ORF_ID e_value Gene_name EC_number CAZy COGs Description
HCLKBIDA_00001 1e-251 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HCLKBIDA_00002 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HCLKBIDA_00003 1.1e-55 nirD 1.7.1.15 P Nitrite reductase
HCLKBIDA_00004 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HCLKBIDA_00005 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCLKBIDA_00006 1.3e-221 nasA P COG2223 Nitrate nitrite transporter
HCLKBIDA_00007 2e-260 M Belongs to the BCCT transporter (TC 2.A.15) family
HCLKBIDA_00009 1.1e-152 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCLKBIDA_00010 1.4e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCLKBIDA_00011 1.3e-67 phaG P Na+/H+ antiporter subunit
HCLKBIDA_00012 3.1e-38 phaF P Multiple resistance and pH regulation protein F (MrpF / PhaF)
HCLKBIDA_00013 2.8e-82 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCLKBIDA_00014 3.9e-268 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCLKBIDA_00015 5.2e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCLKBIDA_00016 8.1e-73 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCLKBIDA_00017 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HCLKBIDA_00018 6.2e-96 yqeG S hydrolase of the HAD superfamily
HCLKBIDA_00019 8.9e-217 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HCLKBIDA_00020 3.6e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCLKBIDA_00021 3e-47 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HCLKBIDA_00022 2.3e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCLKBIDA_00023 3.6e-108 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HCLKBIDA_00024 9.8e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCLKBIDA_00025 6.7e-164 cvfB S protein conserved in bacteria
HCLKBIDA_00026 5.3e-141 cmoA S Methyltransferase domain
HCLKBIDA_00027 7.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCLKBIDA_00028 1.4e-107 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HCLKBIDA_00029 2.5e-109 comEB 3.5.4.12 F ComE operon protein 2
HCLKBIDA_00030 0.0 comEC S Competence protein ComEC
HCLKBIDA_00031 2.4e-07 S YqzM-like protein
HCLKBIDA_00032 4.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
HCLKBIDA_00033 4.8e-36 rpsT J Binds directly to 16S ribosomal RNA
HCLKBIDA_00034 8.4e-207 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HCLKBIDA_00035 5.3e-204 spoIIP M stage II sporulation protein P
HCLKBIDA_00036 2.5e-53
HCLKBIDA_00037 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCLKBIDA_00038 6.2e-221 hemN H Involved in the biosynthesis of porphyrin-containing compound
HCLKBIDA_00039 1.2e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCLKBIDA_00040 1.4e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCLKBIDA_00041 7.8e-295 dnaK O Heat shock 70 kDa protein
HCLKBIDA_00042 4.3e-195 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCLKBIDA_00043 9.3e-175 prmA J Methylates ribosomal protein L11
HCLKBIDA_00044 5e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCLKBIDA_00045 9.9e-255 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HCLKBIDA_00046 6.7e-139 ycgJ_1 Q ubiE/COQ5 methyltransferase family
HCLKBIDA_00047 7.9e-222 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCLKBIDA_00048 1e-114 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HCLKBIDA_00049 1.3e-176 iolS C Aldo keto reductase
HCLKBIDA_00050 6.4e-160 yqeW P COG1283 Na phosphate symporter
HCLKBIDA_00051 2.1e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HCLKBIDA_00052 9.4e-56 yqeY S Yqey-like protein
HCLKBIDA_00053 1.3e-222 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HCLKBIDA_00054 3.4e-98 yqfA S UPF0365 protein
HCLKBIDA_00055 1.6e-73
HCLKBIDA_00056 1.8e-47 yqfC S sporulation protein YqfC
HCLKBIDA_00057 1.5e-222 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HCLKBIDA_00058 6.8e-173 phoH T Phosphate starvation-inducible protein PhoH
HCLKBIDA_00059 0.0 yqfF S membrane-associated HD superfamily hydrolase
HCLKBIDA_00060 5.1e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCLKBIDA_00061 1.3e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HCLKBIDA_00062 1e-72 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HCLKBIDA_00063 1.6e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCLKBIDA_00064 7.1e-18 S YqzL-like protein
HCLKBIDA_00065 1.3e-142 recO L Involved in DNA repair and RecF pathway recombination
HCLKBIDA_00067 2.4e-172 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HCLKBIDA_00068 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HCLKBIDA_00069 2.6e-112 ccpN K CBS domain
HCLKBIDA_00070 1.6e-143 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCLKBIDA_00071 9.5e-80 yaiI S Belongs to the UPF0178 family
HCLKBIDA_00072 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCLKBIDA_00073 1.9e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCLKBIDA_00074 6e-64 C COG2010 Cytochrome c, mono- and diheme variants
HCLKBIDA_00075 2e-138 trmK 2.1.1.217 S SAM-dependent methyltransferase
HCLKBIDA_00076 4.3e-195 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCLKBIDA_00077 2.4e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HCLKBIDA_00078 1.4e-84 carD K Transcription factor
HCLKBIDA_00079 9.3e-49 yqfQ S YqfQ-like protein
HCLKBIDA_00080 8e-252 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCLKBIDA_00081 4e-164 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCLKBIDA_00082 2.5e-08 yqfT S Protein of unknown function (DUF2624)
HCLKBIDA_00083 2.5e-214 pilS 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HCLKBIDA_00084 2.2e-131 GH23 M Transglycosylase SLT domain
HCLKBIDA_00085 1.1e-144 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HCLKBIDA_00086 4e-140 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HCLKBIDA_00087 1.4e-77 zur P Belongs to the Fur family
HCLKBIDA_00088 1.3e-37 S Domain of Unknown Function (DUF1540)
HCLKBIDA_00089 1.7e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HCLKBIDA_00090 6.4e-67 yqfX S membrane
HCLKBIDA_00091 1.2e-200 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HCLKBIDA_00092 3.4e-61 fimV NU translation initiation factor activity
HCLKBIDA_00093 1.7e-186 EGP Major facilitator Superfamily
HCLKBIDA_00094 7.9e-152 ypuA S Secreted protein
HCLKBIDA_00095 2.2e-117 O NfeD-like C-terminal, partner-binding
HCLKBIDA_00096 5.6e-197 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCLKBIDA_00097 2.1e-275 nptA P COG1283 Na phosphate symporter
HCLKBIDA_00102 1.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HCLKBIDA_00103 3.2e-234 yqgE EGP Major facilitator superfamily
HCLKBIDA_00104 0.0 mrdA 3.4.16.4 M penicillin-binding protein
HCLKBIDA_00105 3.1e-78 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCLKBIDA_00106 3.7e-61
HCLKBIDA_00107 1.2e-126 G PFAM Glycoside hydrolase 15-related
HCLKBIDA_00108 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCLKBIDA_00109 1.7e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCLKBIDA_00110 1e-142 S Integral membrane protein DUF92
HCLKBIDA_00111 9.3e-189 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HCLKBIDA_00112 8.4e-241 nhaC C Na H antiporter
HCLKBIDA_00114 5.5e-297 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HCLKBIDA_00115 5.9e-269 spoVAF EG Bacillus/Clostridium GerA spore germination protein
HCLKBIDA_00116 2.1e-67 yueI S Protein of unknown function (DUF1694)
HCLKBIDA_00117 2e-83
HCLKBIDA_00118 3.1e-09 yqgQ S protein conserved in bacteria
HCLKBIDA_00119 6.9e-181 glcK 2.7.1.2 G Glucokinase
HCLKBIDA_00120 2.5e-264 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HCLKBIDA_00121 1.3e-108 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCLKBIDA_00122 4e-27 thiS H ThiS family
HCLKBIDA_00123 1.3e-140 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HCLKBIDA_00124 1e-212 thiO 1.4.3.19 E Glycine oxidase
HCLKBIDA_00125 8.2e-143 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCLKBIDA_00126 1.4e-98
HCLKBIDA_00127 1.2e-194 dglA S Thiamine-binding protein
HCLKBIDA_00128 5.1e-78 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCLKBIDA_00129 4.4e-94 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HCLKBIDA_00130 1.3e-139 yjcH P COG2382 Enterochelin esterase and related enzymes
HCLKBIDA_00131 1.7e-30
HCLKBIDA_00132 1.8e-50 ansR K Helix-turn-helix XRE-family like proteins
HCLKBIDA_00133 7.4e-30 K Cro/C1-type HTH DNA-binding domain
HCLKBIDA_00134 2.3e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCLKBIDA_00135 3.1e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HCLKBIDA_00136 1.9e-92 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCLKBIDA_00137 3.2e-178 pilS 2.7.13.3 F GHKL domain
HCLKBIDA_00138 1.6e-169 yqjA S Putative aromatic acid exporter C-terminal domain
HCLKBIDA_00139 1.2e-94 yqjB S protein conserved in bacteria
HCLKBIDA_00141 2.2e-72 5.1.99.1 E COG0346 Lactoylglutathione lyase and related lyases
HCLKBIDA_00142 2.2e-199 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HCLKBIDA_00145 2.2e-70 yaaR S protein conserved in bacteria
HCLKBIDA_00146 4.5e-82 3.6.1.55 S Pfam Polyketide cyclase dehydrase and lipid transport
HCLKBIDA_00147 2e-74 ykuL S CBS domain
HCLKBIDA_00148 2.7e-41
HCLKBIDA_00149 0.0 apr O Belongs to the peptidase S8 family
HCLKBIDA_00150 8.8e-150 yibQ S protein conserved in bacteria
HCLKBIDA_00151 3.4e-46 tnrA K transcriptional
HCLKBIDA_00152 2.5e-49
HCLKBIDA_00154 1.1e-248 lysC 2.7.2.4 E Belongs to the aspartokinase family
HCLKBIDA_00155 3.3e-125 P Polycystin cation channel
HCLKBIDA_00156 3.7e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCLKBIDA_00157 2.6e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCLKBIDA_00158 5.8e-208 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCLKBIDA_00159 0.0 asnO 6.3.5.4 E Asparagine synthase
HCLKBIDA_00160 3.3e-188 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HCLKBIDA_00161 2.9e-84 V COG4767 Glycopeptide antibiotics resistance protein
HCLKBIDA_00162 6e-54 ybaZ 2.1.1.63 L Methyltransferase
HCLKBIDA_00163 4.5e-97 yvbF K Belongs to the GbsR family
HCLKBIDA_00164 3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HCLKBIDA_00165 6.9e-93 S UPF0316 protein
HCLKBIDA_00166 3.9e-212 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HCLKBIDA_00167 1.8e-142 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCLKBIDA_00168 1.2e-88 CO Thioredoxin-like
HCLKBIDA_00170 1e-93 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HCLKBIDA_00171 5.5e-102 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HCLKBIDA_00172 1.1e-86 fur P Belongs to the Fur family
HCLKBIDA_00173 9.6e-14 S Protein of unknown function (DUF4227)
HCLKBIDA_00174 1.9e-169 xerD L recombinase XerD
HCLKBIDA_00175 2.8e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HCLKBIDA_00176 6.5e-235 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HCLKBIDA_00177 1.8e-69 ohrB O Organic hydroperoxide resistance protein
HCLKBIDA_00178 2.5e-120 yocB J translation release factor activity
HCLKBIDA_00179 1.2e-242 emrB_1 EGP Major facilitator Superfamily
HCLKBIDA_00180 2.8e-20 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HCLKBIDA_00181 3.3e-56
HCLKBIDA_00182 1.7e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HCLKBIDA_00183 5.8e-143 3.5.1.104 G Polysaccharide deacetylase
HCLKBIDA_00184 5.1e-215 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HCLKBIDA_00185 3.9e-54 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HCLKBIDA_00186 4.3e-74 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HCLKBIDA_00187 4.8e-137 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCLKBIDA_00188 2.2e-79 S Pfam:SpoVA
HCLKBIDA_00189 4e-184 spoVAD I Stage V sporulation protein AD
HCLKBIDA_00190 5.1e-57 spoVAEB S Pfam:SpoVA
HCLKBIDA_00191 7.5e-106 spoVAEA S Stage V sporulation protein AE
HCLKBIDA_00192 4.8e-271 spoVAF EG Stage V sporulation protein AF
HCLKBIDA_00193 6.8e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCLKBIDA_00194 1.4e-80 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCLKBIDA_00195 3e-159 ccpC K Transcriptional regulator
HCLKBIDA_00196 1.7e-196 S Psort location CytoplasmicMembrane, score
HCLKBIDA_00197 9.2e-13 L Transposase for insertion sequence element IS1086
HCLKBIDA_00198 6.9e-209 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HCLKBIDA_00199 1.7e-273 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HCLKBIDA_00200 1.8e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HCLKBIDA_00201 1.5e-161 hgd 1.1.1.31, 1.1.1.60 I 3-hydroxyisobutyrate dehydrogenase
HCLKBIDA_00202 1.3e-276 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCLKBIDA_00203 2e-194 echA9 1.1.1.31, 3.1.2.4, 4.2.1.17 I 3-hydroxyisobutyryl-CoA hydrolase
HCLKBIDA_00204 2e-112 ribE 2.5.1.9 H Riboflavin synthase
HCLKBIDA_00205 3e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HCLKBIDA_00206 1.6e-82 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HCLKBIDA_00207 2.6e-85 ypuF S Domain of unknown function (DUF309)
HCLKBIDA_00208 2.7e-126 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCLKBIDA_00209 1.6e-97 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCLKBIDA_00210 8e-105 K Uncharacterized protein conserved in bacteria (DUF2087)
HCLKBIDA_00211 2.7e-296 aldA C Belongs to the aldehyde dehydrogenase family
HCLKBIDA_00212 1.4e-169 sodA 1.15.1.1 P Superoxide dismutase
HCLKBIDA_00213 2.6e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCLKBIDA_00214 1.1e-308 ubiB S ABC1 family
HCLKBIDA_00215 6.8e-45 S ATP synthase, subunit b
HCLKBIDA_00216 4.2e-124 S membrane
HCLKBIDA_00217 7.1e-45 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCLKBIDA_00218 8.1e-79 spoVAC S stage V sporulation protein AC
HCLKBIDA_00219 1.1e-192 spoVAD I Stage V sporulation protein AD
HCLKBIDA_00220 1.2e-55 spoVAE S stage V sporulation protein
HCLKBIDA_00221 4.2e-214 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HCLKBIDA_00222 1.9e-101 spmA S Spore maturation protein
HCLKBIDA_00223 1.4e-74 spmB S Spore maturation protein
HCLKBIDA_00224 3.7e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCLKBIDA_00225 3.7e-96 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HCLKBIDA_00226 3.6e-304 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HCLKBIDA_00227 2e-222 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HCLKBIDA_00228 9e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_00229 0.0 resE 2.7.13.3 T Histidine kinase
HCLKBIDA_00231 1.4e-190 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCLKBIDA_00232 1.1e-141 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HCLKBIDA_00233 1.4e-98 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
HCLKBIDA_00235 2.6e-135 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HCLKBIDA_00236 4.7e-260 nox 1.6.3.4 P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCLKBIDA_00237 8.4e-301 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCLKBIDA_00238 3.9e-43 fer C Ferredoxin
HCLKBIDA_00239 1.6e-188 ypbB 5.1.3.1 S protein conserved in bacteria
HCLKBIDA_00240 4.8e-274 recQ 3.6.4.12 L DNA helicase
HCLKBIDA_00241 6.8e-104 ypbD S metal-dependent membrane protease
HCLKBIDA_00243 3e-08 ypbF S Protein of unknown function (DUF2663)
HCLKBIDA_00244 4.4e-52 K Helix-turn-helix XRE-family like proteins
HCLKBIDA_00245 7e-40 sinR K Helix-turn-helix XRE-family like proteins
HCLKBIDA_00247 1.2e-227 mgs 2.4.1.337 GT4 M Glycosyl Transferase
HCLKBIDA_00248 2.3e-198 cpoA GT4 M Glycosyl transferases group 1
HCLKBIDA_00249 3.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCLKBIDA_00251 5e-226 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HCLKBIDA_00252 2e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
HCLKBIDA_00253 7.9e-171 merR K MerR family transcriptional regulator
HCLKBIDA_00254 1.5e-109 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HCLKBIDA_00255 1.2e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_00256 9.6e-272 T PhoQ Sensor
HCLKBIDA_00257 1.5e-191
HCLKBIDA_00258 5.5e-239 gdhA 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCLKBIDA_00259 1.7e-179 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HCLKBIDA_00260 7.5e-180 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HCLKBIDA_00261 9.1e-113 prsW S Involved in the degradation of specific anti-sigma factors
HCLKBIDA_00262 2.4e-25
HCLKBIDA_00263 8e-210 metB 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
HCLKBIDA_00264 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HCLKBIDA_00265 0.0 metH 2.1.1.13 E Methionine synthase
HCLKBIDA_00266 2e-166 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HCLKBIDA_00267 2.8e-249 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HCLKBIDA_00268 2.4e-131 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HCLKBIDA_00269 2.3e-107 plsC 2.3.1.51, 2.7.4.25 I 1-acyl-sn-glycerol-3-phosphate acyltransferase
HCLKBIDA_00270 3.4e-203 rpsA 1.17.7.4 J Ribosomal protein S1
HCLKBIDA_00271 1.9e-11 yphA
HCLKBIDA_00272 6.1e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HCLKBIDA_00273 1.8e-102 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCLKBIDA_00274 1.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HCLKBIDA_00275 9.4e-40 S Stage VI sporulation protein F
HCLKBIDA_00277 9.4e-135 yphF
HCLKBIDA_00278 2e-280 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HCLKBIDA_00279 7e-101 folE 3.5.4.16 H GTP cyclohydrolase
HCLKBIDA_00280 1.6e-35 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HCLKBIDA_00281 3.3e-58 hepS 2.5.1.30 H heptaprenyl diphosphate synthase
HCLKBIDA_00282 3.3e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HCLKBIDA_00283 3.9e-159 ubiA 2.5.1.39 H UbiA prenyltransferase family
HCLKBIDA_00284 3.7e-162 mqnA 1.21.98.1, 4.2.1.151 S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HCLKBIDA_00285 8.6e-184 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCLKBIDA_00286 1.4e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HCLKBIDA_00287 4.1e-144 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HCLKBIDA_00288 1.1e-220 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HCLKBIDA_00289 1.5e-197 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HCLKBIDA_00290 1.6e-58 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HCLKBIDA_00291 5.1e-284 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCLKBIDA_00292 1.5e-186 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCLKBIDA_00293 2.3e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HCLKBIDA_00294 1.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HCLKBIDA_00295 7.3e-225 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCLKBIDA_00296 7e-147 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCLKBIDA_00297 3.4e-208 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HCLKBIDA_00298 1.1e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HCLKBIDA_00299 1.8e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCLKBIDA_00300 1.9e-231 S COG0457 FOG TPR repeat
HCLKBIDA_00301 1.2e-97 ypiB S Belongs to the UPF0302 family
HCLKBIDA_00302 4.6e-82 ypiF S Protein of unknown function (DUF2487)
HCLKBIDA_00303 7.4e-91 qcrA C Menaquinol-cytochrome c reductase
HCLKBIDA_00304 7.7e-123 petB C COG1290 Cytochrome b subunit of the bc complex
HCLKBIDA_00305 4.2e-149 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HCLKBIDA_00306 3.1e-110 ypjA S membrane
HCLKBIDA_00307 2.7e-140 S Sporulation protein YpjB (SpoYpjB)
HCLKBIDA_00308 1e-117 yugP S Zn-dependent protease
HCLKBIDA_00309 1.1e-212 tcaB EGP Major facilitator Superfamily
HCLKBIDA_00310 9.6e-158 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HCLKBIDA_00311 2.9e-60 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HCLKBIDA_00312 1.7e-145 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCLKBIDA_00313 5e-75 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HCLKBIDA_00314 2.8e-85 M Acetyltransferase (GNAT) domain
HCLKBIDA_00315 4.5e-238 rtcB 6.5.1.3 S tRNA-splicing ligase RtcB
HCLKBIDA_00316 1.4e-37
HCLKBIDA_00317 9.4e-74 yjcF S Acetyltransferase (GNAT) domain
HCLKBIDA_00318 5.7e-143 Q Methyltransferase domain
HCLKBIDA_00319 1.2e-51
HCLKBIDA_00321 1.2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCLKBIDA_00322 1.7e-96 S Protein of unknown function (DUF1706)
HCLKBIDA_00323 1.5e-269 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCLKBIDA_00324 2.3e-133 yodH Q Methyltransferase
HCLKBIDA_00325 6.8e-137 M 3D domain
HCLKBIDA_00326 6.8e-174 M 3D domain
HCLKBIDA_00328 1.9e-158 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCLKBIDA_00329 5.3e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HCLKBIDA_00330 3.2e-152 ysaA S HAD-hyrolase-like
HCLKBIDA_00331 1.8e-102 ykoE S ABC-type cobalt transport system, permease component
HCLKBIDA_00332 4.4e-280 ykoD 3.6.3.24 P ABC transporter
HCLKBIDA_00333 2.1e-143 ykoC P Cobalt transport protein
HCLKBIDA_00334 2.9e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HCLKBIDA_00335 4e-107 yvdD_1 3.2.2.10 S Belongs to the LOG family
HCLKBIDA_00336 1.3e-88 lytE2 M COG1388 FOG LysM repeat
HCLKBIDA_00337 6.6e-234 els S Acetyltransferase
HCLKBIDA_00338 3.1e-104 yvdT K Transcriptional regulator
HCLKBIDA_00339 2.1e-185 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCLKBIDA_00340 4.7e-137 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HCLKBIDA_00341 1.3e-187 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCLKBIDA_00342 1.4e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HCLKBIDA_00343 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
HCLKBIDA_00344 1.3e-57 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HCLKBIDA_00345 0.0 iucA 6.3.2.38 Q Siderophore biosynthesis protein
HCLKBIDA_00346 0.0 asbB Q IucA / IucC family
HCLKBIDA_00347 1.9e-236 asbC 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HCLKBIDA_00348 3.8e-41 asbD IQ Phosphopantetheine attachment site
HCLKBIDA_00349 1.1e-189 asbE IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCLKBIDA_00350 8e-162 asbF 4.2.1.118 G Xylose isomerase-like TIM barrel
HCLKBIDA_00351 1.4e-98 gmhB 3.1.3.82, 3.1.3.83 E D,D-heptose 1,7-bisphosphate phosphatase
HCLKBIDA_00352 4.7e-249 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HCLKBIDA_00353 1.2e-154 xth 3.1.11.2 L exodeoxyribonuclease III
HCLKBIDA_00354 7.9e-126 yeeN K transcriptional regulatory protein
HCLKBIDA_00356 6.5e-146 ywfM EG EamA-like transporter family
HCLKBIDA_00358 5.3e-56 yitW S metal-sulfur cluster biosynthetic enzyme
HCLKBIDA_00360 1.8e-281 metP S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HCLKBIDA_00361 6.8e-161 ydeE K AraC family transcriptional regulator
HCLKBIDA_00362 1.1e-97 padR K Virulence activator alpha C-term
HCLKBIDA_00363 2.3e-86 S Domain of unknown function (DUF4188)
HCLKBIDA_00364 1.4e-215 blt9 EGP Major facilitator Superfamily
HCLKBIDA_00365 1.5e-140
HCLKBIDA_00366 2.2e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HCLKBIDA_00367 3.2e-53
HCLKBIDA_00368 5.9e-10 yxlE S Phospholipase_D-nuclease N-terminal
HCLKBIDA_00369 8.7e-170 yxlF V ABC transporter, ATP-binding protein
HCLKBIDA_00370 3.6e-140 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HCLKBIDA_00371 2.8e-96 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HCLKBIDA_00372 6.7e-07 S Family of unknown function (DUF5345)
HCLKBIDA_00373 1.2e-08 mutT 3.6.1.55 F NUDIX domain
HCLKBIDA_00374 1.8e-186 3.4.11.5 I Alpha beta hydrolase
HCLKBIDA_00375 8.4e-73 S Bacterial PH domain
HCLKBIDA_00376 5.1e-23 CP_0264 3.2.2.10 S Belongs to the LOG family
HCLKBIDA_00377 2.8e-88 C HEAT repeats
HCLKBIDA_00378 4.6e-125 catB 2.3.1.28 V This enzyme is an effector of chloramphenicol resistance in bacteria
HCLKBIDA_00379 2.3e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HCLKBIDA_00380 4e-36 K COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit
HCLKBIDA_00381 4.8e-107 S Golgi phosphoprotein 3 (GPP34)
HCLKBIDA_00382 1.7e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HCLKBIDA_00383 5.8e-141 motA N flagellar motor
HCLKBIDA_00384 2e-135 motB N Flagellar motor protein
HCLKBIDA_00385 7.4e-203 ytvI S sporulation integral membrane protein YtvI
HCLKBIDA_00386 4.8e-88 dksA T general stress protein
HCLKBIDA_00387 1.4e-59 S Uncharacterized protein conserved in bacteria (DUF2200)
HCLKBIDA_00388 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCLKBIDA_00389 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCLKBIDA_00390 1.9e-71 yccU S CoA-binding protein
HCLKBIDA_00391 5.5e-289 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
HCLKBIDA_00392 6.4e-193 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HCLKBIDA_00393 9.6e-149 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_00394 2.8e-100 IV02_12955 U MarC family integral membrane protein
HCLKBIDA_00395 3.8e-295 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HCLKBIDA_00396 1.5e-52 S Belongs to the HesB IscA family
HCLKBIDA_00397 2.5e-95 Q ubiE/COQ5 methyltransferase family
HCLKBIDA_00398 1.6e-219 G Transmembrane secretion effector
HCLKBIDA_00400 7.8e-21 S Protein of unknown function (DUF2564)
HCLKBIDA_00401 5e-295 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Belongs to the FGGY kinase family
HCLKBIDA_00402 1.8e-52
HCLKBIDA_00403 4.7e-69 S Src homology 3 domains
HCLKBIDA_00404 1.8e-273 P Spore gernimation protein GerA
HCLKBIDA_00405 1.4e-201 E Spore germination protein
HCLKBIDA_00406 2.7e-202 S Spore germination B3/ GerAC like, C-terminal
HCLKBIDA_00411 1.2e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HCLKBIDA_00412 2.9e-48 comGC U Required for transformation and DNA binding
HCLKBIDA_00413 2.6e-74 mshD NU general secretion pathway protein
HCLKBIDA_00415 1.4e-80
HCLKBIDA_00418 2e-36 yqgY S Protein of unknown function (DUF2626)
HCLKBIDA_00419 3e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HCLKBIDA_00420 6.6e-08 S Protein of unknown function (DUF2759)
HCLKBIDA_00421 1e-153 yqhG S Bacterial protein YqhG of unknown function
HCLKBIDA_00422 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HCLKBIDA_00423 7e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HCLKBIDA_00424 2.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HCLKBIDA_00425 5.4e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HCLKBIDA_00426 3.9e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HCLKBIDA_00427 9.5e-155 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HCLKBIDA_00428 0.0 helD 3.6.4.12 L DNA helicase
HCLKBIDA_00429 8.5e-159 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HCLKBIDA_00430 9.1e-200 splB 4.1.99.14 L Spore photoproduct lyase
HCLKBIDA_00431 1e-75 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HCLKBIDA_00432 3.6e-168 yqhO S esterase of the alpha-beta hydrolase superfamily
HCLKBIDA_00433 2.7e-59
HCLKBIDA_00434 1.8e-89 yqhR S Conserved membrane protein YqhR
HCLKBIDA_00435 2e-194 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HCLKBIDA_00436 3.2e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCLKBIDA_00437 1.1e-98 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HCLKBIDA_00438 1e-50 S YfzA-like protein
HCLKBIDA_00439 1.3e-35 yqhV S Protein of unknown function (DUF2619)
HCLKBIDA_00440 3.4e-169 spoIIIAA S stage III sporulation protein AA
HCLKBIDA_00441 1.1e-84 spoIIIAB S Stage III sporulation protein
HCLKBIDA_00442 4.4e-29 spoIIIAC S stage III sporulation protein AC
HCLKBIDA_00443 1.6e-40 spoIIIAD S Stage III sporulation protein AD
HCLKBIDA_00444 3.8e-205 spoIIIAE S stage III sporulation protein AE
HCLKBIDA_00445 3.9e-94 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HCLKBIDA_00446 6.4e-114 spoIIIAG S stage III sporulation protein AG
HCLKBIDA_00447 5.4e-90 spoIIIAH S SpoIIIAH-like protein
HCLKBIDA_00448 1.1e-56
HCLKBIDA_00449 2.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCLKBIDA_00450 2.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HCLKBIDA_00451 3.1e-66 yqhY S protein conserved in bacteria
HCLKBIDA_00452 5.5e-68 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCLKBIDA_00453 1.5e-253 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCLKBIDA_00454 9.7e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCLKBIDA_00455 3.3e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCLKBIDA_00456 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCLKBIDA_00457 3.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HCLKBIDA_00458 4.6e-79 argR K Regulates arginine biosynthesis genes
HCLKBIDA_00459 6.1e-294 recN L May be involved in recombinational repair of damaged DNA
HCLKBIDA_00460 6.1e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HCLKBIDA_00461 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HCLKBIDA_00463 1.7e-118 2.7.8.33, 2.7.8.35 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCLKBIDA_00464 9.4e-36 yqzF S Protein of unknown function (DUF2627)
HCLKBIDA_00465 0.0 bkdR KT Transcriptional regulator
HCLKBIDA_00466 1.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCLKBIDA_00467 8.3e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCLKBIDA_00468 1e-187 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCLKBIDA_00469 5.7e-183 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCLKBIDA_00470 5.7e-228 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCLKBIDA_00471 2.9e-75 yqiW S Belongs to the UPF0403 family
HCLKBIDA_00472 7.1e-60
HCLKBIDA_00474 1.5e-146 ykrA S hydrolases of the HAD superfamily
HCLKBIDA_00475 1e-30
HCLKBIDA_00476 2e-46 csoR S transcriptional
HCLKBIDA_00477 3.8e-28 copP P Heavy-metal-associated domain
HCLKBIDA_00478 1.4e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
HCLKBIDA_00480 1.8e-192 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HCLKBIDA_00481 8.7e-218 E Peptidase family M28
HCLKBIDA_00482 3.4e-112 GM NmrA-like family
HCLKBIDA_00483 2e-184 ytvI S AI-2E family transporter
HCLKBIDA_00484 4.3e-98 copC S CopC domain
HCLKBIDA_00485 4.4e-200 yhdY M Mechanosensitive ion channel
HCLKBIDA_00486 1.8e-192 T Metal dependent phosphohydrolases with conserved 'HD' motif.
