-141 S Integral membrane protein DUF92
GPNIHGFM_00353 1.8e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPNIHGFM_00354 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GPNIHGFM_00355 2.5e-124 G PFAM Glycoside hydrolase 15-related
GPNIHGFM_00356 6.9e-60
GPNIHGFM_00357 7.2e-75 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPNIHGFM_00358 0.0 mrdA 3.4.16.4 M penicillin-binding protein
GPNIHGFM_00360 1.3e-232 yqgE EGP Major facilitator superfamily
GPNIHGFM_00361 1.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
GPNIHGFM_00362 8.4e-09
GPNIHGFM_00367 1.7e-272 nptA P COG1283 Na phosphate symporter
GPNIHGFM_00368 3e-133 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNIHGFM_00369 4.3e-41 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNIHGFM_00370 1.5e-113 O NfeD-like C-terminal, partner-binding
GPNIHGFM_00371 9.7e-150 ypuA S Secreted protein
GPNIHGFM_00372 1.3e-173 EGP Major facilitator Superfamily
GPNIHGFM_00373 2.6e-53 fimV NU translation initiation factor activity
GPNIHGFM_00374 2.8e-199 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPNIHGFM_00375 1e-64 yqfX S membrane
GPNIHGFM_00376 3.9e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
GPNIHGFM_00378 1.8e-36 S Domain of Unknown Function (DUF1540)
GPNIHGFM_00379 7.5e-76 zur P Belongs to the Fur family
GPNIHGFM_00380 2.4e-132 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GPNIHGFM_00381 7.7e-143 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GPNIHGFM_00382 5.3e-130 GH23 M Transglycosylase SLT domain
GPNIHGFM_00383 8e-213 pilS 2.7.13.3 T His Kinase A (phosphoacceptor) domain
GPNIHGFM_00384 3.6e-07 yqfT S Protein of unknown function (DUF2624)
GPNIHGFM_00385 4.5e-163 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GPNIHGFM_00386 6.3e-249 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GPNIHGFM_00387 3.1e-44 yqfQ S YqfQ-like protein
GPNIHGFM_00388 8.8e-84 carD K Transcription factor
GPNIHGFM_00389 2e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPNIHGFM_00390 1.1e-190 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPNIHGFM_00391 1.3e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
GPNIHGFM_00392 1.8e-63 C COG2010 Cytochrome c, mono- and diheme variants
GPNIHGFM_00393 1.9e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GPNIHGFM_00394 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GPNIHGFM_00395 6.2e-79 yaiI S Belongs to the UPF0178 family
GPNIHGFM_00396 1.6e-143 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GPNIHGFM_00397 3.8e-111 ccpN K CBS domain
GPNIHGFM_00398 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GPNIHGFM_00399 9.1e-172 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GPNIHGFM_00401 2.2e-137 recO L Involved in DNA repair and RecF pathway recombination
GPNIHGFM_00402 7.1e-18 S YqzL-like protein
GPNIHGFM_00403 2.4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPNIHGFM_00404 5.5e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GPNIHGFM_00405 6.3e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GPNIHGFM_00406 4e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPNIHGFM_00407 0.0 yqfF S membrane-associated HD superfamily hydrolase
GPNIHGFM_00408 5.8e-172 phoH T Phosphate starvation-inducible protein PhoH
GPNIHGFM_00409 8.6e-218 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
GPNIHGFM_00410 6.7e-47 yqfC S sporulation protein YqfC
GPNIHGFM_00411 1.1e-37
GPNIHGFM_00412 2.1e-95 yqfA S UPF0365 protein
GPNIHGFM_00413 1.2e-215 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
GPNIHGFM_00414 5.2e-54 yqeY S Yqey-like protein
GPNIHGFM_00415 2.1e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GPNIHGFM_00416 9.2e-159 yqeW P COG1283 Na phosphate symporter
GPNIHGFM_00417 2.1e-171 iolS C Aldo keto reductase
GPNIHGFM_00418 1.5e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPNIHGFM_00419 6.7e-221 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPNIHGFM_00420 1.7e-134 ycgJ_1 Q ubiE/COQ5 methyltransferase family
GPNIHGFM_00421 9.9e-255 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
GPNIHGFM_00422 3.2e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GPNIHGFM_00423 4.1e-170 prmA J Methylates ribosomal protein L11
GPNIHGFM_00424 2.8e-194 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GPNIHGFM_00425 6.4e-289 dnaK O Heat shock 70 kDa protein
GPNIHGFM_00426 4.2e-69 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPNIHGFM_00427 2e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GPNIHGFM_00428 1.7e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
GPNIHGFM_00429 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GPNIHGFM_00430 4.8e-52
GPNIHGFM_00431 6.1e-200 spoIIP M stage II sporulation protein P
GPNIHGFM_00432 5.1e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GPNIHGFM_00433 4.8e-36 rpsT J Binds directly to 16S ribosomal RNA
GPNIHGFM_00434 1.4e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
GPNIHGFM_00435 2.4e-07 S YqzM-like protein
GPNIHGFM_00436 0.0 comEC S Competence protein ComEC
GPNIHGFM_00437 1e-107 comEB 3.5.4.12 F ComE operon protein 2
GPNIHGFM_00438 2.9e-100 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
GPNIHGFM_00439 4.7e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPNIHGFM_00440 6.9e-133 cmoA S Methyltransferase domain
GPNIHGFM_00441 2.7e-157 cvfB S protein conserved in bacteria
GPNIHGFM_00442 9.8e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GPNIHGFM_00443 6.7e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
GPNIHGFM_00444 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPNIHGFM_00445 5.2e-47 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
GPNIHGFM_00446 6.5e-148 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPNIHGFM_00447 7.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GPNIHGFM_00448 6.2e-96 yqeG S hydrolase of the HAD superfamily
GPNIHGFM_00450 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GPNIHGFM_00451 7.5e-71 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNIHGFM_00452 8.8e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNIHGFM_00453 2e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNIHGFM_00454 1.1e-81 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNIHGFM_00455 3.1e-38 phaF P Multiple resistance and pH regulation protein F (MrpF / PhaF)
GPNIHGFM_00456 6.1e-62 phaG P Na+/H+ antiporter subunit
GPNIHGFM_00457 1.4e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPNIHGFM_00458 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPNIHGFM_00460 2e-257 M Belongs to the BCCT transporter (TC 2.A.15) family
GPNIHGFM_00461 1.4e-220 nasA P COG2223 Nitrate nitrite transporter
GPNIHGFM_00462 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPNIHGFM_00463 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPNIHGFM_00464 9.6e-55 nirD 1.7.1.15 P Nitrite reductase
GPNIHGFM_00465 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPNIHGFM_00466 5.2e-235 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
GPNIHGFM_00467 4.4e-53
GPNIHGFM_00469 6.8e-23 S Histidine kinase
GPNIHGFM_00470 1.6e-24
GPNIHGFM_00471 4.9e-176 yfjD P Transporter associated domain
GPNIHGFM_00472 2.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNIHGFM_00473 7.5e-164 ybaS 1.1.1.58 S Na -dependent transporter
GPNIHGFM_00474 2.5e-222 hipO3 3.5.1.47 S amidohydrolase
GPNIHGFM_00475 1.2e-250 S Membrane
GPNIHGFM_00476 1.5e-186 lplJ 6.3.1.20 H Lipoate-protein ligase
GPNIHGFM_00477 1.3e-103 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GPNIHGFM_00478 1.7e-54 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPNIHGFM_00479 0.0 malS 3.2.1.1 GH13 G Carbohydrate binding domain
GPNIHGFM_00480 7.8e-106 arpR K Bacterial regulatory proteins, tetR family
GPNIHGFM_00481 2.6e-145 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00482 2e-155 EP N-terminal TM domain of oligopeptide transport permease C
GPNIHGFM_00483 4.4e-141 oppD P Oligopeptide/dipeptide transporter, C-terminal region
GPNIHGFM_00484 2.5e-147 appF P ATPases associated with a variety of cellular activities
GPNIHGFM_00485 8.3e-290 E Bacterial extracellular solute-binding proteins, family 5 Middle
GPNIHGFM_00486 1.1e-77 M1-460
GPNIHGFM_00487 1.1e-10 S YrhC-like protein
GPNIHGFM_00488 8.9e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPNIHGFM_00489 6e-149 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GPNIHGFM_00490 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
GPNIHGFM_00491 1.1e-11 S Protein of unknown function (DUF1510)
GPNIHGFM_00492 4.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPNIHGFM_00493 5.3e-113 udk 2.7.1.48 F Cytidine monophosphokinase
GPNIHGFM_00494 2.4e-113 yrrM 2.1.1.104 S O-methyltransferase
GPNIHGFM_00495 1.2e-208 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPNIHGFM_00496 4.1e-25 yrzB S Belongs to the UPF0473 family
GPNIHGFM_00497 5.7e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPNIHGFM_00498 3.2e-43 yrzL S Belongs to the UPF0297 family
GPNIHGFM_00499 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPNIHGFM_00500 5.6e-184 yrrI S AI-2E family transporter
GPNIHGFM_00501 2.1e-30 yrzR
GPNIHGFM_00502 3e-81 yrrD S protein conserved in bacteria
GPNIHGFM_00503 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GPNIHGFM_00504 4.5e-67 S COG0457 FOG TPR repeat
GPNIHGFM_00505 2.5e-216 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GPNIHGFM_00506 2.2e-210 iscS 2.8.1.7 E Cysteine desulfurase
GPNIHGFM_00507 2.8e-70 cymR K Transcriptional regulator
GPNIHGFM_00508 1.2e-230 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
GPNIHGFM_00509 7.2e-107 rsfA S Transcriptional regulator
GPNIHGFM_00510 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
GPNIHGFM_00511 2e-216 yxjG 2.1.1.14 E Methionine synthase
GPNIHGFM_00512 4e-50
GPNIHGFM_00513 6.9e-215 1.1.1.3 E homoserine dehydrogenase
GPNIHGFM_00514 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GPNIHGFM_00515 1e-240 hisS 6.1.1.21 J histidyl-tRNA synthetase
GPNIHGFM_00517 1.3e-201 V Belongs to the UPF0214 family
GPNIHGFM_00518 1.1e-192 S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_00519 3.6e-142 thuA G Trehalose utilisation
GPNIHGFM_00520 9e-184 cytR 5.1.1.1 K LacI family transcriptional regulator
GPNIHGFM_00521 6.3e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GPNIHGFM_00522 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPNIHGFM_00523 1.2e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPNIHGFM_00524 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
GPNIHGFM_00525 2.9e-37 yrvD S Lipopolysaccharide assembly protein A domain
GPNIHGFM_00526 2.7e-142 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPNIHGFM_00527 6.7e-232 secD U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPNIHGFM_00528 9.6e-22 yrzD S Post-transcriptional regulator
GPNIHGFM_00529 4.7e-248 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPNIHGFM_00530 2.1e-25 yodI
GPNIHGFM_00531 5.2e-70 ycaP S membrane
GPNIHGFM_00532 3.2e-57 yrzE S Protein of unknown function (DUF3792)
GPNIHGFM_00533 2.5e-37 yajC U Preprotein translocase subunit YajC
GPNIHGFM_00534 3.4e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GPNIHGFM_00535 4e-187 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPNIHGFM_00536 1.4e-27 yrzS S Protein of unknown function (DUF2905)
GPNIHGFM_00537 5.8e-183 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GPNIHGFM_00538 4.6e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GPNIHGFM_00539 3.4e-86 bofC S BofC C-terminal domain
GPNIHGFM_00540 9.4e-62 1.9.3.1 C cytochrome c oxidase subunit II
GPNIHGFM_00541 1.5e-22 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPNIHGFM_00542 2.2e-105 safA M spore coat assembly protein SafA
GPNIHGFM_00543 6.9e-206 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPNIHGFM_00544 5.9e-144 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
GPNIHGFM_00545 3.2e-273 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
GPNIHGFM_00546 6e-205 nifS 2.8.1.7 E Cysteine desulfurase
GPNIHGFM_00547 1.6e-87 niaR S small molecule binding protein (contains 3H domain)
GPNIHGFM_00548 2.1e-160 pheA 4.2.1.51 E Prephenate dehydratase
GPNIHGFM_00549 1.8e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
GPNIHGFM_00550 7.6e-220 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPNIHGFM_00551 1.3e-99 spo0B T Sporulation initiation phospho-transferase B, C-terminal
GPNIHGFM_00553 7e-256 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GPNIHGFM_00554 1.1e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GPNIHGFM_00555 3.8e-201 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPNIHGFM_00556 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPNIHGFM_00557 4.1e-122 ccdA O cytochrome c biogenesis protein
GPNIHGFM_00558 2.3e-125 ecsC S EcsC protein family
GPNIHGFM_00559 5.2e-210 ecsB U ABC transporter
GPNIHGFM_00560 7.1e-138 ecsA V transporter (ATP-binding protein)
GPNIHGFM_00561 1.2e-73 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GPNIHGFM_00562 7.7e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPNIHGFM_00563 5.1e-49 yhaH D gas vesicle protein
GPNIHGFM_00564 1e-107 hpr K Negative regulator of protease production and sporulation
GPNIHGFM_00565 4e-102 S Protein conserved in bacteria
GPNIHGFM_00567 2.2e-161 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GPNIHGFM_00568 4.4e-43 yhaL S Sporulation protein YhaL
GPNIHGFM_00569 8e-182 yhaM L Shows a 3'-5' exoribonuclease activity
GPNIHGFM_00570 8.5e-257 T PhoQ Sensor
GPNIHGFM_00571 1.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNIHGFM_00572 1.3e-40
GPNIHGFM_00574 1.3e-156 yhaX S hydrolases of the HAD superfamily
GPNIHGFM_00575 1.4e-54 yheA S Belongs to the UPF0342 family
GPNIHGFM_00576 2.6e-203 yheB S Belongs to the UPF0754 family
GPNIHGFM_00577 1.2e-16 yheE S Family of unknown function (DUF5342)
GPNIHGFM_00578 4.1e-22
GPNIHGFM_00579 8.6e-159 lrp QT PucR C-terminal helix-turn-helix domain
GPNIHGFM_00580 2.6e-205 msmK P Belongs to the ABC transporter superfamily
GPNIHGFM_00581 1.4e-78 K Sigma-70, region 4
GPNIHGFM_00582 3.4e-214
GPNIHGFM_00584 9.8e-283 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GPNIHGFM_00585 5.7e-130 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
GPNIHGFM_00586 4.1e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
GPNIHGFM_00587 2.1e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
GPNIHGFM_00588 8.5e-218 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
GPNIHGFM_00589 7.2e-95 lemA S LemA family
GPNIHGFM_00590 2.1e-149 htpX O Peptidase family M48
GPNIHGFM_00591 1.5e-230 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNIHGFM_00592 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNIHGFM_00593 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNIHGFM_00594 2.7e-271 ycgB S Stage V sporulation protein R
GPNIHGFM_00595 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
GPNIHGFM_00596 4.2e-300 glpD 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
GPNIHGFM_00597 7.5e-121 sfsA S Sugar fermentation stimulation protein
GPNIHGFM_00598 7.1e-305 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GPNIHGFM_00599 4.6e-288 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
GPNIHGFM_00600 3.4e-132 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GPNIHGFM_00601 4e-113 ycgM Q Fumarylacetoacetate (FAA) hydrolase family
GPNIHGFM_00602 9e-220 mtnE 2.6.1.83 E Aminotransferase
GPNIHGFM_00603 9.7e-127 frp 1.5.1.39 C Oxidoreductase
GPNIHGFM_00604 1.5e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GPNIHGFM_00605 7.7e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPNIHGFM_00606 3.7e-131 yvoA K transcriptional
GPNIHGFM_00608 1.5e-264 4.3.2.1 E argininosuccinate lyase
GPNIHGFM_00609 1.1e-124 K UTRA
GPNIHGFM_00610 1.1e-248 E Sodium:solute symporter family
GPNIHGFM_00611 3.5e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_00612 1.9e-237 3.2.1.51, 4.2.2.23 GH95,PL11 G Right handed beta helix region
GPNIHGFM_00613 2e-80 S Protein of unknown function (DUF664)
GPNIHGFM_00615 1.6e-146 drrB V Transport permease protein
GPNIHGFM_00616 1.1e-173 drrA V COG1131 ABC-type multidrug transport system, ATPase component
GPNIHGFM_00617 4.7e-266 EGP Major facilitator Superfamily
GPNIHGFM_00618 2.3e-141 K Bacterial regulatory proteins, tetR family
GPNIHGFM_00621 6.7e-215 yhbH S Belongs to the UPF0229 family
GPNIHGFM_00622 1.1e-138 cysA1 S AAA domain
GPNIHGFM_00623 2.4e-101 sipV 3.4.21.89 U Belongs to the peptidase S26 family
GPNIHGFM_00624 6.3e-86 sipV 3.4.21.89 U Belongs to the peptidase S26 family
GPNIHGFM_00625 0.0 prkA T Ser protein kinase
GPNIHGFM_00626 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
GPNIHGFM_00627 2.8e-51 hmoB 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
GPNIHGFM_00628 4.3e-87 yufK S Family of unknown function (DUF5366)
GPNIHGFM_00629 4.3e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GPNIHGFM_00630 1.1e-166 yhbB S Putative amidase domain
GPNIHGFM_00631 2.2e-76 K Acetyltransferase (GNAT) domain
GPNIHGFM_00632 2.9e-93 ogt 1.17.99.6, 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPNIHGFM_00633 3.2e-217 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPNIHGFM_00634 6e-97 S B3/4 domain
GPNIHGFM_00635 5e-81 dps P Belongs to the Dps family
GPNIHGFM_00636 2.1e-196 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
GPNIHGFM_00637 1.2e-105
GPNIHGFM_00638 5.9e-118 V ATPases associated with a variety of cellular activities
GPNIHGFM_00639 1.8e-60 yhcF K Transcriptional regulator
GPNIHGFM_00640 2e-103 S ABC-2 family transporter protein
GPNIHGFM_00641 4.5e-166 yhcH V ABC transporter, ATP-binding protein
GPNIHGFM_00642 3.8e-90 mepB S MepB protein
GPNIHGFM_00643 7e-150 rhaR2 K helix_turn_helix, arabinose operon control protein
GPNIHGFM_00644 1.7e-265 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
GPNIHGFM_00645 0.0 bglX 3.2.1.21 GH3 G Belongs to the glycosyl hydrolase 3 family
GPNIHGFM_00646 3e-254 scrA5 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNIHGFM_00647 7.6e-203 pamO 1.14.13.22 P Flavin-binding monooxygenase-like
GPNIHGFM_00648 9.4e-256 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNIHGFM_00649 3.9e-87
GPNIHGFM_00650 2.9e-97 S Peptidase propeptide and YPEB domain
GPNIHGFM_00651 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
GPNIHGFM_00652 1.1e-205 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
GPNIHGFM_00653 1.4e-81 G Tripartite ATP-independent periplasmic transporters, DctQ component
GPNIHGFM_00654 2.5e-181 G Bacterial extracellular solute-binding protein, family 7
GPNIHGFM_00655 1.3e-168 K helix_turn _helix lactose operon repressor
GPNIHGFM_00656 2.2e-134 K helix_turn_helix, mercury resistance
GPNIHGFM_00657 0.0 msbA2 3.6.3.44 V ABC transporter
GPNIHGFM_00658 8.2e-146 ybbH_2 K Transcriptional regulator
GPNIHGFM_00659 3.1e-181 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
GPNIHGFM_00660 5.3e-237 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
GPNIHGFM_00661 1.5e-167 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
GPNIHGFM_00663 4.4e-286 K Propionate catabolism activator
GPNIHGFM_00664 8e-152 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPNIHGFM_00665 7e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNIHGFM_00666 2e-189 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
GPNIHGFM_00667 5.1e-179 purR15 K Bacterial regulatory proteins, lacI family
GPNIHGFM_00668 2e-274 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPNIHGFM_00669 9.6e-151 ypbG 2.7.1.2 GK ROK family
GPNIHGFM_00670 1.4e-140 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00671 1.2e-161 P COG0395 ABC-type sugar transport system, permease component
GPNIHGFM_00672 8e-214 G Bacterial extracellular solute-binding protein
GPNIHGFM_00673 4.9e-139 manA3 3.2.1.78 GH26 G Endoglucanase
GPNIHGFM_00674 1e-35 S Protein of unknown function (DUF2642)
GPNIHGFM_00675 4.2e-12
GPNIHGFM_00676 1.5e-97 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GPNIHGFM_00677 8e-137 1.6.5.5 C alcohol dehydrogenase
GPNIHGFM_00678 3.2e-77 K Transcriptional regulator
GPNIHGFM_00679 2.4e-53 fdx5 C 2Fe-2S iron-sulfur cluster binding domain
GPNIHGFM_00680 5.9e-20
GPNIHGFM_00681 3.2e-298 KT Transcriptional regulator
GPNIHGFM_00682 6.8e-215 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
GPNIHGFM_00683 2.2e-222 EG COG2610 H gluconate symporter and related permeases
GPNIHGFM_00684 4.3e-172 glsA 3.5.1.2 E Belongs to the glutaminase family
GPNIHGFM_00685 1.6e-197 eutG C alcohol dehydrogenase
GPNIHGFM_00686 4.7e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNIHGFM_00687 2e-261 EG Bacillus/Clostridium GerA spore germination protein
GPNIHGFM_00688 8.1e-51
GPNIHGFM_00689 1e-87 ectA 2.3.1.178 K L-2,4-diaminobutyric acid acetyltransferase
GPNIHGFM_00690 1e-245 ectB 2.6.1.76 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPNIHGFM_00691 9.5e-76 ectC 4.2.1.108 S Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
GPNIHGFM_00692 1.9e-247 G Glycerol-3-phosphate ABC transporter substrate-binding protein
GPNIHGFM_00693 4.1e-147 G Xylose isomerase-like TIM barrel
GPNIHGFM_00694 1.9e-164 G ABC transporter (permease)
GPNIHGFM_00695 3.2e-147 ugpE P PFAM binding-protein-dependent transport systems inner membrane component
GPNIHGFM_00696 1.2e-194 3.6.3.20 P Belongs to the ABC transporter superfamily
GPNIHGFM_00698 1.2e-235 KLT Protein kinase domain
GPNIHGFM_00701 3.9e-76 H Tellurite resistance protein TehB
GPNIHGFM_00702 5e-50 S ABC-2 family transporter protein
GPNIHGFM_00704 7.6e-310 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPNIHGFM_00705 1.1e-269 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
GPNIHGFM_00706 1.3e-202 vraB 2.3.1.9 I Belongs to the thiolase family
GPNIHGFM_00707 2.6e-91 S response regulator aspartate phosphatase
GPNIHGFM_00709 1.6e-36 S Family of unknown function (DUF5344)
GPNIHGFM_00710 9.6e-80 S SMI1-KNR4 cell-wall
GPNIHGFM_00712 1.5e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNIHGFM_00713 5.5e-189 araC2 K Arabinose-binding domain of AraC transcription regulator, N-term
GPNIHGFM_00715 4.4e-74 nsrR K Transcriptional regulator
GPNIHGFM_00716 7.5e-233 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPNIHGFM_00717 0.0 glpQ1 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
GPNIHGFM_00718 4.1e-198 ugpC 3.6.3.20 P Belongs to the ABC transporter superfamily
GPNIHGFM_00719 1.8e-162 ugpA G ABC transporter (permease)
GPNIHGFM_00720 3.5e-138 ugpE P Glycerol-3-phosphate ABC transporter permease
GPNIHGFM_00721 2.9e-230 ugpB G Glycerol-3-phosphate ABC transporter substrate-binding protein
GPNIHGFM_00722 7.3e-138 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GPNIHGFM_00723 6.1e-208 yceL EGP Major Facilitator Superfamily
GPNIHGFM_00724 5.4e-308 G Bacterial extracellular solute-binding protein
GPNIHGFM_00725 8.2e-148 3.1.3.41 G Haloacid dehalogenase-like hydrolase
GPNIHGFM_00726 1.6e-91 K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GPNIHGFM_00727 1.8e-173 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00728 2.8e-157 G COG0395 ABC-type sugar transport system, permease component
GPNIHGFM_00729 5.4e-119 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GPNIHGFM_00730 9.1e-175 G Xylose isomerase-like TIM barrel
GPNIHGFM_00731 3.4e-194 S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_00732 2.3e-99 ykoP G polysaccharide deacetylase
GPNIHGFM_00733 7.5e-158
GPNIHGFM_00734 3.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_00735 1.9e-139 K helix_turn_helix, arabinose operon control protein
GPNIHGFM_00736 2e-64 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNIHGFM_00737 6.2e-168 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
GPNIHGFM_00738 9.2e-251 yhdG E amino acid
GPNIHGFM_00739 3.3e-175 K AraC-like ligand binding domain
GPNIHGFM_00740 0.0 rhaA 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
GPNIHGFM_00741 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
GPNIHGFM_00742 4.8e-51 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
GPNIHGFM_00743 9.5e-223 iolF EGP Major facilitator Superfamily
GPNIHGFM_00744 3.6e-146 K AraC-like ligand binding domain
GPNIHGFM_00745 7.4e-230 MA20_16885 S Oxidoreductase family, NAD-binding Rossmann fold
GPNIHGFM_00746 1.6e-216 MA20_16880 EM Protein of unknown function (DUF993)
GPNIHGFM_00747 7.6e-157 MA20_16875 G Xylose isomerase-like TIM barrel
GPNIHGFM_00748 1.1e-209 S Oxidoreductase family, NAD-binding Rossmann fold
GPNIHGFM_00749 2.9e-310 2.7.13.3 T Histidine kinase
GPNIHGFM_00750 4.1e-198 T helix_turn_helix, arabinose operon control protein
GPNIHGFM_00751 1.1e-247 G Bacterial extracellular solute-binding protein
GPNIHGFM_00752 2.5e-175 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00753 9.6e-155 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00754 6.1e-194 I Acyltransferase family
GPNIHGFM_00755 4.7e-233 arlS T His Kinase A (phosphoacceptor) domain
GPNIHGFM_00756 3.7e-117 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNIHGFM_00757 1.7e-125 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
GPNIHGFM_00759 1.3e-55
GPNIHGFM_00760 0.0 E cell wall organization
GPNIHGFM_00761 1.5e-236 G Bacterial extracellular solute-binding protein
GPNIHGFM_00762 9.9e-153 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00763 6e-157 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00764 5.1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
GPNIHGFM_00765 5.9e-241 G Bacterial extracellular solute-binding protein
GPNIHGFM_00766 6.7e-159 amyD G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00767 1.2e-152 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00768 2.4e-102 S Protein of unknown function, DUF624
GPNIHGFM_00769 1.5e-169 M1-640 K Transcriptional regulator
GPNIHGFM_00770 5.4e-164 rhaR1 K AraC-like ligand binding domain
GPNIHGFM_00771 9.6e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
GPNIHGFM_00772 4e-215 egsA 1.1.1.261 C Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
GPNIHGFM_00773 7.1e-135 araD 4.1.2.17, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
GPNIHGFM_00774 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
GPNIHGFM_00775 6.7e-281 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
GPNIHGFM_00776 3.8e-196 chvE G ABC transporter
GPNIHGFM_00777 3e-279 araG 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
GPNIHGFM_00778 1.7e-194 gguB G Belongs to the binding-protein-dependent transport system permease family
GPNIHGFM_00779 5.3e-297 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
GPNIHGFM_00781 2.7e-88
GPNIHGFM_00783 9.3e-78 S Putative small multi-drug export protein
GPNIHGFM_00784 2.8e-107 V Transport permease protein
GPNIHGFM_00785 7.2e-178 KTV LytTr DNA-binding domain
GPNIHGFM_00786 3.8e-48 sugE P Small Multidrug Resistance protein
GPNIHGFM_00787 3.2e-59 sugE P Small Multidrug Resistance protein
GPNIHGFM_00788 1.9e-98 yvdT K Transcriptional regulator
GPNIHGFM_00789 2.8e-239 EGP Major Facilitator Superfamily
GPNIHGFM_00790 5.9e-135 iolR K COG1349 Transcriptional regulators of sugar metabolism
GPNIHGFM_00791 4.4e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNIHGFM_00792 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
GPNIHGFM_00793 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
GPNIHGFM_00794 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
GPNIHGFM_00795 2.3e-178 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
GPNIHGFM_00796 1.4e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
GPNIHGFM_00797 4.5e-163 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
GPNIHGFM_00798 1.3e-190 yisS 1.1.1.370 S Oxidoreductase family, NAD-binding Rossmann fold
GPNIHGFM_00799 4.7e-272 yidK S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPNIHGFM_00800 1.3e-103 S Protein of unknown function (DUF421)
GPNIHGFM_00801 8.1e-246 metY 2.5.1.49 E O-acetylhomoserine
GPNIHGFM_00802 1.3e-62 S Putative zinc- or iron-chelating domain
GPNIHGFM_00803 2.4e-142 bxlB G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00804 1.7e-165 bxlC G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_00805 8.4e-251 bxlD G Bacterial extracellular solute-binding protein
GPNIHGFM_00807 1.1e-161 K AraC-like ligand binding domain
GPNIHGFM_00808 9.3e-189 yjjN E Alcohol dehydrogenase GroES-like domain
GPNIHGFM_00809 2.1e-188 dctP G Bacterial extracellular solute-binding protein, family 7
GPNIHGFM_00810 6.8e-81 G Tripartite ATP-independent periplasmic transporters, DctQ component
GPNIHGFM_00811 2.1e-222 G Tripartite ATP-independent periplasmic transporter, DctM component
GPNIHGFM_00812 6.2e-290 uxaA 4.2.1.7 G Altronate
GPNIHGFM_00813 1.8e-289 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
GPNIHGFM_00814 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 K transcriptional regulator, MtlR
GPNIHGFM_00815 2.3e-159 4.1.2.13 G Fructose-bisphosphate aldolase class-II
GPNIHGFM_00816 4.4e-77 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GPNIHGFM_00817 1.1e-47 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
GPNIHGFM_00818 3.3e-168 fruA2 G Phosphotransferase System
GPNIHGFM_00819 4.1e-92 5.3.1.15 S Cupin 2, conserved barrel domain protein
GPNIHGFM_00821 4e-267 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNIHGFM_00822 3e-159 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GPNIHGFM_00823 9.1e-104 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GPNIHGFM_00824 2e-250 KT Transcriptional regulator
GPNIHGFM_00825 3.7e-233 E Acyclic terpene utilisation family protein AtuA
GPNIHGFM_00826 3.4e-49
GPNIHGFM_00827 7.2e-218 C Citrate transporter
GPNIHGFM_00828 1.9e-234 NT chemotaxis protein
GPNIHGFM_00829 3.1e-235 V MatE
GPNIHGFM_00830 9.6e-40
GPNIHGFM_00831 9.1e-98 S Tetratricopeptide repeat
GPNIHGFM_00832 3e-66 3.6.1.55 F NUDIX domain
GPNIHGFM_00833 5.8e-56
GPNIHGFM_00834 1.5e-28
GPNIHGFM_00835 1.8e-51
GPNIHGFM_00836 4.6e-188 uxuA 4.2.1.8 G mannonate dehydratase activity
GPNIHGFM_00837 5.3e-184 S Tripartite tricarboxylate transporter family receptor
GPNIHGFM_00838 3.9e-260 S Tripartite tricarboxylate transporter TctA family
GPNIHGFM_00839 1.4e-79 S Tripartite tricarboxylate transporter TctB family
GPNIHGFM_00840 1.1e-254 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNIHGFM_00841 8e-171 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
GPNIHGFM_00842 9.1e-119 ycbG K FCD
GPNIHGFM_00843 1.1e-113 K FCD
GPNIHGFM_00844 1.8e-202 yeaN P COG2807 Cyanate permease
GPNIHGFM_00845 4.4e-62 cdd_2 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
GPNIHGFM_00846 1.3e-73 K Transcriptional regulator
GPNIHGFM_00847 1.2e-146 3.4.16.4 V Beta-lactamase
GPNIHGFM_00848 8.8e-113 yybG S Pentapeptide repeat-containing protein
GPNIHGFM_00849 4.2e-44 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPNIHGFM_00850 1.6e-233 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPNIHGFM_00851 1.4e-48 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPNIHGFM_00852 9.9e-274 gmuD 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPNIHGFM_00853 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
GPNIHGFM_00854 1.6e-90 K Bacterial transcription activator, effector binding domain
GPNIHGFM_00855 2.3e-84
GPNIHGFM_00856 1.8e-20 ypbG 2.7.1.2 GK ROK family
GPNIHGFM_00857 6.3e-97 yocH 3.5.1.28 M 3D domain
GPNIHGFM_00858 2e-215 2.3.1.157, 2.7.7.23 JM Bacterial transferase hexapeptide (six repeats)
GPNIHGFM_00859 2e-129 K transcriptional
GPNIHGFM_00860 1.7e-139 S carbohydrate derivative metabolic process
GPNIHGFM_00862 5.4e-250 I radical SAM domain protein
