ORF_ID e_value Gene_name EC_number CAZy COGs Description
APPPNAGC_00001 7.8e-63 S Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APPPNAGC_00002 2.6e-113 M Peptidase family M23
APPPNAGC_00004 1.8e-256 G Bacterial extracellular solute-binding protein
APPPNAGC_00005 6.7e-148 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_00006 1e-162 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_00007 7e-214 3.2.1.180 GH88 O Glycosyl Hydrolase Family 88
APPPNAGC_00008 1.6e-165 3.2.2.21 K AraC-like ligand binding domain
APPPNAGC_00009 1.7e-223 S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_00010 3.9e-209 S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_00011 7.5e-99 3.2.2.21 K AraC-like ligand binding domain
APPPNAGC_00012 6.4e-142 G Xylose isomerase-like TIM barrel
APPPNAGC_00013 1.8e-153 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_00014 2.3e-170 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_00015 1.5e-252 G Bacterial extracellular solute-binding protein
APPPNAGC_00016 1.2e-210 S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_00017 2.6e-140 G Xylose isomerase-like TIM barrel
APPPNAGC_00018 1.4e-170 3.2.2.21 K Cupin domain
APPPNAGC_00019 1.2e-188 S Oxidoreductase family, NAD-binding Rossmann fold
APPPNAGC_00020 1.5e-62 S Protein of unknown function, DUF393
APPPNAGC_00021 2.3e-135 yfhB 5.3.3.17 S PhzF family
APPPNAGC_00022 2.2e-105 V Beta-lactamase
APPPNAGC_00023 1.7e-91 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APPPNAGC_00024 2.2e-311 2.6.1.52 E Aminotransferase class-V
APPPNAGC_00025 0.0 ltaS 2.7.8.20 M Sulfatase
APPPNAGC_00026 4.8e-64 E lactoylglutathione lyase activity
APPPNAGC_00027 1.9e-150 3.5.1.28 M COG3103 SH3 domain protein
APPPNAGC_00028 4.3e-110 K LysR substrate binding domain
APPPNAGC_00029 9.1e-122 pkn1 1.8.3.7 S Sulfatase-modifying factor enzyme 1
APPPNAGC_00030 1.7e-102 5.1.3.9 G Putative N-acetylmannosamine-6-phosphate epimerase
APPPNAGC_00031 4.9e-47 2.7.1.201 G PTS system, glucose subfamily, IIA
APPPNAGC_00032 1.9e-205 atsG P Type I phosphodiesterase / nucleotide pyrophosphatase
APPPNAGC_00033 1.2e-214 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
APPPNAGC_00034 3.1e-85 K Regulates the succiny-lCoA synthetase operon
APPPNAGC_00035 2.1e-79 S Sulfite exporter TauE/SafE
APPPNAGC_00036 1.8e-154 htpX O Belongs to the peptidase M48B family
APPPNAGC_00037 2.3e-23 mcbG S Pentapeptide repeats (9 copies)
APPPNAGC_00038 4.9e-148 araQ P PFAM binding-protein-dependent transport systems inner membrane component
APPPNAGC_00039 2.4e-159 lacF G Binding-protein-dependent transport system inner membrane component
APPPNAGC_00040 8.1e-238 araN G ABC transporter substrate-binding protein
APPPNAGC_00041 3.9e-48 S Branched-chain amino acid transport protein (AzlD)
APPPNAGC_00042 4.7e-115 azlC E AzlC protein
APPPNAGC_00043 5.2e-96 ydcN K Helix-turn-helix XRE-family like proteins
APPPNAGC_00044 6.7e-87 M FR47-like protein
APPPNAGC_00046 2.9e-35 S membrane
APPPNAGC_00047 1.4e-90 S Peptidase M50
APPPNAGC_00048 8.3e-235 hisS 6.1.1.21 J histidyl-tRNA synthetase
APPPNAGC_00049 2.4e-113 ypgQ S phosphohydrolase
APPPNAGC_00050 7.6e-26
APPPNAGC_00051 2.3e-279 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase
APPPNAGC_00052 2.9e-204 S Protein of unknown function (DUF917)
APPPNAGC_00053 4e-213 codB_1 F cytosine purines uracil thiamine allantoin
APPPNAGC_00054 6.6e-102 K Bacterial regulatory proteins, tetR family
APPPNAGC_00055 2.1e-135 K acetyltransferase
APPPNAGC_00056 9.4e-81 S Stage II sporulation protein P (SpoIIP)
APPPNAGC_00057 4e-156 KLT Protein kinase domain
APPPNAGC_00058 1.4e-56 FG HIT domain
APPPNAGC_00059 1.2e-164 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
APPPNAGC_00060 1.1e-87
APPPNAGC_00062 2.4e-178 S COG1073 Hydrolases of the alpha beta superfamily
APPPNAGC_00063 8.4e-230 S protein conserved in bacteria
APPPNAGC_00064 8.6e-251 3.5.4.28, 3.5.4.31 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
APPPNAGC_00065 4.9e-219 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
APPPNAGC_00066 7.5e-239 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
APPPNAGC_00067 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
APPPNAGC_00068 2e-280 T COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
APPPNAGC_00069 4.4e-220 G Transmembrane secretion effector
APPPNAGC_00070 1e-183 desK 2.7.13.3 T Histidine kinase
APPPNAGC_00071 5.9e-106 K helix_turn_helix, Lux Regulon
APPPNAGC_00072 4.7e-117
APPPNAGC_00073 5.5e-155 licT K antiterminator
APPPNAGC_00074 3.5e-269 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
APPPNAGC_00075 1.7e-176 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
APPPNAGC_00076 1.7e-83 M Protein of unknown function (DUF1541)
APPPNAGC_00077 2.5e-47
APPPNAGC_00078 5.7e-297 expZ S ABC transporter
APPPNAGC_00079 9.3e-211 gatD 1.1.1.14 C Alcohol dehydrogenase GroES-like domain
APPPNAGC_00080 3.3e-21
APPPNAGC_00081 1.6e-196 gutB 1.1.1.1, 1.1.1.14 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APPPNAGC_00082 4.7e-214 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
APPPNAGC_00083 1.3e-42 gatB_1 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
APPPNAGC_00084 2.3e-81 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APPPNAGC_00085 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
APPPNAGC_00086 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
APPPNAGC_00087 2.9e-185
APPPNAGC_00088 9.7e-104 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
APPPNAGC_00089 1.4e-175 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
APPPNAGC_00090 3.1e-103 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
APPPNAGC_00091 1.6e-89 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
APPPNAGC_00092 5.3e-197 MA20_17100 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
APPPNAGC_00093 1e-84 G Tripartite ATP-independent periplasmic transporters, DctQ component
APPPNAGC_00094 6.2e-161 dctP_1 G Bacterial extracellular solute-binding protein, family 7
APPPNAGC_00095 3.1e-176 kdgR K transcriptional
APPPNAGC_00096 3.4e-52 K Transcriptional regulator PadR-like family
APPPNAGC_00097 4.7e-73
APPPNAGC_00098 2.2e-73
APPPNAGC_00099 1.2e-197 frvX 3.2.1.4 GH5,GH9 G M42 glutamyl aminopeptidase
APPPNAGC_00100 4.1e-41 S Membrane
APPPNAGC_00101 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
APPPNAGC_00102 1.3e-164 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
APPPNAGC_00103 1.9e-144 tagG GM Transport permease protein
APPPNAGC_00104 2.9e-137 S GNAT acetyltransferase
APPPNAGC_00105 0.0 3.6.3.8 P COG0474 Cation transport ATPase
APPPNAGC_00106 2.7e-61 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
APPPNAGC_00107 6.5e-193 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
APPPNAGC_00108 7.6e-26
APPPNAGC_00109 9.5e-299 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
APPPNAGC_00110 3.6e-33
APPPNAGC_00111 4.6e-125 P PFAM binding-protein-dependent transport systems inner membrane component
APPPNAGC_00112 8.5e-130 G ABC transporter permease
APPPNAGC_00113 5.4e-175 G Bacterial extracellular solute-binding protein
APPPNAGC_00114 5.5e-142 araR K transcriptional
APPPNAGC_00115 8.2e-129 modA P COG0725 ABC-type molybdate transport system, periplasmic component
APPPNAGC_00116 4.3e-110 modB P COG4149 ABC-type molybdate transport system, permease component
APPPNAGC_00117 1.6e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APPPNAGC_00118 1.2e-181 vraS 2.7.13.3 T Histidine kinase
APPPNAGC_00119 1.5e-124 yvqF S Cell wall-active antibiotics response 4TMS YvqF
APPPNAGC_00120 2.9e-103
APPPNAGC_00122 2.2e-113 4.4.1.3, 5.3.1.15 S Cupin
APPPNAGC_00123 0.0 DSE4 M glycoside hydrolase family 81
APPPNAGC_00124 3.5e-191 purR11 K helix_turn _helix lactose operon repressor
APPPNAGC_00125 1.4e-145 P PFAM binding-protein-dependent transport systems inner membrane component
APPPNAGC_00126 3.3e-156 P PFAM binding-protein-dependent transport systems inner membrane component
APPPNAGC_00127 1.5e-199 cebE G PFAM extracellular solute-binding protein family 1
APPPNAGC_00128 6.6e-117 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
APPPNAGC_00129 2.8e-290 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APPPNAGC_00130 1.5e-169 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_00131 1.7e-171 K WYL domain
APPPNAGC_00132 1.5e-109 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
APPPNAGC_00133 1.3e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APPPNAGC_00134 7.8e-150 czcD P COG1230 Co Zn Cd efflux system component
APPPNAGC_00135 1.3e-48 czrA K transcriptional
APPPNAGC_00136 7.1e-164 gltC K Transcriptional regulator
APPPNAGC_00137 6.8e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
APPPNAGC_00138 1.4e-86 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
APPPNAGC_00139 7.3e-121 S membrane
APPPNAGC_00140 1.8e-27 sspB S spore protein
APPPNAGC_00141 5.7e-29 sspB S spore protein
APPPNAGC_00142 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APPPNAGC_00144 4.6e-152 acrR_2 K Transcriptional regulator
APPPNAGC_00145 4.7e-126
APPPNAGC_00146 4.9e-162 V ATPases associated with a variety of cellular activities
APPPNAGC_00147 6.6e-60 gntR1 K helix_turn_helix gluconate operon transcriptional repressor
APPPNAGC_00148 9e-110 Q Methyltransferase domain
APPPNAGC_00149 2.5e-139 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
APPPNAGC_00151 4.7e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APPPNAGC_00152 1.5e-168 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
APPPNAGC_00153 2.2e-173 P Catalase
APPPNAGC_00154 3.2e-256 S Predicted membrane protein (DUF2254)
APPPNAGC_00155 1e-156 opuAC E Glycine betaine ABC transporter
APPPNAGC_00156 1.2e-241 yhdP S COG1253 Hemolysins and related proteins containing CBS domains
APPPNAGC_00157 5.7e-138 srtB 3.4.22.70 S Sortase family
APPPNAGC_00158 4.2e-133 fhuC 3.6.3.28, 3.6.3.34 HP ABC transporter, ATP-binding protein
APPPNAGC_00159 1.3e-166 fhuB11 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPPNAGC_00160 5.5e-156 isdE P ABC transporter substrate-binding protein
APPPNAGC_00161 7.3e-158 M Cell surface protein
APPPNAGC_00162 3.3e-105 isdC M NEAr Transporter domain
APPPNAGC_00163 7.6e-52 isdG 1.14.99.48, 1.14.99.57 C Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
APPPNAGC_00164 1.2e-172 fhuG 3.6.3.34 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPPNAGC_00165 1.1e-167 fhuD P Periplasmic binding protein
APPPNAGC_00166 1.9e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APPPNAGC_00167 2.5e-133 2.1.1.144, 2.1.1.197 S Methyltransferase domain
APPPNAGC_00168 9.1e-110 K Bacterial transcriptional repressor C-terminal
APPPNAGC_00169 7.5e-248 EGP Major facilitator Superfamily
APPPNAGC_00170 1.6e-214 EGP Major facilitator Superfamily
APPPNAGC_00171 1.2e-119 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
APPPNAGC_00172 3.5e-149 K LysR substrate binding domain
APPPNAGC_00173 9.9e-174 S Alpha/beta hydrolase family
APPPNAGC_00174 1.3e-148 5.1.3.22, 5.3.1.5 G Xylose isomerase-like TIM barrel
APPPNAGC_00175 3.1e-184 S Oxidoreductase family, NAD-binding Rossmann fold
APPPNAGC_00176 6.9e-184 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_00177 1.3e-145 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_00178 3.4e-169 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_00179 1.3e-240 cycB_2 G Bacterial extracellular solute-binding protein
APPPNAGC_00180 4.3e-217 GK ROK family
APPPNAGC_00181 4e-218 P Protein of unknown function (DUF418)
APPPNAGC_00182 4e-62 S YolD-like protein
APPPNAGC_00185 3.7e-282 K Mga helix-turn-helix domain
APPPNAGC_00186 2.6e-46
APPPNAGC_00187 6.3e-79 cwlM 3.5.1.28 M COG3103 SH3 domain protein
APPPNAGC_00188 0.0 clpE O Belongs to the ClpA ClpB family
APPPNAGC_00189 0.0 pepF E oligoendopeptidase
APPPNAGC_00190 7.6e-195 sstT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APPPNAGC_00191 1.1e-254
APPPNAGC_00192 1.3e-160 yjlA EG Putative multidrug resistance efflux transporter
APPPNAGC_00193 1e-176 isp O Belongs to the peptidase S8 family
APPPNAGC_00194 1.1e-123 yoqW S Belongs to the SOS response-associated peptidase family
APPPNAGC_00196 1e-162 V VanW like protein
APPPNAGC_00197 3.4e-71 V (ABC) transporter
APPPNAGC_00198 3.6e-52 K PadR family transcriptional regulator
APPPNAGC_00199 7.4e-113 yqeB
APPPNAGC_00200 5.2e-99 K Bacterial regulatory proteins, tetR family
APPPNAGC_00201 1.5e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APPPNAGC_00202 2e-277 murE 6.3.2.13 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APPPNAGC_00203 1.1e-86 M1-1022 1.8.5.2 S DoxX
APPPNAGC_00204 1.5e-22
APPPNAGC_00205 5.8e-61
APPPNAGC_00206 1.8e-108 K response regulator
APPPNAGC_00208 1.9e-156 S Membrane transport protein
APPPNAGC_00209 4.5e-193 G Xylose isomerase
APPPNAGC_00210 5.9e-141 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_00211 9.2e-167 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_00212 2.8e-208 cycB_1 G Bacterial extracellular solute-binding protein
APPPNAGC_00213 2.9e-179 S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_00214 5.5e-181 MA20_22185 K Transcriptional regulator, LacI family
APPPNAGC_00215 6.3e-55 S Ketosteroid isomerase-related protein
APPPNAGC_00216 8.6e-142 K Helix-turn-helix domain
APPPNAGC_00217 4.2e-170 fhuD P ABC transporter
APPPNAGC_00218 4.1e-150 dkgB S Aldo/keto reductase family
APPPNAGC_00219 5.6e-181 K helix_turn _helix lactose operon repressor
APPPNAGC_00220 1.4e-213 hemAT NT chemotaxis protein
APPPNAGC_00221 2.3e-129 S Nucleotidyltransferase domain
APPPNAGC_00222 4.6e-115 3.5.2.6 V beta-lactamase
APPPNAGC_00223 1.1e-116 tcpP 2.7.11.1 KT Forkhead associated domain
APPPNAGC_00224 4.8e-238 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
APPPNAGC_00225 3.1e-150 besA S Putative esterase
APPPNAGC_00226 4.5e-183 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPPNAGC_00227 4.4e-178 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPPNAGC_00228 9e-173 feuA P Iron-uptake system-binding protein
APPPNAGC_00229 7.5e-291 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
APPPNAGC_00230 3.2e-80 kipR K Transcriptional regulator
APPPNAGC_00231 7.2e-128 G Bacterial extracellular solute-binding protein, family 7
APPPNAGC_00232 7.8e-45 G Tripartite ATP-independent periplasmic transporters, DctQ component
APPPNAGC_00233 1.1e-178 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
APPPNAGC_00234 7.5e-177 ectD 1.14.11.55 Q Phytanoyl-CoA dioxygenase (PhyH)
APPPNAGC_00235 1.1e-151
APPPNAGC_00236 7.6e-245 gerKA EG Spore germination protein
APPPNAGC_00237 2.3e-177 gerKB E Spore germination protein
APPPNAGC_00238 1.1e-187 gerKC S Spore germination B3/ GerAC like, C-terminal
APPPNAGC_00239 0.0 bceB V ABC transporter (permease)
APPPNAGC_00240 3.5e-132 bceA V ABC transporter, ATP-binding protein
APPPNAGC_00241 1.3e-257 S Chlorophyllase enzyme
APPPNAGC_00242 8e-63 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APPPNAGC_00243 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
APPPNAGC_00244 5.3e-176 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APPPNAGC_00245 5.4e-44 ptxB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
APPPNAGC_00246 1.7e-203 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
APPPNAGC_00247 9.1e-153 4.1.2.13 G Fructose-bisphosphate aldolase class-II
APPPNAGC_00250 1.6e-102 3.5.1.124 S DJ-1/PfpI family
APPPNAGC_00252 9.6e-155 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylases
APPPNAGC_00253 3e-54 S Domain of unknown function (DUF4260)
APPPNAGC_00254 1e-64 K helix_turn_helix, mercury resistance
APPPNAGC_00255 1.9e-197 6.3.5.5 S ATP-grasp domain
APPPNAGC_00256 1.4e-206 dapE 3.5.1.18 E Peptidase dimerisation domain
APPPNAGC_00257 2.5e-92 S DinB superfamily
APPPNAGC_00263 1.3e-26 S response regulator aspartate phosphatase
APPPNAGC_00264 0.0 lacA 3.2.1.23 G beta-galactosidase
APPPNAGC_00265 6.4e-237 ganB 3.2.1.89 G arabinogalactan
APPPNAGC_00266 3.6e-146 ganQ P transport
APPPNAGC_00267 1.5e-239 malC P COG1175 ABC-type sugar transport systems, permease components
APPPNAGC_00268 6.5e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
APPPNAGC_00269 4.4e-183 lacR K Transcriptional regulator
APPPNAGC_00270 1.9e-150 yxxF EG EamA-like transporter family
APPPNAGC_00271 4.9e-148 K Transcriptional regulator
APPPNAGC_00272 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
APPPNAGC_00273 6.1e-148 XK27_01805 M Glycosyltransferase like family 2
APPPNAGC_00274 1.5e-91
APPPNAGC_00275 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
APPPNAGC_00276 0.0 3.2.1.21 GH3 G Belongs to the glycosyl hydrolase 3 family
APPPNAGC_00277 1.2e-112 gltC_1 K DNA-binding transcription factor activity
APPPNAGC_00278 1.2e-178 glf 5.4.99.9 M UDP-galactopyranose mutase
APPPNAGC_00279 1.2e-99 S ABC-2 family transporter protein
APPPNAGC_00280 7.2e-150 V ABC transporter
APPPNAGC_00281 3.4e-177 K Transcriptional regulator
APPPNAGC_00282 4.2e-186 3.5.3.6 E Amidinotransferase
APPPNAGC_00283 5.7e-256 putP E Sodium:solute symporter family
APPPNAGC_00284 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
APPPNAGC_00285 3.9e-166 NT chemotaxis protein
APPPNAGC_00286 2.9e-76 S Erythromycin esterase
APPPNAGC_00287 5.4e-125 S Erythromycin esterase
APPPNAGC_00288 6.6e-87 ykuD S protein conserved in bacteria
APPPNAGC_00289 4.4e-172 S Choline/ethanolamine kinase
APPPNAGC_00290 8.9e-61 K MerR, DNA binding
APPPNAGC_00291 4e-30 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APPPNAGC_00292 3.1e-102 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APPPNAGC_00293 1.3e-61 K Transcriptional regulator
APPPNAGC_00294 6.9e-75
APPPNAGC_00295 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
APPPNAGC_00296 6.3e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
APPPNAGC_00297 1e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
APPPNAGC_00298 1.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
APPPNAGC_00299 1.3e-154 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APPPNAGC_00300 1.2e-180 rbsR K transcriptional
APPPNAGC_00301 2.1e-174 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
APPPNAGC_00303 1.6e-37 comEA L Helix-hairpin-helix motif
APPPNAGC_00304 3.4e-253 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
APPPNAGC_00305 1.8e-124 T Transcriptional regulatory protein, C terminal
APPPNAGC_00306 1.6e-132
APPPNAGC_00307 3.1e-142 S ABC-2 family transporter protein
APPPNAGC_00308 1.8e-130 V AAA domain, putative AbiEii toxin, Type IV TA system
APPPNAGC_00309 5.2e-104 4.1.1.36, 6.3.2.5 H Flavoprotein
APPPNAGC_00310 5.8e-263 spaC1 V Lanthionine synthetase C-like protein
APPPNAGC_00311 0.0 spaB S Lantibiotic dehydratase, C terminus
APPPNAGC_00313 1.1e-172 XK27_06795 K sequence-specific DNA binding
APPPNAGC_00314 0.0 msbA2 3.6.3.44 V ABC transporter
APPPNAGC_00317 5e-54 K Helix-turn-helix XRE-family like proteins
APPPNAGC_00318 2.7e-98 3.4.22.70 M Sortase family
APPPNAGC_00319 0.0 M1-568 M cell wall anchor domain
APPPNAGC_00320 2.4e-81 T Response regulator containing CheY-like receiver and SARP domains
APPPNAGC_00321 7.9e-212 M1-573 T PhoQ Sensor
APPPNAGC_00322 5.7e-14
APPPNAGC_00323 5.6e-181 G phosphotransferase system
APPPNAGC_00324 8.1e-200 rspA 4.2.1.8 M Belongs to the mandelate racemase muconate lactonizing enzyme family
APPPNAGC_00325 1.1e-90 K Helix-turn-helix domain
APPPNAGC_00326 5.2e-24 uppS 2.5.1.31, 2.5.1.89 H Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids
APPPNAGC_00329 1e-137 yoaT S Protein of unknown function (DUF817)
APPPNAGC_00330 2.2e-29 K Transcriptional regulator
APPPNAGC_00331 7.8e-61 yoaS S membrane
APPPNAGC_00332 5.4e-103 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
APPPNAGC_00333 8.1e-55 yyaQ S Protein conserved in bacteria
APPPNAGC_00334 5.2e-156 kbaY 4.1.2.13, 4.1.2.40 G in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
APPPNAGC_00335 3.8e-193 gatD 1.1.1.14, 1.1.1.251 C Alcohol dehydrogenase GroES-like domain
APPPNAGC_00336 5.9e-239 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
APPPNAGC_00337 3.9e-41 gatB 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
APPPNAGC_00338 1.8e-78 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APPPNAGC_00339 6.2e-140 K COG1349 Transcriptional regulators of sugar metabolism
APPPNAGC_00340 3.3e-172 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
APPPNAGC_00341 2.9e-68 yqjY K Acetyltransferase (GNAT) domain
APPPNAGC_00342 4.8e-09
APPPNAGC_00343 9.9e-77
APPPNAGC_00344 5.2e-136 glvR K Helix-turn-helix domain, rpiR family
APPPNAGC_00345 5.7e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APPPNAGC_00346 2.8e-254 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APPPNAGC_00347 2e-258 C FAD dependent oxidoreductase
APPPNAGC_00348 2.3e-148 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_00349 1e-170 U Binding-protein-dependent transport system inner membrane component
APPPNAGC_00350 6.7e-245 G Bacterial extracellular solute-binding protein
APPPNAGC_00351 6.5e-307 2.7.13.3 T Histidine kinase
APPPNAGC_00352 3.4e-135 T helix_turn_helix, arabinose operon control protein
APPPNAGC_00353 1.7e-265 G beta-fructofuranosidase activity
APPPNAGC_00355 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
APPPNAGC_00356 2.2e-261 yeaV M Belongs to the BCCT transporter (TC 2.A.15) family
APPPNAGC_00358 1.4e-78 yiaB S yiaA/B two helix domain
APPPNAGC_00360 7.1e-32 cas2 L CRISPR associated protein Cas2
APPPNAGC_00361 3.2e-133 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
APPPNAGC_00362 3.4e-62 cas4 3.1.12.1 L Domain of unknown function DUF83
APPPNAGC_00363 2e-234 cas3 L DEAD-like helicases superfamily
APPPNAGC_00364 3.6e-75 cas5 L CRISPR-associated protein (Cas_Cas5)
APPPNAGC_00365 5.6e-113 cst2 L CRISPR-associated negative auto-regulator DevR/Csa2
APPPNAGC_00366 2.7e-159 cst1 S CRISPR-associated cxxc_cxxc protein Cst1
APPPNAGC_00367 6.4e-54 cas6 L CRISPR associated protein Cas6
APPPNAGC_00368 3.8e-89 yobV5 K Transcriptional regulator
APPPNAGC_00369 2.9e-10
APPPNAGC_00372 1.9e-09 K Transcriptional regulator
APPPNAGC_00375 4.9e-11 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
APPPNAGC_00376 4.2e-100 S Pfam:Peptidase_M78
APPPNAGC_00377 2.7e-07
APPPNAGC_00378 5.4e-157 S membrane
APPPNAGC_00379 1.2e-211 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
APPPNAGC_00381 3.3e-68 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
APPPNAGC_00382 9.2e-112 mucD 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APPPNAGC_00383 1.3e-60 yojF S Protein of unknown function (DUF1806)
APPPNAGC_00384 8.2e-125 bshB2 S deacetylase
APPPNAGC_00385 6.4e-165 polA 2.7.7.7 L Helix-hairpin-helix class 2 (Pol1 family) motifs
APPPNAGC_00386 9.4e-67 speG J Acetyltransferase (GNAT) domain
APPPNAGC_00387 4.7e-90 yocC
APPPNAGC_00388 8.5e-54 ytxJ O Protein of unknown function (DUF2847)
APPPNAGC_00389 0.0 recQ 3.6.4.12 L DNA helicase
APPPNAGC_00390 2.2e-156 S reductase
APPPNAGC_00391 4.4e-302 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APPPNAGC_00392 5.4e-32 yozC
APPPNAGC_00393 1e-176 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
APPPNAGC_00394 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
APPPNAGC_00396 1.7e-185 2.1.1.163, 2.1.1.201 Q O-methyltransferase
APPPNAGC_00397 1e-116 M lytic transglycosylase activity
APPPNAGC_00399 1.4e-72 osmC O redox protein, regulator of disulfide bond formation
APPPNAGC_00400 0.0 topB1 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APPPNAGC_00402 3.2e-167 V COG1131 ABC-type multidrug transport system, ATPase component
APPPNAGC_00403 6.4e-123 V ABC-2 type transporter
APPPNAGC_00404 1.9e-113 S ABC-2 type transporter
APPPNAGC_00405 2.4e-182 T Histidine kinase
APPPNAGC_00406 5.2e-102 KT LuxR family transcriptional regulator
APPPNAGC_00407 4.3e-94 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
APPPNAGC_00408 4.2e-119 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
APPPNAGC_00409 4.5e-76 queD 4.1.2.50, 4.2.3.12 H synthase
APPPNAGC_00410 1.1e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
APPPNAGC_00411 5.7e-233 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
APPPNAGC_00412 4.3e-245 agcS E Sodium alanine symporter
APPPNAGC_00413 1.4e-38 acyP 3.6.1.7 C Belongs to the acylphosphatase family
APPPNAGC_00414 9.6e-43 ywcE S Required for proper spore morphogenesis. Important for spore germination
APPPNAGC_00415 2.4e-50 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
APPPNAGC_00416 5.2e-110 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
APPPNAGC_00417 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APPPNAGC_00418 1.7e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
APPPNAGC_00419 1.7e-43 S DNA alkylation repair protein
APPPNAGC_00420 6.5e-210 I COG0657 Esterase lipase
APPPNAGC_00421 1.7e-87 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APPPNAGC_00422 1.1e-49 yneR S Belongs to the HesB IscA family
APPPNAGC_00424 1.5e-158 cheV 2.7.13.3 T Chemotaxis protein CheV
APPPNAGC_00425 1.3e-168 3.4.13.19 E COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
APPPNAGC_00426 5.3e-69 hspX O Belongs to the small heat shock protein (HSP20) family
APPPNAGC_00427 1.6e-25 S YppG-like protein
APPPNAGC_00428 1.7e-22
APPPNAGC_00429 1e-237 ykuI T Diguanylate phosphodiesterase
APPPNAGC_00430 3.6e-146 I Hydrolase
APPPNAGC_00431 2.3e-178 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
APPPNAGC_00432 1.7e-79 S Domain of unknown function (DUF4352)
APPPNAGC_00433 9.4e-153 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APPPNAGC_00434 2.9e-75 S thioesterase
APPPNAGC_00435 0.0 spoVK O stage V sporulation protein K
APPPNAGC_00436 2.2e-139 P Copper resistance protein D
APPPNAGC_00437 1.2e-11 sspN S Small acid-soluble spore protein N family
APPPNAGC_00440 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
APPPNAGC_00442 9.4e-13
APPPNAGC_00443 3.9e-81 yneK S Protein of unknown function (DUF2621)
APPPNAGC_00444 0.0 mdlB V COG1132 ABC-type multidrug transport system, ATPase and permease components
APPPNAGC_00445 0.0 mdlA V COG1132 ABC-type multidrug transport system, ATPase and permease components