HCLKBIDA_00487 6e-147 S Membrane transport protein
HCLKBIDA_00488 7.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCLKBIDA_00489 2.5e-228 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HCLKBIDA_00490 1.3e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCLKBIDA_00491 2.4e-37 ykuS S Belongs to the UPF0180 family
HCLKBIDA_00492 2.7e-135 ykuT M Mechanosensitive ion channel
HCLKBIDA_00493 4.7e-102 ykuU O Alkyl hydroperoxide reductase
HCLKBIDA_00494 8.2e-84 ykuV CO thiol-disulfide
HCLKBIDA_00495 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
HCLKBIDA_00496 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCLKBIDA_00497 2.4e-30 ykzG S Belongs to the UPF0356 family
HCLKBIDA_00498 3e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCLKBIDA_00499 5.3e-17 S Protein of unknown function (Tiny_TM_bacill)
HCLKBIDA_00500 3.3e-70 recN L Putative cell-wall binding lipoprotein
HCLKBIDA_00501 1.3e-201 bkdA1 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCLKBIDA_00502 1.7e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCLKBIDA_00503 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCLKBIDA_00504 2.2e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HCLKBIDA_00505 1.8e-187 oppD P Belongs to the ABC transporter superfamily
HCLKBIDA_00506 5e-187 E Belongs to the ABC transporter superfamily
HCLKBIDA_00507 0.0 appA_2 E COG0747 ABC-type dipeptide transport system, periplasmic component
HCLKBIDA_00508 4.7e-174 P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_00509 2.3e-162 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_00510 4.1e-68 CO cell redox homeostasis
HCLKBIDA_00511 8.4e-280 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HCLKBIDA_00512 6.6e-124 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
HCLKBIDA_00513 1e-230 legA 3.5.1.2 O Peptidase family M48
HCLKBIDA_00514 7.5e-280 speA 4.1.1.19 E Arginine
HCLKBIDA_00515 1.1e-40 yktA S Belongs to the UPF0223 family
HCLKBIDA_00516 3.5e-117 yktB S Belongs to the UPF0637 family
HCLKBIDA_00517 3.5e-154 suhB 3.1.3.25 G Inositol monophosphatase
HCLKBIDA_00518 1.1e-164 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HCLKBIDA_00520 0.0 typA T GTP-binding protein TypA
HCLKBIDA_00521 7.2e-53 ylaH S YlaH-like protein
HCLKBIDA_00522 3.2e-32 ylaI S protein conserved in bacteria
HCLKBIDA_00523 2.7e-252 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HCLKBIDA_00524 5.7e-94 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HCLKBIDA_00525 9e-41 ylaN S Belongs to the UPF0358 family
HCLKBIDA_00526 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HCLKBIDA_00527 4.1e-159 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HCLKBIDA_00528 5.9e-199 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HCLKBIDA_00529 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HCLKBIDA_00530 9.7e-104 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HCLKBIDA_00531 1.1e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HCLKBIDA_00532 8.8e-93 yozB S membrane
HCLKBIDA_00533 4.6e-85
HCLKBIDA_00534 9.5e-64 ylbA S YugN-like family
HCLKBIDA_00535 9.5e-214 ylbC S protein with SCP PR1 domains
HCLKBIDA_00536 1.3e-84 yiiD Q protein, possibly involved in aromatic compounds catabolism
HCLKBIDA_00537 3.5e-73 ylbD S Putative coat protein
HCLKBIDA_00538 1.6e-31 ylbE S YlbE-like protein
HCLKBIDA_00539 5e-142 rimK1 HJ Prokaryotic glutathione synthetase, ATP-grasp domain
HCLKBIDA_00540 7.9e-60 ylbF S Belongs to the UPF0342 family
HCLKBIDA_00541 1.1e-46 ylbG S UPF0298 protein
HCLKBIDA_00542 4.1e-65 S Methylthioribose kinase
HCLKBIDA_00543 9.8e-100 rsmD 2.1.1.171 L Methyltransferase
HCLKBIDA_00544 7.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCLKBIDA_00545 2.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
HCLKBIDA_00546 4e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
HCLKBIDA_00547 3.4e-194 ylbL T Belongs to the peptidase S16 family
HCLKBIDA_00548 2.4e-231 ylbM S Belongs to the UPF0348 family
HCLKBIDA_00549 4.4e-94 yceD S metal-binding, possibly nucleic acid-binding protein
HCLKBIDA_00550 1.3e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HCLKBIDA_00551 3.6e-62 S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HCLKBIDA_00552 5.2e-92 ylbP K n-acetyltransferase
HCLKBIDA_00553 2.9e-146 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCLKBIDA_00554 1e-10 S Protein of unknown function (DUF3397)
HCLKBIDA_00555 1.9e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HCLKBIDA_00556 2.6e-79 mraZ K Belongs to the MraZ family
HCLKBIDA_00557 4.8e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCLKBIDA_00558 6e-47 ftsL D cell division protein FtsL
HCLKBIDA_00559 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HCLKBIDA_00561 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HCLKBIDA_00562 1e-273 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCLKBIDA_00563 3.5e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCLKBIDA_00564 2.5e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCLKBIDA_00565 7.4e-250 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCLKBIDA_00566 2.3e-185 spoVE D Belongs to the SEDS family
HCLKBIDA_00567 8.5e-126 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCLKBIDA_00569 8.1e-222 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCLKBIDA_00570 4.1e-185 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCLKBIDA_00571 5e-162 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HCLKBIDA_00572 1.1e-124 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCLKBIDA_00573 2.1e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCLKBIDA_00574 3.4e-46 ylmC S sporulation protein
HCLKBIDA_00575 2.5e-147 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HCLKBIDA_00576 2.4e-119 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HCLKBIDA_00577 3.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCLKBIDA_00578 2e-43 yggT S membrane
HCLKBIDA_00579 6.6e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HCLKBIDA_00580 4.8e-64 divIVA D Cell division initiation protein
HCLKBIDA_00581 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCLKBIDA_00582 5.5e-115 dksA T COG1734 DnaK suppressor protein
HCLKBIDA_00583 1.8e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCLKBIDA_00584 2.9e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCLKBIDA_00585 3.2e-104 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCLKBIDA_00586 1.1e-231 pyrP F Xanthine uracil
HCLKBIDA_00587 2.2e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HCLKBIDA_00588 1e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCLKBIDA_00589 2.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCLKBIDA_00590 0.0 carB 6.3.5.5 F Belongs to the CarB family
HCLKBIDA_00591 1.5e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HCLKBIDA_00592 7.4e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCLKBIDA_00593 1.1e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCLKBIDA_00594 2.2e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCLKBIDA_00595 2.6e-118 Q ubiE/COQ5 methyltransferase family
HCLKBIDA_00597 0.0 yfhO S Bacterial membrane protein YfhO
HCLKBIDA_00598 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HCLKBIDA_00599 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HCLKBIDA_00600 3.5e-39 ylzA S Belongs to the UPF0296 family
HCLKBIDA_00601 3.7e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HCLKBIDA_00602 9.2e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCLKBIDA_00603 2.5e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCLKBIDA_00604 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCLKBIDA_00605 2.2e-168 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCLKBIDA_00606 4.8e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCLKBIDA_00607 9.1e-131 stp 3.1.3.16 T phosphatase
HCLKBIDA_00608 0.0 KLT serine threonine protein kinase
HCLKBIDA_00609 2.1e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCLKBIDA_00610 2.7e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HCLKBIDA_00612 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HCLKBIDA_00613 1.5e-59 asp S protein conserved in bacteria
HCLKBIDA_00614 2.8e-307 yloV S kinase related to dihydroxyacetone kinase
HCLKBIDA_00615 1.5e-150 degV3 S protein conserved in bacteria
HCLKBIDA_00616 3.2e-121 sdaAB 4.3.1.17 E L-serine dehydratase
HCLKBIDA_00617 7.7e-147 sdaAA 4.3.1.17 E L-serine dehydratase
HCLKBIDA_00618 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCLKBIDA_00619 1.3e-97 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HCLKBIDA_00620 1.1e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCLKBIDA_00621 4.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HCLKBIDA_00622 2.3e-128 IQ reductase
HCLKBIDA_00623 5.4e-31 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCLKBIDA_00624 4.4e-138 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCLKBIDA_00625 3.2e-09 yfkK S Belongs to the UPF0435 family
HCLKBIDA_00626 0.0 smc D Required for chromosome condensation and partitioning
HCLKBIDA_00627 2.6e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCLKBIDA_00628 2.3e-51 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCLKBIDA_00629 1.1e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCLKBIDA_00630 6.4e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HCLKBIDA_00631 2.5e-33 ylqC S Belongs to the UPF0109 family
HCLKBIDA_00632 9e-69 ylqD S YlqD protein
HCLKBIDA_00633 4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCLKBIDA_00634 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HCLKBIDA_00635 0.0 argS 6.1.1.19 J Arginyl tRNA synthetase N terminal dom
HCLKBIDA_00636 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCLKBIDA_00638 4.3e-103 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HCLKBIDA_00639 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCLKBIDA_00640 3.4e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCLKBIDA_00641 1e-07 lig1
HCLKBIDA_00642 1.3e-79 ylqH S FlhB HrpN YscU SpaS Family
HCLKBIDA_00643 4e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HCLKBIDA_00644 9.7e-169 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HCLKBIDA_00645 1.3e-172 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HCLKBIDA_00646 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCLKBIDA_00647 7.2e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HCLKBIDA_00648 4e-167 xerC L tyrosine recombinase XerC
HCLKBIDA_00649 1.4e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCLKBIDA_00650 2.4e-227 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCLKBIDA_00651 4.1e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HCLKBIDA_00652 1.7e-66 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HCLKBIDA_00653 8.8e-75 flgC N Belongs to the flagella basal body rod proteins family
HCLKBIDA_00654 1.7e-42 fliE N Flagellar hook-basal body
HCLKBIDA_00655 3.4e-246 fliF N The M ring may be actively involved in energy transduction
HCLKBIDA_00656 1.5e-175 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HCLKBIDA_00657 1.1e-77 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HCLKBIDA_00658 2e-247 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HCLKBIDA_00659 8.2e-65 fliJ N bacterial-type flagellum organization
HCLKBIDA_00661 1.6e-264 N Flagellar hook-length control protein FliK
HCLKBIDA_00662 6.2e-73 flgD N Flagellar basal body rod modification protein
HCLKBIDA_00663 1.6e-146 flgG N Flagellar basal body rod
HCLKBIDA_00664 6.7e-28 flbD N protein, possibly involved in motility
HCLKBIDA_00665 6.3e-70 fliL N Controls the rotational direction of flagella during chemotaxis
HCLKBIDA_00666 3.6e-177 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HCLKBIDA_00667 2.2e-213 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HCLKBIDA_00668 4.2e-59 cheY T cheY-homologous receiver domain
HCLKBIDA_00669 1.4e-108 fliZ N Flagellar biosynthesis protein, FliO
HCLKBIDA_00670 9.6e-113 fliP N Plays a role in the flagellum-specific transport system
HCLKBIDA_00671 3.6e-39 fliQ N Role in flagellar biosynthesis
HCLKBIDA_00672 2.8e-132 fliR N Flagellar biosynthetic protein FliR
HCLKBIDA_00673 3.7e-191 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HCLKBIDA_00674 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HCLKBIDA_00675 3.1e-181 flhF N Flagellar biosynthesis regulator FlhF
HCLKBIDA_00676 1.1e-96
HCLKBIDA_00677 1.2e-171 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HCLKBIDA_00678 8.3e-108 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HCLKBIDA_00679 8.6e-84 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HCLKBIDA_00680 4.9e-134 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCLKBIDA_00682 5.2e-133 rpsB J Belongs to the universal ribosomal protein uS2 family
HCLKBIDA_00683 4.4e-150 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCLKBIDA_00684 1.3e-123 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HCLKBIDA_00685 7.1e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCLKBIDA_00686 9.7e-146 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCLKBIDA_00687 1.6e-130 cdsA 2.7.7.41 S Belongs to the CDS family
HCLKBIDA_00688 1.3e-207 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HCLKBIDA_00689 3.4e-225 rasP M zinc metalloprotease
HCLKBIDA_00690 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCLKBIDA_00691 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCLKBIDA_00692 5.6e-80 rimP S Required for maturation of 30S ribosomal subunits
HCLKBIDA_00693 5.2e-201 nusA K Participates in both transcription termination and antitermination
HCLKBIDA_00694 9.4e-43 ylxR K nucleic-acid-binding protein implicated in transcription termination
HCLKBIDA_00695 1.9e-47 ylxQ J ribosomal protein
HCLKBIDA_00696 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCLKBIDA_00697 2.3e-41 ylxP S protein conserved in bacteria
HCLKBIDA_00698 1.9e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCLKBIDA_00699 1.5e-174 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCLKBIDA_00700 5e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HCLKBIDA_00701 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCLKBIDA_00702 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HCLKBIDA_00703 9.8e-191 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HCLKBIDA_00704 2e-225 pepR S Belongs to the peptidase M16 family
HCLKBIDA_00705 3.3e-36 ymxH S YlmC YmxH family
HCLKBIDA_00706 6.1e-160 spoVFA E subunit a
HCLKBIDA_00707 6.7e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HCLKBIDA_00708 3.6e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCLKBIDA_00709 2.5e-220 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HCLKBIDA_00710 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCLKBIDA_00711 4.6e-311 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCLKBIDA_00712 3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HCLKBIDA_00713 1.9e-09 S YlzJ-like protein
HCLKBIDA_00714 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HCLKBIDA_00715 4.5e-129 ymfC K Transcriptional regulator
HCLKBIDA_00716 3.6e-238 ymfF S Peptidase M16
HCLKBIDA_00717 1.3e-248 ymfH S zinc protease
HCLKBIDA_00718 8.7e-125 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_00719 5.1e-40 ymfJ S Protein of unknown function (DUF3243)
HCLKBIDA_00720 4.6e-140 ymfK S Protein of unknown function (DUF3388)
HCLKBIDA_00721 4.7e-128 ymfM S protein conserved in bacteria
HCLKBIDA_00722 8.7e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCLKBIDA_00723 5.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
HCLKBIDA_00724 1e-290 deaD 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCLKBIDA_00725 2.3e-190 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCLKBIDA_00726 7.7e-188 L Calcineurin-like phosphoesterase superfamily domain
HCLKBIDA_00727 5.1e-265 sbcC L AAA domain
HCLKBIDA_00729 4e-116 L DNA recombination
HCLKBIDA_00730 1.8e-218 rny S Endoribonuclease that initiates mRNA decay
HCLKBIDA_00731 3.4e-154 ymdB S protein conserved in bacteria
HCLKBIDA_00732 6.7e-38 spoVS S Stage V sporulation protein S
HCLKBIDA_00733 7e-155 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HCLKBIDA_00734 4e-303 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HCLKBIDA_00735 8.9e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HCLKBIDA_00736 2.6e-103 cotE S Spore coat protein
HCLKBIDA_00737 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCLKBIDA_00738 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCLKBIDA_00739 4.7e-140 J Putative SAM-dependent methyltransferase
HCLKBIDA_00740 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCLKBIDA_00741 2.7e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HCLKBIDA_00742 2.9e-190 xerD L Belongs to the 'phage' integrase family
HCLKBIDA_00743 1.3e-168 spoVK O stage V sporulation protein K
HCLKBIDA_00744 2.9e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HCLKBIDA_00745 2.1e-265 glnA 6.3.1.2 E glutamine synthetase
HCLKBIDA_00746 1.3e-75 M Acetyltransferase (GNAT) domain
HCLKBIDA_00747 6.1e-249 glcE C FAD binding domain
HCLKBIDA_00748 6.7e-267 glcF C Glycolate oxidase
HCLKBIDA_00749 1.1e-280 glcD 1.1.2.4, 1.1.3.15 C FAD linked oxidases, C-terminal domain
HCLKBIDA_00750 0.0 glcB 2.3.3.9 C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HCLKBIDA_00751 7.6e-143 Q Domain of unknown function (DUF2437)
HCLKBIDA_00752 1.2e-137 K helix_turn_helix isocitrate lyase regulation
HCLKBIDA_00753 6.7e-90
HCLKBIDA_00754 4e-98 MA20_21960 FG Domain of unknown function (DUF4269)
HCLKBIDA_00755 4.2e-214 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCLKBIDA_00757 3.2e-220 yuxJ EGP Major facilitator Superfamily
HCLKBIDA_00758 2.6e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCLKBIDA_00760 6.6e-119 yneB L resolvase
HCLKBIDA_00761 4.2e-34 ynzC S UPF0291 protein
HCLKBIDA_00762 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCLKBIDA_00763 4.2e-74 yneE S Sporulation inhibitor of replication protein sirA
HCLKBIDA_00764 7.9e-29 yneF S UPF0154 protein
HCLKBIDA_00765 0.0 mdlA V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCLKBIDA_00766 0.0 mdlB V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCLKBIDA_00767 3.9e-81 yneK S Protein of unknown function (DUF2621)
HCLKBIDA_00768 4.9e-13
HCLKBIDA_00770 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HCLKBIDA_00771 1.4e-246 gerAA EG Spore germination protein
HCLKBIDA_00772 3.1e-193 gerAB E Spore germination protein
HCLKBIDA_00773 5.1e-212 gerAC S Spore germination B3/ GerAC like, C-terminal
HCLKBIDA_00774 3.7e-183 S response regulator aspartate phosphatase
HCLKBIDA_00777 4.4e-150 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HCLKBIDA_00778 1.2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HCLKBIDA_00779 1e-111 cpsE M Bacterial sugar transferase
HCLKBIDA_00780 1.3e-83 wzxA S Polysaccharide biosynthesis protein
HCLKBIDA_00781 8.9e-63 M TupA-like ATPgrasp
HCLKBIDA_00782 9e-71 M Glycosyl transferases group 1
HCLKBIDA_00783 1.4e-19
HCLKBIDA_00784 4e-81 M Glycosyl transferases group 1
HCLKBIDA_00785 1.9e-150 wcnD M Glycosyl Transferase
HCLKBIDA_00786 1.4e-208 manC 2.7.7.13, 5.3.1.8 G mannose-1-phosphate guanylyltransferase
HCLKBIDA_00787 8.6e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCLKBIDA_00788 4.6e-106 D AAA domain
HCLKBIDA_00789 1.4e-22 K Cro/C1-type HTH DNA-binding domain
HCLKBIDA_00791 1.2e-111 K intracellular protease amidase
HCLKBIDA_00792 1.1e-106 1.6.5.2 S NADPH-dependent FMN reductase
HCLKBIDA_00793 9.7e-70 ytcD5 K Transcriptional regulator
HCLKBIDA_00796 5.1e-311 S LXG domain of WXG superfamily
HCLKBIDA_00801 8.8e-268 ydbT S Bacterial PH domain
HCLKBIDA_00802 1.9e-86 S Bacterial PH domain
HCLKBIDA_00803 2.2e-140 S CAAX protease self-immunity
HCLKBIDA_00804 6.5e-251 celF 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HCLKBIDA_00805 3.2e-44
HCLKBIDA_00806 2.5e-223 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCLKBIDA_00807 4.7e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCLKBIDA_00808 8.8e-51 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HCLKBIDA_00809 2.1e-210 ybhE S Bacterial protein of unknown function (DUF871)
HCLKBIDA_00810 8.6e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HCLKBIDA_00811 5.6e-166 K Transcriptional regulator
HCLKBIDA_00813 1.4e-292 E Bacterial extracellular solute-binding proteins, family 5 Middle
HCLKBIDA_00814 4.5e-158 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_00815 4.1e-167 EP N-terminal TM domain of oligopeptide transport permease C
HCLKBIDA_00816 5.5e-186 oppD P Belongs to the ABC transporter superfamily
HCLKBIDA_00817 5.2e-195 E Belongs to the ABC transporter superfamily
HCLKBIDA_00818 5.1e-226 E Peptidase family M28
HCLKBIDA_00819 1.1e-254 P Sodium:sulfate symporter transmembrane region
HCLKBIDA_00820 2.5e-225 3.5.1.47 S Peptidase dimerisation domain
HCLKBIDA_00821 3.3e-225 3.5.1.47 S Peptidase dimerisation domain
HCLKBIDA_00822 2.6e-86
HCLKBIDA_00824 5.5e-189 P Bacterial extracellular solute-binding protein
HCLKBIDA_00825 6.7e-201 fbpC2 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCLKBIDA_00826 9.6e-292 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_00827 8.1e-307 2.7.13.3 T Histidine kinase
HCLKBIDA_00828 8.6e-139 T helix_turn_helix, arabinose operon control protein
HCLKBIDA_00829 1.1e-203 S response regulator aspartate phosphatase
HCLKBIDA_00830 1e-128 puuD 4.1.3.27 S Peptidase C26
HCLKBIDA_00831 2.3e-151 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCLKBIDA_00832 3.6e-194 T PhoQ Sensor
HCLKBIDA_00833 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_00834 1.6e-166 V ABC transporter, ATP-binding protein
HCLKBIDA_00835 1.1e-122 S ABC-2 family transporter protein
HCLKBIDA_00836 1.1e-100 S Putative adhesin
HCLKBIDA_00837 1.3e-34
HCLKBIDA_00839 6.3e-73
HCLKBIDA_00840 4.1e-30 S response regulator aspartate phosphatase
HCLKBIDA_00841 2.1e-208 S Protein of unknown function (DUF418)
HCLKBIDA_00842 9.7e-158 K Transcriptional regulator
HCLKBIDA_00843 6.1e-165 S Belongs to the pirin family
HCLKBIDA_00844 3.1e-59 hxlR K HxlR-like helix-turn-helix
HCLKBIDA_00845 4.3e-250 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HCLKBIDA_00846 1.3e-170 aadK G Streptomycin adenylyltransferase
HCLKBIDA_00847 1.4e-175 cat P Catalase
HCLKBIDA_00848 2.8e-41 S Protein of unknown function (DUF2642)
HCLKBIDA_00851 9.1e-206 S response regulator aspartate phosphatase
HCLKBIDA_00852 1.3e-134 K Transcriptional regulator
HCLKBIDA_00853 1.8e-192 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HCLKBIDA_00854 8.3e-85 dctQ1 G Tripartite ATP-independent periplasmic transporters, DctQ component
HCLKBIDA_00855 3.9e-219 siaT_2 G Tripartite ATP-independent periplasmic transporter, DctM component
HCLKBIDA_00856 3.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
HCLKBIDA_00857 1.5e-91 S DNA-binding protein with PD1-like DNA-binding motif
HCLKBIDA_00858 1.9e-283 MA20_41335 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCLKBIDA_00859 5.2e-204 2.3.1.16, 2.3.1.9 I Thiolase, C-terminal domain
HCLKBIDA_00860 4.9e-56 S DUF35 OB-fold domain, acyl-CoA-associated
HCLKBIDA_00861 3.9e-237 yoaB EGP Major facilitator Superfamily
HCLKBIDA_00862 1.4e-211 1.1.1.14 E Dehydrogenase
HCLKBIDA_00863 7.9e-118 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_00864 2.3e-134 K DeoR C terminal sensor domain
HCLKBIDA_00865 9.4e-80 rpiB 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
HCLKBIDA_00866 1.8e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HCLKBIDA_00867 3e-113 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dak2
HCLKBIDA_00868 3.2e-175 glpX 2.2.1.1, 3.1.3.11, 3.1.3.37 G Bacterial fructose-1,6-bisphosphatase, glpX-encoded
HCLKBIDA_00869 7.6e-166 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
HCLKBIDA_00870 9.3e-178 S Tripartite tricarboxylate transporter family receptor
HCLKBIDA_00872 5.2e-265 S Tripartite tricarboxylate transporter TctA family
HCLKBIDA_00873 6.9e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCLKBIDA_00874 1.4e-181 K Periplasmic binding protein domain
HCLKBIDA_00875 9.6e-80 yiaB S yiaA/B two helix domain
HCLKBIDA_00877 1e-266 yeaV M Belongs to the BCCT transporter (TC 2.A.15) family
HCLKBIDA_00879 3.7e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HCLKBIDA_00881 8.3e-265 G beta-fructofuranosidase activity
HCLKBIDA_00882 1e-136 T helix_turn_helix, arabinose operon control protein
HCLKBIDA_00883 0.0 2.7.13.3 T Histidine kinase
HCLKBIDA_00884 1.6e-246 G Bacterial extracellular solute-binding protein
HCLKBIDA_00885 8e-171 U Binding-protein-dependent transport system inner membrane component
HCLKBIDA_00886 4.5e-149 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_00887 4.7e-260 C FAD dependent oxidoreductase
HCLKBIDA_00889 1.2e-252 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HCLKBIDA_00890 5.7e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCLKBIDA_00891 1.9e-138 glvR K Helix-turn-helix domain, rpiR family
HCLKBIDA_00892 8.4e-79 S Protein of unknown function (DUF1648)
HCLKBIDA_00893 3.3e-80
HCLKBIDA_00894 1.1e-08
HCLKBIDA_00895 1.2e-91 S Protein of unknown function with HXXEE motif
HCLKBIDA_00896 3.3e-180 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HCLKBIDA_00897 5.6e-141 K COG1349 Transcriptional regulators of sugar metabolism
HCLKBIDA_00898 1.7e-79 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCLKBIDA_00899 1e-41 gatB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
HCLKBIDA_00900 5.9e-239 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
HCLKBIDA_00901 6.3e-196 gatD 1.1.1.14, 1.1.1.251 C Alcohol dehydrogenase GroES-like domain
HCLKBIDA_00902 1.5e-155 kbaY 4.1.2.13, 4.1.2.40 G in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
HCLKBIDA_00903 9.3e-235 M cell wall anchor domain
HCLKBIDA_00904 3e-102 3.4.22.70 M Sortase family
HCLKBIDA_00905 1.3e-54 K Helix-turn-helix XRE-family like proteins
HCLKBIDA_00908 0.0 msbA2 3.6.3.44 V ABC transporter
HCLKBIDA_00909 9.3e-172 XK27_06795 K sequence-specific DNA binding
HCLKBIDA_00911 0.0 spaB S Lantibiotic dehydratase, C terminus
HCLKBIDA_00912 8.4e-262 spaC1 V Lanthionine synthetase C-like protein
HCLKBIDA_00913 3.4e-103 4.1.1.36, 6.3.2.5 H Flavoprotein
HCLKBIDA_00914 2.7e-129 V AAA domain, putative AbiEii toxin, Type IV TA system
HCLKBIDA_00915 1.1e-55 S ABC-2 family transporter protein
HCLKBIDA_00916 3.6e-132
HCLKBIDA_00917 1.8e-124 T Transcriptional regulatory protein, C terminal
HCLKBIDA_00918 9.2e-251 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HCLKBIDA_00919 6.6e-39 comEA L Helix-hairpin-helix motif
HCLKBIDA_00920 5.5e-102 2.7.7.7 L Domain of unknown function (DUF4357)
HCLKBIDA_00921 5.7e-31
HCLKBIDA_00922 3.5e-26 K Cro/C1-type HTH DNA-binding domain
HCLKBIDA_00923 1.3e-40 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HCLKBIDA_00924 3e-31 fic S Fic/DOC family
HCLKBIDA_00927 1e-173 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HCLKBIDA_00928 2.8e-182 rbsR K transcriptional
HCLKBIDA_00929 1.4e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCLKBIDA_00930 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCLKBIDA_00931 2.7e-277 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HCLKBIDA_00932 1.7e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
HCLKBIDA_00933 6.9e-162 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HCLKBIDA_00934 5.7e-77
HCLKBIDA_00935 1.8e-71 K Transcriptional regulator
HCLKBIDA_00936 6e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCLKBIDA_00937 6e-61 K MerR, DNA binding
HCLKBIDA_00938 5.8e-108
HCLKBIDA_00939 0.0
HCLKBIDA_00940 6.5e-54
HCLKBIDA_00941 1e-181 S Choline/ethanolamine kinase
HCLKBIDA_00942 2.2e-90 ykuD S protein conserved in bacteria
HCLKBIDA_00943 4.7e-232 S Erythromycin esterase
HCLKBIDA_00944 4.2e-158 NT chemotaxis protein
HCLKBIDA_00945 5.7e-256 putP E Sodium:solute symporter family
HCLKBIDA_00946 2.6e-191 3.5.3.6 E Amidinotransferase
HCLKBIDA_00947 5e-184 K Transcriptional regulator
HCLKBIDA_00948 4.4e-155 V ABC transporter
HCLKBIDA_00949 1.3e-111 S ABC-2 family transporter protein
HCLKBIDA_00950 1.3e-148 K Transcriptional regulator
HCLKBIDA_00951 1.9e-150 yxxF EG EamA-like transporter family
HCLKBIDA_00952 1e-75
HCLKBIDA_00953 3.8e-212 dapE 3.5.1.18 E Peptidase dimerisation domain
HCLKBIDA_00954 1.5e-202 6.3.5.5 S ATP-grasp domain
HCLKBIDA_00955 2.4e-69 K helix_turn_helix, mercury resistance
HCLKBIDA_00956 1e-57 S Domain of unknown function (DUF4260)
HCLKBIDA_00957 7.1e-158 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylases
HCLKBIDA_00959 1.6e-102 3.5.1.124 S DJ-1/PfpI family
HCLKBIDA_00960 6.7e-156 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HCLKBIDA_00961 1.7e-208 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
HCLKBIDA_00962 8.4e-45 ptxB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
HCLKBIDA_00963 6.4e-182 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCLKBIDA_00964 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HCLKBIDA_00966 7.3e-64 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCLKBIDA_00967 2.3e-270 S Chlorophyllase enzyme
HCLKBIDA_00968 2.3e-145 G COG0395 ABC-type sugar transport system, permease component
HCLKBIDA_00969 4.2e-121 msmF3 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_00970 1.6e-235 msmE7 G Bacterial extracellular solute-binding protein
HCLKBIDA_00971 1.2e-135 bceA V ABC transporter, ATP-binding protein
HCLKBIDA_00972 0.0 bceB V ABC transporter (permease)
HCLKBIDA_00973 2.8e-57 gerKC S Spore germination B3/ GerAC like, C-terminal
HCLKBIDA_00974 1.6e-129 gerKC S Spore germination B3/ GerAC like, C-terminal
HCLKBIDA_00975 1e-54 gerKB E Spore germination protein
HCLKBIDA_00976 1.1e-119 gerKB E Spore germination protein
HCLKBIDA_00977 3.6e-255 gerKA EG Spore germination protein
HCLKBIDA_00978 2.1e-197
HCLKBIDA_00979 9.5e-180 ectD 1.14.11.55 Q Phytanoyl-CoA dioxygenase (PhyH)