GPNIHGFM_00863 1.3e-284 H Involved in the biosynthesis of porphyrin-containing compound
GPNIHGFM_00864 6.2e-11
GPNIHGFM_00865 3.3e-138 yafE Q methyltransferase
GPNIHGFM_00866 6.9e-14 1.2.7.12 S Uncharacterised protein family UPF0066
GPNIHGFM_00867 6.8e-89 1.2.7.12 S Uncharacterised protein family UPF0066
GPNIHGFM_00868 1.9e-223 EGP Major facilitator Superfamily
GPNIHGFM_00869 2.6e-100 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GPNIHGFM_00870 5e-173 wbpP 5.1.3.2, 5.1.3.7 M GDP-mannose 4,6 dehydratase
GPNIHGFM_00871 1.8e-128 M Glycosyl transferases group 1
GPNIHGFM_00872 2.7e-101
GPNIHGFM_00873 1.2e-102 GT2,GT4 M transferase activity, transferring glycosyl groups
GPNIHGFM_00874 1.1e-119 M transferase activity, transferring glycosyl groups
GPNIHGFM_00875 5.2e-114 M Glycosyl transferase family 2
GPNIHGFM_00876 6e-236 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPNIHGFM_00877 6.1e-66 VPA1573 J acetyltransferase
GPNIHGFM_00878 1.6e-198 M Glycosyltransferase like family 2
GPNIHGFM_00879 1.1e-35 S Protein of unknown function (DUF2642)
GPNIHGFM_00880 9.3e-24
GPNIHGFM_00881 8.5e-240 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
GPNIHGFM_00882 2.9e-92 ycsK E anatomical structure formation involved in morphogenesis
GPNIHGFM_00883 6.1e-121 K helix_turn_helix isocitrate lyase regulation
GPNIHGFM_00884 4.4e-164 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
GPNIHGFM_00885 1.1e-102 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
GPNIHGFM_00886 2.2e-226 dgoD 4.2.1.6 M Belongs to the mandelate racemase muconate lactonizing enzyme family
GPNIHGFM_00887 2.3e-195 gntU EG COG2610 H gluconate symporter and related permeases
GPNIHGFM_00888 3e-153 S Metallo-beta-lactamase superfamily
GPNIHGFM_00889 1.8e-86 S Predicted membrane protein (DUF2243)
GPNIHGFM_00890 2.8e-119 S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
GPNIHGFM_00891 1.8e-232 T COG0642 Signal transduction histidine kinase
GPNIHGFM_00892 4.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNIHGFM_00893 3.5e-167 4.2.1.103 K DJ-1/PfpI family
GPNIHGFM_00894 5.4e-110 S Predicted membrane protein (DUF2306)
GPNIHGFM_00895 6.8e-201 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
GPNIHGFM_00896 9.9e-66 S VanZ like family
GPNIHGFM_00897 2.6e-109 wrbA 1.6.5.2 S Belongs to the WrbA family
GPNIHGFM_00899 2.7e-82 2.3.1.128 K Acetyltransferase (GNAT) family
GPNIHGFM_00900 9.1e-128 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GPNIHGFM_00901 0.0 V SNF2 family N-terminal domain
GPNIHGFM_00902 7.4e-09 S Domain of unknown function (DUF5082)
GPNIHGFM_00903 3.3e-08 S Family of unknown function (DUF5344)
GPNIHGFM_00904 1.9e-244 S LXG domain of WXG superfamily
GPNIHGFM_00905 7.4e-88
GPNIHGFM_00907 2.3e-101 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GPNIHGFM_00908 3.4e-155 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPNIHGFM_00910 7.8e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPNIHGFM_00911 2.6e-06 lig1
GPNIHGFM_00912 2.1e-74 ylqH S FlhB HrpN YscU SpaS Family
GPNIHGFM_00913 1.1e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
GPNIHGFM_00914 9.7e-169 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GPNIHGFM_00915 8.6e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
GPNIHGFM_00916 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPNIHGFM_00917 2.1e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GPNIHGFM_00918 1.7e-165 xerC L tyrosine recombinase XerC
GPNIHGFM_00919 2.3e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPNIHGFM_00920 2.1e-223 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPNIHGFM_00921 4.1e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GPNIHGFM_00922 3.3e-65 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
GPNIHGFM_00923 1.8e-72 flgC N Belongs to the flagella basal body rod proteins family
GPNIHGFM_00924 9.7e-38 fliE N Flagellar hook-basal body
GPNIHGFM_00925 1e-234 fliF N The M ring may be actively involved in energy transduction
GPNIHGFM_00926 1.5e-175 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GPNIHGFM_00927 2.9e-73 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
GPNIHGFM_00928 1.4e-245 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
GPNIHGFM_00929 5.4e-40 fliJ N bacterial-type flagellum organization
GPNIHGFM_00931 1e-205 N Flagellar hook-length control protein FliK
GPNIHGFM_00932 1.2e-71 flgD N Flagellar basal body rod modification protein
GPNIHGFM_00933 1.4e-139 flgG N Flagellar basal body rod
GPNIHGFM_00934 1.5e-27 flbD N protein, possibly involved in motility
GPNIHGFM_00935 4.1e-69 fliL N Controls the rotational direction of flagella during chemotaxis
GPNIHGFM_00936 2e-175 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GPNIHGFM_00937 1.3e-205 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPNIHGFM_00938 1.2e-58 cheY T cheY-homologous receiver domain
GPNIHGFM_00939 1.3e-103 fliZ N Flagellar biosynthesis protein, FliO
GPNIHGFM_00940 6.2e-112 fliP N Plays a role in the flagellum-specific transport system
GPNIHGFM_00941 3.6e-39 fliQ N Role in flagellar biosynthesis
GPNIHGFM_00942 2.9e-129 fliR N Flagellar biosynthetic protein FliR
GPNIHGFM_00943 5.5e-187 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPNIHGFM_00944 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPNIHGFM_00945 1.4e-173 flhF N Flagellar biosynthesis regulator FlhF
GPNIHGFM_00946 4.9e-94
GPNIHGFM_00947 4.9e-160 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
GPNIHGFM_00948 1.9e-104 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
GPNIHGFM_00949 4.3e-83 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
GPNIHGFM_00950 4.9e-134 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNIHGFM_00952 1.5e-132 rpsB J Belongs to the universal ribosomal protein uS2 family
GPNIHGFM_00953 6.3e-149 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPNIHGFM_00954 1.6e-123 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GPNIHGFM_00955 2.1e-89 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GPNIHGFM_00956 2.4e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPNIHGFM_00957 1.6e-130 cdsA 2.7.7.41 S Belongs to the CDS family
GPNIHGFM_00958 1.1e-206 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
GPNIHGFM_00959 7.1e-231 rasP M zinc metalloprotease
GPNIHGFM_00960 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GPNIHGFM_00961 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPNIHGFM_00962 2.8e-79 rimP S Required for maturation of 30S ribosomal subunits
GPNIHGFM_00963 5e-196 nusA K Participates in both transcription termination and antitermination
GPNIHGFM_00964 1e-41 ylxR K nucleic-acid-binding protein implicated in transcription termination
GPNIHGFM_00965 1.6e-46 ylxQ J ribosomal protein
GPNIHGFM_00966 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPNIHGFM_00967 8.9e-41 ylxP S protein conserved in bacteria
GPNIHGFM_00968 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPNIHGFM_00969 7.1e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPNIHGFM_00970 1e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GPNIHGFM_00971 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPNIHGFM_00972 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GPNIHGFM_00973 3.5e-188 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
GPNIHGFM_00974 6.9e-218 pepR S Belongs to the peptidase M16 family
GPNIHGFM_00975 1.2e-35 ymxH S YlmC YmxH family
GPNIHGFM_00976 4.4e-158 spoVFA E subunit a
GPNIHGFM_00977 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
GPNIHGFM_00978 7.9e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPNIHGFM_00979 2.7e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
GPNIHGFM_00980 7.7e-155 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPNIHGFM_00981 1.1e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPNIHGFM_00982 3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
GPNIHGFM_00983 8.4e-10 S YlzJ-like protein
GPNIHGFM_00984 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GPNIHGFM_00985 4.9e-128 ymfC K Transcriptional regulator
GPNIHGFM_00986 1.9e-226 ymfF S Peptidase M16
GPNIHGFM_00987 4.4e-244 ymfH S zinc protease
GPNIHGFM_00988 7.2e-119 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_00989 1.3e-38 ymfJ S Protein of unknown function (DUF3243)
GPNIHGFM_00990 4.6e-140 ymfK S Protein of unknown function (DUF3388)
GPNIHGFM_00991 2.7e-123 ymfM S protein conserved in bacteria
GPNIHGFM_00992 8.7e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPNIHGFM_00993 1.7e-224 cinA 3.5.1.42 S Belongs to the CinA family
GPNIHGFM_00994 6.7e-290 deaD 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GPNIHGFM_00995 3.3e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPNIHGFM_00996 1.3e-187 L Calcineurin-like phosphoesterase superfamily domain
GPNIHGFM_00997 5.3e-254 sbcC L AAA domain
GPNIHGFM_00999 1.7e-114 L DNA recombination
GPNIHGFM_01000 1.8e-218 rny S Endoribonuclease that initiates mRNA decay
GPNIHGFM_01001 6.7e-150 ymdB S protein conserved in bacteria
GPNIHGFM_01002 6.7e-38 spoVS S Stage V sporulation protein S
GPNIHGFM_01003 7.2e-152 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
GPNIHGFM_01004 6.7e-303 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPNIHGFM_01005 7.3e-55 ymcA 3.6.3.21 S Belongs to the UPF0342 family
GPNIHGFM_01006 2.6e-103 cotE S Spore coat protein
GPNIHGFM_01007 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPNIHGFM_01008 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPNIHGFM_01009 2.2e-134 J Putative SAM-dependent methyltransferase
GPNIHGFM_01010 8.3e-168 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPNIHGFM_01011 2.7e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
GPNIHGFM_01012 7.6e-183 xerD L Belongs to the 'phage' integrase family
GPNIHGFM_01013 5.8e-169 spoVK O stage V sporulation protein K
GPNIHGFM_01014 5.3e-245 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
GPNIHGFM_01015 3.1e-264 glnA 6.3.1.2 E glutamine synthetase
GPNIHGFM_01016 3.5e-220 glcE C FAD binding domain
GPNIHGFM_01017 1.4e-251 glcF C Glycolate oxidase
GPNIHGFM_01018 2e-272 glcD 1.1.2.4, 1.1.3.15 C FAD linked oxidases, C-terminal domain
GPNIHGFM_01019 0.0 glcB 2.3.3.9 C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GPNIHGFM_01020 3.9e-139 Q Domain of unknown function (DUF2437)
GPNIHGFM_01021 2.3e-136 K helix_turn_helix isocitrate lyase regulation
GPNIHGFM_01022 1.9e-47
GPNIHGFM_01023 7.3e-92 MA20_21960 FG Domain of unknown function (DUF4269)
GPNIHGFM_01025 1e-212 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPNIHGFM_01027 2.7e-219 yuxJ EGP Major facilitator Superfamily
GPNIHGFM_01028 2.6e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPNIHGFM_01030 3.4e-115 yneB L resolvase
GPNIHGFM_01031 4.2e-34 ynzC S UPF0291 protein
GPNIHGFM_01032 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPNIHGFM_01033 2e-71 yneE S Sporulation inhibitor of replication protein sirA
GPNIHGFM_01034 7.9e-29 yneF S UPF0154 protein
GPNIHGFM_01035 0.0 mdlA V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNIHGFM_01036 0.0 mdlB V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNIHGFM_01037 3.9e-81 yneK S Protein of unknown function (DUF2621)
GPNIHGFM_01038 9.4e-13
GPNIHGFM_01040 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GPNIHGFM_01043 1.2e-11 sspN S Small acid-soluble spore protein N family
GPNIHGFM_01044 2.2e-139 P Copper resistance protein D
GPNIHGFM_01045 0.0 spoVK O stage V sporulation protein K
GPNIHGFM_01046 2.9e-75 S thioesterase
GPNIHGFM_01047 9.4e-153 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GPNIHGFM_01048 1.7e-79 S Domain of unknown function (DUF4352)
GPNIHGFM_01049 2.3e-178 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GPNIHGFM_01050 3.6e-146 I Hydrolase
GPNIHGFM_01051 1e-237 ykuI T Diguanylate phosphodiesterase
GPNIHGFM_01052 1.7e-22
GPNIHGFM_01053 1.6e-25 S YppG-like protein
GPNIHGFM_01054 5.3e-69 hspX O Belongs to the small heat shock protein (HSP20) family
GPNIHGFM_01055 1.3e-168 3.4.13.19 E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
GPNIHGFM_01056 1.5e-158 cheV 2.7.13.3 T Chemotaxis protein CheV
GPNIHGFM_01058 1.1e-49 yneR S Belongs to the HesB IscA family
GPNIHGFM_01059 1.7e-87 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPNIHGFM_01060 6.5e-210 I COG0657 Esterase lipase
GPNIHGFM_01061 1.7e-43 S DNA alkylation repair protein
GPNIHGFM_01062 1.7e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
GPNIHGFM_01063 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPNIHGFM_01064 5.2e-110 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
GPNIHGFM_01065 4.8e-51 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
GPNIHGFM_01066 9.6e-43 ywcE S Required for proper spore morphogenesis. Important for spore germination
GPNIHGFM_01067 1.4e-38 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GPNIHGFM_01068 4.3e-245 agcS E Sodium alanine symporter
GPNIHGFM_01069 5.7e-233 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
GPNIHGFM_01070 2.8e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPNIHGFM_01071 4.5e-76 queD 4.1.2.50, 4.2.3.12 H synthase
GPNIHGFM_01072 1.9e-119 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GPNIHGFM_01073 1.5e-94 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPNIHGFM_01074 5.2e-102 KT LuxR family transcriptional regulator
GPNIHGFM_01075 3.7e-183 T Histidine kinase
GPNIHGFM_01076 3.3e-113 S ABC-2 type transporter
GPNIHGFM_01077 6.4e-123 V ABC-2 type transporter
GPNIHGFM_01078 1.4e-167 V COG1131 ABC-type multidrug transport system, ATPase component
GPNIHGFM_01080 0.0 topB1 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPNIHGFM_01081 9.8e-74 osmC O redox protein, regulator of disulfide bond formation
GPNIHGFM_01083 1e-116 M lytic transglycosylase activity
GPNIHGFM_01084 3.7e-185 2.1.1.163, 2.1.1.201 Q O-methyltransferase
GPNIHGFM_01086 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
GPNIHGFM_01087 1.7e-176 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
GPNIHGFM_01088 5.4e-32 yozC
GPNIHGFM_01089 1.3e-301 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GPNIHGFM_01090 2.2e-156 S reductase
GPNIHGFM_01091 0.0 recQ 3.6.4.12 L DNA helicase
GPNIHGFM_01092 2.9e-54 ytxJ O Protein of unknown function (DUF2847)
GPNIHGFM_01093 4.7e-90 yocC
GPNIHGFM_01094 4.6e-102 speG J Acetyltransferase (GNAT) domain
GPNIHGFM_01095 3.5e-163 polA 2.7.7.7 L Helix-hairpin-helix class 2 (Pol1 family) motifs
GPNIHGFM_01096 8.2e-125 bshB2 S deacetylase
GPNIHGFM_01097 1.3e-60 yojF S Protein of unknown function (DUF1806)
GPNIHGFM_01098 5.4e-112 mucD 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPNIHGFM_01099 7.4e-68 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
GPNIHGFM_01101 3e-212 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
GPNIHGFM_01102 2.7e-162 S membrane
GPNIHGFM_01103 1.3e-144 K SIR2-like domain
GPNIHGFM_01104 2.6e-107 S recombinase activity
GPNIHGFM_01105 2e-24
GPNIHGFM_01106 2.9e-45 E IrrE N-terminal-like domain
GPNIHGFM_01108 2.6e-38
GPNIHGFM_01109 2e-21 K Helix-turn-helix XRE-family like proteins
GPNIHGFM_01110 2.6e-16 yqaF K Helix-turn-helix XRE-family like proteins
GPNIHGFM_01111 9.3e-62
GPNIHGFM_01117 3.2e-50 bet L RecT family
GPNIHGFM_01119 1.6e-10 xkdB K sequence-specific DNA binding
GPNIHGFM_01123 1.4e-39 S HNH endonuclease
GPNIHGFM_01124 6e-52 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GPNIHGFM_01127 3.8e-40 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPNIHGFM_01128 7.8e-42 K BRO family, N-terminal domain
GPNIHGFM_01129 4.2e-15 S Phage-like element PBSX protein XtrA
GPNIHGFM_01132 3.5e-30 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GPNIHGFM_01133 9.4e-45
GPNIHGFM_01134 3.4e-14
GPNIHGFM_01137 9e-64 L DNA packaging
GPNIHGFM_01138 7.1e-180 ps334 S Terminase-like family
GPNIHGFM_01139 1.2e-146 S Phage portal protein, SPP1 Gp6-like
GPNIHGFM_01140 3.7e-59 S Phage Mu protein F like protein
GPNIHGFM_01142 6e-50 S Domain of unknown function (DUF4355)
GPNIHGFM_01143 2.1e-37
GPNIHGFM_01144 2.2e-137 S Phage major capsid protein E
GPNIHGFM_01146 7.4e-20 S Phage gp6-like head-tail connector protein
GPNIHGFM_01147 1.2e-07
GPNIHGFM_01148 1.5e-28 S Bacteriophage HK97-gp10, putative tail-component
GPNIHGFM_01149 1.4e-18 S Protein of unknown function (DUF3168)
GPNIHGFM_01150 2.2e-38 N domain, Protein
GPNIHGFM_01151 9e-22 S Phage tail assembly chaperone protein, TAC
GPNIHGFM_01152 5.1e-84 D Phage tail tape measure protein TP901
GPNIHGFM_01153 2.1e-30 S Phage tail protein
GPNIHGFM_01154 1.8e-42 L Prophage endopeptidase tail
GPNIHGFM_01157 1.3e-130 S outer membrane
GPNIHGFM_01160 1.6e-20 xhlA S Haemolysin XhlA
GPNIHGFM_01161 8.3e-23 S Bacteriophage A118-like holin, Hol118
GPNIHGFM_01162 1e-108 3.5.1.28 M Ami_3
GPNIHGFM_01163 1.1e-31
GPNIHGFM_01164 1.8e-146 UW nuclease activity
GPNIHGFM_01165 1.8e-90 O ATPase family associated with various cellular activities (AAA)
GPNIHGFM_01166 5.3e-192 O Subtilase family
GPNIHGFM_01167 3.6e-10
GPNIHGFM_01169 1e-68 L Metallo-beta-lactamase superfamily
GPNIHGFM_01171 3.4e-56 S YolD-like protein
GPNIHGFM_01172 2.2e-13
GPNIHGFM_01174 2e-112 drgA C nitroreductase
GPNIHGFM_01175 1.3e-60 K helix_turn_helix, mercury resistance
GPNIHGFM_01176 4.4e-115 P Pyridine nucleotide-disulphide oxidoreductase
GPNIHGFM_01177 1.4e-08
GPNIHGFM_01178 7.1e-133 ycsF S Belongs to the UPF0271 (lamB) family
GPNIHGFM_01179 1.1e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
GPNIHGFM_01180 4.3e-178 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
GPNIHGFM_01181 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
GPNIHGFM_01182 5e-267 G Bacterial extracellular solute-binding protein
GPNIHGFM_01183 5.6e-172 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01184 4.6e-160 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01185 1.7e-136 K helix_turn_helix, mercury resistance
GPNIHGFM_01186 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GPNIHGFM_01187 1.1e-123 MA20_01270 K AraC family transcriptional regulator
GPNIHGFM_01188 1.3e-90 J Acetyltransferase (GNAT) domain
GPNIHGFM_01189 4.6e-20 tnpC
GPNIHGFM_01190 3.4e-23 tnpB L Belongs to the 'phage' integrase family
GPNIHGFM_01192 2.9e-77
GPNIHGFM_01193 7e-75 tpiA 2.7.2.3, 5.1.3.39, 5.3.1.1, 5.3.1.33 J Triosephosphate isomerase
GPNIHGFM_01194 3.1e-51 rpiB 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15, 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
GPNIHGFM_01195 1e-52 rpiB 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15, 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
GPNIHGFM_01196 1.1e-120 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
GPNIHGFM_01197 3.5e-73 Z012_00995 5.3.1.15 S Pfam:DUF1498
GPNIHGFM_01198 3.3e-131 G Phosphotransferase system, EIIC
GPNIHGFM_01199 7.2e-34 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
GPNIHGFM_01200 2.2e-49 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GPNIHGFM_01201 1.8e-132 4.1.2.13 G Fructose-bisphosphate aldolase class-II
GPNIHGFM_01202 8.9e-62 K DeoR C terminal sensor domain
GPNIHGFM_01203 6e-252 gltD 1.3.1.1 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
GPNIHGFM_01204 5.5e-231 preA 1.3.1.1 CF dihydroorotate dehydrogenase
GPNIHGFM_01205 2.3e-270 hyuA 3.5.2.2 F Amidohydrolase family
GPNIHGFM_01206 4.4e-07
GPNIHGFM_01207 6.8e-234 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GPNIHGFM_01208 6e-260 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPNIHGFM_01209 6.1e-62 F PFAM AIG2 family protein
GPNIHGFM_01210 3.6e-42 S Integral membrane protein
GPNIHGFM_01211 9.7e-226 K helix_turn_helix, arabinose operon control protein
GPNIHGFM_01212 2.1e-256 S Hypothetical glycosyl hydrolase 6
GPNIHGFM_01213 4.1e-225 G Bacterial extracellular solute-binding protein
GPNIHGFM_01214 9.3e-129 G ABC transporter permease
GPNIHGFM_01215 1.1e-146 G ABC-type polysaccharide transport system, permease component
GPNIHGFM_01216 3.3e-273 3.2.1.23 G beta-galactosidase
GPNIHGFM_01217 3.9e-239 S Hypothetical glycosyl hydrolase 6
GPNIHGFM_01218 2.2e-109 glxR 1.1.1.31, 1.1.1.60 I 3-hydroxyisobutyrate dehydrogenase
GPNIHGFM_01221 1.4e-167 S Tetratricopeptide repeat
GPNIHGFM_01222 6.8e-276 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 T Domain present in phytochromes and cGMP-specific phosphodiesterases.
GPNIHGFM_01223 1.3e-265 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNIHGFM_01224 3.4e-152 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
GPNIHGFM_01225 1.9e-128 S Protein of unknown function (DUF3100)
GPNIHGFM_01226 3.5e-71 S An automated process has identified a potential problem with this gene model
GPNIHGFM_01227 4.2e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
GPNIHGFM_01228 2.2e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
GPNIHGFM_01229 1.6e-115 ywqC M biosynthesis protein
GPNIHGFM_01230 2.6e-169 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
GPNIHGFM_01231 1.7e-79 S Tetratrico peptide repeat
GPNIHGFM_01232 5.1e-81 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
GPNIHGFM_01233 1.1e-93 yjbB G Transmembrane secretion effector
GPNIHGFM_01234 9.4e-223 rodA D Belongs to the SEDS family
GPNIHGFM_01235 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GPNIHGFM_01236 7.4e-161 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
GPNIHGFM_01237 6.4e-44 HA62_12640 S GCN5-related N-acetyl-transferase
GPNIHGFM_01238 4.8e-224
GPNIHGFM_01239 1.5e-241 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPNIHGFM_01240 9e-218 lytE M NlpC/P60 family
GPNIHGFM_01242 7.1e-16 Q N-acetyltransferase
GPNIHGFM_01243 3.2e-78 yisT S DinB family
GPNIHGFM_01244 1.2e-89 speG_2 2.3.1.57 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GPNIHGFM_01245 1.3e-290 pip S YhgE Pip N-terminal domain protein
GPNIHGFM_01246 4.7e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPNIHGFM_01247 2.4e-136 estA S Putative esterase
GPNIHGFM_01248 6.5e-108 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPNIHGFM_01249 1.9e-187 S Spore germination B3/ GerAC like, C-terminal
GPNIHGFM_01250 1e-196 E Spore germination protein
GPNIHGFM_01251 2.6e-272 P Spore gernimation protein GerA
GPNIHGFM_01252 3.2e-59 epuA S DNA-directed RNA polymerase subunit beta
GPNIHGFM_01253 7.1e-136 flhP N flagellar basal body
GPNIHGFM_01254 4.2e-136 flhO N flagellar basal body
GPNIHGFM_01255 1.6e-180 mbl D Rod shape-determining protein
GPNIHGFM_01256 3.6e-45 spoIIID K Stage III sporulation protein D
GPNIHGFM_01257 4.4e-44 ykkD P Multidrug resistance protein
GPNIHGFM_01258 7.4e-53 sugE P Multidrug resistance protein
GPNIHGFM_01259 1.9e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
GPNIHGFM_01260 1.1e-187 spoIID D Stage II sporulation protein D
GPNIHGFM_01261 2.6e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPNIHGFM_01262 1.5e-21 ywmB S TATA-box binding
GPNIHGFM_01263 7e-55 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GPNIHGFM_01264 4.2e-264 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPNIHGFM_01265 9.2e-153 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPNIHGFM_01266 1.8e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPNIHGFM_01267 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPNIHGFM_01268 1.3e-31 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPNIHGFM_01269 1.4e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPNIHGFM_01270 2.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
GPNIHGFM_01271 7.3e-12 S ATP synthase I chain
GPNIHGFM_01272 5.7e-22 atpI S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
GPNIHGFM_01273 0.0 vpr O Belongs to the peptidase S8 family
GPNIHGFM_01274 5.7e-88 panZ K -acetyltransferase
GPNIHGFM_01275 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPNIHGFM_01276 5.3e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPNIHGFM_01277 5.7e-92 ywlG S Belongs to the UPF0340 family
GPNIHGFM_01278 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
GPNIHGFM_01279 2.2e-118 mcpA NT Chemotaxis
GPNIHGFM_01280 3.7e-70 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPNIHGFM_01281 3.7e-91 mntP P Probably functions as a manganese efflux pump
GPNIHGFM_01282 2.9e-152 csbX EGP Major facilitator Superfamily
GPNIHGFM_01283 1.3e-99 5.3.1.5 M Xylose isomerase-like TIM barrel
GPNIHGFM_01284 5.8e-46 K Helix-turn-helix domain, rpiR family
GPNIHGFM_01285 7.8e-70 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPNIHGFM_01286 1.2e-61 S Regulator of ribonuclease activity B
GPNIHGFM_01287 5.4e-179 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GPNIHGFM_01288 4.4e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
GPNIHGFM_01289 1.4e-113 spoIIR S stage II sporulation protein R
GPNIHGFM_01290 1.7e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GPNIHGFM_01291 9.6e-176 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPNIHGFM_01292 1.8e-253 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GPNIHGFM_01293 9.3e-74
GPNIHGFM_01294 9.3e-109 tdk 2.7.1.21 F thymidine kinase
GPNIHGFM_01295 3.8e-40 rpmE2 J Ribosomal protein L31
GPNIHGFM_01296 1.3e-235 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPNIHGFM_01297 9.2e-178 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
GPNIHGFM_01298 8.1e-206 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPNIHGFM_01299 2.8e-114 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPNIHGFM_01300 3.8e-159 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
GPNIHGFM_01301 5.5e-59 spo0F T response regulator
GPNIHGFM_01302 1.2e-86 ywjG S Domain of unknown function (DUF2529)
GPNIHGFM_01303 3.5e-307 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GPNIHGFM_01304 1.1e-57 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GPNIHGFM_01305 7.2e-107 kstR2_2 K Transcriptional regulator
GPNIHGFM_01306 2.5e-206 mmgC I acyl-CoA dehydrogenase
GPNIHGFM_01307 3.9e-148 hbdA 1.1.1.157 I Dehydrogenase
GPNIHGFM_01308 5e-210 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
GPNIHGFM_01309 0.0 fadF C COG0247 Fe-S oxidoreductase
GPNIHGFM_01310 7.5e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
GPNIHGFM_01311 8e-74 yqgC S protein conserved in bacteria
GPNIHGFM_01312 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GPNIHGFM_01313 1e-75 ywiB S protein conserved in bacteria
GPNIHGFM_01314 6e-168 speB 3.5.3.11 E Belongs to the arginase family
GPNIHGFM_01315 4.8e-159 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GPNIHGFM_01316 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPNIHGFM_01317 3.8e-156 vipF 2.3.1.128 K Acetyltransferase (GNAT) domain
GPNIHGFM_01318 0.0 pepF E oligoendopeptidase F
GPNIHGFM_01319 1.9e-98 ywhD S YwhD family
GPNIHGFM_01320 8.5e-199 F S-adenosylhomocysteine deaminase activity
GPNIHGFM_01321 1.2e-123 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
GPNIHGFM_01322 5.6e-26 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
GPNIHGFM_01323 2.8e-43 cotF M Spore coat protein
GPNIHGFM_01325 2.5e-89 ywgA 2.1.1.72, 3.1.21.3
GPNIHGFM_01326 6e-249 ywfO S COG1078 HD superfamily phosphohydrolases
GPNIHGFM_01327 2.1e-190 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPNIHGFM_01328 2.8e-143 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
GPNIHGFM_01329 1.4e-181 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
GPNIHGFM_01330 6.2e-140 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
GPNIHGFM_01331 3e-144 ywfI C May function as heme-dependent peroxidase
GPNIHGFM_01332 4.8e-132 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPNIHGFM_01333 5.8e-48
GPNIHGFM_01334 2.6e-180 yhaP CP COG1668 ABC-type Na efflux pump, permease component
GPNIHGFM_01335 1.4e-164 yhaQ S ABC transporter, ATP-binding protein
GPNIHGFM_01336 8.4e-162 natA1 V ABC transporter
GPNIHGFM_01337 1.2e-62 K helix_turn_helix gluconate operon transcriptional repressor
GPNIHGFM_01338 9.6e-127
GPNIHGFM_01339 2.4e-77 cwlJ 3.5.1.28 M Cell wall
GPNIHGFM_01340 9.8e-77 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
GPNIHGFM_01341 1.3e-58 ywdK S small membrane protein
GPNIHGFM_01342 1.7e-108 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNIHGFM_01343 5.1e-268 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPNIHGFM_01344 1.2e-46 S Family of unknown function (DUF5327)
GPNIHGFM_01345 3.3e-132 dnaQ2 2.7.7.7 L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
GPNIHGFM_01346 1.4e-167 2.7.7.7 T Putative nucleotidyltransferase substrate binding domain
GPNIHGFM_01347 2.5e-228 amtB P Ammonium transporter
GPNIHGFM_01348 8.4e-177 abrB S Pfam:AmoA
GPNIHGFM_01349 8.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPNIHGFM_01350 4.5e-231 BH2250 S protein conserved in bacteria
GPNIHGFM_01351 4e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPNIHGFM_01352 1e-276 hutH 4.3.1.3 E Histidine ammonia-lyase
GPNIHGFM_01353 3.4e-47 S Branched-chain amino acid transport protein (AzlD)
GPNIHGFM_01354 1.9e-122 azlC E AzlC protein
GPNIHGFM_01355 2.8e-24 gntR9 K Alanine-glyoxylate amino-transferase
GPNIHGFM_01356 1.6e-32 bceB V ABC transporter (permease)
GPNIHGFM_01357 3.4e-245 S dienelactone hydrolase
GPNIHGFM_01358 9e-264 6.3.1.2 E Glutamine synthetase, catalytic domain
GPNIHGFM_01359 5.6e-72 S Protein of unknown function (DUF4064)
GPNIHGFM_01360 5e-76 K Acetyltransferase (GNAT) domain
GPNIHGFM_01361 1.5e-259 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GPNIHGFM_01362 6.6e-73 bdbA CO Thioredoxin
GPNIHGFM_01363 4.7e-70 bdbC O Required for disulfide bond formation in some proteins
GPNIHGFM_01364 3.6e-285 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
GPNIHGFM_01366 6.6e-82 yuaF OU Membrane protein implicated in regulation of membrane protease activity
GPNIHGFM_01367 1.5e-152 yuaG 3.4.21.72 S protein conserved in bacteria
GPNIHGFM_01368 1.2e-129 map 3.4.11.18 E Methionine aminopeptidase
GPNIHGFM_01369 2.2e-246 3.1.3.1 P Belongs to the alkaline phosphatase family
GPNIHGFM_01370 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPNIHGFM_01371 8.4e-221 ywbD 2.1.1.191 J Methyltransferase
GPNIHGFM_01372 2.2e-42 ydzA EGP Major facilitator Superfamily
GPNIHGFM_01373 6e-55 yflT S Heat induced stress protein YflT
GPNIHGFM_01374 3.7e-99 S UPF0302 domain
GPNIHGFM_01375 1.5e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
GPNIHGFM_01376 1.9e-159 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GPNIHGFM_01377 4.6e-140 troB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GPNIHGFM_01378 1.4e-173 troA P Belongs to the bacterial solute-binding protein 9 family
GPNIHGFM_01380 3.8e-145 ycsE 3.1.3.104 S hydrolases of the HAD superfamily
GPNIHGFM_01381 6e-247 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
GPNIHGFM_01382 6.4e-218 S Acetyltransferase
GPNIHGFM_01383 4.3e-238 NT chemotaxis protein
GPNIHGFM_01384 0.0 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPNIHGFM_01385 2.7e-211 yxlH EGP Major facilitator Superfamily
GPNIHGFM_01386 3.2e-95 S DinB superfamily
GPNIHGFM_01387 4.5e-311 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
GPNIHGFM_01388 0.0 ywjA V ABC transporter
GPNIHGFM_01389 2.4e-170 murB 1.3.1.98 M cell wall formation
GPNIHGFM_01390 1.1e-107 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GPNIHGFM_01391 3.4e-107 yrbG3 S membrane
GPNIHGFM_01392 1.2e-163 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GPNIHGFM_01394 5.7e-22
GPNIHGFM_01395 4e-139 mta K TipAS antibiotic-recognition domain
GPNIHGFM_01396 1.3e-168 O Predicted Zn-dependent protease (DUF2268)
GPNIHGFM_01397 2e-103 K GrpB protein
GPNIHGFM_01398 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPNIHGFM_01399 5.2e-75 yosT L Bacterial transcription activator, effector binding domain