APPPNAGC_00446 7.9e-29 yneF S UPF0154 protein
APPPNAGC_00447 2e-71 yneE S Sporulation inhibitor of replication protein sirA
APPPNAGC_00448 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APPPNAGC_00449 4.2e-34 ynzC S UPF0291 protein
APPPNAGC_00450 1.3e-114 yneB L resolvase
APPPNAGC_00452 2.6e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APPPNAGC_00453 2.7e-219 yuxJ EGP Major facilitator Superfamily
APPPNAGC_00455 3.3e-211 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APPPNAGC_00456 4.3e-92 MA20_21960 FG Domain of unknown function (DUF4269)
APPPNAGC_00457 1.8e-79
APPPNAGC_00458 2.8e-283 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
APPPNAGC_00459 3.4e-235 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
APPPNAGC_00460 2.6e-182 G MFS/sugar transport protein
APPPNAGC_00461 3.9e-115 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APPPNAGC_00462 7.7e-227 3.2.1.23 G beta-galactosidase
APPPNAGC_00463 8.2e-136 garR 1.1.1.60 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
APPPNAGC_00464 1.1e-58 K transcriptional regulator (AraC family)
APPPNAGC_00465 1.1e-94 G MFS/sugar transport protein
APPPNAGC_00466 2.5e-77 EH D-isomer specific 2-hydroxyacid dehydrogenase
APPPNAGC_00467 6.8e-128 K helix_turn_helix isocitrate lyase regulation
APPPNAGC_00468 1.8e-136 Q Domain of unknown function (DUF2437)
APPPNAGC_00469 0.0 glcB 2.3.3.9 C Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
APPPNAGC_00470 1.3e-271 glcD 1.1.2.4, 1.1.3.15 C FAD linked oxidases, C-terminal domain
APPPNAGC_00471 4.3e-250 glcF C Glycolate oxidase
APPPNAGC_00472 5e-243 glcE C FAD binding domain
APPPNAGC_00473 9e-264 glnA 6.3.1.2 E glutamine synthetase
APPPNAGC_00474 5.3e-245 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
APPPNAGC_00475 5.8e-169 spoVK O stage V sporulation protein K
APPPNAGC_00476 2.1e-183 xerD L Belongs to the 'phage' integrase family
APPPNAGC_00477 2.7e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
APPPNAGC_00478 1.9e-167 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APPPNAGC_00479 8.5e-134 J Putative SAM-dependent methyltransferase
APPPNAGC_00480 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APPPNAGC_00481 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APPPNAGC_00482 2.6e-103 cotE S Spore coat protein
APPPNAGC_00483 7.3e-55 ymcA 3.6.3.21 S Belongs to the UPF0342 family
APPPNAGC_00484 6.7e-303 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
APPPNAGC_00485 7.2e-152 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
APPPNAGC_00486 6.7e-38 spoVS S Stage V sporulation protein S
APPPNAGC_00487 6.7e-150 ymdB S protein conserved in bacteria
APPPNAGC_00488 1.8e-218 rny S Endoribonuclease that initiates mRNA decay
APPPNAGC_00489 5.8e-115 L DNA recombination
APPPNAGC_00491 1.4e-254 sbcC L AAA domain
APPPNAGC_00492 1.3e-187 L Calcineurin-like phosphoesterase superfamily domain
APPPNAGC_00493 3.3e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APPPNAGC_00494 5.7e-289 deaD 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APPPNAGC_00495 5.8e-225 cinA 3.5.1.42 S Belongs to the CinA family
APPPNAGC_00496 8.7e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APPPNAGC_00497 1.4e-124 ymfM S protein conserved in bacteria
APPPNAGC_00498 4.6e-140 ymfK S Protein of unknown function (DUF3388)
APPPNAGC_00499 1.3e-38 ymfJ S Protein of unknown function (DUF3243)
APPPNAGC_00500 7.2e-119 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_00501 1.2e-244 ymfH S zinc protease
APPPNAGC_00502 6.4e-227 ymfF S Peptidase M16
APPPNAGC_00503 4.9e-128 ymfC K Transcriptional regulator
APPPNAGC_00504 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
APPPNAGC_00505 8.4e-10 S YlzJ-like protein
APPPNAGC_00506 3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
APPPNAGC_00507 1.1e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APPPNAGC_00508 7e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APPPNAGC_00509 6.1e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
APPPNAGC_00510 1.8e-190 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APPPNAGC_00511 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
APPPNAGC_00512 3e-159 spoVFA E subunit a
APPPNAGC_00513 1.2e-35 ymxH S YlmC YmxH family
APPPNAGC_00514 9e-218 pepR S Belongs to the peptidase M16 family
APPPNAGC_00515 1e-187 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
APPPNAGC_00516 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
APPPNAGC_00517 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APPPNAGC_00518 8.8e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
APPPNAGC_00519 7.1e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APPPNAGC_00520 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APPPNAGC_00521 8.9e-41 ylxP S protein conserved in bacteria
APPPNAGC_00522 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APPPNAGC_00523 3.2e-47 ylxQ J ribosomal protein
APPPNAGC_00524 4.7e-42 ylxR K nucleic-acid-binding protein implicated in transcription termination
APPPNAGC_00525 5.2e-201 nusA K Participates in both transcription termination and antitermination
APPPNAGC_00526 9.6e-80 rimP S Required for maturation of 30S ribosomal subunits
APPPNAGC_00527 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APPPNAGC_00528 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APPPNAGC_00529 1.1e-228 rasP M zinc metalloprotease
APPPNAGC_00530 4.2e-206 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
APPPNAGC_00531 3.5e-130 cdsA 2.7.7.41 S Belongs to the CDS family
APPPNAGC_00532 2.4e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APPPNAGC_00533 2.1e-89 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APPPNAGC_00534 1.6e-123 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
APPPNAGC_00535 8.2e-149 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APPPNAGC_00536 1.5e-132 rpsB J Belongs to the universal ribosomal protein uS2 family
APPPNAGC_00538 4.9e-134 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APPPNAGC_00539 2.1e-82 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
APPPNAGC_00540 1.9e-104 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
APPPNAGC_00541 7.5e-161 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
APPPNAGC_00542 4.9e-94
APPPNAGC_00543 8.2e-174 flhF N Flagellar biosynthesis regulator FlhF
APPPNAGC_00544 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APPPNAGC_00545 1.4e-187 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APPPNAGC_00546 1.4e-128 fliR N Flagellar biosynthetic protein FliR
APPPNAGC_00547 3.6e-39 fliQ N Role in flagellar biosynthesis
APPPNAGC_00548 6.2e-112 fliP N Plays a role in the flagellum-specific transport system
APPPNAGC_00549 1.6e-104 fliZ N Flagellar biosynthesis protein, FliO
APPPNAGC_00550 1.2e-58 cheY T cheY-homologous receiver domain
APPPNAGC_00551 4.1e-204 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
APPPNAGC_00552 2e-175 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
APPPNAGC_00553 4.1e-69 fliL N Controls the rotational direction of flagella during chemotaxis
APPPNAGC_00554 1.5e-27 flbD N protein, possibly involved in motility
APPPNAGC_00555 2e-141 flgG N Flagellar basal body rod
APPPNAGC_00556 1.2e-71 flgD N Flagellar basal body rod modification protein
APPPNAGC_00557 3.8e-205 N Flagellar hook-length control protein FliK
APPPNAGC_00559 5.4e-40 fliJ N bacterial-type flagellum organization
APPPNAGC_00560 4.1e-245 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
APPPNAGC_00561 1.7e-73 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
APPPNAGC_00562 1.5e-175 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
APPPNAGC_00563 1.1e-241 fliF N The M ring may be actively involved in energy transduction
APPPNAGC_00564 1.8e-39 fliE N Flagellar hook-basal body
APPPNAGC_00565 1.8e-72 flgC N Belongs to the flagella basal body rod proteins family
APPPNAGC_00566 1.9e-65 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
APPPNAGC_00567 4.1e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
APPPNAGC_00568 9.4e-224 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
APPPNAGC_00569 2.3e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
APPPNAGC_00570 4.4e-166 xerC L tyrosine recombinase XerC
APPPNAGC_00571 2.1e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
APPPNAGC_00572 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APPPNAGC_00573 8.6e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
APPPNAGC_00574 9.7e-169 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
APPPNAGC_00575 5.3e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
APPPNAGC_00576 5.6e-75 ylqH S FlhB HrpN YscU SpaS Family
APPPNAGC_00577 2e-06 lig1
APPPNAGC_00578 2e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APPPNAGC_00580 3.4e-155 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APPPNAGC_00581 8.1e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
APPPNAGC_00583 7.2e-86 MA20_20600 1.14.17.3 CO amine dehydrogenase activity
APPPNAGC_00584 6.9e-121 6.3.5.6, 6.3.5.7 J amidotransferase, A subunit
APPPNAGC_00586 5.8e-74 mphE 4.1.2.52, 4.1.2.53 G Belongs to the HpcH HpaI aldolase family
APPPNAGC_00587 6.9e-209 aldHT_2 C Aldehyde dehydrogenase family
APPPNAGC_00588 1.6e-169 G Tripartite ATP-independent periplasmic transporter, DctM component
APPPNAGC_00589 2e-51 G Tripartite ATP-independent periplasmic transporters, DctQ component
APPPNAGC_00590 2.3e-118 G Bacterial extracellular solute-binding protein, family 7
APPPNAGC_00591 1.4e-154 E aminopeptidase
APPPNAGC_00592 4.1e-59 J YjgF/chorismate_mutase-like, putative endoribonuclease
APPPNAGC_00593 6.8e-122 kdgD 4.2.1.41 EM Dihydrodipicolinate synthetase family
APPPNAGC_00594 2.5e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APPPNAGC_00595 0.0 argS 6.1.1.19 J Arginyl tRNA synthetase N terminal dom
APPPNAGC_00596 1.4e-130 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
APPPNAGC_00597 4.2e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APPPNAGC_00598 1.5e-68 ylqD S YlqD protein
APPPNAGC_00599 2.5e-33 ylqC S Belongs to the UPF0109 family
APPPNAGC_00600 5.5e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
APPPNAGC_00601 2.5e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APPPNAGC_00602 3e-51 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APPPNAGC_00603 2.2e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APPPNAGC_00604 0.0 smc D Required for chromosome condensation and partitioning
APPPNAGC_00605 1.5e-09 yfkK S Belongs to the UPF0435 family
APPPNAGC_00606 4.4e-138 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APPPNAGC_00607 5.4e-31 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APPPNAGC_00608 5.7e-127 IQ reductase
APPPNAGC_00609 2.5e-167 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
APPPNAGC_00610 1.1e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APPPNAGC_00611 1.6e-97 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
APPPNAGC_00612 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APPPNAGC_00613 2.9e-146 sdaAA 4.3.1.17 E L-serine dehydratase
APPPNAGC_00614 4.6e-120 sdaAB 4.3.1.17 E L-serine dehydratase
APPPNAGC_00615 1.2e-147 degV3 S protein conserved in bacteria
APPPNAGC_00616 1.1e-300 yloV S kinase related to dihydroxyacetone kinase
APPPNAGC_00617 1.6e-58 asp S protein conserved in bacteria
APPPNAGC_00618 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
APPPNAGC_00619 2e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
APPPNAGC_00620 1e-162 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APPPNAGC_00621 0.0 KLT serine threonine protein kinase
APPPNAGC_00622 2.9e-131 stp 3.1.3.16 T phosphatase
APPPNAGC_00623 9.6e-258 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APPPNAGC_00624 3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APPPNAGC_00625 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APPPNAGC_00626 1.3e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APPPNAGC_00627 1.3e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APPPNAGC_00628 6.9e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
APPPNAGC_00629 3.5e-39 ylzA S Belongs to the UPF0296 family
APPPNAGC_00630 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
APPPNAGC_00631 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
APPPNAGC_00632 0.0 yfhO S Bacterial membrane protein YfhO
APPPNAGC_00634 6.1e-112 Q ubiE/COQ5 methyltransferase family
APPPNAGC_00635 1.2e-109 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APPPNAGC_00636 1.2e-121 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APPPNAGC_00637 2.9e-165 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APPPNAGC_00638 4.7e-140 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
APPPNAGC_00639 0.0 carB 6.3.5.5 F Belongs to the CarB family
APPPNAGC_00640 1.9e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APPPNAGC_00641 2.1e-238 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APPPNAGC_00642 8.7e-162 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
APPPNAGC_00643 1.3e-227 pyrP F Xanthine uracil
APPPNAGC_00644 7.5e-96 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APPPNAGC_00645 1.9e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APPPNAGC_00646 2.5e-72 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APPPNAGC_00647 2e-109 dksA T COG1734 DnaK suppressor protein
APPPNAGC_00648 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APPPNAGC_00649 1.8e-63 divIVA D Cell division initiation protein
APPPNAGC_00650 9e-136 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
APPPNAGC_00651 2e-43 yggT S membrane
APPPNAGC_00652 4.9e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APPPNAGC_00653 2.5e-116 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APPPNAGC_00654 2.8e-143 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
APPPNAGC_00655 1.7e-45 ylmC S sporulation protein
APPPNAGC_00656 6.2e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APPPNAGC_00657 1.1e-124 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APPPNAGC_00658 6.8e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
APPPNAGC_00659 9e-185 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APPPNAGC_00660 7.6e-220 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APPPNAGC_00662 1.8e-120 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APPPNAGC_00663 5.2e-185 spoVE D Belongs to the SEDS family
APPPNAGC_00664 3.3e-242 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APPPNAGC_00665 9.3e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APPPNAGC_00666 4.2e-245 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APPPNAGC_00667 1.3e-271 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APPPNAGC_00668 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
APPPNAGC_00670 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
APPPNAGC_00671 6e-47 ftsL D cell division protein FtsL
APPPNAGC_00672 1.1e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APPPNAGC_00673 2.6e-79 mraZ K Belongs to the MraZ family
APPPNAGC_00674 2.4e-303 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
APPPNAGC_00675 1e-10 S Protein of unknown function (DUF3397)
APPPNAGC_00676 2.2e-146 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APPPNAGC_00677 5.2e-92 ylbP K n-acetyltransferase
APPPNAGC_00678 3.6e-62 S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
APPPNAGC_00679 1.3e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
APPPNAGC_00680 6.4e-93 yceD S metal-binding, possibly nucleic acid-binding protein
APPPNAGC_00681 1.3e-221 ylbM S Belongs to the UPF0348 family
APPPNAGC_00682 3.9e-190 ylbL T Belongs to the peptidase S16 family
APPPNAGC_00683 5.8e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
APPPNAGC_00684 2.6e-214 ylbJ S Sporulation integral membrane protein YlbJ
APPPNAGC_00685 8e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APPPNAGC_00686 6e-97 rsmD 2.1.1.171 L Methyltransferase
APPPNAGC_00687 5.9e-64 S Methylthioribose kinase
APPPNAGC_00688 1.1e-46 ylbG S UPF0298 protein
APPPNAGC_00689 2.2e-57 ylbF S Belongs to the UPF0342 family
APPPNAGC_00690 1.5e-138 rimK1 HJ Prokaryotic glutathione synthetase, ATP-grasp domain
APPPNAGC_00691 1.2e-31 ylbE S YlbE-like protein
APPPNAGC_00692 1.3e-70 ylbD S Putative coat protein
APPPNAGC_00693 6.6e-84 yiiD Q protein, possibly involved in aromatic compounds catabolism
APPPNAGC_00694 5.6e-190 ylbC S protein with SCP PR1 domains
APPPNAGC_00695 6.1e-63 ylbA S YugN-like family
APPPNAGC_00696 6.7e-84
APPPNAGC_00697 5.7e-92 yozB S membrane
APPPNAGC_00698 1.8e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
APPPNAGC_00699 5.7e-104 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
APPPNAGC_00700 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APPPNAGC_00701 2.7e-199 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
APPPNAGC_00702 5.9e-158 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
APPPNAGC_00703 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
APPPNAGC_00704 9e-41 ylaN S Belongs to the UPF0358 family
APPPNAGC_00705 1.6e-91 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
APPPNAGC_00706 3.9e-251 phoH T ATPase related to phosphate starvation-inducible protein PhoH
APPPNAGC_00707 3.2e-32 ylaI S protein conserved in bacteria
APPPNAGC_00708 1.9e-50 ylaH S YlaH-like protein
APPPNAGC_00709 0.0 typA T GTP-binding protein TypA
APPPNAGC_00710 3.9e-162 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
APPPNAGC_00711 9.5e-152 suhB 3.1.3.25 G Inositol monophosphatase
APPPNAGC_00712 2.8e-114 yktB S Belongs to the UPF0637 family
APPPNAGC_00713 1.3e-38 yktA S Belongs to the UPF0223 family
APPPNAGC_00714 4.6e-277 speA 4.1.1.19 E Arginine
APPPNAGC_00715 4.9e-198 legA 3.5.1.2 O Peptidase family M48
APPPNAGC_00716 1.4e-121 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
APPPNAGC_00717 6.6e-277 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
APPPNAGC_00718 3.2e-65 CO cell redox homeostasis
APPPNAGC_00719 2.3e-162 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_00720 6.8e-173 P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_00721 0.0 appA_2 E COG0747 ABC-type dipeptide transport system, periplasmic component
APPPNAGC_00722 1.2e-185 E Belongs to the ABC transporter superfamily
APPPNAGC_00723 2.8e-185 oppD P Belongs to the ABC transporter superfamily
APPPNAGC_00724 2.2e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APPPNAGC_00725 2.6e-180 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APPPNAGC_00726 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APPPNAGC_00727 1.1e-201 bkdA1 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APPPNAGC_00728 8.1e-69 recN L Putative cell-wall binding lipoprotein
APPPNAGC_00730 3.4e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APPPNAGC_00731 9.1e-30 ykzG S Belongs to the UPF0356 family
APPPNAGC_00732 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APPPNAGC_00733 1.1e-113 ktrA P COG0569 K transport systems, NAD-binding component
APPPNAGC_00734 4.1e-83 ykuV CO thiol-disulfide
APPPNAGC_00735 4.7e-102 ykuU O Alkyl hydroperoxide reductase
APPPNAGC_00736 1.9e-125 ykuT M Mechanosensitive ion channel
APPPNAGC_00737 1.1e-91 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
APPPNAGC_00738 1.5e-183 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_00739 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APPPNAGC_00740 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APPPNAGC_00741 3e-10 yaaB S Domain of unknown function (DUF370)
APPPNAGC_00742 4e-201 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APPPNAGC_00743 7.7e-32 yaaA S S4 domain
APPPNAGC_00744 2.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APPPNAGC_00745 4.5e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APPPNAGC_00746 2.4e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
APPPNAGC_00747 2.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APPPNAGC_00748 2.5e-126 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APPPNAGC_00749 1e-108 jag S single-stranded nucleic acid binding R3H
APPPNAGC_00750 8.6e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APPPNAGC_00751 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APPPNAGC_00752 1.4e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
APPPNAGC_00753 8.8e-148 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
APPPNAGC_00754 1.3e-134 soj D COG1192 ATPases involved in chromosome partitioning
APPPNAGC_00755 3.9e-151 spo0J K Belongs to the ParB family
APPPNAGC_00756 3.3e-214 sufS 2.8.1.7, 4.4.1.16 E Aminotransferase class-V
APPPNAGC_00757 2.3e-113 yyaC S Sporulation protein YyaC
APPPNAGC_00758 4.9e-174 yyaD S Membrane
APPPNAGC_00759 1.8e-27 yyzM S protein conserved in bacteria
APPPNAGC_00760 4.5e-194 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APPPNAGC_00761 6.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
APPPNAGC_00762 4e-57 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APPPNAGC_00763 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APPPNAGC_00764 1.9e-145 yybS S membrane
APPPNAGC_00765 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
APPPNAGC_00766 4.2e-53 rplI J binds to the 23S rRNA
APPPNAGC_00767 2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
APPPNAGC_00768 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APPPNAGC_00774 5.1e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_00775 0.0 vicK 2.7.13.3 T Histidine kinase
APPPNAGC_00776 1e-243 yycH S protein conserved in bacteria
APPPNAGC_00777 1.7e-154 yycI S protein conserved in bacteria
APPPNAGC_00778 1.1e-147 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
APPPNAGC_00779 2.3e-197 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APPPNAGC_00780 1.2e-07 S YyzF-like protein
APPPNAGC_00781 1.7e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APPPNAGC_00782 2e-129 L AAA ATPase domain
APPPNAGC_00783 2.6e-59 V endonuclease activity
APPPNAGC_00787 2.2e-21
APPPNAGC_00790 3.4e-14
APPPNAGC_00791 5.3e-240 S Putative nucleotide-binding of sugar-metabolising enzyme
APPPNAGC_00792 1e-108 K FCD domain
APPPNAGC_00793 4e-187 1.1.1.14 E Dehydrogenase
APPPNAGC_00794 1.3e-182 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
APPPNAGC_00795 3.6e-72 siaT_3 G Tripartite ATP-independent periplasmic transporters, DctQ component
APPPNAGC_00796 5.1e-208 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
APPPNAGC_00797 6.4e-122 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
APPPNAGC_00798 0.0 pspF K PTS system fructose IIA component
APPPNAGC_00799 2.6e-197 M SIS domain
APPPNAGC_00800 4.9e-135 G PFAM Phosphotransferase system, mannose fructose sorbose family IID component
APPPNAGC_00801 1.5e-101 G PTS system sorbose-specific iic component
APPPNAGC_00802 4.8e-79 2.7.1.191 G PTS system mannose fructose sorbose family
APPPNAGC_00803 5.5e-71 2.7.1.191 G PTS system fructose IIA component
APPPNAGC_00804 6.9e-145 V ABC transporter
APPPNAGC_00805 3.9e-111 S ABC-2 family transporter protein
APPPNAGC_00807 2.7e-07
APPPNAGC_00808 2e-130 Z012_10580 S Sulfite exporter TauE/SafE
APPPNAGC_00810 0.0 oppA5 E Bacterial extracellular solute-binding proteins, family 5 Middle
APPPNAGC_00811 4.8e-171 appB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_00812 2.8e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_00813 5.5e-178 oppD3 P Belongs to the ABC transporter superfamily
APPPNAGC_00814 5.6e-183 oppF3 E Belongs to the ABC transporter superfamily
APPPNAGC_00815 4.4e-181 S domain protein
APPPNAGC_00816 0.0 ydfJ S MMPL family
APPPNAGC_00817 5.5e-101 K Transcriptional regulator
APPPNAGC_00818 8.8e-78
APPPNAGC_00819 1.7e-108 S CGNR zinc finger
APPPNAGC_00820 4.7e-73 S Domain of unknown function (DU1801)
APPPNAGC_00821 2e-154 S Domain of unknown function (DUF4179)
APPPNAGC_00822 9.3e-95 sigV K Belongs to the sigma-70 factor family. ECF subfamily
APPPNAGC_00823 1.9e-86 paiA K Acetyltransferase (GNAT) domain
APPPNAGC_00824 7.6e-251 NT chemotaxis protein
APPPNAGC_00825 8.4e-193 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
APPPNAGC_00826 2e-118 K FCD
APPPNAGC_00827 5.8e-183 G Bacterial extracellular solute-binding protein, family 7
APPPNAGC_00828 2.5e-75 G Tripartite ATP-independent periplasmic transporters, DctQ component
APPPNAGC_00829 2.6e-204 siaM G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
APPPNAGC_00830 9e-190 citA 2.3.3.1 C Belongs to the citrate synthase family
APPPNAGC_00831 9.9e-155 K Transcriptional regulator
APPPNAGC_00832 5.5e-186 S NMT1-like family
APPPNAGC_00833 0.0 S Tripartite ATP-independent periplasmic transporter, DctM component
APPPNAGC_00834 2.3e-117 K FCD
APPPNAGC_00835 1.6e-115 K COG2186 Transcriptional regulators
APPPNAGC_00836 1.2e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
APPPNAGC_00837 4.1e-220 glcF C Glycolate oxidase
APPPNAGC_00838 3.6e-224 lhgO 1.1.99.2 S FAD dependent oxidoreductase
APPPNAGC_00839 3.7e-280 QT COG2508 Regulator of polyketide synthase expression
APPPNAGC_00840 7.8e-222 codB F cytosine purines uracil thiamine allantoin
APPPNAGC_00841 1.8e-242 codA 3.5.4.1 F Amidohydrolase family
APPPNAGC_00842 1.7e-262 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
APPPNAGC_00843 6.9e-149 G COG2182 Maltose-binding periplasmic proteins domains
APPPNAGC_00844 5.4e-173 malC P COG1175 ABC-type sugar transport systems, permease components
APPPNAGC_00845 6.9e-129 malG P transport
APPPNAGC_00846 3.2e-264 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G Bacterial pullanase-associated domain
APPPNAGC_00847 2.6e-186 malR 5.1.1.1 K Transcriptional regulator
APPPNAGC_00848 9.2e-237 atoE I Short chain fatty acid transporter
APPPNAGC_00849 8.1e-131 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
APPPNAGC_00850 1.8e-113 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
APPPNAGC_00851 0.0 ubiD 4.1.1.98 H Belongs to the UbiD family
APPPNAGC_00852 9.3e-186 mhqA E COG0346 Lactoylglutathione lyase and related lyases
APPPNAGC_00853 1.9e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
APPPNAGC_00854 5.9e-227 yciC S GTPases (G3E family)