HCLKBIDA_00981 7.5e-299 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HCLKBIDA_00982 2.5e-175 feuA P Iron-uptake system-binding protein
HCLKBIDA_00983 2e-183 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCLKBIDA_00984 1.1e-184 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCLKBIDA_00985 6.2e-159 besA S Putative esterase
HCLKBIDA_00986 2.1e-241 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HCLKBIDA_00987 4.8e-120 tcpP 2.7.11.1 KT Forkhead associated domain
HCLKBIDA_00988 4.7e-154 3.5.2.6 V beta-lactamase
HCLKBIDA_00989 1.7e-132 S Nucleotidyltransferase domain
HCLKBIDA_00990 1e-243 hemAT NT chemotaxis protein
HCLKBIDA_00991 2.8e-188 K helix_turn _helix lactose operon repressor
HCLKBIDA_00992 2.5e-155 dkgB S Aldo/keto reductase family
HCLKBIDA_00993 1.8e-181 fhuD P ABC transporter
HCLKBIDA_00994 2.4e-144 K Helix-turn-helix domain
HCLKBIDA_00995 7.2e-59 S Ketosteroid isomerase-related protein
HCLKBIDA_00996 2.7e-188 MA20_22185 K Transcriptional regulator, LacI family
HCLKBIDA_00997 6e-185 S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_00998 2.1e-235 cycB_1 G Bacterial extracellular solute-binding protein
HCLKBIDA_00999 7.8e-166 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01000 1.3e-143 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01001 3.8e-192 G Xylose isomerase
HCLKBIDA_01002 7.3e-156 S Membrane transport protein
HCLKBIDA_01004 4.5e-96 K response regulator
HCLKBIDA_01005 5.8e-59
HCLKBIDA_01006 2.5e-20
HCLKBIDA_01007 3.3e-86 M1-1022 1.8.5.2 S DoxX
HCLKBIDA_01008 6.3e-271 murE 6.3.2.13 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCLKBIDA_01009 2.4e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HCLKBIDA_01010 9.2e-104 K Bacterial regulatory proteins, tetR family
HCLKBIDA_01011 6.7e-122 yqeB
HCLKBIDA_01012 4.2e-46 K PadR family transcriptional regulator
HCLKBIDA_01013 2.8e-73 V (ABC) transporter
HCLKBIDA_01014 1e-162 V VanW like protein
HCLKBIDA_01016 2.5e-123 yoqW S Belongs to the SOS response-associated peptidase family
HCLKBIDA_01017 1e-176 isp O Belongs to the peptidase S8 family
HCLKBIDA_01018 4.2e-162 yjlA EG Putative multidrug resistance efflux transporter
HCLKBIDA_01019 3.8e-255
HCLKBIDA_01020 8.7e-199 sstT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCLKBIDA_01021 0.0 pepF E oligoendopeptidase
HCLKBIDA_01022 0.0 clpE O Belongs to the ClpA ClpB family
HCLKBIDA_01023 1e-81 cwlM 3.5.1.28 M COG3103 SH3 domain protein
HCLKBIDA_01024 4e-47
HCLKBIDA_01025 5.6e-294 K Mga helix-turn-helix domain
HCLKBIDA_01028 2.6e-66 S YolD-like protein
HCLKBIDA_01029 1.3e-221 P Protein of unknown function (DUF418)
HCLKBIDA_01030 1.8e-226 GK ROK family
HCLKBIDA_01031 1.1e-242 cycB_2 G Bacterial extracellular solute-binding protein
HCLKBIDA_01032 4.1e-170 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01033 2.1e-146 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01034 7.2e-189 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_01035 1.6e-188 S Oxidoreductase family, NAD-binding Rossmann fold
HCLKBIDA_01036 5e-156 5.1.3.22, 5.3.1.5 G Xylose isomerase-like TIM barrel
HCLKBIDA_01037 9.9e-182 S Alpha/beta hydrolase family
HCLKBIDA_01038 1.4e-153 K LysR substrate binding domain
HCLKBIDA_01039 2.6e-122 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HCLKBIDA_01040 4.6e-230 EGP Major facilitator Superfamily
HCLKBIDA_01041 3e-249 EGP Major facilitator Superfamily
HCLKBIDA_01042 2.2e-111 K Bacterial transcriptional repressor C-terminal
HCLKBIDA_01043 8.1e-148 2.1.1.144, 2.1.1.197 S Methyltransferase domain
HCLKBIDA_01044 2.6e-224 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HCLKBIDA_01045 1.7e-171 fhuD P Periplasmic binding protein
HCLKBIDA_01046 1.4e-173 fhuG 3.6.3.34 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCLKBIDA_01047 8.1e-54 isdG 1.14.99.48, 1.14.99.57 C Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
HCLKBIDA_01048 1.3e-112 isdC M NEAr Transporter domain
HCLKBIDA_01049 0.0 M Cell surface protein
HCLKBIDA_01050 7.9e-163 isdE P ABC transporter substrate-binding protein
HCLKBIDA_01051 1.7e-171 fhuB11 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCLKBIDA_01052 4.8e-137 fhuC 3.6.3.28, 3.6.3.34 HP ABC transporter, ATP-binding protein
HCLKBIDA_01053 6.5e-142 srtB 3.4.22.70 S Sortase family
HCLKBIDA_01054 1.1e-242 yhdP S COG1253 Hemolysins and related proteins containing CBS domains
HCLKBIDA_01055 7e-161 opuAC E Glycine betaine ABC transporter
HCLKBIDA_01056 2.1e-260 S Predicted membrane protein (DUF2254)
HCLKBIDA_01057 6.8e-175 P Catalase
HCLKBIDA_01060 1.4e-74 S LXG domain of WXG superfamily
HCLKBIDA_01061 4.3e-16
HCLKBIDA_01062 1.7e-39
HCLKBIDA_01063 2.8e-170 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HCLKBIDA_01064 1.1e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HCLKBIDA_01066 1e-137 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HCLKBIDA_01067 3.9e-113 Q Methyltransferase domain
HCLKBIDA_01068 1.3e-60 gntR1 K helix_turn_helix gluconate operon transcriptional repressor
HCLKBIDA_01069 1.8e-164 V ATPases associated with a variety of cellular activities
HCLKBIDA_01070 1.5e-129
HCLKBIDA_01071 3.6e-157 acrR_2 K Transcriptional regulator
HCLKBIDA_01073 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HCLKBIDA_01074 5.7e-29 sspB S spore protein
HCLKBIDA_01075 1.8e-27 sspB S spore protein
HCLKBIDA_01076 1.1e-121 S membrane
HCLKBIDA_01077 4.6e-87 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HCLKBIDA_01078 5.4e-164 ytlI K LysR substrate binding domain
HCLKBIDA_01079 1.3e-38 yvrI K RNA polymerase
HCLKBIDA_01080 2.6e-109 dedA 3.1.3.1 S SNARE associated Golgi protein
HCLKBIDA_01081 9.9e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HCLKBIDA_01082 1.3e-170 agpT K AraC-like ligand binding domain
HCLKBIDA_01083 9.4e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HCLKBIDA_01084 1.9e-206 desK 2.7.13.3 T Histidine kinase
HCLKBIDA_01085 9e-107 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCLKBIDA_01086 5.6e-189 mgtE P Acts as a magnesium transporter
HCLKBIDA_01087 4.6e-76 K transcriptional
HCLKBIDA_01088 5.5e-56
HCLKBIDA_01089 2.5e-89 3.1.1.29 K -acetyltransferase
HCLKBIDA_01090 8e-246 aspT EK Alanine-glyoxylate amino-transferase
HCLKBIDA_01091 2e-82 yvbK 3.1.3.25 K acetyltransferase
HCLKBIDA_01092 2.8e-145 map 3.4.11.18 E Methionine aminopeptidase
HCLKBIDA_01093 4.2e-80 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HCLKBIDA_01094 9.2e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HCLKBIDA_01095 5.7e-200 cdaR KT Sugar diacid utilization regulator
HCLKBIDA_01096 1.9e-189 yetN S Protein of unknown function (DUF3900)
HCLKBIDA_01097 3.2e-120
HCLKBIDA_01098 5e-116 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCLKBIDA_01099 1.6e-185 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HCLKBIDA_01100 6.4e-156 hisJ3 3.1.3.15 E PHP domain
HCLKBIDA_01101 2.2e-97 yocH 3.5.1.28 M 3D domain
HCLKBIDA_01102 2e-215 2.3.1.157, 2.7.7.23 JM Bacterial transferase hexapeptide (six repeats)
HCLKBIDA_01103 4.5e-129 K transcriptional
HCLKBIDA_01104 1.7e-139 S carbohydrate derivative metabolic process
HCLKBIDA_01106 1.2e-249 I radical SAM domain protein
HCLKBIDA_01107 7.5e-285 H Involved in the biosynthesis of porphyrin-containing compound
HCLKBIDA_01108 1.8e-10
HCLKBIDA_01109 2.5e-138 yafE Q methyltransferase
HCLKBIDA_01110 6.9e-14 1.2.7.12 S Uncharacterised protein family UPF0066
HCLKBIDA_01111 2.3e-89 1.2.7.12 S Uncharacterised protein family UPF0066
HCLKBIDA_01112 1.9e-223 EGP Major facilitator Superfamily
HCLKBIDA_01113 1e-101 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCLKBIDA_01114 1.9e-172 wbpP 5.1.3.2, 5.1.3.7 M GDP-mannose 4,6 dehydratase
HCLKBIDA_01115 8e-129 M Glycosyl transferases group 1
HCLKBIDA_01116 1.9e-102
HCLKBIDA_01117 1.2e-102 GT2,GT4 M transferase activity, transferring glycosyl groups
HCLKBIDA_01118 7e-119 M transferase activity, transferring glycosyl groups
HCLKBIDA_01119 2e-113 M Glycosyl transferase family 2
HCLKBIDA_01120 6e-236 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCLKBIDA_01121 1.9e-35 VPA1573 J acetyltransferase
HCLKBIDA_01122 1.5e-247 M Glycosyltransferase like family 2
HCLKBIDA_01123 2.4e-41 S Protein of unknown function (DUF2642)
HCLKBIDA_01124 4.5e-26
HCLKBIDA_01125 1.1e-242 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HCLKBIDA_01126 1.5e-112 ycsK E anatomical structure formation involved in morphogenesis
HCLKBIDA_01127 1.5e-130 K helix_turn_helix isocitrate lyase regulation
HCLKBIDA_01128 1.6e-174 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HCLKBIDA_01129 2.4e-110 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HCLKBIDA_01130 2e-227 dgoD 4.2.1.6 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HCLKBIDA_01131 3.4e-157 S Metallo-beta-lactamase superfamily
HCLKBIDA_01132 1.5e-88 S Predicted membrane protein (DUF2243)
HCLKBIDA_01133 6.1e-122 S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
HCLKBIDA_01134 7.2e-242 T COG0642 Signal transduction histidine kinase
HCLKBIDA_01135 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_01136 1.7e-190 4.2.1.103 K DJ-1/PfpI family
HCLKBIDA_01137 1.8e-113 S Predicted membrane protein (DUF2306)
HCLKBIDA_01138 2e-208 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HCLKBIDA_01139 3.6e-76 S VanZ like family
HCLKBIDA_01140 8.1e-111 wrbA 1.6.5.2 S Belongs to the WrbA family
HCLKBIDA_01141 4.1e-92 2.3.1.128 K Acetyltransferase (GNAT) family
HCLKBIDA_01142 1.3e-129 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HCLKBIDA_01143 0.0 V SNF2 family N-terminal domain
HCLKBIDA_01144 2.4e-12 S Domain of unknown function (DUF5082)
HCLKBIDA_01145 2.5e-08 S Family of unknown function (DUF5344)
HCLKBIDA_01146 2.3e-255 S LXG domain of WXG superfamily
HCLKBIDA_01147 4.3e-112
HCLKBIDA_01148 4.3e-96
HCLKBIDA_01149 2.5e-149
HCLKBIDA_01150 3.4e-283 E Sodium:solute symporter family
HCLKBIDA_01151 4.6e-23
HCLKBIDA_01152 4.9e-229 2.8.3.16, 2.8.3.20 C acyl-CoA transferases carnitine dehydratase
HCLKBIDA_01153 5.2e-116 K FCD domain
HCLKBIDA_01154 1.8e-164 4.1.3.4, 4.1.3.46 E Hydroxymethylglutaryl-CoA lyase
HCLKBIDA_01155 6.6e-213 1.4.1.9 G Transmembrane secretion effector
HCLKBIDA_01157 4.2e-102 gntR K RpiR family transcriptional regulator
HCLKBIDA_01158 4.3e-181 EG COG2610 H gluconate symporter and related permeases
HCLKBIDA_01159 9.1e-127 garR 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HCLKBIDA_01160 1.5e-187 S Putative nucleotide-binding of sugar-metabolising enzyme
HCLKBIDA_01161 4.8e-224 abgB 3.5.1.47 S amidohydrolase
HCLKBIDA_01162 1.2e-157 metQ M Belongs to the nlpA lipoprotein family
HCLKBIDA_01163 3.3e-113 P COG2011 ABC-type metal ion transport system, permease component
HCLKBIDA_01164 3.3e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCLKBIDA_01165 1.4e-167 K helix_turn_helix, arabinose operon control protein
HCLKBIDA_01167 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HCLKBIDA_01168 0.0 aguA 3.2.1.139 G Belongs to the glycosyl hydrolase 67 family
HCLKBIDA_01169 3.9e-176 lplB G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01170 1.7e-154 lplC G COG0395 ABC-type sugar transport system, permease component
HCLKBIDA_01171 0.0 G Bacterial extracellular solute-binding protein
HCLKBIDA_01172 4e-122 S Protein of unknown function, DUF624
HCLKBIDA_01173 6.8e-201 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HCLKBIDA_01174 4.4e-21 D nuclear chromosome segregation
HCLKBIDA_01176 1.4e-220 hutI Q COG1228 Imidazolonepropionase and related amidohydrolases
HCLKBIDA_01177 2.2e-204 Q COG1228 Imidazolonepropionase and related amidohydrolases
HCLKBIDA_01178 1.9e-305 E COG0747 ABC-type dipeptide transport system, periplasmic component
HCLKBIDA_01179 9.9e-172 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_01180 3.5e-155 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_01181 7.6e-191 oppD P Belongs to the ABC transporter superfamily
HCLKBIDA_01182 1.6e-188 ddpF E Belongs to the ABC transporter superfamily
HCLKBIDA_01183 5e-176 S Protein of unknown function (DUF1177)
HCLKBIDA_01184 1.3e-243 3.5.1.18 E Acetylornithine deacetylase
HCLKBIDA_01185 3.6e-137 K Transcriptional regulator
HCLKBIDA_01186 2.6e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HCLKBIDA_01187 7.6e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G xylulose kinase
HCLKBIDA_01188 9.5e-205 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
HCLKBIDA_01189 1.1e-220 xylR GK ROK family
HCLKBIDA_01190 6.1e-125 MA20_14010 S Trehalose utilisation
HCLKBIDA_01191 1.8e-223 yrbE S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_01192 1.6e-285 KT PucR C-terminal helix-turn-helix domain
HCLKBIDA_01193 4.2e-110 hyuE 5.1.99.3 E Asp/Glu/Hydantoin racemase
HCLKBIDA_01194 2.6e-286 S OPT oligopeptide transporter protein
HCLKBIDA_01195 5.3e-187 S Protein of unknown function (DUF917)
HCLKBIDA_01196 1.3e-163 S Protein of unknown function (DUF1177)
HCLKBIDA_01197 3.2e-113 aroM E AroM protein
HCLKBIDA_01198 1.7e-176 E Thermophilic metalloprotease (M29)
HCLKBIDA_01199 1.3e-216 EGP Major facilitator Superfamily
HCLKBIDA_01200 3.1e-30 dmpI 5.3.2.6 S Tautomerase enzyme
HCLKBIDA_01201 2.6e-214 chrA P chromate transporter, chromate ion transporter
HCLKBIDA_01203 1.8e-44 M1-594 S Thiamine-binding protein
HCLKBIDA_01204 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCLKBIDA_01205 3.4e-242
HCLKBIDA_01207 1.5e-237 gntT EG gluconate transmembrane transporter activity
HCLKBIDA_01208 1.5e-166 2.7.1.196, 2.7.1.205 K sequence-specific DNA binding
HCLKBIDA_01209 1e-124 S protein conserved in bacteria
HCLKBIDA_01210 3e-63
HCLKBIDA_01212 3.9e-93 ssuE 1.5.1.38 S FMN reductase
HCLKBIDA_01213 1.5e-180 P ABC transporter substrate-binding protein
HCLKBIDA_01214 1.1e-211 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HCLKBIDA_01215 4.4e-135 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCLKBIDA_01216 8.2e-134 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HCLKBIDA_01217 9.4e-95 K Transcriptional regulator PadR-like family
HCLKBIDA_01218 8.7e-164 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HCLKBIDA_01219 1.8e-123 K FCD
HCLKBIDA_01220 3.9e-223 S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_01221 3.9e-201 S oxidoreductase
HCLKBIDA_01222 3.1e-184 G Bacterial extracellular solute-binding protein, family 7
HCLKBIDA_01223 4.2e-78 G Tripartite ATP-independent periplasmic transporters, DctQ component
HCLKBIDA_01224 2.7e-212 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HCLKBIDA_01225 8e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HCLKBIDA_01226 5.6e-219 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HCLKBIDA_01227 4.6e-186 cysP P phosphate transporter
HCLKBIDA_01228 5.5e-112 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HCLKBIDA_01229 1.7e-276 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HCLKBIDA_01230 1.3e-142 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 C CbiX
HCLKBIDA_01231 8.3e-111 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HCLKBIDA_01232 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HCLKBIDA_01233 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HCLKBIDA_01234 7.4e-20
HCLKBIDA_01235 4.6e-160 V ABC transporter
HCLKBIDA_01236 4e-60 gntR1 K GntR family transcriptional regulator
HCLKBIDA_01237 4.4e-219 mii 5.3.3.6 S PrpF protein
HCLKBIDA_01238 6.1e-68 S Tripartite tricarboxylate transporter TctB family
HCLKBIDA_01239 1.4e-262 S Tripartite tricarboxylate transporter TctA family
HCLKBIDA_01240 1.3e-212 S Tripartite tricarboxylate transporter family receptor
HCLKBIDA_01241 1.3e-167 yraN K Transcriptional regulator
HCLKBIDA_01242 4.3e-200 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
HCLKBIDA_01243 3.9e-292 C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
HCLKBIDA_01244 3.6e-196 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HCLKBIDA_01245 1.1e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HCLKBIDA_01246 4.8e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCLKBIDA_01247 5.3e-104 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HCLKBIDA_01248 2.7e-103 tetR K Bacterial regulatory proteins, tetR family
HCLKBIDA_01249 8.9e-183 ybcL EGP Major facilitator Superfamily
HCLKBIDA_01250 6.2e-166 arsB P Arsenic resistance protein
HCLKBIDA_01251 6e-97
HCLKBIDA_01252 1.6e-131 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HCLKBIDA_01253 6.3e-45 2.7.1.196, 2.7.1.205 G phosphotransferase system
HCLKBIDA_01254 3.5e-52 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
HCLKBIDA_01255 2.1e-241 ywbA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCLKBIDA_01256 1.1e-253 celF 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HCLKBIDA_01257 1.1e-138 chbG 2.7.1.196, 2.7.1.205, 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
HCLKBIDA_01258 6.1e-137 K UTRA
HCLKBIDA_01259 0.0 chiA 3.2.1.14 GH18 G Glycoside Hydrolase Family 18
HCLKBIDA_01260 5.1e-42 S Family of unknown function (DUF5391)
HCLKBIDA_01261 9.3e-56 S Protein of unknown function (DUF1093)
HCLKBIDA_01262 1e-226 ybfB G COG0477 Permeases of the major facilitator superfamily
HCLKBIDA_01263 5.7e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HCLKBIDA_01264 2.8e-246 kynU 3.7.1.3 E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
HCLKBIDA_01265 3e-116 kynB 3.5.1.9 S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HCLKBIDA_01266 2.2e-154 kynA 1.13.11.11 E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
HCLKBIDA_01267 9.5e-206 E Spore germination protein
HCLKBIDA_01269 1.7e-221 gerKC S spore germination
HCLKBIDA_01270 5e-271 gerKA EG Spore germination protein
HCLKBIDA_01271 7.5e-135 ygbI K DeoR C terminal sensor domain
HCLKBIDA_01272 6.8e-237 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
HCLKBIDA_01273 2.5e-186 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
HCLKBIDA_01274 1.5e-218 gntP EG GntP family permease
HCLKBIDA_01275 6.7e-153 araQ5 P PFAM binding-protein-dependent transport systems inner membrane component
HCLKBIDA_01276 6.4e-160 cebF P PFAM binding-protein-dependent transport systems inner membrane component
HCLKBIDA_01277 7.1e-231 lacE3 G PFAM extracellular solute-binding protein family 1
HCLKBIDA_01279 1.8e-193 citH C Citrate transporter
HCLKBIDA_01280 2.4e-25 citH C Citrate transporter
HCLKBIDA_01281 2.4e-130 T Response regulator receiver domain
HCLKBIDA_01282 2.2e-293 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HCLKBIDA_01283 5.2e-253 argE 3.5.1.16 E Acetylornithine deacetylase
HCLKBIDA_01284 6.3e-125 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HCLKBIDA_01285 9.1e-195 pslL G Acyltransferase family
HCLKBIDA_01286 3e-162 3.13.1.3 P YhfZ C-terminal domain
HCLKBIDA_01287 4.2e-56 S PRD domain
HCLKBIDA_01288 1.2e-58 yhfU S Protein of unknown function DUF2620
HCLKBIDA_01289 1.6e-222 yhfT S Protein of unknown function
HCLKBIDA_01290 1.2e-174 php S Phosphotriesterase family
HCLKBIDA_01291 1e-204 2.9.1.1 E Cys/Met metabolism PLP-dependent enzyme
HCLKBIDA_01292 4e-220 yhfX E Alanine racemase, N-terminal domain
HCLKBIDA_01293 5.7e-230 yhfW G Metalloenzyme superfamily
HCLKBIDA_01295 0.0 O DnaJ molecular chaperone homology domain
HCLKBIDA_01296 0.0 hscC O Hsp70 protein
HCLKBIDA_01297 1.9e-141 IQ Enoyl-(Acyl carrier protein) reductase
HCLKBIDA_01298 2.1e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HCLKBIDA_01299 4.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HCLKBIDA_01300 3e-175 agpT K AraC-like ligand binding domain
HCLKBIDA_01301 7e-250 ugpB1 G Bacterial extracellular solute-binding protein
HCLKBIDA_01302 2.4e-148 M1-465 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01303 2.3e-159 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01304 1.2e-48 esxA S Belongs to the WXG100 family
HCLKBIDA_01305 7.2e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
HCLKBIDA_01306 1.4e-213 essB S WXG100 protein secretion system (Wss), protein YukC
HCLKBIDA_01307 1.1e-183 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HCLKBIDA_01308 0.0 esaA S domain protein
HCLKBIDA_01309 4.6e-71 S Family of unknown function (DUF5383)
HCLKBIDA_01310 8.3e-45
HCLKBIDA_01311 2.5e-47
HCLKBIDA_01312 9.9e-46
HCLKBIDA_01313 2.5e-241 S nuclease activity
HCLKBIDA_01314 8.9e-07
HCLKBIDA_01315 5.5e-48
HCLKBIDA_01316 1.8e-09 S nuclease activity
HCLKBIDA_01317 1.9e-07
HCLKBIDA_01318 6.3e-09 UW nuclease activity
HCLKBIDA_01319 1.4e-10
HCLKBIDA_01323 8e-48
HCLKBIDA_01325 1.4e-166 glcA G Glycoside hydrolase family 16
HCLKBIDA_01326 2.7e-16
HCLKBIDA_01330 3.1e-130 lolD-2 V COG1136 ABC-type antimicrobial peptide transport system, ATPase component
HCLKBIDA_01331 0.0 Q FtsX-like permease family
HCLKBIDA_01332 3.2e-89 K Transcriptional regulator PadR-like family
HCLKBIDA_01333 1.1e-80 2.3.1.128 K Acetyltransferase (GNAT) domain
HCLKBIDA_01334 3.7e-140 K Helix-turn-helix domain, rpiR family
HCLKBIDA_01335 4.6e-115 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HCLKBIDA_01336 4e-284 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCLKBIDA_01337 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HCLKBIDA_01338 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCLKBIDA_01339 0.0 narH 1.7.5.1 C Nitrate reductase, beta
HCLKBIDA_01340 2.9e-116 narJ C Nitrate reductase delta subunit
HCLKBIDA_01341 3.4e-126 narI 1.7.5.1 C nitrate reductase, gamma subunit
HCLKBIDA_01342 9.3e-83 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
HCLKBIDA_01343 2.5e-200 nreB 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HCLKBIDA_01344 3.3e-115 nreC T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCLKBIDA_01345 2.9e-279 narK P COG2223 Nitrate nitrite transporter
HCLKBIDA_01346 3.5e-129 ywiC S YwiC-like protein
HCLKBIDA_01347 0.0 G Bacterial extracellular solute-binding protein
HCLKBIDA_01348 8.3e-307 2.7.13.3 T Histidine kinase
HCLKBIDA_01349 9.4e-228 T cheY-homologous receiver domain
HCLKBIDA_01350 6.7e-173 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01351 3.5e-160 U Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01352 7.4e-39
HCLKBIDA_01353 7.5e-46 yvrI K RNA polymerase
HCLKBIDA_01354 8.8e-93 ssuE 1.5.1.38 S FMN reductase
HCLKBIDA_01355 8.7e-248 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCLKBIDA_01356 1.7e-57 S Dinitrogenase iron-molybdenum cofactor
HCLKBIDA_01357 6.1e-140 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HCLKBIDA_01358 3.8e-204 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HCLKBIDA_01359 3.5e-177 P ABC transporter substrate-binding protein
HCLKBIDA_01360 8.8e-139 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCLKBIDA_01361 8.3e-265 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCLKBIDA_01362 1.7e-165 gltC K Transcriptional regulator
HCLKBIDA_01363 3.3e-49 czrA K transcriptional
HCLKBIDA_01364 7.8e-150 czcD P COG1230 Co Zn Cd efflux system component
HCLKBIDA_01365 3.9e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCLKBIDA_01366 8.4e-116 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HCLKBIDA_01367 5.8e-180 K WYL domain
HCLKBIDA_01368 1.7e-173 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_01369 7.1e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCLKBIDA_01370 4.1e-127 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HCLKBIDA_01371 4.4e-194 purR11 K helix_turn _helix lactose operon repressor
HCLKBIDA_01372 0.0 DSE4 M glycoside hydrolase family 81
HCLKBIDA_01373 2.6e-117 4.4.1.3, 5.3.1.15 S Cupin
HCLKBIDA_01374 1.9e-30
HCLKBIDA_01376 1.4e-105
HCLKBIDA_01377 5.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HCLKBIDA_01378 1.8e-190 vraS 2.7.13.3 T Histidine kinase
HCLKBIDA_01379 2.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCLKBIDA_01380 1.8e-111 modB P COG4149 ABC-type molybdate transport system, permease component
HCLKBIDA_01381 7.4e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HCLKBIDA_01382 5.6e-307 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HCLKBIDA_01383 3.4e-26
HCLKBIDA_01384 1.6e-301 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HCLKBIDA_01385 0.0 3.6.3.8 P COG0474 Cation transport ATPase
HCLKBIDA_01386 1.8e-147 S GNAT acetyltransferase
HCLKBIDA_01387 5e-145 tagG GM Transport permease protein
HCLKBIDA_01388 2.7e-170 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HCLKBIDA_01389 1.4e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HCLKBIDA_01390 3.9e-44 S Membrane
HCLKBIDA_01391 2.3e-201 frvX 3.2.1.4 GH5,GH9 G M42 glutamyl aminopeptidase
HCLKBIDA_01392 9.6e-77
HCLKBIDA_01393 6.5e-75
HCLKBIDA_01394 1.5e-52 K Transcriptional regulator PadR-like family
HCLKBIDA_01395 8.1e-185 kdgR K transcriptional
HCLKBIDA_01396 1.3e-182 dctP_1 G Bacterial extracellular solute-binding protein, family 7
HCLKBIDA_01397 1.6e-85 G Tripartite ATP-independent periplasmic transporters, DctQ component
HCLKBIDA_01398 6e-201 MA20_17100 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HCLKBIDA_01399 4.1e-38 4.2.1.46, 5.1.3.2 GM NAD dependent epimerase/dehydratase family
HCLKBIDA_01400 1.9e-46 4.2.1.46, 5.1.3.2 GM NAD dependent epimerase/dehydratase family
HCLKBIDA_01402 0.0 otrA J Elongation factor G, domain IV
HCLKBIDA_01404 2.6e-230 S Putative esterase
HCLKBIDA_01405 3.5e-91 yvdQ S Protein of unknown function (DUF3231)
HCLKBIDA_01406 3.6e-45 ycbP S Protein of unknown function (DUF2512)
HCLKBIDA_01407 2e-143 yqjF S Uncharacterized conserved protein (COG2071)
HCLKBIDA_01409 8.7e-215 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
HCLKBIDA_01410 9.4e-261 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HCLKBIDA_01411 5e-252 S Membrane
HCLKBIDA_01412 1e-59 pucM 3.5.2.17 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HCLKBIDA_01413 1.1e-181 uox 1.7.3.3, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HCLKBIDA_01414 8e-88 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 S OHCU decarboxylase
HCLKBIDA_01415 2.5e-308 pucR QT COG2508 Regulator of polyketide synthase expression
HCLKBIDA_01416 2.3e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HCLKBIDA_01417 2.3e-242 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HCLKBIDA_01418 2.1e-91 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HCLKBIDA_01419 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HCLKBIDA_01420 6.3e-165 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HCLKBIDA_01421 3.2e-107 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HCLKBIDA_01422 2.8e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HCLKBIDA_01423 1.4e-186 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HCLKBIDA_01424 6.4e-146 MA20_40340 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01425 8.2e-140 P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HCLKBIDA_01426 3.3e-189 P NMT1-like family
HCLKBIDA_01427 2.7e-144 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01428 1.1e-136 P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HCLKBIDA_01429 0.0 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCLKBIDA_01430 5.5e-186 cbrA5 P Ferrichrome ABC transporter substrate-binding protein
HCLKBIDA_01431 1.5e-68 hit FG Scavenger mRNA decapping enzyme C-term binding
HCLKBIDA_01432 2.9e-81 nsrR K Transcriptional regulator
HCLKBIDA_01433 5e-81 6.3.3.2 S ASCH
HCLKBIDA_01434 0.0 uidA G Belongs to the glycosyl hydrolase 2 family
HCLKBIDA_01435 6.4e-154 fldX 1.1.1.31 I Domain of unknown function (DUF1932)
HCLKBIDA_01436 6.3e-154 K Helix-turn-helix domain, rpiR family
HCLKBIDA_01437 1.7e-116 H Methyltransferase
HCLKBIDA_01438 1.8e-31
HCLKBIDA_01439 3.3e-242 G Tripartite ATP-independent periplasmic transporter, DctM component
HCLKBIDA_01440 3.9e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCLKBIDA_01441 7.7e-182 K Transcriptional regulator
HCLKBIDA_01442 1.4e-256 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCLKBIDA_01443 9.8e-304 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
HCLKBIDA_01444 9e-184 scrR K helix_turn _helix lactose operon repressor
HCLKBIDA_01445 1.9e-115 drgA C nitroreductase
HCLKBIDA_01446 1.7e-60 K helix_turn_helix, mercury resistance
HCLKBIDA_01447 9.5e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HCLKBIDA_01448 5.3e-136 ycsF S Belongs to the UPF0271 (lamB) family
HCLKBIDA_01449 3e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HCLKBIDA_01450 2.1e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HCLKBIDA_01451 2.2e-139 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HCLKBIDA_01452 3e-264 G Bacterial extracellular solute-binding protein
HCLKBIDA_01453 5.6e-172 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01454 1.6e-160 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_01455 4.9e-139 K helix_turn_helix, mercury resistance
HCLKBIDA_01456 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HCLKBIDA_01458 5.9e-83
HCLKBIDA_01459 5.8e-255 gltD 1.3.1.1 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HCLKBIDA_01460 1.7e-232 preA 1.3.1.1 CF dihydroorotate dehydrogenase
HCLKBIDA_01461 3.6e-271 hyuA 3.5.2.2 F Amidohydrolase family
HCLKBIDA_01462 4.4e-07
HCLKBIDA_01463 5.4e-231 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HCLKBIDA_01464 7.6e-255 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCLKBIDA_01465 5.4e-66 F PFAM AIG2 family protein
HCLKBIDA_01466 2.1e-42 S Integral membrane protein
HCLKBIDA_01467 2.8e-225 K helix_turn_helix, arabinose operon control protein
HCLKBIDA_01468 9.3e-257 S Hypothetical glycosyl hydrolase 6
HCLKBIDA_01469 4.1e-225 G Bacterial extracellular solute-binding protein
HCLKBIDA_01470 9.3e-129 G ABC transporter permease
HCLKBIDA_01471 1.1e-146 G ABC-type polysaccharide transport system, permease component
HCLKBIDA_01472 1.9e-273 3.2.1.23 G beta-galactosidase
HCLKBIDA_01473 6.7e-239 S Hypothetical glycosyl hydrolase 6
HCLKBIDA_01474 9.7e-110 glxR 1.1.1.31, 1.1.1.60 I 3-hydroxyisobutyrate dehydrogenase
HCLKBIDA_01477 1.6e-165 S Tetratricopeptide repeat
HCLKBIDA_01478 4.1e-289 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 T Domain present in phytochromes and cGMP-specific phosphodiesterases.