GPNIHGFM_01400 5.5e-113
GPNIHGFM_01401 4.4e-118
GPNIHGFM_01402 5.3e-176 S Phosphotransferase system, EIIC
GPNIHGFM_01403 4.5e-131 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPNIHGFM_01404 1.1e-92 tag 3.2.2.20 L Methyladenine glycosylase
GPNIHGFM_01405 6.3e-128
GPNIHGFM_01406 9.1e-95 3.4.21.89 U Signal peptidase
GPNIHGFM_01407 0.0 vpr O Belongs to the peptidase S8 family
GPNIHGFM_01408 8.6e-153 hisJ3 3.1.3.15 E PHP domain
GPNIHGFM_01409 4.5e-183 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
GPNIHGFM_01410 6.8e-113 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPNIHGFM_01411 2.7e-119
GPNIHGFM_01412 1.1e-195 yetN S Protein of unknown function (DUF3900)
GPNIHGFM_01413 3.9e-185 cdaR KT Sugar diacid utilization regulator
GPNIHGFM_01414 1.6e-200 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GPNIHGFM_01415 2.9e-07
GPNIHGFM_01416 7.1e-80 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GPNIHGFM_01417 9.6e-146 map 3.4.11.18 E Methionine aminopeptidase
GPNIHGFM_01418 1.6e-79 yvbK 3.1.3.25 K acetyltransferase
GPNIHGFM_01419 2.4e-242 aspT EK Alanine-glyoxylate amino-transferase
GPNIHGFM_01420 2.7e-88 3.1.1.29 K -acetyltransferase
GPNIHGFM_01421 3e-54
GPNIHGFM_01422 1.8e-75 K transcriptional
GPNIHGFM_01423 8.1e-188 mgtE P Acts as a magnesium transporter
GPNIHGFM_01424 3.4e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNIHGFM_01425 1.2e-189 desK 2.7.13.3 T Histidine kinase
GPNIHGFM_01426 1.1e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
GPNIHGFM_01427 1.6e-168 agpT K AraC-like ligand binding domain
GPNIHGFM_01428 4.6e-249 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
GPNIHGFM_01429 5.8e-108 dedA 3.1.3.1 S SNARE associated Golgi protein
GPNIHGFM_01430 2.7e-100 yvrI K RNA polymerase
GPNIHGFM_01431 1.7e-38
GPNIHGFM_01432 3.9e-159 U Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01433 8.2e-171 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01434 1.5e-220 T cheY-homologous receiver domain
GPNIHGFM_01435 6.3e-299 2.7.13.3 T Histidine kinase
GPNIHGFM_01436 0.0 G Bacterial extracellular solute-binding protein
GPNIHGFM_01437 4.9e-123 ywiC S YwiC-like protein
GPNIHGFM_01438 3.2e-270 narK P COG2223 Nitrate nitrite transporter
GPNIHGFM_01439 5e-111 nreC T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNIHGFM_01440 1.4e-195 nreB 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
GPNIHGFM_01441 2.7e-82 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
GPNIHGFM_01442 1.7e-125 narI 1.7.5.1 C nitrate reductase, gamma subunit
GPNIHGFM_01443 4.2e-115 narJ C Nitrate reductase delta subunit
GPNIHGFM_01444 0.0 narH 1.7.5.1 C Nitrate reductase, beta
GPNIHGFM_01445 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPNIHGFM_01446 4.2e-79 scdA D Di-iron-containing protein involved in the repair of iron-sulfur clusters
GPNIHGFM_01447 3.3e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GPNIHGFM_01448 9.9e-283 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNIHGFM_01449 1e-114 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GPNIHGFM_01450 3.7e-140 K Helix-turn-helix domain, rpiR family
GPNIHGFM_01451 1.8e-87 K Transcriptional regulator PadR-like family
GPNIHGFM_01452 5e-39 Q FtsX-like permease family
GPNIHGFM_01453 0.0 Q FtsX-like permease family
GPNIHGFM_01454 3.5e-129 lolD-2 V COG1136 ABC-type antimicrobial peptide transport system, ATPase component
GPNIHGFM_01456 5.7e-19
GPNIHGFM_01458 1e-15
GPNIHGFM_01459 4.7e-170 glcA G Glycoside hydrolase family 16
GPNIHGFM_01462 3.5e-51
GPNIHGFM_01465 7.1e-07
GPNIHGFM_01468 3.1e-07
GPNIHGFM_01469 4.9e-08
GPNIHGFM_01470 6.3e-09 S LXG domain of WXG superfamily
GPNIHGFM_01471 1.9e-07
GPNIHGFM_01472 1.8e-09 S nuclease activity
GPNIHGFM_01473 8.9e-07
GPNIHGFM_01474 9.7e-238 S nuclease activity
GPNIHGFM_01475 2e-46
GPNIHGFM_01476 1.9e-47
GPNIHGFM_01477 8.3e-45
GPNIHGFM_01478 3.9e-70 S Family of unknown function (DUF5383)
GPNIHGFM_01479 0.0 esaA S domain protein
GPNIHGFM_01480 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GPNIHGFM_01481 2e-212 essB S WXG100 protein secretion system (Wss), protein YukC
GPNIHGFM_01482 7.2e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
GPNIHGFM_01483 1.2e-48 esxA S Belongs to the WXG100 family
GPNIHGFM_01484 3.3e-158 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01485 1.7e-146 M1-465 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01486 2.3e-245 ugpB1 G Bacterial extracellular solute-binding protein
GPNIHGFM_01487 9.7e-174 agpT K AraC-like ligand binding domain
GPNIHGFM_01488 3e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
GPNIHGFM_01489 3.5e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
GPNIHGFM_01490 4.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
GPNIHGFM_01491 0.0 hscC O Hsp70 protein
GPNIHGFM_01492 0.0 O DnaJ molecular chaperone homology domain
GPNIHGFM_01493 3.5e-227 yhfW G Metalloenzyme superfamily
GPNIHGFM_01494 2.3e-215 yhfX E Alanine racemase, N-terminal domain
GPNIHGFM_01495 8.6e-204 2.9.1.1 E Cys/Met metabolism PLP-dependent enzyme
GPNIHGFM_01496 1.4e-172 php S Phosphotriesterase family
GPNIHGFM_01497 3.7e-222 yhfT S Protein of unknown function
GPNIHGFM_01498 1.7e-57 yhfU S Protein of unknown function DUF2620
GPNIHGFM_01499 3.6e-55 S PRD domain
GPNIHGFM_01500 4.8e-160 3.13.1.3 P YhfZ C-terminal domain
GPNIHGFM_01501 7.9e-191 pslL G Acyltransferase family
GPNIHGFM_01502 7e-124 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPNIHGFM_01503 5.6e-247 argE 3.5.1.16 E Acetylornithine deacetylase
GPNIHGFM_01505 6.6e-229 lacE3 G PFAM extracellular solute-binding protein family 1
GPNIHGFM_01506 9.6e-156 cebF P PFAM binding-protein-dependent transport systems inner membrane component
GPNIHGFM_01507 5.7e-152 araQ5 P PFAM binding-protein-dependent transport systems inner membrane component
GPNIHGFM_01508 4.6e-215 gntP EG GntP family permease
GPNIHGFM_01509 1.2e-185 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
GPNIHGFM_01510 1.4e-234 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
GPNIHGFM_01511 5.4e-133 ygbI K DeoR C terminal sensor domain
GPNIHGFM_01512 7.2e-270 gerKA EG Spore germination protein
GPNIHGFM_01513 7.3e-209 gerKC S spore germination
GPNIHGFM_01515 3.5e-200 E Spore germination protein
GPNIHGFM_01516 3.3e-155 kynA 1.13.11.11 E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
GPNIHGFM_01517 7.6e-112 kynB 3.5.1.9 S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
GPNIHGFM_01518 8.1e-238 kynU 3.7.1.3 E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
GPNIHGFM_01519 1.7e-204 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GPNIHGFM_01520 4.2e-220 ybfB G COG0477 Permeases of the major facilitator superfamily
GPNIHGFM_01521 4.5e-50 S Protein of unknown function (DUF1093)
GPNIHGFM_01523 0.0 chiA 3.2.1.14 GH18 G Glycoside Hydrolase Family 18
GPNIHGFM_01524 1e-136 K UTRA
GPNIHGFM_01525 1.1e-133 chbG 2.7.1.196, 2.7.1.205, 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
GPNIHGFM_01526 2.3e-243 celF 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GPNIHGFM_01527 2.8e-238 ywbA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPNIHGFM_01528 2.1e-49 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPNIHGFM_01529 4.1e-44 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPNIHGFM_01530 5.9e-121 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GPNIHGFM_01531 5e-91
GPNIHGFM_01532 2.6e-156 arsB P Arsenic resistance protein
GPNIHGFM_01533 4.6e-128 MA20_32325 3.4.17.11 E Peptidase dimerisation domain
GPNIHGFM_01534 4.4e-83 K Helix-turn-helix domain, rpiR family
GPNIHGFM_01535 6.7e-198 ycgA S C4-dicarboxylate anaerobic carrier
GPNIHGFM_01536 1e-228 cstA T Carbon starvation protein
GPNIHGFM_01537 7.9e-20 XK27_00085 K Helix-turn-helix domain
GPNIHGFM_01538 5.4e-28
GPNIHGFM_01539 1.4e-172 ybcL EGP Major facilitator Superfamily
GPNIHGFM_01540 2.7e-103 tetR K Bacterial regulatory proteins, tetR family
GPNIHGFM_01541 1.7e-102 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GPNIHGFM_01542 2.2e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNIHGFM_01543 2.2e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
GPNIHGFM_01544 4.1e-188 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
GPNIHGFM_01545 1.7e-271 C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
GPNIHGFM_01546 1.5e-189 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
GPNIHGFM_01547 8.6e-167 yraN K Transcriptional regulator
GPNIHGFM_01548 2e-208 S Tripartite tricarboxylate transporter family receptor
GPNIHGFM_01549 1.6e-261 S Tripartite tricarboxylate transporter TctA family
GPNIHGFM_01550 1.4e-64 S Tripartite tricarboxylate transporter TctB family
GPNIHGFM_01551 2.8e-213 mii 5.3.3.6 S PrpF protein
GPNIHGFM_01552 9.7e-59 gntR1 K GntR family transcriptional regulator
GPNIHGFM_01553 2.7e-152 V ABC transporter
GPNIHGFM_01554 1.4e-21
GPNIHGFM_01555 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
GPNIHGFM_01556 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPNIHGFM_01557 5.6e-99 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
GPNIHGFM_01558 3.4e-138 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 C CbiX
GPNIHGFM_01559 2e-261 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
GPNIHGFM_01560 1.6e-111 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
GPNIHGFM_01561 2.5e-184 cysP P phosphate transporter
GPNIHGFM_01562 1.2e-216 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
GPNIHGFM_01563 3.1e-138 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
GPNIHGFM_01564 3.2e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
GPNIHGFM_01565 2e-92 K Transcriptional regulator PadR-like family
GPNIHGFM_01566 5.7e-127 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
GPNIHGFM_01567 4.6e-132 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GPNIHGFM_01568 1.4e-209 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
GPNIHGFM_01569 2.9e-171 P ABC transporter substrate-binding protein
GPNIHGFM_01570 8.2e-83 ssuE 1.5.1.38 S FMN reductase
GPNIHGFM_01572 2e-74
GPNIHGFM_01573 1.7e-119 S protein conserved in bacteria
GPNIHGFM_01574 5.1e-146 2.7.1.196, 2.7.1.205 K sequence-specific DNA binding
GPNIHGFM_01575 5e-230 gntT EG gluconate transmembrane transporter activity
GPNIHGFM_01577 4.4e-242
GPNIHGFM_01578 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPNIHGFM_01579 1.9e-43 M1-594 S Thiamine-binding protein
GPNIHGFM_01580 6.3e-205 chrA P chromate transporter, chromate ion transporter
GPNIHGFM_01581 3.1e-30 dmpI 5.3.2.6 S Tautomerase enzyme
GPNIHGFM_01582 2.1e-195 EGP Major facilitator Superfamily
GPNIHGFM_01583 2.6e-172 E Thermophilic metalloprotease (M29)
GPNIHGFM_01584 9.2e-113 aroM E AroM protein
GPNIHGFM_01585 3.8e-160 S Protein of unknown function (DUF1177)
GPNIHGFM_01586 7.6e-186 S Protein of unknown function (DUF917)
GPNIHGFM_01587 1.4e-284 S OPT oligopeptide transporter protein
GPNIHGFM_01588 1.3e-106 hyuE 5.1.99.3 E Asp/Glu/Hydantoin racemase
GPNIHGFM_01589 6.4e-274 KT PucR C-terminal helix-turn-helix domain
GPNIHGFM_01590 5.7e-222 yrbE S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_01591 6.3e-122 MA20_14010 S Trehalose utilisation
GPNIHGFM_01592 2.3e-215 xylR GK ROK family
GPNIHGFM_01593 1.9e-197 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
GPNIHGFM_01594 1.4e-278 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G xylulose kinase
GPNIHGFM_01595 1.3e-259 xylA 5.3.1.5 G Belongs to the xylose isomerase family
GPNIHGFM_01596 3.1e-136 K Transcriptional regulator
GPNIHGFM_01597 8.1e-243 3.5.1.18 E Acetylornithine deacetylase
GPNIHGFM_01598 1.8e-173 S Protein of unknown function (DUF1177)
GPNIHGFM_01599 8.3e-190 ddpF E Belongs to the ABC transporter superfamily
GPNIHGFM_01600 2.1e-185 oppD P Belongs to the ABC transporter superfamily
GPNIHGFM_01601 1.4e-259 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GPNIHGFM_01602 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GPNIHGFM_01603 2.1e-91 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPNIHGFM_01604 4.1e-67 pbuO_1 S permease
GPNIHGFM_01605 4.4e-20 pbuO_1 S Permease
GPNIHGFM_01606 2.9e-168 pilS 2.7.13.3 F GHKL domain
GPNIHGFM_01607 3.9e-168 yqjA S Putative aromatic acid exporter C-terminal domain
GPNIHGFM_01608 4.4e-94 yqjB S protein conserved in bacteria
GPNIHGFM_01610 5.1e-69 5.1.99.1 E COG0346 Lactoylglutathione lyase and related lyases
GPNIHGFM_01611 6.2e-194 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
GPNIHGFM_01612 2.1e-95 3.5.1.104 G Polysaccharide deacetylase
GPNIHGFM_01614 7.1e-69 yaaR S protein conserved in bacteria
GPNIHGFM_01615 2.3e-78 3.6.1.55 S Pfam Polyketide cyclase dehydrase and lipid transport
GPNIHGFM_01616 2e-74 ykuL S CBS domain
GPNIHGFM_01617 0.0 apr O Belongs to the peptidase S8 family
GPNIHGFM_01618 9.1e-139 yibQ S protein conserved in bacteria
GPNIHGFM_01619 3.4e-46 tnrA K transcriptional
GPNIHGFM_01620 3.2e-49
GPNIHGFM_01622 4.7e-244 lysC 2.7.2.4 E Belongs to the aspartokinase family
GPNIHGFM_01623 2.9e-121 P Polycystin cation channel
GPNIHGFM_01624 8.8e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPNIHGFM_01625 1.9e-223 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPNIHGFM_01626 1.3e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPNIHGFM_01627 0.0 asnO 6.3.5.4 E Asparagine synthase
GPNIHGFM_01628 5e-184 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
GPNIHGFM_01629 1.1e-72 V COG4767 Glycopeptide antibiotics resistance protein
GPNIHGFM_01630 2.5e-52 ybaZ 2.1.1.63 L Methyltransferase
GPNIHGFM_01631 1.9e-95 yvbF K Belongs to the GbsR family
GPNIHGFM_01632 7.3e-78 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
GPNIHGFM_01633 1.4e-90 S UPF0316 protein
GPNIHGFM_01634 1.8e-209 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
GPNIHGFM_01635 1.7e-140 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GPNIHGFM_01636 7e-81 CO Thioredoxin-like
GPNIHGFM_01638 3.8e-88 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
GPNIHGFM_01639 1e-100 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
GPNIHGFM_01640 1.2e-85 fur P Belongs to the Fur family
GPNIHGFM_01641 9.6e-14 S Protein of unknown function (DUF4227)
GPNIHGFM_01642 2.2e-165 xerD L recombinase XerD
GPNIHGFM_01643 5e-226 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPNIHGFM_01644 3.5e-228 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
GPNIHGFM_01645 1.8e-69 ohrB O Organic hydroperoxide resistance protein
GPNIHGFM_01646 9.4e-120 yocB J translation release factor activity
GPNIHGFM_01647 4.6e-239 emrB_1 EGP Major facilitator Superfamily
GPNIHGFM_01648 2.1e-20 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
GPNIHGFM_01649 2.4e-51
GPNIHGFM_01650 2.7e-82 yvsG S LexA-binding, inner membrane-associated putative hydrolase
GPNIHGFM_01651 5.2e-131 3.5.1.104 G Polysaccharide deacetylase
GPNIHGFM_01652 5.5e-209 dacF 3.4.16.4 M Belongs to the peptidase S11 family
GPNIHGFM_01653 3.9e-54 spoIIAA T Belongs to the anti-sigma-factor antagonist family
GPNIHGFM_01654 1.4e-72 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
GPNIHGFM_01655 4.8e-137 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNIHGFM_01656 2.2e-79 S Pfam:SpoVA
GPNIHGFM_01657 4.9e-182 spoVAD I Stage V sporulation protein AD
GPNIHGFM_01658 2.5e-56 spoVAEB S Pfam:SpoVA
GPNIHGFM_01659 9.8e-106 spoVAEA S Stage V sporulation protein AE
GPNIHGFM_01660 6.4e-271 spoVAF EG Stage V sporulation protein AF
GPNIHGFM_01661 1.1e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GPNIHGFM_01662 1.4e-80 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPNIHGFM_01663 1.1e-62 tspO T membrane
GPNIHGFM_01664 3.6e-157 ccpC K Transcriptional regulator
GPNIHGFM_01666 6.6e-196 S Psort location CytoplasmicMembrane, score
GPNIHGFM_01667 2e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
GPNIHGFM_01668 1.6e-271 prpD 4.2.1.79 S 2-methylcitrate dehydratase
GPNIHGFM_01669 1.1e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPNIHGFM_01670 3.2e-156 hgd 1.1.1.31, 1.1.1.60 I 3-hydroxyisobutyrate dehydrogenase
GPNIHGFM_01671 2.3e-273 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNIHGFM_01672 4.6e-191 echA9 1.1.1.31, 3.1.2.4, 4.2.1.17 I 3-hydroxyisobutyryl-CoA hydrolase
GPNIHGFM_01673 9.4e-110 ribE 2.5.1.9 H Riboflavin synthase
GPNIHGFM_01674 2.1e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPNIHGFM_01675 7.9e-82 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GPNIHGFM_01676 4.6e-82 ypuF S Domain of unknown function (DUF309)
GPNIHGFM_01677 1.4e-125 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GPNIHGFM_01678 2e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GPNIHGFM_01679 1.2e-103 K Uncharacterized protein conserved in bacteria (DUF2087)
GPNIHGFM_01680 4.3e-294 aldA C Belongs to the aldehyde dehydrogenase family
GPNIHGFM_01681 5e-167 sodA 1.15.1.1 P Superoxide dismutase
GPNIHGFM_01682 4.9e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPNIHGFM_01683 1.5e-305 ubiB S ABC1 family
GPNIHGFM_01684 1.5e-44 S ATP synthase, subunit b
GPNIHGFM_01685 1.9e-121 S membrane
GPNIHGFM_01686 7.1e-45 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPNIHGFM_01687 7.6e-77 spoVAC S stage V sporulation protein AC
GPNIHGFM_01688 5.3e-192 spoVAD I Stage V sporulation protein AD
GPNIHGFM_01689 1.2e-55 spoVAE S stage V sporulation protein
GPNIHGFM_01690 2.4e-209 dacB 3.4.16.4 M Belongs to the peptidase S11 family
GPNIHGFM_01691 4.3e-101 spmA S Spore maturation protein
GPNIHGFM_01692 1.6e-75 spmB S Spore maturation protein
GPNIHGFM_01693 3.7e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPNIHGFM_01694 7.5e-97 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
GPNIHGFM_01695 3.5e-291 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
GPNIHGFM_01696 1.4e-204 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
GPNIHGFM_01697 9e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNIHGFM_01698 0.0 resE 2.7.13.3 T Histidine kinase
GPNIHGFM_01699 7.1e-187 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNIHGFM_01700 7.5e-138 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
GPNIHGFM_01701 1.2e-94 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
GPNIHGFM_01703 3.4e-135 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
GPNIHGFM_01704 2.7e-247 nox 1.6.3.4 P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GPNIHGFM_01705 3.9e-298 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPNIHGFM_01706 3.9e-43 fer C Ferredoxin
GPNIHGFM_01707 3.9e-174 ypbB 5.1.3.1 S protein conserved in bacteria
GPNIHGFM_01708 8.5e-263 recQ 3.6.4.12 L DNA helicase
GPNIHGFM_01709 1e-99 ypbD S metal-dependent membrane protease
GPNIHGFM_01711 2.7e-09 ypbF S Protein of unknown function (DUF2663)
GPNIHGFM_01712 1.3e-51 K Helix-turn-helix XRE-family like proteins
GPNIHGFM_01713 7.2e-37 sinR K Helix-turn-helix XRE-family like proteins
GPNIHGFM_01714 5.1e-226 mgs 2.4.1.337 GT4 M Glycosyl Transferase
GPNIHGFM_01715 5.6e-197 cpoA GT4 M Glycosyl transferases group 1
GPNIHGFM_01716 2.5e-176 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPNIHGFM_01718 1.1e-220 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GPNIHGFM_01719 4.6e-143 ypbG S Calcineurin-like phosphoesterase superfamily domain
GPNIHGFM_01720 1.4e-164 merR K MerR family transcriptional regulator
GPNIHGFM_01721 1.6e-108 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GPNIHGFM_01722 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNIHGFM_01723 5.4e-267 T PhoQ Sensor
GPNIHGFM_01724 1.6e-177
GPNIHGFM_01725 1.6e-238 gdhA 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
GPNIHGFM_01726 9.9e-180 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
GPNIHGFM_01727 3.3e-175 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GPNIHGFM_01728 1.7e-111 prsW S Involved in the degradation of specific anti-sigma factors
GPNIHGFM_01729 6.9e-25
GPNIHGFM_01730 1.8e-206 metB 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
GPNIHGFM_01731 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
GPNIHGFM_01732 0.0 metH 2.1.1.13 E Methionine synthase
GPNIHGFM_01733 2e-163 sleB 3.5.1.28 M Spore cortex-lytic enzyme
GPNIHGFM_01734 8.4e-246 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
GPNIHGFM_01735 5.9e-130 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GPNIHGFM_01736 2.9e-105 plsC 2.3.1.51, 2.7.4.25 I 1-acyl-sn-glycerol-3-phosphate acyltransferase
GPNIHGFM_01737 1.4e-201 rpsA 1.17.7.4 J Ribosomal protein S1
GPNIHGFM_01738 3e-12 yphA
GPNIHGFM_01739 1.2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GPNIHGFM_01740 9e-102 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GPNIHGFM_01741 4.1e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GPNIHGFM_01742 4e-38 S Stage VI sporulation protein F
GPNIHGFM_01744 5.7e-132 yphF
GPNIHGFM_01745 4.4e-280 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GPNIHGFM_01746 8.6e-99 folE 3.5.4.16 H GTP cyclohydrolase
GPNIHGFM_01747 1.6e-35 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
GPNIHGFM_01748 7.7e-58 hepS 2.5.1.30 H heptaprenyl diphosphate synthase
GPNIHGFM_01749 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GPNIHGFM_01750 9.7e-158 ubiA 2.5.1.39 H UbiA prenyltransferase family
GPNIHGFM_01751 2.9e-159 mqnA 1.21.98.1, 4.2.1.151 S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GPNIHGFM_01752 6.9e-181 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPNIHGFM_01753 1.4e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GPNIHGFM_01754 1.2e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
GPNIHGFM_01755 3.1e-220 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPNIHGFM_01756 9.6e-192 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPNIHGFM_01757 4.7e-58 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
GPNIHGFM_01758 3.6e-282 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPNIHGFM_01759 3.2e-181 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPNIHGFM_01760 3.7e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
GPNIHGFM_01761 1.7e-114 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E phosphoribosylanthranilate isomerase activity
GPNIHGFM_01762 1.8e-223 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GPNIHGFM_01763 1.7e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GPNIHGFM_01764 2e-205 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPNIHGFM_01765 3.3e-200 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
GPNIHGFM_01766 1.2e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GPNIHGFM_01767 4.8e-227 S COG0457 FOG TPR repeat
GPNIHGFM_01768 2.6e-97 ypiB S Belongs to the UPF0302 family
GPNIHGFM_01769 3.3e-80 ypiF S Protein of unknown function (DUF2487)
GPNIHGFM_01770 4.8e-90 qcrA C Menaquinol-cytochrome c reductase
GPNIHGFM_01771 7.7e-123 petB C COG1290 Cytochrome b subunit of the bc complex
GPNIHGFM_01772 1.7e-145 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
GPNIHGFM_01773 8.4e-108 ypjA S membrane
GPNIHGFM_01774 1.8e-139 S Sporulation protein YpjB (SpoYpjB)
GPNIHGFM_01775 5.9e-118 yugP S Zn-dependent protease
GPNIHGFM_01776 3.6e-211 tcaB EGP Major facilitator Superfamily
GPNIHGFM_01777 1.1e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
GPNIHGFM_01778 1.4e-201 L Transposase
GPNIHGFM_01779 1.1e-59 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
GPNIHGFM_01780 7.2e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GPNIHGFM_01781 6.5e-75 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
GPNIHGFM_01782 4.2e-81 M Acetyltransferase (GNAT) domain
GPNIHGFM_01783 2.7e-235 rtcB 6.5.1.3 S tRNA-splicing ligase RtcB
GPNIHGFM_01784 1.4e-37
GPNIHGFM_01785 2.6e-71 yjcF S Acetyltransferase (GNAT) domain
GPNIHGFM_01786 2.6e-135 Q Methyltransferase domain
GPNIHGFM_01787 6.1e-51
GPNIHGFM_01788 1.1e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPNIHGFM_01789 2.4e-87 S Protein of unknown function (DUF1706)
GPNIHGFM_01790 2.5e-264 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPNIHGFM_01791 5e-128 yodH Q Methyltransferase
GPNIHGFM_01792 3.3e-139 M 3D domain
GPNIHGFM_01793 4.9e-159 M 3D domain
GPNIHGFM_01794 5.3e-156 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPNIHGFM_01795 1.6e-176 L Transposase
GPNIHGFM_01796 4.4e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
GPNIHGFM_01797 5.4e-147 ysaA S HAD-hyrolase-like
GPNIHGFM_01798 1.2e-101 ykoE S ABC-type cobalt transport system, permease component
GPNIHGFM_01799 5.7e-272 ykoD 3.6.3.24 P ABC transporter
GPNIHGFM_01800 6.3e-140 ykoC P Cobalt transport protein
GPNIHGFM_01801 1.6e-108 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
GPNIHGFM_01802 9.8e-106 yvdD_1 3.2.2.10 S Belongs to the LOG family
GPNIHGFM_01803 7.6e-84 lytE2 M COG1388 FOG LysM repeat
GPNIHGFM_01804 4.6e-227 els S Acetyltransferase
GPNIHGFM_01805 8.5e-102 yvdT K Transcriptional regulator
GPNIHGFM_01806 1.5e-183 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNIHGFM_01807 1.5e-135 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
GPNIHGFM_01808 1.8e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNIHGFM_01809 6.3e-168 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
GPNIHGFM_01810 3.5e-208 mccB 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
GPNIHGFM_01811 0.0 uvrD 3.6.4.12 L DNA helicase
GPNIHGFM_01812 4.5e-169 phnD P Phosphonate ABC transporter
GPNIHGFM_01813 9.1e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GPNIHGFM_01814 2.4e-136 phnE 3.6.1.63 P ABC transporter
GPNIHGFM_01815 6.8e-142 phnE 3.6.1.63 P ABC transporter
GPNIHGFM_01816 3.1e-139 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPNIHGFM_01817 1.1e-242 matE V MatE
GPNIHGFM_01818 7.3e-101 tetR K Bacterial regulatory proteins, tetR family
GPNIHGFM_01819 6.6e-164 3.4.11.5 I Alpha/beta hydrolase family
GPNIHGFM_01820 2.4e-159 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_01821 1.7e-182 dppB EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_01822 1.5e-300 E COG0747 ABC-type dipeptide transport system, periplasmic component
GPNIHGFM_01823 1e-184 appF E Belongs to the ABC transporter superfamily
GPNIHGFM_01824 3.7e-182 dppD P Belongs to the ABC transporter superfamily
GPNIHGFM_01825 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
GPNIHGFM_01826 2.1e-227 S Sulphur transport
GPNIHGFM_01827 3.3e-175 S transport system, periplasmic component
GPNIHGFM_01828 6.7e-171 S Belongs to the binding-protein-dependent transport system permease family
GPNIHGFM_01829 1.3e-137 S transport system, ATPase component
GPNIHGFM_01830 1.2e-180
GPNIHGFM_01831 6.4e-196 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GPNIHGFM_01832 5.4e-136 cysW P COG4208 ABC-type sulfate transport system, permease component
GPNIHGFM_01833 1.2e-130 cysT O COG0555 ABC-type sulfate transport system, permease component
GPNIHGFM_01834 2.2e-193 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
GPNIHGFM_01835 1.7e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPNIHGFM_01836 8.2e-296 T COG0642 Signal transduction histidine kinase
GPNIHGFM_01837 7.1e-78 dld 1.1.1.303, 1.1.1.4, 1.1.2.4, 1.1.3.15 C Glycolate oxidase subunit
GPNIHGFM_01838 5.9e-169 dld 1.1.1.303, 1.1.1.4, 1.1.2.4, 1.1.3.15 C Glycolate oxidase subunit
GPNIHGFM_01839 3.8e-155 yocS S -transporter
GPNIHGFM_01840 6.4e-238 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GPNIHGFM_01841 5.9e-155 nhaR K LysR substrate binding domain
GPNIHGFM_01842 2e-294 E COG0747 ABC-type dipeptide transport system, periplasmic component
GPNIHGFM_01843 1.3e-204 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
GPNIHGFM_01844 1.9e-63 K Helix-turn-helix XRE-family like proteins
GPNIHGFM_01845 2e-94 2.3.1.128 J Acetyltransferase (GNAT) domain
GPNIHGFM_01846 6.3e-151 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01847 6.4e-168 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01848 1.9e-266 G Bacterial extracellular solute-binding protein
GPNIHGFM_01849 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
GPNIHGFM_01850 8.7e-170 yisR1 K AraC-like ligand binding domain
GPNIHGFM_01851 7.5e-121 mutF V ABC transporter, ATP-binding protein
GPNIHGFM_01852 9.9e-119 spaE S ABC-2 family transporter protein
GPNIHGFM_01853 2.5e-122 mutG S ABC-2 family transporter protein
GPNIHGFM_01854 9.3e-121 K Transcriptional regulatory protein, C terminal
GPNIHGFM_01855 8.5e-249 T His Kinase A (phosphoacceptor) domain
GPNIHGFM_01856 1.7e-72 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPNIHGFM_01857 1.6e-73 lrpC K helix_turn_helix ASNC type
GPNIHGFM_01858 5.7e-104 argO S Lysine exporter protein LysE YggA
GPNIHGFM_01859 2.2e-273 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNIHGFM_01860 9.8e-94 ykkA S Protein of unknown function (DUF664)
GPNIHGFM_01861 2.9e-75 yuxK S protein conserved in bacteria
GPNIHGFM_01862 1.1e-44
GPNIHGFM_01863 1.4e-63 M nuclease activity
GPNIHGFM_01864 3.5e-147 yjqC P Catalase
GPNIHGFM_01865 1.5e-107 E Lysine exporter protein LysE YggA
GPNIHGFM_01866 1.6e-244 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
GPNIHGFM_01867 4.6e-117 yhcQ M Spore coat protein
GPNIHGFM_01869 2.7e-174 eutC 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
GPNIHGFM_01870 1.8e-173 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
GPNIHGFM_01871 2.6e-209 mntH P H( )-stimulated, divalent metal cation uptake system
GPNIHGFM_01872 2.3e-116 S HTH domain
GPNIHGFM_01873 1.1e-188 speB 3.5.3.11 E Arginase family
GPNIHGFM_01874 5.7e-129 T Transcriptional regulator
GPNIHGFM_01875 1e-204 T PhoQ Sensor
GPNIHGFM_01876 1.4e-164 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
GPNIHGFM_01877 5.6e-121 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
GPNIHGFM_01878 1e-108 ydfE S Flavin reductase like domain
GPNIHGFM_01879 8.6e-142 C KR domain
GPNIHGFM_01880 6.9e-54 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
GPNIHGFM_01881 6e-172 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
GPNIHGFM_01882 2.5e-98 srlA G PTS system enzyme II sorbitol-specific factor
GPNIHGFM_01883 3.1e-75 gutM K Glucitol operon activator
GPNIHGFM_01884 1.7e-171 sorC K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GPNIHGFM_01885 1.6e-274 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
GPNIHGFM_01886 9.6e-283 uxaA 4.2.1.7 G Altronate
GPNIHGFM_01887 8.6e-248 yteT S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_01888 1.7e-120 S Integral membrane protein
GPNIHGFM_01889 9.5e-78 G carbohydrate transport
GPNIHGFM_01890 8.3e-223 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
GPNIHGFM_01891 2.2e-311 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
GPNIHGFM_01892 1.5e-74 E Abhydrolase family
GPNIHGFM_01893 1.2e-62 E Abhydrolase family
GPNIHGFM_01894 2.7e-144 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01895 1.3e-179 G COG4209 ABC-type polysaccharide transport system, permease component
GPNIHGFM_01896 1.7e-295 G ABC transporter substrate-binding protein
GPNIHGFM_01897 0.0 K Transcriptional regulator
GPNIHGFM_01898 6.2e-157 3.2.2.21 K AraC-like ligand binding domain
GPNIHGFM_01899 2.5e-189 pelE 3.4.11.10, 3.4.11.6, 4.2.2.2 M Pectic acid lyase
GPNIHGFM_01900 1.9e-104 J Acetyltransferase (GNAT) domain
GPNIHGFM_01901 2.1e-129 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
GPNIHGFM_01902 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
GPNIHGFM_01903 0.0 lplA7 G Bacterial extracellular solute-binding protein
GPNIHGFM_01904 3.7e-168 lplC1 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01905 1.1e-173 lplB P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01906 2.6e-272 araC7 T helix_turn_helix, arabinose operon control protein