APPPNAGC_00855 5.6e-40 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APPPNAGC_00856 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APPPNAGC_00857 1.6e-146 degV S protein conserved in bacteria
APPPNAGC_00858 1e-105 S DUF218 domain
APPPNAGC_00859 1.5e-53 K Transcriptional regulator
APPPNAGC_00860 3.5e-107 M1-1017 S Protein of unknown function (DUF1129)
APPPNAGC_00861 9.7e-12
APPPNAGC_00862 7.7e-32
APPPNAGC_00864 3.4e-187 P COG2807 Cyanate permease
APPPNAGC_00865 1.7e-179 S amine dehydrogenase activity
APPPNAGC_00866 1.8e-119 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_00867 1.7e-252 T Histidine kinase
APPPNAGC_00868 7.7e-68 S YtkA-like
APPPNAGC_00869 1.1e-57 eaeH M LysM domain
APPPNAGC_00870 2e-45 phhB 3.5.4.33, 4.2.1.96 H pterin-4-alpha-carbinolamine dehydratase
APPPNAGC_00871 7.8e-236 S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APPPNAGC_00872 1e-134 ubiE Q Methyltransferase type 11
APPPNAGC_00873 8.5e-99 GBS0088 S protein conserved in bacteria
APPPNAGC_00874 9.9e-217 EGP Major facilitator Superfamily
APPPNAGC_00875 2e-26 sdpI S integral membrane protein
APPPNAGC_00878 1.8e-224 braB E Component of the transport system for branched-chain amino acids
APPPNAGC_00879 7e-59 S CHY zinc finger
APPPNAGC_00880 7.8e-166 rihB 3.2.2.1 F nucleoside hydrolase
APPPNAGC_00881 1.2e-114 idi I COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
APPPNAGC_00882 9.3e-292 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APPPNAGC_00883 9.7e-127 T COG4565 Response regulator of citrate malate metabolism
APPPNAGC_00884 5.6e-300 sdcS P Sodium:sulfate symporter transmembrane region
APPPNAGC_00885 1.6e-109 lolD V ABC transporter
APPPNAGC_00886 0.0
APPPNAGC_00888 0.0 2.7.13.3 T Histidine kinase
APPPNAGC_00890 2.2e-197 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APPPNAGC_00891 6e-137 S GNAT acetyltransferase
APPPNAGC_00892 1.2e-67
APPPNAGC_00893 6.5e-66
APPPNAGC_00894 4.9e-296
APPPNAGC_00895 3.3e-110
APPPNAGC_00896 5.1e-22
APPPNAGC_00897 9.2e-89
APPPNAGC_00898 5.2e-75 yosT L Bacterial transcription activator, effector binding domain
APPPNAGC_00899 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APPPNAGC_00900 3.4e-103 K GrpB protein
APPPNAGC_00901 3.5e-166 O Predicted Zn-dependent protease (DUF2268)
APPPNAGC_00902 8.8e-131 mta K TipAS antibiotic-recognition domain
APPPNAGC_00903 5.3e-22
APPPNAGC_00905 8.7e-162 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
APPPNAGC_00906 3.4e-107 yrbG3 S membrane
APPPNAGC_00907 1.1e-107 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
APPPNAGC_00908 2.4e-170 murB 1.3.1.98 M cell wall formation
APPPNAGC_00909 0.0 ywjA V ABC transporter
APPPNAGC_00910 4.5e-311 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
APPPNAGC_00911 3.2e-95 S DinB superfamily
APPPNAGC_00912 1.6e-211 yxlH EGP Major facilitator Superfamily
APPPNAGC_00913 0.0 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APPPNAGC_00914 1.5e-238 NT chemotaxis protein
APPPNAGC_00915 6.4e-218 S Acetyltransferase
APPPNAGC_00916 5.4e-248 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
APPPNAGC_00917 2.2e-145 ycsE 3.1.3.104 S hydrolases of the HAD superfamily
APPPNAGC_00919 1.4e-173 troA P Belongs to the bacterial solute-binding protein 9 family
APPPNAGC_00920 4.6e-140 troB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
APPPNAGC_00921 1.4e-159 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
APPPNAGC_00922 9.7e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
APPPNAGC_00923 3.7e-99 S UPF0302 domain
APPPNAGC_00924 8.7e-54 yflT S Heat induced stress protein YflT
APPPNAGC_00925 2.2e-42 ydzA EGP Major facilitator Superfamily
APPPNAGC_00926 1.3e-221 ywbD 2.1.1.191 J Methyltransferase
APPPNAGC_00927 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APPPNAGC_00928 1.4e-245 3.1.3.1 P Belongs to the alkaline phosphatase family
APPPNAGC_00929 1.2e-129 map 3.4.11.18 E Methionine aminopeptidase
APPPNAGC_00930 9.1e-153 yuaG 3.4.21.72 S protein conserved in bacteria
APPPNAGC_00931 1.9e-81 yuaF OU Membrane protein implicated in regulation of membrane protease activity
APPPNAGC_00933 3.2e-286 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
APPPNAGC_00934 1e-69 bdbC O Required for disulfide bond formation in some proteins
APPPNAGC_00935 6.6e-73 bdbA CO Thioredoxin
APPPNAGC_00936 3.9e-260 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APPPNAGC_00937 1.7e-76 K Acetyltransferase (GNAT) domain
APPPNAGC_00938 5.6e-72 S Protein of unknown function (DUF4064)
APPPNAGC_00939 1.2e-263 6.3.1.2 E Glutamine synthetase, catalytic domain
APPPNAGC_00940 6.7e-192 I Fatty acid desaturase
APPPNAGC_00941 4.6e-235 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E methionine gamma-lyase
APPPNAGC_00942 5.8e-129 S B3/4 domain
APPPNAGC_00943 1.1e-278 gntR9 K Alanine-glyoxylate amino-transferase
APPPNAGC_00944 1.1e-119 azlC E AzlC protein
APPPNAGC_00945 3.4e-47 S Branched-chain amino acid transport protein (AzlD)
APPPNAGC_00946 1.4e-273 hutH 4.3.1.3 E Histidine ammonia-lyase
APPPNAGC_00947 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APPPNAGC_00948 9.1e-232 BH2250 S protein conserved in bacteria
APPPNAGC_00949 8.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APPPNAGC_00950 7.1e-176 abrB S Pfam:AmoA
APPPNAGC_00951 2.5e-228 amtB P Ammonium transporter
APPPNAGC_00952 1.4e-167 2.7.7.7 T Putative nucleotidyltransferase substrate binding domain
APPPNAGC_00953 3.3e-132 dnaQ2 2.7.7.7 L COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
APPPNAGC_00954 5.2e-47 S Family of unknown function (DUF5327)
APPPNAGC_00955 4.3e-267 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APPPNAGC_00956 1.7e-108 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APPPNAGC_00957 1.3e-58 ywdK S small membrane protein
APPPNAGC_00958 9.8e-77 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
APPPNAGC_00959 2.4e-77 cwlJ 3.5.1.28 M Cell wall
APPPNAGC_00960 2.8e-101 msbA2 3.6.3.44 V ABC transporter
APPPNAGC_00961 1.8e-08 V ABC transporter
APPPNAGC_00962 6.8e-125
APPPNAGC_00963 2.6e-62 K helix_turn_helix gluconate operon transcriptional repressor
APPPNAGC_00964 1.1e-158 natA1 V ABC transporter
APPPNAGC_00965 5.4e-164 yhaQ S ABC transporter, ATP-binding protein
APPPNAGC_00966 2.6e-180 yhaP CP COG1668 ABC-type Na efflux pump, permease component
APPPNAGC_00967 5.8e-48
APPPNAGC_00968 1.7e-132 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APPPNAGC_00969 1.4e-144 ywfI C May function as heme-dependent peroxidase
APPPNAGC_00970 3.6e-140 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
APPPNAGC_00971 1.4e-181 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
APPPNAGC_00972 1.4e-142 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
APPPNAGC_00973 7.2e-191 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APPPNAGC_00974 5e-248 ywfO S COG1078 HD superfamily phosphohydrolases
APPPNAGC_00975 5e-90 ywgA 2.1.1.72, 3.1.21.3
APPPNAGC_00977 3.3e-44 cotF M Spore coat protein
APPPNAGC_00978 5.6e-26 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
APPPNAGC_00979 1.2e-123 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
APPPNAGC_00980 4.7e-189 F S-adenosylhomocysteine deaminase activity
APPPNAGC_00981 1.2e-97 ywhD S YwhD family
APPPNAGC_00982 0.0 pepF E oligoendopeptidase F
APPPNAGC_00983 7.1e-155 vipF 2.3.1.128 K Acetyltransferase (GNAT) domain
APPPNAGC_00984 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APPPNAGC_00985 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
APPPNAGC_00986 2.3e-167 speB 3.5.3.11 E Belongs to the arginase family
APPPNAGC_00987 5.5e-74 ywiB S protein conserved in bacteria
APPPNAGC_00988 2.6e-305 argS 6.1.1.19 J Arginyl-tRNA synthetase
APPPNAGC_00989 4.4e-72 yqgC S protein conserved in bacteria
APPPNAGC_00990 1.6e-216 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
APPPNAGC_00991 0.0 fadF C COG0247 Fe-S oxidoreductase
APPPNAGC_00992 2.1e-208 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
APPPNAGC_00993 1.5e-147 hbdA 1.1.1.157 I Dehydrogenase
APPPNAGC_00994 2.5e-206 mmgC I acyl-CoA dehydrogenase
APPPNAGC_00995 1.1e-107 kstR2_2 K Transcriptional regulator
APPPNAGC_00996 1.1e-57 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APPPNAGC_00997 5.4e-308 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APPPNAGC_00998 4e-87 ywjG S Domain of unknown function (DUF2529)
APPPNAGC_00999 5.5e-59 spo0F T response regulator
APPPNAGC_01000 3.8e-159 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
APPPNAGC_01001 2.8e-114 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
APPPNAGC_01002 9.6e-207 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APPPNAGC_01003 9.2e-178 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
APPPNAGC_01004 1.3e-235 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
APPPNAGC_01005 3.8e-40 rpmE2 J Ribosomal protein L31
APPPNAGC_01006 9.3e-109 tdk 2.7.1.21 F thymidine kinase
APPPNAGC_01007 9.3e-74
APPPNAGC_01008 1.8e-253 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
APPPNAGC_01009 9.6e-176 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APPPNAGC_01010 1.7e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APPPNAGC_01011 1.4e-113 spoIIR S stage II sporulation protein R
APPPNAGC_01012 4.4e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
APPPNAGC_01013 2.4e-179 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APPPNAGC_01014 5.9e-61 S Regulator of ribonuclease activity B
APPPNAGC_01015 1.4e-90 mntP P Probably functions as a manganese efflux pump
APPPNAGC_01016 2.2e-70 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APPPNAGC_01017 3.8e-118 mcpA NT Chemotaxis
APPPNAGC_01018 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
APPPNAGC_01019 3e-93 ywlG S Belongs to the UPF0340 family
APPPNAGC_01020 8.2e-235 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APPPNAGC_01021 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APPPNAGC_01022 5.7e-88 panZ K -acetyltransferase
APPPNAGC_01023 0.0 vpr O Belongs to the peptidase S8 family
APPPNAGC_01024 5.7e-22 atpI S Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
APPPNAGC_01025 7.3e-12 S ATP synthase I chain
APPPNAGC_01026 5.3e-130 atpB C it plays a direct role in the translocation of protons across the membrane
APPPNAGC_01027 1.4e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APPPNAGC_01028 1.3e-31 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APPPNAGC_01029 2.6e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APPPNAGC_01030 3.7e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APPPNAGC_01031 1.7e-151 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APPPNAGC_01032 6.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APPPNAGC_01033 2.3e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
APPPNAGC_01034 3.9e-22 ywmB S TATA-box binding
APPPNAGC_01035 1.3e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APPPNAGC_01036 8.9e-187 spoIID D Stage II sporulation protein D
APPPNAGC_01037 1.9e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
APPPNAGC_01038 7.4e-53 sugE P Multidrug resistance protein
APPPNAGC_01039 4.4e-44 ykkD P Multidrug resistance protein
APPPNAGC_01040 3.6e-45 spoIIID K Stage III sporulation protein D
APPPNAGC_01041 1.6e-180 mbl D Rod shape-determining protein
APPPNAGC_01042 1.1e-136 flhO N flagellar basal body
APPPNAGC_01043 9e-139 flhP N flagellar basal body
APPPNAGC_01044 1.9e-59 epuA S DNA-directed RNA polymerase subunit beta
APPPNAGC_01045 2.6e-267 P Spore gernimation protein GerA
APPPNAGC_01046 7.7e-197 E Spore germination protein
APPPNAGC_01047 3.2e-187 S Spore germination B3/ GerAC like, C-terminal
APPPNAGC_01048 2.5e-107 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APPPNAGC_01049 5.2e-136 estA S Putative esterase
APPPNAGC_01050 4.7e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APPPNAGC_01051 1.9e-289 pip S YhgE Pip N-terminal domain protein
APPPNAGC_01052 1.6e-91 speG_2 2.3.1.57 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APPPNAGC_01053 1.9e-78 yisT S DinB family
APPPNAGC_01054 9.9e-149 Q N-acetyltransferase
APPPNAGC_01055 9e-218 lytE M NlpC/P60 family
APPPNAGC_01056 5.2e-242 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APPPNAGC_01057 1.7e-224
APPPNAGC_01058 1.9e-43 HA62_12640 S GCN5-related N-acetyl-transferase
APPPNAGC_01059 1.3e-160 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
APPPNAGC_01060 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
APPPNAGC_01061 1.9e-223 rodA D Belongs to the SEDS family
APPPNAGC_01062 1.2e-92 yjbB G Transmembrane secretion effector
APPPNAGC_01063 5.6e-74 FG Scavenger mRNA decapping enzyme C-term binding
APPPNAGC_01064 9e-78 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
APPPNAGC_01065 2.2e-50 E LysE type translocator
APPPNAGC_01066 5.9e-80 S Tetratrico peptide repeat
APPPNAGC_01067 5.2e-170 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
APPPNAGC_01068 1.1e-116 ywqC M biosynthesis protein
APPPNAGC_01069 2.2e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
APPPNAGC_01070 3.2e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
APPPNAGC_01071 8.7e-73 S Membrane
APPPNAGC_01072 7.9e-46 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
APPPNAGC_01073 1.2e-198 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APPPNAGC_01074 2.2e-52 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
APPPNAGC_01075 6.9e-254 bglH 3.2.1.86 GT1 G Glycosyl hydrolase family 1
APPPNAGC_01076 6.9e-270 3.2.1.86 GT1 G Glycosyl hydrolase family 1
APPPNAGC_01077 2.8e-148 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_01078 3.5e-183 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
APPPNAGC_01079 8.1e-277 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
APPPNAGC_01080 1.2e-70 yccU S CoA-binding protein
APPPNAGC_01081 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APPPNAGC_01082 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APPPNAGC_01083 8.5e-57 S Uncharacterized protein conserved in bacteria (DUF2200)
APPPNAGC_01084 1.7e-80 dksA T general stress protein
APPPNAGC_01085 5.3e-201 ytvI S sporulation integral membrane protein YtvI
APPPNAGC_01086 7.6e-135 motB N Flagellar motor protein
APPPNAGC_01087 4.1e-139 motA N flagellar motor
APPPNAGC_01088 1.2e-149 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
APPPNAGC_01089 1.9e-105 S Golgi phosphoprotein 3 (GPP34)
APPPNAGC_01090 2.6e-35 K COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit
APPPNAGC_01091 3e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
APPPNAGC_01092 6.2e-80 C HEAT repeats
APPPNAGC_01093 6.6e-45 CP_0264 3.2.2.10 S Belongs to the LOG family
APPPNAGC_01094 6.9e-67 S Bacterial PH domain
APPPNAGC_01095 1e-102 3.4.11.5 I Alpha beta hydrolase
APPPNAGC_01096 1.4e-29 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
APPPNAGC_01097 9.9e-18 GM PFAM NAD-dependent epimerase dehydratase
APPPNAGC_01098 1.3e-82 yfiT S Belongs to the metal hydrolase YfiT family
APPPNAGC_01099 1.1e-56 E LysE type translocator
APPPNAGC_01100 1.4e-99 K AraC family transcriptional regulator
APPPNAGC_01101 4.4e-27 ydjA C Nitroreductase
APPPNAGC_01102 8.5e-46 yfhC C Nitroreductase family
APPPNAGC_01103 1.2e-32 K helix_turn_helix, arabinose operon control protein
APPPNAGC_01104 4e-12
APPPNAGC_01105 3.9e-07 S Family of unknown function (DUF5345)
APPPNAGC_01106 4.2e-92 sigY K Belongs to the sigma-70 factor family. ECF subfamily
APPPNAGC_01107 2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APPPNAGC_01108 2.9e-157 yxlF V ABC transporter, ATP-binding protein
APPPNAGC_01109 1.2e-10 yxlE S Phospholipase_D-nuclease N-terminal
APPPNAGC_01110 2.8e-79 S Domain of unknown function (DUF4188)
APPPNAGC_01111 1.7e-90 padR K Virulence activator alpha C-term
APPPNAGC_01112 2.7e-152 ydeE K AraC family transcriptional regulator
APPPNAGC_01113 8e-74 S Activator of Hsp90 ATPase homolog 1-like protein
APPPNAGC_01114 2.9e-123
APPPNAGC_01115 2.7e-44
APPPNAGC_01116 1.8e-210 blt9 EGP Major facilitator Superfamily
APPPNAGC_01117 1.6e-43
APPPNAGC_01118 3.1e-71
APPPNAGC_01119 3.3e-108 C Zinc-binding dehydrogenase
APPPNAGC_01120 1.3e-276 metP S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APPPNAGC_01122 4.5e-55 yitW S metal-sulfur cluster biosynthetic enzyme
APPPNAGC_01124 3.1e-140 ywfM EG EamA-like transporter family
APPPNAGC_01125 2.7e-126 yeeN K transcriptional regulatory protein
APPPNAGC_01126 9.6e-146 xth 3.1.11.2 L exodeoxyribonuclease III
APPPNAGC_01127 1.5e-242 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
APPPNAGC_01128 1.5e-97 gmhB 3.1.3.82, 3.1.3.83 E D,D-heptose 1,7-bisphosphate phosphatase
APPPNAGC_01129 1.9e-155 asbF 4.2.1.118 G Xylose isomerase-like TIM barrel
APPPNAGC_01130 3.1e-181 asbE IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
APPPNAGC_01131 6.5e-41 asbD IQ Phosphopantetheine attachment site
APPPNAGC_01132 5.6e-220 asbC 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
APPPNAGC_01133 0.0 asbB Q IucA / IucC family
APPPNAGC_01134 0.0 iucA 6.3.2.38 Q Siderophore biosynthesis protein
APPPNAGC_01135 2.6e-58 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
APPPNAGC_01136 2.2e-207 mccB 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
APPPNAGC_01137 3.5e-166 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
APPPNAGC_01138 3.1e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APPPNAGC_01139 1.5e-135 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
APPPNAGC_01140 4.4e-183 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APPPNAGC_01141 1.7e-102 yvdT K Transcriptional regulator
APPPNAGC_01142 1.7e-226 els S Acetyltransferase
APPPNAGC_01143 1.9e-82 lytE2 M COG1388 FOG LysM repeat
APPPNAGC_01144 9.8e-106 yvdD_1 3.2.2.10 S Belongs to the LOG family
APPPNAGC_01145 4.8e-108 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
APPPNAGC_01146 8.2e-140 ykoC P Cobalt transport protein
APPPNAGC_01147 6.3e-271 ykoD 3.6.3.24 P ABC transporter
APPPNAGC_01148 1.2e-101 ykoE S ABC-type cobalt transport system, permease component
APPPNAGC_01149 5.4e-147 ysaA S HAD-hyrolase-like
APPPNAGC_01150 4.4e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
APPPNAGC_01151 2.6e-143 L Transposase
APPPNAGC_01152 5.3e-156 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APPPNAGC_01153 2.9e-159 M 3D domain
APPPNAGC_01154 1.7e-140 M 3D domain
APPPNAGC_01155 1.5e-129 yodH Q Methyltransferase
APPPNAGC_01156 2.5e-264 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APPPNAGC_01157 9.7e-89 S Protein of unknown function (DUF1706)
APPPNAGC_01158 1.1e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APPPNAGC_01159 6.1e-51
APPPNAGC_01160 8e-137 Q Methyltransferase domain
APPPNAGC_01161 8.8e-72 yjcF S Acetyltransferase (GNAT) domain
APPPNAGC_01162 1.4e-37
APPPNAGC_01163 2.7e-235 rtcB 6.5.1.3 S tRNA-splicing ligase RtcB
APPPNAGC_01164 4.2e-81 M Acetyltransferase (GNAT) domain
APPPNAGC_01165 5e-75 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
APPPNAGC_01166 7.2e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APPPNAGC_01167 2.4e-59 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
APPPNAGC_01168 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
APPPNAGC_01169 7.2e-212 tcaB EGP Major facilitator Superfamily
APPPNAGC_01170 1e-117 yugP S Zn-dependent protease
APPPNAGC_01171 3.3e-138 S Sporulation protein YpjB (SpoYpjB)
APPPNAGC_01172 1.9e-107 ypjA S membrane
APPPNAGC_01173 1.7e-145 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
APPPNAGC_01174 7.7e-123 petB C COG1290 Cytochrome b subunit of the bc complex
APPPNAGC_01175 3.8e-90 qcrA C Menaquinol-cytochrome c reductase
APPPNAGC_01176 3.3e-80 ypiF S Protein of unknown function (DUF2487)
APPPNAGC_01177 2.6e-97 ypiB S Belongs to the UPF0302 family
APPPNAGC_01178 5.1e-229 S COG0457 FOG TPR repeat
APPPNAGC_01179 4e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
APPPNAGC_01180 4.4e-200 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
APPPNAGC_01181 9.2e-206 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
APPPNAGC_01182 1.6e-146 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
APPPNAGC_01183 2.8e-224 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
APPPNAGC_01184 9.8e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E phosphoribosylanthranilate isomerase activity
APPPNAGC_01185 9.7e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
APPPNAGC_01186 2.2e-182 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
APPPNAGC_01187 2.6e-280 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APPPNAGC_01188 2.1e-58 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
APPPNAGC_01189 3.3e-192 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
APPPNAGC_01190 3.1e-220 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
APPPNAGC_01191 1.2e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
APPPNAGC_01192 1.4e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
APPPNAGC_01193 6.9e-181 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APPPNAGC_01194 2.9e-159 mqnA 1.21.98.1, 4.2.1.151 S Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
APPPNAGC_01195 5.7e-158 ubiA 2.5.1.39 H UbiA prenyltransferase family
APPPNAGC_01196 3.1e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
APPPNAGC_01197 1.6e-57 hepS 2.5.1.30 H heptaprenyl diphosphate synthase
APPPNAGC_01198 1.6e-35 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
APPPNAGC_01199 5.9e-100 folE 3.5.4.16 H GTP cyclohydrolase
APPPNAGC_01200 4.4e-280 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
APPPNAGC_01201 5.7e-132 yphF
APPPNAGC_01203 4e-38 S Stage VI sporulation protein F
APPPNAGC_01204 4.1e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
APPPNAGC_01205 9e-102 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APPPNAGC_01206 1.2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
APPPNAGC_01207 3e-12 yphA
APPPNAGC_01208 2.4e-201 rpsA 1.17.7.4 J Ribosomal protein S1
APPPNAGC_01209 2.9e-105 plsC 2.3.1.51, 2.7.4.25 I 1-acyl-sn-glycerol-3-phosphate acyltransferase
APPPNAGC_01210 4.1e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
APPPNAGC_01211 8.4e-246 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
APPPNAGC_01212 2.3e-162 sleB 3.5.1.28 M Spore cortex-lytic enzyme
APPPNAGC_01213 0.0 metH 2.1.1.13 E Methionine synthase
APPPNAGC_01214 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
APPPNAGC_01215 3.1e-206 metB 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
APPPNAGC_01216 6.9e-25
APPPNAGC_01217 1.7e-111 prsW S Involved in the degradation of specific anti-sigma factors
APPPNAGC_01218 5.5e-175 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
APPPNAGC_01219 1.6e-180 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
APPPNAGC_01220 1.6e-238 gdhA 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
APPPNAGC_01221 4.8e-177
APPPNAGC_01222 1.4e-267 T PhoQ Sensor
APPPNAGC_01223 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_01224 9.7e-109 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
APPPNAGC_01225 1.7e-165 merR K MerR family transcriptional regulator
APPPNAGC_01226 1.3e-142 ypbG S Calcineurin-like phosphoesterase superfamily domain
APPPNAGC_01227 6.3e-221 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
APPPNAGC_01229 2.5e-176 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APPPNAGC_01230 1.9e-197 cpoA GT4 M Glycosyl transferases group 1
APPPNAGC_01231 2.3e-226 mgs 2.4.1.337 GT4 M Glycosyl Transferase
APPPNAGC_01232 7.2e-37 sinR K Helix-turn-helix XRE-family like proteins
APPPNAGC_01233 1.3e-51 K Helix-turn-helix XRE-family like proteins
APPPNAGC_01234 2.7e-09 ypbF S Protein of unknown function (DUF2663)
APPPNAGC_01236 1e-99 ypbD S metal-dependent membrane protease
APPPNAGC_01237 8.5e-263 recQ 3.6.4.12 L DNA helicase
APPPNAGC_01238 3.9e-174 ypbB 5.1.3.1 S protein conserved in bacteria
APPPNAGC_01239 3.9e-43 fer C Ferredoxin
APPPNAGC_01240 3.9e-298 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APPPNAGC_01241 2.3e-246 nox 1.6.3.4 P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
APPPNAGC_01242 3.4e-135 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
APPPNAGC_01244 1.2e-94 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
APPPNAGC_01245 1.9e-136 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
APPPNAGC_01246 9.2e-187 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPPNAGC_01247 0.0 resE 2.7.13.3 T Histidine kinase
APPPNAGC_01248 9e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_01249 3.5e-219 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
APPPNAGC_01250 1.1e-297 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
APPPNAGC_01251 7.5e-97 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
APPPNAGC_01252 8.3e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APPPNAGC_01253 1.6e-75 spmB S Spore maturation protein
APPPNAGC_01254 9.6e-101 spmA S Spore maturation protein
APPPNAGC_01255 2.4e-209 dacB 3.4.16.4 M Belongs to the peptidase S11 family
APPPNAGC_01256 1.2e-55 spoVAE S stage V sporulation protein
APPPNAGC_01257 5.3e-192 spoVAD I Stage V sporulation protein AD
APPPNAGC_01258 2e-77 spoVAC S stage V sporulation protein AC
APPPNAGC_01259 7.1e-45 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APPPNAGC_01260 1.9e-121 S membrane
APPPNAGC_01261 1.5e-44 S ATP synthase, subunit b
APPPNAGC_01262 7.6e-305 ubiB S ABC1 family
APPPNAGC_01263 9.8e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APPPNAGC_01264 2.7e-168 sodA 1.15.1.1 P Superoxide dismutase
APPPNAGC_01265 3.9e-295 aldA C Belongs to the aldehyde dehydrogenase family
APPPNAGC_01266 1.2e-103 K Uncharacterized protein conserved in bacteria (DUF2087)
APPPNAGC_01267 2e-98 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APPPNAGC_01268 1.4e-125 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APPPNAGC_01269 4.6e-82 ypuF S Domain of unknown function (DUF309)
APPPNAGC_01270 7.9e-82 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
APPPNAGC_01271 2.1e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APPPNAGC_01272 9.4e-110 ribE 2.5.1.9 H Riboflavin synthase