HCLKBIDA_01479 4.1e-270 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCLKBIDA_01480 2.3e-156 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HCLKBIDA_01481 1.4e-128 S Protein of unknown function (DUF3100)
HCLKBIDA_01482 1.4e-72 S An automated process has identified a potential problem with this gene model
HCLKBIDA_01483 5e-142 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HCLKBIDA_01484 2.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HCLKBIDA_01485 1.1e-116 ywqC M biosynthesis protein
HCLKBIDA_01486 2.7e-171 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HCLKBIDA_01487 1.5e-83 S Tetratrico peptide repeat
HCLKBIDA_01488 2.4e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HCLKBIDA_01489 2.6e-79 FG Scavenger mRNA decapping enzyme C-term binding
HCLKBIDA_01490 3.9e-229 rodA D Belongs to the SEDS family
HCLKBIDA_01491 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HCLKBIDA_01492 6.3e-168 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HCLKBIDA_01493 9e-46 HA62_12640 S GCN5-related N-acetyl-transferase
HCLKBIDA_01494 9.1e-231
HCLKBIDA_01495 4e-242 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCLKBIDA_01496 8.4e-224 lytE M NlpC/P60 family
HCLKBIDA_01497 3.6e-151 Q N-acetyltransferase
HCLKBIDA_01498 5.8e-83 yisT S DinB family
HCLKBIDA_01499 1.7e-96 speG_2 2.3.1.57 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HCLKBIDA_01500 3.7e-293 pip S YhgE Pip N-terminal domain protein
HCLKBIDA_01501 2.7e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCLKBIDA_01502 5.6e-146 estA S Putative esterase
HCLKBIDA_01503 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCLKBIDA_01504 1.4e-195 S Spore germination B3/ GerAC like, C-terminal
HCLKBIDA_01505 2.7e-197 E Spore germination protein
HCLKBIDA_01506 4.4e-275 P Spore gernimation protein GerA
HCLKBIDA_01507 1.2e-61 epuA S DNA-directed RNA polymerase subunit beta
HCLKBIDA_01508 5.1e-142 flhP N flagellar basal body
HCLKBIDA_01509 7.4e-141 flhO N flagellar basal body
HCLKBIDA_01510 1.6e-180 mbl D Rod shape-determining protein
HCLKBIDA_01511 3.6e-45 spoIIID K Stage III sporulation protein D
HCLKBIDA_01512 1.2e-46 ykkD P Multidrug resistance protein
HCLKBIDA_01513 1.1e-53 sugE P Multidrug resistance protein
HCLKBIDA_01514 3.4e-131 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HCLKBIDA_01515 3.6e-188 spoIID D Stage II sporulation protein D
HCLKBIDA_01516 2.6e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCLKBIDA_01517 2.3e-22 ywmB S TATA-box binding
HCLKBIDA_01518 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HCLKBIDA_01519 6.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCLKBIDA_01520 1.7e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCLKBIDA_01521 1.8e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCLKBIDA_01522 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCLKBIDA_01523 1.3e-31 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCLKBIDA_01524 1.4e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCLKBIDA_01525 2.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
HCLKBIDA_01526 7.3e-12 S ATP synthase I chain
HCLKBIDA_01527 1.4e-23 atpI S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
HCLKBIDA_01528 0.0 vpr O Belongs to the peptidase S8 family
HCLKBIDA_01529 4.6e-90 panZ K -acetyltransferase
HCLKBIDA_01530 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCLKBIDA_01531 1.1e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCLKBIDA_01532 5e-96 ywlG S Belongs to the UPF0340 family
HCLKBIDA_01533 4.9e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HCLKBIDA_01534 7.6e-151 mcpA NT Chemotaxis
HCLKBIDA_01535 1e-72 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCLKBIDA_01536 1.5e-92 mntP P Probably functions as a manganese efflux pump
HCLKBIDA_01537 1.6e-61 S Regulator of ribonuclease activity B
HCLKBIDA_01538 9.5e-184 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCLKBIDA_01539 1.7e-73 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HCLKBIDA_01540 7.5e-112 spoIIR S stage II sporulation protein R
HCLKBIDA_01541 3.2e-161 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCLKBIDA_01542 8.6e-177 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCLKBIDA_01543 1.7e-259 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCLKBIDA_01544 4.2e-74
HCLKBIDA_01545 2.9e-110 tdk 2.7.1.21 F thymidine kinase
HCLKBIDA_01546 3.8e-40 rpmE2 J Ribosomal protein L31
HCLKBIDA_01547 1.3e-235 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCLKBIDA_01548 7e-178 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HCLKBIDA_01549 3.5e-209 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCLKBIDA_01550 1.7e-114 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCLKBIDA_01551 2.7e-160 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HCLKBIDA_01552 2.5e-59 spo0F T response regulator
HCLKBIDA_01553 1.2e-91 ywjG S Domain of unknown function (DUF2529)
HCLKBIDA_01554 4.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCLKBIDA_01555 6.1e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCLKBIDA_01556 8.5e-108 kstR2_2 K Transcriptional regulator
HCLKBIDA_01557 2.5e-206 mmgC I acyl-CoA dehydrogenase
HCLKBIDA_01558 3.3e-155 hbdA 1.1.1.157 I Dehydrogenase
HCLKBIDA_01559 8.8e-215 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
HCLKBIDA_01560 0.0 fadF C COG0247 Fe-S oxidoreductase
HCLKBIDA_01561 2.3e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HCLKBIDA_01562 2.3e-73 yqgC S protein conserved in bacteria
HCLKBIDA_01563 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HCLKBIDA_01564 1e-75 ywiB S protein conserved in bacteria
HCLKBIDA_01565 6e-168 speB 3.5.3.11 E Belongs to the arginase family
HCLKBIDA_01566 4.8e-159 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HCLKBIDA_01567 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCLKBIDA_01568 1.7e-156 vipF 2.3.1.128 K Acetyltransferase (GNAT) domain
HCLKBIDA_01569 0.0 pepF E oligoendopeptidase F
HCLKBIDA_01570 1.9e-98 ywhD S YwhD family
HCLKBIDA_01571 8.5e-199 F S-adenosylhomocysteine deaminase activity
HCLKBIDA_01572 6.4e-125 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HCLKBIDA_01573 1.9e-26 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HCLKBIDA_01575 2.6e-91 ywgA 2.1.1.72, 3.1.21.3
HCLKBIDA_01576 2.6e-252 ywfO S COG1078 HD superfamily phosphohydrolases
HCLKBIDA_01577 2.1e-198 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCLKBIDA_01578 4.8e-151 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HCLKBIDA_01579 2.9e-182 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HCLKBIDA_01580 3e-142 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HCLKBIDA_01581 1.2e-145 ywfI C May function as heme-dependent peroxidase
HCLKBIDA_01582 2e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCLKBIDA_01583 5.8e-48
HCLKBIDA_01584 1.3e-184 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HCLKBIDA_01585 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HCLKBIDA_01586 1.4e-161 natA1 V ABC transporter
HCLKBIDA_01587 1.2e-62 K helix_turn_helix gluconate operon transcriptional repressor
HCLKBIDA_01588 8.4e-131
HCLKBIDA_01589 1.3e-78 cwlJ 3.5.1.28 M Cell wall
HCLKBIDA_01590 3e-68 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HCLKBIDA_01591 1.3e-58 ywdK S small membrane protein
HCLKBIDA_01592 2.5e-112 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCLKBIDA_01593 1.3e-271 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCLKBIDA_01594 5.2e-47 S Family of unknown function (DUF5327)
HCLKBIDA_01595 1.4e-135 dnaQ2 2.7.7.7 L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
HCLKBIDA_01596 3.9e-170 2.7.7.7 T Putative nucleotidyltransferase substrate binding domain
HCLKBIDA_01597 1.3e-229 amtB P Ammonium transporter
HCLKBIDA_01598 1.4e-179 abrB S Pfam:AmoA
HCLKBIDA_01599 3e-138 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCLKBIDA_01600 2.2e-233 BH2250 S protein conserved in bacteria
HCLKBIDA_01601 4e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCLKBIDA_01602 1.2e-277 hutH 4.3.1.3 E Histidine ammonia-lyase
HCLKBIDA_01603 3.4e-47 S Branched-chain amino acid transport protein (AzlD)
HCLKBIDA_01604 1.3e-123 azlC E AzlC protein
HCLKBIDA_01605 5.9e-277 gntR9 K Alanine-glyoxylate amino-transferase
HCLKBIDA_01606 2.6e-129 S B3/4 domain
HCLKBIDA_01607 2.1e-235 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E methionine gamma-lyase
HCLKBIDA_01608 8.8e-192 I Fatty acid desaturase
HCLKBIDA_01609 9e-264 6.3.1.2 E Glutamine synthetase, catalytic domain
HCLKBIDA_01610 8.5e-76 S Protein of unknown function (DUF4064)
HCLKBIDA_01611 6.3e-87 K Acetyltransferase (GNAT) domain
HCLKBIDA_01612 3.5e-261 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCLKBIDA_01613 3.2e-75 bdbA CO Thioredoxin
HCLKBIDA_01614 1.9e-71 bdbC O Required for disulfide bond formation in some proteins
HCLKBIDA_01615 3.4e-288 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HCLKBIDA_01617 1.7e-82 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HCLKBIDA_01618 1.5e-155 yuaG 3.4.21.72 S protein conserved in bacteria
HCLKBIDA_01619 2.3e-136 map 3.4.11.18 E Methionine aminopeptidase
HCLKBIDA_01620 5.7e-120 ydbC G Domain of unknown function (DUF4937
HCLKBIDA_01621 4.3e-250 3.1.3.1 P Belongs to the alkaline phosphatase family
HCLKBIDA_01622 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCLKBIDA_01623 4.4e-230 ywbD 2.1.1.191 J Methyltransferase
HCLKBIDA_01624 2.6e-43 ydzA EGP Major facilitator Superfamily
HCLKBIDA_01625 6e-55 yflT S Heat induced stress protein YflT
HCLKBIDA_01626 7.5e-100 S UPF0302 domain
HCLKBIDA_01627 2.3e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HCLKBIDA_01628 2.2e-160 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HCLKBIDA_01629 1.2e-140 troB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HCLKBIDA_01630 3.2e-175 troA P Belongs to the bacterial solute-binding protein 9 family
HCLKBIDA_01631 5.3e-147 ycsE 3.1.3.104 S hydrolases of the HAD superfamily
HCLKBIDA_01632 1.7e-254 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
HCLKBIDA_01633 1.3e-226 S Acetyltransferase
HCLKBIDA_01634 1.8e-244 NT chemotaxis protein
HCLKBIDA_01635 0.0 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCLKBIDA_01636 7.1e-212 yxlH EGP Major facilitator Superfamily
HCLKBIDA_01637 3.8e-96 S DinB superfamily
HCLKBIDA_01638 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HCLKBIDA_01639 0.0 ywjA V ABC transporter
HCLKBIDA_01640 3.5e-174 murB 1.3.1.98 M cell wall formation
HCLKBIDA_01641 2.2e-108 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HCLKBIDA_01642 2.2e-111 yrbG3 S membrane
HCLKBIDA_01643 1.4e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HCLKBIDA_01644 0.0 L AAA domain
HCLKBIDA_01645 6.4e-72 K GrpB protein
HCLKBIDA_01646 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCLKBIDA_01647 2e-74 yosT L Bacterial transcription activator, effector binding domain
HCLKBIDA_01648 1.7e-125
HCLKBIDA_01649 4.1e-124
HCLKBIDA_01650 1.2e-291
HCLKBIDA_01651 9.1e-68
HCLKBIDA_01652 6.7e-09
HCLKBIDA_01654 5.6e-189 comGB NU COG1459 Type II secretory pathway, component PulF
HCLKBIDA_01655 3e-187 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HCLKBIDA_01656 0.0 yjcD 3.6.4.12 L DNA helicase
HCLKBIDA_01657 7e-72
HCLKBIDA_01658 2.7e-71 cotX S Spore Coat Protein X and V domain
HCLKBIDA_01661 3.4e-137
HCLKBIDA_01662 8.4e-128
HCLKBIDA_01663 2.3e-144 Q ubiE/COQ5 methyltransferase family
HCLKBIDA_01664 1.6e-60 yngL S Protein of unknown function (DUF1360)
HCLKBIDA_01665 4.4e-138 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HCLKBIDA_01666 5.4e-172 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCLKBIDA_01667 6.8e-150 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCLKBIDA_01668 2e-109 yjbM 2.7.6.5 S GTP pyrophosphokinase
HCLKBIDA_01669 5.5e-62 yjbL S Belongs to the UPF0738 family
HCLKBIDA_01670 4.2e-98 yjbK S protein conserved in bacteria
HCLKBIDA_01671 3e-98 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HCLKBIDA_01672 5.6e-73 yjbI S COG2346 Truncated hemoglobins
HCLKBIDA_01673 1.9e-172 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HCLKBIDA_01675 2.2e-237 yjbF S Competence protein
HCLKBIDA_01676 2.1e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HCLKBIDA_01677 1.3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCLKBIDA_01679 9.1e-98 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCLKBIDA_01680 1e-237 S Putative glycosyl hydrolase domain
HCLKBIDA_01681 2.9e-13 yoeD G Helix-turn-helix domain
HCLKBIDA_01682 2e-112 yplQ S protein, Hemolysin III
HCLKBIDA_01683 2.1e-99 yueE S phosphohydrolase
HCLKBIDA_01684 3.3e-106 stoA CO Redoxin
HCLKBIDA_01686 3.3e-183 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HCLKBIDA_01687 3.6e-10
HCLKBIDA_01688 1.1e-141 yjbA S Belongs to the UPF0736 family
HCLKBIDA_01689 2.4e-155 yjaZ O Zn-dependent protease
HCLKBIDA_01690 8.1e-137 ywaC 2.7.6.5 S protein conserved in bacteria
HCLKBIDA_01691 3.7e-179 coaA 2.7.1.33 F Pantothenic acid kinase
HCLKBIDA_01692 2.3e-107 J protein with SCP PR1 domains
HCLKBIDA_01693 9.2e-104 3.5.1.28 M Cell Wall Hydrolase
HCLKBIDA_01695 0.0 cca 2.7.7.19, 2.7.7.72, 3.1.13.3, 3.1.3.7 J Poly A polymerase head domain
HCLKBIDA_01696 2.7e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCLKBIDA_01697 4.4e-169 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCLKBIDA_01699 1.1e-12 comZ S ComZ
HCLKBIDA_01700 1.1e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCLKBIDA_01701 1.9e-158 5.1.3.2 GM RmlD substrate binding domain
HCLKBIDA_01702 3.3e-121 yjaU I carboxylic ester hydrolase activity
HCLKBIDA_01703 1.5e-172 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCLKBIDA_01704 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HCLKBIDA_01705 1.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCLKBIDA_01706 8.4e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HCLKBIDA_01707 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HCLKBIDA_01708 2.1e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HCLKBIDA_01709 9.2e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HCLKBIDA_01710 6.7e-167 ctaG S cytochrome c oxidase
HCLKBIDA_01711 9.5e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HCLKBIDA_01712 1.8e-78 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) domain
HCLKBIDA_01713 2.2e-108
HCLKBIDA_01714 3.2e-231 ywqB S zinc ion binding
HCLKBIDA_01715 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HCLKBIDA_01717 1.9e-30 ipi S Intracellular proteinase inhibitor
HCLKBIDA_01718 2.8e-146 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HCLKBIDA_01719 5.6e-149 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HCLKBIDA_01720 2.3e-41
HCLKBIDA_01721 9.9e-64 ytwF P Sulfurtransferase
HCLKBIDA_01722 7.5e-92
HCLKBIDA_01723 7.9e-285 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HCLKBIDA_01724 4.3e-155 ykgA E Amidinotransferase
HCLKBIDA_01725 2.3e-47 S IDEAL
HCLKBIDA_01726 0.0 asnB 6.3.5.4 E Asparagine synthase
HCLKBIDA_01727 2.7e-73 cheW NT chemotaxis
HCLKBIDA_01728 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HCLKBIDA_01729 0.0 recB 3.1.11.5, 3.1.12.1, 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HCLKBIDA_01730 0.0 addB 3.6.4.12 L exonuclease activity
HCLKBIDA_01731 7.1e-62
HCLKBIDA_01732 6.5e-111 phoU P Plays a role in the regulation of phosphate uptake
HCLKBIDA_01733 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCLKBIDA_01734 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCLKBIDA_01735 6.1e-160 pstA P Phosphate transport system permease
HCLKBIDA_01736 6.4e-160 pstC P probably responsible for the translocation of the substrate across the membrane
HCLKBIDA_01737 7.4e-169 pstS P Phosphate
HCLKBIDA_01738 4.2e-83 S DinB family
HCLKBIDA_01739 3.9e-268 nylA 3.5.1.4 J Belongs to the amidase family
HCLKBIDA_01740 1.6e-131 S Peptidase C26
HCLKBIDA_01741 1.3e-212 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HCLKBIDA_01742 1.9e-118 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
HCLKBIDA_01744 6.5e-215 Q COG1228 Imidazolonepropionase and related amidohydrolases
HCLKBIDA_01745 4e-44 abrB K SpoVT / AbrB like domain
HCLKBIDA_01746 1.7e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HCLKBIDA_01747 1.8e-56 ysxB J ribosomal protein
HCLKBIDA_01748 2.2e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
HCLKBIDA_01749 1.2e-272 rng J ribonuclease, Rne Rng family
HCLKBIDA_01750 1.5e-152 spoIVFB S Stage IV sporulation protein
HCLKBIDA_01751 2.9e-131 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HCLKBIDA_01752 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HCLKBIDA_01753 6.3e-94 bioY S BioY family
HCLKBIDA_01754 3.4e-74 moaC 4.6.1.17 H MoaC family
HCLKBIDA_01755 1.9e-92 yfkM 3.5.1.124 S protease
HCLKBIDA_01756 1.6e-140 minD D Belongs to the ParA family
HCLKBIDA_01757 2.3e-122 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HCLKBIDA_01758 8.8e-74 mreD M shape-determining protein
HCLKBIDA_01759 2.1e-160 mreC M Involved in formation and maintenance of cell shape
HCLKBIDA_01760 8.9e-187 mreB D Rod shape-determining protein MreB
HCLKBIDA_01761 4.4e-121 radC E Belongs to the UPF0758 family
HCLKBIDA_01762 2.4e-104 maf D septum formation protein Maf
HCLKBIDA_01763 0.0 yuxL 3.4.19.1 EU peptidase
HCLKBIDA_01764 9.1e-198
HCLKBIDA_01765 2.2e-120 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HCLKBIDA_01766 1e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HCLKBIDA_01767 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCLKBIDA_01768 4.9e-31
HCLKBIDA_01769 1.3e-105
HCLKBIDA_01770 1.5e-191 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HCLKBIDA_01771 2.5e-166
HCLKBIDA_01772 1.2e-179 spoVID M stage VI sporulation protein D
HCLKBIDA_01773 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HCLKBIDA_01774 3.7e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HCLKBIDA_01775 1.7e-139 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HCLKBIDA_01776 1.4e-170 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HCLKBIDA_01777 1.4e-147 hemX O cytochrome C
HCLKBIDA_01778 2.8e-249 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HCLKBIDA_01779 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HCLKBIDA_01780 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HCLKBIDA_01781 4.6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HCLKBIDA_01782 1e-237 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCLKBIDA_01783 7.9e-233 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCLKBIDA_01784 4.5e-180 trxA2 O COG0457 FOG TPR repeat
HCLKBIDA_01785 2.4e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCLKBIDA_01786 6.1e-271 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCLKBIDA_01787 1.5e-197 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HCLKBIDA_01788 7.3e-286 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HCLKBIDA_01789 1.2e-178 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HCLKBIDA_01790 3.8e-85 ilvN 2.2.1.6 E Acetolactate synthase
HCLKBIDA_01791 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HCLKBIDA_01792 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HCLKBIDA_01793 3.1e-74
HCLKBIDA_01794 9e-273 M Glycosyl transferase family group 2
HCLKBIDA_01795 5.2e-308 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HCLKBIDA_01799 5.5e-97 ysnB S Phosphoesterase
HCLKBIDA_01800 1.8e-107 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCLKBIDA_01801 8e-137 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HCLKBIDA_01802 2.2e-183 gerM S COG5401 Spore germination protein
HCLKBIDA_01803 1.7e-195 yceA S Belongs to the UPF0176 family
HCLKBIDA_01804 2.5e-23 C 4Fe-4S binding domain
HCLKBIDA_01805 4.8e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HCLKBIDA_01806 1.9e-80 ysmB 2.4.2.28 K transcriptional
HCLKBIDA_01807 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCLKBIDA_01808 1.3e-38 ptsH G phosphocarrier protein HPr
HCLKBIDA_01809 1.6e-32 gerE K Transcriptional regulator
HCLKBIDA_01810 1.1e-80 fcbC S thioesterase
HCLKBIDA_01811 9.5e-146 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HCLKBIDA_01812 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HCLKBIDA_01813 2.7e-111 sdhC C succinate dehydrogenase
HCLKBIDA_01814 7.2e-229 ktrB P COG0168 Trk-type K transport systems, membrane components
HCLKBIDA_01815 1.3e-75 yslB S Protein of unknown function (DUF2507)
HCLKBIDA_01816 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCLKBIDA_01817 1.8e-53 trxA O Belongs to the thioredoxin family
HCLKBIDA_01818 4.1e-173 etfA C Electron transfer flavoprotein
HCLKBIDA_01819 1.1e-133 etfB C Electron transfer flavoprotein
HCLKBIDA_01820 1.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HCLKBIDA_01821 1e-102 fadR K Transcriptional regulator
HCLKBIDA_01822 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCLKBIDA_01823 2.4e-66 yshE S membrane
HCLKBIDA_01824 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCLKBIDA_01825 0.0 polX L COG1796 DNA polymerase IV (family X)
HCLKBIDA_01826 6e-86 cvpA S membrane protein, required for colicin V production
HCLKBIDA_01827 3.1e-34 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HCLKBIDA_01828 2.6e-225 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCLKBIDA_01829 2e-194 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCLKBIDA_01830 1.1e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCLKBIDA_01831 1.4e-30 sspI S Belongs to the SspI family
HCLKBIDA_01833 7.1e-17
HCLKBIDA_01834 2.8e-204 ysdC G COG1363 Cellulase M and related proteins
HCLKBIDA_01835 1.3e-64 ysdB S Sigma-w pathway protein YsdB
HCLKBIDA_01836 1.7e-263 actP S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCLKBIDA_01837 5.5e-53 S Protein of unknown function, DUF485
HCLKBIDA_01838 2.3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCLKBIDA_01839 4.4e-29 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HCLKBIDA_01840 4.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCLKBIDA_01841 2.3e-210 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HCLKBIDA_01842 1.2e-118 macB V ABC transporter, ATP-binding protein
HCLKBIDA_01843 4.9e-238 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCLKBIDA_01844 2.5e-122
HCLKBIDA_01845 2.3e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HCLKBIDA_01846 2.1e-179 strT C Aldo/keto reductase family
HCLKBIDA_01847 1e-187 S Oxidoreductase family, NAD-binding Rossmann fold
HCLKBIDA_01848 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCLKBIDA_01849 6.2e-162 ytxC S YtxC-like family
HCLKBIDA_01850 1.9e-225 mqnC 1.21.98.1, 2.5.1.120, 2.5.1.77 H Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)
HCLKBIDA_01851 1.7e-173 dnaI L Primosomal protein DnaI
HCLKBIDA_01852 2.3e-249 dnaB L Membrane attachment protein
HCLKBIDA_01853 1.8e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCLKBIDA_01854 8.8e-66
HCLKBIDA_01855 1.4e-68 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HCLKBIDA_01856 6.8e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCLKBIDA_01857 5.4e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCLKBIDA_01858 1.4e-105 ytaF P Probably functions as a manganese efflux pump
HCLKBIDA_01859 1e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCLKBIDA_01860 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCLKBIDA_01861 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HCLKBIDA_01862 4.4e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_01863 8.9e-75 lrpC K helix_turn_helix ASNC type
HCLKBIDA_01864 8.2e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HCLKBIDA_01865 2.6e-241 icd 1.1.1.42 C isocitrate
HCLKBIDA_01866 2.6e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
HCLKBIDA_01867 6.7e-73 yeaL S UPF0756 membrane protein
HCLKBIDA_01868 1.4e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HCLKBIDA_01869 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HCLKBIDA_01870 9.8e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCLKBIDA_01871 1.2e-180 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HCLKBIDA_01872 3.1e-153 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCLKBIDA_01873 9e-116 lutR_1 K helix_turn_helix gluconate operon transcriptional repressor
HCLKBIDA_01874 1.2e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HCLKBIDA_01875 0.0 dnaE 2.7.7.7 L DNA polymerase
HCLKBIDA_01876 7.2e-53 ytrH S Sporulation protein YtrH
HCLKBIDA_01877 4.2e-89 ytrI
HCLKBIDA_01878 7.3e-172 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HCLKBIDA_01879 4.6e-08 ytpI S YtpI-like protein
HCLKBIDA_01880 6.7e-240 ytoI K transcriptional regulator containing CBS domains
HCLKBIDA_01882 2.1e-128 ytkL S Belongs to the UPF0173 family
HCLKBIDA_01883 1.6e-210 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HCLKBIDA_01884 5.4e-65
HCLKBIDA_01885 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_01887 4.6e-36 L Superfamily I DNA and RNA helicases
HCLKBIDA_01888 4.6e-165 K AraC-like ligand binding domain
HCLKBIDA_01889 0.0 pbg 3.2.1.23 G beta-galactosidase
HCLKBIDA_01890 0.0 K Mga helix-turn-helix domain
HCLKBIDA_01891 2.9e-218 dho 3.5.2.3 S amidohydrolase
HCLKBIDA_01892 4.9e-51 S PRD domain
HCLKBIDA_01893 2.6e-61 S Glycine-rich SFCGS
HCLKBIDA_01894 3.5e-58 S Domain of unknown function (DUF4312)
HCLKBIDA_01895 6.2e-140 S Domain of unknown function (DUF4311)
HCLKBIDA_01896 8.6e-114 S Domain of unknown function (DUF4310)
HCLKBIDA_01897 1.1e-203 selA 2.9.1.1, 4.3.1.29 E L-seryl-tRNA selenium transferase
HCLKBIDA_01898 6.3e-123 4.1.2.14 S KDGP aldolase
HCLKBIDA_01900 2.2e-182 pld1 1.1.1.122 C Aldo/keto reductase family
HCLKBIDA_01901 9.4e-71 H RibD C-terminal domain
HCLKBIDA_01902 3.5e-58 S YjbR
HCLKBIDA_01903 2.6e-55 S Glyoxalase-like domain
HCLKBIDA_01904 2.4e-108 K helix_turn_helix, arabinose operon control protein
HCLKBIDA_01905 4.9e-96 K Winged helix DNA-binding domain
HCLKBIDA_01906 1.2e-151 pldB 3.1.1.5 I Alpha beta hydrolase
HCLKBIDA_01907 4.3e-177 rocF 3.5.3.1, 3.5.3.11 E Arginase family
HCLKBIDA_01908 3.4e-58 ydzF K HxlR-like helix-turn-helix
HCLKBIDA_01909 2e-241 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCLKBIDA_01910 5.3e-130 L DNA alkylation repair enzyme
HCLKBIDA_01911 5.7e-58 S AAA domain
HCLKBIDA_01912 2.2e-99 5.4.2.11 G Phosphoglycerate mutase family
HCLKBIDA_01913 4.2e-198 yxjM T Signal transduction histidine kinase
HCLKBIDA_01914 6.4e-111 KT LuxR family transcriptional regulator
HCLKBIDA_01915 8.9e-170 V COG1131 ABC-type multidrug transport system, ATPase component
HCLKBIDA_01916 1e-146 V ABC-2 family transporter protein
HCLKBIDA_01917 6.1e-194 V ABC-2 type transporter
HCLKBIDA_01918 1.1e-155 gspA M Glycosyl transferase family 8
HCLKBIDA_01919 8.5e-63 yxjI S LURP-one-related
HCLKBIDA_01920 3.9e-169 adcA P Belongs to the bacterial solute-binding protein 9 family
HCLKBIDA_01921 4.3e-132 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCLKBIDA_01922 4.2e-100 2.3.1.128 J Acetyltransferase (GNAT) domain
HCLKBIDA_01923 4.9e-48
HCLKBIDA_01924 1.3e-105 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCLKBIDA_01925 6.9e-273 MA20_17540 P secondary active sulfate transmembrane transporter activity
HCLKBIDA_01926 0.0 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HCLKBIDA_01927 4.9e-54 S Regulatory protein YrvL
HCLKBIDA_01928 8.4e-190 yccF K SEC-C motif
HCLKBIDA_01929 3.3e-259 sdcS P Sodium:sulfate symporter transmembrane region
HCLKBIDA_01930 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HCLKBIDA_01931 2.5e-292 cstA T Carbon starvation protein
HCLKBIDA_01932 5.1e-95
HCLKBIDA_01933 1.2e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCLKBIDA_01934 1.7e-257 scrA5 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCLKBIDA_01935 0.0 bglX 3.2.1.21 GH3 G Belongs to the glycosyl hydrolase 3 family
HCLKBIDA_01936 1.7e-278 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
HCLKBIDA_01937 5.1e-153 rhaR2 K helix_turn_helix, arabinose operon control protein
HCLKBIDA_01938 5.3e-92 mepB S MepB protein
HCLKBIDA_01939 2.8e-168 yhcH V ABC transporter, ATP-binding protein
HCLKBIDA_01940 8.7e-131 S ABC-2 family transporter protein
HCLKBIDA_01941 6.2e-61 yhcF K Transcriptional regulator
HCLKBIDA_01942 1.2e-121 V ATPases associated with a variety of cellular activities
HCLKBIDA_01943 5e-123
HCLKBIDA_01944 4.2e-200 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HCLKBIDA_01945 1.3e-81 dps P Belongs to the Dps family
HCLKBIDA_01946 5.2e-101 S B3/4 domain
HCLKBIDA_01947 8.6e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HCLKBIDA_01948 4.8e-96 ogt 1.17.99.6, 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCLKBIDA_01949 5e-81 K Acetyltransferase (GNAT) domain
HCLKBIDA_01950 5.5e-169 yhbB S Putative amidase domain
HCLKBIDA_01951 1.1e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCLKBIDA_01952 6e-89 yufK S Family of unknown function (DUF5366)
HCLKBIDA_01953 1.4e-53 hmoB 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HCLKBIDA_01954 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HCLKBIDA_01955 0.0 prkA T Ser protein kinase
HCLKBIDA_01956 1.4e-104 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HCLKBIDA_01957 3.4e-140 cysA1 S AAA domain
HCLKBIDA_01958 2.7e-216 yhbH S Belongs to the UPF0229 family
HCLKBIDA_01960 1.8e-165 K Bacterial regulatory proteins, tetR family
HCLKBIDA_01961 8.6e-268 EGP Major facilitator Superfamily
HCLKBIDA_01962 2.5e-170 drrA V COG1131 ABC-type multidrug transport system, ATPase component
HCLKBIDA_01963 2.5e-147 drrB V Transport permease protein
HCLKBIDA_01964 9e-86 S Protein of unknown function (DUF664)
HCLKBIDA_01965 1.1e-248 3.2.1.51, 4.2.2.23 GH95,PL11 G Right handed beta helix region
HCLKBIDA_01966 3.5e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_01967 2.1e-180 E Sodium:solute symporter family
HCLKBIDA_01968 1.4e-24 E Sodium:solute symporter family
HCLKBIDA_01969 2.1e-126 K UTRA
HCLKBIDA_01970 1.8e-273 4.3.2.1 E argininosuccinate lyase
HCLKBIDA_01972 3.3e-132 yvoA K transcriptional
HCLKBIDA_01973 1.9e-225 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCLKBIDA_01974 1.8e-136 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCLKBIDA_01975 2.7e-129 frp 1.5.1.39 C Oxidoreductase
HCLKBIDA_01976 1.3e-226 mtnE 2.6.1.83 E Aminotransferase
HCLKBIDA_01977 2.4e-118 ycgM Q Fumarylacetoacetate (FAA) hydrolase family
HCLKBIDA_01978 1.1e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCLKBIDA_01979 1.4e-71
HCLKBIDA_01981 4.1e-305 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HCLKBIDA_01982 8.3e-120 sfsA S Sugar fermentation stimulation protein
HCLKBIDA_01983 5.4e-300 glpD 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HCLKBIDA_01984 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HCLKBIDA_01985 4.4e-274 ycgB S Stage V sporulation protein R
HCLKBIDA_01986 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCLKBIDA_01987 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCLKBIDA_01988 9.6e-233 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCLKBIDA_01989 9.6e-150 htpX O Peptidase family M48
HCLKBIDA_01990 7.2e-95 lemA S LemA family
HCLKBIDA_01991 8.5e-218 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HCLKBIDA_01992 2.8e-257 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HCLKBIDA_01993 1.9e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HCLKBIDA_01994 5.9e-135 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HCLKBIDA_01995 4e-284 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HCLKBIDA_01997 8.1e-216
HCLKBIDA_01998 1.8e-78 K Sigma-70, region 4
HCLKBIDA_01999 2.6e-205 msmK P Belongs to the ABC transporter superfamily
HCLKBIDA_02000 1.7e-162 lrp QT PucR C-terminal helix-turn-helix domain
HCLKBIDA_02001 4.1e-22
HCLKBIDA_02002 4.2e-17 yheE S Family of unknown function (DUF5342)
HCLKBIDA_02003 7e-209 yheB S Belongs to the UPF0754 family
HCLKBIDA_02004 1.4e-54 yheA S Belongs to the UPF0342 family
HCLKBIDA_02005 1.4e-158 yhaX S hydrolases of the HAD superfamily
HCLKBIDA_02007 4.2e-42
HCLKBIDA_02008 1.3e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_02009 3.3e-261 T PhoQ Sensor
HCLKBIDA_02010 8e-182 yhaM L Shows a 3'-5' exoribonuclease activity
HCLKBIDA_02011 6.2e-45 yhaL S Sporulation protein YhaL