GPNIHGFM_01907 0.0 2.7.13.3 T Histidine kinase
GPNIHGFM_01908 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
GPNIHGFM_01909 1.8e-210 glcP G Major Facilitator Superfamily
GPNIHGFM_01910 9.8e-183 xylR3 2.7.1.2 GK ROK family
GPNIHGFM_01911 1.8e-273 M1-1044 S Belongs to the UPF0061 (SELO) family
GPNIHGFM_01912 3.9e-73 S DinB superfamily
GPNIHGFM_01913 1.1e-164 Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
GPNIHGFM_01914 5.8e-137 ygaJ E Belongs to the peptidase S51 family
GPNIHGFM_01915 3.5e-162 S Alpha beta hydrolase
GPNIHGFM_01917 2.7e-73 dcd 3.5.4.13 F 2'-deoxycytidine 5'-triphosphate deaminase (DCD)
GPNIHGFM_01918 9.8e-151 P COG0370 Fe2 transport system protein B
GPNIHGFM_01919 8.1e-166 yjiA S Cobalamin biosynthesis protein CobW
GPNIHGFM_01920 5.8e-183 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
GPNIHGFM_01921 1.5e-222 adcA P Zinc-uptake complex component A periplasmic
GPNIHGFM_01922 2.9e-128 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GPNIHGFM_01923 1.9e-123 adcB P ABC 3 transport family
GPNIHGFM_01924 9.8e-264 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNIHGFM_01925 4.5e-166 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
GPNIHGFM_01926 9.9e-163 MA20_14845 4.2.1.141 S Fumarylacetoacetate (FAA) hydrolase family
GPNIHGFM_01927 7.5e-138 K helix_turn_helix isocitrate lyase regulation
GPNIHGFM_01928 0.0 yjhG 4.2.1.82 EG Dehydratase family
GPNIHGFM_01929 4.8e-239 yjhF EG COG2610 H gluconate symporter and related permeases
GPNIHGFM_01930 2.3e-31 K MerR family transcriptional regulator
GPNIHGFM_01931 4.9e-134 IQ Enoyl-(Acyl carrier protein) reductase
GPNIHGFM_01932 3.8e-97
GPNIHGFM_01933 7.3e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPNIHGFM_01934 1.1e-77 fld C Flavodoxin
GPNIHGFM_01935 1.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GPNIHGFM_01936 6.6e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPNIHGFM_01937 2.7e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GPNIHGFM_01938 1.8e-44 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPNIHGFM_01939 2e-88 yizA S DinB family
GPNIHGFM_01940 1.5e-172
GPNIHGFM_01942 9.8e-156 yufQ S Belongs to the binding-protein-dependent transport system permease family
GPNIHGFM_01943 1.3e-188 yufP S Belongs to the binding-protein-dependent transport system permease family
GPNIHGFM_01944 2.7e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
GPNIHGFM_01945 3.2e-203 bmpA S ABC-type transport system, periplasmic component surface lipoprotein
GPNIHGFM_01946 5.8e-219 camS S COG4851 Protein involved in sex pheromone biosynthesis
GPNIHGFM_01947 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPNIHGFM_01948 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GPNIHGFM_01949 6.8e-122 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GPNIHGFM_01951 5.7e-152 fhuC 3.6.3.34 HP ABC transporter
GPNIHGFM_01952 1.7e-169 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNIHGFM_01953 9.4e-176 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNIHGFM_01955 2e-27 mepA V MATE efflux family protein
GPNIHGFM_01956 4.8e-165 lacX G Aldose 1-epimerase
GPNIHGFM_01957 0.0 acyII 3.5.1.11, 3.5.1.97 S Penicillin amidase
GPNIHGFM_01958 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GPNIHGFM_01959 1.2e-49 yerC S protein conserved in bacteria
GPNIHGFM_01960 0.0 3.5.4.2 F adenine deaminase
GPNIHGFM_01961 1.2e-194 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
GPNIHGFM_01962 1.2e-155 opuAC E glycine betaine
GPNIHGFM_01963 5.6e-147 proW P glycine betaine
GPNIHGFM_01964 4.7e-219 gbuA 3.6.3.32 E glycine betaine
GPNIHGFM_01965 2.5e-95 K Belongs to the GbsR family
GPNIHGFM_01966 3.2e-22
GPNIHGFM_01967 1.9e-167 K Putative sugar-binding domain
GPNIHGFM_01968 4.2e-59 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
GPNIHGFM_01969 1e-179 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
GPNIHGFM_01970 5.6e-89 srlA G PTS system enzyme II sorbitol-specific factor
GPNIHGFM_01971 6.4e-67 K Glucitol operon activator protein (GutM)
GPNIHGFM_01972 9e-234 thrA E SAF
GPNIHGFM_01973 2.3e-35 ptsH G PTS HPr component phosphorylation site
GPNIHGFM_01974 1.2e-115
GPNIHGFM_01975 5.9e-92 S VanZ like family
GPNIHGFM_01976 9.6e-77 yybA 2.3.1.57 K transcriptional
GPNIHGFM_01977 3.9e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNIHGFM_01978 1.5e-172 ssuA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GPNIHGFM_01979 5.6e-104 ssuC P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01980 1.1e-155 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
GPNIHGFM_01981 2e-252 glcF C Glycolate oxidase
GPNIHGFM_01982 7.7e-258 glcD 1.1.3.15 C Glycolate oxidase subunit
GPNIHGFM_01983 2.5e-203 ysfB KT regulator
GPNIHGFM_01984 5.9e-233 yxiO S COG2270 Permeases of the major facilitator superfamily
GPNIHGFM_01985 5.9e-141 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GPNIHGFM_01986 7.5e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
GPNIHGFM_01987 3.5e-10 Q Thioesterase superfamily
GPNIHGFM_01988 6.4e-12 chpR T Transcriptional regulator antitoxin, MazE
GPNIHGFM_01989 2.4e-40 mazF T PemK-like, MazF-like toxin of type II toxin-antitoxin system
GPNIHGFM_01990 1.5e-25 topA2 5.99.1.2 L Topoisomerase IA
GPNIHGFM_01991 5e-298 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GPNIHGFM_01992 4.9e-09
GPNIHGFM_01993 7.6e-146
GPNIHGFM_01994 3.1e-206 ysh1 J Metallo-beta-lactamase superfamily
GPNIHGFM_01995 1.6e-291 ftpA P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_01996 1.2e-188 ftpB P Bacterial extracellular solute-binding protein
GPNIHGFM_01997 6.2e-182 phnT 3.6.3.30 P ABC transporter
GPNIHGFM_01998 2.6e-158 rbcR1 K Transcriptional regulator
GPNIHGFM_01999 1.1e-54 S Family of unknown function (DUF5367)
GPNIHGFM_02000 2.1e-100 K Bacterial regulatory proteins, tetR family
GPNIHGFM_02002 1.4e-162 EG EamA-like transporter family
GPNIHGFM_02003 5.7e-234 ywoF P Right handed beta helix region
GPNIHGFM_02004 6.3e-96 mutT 3.6.1.13, 3.6.1.55 L nUDIX hydrolase
GPNIHGFM_02005 1.6e-63 S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNIHGFM_02006 3.4e-255 G Bacterial extracellular solute-binding protein
GPNIHGFM_02007 1.3e-146 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02008 2.8e-97 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02009 1.7e-22 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02010 1.1e-217 3.2.1.180 GH88 O Glycosyl Hydrolase Family 88
GPNIHGFM_02011 1.8e-164 3.2.2.21 K AraC-like ligand binding domain
GPNIHGFM_02012 1.7e-223 S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_02013 3e-209 S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_02014 1.7e-98 3.2.2.21 K AraC-like ligand binding domain
GPNIHGFM_02015 2.9e-142 G Xylose isomerase-like TIM barrel
GPNIHGFM_02016 7.3e-155 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02017 1e-170 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02018 1.4e-253 G Bacterial extracellular solute-binding protein
GPNIHGFM_02019 1.2e-210 S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_02020 8e-137 G Xylose isomerase-like TIM barrel
GPNIHGFM_02021 2.8e-168 3.2.2.21 K Cupin domain
GPNIHGFM_02022 1.9e-189 S Oxidoreductase family, NAD-binding Rossmann fold
GPNIHGFM_02023 4.4e-59 S Protein of unknown function, DUF393
GPNIHGFM_02024 2.1e-144 yfhB 5.3.3.17 S PhzF family
GPNIHGFM_02025 2.6e-106 V Beta-lactamase
GPNIHGFM_02026 1.3e-88 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GPNIHGFM_02027 5.6e-305 2.6.1.52 E Aminotransferase class-V
GPNIHGFM_02028 0.0 ltaS 2.7.8.20 M Sulfatase
GPNIHGFM_02029 1.1e-65 E lactoylglutathione lyase activity
GPNIHGFM_02030 1.4e-150 3.5.1.28 M COG3103 SH3 domain protein
GPNIHGFM_02031 4.3e-110 K LysR substrate binding domain
GPNIHGFM_02032 9.1e-122 pkn1 1.8.3.7 S Sulfatase-modifying factor enzyme 1
GPNIHGFM_02033 5.7e-103 5.1.3.9 G Putative N-acetylmannosamine-6-phosphate epimerase
GPNIHGFM_02034 8.3e-47 2.7.1.201 G PTS system, glucose subfamily, IIA
GPNIHGFM_02035 8.7e-206 atsG P Type I phosphodiesterase / nucleotide pyrophosphatase
GPNIHGFM_02036 3e-218 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
GPNIHGFM_02037 7.3e-87 K Regulates the succiny-lCoA synthetase operon
GPNIHGFM_02038 5.6e-80 S Sulfite exporter TauE/SafE
GPNIHGFM_02039 1.6e-155 htpX O Belongs to the peptidase M48B family
GPNIHGFM_02040 6e-24 mcbG S Pentapeptide repeats (9 copies)
GPNIHGFM_02041 4.9e-148 araQ P PFAM binding-protein-dependent transport systems inner membrane component
GPNIHGFM_02042 2.4e-159 lacF G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02043 1.1e-239 araN G ABC transporter substrate-binding protein
GPNIHGFM_02044 3.9e-48 S Branched-chain amino acid transport protein (AzlD)
GPNIHGFM_02045 2.5e-116 azlC E AzlC protein
GPNIHGFM_02046 5.2e-96 ydcN K Helix-turn-helix XRE-family like proteins
GPNIHGFM_02047 1.8e-87 M FR47-like protein
GPNIHGFM_02049 2.9e-35 S membrane
GPNIHGFM_02050 7e-90 S Peptidase M50
GPNIHGFM_02051 8.3e-235 hisS 6.1.1.21 J histidyl-tRNA synthetase
GPNIHGFM_02052 2.4e-113 ypgQ S phosphohydrolase
GPNIHGFM_02053 7.6e-26
GPNIHGFM_02054 1.2e-272 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
GPNIHGFM_02055 2.9e-204 S Protein of unknown function (DUF917)
GPNIHGFM_02056 4e-213 codB_1 F cytosine purines uracil thiamine allantoin
GPNIHGFM_02057 6.6e-102 K Bacterial regulatory proteins, tetR family
GPNIHGFM_02058 2.1e-135 K acetyltransferase
GPNIHGFM_02059 9.4e-81 S Stage II sporulation protein P (SpoIIP)
GPNIHGFM_02060 9.3e-63 KLT Protein kinase domain
GPNIHGFM_02061 1.2e-83 KLT Protein kinase domain
GPNIHGFM_02062 1.4e-56 FG HIT domain
GPNIHGFM_02063 1.2e-164 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPNIHGFM_02064 3.7e-88
GPNIHGFM_02066 4.1e-178 S COG1073 Hydrolases of the alpha beta superfamily
GPNIHGFM_02067 1.6e-233 S protein conserved in bacteria
GPNIHGFM_02068 4.3e-250 3.5.4.28, 3.5.4.31 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
GPNIHGFM_02069 6.4e-219 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GPNIHGFM_02070 4.4e-239 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
GPNIHGFM_02071 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GPNIHGFM_02072 8.9e-281 T COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
GPNIHGFM_02073 2.1e-214 G Transmembrane secretion effector
GPNIHGFM_02074 1e-183 desK 2.7.13.3 T Histidine kinase
GPNIHGFM_02075 1.2e-103 K helix_turn_helix, Lux Regulon
GPNIHGFM_02076 1.3e-111
GPNIHGFM_02077 1.5e-152 licT K antiterminator
GPNIHGFM_02078 6.5e-268 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
GPNIHGFM_02079 9.1e-175 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
GPNIHGFM_02080 3.6e-81 M Protein of unknown function (DUF1541)
GPNIHGFM_02081 4e-53
GPNIHGFM_02082 2.5e-292 expZ S ABC transporter
GPNIHGFM_02083 7.8e-210 gatD 1.1.1.14 C Alcohol dehydrogenase GroES-like domain
GPNIHGFM_02084 7.3e-21
GPNIHGFM_02085 1.3e-193 gutB 1.1.1.1, 1.1.1.14 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GPNIHGFM_02086 9.4e-215 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
GPNIHGFM_02087 4.8e-42 gatB_1 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
GPNIHGFM_02088 1.2e-74 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GPNIHGFM_02089 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
GPNIHGFM_02090 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
GPNIHGFM_02091 2.9e-185
GPNIHGFM_02092 1.7e-103 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
GPNIHGFM_02093 1.4e-175 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
GPNIHGFM_02094 2.6e-102 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GPNIHGFM_02095 1.7e-88 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
GPNIHGFM_02096 2.8e-198 MA20_17100 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
GPNIHGFM_02097 3e-84 G Tripartite ATP-independent periplasmic transporters, DctQ component
GPNIHGFM_02098 7.9e-164 dctP_1 G Bacterial extracellular solute-binding protein, family 7
GPNIHGFM_02099 5.6e-178 kdgR K transcriptional
GPNIHGFM_02100 4.5e-52 K Transcriptional regulator PadR-like family
GPNIHGFM_02101 7.9e-73
GPNIHGFM_02102 2.2e-73
GPNIHGFM_02103 5.2e-198 frvX 3.2.1.4 GH5,GH9 G M42 glutamyl aminopeptidase
GPNIHGFM_02104 4.1e-41 S Membrane
GPNIHGFM_02105 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
GPNIHGFM_02106 7.7e-165 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GPNIHGFM_02107 1.9e-144 tagG GM Transport permease protein
GPNIHGFM_02108 1.3e-137 S GNAT acetyltransferase
GPNIHGFM_02109 0.0 3.6.3.8 P COG0474 Cation transport ATPase
GPNIHGFM_02110 3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
GPNIHGFM_02112 5.1e-300 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
GPNIHGFM_02113 1.5e-130 modA P COG0725 ABC-type molybdate transport system, periplasmic component
GPNIHGFM_02114 9.7e-110 modB P COG4149 ABC-type molybdate transport system, permease component
GPNIHGFM_02115 7.2e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNIHGFM_02116 8.9e-182 vraS 2.7.13.3 T Histidine kinase
GPNIHGFM_02117 5.7e-124 yvqF S Cell wall-active antibiotics response 4TMS YvqF
GPNIHGFM_02118 2.9e-103
GPNIHGFM_02120 8.5e-113 4.4.1.3, 5.3.1.15 S Cupin
GPNIHGFM_02121 0.0 DSE4 M glycoside hydrolase family 81
GPNIHGFM_02122 2.7e-191 purR11 K helix_turn _helix lactose operon repressor
GPNIHGFM_02123 1.4e-145 P PFAM binding-protein-dependent transport systems inner membrane component
GPNIHGFM_02124 3.3e-156 P PFAM binding-protein-dependent transport systems inner membrane component
GPNIHGFM_02125 1.5e-199 cebE G PFAM extracellular solute-binding protein family 1
GPNIHGFM_02126 6.6e-117 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
GPNIHGFM_02127 8.1e-290 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPNIHGFM_02128 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPNIHGFM_02129 8.6e-58
GPNIHGFM_02131 1.7e-145 ykrA S hydrolases of the HAD superfamily
GPNIHGFM_02132 1.9e-29
GPNIHGFM_02133 9.9e-46 csoR S transcriptional
GPNIHGFM_02134 1.1e-27 copP P Heavy-metal-associated domain
GPNIHGFM_02135 1.4e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
GPNIHGFM_02137 1.5e-191 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
GPNIHGFM_02138 1.1e-215 E Peptidase family M28
GPNIHGFM_02139 5.3e-105 GM NmrA-like family
GPNIHGFM_02140 3.9e-177 ytvI S AI-2E family transporter
GPNIHGFM_02141 5.3e-80 copC S CopC domain
GPNIHGFM_02143 4.7e-194 yhdY M Mechanosensitive ion channel
GPNIHGFM_02144 2e-183 T Metal dependent phosphohydrolases with conserved 'HD' motif.
GPNIHGFM_02145 1.5e-145 S Membrane transport protein
GPNIHGFM_02146 1.3e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GPNIHGFM_02147 2.2e-221 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
GPNIHGFM_02148 1.1e-211 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GPNIHGFM_02149 2.4e-37 ykuS S Belongs to the UPF0180 family
GPNIHGFM_02150 7.9e-127 ykuT M Mechanosensitive ion channel
GPNIHGFM_02151 4.7e-102 ykuU O Alkyl hydroperoxide reductase
GPNIHGFM_02152 4.1e-83 ykuV CO thiol-disulfide
GPNIHGFM_02153 1.1e-113 ktrA P COG0569 K transport systems, NAD-binding component
GPNIHGFM_02154 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPNIHGFM_02155 9.1e-30 ykzG S Belongs to the UPF0356 family
GPNIHGFM_02156 3.7e-99 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPNIHGFM_02158 8.1e-69 recN L Putative cell-wall binding lipoprotein
GPNIHGFM_02159 1.1e-201 bkdA1 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GPNIHGFM_02160 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GPNIHGFM_02161 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPNIHGFM_02162 2.2e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GPNIHGFM_02163 2.8e-185 oppD P Belongs to the ABC transporter superfamily
GPNIHGFM_02164 1.2e-185 E Belongs to the ABC transporter superfamily
GPNIHGFM_02165 0.0 appA_2 E COG0747 ABC-type dipeptide transport system, periplasmic component
GPNIHGFM_02166 6.8e-173 P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_02167 2.3e-162 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_02168 8.5e-66 CO cell redox homeostasis
GPNIHGFM_02169 6.6e-277 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
GPNIHGFM_02170 1.4e-121 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
GPNIHGFM_02171 1.4e-122 legA 3.5.1.2 O Peptidase family M48
GPNIHGFM_02172 4.6e-277 speA 4.1.1.19 E Arginine
GPNIHGFM_02173 1.3e-38 yktA S Belongs to the UPF0223 family
GPNIHGFM_02174 2.3e-113 yktB S Belongs to the UPF0637 family
GPNIHGFM_02175 9.5e-152 suhB 3.1.3.25 G Inositol monophosphatase
GPNIHGFM_02176 2.3e-162 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
GPNIHGFM_02177 3.8e-11 S Family of unknown function (DUF5325)
GPNIHGFM_02178 0.0 typA T GTP-binding protein TypA
GPNIHGFM_02179 1.9e-50 ylaH S YlaH-like protein
GPNIHGFM_02180 3.2e-32 ylaI S protein conserved in bacteria
GPNIHGFM_02181 3.9e-251 phoH T ATPase related to phosphate starvation-inducible protein PhoH
GPNIHGFM_02182 1.6e-91 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GPNIHGFM_02183 9e-41 ylaN S Belongs to the UPF0358 family
GPNIHGFM_02184 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GPNIHGFM_02185 5.9e-158 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
GPNIHGFM_02186 2.7e-199 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
GPNIHGFM_02187 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPNIHGFM_02188 5.7e-104 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
GPNIHGFM_02189 1.8e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
GPNIHGFM_02190 5.7e-92 yozB S membrane
GPNIHGFM_02191 6.7e-84
GPNIHGFM_02192 6.1e-63 ylbA S YugN-like family
GPNIHGFM_02193 7.3e-190 ylbC S protein with SCP PR1 domains
GPNIHGFM_02194 6.6e-84 yiiD Q protein, possibly involved in aromatic compounds catabolism
GPNIHGFM_02195 1.3e-70 ylbD S Putative coat protein
GPNIHGFM_02196 1.2e-31 ylbE S YlbE-like protein
GPNIHGFM_02197 1.5e-138 rimK1 HJ Prokaryotic glutathione synthetase, ATP-grasp domain
GPNIHGFM_02198 2.2e-57 ylbF S Belongs to the UPF0342 family
GPNIHGFM_02199 1.1e-46 ylbG S UPF0298 protein
GPNIHGFM_02200 5.9e-64 S Methylthioribose kinase
GPNIHGFM_02201 6e-97 rsmD 2.1.1.171 L Methyltransferase
GPNIHGFM_02202 2.8e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPNIHGFM_02203 2.6e-214 ylbJ S Sporulation integral membrane protein YlbJ
GPNIHGFM_02204 5.8e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
GPNIHGFM_02205 3.9e-190 ylbL T Belongs to the peptidase S16 family
GPNIHGFM_02206 1.3e-221 ylbM S Belongs to the UPF0348 family
GPNIHGFM_02207 6.4e-93 yceD S metal-binding, possibly nucleic acid-binding protein
GPNIHGFM_02208 1.3e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GPNIHGFM_02209 3.6e-62 S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
GPNIHGFM_02210 5.2e-92 ylbP K n-acetyltransferase
GPNIHGFM_02211 2.9e-146 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPNIHGFM_02212 1e-10 S Protein of unknown function (DUF3397)
GPNIHGFM_02213 9.7e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GPNIHGFM_02214 2.6e-79 mraZ K Belongs to the MraZ family
GPNIHGFM_02215 4.8e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GPNIHGFM_02216 6e-47 ftsL D cell division protein FtsL
GPNIHGFM_02217 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
GPNIHGFM_02219 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
GPNIHGFM_02220 1.8e-270 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPNIHGFM_02221 8e-244 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GPNIHGFM_02222 9.3e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPNIHGFM_02223 3.3e-242 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPNIHGFM_02224 5.2e-185 spoVE D Belongs to the SEDS family
GPNIHGFM_02225 1.8e-120 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GPNIHGFM_02227 7.6e-220 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GPNIHGFM_02228 9e-185 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPNIHGFM_02229 1e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
GPNIHGFM_02230 1.1e-124 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNIHGFM_02231 6.2e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNIHGFM_02232 1.7e-45 ylmC S sporulation protein
GPNIHGFM_02233 3.7e-143 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
GPNIHGFM_02234 2.2e-117 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPNIHGFM_02235 4.9e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GPNIHGFM_02236 2e-43 yggT S membrane
GPNIHGFM_02237 9e-136 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
GPNIHGFM_02238 1.8e-63 divIVA D Cell division initiation protein
GPNIHGFM_02239 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPNIHGFM_02240 2e-109 dksA T COG1734 DnaK suppressor protein
GPNIHGFM_02241 1.1e-72 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPNIHGFM_02242 1.9e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPNIHGFM_02243 2.6e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GPNIHGFM_02244 1.3e-227 pyrP F Xanthine uracil
GPNIHGFM_02245 8.7e-162 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GPNIHGFM_02246 3e-240 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GPNIHGFM_02247 4.3e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GPNIHGFM_02248 0.0 carB 6.3.5.5 F Belongs to the CarB family
GPNIHGFM_02249 1.2e-140 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GPNIHGFM_02250 5.8e-166 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GPNIHGFM_02251 1.2e-121 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GPNIHGFM_02252 7.8e-109 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPNIHGFM_02253 1.9e-113 Q ubiE/COQ5 methyltransferase family
GPNIHGFM_02255 0.0 yfhO S Bacterial membrane protein YfhO
GPNIHGFM_02256 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
GPNIHGFM_02257 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
GPNIHGFM_02258 3.5e-39 ylzA S Belongs to the UPF0296 family
GPNIHGFM_02259 6.9e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GPNIHGFM_02260 1e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GPNIHGFM_02261 3.1e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPNIHGFM_02262 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPNIHGFM_02263 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPNIHGFM_02264 6.7e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPNIHGFM_02265 2.9e-131 stp 3.1.3.16 T phosphatase
GPNIHGFM_02266 0.0 KLT serine threonine protein kinase
GPNIHGFM_02267 1.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GPNIHGFM_02268 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GPNIHGFM_02269 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GPNIHGFM_02270 1.5e-59 asp S protein conserved in bacteria
GPNIHGFM_02271 5.7e-300 yloV S kinase related to dihydroxyacetone kinase
GPNIHGFM_02272 5.2e-148 degV3 S protein conserved in bacteria
GPNIHGFM_02273 4.6e-120 sdaAB 4.3.1.17 E L-serine dehydratase
GPNIHGFM_02274 7.7e-147 sdaAA 4.3.1.17 E L-serine dehydratase
GPNIHGFM_02275 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPNIHGFM_02276 9.6e-98 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
GPNIHGFM_02277 1.1e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GPNIHGFM_02278 7.2e-167 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GPNIHGFM_02279 2.2e-126 IQ reductase
GPNIHGFM_02280 5.4e-31 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPNIHGFM_02281 4.4e-138 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GPNIHGFM_02282 1.5e-09 yfkK S Belongs to the UPF0435 family
GPNIHGFM_02283 0.0 smc D Required for chromosome condensation and partitioning
GPNIHGFM_02284 2.6e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPNIHGFM_02285 3e-51 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GPNIHGFM_02286 1.6e-244 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPNIHGFM_02287 5.5e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GPNIHGFM_02288 2.5e-33 ylqC S Belongs to the UPF0109 family
GPNIHGFM_02289 1.5e-68 ylqD S YlqD protein
GPNIHGFM_02290 4.2e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPNIHGFM_02291 2.2e-131 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GPNIHGFM_02292 0.0 argS 6.1.1.19 J Arginyl tRNA synthetase N terminal dom
GPNIHGFM_02293 2.5e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GPNIHGFM_02294 6.7e-154 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPNIHGFM_02295 1.4e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GPNIHGFM_02296 4.7e-112 cpsE M Bacterial sugar transferase
GPNIHGFM_02297 3.1e-83 wzx S Membrane protein involved in the export of O-antigen and teichoic acid
GPNIHGFM_02298 1.1e-75 1.13.11.79 C Nitroreductase family
GPNIHGFM_02299 1.9e-73 S PFAM Polysaccharide pyruvyl transferase
GPNIHGFM_02300 4.1e-76 M Glycosyl transferases group 1
GPNIHGFM_02301 7.5e-75 M Glycosyl transferases group 1
GPNIHGFM_02302 7.4e-91 cps4F 2.4.1.306 GT4 M Glycosyl transferase 4-like
GPNIHGFM_02303 6.7e-67
GPNIHGFM_02304 1.1e-77 G Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GPNIHGFM_02305 2.5e-216 manC 2.7.7.13, 5.3.1.8 G mannose-1-phosphate guanylyltransferase
GPNIHGFM_02306 7e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPNIHGFM_02307 2.2e-24 S Domain of unknown function (DUF3784)
GPNIHGFM_02309 6e-126 lacR K AraC-type transcriptional regulator N-terminus
GPNIHGFM_02310 9.9e-49 S Agrobacterium tumefaciens protein Atu4866
GPNIHGFM_02311 4.3e-111 S Enoyl-(Acyl carrier protein) reductase
GPNIHGFM_02313 4.2e-101 1.6.5.2 S NADPH-dependent FMN reductase
GPNIHGFM_02314 1.4e-65 ytcD5 K Transcriptional regulator
GPNIHGFM_02315 1.8e-115 L COG2801 Transposase and inactivated derivatives
GPNIHGFM_02316 6.5e-31 L Transposase
GPNIHGFM_02319 5.7e-104 S LXG domain of WXG superfamily
GPNIHGFM_02320 7.1e-11
GPNIHGFM_02325 3.3e-262 ydbT S Bacterial PH domain
GPNIHGFM_02326 7.2e-86 S Bacterial PH domain
GPNIHGFM_02327 6.2e-112 S CAAX protease self-immunity
GPNIHGFM_02328 3.5e-09 M Exporter of polyketide antibiotics
GPNIHGFM_02329 2.1e-249 celF 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GPNIHGFM_02330 1.7e-45
GPNIHGFM_02331 1.9e-223 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPNIHGFM_02332 2.3e-50 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
GPNIHGFM_02333 2.8e-49 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
GPNIHGFM_02334 1.1e-208 ybhE S Bacterial protein of unknown function (DUF871)
GPNIHGFM_02335 2.2e-152 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
GPNIHGFM_02336 1.4e-164 K Transcriptional regulator
GPNIHGFM_02338 1.6e-291 E Bacterial extracellular solute-binding proteins, family 5 Middle
GPNIHGFM_02339 1.5e-156 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02340 5.9e-166 EP N-terminal TM domain of oligopeptide transport permease C
GPNIHGFM_02341 5.5e-186 oppD P Belongs to the ABC transporter superfamily
GPNIHGFM_02342 3.4e-194 E Belongs to the ABC transporter superfamily
GPNIHGFM_02343 9.6e-225 E Peptidase family M28
GPNIHGFM_02344 1.2e-250 P Sodium:sulfate symporter transmembrane region
GPNIHGFM_02345 1.5e-219 3.5.1.47 S Peptidase dimerisation domain
GPNIHGFM_02346 6.6e-226 3.5.1.47 S Peptidase dimerisation domain
GPNIHGFM_02347 2.3e-87
GPNIHGFM_02349 5.5e-189 P Bacterial extracellular solute-binding protein
GPNIHGFM_02350 6.3e-199 fbpC2 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GPNIHGFM_02351 6.2e-291 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02352 5.4e-303 2.7.13.3 T Histidine kinase
GPNIHGFM_02353 8.6e-139 T helix_turn_helix, arabinose operon control protein
GPNIHGFM_02354 8e-202 S response regulator aspartate phosphatase
GPNIHGFM_02355 5.5e-127 puuD 4.1.3.27 S Peptidase C26
GPNIHGFM_02356 6.3e-149 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPNIHGFM_02357 1.4e-33
GPNIHGFM_02358 3.3e-37
GPNIHGFM_02359 1.5e-152 S response regulator aspartate phosphatase
GPNIHGFM_02360 1.3e-207 S Protein of unknown function (DUF418)
GPNIHGFM_02361 2e-14
GPNIHGFM_02362 2.6e-28 K Bacterial regulatory proteins, tetR family
GPNIHGFM_02363 6.1e-165 S Belongs to the pirin family
GPNIHGFM_02364 6.8e-59 hxlR K HxlR-like helix-turn-helix
GPNIHGFM_02365 3.4e-247 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
GPNIHGFM_02366 8.3e-170 aadK G Streptomycin adenylyltransferase
GPNIHGFM_02367 2.8e-173 cat P Catalase
GPNIHGFM_02368 2.8e-41 S Protein of unknown function (DUF2642)
GPNIHGFM_02370 2.2e-204 S response regulator aspartate phosphatase
GPNIHGFM_02371 3.3e-130 K Transcriptional regulator
GPNIHGFM_02372 1.1e-189 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
GPNIHGFM_02373 8.3e-85 dctQ1 G Tripartite ATP-independent periplasmic transporters, DctQ component
GPNIHGFM_02374 4.3e-218 siaT_2 G Tripartite ATP-independent periplasmic transporter, DctM component
GPNIHGFM_02375 3e-139 IQ Enoyl-(Acyl carrier protein) reductase
GPNIHGFM_02376 1.3e-92 S DNA-binding protein with PD1-like DNA-binding motif
GPNIHGFM_02377 3.7e-287 MA20_41335 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPNIHGFM_02378 4.2e-206 2.3.1.16, 2.3.1.9 I Thiolase, C-terminal domain
GPNIHGFM_02379 4.9e-56 S DUF35 OB-fold domain, acyl-CoA-associated
GPNIHGFM_02380 1.1e-239 yoaB EGP Major facilitator Superfamily
GPNIHGFM_02381 6.4e-212 1.1.1.14 E Dehydrogenase
GPNIHGFM_02382 3.2e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_02383 4e-134 K DeoR C terminal sensor domain
GPNIHGFM_02384 9.4e-80 rpiB 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
GPNIHGFM_02385 7.9e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
GPNIHGFM_02386 1.7e-111 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dak2
GPNIHGFM_02387 1e-173 glpX 2.2.1.1, 3.1.3.11, 3.1.3.37 G Bacterial fructose-1,6-bisphosphatase, glpX-encoded
GPNIHGFM_02388 2.6e-166 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
GPNIHGFM_02389 1.3e-176 S Tripartite tricarboxylate transporter family receptor
GPNIHGFM_02391 1.8e-265 S Tripartite tricarboxylate transporter TctA family
GPNIHGFM_02392 6.2e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPNIHGFM_02393 2.4e-181 K Periplasmic binding protein domain
GPNIHGFM_02394 1.8e-97
GPNIHGFM_02395 2.7e-69
GPNIHGFM_02397 4.5e-137 G ABC transporter (permease)
GPNIHGFM_02398 6.1e-138 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02399 3.4e-194 G Bacterial extracellular solute-binding protein
GPNIHGFM_02400 1.6e-207 2.7.13.3 T Histidine kinase
GPNIHGFM_02401 6.9e-154 T helix_turn_helix, arabinose operon control protein
GPNIHGFM_02402 2.1e-165 3.2.1.180 GH88 O Glycosyl Hydrolase Family 88
GPNIHGFM_02403 5.2e-230 S Uncharacterized protein conserved in bacteria (DUF2264)
GPNIHGFM_02404 2.8e-196 S Heparinase II/III-like protein
GPNIHGFM_02405 0.0 hylB 3.2.1.55, 3.2.1.8, 4.2.2.1, 4.2.2.20, 4.2.2.21, 4.2.2.5 CBM6,GH43,PL8 M Glycosyl hydrolase family 59
GPNIHGFM_02406 2.4e-78 yiaB S yiaA/B two helix domain
GPNIHGFM_02408 4.8e-261 yeaV M Belongs to the BCCT transporter (TC 2.A.15) family
GPNIHGFM_02409 1e-86
GPNIHGFM_02410 4.4e-23 2.7.7.19 S Psort location Cytoplasmic, score
GPNIHGFM_02411 3.4e-49 2.7.7.19 S Psort location Cytoplasmic, score
GPNIHGFM_02412 8.9e-34 L RAMP superfamily
GPNIHGFM_02413 5e-83 L RAMP superfamily
GPNIHGFM_02414 1e-58 L RAMP superfamily
GPNIHGFM_02416 4.7e-79 L RAMP superfamily
GPNIHGFM_02417 3.2e-79 S CRISPR-associated endoribonuclease Cas6
GPNIHGFM_02418 3.7e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GPNIHGFM_02419 0.0 cas3 L Metal dependent phosphohydrolases with conserved 'HD' motif.