APPPNAGC_01273 4.6e-191 echA9 1.1.1.31, 3.1.2.4, 4.2.1.17 I 3-hydroxyisobutyryl-CoA hydrolase
APPPNAGC_01274 7.9e-274 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APPPNAGC_01275 3.2e-156 hgd 1.1.1.31, 1.1.1.60 I 3-hydroxyisobutyrate dehydrogenase
APPPNAGC_01276 1.1e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
APPPNAGC_01277 1.6e-271 prpD 4.2.1.79 S 2-methylcitrate dehydratase
APPPNAGC_01278 2e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
APPPNAGC_01279 6.6e-196 S Psort location CytoplasmicMembrane, score
APPPNAGC_01281 8.9e-156 ccpC K Transcriptional regulator
APPPNAGC_01282 4.8e-63 tspO T membrane
APPPNAGC_01283 8.9e-80 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APPPNAGC_01284 9.5e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APPPNAGC_01285 6.4e-271 spoVAF EG Stage V sporulation protein AF
APPPNAGC_01286 9.8e-106 spoVAEA S Stage V sporulation protein AE
APPPNAGC_01287 2.5e-56 spoVAEB S Pfam:SpoVA
APPPNAGC_01288 1.1e-181 spoVAD I Stage V sporulation protein AD
APPPNAGC_01289 2.4e-78 S Pfam:SpoVA
APPPNAGC_01290 3.1e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APPPNAGC_01291 9.6e-74 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
APPPNAGC_01292 3.9e-54 spoIIAA T Belongs to the anti-sigma-factor antagonist family
APPPNAGC_01293 1.1e-209 dacF 3.4.16.4 M Belongs to the peptidase S11 family
APPPNAGC_01294 1.1e-138 3.5.1.104 G Polysaccharide deacetylase
APPPNAGC_01295 6.1e-82 yvsG S LexA-binding, inner membrane-associated putative hydrolase
APPPNAGC_01296 1e-52
APPPNAGC_01297 2.1e-20 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
APPPNAGC_01298 3e-238 emrB_1 EGP Major facilitator Superfamily
APPPNAGC_01299 1.2e-119 yocB J translation release factor activity
APPPNAGC_01300 1.8e-69 ohrB O Organic hydroperoxide resistance protein
APPPNAGC_01301 2.4e-229 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
APPPNAGC_01302 2.2e-226 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
APPPNAGC_01303 2.2e-165 xerD L recombinase XerD
APPPNAGC_01304 9.6e-14 S Protein of unknown function (DUF4227)
APPPNAGC_01305 1.2e-85 fur P Belongs to the Fur family
APPPNAGC_01306 1.4e-100 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
APPPNAGC_01307 1.2e-89 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
APPPNAGC_01309 8.2e-82 CO Thioredoxin-like
APPPNAGC_01310 1.7e-140 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
APPPNAGC_01311 1e-146 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01312 7.9e-152 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01313 2.1e-200 T helix_turn_helix, arabinose operon control protein
APPPNAGC_01314 9.3e-280 2.7.13.3 T Cache domain
APPPNAGC_01315 5.3e-229 G Bacterial extracellular solute-binding protein
APPPNAGC_01316 8.1e-210 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
APPPNAGC_01317 1.4e-90 S UPF0316 protein
APPPNAGC_01318 7.3e-78 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
APPPNAGC_01319 1.9e-95 yvbF K Belongs to the GbsR family
APPPNAGC_01320 9.5e-52 ybaZ 2.1.1.63 L Methyltransferase
APPPNAGC_01321 1.8e-81 V COG4767 Glycopeptide antibiotics resistance protein
APPPNAGC_01322 4.5e-185 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
APPPNAGC_01323 0.0 asnO 6.3.5.4 E Asparagine synthase
APPPNAGC_01324 3.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APPPNAGC_01325 2.1e-222 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APPPNAGC_01326 3.7e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APPPNAGC_01327 7.6e-122 P Polycystin cation channel
APPPNAGC_01328 8e-244 lysC 2.7.2.4 E Belongs to the aspartokinase family
APPPNAGC_01330 3.2e-49
APPPNAGC_01331 3.4e-46 tnrA K transcriptional
APPPNAGC_01332 9.1e-139 yibQ S protein conserved in bacteria
APPPNAGC_01333 0.0 apr O Belongs to the peptidase S8 family
APPPNAGC_01334 2.7e-41
APPPNAGC_01335 2e-74 ykuL S CBS domain
APPPNAGC_01336 2.3e-78 3.6.1.55 S Pfam Polyketide cyclase dehydrase and lipid transport
APPPNAGC_01337 7.1e-69 yaaR S protein conserved in bacteria
APPPNAGC_01339 2.1e-95 3.5.1.104 G Polysaccharide deacetylase
APPPNAGC_01340 6.2e-194 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
APPPNAGC_01341 5.1e-69 5.1.99.1 E COG0346 Lactoylglutathione lyase and related lyases
APPPNAGC_01343 4.4e-94 yqjB S protein conserved in bacteria
APPPNAGC_01344 3.9e-168 yqjA S Putative aromatic acid exporter C-terminal domain
APPPNAGC_01345 2.9e-168 pilS 2.7.13.3 F GHKL domain
APPPNAGC_01346 7.3e-122 pbuO_1 S permease
APPPNAGC_01347 2.1e-91 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APPPNAGC_01348 9.8e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
APPPNAGC_01349 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APPPNAGC_01350 7.4e-30 K Cro/C1-type HTH DNA-binding domain
APPPNAGC_01351 2.3e-50 ansR K Helix-turn-helix XRE-family like proteins
APPPNAGC_01352 1.7e-30
APPPNAGC_01353 4.7e-134 yjcH P COG2382 Enterochelin esterase and related enzymes
APPPNAGC_01354 2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
APPPNAGC_01355 3.2e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APPPNAGC_01356 4.6e-186 dglA S Thiamine-binding protein
APPPNAGC_01357 6.7e-96
APPPNAGC_01358 3.4e-141 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APPPNAGC_01359 3e-209 thiO 1.4.3.19 E Glycine oxidase
APPPNAGC_01360 4e-139 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
APPPNAGC_01361 8.8e-27 thiS H ThiS family
APPPNAGC_01362 1e-108 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APPPNAGC_01363 8e-263 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
APPPNAGC_01364 1.1e-173 glcK 2.7.1.2 G Glucokinase
APPPNAGC_01365 5.2e-09 yqgQ S protein conserved in bacteria
APPPNAGC_01366 1.6e-80
APPPNAGC_01367 1e-66 yueI S Protein of unknown function (DUF1694)
APPPNAGC_01368 2.3e-265 spoVAF EG Bacillus/Clostridium GerA spore germination protein
APPPNAGC_01369 2e-291 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
APPPNAGC_01371 2.8e-236 nhaC C Na H antiporter
APPPNAGC_01372 2.1e-185 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
APPPNAGC_01373 1.3e-140 S Integral membrane protein DUF92
APPPNAGC_01374 6.3e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APPPNAGC_01375 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
APPPNAGC_01376 7.2e-124 G PFAM Glycoside hydrolase 15-related
APPPNAGC_01377 6.9e-60
APPPNAGC_01378 8.5e-76 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APPPNAGC_01379 0.0 mrdA 3.4.16.4 M penicillin-binding protein
APPPNAGC_01381 1.3e-232 yqgE EGP Major facilitator superfamily
APPPNAGC_01382 1.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
APPPNAGC_01387 4e-266 nptA P COG1283 Na phosphate symporter
APPPNAGC_01388 2.9e-193 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APPPNAGC_01389 5.6e-113 O NfeD-like C-terminal, partner-binding
APPPNAGC_01390 9.7e-150 ypuA S Secreted protein
APPPNAGC_01391 3.3e-174 EGP Major facilitator Superfamily
APPPNAGC_01392 6.8e-54 fimV NU translation initiation factor activity
APPPNAGC_01393 5.7e-200 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
APPPNAGC_01394 1e-64 yqfX S membrane
APPPNAGC_01395 1.8e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
APPPNAGC_01397 5.3e-36 S Domain of Unknown Function (DUF1540)
APPPNAGC_01400 1.3e-170 L Endonuclease/Exonuclease/phosphatase family
APPPNAGC_01401 1.6e-132 K helix_turn_helix, mercury resistance
APPPNAGC_01402 5.6e-158 aacA-aphD 2.7.1.190 S Protein of unknown function (DUF1679)
APPPNAGC_01403 1.4e-114 O Sap, sulfolipid-1-addressing protein
APPPNAGC_01404 1.8e-69
APPPNAGC_01405 3e-142 K MerR family transcriptional regulator
APPPNAGC_01406 7.4e-150 K Acetyltransferase (GNAT) family
APPPNAGC_01407 2.3e-191 MA20_01110 4.2.1.81 M Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
APPPNAGC_01408 2.7e-133 KT PFAM sigma-54 factor interaction domain-containing protein
APPPNAGC_01409 3.2e-191 EGP MFS/sugar transport protein
APPPNAGC_01410 7.5e-124 S Protein of unknown function (DUF2812)
APPPNAGC_01411 4.5e-49 padR K Transcriptional regulator PadR-like family
APPPNAGC_01412 6.7e-56 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
APPPNAGC_01413 2e-25 K Helix-turn-helix domain
APPPNAGC_01414 1.7e-73
APPPNAGC_01415 1.7e-80 rimL 2.3.1.128 J Acetyltransferase (GNAT) domain
APPPNAGC_01417 7.9e-191 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
APPPNAGC_01418 2.2e-105 E GDSL-like Lipase/Acylhydrolase
APPPNAGC_01419 3.8e-290 E COG0747 ABC-type dipeptide transport system, periplasmic component
APPPNAGC_01422 1.2e-07
APPPNAGC_01423 1.5e-07
APPPNAGC_01428 5.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
APPPNAGC_01429 2.1e-120 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
APPPNAGC_01430 5.7e-144 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APPPNAGC_01431 5.2e-218 ybbR S protein conserved in bacteria
APPPNAGC_01432 1.8e-248 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APPPNAGC_01434 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APPPNAGC_01435 1.2e-34
APPPNAGC_01436 5.1e-210 L ATP-dependent endonuclease of the OLD
APPPNAGC_01437 5.7e-114 3.6.4.12 L ATP-dependent DNA helicase activity
APPPNAGC_01438 6.2e-104 2.7.1.163 S Aminoglycoside phosphotransferase
APPPNAGC_01439 1.1e-25 abrB K Transcriptional regulator, AbrB family
APPPNAGC_01440 1e-89 yfiR K Bacterial regulatory proteins, tetR family
APPPNAGC_01441 1.5e-87 J Acetyltransferase (GNAT) domain
APPPNAGC_01442 3.2e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APPPNAGC_01443 3.3e-58 3.1.3.73 G phosphoglycerate mutase
APPPNAGC_01447 1.9e-69 K SpoVT / AbrB like domain
APPPNAGC_01448 8.4e-213 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
APPPNAGC_01449 1.1e-141 V ABC transporter, ATP-binding protein
APPPNAGC_01450 0.0 V FtsX-like permease family
APPPNAGC_01451 9.4e-121 T Transcriptional regulatory protein, C terminal
APPPNAGC_01452 6.8e-187 T Histidine kinase-like ATPases
APPPNAGC_01453 5.2e-108 K Bacterial regulatory proteins, tetR family
APPPNAGC_01454 1.1e-224 mefE EGP Transmembrane secretion effector
APPPNAGC_01455 1.7e-253 V FtsX-like permease family
APPPNAGC_01456 7.9e-107 V FtsX-like permease family
APPPNAGC_01457 2.1e-132 V ABC transporter
APPPNAGC_01460 2.7e-67 V HNH endonuclease
APPPNAGC_01461 3.8e-24 S CAAX protease self-immunity
APPPNAGC_01462 8.5e-55 ytrA K GntR family transcriptional regulator
APPPNAGC_01463 1.8e-156 V ABC transporter, ATP-binding protein
APPPNAGC_01464 1.4e-91 S ABC-2 family transporter protein
APPPNAGC_01465 5.5e-56 gluQ 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APPPNAGC_01466 1.9e-153 bla 3.5.2.6 V beta-lactamase
APPPNAGC_01467 4e-304 blaR 3.5.2.6 KTV BlaR1 peptidase M56
APPPNAGC_01468 6.6e-63 blaI K Penicillinase repressor
APPPNAGC_01469 1.4e-141 aadD H KNTase C-terminal domain
APPPNAGC_01470 8.4e-63 cadC K transcriptional
APPPNAGC_01471 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
APPPNAGC_01472 1.2e-188 P Oxidoreductase
APPPNAGC_01473 5.1e-82 2.3.1.128 J Acetyltransferase (GNAT) domain
APPPNAGC_01474 5.7e-78
APPPNAGC_01475 1.5e-135 Q ubiE/COQ5 methyltransferase family
APPPNAGC_01476 5.7e-183 trpS 6.1.1.2 J Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
APPPNAGC_01477 1.1e-113 Q SAM-dependent methyltransferase
APPPNAGC_01478 4e-140 ydfC EG EamA-like transporter family
APPPNAGC_01479 3.3e-136 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APPPNAGC_01480 6.8e-110 panZ K Acetyltransferase (GNAT) domain
APPPNAGC_01481 1.1e-62
APPPNAGC_01482 1.7e-70 S Protein of unknown function (DUF2512)
APPPNAGC_01483 2.9e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
APPPNAGC_01484 8.5e-84 2.3.1.128 J Acetyltransferase (GNAT) domain
APPPNAGC_01485 1.1e-297 siaT_1 S Tripartite ATP-independent periplasmic transporter, DctM component
APPPNAGC_01486 1.3e-51 S Domain of unknown function (DUF1850)
APPPNAGC_01487 8.9e-120 thyA S NMT1-like family
APPPNAGC_01488 1.1e-302 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
APPPNAGC_01489 8.1e-117 ktrA P COG0569 K transport systems, NAD-binding component
APPPNAGC_01490 3.6e-165 I alpha/beta hydrolase fold
APPPNAGC_01491 4.2e-212 F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APPPNAGC_01492 5.5e-92 adk 2.7.4.3 F topology modulation protein
APPPNAGC_01495 2.1e-85 ftnA 1.16.3.2 P Iron-storage protein
APPPNAGC_01496 2.7e-157 yueF S transporter activity
APPPNAGC_01497 2.2e-274 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APPPNAGC_01498 7e-91 S Peptidase propeptide and YPEB domain
APPPNAGC_01499 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
APPPNAGC_01500 8.2e-206 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
APPPNAGC_01501 1.4e-81 G Tripartite ATP-independent periplasmic transporters, DctQ component
APPPNAGC_01502 7.6e-183 G Bacterial extracellular solute-binding protein, family 7
APPPNAGC_01503 8.7e-168 K helix_turn _helix lactose operon repressor
APPPNAGC_01504 3.5e-135 K helix_turn_helix, mercury resistance
APPPNAGC_01505 0.0 msbA2 3.6.3.44 V ABC transporter
APPPNAGC_01506 8.2e-146 ybbH_2 K Transcriptional regulator
APPPNAGC_01507 9.1e-181 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
APPPNAGC_01508 1.4e-237 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
APPPNAGC_01509 1.5e-167 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
APPPNAGC_01511 2.9e-285 K Propionate catabolism activator
APPPNAGC_01512 1.2e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APPPNAGC_01513 7e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APPPNAGC_01514 5.7e-189 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
APPPNAGC_01515 6.4e-62 purR15 K Bacterial regulatory proteins, lacI family
APPPNAGC_01516 2.1e-100 purR15 K Bacterial regulatory proteins, lacI family
APPPNAGC_01517 3.2e-272 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APPPNAGC_01518 2.8e-149 ypbG 2.7.1.2 GK ROK family
APPPNAGC_01519 1.8e-138 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01520 1e-162 P COG0395 ABC-type sugar transport system, permease component
APPPNAGC_01521 1.2e-99 G Bacterial extracellular solute-binding protein
APPPNAGC_01522 1.8e-105 G Bacterial extracellular solute-binding protein
APPPNAGC_01523 1.2e-140 manA3 3.2.1.78 GH26 G Endoglucanase
APPPNAGC_01524 3.5e-36 S Protein of unknown function (DUF2642)
APPPNAGC_01525 4.2e-12
APPPNAGC_01526 1.5e-97 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
APPPNAGC_01527 4.2e-138 1.6.5.5 C alcohol dehydrogenase
APPPNAGC_01528 7.1e-77 K Transcriptional regulator
APPPNAGC_01529 1.5e-52 fdx5 C 2Fe-2S iron-sulfur cluster binding domain
APPPNAGC_01530 5.9e-20
APPPNAGC_01531 1.6e-297 KT Transcriptional regulator
APPPNAGC_01532 1.1e-50 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
APPPNAGC_01533 1.7e-76 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
APPPNAGC_01534 8.9e-232 EG COG2610 H gluconate symporter and related permeases
APPPNAGC_01535 8.7e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
APPPNAGC_01536 3.1e-196 eutG C alcohol dehydrogenase
APPPNAGC_01537 6.1e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APPPNAGC_01538 3.8e-260 EG Bacillus/Clostridium GerA spore germination protein
APPPNAGC_01539 8.1e-51
APPPNAGC_01540 1e-87 ectA 2.3.1.178 K L-2,4-diaminobutyric acid acetyltransferase
APPPNAGC_01541 2.3e-245 ectB 2.6.1.76 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APPPNAGC_01542 9.5e-76 ectC 4.2.1.108 S Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
APPPNAGC_01543 2.3e-248 G Glycerol-3-phosphate ABC transporter substrate-binding protein
APPPNAGC_01544 1.2e-146 G Xylose isomerase-like TIM barrel
APPPNAGC_01545 6.4e-165 G ABC transporter (permease)
APPPNAGC_01546 1.6e-146 ugpE P PFAM binding-protein-dependent transport systems inner membrane component
APPPNAGC_01547 1.2e-194 3.6.3.20 P Belongs to the ABC transporter superfamily
APPPNAGC_01549 4e-236 KLT Protein kinase domain
APPPNAGC_01552 3.9e-76 H Tellurite resistance protein TehB
APPPNAGC_01553 5e-50 S ABC-2 family transporter protein
APPPNAGC_01555 1.1e-310 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APPPNAGC_01556 1.3e-265 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
APPPNAGC_01557 1.3e-199 vraB 2.3.1.9 I Belongs to the thiolase family
APPPNAGC_01558 1.5e-27 S response regulator aspartate phosphatase
APPPNAGC_01560 1e-59
APPPNAGC_01561 3.2e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APPPNAGC_01562 1.4e-187 araC2 K Arabinose-binding domain of AraC transcription regulator, N-term
APPPNAGC_01564 4.4e-74 nsrR K Transcriptional regulator
APPPNAGC_01565 9.8e-233 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APPPNAGC_01566 0.0 glpQ1 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
APPPNAGC_01567 5.1e-196 ugpC 3.6.3.20 P Belongs to the ABC transporter superfamily
APPPNAGC_01568 8.1e-163 ugpA G ABC transporter (permease)
APPPNAGC_01569 1.7e-140 ugpE P Glycerol-3-phosphate ABC transporter permease
APPPNAGC_01570 1.4e-229 ugpB G Glycerol-3-phosphate ABC transporter substrate-binding protein
APPPNAGC_01571 5.6e-138 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APPPNAGC_01572 1.4e-207 yceL EGP Major Facilitator Superfamily
APPPNAGC_01573 5.4e-308 G Bacterial extracellular solute-binding protein
APPPNAGC_01574 8.2e-148 3.1.3.41 G Haloacid dehalogenase-like hydrolase
APPPNAGC_01575 1.6e-91 K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
APPPNAGC_01576 1.8e-173 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01577 2.8e-157 G COG0395 ABC-type sugar transport system, permease component
APPPNAGC_01578 4e-122 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APPPNAGC_01579 9.1e-175 G Xylose isomerase-like TIM barrel
APPPNAGC_01580 1.7e-193 S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_01581 1.3e-99 ykoP G polysaccharide deacetylase
APPPNAGC_01582 1.8e-172
APPPNAGC_01583 2.8e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_01584 3.2e-147 K helix_turn_helix, arabinose operon control protein
APPPNAGC_01585 7.5e-67 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APPPNAGC_01586 5.1e-170 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
APPPNAGC_01587 9.4e-256 yhdG E amino acid
APPPNAGC_01588 4.2e-178 K AraC-like ligand binding domain
APPPNAGC_01589 0.0 rhaA 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
APPPNAGC_01590 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
APPPNAGC_01591 4.8e-51 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
APPPNAGC_01592 9.5e-223 iolF EGP Major facilitator Superfamily
APPPNAGC_01593 3.6e-146 K AraC-like ligand binding domain
APPPNAGC_01594 7.4e-230 MA20_16885 S Oxidoreductase family, NAD-binding Rossmann fold
APPPNAGC_01595 4.2e-217 MA20_16880 EM Protein of unknown function (DUF993)
APPPNAGC_01596 7.6e-157 MA20_16875 G Xylose isomerase-like TIM barrel
APPPNAGC_01597 1.1e-209 S Oxidoreductase family, NAD-binding Rossmann fold
APPPNAGC_01598 0.0 2.7.13.3 T Histidine kinase
APPPNAGC_01599 4.1e-198 T helix_turn_helix, arabinose operon control protein
APPPNAGC_01600 1.7e-246 G Bacterial extracellular solute-binding protein
APPPNAGC_01601 2.5e-175 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01602 1.6e-154 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_01603 3.9e-193 I Acyltransferase family
APPPNAGC_01604 1.2e-231 arlS T His Kinase A (phosphoacceptor) domain
APPPNAGC_01605 1.3e-117 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_01606 4e-127 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
APPPNAGC_01607 0.0 E cell wall organization
APPPNAGC_01608 1.4e-237 G Bacterial extracellular solute-binding protein
APPPNAGC_01609 9.9e-153 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01610 2.1e-157 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_01611 5.1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
APPPNAGC_01612 5.9e-241 G Bacterial extracellular solute-binding protein
APPPNAGC_01613 6.7e-159 amyD G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01614 1.2e-152 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_01615 3.7e-103 S Protein of unknown function, DUF624
APPPNAGC_01616 1e-170 M1-640 K Transcriptional regulator
APPPNAGC_01617 1.2e-163 rhaR1 K AraC-like ligand binding domain
APPPNAGC_01618 1.9e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
APPPNAGC_01619 9.2e-212 egsA 1.1.1.261 C Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
APPPNAGC_01620 2.3e-133 araD 4.1.2.17, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
APPPNAGC_01621 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
APPPNAGC_01622 3.6e-282 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
APPPNAGC_01623 3.8e-196 chvE G ABC transporter
APPPNAGC_01624 1.5e-278 araG 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
APPPNAGC_01625 2e-195 gguB G Belongs to the binding-protein-dependent transport system permease family
APPPNAGC_01626 3.5e-296 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
APPPNAGC_01627 2.6e-51 V ATPases associated with a variety of cellular activities
APPPNAGC_01628 5.6e-23
APPPNAGC_01629 2.7e-77 S Putative small multi-drug export protein
APPPNAGC_01630 2.8e-107 V Transport permease protein
APPPNAGC_01631 8.5e-179 KTV LytTr DNA-binding domain
APPPNAGC_01632 3.8e-48 sugE P Small Multidrug Resistance protein
APPPNAGC_01633 3.2e-59 sugE P Small Multidrug Resistance protein
APPPNAGC_01634 1.9e-98 yvdT K Transcriptional regulator
APPPNAGC_01635 2.8e-239 EGP Major Facilitator Superfamily
APPPNAGC_01636 5.9e-135 iolR K COG1349 Transcriptional regulators of sugar metabolism
APPPNAGC_01637 5.6e-275 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APPPNAGC_01638 1.6e-146 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
APPPNAGC_01639 3.7e-174 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
APPPNAGC_01640 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
APPPNAGC_01641 1.9e-169 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
APPPNAGC_01642 6.2e-188 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
APPPNAGC_01643 8.2e-98 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
APPPNAGC_01644 2.9e-154 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
APPPNAGC_01645 3e-171 yisS 1.1.1.370 S Oxidoreductase family, NAD-binding Rossmann fold
APPPNAGC_01646 6.2e-264 yidK S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APPPNAGC_01647 1.9e-137 iolH G Xylose isomerase-like TIM barrel
APPPNAGC_01648 1.7e-148 iolT EGP Major facilitator Superfamily
APPPNAGC_01649 1.2e-244 metY 2.5.1.49 E O-acetylhomoserine
APPPNAGC_01650 3.9e-62 S Putative zinc- or iron-chelating domain
APPPNAGC_01651 2.4e-142 bxlB G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01652 4.3e-164 bxlC G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01653 9.6e-247 bxlD G Bacterial extracellular solute-binding protein
APPPNAGC_01655 1.9e-158 K AraC-like ligand binding domain
APPPNAGC_01656 1.1e-186 yjjN E Alcohol dehydrogenase GroES-like domain
APPPNAGC_01657 6e-188 dctP G Bacterial extracellular solute-binding protein, family 7
APPPNAGC_01658 2.3e-81 G Tripartite ATP-independent periplasmic transporters, DctQ component
APPPNAGC_01659 4.7e-222 G Tripartite ATP-independent periplasmic transporter, DctM component
APPPNAGC_01660 6.4e-287 uxaA 4.2.1.7 G Altronate
APPPNAGC_01661 2e-288 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
APPPNAGC_01662 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 K transcriptional regulator, MtlR
APPPNAGC_01663 8.7e-159 4.1.2.13 G Fructose-bisphosphate aldolase class-II
APPPNAGC_01664 4.4e-77 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APPPNAGC_01665 1.1e-47 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
APPPNAGC_01666 6.5e-164 fruA2 G Phosphotransferase System
APPPNAGC_01667 9.2e-92 5.3.1.15 S Cupin 2, conserved barrel domain protein
APPPNAGC_01669 2.4e-267 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APPPNAGC_01670 3e-159 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
APPPNAGC_01671 8.5e-102 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
APPPNAGC_01672 5.5e-253 KT Transcriptional regulator
APPPNAGC_01673 3.7e-233 E Acyclic terpene utilisation family protein AtuA
APPPNAGC_01674 1.2e-49
APPPNAGC_01675 3.6e-217 C Citrate transporter
APPPNAGC_01676 5.6e-242 NT chemotaxis protein
APPPNAGC_01677 1.5e-237 V MatE
APPPNAGC_01678 1.1e-38
APPPNAGC_01679 2.4e-98 S Tetratricopeptide repeat
APPPNAGC_01680 2.7e-67 3.6.1.55 F NUDIX domain
APPPNAGC_01681 2.1e-63
APPPNAGC_01682 9.4e-53
APPPNAGC_01683 7.2e-189 uxuA 4.2.1.8 G mannonate dehydratase activity
APPPNAGC_01684 3.2e-189 S Tripartite tricarboxylate transporter family receptor
APPPNAGC_01685 1.1e-262 S Tripartite tricarboxylate transporter TctA family
APPPNAGC_01686 7e-79 S Tripartite tricarboxylate transporter TctB family
APPPNAGC_01687 8.1e-255 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APPPNAGC_01688 8e-171 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
APPPNAGC_01689 1.8e-119 ycbG K FCD
APPPNAGC_01690 1.1e-113 K FCD
APPPNAGC_01691 2.5e-204 yeaN P COG2807 Cyanate permease
APPPNAGC_01692 4.4e-62 cdd_2 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
APPPNAGC_01693 1.3e-73 K Transcriptional regulator
APPPNAGC_01694 5.6e-147 3.4.16.4 V Beta-lactamase
APPPNAGC_01695 4.3e-112 yybG S Pentapeptide repeat-containing protein
APPPNAGC_01696 4.2e-44 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
APPPNAGC_01697 6.9e-237 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APPPNAGC_01698 1.4e-48 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
APPPNAGC_01699 9.9e-274 gmuD 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APPPNAGC_01700 0.0 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
APPPNAGC_01701 1.1e-59 K TetR family transcriptional regulator
APPPNAGC_01702 1.1e-106 IQ Enoyl-(Acyl carrier protein) reductase
APPPNAGC_01703 2.2e-79 K Bacterial transcription activator, effector binding domain
APPPNAGC_01704 3e-84
APPPNAGC_01705 1.1e-211 ydhP 3.2.1.21, 3.2.1.86 GT1 G Glycosyl hydrolase family 1