HCLKBIDA_02012 1.4e-160 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCLKBIDA_02014 1.7e-108 S Protein conserved in bacteria
HCLKBIDA_02015 1.2e-108 hpr K Negative regulator of protease production and sporulation
HCLKBIDA_02016 2.4e-54 yhaH D gas vesicle protein
HCLKBIDA_02017 4.6e-210 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HCLKBIDA_02018 3.8e-75 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HCLKBIDA_02019 7.1e-138 ecsA V transporter (ATP-binding protein)
HCLKBIDA_02020 1.8e-215 ecsB U ABC transporter
HCLKBIDA_02021 9.3e-127 ecsC S EcsC protein family
HCLKBIDA_02022 9.2e-122 ccdA O cytochrome c biogenesis protein
HCLKBIDA_02023 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCLKBIDA_02024 2.1e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HCLKBIDA_02025 1.3e-181 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HCLKBIDA_02026 2.8e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HCLKBIDA_02028 1.8e-101 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HCLKBIDA_02029 1.9e-223 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCLKBIDA_02030 1.8e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
HCLKBIDA_02031 6.4e-162 pheA 4.2.1.51 E Prephenate dehydratase
HCLKBIDA_02032 1.5e-90 niaR S small molecule binding protein (contains 3H domain)
HCLKBIDA_02033 1.7e-207 nifS 2.8.1.7 E Cysteine desulfurase
HCLKBIDA_02034 4.1e-289 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HCLKBIDA_02035 7.1e-150 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HCLKBIDA_02036 3.6e-210 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HCLKBIDA_02037 1.5e-182 safA M spore coat assembly protein SafA
HCLKBIDA_02038 1.9e-22 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCLKBIDA_02039 7.7e-64 1.9.3.1 C cytochrome c oxidase subunit II
HCLKBIDA_02040 8.4e-93 bofC S BofC C-terminal domain
HCLKBIDA_02041 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCLKBIDA_02042 6.8e-184 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCLKBIDA_02043 6.3e-28 yrzS S Protein of unknown function (DUF2905)
HCLKBIDA_02044 2e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCLKBIDA_02045 8.9e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCLKBIDA_02046 3.9e-38 yajC U Preprotein translocase subunit YajC
HCLKBIDA_02047 5.6e-62 yrzE S Protein of unknown function (DUF3792)
HCLKBIDA_02048 3.6e-79 ycaP S membrane
HCLKBIDA_02049 7.9e-30 yodI
HCLKBIDA_02050 1.9e-262 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCLKBIDA_02051 5.7e-22 yrzD S Post-transcriptional regulator
HCLKBIDA_02052 3e-232 secD U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HCLKBIDA_02053 1.2e-145 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HCLKBIDA_02054 1.8e-39 yrvD S Lipopolysaccharide assembly protein A domain
HCLKBIDA_02055 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HCLKBIDA_02056 4.1e-92 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCLKBIDA_02057 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCLKBIDA_02058 2.5e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCLKBIDA_02059 2.1e-188 cytR 5.1.1.1 K LacI family transcriptional regulator
HCLKBIDA_02060 1.4e-143 thuA G Trehalose utilisation
HCLKBIDA_02061 1.1e-192 S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_02062 2.7e-221 V Belongs to the UPF0214 family
HCLKBIDA_02064 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HCLKBIDA_02065 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HCLKBIDA_02066 7.6e-222 1.1.1.3 E homoserine dehydrogenase
HCLKBIDA_02067 4e-50
HCLKBIDA_02068 4.2e-219 yxjG 2.1.1.14 E Methionine synthase
HCLKBIDA_02069 6.3e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HCLKBIDA_02070 4.7e-106 rsfA S Transcriptional regulator
HCLKBIDA_02071 9.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HCLKBIDA_02072 1.6e-70 cymR K Transcriptional regulator
HCLKBIDA_02073 7.3e-214 iscS 2.8.1.7 E Cysteine desulfurase
HCLKBIDA_02074 3.9e-217 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCLKBIDA_02075 2.3e-39 S COG0457 FOG TPR repeat
HCLKBIDA_02076 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCLKBIDA_02077 9.3e-83 yrrD S protein conserved in bacteria
HCLKBIDA_02078 2.1e-30 yrzR
HCLKBIDA_02079 2.2e-188 yrrI S AI-2E family transporter
HCLKBIDA_02080 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCLKBIDA_02081 1.9e-43 yrzL S Belongs to the UPF0297 family
HCLKBIDA_02082 6.1e-73 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCLKBIDA_02083 4.1e-25 yrzB S Belongs to the UPF0473 family
HCLKBIDA_02084 2.6e-211 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCLKBIDA_02085 1.8e-116 yrrM 2.1.1.104 S O-methyltransferase
HCLKBIDA_02086 1.4e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HCLKBIDA_02087 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCLKBIDA_02088 6.7e-12 S Protein of unknown function (DUF1510)
HCLKBIDA_02089 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HCLKBIDA_02090 1.6e-149 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HCLKBIDA_02091 7.3e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCLKBIDA_02092 1.8e-10 S YrhC-like protein
HCLKBIDA_02093 1.3e-78 M1-460
HCLKBIDA_02094 1.4e-292 E Bacterial extracellular solute-binding proteins, family 5 Middle
HCLKBIDA_02095 5.9e-149 appF P ATPases associated with a variety of cellular activities
HCLKBIDA_02096 4.7e-143 oppD P Oligopeptide/dipeptide transporter, C-terminal region
HCLKBIDA_02097 4.1e-156 EP N-terminal TM domain of oligopeptide transport permease C
HCLKBIDA_02098 3.7e-152 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02099 2.6e-109 arpR K Bacterial regulatory proteins, tetR family
HCLKBIDA_02100 0.0 malS 3.2.1.1 GH13 G Carbohydrate binding domain
HCLKBIDA_02101 3.9e-113 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HCLKBIDA_02102 1.2e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
HCLKBIDA_02103 8.2e-252 S Membrane
HCLKBIDA_02104 7.1e-225 hipO3 3.5.1.47 S amidohydrolase
HCLKBIDA_02105 7.8e-169 ybaS 1.1.1.58 S Na -dependent transporter
HCLKBIDA_02106 2.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCLKBIDA_02107 5.5e-25
HCLKBIDA_02109 5.2e-54
HCLKBIDA_02110 1.4e-12 exeA
HCLKBIDA_02111 1.3e-22 EGP Major facilitator Superfamily
HCLKBIDA_02112 7.3e-77
HCLKBIDA_02113 1.3e-55 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCLKBIDA_02114 6.8e-251 S protein conserved in bacteria
HCLKBIDA_02115 8.3e-251 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCLKBIDA_02116 1.5e-109 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HCLKBIDA_02118 2.2e-148 3.5.1.104 G Polysaccharide deacetylase
HCLKBIDA_02119 7.1e-129 S Glycosyltransferase like family
HCLKBIDA_02120 3.1e-203 S Sugar transport-related sRNA regulator N-term
HCLKBIDA_02121 9.5e-109 S Sugar transport-related sRNA regulator N-term
HCLKBIDA_02122 5.8e-225 EGP Major facilitator Superfamily
HCLKBIDA_02123 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HCLKBIDA_02124 2.6e-211 fadA 2.3.1.16 I Belongs to the thiolase family
HCLKBIDA_02125 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HCLKBIDA_02126 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HCLKBIDA_02127 1.2e-64 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HCLKBIDA_02128 6.3e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCLKBIDA_02129 1.4e-113 metI P COG2011 ABC-type metal ion transport system, permease component
HCLKBIDA_02130 9.7e-155 metQ P Belongs to the NlpA lipoprotein family
HCLKBIDA_02131 2.5e-95 S Cobalamin adenosyltransferase
HCLKBIDA_02132 4.8e-168 btuF P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HCLKBIDA_02133 6.4e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HCLKBIDA_02134 7.1e-144 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HCLKBIDA_02135 1.2e-244 O assembly protein SufD
HCLKBIDA_02136 2.5e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCLKBIDA_02137 5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HCLKBIDA_02138 7.4e-269 sufB O FeS cluster assembly
HCLKBIDA_02139 1.1e-242 aceA 4.1.3.1 C Isocitrate lyase
HCLKBIDA_02140 5.8e-17 S YhfH-like protein
HCLKBIDA_02141 1.7e-51 licT K transcriptional antiterminator
HCLKBIDA_02142 5.6e-28 3.2.1.86 GT1 G beta-glucosidase activity
HCLKBIDA_02143 3.8e-139 bioC_2 Q Methyltransferase domain
HCLKBIDA_02144 1.1e-186 gpr C Aldo/keto reductase family
HCLKBIDA_02145 1.5e-136 K AraC family transcriptional regulator
HCLKBIDA_02146 1.3e-171 P Periplasmic binding protein
HCLKBIDA_02147 1.2e-168 kka S Phosphotransferase enzyme family
HCLKBIDA_02148 4e-41 S Family of unknown function (DUF5344)
HCLKBIDA_02149 3.2e-161 S LXG domain of WXG superfamily
HCLKBIDA_02150 3e-38
HCLKBIDA_02151 5.4e-40
HCLKBIDA_02152 1.4e-40
HCLKBIDA_02153 2.5e-10
HCLKBIDA_02154 9.9e-157
HCLKBIDA_02155 1.9e-48
HCLKBIDA_02156 1.2e-64 S Domain of unknown function (DUF5082)
HCLKBIDA_02157 4.2e-166 yunF S Protein of unknown function DUF72
HCLKBIDA_02158 1e-140 yunE S membrane transporter protein
HCLKBIDA_02159 6.9e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HCLKBIDA_02160 1.2e-49 yunC S Domain of unknown function (DUF1805)
HCLKBIDA_02161 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCLKBIDA_02162 4.8e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCLKBIDA_02163 4.6e-140 yunB S Sporulation protein YunB (Spo_YunB)
HCLKBIDA_02164 3.7e-294 nhaC C Na+/H+ antiporter family
HCLKBIDA_02165 4.2e-205 lytH M Peptidase, M23
HCLKBIDA_02166 1.6e-174 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HCLKBIDA_02167 3.6e-94 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCLKBIDA_02168 3.7e-50 yutD S protein conserved in bacteria
HCLKBIDA_02169 6e-44
HCLKBIDA_02170 5.1e-78 yutE S Protein of unknown function DUF86
HCLKBIDA_02171 7.3e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCLKBIDA_02172 4.6e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HCLKBIDA_02173 1.5e-210 yutH S Spore coat protein
HCLKBIDA_02174 6.7e-238 hom 1.1.1.3 E homoserine dehydrogenase
HCLKBIDA_02175 8.9e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HCLKBIDA_02176 7e-164 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCLKBIDA_02177 9.7e-36 yutI O COG0694 Thioredoxin-like proteins and domains
HCLKBIDA_02178 4.3e-52 yuzD S protein conserved in bacteria
HCLKBIDA_02179 0.0 yutJ 1.6.99.3 C NADH dehydrogenase
HCLKBIDA_02180 7.6e-41 yuzB S Belongs to the UPF0349 family
HCLKBIDA_02181 1.4e-42
HCLKBIDA_02182 8.7e-164 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCLKBIDA_02183 6.7e-209 mqnE 1.21.98.1, 2.5.1.120, 2.5.1.77 H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HCLKBIDA_02184 7.6e-09 S Spo0E like sporulation regulatory protein
HCLKBIDA_02185 2.9e-60 erpA S Belongs to the HesB IscA family
HCLKBIDA_02186 3.3e-110 yecS P COG0765 ABC-type amino acid transport system, permease component
HCLKBIDA_02187 1.6e-154 yckB ET Belongs to the bacterial solute-binding protein 3 family
HCLKBIDA_02188 1.5e-308 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HCLKBIDA_02189 0.0 mtlR K transcriptional regulator, MtlR
HCLKBIDA_02190 4.7e-73 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HCLKBIDA_02191 1.7e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HCLKBIDA_02192 2.1e-185 ycgT 1.18.1.2, 1.19.1.1 C reductase
HCLKBIDA_02193 4.4e-230 yumB 1.6.99.3 C NADH dehydrogenase
HCLKBIDA_02194 1.5e-47 yuiB S Putative membrane protein
HCLKBIDA_02195 2.5e-112 yuiC S protein conserved in bacteria
HCLKBIDA_02196 7e-79 yuiD S protein conserved in bacteria
HCLKBIDA_02197 1.2e-282 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HCLKBIDA_02198 2.7e-45
HCLKBIDA_02199 1.8e-232 S antiporter
HCLKBIDA_02200 1.9e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCLKBIDA_02201 6.1e-146 yihY S Belongs to the UPF0761 family
HCLKBIDA_02202 1.1e-86 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCLKBIDA_02203 3.1e-84 alaR K Transcriptional regulator
HCLKBIDA_02204 3.9e-223 yugH 2.6.1.1 E Aminotransferase
HCLKBIDA_02205 1.7e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCLKBIDA_02206 1.6e-205 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HCLKBIDA_02207 4.2e-52 J RNA binding protein (contains ribosomal protein S1 domain)
HCLKBIDA_02208 1.2e-33 yuzA S Domain of unknown function (DUF378)
HCLKBIDA_02209 3.1e-228 yugK C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HCLKBIDA_02210 8.3e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HCLKBIDA_02211 3.5e-260 pgi 5.3.1.9 G Belongs to the GPI family
HCLKBIDA_02212 2.5e-71 yugN S YugN-like family
HCLKBIDA_02213 2.7e-21
HCLKBIDA_02215 6.3e-104 L Phage integrase, N-terminal SAM-like domain
HCLKBIDA_02220 3.3e-73 V HNH endonuclease
HCLKBIDA_02221 6e-37 L phage terminase small subunit
HCLKBIDA_02222 6.1e-249 S Terminase
HCLKBIDA_02223 9e-27
HCLKBIDA_02224 6.8e-245 S Phage portal protein
HCLKBIDA_02225 7.3e-115 pi136 S Caudovirus prohead serine protease
HCLKBIDA_02226 4.6e-230 gp36 S capsid protein
HCLKBIDA_02227 7.7e-48 N Bacterial Ig-like domain 2
HCLKBIDA_02228 8e-48 S Phage gp6-like head-tail connector protein
HCLKBIDA_02229 9.5e-56 S Phage head-tail joining protein
HCLKBIDA_02230 4.5e-17 S Bacteriophage HK97-gp10, putative tail-component
HCLKBIDA_02231 1e-52
HCLKBIDA_02232 3.7e-108 N phage major tail protein, phi13 family
HCLKBIDA_02233 5.6e-08
HCLKBIDA_02235 0.0 D phage tail tape measure protein
HCLKBIDA_02236 2.8e-154 S Phage tail protein
HCLKBIDA_02237 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
HCLKBIDA_02238 0.0
HCLKBIDA_02241 4e-08
HCLKBIDA_02242 1.2e-197 L Prophage endopeptidase tail
HCLKBIDA_02243 1.2e-62 S Bacteriophage holin family
HCLKBIDA_02244 2.3e-146 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCLKBIDA_02246 2.9e-148 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HCLKBIDA_02247 6.1e-58 S YolD-like protein
HCLKBIDA_02248 2.1e-25
HCLKBIDA_02251 2.8e-84 E Zn peptidase
HCLKBIDA_02252 7e-46 K Helix-turn-helix XRE-family like proteins
HCLKBIDA_02253 6e-25
HCLKBIDA_02255 6.3e-51
HCLKBIDA_02257 4.7e-20
HCLKBIDA_02258 9.4e-95 S Bacteriophage Mu Gam like protein
HCLKBIDA_02259 1.1e-170 tadZ D AAA domain
HCLKBIDA_02260 3.1e-59 S Protein of unknown function (DUF669)
HCLKBIDA_02261 0.0 S D5 N terminal like
HCLKBIDA_02262 9.5e-74
HCLKBIDA_02263 1.1e-95 L ERCC4 domain
HCLKBIDA_02264 1.1e-22
HCLKBIDA_02266 1.4e-35 S Protein of unknwon function (DUF3310)
HCLKBIDA_02273 1.9e-24
HCLKBIDA_02274 8.2e-52 S Transcriptional regulator
HCLKBIDA_02275 3.1e-07 yeaO S Protein of unknown function, DUF488
HCLKBIDA_02276 3.8e-168 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HCLKBIDA_02277 8.7e-165 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HCLKBIDA_02278 8.9e-84 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HCLKBIDA_02279 2.9e-58 S Protein of unknown function (DUF1516)
HCLKBIDA_02280 2.6e-82 S DinB superfamily
HCLKBIDA_02281 1.5e-77 S Putative small multi-drug export protein
HCLKBIDA_02282 8.8e-238 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCLKBIDA_02283 1.2e-106 pgpB3 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HCLKBIDA_02284 4.8e-163 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCLKBIDA_02285 1.4e-154 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCLKBIDA_02286 4.5e-149 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HCLKBIDA_02287 1e-176 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HCLKBIDA_02288 1.8e-107 mrr V Restriction endonuclease
HCLKBIDA_02289 8.2e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HCLKBIDA_02290 1.1e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HCLKBIDA_02291 1.3e-223 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HCLKBIDA_02293 7.9e-85 ywpF S YwpF-like protein
HCLKBIDA_02294 3.7e-224 ymfD EGP Major facilitator Superfamily
HCLKBIDA_02295 8.3e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HCLKBIDA_02296 5.9e-138 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCLKBIDA_02297 2.1e-137 ytlC P ABC transporter
HCLKBIDA_02298 3.1e-181 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HCLKBIDA_02299 8.3e-153 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HCLKBIDA_02300 6.6e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HCLKBIDA_02301 6.1e-227 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCLKBIDA_02302 2e-68 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HCLKBIDA_02303 1.7e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
HCLKBIDA_02304 2.6e-106 4.2.1.1 P Reversible hydration of carbon dioxide
HCLKBIDA_02305 3.5e-103 ytqB J Putative rRNA methylase
HCLKBIDA_02307 8.3e-45 UW Collagen triple helix repeat (20 copies)
HCLKBIDA_02308 2.6e-121 ycbG K FCD
HCLKBIDA_02309 4.5e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HCLKBIDA_02310 1.4e-259 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCLKBIDA_02311 2.1e-83 S Tripartite tricarboxylate transporter TctB family
HCLKBIDA_02312 5.3e-265 S Tripartite tricarboxylate transporter TctA family
HCLKBIDA_02313 9.1e-192 S Tripartite tricarboxylate transporter family receptor
HCLKBIDA_02314 7.2e-189 uxuA 4.2.1.8 G mannonate dehydratase activity
HCLKBIDA_02315 7.2e-53
HCLKBIDA_02316 0.0
HCLKBIDA_02317 1.4e-130
HCLKBIDA_02318 1.6e-67 3.6.1.55 F NUDIX domain
HCLKBIDA_02319 4.8e-99 S Tetratricopeptide repeat
HCLKBIDA_02320 1.6e-239 V MatE
HCLKBIDA_02321 1.7e-254 NT chemotaxis protein
HCLKBIDA_02322 5.8e-228 C Citrate transporter
HCLKBIDA_02323 3e-53
HCLKBIDA_02324 8.4e-238 E Acyclic terpene utilisation family protein AtuA
HCLKBIDA_02325 1.4e-256 KT Transcriptional regulator
HCLKBIDA_02326 3.1e-104 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HCLKBIDA_02327 2e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HCLKBIDA_02328 9.6e-269 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCLKBIDA_02330 3.6e-96 5.3.1.15 S Cupin 2, conserved barrel domain protein
HCLKBIDA_02331 1.1e-166 fruA2 G Phosphotransferase System
HCLKBIDA_02332 1.1e-47 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HCLKBIDA_02333 1.5e-77 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCLKBIDA_02334 2.3e-159 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HCLKBIDA_02335 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 K transcriptional regulator, MtlR
HCLKBIDA_02336 4.7e-293 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HCLKBIDA_02337 2.4e-289 uxaA 4.2.1.7 G Altronate
HCLKBIDA_02338 3.3e-223 G Tripartite ATP-independent periplasmic transporter, DctM component
HCLKBIDA_02339 1.6e-82 G Tripartite ATP-independent periplasmic transporters, DctQ component
HCLKBIDA_02340 4.2e-189 dctP G Bacterial extracellular solute-binding protein, family 7
HCLKBIDA_02341 2.5e-194 yjjN E Alcohol dehydrogenase GroES-like domain
HCLKBIDA_02342 1.1e-161 K AraC-like ligand binding domain
HCLKBIDA_02343 8.4e-251 bxlD G Bacterial extracellular solute-binding protein
HCLKBIDA_02344 1.7e-165 bxlC G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02345 2.4e-142 bxlB G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02346 1.4e-64 S Putative zinc- or iron-chelating domain
HCLKBIDA_02347 8.1e-246 metY 2.5.1.49 E O-acetylhomoserine
HCLKBIDA_02348 3.3e-104 S Protein of unknown function (DUF421)
HCLKBIDA_02349 4.7e-272 yidK S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HCLKBIDA_02350 5.9e-191 yisS 1.1.1.370 S Oxidoreductase family, NAD-binding Rossmann fold
HCLKBIDA_02351 4.5e-163 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HCLKBIDA_02352 3.6e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HCLKBIDA_02353 1.3e-178 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HCLKBIDA_02354 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HCLKBIDA_02355 3.4e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HCLKBIDA_02356 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HCLKBIDA_02357 4.7e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCLKBIDA_02358 2.2e-137 iolR K COG1349 Transcriptional regulators of sugar metabolism
HCLKBIDA_02359 5.7e-245 EGP Major Facilitator Superfamily
HCLKBIDA_02360 2.3e-99 yvdT K Transcriptional regulator
HCLKBIDA_02361 3.2e-59 sugE P Small Multidrug Resistance protein
HCLKBIDA_02362 2.2e-48 sugE P Small Multidrug Resistance protein
HCLKBIDA_02363 9.7e-183 KTV LytTr DNA-binding domain
HCLKBIDA_02364 2.6e-113 V Transport permease protein
HCLKBIDA_02365 2.4e-81 S Putative small multi-drug export protein
HCLKBIDA_02366 2.4e-26
HCLKBIDA_02367 2e-51 V ATPases associated with a variety of cellular activities
HCLKBIDA_02370 1.8e-300 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HCLKBIDA_02371 1.1e-198 gguB G Belongs to the binding-protein-dependent transport system permease family
HCLKBIDA_02372 7.3e-286 araG 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HCLKBIDA_02373 2.3e-198 chvE G ABC transporter
HCLKBIDA_02374 2.2e-287 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HCLKBIDA_02375 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HCLKBIDA_02376 7.5e-137 araD 4.1.2.17, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HCLKBIDA_02377 9.4e-217 egsA 1.1.1.261 C Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HCLKBIDA_02378 2.3e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HCLKBIDA_02379 6.6e-170 rhaR1 K AraC-like ligand binding domain
HCLKBIDA_02380 2.4e-175 M1-640 K Transcriptional regulator
HCLKBIDA_02381 5.9e-109 S Protein of unknown function, DUF624
HCLKBIDA_02382 6.8e-153 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02383 3e-159 amyD G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02384 1.1e-242 G Bacterial extracellular solute-binding protein
HCLKBIDA_02385 1.7e-303 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HCLKBIDA_02386 7.8e-157 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02387 2.5e-148 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02388 3.3e-239 G Bacterial extracellular solute-binding protein
HCLKBIDA_02389 0.0 E cell wall organization
HCLKBIDA_02391 5.2e-127 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
HCLKBIDA_02392 2.8e-160 K LysR substrate binding domain
HCLKBIDA_02393 1.1e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_02394 3.2e-237 arlS T His Kinase A (phosphoacceptor) domain
HCLKBIDA_02395 4.4e-200 I Acyltransferase family
HCLKBIDA_02396 8.6e-156 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02397 1.1e-175 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02398 5.3e-253 G Bacterial extracellular solute-binding protein
HCLKBIDA_02399 2.8e-207 T helix_turn_helix, arabinose operon control protein
HCLKBIDA_02400 0.0 2.7.13.3 T Histidine kinase
HCLKBIDA_02401 6.3e-226 S Oxidoreductase family, NAD-binding Rossmann fold
HCLKBIDA_02402 6.2e-159 MA20_16875 G Xylose isomerase-like TIM barrel
HCLKBIDA_02403 1.1e-222 MA20_16880 EM Protein of unknown function (DUF993)
HCLKBIDA_02404 9.3e-233 MA20_16885 S Oxidoreductase family, NAD-binding Rossmann fold
HCLKBIDA_02405 1e-148 K AraC-like ligand binding domain
HCLKBIDA_02406 1.7e-227 iolF EGP Major facilitator Superfamily
HCLKBIDA_02407 5.1e-53 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HCLKBIDA_02408 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HCLKBIDA_02409 0.0 rhaA 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HCLKBIDA_02410 2.4e-181 K AraC-like ligand binding domain
HCLKBIDA_02411 9.8e-261 yhdG E amino acid
HCLKBIDA_02412 4.9e-173 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HCLKBIDA_02413 1.8e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCLKBIDA_02414 4.5e-157 K helix_turn_helix, arabinose operon control protein
HCLKBIDA_02415 4.6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_02416 6.5e-186
HCLKBIDA_02417 3.7e-105 ykoP G polysaccharide deacetylase
HCLKBIDA_02419 1.1e-187 V COG0842 ABC-type multidrug transport system, permease component
HCLKBIDA_02420 5.5e-220 V COG0842 ABC-type multidrug transport system, permease component
HCLKBIDA_02421 8e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
HCLKBIDA_02422 1.1e-107 KT LuxR family transcriptional regulator
HCLKBIDA_02423 6.8e-201 yxjM T Signal transduction histidine kinase
HCLKBIDA_02424 1.2e-91 ttr K GCN5 family acetyltransferase
HCLKBIDA_02425 1.2e-153 fhuD P Periplasmic binding protein
HCLKBIDA_02426 4.7e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_02427 6.3e-233 gntT EG COG2610 H gluconate symporter and related permeases
HCLKBIDA_02428 9.2e-200 gutB 1.1.1.14 E Dehydrogenase
HCLKBIDA_02429 1.6e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_02430 2.7e-188 K helix_turn _helix lactose operon repressor
HCLKBIDA_02431 2.8e-202 cpg2 3.4.17.11 E Peptidase dimerisation domain
HCLKBIDA_02432 1.6e-238 purD 6.3.4.13 F Belongs to the GARS family
HCLKBIDA_02433 1.1e-284 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HCLKBIDA_02434 2.3e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCLKBIDA_02435 1.9e-192 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HCLKBIDA_02436 5.5e-272 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCLKBIDA_02437 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCLKBIDA_02438 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCLKBIDA_02439 1.4e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCLKBIDA_02440 6.5e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HCLKBIDA_02441 9.3e-250 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCLKBIDA_02442 6.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCLKBIDA_02443 3.1e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCLKBIDA_02444 1.8e-128 S CAAX protease self-immunity
HCLKBIDA_02445 5.6e-103 rimL 1.1.1.25 J Acetyltransferase (GNAT) domain
HCLKBIDA_02446 2.6e-64 S PFAM AIG2 family protein
HCLKBIDA_02447 3.1e-110
HCLKBIDA_02448 2.3e-68 S Calcium/calmodulin dependent protein kinase II association domain
HCLKBIDA_02449 1.1e-30 yebG S NETI protein
HCLKBIDA_02450 2e-16 repB L Initiator Replication protein
HCLKBIDA_02451 5.5e-262 tctA S Tripartite tricarboxylate transporter TctA family
HCLKBIDA_02452 2.6e-74 S Tripartite tricarboxylate transporter TctB family
HCLKBIDA_02453 3.8e-190 S Tripartite tricarboxylate transporter family receptor
HCLKBIDA_02455 6.7e-111 citT T response regulator
HCLKBIDA_02456 3.2e-284 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HCLKBIDA_02457 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HCLKBIDA_02458 2.6e-20 fliA K sigma factor activity
HCLKBIDA_02459 2.4e-19 S YvrJ protein family
HCLKBIDA_02460 2e-140
HCLKBIDA_02461 3.7e-54 K Transcriptional regulator PadR-like family
HCLKBIDA_02462 3.1e-148
HCLKBIDA_02464 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCLKBIDA_02465 6.3e-310 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCLKBIDA_02467 3.8e-235 G Major facilitator Superfamily
HCLKBIDA_02468 2.6e-21
HCLKBIDA_02470 2.7e-97 ypbQ S protein conserved in bacteria
HCLKBIDA_02471 8e-210 bcsA Q Naringenin-chalcone synthase
HCLKBIDA_02472 3.9e-131 mta K transcriptional
HCLKBIDA_02473 1.5e-117 rimJ2 J Acetyltransferase (GNAT) domain
HCLKBIDA_02474 2.7e-279 uxaC 5.3.1.12 G glucuronate isomerase
HCLKBIDA_02475 5.2e-161 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HCLKBIDA_02476 3.4e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_02477 1.7e-134 xytR K DeoR C terminal sensor domain
HCLKBIDA_02478 4.5e-89 ywrA P COG2059 Chromate transport protein ChrA
HCLKBIDA_02479 5.2e-107 ywrB P COG2059 Chromate transport protein ChrA
HCLKBIDA_02480 2.6e-160 mqnD S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HCLKBIDA_02481 2.3e-114 mqnB 2.4.2.1, 3.2.2.26, 3.2.2.9 F Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
HCLKBIDA_02482 7.9e-282 lipA1 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HCLKBIDA_02483 5.4e-286 K transcriptional antiterminator
HCLKBIDA_02484 3.4e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HCLKBIDA_02485 0.0 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HCLKBIDA_02486 1.7e-166 Q calcium- and calmodulin-responsive adenylate cyclase activity
HCLKBIDA_02487 3.2e-158 proX E Substrate binding domain of ABC-type glycine betaine transport system
HCLKBIDA_02488 4.1e-101 K Belongs to the GbsR family
HCLKBIDA_02489 1.6e-277 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HCLKBIDA_02490 3.8e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HCLKBIDA_02491 1.2e-138 yvfI K COG2186 Transcriptional regulators
HCLKBIDA_02492 2.6e-126 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HCLKBIDA_02493 9.2e-275 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HCLKBIDA_02494 5.9e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HCLKBIDA_02495 0.0 lldP C L-lactate permease
HCLKBIDA_02496 4.8e-15
HCLKBIDA_02497 3.4e-230 cypA C Cytochrome P450
HCLKBIDA_02498 4.9e-274 ydaH H AbgT putative transporter family
HCLKBIDA_02499 0.0 htpG O Molecular chaperone. Has ATPase activity
HCLKBIDA_02500 5.6e-103 yaaI Q Isochorismatase family
HCLKBIDA_02501 4.4e-77 ygaO
HCLKBIDA_02502 5.4e-27 K Transcriptional regulator
HCLKBIDA_02503 0.0 sasH 3.1.3.5, 3.6.1.45 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HCLKBIDA_02505 2.8e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HCLKBIDA_02506 9.2e-289 prdR KT Transcriptional regulator
HCLKBIDA_02507 9.4e-172 putA E Proline dehydrogenase
HCLKBIDA_02508 2.1e-151 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HCLKBIDA_02509 2.2e-74 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HCLKBIDA_02510 1.1e-308 S proteins of the AP superfamily
HCLKBIDA_02512 8.5e-211 pbuG S permease
HCLKBIDA_02513 2.8e-69
HCLKBIDA_02514 4.2e-180 aph 2.7.11.1 S Phosphotransferase enzyme family
HCLKBIDA_02515 4e-218 G Transmembrane secretion effector
HCLKBIDA_02516 3.1e-24 S YfhD-like protein
HCLKBIDA_02517 1.9e-65 dhaM 2.7.1.121 S PTS system fructose IIA component
HCLKBIDA_02518 5.8e-109 dhaL 2.7.1.121 S Dak2
HCLKBIDA_02519 5.5e-178 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
HCLKBIDA_02520 3.2e-88 M1-431 S Protein of unknown function (DUF1706)
HCLKBIDA_02521 3.5e-74 adcR K Iron dependent repressor, N-terminal DNA binding domain
HCLKBIDA_02522 3.6e-200 yvmA EGP Major Facilitator Superfamily
HCLKBIDA_02523 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCLKBIDA_02524 5e-232 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
HCLKBIDA_02525 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
HCLKBIDA_02526 1.5e-184 yxeA V FtsX-like permease family
HCLKBIDA_02527 6.3e-117 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
HCLKBIDA_02528 5.4e-79 K Bacterial regulatory proteins, tetR family
HCLKBIDA_02529 8.4e-176 S Erythromycin esterase
HCLKBIDA_02530 9.6e-32 S Sporulation inhibitor A
HCLKBIDA_02531 6.6e-158 chiA 3.2.1.14, 3.2.1.17 AA10,CBM15,CBM73,GH18 D Lytic polysaccharide mono-oxygenase, cellulose-degrading
HCLKBIDA_02532 1.7e-142 C KR domain
HCLKBIDA_02533 1.7e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HCLKBIDA_02534 1.1e-178 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
HCLKBIDA_02535 1e-99 srlA G PTS system enzyme II sorbitol-specific factor
HCLKBIDA_02536 4.7e-76 gutM K Glucitol operon activator
HCLKBIDA_02537 2.4e-173 sorC K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HCLKBIDA_02538 4.2e-291 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HCLKBIDA_02539 3.8e-287 uxaA 4.2.1.7 G Altronate
HCLKBIDA_02540 3.4e-252 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_02541 8.1e-123 S Integral membrane protein
HCLKBIDA_02542 1.2e-80 G carbohydrate transport
HCLKBIDA_02543 3.7e-223 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HCLKBIDA_02544 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
HCLKBIDA_02545 8.1e-171 E Abhydrolase family
HCLKBIDA_02546 3.4e-155 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02547 1.3e-179 G COG4209 ABC-type polysaccharide transport system, permease component
HCLKBIDA_02548 4.1e-297 G ABC transporter substrate-binding protein
HCLKBIDA_02549 0.0 K Transcriptional regulator
HCLKBIDA_02550 6.4e-162 3.2.2.21 K AraC-like ligand binding domain
HCLKBIDA_02551 2.4e-200 pelE 3.4.11.10, 3.4.11.6, 4.2.2.2 M Pectic acid lyase
HCLKBIDA_02552 9.6e-109 J Acetyltransferase (GNAT) domain
HCLKBIDA_02553 1.7e-131 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HCLKBIDA_02554 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