GPNIHGFM_02421 3.1e-138 cas5d S CRISPR-associated protein (Cas_Cas5)
GPNIHGFM_02422 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
GPNIHGFM_02423 1e-156 csd2 L CRISPR-associated protein Cas7
GPNIHGFM_02424 1.5e-118 cas4 3.1.12.1 L RecB family exonuclease
GPNIHGFM_02425 5.7e-194 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GPNIHGFM_02426 9.6e-46 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GPNIHGFM_02427 8.7e-34
GPNIHGFM_02430 6.9e-75
GPNIHGFM_02431 1.6e-64 K Transcriptional regulator
GPNIHGFM_02432 5.9e-84
GPNIHGFM_02433 7.3e-303
GPNIHGFM_02434 2.1e-52
GPNIHGFM_02435 5.4e-170 S Choline/ethanolamine kinase
GPNIHGFM_02436 1e-87 ykuD S protein conserved in bacteria
GPNIHGFM_02437 6e-211 S Erythromycin esterase
GPNIHGFM_02438 3e-166 NT chemotaxis protein
GPNIHGFM_02439 1.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
GPNIHGFM_02440 2.2e-255 putP E Sodium:solute symporter family
GPNIHGFM_02441 1.4e-189 3.5.3.6 E Amidinotransferase
GPNIHGFM_02442 6.1e-182 K Transcriptional regulator
GPNIHGFM_02443 3.2e-150 V ABC transporter
GPNIHGFM_02444 3.6e-101 S ABC-2 family transporter protein
GPNIHGFM_02445 1.9e-147 K Transcriptional regulator
GPNIHGFM_02446 1.6e-149 yxxF EG EamA-like transporter family
GPNIHGFM_02447 3.4e-183 lacR K Transcriptional regulator
GPNIHGFM_02448 5.3e-234 cycB G COG2182 Maltose-binding periplasmic proteins domains
GPNIHGFM_02449 2.5e-239 malC P COG1175 ABC-type sugar transport systems, permease components
GPNIHGFM_02450 2.4e-145 ganQ P transport
GPNIHGFM_02451 1.7e-234 ganB 3.2.1.89 G arabinogalactan
GPNIHGFM_02452 0.0 lacA 3.2.1.23 G beta-galactosidase
GPNIHGFM_02453 3.4e-128 S response regulator aspartate phosphatase
GPNIHGFM_02455 1e-90 S DinB superfamily
GPNIHGFM_02456 6.4e-204 dapE 3.5.1.18 E Peptidase dimerisation domain
GPNIHGFM_02457 1.5e-197 6.3.5.5 S ATP-grasp domain
GPNIHGFM_02458 1e-64 K helix_turn_helix, mercury resistance
GPNIHGFM_02459 1.4e-54 S Domain of unknown function (DUF4260)
GPNIHGFM_02460 1.5e-155 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylases
GPNIHGFM_02462 1.8e-101 3.5.1.124 S DJ-1/PfpI family
GPNIHGFM_02464 2.4e-153 4.1.2.13 G Fructose-bisphosphate aldolase class-II
GPNIHGFM_02465 8.9e-205 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
GPNIHGFM_02466 3.5e-43 ptxB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
GPNIHGFM_02467 3e-171 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GPNIHGFM_02468 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
GPNIHGFM_02469 8e-63 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNIHGFM_02470 1.7e-257 S Chlorophyllase enzyme
GPNIHGFM_02471 3.5e-132 bceA V ABC transporter, ATP-binding protein
GPNIHGFM_02472 0.0 bceB V ABC transporter (permease)
GPNIHGFM_02473 1.1e-187 gerKC S Spore germination B3/ GerAC like, C-terminal
GPNIHGFM_02474 1.6e-178 gerKB E Spore germination protein
GPNIHGFM_02475 2.5e-190 gerKA EG Spore germination protein
GPNIHGFM_02476 5.2e-08 gerKA EG Spore germination protein
GPNIHGFM_02477 1.1e-151
GPNIHGFM_02478 7.5e-177 ectD 1.14.11.55 Q Phytanoyl-CoA dioxygenase (PhyH)
GPNIHGFM_02479 2.5e-178 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
GPNIHGFM_02480 2.7e-45 G Tripartite ATP-independent periplasmic transporters, DctQ component
GPNIHGFM_02481 3.6e-127 G Bacterial extracellular solute-binding protein, family 7
GPNIHGFM_02482 3.2e-80 kipR K Transcriptional regulator
GPNIHGFM_02483 7.5e-291 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
GPNIHGFM_02484 5.3e-173 feuA P Iron-uptake system-binding protein
GPNIHGFM_02485 9.8e-178 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNIHGFM_02486 2.2e-182 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNIHGFM_02487 3.1e-150 besA S Putative esterase
GPNIHGFM_02488 8.7e-127 I Alpha/beta hydrolase family
GPNIHGFM_02489 7.9e-241 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GPNIHGFM_02490 4.8e-120 tcpP 2.7.11.1 KT Forkhead associated domain
GPNIHGFM_02491 4.3e-155 3.5.2.6 V beta-lactamase
GPNIHGFM_02492 1.5e-131 S Nucleotidyltransferase domain
GPNIHGFM_02493 1.3e-227 hemAT NT chemotaxis protein
GPNIHGFM_02494 2.5e-181 K helix_turn _helix lactose operon repressor
GPNIHGFM_02495 6.8e-153 dkgB S Aldo/keto reductase family
GPNIHGFM_02496 2.1e-169 fhuD P ABC transporter
GPNIHGFM_02497 8.6e-142 K Helix-turn-helix domain
GPNIHGFM_02498 6.3e-55 S Ketosteroid isomerase-related protein
GPNIHGFM_02499 1e-182 MA20_22185 K Transcriptional regulator, LacI family
GPNIHGFM_02500 1.3e-179 S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_02501 2.8e-208 cycB_1 G Bacterial extracellular solute-binding protein
GPNIHGFM_02502 4.6e-166 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02503 5.9e-141 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02504 4.5e-193 G Xylose isomerase
GPNIHGFM_02505 2.8e-155 S Membrane transport protein
GPNIHGFM_02507 3.7e-71 K response regulator
GPNIHGFM_02508 4.1e-28 K response regulator
GPNIHGFM_02509 5.8e-61
GPNIHGFM_02510 1.5e-22
GPNIHGFM_02511 1.1e-86 M1-1022 1.8.5.2 S DoxX
GPNIHGFM_02512 2.9e-276 murE 6.3.2.13 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPNIHGFM_02513 5.1e-148 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GPNIHGFM_02514 1.4e-99 K Bacterial regulatory proteins, tetR family
GPNIHGFM_02515 2.8e-112 yqeB
GPNIHGFM_02516 3.6e-52 K PadR family transcriptional regulator
GPNIHGFM_02517 3.4e-71 V (ABC) transporter
GPNIHGFM_02518 2e-163 V VanW like protein
GPNIHGFM_02520 1.1e-123 yoqW S Belongs to the SOS response-associated peptidase family
GPNIHGFM_02521 1e-176 isp O Belongs to the peptidase S8 family
GPNIHGFM_02522 1.3e-160 yjlA EG Putative multidrug resistance efflux transporter
GPNIHGFM_02523 1.1e-254
GPNIHGFM_02524 7.6e-195 sstT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPNIHGFM_02525 0.0 pepF E oligoendopeptidase
GPNIHGFM_02526 0.0 clpE O Belongs to the ClpA ClpB family
GPNIHGFM_02527 2.4e-78 cwlM 3.5.1.28 M COG3103 SH3 domain protein
GPNIHGFM_02528 2.6e-46
GPNIHGFM_02529 9.9e-283 K Mga helix-turn-helix domain
GPNIHGFM_02532 1e-62 S YolD-like protein
GPNIHGFM_02533 4.3e-220 P Protein of unknown function (DUF418)
GPNIHGFM_02534 2.3e-218 GK ROK family
GPNIHGFM_02535 5.8e-241 cycB_2 G Bacterial extracellular solute-binding protein
GPNIHGFM_02536 3.4e-169 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02537 1.3e-145 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02538 3.1e-184 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_02539 4e-184 S Oxidoreductase family, NAD-binding Rossmann fold
GPNIHGFM_02540 5.6e-147 5.1.3.22, 5.3.1.5 G Xylose isomerase-like TIM barrel
GPNIHGFM_02541 4e-175 S Alpha/beta hydrolase family
GPNIHGFM_02542 1.1e-147 K LysR substrate binding domain
GPNIHGFM_02543 1.2e-119 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
GPNIHGFM_02544 5.8e-217 EGP Major facilitator Superfamily
GPNIHGFM_02545 4.4e-248 EGP Major facilitator Superfamily
GPNIHGFM_02546 1.5e-109 K Bacterial transcriptional repressor C-terminal
GPNIHGFM_02547 1.7e-134 2.1.1.144, 2.1.1.197 S Methyltransferase domain
GPNIHGFM_02548 3e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GPNIHGFM_02549 6.5e-168 fhuD P Periplasmic binding protein
GPNIHGFM_02550 2.7e-172 fhuG 3.6.3.34 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNIHGFM_02551 6.9e-53 isdG 1.14.99.48, 1.14.99.57 C Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
GPNIHGFM_02552 3.3e-105 isdC M NEAr Transporter domain
GPNIHGFM_02553 0.0 M Cell surface protein
GPNIHGFM_02554 5.5e-156 isdE P ABC transporter substrate-binding protein
GPNIHGFM_02555 2.2e-166 fhuB11 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNIHGFM_02556 3.6e-132 fhuC 3.6.3.28, 3.6.3.34 HP ABC transporter, ATP-binding protein
GPNIHGFM_02557 2.2e-137 srtB 3.4.22.70 S Sortase family
GPNIHGFM_02558 1.5e-239 yhdP S COG1253 Hemolysins and related proteins containing CBS domains
GPNIHGFM_02559 2.7e-157 opuAC E Glycine betaine ABC transporter
GPNIHGFM_02560 3.2e-256 S Predicted membrane protein (DUF2254)
GPNIHGFM_02561 2.2e-173 P Catalase
GPNIHGFM_02562 3.4e-168 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
GPNIHGFM_02563 1.8e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GPNIHGFM_02564 5.8e-40
GPNIHGFM_02565 2.5e-37
GPNIHGFM_02566 2.1e-32 T Protein conserved in bacteria
GPNIHGFM_02567 1.9e-81 yokJ S SMI1 / KNR4 family (SUKH-1)
GPNIHGFM_02568 1.8e-60 U LXG domain of WXG superfamily
GPNIHGFM_02569 8.8e-59
GPNIHGFM_02570 1.2e-55 M self proteolysis
GPNIHGFM_02571 1.7e-28 S Family of unknown function (DUF5344)
GPNIHGFM_02572 1.7e-21 S Domain of unknown function (DUF5082)
GPNIHGFM_02575 4.2e-10
GPNIHGFM_02576 8e-52 V efflux transmembrane transporter activity
GPNIHGFM_02577 3.1e-47 ybbA V ABC transporter
GPNIHGFM_02578 1.2e-186 V COG0842 ABC-type multidrug transport system, permease component
GPNIHGFM_02579 4.4e-217 V COG0842 ABC-type multidrug transport system, permease component
GPNIHGFM_02580 2e-169 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
GPNIHGFM_02581 1.1e-107 KT LuxR family transcriptional regulator
GPNIHGFM_02582 8.3e-199 yxjM T Signal transduction histidine kinase
GPNIHGFM_02583 1.6e-88 ttr K GCN5 family acetyltransferase
GPNIHGFM_02584 1.2e-153 fhuD P Periplasmic binding protein
GPNIHGFM_02585 5.3e-201 cpg2 3.4.17.11 E Peptidase dimerisation domain
GPNIHGFM_02586 3e-232 purD 6.3.4.13 F Belongs to the GARS family
GPNIHGFM_02587 9.8e-283 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GPNIHGFM_02588 1.1e-96 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPNIHGFM_02589 3e-190 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GPNIHGFM_02590 1.6e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPNIHGFM_02591 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPNIHGFM_02592 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPNIHGFM_02593 1.4e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPNIHGFM_02594 6.5e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GPNIHGFM_02595 7.9e-249 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPNIHGFM_02596 3.3e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPNIHGFM_02597 4.5e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPNIHGFM_02598 1.9e-127 S CAAX protease self-immunity
GPNIHGFM_02599 1.5e-95 rimL 1.1.1.25 J Acetyltransferase (GNAT) domain
GPNIHGFM_02600 7.5e-120 S PFAM AIG2 family protein
GPNIHGFM_02601 1.1e-99
GPNIHGFM_02602 1.9e-67 S Calcium/calmodulin dependent protein kinase II association domain
GPNIHGFM_02603 1.4e-30 yebG S NETI protein
GPNIHGFM_02604 3.1e-07
GPNIHGFM_02605 1.5e-68 doc S Fic/DOC family
GPNIHGFM_02607 5e-255 tctA S Tripartite tricarboxylate transporter TctA family
GPNIHGFM_02608 1.7e-68 S Tripartite tricarboxylate transporter TctB family
GPNIHGFM_02609 1.9e-186 S Tripartite tricarboxylate transporter family receptor
GPNIHGFM_02610 6.7e-111 citT T response regulator
GPNIHGFM_02611 4.1e-284 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GPNIHGFM_02612 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
GPNIHGFM_02613 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNIHGFM_02614 1.3e-307 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNIHGFM_02615 1.6e-233 G Major facilitator Superfamily
GPNIHGFM_02616 8.7e-20
GPNIHGFM_02618 1e-96 ypbQ S protein conserved in bacteria
GPNIHGFM_02619 1.1e-208 bcsA Q Naringenin-chalcone synthase
GPNIHGFM_02620 1.6e-129 mta K transcriptional
GPNIHGFM_02621 3.3e-112 rimJ2 J Acetyltransferase (GNAT) domain
GPNIHGFM_02622 3.8e-273 uxaC 5.3.1.12 G glucuronate isomerase
GPNIHGFM_02623 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GPNIHGFM_02624 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_02625 5.1e-131 xytR K DeoR C terminal sensor domain
GPNIHGFM_02626 3.5e-86 ywrA P COG2059 Chromate transport protein ChrA
GPNIHGFM_02627 2.7e-103 ywrB P COG2059 Chromate transport protein ChrA
GPNIHGFM_02628 3.8e-156 mqnD S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GPNIHGFM_02629 1.2e-112 mqnB 2.4.2.1, 3.2.2.26, 3.2.2.9 F Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
GPNIHGFM_02630 8.8e-265 lipA1 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPNIHGFM_02631 9.6e-71 K transcriptional antiterminator
GPNIHGFM_02632 3.6e-115 K transcriptional antiterminator
GPNIHGFM_02633 1.2e-51 K transcriptional antiterminator
GPNIHGFM_02634 3.2e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
GPNIHGFM_02635 0.0 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GPNIHGFM_02636 1.7e-161 Q calcium- and calmodulin-responsive adenylate cyclase activity
GPNIHGFM_02637 1.8e-156 proX E Substrate binding domain of ABC-type glycine betaine transport system
GPNIHGFM_02638 3.5e-100 K Belongs to the GbsR family
GPNIHGFM_02639 3.8e-276 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
GPNIHGFM_02640 5.6e-225 gbsB 1.1.1.1 C alcohol dehydrogenase
GPNIHGFM_02641 1.8e-134 yvfI K COG2186 Transcriptional regulators
GPNIHGFM_02642 1.8e-122 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GPNIHGFM_02643 5.6e-272 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
GPNIHGFM_02644 9.4e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GPNIHGFM_02645 0.0 lldP C L-lactate permease
GPNIHGFM_02646 9.1e-14
GPNIHGFM_02647 2.1e-216 cypA C Cytochrome P450
GPNIHGFM_02648 1.6e-253 ydaH H AbgT putative transporter family
GPNIHGFM_02649 0.0 htpG O Molecular chaperone. Has ATPase activity
GPNIHGFM_02650 9.9e-100 yaaI Q Isochorismatase family
GPNIHGFM_02651 4.1e-75 ygaO
GPNIHGFM_02652 1.2e-26 K Transcriptional regulator
GPNIHGFM_02653 9.1e-306 sasH 3.1.3.5, 3.6.1.45 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
GPNIHGFM_02655 3.2e-289 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
GPNIHGFM_02656 1.8e-284 prdR KT Transcriptional regulator
GPNIHGFM_02657 2.8e-168 putA E Proline dehydrogenase
GPNIHGFM_02658 2.1e-149 ykoQ S Calcineurin-like phosphoesterase superfamily domain
GPNIHGFM_02659 3.3e-46 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPNIHGFM_02660 1.2e-286 S proteins of the AP superfamily
GPNIHGFM_02661 7.2e-210 pbuG S permease
GPNIHGFM_02662 9.9e-67
GPNIHGFM_02663 1.7e-173 aph 2.7.11.1 S Phosphotransferase enzyme family
GPNIHGFM_02664 2.2e-216 G Transmembrane secretion effector
GPNIHGFM_02665 6.5e-23 S YfhD-like protein
GPNIHGFM_02666 1e-63 dhaM 2.7.1.121 S PTS system fructose IIA component
GPNIHGFM_02667 7.8e-106 dhaL 2.7.1.121 S Dak2
GPNIHGFM_02668 2.7e-175 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
GPNIHGFM_02669 1.1e-65 M1-431 S Protein of unknown function (DUF1706)
GPNIHGFM_02670 1.3e-73 adcR K Iron dependent repressor, N-terminal DNA binding domain
GPNIHGFM_02671 3.7e-197 yvmA EGP Major Facilitator Superfamily
GPNIHGFM_02672 0.0 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
GPNIHGFM_02673 2.5e-88 3.1.21.3 V Type I restriction modification DNA specificity domain
GPNIHGFM_02674 8.3e-202 hsdM 2.1.1.72 V Type I restriction-modification system
GPNIHGFM_02675 3.8e-151 hsdM 2.1.1.72 V Type I restriction-modification system
GPNIHGFM_02676 5.7e-181 yxeA V FtsX-like permease family
GPNIHGFM_02677 2.3e-111 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
GPNIHGFM_02678 5e-80 K Bacterial regulatory proteins, tetR family
GPNIHGFM_02679 3.9e-20 yisL S UPF0344 protein
GPNIHGFM_02680 1.4e-120 C Nitroreductase family
GPNIHGFM_02681 2.2e-84 tetB EGP Major facilitator Superfamily
GPNIHGFM_02682 1.4e-57 K helix_turn_helix multiple antibiotic resistance protein
GPNIHGFM_02683 4.1e-81 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPNIHGFM_02684 1.3e-36 S Carboxymuconolactone decarboxylase family
GPNIHGFM_02685 4.1e-129 K TIGRFAM RNA polymerase sigma factor, sigma-70 family
GPNIHGFM_02686 7.5e-65 S Erythromycin esterase
GPNIHGFM_02687 4.2e-167 K LysR substrate binding domain
GPNIHGFM_02688 3.3e-186 ord 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
GPNIHGFM_02689 1.8e-235 C Na+/H+ antiporter family
GPNIHGFM_02690 1.2e-76 S glyoxalase bleomycin resistance protein dioxygenase
GPNIHGFM_02691 1.1e-163 ydhU P Catalase
GPNIHGFM_02693 6.5e-145 S Nucleotidyltransferase domain
GPNIHGFM_02695 6.5e-18
GPNIHGFM_02696 3.9e-125 bshB1 S proteins, LmbE homologs
GPNIHGFM_02697 9.3e-195 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
GPNIHGFM_02698 6.1e-189 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GPNIHGFM_02699 1.1e-175 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GPNIHGFM_02700 1.6e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
GPNIHGFM_02701 1.4e-164 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPNIHGFM_02702 3e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GPNIHGFM_02703 1.2e-174 S Tetratricopeptide repeat
GPNIHGFM_02704 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GPNIHGFM_02705 2.2e-243 mtaD 3.5.4.28, 3.5.4.31 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
GPNIHGFM_02706 1.6e-14
GPNIHGFM_02707 4.2e-22 ypmA S Protein of unknown function (DUF4264)
GPNIHGFM_02708 5.3e-81 ypmB S protein conserved in bacteria
GPNIHGFM_02709 7.6e-252 asnS 6.1.1.22 J asparaginyl-tRNA
GPNIHGFM_02710 5.9e-126 dnaD L DNA replication protein DnaD
GPNIHGFM_02711 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPNIHGFM_02712 0.0 ypbR S Dynamin family
GPNIHGFM_02713 0.0 pbp1A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPNIHGFM_02714 8.5e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPNIHGFM_02715 2e-158 yppC S Protein of unknown function (DUF2515)
GPNIHGFM_02717 2.6e-86 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
GPNIHGFM_02718 4.7e-45 yppE S Bacterial domain of unknown function (DUF1798)
GPNIHGFM_02719 6e-15
GPNIHGFM_02720 6.8e-234 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GPNIHGFM_02721 2.8e-96 pfpI 3.5.1.124 S DJ-1/PfpI family
GPNIHGFM_02722 1.7e-168 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GPNIHGFM_02723 3.5e-52 yusE CO cell redox homeostasis
GPNIHGFM_02724 9.3e-77 yphP S Belongs to the UPF0403 family
GPNIHGFM_02725 1.5e-73 CO Thioredoxin-like
GPNIHGFM_02726 7e-138 T Calcineurin-like phosphoesterase superfamily domain
GPNIHGFM_02727 8.5e-143 ypgR C COG0694 Thioredoxin-like proteins and domains
GPNIHGFM_02728 1.4e-28
GPNIHGFM_02729 3.9e-84 ydbS S Bacterial PH domain
GPNIHGFM_02730 2.4e-233 ydbT S Membrane
GPNIHGFM_02731 7.6e-191 S Protein of unknown function (DUF2777)
GPNIHGFM_02732 2.9e-165
GPNIHGFM_02733 5e-126 telA P Belongs to the TelA family
GPNIHGFM_02735 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
GPNIHGFM_02736 1.5e-288 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
GPNIHGFM_02737 1.1e-112 ypjP S YpjP-like protein
GPNIHGFM_02738 1.6e-36
GPNIHGFM_02740 4.6e-61 kapB G Kinase associated protein B
GPNIHGFM_02741 1.9e-153 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPNIHGFM_02743 3.9e-82
GPNIHGFM_02744 1.9e-145 ycsE S hydrolases of the HAD superfamily
GPNIHGFM_02745 3.1e-17
GPNIHGFM_02746 2.2e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
GPNIHGFM_02747 2.7e-106 mhqD S Carboxylesterase
GPNIHGFM_02748 3.9e-80
GPNIHGFM_02749 1.6e-197 gerAC S Spore germination B3/ GerAC like, C-terminal
GPNIHGFM_02750 1.8e-185 gerAB E Spore germination protein
GPNIHGFM_02751 1.2e-258 gerAA EG Spore germination protein
GPNIHGFM_02752 0.0 pepF E oligoendopeptidase F
GPNIHGFM_02753 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
GPNIHGFM_02754 1.6e-216 yprB L RNase_H superfamily
GPNIHGFM_02756 1.7e-94 ypsA S Belongs to the UPF0398 family
GPNIHGFM_02757 2.3e-48 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GPNIHGFM_02758 1e-66 rnhA 3.1.26.4 L An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
GPNIHGFM_02759 3e-38
GPNIHGFM_02760 2.3e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GPNIHGFM_02761 7.4e-175 S Oxidoreductase
GPNIHGFM_02762 2.4e-303 2.2.1.6 EH Thiamine pyrophosphate enzyme, central domain
GPNIHGFM_02763 2.7e-61 pcaC 3.1.1.24, 4.1.1.44 S Carboxymuconolactone decarboxylase family
GPNIHGFM_02764 5.6e-62
GPNIHGFM_02765 6.9e-154 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
GPNIHGFM_02767 2.7e-202 S Spore germination B3/ GerAC like, C-terminal
GPNIHGFM_02768 1.4e-201 E Spore germination protein
GPNIHGFM_02769 9.1e-273 P Spore gernimation protein GerA
GPNIHGFM_02770 1.1e-59 S Src homology 3 domains
GPNIHGFM_02771 2.2e-50
GPNIHGFM_02772 1.3e-287 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Belongs to the FGGY kinase family
GPNIHGFM_02773 3.9e-20 S Protein of unknown function (DUF2564)
GPNIHGFM_02774 1.6e-10 G Transmembrane secretion effector
GPNIHGFM_02775 3.7e-186 G Transmembrane secretion effector
GPNIHGFM_02776 5.9e-84 Q ubiE/COQ5 methyltransferase family
GPNIHGFM_02777 3.3e-52 S Belongs to the HesB IscA family
GPNIHGFM_02778 5.8e-288 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPNIHGFM_02779 8.4e-89 IV02_12955 U MarC family integral membrane protein
GPNIHGFM_02780 1.3e-133 K Helix-turn-helix XRE-family like proteins
GPNIHGFM_02781 1.2e-81 licR 2.7.1.197 GKT Mga helix-turn-helix domain
GPNIHGFM_02782 3.9e-122 licR 2.7.1.197 GKT Mga helix-turn-helix domain
GPNIHGFM_02783 8.7e-73 S Membrane
GPNIHGFM_02784 7.9e-46 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
GPNIHGFM_02785 1.8e-194 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPNIHGFM_02786 2.2e-52 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
GPNIHGFM_02787 1.1e-254 bglH 3.2.1.86 GT1 G Glycosyl hydrolase family 1
GPNIHGFM_02788 1.2e-123 3.2.1.86 GT1 G Glycosyl hydrolase family 1
GPNIHGFM_02789 4.8e-131 3.2.1.86 GT1 G Glycosyl hydrolase family 1
GPNIHGFM_02790 2.8e-148 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_02791 4.1e-184 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GPNIHGFM_02792 8.1e-277 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
GPNIHGFM_02793 1.2e-70 yccU S CoA-binding protein
GPNIHGFM_02794 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPNIHGFM_02795 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPNIHGFM_02796 6.5e-57 S Uncharacterized protein conserved in bacteria (DUF2200)
GPNIHGFM_02797 2.3e-82 dksA T general stress protein
GPNIHGFM_02798 5.3e-201 ytvI S sporulation integral membrane protein YtvI
GPNIHGFM_02799 7.6e-135 motB N Flagellar motor protein
GPNIHGFM_02800 4.1e-139 motA N flagellar motor
GPNIHGFM_02801 1.2e-149 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
GPNIHGFM_02802 5.7e-105 S Golgi phosphoprotein 3 (GPP34)
GPNIHGFM_02803 5.3e-36 K COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit
GPNIHGFM_02804 2.5e-101 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
GPNIHGFM_02805 4.4e-86 C HEAT repeats
GPNIHGFM_02806 2.5e-44 CP_0264 3.2.2.10 S Belongs to the LOG family
GPNIHGFM_02807 4.1e-67 S Bacterial PH domain
GPNIHGFM_02808 2.2e-149 3.4.11.5 I Alpha beta hydrolase
GPNIHGFM_02810 1.2e-17 GM PFAM NAD-dependent epimerase dehydratase
GPNIHGFM_02811 2.4e-32 yfiT S Belongs to the metal hydrolase YfiT family
GPNIHGFM_02812 2.6e-58 E LysE type translocator
GPNIHGFM_02813 1.6e-100 K AraC family transcriptional regulator
GPNIHGFM_02814 4e-12
GPNIHGFM_02815 1.8e-07 S Family of unknown function (DUF5345)
GPNIHGFM_02816 3.3e-92 sigY K Belongs to the sigma-70 factor family. ECF subfamily
GPNIHGFM_02817 9.8e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GPNIHGFM_02818 4.2e-156 yxlF V ABC transporter, ATP-binding protein
GPNIHGFM_02819 5.4e-11 yxlE S Phospholipase_D-nuclease N-terminal
GPNIHGFM_02820 2.8e-79 S Domain of unknown function (DUF4188)
GPNIHGFM_02821 1.7e-90 padR K Virulence activator alpha C-term
GPNIHGFM_02822 2.7e-152 ydeE K AraC family transcriptional regulator
GPNIHGFM_02823 2e-72 S Activator of Hsp90 ATPase homolog 1-like protein
GPNIHGFM_02824 7.3e-49 atl 3.2.1.96, 3.4.17.14, 3.5.1.28, 6.1.1.12 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPNIHGFM_02825 2.6e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GPNIHGFM_02826 4e-276 M Glycosyltransferase like family 2
GPNIHGFM_02827 0.0 tagF 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GPNIHGFM_02828 9e-71 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
GPNIHGFM_02829 4.9e-134 2.7.8.34 I CDP-alcohol phosphatidyltransferase
GPNIHGFM_02830 1.5e-230 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPNIHGFM_02831 1.5e-250 wcaJ M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GPNIHGFM_02832 2e-194 exoA M Glycosyltransferase like family 2
GPNIHGFM_02833 1.3e-129 E lipolytic protein G-D-S-L family
GPNIHGFM_02834 3.9e-63 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
GPNIHGFM_02835 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPNIHGFM_02836 3.4e-191 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPNIHGFM_02837 1.5e-112 ymaB S MutT family
GPNIHGFM_02838 7.7e-97 pncA Q COG1335 Amidases related to nicotinamidase
GPNIHGFM_02839 1.2e-26
GPNIHGFM_02840 1.3e-214 yaaH M Glycoside Hydrolase Family
GPNIHGFM_02841 2.3e-128 IQ Enoyl-(Acyl carrier protein) reductase
GPNIHGFM_02842 3.1e-289 cscA 3.2.1.26, 3.2.1.80 GH32 G invertase
GPNIHGFM_02843 0.0 sacC 3.2.1.26, 3.2.1.80 GH32 G invertase
GPNIHGFM_02844 0.0 lplA5 G Bacterial extracellular solute-binding protein
GPNIHGFM_02845 1.5e-161 lplC7 G COG0395 ABC-type sugar transport system, permease component
GPNIHGFM_02846 4.3e-175 lplB7 G COG4209 ABC-type polysaccharide transport system, permease component
GPNIHGFM_02847 7e-181 scrR K transcriptional
GPNIHGFM_02849 1.9e-108
GPNIHGFM_02850 5.3e-206 msmX E ABC transporter
GPNIHGFM_02851 1.3e-157 araQ P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02852 7.1e-164 araP G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02853 2.7e-244 G Bacterial extracellular solute-binding protein
GPNIHGFM_02854 1.3e-274 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
GPNIHGFM_02855 6.7e-21 K sequence-specific DNA binding
GPNIHGFM_02856 4.8e-52 K sequence-specific DNA binding
GPNIHGFM_02857 2.9e-159 S NYN domain
GPNIHGFM_02858 7.2e-123
GPNIHGFM_02860 7.3e-62 K helix_turn_helix gluconate operon transcriptional repressor
GPNIHGFM_02861 1.5e-121 yhcG V ABC transporter, ATP-binding protein
GPNIHGFM_02862 4.5e-133
GPNIHGFM_02863 2.8e-11
GPNIHGFM_02865 3.8e-20 K sequence-specific DNA binding
GPNIHGFM_02866 1.7e-108 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
GPNIHGFM_02867 1.5e-140 3.1.26.11 S Metallo-beta-lactamase superfamily
GPNIHGFM_02868 5.7e-86 K Transcriptional regulator
GPNIHGFM_02869 9.8e-112 KLT serine threonine protein kinase
GPNIHGFM_02871 2.1e-38
GPNIHGFM_02872 4.6e-205 yhcY 2.7.13.3 T Histidine kinase
GPNIHGFM_02873 3.5e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNIHGFM_02875 3.6e-185 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPNIHGFM_02876 4.6e-126 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNIHGFM_02877 5.9e-100 S Bacteriocin-protection, YdeI or OmpD-Associated
GPNIHGFM_02878 9.7e-161 K WYL domain
GPNIHGFM_02879 7.8e-88 S DinB family
GPNIHGFM_02880 5.8e-149 yidA S hydrolases of the HAD superfamily
GPNIHGFM_02881 2.9e-168 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPNIHGFM_02882 6.1e-210 S Oxidoreductase family, NAD-binding Rossmann fold
GPNIHGFM_02883 7.4e-169 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPNIHGFM_02884 1.2e-106 adaA 3.2.2.21 K Transcriptional regulator
GPNIHGFM_02885 2.7e-94 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPNIHGFM_02891 7.4e-198 UW nuclease activity
GPNIHGFM_02894 1.5e-22
GPNIHGFM_02896 6.6e-176 S Oxidoreductase family, NAD-binding Rossmann fold
GPNIHGFM_02897 7.7e-173 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
GPNIHGFM_02898 1.3e-139 tuaG GT2 M Glycosyltransferase like family 2
GPNIHGFM_02899 1e-69
GPNIHGFM_02900 4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPNIHGFM_02901 1e-249 M -O-antigen
GPNIHGFM_02902 1.8e-54
GPNIHGFM_02903 6.7e-193 M Glycosyl transferases group 1
GPNIHGFM_02904 3.5e-146 exoM S Glycosyl transferase family 2
GPNIHGFM_02905 6.8e-249 S Polysaccharide biosynthesis protein
GPNIHGFM_02906 4.8e-114 sufR K Transcriptional regulator
GPNIHGFM_02907 9.6e-112 sodA 1.15.1.1 P Iron/manganese superoxide dismutases, C-terminal domain
GPNIHGFM_02908 1.7e-38 S Protein of unknown function (DUF1450)
GPNIHGFM_02909 5.5e-23 C 4Fe-4S binding domain
GPNIHGFM_02910 4.5e-68 S Putative glycolipid-binding
GPNIHGFM_02911 5.7e-236 3.5.1.47 S Peptidase dimerisation domain
GPNIHGFM_02912 2.1e-277 abgT H AbgT putative transporter family
GPNIHGFM_02913 1.1e-259 abgB 3.5.1.47 S amidohydrolase
GPNIHGFM_02914 2.8e-238 KT transcriptional regulatory protein
GPNIHGFM_02915 2.4e-139 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
GPNIHGFM_02916 7.9e-205 MA20_04465 4.2.3.1 E Pyridoxal-phosphate dependent enzyme
GPNIHGFM_02917 1.7e-83 M PFAM secretion protein HlyD family protein
GPNIHGFM_02918 2.3e-139 V COG1131 ABC-type multidrug transport system, ATPase component
GPNIHGFM_02919 2.4e-193 V COG0842 ABC-type multidrug transport system, permease component
GPNIHGFM_02920 1e-114 K Transcriptional regulator
GPNIHGFM_02921 2.5e-52 fabH 2.3.1.180 I Chalcone and stilbene synthases, N-terminal domain
GPNIHGFM_02924 4.7e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
GPNIHGFM_02925 4.7e-74
GPNIHGFM_02926 4e-156 kbaY 4.1.2.13, 4.1.2.40 G in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
GPNIHGFM_02927 1.8e-75 fruD 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GPNIHGFM_02928 6.8e-230 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