APPPNAGC_01706 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
APPPNAGC_01707 1.1e-190 3.2.1.96 G Glycosyl hydrolase family 85
APPPNAGC_01708 2.8e-256 mngB 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G Alpha mannosidase, middle domain
APPPNAGC_01709 2.7e-188 S Glycosyl hydrolase
APPPNAGC_01710 5.5e-27 S Protein of unknown function, DUF624
APPPNAGC_01711 2.2e-121 2.7.13.3 T Histidine kinase
APPPNAGC_01712 3e-103 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
APPPNAGC_01713 5.3e-130 ypdA G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01714 3.1e-133 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01715 7.8e-205 G ABC transporter substrate-binding protein
APPPNAGC_01716 4e-71 GK ROK family
APPPNAGC_01717 1.7e-94 yocH 3.5.1.28 M 3D domain
APPPNAGC_01718 1.1e-205 2.3.1.157, 2.7.7.23 JM Bacterial transferase hexapeptide (six repeats)
APPPNAGC_01719 1.3e-125 K transcriptional
APPPNAGC_01720 1.7e-139 S carbohydrate derivative metabolic process
APPPNAGC_01721 1.9e-84 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_01722 2.4e-240 ykoH T Histidine kinase
APPPNAGC_01723 4e-117 ykoI S Peptidase propeptide and YPEB domain
APPPNAGC_01724 1.4e-82 ykoJ S Peptidase propeptide and YPEB domain
APPPNAGC_01725 8.8e-122 glxK 2.7.1.165 G Glycerate kinase family
APPPNAGC_01726 3.9e-108 P Sodium:sulfate symporter transmembrane region
APPPNAGC_01728 1.7e-235 I radical SAM domain protein
APPPNAGC_01729 1.1e-283 H Involved in the biosynthesis of porphyrin-containing compound
APPPNAGC_01730 8e-11
APPPNAGC_01731 1.3e-134 yafE Q methyltransferase
APPPNAGC_01732 1.8e-14 1.2.7.12 S Uncharacterised protein family UPF0066
APPPNAGC_01733 4.4e-88 1.2.7.12 S Uncharacterised protein family UPF0066
APPPNAGC_01734 2.3e-221 EGP Major facilitator Superfamily
APPPNAGC_01735 3.2e-95 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APPPNAGC_01736 3.7e-168 wbpP 5.1.3.2, 5.1.3.7 M GDP-mannose 4,6 dehydratase
APPPNAGC_01737 1.7e-126 M Glycosyl transferases group 1
APPPNAGC_01738 3.2e-102
APPPNAGC_01739 8.3e-104 GT2,GT4 M transferase activity, transferring glycosyl groups
APPPNAGC_01740 3.9e-122 M transferase activity, transferring glycosyl groups
APPPNAGC_01741 2.8e-112 M Glycosyl transferase family 2
APPPNAGC_01742 1e-235 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APPPNAGC_01743 4.7e-66 VPA1573 J acetyltransferase
APPPNAGC_01744 8.6e-224 M Glycosyltransferase like family 2
APPPNAGC_01745 3.9e-36 S Protein of unknown function (DUF2642)
APPPNAGC_01746 9.3e-24
APPPNAGC_01747 1e-240 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
APPPNAGC_01748 1.1e-104 ycsK E anatomical structure formation involved in morphogenesis
APPPNAGC_01749 6.8e-120 K helix_turn_helix isocitrate lyase regulation
APPPNAGC_01750 1e-165 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
APPPNAGC_01751 4.7e-104 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
APPPNAGC_01752 3.7e-226 dgoD 4.2.1.6 M Belongs to the mandelate racemase muconate lactonizing enzyme family
APPPNAGC_01753 4.7e-196 gntU EG COG2610 H gluconate symporter and related permeases
APPPNAGC_01754 5.4e-155 S Metallo-beta-lactamase superfamily
APPPNAGC_01755 1.6e-87 S Predicted membrane protein (DUF2243)
APPPNAGC_01756 1.1e-118 S Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
APPPNAGC_01757 1.3e-230 T COG0642 Signal transduction histidine kinase
APPPNAGC_01758 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_01759 1.7e-174 4.2.1.103 K DJ-1/PfpI family
APPPNAGC_01760 3.2e-110 S Predicted membrane protein (DUF2306)
APPPNAGC_01761 1.8e-201 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
APPPNAGC_01762 1.1e-69 S VanZ like family
APPPNAGC_01763 3.7e-108 wrbA 1.6.5.2 S Belongs to the WrbA family
APPPNAGC_01765 3.5e-82 2.3.1.128 K Acetyltransferase (GNAT) family
APPPNAGC_01766 5.2e-131 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
APPPNAGC_01767 0.0 V SNF2 family N-terminal domain
APPPNAGC_01768 3.5e-11 S Domain of unknown function (DUF5082)
APPPNAGC_01769 3.3e-08 S Family of unknown function (DUF5344)
APPPNAGC_01770 2.1e-248 S LXG domain of WXG superfamily
APPPNAGC_01771 1.8e-102
APPPNAGC_01772 9e-102
APPPNAGC_01773 2.8e-148
APPPNAGC_01774 3.2e-281 E Sodium:solute symporter family
APPPNAGC_01775 3.5e-23
APPPNAGC_01776 7.6e-222 2.8.3.16, 2.8.3.20 C acyl-CoA transferases carnitine dehydratase
APPPNAGC_01777 4.5e-112 K FCD domain
APPPNAGC_01778 9.8e-158 4.1.3.4, 4.1.3.46 E Hydroxymethylglutaryl-CoA lyase
APPPNAGC_01779 1.3e-87 L COG2801 Transposase and inactivated derivatives
APPPNAGC_01780 1.1e-71 L transposase activity
APPPNAGC_01781 3.6e-101 gntR K RpiR family transcriptional regulator
APPPNAGC_01782 2.5e-181 EG COG2610 H gluconate symporter and related permeases
APPPNAGC_01783 2.4e-127 garR 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
APPPNAGC_01784 9.4e-187 S Putative nucleotide-binding of sugar-metabolising enzyme
APPPNAGC_01785 3.4e-222 abgB 3.5.1.47 S amidohydrolase
APPPNAGC_01786 1e-156 metQ M Belongs to the nlpA lipoprotein family
APPPNAGC_01787 8.1e-112 P COG2011 ABC-type metal ion transport system, permease component
APPPNAGC_01788 1.1e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APPPNAGC_01789 1e-165 K helix_turn_helix, arabinose operon control protein
APPPNAGC_01790 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
APPPNAGC_01791 0.0 aguA 3.2.1.139 G Belongs to the glycosyl hydrolase 67 family
APPPNAGC_01792 4.3e-175 lplB G Binding-protein-dependent transport system inner membrane component
APPPNAGC_01793 2.6e-155 lplC G COG0395 ABC-type sugar transport system, permease component
APPPNAGC_01794 5.3e-303 G Bacterial extracellular solute-binding protein
APPPNAGC_01795 4.6e-102 S Protein of unknown function, DUF624
APPPNAGC_01796 2.1e-194 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
APPPNAGC_01797 1e-25 D nuclear chromosome segregation
APPPNAGC_01799 2.1e-216 hutI Q COG1228 Imidazolonepropionase and related amidohydrolases
APPPNAGC_01800 9.1e-198 Q COG1228 Imidazolonepropionase and related amidohydrolases
APPPNAGC_01801 4.4e-302 E COG0747 ABC-type dipeptide transport system, periplasmic component
APPPNAGC_01802 6e-169 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_01803 8e-152 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_01804 1.4e-189 oppD P Belongs to the ABC transporter superfamily
APPPNAGC_01805 8.3e-190 ddpF E Belongs to the ABC transporter superfamily
APPPNAGC_01806 2.6e-172 S Protein of unknown function (DUF1177)
APPPNAGC_01807 2.6e-241 3.5.1.18 E Acetylornithine deacetylase
APPPNAGC_01808 8.1e-137 K Transcriptional regulator
APPPNAGC_01809 1.3e-259 xylA 5.3.1.5 G Belongs to the xylose isomerase family
APPPNAGC_01810 1.4e-278 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G xylulose kinase
APPPNAGC_01811 1.4e-195 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
APPPNAGC_01812 1.4e-209 xylR GK ROK family
APPPNAGC_01813 4.8e-122 MA20_14010 S Trehalose utilisation
APPPNAGC_01814 2.2e-221 yrbE S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_01815 1.7e-274 KT PucR C-terminal helix-turn-helix domain
APPPNAGC_01816 2.3e-108 hyuE 5.1.99.3 E Asp/Glu/Hydantoin racemase
APPPNAGC_01817 6.3e-285 S OPT oligopeptide transporter protein
APPPNAGC_01818 1e-185 S Protein of unknown function (DUF917)
APPPNAGC_01819 1.5e-161 S Protein of unknown function (DUF1177)
APPPNAGC_01820 1.6e-112 aroM E AroM protein
APPPNAGC_01821 1e-173 E Thermophilic metalloprotease (M29)
APPPNAGC_01822 1.5e-206 EGP Major facilitator Superfamily
APPPNAGC_01823 3.1e-30 dmpI 5.3.2.6 S Tautomerase enzyme
APPPNAGC_01824 5.9e-203 chrA P chromate transporter, chromate ion transporter
APPPNAGC_01825 6.7e-44 M1-594 S Thiamine-binding protein
APPPNAGC_01826 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APPPNAGC_01827 1.7e-238
APPPNAGC_01829 2.4e-232 gntT EG gluconate transmembrane transporter activity
APPPNAGC_01830 5.9e-139 2.7.1.196, 2.7.1.205 K sequence-specific DNA binding
APPPNAGC_01831 2e-120 S protein conserved in bacteria
APPPNAGC_01832 1e-75
APPPNAGC_01833 2e-92 K Transcriptional regulator PadR-like family
APPPNAGC_01834 2.4e-161 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
APPPNAGC_01835 1.8e-27
APPPNAGC_01836 4e-119 K FCD
APPPNAGC_01837 1.6e-221 S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_01838 2.2e-199 S oxidoreductase
APPPNAGC_01839 1.8e-176 G Bacterial extracellular solute-binding protein, family 7
APPPNAGC_01840 4.9e-74 G Tripartite ATP-independent periplasmic transporters, DctQ component
APPPNAGC_01841 7.5e-207 G COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
APPPNAGC_01842 2.8e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
APPPNAGC_01843 8.1e-218 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
APPPNAGC_01844 8.7e-185 cysP P phosphate transporter
APPPNAGC_01845 1.4e-110 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
APPPNAGC_01846 6.6e-265 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
APPPNAGC_01847 3.7e-137 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 C CbiX
APPPNAGC_01848 6.3e-103 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
APPPNAGC_01849 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
APPPNAGC_01850 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
APPPNAGC_01851 2.3e-21
APPPNAGC_01852 3.2e-153 V ABC transporter
APPPNAGC_01853 2.2e-58 gntR1 K GntR family transcriptional regulator
APPPNAGC_01854 2.4e-209 mii 5.3.3.6 S PrpF protein
APPPNAGC_01855 1.4e-64 S Tripartite tricarboxylate transporter TctB family
APPPNAGC_01856 1.6e-261 S Tripartite tricarboxylate transporter TctA family
APPPNAGC_01857 5.3e-209 S Tripartite tricarboxylate transporter family receptor
APPPNAGC_01858 1.3e-167 yraN K Transcriptional regulator
APPPNAGC_01859 3.6e-191 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
APPPNAGC_01860 3.5e-285 C COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
APPPNAGC_01861 6.2e-188 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
APPPNAGC_01862 1.7e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
APPPNAGC_01863 9.9e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APPPNAGC_01864 1.3e-102 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
APPPNAGC_01865 2.7e-103 tetR K Bacterial regulatory proteins, tetR family
APPPNAGC_01866 2.1e-179 ybcL EGP Major facilitator Superfamily
APPPNAGC_01868 2.5e-227 cstA T Carbon starvation protein
APPPNAGC_01869 2.3e-198 ycgA S C4-dicarboxylate anaerobic carrier
APPPNAGC_01870 3e-84 K Helix-turn-helix domain, rpiR family
APPPNAGC_01871 4.6e-128 MA20_32325 3.4.17.11 E Peptidase dimerisation domain
APPPNAGC_01872 1.4e-157 arsB P Arsenic resistance protein
APPPNAGC_01873 1.9e-90
APPPNAGC_01874 8.2e-123 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
APPPNAGC_01875 4.1e-44 2.7.1.196, 2.7.1.205 G phosphotransferase system
APPPNAGC_01876 4.3e-50 celC 2.7.1.196, 2.7.1.205 G phosphotransferase system
APPPNAGC_01877 1.7e-238 ywbA G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APPPNAGC_01878 1.4e-248 celF 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APPPNAGC_01879 1.2e-132 chbG 2.7.1.196, 2.7.1.205, 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
APPPNAGC_01880 8.9e-136 K UTRA
APPPNAGC_01881 0.0 chiA 3.2.1.14 GH18 G Glycoside Hydrolase Family 18
APPPNAGC_01882 2.6e-38 S Family of unknown function (DUF5391)
APPPNAGC_01883 6.2e-47 S Protein of unknown function (DUF1093)
APPPNAGC_01884 3.5e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
APPPNAGC_01885 1.6e-202 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APPPNAGC_01886 5.2e-245 kynU 3.7.1.3 E Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
APPPNAGC_01887 3e-116 kynB 3.5.1.9 S Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
APPPNAGC_01888 3.7e-154 kynA 1.13.11.11 E Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
APPPNAGC_01889 3.5e-200 E Spore germination protein
APPPNAGC_01891 7.3e-209 gerKC S spore germination
APPPNAGC_01892 3.2e-270 gerKA EG Spore germination protein
APPPNAGC_01893 5.4e-133 ygbI K DeoR C terminal sensor domain
APPPNAGC_01894 1.4e-234 2.7.1.219, 2.7.1.220 S Putative nucleotide-binding of sugar-metabolising enzyme
APPPNAGC_01895 1.2e-185 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 H Belongs to the PdxA family
APPPNAGC_01896 4.6e-215 gntP EG GntP family permease
APPPNAGC_01897 4.8e-151 araQ5 P PFAM binding-protein-dependent transport systems inner membrane component
APPPNAGC_01898 9.6e-156 cebF P PFAM binding-protein-dependent transport systems inner membrane component
APPPNAGC_01899 6.6e-229 lacE3 G PFAM extracellular solute-binding protein family 1
APPPNAGC_01902 8.6e-248 argE 3.5.1.16 E Acetylornithine deacetylase
APPPNAGC_01903 7e-124 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APPPNAGC_01904 1.6e-45
APPPNAGC_01905 5e-176 glpX 2.2.1.1, 3.1.3.11, 3.1.3.37 G Bacterial fructose-1,6-bisphosphatase, glpX-encoded
APPPNAGC_01906 2.6e-112 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 S Dak2
APPPNAGC_01907 6.7e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
APPPNAGC_01908 9.4e-80 rpiB 5.3.1.34, 5.3.1.6 G Ribose/Galactose Isomerase
APPPNAGC_01909 4.4e-133 K DeoR C terminal sensor domain
APPPNAGC_01910 6.1e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_01911 7.9e-210 1.1.1.14 E Dehydrogenase
APPPNAGC_01912 2.7e-238 yoaB EGP Major facilitator Superfamily
APPPNAGC_01913 1.6e-54 S DUF35 OB-fold domain, acyl-CoA-associated
APPPNAGC_01914 1.1e-201 2.3.1.16, 2.3.1.9 I Thiolase, C-terminal domain
APPPNAGC_01915 8e-282 MA20_41335 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APPPNAGC_01916 1.3e-92 S DNA-binding protein with PD1-like DNA-binding motif
APPPNAGC_01917 1.9e-138 IQ Enoyl-(Acyl carrier protein) reductase
APPPNAGC_01918 2.2e-214 siaT_2 G Tripartite ATP-independent periplasmic transporter, DctM component
APPPNAGC_01919 2.1e-83 dctQ1 G Tripartite ATP-independent periplasmic transporters, DctQ component
APPPNAGC_01920 7.2e-189 G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
APPPNAGC_01921 1.6e-132 K Transcriptional regulator
APPPNAGC_01922 9.1e-198 S response regulator aspartate phosphatase
APPPNAGC_01924 6.6e-35 S Protein of unknown function (DUF2642)
APPPNAGC_01925 2.8e-173 cat P Catalase
APPPNAGC_01926 1.4e-164 aadK G Streptomycin adenylyltransferase
APPPNAGC_01927 6.8e-248 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
APPPNAGC_01928 1e-59 hxlR K HxlR-like helix-turn-helix
APPPNAGC_01929 5.4e-161 S Belongs to the pirin family
APPPNAGC_01930 4e-91 K Bacterial regulatory proteins, tetR family
APPPNAGC_01931 3.4e-14
APPPNAGC_01932 3.5e-39 S Protein of unknown function (DUF418)
APPPNAGC_01933 1.8e-116 S Protein of unknown function (DUF418)
APPPNAGC_01934 2.6e-152 S response regulator aspartate phosphatase
APPPNAGC_01935 1.3e-68
APPPNAGC_01937 1.3e-34
APPPNAGC_01938 2.1e-149 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APPPNAGC_01939 3.6e-126 puuD 4.1.3.27 S Peptidase C26
APPPNAGC_01940 2e-200 S response regulator aspartate phosphatase
APPPNAGC_01941 8.6e-139 T helix_turn_helix, arabinose operon control protein
APPPNAGC_01942 1.4e-303 2.7.13.3 T Histidine kinase
APPPNAGC_01943 3.6e-291 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_01944 6.9e-198 fbpC2 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
APPPNAGC_01945 5.5e-189 P Bacterial extracellular solute-binding protein
APPPNAGC_01946 3.5e-212 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
APPPNAGC_01947 3.8e-187 G Tripartite ATP-independent periplasmic transporter, DctM component
APPPNAGC_01948 1.6e-69 G PFAM Tripartite ATP-independent periplasmic transporter, DctQ component
APPPNAGC_01949 3e-155 dctP G Bacterial extracellular solute-binding protein, family 7
APPPNAGC_01950 5.7e-240 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Aldehyde dehydrogenase family
APPPNAGC_01951 4.1e-171 gutB 1.1.1.14 E Dehydrogenase
APPPNAGC_01952 6e-175 ydjL 1.1.1.1, 1.1.1.14 E Glucose dehydrogenase C-terminus
APPPNAGC_01953 6.7e-152 2.2.1.1 G Transketolase
APPPNAGC_01954 3.2e-142 2.2.1.1 G 1-deoxy-D-xylulose-5-phosphate synthase
APPPNAGC_01955 8.4e-210 M carboxylic acid catabolic process
APPPNAGC_01956 4.4e-162 K Transcriptional regulator
APPPNAGC_01958 8.2e-85
APPPNAGC_01959 1.2e-227 3.5.1.47 S Peptidase dimerisation domain
APPPNAGC_01960 3.3e-225 3.5.1.47 S Peptidase dimerisation domain
APPPNAGC_01961 8.7e-249 P Sodium:sulfate symporter transmembrane region
APPPNAGC_01962 5e-221 E Peptidase family M28
APPPNAGC_01963 2.9e-193 E Belongs to the ABC transporter superfamily
APPPNAGC_01964 5.5e-186 oppD P Belongs to the ABC transporter superfamily
APPPNAGC_01965 1.3e-165 EP N-terminal TM domain of oligopeptide transport permease C
APPPNAGC_01966 1.2e-155 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_01967 1.3e-290 E Bacterial extracellular solute-binding proteins, family 5 Middle
APPPNAGC_01969 1.5e-163 K Transcriptional regulator
APPPNAGC_01971 3.4e-153 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
APPPNAGC_01972 2.3e-209 ybhE S Bacterial protein of unknown function (DUF871)
APPPNAGC_01973 2.8e-49 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
APPPNAGC_01974 2.3e-50 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
APPPNAGC_01975 1.9e-223 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APPPNAGC_01976 1.7e-45
APPPNAGC_01977 4.2e-250 celF 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APPPNAGC_01978 1e-137 S CAAX protease self-immunity
APPPNAGC_01979 1.9e-86 S Bacterial PH domain
APPPNAGC_01980 8.5e-263 ydbT S Bacterial PH domain
APPPNAGC_01983 1.1e-06
APPPNAGC_01985 1.8e-06
APPPNAGC_01986 3.9e-105 S LXG domain of WXG superfamily
APPPNAGC_01989 6.3e-69 ytcD5 K Transcriptional regulator
APPPNAGC_01990 8.4e-110 1.6.5.2 S NADPH-dependent FMN reductase
APPPNAGC_01991 1.1e-107 K intracellular protease amidase
APPPNAGC_01993 1.2e-22 S Domain of unknown function (DUF3784)
APPPNAGC_01994 1.2e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APPPNAGC_01995 1.7e-209 manC 2.7.7.13, 5.3.1.8 G mannose-1-phosphate guanylyltransferase
APPPNAGC_01996 1.7e-151 wcnD M Glycosyl Transferase
APPPNAGC_01997 6.2e-82 M Glycosyl transferases group 1
APPPNAGC_01998 2.4e-40
APPPNAGC_01999 4e-71 M Glycosyl transferases group 1
APPPNAGC_02000 5.2e-63 M TupA-like ATPgrasp
APPPNAGC_02001 1.2e-81 wzxA S Polysaccharide biosynthesis protein
APPPNAGC_02002 5.2e-111 cpsE M Bacterial sugar transferase
APPPNAGC_02003 2.9e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APPPNAGC_02004 3.3e-145 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APPPNAGC_02010 3.2e-187 S response regulator aspartate phosphatase
APPPNAGC_02011 6.7e-204 gerAC S Spore germination B3/ GerAC like, C-terminal
APPPNAGC_02012 2.2e-183 gerAB E Spore germination protein
APPPNAGC_02013 9.6e-224 gerAA EG Spore germination protein
APPPNAGC_02014 1e-19 4.2.1.113 S Nucleotidyltransferase domain
APPPNAGC_02015 6.8e-37 S Nucleotidyltransferase substrate binding protein like
APPPNAGC_02016 4.6e-199 C NADH:flavin oxidoreductase / NADH oxidase family
APPPNAGC_02017 1.3e-100 K Bacterial regulatory proteins, tetR family
APPPNAGC_02018 5.7e-80 S Bacterial PH domain
APPPNAGC_02019 9.4e-130 IQ Short-chain dehydrogenase reductase sdr
APPPNAGC_02020 2.9e-260 alsT E Sodium alanine symporter
APPPNAGC_02021 1.3e-117 mdmC 2.1.1.104 S O-methyltransferase
APPPNAGC_02022 1.5e-153 K LysR substrate binding domain
APPPNAGC_02023 2.2e-44 sdpR K transcriptional
APPPNAGC_02024 1.6e-101 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
APPPNAGC_02025 8e-138 MA20_35565 4.1.3.30 G Phosphoenolpyruvate phosphomutase
APPPNAGC_02026 4.4e-160 E Glyoxalase-like domain
APPPNAGC_02027 3.6e-185 P ABC transporter substrate-binding protein
APPPNAGC_02028 1.1e-138 P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
APPPNAGC_02029 8.2e-126 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
APPPNAGC_02030 3.2e-12
APPPNAGC_02031 9.6e-39
APPPNAGC_02032 5.9e-86 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
APPPNAGC_02033 6.2e-174 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
APPPNAGC_02034 9.4e-32 ulaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
APPPNAGC_02035 1.9e-180 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
APPPNAGC_02036 7.7e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
APPPNAGC_02037 1.4e-92 2.3.1.59 K Acetyltransferase (GNAT) domain
APPPNAGC_02038 6.1e-132 S Alpha/beta hydrolase family
APPPNAGC_02039 8.8e-38 T SpoVT / AbrB like domain
APPPNAGC_02040 1.3e-51 doc S Fic/DOC family
APPPNAGC_02041 3e-24
APPPNAGC_02044 1.8e-273 otrA J Elongation factor G, domain IV
APPPNAGC_02046 8.1e-224 S Putative esterase
APPPNAGC_02047 1.9e-89 yvdQ S Protein of unknown function (DUF3231)
APPPNAGC_02048 6.8e-36 ycbP S Protein of unknown function (DUF2512)
APPPNAGC_02049 1.3e-102 yqjF S Uncharacterized conserved protein (COG2071)
APPPNAGC_02050 7.2e-26 yqjF S Uncharacterized conserved protein (COG2071)
APPPNAGC_02052 2.6e-211 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
APPPNAGC_02053 5.1e-243 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
APPPNAGC_02054 1.8e-249 S Membrane
APPPNAGC_02055 2.4e-56 pucM 3.5.2.17 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
APPPNAGC_02056 1.3e-176 uox 1.7.3.3, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
APPPNAGC_02057 3e-87 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 S OHCU decarboxylase
APPPNAGC_02058 1.9e-308 pucR QT COG2508 Regulator of polyketide synthase expression
APPPNAGC_02059 2.3e-226 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
APPPNAGC_02060 2e-241 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
APPPNAGC_02061 3.6e-85 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
APPPNAGC_02062 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
APPPNAGC_02063 3.3e-153 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
APPPNAGC_02064 3.5e-106 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
APPPNAGC_02065 2.8e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
APPPNAGC_02066 1.4e-186 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
APPPNAGC_02067 6.4e-146 MA20_40340 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_02068 6.9e-139 P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
APPPNAGC_02069 3.3e-189 P NMT1-like family
APPPNAGC_02070 1.3e-143 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_02071 1.3e-137 P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
APPPNAGC_02072 0.0 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPPNAGC_02073 5.7e-183 cbrA5 P Ferrichrome ABC transporter substrate-binding protein
APPPNAGC_02074 9.8e-65 hit FG Scavenger mRNA decapping enzyme C-term binding
APPPNAGC_02075 5.7e-77 nsrR K Transcriptional regulator
APPPNAGC_02076 2e-77 6.3.3.2 S ASCH
APPPNAGC_02077 0.0 uidA G Belongs to the glycosyl hydrolase 2 family
APPPNAGC_02078 7.3e-150 fldX 1.1.1.31 I Domain of unknown function (DUF1932)
APPPNAGC_02079 1.9e-150 K Helix-turn-helix domain, rpiR family
APPPNAGC_02080 1.1e-107 H Methyltransferase
APPPNAGC_02081 9.1e-31
APPPNAGC_02082 6.3e-241 G Tripartite ATP-independent periplasmic transporter, DctM component
APPPNAGC_02083 1.2e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
APPPNAGC_02084 2.7e-179 K Transcriptional regulator
APPPNAGC_02085 1.3e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APPPNAGC_02086 7.3e-291 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
APPPNAGC_02087 2.3e-171 scrR K helix_turn _helix lactose operon repressor
APPPNAGC_02088 3.5e-34 S HAD-superfamily hydrolase, subfamily IIB
APPPNAGC_02089 9.7e-110 E ATPases associated with a variety of cellular activities
APPPNAGC_02090 2.6e-181 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_02091 3e-106 P Bacterial extracellular solute-binding protein
APPPNAGC_02092 2.4e-72 3.1.3.97 S Histidinol phosphatase
APPPNAGC_02093 2.3e-60 K Helix-turn-helix domain, rpiR family
APPPNAGC_02094 9.6e-115 drgA C nitroreductase
APPPNAGC_02095 1.3e-60 K helix_turn_helix, mercury resistance
APPPNAGC_02096 1.5e-115 P Pyridine nucleotide-disulphide oxidoreductase
APPPNAGC_02097 1.4e-08
APPPNAGC_02098 2.7e-132 ycsF S Belongs to the UPF0271 (lamB) family
APPPNAGC_02099 5.3e-207 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
APPPNAGC_02100 3.7e-177 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
APPPNAGC_02101 4e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
APPPNAGC_02102 2e-260 G Bacterial extracellular solute-binding protein
APPPNAGC_02103 5.6e-172 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_02104 4.6e-160 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_02106 1.3e-136 K helix_turn_helix, mercury resistance
APPPNAGC_02107 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
APPPNAGC_02109 9.8e-78
APPPNAGC_02110 2.1e-252 gltD 1.3.1.1 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
APPPNAGC_02111 6.5e-232 preA 1.3.1.1 CF dihydroorotate dehydrogenase
APPPNAGC_02112 6.1e-271 hyuA 3.5.2.2 F Amidohydrolase family
APPPNAGC_02113 1.5e-07
APPPNAGC_02114 3.8e-232 amaB 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
APPPNAGC_02115 9e-256 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APPPNAGC_02116 1.4e-40 F PFAM AIG2 family protein
APPPNAGC_02117 3.6e-42 S Integral membrane protein
APPPNAGC_02118 3.7e-225 K helix_turn_helix, arabinose operon control protein
APPPNAGC_02119 7.2e-257 S Hypothetical glycosyl hydrolase 6
APPPNAGC_02120 4.1e-225 G Bacterial extracellular solute-binding protein
APPPNAGC_02121 9.3e-129 G ABC transporter permease
APPPNAGC_02122 1.1e-146 G ABC-type polysaccharide transport system, permease component
APPPNAGC_02123 8.6e-274 3.2.1.23 G beta-galactosidase
APPPNAGC_02124 1.5e-238 S Hypothetical glycosyl hydrolase 6
APPPNAGC_02125 6.3e-109 glxR 1.1.1.31, 1.1.1.60 I 3-hydroxyisobutyrate dehydrogenase
APPPNAGC_02128 1.4e-167 S Tetratricopeptide repeat
APPPNAGC_02129 1.7e-274 cyaD 2.7.11.1, 3.1.4.52, 4.6.1.1 T Domain present in phytochromes and cGMP-specific phosphodiesterases.