HCLKBIDA_02555 0.0 lplA7 G Bacterial extracellular solute-binding protein
HCLKBIDA_02556 4.3e-169 lplC1 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02557 6.4e-179 lplB P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02558 2.1e-282 araC7 T helix_turn_helix, arabinose operon control protein
HCLKBIDA_02559 0.0 2.7.13.3 T Histidine kinase
HCLKBIDA_02560 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
HCLKBIDA_02561 1.2e-211 glcP G Major Facilitator Superfamily
HCLKBIDA_02562 5.2e-192 xylR3 2.7.1.2 GK ROK family
HCLKBIDA_02563 1.8e-278 M1-1044 S Belongs to the UPF0061 (SELO) family
HCLKBIDA_02564 8.4e-218 uxaA 4.2.1.7 G D-galactarate dehydratase / Altronate hydrolase, C terminus
HCLKBIDA_02565 2.3e-47 uxaA 4.2.1.7 G SAF
HCLKBIDA_02566 3e-216 G Tripartite ATP-independent periplasmic transporter, DctM component
HCLKBIDA_02567 1.3e-90 G Tripartite ATP-independent periplasmic transporters, DctQ component
HCLKBIDA_02568 1.8e-195 dctP G Bacterial extracellular solute-binding protein, family 7
HCLKBIDA_02569 4.8e-162 K AraC-like ligand binding domain
HCLKBIDA_02570 1.9e-169 Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HCLKBIDA_02571 4.7e-139 ygaJ E Belongs to the peptidase S51 family
HCLKBIDA_02572 2.9e-164 S Alpha beta hydrolase
HCLKBIDA_02574 2.5e-175 yjiA S Cobalamin biosynthesis protein CobW
HCLKBIDA_02575 3.4e-191 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HCLKBIDA_02576 6.6e-258 adcA P Zinc-uptake complex component A periplasmic
HCLKBIDA_02577 2.1e-134 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HCLKBIDA_02578 8.5e-132 adcB P ABC 3 transport family
HCLKBIDA_02579 8.3e-271 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCLKBIDA_02580 4.8e-168 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
HCLKBIDA_02581 4.7e-165 MA20_14845 4.2.1.141 S Fumarylacetoacetate (FAA) hydrolase family
HCLKBIDA_02582 6.5e-142 K helix_turn_helix isocitrate lyase regulation
HCLKBIDA_02583 0.0 yjhG 4.2.1.82 EG Dehydratase family
HCLKBIDA_02584 7.2e-243 yjhF EG COG2610 H gluconate symporter and related permeases
HCLKBIDA_02585 5.9e-32 K MerR family transcriptional regulator
HCLKBIDA_02586 8.7e-139 IQ Enoyl-(Acyl carrier protein) reductase
HCLKBIDA_02587 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCLKBIDA_02588 1.7e-209 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
HCLKBIDA_02589 4.4e-43 ulaB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
HCLKBIDA_02590 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
HCLKBIDA_02591 5.5e-104
HCLKBIDA_02592 5.2e-267 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCLKBIDA_02593 3.2e-80 fld C Flavodoxin
HCLKBIDA_02594 7.1e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HCLKBIDA_02595 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCLKBIDA_02596 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCLKBIDA_02597 1.8e-44 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCLKBIDA_02598 5.6e-91 yizA S DinB family
HCLKBIDA_02599 1.3e-179
HCLKBIDA_02601 1.4e-157 yufQ S Belongs to the binding-protein-dependent transport system permease family
HCLKBIDA_02602 1.5e-189 yufP S Belongs to the binding-protein-dependent transport system permease family
HCLKBIDA_02603 3.4e-283 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HCLKBIDA_02604 5e-204 bmpA S ABC-type transport system, periplasmic component surface lipoprotein
HCLKBIDA_02605 1.5e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
HCLKBIDA_02606 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCLKBIDA_02607 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HCLKBIDA_02608 8.3e-131 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HCLKBIDA_02609 6.7e-153 fhuC 3.6.3.34 HP ABC transporter
HCLKBIDA_02610 3.8e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCLKBIDA_02611 5.9e-178 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCLKBIDA_02613 2.3e-26 mepA V MATE efflux family protein
HCLKBIDA_02614 3.2e-169 lacX G Aldose 1-epimerase
HCLKBIDA_02615 0.0 acyII 3.5.1.11, 3.5.1.97 S Penicillin amidase
HCLKBIDA_02616 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HCLKBIDA_02617 6.8e-32
HCLKBIDA_02619 1.2e-49 yerC S protein conserved in bacteria
HCLKBIDA_02620 0.0 3.5.4.2 F adenine deaminase
HCLKBIDA_02621 6e-199 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HCLKBIDA_02623 1.4e-159 opuAC E glycine betaine
HCLKBIDA_02624 3e-148 proW P glycine betaine
HCLKBIDA_02625 9.4e-220 gbuA 3.6.3.32 E glycine betaine
HCLKBIDA_02626 2.2e-96 K Belongs to the GbsR family
HCLKBIDA_02628 3.8e-18
HCLKBIDA_02629 6.2e-21
HCLKBIDA_02630 4.3e-68
HCLKBIDA_02631 1.4e-133 S GNAT acetyltransferase
HCLKBIDA_02632 1.3e-199 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCLKBIDA_02634 6.4e-243 M Peptidoglycan-binding domain 1 protein
HCLKBIDA_02636 0.0 2.7.13.3 T Histidine kinase
HCLKBIDA_02638 0.0
HCLKBIDA_02639 1.3e-119 lolD V ABC transporter
HCLKBIDA_02640 1.2e-305 sdcS P Sodium:sulfate symporter transmembrane region
HCLKBIDA_02641 4e-122 T COG4565 Response regulator of citrate malate metabolism
HCLKBIDA_02642 6.2e-304 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HCLKBIDA_02643 1.7e-119 idi I COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HCLKBIDA_02644 2.9e-176 rihB 3.2.2.1 F nucleoside hydrolase
HCLKBIDA_02645 2e-61 S CHY zinc finger
HCLKBIDA_02646 2e-236 braB E Component of the transport system for branched-chain amino acids
HCLKBIDA_02647 4.7e-88 sdpI S integral membrane protein
HCLKBIDA_02648 4.5e-225 EGP Major facilitator Superfamily
HCLKBIDA_02649 3.2e-106 GBS0088 S protein conserved in bacteria
HCLKBIDA_02650 5.2e-147 ubiE Q Methyltransferase type 11
HCLKBIDA_02651 3.4e-239 S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HCLKBIDA_02652 3.1e-46 phhB 3.5.4.33, 4.2.1.96 H pterin-4-alpha-carbinolamine dehydratase
HCLKBIDA_02653 7.8e-67 eaeH M LysM domain
HCLKBIDA_02654 4.4e-71 S YtkA-like
HCLKBIDA_02655 2.4e-259 T Histidine kinase
HCLKBIDA_02656 2.3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_02657 2.1e-177 S amine dehydrogenase activity
HCLKBIDA_02658 4.4e-195 P COG2807 Cyanate permease
HCLKBIDA_02660 7e-33
HCLKBIDA_02661 2.3e-09
HCLKBIDA_02662 9.9e-118 M1-1017 S Protein of unknown function (DUF1129)
HCLKBIDA_02663 2.8e-57 K Transcriptional regulator
HCLKBIDA_02665 2e-109 S DUF218 domain
HCLKBIDA_02666 7.9e-149 degV S protein conserved in bacteria
HCLKBIDA_02667 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCLKBIDA_02668 2.5e-40 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCLKBIDA_02669 2.2e-229 yciC S GTPases (G3E family)
HCLKBIDA_02670 9e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HCLKBIDA_02671 4.8e-07
HCLKBIDA_02672 2.5e-21
HCLKBIDA_02675 6.9e-189 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HCLKBIDA_02676 0.0 ubiD 4.1.1.98 H Belongs to the UbiD family
HCLKBIDA_02677 2.8e-114 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HCLKBIDA_02678 5.6e-132 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HCLKBIDA_02679 1.2e-241 atoE I Short chain fatty acid transporter
HCLKBIDA_02680 5.6e-189 malR 5.1.1.1 K Transcriptional regulator
HCLKBIDA_02681 3.5e-149 malG P transport
HCLKBIDA_02682 3e-248 malC P COG1175 ABC-type sugar transport systems, permease components
HCLKBIDA_02683 8.4e-243 G COG2182 Maltose-binding periplasmic proteins domains
HCLKBIDA_02684 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HCLKBIDA_02686 1.3e-245 codA 3.5.4.1 F Amidohydrolase family
HCLKBIDA_02687 1.3e-221 codB F cytosine purines uracil thiamine allantoin
HCLKBIDA_02689 1.8e-287 QT COG2508 Regulator of polyketide synthase expression
HCLKBIDA_02690 1.8e-223 lhgO 1.1.99.2 S FAD dependent oxidoreductase
HCLKBIDA_02691 3.1e-253 glcF C Glycolate oxidase
HCLKBIDA_02692 5.9e-266 glcD 1.1.3.15 C Glycolate oxidase subunit
HCLKBIDA_02693 2.4e-122 K COG2186 Transcriptional regulators
HCLKBIDA_02694 7.6e-121 K FCD
HCLKBIDA_02695 0.0 S Tripartite ATP-independent periplasmic transporter, DctM component
HCLKBIDA_02696 5.5e-186 S NMT1-like family
HCLKBIDA_02697 5.4e-161 K Transcriptional regulator
HCLKBIDA_02698 8.5e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
HCLKBIDA_02699 3.5e-209 siaM G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HCLKBIDA_02700 1.3e-76 G Tripartite ATP-independent periplasmic transporters, DctQ component
HCLKBIDA_02701 4.5e-183 G Bacterial extracellular solute-binding protein, family 7
HCLKBIDA_02702 1.6e-115 K FCD
HCLKBIDA_02703 6.2e-196 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HCLKBIDA_02704 2.3e-263 NT chemotaxis protein
HCLKBIDA_02705 1.1e-89 paiA K Acetyltransferase (GNAT) domain
HCLKBIDA_02706 5.8e-97 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HCLKBIDA_02707 4.1e-184 S Domain of unknown function (DUF4179)
HCLKBIDA_02708 3.8e-75 S Domain of unknown function (DU1801)
HCLKBIDA_02709 1e-113 S CGNR zinc finger
HCLKBIDA_02710 1.8e-83
HCLKBIDA_02711 4.5e-269 cstA T Carbon starvation protein
HCLKBIDA_02712 3.6e-134 T COG3279 Response regulator of the LytR AlgR family
HCLKBIDA_02713 0.0 lytS 2.7.13.3 T Histidine kinase
HCLKBIDA_02714 1.6e-105 K Transcriptional regulator
HCLKBIDA_02715 0.0 ydfJ S MMPL family
HCLKBIDA_02716 1.2e-186 S domain protein
HCLKBIDA_02717 3.9e-184 oppF3 E Belongs to the ABC transporter superfamily
HCLKBIDA_02718 1.1e-181 oppD3 P Belongs to the ABC transporter superfamily
HCLKBIDA_02719 4.1e-167 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_02720 1.2e-172 appB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_02721 0.0 oppA5 E Bacterial extracellular solute-binding proteins, family 5 Middle
HCLKBIDA_02723 1.5e-133 Z012_10580 S Sulfite exporter TauE/SafE
HCLKBIDA_02725 4.6e-112 S ABC-2 family transporter protein
HCLKBIDA_02726 1e-151 V ABC transporter
HCLKBIDA_02728 2.2e-122 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HCLKBIDA_02729 2.1e-209 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HCLKBIDA_02730 5e-74 siaT_3 G Tripartite ATP-independent periplasmic transporters, DctQ component
HCLKBIDA_02731 5.7e-183 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HCLKBIDA_02732 2.1e-188 1.1.1.14 E Dehydrogenase
HCLKBIDA_02733 2e-109 K FCD domain
HCLKBIDA_02734 7.1e-245 S Putative nucleotide-binding of sugar-metabolising enzyme
HCLKBIDA_02735 0.0 hsdR 3.1.21.3 L DEAD DEAH box helicase
HCLKBIDA_02736 2.4e-76 hsdS_2 3.1.21.3 V Type I restriction modification DNA specificity domain
HCLKBIDA_02737 1.7e-239 hsdM 2.1.1.72 V HsdM N-terminal domain
HCLKBIDA_02738 2.4e-155 S SIR2-like domain
HCLKBIDA_02739 3.5e-276 S Domain of unknown function DUF87
HCLKBIDA_02740 9.8e-307 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HCLKBIDA_02741 0.0 yebA E COG1305 Transglutaminase-like enzymes
HCLKBIDA_02742 1.4e-217 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HCLKBIDA_02743 8.9e-173 yeaC S COG0714 MoxR-like ATPases
HCLKBIDA_02744 4.8e-102 CO Thioredoxin
HCLKBIDA_02745 2.6e-185 3.1.4.53 Q Calcineurin-like phosphoesterase
HCLKBIDA_02748 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HCLKBIDA_02749 6e-108 C nitroreductase
HCLKBIDA_02750 9.4e-117 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCLKBIDA_02751 2.9e-76 S Bacteriophage holin family
HCLKBIDA_02753 0.0 L Phage minor structural protein
HCLKBIDA_02754 3.4e-137 S Phage tail protein
HCLKBIDA_02755 1.4e-118 D Phage tail tape measure protein, TP901 family
HCLKBIDA_02756 2.8e-76
HCLKBIDA_02757 8.2e-70
HCLKBIDA_02758 1.6e-53 S Short C-terminal domain
HCLKBIDA_02759 1.1e-212 mez_1 1.1.1.38 C Malate dehydrogenase
HCLKBIDA_02760 2.3e-243 maeN C COG3493 Na citrate symporter
HCLKBIDA_02761 1.3e-101 dcuR T COG4565 Response regulator of citrate malate metabolism
HCLKBIDA_02762 6.5e-261 malK 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HCLKBIDA_02763 1.3e-72 wecC 1.1.1.336 M ArpU family transcriptional regulator
HCLKBIDA_02764 2.6e-149 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCLKBIDA_02765 4e-119 ehuD E Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02766 5.5e-113 ehuC E Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02767 2e-149 ehuB ET Bacterial periplasmic substrate-binding proteins
HCLKBIDA_02768 6.2e-146
HCLKBIDA_02769 1.6e-154 S Haloacid dehalogenase-like hydrolase
HCLKBIDA_02770 3.6e-182 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCLKBIDA_02771 6.2e-70 wxcN GT2 S GtrA-like protein
HCLKBIDA_02772 0.0 yfhO S Bacterial membrane protein YfhO
HCLKBIDA_02775 1.1e-86 MA20_19235 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HCLKBIDA_02776 9.4e-138 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HCLKBIDA_02777 1.2e-109 yjgD S Protein of unknown function (DUF1641)
HCLKBIDA_02778 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HCLKBIDA_02779 1.9e-144 focA P Formate/nitrite transporter
HCLKBIDA_02780 5.7e-36 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HCLKBIDA_02781 1.1e-74 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HCLKBIDA_02782 4.5e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HCLKBIDA_02783 2.9e-243 moeA 2.10.1.1 H molybdopterin
HCLKBIDA_02784 1.8e-187 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HCLKBIDA_02785 1.9e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HCLKBIDA_02786 1.4e-104 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HCLKBIDA_02787 9.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HCLKBIDA_02788 2.5e-272 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HCLKBIDA_02789 3.2e-152 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCLKBIDA_02790 7.4e-121 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HCLKBIDA_02791 2.9e-131 S carbohydrate derivative metabolic process
HCLKBIDA_02792 1.1e-223 ulaA S PTS system ascorbate-specific transporter subunit IIC
HCLKBIDA_02793 1.4e-41 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
HCLKBIDA_02794 4.8e-73 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCLKBIDA_02795 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
HCLKBIDA_02796 6.4e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCLKBIDA_02797 5.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCLKBIDA_02798 2.3e-117 ydiL S CAAX protease self-immunity
HCLKBIDA_02800 3.4e-205 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HCLKBIDA_02801 1.3e-151 P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
HCLKBIDA_02802 2.7e-112 metI P COG2011 ABC-type metal ion transport system, permease component
HCLKBIDA_02803 2.2e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCLKBIDA_02804 3.6e-130 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HCLKBIDA_02805 1.4e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HCLKBIDA_02806 2.3e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCLKBIDA_02807 1.7e-308 ydiF S ABC transporter
HCLKBIDA_02808 2.3e-179 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCLKBIDA_02809 4.9e-87 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HCLKBIDA_02810 1.1e-130 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HCLKBIDA_02811 4.9e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HCLKBIDA_02812 2.9e-187 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HCLKBIDA_02814 1.2e-213 megL 2.5.1.48, 2.5.1.49, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
HCLKBIDA_02815 6.9e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCLKBIDA_02816 3.9e-63 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCLKBIDA_02817 1.3e-120 sapB S MgtC SapB transporter
HCLKBIDA_02819 7.2e-105 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCLKBIDA_02820 2e-177 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HCLKBIDA_02821 7.7e-109 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HCLKBIDA_02822 2.1e-199
HCLKBIDA_02823 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HCLKBIDA_02824 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
HCLKBIDA_02825 6.1e-82 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCLKBIDA_02826 1.3e-42 gatB_1 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HCLKBIDA_02827 1.9e-215 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
HCLKBIDA_02828 2.5e-197 gutB 1.1.1.1, 1.1.1.14 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HCLKBIDA_02829 3.3e-21
HCLKBIDA_02830 3.2e-211 gatD 1.1.1.14 C Alcohol dehydrogenase GroES-like domain
HCLKBIDA_02831 4.6e-299 expZ S ABC transporter
HCLKBIDA_02832 1.1e-71
HCLKBIDA_02833 2.7e-89 M Protein of unknown function (DUF1541)
HCLKBIDA_02834 4.4e-177 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HCLKBIDA_02835 1.4e-270 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HCLKBIDA_02836 5.5e-155 licT K antiterminator
HCLKBIDA_02837 1.9e-118
HCLKBIDA_02838 5e-105 K helix_turn_helix, Lux Regulon
HCLKBIDA_02839 6.5e-196 desK 2.7.13.3 T Histidine kinase
HCLKBIDA_02840 1.8e-221 G Transmembrane secretion effector
HCLKBIDA_02841 2.9e-284 T COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HCLKBIDA_02842 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HCLKBIDA_02843 2.1e-249 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HCLKBIDA_02844 6e-222 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HCLKBIDA_02845 3.4e-255 3.5.4.28, 3.5.4.31 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HCLKBIDA_02846 2.7e-236 S protein conserved in bacteria
HCLKBIDA_02847 4.7e-182 S COG1073 Hydrolases of the alpha beta superfamily
HCLKBIDA_02849 8.5e-93
HCLKBIDA_02850 1.2e-102 S Histidine kinase
HCLKBIDA_02851 1.5e-183 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCLKBIDA_02852 1.2e-57 FG HIT domain
HCLKBIDA_02853 3.6e-165 KLT Protein kinase domain
HCLKBIDA_02854 7.9e-80 S Stage II sporulation protein P (SpoIIP)
HCLKBIDA_02855 1.2e-141 K acetyltransferase
HCLKBIDA_02856 7.1e-104 K Bacterial regulatory proteins, tetR family
HCLKBIDA_02857 3.5e-217 codB_1 F cytosine purines uracil thiamine allantoin
HCLKBIDA_02858 1.4e-206 S Protein of unknown function (DUF917)
HCLKBIDA_02859 1.1e-289 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
HCLKBIDA_02860 4.8e-28
HCLKBIDA_02861 4.2e-118 ypgQ S phosphohydrolase
HCLKBIDA_02862 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HCLKBIDA_02863 5.5e-95 S Peptidase M50
HCLKBIDA_02864 2.9e-35 S membrane
HCLKBIDA_02866 7.7e-91 M FR47-like protein
HCLKBIDA_02867 8.6e-99 ydcN K Helix-turn-helix XRE-family like proteins
HCLKBIDA_02868 9.1e-119 azlC E AzlC protein
HCLKBIDA_02869 3.2e-50 S Branched-chain amino acid transport protein (AzlD)
HCLKBIDA_02870 3.8e-243 araN G ABC transporter substrate-binding protein
HCLKBIDA_02871 3.9e-162 lacF G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02872 4.9e-148 araQ P PFAM binding-protein-dependent transport systems inner membrane component
HCLKBIDA_02873 3.3e-30 mcbG S Pentapeptide repeats (9 copies)
HCLKBIDA_02874 1e-157 htpX O Belongs to the peptidase M48B family
HCLKBIDA_02875 7.7e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
HCLKBIDA_02877 1.2e-157 3.5.1.28 M COG3103 SH3 domain protein
HCLKBIDA_02878 2.9e-69 E lactoylglutathione lyase activity
HCLKBIDA_02879 0.0 ltaS 2.7.8.20 M Sulfatase
HCLKBIDA_02880 0.0 2.6.1.52 E Aminotransferase class-V
HCLKBIDA_02881 4.4e-92 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCLKBIDA_02882 2.6e-106 V Beta-lactamase
HCLKBIDA_02883 1.8e-156 yfhB 5.3.3.17 S PhzF family
HCLKBIDA_02884 9.8e-67 S Protein of unknown function, DUF393
HCLKBIDA_02885 1.6e-193 S Oxidoreductase family, NAD-binding Rossmann fold
HCLKBIDA_02886 7.2e-172 3.2.2.21 K Cupin domain
HCLKBIDA_02887 2e-140 G Xylose isomerase-like TIM barrel
HCLKBIDA_02888 1.2e-210 S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_02889 5.1e-256 G Bacterial extracellular solute-binding protein
HCLKBIDA_02890 2.8e-171 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02891 4.3e-155 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02892 4e-144 G Xylose isomerase-like TIM barrel
HCLKBIDA_02893 2.8e-101 3.2.2.21 K AraC-like ligand binding domain
HCLKBIDA_02894 4.2e-211 S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_02895 2.6e-227 S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_02896 9.9e-171 3.2.2.21 K AraC-like ligand binding domain
HCLKBIDA_02897 4.4e-216 3.2.1.180 GH88 O Glycosyl Hydrolase Family 88
HCLKBIDA_02898 1.6e-163 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02899 1.8e-148 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_02900 7.2e-258 G Bacterial extracellular solute-binding protein
HCLKBIDA_02902 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HCLKBIDA_02903 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCLKBIDA_02904 1e-240 3.5.1.47 S amidohydrolase
HCLKBIDA_02905 4.8e-132 S Protein of unknown function (DUF3100)
HCLKBIDA_02906 2.1e-77 S An automated process has identified a potential problem with this gene model
HCLKBIDA_02907 4.7e-65
HCLKBIDA_02908 5e-208 ytfP S HI0933-like protein
HCLKBIDA_02909 8.2e-229 yhaA1 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HCLKBIDA_02910 3.7e-72 yugU S Uncharacterised protein family UPF0047
HCLKBIDA_02911 4.2e-166 yvrE G SMP-30/Gluconolaconase/LRE-like region
HCLKBIDA_02912 1.5e-286 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCLKBIDA_02913 9.5e-198 ftsW D Belongs to the SEDS family
HCLKBIDA_02914 6.9e-212 rodA D Belongs to the SEDS family
HCLKBIDA_02915 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCLKBIDA_02916 1.5e-30 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HCLKBIDA_02917 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HCLKBIDA_02918 4.3e-152 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCLKBIDA_02919 4.3e-49 K helix_turn_helix, mercury resistance
HCLKBIDA_02920 4.3e-166 ydeE K AraC family transcriptional regulator
HCLKBIDA_02921 3.3e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HCLKBIDA_02922 1.5e-108 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HCLKBIDA_02923 2.9e-64 cidA S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HCLKBIDA_02924 7.3e-100 lrgB M effector of murein hydrolase
HCLKBIDA_02925 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HCLKBIDA_02926 5.2e-219 1.8.1.4 C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCLKBIDA_02927 1.4e-178 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HCLKBIDA_02928 9.9e-194 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HCLKBIDA_02929 1.9e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCLKBIDA_02930 5.7e-52 S PFAM Uncharacterised protein family UPF0150
HCLKBIDA_02931 3.5e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_02932 8.8e-164 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HCLKBIDA_02933 7.6e-154 ytmP 2.7.1.89 M Phosphotransferase
HCLKBIDA_02934 6.3e-14 S YtzH-like protein
HCLKBIDA_02935 5.8e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCLKBIDA_02936 5.7e-49 ytzB
HCLKBIDA_02937 1e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HCLKBIDA_02938 6.7e-90 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
HCLKBIDA_02939 1.9e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HCLKBIDA_02940 3.8e-118 S Phosphotransferase system, EIIC
HCLKBIDA_02941 1e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HCLKBIDA_02942 5.3e-147 ytpQ S Belongs to the UPF0354 family
HCLKBIDA_02943 7.7e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCLKBIDA_02944 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HCLKBIDA_02945 5.9e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HCLKBIDA_02946 4.3e-63 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCLKBIDA_02947 3.9e-16 XK27_07760 S COG4980 Gas vesicle protein
HCLKBIDA_02948 4.1e-198 aroA 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HCLKBIDA_02949 2.3e-185 ccpA K catabolite control protein A
HCLKBIDA_02950 1.2e-238 acuC BQ histone deacetylase
HCLKBIDA_02951 4e-116 acuB S Acetoin utilization protein AcuB
HCLKBIDA_02952 8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HCLKBIDA_02953 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HCLKBIDA_02954 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M COG0744 Membrane carboxypeptidase (penicillin-binding protein)
HCLKBIDA_02955 1.1e-234 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCLKBIDA_02956 1.3e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCLKBIDA_02957 2.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HCLKBIDA_02958 3.6e-114 yttP K Transcriptional regulator
HCLKBIDA_02959 1.6e-148 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HCLKBIDA_02960 1.3e-304 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCLKBIDA_02961 1.8e-204 iscS2 2.8.1.7 E Cysteine desulfurase
HCLKBIDA_02962 5.3e-223 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCLKBIDA_02963 8.1e-28 sspB S spore protein
HCLKBIDA_02964 3.5e-180 sppA OU signal peptide peptidase SppA
HCLKBIDA_02965 1.7e-99 yteJ S RDD family
HCLKBIDA_02966 5.4e-124 ytfI S Protein of unknown function (DUF2953)
HCLKBIDA_02967 8.4e-75 ytfJ S Sporulation protein YtfJ
HCLKBIDA_02968 2.4e-196 ywoG EGP Major facilitator Superfamily
HCLKBIDA_02969 2.3e-84 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCLKBIDA_02970 3.1e-181 ytxK 2.1.1.72 L DNA methylase
HCLKBIDA_02971 4.3e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCLKBIDA_02972 8.1e-171 yhaM S 3'-5' exoribonuclease yhaM
HCLKBIDA_02973 2.2e-12 S EcsC protein family
HCLKBIDA_02974 4.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCLKBIDA_02975 1.8e-259 argH 4.3.2.1 E argininosuccinate lyase
HCLKBIDA_02976 1.1e-267 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCLKBIDA_02977 0.0 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HCLKBIDA_02978 2e-307 yngK T Glycosyl hydrolase-like 10
HCLKBIDA_02979 4.2e-237 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCLKBIDA_02980 9.6e-245 agcS E Sodium alanine symporter
HCLKBIDA_02981 1.6e-94 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HCLKBIDA_02982 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HCLKBIDA_02983 1.7e-295 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCLKBIDA_02984 1.7e-232 pilS 2.7.13.3 T Histidine kinase
HCLKBIDA_02985 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HCLKBIDA_02986 1.5e-308 yfiB3 V ABC transporter
HCLKBIDA_02987 0.0 uvrD 3.6.4.12 L DNA helicase
HCLKBIDA_02988 1.6e-171 phnD P Phosphonate ABC transporter
HCLKBIDA_02989 7.5e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HCLKBIDA_02990 2.9e-137 phnE 3.6.1.63 P ABC transporter
HCLKBIDA_02991 2.3e-142 phnE 3.6.1.63 P ABC transporter
HCLKBIDA_02992 2.3e-142 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCLKBIDA_02993 2.9e-246 matE V MatE
HCLKBIDA_02994 1.2e-106 tetR K Bacterial regulatory proteins, tetR family
HCLKBIDA_02995 1.1e-163 3.4.11.5 I Alpha/beta hydrolase family
HCLKBIDA_02996 2.2e-160 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_02997 2.6e-183 dppB EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_02998 8.3e-304 E COG0747 ABC-type dipeptide transport system, periplasmic component
HCLKBIDA_02999 1.1e-189 appF E Belongs to the ABC transporter superfamily
HCLKBIDA_03000 1.2e-183 dppD P Belongs to the ABC transporter superfamily
HCLKBIDA_03001 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
HCLKBIDA_03002 4.1e-65 XK27_04860 S Domain of unknown function (DUF4440)
HCLKBIDA_03003 4.5e-102 ynaD J Acetyltransferase (GNAT) domain
HCLKBIDA_03004 5.1e-229 S Sulphur transport
HCLKBIDA_03005 1.8e-176 S transport system, periplasmic component
HCLKBIDA_03006 1.3e-171 S Belongs to the binding-protein-dependent transport system permease family
HCLKBIDA_03007 7.4e-141 S transport system, ATPase component
HCLKBIDA_03008 1.1e-194
HCLKBIDA_03009 6.6e-201 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HCLKBIDA_03010 3.8e-134 cysW P COG4208 ABC-type sulfate transport system, permease component
HCLKBIDA_03011 2e-133 cysT O COG0555 ABC-type sulfate transport system, permease component
HCLKBIDA_03012 3e-195 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
HCLKBIDA_03013 2.7e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCLKBIDA_03014 3.9e-182 T COG0642 Signal transduction histidine kinase
HCLKBIDA_03015 4.3e-86 T COG0642 Signal transduction histidine kinase
HCLKBIDA_03016 2.3e-262 dld 1.1.1.303, 1.1.1.4, 1.1.2.4, 1.1.3.15 C Glycolate oxidase subunit
HCLKBIDA_03017 4.6e-161 yocS S -transporter
HCLKBIDA_03018 4.3e-250 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCLKBIDA_03019 4.6e-160 nhaR K LysR substrate binding domain
HCLKBIDA_03020 2.3e-298 E COG0747 ABC-type dipeptide transport system, periplasmic component
HCLKBIDA_03021 6.5e-209 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HCLKBIDA_03022 3.9e-69 K Helix-turn-helix XRE-family like proteins
HCLKBIDA_03023 5.8e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
HCLKBIDA_03024 1e-153 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_03025 1.5e-172 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_03026 3.7e-273 G Bacterial extracellular solute-binding protein
HCLKBIDA_03027 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HCLKBIDA_03028 1.1e-172 yisR1 K AraC-like ligand binding domain
HCLKBIDA_03029 1e-125 mutF V ABC transporter, ATP-binding protein
HCLKBIDA_03030 1.7e-126 spaE S ABC-2 family transporter protein
HCLKBIDA_03031 2.1e-137 mutG S ABC-2 family transporter protein
HCLKBIDA_03032 8.1e-125 K Transcriptional regulatory protein, C terminal
HCLKBIDA_03033 4.3e-261 T His Kinase A (phosphoacceptor) domain
HCLKBIDA_03034 3.2e-74 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HCLKBIDA_03035 7.2e-74 lrpC K helix_turn_helix ASNC type
HCLKBIDA_03036 3e-105 argO S Lysine exporter protein LysE YggA
HCLKBIDA_03037 3.5e-274 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCLKBIDA_03038 8.9e-95 ykkA S Protein of unknown function (DUF664)
HCLKBIDA_03039 9.9e-76 yuxK S protein conserved in bacteria
HCLKBIDA_03040 3.3e-85 S Protein of unknown function (DUF1569)
HCLKBIDA_03041 2.4e-12
HCLKBIDA_03042 7.7e-64
HCLKBIDA_03043 2.5e-80 S SMI1-KNR4 cell-wall
HCLKBIDA_03044 1.4e-50
HCLKBIDA_03045 1.7e-21
HCLKBIDA_03046 1.4e-59
HCLKBIDA_03047 2.5e-104 S LXG domain of WXG superfamily
HCLKBIDA_03048 7.9e-39 S Family of unknown function (DUF5344)
HCLKBIDA_03050 1.9e-33 S response regulator aspartate phosphatase
HCLKBIDA_03051 8e-205 vraB 2.3.1.9 I Belongs to the thiolase family
HCLKBIDA_03052 7.4e-269 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HCLKBIDA_03053 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HCLKBIDA_03055 1.1e-195 3.6.3.20 P Belongs to the ABC transporter superfamily
HCLKBIDA_03056 8.3e-148 ugpE P PFAM binding-protein-dependent transport systems inner membrane component
HCLKBIDA_03057 1.3e-165 G ABC transporter (permease)
HCLKBIDA_03058 6.7e-150 G Xylose isomerase-like TIM barrel
HCLKBIDA_03059 2.1e-249 G Glycerol-3-phosphate ABC transporter substrate-binding protein
HCLKBIDA_03060 2.8e-75 ectC 4.2.1.108 S Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
HCLKBIDA_03061 2.5e-247 ectB 2.6.1.76 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCLKBIDA_03062 4.1e-89 ectA 2.3.1.178 K L-2,4-diaminobutyric acid acetyltransferase
HCLKBIDA_03063 1.3e-53
HCLKBIDA_03064 1.8e-270 EG Bacillus/Clostridium GerA spore germination protein
HCLKBIDA_03065 7.5e-269 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCLKBIDA_03066 8.4e-210 eutG C alcohol dehydrogenase
HCLKBIDA_03067 2.4e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
HCLKBIDA_03068 3e-235 EG COG2610 H gluconate symporter and related permeases
HCLKBIDA_03069 8.3e-221 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
HCLKBIDA_03070 0.0 KT Transcriptional regulator
HCLKBIDA_03071 1e-19
HCLKBIDA_03072 4.8e-54 fdx5 C 2Fe-2S iron-sulfur cluster binding domain
HCLKBIDA_03073 6.7e-98 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HCLKBIDA_03074 3.8e-10
HCLKBIDA_03075 6.9e-40 S Protein of unknown function (DUF2642)
HCLKBIDA_03076 5.9e-202 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HCLKBIDA_03077 7.2e-237 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCLKBIDA_03078 7.5e-158 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCLKBIDA_03079 9.8e-302 K Propionate catabolism activator