GPNIHGFM_02929 1.2e-170 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
GPNIHGFM_02930 2.8e-140 rpl K Helix-turn-helix domain, rpiR family
GPNIHGFM_02931 4.2e-161 T Belongs to the universal stress protein A family
GPNIHGFM_02933 2.4e-47
GPNIHGFM_02934 2.4e-56
GPNIHGFM_02935 6.9e-195 potD2 E COG0687 Spermidine putrescine-binding periplasmic protein
GPNIHGFM_02936 6e-166 iunH3 3.2.2.1 F nucleoside hydrolase
GPNIHGFM_02937 2.1e-138 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
GPNIHGFM_02938 6.7e-134 potC3 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_02939 3.7e-196 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GPNIHGFM_02940 4.4e-46 K FCD
GPNIHGFM_02941 3.7e-118 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPNIHGFM_02942 3.2e-28 gloA_3 E COG0346 Lactoylglutathione lyase and related lyases
GPNIHGFM_02943 7.8e-26 L Transposase
GPNIHGFM_02944 3.4e-187 P COG2807 Cyanate permease
GPNIHGFM_02945 3.8e-179 S amine dehydrogenase activity
GPNIHGFM_02946 3.6e-120 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNIHGFM_02947 8.3e-252 T Histidine kinase
GPNIHGFM_02948 2.5e-66 S YtkA-like
GPNIHGFM_02949 1.3e-56 eaeH M LysM domain
GPNIHGFM_02950 4.1e-26 phhB 3.5.4.33, 4.2.1.96 H pterin-4-alpha-carbinolamine dehydratase
GPNIHGFM_02951 2.7e-236 S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GPNIHGFM_02953 2.2e-137 ubiE Q Methyltransferase type 11
GPNIHGFM_02954 9.1e-70 mmyG S dehydrogenases and related proteins
GPNIHGFM_02956 4.5e-32
GPNIHGFM_02957 1.4e-51 S Bacterial PH domain
GPNIHGFM_02958 5.4e-32
GPNIHGFM_02960 7.9e-107 M1-1017 S Protein of unknown function (DUF1129)
GPNIHGFM_02961 1.5e-53 K Transcriptional regulator
GPNIHGFM_02962 5.1e-105 S DUF218 domain
GPNIHGFM_02963 5.7e-147 degV S protein conserved in bacteria
GPNIHGFM_02964 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPNIHGFM_02965 5.6e-40 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPNIHGFM_02966 7.7e-227 yciC S GTPases (G3E family)
GPNIHGFM_02967 5.4e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
GPNIHGFM_02968 7.6e-188 mhqA E COG0346 Lactoylglutathione lyase and related lyases
GPNIHGFM_02969 0.0 ubiD 4.1.1.98 H Belongs to the UbiD family
GPNIHGFM_02970 2.8e-114 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GPNIHGFM_02971 5.6e-132 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GPNIHGFM_02972 4.1e-237 atoE I Short chain fatty acid transporter
GPNIHGFM_02973 4e-187 malR 5.1.1.1 K Transcriptional regulator
GPNIHGFM_02974 4.6e-149 malG P transport
GPNIHGFM_02975 4.3e-247 malC P COG1175 ABC-type sugar transport systems, permease components
GPNIHGFM_02976 5.2e-237 G COG2182 Maltose-binding periplasmic proteins domains
GPNIHGFM_02977 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
GPNIHGFM_02979 3.7e-243 codA 3.5.4.1 F Amidohydrolase family
GPNIHGFM_02980 1.2e-219 codB F cytosine purines uracil thiamine allantoin
GPNIHGFM_02982 9.7e-281 QT COG2508 Regulator of polyketide synthase expression
GPNIHGFM_02983 1.9e-225 lhgO 1.1.99.2 S FAD dependent oxidoreductase
GPNIHGFM_02984 1.6e-254 glcF C Glycolate oxidase
GPNIHGFM_02985 2.9e-265 glcD 1.1.3.15 C Glycolate oxidase subunit
GPNIHGFM_02986 2.7e-121 K COG2186 Transcriptional regulators
GPNIHGFM_02987 6.6e-117 K FCD
GPNIHGFM_02988 0.0 S Tripartite ATP-independent periplasmic transporter, DctM component
GPNIHGFM_02989 5.5e-186 S NMT1-like family
GPNIHGFM_02990 1.2e-155 K Transcriptional regulator
GPNIHGFM_02991 1.9e-200 citA 2.3.3.1 C Belongs to the citrate synthase family
GPNIHGFM_02992 2.1e-206 siaM G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
GPNIHGFM_02993 2.5e-75 G Tripartite ATP-independent periplasmic transporters, DctQ component
GPNIHGFM_02994 6.9e-184 G Bacterial extracellular solute-binding protein, family 7
GPNIHGFM_02995 4.6e-115 K FCD
GPNIHGFM_02996 2.6e-194 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
GPNIHGFM_02997 5.4e-265 NT chemotaxis protein
GPNIHGFM_02998 3.3e-86 paiA K Acetyltransferase (GNAT) domain
GPNIHGFM_02999 2.1e-61 sigV K Belongs to the sigma-70 factor family. ECF subfamily
GPNIHGFM_03000 1.2e-170 S Domain of unknown function (DUF4179)
GPNIHGFM_03001 6.5e-75 S Domain of unknown function (DU1801)
GPNIHGFM_03002 8.7e-113 S CGNR zinc finger
GPNIHGFM_03004 4.1e-83
GPNIHGFM_03005 3.1e-14 K transcriptional
GPNIHGFM_03007 3.8e-268 cstA T Carbon starvation protein
GPNIHGFM_03008 3.6e-134 T COG3279 Response regulator of the LytR AlgR family
GPNIHGFM_03009 0.0 lytS 2.7.13.3 T Histidine kinase
GPNIHGFM_03010 2.4e-104 K Transcriptional regulator
GPNIHGFM_03011 0.0 ydfJ S MMPL family
GPNIHGFM_03012 1.2e-186 S domain protein
GPNIHGFM_03013 2.3e-184 oppF3 E Belongs to the ABC transporter superfamily
GPNIHGFM_03014 1.2e-177 oppD3 P Belongs to the ABC transporter superfamily
GPNIHGFM_03015 2e-166 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_03016 3.7e-171 appB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_03017 0.0 oppA5 E Bacterial extracellular solute-binding proteins, family 5 Middle
GPNIHGFM_03019 8.3e-132 Z012_10580 S Sulfite exporter TauE/SafE
GPNIHGFM_03020 2.9e-19
GPNIHGFM_03022 3.2e-121 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
GPNIHGFM_03023 2.3e-208 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
GPNIHGFM_03024 3.6e-72 siaT_3 G Tripartite ATP-independent periplasmic transporters, DctQ component
GPNIHGFM_03025 1.3e-182 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
GPNIHGFM_03026 4.7e-188 1.1.1.14 E Dehydrogenase
GPNIHGFM_03027 1e-108 K FCD domain
GPNIHGFM_03028 2.4e-240 S Putative nucleotide-binding of sugar-metabolising enzyme
GPNIHGFM_03029 6.3e-159
GPNIHGFM_03030 1.4e-133 K helix_turn_helix, mercury resistance
GPNIHGFM_03031 5.2e-130 Q O-methyltransferase
GPNIHGFM_03032 2.6e-58 L Restriction endonuclease
GPNIHGFM_03033 2.1e-34
GPNIHGFM_03034 2.4e-114 S WLM domain
GPNIHGFM_03035 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
GPNIHGFM_03036 1.1e-111 3.1.21.3 V Type I restriction modification DNA specificity domain
GPNIHGFM_03045 1.5e-07
GPNIHGFM_03053 0.0 yobO M Pectate lyase superfamily protein
GPNIHGFM_03055 1.9e-13 S Protein of unknown function (DUF3533)
GPNIHGFM_03056 1.5e-114 S Protein of unknown function (DUF3533)
GPNIHGFM_03057 1e-134 M1-493 S SnoaL-like domain
GPNIHGFM_03058 3.4e-93 yxcB K Transcriptional regulator C-terminal region
GPNIHGFM_03059 2.8e-45 ybzH K ArsR family transcriptional regulator
GPNIHGFM_03060 1.5e-198 ybcL EGP Major facilitator Superfamily
GPNIHGFM_03061 4.9e-279 yhjG CH FAD binding domain
GPNIHGFM_03062 2.2e-45 J oxidation-reduction process
GPNIHGFM_03063 1.1e-78 yvmB1 K helix_turn_helix multiple antibiotic resistance protein
GPNIHGFM_03064 9.8e-169 S thiolester hydrolase activity
GPNIHGFM_03065 3.9e-231 eph 3.3.2.9 S Epoxide hydrolase
GPNIHGFM_03067 2.8e-154 K DNA-binding protein
GPNIHGFM_03068 2e-133 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNIHGFM_03069 7.1e-242 npr 1.11.1.1 P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GPNIHGFM_03070 2e-101 K Bacterial transcriptional repressor C-terminal
GPNIHGFM_03071 1.7e-19 M Host cell surface-exposed lipoprotein
GPNIHGFM_03073 1e-32 ble E lactoylglutathione lyase activity
GPNIHGFM_03074 2.4e-87 2.7.1.48, 3.1.3.18 F uridine kinase
GPNIHGFM_03075 3.8e-129 K helix_turn_helix, mercury resistance
GPNIHGFM_03076 8.9e-251 pbpE V Beta-lactamase
GPNIHGFM_03077 2.3e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNIHGFM_03078 5.8e-131 IQ Enoyl-(Acyl carrier protein) reductase
GPNIHGFM_03079 2.4e-124 S Nucleotidyltransferase domain
GPNIHGFM_03080 1.8e-38 2.3.1.60 K FR47-like protein
GPNIHGFM_03081 1.2e-56 K Bacterial regulatory proteins, tetR family
GPNIHGFM_03082 5.2e-130 EGP PFAM major facilitator superfamily MFS_1
GPNIHGFM_03083 1.5e-148 cypA Q Cytochrome P450
GPNIHGFM_03084 7.5e-160 K AraC-like ligand binding domain
GPNIHGFM_03085 0.0 pbg 3.2.1.23 G beta-galactosidase
GPNIHGFM_03086 0.0 G alpha-L-rhamnosidase
GPNIHGFM_03087 0.0 K Mga helix-turn-helix domain
GPNIHGFM_03088 2.4e-209 dho 3.5.2.3 S amidohydrolase
GPNIHGFM_03089 3.3e-40 S PRD domain
GPNIHGFM_03090 3.8e-60 S Glycine-rich SFCGS
GPNIHGFM_03091 1e-57 S Domain of unknown function (DUF4312)
GPNIHGFM_03092 1.4e-139 S Domain of unknown function (DUF4311)
GPNIHGFM_03093 1.9e-113 S Domain of unknown function (DUF4310)
GPNIHGFM_03094 2.2e-199 selA 2.9.1.1, 4.3.1.29 E L-seryl-tRNA selenium transferase
GPNIHGFM_03095 3.6e-126 4.1.2.14 S KDGP aldolase
GPNIHGFM_03096 2.8e-69 yhfA S Haloacid dehalogenase-like hydrolase
GPNIHGFM_03097 1.2e-178 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
GPNIHGFM_03098 3.9e-191 scrB 3.2.1.26 GH32 G invertase
GPNIHGFM_03099 2.5e-56 ccpA K helix_turn _helix lactose operon repressor
GPNIHGFM_03100 5.2e-93 K helix_turn_helix, arabinose operon control protein
GPNIHGFM_03101 3.9e-165 G domain, Protein
GPNIHGFM_03102 6.6e-117 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNIHGFM_03103 1.7e-135 T PhoQ Sensor
GPNIHGFM_03104 4e-117 bcrA V Bacitracin ABC transporter ATP-binding protein
GPNIHGFM_03105 1.2e-99 S ABC-2 family transporter protein
GPNIHGFM_03106 3.4e-108 mrsE3 S ABC-2 family transporter protein
GPNIHGFM_03107 2.4e-119 ubiG S 3-demethylubiquinone-9 3-methyltransferase
GPNIHGFM_03108 5e-110 V ABC-2 type transporter
GPNIHGFM_03109 5.1e-133 V AAA domain, putative AbiEii toxin, Type IV TA system
GPNIHGFM_03110 3.2e-114 K helix_turn_helix, mercury resistance
GPNIHGFM_03111 3.6e-141 rocF 3.5.3.1, 3.5.3.11 E Arginase agmatinase formimionoglutamate hydrolase, arginase family
GPNIHGFM_03112 3.4e-58 ydzF K HxlR-like helix-turn-helix
GPNIHGFM_03113 5.4e-54 K Acetyltransferase (GNAT) domain
GPNIHGFM_03114 4.9e-60 K Bacterial regulatory proteins, tetR family
GPNIHGFM_03115 7e-143 K Helix-turn-helix XRE-family like proteins
GPNIHGFM_03116 3.3e-11
GPNIHGFM_03117 1.6e-68 K Helix-turn-helix domain
GPNIHGFM_03118 2e-146 S Alpha beta hydrolase
GPNIHGFM_03119 1.4e-27 T Histidine kinase
GPNIHGFM_03120 3.5e-217 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPNIHGFM_03121 7.9e-126 L DNA alkylation repair enzyme
GPNIHGFM_03122 1.1e-114 S AAA domain
GPNIHGFM_03123 1.3e-91 5.4.2.11 G Phosphoglycerate mutase family
GPNIHGFM_03124 6.3e-194 yxjM T Signal transduction histidine kinase
GPNIHGFM_03125 9.5e-107 KT LuxR family transcriptional regulator
GPNIHGFM_03126 2e-169 V COG1131 ABC-type multidrug transport system, ATPase component
GPNIHGFM_03127 5.5e-215 V ABC-2 family transporter protein
GPNIHGFM_03128 1.6e-189 V ABC-2 type transporter
GPNIHGFM_03129 2.1e-143 gspA M Glycosyl transferase family 8
GPNIHGFM_03130 3.1e-57 yxjI S LURP-one-related
GPNIHGFM_03131 5.1e-142 adcA P Belongs to the bacterial solute-binding protein 9 family
GPNIHGFM_03132 6e-126 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GPNIHGFM_03133 1.6e-94 2.3.1.128 J Acetyltransferase (GNAT) domain
GPNIHGFM_03134 8.4e-48
GPNIHGFM_03135 8.8e-102 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GPNIHGFM_03136 1.2e-269 MA20_17540 P secondary active sulfate transmembrane transporter activity
GPNIHGFM_03137 0.0 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 F Belongs to the 5'-nucleotidase family
GPNIHGFM_03138 4.9e-54 S Regulatory protein YrvL
GPNIHGFM_03139 8.5e-182 yccF K SEC-C motif
GPNIHGFM_03140 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPNIHGFM_03141 1.1e-170 scrR K helix_turn _helix lactose operon repressor
GPNIHGFM_03142 6.8e-297 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
GPNIHGFM_03143 2.3e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNIHGFM_03144 1.9e-180 K Transcriptional regulator
GPNIHGFM_03145 8.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNIHGFM_03146 2e-239 G Tripartite ATP-independent periplasmic transporter, DctM component
GPNIHGFM_03147 8.3e-32
GPNIHGFM_03148 1.7e-116 H Methyltransferase
GPNIHGFM_03149 6.3e-154 K Helix-turn-helix domain, rpiR family
GPNIHGFM_03150 8.4e-154 fldX 1.1.1.31 I Domain of unknown function (DUF1932)
GPNIHGFM_03151 0.0 uidA G Belongs to the glycosyl hydrolase 2 family
GPNIHGFM_03152 8.5e-72 K FCD
GPNIHGFM_03153 5.8e-117 ligC S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_03154 1.2e-111 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
GPNIHGFM_03155 8.3e-43 G Tripartite ATP-independent periplasmic transporters, DctQ component
GPNIHGFM_03156 7.1e-170 G C4-dicarboxylate ABC transporter permease
GPNIHGFM_03158 4.6e-101 G Xylose isomerase-like TIM barrel
GPNIHGFM_03159 3.4e-109 2.3.3.1 C Citrate synthase, C-terminal domain
GPNIHGFM_03160 2.8e-183 C Belongs to the aldehyde dehydrogenase family
GPNIHGFM_03161 2e-111 yjmD_1 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
GPNIHGFM_03162 4.9e-278 2.2.1.6 EH Thiamine pyrophosphate enzyme, central domain
GPNIHGFM_03163 7.4e-193 2.8.3.16 C acyl-CoA transferases carnitine dehydratase
GPNIHGFM_03164 8.1e-55 6.3.3.2 S ASCH
GPNIHGFM_03165 5.7e-77 nsrR K Transcriptional regulator
GPNIHGFM_03166 1e-52 hit FG Scavenger mRNA decapping enzyme C-term binding
GPNIHGFM_03167 8.8e-184 cbrA5 P Ferrichrome ABC transporter substrate-binding protein
GPNIHGFM_03168 0.0 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNIHGFM_03169 7.6e-135 P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
GPNIHGFM_03170 6.6e-143 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_03171 3.3e-189 P NMT1-like family
GPNIHGFM_03173 9.1e-139 P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
GPNIHGFM_03174 1.2e-144 MA20_40340 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_03175 6.3e-182 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GPNIHGFM_03176 1.2e-175 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GPNIHGFM_03177 8.4e-100 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
GPNIHGFM_03178 9.8e-158 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
GPNIHGFM_03179 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
GPNIHGFM_03180 4.7e-85 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
GPNIHGFM_03181 5.2e-242 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
GPNIHGFM_03182 2.3e-226 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GPNIHGFM_03183 1.9e-308 pucR QT COG2508 Regulator of polyketide synthase expression
GPNIHGFM_03184 3e-87 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 S OHCU decarboxylase
GPNIHGFM_03185 1.3e-176 uox 1.7.3.3, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
GPNIHGFM_03186 2.4e-56 pucM 3.5.2.17 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
GPNIHGFM_03187 1.8e-249 S Membrane
GPNIHGFM_03188 5.1e-243 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
GPNIHGFM_03189 6.9e-212 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
GPNIHGFM_03191 6.1e-137 yqjF S Uncharacterized conserved protein (COG2071)
GPNIHGFM_03192 9.5e-46 ycbP S Protein of unknown function (DUF2512)
GPNIHGFM_03193 3.2e-92 yvdQ S Protein of unknown function (DUF3231)
GPNIHGFM_03194 2.7e-227 S Putative esterase
GPNIHGFM_03195 2.5e-158 otrA J Elongation factor G, domain IV
GPNIHGFM_03196 6.4e-81 4.2.1.46, 5.1.3.2 GM NAD dependent epimerase/dehydratase family
GPNIHGFM_03197 1.9e-80 4.2.1.46, 5.1.3.2 GM NAD dependent epimerase/dehydratase family
GPNIHGFM_03198 2.7e-140 S Alpha/beta hydrolase family
GPNIHGFM_03199 4.1e-92 2.3.1.59 K Acetyltransferase (GNAT) domain
GPNIHGFM_03200 3.2e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GPNIHGFM_03201 6.6e-181 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
GPNIHGFM_03202 2.1e-31 ulaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
GPNIHGFM_03203 3.6e-174 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
GPNIHGFM_03204 8.5e-85 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
GPNIHGFM_03205 4.8e-126 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
GPNIHGFM_03206 1.9e-138 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GPNIHGFM_03207 3.6e-185 P ABC transporter substrate-binding protein
GPNIHGFM_03208 4.4e-160 E Glyoxalase-like domain
GPNIHGFM_03209 8.2e-135 MA20_35565 4.1.3.30 G Phosphoenolpyruvate phosphomutase
GPNIHGFM_03210 2.7e-101 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
GPNIHGFM_03211 2.2e-44 sdpR K transcriptional
GPNIHGFM_03212 2.8e-152 K LysR substrate binding domain
GPNIHGFM_03213 1.6e-117 mdmC 2.1.1.104 S O-methyltransferase
GPNIHGFM_03214 7e-262 alsT E Sodium alanine symporter
GPNIHGFM_03215 9.4e-130 IQ Short-chain dehydrogenase reductase sdr
GPNIHGFM_03216 8.9e-78 S Bacterial PH domain
GPNIHGFM_03217 1.6e-13 S Family of unknown function (DUF5344)
GPNIHGFM_03218 1.3e-51 S LXG domain of WXG superfamily
GPNIHGFM_03220 1.7e-47
GPNIHGFM_03221 8.9e-31 S Domain of unknown function (DUF5082)
GPNIHGFM_03222 2.3e-102 K Bacterial regulatory proteins, tetR family
GPNIHGFM_03223 4.1e-200 C NADH:flavin oxidoreductase / NADH oxidase family
GPNIHGFM_03224 3e-225 gerAA EG Spore germination protein
GPNIHGFM_03225 2.2e-183 gerAB E Spore germination protein
GPNIHGFM_03226 1.5e-200 gerAC S Spore germination B3/ GerAC like, C-terminal
GPNIHGFM_03227 1.1e-182 S response regulator aspartate phosphatase
GPNIHGFM_03230 2.3e-304 yfiB3 V ABC transporter
GPNIHGFM_03231 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNIHGFM_03232 5.1e-229 pilS 2.7.13.3 T Histidine kinase
GPNIHGFM_03233 2.1e-290 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPNIHGFM_03234 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPNIHGFM_03235 6.1e-94 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GPNIHGFM_03236 6e-239 agcS E Sodium alanine symporter
GPNIHGFM_03237 2.5e-234 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPNIHGFM_03238 1.2e-304 yngK T Glycosyl hydrolase-like 10
GPNIHGFM_03239 0.0 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
GPNIHGFM_03240 1.1e-267 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNIHGFM_03241 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
GPNIHGFM_03242 1.7e-120 treR K transcriptional
GPNIHGFM_03243 7.8e-85 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
GPNIHGFM_03244 2.9e-204 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GPNIHGFM_03245 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GPNIHGFM_03246 1.9e-133 fruR K Transcriptional regulator
GPNIHGFM_03247 2.1e-163 fruB 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
GPNIHGFM_03248 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
GPNIHGFM_03249 3.2e-181 mreB D Rod-share determining protein MreBH
GPNIHGFM_03250 5.4e-232 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GPNIHGFM_03251 1e-56
GPNIHGFM_03252 2.2e-45 abrB K SpoVT / AbrB like domain
GPNIHGFM_03253 1.4e-40
GPNIHGFM_03254 7.9e-111 rnhA 3.1.26.4 L Caulimovirus viroplasmin
GPNIHGFM_03255 4.4e-242 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
GPNIHGFM_03256 5.9e-244 iucD_1 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
GPNIHGFM_03259 9.1e-294 katB 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
GPNIHGFM_03260 0.0 pepF2 E COG1164 Oligoendopeptidase F
GPNIHGFM_03261 3.7e-108
GPNIHGFM_03262 8.1e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
GPNIHGFM_03263 2.9e-246 cydA 1.10.3.14 C oxidase, subunit
GPNIHGFM_03264 2.2e-21 S Fur-regulated basic protein B
GPNIHGFM_03267 4.1e-147 yfkD S YfkD-like protein
GPNIHGFM_03268 4.7e-218 yfkA S YfkB-like domain
GPNIHGFM_03269 4.1e-113 gpmB 5.4.2.11 G Belongs to the phosphoglycerate mutase family
GPNIHGFM_03270 7.5e-242 yhdP S COG1253 Hemolysins and related proteins containing CBS domains
GPNIHGFM_03271 1.7e-140 S Domain of unknown function (DUF368)
GPNIHGFM_03272 3e-147 pdaA G deacetylase
GPNIHGFM_03274 1.6e-284 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPNIHGFM_03275 5.4e-164 ahpF 1.8.1.9 O Pyridine nucleotide-disulphide oxidoreductase
GPNIHGFM_03276 1.6e-70 ywgB K Transcriptional regulator
GPNIHGFM_03277 4.5e-85 G Xylose isomerase-like TIM barrel
GPNIHGFM_03278 7.8e-114 surE 3.1.3.5 S Survival protein SurE
GPNIHGFM_03279 1.5e-136 afuA P Bacterial extracellular solute-binding protein
GPNIHGFM_03280 1.1e-189 afuB2 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_03281 1.5e-136 3.6.3.30 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GPNIHGFM_03283 1.6e-61
GPNIHGFM_03284 2.1e-271 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPNIHGFM_03285 2e-202 mccF 3.4.17.13 V LD-carboxypeptidase
GPNIHGFM_03286 5.5e-49
GPNIHGFM_03287 2.5e-169 yfhF S nucleoside-diphosphate sugar epimerase
GPNIHGFM_03288 3.9e-145 recX 2.4.1.337 GT4 S Modulates RecA activity
GPNIHGFM_03289 5.2e-53 yfhH S Protein of unknown function (DUF1811)
GPNIHGFM_03290 1.2e-21 S YpzG-like protein
GPNIHGFM_03292 1.8e-189 yfhP S membrane-bound metal-dependent
GPNIHGFM_03293 4.3e-208 mutY L A G-specific
GPNIHGFM_03294 1.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_03295 9.1e-59
GPNIHGFM_03296 4e-19 yfhS
GPNIHGFM_03297 1.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_03298 6e-15 S Small, acid-soluble spore protein, gamma-type
GPNIHGFM_03299 1.5e-102 ygaC J Belongs to the UPF0374 family
GPNIHGFM_03300 0.0 ygaD V ABC transporter
GPNIHGFM_03301 7e-187 ygaE S Membrane
GPNIHGFM_03302 8.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
GPNIHGFM_03303 8.1e-87 bcp 1.11.1.15 O Peroxiredoxin
GPNIHGFM_03304 7.5e-172 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPNIHGFM_03305 2.7e-48 S Cyclic-di-AMP receptor
GPNIHGFM_03306 1.5e-79 perR P Belongs to the Fur family
GPNIHGFM_03307 5.2e-57 ygzB S UPF0295 protein
GPNIHGFM_03309 1.9e-69 puuR K sequence-specific DNA binding
GPNIHGFM_03310 1.4e-66 puuR K sequence-specific DNA binding
GPNIHGFM_03311 9.2e-190 V Domain of unknown function (DUF3471)
GPNIHGFM_03312 1.3e-120 sapB S MgtC SapB transporter
GPNIHGFM_03313 2.1e-58 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPNIHGFM_03314 1.7e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPNIHGFM_03315 4.4e-211 megL 2.5.1.48, 2.5.1.49, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
GPNIHGFM_03317 5e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPNIHGFM_03318 3.9e-81 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
GPNIHGFM_03319 3.2e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
GPNIHGFM_03320 1.2e-85 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GPNIHGFM_03321 7.9e-180 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPNIHGFM_03322 1.6e-303 ydiF S ABC transporter
GPNIHGFM_03323 8.9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GPNIHGFM_03324 1.4e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GPNIHGFM_03325 7.9e-130 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPNIHGFM_03326 1.9e-181 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPNIHGFM_03327 3.9e-111 metI P COG2011 ABC-type metal ion transport system, permease component
GPNIHGFM_03328 5.5e-139 P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
GPNIHGFM_03329 2.3e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
GPNIHGFM_03330 8.9e-117 ydiL S CAAX protease self-immunity
GPNIHGFM_03331 5.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPNIHGFM_03332 6.4e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GPNIHGFM_03333 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
GPNIHGFM_03334 5.3e-72 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GPNIHGFM_03335 1.4e-41 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
GPNIHGFM_03336 1.9e-223 ulaA S PTS system ascorbate-specific transporter subunit IIC
GPNIHGFM_03337 8.8e-128 S carbohydrate derivative metabolic process
GPNIHGFM_03338 1.3e-120 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPNIHGFM_03339 4.2e-144 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GPNIHGFM_03340 8.4e-268 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
GPNIHGFM_03341 8.7e-87 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GPNIHGFM_03342 1.8e-96 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GPNIHGFM_03343 1.3e-82 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
GPNIHGFM_03344 2.2e-182 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPNIHGFM_03345 7.6e-236 moeA 2.10.1.1 H molybdopterin
GPNIHGFM_03346 5.3e-87 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
GPNIHGFM_03347 1.1e-74 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
GPNIHGFM_03348 6.9e-34 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPNIHGFM_03349 3e-137 focA P Formate/nitrite transporter
GPNIHGFM_03350 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
GPNIHGFM_03351 1.8e-105 yjgD S Protein of unknown function (DUF1641)
GPNIHGFM_03352 1.1e-133 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPNIHGFM_03353 1.1e-76 MA20_19235 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
GPNIHGFM_03356 0.0 yfhO S Bacterial membrane protein YfhO
GPNIHGFM_03357 1.2e-68 wxcN GT2 S GtrA-like protein
GPNIHGFM_03358 2.3e-181 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GPNIHGFM_03359 1.6e-151 S Haloacid dehalogenase-like hydrolase
GPNIHGFM_03360 1.3e-132
GPNIHGFM_03361 1e-148 ehuB ET Bacterial periplasmic substrate-binding proteins
GPNIHGFM_03362 6.1e-112 ehuC E Binding-protein-dependent transport system inner membrane component
GPNIHGFM_03363 1.7e-117 ehuD E Binding-protein-dependent transport system inner membrane component
GPNIHGFM_03364 5.8e-149 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GPNIHGFM_03365 2.5e-71 wecC 1.1.1.336 M ArpU family transcriptional regulator
GPNIHGFM_03366 1.5e-244 malK 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GPNIHGFM_03367 1.2e-110 dcuR T COG4565 Response regulator of citrate malate metabolism
GPNIHGFM_03368 7.9e-244 maeN C COG3493 Na citrate symporter
GPNIHGFM_03369 1.3e-210 mez_1 1.1.1.38 C Malate dehydrogenase
GPNIHGFM_03370 8.7e-55 S Short C-terminal domain
GPNIHGFM_03371 1.3e-70
GPNIHGFM_03372 8.2e-76
GPNIHGFM_03373 5.4e-115 D Phage tail tape measure protein, TP901 family
GPNIHGFM_03374 2.6e-132 S Phage tail protein
GPNIHGFM_03375 0.0 L Phage minor structural protein
GPNIHGFM_03377 2.7e-72 S Bacteriophage holin family
GPNIHGFM_03378 3.7e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPNIHGFM_03379 3.3e-106 C nitroreductase
GPNIHGFM_03380 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
GPNIHGFM_03383 3e-181 3.1.4.53 Q Calcineurin-like phosphoesterase
GPNIHGFM_03384 4.9e-99 CO Thioredoxin
GPNIHGFM_03385 4.5e-73 L HNH endonuclease
GPNIHGFM_03386 1.7e-265 G beta-fructofuranosidase activity
GPNIHGFM_03387 1.2e-135 T helix_turn_helix, arabinose operon control protein
GPNIHGFM_03388 0.0 2.7.13.3 T Histidine kinase
GPNIHGFM_03389 1.6e-246 G Bacterial extracellular solute-binding protein
GPNIHGFM_03390 4.7e-171 U Binding-protein-dependent transport system inner membrane component
GPNIHGFM_03391 4.5e-149 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_03392 3.3e-258 C FAD dependent oxidoreductase
GPNIHGFM_03393 3.1e-253 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GPNIHGFM_03394 5.7e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNIHGFM_03395 2.5e-138 glvR K Helix-turn-helix domain, rpiR family
GPNIHGFM_03396 1.9e-70 S Protein of unknown function (DUF1648)
GPNIHGFM_03397 1.9e-75
GPNIHGFM_03398 8.2e-09
GPNIHGFM_03399 2e-37 yqjY K Acetyltransferase (GNAT) domain
GPNIHGFM_03400 7.9e-174 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
GPNIHGFM_03401 6.2e-140 K COG1349 Transcriptional regulators of sugar metabolism
GPNIHGFM_03402 5.4e-78 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GPNIHGFM_03403 2.3e-41 gatB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
GPNIHGFM_03404 1.3e-238 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
GPNIHGFM_03405 3.8e-193 gatD 1.1.1.14, 1.1.1.251 C Alcohol dehydrogenase GroES-like domain
GPNIHGFM_03406 5.2e-156 kbaY 4.1.2.13, 4.1.2.40 G in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
GPNIHGFM_03407 6.2e-55 yyaQ S Protein conserved in bacteria
GPNIHGFM_03408 3.7e-104 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
GPNIHGFM_03409 7.8e-61 yoaS S membrane
GPNIHGFM_03410 2.2e-29 K Transcriptional regulator
GPNIHGFM_03411 1e-137 yoaT S Protein of unknown function (DUF817)
GPNIHGFM_03413 8.9e-24 uppS 2.5.1.31, 2.5.1.89 H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids
GPNIHGFM_03414 6.9e-90 K Helix-turn-helix domain
GPNIHGFM_03415 5.1e-157 rspA 4.2.1.8 M Belongs to the mandelate racemase muconate lactonizing enzyme family
GPNIHGFM_03416 1.2e-98 3.4.22.70 M Sortase family
GPNIHGFM_03417 1.1e-53 K Helix-turn-helix XRE-family like proteins
GPNIHGFM_03419 4.4e-246 E Bacterial extracellular solute-binding proteins, family 5 Middle
GPNIHGFM_03420 1.4e-143 P Binding-protein-dependent transport system inner membrane component
GPNIHGFM_03421 5.3e-127 EP N-terminal TM domain of oligopeptide transport permease C
GPNIHGFM_03422 8.3e-142 oppD P Belongs to the ABC transporter superfamily
GPNIHGFM_03423 2.5e-152 E Belongs to the ABC transporter superfamily
GPNIHGFM_03424 5.4e-137 cpg2 3.4.17.11 E Peptidase dimerisation domain
GPNIHGFM_03425 0.0 msbA2 3.6.3.44 V ABC transporter
GPNIHGFM_03426 1.1e-172 XK27_06795 K sequence-specific DNA binding
GPNIHGFM_03428 0.0 spaB S Lantibiotic dehydratase, C terminus
GPNIHGFM_03429 9.9e-263 spaC1 V Lanthionine synthetase C-like protein
GPNIHGFM_03430 1.2e-103 4.1.1.36, 6.3.2.5 H Flavoprotein
GPNIHGFM_03431 7.7e-129 V AAA domain, putative AbiEii toxin, Type IV TA system
GPNIHGFM_03432 1.4e-129 S ABC-2 family transporter protein
GPNIHGFM_03433 1.1e-130