APPPNAGC_02130 1.6e-266 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APPPNAGC_02131 7.7e-152 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
APPPNAGC_02132 3.2e-128 S Protein of unknown function (DUF3100)
APPPNAGC_02133 3.5e-71 S An automated process has identified a potential problem with this gene model
APPPNAGC_02134 6e-115 K Transcriptional regulator
APPPNAGC_02135 4.2e-131 GM NmrA-like family
APPPNAGC_02137 1.8e-110 V Domain of unknown function (DUF4162)
APPPNAGC_02138 1.9e-115 drrB V ABC-2 type transporter
APPPNAGC_02139 3.6e-172 tnpA1 L Transposase
APPPNAGC_02140 4.7e-131 K Helix-turn-helix XRE-family like proteins
APPPNAGC_02141 4.4e-236 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APPPNAGC_02142 6.4e-128 L DNA alkylation repair enzyme
APPPNAGC_02143 2.6e-113 S AAA domain
APPPNAGC_02144 5.2e-97 5.4.2.11 G Phosphoglycerate mutase family
APPPNAGC_02145 2.2e-194 yxjM T Signal transduction histidine kinase
APPPNAGC_02146 4.3e-107 KT LuxR family transcriptional regulator
APPPNAGC_02147 3.4e-169 V COG1131 ABC-type multidrug transport system, ATPase component
APPPNAGC_02148 7.2e-215 V ABC-2 family transporter protein
APPPNAGC_02149 9.1e-190 V ABC-2 type transporter
APPPNAGC_02150 2.1e-143 gspA M Glycosyl transferase family 8
APPPNAGC_02151 3.1e-57 yxjI S LURP-one-related
APPPNAGC_02152 6.8e-142 adcA P Belongs to the bacterial solute-binding protein 9 family
APPPNAGC_02153 3.2e-127 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APPPNAGC_02154 3.4e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
APPPNAGC_02155 4.9e-48
APPPNAGC_02156 3.8e-105 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APPPNAGC_02157 1.2e-272 MA20_17540 P secondary active sulfate transmembrane transporter activity
APPPNAGC_02158 0.0 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 F Belongs to the 5'-nucleotidase family
APPPNAGC_02159 4.9e-54 S Regulatory protein YrvL
APPPNAGC_02160 2.1e-188 yccF K SEC-C motif
APPPNAGC_02161 6.9e-257 sdcS P Sodium:sulfate symporter transmembrane region
APPPNAGC_02162 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
APPPNAGC_02163 1.7e-288 cstA T Carbon starvation protein
APPPNAGC_02164 3.9e-87
APPPNAGC_02165 9.4e-256 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APPPNAGC_02166 7.6e-203 pamO 1.14.13.22 P Flavin-binding monooxygenase-like
APPPNAGC_02167 3e-254 scrA5 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APPPNAGC_02168 0.0 bglX 3.2.1.21 GH3 G Belongs to the glycosyl hydrolase 3 family
APPPNAGC_02169 5.8e-266 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
APPPNAGC_02170 7e-150 rhaR2 K helix_turn_helix, arabinose operon control protein
APPPNAGC_02171 2.7e-166 yhcH V ABC transporter, ATP-binding protein
APPPNAGC_02172 1e-102 S ABC-2 family transporter protein
APPPNAGC_02173 1.8e-60 yhcF K Transcriptional regulator
APPPNAGC_02174 7.7e-118 V ATPases associated with a variety of cellular activities
APPPNAGC_02175 1.2e-105
APPPNAGC_02176 2.1e-196 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
APPPNAGC_02177 5e-81 dps P Belongs to the Dps family
APPPNAGC_02178 6e-97 S B3/4 domain
APPPNAGC_02179 5.4e-217 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
APPPNAGC_02180 2.9e-93 ogt 1.17.99.6, 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APPPNAGC_02181 2.4e-75 K Acetyltransferase (GNAT) domain
APPPNAGC_02182 3.3e-166 yhbB S Putative amidase domain
APPPNAGC_02183 4.3e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APPPNAGC_02184 4.3e-87 yufK S Family of unknown function (DUF5366)
APPPNAGC_02185 2.8e-51 hmoB 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
APPPNAGC_02186 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
APPPNAGC_02187 0.0 prkA T Ser protein kinase
APPPNAGC_02188 2.2e-86 sipV 3.4.21.89 U Belongs to the peptidase S26 family
APPPNAGC_02189 2.4e-101 sipV 3.4.21.89 U Belongs to the peptidase S26 family
APPPNAGC_02190 2.5e-138 cysA1 S AAA domain
APPPNAGC_02191 6.7e-215 yhbH S Belongs to the UPF0229 family
APPPNAGC_02194 2.2e-141 K Bacterial regulatory proteins, tetR family
APPPNAGC_02195 3.6e-266 EGP Major facilitator Superfamily
APPPNAGC_02196 1.1e-173 drrA V COG1131 ABC-type multidrug transport system, ATPase component
APPPNAGC_02197 2.8e-146 drrB V Transport permease protein
APPPNAGC_02198 3e-81 S Protein of unknown function (DUF664)
APPPNAGC_02199 1.9e-237 3.2.1.51, 4.2.2.23 GH95,PL11 G Right handed beta helix region
APPPNAGC_02200 3.5e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_02201 1.1e-248 E Sodium:solute symporter family
APPPNAGC_02202 7.8e-126 K UTRA
APPPNAGC_02203 1.2e-264 4.3.2.1 E argininosuccinate lyase
APPPNAGC_02204 3.7e-131 yvoA K transcriptional
APPPNAGC_02205 2.3e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
APPPNAGC_02206 2e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APPPNAGC_02207 8.2e-126 frp 1.5.1.39 C Oxidoreductase
APPPNAGC_02208 1.2e-219 mtnE 2.6.1.83 E Aminotransferase
APPPNAGC_02209 1.4e-113 ycgM Q Fumarylacetoacetate (FAA) hydrolase family
APPPNAGC_02210 3.4e-132 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
APPPNAGC_02211 7.1e-305 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
APPPNAGC_02212 7.5e-121 sfsA S Sugar fermentation stimulation protein
APPPNAGC_02213 4.2e-300 glpD 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
APPPNAGC_02214 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
APPPNAGC_02215 2.7e-271 ycgB S Stage V sporulation protein R
APPPNAGC_02216 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
APPPNAGC_02217 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
APPPNAGC_02218 1.5e-230 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APPPNAGC_02219 2.1e-149 htpX O Peptidase family M48
APPPNAGC_02220 7.2e-95 lemA S LemA family
APPPNAGC_02221 8.5e-218 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
APPPNAGC_02222 3.5e-255 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
APPPNAGC_02223 4.1e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
APPPNAGC_02224 1.6e-132 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
APPPNAGC_02225 2e-283 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APPPNAGC_02227 1.2e-214
APPPNAGC_02228 1.4e-78 K Sigma-70, region 4
APPPNAGC_02229 2.6e-205 msmK P Belongs to the ABC transporter superfamily
APPPNAGC_02230 5.5e-158 lrp QT PucR C-terminal helix-turn-helix domain
APPPNAGC_02231 4.1e-22
APPPNAGC_02232 1.2e-16 yheE S Family of unknown function (DUF5342)
APPPNAGC_02233 2.6e-203 yheB S Belongs to the UPF0754 family
APPPNAGC_02234 1.4e-54 yheA S Belongs to the UPF0342 family
APPPNAGC_02235 1.3e-156 yhaX S hydrolases of the HAD superfamily
APPPNAGC_02237 1.3e-40
APPPNAGC_02238 6.4e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_02239 8.5e-257 T PhoQ Sensor
APPPNAGC_02240 8.8e-181 yhaM L Shows a 3'-5' exoribonuclease activity
APPPNAGC_02241 4.4e-43 yhaL S Sporulation protein YhaL
APPPNAGC_02242 2.2e-161 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APPPNAGC_02244 1.1e-66 S Protein conserved in bacteria
APPPNAGC_02245 1e-107 hpr K Negative regulator of protease production and sporulation
APPPNAGC_02246 8.7e-49 yhaH D gas vesicle protein
APPPNAGC_02247 7.7e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
APPPNAGC_02248 1.2e-73 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
APPPNAGC_02249 7.1e-138 ecsA V transporter (ATP-binding protein)
APPPNAGC_02250 5.2e-210 ecsB U ABC transporter
APPPNAGC_02251 2.3e-125 ecsC S EcsC protein family
APPPNAGC_02252 4.1e-122 ccdA O cytochrome c biogenesis protein
APPPNAGC_02253 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APPPNAGC_02254 1.4e-200 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
APPPNAGC_02255 1.2e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
APPPNAGC_02256 4.9e-257 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
APPPNAGC_02258 1.3e-99 spo0B T Sporulation initiation phospho-transferase B, C-terminal
APPPNAGC_02259 7.6e-220 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APPPNAGC_02260 1.8e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
APPPNAGC_02261 2.1e-160 pheA 4.2.1.51 E Prephenate dehydratase
APPPNAGC_02262 1.6e-87 niaR S small molecule binding protein (contains 3H domain)
APPPNAGC_02263 6e-205 nifS 2.8.1.7 E Cysteine desulfurase
APPPNAGC_02264 1.2e-269 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
APPPNAGC_02265 6.3e-146 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
APPPNAGC_02266 1.8e-206 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
APPPNAGC_02267 1.4e-104 safA M spore coat assembly protein SafA
APPPNAGC_02268 3.3e-22 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APPPNAGC_02269 9.4e-62 1.9.3.1 C cytochrome c oxidase subunit II
APPPNAGC_02270 2e-86 bofC S BofC C-terminal domain
APPPNAGC_02271 1.3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APPPNAGC_02272 5.8e-183 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APPPNAGC_02273 1.4e-27 yrzS S Protein of unknown function (DUF2905)
APPPNAGC_02274 4e-187 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APPPNAGC_02275 8.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
APPPNAGC_02276 2.5e-37 yajC U Preprotein translocase subunit YajC
APPPNAGC_02277 1.1e-57 yrzE S Protein of unknown function (DUF3792)
APPPNAGC_02278 5.2e-70 ycaP S membrane
APPPNAGC_02279 1.4e-26 yodI
APPPNAGC_02280 3.2e-249 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APPPNAGC_02281 9.6e-22 yrzD S Post-transcriptional regulator
APPPNAGC_02282 6.7e-232 secD U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APPPNAGC_02283 2.7e-142 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APPPNAGC_02284 2.9e-37 yrvD S Lipopolysaccharide assembly protein A domain
APPPNAGC_02285 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
APPPNAGC_02286 1.2e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APPPNAGC_02287 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APPPNAGC_02288 6.3e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APPPNAGC_02289 9e-184 cytR 5.1.1.1 K LacI family transcriptional regulator
APPPNAGC_02290 3.6e-142 thuA G Trehalose utilisation
APPPNAGC_02291 1.1e-192 S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_02292 1.3e-201 V Belongs to the UPF0214 family
APPPNAGC_02294 1e-240 hisS 6.1.1.21 J histidyl-tRNA synthetase
APPPNAGC_02295 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
APPPNAGC_02296 8.2e-216 1.1.1.3 E homoserine dehydrogenase
APPPNAGC_02297 4e-50
APPPNAGC_02298 9.8e-216 yxjG 2.1.1.14 E Methionine synthase
APPPNAGC_02299 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
APPPNAGC_02300 7.2e-107 rsfA S Transcriptional regulator
APPPNAGC_02301 3.2e-231 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
APPPNAGC_02302 2.8e-70 cymR K Transcriptional regulator
APPPNAGC_02303 2.2e-210 iscS 2.8.1.7 E Cysteine desulfurase
APPPNAGC_02304 1.1e-216 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APPPNAGC_02305 4.5e-67 S COG0457 FOG TPR repeat
APPPNAGC_02306 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APPPNAGC_02307 3e-81 yrrD S protein conserved in bacteria
APPPNAGC_02308 2.1e-30 yrzR
APPPNAGC_02309 5.6e-184 yrrI S AI-2E family transporter
APPPNAGC_02310 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APPPNAGC_02311 1.2e-42 yrzL S Belongs to the UPF0297 family
APPPNAGC_02312 5.7e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APPPNAGC_02313 4.1e-25 yrzB S Belongs to the UPF0473 family
APPPNAGC_02314 1.2e-208 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APPPNAGC_02315 2.4e-113 yrrM 2.1.1.104 S O-methyltransferase
APPPNAGC_02316 5.3e-113 udk 2.7.1.48 F Cytidine monophosphokinase
APPPNAGC_02317 4.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APPPNAGC_02318 1.1e-11 S Protein of unknown function (DUF1510)
APPPNAGC_02319 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
APPPNAGC_02320 6e-149 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
APPPNAGC_02321 8.9e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APPPNAGC_02322 1.1e-10 S YrhC-like protein
APPPNAGC_02323 4.3e-77 M1-460
APPPNAGC_02324 2.8e-290 E Bacterial extracellular solute-binding proteins, family 5 Middle
APPPNAGC_02325 2.5e-147 appF P ATPases associated with a variety of cellular activities
APPPNAGC_02326 4.4e-141 oppD P Oligopeptide/dipeptide transporter, C-terminal region
APPPNAGC_02327 2e-155 EP N-terminal TM domain of oligopeptide transport permease C
APPPNAGC_02328 2.6e-145 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_02329 3.5e-106 arpR K Bacterial regulatory proteins, tetR family
APPPNAGC_02330 0.0 malS 3.2.1.1 GH13 G Carbohydrate binding domain
APPPNAGC_02331 1.7e-54 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APPPNAGC_02332 1.3e-103 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
APPPNAGC_02333 1.5e-186 lplJ 6.3.1.20 H Lipoate-protein ligase
APPPNAGC_02334 5.3e-251 S Membrane
APPPNAGC_02335 1.8e-223 hipO3 3.5.1.47 S amidohydrolase
APPPNAGC_02336 7.8e-161 ybaS 1.1.1.58 S Na -dependent transporter
APPPNAGC_02338 2.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APPPNAGC_02339 2.9e-176 yfjD P Transporter associated domain
APPPNAGC_02340 5.5e-25
APPPNAGC_02341 8.9e-23 S Histidine kinase
APPPNAGC_02343 2e-53
APPPNAGC_02344 2.1e-149 G Major facilitator Superfamily
APPPNAGC_02345 1.7e-20
APPPNAGC_02347 1e-96 ypbQ S protein conserved in bacteria
APPPNAGC_02348 5.2e-209 bcsA Q Naringenin-chalcone synthase
APPPNAGC_02349 5.6e-130 mta K transcriptional
APPPNAGC_02350 6.1e-114 rimJ2 J Acetyltransferase (GNAT) domain
APPPNAGC_02351 5e-273 uxaC 5.3.1.12 G glucuronate isomerase
APPPNAGC_02352 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
APPPNAGC_02353 3.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_02354 5.1e-131 xytR K DeoR C terminal sensor domain
APPPNAGC_02355 3.5e-86 ywrA P COG2059 Chromate transport protein ChrA
APPPNAGC_02356 2.9e-105 ywrB P COG2059 Chromate transport protein ChrA
APPPNAGC_02357 7.2e-155 mqnD S Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
APPPNAGC_02358 1.2e-112 mqnB 2.4.2.1, 3.2.2.26, 3.2.2.9 F Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
APPPNAGC_02359 3.9e-265 lipA1 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
APPPNAGC_02360 7.3e-275 K transcriptional antiterminator
APPPNAGC_02361 1.4e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
APPPNAGC_02362 0.0 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
APPPNAGC_02363 7.7e-162 Q calcium- and calmodulin-responsive adenylate cyclase activity
APPPNAGC_02364 1.8e-156 proX E Substrate binding domain of ABC-type glycine betaine transport system
APPPNAGC_02365 3.5e-100 K Belongs to the GbsR family
APPPNAGC_02366 8.6e-276 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
APPPNAGC_02367 4.3e-225 gbsB 1.1.1.1 C alcohol dehydrogenase
APPPNAGC_02368 1.8e-134 yvfI K COG2186 Transcriptional regulators
APPPNAGC_02369 1.8e-122 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
APPPNAGC_02370 6.6e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
APPPNAGC_02371 4.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
APPPNAGC_02372 0.0 lldP C L-lactate permease
APPPNAGC_02373 9.1e-14
APPPNAGC_02374 7.4e-225 cypA C Cytochrome P450
APPPNAGC_02375 3.1e-252 ydaH H AbgT putative transporter family
APPPNAGC_02376 0.0 htpG O Molecular chaperone. Has ATPase activity
APPPNAGC_02377 9.9e-100 yaaI Q Isochorismatase family
APPPNAGC_02378 1.2e-74 ygaO
APPPNAGC_02379 5.4e-27 K Transcriptional regulator
APPPNAGC_02380 1.8e-306 sasH 3.1.3.5, 3.6.1.45 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
APPPNAGC_02382 3.2e-289 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
APPPNAGC_02383 6.8e-284 prdR KT Transcriptional regulator
APPPNAGC_02384 3.7e-168 putA E Proline dehydrogenase
APPPNAGC_02385 1.5e-152 ykoQ S Calcineurin-like phosphoesterase superfamily domain
APPPNAGC_02386 8.2e-45 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APPPNAGC_02387 1.1e-284 S proteins of the AP superfamily
APPPNAGC_02389 1.5e-210 pbuG S permease
APPPNAGC_02390 9.9e-67
APPPNAGC_02391 3e-178 aph 2.7.11.1 S Phosphotransferase enzyme family
APPPNAGC_02392 3.4e-217 G Transmembrane secretion effector
APPPNAGC_02393 1.3e-23 S YfhD-like protein
APPPNAGC_02394 1e-63 dhaM 2.7.1.121 S PTS system fructose IIA component
APPPNAGC_02395 8.3e-108 dhaL 2.7.1.121 S Dak2
APPPNAGC_02396 7.4e-175 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
APPPNAGC_02397 1.2e-82 M1-431 S Protein of unknown function (DUF1706)
APPPNAGC_02398 1.3e-73 adcR K Iron dependent repressor, N-terminal DNA binding domain
APPPNAGC_02399 3.7e-197 yvmA EGP Major Facilitator Superfamily
APPPNAGC_02400 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APPPNAGC_02401 2.1e-230 ulaA 2.7.1.194 S PTS system ascorbate-specific transporter subunit IIC
APPPNAGC_02402 8.9e-41 ulaB_1 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
APPPNAGC_02403 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT COG3711 Transcriptional antiterminator
APPPNAGC_02404 2e-181 yxeA V FtsX-like permease family
APPPNAGC_02405 7.2e-113 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
APPPNAGC_02406 3.8e-80 K Bacterial regulatory proteins, tetR family
APPPNAGC_02407 1.8e-20 yisL S UPF0344 protein
APPPNAGC_02408 6.3e-122 C Nitroreductase family
APPPNAGC_02409 2.2e-84 tetB EGP Major facilitator Superfamily
APPPNAGC_02410 1.4e-57 K helix_turn_helix multiple antibiotic resistance protein
APPPNAGC_02411 3.8e-09 yqkA K GrpB protein
APPPNAGC_02412 4.1e-81 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APPPNAGC_02413 4.5e-22 S Carboxymuconolactone decarboxylase family
APPPNAGC_02414 1.1e-129 K TIGRFAM RNA polymerase sigma factor, sigma-70 family
APPPNAGC_02415 3e-22 L Transposase
APPPNAGC_02416 2.1e-197 S Erythromycin esterase
APPPNAGC_02417 4.2e-167 K LysR substrate binding domain
APPPNAGC_02418 1.8e-184 ord 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
APPPNAGC_02419 1.8e-235 C Na+/H+ antiporter family
APPPNAGC_02420 1e-75 S glyoxalase bleomycin resistance protein dioxygenase
APPPNAGC_02421 3.6e-44 K helix_turn_helix, Arsenical Resistance Operon Repressor
APPPNAGC_02422 2.7e-96 S Activator of Hsp90 ATPase 1 family protein
APPPNAGC_02423 2.8e-128
APPPNAGC_02424 1.2e-79 S glyoxalase bleomycin resistance protein dioxygenase
APPPNAGC_02425 5.3e-134 K helix_turn_helix, arabinose operon control protein
APPPNAGC_02426 3.8e-105 S GrpB protein
APPPNAGC_02427 4.4e-101 pksA K BetI-type transcriptional repressor, C-terminal
APPPNAGC_02428 2.5e-116 S Sap, sulfolipid-1-addressing protein
APPPNAGC_02429 5.4e-33
APPPNAGC_02430 5.2e-166 I transferase activity, transferring acyl groups other than amino-acyl groups
APPPNAGC_02431 2.4e-72 phyR K Sigma-70, region 4
APPPNAGC_02432 2e-39 S Helix-turn-helix domain
APPPNAGC_02433 1.1e-26 S Domain of unknown function (DUF3173)
APPPNAGC_02434 5.8e-230 L Belongs to the 'phage' integrase family
APPPNAGC_02435 5.4e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
APPPNAGC_02436 0.0 yebA E COG1305 Transglutaminase-like enzymes
APPPNAGC_02437 1.3e-205 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
APPPNAGC_02438 2.2e-171 yeaC S COG0714 MoxR-like ATPases
APPPNAGC_02439 3.8e-99 CO Thioredoxin
APPPNAGC_02440 6e-182 3.1.4.53 Q Calcineurin-like phosphoesterase
APPPNAGC_02442 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
APPPNAGC_02443 5e-107 C nitroreductase
APPPNAGC_02444 4e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APPPNAGC_02445 6e-62 S Bacteriophage holin family
APPPNAGC_02447 0.0 L Phage minor structural protein
APPPNAGC_02448 2.6e-132 S Phage tail protein
APPPNAGC_02449 1.6e-114 D Phage tail tape measure protein, TP901 family
APPPNAGC_02450 2.8e-76
APPPNAGC_02451 1.3e-70
APPPNAGC_02452 8.7e-55 S Short C-terminal domain
APPPNAGC_02453 2.2e-210 mez_1 1.1.1.38 C Malate dehydrogenase
APPPNAGC_02454 8.7e-243 maeN C COG3493 Na citrate symporter
APPPNAGC_02455 1.2e-110 dcuR T COG4565 Response regulator of citrate malate metabolism
APPPNAGC_02456 1.5e-244 malK 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APPPNAGC_02457 9.6e-71 wecC 1.1.1.336 M ArpU family transcriptional regulator
APPPNAGC_02458 2.2e-148 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APPPNAGC_02459 1.7e-117 ehuD E Binding-protein-dependent transport system inner membrane component
APPPNAGC_02460 9.4e-113 ehuC E Binding-protein-dependent transport system inner membrane component
APPPNAGC_02461 1.7e-148 ehuB ET Bacterial periplasmic substrate-binding proteins
APPPNAGC_02462 2.3e-132
APPPNAGC_02463 1.6e-151 S Haloacid dehalogenase-like hydrolase
APPPNAGC_02464 2.3e-181 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
APPPNAGC_02465 1.2e-68 wxcN GT2 S GtrA-like protein
APPPNAGC_02466 0.0 yfhO S Bacterial membrane protein YfhO
APPPNAGC_02469 3.1e-28 MA20_19235 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
APPPNAGC_02470 6.3e-40 MA20_19235 S Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
APPPNAGC_02471 1e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
APPPNAGC_02472 1.8e-105 yjgD S Protein of unknown function (DUF1641)
APPPNAGC_02473 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
APPPNAGC_02474 7.8e-138 focA P Formate/nitrite transporter
APPPNAGC_02475 6.9e-34 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
APPPNAGC_02476 1.1e-74 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
APPPNAGC_02477 8.1e-88 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
APPPNAGC_02478 2.2e-235 moeA 2.10.1.1 H molybdopterin
APPPNAGC_02479 1.4e-181 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
APPPNAGC_02480 2.8e-82 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
APPPNAGC_02481 5.6e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
APPPNAGC_02482 8.7e-87 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
APPPNAGC_02483 1e-265 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
APPPNAGC_02484 1.5e-141 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APPPNAGC_02485 7.4e-121 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
APPPNAGC_02486 5.1e-128 S carbohydrate derivative metabolic process
APPPNAGC_02487 1.9e-223 ulaA S PTS system ascorbate-specific transporter subunit IIC
APPPNAGC_02488 1.4e-41 2.7.1.194, 2.7.1.200 G COG3414 Phosphotransferase system, galactitol-specific IIB component
APPPNAGC_02489 1.8e-72 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APPPNAGC_02490 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
APPPNAGC_02491 1.6e-123 C Zinc-binding dehydrogenase
APPPNAGC_02492 9.7e-42 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APPPNAGC_02493 1e-114 K Bacterial regulatory helix-turn-helix protein, lysR family
APPPNAGC_02494 6.4e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APPPNAGC_02495 5.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APPPNAGC_02496 1.5e-116 ydiL S CAAX protease self-immunity
APPPNAGC_02498 2.3e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
APPPNAGC_02499 7e-142 P COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
APPPNAGC_02500 3.9e-111 metI P COG2011 ABC-type metal ion transport system, permease component
APPPNAGC_02501 1.3e-182 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APPPNAGC_02502 7.9e-130 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
APPPNAGC_02503 1.4e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
APPPNAGC_02504 6.8e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APPPNAGC_02505 3e-305 ydiF S ABC transporter
APPPNAGC_02506 2.8e-177 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APPPNAGC_02507 1.2e-85 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