HCLKBIDA_03081 2.9e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HCLKBIDA_03082 1.1e-242 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
HCLKBIDA_03083 4.4e-183 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
HCLKBIDA_03084 2.5e-147 ybbH_2 K Transcriptional regulator
HCLKBIDA_03085 0.0 msbA2 3.6.3.44 V ABC transporter
HCLKBIDA_03086 2.5e-141 K helix_turn_helix, mercury resistance
HCLKBIDA_03087 2.1e-174 K helix_turn _helix lactose operon repressor
HCLKBIDA_03088 2.3e-187 G Bacterial extracellular solute-binding protein, family 7
HCLKBIDA_03089 9.9e-83 G Tripartite ATP-independent periplasmic transporters, DctQ component
HCLKBIDA_03090 7.5e-207 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
HCLKBIDA_03091 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HCLKBIDA_03093 1.4e-91 S Peptidase propeptide and YPEB domain
HCLKBIDA_03094 5e-287 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCLKBIDA_03095 4.3e-163 yueF S transporter activity
HCLKBIDA_03096 9.4e-86 ftnA 1.16.3.2 P Iron-storage protein
HCLKBIDA_03098 7.9e-99 adk 2.7.4.3 F topology modulation protein
HCLKBIDA_03099 7.7e-214 F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HCLKBIDA_03100 6.6e-167 I alpha/beta hydrolase fold
HCLKBIDA_03101 1.6e-117 ktrA P COG0569 K transport systems, NAD-binding component
HCLKBIDA_03102 0.0 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HCLKBIDA_03103 2.2e-87 2.3.1.128 J Acetyltransferase (GNAT) domain
HCLKBIDA_03104 4.1e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HCLKBIDA_03105 5.3e-72 S Protein of unknown function (DUF2512)
HCLKBIDA_03106 1.6e-66
HCLKBIDA_03107 5.8e-117 panZ K Acetyltransferase (GNAT) domain
HCLKBIDA_03108 5.7e-136 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HCLKBIDA_03109 2.6e-147 ydfC EG EamA-like transporter family
HCLKBIDA_03110 6.6e-122 Q SAM-dependent methyltransferase
HCLKBIDA_03111 3.1e-189 trpS 6.1.1.2 J Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HCLKBIDA_03112 3.2e-147 Q ubiE/COQ5 methyltransferase family
HCLKBIDA_03113 9.1e-92
HCLKBIDA_03114 3.5e-91 2.3.1.128 J Acetyltransferase (GNAT) domain
HCLKBIDA_03115 6.6e-206 P Oxidoreductase
HCLKBIDA_03116 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HCLKBIDA_03117 1.1e-62 cadC K transcriptional
HCLKBIDA_03118 3e-147 aadD H KNTase C-terminal domain
HCLKBIDA_03119 0.0 ydfJ S drug exporters of the RND superfamily
HCLKBIDA_03120 2.7e-09 K transcriptional regulator
HCLKBIDA_03127 4.7e-87 ydcK S Belongs to the SprT family
HCLKBIDA_03128 3.9e-08
HCLKBIDA_03129 0.0 yhgF K COG2183 Transcriptional accessory protein
HCLKBIDA_03130 3.1e-118 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HCLKBIDA_03131 4.3e-141 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HCLKBIDA_03132 3.3e-83 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HCLKBIDA_03133 3.7e-54 rsbV T Belongs to the anti-sigma-factor antagonist family
HCLKBIDA_03134 2.3e-187 rsbU 3.1.3.3 KT phosphatase
HCLKBIDA_03135 7.2e-74 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HCLKBIDA_03136 4.5e-53 rsbS T antagonist
HCLKBIDA_03137 3e-145 rsbR T Positive regulator of sigma-B
HCLKBIDA_03138 4.4e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HCLKBIDA_03139 8e-25 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HCLKBIDA_03140 2.8e-232 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCLKBIDA_03141 1.8e-187 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HCLKBIDA_03142 2e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCLKBIDA_03143 1.6e-132 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HCLKBIDA_03144 1.2e-101 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCLKBIDA_03145 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HCLKBIDA_03146 1.1e-141 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HCLKBIDA_03147 1.1e-47
HCLKBIDA_03148 6.4e-111 S Integral membrane protein
HCLKBIDA_03149 1.7e-218 S Winged helix DNA-binding domain
HCLKBIDA_03150 7.7e-140 G Xylose isomerase-like TIM barrel
HCLKBIDA_03151 3.7e-193 S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_03152 3.5e-193 G Xylose isomerase
HCLKBIDA_03153 2.8e-162 S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
HCLKBIDA_03154 5.4e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HCLKBIDA_03155 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCLKBIDA_03156 1.7e-85 mrpE P Na+/H+ ion antiporter subunit
HCLKBIDA_03157 4.9e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCLKBIDA_03158 4.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HCLKBIDA_03159 1.1e-66 mnhB2 P antiporter activity
HCLKBIDA_03160 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HCLKBIDA_03161 1.7e-130 T PhoQ Sensor
HCLKBIDA_03162 7.1e-112 S Nitroreductase family
HCLKBIDA_03163 3.1e-59 hxlR K transcriptional
HCLKBIDA_03164 4e-184 ykfD E Belongs to the ABC transporter superfamily
HCLKBIDA_03165 1.5e-174 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HCLKBIDA_03166 3.1e-178 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HCLKBIDA_03167 0.0 dppE E ABC transporter substrate-binding protein
HCLKBIDA_03168 1.8e-184 dppD P Belongs to the ABC transporter superfamily
HCLKBIDA_03169 3.3e-172 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_03170 1e-162 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_03171 1.8e-150 dppA E D-aminopeptidase
HCLKBIDA_03172 2e-233 2.7.13.3 T Histidine kinase-like ATPases
HCLKBIDA_03173 9.5e-158 ycbB1 T YcbB domain
HCLKBIDA_03174 1.7e-106 glnP P ABC transporter
HCLKBIDA_03175 7.1e-110 gluC P ABC transporter
HCLKBIDA_03176 1e-148 glnH ET Belongs to the bacterial solute-binding protein 3 family
HCLKBIDA_03177 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCLKBIDA_03178 8.1e-160 rarD S -transporter
HCLKBIDA_03179 2.9e-201 pgl 3.1.1.31 G 6-phosphogluconolactonase
HCLKBIDA_03180 1.2e-200 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HCLKBIDA_03181 1.2e-233 QT Transcriptional regulator
HCLKBIDA_03182 3.9e-161 sseA 2.8.1.1, 2.8.1.2 P sulfurtransferase
HCLKBIDA_03183 1.2e-250 yeeF E Amino acid permease
HCLKBIDA_03184 1.4e-112 cwlK M Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin
HCLKBIDA_03185 4.1e-234 K Helix-turn-helix XRE-family like proteins
HCLKBIDA_03186 7e-201 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HCLKBIDA_03188 5.6e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCLKBIDA_03189 1.7e-173 yfhM S Alpha beta hydrolase
HCLKBIDA_03190 7.5e-141 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HCLKBIDA_03191 1.8e-176 S Phosphotransferase system, EIIC
HCLKBIDA_03192 6.3e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HCLKBIDA_03193 3.7e-96 tag 3.2.2.20 L Methyladenine glycosylase
HCLKBIDA_03194 2.8e-128
HCLKBIDA_03195 7e-95 3.4.21.89 U Signal peptidase
HCLKBIDA_03196 0.0 vpr O Belongs to the peptidase S8 family
HCLKBIDA_03197 1.5e-72 ctsR K Belongs to the CtsR family
HCLKBIDA_03198 8.9e-95 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HCLKBIDA_03199 1.6e-194 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HCLKBIDA_03200 0.0 clpC O Belongs to the ClpA ClpB family
HCLKBIDA_03201 2.1e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCLKBIDA_03202 2.7e-194 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HCLKBIDA_03203 1.4e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HCLKBIDA_03204 1.5e-118 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HCLKBIDA_03205 2.3e-84 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HCLKBIDA_03206 1.8e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCLKBIDA_03207 2.5e-121 cysE 2.3.1.30 E Serine acetyltransferase
HCLKBIDA_03208 3.9e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCLKBIDA_03209 5.1e-69 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCLKBIDA_03210 1.1e-144 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCLKBIDA_03211 3e-87 yacP S RNA-binding protein containing a PIN domain
HCLKBIDA_03212 5.6e-118 sigH K Belongs to the sigma-70 factor family
HCLKBIDA_03213 6.1e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCLKBIDA_03214 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HCLKBIDA_03215 6.3e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCLKBIDA_03216 9.4e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCLKBIDA_03217 3.5e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCLKBIDA_03218 3.2e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCLKBIDA_03219 6.4e-122 rsmC 2.1.1.172 J Methyltransferase
HCLKBIDA_03220 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCLKBIDA_03221 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCLKBIDA_03222 1e-35 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
HCLKBIDA_03223 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCLKBIDA_03224 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCLKBIDA_03225 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCLKBIDA_03226 6.6e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCLKBIDA_03227 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HCLKBIDA_03228 1.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCLKBIDA_03229 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
HCLKBIDA_03230 1.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCLKBIDA_03231 1.7e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCLKBIDA_03232 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCLKBIDA_03233 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCLKBIDA_03234 8.7e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCLKBIDA_03235 4.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCLKBIDA_03236 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
HCLKBIDA_03237 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCLKBIDA_03238 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCLKBIDA_03239 6.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCLKBIDA_03240 2.3e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCLKBIDA_03241 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCLKBIDA_03242 1.3e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCLKBIDA_03243 1.3e-60 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCLKBIDA_03244 4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCLKBIDA_03245 2.7e-25 rpmD J Ribosomal protein L30
HCLKBIDA_03246 3.3e-74 rplO J binds to the 23S rRNA
HCLKBIDA_03247 2.2e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCLKBIDA_03248 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCLKBIDA_03249 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HCLKBIDA_03250 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCLKBIDA_03251 1.4e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HCLKBIDA_03252 1.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCLKBIDA_03253 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCLKBIDA_03254 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCLKBIDA_03255 9.4e-59 rplQ J Ribosomal protein L17
HCLKBIDA_03256 8.4e-162 ecfA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCLKBIDA_03257 6.9e-153 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCLKBIDA_03258 1.2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCLKBIDA_03259 1.1e-147 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCLKBIDA_03260 4.4e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCLKBIDA_03261 1.7e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HCLKBIDA_03262 2.8e-83 S Protein of unknown function (DUF2975)
HCLKBIDA_03263 1.9e-30 yozG K Transcriptional regulator
HCLKBIDA_03265 5.6e-116 S Rubrerythrin
HCLKBIDA_03266 6.6e-14
HCLKBIDA_03269 8.9e-80 ybaK S Protein of unknown function (DUF2521)
HCLKBIDA_03270 4.4e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HCLKBIDA_03271 1.1e-150 glcT K antiterminator
HCLKBIDA_03272 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCLKBIDA_03273 3.2e-192 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HCLKBIDA_03274 1.5e-58 gerD S Spore gernimation protein
HCLKBIDA_03275 2.2e-100 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HCLKBIDA_03276 3.4e-143 pdaB 3.5.1.104 G Polysaccharide deacetylase
HCLKBIDA_03277 2.7e-33
HCLKBIDA_03278 2.5e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HCLKBIDA_03279 3e-223 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCLKBIDA_03280 6.8e-136 lacR K DeoR C terminal sensor domain
HCLKBIDA_03281 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HCLKBIDA_03282 5.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCLKBIDA_03283 1.1e-242 G ABC transporter substrate-binding protein
HCLKBIDA_03284 1.1e-161 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_03285 1.4e-156 P PFAM binding-protein-dependent transport systems inner membrane component
HCLKBIDA_03286 3.3e-61 Z012_01525 FJ tRNA wobble adenosine to inosine editing
HCLKBIDA_03287 5.4e-13 S Inner spore coat protein D
HCLKBIDA_03288 0.0 M1-554 G Endonuclease Exonuclease Phosphatase
HCLKBIDA_03289 0.0 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HCLKBIDA_03290 3.6e-199 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCLKBIDA_03291 3e-134 potC3 P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_03292 2.1e-138 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
HCLKBIDA_03293 4.1e-175 iunH3 3.2.2.1 F nucleoside hydrolase
HCLKBIDA_03294 7.3e-197 potD2 E COG0687 Spermidine putrescine-binding periplasmic protein
HCLKBIDA_03295 2.4e-56
HCLKBIDA_03296 1.4e-50
HCLKBIDA_03298 1.3e-165 T Belongs to the universal stress protein A family
HCLKBIDA_03299 2e-141 rpl K Helix-turn-helix domain, rpiR family
HCLKBIDA_03300 7.3e-172 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
HCLKBIDA_03301 1.8e-230 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HCLKBIDA_03302 4.3e-62 fruD 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCLKBIDA_03303 3.6e-157 kbaY 4.1.2.13, 4.1.2.40 G in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
HCLKBIDA_03304 5.8e-72
HCLKBIDA_03305 4.7e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HCLKBIDA_03309 2.4e-161 K LysR substrate binding domain
HCLKBIDA_03310 1.7e-104 ywqN S NAD(P)H-dependent
HCLKBIDA_03311 1.8e-72 fabH 2.3.1.180 I Chalcone and stilbene synthases, N-terminal domain
HCLKBIDA_03312 4.9e-117 K Transcriptional regulator
HCLKBIDA_03313 1.5e-198 V COG0842 ABC-type multidrug transport system, permease component
HCLKBIDA_03314 1.7e-142 V COG1131 ABC-type multidrug transport system, ATPase component
HCLKBIDA_03315 4e-80 M PFAM secretion protein HlyD family protein
HCLKBIDA_03316 4.2e-214 MA20_04465 4.2.3.1 E Pyridoxal-phosphate dependent enzyme
HCLKBIDA_03317 4.6e-143 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HCLKBIDA_03318 1.1e-242 KT transcriptional regulatory protein
HCLKBIDA_03319 4.2e-275 abgB 3.5.1.47 S amidohydrolase
HCLKBIDA_03320 1.3e-279 abgT H AbgT putative transporter family
HCLKBIDA_03321 9.4e-247 3.5.1.47 S Peptidase dimerisation domain
HCLKBIDA_03322 2.5e-23 C 4Fe-4S binding domain
HCLKBIDA_03323 5.7e-39 S Protein of unknown function (DUF1450)
HCLKBIDA_03324 5.5e-115 sodA 1.15.1.1 P Iron/manganese superoxide dismutases, C-terminal domain
HCLKBIDA_03325 1.2e-117 sufR K Transcriptional regulator
HCLKBIDA_03326 1.4e-257 S Polysaccharide biosynthesis protein
HCLKBIDA_03327 5.9e-154 exoM S Glycosyl transferase family 2
HCLKBIDA_03328 9.3e-203 M Glycosyl transferases group 1
HCLKBIDA_03329 1.2e-55
HCLKBIDA_03330 8.4e-249 M -O-antigen
HCLKBIDA_03331 3e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HCLKBIDA_03332 7.8e-70
HCLKBIDA_03333 3.1e-141 tuaG GT2 M Glycosyltransferase like family 2
HCLKBIDA_03334 2.4e-174 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HCLKBIDA_03335 1e-176 S Oxidoreductase family, NAD-binding Rossmann fold
HCLKBIDA_03337 4.4e-22
HCLKBIDA_03340 1.1e-247 UW nuclease activity
HCLKBIDA_03353 5.2e-08
HCLKBIDA_03354 7.8e-20
HCLKBIDA_03355 8.6e-93 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCLKBIDA_03356 4.9e-116 adaA 3.2.2.21 K Transcriptional regulator
HCLKBIDA_03357 2.5e-177 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HCLKBIDA_03358 2.9e-212 S Oxidoreductase family, NAD-binding Rossmann fold
HCLKBIDA_03359 1.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCLKBIDA_03360 1.3e-153 yidA S hydrolases of the HAD superfamily
HCLKBIDA_03361 9.9e-91 S DinB family
HCLKBIDA_03362 1.4e-167 K WYL domain
HCLKBIDA_03363 3.3e-103 S Bacteriocin-protection, YdeI or OmpD-Associated
HCLKBIDA_03364 6.9e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCLKBIDA_03365 1.3e-190 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCLKBIDA_03367 5.6e-118 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCLKBIDA_03368 3.6e-210 yhcY 2.7.13.3 T Histidine kinase
HCLKBIDA_03369 1.9e-39
HCLKBIDA_03370 1.1e-11 KLT serine threonine protein kinase
HCLKBIDA_03371 2.4e-118 KLT serine threonine protein kinase
HCLKBIDA_03372 5.7e-86 K Transcriptional regulator
HCLKBIDA_03373 2.3e-141 3.1.26.11 S Metallo-beta-lactamase superfamily
HCLKBIDA_03374 4.1e-110 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HCLKBIDA_03375 9.5e-07
HCLKBIDA_03376 1.5e-141
HCLKBIDA_03377 2.1e-123 yhcG V ABC transporter, ATP-binding protein
HCLKBIDA_03378 8.6e-63 K helix_turn_helix gluconate operon transcriptional repressor
HCLKBIDA_03380 5.7e-136
HCLKBIDA_03381 1.3e-159 S NYN domain
HCLKBIDA_03382 5.5e-53 K sequence-specific DNA binding
HCLKBIDA_03383 1.2e-299 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HCLKBIDA_03384 3.3e-258 G Bacterial extracellular solute-binding protein
HCLKBIDA_03385 3.3e-161 araP G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_03386 1.3e-157 araQ P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_03387 2.6e-205 msmX E ABC transporter
HCLKBIDA_03388 6.1e-115
HCLKBIDA_03390 2e-183 scrR K transcriptional
HCLKBIDA_03392 1.3e-176 lplB7 G COG4209 ABC-type polysaccharide transport system, permease component
HCLKBIDA_03393 1.7e-162 lplC7 G COG0395 ABC-type sugar transport system, permease component
HCLKBIDA_03394 0.0 lplA5 G Bacterial extracellular solute-binding protein
HCLKBIDA_03395 0.0 sacC 3.2.1.26, 3.2.1.80 GH32 G invertase
HCLKBIDA_03396 2.4e-302 cscA 3.2.1.26, 3.2.1.80 GH32 G invertase
HCLKBIDA_03397 1.9e-133 IQ Enoyl-(Acyl carrier protein) reductase
HCLKBIDA_03398 1.8e-216 yaaH M Glycoside Hydrolase Family
HCLKBIDA_03399 1.2e-26
HCLKBIDA_03400 2.2e-99 pncA Q COG1335 Amidases related to nicotinamidase
HCLKBIDA_03401 3e-113 ymaB S MutT family
HCLKBIDA_03402 1.2e-191 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCLKBIDA_03403 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCLKBIDA_03404 4.2e-65 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HCLKBIDA_03405 3.3e-138 E lipolytic protein G-D-S-L family
HCLKBIDA_03406 3.2e-197 exoA M Glycosyltransferase like family 2
HCLKBIDA_03407 1.8e-251 wcaJ M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HCLKBIDA_03408 4.5e-235 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HCLKBIDA_03409 6.1e-137 2.7.8.34 I CDP-alcohol phosphatidyltransferase
HCLKBIDA_03410 9e-71 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HCLKBIDA_03411 0.0 tagF 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCLKBIDA_03412 2.9e-290 M Glycosyltransferase like family 2
HCLKBIDA_03413 9.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HCLKBIDA_03414 1.4e-187 ywtF K Transcriptional regulator
HCLKBIDA_03415 1.4e-80 asnC K helix_turn_helix ASNC type
HCLKBIDA_03416 2e-194 oppD P Belongs to the ABC transporter superfamily
HCLKBIDA_03417 3.7e-147 oppF P Belongs to the ABC transporter superfamily
HCLKBIDA_03418 1.5e-175 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_03419 4e-151 oppC EP binding-protein-dependent transport systems inner membrane component
HCLKBIDA_03420 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
HCLKBIDA_03421 6.2e-108 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HCLKBIDA_03422 6.6e-116 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HCLKBIDA_03423 4.1e-201 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HCLKBIDA_03424 1.5e-22 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HCLKBIDA_03425 7.6e-152 degV S protein conserved in bacteria
HCLKBIDA_03426 1.6e-188 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HCLKBIDA_03427 6.8e-130 comFC S Phosphoribosyl transferase domain
HCLKBIDA_03428 4.5e-76 yvyF S flagellar protein
HCLKBIDA_03429 1.2e-39 N Anti-sigma-28 factor, FlgM
HCLKBIDA_03431 1.2e-296 flgK N flagellar hook-associated protein
HCLKBIDA_03432 3.2e-192 flgL N Belongs to the bacterial flagellin family
HCLKBIDA_03433 7.1e-77 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HCLKBIDA_03434 1.2e-33 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HCLKBIDA_03435 1.2e-49 flaG N flagellar protein FlaG
HCLKBIDA_03436 0.0 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HCLKBIDA_03437 6.7e-66 fliS N flagellar protein FliS
HCLKBIDA_03439 2.6e-152
HCLKBIDA_03440 2.9e-30 cspB K cold-shock protein
HCLKBIDA_03441 7.1e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCLKBIDA_03442 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCLKBIDA_03443 8.8e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCLKBIDA_03444 1.1e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HCLKBIDA_03445 1.4e-124 ftsE D cell division ATP-binding protein FtsE
HCLKBIDA_03446 2.7e-152 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HCLKBIDA_03447 6.9e-102 D peptidase
HCLKBIDA_03448 5.3e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HCLKBIDA_03449 1.7e-205 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCLKBIDA_03450 2.2e-171 yoaV3 EG EamA-like transporter family
HCLKBIDA_03451 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCLKBIDA_03452 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCLKBIDA_03453 1.9e-152 yvlB S Putative adhesin
HCLKBIDA_03455 2.4e-48 yvlD S Membrane
HCLKBIDA_03456 1.6e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCLKBIDA_03457 2.1e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCLKBIDA_03458 4.5e-161 yvoD P COG0370 Fe2 transport system protein B
HCLKBIDA_03459 4.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HCLKBIDA_03460 4.7e-74 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HCLKBIDA_03461 7e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HCLKBIDA_03462 2.1e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HCLKBIDA_03463 2.3e-229 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCLKBIDA_03464 4.2e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HCLKBIDA_03465 4.5e-117 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCLKBIDA_03466 9.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HCLKBIDA_03467 1.6e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCLKBIDA_03468 3.3e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HCLKBIDA_03469 2.5e-146 yobR 2.3.1.1 K FR47-like protein
HCLKBIDA_03470 1.1e-239 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HCLKBIDA_03472 3.3e-71 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HCLKBIDA_03473 1.6e-61 divIC D Septum formation initiator
HCLKBIDA_03474 1.7e-67 yabQ S spore cortex biosynthesis protein
HCLKBIDA_03475 6.7e-53 yabP S Sporulation protein YabP
HCLKBIDA_03476 2e-103 MA20_20865 3.6.1.27 S SNARE associated Golgi protein
HCLKBIDA_03477 1.9e-200 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HCLKBIDA_03478 1e-87 2.3.1.128 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCLKBIDA_03479 7.8e-177 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCLKBIDA_03480 4.3e-118 S hydrolase
HCLKBIDA_03481 9e-24 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HCLKBIDA_03482 8.5e-276 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HCLKBIDA_03483 2.9e-274 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCLKBIDA_03484 5.2e-89 S Yip1 domain
HCLKBIDA_03485 7.2e-200 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCLKBIDA_03486 1.3e-90 S Yip1 domain
HCLKBIDA_03487 1.2e-94 spoVT K stage V sporulation protein
HCLKBIDA_03488 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCLKBIDA_03489 6.8e-39 yabK S Peptide ABC transporter permease
HCLKBIDA_03490 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCLKBIDA_03491 2.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HCLKBIDA_03492 5.3e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCLKBIDA_03493 6.5e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCLKBIDA_03494 1.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HCLKBIDA_03495 2.1e-61 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HCLKBIDA_03496 1.9e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HCLKBIDA_03497 4.8e-165 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCLKBIDA_03498 3.3e-25 sspF S DNA topological change
HCLKBIDA_03499 1.2e-39 veg S protein conserved in bacteria
HCLKBIDA_03500 1.3e-162 yabG S peptidase
HCLKBIDA_03501 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCLKBIDA_03502 1.2e-115 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCLKBIDA_03503 7.5e-215 rpfB GH23 T protein conserved in bacteria
HCLKBIDA_03504 4e-147 tatD L hydrolase, TatD
HCLKBIDA_03505 4.4e-268 S Protein of unknown function (DUF3298)
HCLKBIDA_03506 5.9e-120 T protein histidine kinase activity
HCLKBIDA_03507 7.2e-284 S ABC transporter
HCLKBIDA_03509 3.6e-185 pelB 4.2.2.2 G Amb_all
HCLKBIDA_03510 3.9e-81 K DNA-binding transcription factor activity
HCLKBIDA_03511 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCLKBIDA_03512 0.0 S Domain of unknown function DUF87
HCLKBIDA_03513 6.5e-176 S NurA
HCLKBIDA_03514 1.1e-43 abrB K COG2002 Regulators of stationary sporulation gene expression
HCLKBIDA_03515 1.2e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCLKBIDA_03516 3.7e-44 yazA L endonuclease containing a URI domain
HCLKBIDA_03517 8e-39 yabA L Involved in initiation control of chromosome replication
HCLKBIDA_03518 4.4e-144 yaaT S stage 0 sporulation protein
HCLKBIDA_03519 9.7e-183 holB 2.7.7.7 L DNA polymerase III
HCLKBIDA_03520 1.1e-53 yaaQ S protein conserved in bacteria
HCLKBIDA_03521 1.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCLKBIDA_03522 5.8e-277 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HCLKBIDA_03524 2.1e-185 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCLKBIDA_03525 2.1e-277 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HCLKBIDA_03526 1.2e-199 adhA 1.1.1.1 C alcohol dehydrogenase
HCLKBIDA_03527 6e-274 T Sigma-54 interaction domain
HCLKBIDA_03528 5.8e-280 cckA 2.7.13.3 T GAF domain
HCLKBIDA_03529 1.7e-12
HCLKBIDA_03530 1.4e-209 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
HCLKBIDA_03531 5.5e-172 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HCLKBIDA_03532 6.8e-276 mdr EGP Major facilitator Superfamily
HCLKBIDA_03533 0.0 rocB E arginine degradation protein
HCLKBIDA_03534 9.4e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HCLKBIDA_03535 2.5e-49
HCLKBIDA_03536 7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_03537 1.5e-194 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HCLKBIDA_03538 3.9e-142 yvcR V ABC transporter, ATP-binding protein
HCLKBIDA_03539 0.0 V ABC transporter (permease)
HCLKBIDA_03541 0.0 copA 3.6.3.54 P P-type ATPase
HCLKBIDA_03542 2.5e-161 S CAAX amino terminal protease family protein
HCLKBIDA_03543 5.6e-172 K Putative sugar-binding domain
HCLKBIDA_03544 1.3e-60 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HCLKBIDA_03545 4e-184 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
HCLKBIDA_03546 5.6e-89 srlA G PTS system enzyme II sorbitol-specific factor
HCLKBIDA_03547 9.8e-68 K Glucitol operon activator protein (GutM)
HCLKBIDA_03548 9.6e-236 thrA E SAF
HCLKBIDA_03549 6.6e-35 ptsH G PTS HPr component phosphorylation site
HCLKBIDA_03550 2.9e-120
HCLKBIDA_03551 5.9e-92 S VanZ like family
HCLKBIDA_03552 1.3e-78 yybA 2.3.1.57 K transcriptional
HCLKBIDA_03553 5.5e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCLKBIDA_03554 2.1e-174 ssuA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HCLKBIDA_03555 1.5e-104 ssuC P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_03556 2.3e-156 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HCLKBIDA_03557 3.4e-255 glcF C Glycolate oxidase
HCLKBIDA_03558 3.1e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
HCLKBIDA_03559 1.3e-207 ysfB KT regulator
HCLKBIDA_03560 1.4e-234 yxiO S COG2270 Permeases of the major facilitator superfamily
HCLKBIDA_03561 1.1e-142 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCLKBIDA_03563 1.7e-204 S Tetratricopeptide repeat
HCLKBIDA_03564 1.4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
HCLKBIDA_03566 2.1e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HCLKBIDA_03567 1.7e-90
HCLKBIDA_03568 6.5e-128 S KR domain
HCLKBIDA_03569 4.8e-148
HCLKBIDA_03570 1.2e-213 ysh1 J Metallo-beta-lactamase superfamily
HCLKBIDA_03571 1.3e-293 ftpA P Binding-protein-dependent transport system inner membrane component
HCLKBIDA_03572 7.7e-191 ftpB P Bacterial extracellular solute-binding protein
HCLKBIDA_03573 1.5e-183 phnT 3.6.3.30 P ABC transporter
HCLKBIDA_03574 6.1e-160 rbcR1 K Transcriptional regulator
HCLKBIDA_03575 4.1e-124 S Haloacid dehalogenase-like hydrolase
HCLKBIDA_03576 6.3e-58 S Family of unknown function (DUF5367)
HCLKBIDA_03577 4.7e-100 K Bacterial regulatory proteins, tetR family
HCLKBIDA_03579 3.9e-162 EG EamA-like transporter family
HCLKBIDA_03580 1.5e-253 ywoF P Right handed beta helix region
HCLKBIDA_03581 1.5e-97 mutT 3.6.1.13, 3.6.1.55 L nUDIX hydrolase
HCLKBIDA_03582 1.7e-257 4.3.2.2, 5.5.1.2 F Adenylosuccinate lyase C-terminus
HCLKBIDA_03583 1.1e-286 malX 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HCLKBIDA_03584 1.7e-139 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HCLKBIDA_03585 1.2e-61
HCLKBIDA_03586 1.7e-96 S DinB superfamily
HCLKBIDA_03587 3.7e-298 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HCLKBIDA_03588 7.5e-58
HCLKBIDA_03589 6.1e-96
HCLKBIDA_03590 1.3e-123
HCLKBIDA_03591 7.6e-52 K Transcriptional regulator
HCLKBIDA_03592 9e-25 UW nuclease activity
HCLKBIDA_03593 2.7e-23
HCLKBIDA_03595 7.7e-234 S membrane
HCLKBIDA_03596 2.6e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HCLKBIDA_03598 3.5e-70 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HCLKBIDA_03599 2e-114 mucD 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCLKBIDA_03600 2e-61 yojF S Protein of unknown function (DUF1806)
HCLKBIDA_03601 8.2e-125 bshB2 S deacetylase
HCLKBIDA_03602 1.5e-166 polA 2.7.7.7 L Helix-hairpin-helix class 2 (Pol1 family) motifs
HCLKBIDA_03603 5.8e-105 speG J Acetyltransferase (GNAT) domain
HCLKBIDA_03604 1.6e-90 yocC
HCLKBIDA_03605 1.3e-57 ytxJ O Protein of unknown function (DUF2847)
HCLKBIDA_03606 0.0 recQ 3.6.4.12 L DNA helicase
HCLKBIDA_03607 9e-158 S reductase
HCLKBIDA_03608 4e-303 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HCLKBIDA_03609 5.4e-32 yozC
HCLKBIDA_03610 5.2e-189 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HCLKBIDA_03611 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HCLKBIDA_03613 5.6e-208 2.1.1.163, 2.1.1.201 Q O-methyltransferase
HCLKBIDA_03614 6.3e-119 M lytic transglycosylase activity
HCLKBIDA_03615 1.8e-75 osmC O redox protein, regulator of disulfide bond formation
HCLKBIDA_03616 0.0 topB1 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCLKBIDA_03618 2.3e-173 V COG1131 ABC-type multidrug transport system, ATPase component
HCLKBIDA_03619 1.6e-126 V ABC-2 type transporter
HCLKBIDA_03620 1.6e-120 S ABC-2 type transporter
HCLKBIDA_03621 3.9e-193 T Histidine kinase
HCLKBIDA_03622 6e-106 KT LuxR family transcriptional regulator
HCLKBIDA_03623 9.5e-12 KT LuxR family transcriptional regulator
HCLKBIDA_03624 1.7e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HCLKBIDA_03625 3e-125 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HCLKBIDA_03626 1.2e-76 queD 4.1.2.50, 4.2.3.12 H synthase
HCLKBIDA_03627 3.5e-128 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HCLKBIDA_03628 2.1e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HCLKBIDA_03629 1.4e-251 agcS E Sodium alanine symporter
HCLKBIDA_03630 7.2e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HCLKBIDA_03631 2.5e-43 ywcE S Required for proper spore morphogenesis. Important for spore germination