GPNIHGFM_03434 1.8e-124 T Transcriptional regulatory protein, C terminal
GPNIHGFM_03435 1e-241 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
GPNIHGFM_03436 9.3e-44 S Metallo-beta-lactamase superfamily
GPNIHGFM_03438 2e-35 comEA L Helix-hairpin-helix motif
GPNIHGFM_03440 1.6e-174 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
GPNIHGFM_03441 2.8e-182 rbsR K transcriptional
GPNIHGFM_03442 1e-154 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPNIHGFM_03443 6.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GPNIHGFM_03444 2.7e-277 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
GPNIHGFM_03445 6.3e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
GPNIHGFM_03446 2.9e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
GPNIHGFM_03447 9.7e-118
GPNIHGFM_03448 1.5e-72 ctsR K Belongs to the CtsR family
GPNIHGFM_03449 1.3e-93 mcsA 2.7.14.1 S protein with conserved CXXC pairs
GPNIHGFM_03450 2.4e-195 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
GPNIHGFM_03451 0.0 clpC O Belongs to the ClpA ClpB family
GPNIHGFM_03452 5.8e-250 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPNIHGFM_03453 2.7e-194 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GPNIHGFM_03454 2e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
GPNIHGFM_03455 1.9e-116 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GPNIHGFM_03456 6.1e-82 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
GPNIHGFM_03457 6.9e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPNIHGFM_03458 9.3e-121 cysE 2.3.1.30 E Serine acetyltransferase
GPNIHGFM_03459 8.2e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPNIHGFM_03460 5.7e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GPNIHGFM_03461 1.2e-143 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPNIHGFM_03462 4.9e-85 yacP S RNA-binding protein containing a PIN domain
GPNIHGFM_03463 3.6e-117 sigH K Belongs to the sigma-70 factor family
GPNIHGFM_03464 6.1e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GPNIHGFM_03465 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
GPNIHGFM_03466 6.3e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPNIHGFM_03467 9.4e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GPNIHGFM_03468 3.5e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPNIHGFM_03469 3.2e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GPNIHGFM_03470 2.6e-115 rsmC 2.1.1.172 J Methyltransferase
GPNIHGFM_03471 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPNIHGFM_03472 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPNIHGFM_03473 5e-35 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
GPNIHGFM_03474 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPNIHGFM_03475 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GPNIHGFM_03476 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPNIHGFM_03477 4.7e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPNIHGFM_03478 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
GPNIHGFM_03479 1.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPNIHGFM_03480 1e-105 rplD J Forms part of the polypeptide exit tunnel
GPNIHGFM_03481 2.3e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GPNIHGFM_03482 2.2e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPNIHGFM_03483 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPNIHGFM_03484 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPNIHGFM_03485 8.7e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPNIHGFM_03486 4.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPNIHGFM_03487 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
GPNIHGFM_03488 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPNIHGFM_03489 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPNIHGFM_03490 6.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPNIHGFM_03491 2.3e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPNIHGFM_03492 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPNIHGFM_03493 4.9e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPNIHGFM_03494 1.3e-60 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPNIHGFM_03495 4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPNIHGFM_03496 2.7e-25 rpmD J Ribosomal protein L30
GPNIHGFM_03497 3.3e-74 rplO J binds to the 23S rRNA
GPNIHGFM_03498 1.8e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GPNIHGFM_03499 8.6e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GPNIHGFM_03500 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
GPNIHGFM_03501 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPNIHGFM_03502 1.4e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GPNIHGFM_03503 1.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPNIHGFM_03504 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPNIHGFM_03505 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPNIHGFM_03506 4.7e-58 rplQ J Ribosomal protein L17
GPNIHGFM_03507 4.7e-157 ecfA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPNIHGFM_03508 2e-144 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPNIHGFM_03509 1.1e-133 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPNIHGFM_03510 3.8e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GPNIHGFM_03511 4.4e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPNIHGFM_03512 1.7e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
GPNIHGFM_03513 8.9e-82 S Protein of unknown function (DUF2975)
GPNIHGFM_03514 1.6e-29 yozG K Transcriptional regulator
GPNIHGFM_03516 5.7e-70 guaA J Acetyltransferase (GNAT) domain
GPNIHGFM_03517 8.9e-80 ybaK S Protein of unknown function (DUF2521)
GPNIHGFM_03518 4.4e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPNIHGFM_03519 1.1e-150 glcT K antiterminator
GPNIHGFM_03520 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNIHGFM_03521 7.2e-192 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
GPNIHGFM_03522 6.7e-166 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
GPNIHGFM_03523 2.8e-22 K MarR family transcriptional regulator
GPNIHGFM_03524 3.9e-21 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPNIHGFM_03525 5.9e-75 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GPNIHGFM_03526 2.8e-30 licB 2.7.1.196, 2.7.1.205 G PFAM Phosphotransferase system, lactose cellobiose-specific IIB subunit
GPNIHGFM_03527 9.3e-173 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPNIHGFM_03528 8.6e-73 ywpJ_2 S Sucrose-6F-phosphate phosphohydrolase
GPNIHGFM_03529 2.7e-171 M1-530 S Protein of unknown function (DUF4127)
GPNIHGFM_03530 4.5e-93 rpiR K transcriptional regulator, RpiR family
GPNIHGFM_03531 1.5e-58 gerD S Spore gernimation protein
GPNIHGFM_03532 1.7e-100 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
GPNIHGFM_03533 2.9e-142 pdaB 3.5.1.104 G Polysaccharide deacetylase
GPNIHGFM_03534 1.3e-33
GPNIHGFM_03535 3.4e-21 rimL 2.3.1.128 J Acetyltransferase (GNAT) domain
GPNIHGFM_03536 5.9e-09 rimL 2.3.1.128 J Acetyltransferase (GNAT) domain
GPNIHGFM_03537 2.1e-191 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
GPNIHGFM_03538 1.9e-104 E GDSL-like Lipase/Acylhydrolase
GPNIHGFM_03539 3.8e-290 E COG0747 ABC-type dipeptide transport system, periplasmic component
GPNIHGFM_03542 1.2e-07
GPNIHGFM_03544 1.5e-07
GPNIHGFM_03549 5.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
GPNIHGFM_03550 2.1e-120 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
GPNIHGFM_03551 5.7e-144 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPNIHGFM_03552 5.2e-218 ybbR S protein conserved in bacteria
GPNIHGFM_03553 4e-248 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPNIHGFM_03555 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GPNIHGFM_03556 3.9e-153 ybfI K AraC-like ligand binding domain
GPNIHGFM_03557 1e-173 E Proline dehydrogenase
GPNIHGFM_03558 1.6e-196 V Beta-lactamase
GPNIHGFM_03559 2.6e-32 2.7.1.163 S Aminoglycoside phosphotransferase
GPNIHGFM_03560 1.5e-174 2.7.1.163 S Aminoglycoside phosphotransferase
GPNIHGFM_03561 1.6e-73 K SpoVT / AbrB like domain
GPNIHGFM_03562 2.4e-220 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GPNIHGFM_03563 9.5e-141 V ABC transporter, ATP-binding protein
GPNIHGFM_03564 0.0 V FtsX-like permease family
GPNIHGFM_03565 2.5e-121 T Transcriptional regulatory protein, C terminal
GPNIHGFM_03566 6.8e-187 T Histidine kinase-like ATPases
GPNIHGFM_03567 2e-107 K Bacterial regulatory proteins, tetR family
GPNIHGFM_03568 3.1e-224 mefE EGP Transmembrane secretion effector
GPNIHGFM_03569 0.0 V FtsX-like permease family
GPNIHGFM_03570 3.6e-132 V ABC transporter
GPNIHGFM_03571 8.5e-55 ytrA K GntR family transcriptional regulator
GPNIHGFM_03572 1.8e-156 V ABC transporter, ATP-binding protein
GPNIHGFM_03573 4.1e-91 S ABC-2 family transporter protein
GPNIHGFM_03574 1.9e-175 gluQ 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPNIHGFM_03575 2.5e-153 bla 3.5.2.6 V beta-lactamase
GPNIHGFM_03576 2.6e-303 blaR 3.5.2.6 KTV BlaR1 peptidase M56
GPNIHGFM_03577 6.6e-63 blaI K Penicillinase repressor
GPNIHGFM_03578 8.5e-142 aadD H KNTase C-terminal domain
GPNIHGFM_03579 1.4e-62 cadC K transcriptional
GPNIHGFM_03580 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
GPNIHGFM_03581 6.4e-193 P Oxidoreductase
GPNIHGFM_03582 2.3e-82 2.3.1.128 J Acetyltransferase (GNAT) domain
GPNIHGFM_03583 1.8e-79
GPNIHGFM_03584 3.1e-136 Q ubiE/COQ5 methyltransferase family
GPNIHGFM_03585 7e-181 trpS 6.1.1.2 J Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GPNIHGFM_03586 1.4e-102 Q SAM-dependent methyltransferase
GPNIHGFM_03587 2.3e-140 ydfC EG EamA-like transporter family
GPNIHGFM_03588 9.7e-136 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNIHGFM_03589 4.6e-106 panZ K Acetyltransferase (GNAT) domain
GPNIHGFM_03590 5.9e-64
GPNIHGFM_03591 9.3e-69 S Protein of unknown function (DUF2512)
GPNIHGFM_03592 1.1e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
GPNIHGFM_03593 1.2e-82 2.3.1.128 J Acetyltransferase (GNAT) domain
GPNIHGFM_03594 1.1e-297 siaT_1 S Tripartite ATP-independent periplasmic transporter, DctM component
GPNIHGFM_03595 2.6e-52 S Domain of unknown function (DUF1850)
GPNIHGFM_03596 8.9e-120 thyA S NMT1-like family
GPNIHGFM_03597 4e-302 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
GPNIHGFM_03598 5.2e-116 ktrA P COG0569 K transport systems, NAD-binding component
GPNIHGFM_03599 3.6e-165 I alpha/beta hydrolase fold
GPNIHGFM_03600 2.7e-211 F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPNIHGFM_03601 2.8e-96 adk 2.7.4.3 F topology modulation protein
GPNIHGFM_03604 2.1e-85 ftnA 1.16.3.2 P Iron-storage protein
GPNIHGFM_03605 2.7e-157 yueF S transporter activity
GPNIHGFM_03606 1.1e-276 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPNIHGFM_03607 1.9e-139 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
GPNIHGFM_03608 7.2e-169 yfhM S Alpha beta hydrolase
GPNIHGFM_03609 2.3e-224 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPNIHGFM_03611 2.8e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
GPNIHGFM_03612 3.4e-233 K Helix-turn-helix XRE-family like proteins
GPNIHGFM_03613 1.2e-103 cwlK M Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin
GPNIHGFM_03614 2.8e-247 yeeF E Amino acid permease
GPNIHGFM_03615 3.4e-157 sseA 2.8.1.1, 2.8.1.2 P sulfurtransferase
GPNIHGFM_03616 5.8e-225 QT Transcriptional regulator
GPNIHGFM_03617 1.3e-194 ald 1.4.1.1 E Belongs to the AlaDH PNT family
GPNIHGFM_03618 5.1e-198 pgl 3.1.1.31 G 6-phosphogluconolactonase
GPNIHGFM_03619 4.8e-152 rarD S -transporter
GPNIHGFM_03620 1.2e-149 dppA E D-aminopeptidase
GPNIHGFM_03621 4e-162 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_03622 3.3e-172 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_03623 2.6e-183 dppD P Belongs to the ABC transporter superfamily
GPNIHGFM_03624 0.0 dppE E ABC transporter substrate-binding protein
GPNIHGFM_03625 1.3e-173 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
GPNIHGFM_03626 9.9e-166 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GPNIHGFM_03627 1.2e-180 ykfD E Belongs to the ABC transporter superfamily
GPNIHGFM_03628 2e-58 hxlR K transcriptional
GPNIHGFM_03629 8.7e-110 S Nitroreductase family
GPNIHGFM_03630 5.1e-130 T PhoQ Sensor
GPNIHGFM_03631 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GPNIHGFM_03632 5.1e-64 mnhB2 P antiporter activity
GPNIHGFM_03633 4.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNIHGFM_03634 1.1e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNIHGFM_03635 6.4e-85 mrpE P Na+/H+ ion antiporter subunit
GPNIHGFM_03636 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNIHGFM_03637 3e-58 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
GPNIHGFM_03638 3.5e-157 S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
GPNIHGFM_03639 5e-192 G Xylose isomerase
GPNIHGFM_03640 2.5e-189 S Oxidoreductase family, C-terminal alpha/beta domain
GPNIHGFM_03641 2.1e-137 G Xylose isomerase-like TIM barrel
GPNIHGFM_03642 1.4e-212 S Winged helix DNA-binding domain
GPNIHGFM_03643 2.8e-106 S Integral membrane protein
GPNIHGFM_03644 3.2e-47
GPNIHGFM_03645 3.8e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
GPNIHGFM_03646 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GPNIHGFM_03647 5.7e-101 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPNIHGFM_03648 1.4e-128 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
GPNIHGFM_03649 1.3e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GPNIHGFM_03650 2.6e-186 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
GPNIHGFM_03651 4.8e-198 L reverse transcriptase
GPNIHGFM_03652 7.5e-225 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPNIHGFM_03653 8e-25 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
GPNIHGFM_03654 1.3e-55 ndoA L Toxic component of a toxin-antitoxin (TA) module
GPNIHGFM_03655 5.8e-141 rsbR T Positive regulator of sigma-B
GPNIHGFM_03656 1.3e-52 rsbS T antagonist
GPNIHGFM_03657 1.4e-72 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
GPNIHGFM_03658 9e-184 rsbU 3.1.3.3 KT phosphatase
GPNIHGFM_03659 3.2e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
GPNIHGFM_03660 1.1e-81 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
GPNIHGFM_03661 4.3e-141 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNIHGFM_03662 9.4e-115 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
GPNIHGFM_03663 0.0 yhgF K COG2183 Transcriptional accessory protein
GPNIHGFM_03664 3.9e-08
GPNIHGFM_03665 4.7e-87 ydcK S Belongs to the SprT family
GPNIHGFM_03672 5e-60 Q ubiE/COQ5 methyltransferase family
GPNIHGFM_03673 6.1e-96 yrkC G Cupin domain
GPNIHGFM_03674 1.7e-97 S TraX protein
GPNIHGFM_03675 2.7e-45
GPNIHGFM_03676 1.6e-274 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPNIHGFM_03677 1.5e-77 yuiD S protein conserved in bacteria
GPNIHGFM_03678 1.7e-108 yuiC S protein conserved in bacteria
GPNIHGFM_03679 2.2e-46 yuiB S Putative membrane protein
GPNIHGFM_03680 2.9e-229 yumB 1.6.99.3 C NADH dehydrogenase
GPNIHGFM_03681 2.1e-185 ycgT 1.18.1.2, 1.19.1.1 C reductase
GPNIHGFM_03682 6e-205 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
GPNIHGFM_03683 3.7e-70 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
GPNIHGFM_03684 0.0 mtlR K transcriptional regulator, MtlR
GPNIHGFM_03685 4.9e-307 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
GPNIHGFM_03686 3.6e-154 yckB ET Belongs to the bacterial solute-binding protein 3 family
GPNIHGFM_03687 1.8e-108 yecS P COG0765 ABC-type amino acid transport system, permease component
GPNIHGFM_03688 2.9e-60 erpA S Belongs to the HesB IscA family
GPNIHGFM_03689 7.6e-09 S Spo0E like sporulation regulatory protein
GPNIHGFM_03690 1.9e-208 mqnE 1.21.98.1, 2.5.1.120, 2.5.1.77 H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GPNIHGFM_03691 2.9e-159 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPNIHGFM_03692 1.4e-42
GPNIHGFM_03693 7.6e-41 yuzB S Belongs to the UPF0349 family
GPNIHGFM_03694 0.0 yutJ 1.6.99.3 C NADH dehydrogenase
GPNIHGFM_03695 2.8e-51 yuzD S protein conserved in bacteria
GPNIHGFM_03696 9.7e-36 yutI O COG0694 Thioredoxin-like proteins and domains
GPNIHGFM_03697 5.2e-159 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GPNIHGFM_03698 1.5e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPNIHGFM_03699 6.7e-238 hom 1.1.1.3 E homoserine dehydrogenase
GPNIHGFM_03700 2e-202 yutH S Spore coat protein
GPNIHGFM_03701 4.6e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
GPNIHGFM_03702 1.2e-129 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GPNIHGFM_03703 2.4e-72 yutE S Protein of unknown function DUF86
GPNIHGFM_03704 1.3e-43
GPNIHGFM_03705 3.7e-50 yutD S protein conserved in bacteria
GPNIHGFM_03706 5.7e-92 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPNIHGFM_03707 1.7e-173 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPNIHGFM_03708 5.3e-200 lytH M Peptidase, M23
GPNIHGFM_03709 9.2e-277 nhaC C Na+/H+ antiporter family
GPNIHGFM_03710 2.8e-137 yunB S Sporulation protein YunB (Spo_YunB)
GPNIHGFM_03711 9e-89 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPNIHGFM_03712 6.2e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GPNIHGFM_03713 9.9e-49 yunC S Domain of unknown function (DUF1805)
GPNIHGFM_03714 2.1e-257 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
GPNIHGFM_03715 3.5e-138 yunE S membrane transporter protein
GPNIHGFM_03716 4.2e-166 yunF S Protein of unknown function DUF72
GPNIHGFM_03717 1.2e-64 S Domain of unknown function (DUF5082)
GPNIHGFM_03718 1.9e-48
GPNIHGFM_03719 3.6e-148
GPNIHGFM_03720 2.2e-07
GPNIHGFM_03721 1.1e-40
GPNIHGFM_03722 9.1e-40
GPNIHGFM_03723 6.8e-43
GPNIHGFM_03724 4.1e-161 S LXG domain of WXG superfamily
GPNIHGFM_03725 7.5e-40 S Family of unknown function (DUF5344)
GPNIHGFM_03726 1.2e-37 S Pathogenicity locus
GPNIHGFM_03727 1.2e-64 H RibD C-terminal domain
GPNIHGFM_03728 2.2e-167 kka S Phosphotransferase enzyme family
GPNIHGFM_03729 3.2e-170 P Periplasmic binding protein
GPNIHGFM_03730 1.4e-137 K AraC family transcriptional regulator
GPNIHGFM_03731 3.6e-185 gpr C Aldo/keto reductase family
GPNIHGFM_03732 3.5e-137 bioC_2 Q Methyltransferase domain
GPNIHGFM_03733 1e-86 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPNIHGFM_03734 3e-51 licT K transcriptional antiterminator
GPNIHGFM_03735 1.1e-15 S YhfH-like protein
GPNIHGFM_03736 1e-240 aceA 4.1.3.1 C Isocitrate lyase
GPNIHGFM_03739 5.1e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPNIHGFM_03740 2.3e-58 mhqP S DoxX
GPNIHGFM_03741 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GPNIHGFM_03742 2.5e-138 est 3.1.1.1 S Carboxylesterase
GPNIHGFM_03743 1.7e-136 S COG1647 Esterase lipase
GPNIHGFM_03744 2.3e-176 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNIHGFM_03745 1.2e-27 secG U Preprotein translocase subunit SecG
GPNIHGFM_03746 9.6e-77 yclD
GPNIHGFM_03747 4.5e-264 S Tripartite tricarboxylate transporter TctA family
GPNIHGFM_03748 4.7e-74 S Tripartite tricarboxylate transporter TctB family
GPNIHGFM_03749 9.3e-162 S Tripartite tricarboxylate transporter family receptor
GPNIHGFM_03750 2.5e-222 4.2.1.158 M Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
GPNIHGFM_03751 8e-266 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNIHGFM_03752 2.7e-171 dapAf2 4.3.3.7 EM Dihydrodipicolinate synthetase family
GPNIHGFM_03753 1.5e-116 MA20_15070 K FCD
GPNIHGFM_03754 4.3e-239 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GPNIHGFM_03755 3.9e-295 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
GPNIHGFM_03756 4.1e-133 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPNIHGFM_03757 1.5e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GPNIHGFM_03758 1.5e-186 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPNIHGFM_03759 7.9e-180 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GPNIHGFM_03760 2.7e-202 S response regulator aspartate phosphatase
GPNIHGFM_03762 5.8e-39 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GPNIHGFM_03763 6.7e-235 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
GPNIHGFM_03765 4.5e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GPNIHGFM_03766 2.2e-229 E Peptidase dimerisation domain
GPNIHGFM_03767 3.1e-54 S Domain of unknown function (DUF4870)
GPNIHGFM_03768 1.8e-213 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GPNIHGFM_03769 2.5e-107 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
GPNIHGFM_03770 4.1e-167 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GPNIHGFM_03771 8.7e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
GPNIHGFM_03772 2.4e-37 crh G Phosphocarrier protein Chr
GPNIHGFM_03773 5.4e-178 whiA K May be required for sporulation
GPNIHGFM_03774 4e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GPNIHGFM_03775 5.2e-167 rapZ S Displays ATPase and GTPase activities
GPNIHGFM_03776 1.1e-89 yvcI 3.6.1.55 F Nudix hydrolase
GPNIHGFM_03777 3.8e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GPNIHGFM_03778 3.8e-193 S COG0457 FOG TPR repeat
GPNIHGFM_03779 4.8e-235 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
GPNIHGFM_03780 1.8e-122 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GPNIHGFM_03781 4.6e-107 rhaS5 K AraC-like ligand binding domain
GPNIHGFM_03782 4.9e-126 yobR 2.3.1.1 K FR47-like protein
GPNIHGFM_03783 8.1e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
GPNIHGFM_03784 2.6e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GPNIHGFM_03785 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPNIHGFM_03786 5.5e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPNIHGFM_03787 1e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
GPNIHGFM_03788 2e-225 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPNIHGFM_03789 9e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GPNIHGFM_03790 3.2e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GPNIHGFM_03791 1.2e-238 3.5.1.47 S amidohydrolase
GPNIHGFM_03792 8.2e-132 S Protein of unknown function (DUF3100)
GPNIHGFM_03793 1e-76 S An automated process has identified a potential problem with this gene model
GPNIHGFM_03794 1.7e-36
GPNIHGFM_03795 5.2e-205 ytfP S HI0933-like protein
GPNIHGFM_03796 1.1e-225 yhaA1 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GPNIHGFM_03797 1.2e-67 yugU S Uncharacterised protein family UPF0047
GPNIHGFM_03798 1.7e-162 yvrE G SMP-30/Gluconolaconase/LRE-like region
GPNIHGFM_03799 1e-282 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPNIHGFM_03800 1.5e-195 ftsW D Belongs to the SEDS family
GPNIHGFM_03801 1.9e-209 rodA D Belongs to the SEDS family
GPNIHGFM_03802 1.5e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPNIHGFM_03803 1.5e-30 ytzE K COG1349 Transcriptional regulators of sugar metabolism
GPNIHGFM_03804 6.6e-72 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
GPNIHGFM_03805 8.5e-54 ydaF_2 2.3.1.128 J Acetyltransferases including N-acetylases of ribosomal proteins
GPNIHGFM_03806 1.3e-97 C oxidoreductases (related to aryl-alcohol dehydrogenases)
GPNIHGFM_03807 3.2e-161 ydeE K AraC family transcriptional regulator
GPNIHGFM_03808 1.6e-171 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPNIHGFM_03809 3.2e-106 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GPNIHGFM_03810 2.9e-64 cidA S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
GPNIHGFM_03811 7.3e-100 lrgB M effector of murein hydrolase
GPNIHGFM_03812 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
GPNIHGFM_03813 1.7e-217 1.8.1.4 C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GPNIHGFM_03814 1.4e-175 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GPNIHGFM_03815 4.2e-192 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GPNIHGFM_03816 4.9e-192 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPNIHGFM_03817 6.3e-51 S PFAM Uncharacterised protein family UPF0150
GPNIHGFM_03818 1.8e-125 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_03819 7.5e-163 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
GPNIHGFM_03820 1.1e-152 ytmP 2.7.1.89 M Phosphotransferase
GPNIHGFM_03821 6.3e-14 S YtzH-like protein
GPNIHGFM_03822 6.4e-119 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GPNIHGFM_03823 8.2e-48 ytzB
GPNIHGFM_03824 3.1e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
GPNIHGFM_03825 2e-86 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GPNIHGFM_03826 6.1e-76 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
GPNIHGFM_03827 2.2e-113 S Phosphotransferase system, EIIC
GPNIHGFM_03828 6.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GPNIHGFM_03829 1.3e-145 ytpQ S Belongs to the UPF0354 family
GPNIHGFM_03830 3.6e-103 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPNIHGFM_03831 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
GPNIHGFM_03832 1.9e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GPNIHGFM_03833 3.7e-62 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GPNIHGFM_03834 2.5e-15 XK27_07760 S COG4980 Gas vesicle protein
GPNIHGFM_03835 1.2e-197 aroA 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
GPNIHGFM_03836 6.6e-185 ccpA K catabolite control protein A
GPNIHGFM_03837 1e-231 acuC BQ histone deacetylase
GPNIHGFM_03838 5e-111 acuB S Acetoin utilization protein AcuB
GPNIHGFM_03839 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
GPNIHGFM_03840 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GPNIHGFM_03841 1.3e-71 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
GPNIHGFM_03842 1.3e-116 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
GPNIHGFM_03843 8.5e-160 yvoD P COG0370 Fe2 transport system protein B
GPNIHGFM_03844 7.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPNIHGFM_03845 6.2e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GPNIHGFM_03846 9.3e-48 yvlD S Membrane
GPNIHGFM_03847 8.8e-11 pspC KT positive regulation of macromolecule biosynthetic process
GPNIHGFM_03848 9e-150 yvlB S Putative adhesin
GPNIHGFM_03849 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GPNIHGFM_03850 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GPNIHGFM_03851 7.8e-169 yoaV3 EG EamA-like transporter family
GPNIHGFM_03852 5.5e-201 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPNIHGFM_03853 5.1e-265 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
GPNIHGFM_03854 2.2e-100 D peptidase
GPNIHGFM_03855 2.3e-151 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GPNIHGFM_03856 2.7e-123 ftsE D cell division ATP-binding protein FtsE
GPNIHGFM_03857 3.8e-146 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
GPNIHGFM_03858 2.6e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GPNIHGFM_03859 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GPNIHGFM_03860 1.2e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPNIHGFM_03861 3.8e-30 cspB K cold-shock protein
GPNIHGFM_03862 6.3e-146
GPNIHGFM_03864 6.7e-66 fliS N flagellar protein FliS
GPNIHGFM_03865 1.6e-289 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPNIHGFM_03866 5.7e-47 flaG N flagellar protein FlaG
GPNIHGFM_03867 7.7e-33 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GPNIHGFM_03868 8.2e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GPNIHGFM_03869 1.7e-185 flgL N Belongs to the bacterial flagellin family
GPNIHGFM_03870 2.8e-280 flgK N flagellar hook-associated protein
GPNIHGFM_03872 3.6e-39 N Anti-sigma-28 factor, FlgM
GPNIHGFM_03873 1.7e-75 yvyF S flagellar protein
GPNIHGFM_03874 1.9e-124 comFC S Phosphoribosyl transferase domain
GPNIHGFM_03875 3.7e-249 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GPNIHGFM_03876 1.3e-148 degV S protein conserved in bacteria
GPNIHGFM_03877 2.1e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNIHGFM_03878 4.1e-201 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
GPNIHGFM_03879 2.3e-113 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
GPNIHGFM_03880 4.6e-103 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GPNIHGFM_03881 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
GPNIHGFM_03882 4e-151 oppC EP binding-protein-dependent transport systems inner membrane component
GPNIHGFM_03883 1.2e-172 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_03884 1.8e-146 oppF P Belongs to the ABC transporter superfamily
GPNIHGFM_03885 1.3e-190 oppD P Belongs to the ABC transporter superfamily
GPNIHGFM_03886 3.2e-80 asnC K helix_turn_helix ASNC type
GPNIHGFM_03887 2.4e-182 ywtF K Transcriptional regulator
GPNIHGFM_03888 1.1e-91 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
GPNIHGFM_03889 1.3e-184 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_03890 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPNIHGFM_03891 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPNIHGFM_03892 3e-10 yaaB S Domain of unknown function (DUF370)
GPNIHGFM_03893 4.4e-200 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPNIHGFM_03894 4.5e-32 yaaA S S4 domain
GPNIHGFM_03895 2.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GPNIHGFM_03896 4.5e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPNIHGFM_03897 2.4e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
GPNIHGFM_03898 2.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GPNIHGFM_03899 2.5e-126 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPNIHGFM_03900 1e-108 jag S single-stranded nucleic acid binding R3H
GPNIHGFM_03901 3.3e-245 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPNIHGFM_03902 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GPNIHGFM_03903 1.4e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
GPNIHGFM_03904 8.8e-148 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