APPPNAGC_02508 1.2e-126 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
APPPNAGC_02509 7.8e-80 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
APPPNAGC_02510 7.2e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
APPPNAGC_02513 4.4e-211 megL 2.5.1.48, 2.5.1.49, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
APPPNAGC_02514 1.7e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APPPNAGC_02515 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APPPNAGC_02516 1.3e-120 sapB S MgtC SapB transporter
APPPNAGC_02517 2.7e-189 V Domain of unknown function (DUF3471)
APPPNAGC_02518 4.8e-67 puuR K sequence-specific DNA binding
APPPNAGC_02519 5.6e-69 puuR K sequence-specific DNA binding
APPPNAGC_02520 1.4e-303 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
APPPNAGC_02521 1.4e-226 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APPPNAGC_02522 3.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
APPPNAGC_02523 1.7e-105 4.2.1.1 P Reversible hydration of carbon dioxide
APPPNAGC_02524 6.1e-100 ytqB J Putative rRNA methylase
APPPNAGC_02526 4.5e-190 yttB EGP Major facilitator Superfamily
APPPNAGC_02527 3e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
APPPNAGC_02528 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
APPPNAGC_02529 8.8e-237 3.5.1.47 S amidohydrolase
APPPNAGC_02530 8.2e-132 S Protein of unknown function (DUF3100)
APPPNAGC_02531 2.1e-77 S An automated process has identified a potential problem with this gene model
APPPNAGC_02532 2.3e-205 ytfP S HI0933-like protein
APPPNAGC_02533 1.1e-225 yhaA1 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
APPPNAGC_02534 1.1e-68 yugU S Uncharacterised protein family UPF0047
APPPNAGC_02535 1.7e-162 yvrE G SMP-30/Gluconolaconase/LRE-like region
APPPNAGC_02536 4.6e-283 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APPPNAGC_02537 3.4e-195 ftsW D Belongs to the SEDS family
APPPNAGC_02538 1.9e-209 rodA D Belongs to the SEDS family
APPPNAGC_02539 1.5e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
APPPNAGC_02540 1.5e-30 ytzE K COG1349 Transcriptional regulators of sugar metabolism
APPPNAGC_02541 1.8e-75 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
APPPNAGC_02542 5e-54 ydaF_2 2.3.1.128 J Acetyltransferases including N-acetylases of ribosomal proteins
APPPNAGC_02543 1.3e-97 C oxidoreductases (related to aryl-alcohol dehydrogenases)
APPPNAGC_02544 1.3e-108 K Helix-turn-helix XRE-family like proteins
APPPNAGC_02545 1.8e-159 ydeE K AraC family transcriptional regulator
APPPNAGC_02546 4.1e-167 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APPPNAGC_02547 3.1e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
APPPNAGC_02548 8.6e-61 cidA S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
APPPNAGC_02549 6.9e-98 lrgB M effector of murein hydrolase
APPPNAGC_02550 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
APPPNAGC_02551 4.5e-207 1.8.1.4 C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
APPPNAGC_02552 1.1e-175 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APPPNAGC_02553 6e-191 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APPPNAGC_02554 6.9e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APPPNAGC_02555 1.8e-50 S PFAM Uncharacterised protein family UPF0150
APPPNAGC_02556 1.1e-125 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_02557 7.5e-163 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
APPPNAGC_02558 3.8e-153 ytmP 2.7.1.89 M Phosphotransferase
APPPNAGC_02559 1.8e-13 S YtzH-like protein
APPPNAGC_02560 1.9e-118 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APPPNAGC_02561 8.2e-48 ytzB
APPPNAGC_02562 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
APPPNAGC_02563 3.8e-85 yjjX F Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
APPPNAGC_02564 2.7e-76 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
APPPNAGC_02565 3.4e-114 S Phosphotransferase system, EIIC
APPPNAGC_02566 1.7e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
APPPNAGC_02567 3.8e-145 ytpQ S Belongs to the UPF0354 family
APPPNAGC_02568 1.6e-103 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APPPNAGC_02569 1.6e-308 sftA D Belongs to the FtsK SpoIIIE SftA family
APPPNAGC_02570 4.2e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
APPPNAGC_02571 4.3e-63 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APPPNAGC_02572 1.1e-15 XK27_07760 S COG4980 Gas vesicle protein
APPPNAGC_02573 1.2e-197 aroA 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
APPPNAGC_02574 6.6e-185 ccpA K catabolite control protein A
APPPNAGC_02575 1e-231 acuC BQ histone deacetylase
APPPNAGC_02576 5e-111 acuB S Acetoin utilization protein AcuB
APPPNAGC_02577 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
APPPNAGC_02578 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
APPPNAGC_02579 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M COG0744 Membrane carboxypeptidase (penicillin-binding protein)
APPPNAGC_02580 2.2e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APPPNAGC_02581 3.9e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APPPNAGC_02582 1.2e-85 ytsP 1.8.4.14 T GAF domain-containing protein
APPPNAGC_02583 5.9e-81 L Transposase
APPPNAGC_02584 2.3e-113 yttP K Transcriptional regulator
APPPNAGC_02585 8.5e-142 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
APPPNAGC_02586 1.6e-297 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APPPNAGC_02587 8e-205 iscS2 2.8.1.7 E Cysteine desulfurase
APPPNAGC_02588 7.6e-222 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APPPNAGC_02589 8.1e-28 sspB S spore protein
APPPNAGC_02590 5.5e-178 sppA OU signal peptide peptidase SppA
APPPNAGC_02591 1.3e-96 yteJ S RDD family
APPPNAGC_02592 4e-119 ytfI S Protein of unknown function (DUF2953)
APPPNAGC_02593 6e-73 ytfJ S Sporulation protein YtfJ
APPPNAGC_02594 6.2e-192 ywoG EGP Major facilitator Superfamily
APPPNAGC_02595 1.4e-84 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APPPNAGC_02596 1.7e-179 ytxK 2.1.1.72 L DNA methylase
APPPNAGC_02597 2.5e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APPPNAGC_02598 3.2e-167 yhaM S 3'-5' exoribonuclease yhaM
APPPNAGC_02599 4.6e-10 S EcsC protein family
APPPNAGC_02600 1.4e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
APPPNAGC_02601 1.1e-256 argH 4.3.2.1 E argininosuccinate lyase
APPPNAGC_02603 2.6e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_02604 1e-63
APPPNAGC_02605 6.8e-201 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
APPPNAGC_02606 7.6e-126 ytkL S Belongs to the UPF0173 family
APPPNAGC_02608 6.7e-240 ytoI K transcriptional regulator containing CBS domains
APPPNAGC_02609 4.6e-08 ytpI S YtpI-like protein
APPPNAGC_02610 1e-165 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
APPPNAGC_02611 4.2e-89 ytrI
APPPNAGC_02612 7.2e-53 ytrH S Sporulation protein YtrH
APPPNAGC_02613 0.0 dnaE 2.7.7.7 L DNA polymerase
APPPNAGC_02614 3.4e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
APPPNAGC_02615 5.8e-115 lutR_1 K helix_turn_helix gluconate operon transcriptional repressor
APPPNAGC_02616 6.8e-153 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APPPNAGC_02617 7.6e-180 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
APPPNAGC_02618 2.2e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APPPNAGC_02619 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
APPPNAGC_02620 3.8e-61 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
APPPNAGC_02621 6.7e-73 yeaL S UPF0756 membrane protein
APPPNAGC_02622 2.1e-205 citZ 2.3.3.1 C Belongs to the citrate synthase family
APPPNAGC_02623 4.5e-241 icd 1.1.1.42 C isocitrate
APPPNAGC_02624 2.6e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
APPPNAGC_02625 2.2e-73 lrpC K helix_turn_helix ASNC type
APPPNAGC_02626 1.5e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_02627 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
APPPNAGC_02628 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APPPNAGC_02629 5.5e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APPPNAGC_02630 1.3e-103 ytaF P Probably functions as a manganese efflux pump
APPPNAGC_02631 4.2e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APPPNAGC_02632 3.2e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APPPNAGC_02633 5.4e-68 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
APPPNAGC_02634 3.3e-65
APPPNAGC_02635 5.1e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APPPNAGC_02636 3.9e-241 dnaB L Membrane attachment protein
APPPNAGC_02637 3.6e-171 dnaI L Primosomal protein DnaI
APPPNAGC_02638 1.1e-222 mqnC 1.21.98.1, 2.5.1.120, 2.5.1.77 H Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)
APPPNAGC_02639 3.1e-161 ytxC S YtxC-like family
APPPNAGC_02640 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APPPNAGC_02641 3.4e-183 S Oxidoreductase family, NAD-binding Rossmann fold
APPPNAGC_02642 2.4e-175 strT C Aldo/keto reductase family
APPPNAGC_02643 2.2e-263 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
APPPNAGC_02644 2.5e-122
APPPNAGC_02645 5.3e-232 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APPPNAGC_02646 1.2e-118 macB V ABC transporter, ATP-binding protein
APPPNAGC_02647 2e-206 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
APPPNAGC_02648 2.1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APPPNAGC_02649 1.7e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
APPPNAGC_02650 2.3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APPPNAGC_02651 7.9e-52 S Protein of unknown function, DUF485
APPPNAGC_02652 1.8e-260 actP S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APPPNAGC_02653 1.7e-64 ysdB S Sigma-w pathway protein YsdB
APPPNAGC_02654 1.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
APPPNAGC_02655 7.7e-180 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
APPPNAGC_02656 6.2e-137 ytlC P ABC transporter
APPPNAGC_02657 5.5e-136 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
APPPNAGC_02658 3.3e-83 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
APPPNAGC_02659 1.2e-222 ymfD EGP Major facilitator Superfamily
APPPNAGC_02660 7.9e-85 ywpF S YwpF-like protein
APPPNAGC_02662 4.3e-219 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
APPPNAGC_02663 1.3e-111 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
APPPNAGC_02664 8.2e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
APPPNAGC_02665 1.3e-105 mrr V Restriction endonuclease
APPPNAGC_02666 1.6e-169 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
APPPNAGC_02667 2.6e-149 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
APPPNAGC_02668 1e-152 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPPNAGC_02669 2.4e-162 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPPNAGC_02670 1.5e-99 pgpB3 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
APPPNAGC_02671 1.1e-232 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APPPNAGC_02672 2.1e-74 S Putative small multi-drug export protein
APPPNAGC_02673 1.3e-73 S DinB superfamily
APPPNAGC_02674 6.4e-58 S Protein of unknown function (DUF1516)
APPPNAGC_02675 2e-83 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
APPPNAGC_02676 6.2e-163 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
APPPNAGC_02677 2.5e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
APPPNAGC_02678 1e-37 yeaO S Protein of unknown function, DUF488
APPPNAGC_02680 6.7e-26
APPPNAGC_02681 3.1e-41
APPPNAGC_02683 9.7e-22 xhlB S SPP1 phage holin
APPPNAGC_02684 3.4e-55 3.5.1.28 V N-Acetylmuramoyl-L-alanine amidase
APPPNAGC_02687 2.1e-94 L Prophage endopeptidase tail
APPPNAGC_02688 1.3e-22
APPPNAGC_02689 3e-29 S IMG reference gene
APPPNAGC_02690 6.1e-49 S Phage tail protein
APPPNAGC_02691 5.1e-60 S Phage-related minor tail protein
APPPNAGC_02692 5.9e-24 V Restriction endonuclease
APPPNAGC_02693 1e-09 S Phage tail tape measure protein, TP901 family
APPPNAGC_02694 8.4e-39 S Phage tail assembly chaperone protein, TAC
APPPNAGC_02695 1.5e-13 N Bacterial Ig-like domain 2
APPPNAGC_02696 4.4e-61 S Phage tail tube protein
APPPNAGC_02700 2.2e-07 K cell adhesion
APPPNAGC_02704 6.1e-154 S Family of unknown function (DUF5309)
APPPNAGC_02705 1.8e-37
APPPNAGC_02706 3.7e-191 S Phage portal protein, SPP1 Gp6-like
APPPNAGC_02707 2.4e-248 S TIGRFAM Phage
APPPNAGC_02708 8.3e-37 S Helix-turn-helix of insertion element transposase
APPPNAGC_02710 1.3e-14
APPPNAGC_02711 6.8e-08
APPPNAGC_02714 2.5e-11
APPPNAGC_02717 3.7e-33
APPPNAGC_02719 1.5e-42 2.7.1.24 H dephospho-CoA kinase activity
APPPNAGC_02721 7.2e-29 S protein conserved in bacteria
APPPNAGC_02723 5.3e-98 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
APPPNAGC_02725 5.9e-43 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
APPPNAGC_02730 1.3e-126 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APPPNAGC_02731 1.5e-310 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APPPNAGC_02732 2.3e-25 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
APPPNAGC_02736 2e-33 3.1.22.4 S Crossover junction endodeoxyribonuclease RuvC
APPPNAGC_02737 7.2e-125
APPPNAGC_02738 1.8e-180 L DNA polymerase A domain
APPPNAGC_02739 1.8e-16
APPPNAGC_02740 6.5e-30
APPPNAGC_02742 3.4e-45
APPPNAGC_02745 3.9e-11
APPPNAGC_02746 6.3e-09 S Cro/C1-type HTH DNA-binding domain
APPPNAGC_02747 7.1e-49
APPPNAGC_02748 2.3e-59 L Toprim-like
APPPNAGC_02749 4.2e-12
APPPNAGC_02750 4.1e-128 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
APPPNAGC_02752 1.1e-58 L DNA-dependent DNA replication
APPPNAGC_02753 1.8e-12
APPPNAGC_02756 3.5e-33
APPPNAGC_02763 3.1e-09
APPPNAGC_02765 2.2e-40 S Helix-turn-helix domain
APPPNAGC_02767 7.1e-12
APPPNAGC_02768 7e-123 L Belongs to the 'phage' integrase family
APPPNAGC_02769 3.3e-19
APPPNAGC_02770 8.8e-69 yugN S YugN-like family
APPPNAGC_02771 3.1e-256 pgi 5.3.1.9 G Belongs to the GPI family
APPPNAGC_02772 1.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
APPPNAGC_02773 3.3e-222 yugK C oxidoreductases, Fe-dependent alcohol dehydrogenase family
APPPNAGC_02774 1.2e-33 yuzA S Domain of unknown function (DUF378)
APPPNAGC_02775 3.3e-52 J RNA binding protein (contains ribosomal protein S1 domain)
APPPNAGC_02776 1.6e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
APPPNAGC_02777 3e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
APPPNAGC_02778 1.4e-220 yugH 2.6.1.1 E Aminotransferase
APPPNAGC_02779 1.2e-83 alaR K Transcriptional regulator
APPPNAGC_02780 1.2e-85 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APPPNAGC_02781 1.4e-142 yihY S Belongs to the UPF0761 family
APPPNAGC_02782 1.9e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APPPNAGC_02783 2.4e-229 S antiporter
APPPNAGC_02784 2.7e-45
APPPNAGC_02785 5.6e-275 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
APPPNAGC_02786 1.5e-77 yuiD S protein conserved in bacteria
APPPNAGC_02787 1.7e-108 yuiC S protein conserved in bacteria
APPPNAGC_02788 2.2e-46 yuiB S Putative membrane protein
APPPNAGC_02789 1.9e-228 yumB 1.6.99.3 C NADH dehydrogenase
APPPNAGC_02790 2.1e-185 ycgT 1.18.1.2, 1.19.1.1 C reductase
APPPNAGC_02791 6e-205 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
APPPNAGC_02792 3.7e-70 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
APPPNAGC_02793 0.0 mtlR K transcriptional regulator, MtlR
APPPNAGC_02794 1.4e-306 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
APPPNAGC_02795 4.4e-152 yckB ET Belongs to the bacterial solute-binding protein 3 family
APPPNAGC_02796 3.1e-108 yecS P COG0765 ABC-type amino acid transport system, permease component
APPPNAGC_02797 6.4e-60 erpA S Belongs to the HesB IscA family
APPPNAGC_02798 7.6e-09 S Spo0E like sporulation regulatory protein
APPPNAGC_02799 1.9e-208 mqnE 1.21.98.1, 2.5.1.120, 2.5.1.77 H Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
APPPNAGC_02800 5.8e-160 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APPPNAGC_02801 1.4e-42
APPPNAGC_02802 2.2e-40 yuzB S Belongs to the UPF0349 family
APPPNAGC_02803 0.0 yutJ 1.6.99.3 C NADH dehydrogenase
APPPNAGC_02804 2.8e-51 yuzD S protein conserved in bacteria
APPPNAGC_02805 9.7e-36 yutI O COG0694 Thioredoxin-like proteins and domains
APPPNAGC_02806 8.9e-159 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
APPPNAGC_02807 1.5e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
APPPNAGC_02808 4.8e-238 hom 1.1.1.3 E homoserine dehydrogenase
APPPNAGC_02809 2e-202 yutH S Spore coat protein
APPPNAGC_02810 4.6e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
APPPNAGC_02811 1.2e-129 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APPPNAGC_02812 2.2e-73 yutE S Protein of unknown function DUF86
APPPNAGC_02813 1.3e-43
APPPNAGC_02814 3.7e-50 yutD S protein conserved in bacteria
APPPNAGC_02815 5.7e-92 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APPPNAGC_02816 3.5e-174 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
APPPNAGC_02817 5.3e-200 lytH M Peptidase, M23
APPPNAGC_02818 1e-275 nhaC C Na+/H+ antiporter family
APPPNAGC_02819 5.1e-139 yunB S Sporulation protein YunB (Spo_YunB)
APPPNAGC_02820 9e-89 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APPPNAGC_02821 6.2e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APPPNAGC_02822 9.9e-49 yunC S Domain of unknown function (DUF1805)
APPPNAGC_02823 1.4e-256 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
APPPNAGC_02824 2.5e-139 yunE S membrane transporter protein
APPPNAGC_02825 2.7e-165 yunF S Protein of unknown function DUF72
APPPNAGC_02826 2.1e-178 L Transposase
APPPNAGC_02827 2.5e-62 S Domain of unknown function (DUF5082)
APPPNAGC_02828 9e-29
APPPNAGC_02829 2.5e-86
APPPNAGC_02830 1.2e-09
APPPNAGC_02831 5.9e-202 ysdC G COG1363 Cellulase M and related proteins
APPPNAGC_02832 1.1e-17
APPPNAGC_02834 6.3e-31 sspI S Belongs to the SspI family
APPPNAGC_02835 4.3e-127 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APPPNAGC_02836 4.9e-193 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APPPNAGC_02837 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APPPNAGC_02838 3.4e-33 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
APPPNAGC_02839 3.3e-84 cvpA S membrane protein, required for colicin V production
APPPNAGC_02840 0.0 polX L COG1796 DNA polymerase IV (family X)
APPPNAGC_02841 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APPPNAGC_02842 6.9e-66 yshE S membrane
APPPNAGC_02843 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APPPNAGC_02844 3.3e-101 fadR K Transcriptional regulator
APPPNAGC_02845 8.8e-131 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
APPPNAGC_02846 2.5e-133 etfB C Electron transfer flavoprotein
APPPNAGC_02847 1.5e-172 etfA C Electron transfer flavoprotein
APPPNAGC_02848 1.8e-53 trxA O Belongs to the thioredoxin family
APPPNAGC_02849 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APPPNAGC_02850 1.3e-75 yslB S Protein of unknown function (DUF2507)
APPPNAGC_02851 4.7e-228 ktrB P COG0168 Trk-type K transport systems, membrane components
APPPNAGC_02852 2.7e-111 sdhC C succinate dehydrogenase
APPPNAGC_02853 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
APPPNAGC_02854 6.1e-145 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
APPPNAGC_02855 1.9e-77 fcbC S thioesterase
APPPNAGC_02856 1.6e-32 gerE K Transcriptional regulator
APPPNAGC_02857 1.3e-38 ptsH G phosphocarrier protein HPr
APPPNAGC_02858 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APPPNAGC_02859 1.2e-79 ysmB 2.4.2.28 K transcriptional
APPPNAGC_02860 4.5e-149 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
APPPNAGC_02861 2.5e-23 C 4Fe-4S binding domain
APPPNAGC_02862 9.2e-194 yceA S Belongs to the UPF0176 family
APPPNAGC_02863 5.9e-176 gerM S COG5401 Spore germination protein
APPPNAGC_02864 2e-135 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
APPPNAGC_02865 1.7e-105 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APPPNAGC_02866 4.4e-94 ysnB S Phosphoesterase
APPPNAGC_02869 1.1e-305 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
APPPNAGC_02870 3.9e-268 M Glycosyl transferase family group 2
APPPNAGC_02871 4.6e-70
APPPNAGC_02872 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
APPPNAGC_02873 0.0 ilvB 2.2.1.6 E Acetolactate synthase
APPPNAGC_02874 4.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
APPPNAGC_02875 7.5e-178 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
APPPNAGC_02876 2.4e-281 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
APPPNAGC_02877 8e-194 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
APPPNAGC_02878 3.1e-267 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APPPNAGC_02879 2.1e-111 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APPPNAGC_02880 3.2e-178 trxA2 O COG0457 FOG TPR repeat
APPPNAGC_02881 7.4e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APPPNAGC_02882 1e-237 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APPPNAGC_02883 1.4e-306 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
APPPNAGC_02884 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
APPPNAGC_02885 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
APPPNAGC_02886 1.7e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
APPPNAGC_02887 1.6e-146 hemX O cytochrome C
APPPNAGC_02888 6.6e-165 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
APPPNAGC_02889 5.4e-133 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
APPPNAGC_02890 2.6e-180 hemB 4.2.1.24 H Belongs to the ALAD family
APPPNAGC_02891 1.8e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
APPPNAGC_02892 7.6e-155 spoVID M stage VI sporulation protein D
APPPNAGC_02893 2.4e-156
APPPNAGC_02894 1.7e-187 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
APPPNAGC_02895 9.8e-103
APPPNAGC_02896 1.1e-27
APPPNAGC_02897 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APPPNAGC_02898 1e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
APPPNAGC_02899 2.1e-118 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
APPPNAGC_02900 1e-193
APPPNAGC_02901 0.0 yuxL 3.4.19.1 EU peptidase
APPPNAGC_02902 4.2e-101 maf D septum formation protein Maf
APPPNAGC_02903 2.8e-120 radC E Belongs to the UPF0758 family
APPPNAGC_02904 1.5e-186 mreB D Rod shape-determining protein MreB
APPPNAGC_02905 7.4e-158 mreC M Involved in formation and maintenance of cell shape
APPPNAGC_02906 1.3e-72 mreD M shape-determining protein
APPPNAGC_02907 2.5e-121 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
APPPNAGC_02908 2.8e-140 minD D Belongs to the ParA family
APPPNAGC_02909 3e-90 yfkM 3.5.1.124 S protease
APPPNAGC_02910 1.4e-72 moaC 4.6.1.17 H MoaC family
APPPNAGC_02911 1.3e-91 bioY S BioY family
APPPNAGC_02912 2.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
APPPNAGC_02913 3.9e-128 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
APPPNAGC_02914 1.8e-133 spoIVFB S Stage IV sporulation protein
APPPNAGC_02915 1.3e-266 rng J ribonuclease, Rne Rng family
APPPNAGC_02916 2.2e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
APPPNAGC_02917 1.8e-56 ysxB J ribosomal protein
APPPNAGC_02918 1.7e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
APPPNAGC_02919 4e-44 abrB K SpoVT / AbrB like domain
APPPNAGC_02920 4.7e-213 Q COG1228 Imidazolonepropionase and related amidohydrolases
APPPNAGC_02922 3.5e-117 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
APPPNAGC_02923 2.7e-205 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
APPPNAGC_02924 6.5e-128 S Peptidase C26
APPPNAGC_02925 3.9e-268 nylA 3.5.1.4 J Belongs to the amidase family
APPPNAGC_02926 1.3e-76 S DinB family
APPPNAGC_02927 1e-165 pstS P Phosphate
APPPNAGC_02928 6.4e-160 pstC P probably responsible for the translocation of the substrate across the membrane