HCLKBIDA_03633 5.1e-72 K helix_turn_helix multiple antibiotic resistance protein
HCLKBIDA_03634 4.8e-16
HCLKBIDA_03635 4.5e-16
HCLKBIDA_03638 7.2e-256 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HCLKBIDA_03639 7.7e-140 celG 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
HCLKBIDA_03640 2.2e-254 pagL 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HCLKBIDA_03641 4.2e-127 mngR K UTRA
HCLKBIDA_03642 1.8e-113 S CAAX protease self-immunity
HCLKBIDA_03643 2.3e-188 3.5.1.28 M COG3103 SH3 domain protein
HCLKBIDA_03644 3.2e-166 ydhU P Catalase
HCLKBIDA_03645 5.2e-150 S Nucleotidyltransferase domain
HCLKBIDA_03646 7.9e-27
HCLKBIDA_03647 5.7e-129 bshB1 S proteins, LmbE homologs
HCLKBIDA_03648 8.7e-201 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HCLKBIDA_03649 1.8e-209 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCLKBIDA_03650 3.5e-177 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCLKBIDA_03651 2.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HCLKBIDA_03652 3.5e-171 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HCLKBIDA_03653 2.7e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HCLKBIDA_03654 6.2e-179 S Tetratricopeptide repeat
HCLKBIDA_03655 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HCLKBIDA_03656 1.9e-247 mtaD 3.5.4.28, 3.5.4.31 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
HCLKBIDA_03657 7.8e-14
HCLKBIDA_03658 4.2e-22 ypmA S Protein of unknown function (DUF4264)
HCLKBIDA_03659 1.5e-83 ypmB S protein conserved in bacteria
HCLKBIDA_03660 1.2e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HCLKBIDA_03661 1.3e-128 dnaD L DNA replication protein DnaD
HCLKBIDA_03662 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCLKBIDA_03663 0.0 ypbR S Dynamin family
HCLKBIDA_03664 0.0 pbp1A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCLKBIDA_03665 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCLKBIDA_03666 3.5e-171 yppC S Protein of unknown function (DUF2515)
HCLKBIDA_03668 9.2e-92 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HCLKBIDA_03669 2.7e-61 yppE S Bacterial domain of unknown function (DUF1798)
HCLKBIDA_03670 6e-15
HCLKBIDA_03671 5.6e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HCLKBIDA_03672 4.1e-98 pfpI 3.5.1.124 S DJ-1/PfpI family
HCLKBIDA_03673 4.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCLKBIDA_03674 7.4e-55 yusE CO cell redox homeostasis
HCLKBIDA_03675 4.2e-77 yphP S Belongs to the UPF0403 family
HCLKBIDA_03676 1.1e-74 CO Thioredoxin-like
HCLKBIDA_03677 2.4e-138 T Calcineurin-like phosphoesterase superfamily domain
HCLKBIDA_03678 8.8e-148 ypgR C COG0694 Thioredoxin-like proteins and domains
HCLKBIDA_03679 1.9e-30
HCLKBIDA_03680 2.1e-85 ydbS S Bacterial PH domain
HCLKBIDA_03681 9.5e-259 ydbT S Membrane
HCLKBIDA_03682 1.2e-185 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_03683 2.2e-07
HCLKBIDA_03684 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCLKBIDA_03685 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCLKBIDA_03686 1.1e-09 yaaB S Domain of unknown function (DUF370)
HCLKBIDA_03687 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCLKBIDA_03688 9.1e-33 yaaA S S4 domain
HCLKBIDA_03689 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCLKBIDA_03690 4.5e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCLKBIDA_03691 1.9e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HCLKBIDA_03692 6e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCLKBIDA_03693 3.9e-127 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCLKBIDA_03694 1.3e-111 jag S single-stranded nucleic acid binding R3H
HCLKBIDA_03696 3.2e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCLKBIDA_03697 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCLKBIDA_03698 5.8e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HCLKBIDA_03699 1.6e-149 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HCLKBIDA_03700 2e-135 soj D COG1192 ATPases involved in chromosome partitioning
HCLKBIDA_03701 9.2e-153 spo0J K Belongs to the ParB family
HCLKBIDA_03702 1.6e-216 sufS 2.8.1.7, 4.4.1.16 E Aminotransferase class-V
HCLKBIDA_03703 1.1e-115 yyaC S Sporulation protein YyaC
HCLKBIDA_03704 7.3e-181 yyaD S Membrane
HCLKBIDA_03705 1.8e-27 yyzM S protein conserved in bacteria
HCLKBIDA_03706 2.7e-194 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCLKBIDA_03707 6.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
HCLKBIDA_03708 1.6e-58 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCLKBIDA_03709 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCLKBIDA_03710 1.7e-149 yybS S membrane
HCLKBIDA_03711 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HCLKBIDA_03712 7.7e-55 rplI J binds to the 23S rRNA
HCLKBIDA_03713 6.7e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HCLKBIDA_03714 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCLKBIDA_03720 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_03721 0.0 vicK 2.7.13.3 T Histidine kinase
HCLKBIDA_03722 3.2e-253 yycH S protein conserved in bacteria
HCLKBIDA_03723 4.4e-158 yycI S protein conserved in bacteria
HCLKBIDA_03724 4.8e-148 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HCLKBIDA_03725 2.3e-197 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HCLKBIDA_03726 1.7e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCLKBIDA_03727 8.3e-30
HCLKBIDA_03728 2.7e-17 V Abi-like protein
HCLKBIDA_03729 1.4e-38 L Transposase, Mutator family
HCLKBIDA_03730 5e-51 S amino acid activation for nonribosomal peptide biosynthetic process
HCLKBIDA_03733 5.1e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HCLKBIDA_03734 1.2e-63 L Transposase
HCLKBIDA_03735 2.3e-58 mhqP S DoxX
HCLKBIDA_03736 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCLKBIDA_03737 3.8e-139 est 3.1.1.1 S Carboxylesterase
HCLKBIDA_03738 7.1e-138 S COG1647 Esterase lipase
HCLKBIDA_03739 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCLKBIDA_03740 7.1e-28 secG U Preprotein translocase subunit SecG
HCLKBIDA_03741 1.7e-78 yclD
HCLKBIDA_03742 6.9e-265 S Tripartite tricarboxylate transporter TctA family
HCLKBIDA_03743 3.5e-69 S Tripartite tricarboxylate transporter TctB family
HCLKBIDA_03744 4.5e-164 S Tripartite tricarboxylate transporter family receptor
HCLKBIDA_03745 8.8e-223 4.2.1.158 M Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
HCLKBIDA_03746 1.4e-270 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCLKBIDA_03747 1.7e-173 dapAf2 4.3.3.7 EM Dihydrodipicolinate synthetase family
HCLKBIDA_03748 3.7e-120 MA20_15070 K FCD
HCLKBIDA_03749 3.3e-239 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCLKBIDA_03750 5.2e-300 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HCLKBIDA_03751 2.2e-128 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCLKBIDA_03752 4.1e-220 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HCLKBIDA_03753 1e-187 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCLKBIDA_03754 4.2e-181 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HCLKBIDA_03755 2.7e-202 S response regulator aspartate phosphatase
HCLKBIDA_03757 5.8e-39 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HCLKBIDA_03758 1.5e-234 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HCLKBIDA_03760 9.1e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCLKBIDA_03761 6.6e-234 E Peptidase dimerisation domain
HCLKBIDA_03762 1.5e-56 S Domain of unknown function (DUF4870)
HCLKBIDA_03763 3.5e-216 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HCLKBIDA_03764 8.7e-108 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HCLKBIDA_03765 1.5e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCLKBIDA_03766 8.7e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HCLKBIDA_03767 1.9e-37 crh G Phosphocarrier protein Chr
HCLKBIDA_03768 4.3e-178 whiA K May be required for sporulation
HCLKBIDA_03769 1.9e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HCLKBIDA_03770 5.2e-167 rapZ S Displays ATPase and GTPase activities
HCLKBIDA_03771 5.7e-91 yvcI 3.6.1.55 F Nudix hydrolase
HCLKBIDA_03772 5e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCLKBIDA_03773 8.7e-198 S COG0457 FOG TPR repeat
HCLKBIDA_03774 1.2e-161 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HCLKBIDA_03775 5e-63
HCLKBIDA_03776 1e-63 pcaC 3.1.1.24, 4.1.1.44 S Carboxymuconolactone decarboxylase family
HCLKBIDA_03777 0.0 2.2.1.6 EH Thiamine pyrophosphate enzyme, central domain
HCLKBIDA_03778 1.4e-186 S Oxidoreductase
HCLKBIDA_03779 2.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HCLKBIDA_03780 4.6e-39
HCLKBIDA_03781 2.7e-213 L Transposase
HCLKBIDA_03782 1.7e-69 rnhA 3.1.26.4 L An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
HCLKBIDA_03783 7.7e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCLKBIDA_03784 2.2e-94 ypsA S Belongs to the UPF0398 family
HCLKBIDA_03786 1.4e-228 yprB L RNase_H superfamily
HCLKBIDA_03787 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HCLKBIDA_03788 0.0 pepF E oligoendopeptidase F
HCLKBIDA_03789 6.4e-260 gerAA EG Spore germination protein
HCLKBIDA_03790 1.2e-189 gerAB E Spore germination protein
HCLKBIDA_03791 3.4e-208 gerAC S Spore germination B3/ GerAC like, C-terminal
HCLKBIDA_03792 4.4e-92
HCLKBIDA_03793 8.4e-116 mhqD S Carboxylesterase
HCLKBIDA_03794 1.4e-186 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HCLKBIDA_03795 1.3e-20
HCLKBIDA_03796 3.2e-153 ycsE S hydrolases of the HAD superfamily
HCLKBIDA_03797 1.1e-87
HCLKBIDA_03799 4.3e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCLKBIDA_03800 4e-65 kapB G Kinase associated protein B
HCLKBIDA_03801 4.5e-39
HCLKBIDA_03802 5e-113 ypjP S YpjP-like protein
HCLKBIDA_03803 7.8e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HCLKBIDA_03804 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HCLKBIDA_03805 2.7e-127 telA P Belongs to the TelA family
HCLKBIDA_03806 3.4e-169
HCLKBIDA_03807 1.4e-192 S Protein of unknown function (DUF2777)
HCLKBIDA_03808 1.7e-295 katB 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HCLKBIDA_03809 0.0 pepF2 E COG1164 Oligoendopeptidase F
HCLKBIDA_03810 1.2e-143
HCLKBIDA_03811 2.5e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HCLKBIDA_03812 5.8e-247 cydA 1.10.3.14 C oxidase, subunit
HCLKBIDA_03813 2.2e-21 S Fur-regulated basic protein B
HCLKBIDA_03816 4.1e-147 yfkD S YfkD-like protein
HCLKBIDA_03817 3.8e-220 yfkA S YfkB-like domain
HCLKBIDA_03818 5.5e-118 gpmB 5.4.2.11 G Belongs to the phosphoglycerate mutase family
HCLKBIDA_03819 2.5e-245 yhdP S COG1253 Hemolysins and related proteins containing CBS domains
HCLKBIDA_03820 1.9e-144 S Domain of unknown function (DUF368)
HCLKBIDA_03821 2.9e-150 pdaA G deacetylase
HCLKBIDA_03823 8.9e-167 ahpF 1.8.1.9 O Pyridine nucleotide-disulphide oxidoreductase
HCLKBIDA_03824 5.6e-71 ywgB K Transcriptional regulator
HCLKBIDA_03826 1.6e-61
HCLKBIDA_03827 9.4e-272 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCLKBIDA_03828 2.1e-204 mccF 3.4.17.13 V LD-carboxypeptidase
HCLKBIDA_03829 5.5e-49
HCLKBIDA_03830 2.5e-169 yfhF S nucleoside-diphosphate sugar epimerase
HCLKBIDA_03831 3.9e-145 recX 2.4.1.337 GT4 S Modulates RecA activity
HCLKBIDA_03832 5.2e-53 yfhH S Protein of unknown function (DUF1811)
HCLKBIDA_03833 1.2e-21 S YpzG-like protein
HCLKBIDA_03835 1.8e-189 yfhP S membrane-bound metal-dependent
HCLKBIDA_03836 1.9e-208 mutY L A G-specific
HCLKBIDA_03837 3.5e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_03838 4.1e-59
HCLKBIDA_03839 6.9e-19 yfhS
HCLKBIDA_03840 3.8e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HCLKBIDA_03841 5.4e-16 S Small, acid-soluble spore protein, gamma-type
HCLKBIDA_03842 1.5e-102 ygaC J Belongs to the UPF0374 family
HCLKBIDA_03843 0.0 ygaD V ABC transporter
HCLKBIDA_03844 7.5e-189 ygaE S Membrane
HCLKBIDA_03845 3e-248 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HCLKBIDA_03846 1.9e-88 bcp 1.11.1.15 O Peroxiredoxin
HCLKBIDA_03847 5.6e-183 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCLKBIDA_03848 2.7e-48 S Cyclic-di-AMP receptor
HCLKBIDA_03849 1.5e-79 perR P Belongs to the Fur family
HCLKBIDA_03850 3.6e-58 ygzB S UPF0295 protein
HCLKBIDA_03851 1.5e-18 bofA S Sigma-K factor-processing regulatory protein BofA
HCLKBIDA_03852 5.2e-31 S Protein of unknown function (DUF2508)
HCLKBIDA_03853 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCLKBIDA_03854 1.8e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCLKBIDA_03855 1.5e-308 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCLKBIDA_03856 1.7e-114 K Sigma-70, region 4
HCLKBIDA_03857 4.8e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCLKBIDA_03858 6.6e-87 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCLKBIDA_03859 4.9e-301 gsiB_4 E COG0747 ABC-type dipeptide transport system, periplasmic component
HCLKBIDA_03860 1.4e-159 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_03861 5.9e-169 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCLKBIDA_03862 7.4e-194 oppD P Belongs to the ABC transporter superfamily
HCLKBIDA_03863 2.6e-191 E Belongs to the ABC transporter superfamily
HCLKBIDA_03864 2.7e-129 glnQ2 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HCLKBIDA_03865 1.9e-110 glnP E Polar amino acid ABC transporter, inner membrane subunit
HCLKBIDA_03866 1.1e-144 glnH ET Ligated ion channel L-glutamate- and glycine-binding site
HCLKBIDA_03867 3.5e-63 S Bacterial PH domain
HCLKBIDA_03868 1.5e-269 gabD_2 1.2.1.9 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HCLKBIDA_03869 1.8e-195 hom2 1.1.1.3 E Homoserine dehydrogenase
HCLKBIDA_03870 2e-227 amaA 3.5.1.47 E Peptidase dimerisation domain
HCLKBIDA_03871 2.4e-228 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
HCLKBIDA_03872 1.4e-236 eutD 3.4.13.9, 3.5.4.44 E Creatinase/Prolidase N-terminal domain
HCLKBIDA_03874 6.1e-255 nhaC C Na H antiporter
HCLKBIDA_03875 2.7e-235 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HCLKBIDA_03876 1.1e-256 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HCLKBIDA_03877 0.0 QT COG2508 Regulator of polyketide synthase expression
HCLKBIDA_03878 7.4e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HCLKBIDA_03879 9.2e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCLKBIDA_03880 6.8e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HCLKBIDA_03881 2e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HCLKBIDA_03882 4.2e-151 yaaC S YaaC-like Protein
HCLKBIDA_03883 8.5e-290 E COG0747 ABC-type dipeptide transport system, periplasmic component
HCLKBIDA_03886 3.4e-07
HCLKBIDA_03887 1.5e-07
HCLKBIDA_03892 5.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HCLKBIDA_03893 4.9e-122 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HCLKBIDA_03894 4.8e-222 ybbR S protein conserved in bacteria
HCLKBIDA_03895 1.6e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCLKBIDA_03897 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCLKBIDA_03898 7.9e-154 ybfI K AraC-like ligand binding domain
HCLKBIDA_03899 2.2e-168 E Proline dehydrogenase
HCLKBIDA_03900 1.2e-199 V Beta-lactamase
HCLKBIDA_03902 1.1e-255 2.7.1.163 S Aminoglycoside phosphotransferase
HCLKBIDA_03903 6.3e-73 K SpoVT / AbrB like domain
HCLKBIDA_03904 9.7e-222 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HCLKBIDA_03905 1.1e-141 V ABC transporter, ATP-binding protein
HCLKBIDA_03906 0.0 V FtsX-like permease family
HCLKBIDA_03907 1.1e-121 T Transcriptional regulatory protein, C terminal
HCLKBIDA_03908 4.1e-192 T Histidine kinase-like ATPases
HCLKBIDA_03909 1.4e-102 K Bacterial regulatory proteins, tetR family
HCLKBIDA_03910 8.4e-222 mefE EGP Transmembrane secretion effector
HCLKBIDA_03911 0.0 V FtsX-like permease family
HCLKBIDA_03912 1.5e-84 V FtsX-like permease family
HCLKBIDA_03913 5.7e-138 V ABC transporter
HCLKBIDA_03914 1.8e-57 ytrA K GntR family transcriptional regulator
HCLKBIDA_03915 1.1e-161 V ABC transporter, ATP-binding protein
HCLKBIDA_03916 8.2e-100 S ABC-2 family transporter protein
HCLKBIDA_03917 1.3e-179 gluQ 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCLKBIDA_03919 1.8e-151 bla 3.5.2.6 V beta-lactamase
HCLKBIDA_03920 0.0 blaR 3.5.2.6 KTV BlaR1 peptidase M56
HCLKBIDA_03921 3.9e-63 blaI K Penicillinase repressor
HCLKBIDA_03922 1.9e-158 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HCLKBIDA_03923 0.0 K transcriptional regulator, MtlR
HCLKBIDA_03924 1.9e-68 2.3.1.128 J L-PSP family endoribonuclease
HCLKBIDA_03925 3.6e-235 3.1.3.41, 3.6.1.55 F Belongs to the Nudix hydrolase family
HCLKBIDA_03926 8.1e-72 phnB5 S 3-demethylubiquinone-9 3-methyltransferase
HCLKBIDA_03927 1.5e-74 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCLKBIDA_03928 2.7e-126 azlC E AzlC protein
HCLKBIDA_03929 2.7e-49 azlD E Branched-chain amino acid transport protein (AzlD)
HCLKBIDA_03930 3.4e-64 frataxin S Domain of unknown function (DU1801)
HCLKBIDA_03932 3e-56 smtB K helix_turn_helix, Arsenical Resistance Operon Repressor
HCLKBIDA_03933 3.9e-74 yndB K Activator of Hsp90 ATPase homolog 1-like protein
HCLKBIDA_03934 0.0 L ABC transporter
HCLKBIDA_03935 4.9e-128 1.14.12.17 C Oxidoreductase NAD-binding domain
HCLKBIDA_03936 4.9e-224 EGP Major facilitator Superfamily
HCLKBIDA_03937 5.7e-152 K ArsR family transcriptional regulator
HCLKBIDA_03938 4.3e-64 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCLKBIDA_03939 1.6e-199 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HCLKBIDA_03940 3.7e-117 ydhC K FCD
HCLKBIDA_03941 1.7e-167 catE 1.13.11.2 S glyoxalase
HCLKBIDA_03943 1e-239 oxdD 4.1.1.2 G Oxalate decarboxylase
HCLKBIDA_03946 5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HCLKBIDA_03947 1.3e-54 arsR K transcriptional
HCLKBIDA_03948 8e-79 carD K Transcription factor
HCLKBIDA_03949 5.1e-30 cspL K Cold shock
HCLKBIDA_03950 1e-170 mviM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HCLKBIDA_03951 4.3e-141 S TraX protein
HCLKBIDA_03952 2.5e-97 yrkC G Cupin domain
HCLKBIDA_03953 5e-60 Q ubiE/COQ5 methyltransferase family
HCLKBIDA_03954 8e-94 yokH G SMI1 / KNR4 family
HCLKBIDA_03955 2.9e-62 L Superfamily I DNA and RNA helicases
HCLKBIDA_03956 0.0 L AAA ATPase domain
HCLKBIDA_03957 3.7e-212 S homoserine kinase type II (protein kinase fold)
HCLKBIDA_03958 4.5e-140 2.7.1.89 M RIO1 family
HCLKBIDA_03959 3e-270 pbpE V Beta-lactamase
HCLKBIDA_03960 1.8e-142 K helix_turn_helix, mercury resistance
HCLKBIDA_03961 2.2e-96 2.7.1.48, 3.1.3.18 F uridine kinase
HCLKBIDA_03962 3.1e-69
HCLKBIDA_03963 4.6e-258 ypfE EGP Fungal trichothecene efflux pump (TRI12)
HCLKBIDA_03964 4.2e-77 nsrR3 K Transcriptional regulator
HCLKBIDA_03965 5.2e-110 K Bacterial transcriptional repressor C-terminal
HCLKBIDA_03966 3.4e-252 npr 1.11.1.1 P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCLKBIDA_03967 1.7e-09 S Enoyl-(Acyl carrier protein) reductase
HCLKBIDA_03968 3.5e-54 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCLKBIDA_03969 1.1e-230 eph 3.3.2.9 S Epoxide hydrolase N terminus
HCLKBIDA_03970 8e-171 S thiolester hydrolase activity
HCLKBIDA_03971 1.9e-83 yvmB1 K helix_turn_helix multiple antibiotic resistance protein
HCLKBIDA_03972 5.2e-66 J oxidation-reduction process
HCLKBIDA_03973 5.6e-283 yhjG CH FAD binding domain
HCLKBIDA_03974 2.1e-200 ybcL EGP Major facilitator Superfamily
HCLKBIDA_03975 6.7e-50 ybzH K Helix-turn-helix domain
HCLKBIDA_03976 1.9e-08 yhgE S Protein of unknown function (DUF3533)
HCLKBIDA_03978 0.0 yobO M Pectate lyase superfamily protein
HCLKBIDA_03986 1.5e-07
HCLKBIDA_03992 5.5e-144 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HCLKBIDA_03993 2.2e-198 araC2 K Arabinose-binding domain of AraC transcription regulator, N-term
HCLKBIDA_03994 7.9e-230 G Major Facilitator Superfamily
HCLKBIDA_03995 5.6e-77 nsrR K Transcriptional regulator
HCLKBIDA_03996 8.9e-242 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HCLKBIDA_03997 0.0 glpQ1 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HCLKBIDA_03998 3.5e-205 ugpC 3.6.3.20 P Belongs to the ABC transporter superfamily
HCLKBIDA_03999 1.2e-166 ugpA G ABC transporter (permease)
HCLKBIDA_04000 6.2e-143 ugpE P Glycerol-3-phosphate ABC transporter permease
HCLKBIDA_04001 4.6e-236 ugpB G Glycerol-3-phosphate ABC transporter substrate-binding protein
HCLKBIDA_04002 2e-143 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCLKBIDA_04003 7.4e-214 yceL EGP Major Facilitator Superfamily
HCLKBIDA_04004 0.0 G Bacterial extracellular solute-binding protein
HCLKBIDA_04005 1.4e-152 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HCLKBIDA_04006 6.5e-93 K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HCLKBIDA_04007 1.1e-175 G Binding-protein-dependent transport system inner membrane component
HCLKBIDA_04008 4.3e-158 G COG0395 ABC-type sugar transport system, permease component
HCLKBIDA_04009 6.3e-128 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCLKBIDA_04010 3.5e-182 G Xylose isomerase-like TIM barrel
HCLKBIDA_04011 5.1e-198 S Oxidoreductase family, C-terminal alpha/beta domain
HCLKBIDA_04012 2.4e-147 yjqC P Catalase
HCLKBIDA_04013 1.1e-107 E Lysine exporter protein LysE YggA
HCLKBIDA_04014 2.7e-244 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HCLKBIDA_04015 5.1e-116 yhcQ M Spore coat protein
HCLKBIDA_04017 2.7e-174 eutC 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
HCLKBIDA_04018 1.8e-173 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HCLKBIDA_04019 3.1e-210 mntH P H( )-stimulated, divalent metal cation uptake system
HCLKBIDA_04020 2.3e-116 S HTH domain
HCLKBIDA_04021 3.9e-189 speB 3.5.3.11 E Arginase family
HCLKBIDA_04022 2e-129 T Transcriptional regulator
HCLKBIDA_04023 1.1e-203 T PhoQ Sensor
HCLKBIDA_04024 2.2e-165 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HCLKBIDA_04025 4.2e-124 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HCLKBIDA_04026 1.5e-117 ydfE S Flavin reductase like domain
HCLKBIDA_04027 6.2e-115 S ABC-2 family transporter protein
HCLKBIDA_04028 1.9e-167 ycbN V ABC transporter, ATP-binding protein
HCLKBIDA_04029 2.7e-166 T PhoQ Sensor
HCLKBIDA_04030 9.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HCLKBIDA_04031 0.0 M Domain of unknown function DUF11
HCLKBIDA_04032 1.3e-81 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HCLKBIDA_04035 0.0 M cell wall anchor domain
HCLKBIDA_04036 1.8e-85 3.4.22.70 M Sortase family
HCLKBIDA_04037 2.2e-137 K helix_turn_helix, mercury resistance
HCLKBIDA_04038 3.8e-162 aacA-aphD 2.7.1.190 S Protein of unknown function (DUF1679)
HCLKBIDA_04039 1.1e-116 O Sap, sulfolipid-1-addressing protein
HCLKBIDA_04040 4e-72
HCLKBIDA_04041 1.2e-143 K MerR family transcriptional regulator
HCLKBIDA_04042 2.5e-166 K Acetyltransferase (GNAT) family
HCLKBIDA_04043 9.6e-190 MA20_01110 4.2.1.81 M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
HCLKBIDA_04044 3.2e-134 KT Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding
HCLKBIDA_04045 1e-112 S Protein of unknown function (DUF2812)
HCLKBIDA_04046 1.1e-47 padR K Transcriptional regulator PadR-like family
HCLKBIDA_04047 1.1e-53 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HCLKBIDA_04048 8.3e-24 K Helix-turn-helix domain
HCLKBIDA_04049 7.3e-72
HCLKBIDA_04050 1.8e-77 rimL 2.3.1.128 J Acetyltransferase (GNAT) domain
HCLKBIDA_04051 4.9e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HCLKBIDA_04052 5.3e-107 E GDSL-like Lipase/Acylhydrolase
HCLKBIDA_04053 8.4e-80 bcgIA 2.1.1.72 V Type II restriction modification enzyme methyltransferase
HCLKBIDA_04054 2.8e-135 bcgIA 2.1.1.72 V Type I restriction-modification system methyltransferase
HCLKBIDA_04055 3.6e-15 L PFAM Integrase, catalytic core
HCLKBIDA_04056 3.4e-165 I transferase activity, transferring acyl groups other than amino-acyl groups
HCLKBIDA_04057 7.8e-32
HCLKBIDA_04058 1.5e-116 S Sap, sulfolipid-1-addressing protein
HCLKBIDA_04059 3.8e-105 pksA K BetI-type transcriptional repressor, C-terminal
HCLKBIDA_04061 5e-131 MA20_20400 3.4.11.5 S Alpha/beta hydrolase family
HCLKBIDA_04063 4.2e-77 K Bacterial regulatory proteins, tetR family
HCLKBIDA_04064 2.8e-40 S Protein of unknown function (DUF4064)
HCLKBIDA_04065 7.4e-192 V penicillin-binding protein
HCLKBIDA_04066 3.5e-34 S Predicted integral membrane protein (DUF2269)
HCLKBIDA_04067 2.7e-142 blt5 EGP Major facilitator Superfamily
HCLKBIDA_04068 7.7e-134 S Conjugative transposon protein TcpC
HCLKBIDA_04069 1.1e-157 yddH M Lysozyme-like
HCLKBIDA_04070 5.5e-199 S the current gene model (or a revised gene model) may contain a frame shift
HCLKBIDA_04071 0.0 S AAA-like domain
HCLKBIDA_04072 1.2e-76 S glyoxalase bleomycin resistance protein dioxygenase
HCLKBIDA_04073 8.7e-205 C Na+/H+ antiporter family
HCLKBIDA_04074 5.9e-13 C Na+/H+ antiporter family
HCLKBIDA_04075 1.6e-185 ord 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
HCLKBIDA_04076 4.9e-168 K LysR substrate binding domain
HCLKBIDA_04077 1.7e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HCLKBIDA_04078 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCLKBIDA_04079 1.3e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HCLKBIDA_04080 4.9e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCLKBIDA_04081 2.6e-149 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HCLKBIDA_04082 1.1e-155 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HCLKBIDA_04083 5.6e-109 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HCLKBIDA_04084 3.3e-272 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCLKBIDA_04085 8.7e-173 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HCLKBIDA_04086 1.7e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCLKBIDA_04087 6.5e-142 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HCLKBIDA_04088 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCLKBIDA_04089 1.8e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HCLKBIDA_04090 1e-270 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCLKBIDA_04091 5.9e-177 KLT serine threonine protein kinase
HCLKBIDA_04092 4.6e-129 yabS S protein containing a von Willebrand factor type A (vWA) domain
HCLKBIDA_04093 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HCLKBIDA_04094 3.1e-224 citM C Citrate transporter
HCLKBIDA_04095 2.4e-50 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HCLKBIDA_04096 2.3e-110 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HCLKBIDA_04097 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HCLKBIDA_04098 1.7e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HCLKBIDA_04099 7.8e-44 S DNA alkylation repair protein
HCLKBIDA_04100 1.2e-219 I COG0657 Esterase lipase
HCLKBIDA_04101 4.3e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCLKBIDA_04102 5.1e-53 yneR S Belongs to the HesB IscA family
HCLKBIDA_04104 3.8e-162 cheV 2.7.13.3 T Chemotaxis protein CheV
HCLKBIDA_04105 4.4e-177 3.4.13.19 E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
HCLKBIDA_04106 1.5e-71 hspX O Belongs to the small heat shock protein (HSP20) family
HCLKBIDA_04107 2.3e-29 S YppG-like protein
HCLKBIDA_04108 7.9e-23
HCLKBIDA_04109 6.1e-235 ykuI T Diguanylate phosphodiesterase
HCLKBIDA_04110 3.3e-155 I Hydrolase
HCLKBIDA_04111 7.9e-179 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HCLKBIDA_04112 2e-80 S Domain of unknown function (DUF4352)
HCLKBIDA_04113 6.9e-156 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCLKBIDA_04114 2.9e-75 S thioesterase
HCLKBIDA_04115 0.0 spoVK O stage V sporulation protein K
HCLKBIDA_04116 1.8e-141 P Copper resistance protein D
HCLKBIDA_04117 1.2e-11 sspN S Small acid-soluble spore protein N family
HCLKBIDA_04119 1e-251 iucD_1 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
HCLKBIDA_04120 5.1e-259 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HCLKBIDA_04121 3.2e-112 rnhA 3.1.26.4 L Caulimovirus viroplasmin
HCLKBIDA_04122 1.4e-40
HCLKBIDA_04123 2e-46 abrB K SpoVT / AbrB like domain
HCLKBIDA_04124 3e-56
HCLKBIDA_04125 2.9e-238 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HCLKBIDA_04126 2.2e-182 mreB D Rod-share determining protein MreBH
HCLKBIDA_04127 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HCLKBIDA_04128 2.9e-165 fruB 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HCLKBIDA_04129 1e-134 fruR K Transcriptional regulator
HCLKBIDA_04130 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HCLKBIDA_04131 3.2e-211 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HCLKBIDA_04132 1.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HCLKBIDA_04133 1.2e-126 treR K transcriptional
HCLKBIDA_04134 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HCLKBIDA_04135 2.6e-156 yobV9 K transcriptional regulator
HCLKBIDA_04136 1.2e-117 yoaZ 3.5.1.124 S DJ-1/PfpI family
HCLKBIDA_04138 6.1e-129 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
HCLKBIDA_04139 5.1e-139 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HCLKBIDA_04140 8e-185 P ABC transporter substrate-binding protein
HCLKBIDA_04141 8e-162 E Glyoxalase-like domain
HCLKBIDA_04142 2e-144 MA20_35565 4.1.3.30 G Phosphoenolpyruvate phosphomutase
HCLKBIDA_04143 1.1e-113 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HCLKBIDA_04144 9.9e-45 sdpR K transcriptional
HCLKBIDA_04145 2.9e-165 K LysR substrate binding domain
HCLKBIDA_04146 8.4e-122 mdmC 2.1.1.104 S O-methyltransferase
HCLKBIDA_04147 5.7e-264 alsT E Sodium alanine symporter
HCLKBIDA_04148 6.3e-134 IQ Short-chain dehydrogenase reductase sdr
HCLKBIDA_04149 6.7e-81 S Bacterial PH domain
HCLKBIDA_04150 7.1e-104 K Bacterial regulatory proteins, tetR family
HCLKBIDA_04151 2e-202 C NADH:flavin oxidoreductase / NADH oxidase family
HCLKBIDA_04153 1.7e-212 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HCLKBIDA_04154 2.8e-120 K FCD
HCLKBIDA_04155 1.1e-215 yeaN P COG2807 Cyanate permease
HCLKBIDA_04156 1e-66 cdd_2 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
HCLKBIDA_04157 7.5e-88 V COG1680 Beta-lactamase class C and other penicillin binding proteins
HCLKBIDA_04158 7.6e-125 yybG S Pentapeptide repeat-containing protein
HCLKBIDA_04159 3.8e-45 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HCLKBIDA_04160 6.2e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCLKBIDA_04161 2.5e-50 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
HCLKBIDA_04162 6.4e-281 gmuD 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCLKBIDA_04163 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HCLKBIDA_04164 1.6e-90 K Bacterial transcription activator, effector binding domain
HCLKBIDA_04165 8.7e-84
HCLKBIDA_04166 1.1e-20 ypbG 2.7.1.2 GK ROK family
HCLKBIDA_04167 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HCLKBIDA_04168 8.4e-167 aadK G Streptomycin adenylyltransferase
HCLKBIDA_04169 4.7e-99
HCLKBIDA_04171 1.2e-26
HCLKBIDA_04176 8.4e-22 M COG3209 Rhs family protein
HCLKBIDA_04177 9.7e-32 S nucleotidyltransferase activity
HCLKBIDA_04178 9.7e-09 S nucleotidyltransferase activity
HCLKBIDA_04179 2.2e-32
HCLKBIDA_04181 4.4e-23
HCLKBIDA_04183 2.2e-18 K Putative DNA-binding domain
HCLKBIDA_04184 2.5e-96 K Abortive infection C-terminus
HCLKBIDA_04185 5.9e-25 M RHS Repeat
HCLKBIDA_04186 1e-32 yxiG
HCLKBIDA_04187 2.2e-67 S SMI1 / KNR4 family
HCLKBIDA_04188 1.8e-44 U LXG domain of WXG superfamily
HCLKBIDA_04189 7.9e-80 yokJ S SMI1 / KNR4 family (SUKH-1)
HCLKBIDA_04190 4.9e-54 1.1.98.6, 3.6.3.14, 3.6.3.15, 4.1.1.35 L intein-mediated protein splicing
HCLKBIDA_04191 1.7e-45
HCLKBIDA_04193 6.5e-81 K Bacterial regulatory proteins, tetR family
HCLKBIDA_04194 6.2e-88 yqeB
HCLKBIDA_04195 3.6e-69 S Protein of unknown function (DUF418)
HCLKBIDA_04196 1e-139 S Alpha/beta hydrolase family
HCLKBIDA_04197 3e-95 2.3.1.59 K Acetyltransferase (GNAT) domain
HCLKBIDA_04198 2.8e-151 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HCLKBIDA_04199 1.9e-61 S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCLKBIDA_04200 3.7e-51 M Peptidase family M23
HCLKBIDA_04201 1.3e-52 M Peptidase family M23
HCLKBIDA_04202 2.8e-198 L COG3547 Transposase and inactivated derivatives
HCLKBIDA_04203 1.1e-59 atl 3.2.1.96, 3.4.17.14, 3.5.1.28, 6.1.1.12 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCLKBIDA_04204 1.7e-07
HCLKBIDA_04212 6.7e-94 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
HCLKBIDA_04213 5.8e-82 L Transposase IS200 like

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)