GPNIHGFM_03905 1.3e-134 soj D COG1192 ATPases involved in chromosome partitioning
GPNIHGFM_03906 3.9e-151 spo0J K Belongs to the ParB family
GPNIHGFM_03907 1.1e-214 sufS 2.8.1.7, 4.4.1.16 E Aminotransferase class-V
GPNIHGFM_03908 3.6e-114 yyaC S Sporulation protein YyaC
GPNIHGFM_03909 3.6e-180 yyaD S Membrane
GPNIHGFM_03910 1.8e-27 yyzM S protein conserved in bacteria
GPNIHGFM_03911 1e-193 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GPNIHGFM_03912 6.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
GPNIHGFM_03913 4e-57 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GPNIHGFM_03914 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPNIHGFM_03915 1.1e-145 yybS S membrane
GPNIHGFM_03916 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GPNIHGFM_03917 4.2e-53 rplI J binds to the 23S rRNA
GPNIHGFM_03918 2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GPNIHGFM_03919 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPNIHGFM_03925 5.1e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNIHGFM_03926 0.0 vicK 2.7.13.3 T Histidine kinase
GPNIHGFM_03927 2.3e-248 yycH S protein conserved in bacteria
GPNIHGFM_03928 9.2e-156 yycI S protein conserved in bacteria
GPNIHGFM_03929 1.2e-146 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
GPNIHGFM_03930 2.3e-197 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPNIHGFM_03931 3.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPNIHGFM_03932 4.3e-104 spoIVCA L COG1961 Site-specific recombinases, DNA invertase Pin homologs
GPNIHGFM_03933 2e-31 K Helix-turn-helix XRE-family like proteins
GPNIHGFM_03934 1.7e-119
GPNIHGFM_03935 3.4e-74 hsdS2 2.1.1.72 V type I restriction modification DNA specificity domain
GPNIHGFM_03936 1.7e-274 hsdM 2.1.1.72 V Type I restriction-modification system
GPNIHGFM_03937 2.8e-177 S Virulence protein RhuM family
GPNIHGFM_03938 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPNIHGFM_03939 1e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GPNIHGFM_03940 1.2e-190 yttB EGP Major facilitator Superfamily
GPNIHGFM_03942 6.1e-100 ytqB J Putative rRNA methylase
GPNIHGFM_03943 1.7e-105 4.2.1.1 P Reversible hydration of carbon dioxide
GPNIHGFM_03944 3.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
GPNIHGFM_03945 3.4e-65 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPNIHGFM_03946 5.1e-226 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPNIHGFM_03947 1.2e-304 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPNIHGFM_03949 7.3e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
GPNIHGFM_03950 2.2e-179 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GPNIHGFM_03951 6.2e-137 ytlC P ABC transporter
GPNIHGFM_03952 5.5e-136 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GPNIHGFM_03953 3.3e-83 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
GPNIHGFM_03954 1.2e-222 ymfD EGP Major facilitator Superfamily
GPNIHGFM_03955 7.9e-85 ywpF S YwpF-like protein
GPNIHGFM_03957 3e-220 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GPNIHGFM_03958 3.6e-106 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
GPNIHGFM_03959 8.2e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
GPNIHGFM_03960 1.3e-105 mrr V Restriction endonuclease
GPNIHGFM_03961 1.6e-169 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
GPNIHGFM_03962 2.6e-149 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
GPNIHGFM_03963 2.7e-153 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNIHGFM_03964 2.4e-162 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNIHGFM_03965 1.5e-99 pgpB3 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
GPNIHGFM_03966 1.1e-232 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPNIHGFM_03967 1.6e-74 S Putative small multi-drug export protein
GPNIHGFM_03968 1.3e-73 S DinB superfamily
GPNIHGFM_03969 6.4e-58 S Protein of unknown function (DUF1516)
GPNIHGFM_03970 2e-83 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
GPNIHGFM_03971 6.2e-163 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GPNIHGFM_03972 8.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
GPNIHGFM_03973 1.2e-36 yeaO S Protein of unknown function, DUF488
GPNIHGFM_03975 3.3e-19
GPNIHGFM_03976 4.7e-70 yugN S YugN-like family
GPNIHGFM_03977 3.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
GPNIHGFM_03978 2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GPNIHGFM_03979 2.2e-226 yugK C oxidoreductases, Fe-dependent alcohol dehydrogenase family
GPNIHGFM_03980 1.2e-33 yuzA S Domain of unknown function (DUF378)
GPNIHGFM_03981 3.3e-52 J RNA binding protein (contains ribosomal protein S1 domain)
GPNIHGFM_03982 5.3e-201 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
GPNIHGFM_03983 9.2e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPNIHGFM_03984 2.8e-221 yugH 2.6.1.1 E Aminotransferase
GPNIHGFM_03985 1.2e-83 alaR K Transcriptional regulator
GPNIHGFM_03986 5.8e-82 L Transposase IS200 like
GPNIHGFM_03987 1.2e-85 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GPNIHGFM_03988 1.4e-142 yihY S Belongs to the UPF0761 family
GPNIHGFM_03989 1.9e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPNIHGFM_03990 5.6e-226 S antiporter
GPNIHGFM_03991 4.5e-155 S CAAX amino terminal protease family protein
GPNIHGFM_03992 0.0 copA 3.6.3.54 P P-type ATPase
GPNIHGFM_03994 0.0 V ABC transporter (permease)
GPNIHGFM_03995 9.5e-141 yvcR V ABC transporter, ATP-binding protein
GPNIHGFM_03996 8.2e-188 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
GPNIHGFM_03997 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNIHGFM_03998 5e-38 3.1.3.48 GM protein tyrosine phosphatase activity
GPNIHGFM_03999 2.5e-49
GPNIHGFM_04000 8.8e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
GPNIHGFM_04001 1.1e-308 rocB E arginine degradation protein
GPNIHGFM_04002 3.1e-273 mdr EGP Major facilitator Superfamily
GPNIHGFM_04003 1.6e-35 2.6.1.97 S Elongator protein 3, MiaB family, Radical SAM
GPNIHGFM_04004 5.4e-115 C lyase activity
GPNIHGFM_04005 6.7e-41 EGP Major facilitator Superfamily
GPNIHGFM_04009 2e-50 hemN H Involved in the biosynthesis of porphyrin-containing compound
GPNIHGFM_04010 1.1e-167 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GPNIHGFM_04011 3.9e-18 V ABC transporter, ATP-binding protein
GPNIHGFM_04012 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
GPNIHGFM_04013 9.2e-310 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
GPNIHGFM_04014 2.9e-279 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GPNIHGFM_04015 2.9e-210 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPNIHGFM_04016 2e-127 lacR K DeoR C terminal sensor domain
GPNIHGFM_04017 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GPNIHGFM_04018 1.4e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPNIHGFM_04019 6e-230 G ABC transporter substrate-binding protein
GPNIHGFM_04020 9.8e-158 G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_04021 5.8e-155 P PFAM binding-protein-dependent transport systems inner membrane component
GPNIHGFM_04022 2.1e-60 Z012_01525 FJ tRNA wobble adenosine to inosine editing
GPNIHGFM_04023 7.1e-13 S Inner spore coat protein D
GPNIHGFM_04024 1.8e-306 M1-554 G Endonuclease Exonuclease Phosphatase
GPNIHGFM_04025 1.1e-113 S hydrolase
GPNIHGFM_04026 5.1e-19 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GPNIHGFM_04027 8e-266 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
GPNIHGFM_04028 8.5e-266 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPNIHGFM_04029 4.4e-88 S Yip1 domain
GPNIHGFM_04030 2.3e-198 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPNIHGFM_04031 2.4e-97 S Yip1 domain
GPNIHGFM_04032 1e-93 spoVT K stage V sporulation protein
GPNIHGFM_04033 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPNIHGFM_04034 3.1e-39 yabK S Peptide ABC transporter permease
GPNIHGFM_04035 1.4e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GPNIHGFM_04036 1.3e-93 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPNIHGFM_04037 4.5e-169 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPNIHGFM_04038 5.2e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPNIHGFM_04040 1.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
GPNIHGFM_04041 1.6e-61 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
GPNIHGFM_04042 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
GPNIHGFM_04043 3.5e-163 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPNIHGFM_04044 3.3e-25 sspF S DNA topological change
GPNIHGFM_04045 1.2e-39 veg S protein conserved in bacteria
GPNIHGFM_04046 8.4e-162 yabG S peptidase
GPNIHGFM_04047 3.7e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GPNIHGFM_04048 9.7e-101 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPNIHGFM_04049 7e-200 rpfB GH23 T protein conserved in bacteria
GPNIHGFM_04050 1e-147 tatD L hydrolase, TatD
GPNIHGFM_04051 9e-269 S Protein of unknown function (DUF3298)
GPNIHGFM_04052 2.5e-118 T protein histidine kinase activity
GPNIHGFM_04053 5e-277 S ABC transporter
GPNIHGFM_04055 1.3e-182 pelB 4.2.2.2 G Amb_all
GPNIHGFM_04056 9.9e-77 K DNA-binding transcription factor activity
GPNIHGFM_04057 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPNIHGFM_04058 0.0 S Domain of unknown function DUF87
GPNIHGFM_04059 6.7e-173 S NurA
GPNIHGFM_04060 1e-144 yaaC S YaaC-like Protein
GPNIHGFM_04061 7.4e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GPNIHGFM_04062 6.4e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GPNIHGFM_04063 3.9e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPNIHGFM_04064 1.7e-145 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GPNIHGFM_04065 2.3e-309 QT COG2508 Regulator of polyketide synthase expression
GPNIHGFM_04066 2.2e-249 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
GPNIHGFM_04067 1.9e-228 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
GPNIHGFM_04068 3.3e-191 rocG 1.4.1.2, 1.4.1.3 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
GPNIHGFM_04069 1.2e-242 nhaC C Na H antiporter
GPNIHGFM_04070 8.5e-234 eutD 3.4.13.9, 3.5.4.44 E Creatinase/Prolidase N-terminal domain
GPNIHGFM_04071 3.9e-226 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
GPNIHGFM_04072 1.5e-225 amaA 3.5.1.47 E Peptidase dimerisation domain
GPNIHGFM_04073 6.1e-191 hom2 1.1.1.3 E Homoserine dehydrogenase
GPNIHGFM_04074 1.1e-262 gabD_2 1.2.1.9 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNIHGFM_04075 3.2e-61 S Bacterial PH domain
GPNIHGFM_04076 4.7e-143 glnH ET Ligated ion channel L-glutamate- and glycine-binding site
GPNIHGFM_04077 4.2e-110 glnP E Polar amino acid ABC transporter, inner membrane subunit
GPNIHGFM_04078 4.2e-127 glnQ2 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GPNIHGFM_04079 4.9e-190 E Belongs to the ABC transporter superfamily
GPNIHGFM_04080 2.4e-192 oppD P Belongs to the ABC transporter superfamily
GPNIHGFM_04081 5.9e-169 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_04082 3.4e-158 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_04083 5.1e-290 gsiB_4 E COG0747 ABC-type dipeptide transport system, periplasmic component
GPNIHGFM_04084 3e-09
GPNIHGFM_04085 4.3e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GPNIHGFM_04086 3.2e-101 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GPNIHGFM_04087 1.3e-94 K Sigma-70, region 4
GPNIHGFM_04088 8.2e-307 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPNIHGFM_04089 1.8e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPNIHGFM_04090 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPNIHGFM_04091 3.4e-30 S Protein of unknown function (DUF2508)
GPNIHGFM_04092 1.4e-19 bofA S Sigma-K factor-processing regulatory protein BofA
GPNIHGFM_04093 1.1e-149
GPNIHGFM_04094 3.2e-281 E Sodium:solute symporter family
GPNIHGFM_04095 3.5e-23
GPNIHGFM_04096 3.7e-224 2.8.3.16, 2.8.3.20 C acyl-CoA transferases carnitine dehydratase
GPNIHGFM_04097 2.7e-112 K FCD domain
GPNIHGFM_04098 1.3e-157 4.1.3.4, 4.1.3.46 E Hydroxymethylglutaryl-CoA lyase
GPNIHGFM_04099 1.5e-102 gntR K RpiR family transcriptional regulator
GPNIHGFM_04100 5.7e-181 EG COG2610 H gluconate symporter and related permeases
GPNIHGFM_04101 9.1e-127 garR 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
GPNIHGFM_04102 1.1e-187 S Putative nucleotide-binding of sugar-metabolising enzyme
GPNIHGFM_04103 2.6e-222 abgB 3.5.1.47 S amidohydrolase
GPNIHGFM_04104 1.2e-157 metQ M Belongs to the nlpA lipoprotein family
GPNIHGFM_04105 3.3e-113 P COG2011 ABC-type metal ion transport system, permease component
GPNIHGFM_04106 9.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPNIHGFM_04107 2.8e-168 K helix_turn_helix, arabinose operon control protein
GPNIHGFM_04108 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
GPNIHGFM_04109 0.0 aguA 3.2.1.139 G Belongs to the glycosyl hydrolase 67 family
GPNIHGFM_04110 4.3e-175 lplB G Binding-protein-dependent transport system inner membrane component
GPNIHGFM_04111 7.5e-155 lplC G COG0395 ABC-type sugar transport system, permease component
GPNIHGFM_04112 5.1e-306 G Bacterial extracellular solute-binding protein
GPNIHGFM_04113 4.9e-112 S Protein of unknown function, DUF624
GPNIHGFM_04114 5.6e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
GPNIHGFM_04115 6.5e-23 D nuclear chromosome segregation
GPNIHGFM_04117 3.2e-217 hutI Q COG1228 Imidazolonepropionase and related amidohydrolases
GPNIHGFM_04118 3.4e-197 Q COG1228 Imidazolonepropionase and related amidohydrolases
GPNIHGFM_04119 9.8e-302 E COG0747 ABC-type dipeptide transport system, periplasmic component
GPNIHGFM_04120 6e-169 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_04121 1e-151 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNIHGFM_04122 7.8e-166 mviM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
GPNIHGFM_04123 1.3e-28 cspL K 'Cold-shock' DNA-binding domain
GPNIHGFM_04124 8.3e-76 carD K Transcription factor
GPNIHGFM_04125 5.9e-49 arsR K ArsR family transcriptional regulator
GPNIHGFM_04126 4e-65 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNIHGFM_04127 3.3e-53 arsR K transcriptional
GPNIHGFM_04128 1.2e-217 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPNIHGFM_04129 1.9e-74 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
GPNIHGFM_04131 7.6e-235 oxdD 4.1.1.2 G Oxalate decarboxylase
GPNIHGFM_04133 9.5e-161 catE 1.13.11.2 S glyoxalase
GPNIHGFM_04135 5.7e-110 ydhC K FCD
GPNIHGFM_04136 5.1e-198 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
GPNIHGFM_04137 2.5e-64 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNIHGFM_04138 7.8e-118 1.14.12.17 C Oxidoreductase NAD-binding domain
GPNIHGFM_04139 0.0 L ABC transporter
GPNIHGFM_04140 4.3e-73 yndB K Activator of Hsp90 ATPase homolog 1-like protein
GPNIHGFM_04141 9.8e-55 smtB K helix_turn_helix, Arsenical Resistance Operon Repressor
GPNIHGFM_04142 1.7e-63 frataxin S Domain of unknown function (DU1801)
GPNIHGFM_04143 1e-48 azlD E Branched-chain amino acid transport protein (AzlD)
GPNIHGFM_04144 7.9e-126 azlC E AzlC protein
GPNIHGFM_04145 6.2e-73 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNIHGFM_04146 4e-71 phnB5 S 3-demethylubiquinone-9 3-methyltransferase
GPNIHGFM_04147 3.9e-46 GM NmrA-like family
GPNIHGFM_04148 1.2e-230 3.1.3.41, 3.6.1.55 F Belongs to the Nudix hydrolase family
GPNIHGFM_04149 3.5e-67 2.3.1.128 J L-PSP family endoribonuclease
GPNIHGFM_04150 6.3e-154 phzF 5.3.3.17 S Phenazine biosynthesis-like protein
GPNIHGFM_04151 0.0 K transcriptional regulator, MtlR
GPNIHGFM_04152 6.2e-157 4.1.2.13 G Fructose-bisphosphate aldolase class-II
GPNIHGFM_04153 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
GPNIHGFM_04154 7e-161 aadK G Streptomycin adenylyltransferase
GPNIHGFM_04155 8e-94
GPNIHGFM_04157 1.2e-26
GPNIHGFM_04158 7.4e-269 sufB O FeS cluster assembly
GPNIHGFM_04159 5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
GPNIHGFM_04160 1.4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPNIHGFM_04161 1e-243 O assembly protein SufD
GPNIHGFM_04162 1.6e-143 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GPNIHGFM_04163 1.7e-60 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPNIHGFM_04164 7.7e-166 btuF P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
GPNIHGFM_04165 6.1e-94 S Cobalamin adenosyltransferase
GPNIHGFM_04166 1.8e-153 metQ P Belongs to the NlpA lipoprotein family
GPNIHGFM_04167 1.4e-113 metI P COG2011 ABC-type metal ion transport system, permease component
GPNIHGFM_04168 8.3e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPNIHGFM_04169 1.2e-64 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
GPNIHGFM_04170 1.1e-62 arsC 1.20.4.1 P Belongs to the ArsC family
GPNIHGFM_04171 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
GPNIHGFM_04172 1.5e-209 fadA 2.3.1.16 I Belongs to the thiolase family
GPNIHGFM_04173 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
GPNIHGFM_04174 4.6e-214 EGP Major facilitator Superfamily
GPNIHGFM_04175 0.0 S Sugar transport-related sRNA regulator N-term
GPNIHGFM_04176 2.7e-120 S Glycosyltransferase like family
GPNIHGFM_04179 2.4e-107 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPNIHGFM_04181 2.7e-241 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPNIHGFM_04182 9.2e-240 S protein conserved in bacteria
GPNIHGFM_04183 1.3e-55 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNIHGFM_04184 7.3e-77
GPNIHGFM_04185 1.3e-22 EGP Major facilitator Superfamily
GPNIHGFM_04186 1.3e-14 exeA
GPNIHGFM_04188 3e-34
GPNIHGFM_04189 6.5e-66
GPNIHGFM_04190 3.6e-67
GPNIHGFM_04191 6e-137 S GNAT acetyltransferase
GPNIHGFM_04192 1.4e-196 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPNIHGFM_04194 0.0 2.7.13.3 T Histidine kinase
GPNIHGFM_04196 4.5e-85
GPNIHGFM_04197 3.5e-124
GPNIHGFM_04198 4e-116 lolD V ABC transporter
GPNIHGFM_04199 7.4e-300 sdcS P Sodium:sulfate symporter transmembrane region
GPNIHGFM_04200 1.3e-126 T COG4565 Response regulator of citrate malate metabolism
GPNIHGFM_04201 5.5e-292 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GPNIHGFM_04202 1.2e-114 idi I COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GPNIHGFM_04203 7.8e-166 rihB 3.2.2.1 F nucleoside hydrolase
GPNIHGFM_04204 7e-59 S CHY zinc finger
GPNIHGFM_04205 1.8e-224 braB E Component of the transport system for branched-chain amino acids
GPNIHGFM_04209 1.7e-29 sdpI S integral membrane protein
GPNIHGFM_04210 7.6e-217 EGP Major facilitator Superfamily
GPNIHGFM_04211 7.9e-97 GBS0088 S protein conserved in bacteria
GPNIHGFM_04212 2.7e-55 L COG3316 Transposase and inactivated derivatives
GPNIHGFM_04213 2.8e-118 G Tripartite ATP-independent periplasmic transporter, DctM component
GPNIHGFM_04214 2.2e-23 G Tripartite ATP-independent periplasmic transporters, DctQ component
GPNIHGFM_04215 6.6e-86 G Bacterial extracellular solute-binding protein, family 7
GPNIHGFM_04216 2.1e-155 frc 2.8.3.16 C acyl-CoA transferases carnitine dehydratase
GPNIHGFM_04217 9.3e-87 H PFAM pyruvate carboxyltransferase
GPNIHGFM_04218 2.2e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GPNIHGFM_04219 6.4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPNIHGFM_04220 2.7e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPNIHGFM_04221 1.3e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPNIHGFM_04222 7.2e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPNIHGFM_04223 1.1e-147 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
GPNIHGFM_04224 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
GPNIHGFM_04225 9.5e-264 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPNIHGFM_04226 3.3e-172 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPNIHGFM_04227 1.3e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPNIHGFM_04228 6.5e-142 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GPNIHGFM_04229 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPNIHGFM_04230 3.9e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GPNIHGFM_04231 1.8e-262 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GPNIHGFM_04232 1e-173 KLT serine threonine protein kinase
GPNIHGFM_04233 1.8e-128 yabS S protein containing a von Willebrand factor type A (vWA) domain
GPNIHGFM_04234 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
GPNIHGFM_04235 2e-223 citM C Citrate transporter
GPNIHGFM_04237 2.2e-70 yabR J RNA binding protein (contains ribosomal protein S1 domain)
GPNIHGFM_04238 8.2e-61 divIC D Septum formation initiator
GPNIHGFM_04239 2.5e-66 yabQ S spore cortex biosynthesis protein
GPNIHGFM_04240 1.3e-51 yabP S Sporulation protein YabP
GPNIHGFM_04241 1.9e-101 MA20_20865 3.6.1.27 S SNARE associated Golgi protein
GPNIHGFM_04242 1.3e-196 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GPNIHGFM_04243 6.8e-84 2.3.1.128 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNIHGFM_04244 2.1e-174 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPNIHGFM_04245 0.0 S AAA-like domain
GPNIHGFM_04246 5.5e-199 S the current gene model (or a revised gene model) may contain a frame shift
GPNIHGFM_04247 1.1e-157 yddH M Lysozyme-like
GPNIHGFM_04248 7.7e-134 S Conjugative transposon protein TcpC
GPNIHGFM_04249 2.7e-142 blt5 EGP Major facilitator Superfamily
GPNIHGFM_04250 3.5e-34 S Predicted integral membrane protein (DUF2269)
GPNIHGFM_04251 7.4e-192 V penicillin-binding protein
GPNIHGFM_04252 2.8e-40 S Protein of unknown function (DUF4064)
GPNIHGFM_04253 4.2e-77 K Bacterial regulatory proteins, tetR family
GPNIHGFM_04255 6.1e-137 MA20_20400 3.4.11.5 S Alpha/beta hydrolase family
GPNIHGFM_04257 2.1e-110 L PFAM transposase IS4 family protein
GPNIHGFM_04258 2.4e-75 L Transposase
GPNIHGFM_04259 2.1e-103 pksA K BetI-type transcriptional repressor, C-terminal
GPNIHGFM_04260 2.5e-116 S Sap, sulfolipid-1-addressing protein
GPNIHGFM_04261 3.5e-32
GPNIHGFM_04262 3.9e-161 I Acyltransferase family
GPNIHGFM_04263 5.3e-31 phyR K Sigma-70, region 4
GPNIHGFM_04264 3e-31 phyR K Sigma-70, region 4
GPNIHGFM_04265 1.5e-39 S Helix-turn-helix domain
GPNIHGFM_04266 7.2e-146 L Phage integrase, N-terminal SAM-like domain
GPNIHGFM_04267 3.6e-69 S Protein of unknown function (DUF418)
GPNIHGFM_04268 6.2e-88 yqeB
GPNIHGFM_04269 6.5e-81 K Bacterial regulatory proteins, tetR family
GPNIHGFM_04270 2.2e-60 V HNH endonuclease
GPNIHGFM_04271 1.7e-57 S membrane
GPNIHGFM_04272 1.1e-53
GPNIHGFM_04273 5.7e-291 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
GPNIHGFM_04274 2.1e-33
GPNIHGFM_04275 9.9e-92 S DinB superfamily
GPNIHGFM_04276 4.9e-56
GPNIHGFM_04277 3.4e-132 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GPNIHGFM_04278 3.6e-285 malX 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNIHGFM_04279 1.8e-251 4.3.2.2, 5.5.1.2 F Adenylosuccinate lyase C-terminus
GPNIHGFM_04280 7.2e-114 glvR K Helix-turn-helix domain, rpiR family
GPNIHGFM_04281 4.6e-75
GPNIHGFM_04285 5.9e-16
GPNIHGFM_04287 7.4e-253 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
GPNIHGFM_04288 2.2e-134 celG 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
GPNIHGFM_04289 4.9e-246 pagL 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GPNIHGFM_04290 1.1e-124 mngR K UTRA
GPNIHGFM_04291 1.2e-104 S CAAX protease self-immunity
GPNIHGFM_04292 5.4e-174 3.5.1.28 M COG3103 SH3 domain protein
GPNIHGFM_04293 2.6e-58 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
GPNIHGFM_04294 0.0 iucA 6.3.2.38 Q Siderophore biosynthesis protein
GPNIHGFM_04295 0.0 asbB Q IucA / IucC family
GPNIHGFM_04296 2.1e-219 asbC 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
GPNIHGFM_04297 6.5e-41 asbD IQ Phosphopantetheine attachment site
GPNIHGFM_04298 6.9e-181 asbE IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPNIHGFM_04299 1.9e-155 asbF 4.2.1.118 G Xylose isomerase-like TIM barrel
GPNIHGFM_04300 2.2e-96 gmhB 3.1.3.82, 3.1.3.83 E D,D-heptose 1,7-bisphosphate phosphatase
GPNIHGFM_04301 2.7e-244 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
GPNIHGFM_04302 3.3e-146 xth 3.1.11.2 L exodeoxyribonuclease III
GPNIHGFM_04303 2.7e-126 yeeN K transcriptional regulatory protein
GPNIHGFM_04304 1.1e-140 ywfM EG EamA-like transporter family
GPNIHGFM_04306 4.5e-55 yitW S metal-sulfur cluster biosynthetic enzyme
GPNIHGFM_04308 1.3e-276 metP S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GPNIHGFM_04309 1.4e-106 C Zinc-binding dehydrogenase
GPNIHGFM_04310 1.5e-70
GPNIHGFM_04311 1.6e-43
GPNIHGFM_04312 1.4e-210 blt9 EGP Major facilitator Superfamily
GPNIHGFM_04313 4.6e-44
GPNIHGFM_04315 2.3e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
GPNIHGFM_04316 4.4e-109 Q Methyltransferase domain
GPNIHGFM_04317 6.6e-60 gntR1 K helix_turn_helix gluconate operon transcriptional repressor
GPNIHGFM_04318 4.9e-162 V ATPases associated with a variety of cellular activities
GPNIHGFM_04319 6.7e-125
GPNIHGFM_04320 2.3e-151 acrR_2 K Transcriptional regulator
GPNIHGFM_04322 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPNIHGFM_04323 5.7e-29 sspB S spore protein
GPNIHGFM_04324 1.8e-27 sspB S spore protein
GPNIHGFM_04325 7.3e-121 S membrane
GPNIHGFM_04326 1.4e-86 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
GPNIHGFM_04327 5.1e-162 ytlI K LysR substrate binding domain
GPNIHGFM_04328 3.8e-88 ssuE 1.5.1.38 S FMN reductase
GPNIHGFM_04329 1.5e-42 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNIHGFM_04330 1e-162 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNIHGFM_04331 8.8e-54 S Dinitrogenase iron-molybdenum cofactor
GPNIHGFM_04332 4.1e-136 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
GPNIHGFM_04333 1.2e-194 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
GPNIHGFM_04334 1.6e-169 P ABC transporter substrate-binding protein
GPNIHGFM_04335 3.5e-135 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GPNIHGFM_04336 2.3e-204 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
GPNIHGFM_04337 2.4e-11
GPNIHGFM_04338 4.7e-266 cckA 2.7.13.3 T GAF domain
GPNIHGFM_04339 7.4e-256 T Sigma-54 interaction domain
GPNIHGFM_04340 5.6e-197 adhA 1.1.1.1 C alcohol dehydrogenase
GPNIHGFM_04341 6.9e-273 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
GPNIHGFM_04342 1.3e-176 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPNIHGFM_04344 2.8e-263 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
GPNIHGFM_04345 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPNIHGFM_04346 4.1e-53 yaaQ S protein conserved in bacteria
GPNIHGFM_04347 4.8e-182 holB 2.7.7.7 L DNA polymerase III
GPNIHGFM_04348 2.2e-143 yaaT S stage 0 sporulation protein
GPNIHGFM_04349 3e-38 yabA L Involved in initiation control of chromosome replication
GPNIHGFM_04350 4.7e-134 yabB 2.1.1.223 S Conserved hypothetical protein 95
GPNIHGFM_04351 4.2e-40 yazA L endonuclease containing a URI domain
GPNIHGFM_04352 4e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPNIHGFM_04353 1.1e-43 abrB K COG2002 Regulators of stationary sporulation gene expression
GPNIHGFM_04354 5.4e-170 yeaC S COG0714 MoxR-like ATPases
GPNIHGFM_04355 3.9e-207 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
GPNIHGFM_04356 0.0 yebA E COG1305 Transglutaminase-like enzymes
GPNIHGFM_04357 2.1e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GPNIHGFM_04358 1.4e-26 S Domain of unknown function (DUF3173)
GPNIHGFM_04359 1.2e-25 S Helix-turn-helix domain
GPNIHGFM_04360 1.8e-176 T PhoQ Sensor
GPNIHGFM_04361 4.5e-123 T Transcriptional regulatory protein, C terminal
GPNIHGFM_04362 9e-136 V ATPases associated with a variety of cellular activities
GPNIHGFM_04363 0.0 V ABC transporter (permease)
GPNIHGFM_04364 2.7e-198 L Transposase
GPNIHGFM_04365 1.6e-38
GPNIHGFM_04366 2.8e-21 ydcG K Helix-turn-helix domain
GPNIHGFM_04367 2.1e-160 K Acetyltransferase (GNAT) family
GPNIHGFM_04368 2.3e-191 MA20_01110 4.2.1.81 M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
GPNIHGFM_04369 7.2e-134 KT PFAM sigma-54 factor interaction domain-containing protein
GPNIHGFM_04370 1.1e-191 EGP MFS/sugar transport protein
GPNIHGFM_04371 3e-42 S Protein of unknown function (DUF2812)
GPNIHGFM_04372 4.1e-50 padR K Transcriptional regulator PadR-like family
GPNIHGFM_04373 6.7e-56 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
GPNIHGFM_04374 2e-25 K Helix-turn-helix domain
GPNIHGFM_04375 2.7e-74
GPNIHGFM_04376 8.7e-170 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNIHGFM_04377 2.1e-169 K WYL domain
GPNIHGFM_04378 2.4e-110 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GPNIHGFM_04379 9.7e-152 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPNIHGFM_04380 7.3e-148 czcD P COG1230 Co Zn Cd efflux system component
GPNIHGFM_04381 1.3e-48 czrA K transcriptional
GPNIHGFM_04382 7.1e-164 gltC K Transcriptional regulator
GPNIHGFM_04383 1.7e-257 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
GPNIHGFM_04386 4.6e-171 L Endonuclease/Exonuclease/phosphatase family
GPNIHGFM_04387 5.6e-79 K helix_turn_helix, mercury resistance
GPNIHGFM_04388 3.8e-28 aacA-aphD 2.7.1.190 S Protein of unknown function (DUF1679)
GPNIHGFM_04389 7.8e-11 aacA-aphD 2.7.1.190 S Protein of unknown function (DUF1679)
GPNIHGFM_04390 8e-115 O Sap, sulfolipid-1-addressing protein
GPNIHGFM_04391 1.2e-71
GPNIHGFM_04392 4.5e-112 K MerR family transcriptional regulator
GPNIHGFM_04393 2.8e-198 L COG3547 Transposase and inactivated derivatives
GPNIHGFM_04394 4.5e-47 L Transposase
GPNIHGFM_04395 1.6e-204 L Transposase
GPNIHGFM_04397 2.2e-134 L IstB-like ATP binding protein
GPNIHGFM_04398 4.3e-70 L Transposase
GPNIHGFM_04399 1.7e-100 L HTH-like domain
GPNIHGFM_04400 2.6e-35 L Transposase
GPNIHGFM_04405 1.7e-07

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)