APPPNAGC_02929 1.2e-160 pstA P Phosphate transport system permease
APPPNAGC_02930 4.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APPPNAGC_02931 1.4e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APPPNAGC_02932 6.1e-109 phoU P Plays a role in the regulation of phosphate uptake
APPPNAGC_02933 7.8e-61
APPPNAGC_02934 0.0 addB 3.6.4.12 L exonuclease activity
APPPNAGC_02935 0.0 recB 3.1.11.5, 3.1.12.1, 3.6.4.12 L ATP-dependent helicase nuclease subunit A
APPPNAGC_02936 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
APPPNAGC_02937 2.9e-67 cheW NT chemotaxis
APPPNAGC_02938 0.0 asnB 6.3.5.4 E Asparagine synthase
APPPNAGC_02939 4.7e-48 S IDEAL
APPPNAGC_02940 5.2e-153 ykgA E Amidinotransferase
APPPNAGC_02941 3.1e-281 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APPPNAGC_02942 1.6e-89
APPPNAGC_02943 1.1e-62 ytwF P Sulfurtransferase
APPPNAGC_02944 3.3e-40
APPPNAGC_02945 8.9e-147 yjfP S COG1073 Hydrolases of the alpha beta superfamily
APPPNAGC_02946 1.8e-145 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
APPPNAGC_02947 5.1e-31 ipi S Intracellular proteinase inhibitor
APPPNAGC_02949 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
APPPNAGC_02950 4.6e-214 ywqB S zinc ion binding
APPPNAGC_02951 1.4e-107
APPPNAGC_02952 1.8e-78 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) domain
APPPNAGC_02953 3.4e-149 yitU 3.1.3.104 S hydrolases of the HAD superfamily
APPPNAGC_02954 4.8e-165 ctaG S cytochrome c oxidase
APPPNAGC_02955 3.1e-42
APPPNAGC_02956 1.6e-12
APPPNAGC_02957 1.5e-42
APPPNAGC_02958 3e-38
APPPNAGC_02959 3.3e-106 S LXG domain of WXG superfamily
APPPNAGC_02960 2.7e-37 S Pathogenicity locus
APPPNAGC_02961 3e-80 H RibD C-terminal domain
APPPNAGC_02962 3e-156 kka S Phosphotransferase enzyme family
APPPNAGC_02963 1.2e-91 yvbU K Transcriptional regulator
APPPNAGC_02964 8.2e-112 EGP Major facilitator Superfamily
APPPNAGC_02965 6.5e-171 P Periplasmic binding protein
APPPNAGC_02966 3e-137 K AraC family transcriptional regulator
APPPNAGC_02967 1.4e-184 gpr C Aldo/keto reductase family
APPPNAGC_02968 1.2e-137 bioC_2 Q Methyltransferase domain
APPPNAGC_02969 4.2e-216 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APPPNAGC_02970 2.5e-235 bglH7 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APPPNAGC_02971 2.5e-267 pts33BCA G phosphotransferase system
APPPNAGC_02972 2.1e-117 licT K transcriptional antiterminator
APPPNAGC_02973 3.8e-16 S YhfH-like protein
APPPNAGC_02975 1.4e-237 aceA 4.1.3.1 C Isocitrate lyase
APPPNAGC_02976 1e-90 T Transcriptional regulator
APPPNAGC_02977 5.2e-153 T Histidine kinase
APPPNAGC_02978 6.5e-76 nodB1 G deacetylase
APPPNAGC_02979 7.4e-269 sufB O FeS cluster assembly
APPPNAGC_02980 5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
APPPNAGC_02981 2e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APPPNAGC_02982 1e-243 O assembly protein SufD
APPPNAGC_02983 1.6e-143 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
APPPNAGC_02984 4.6e-61 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APPPNAGC_02985 4.1e-167 btuF P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
APPPNAGC_02986 6.1e-94 S Cobalamin adenosyltransferase
APPPNAGC_02987 7.2e-150 metQ P Belongs to the NlpA lipoprotein family
APPPNAGC_02988 6.5e-114 metI P COG2011 ABC-type metal ion transport system, permease component
APPPNAGC_02989 1.1e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APPPNAGC_02990 1.2e-64 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
APPPNAGC_02991 1.4e-62 arsC 1.20.4.1 P Belongs to the ArsC family
APPPNAGC_02992 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
APPPNAGC_02993 5.9e-211 fadA 2.3.1.16 I Belongs to the thiolase family
APPPNAGC_02994 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
APPPNAGC_02995 1.1e-215 EGP Major facilitator Superfamily
APPPNAGC_02996 0.0 S Sugar transport-related sRNA regulator N-term
APPPNAGC_02997 2.7e-120 S Glycosyltransferase like family
APPPNAGC_02998 4.6e-106 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
APPPNAGC_02999 1.3e-240 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APPPNAGC_03000 3e-246 S protein conserved in bacteria
APPPNAGC_03001 2.2e-58 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APPPNAGC_03002 9.6e-98
APPPNAGC_03004 5.1e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
APPPNAGC_03005 2.3e-58 mhqP S DoxX
APPPNAGC_03006 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APPPNAGC_03007 9.4e-138 est 3.1.1.1 S Carboxylesterase
APPPNAGC_03008 4.6e-137 S COG1647 Esterase lipase
APPPNAGC_03009 1.4e-176 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APPPNAGC_03010 1.2e-27 secG U Preprotein translocase subunit SecG
APPPNAGC_03011 2.1e-76 yclD
APPPNAGC_03012 9.9e-264 S Tripartite tricarboxylate transporter TctA family
APPPNAGC_03013 1.8e-73 S Tripartite tricarboxylate transporter TctB family
APPPNAGC_03014 1e-163 S Tripartite tricarboxylate transporter family receptor
APPPNAGC_03015 3e-223 4.2.1.158 M Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
APPPNAGC_03016 1.5e-264 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APPPNAGC_03017 4.7e-171 dapAf2 4.3.3.7 EM Dihydrodipicolinate synthetase family
APPPNAGC_03018 6.6e-117 MA20_15070 K FCD
APPPNAGC_03019 4.3e-239 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APPPNAGC_03020 2.1e-296 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
APPPNAGC_03021 1.4e-133 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APPPNAGC_03022 1.5e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
APPPNAGC_03023 1.3e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APPPNAGC_03024 7.9e-180 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
APPPNAGC_03025 6.1e-202 S response regulator aspartate phosphatase
APPPNAGC_03027 2.9e-38 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
APPPNAGC_03028 8.7e-235 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
APPPNAGC_03030 4.5e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APPPNAGC_03031 1.3e-14 K TetR family transcriptional regulator
APPPNAGC_03032 9.8e-128 EGP Major facilitator Superfamily
APPPNAGC_03033 1.3e-229 E Peptidase dimerisation domain
APPPNAGC_03034 3.1e-54 S Domain of unknown function (DUF4870)
APPPNAGC_03035 1.8e-213 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
APPPNAGC_03036 2.5e-107 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
APPPNAGC_03037 3.7e-168 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APPPNAGC_03038 8.7e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
APPPNAGC_03039 2.4e-37 crh G Phosphocarrier protein Chr
APPPNAGC_03040 2.7e-177 whiA K May be required for sporulation
APPPNAGC_03041 8.8e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
APPPNAGC_03042 5.2e-167 rapZ S Displays ATPase and GTPase activities
APPPNAGC_03043 4.9e-90 yvcI 3.6.1.55 F Nudix hydrolase
APPPNAGC_03044 3.8e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APPPNAGC_03045 3.8e-193 S COG0457 FOG TPR repeat
APPPNAGC_03046 3.5e-238 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
APPPNAGC_03047 1.4e-122 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
APPPNAGC_03048 7.9e-107 rhaS5 K AraC-like ligand binding domain
APPPNAGC_03049 1.2e-127 yobR 2.3.1.1 K FR47-like protein
APPPNAGC_03050 8.1e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
APPPNAGC_03051 2.6e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APPPNAGC_03052 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APPPNAGC_03053 3.6e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APPPNAGC_03054 1e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
APPPNAGC_03055 1.1e-223 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APPPNAGC_03056 9e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
APPPNAGC_03057 3.2e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
APPPNAGC_03058 1.3e-71 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
APPPNAGC_03059 1.3e-116 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
APPPNAGC_03060 8.5e-160 yvoD P COG0370 Fe2 transport system protein B
APPPNAGC_03061 9.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APPPNAGC_03062 6.2e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APPPNAGC_03063 9.3e-48 yvlD S Membrane
APPPNAGC_03064 8.8e-11 pspC KT positive regulation of macromolecule biosynthetic process
APPPNAGC_03065 3.1e-150 yvlB S Putative adhesin
APPPNAGC_03066 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APPPNAGC_03067 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APPPNAGC_03068 7.8e-169 yoaV3 EG EamA-like transporter family
APPPNAGC_03069 4.7e-200 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APPPNAGC_03070 1.8e-265 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
APPPNAGC_03071 2.2e-100 D peptidase
APPPNAGC_03072 2.3e-151 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
APPPNAGC_03073 2.7e-123 ftsE D cell division ATP-binding protein FtsE
APPPNAGC_03074 3.8e-146 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
APPPNAGC_03075 2.6e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APPPNAGC_03076 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APPPNAGC_03077 3.7e-51 yfhH S Protein of unknown function (DUF1811)
APPPNAGC_03078 2.7e-138 recX 2.4.1.337 GT4 S Modulates RecA activity
APPPNAGC_03079 1.7e-165 yfhF S nucleoside-diphosphate sugar epimerase
APPPNAGC_03080 1.2e-48
APPPNAGC_03081 9.2e-192 mccF 3.4.17.13 V LD-carboxypeptidase
APPPNAGC_03082 3.3e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APPPNAGC_03083 1.6e-61
APPPNAGC_03084 1.5e-136 3.6.3.30 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
APPPNAGC_03085 2.9e-190 afuB2 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_03086 1.5e-136 afuA P Bacterial extracellular solute-binding protein
APPPNAGC_03087 7.8e-114 surE 3.1.3.5 S Survival protein SurE
APPPNAGC_03088 1.7e-84 G Xylose isomerase-like TIM barrel
APPPNAGC_03089 1.6e-70 ywgB K Transcriptional regulator
APPPNAGC_03090 3.5e-163 ahpF 1.8.1.9 O Pyridine nucleotide-disulphide oxidoreductase
APPPNAGC_03092 3.6e-148 pdaA G deacetylase
APPPNAGC_03093 8.5e-140 S Domain of unknown function (DUF368)
APPPNAGC_03094 3.4e-242 yhdP S COG1253 Hemolysins and related proteins containing CBS domains
APPPNAGC_03095 5.7e-115 gpmB 5.4.2.11 G Belongs to the phosphoglycerate mutase family
APPPNAGC_03096 8.8e-217 yfkA S YfkB-like domain
APPPNAGC_03097 1e-145 yfkD S YfkD-like protein
APPPNAGC_03100 2.2e-21 S Fur-regulated basic protein B
APPPNAGC_03101 1.1e-245 cydA 1.10.3.14 C oxidase, subunit
APPPNAGC_03102 8.1e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
APPPNAGC_03103 2.1e-106
APPPNAGC_03104 0.0 pepF2 E COG1164 Oligoendopeptidase F
APPPNAGC_03105 9.1e-294 katB 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
APPPNAGC_03108 2.6e-244 iucD_1 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
APPPNAGC_03109 4.4e-242 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
APPPNAGC_03110 7.9e-111 rnhA 3.1.26.4 L Caulimovirus viroplasmin
APPPNAGC_03111 1.4e-40
APPPNAGC_03112 2.2e-45 abrB K SpoVT / AbrB like domain
APPPNAGC_03113 1e-56
APPPNAGC_03114 1.9e-232 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APPPNAGC_03115 3.2e-181 mreB D Rod-share determining protein MreBH
APPPNAGC_03116 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
APPPNAGC_03117 9.4e-164 fruB 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
APPPNAGC_03118 1.9e-133 fruR K Transcriptional regulator
APPPNAGC_03119 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APPPNAGC_03120 4.8e-207 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
APPPNAGC_03121 7.8e-85 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
APPPNAGC_03122 2e-121 treR K transcriptional
APPPNAGC_03123 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
APPPNAGC_03124 1.7e-265 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APPPNAGC_03125 0.0 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
APPPNAGC_03126 1.6e-301 yngK T Glycosyl hydrolase-like 10
APPPNAGC_03127 7.3e-234 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APPPNAGC_03128 6e-239 agcS E Sodium alanine symporter
APPPNAGC_03129 6.1e-94 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
APPPNAGC_03130 9.2e-311 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
APPPNAGC_03131 8.7e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APPPNAGC_03132 5.1e-229 pilS 2.7.13.3 T Histidine kinase
APPPNAGC_03133 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
APPPNAGC_03134 2.3e-304 yfiB3 V ABC transporter
APPPNAGC_03135 0.0 uvrD 3.6.4.12 L DNA helicase
APPPNAGC_03136 4.5e-169 phnD P Phosphonate ABC transporter
APPPNAGC_03137 9.1e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
APPPNAGC_03138 2.4e-136 phnE 3.6.1.63 P ABC transporter
APPPNAGC_03139 3e-142 phnE 3.6.1.63 P ABC transporter
APPPNAGC_03140 3.8e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APPPNAGC_03141 5.7e-242 matE V MatE
APPPNAGC_03142 2.4e-104 tetR K Bacterial regulatory proteins, tetR family
APPPNAGC_03143 9.4e-64 gpm5 3.1.3.3, 5.4.2.11 G alpha-ribazole phosphatase activity
APPPNAGC_03144 2e-157 3.4.11.5 I Alpha/beta hydrolase family
APPPNAGC_03145 1.5e-158 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_03146 1.7e-182 dppB EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_03147 6.6e-301 E COG0747 ABC-type dipeptide transport system, periplasmic component
APPPNAGC_03148 7.3e-186 appF E Belongs to the ABC transporter superfamily
APPPNAGC_03149 3.7e-182 dppD P Belongs to the ABC transporter superfamily
APPPNAGC_03150 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
APPPNAGC_03151 3.9e-57 XK27_04860 S Domain of unknown function (DUF4440)
APPPNAGC_03152 1.5e-88 ynaD J Acetyltransferase (GNAT) domain
APPPNAGC_03153 2.1e-227 S Sulphur transport
APPPNAGC_03154 1.5e-175 S transport system, periplasmic component
APPPNAGC_03155 1.9e-170 S Belongs to the binding-protein-dependent transport system permease family
APPPNAGC_03156 1e-137 S transport system, ATPase component
APPPNAGC_03157 9.2e-181
APPPNAGC_03158 2e-197 cysA 3.6.3.25, 3.6.3.29 P Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
APPPNAGC_03159 1.5e-133 cysW P COG4208 ABC-type sulfate transport system, permease component
APPPNAGC_03160 8.5e-132 cysT O COG0555 ABC-type sulfate transport system, permease component
APPPNAGC_03161 5.9e-191 sbp P COG1613 ABC-type sulfate transport system, periplasmic component
APPPNAGC_03162 1.3e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APPPNAGC_03163 1.8e-295 T COG0642 Signal transduction histidine kinase
APPPNAGC_03164 9.9e-258 dld 1.1.1.303, 1.1.1.4, 1.1.2.4, 1.1.3.15 C Glycolate oxidase subunit
APPPNAGC_03165 3.8e-155 yocS S -transporter
APPPNAGC_03166 1.2e-239 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
APPPNAGC_03167 7.7e-155 nhaR K LysR substrate binding domain
APPPNAGC_03168 3.1e-295 E COG0747 ABC-type dipeptide transport system, periplasmic component
APPPNAGC_03169 3.3e-205 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
APPPNAGC_03170 3.8e-64 K Helix-turn-helix XRE-family like proteins
APPPNAGC_03171 4.6e-94 2.3.1.128 J Acetyltransferase (GNAT) domain
APPPNAGC_03172 1.1e-150 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_03173 4.4e-169 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_03174 3.2e-269 G Bacterial extracellular solute-binding protein
APPPNAGC_03175 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
APPPNAGC_03176 1.3e-168 yisR1 K AraC-like ligand binding domain
APPPNAGC_03177 2.2e-120 mutF V ABC transporter, ATP-binding protein
APPPNAGC_03178 1.3e-118 spaE S ABC-2 family transporter protein
APPPNAGC_03179 1.8e-128 mutG S ABC-2 family transporter protein
APPPNAGC_03180 2.1e-120 K Transcriptional regulatory protein, C terminal
APPPNAGC_03181 1.2e-250 T His Kinase A (phosphoacceptor) domain
APPPNAGC_03182 2.1e-73 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APPPNAGC_03183 7.2e-74 lrpC K helix_turn_helix ASNC type
APPPNAGC_03184 1.5e-101 argO S Lysine exporter protein LysE YggA
APPPNAGC_03185 3.8e-273 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APPPNAGC_03186 1.1e-92 ykkA S Protein of unknown function (DUF664)
APPPNAGC_03187 1.3e-72 yuxK S protein conserved in bacteria
APPPNAGC_03188 2.9e-81 S Protein of unknown function (DUF1569)
APPPNAGC_03192 4.7e-87 ydcK S Belongs to the SprT family
APPPNAGC_03193 3.9e-08
APPPNAGC_03194 0.0 yhgF K COG2183 Transcriptional accessory protein
APPPNAGC_03195 1e-113 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
APPPNAGC_03196 9.6e-141 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APPPNAGC_03197 1.1e-81 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
APPPNAGC_03198 3.2e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
APPPNAGC_03199 9e-184 rsbU 3.1.3.3 KT phosphatase
APPPNAGC_03200 8e-73 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
APPPNAGC_03201 1.3e-52 rsbS T antagonist
APPPNAGC_03202 5.8e-141 rsbR T Positive regulator of sigma-B
APPPNAGC_03203 1.3e-55 ndoA L Toxic component of a toxin-antitoxin (TA) module
APPPNAGC_03204 8e-25 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
APPPNAGC_03205 2.9e-224 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APPPNAGC_03206 9.7e-186 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
APPPNAGC_03207 7.8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APPPNAGC_03208 1.4e-128 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
APPPNAGC_03209 5.7e-101 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
APPPNAGC_03210 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APPPNAGC_03211 5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
APPPNAGC_03212 3.2e-47
APPPNAGC_03213 2.8e-106 S Integral membrane protein
APPPNAGC_03214 1.4e-212 S Winged helix DNA-binding domain
APPPNAGC_03215 1.2e-137 G Xylose isomerase-like TIM barrel
APPPNAGC_03216 2.5e-189 S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_03217 1.1e-191 G Xylose isomerase
APPPNAGC_03218 3.5e-157 S electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
APPPNAGC_03219 1.2e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
APPPNAGC_03220 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APPPNAGC_03221 3.7e-85 mrpE P Na+/H+ ion antiporter subunit
APPPNAGC_03222 1.6e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APPPNAGC_03223 4.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APPPNAGC_03224 5.1e-64 mnhB2 P antiporter activity
APPPNAGC_03225 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
APPPNAGC_03226 5.1e-130 T PhoQ Sensor
APPPNAGC_03227 8.7e-110 S Nitroreductase family
APPPNAGC_03228 2e-58 hxlR K transcriptional
APPPNAGC_03229 1.2e-180 ykfD E Belongs to the ABC transporter superfamily
APPPNAGC_03230 9.9e-166 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
APPPNAGC_03231 1.3e-173 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
APPPNAGC_03232 0.0 dppE E ABC transporter substrate-binding protein
APPPNAGC_03233 7.5e-183 dppD P Belongs to the ABC transporter superfamily
APPPNAGC_03234 3.3e-172 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_03235 4e-162 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_03236 1.2e-149 dppA E D-aminopeptidase
APPPNAGC_03237 4.8e-152 rarD S -transporter
APPPNAGC_03238 3e-198 pgl 3.1.1.31 G 6-phosphogluconolactonase
APPPNAGC_03239 4.3e-195 ald 1.4.1.1 E Belongs to the AlaDH PNT family
APPPNAGC_03240 2.5e-212 QT Transcriptional regulator
APPPNAGC_03241 2e-157 sseA 2.8.1.1, 2.8.1.2 P sulfurtransferase
APPPNAGC_03242 2.7e-247 yeeF E Amino acid permease
APPPNAGC_03243 1.9e-104 cwlK M Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin
APPPNAGC_03244 3.4e-233 K Helix-turn-helix XRE-family like proteins
APPPNAGC_03245 2.1e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
APPPNAGC_03247 1.3e-224 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APPPNAGC_03248 3.6e-168 yfhM S Alpha beta hydrolase
APPPNAGC_03249 1.9e-139 P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
APPPNAGC_03250 5.3e-176 S Phosphotransferase system, EIIC
APPPNAGC_03251 1.2e-131 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APPPNAGC_03252 8.8e-90 tag 3.2.2.20 L Methyladenine glycosylase
APPPNAGC_03253 3.2e-127
APPPNAGC_03254 6.1e-91 3.4.21.89 U Signal peptidase
APPPNAGC_03255 0.0 vpr O Belongs to the peptidase S8 family
APPPNAGC_03256 4.3e-152 hisJ3 3.1.3.15 E PHP domain
APPPNAGC_03257 1.1e-184 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
APPPNAGC_03258 6.8e-113 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APPPNAGC_03259 7.9e-119
APPPNAGC_03260 1.2e-194 yetN S Protein of unknown function (DUF3900)
APPPNAGC_03261 5.1e-185 cdaR KT Sugar diacid utilization regulator
APPPNAGC_03262 2.2e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
APPPNAGC_03263 7.1e-80 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
APPPNAGC_03264 9.6e-146 map 3.4.11.18 E Methionine aminopeptidase
APPPNAGC_03265 1.6e-79 yvbK 3.1.3.25 K acetyltransferase
APPPNAGC_03266 2.4e-242 aspT EK Alanine-glyoxylate amino-transferase
APPPNAGC_03267 1e-87 3.1.1.29 K -acetyltransferase
APPPNAGC_03268 3e-54
APPPNAGC_03269 1.9e-74 K transcriptional
APPPNAGC_03270 8.1e-188 mgtE P Acts as a magnesium transporter
APPPNAGC_03271 3.4e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APPPNAGC_03272 5.4e-193 desK 2.7.13.3 T Histidine kinase
APPPNAGC_03273 1.1e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
APPPNAGC_03274 3.6e-168 agpT K AraC-like ligand binding domain
APPPNAGC_03275 1.6e-249 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
APPPNAGC_03276 1.2e-108 dedA 3.1.3.1 S SNARE associated Golgi protein
APPPNAGC_03277 2.7e-100 yvrI K RNA polymerase
APPPNAGC_03278 3.7e-38
APPPNAGC_03279 4.6e-160 U Binding-protein-dependent transport system inner membrane component
APPPNAGC_03280 2.6e-172 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_03281 2e-222 T cheY-homologous receiver domain
APPPNAGC_03282 7e-306 2.7.13.3 T Histidine kinase
APPPNAGC_03283 0.0 G Bacterial extracellular solute-binding protein
APPPNAGC_03284 6.4e-123 ywiC S YwiC-like protein
APPPNAGC_03285 4.5e-272 narK P COG2223 Nitrate nitrite transporter
APPPNAGC_03286 1.3e-111 nreC T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APPPNAGC_03287 2.6e-197 nreB 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
APPPNAGC_03288 1.9e-83 ptsP 2.7.13.3, 2.7.3.9 T phosphoenolpyruvate-protein phosphotransferase activity
APPPNAGC_03289 1.7e-125 narI 1.7.5.1 C nitrate reductase, gamma subunit
APPPNAGC_03290 4.6e-114 narJ C Nitrate reductase delta subunit
APPPNAGC_03291 0.0 narH 1.7.5.1 C Nitrate reductase, beta
APPPNAGC_03292 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APPPNAGC_03293 5.4e-79 scdA D Di-iron-containing protein involved in the repair of iron-sulfur clusters
APPPNAGC_03294 4.4e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
APPPNAGC_03295 1.7e-282 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APPPNAGC_03296 1e-114 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
APPPNAGC_03297 1.4e-139 K Helix-turn-helix domain, rpiR family
APPPNAGC_03298 6.7e-87 K Transcriptional regulator PadR-like family
APPPNAGC_03299 0.0 Q FtsX-like permease family
APPPNAGC_03300 3.8e-128 lolD-2 V COG1136 ABC-type antimicrobial peptide transport system, ATPase component
APPPNAGC_03303 1.3e-196 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
APPPNAGC_03304 3.3e-133 potC3 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_03305 3.6e-138 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
APPPNAGC_03306 1.3e-165 iunH3 3.2.2.1 F nucleoside hydrolase
APPPNAGC_03307 1.7e-193 potD2 E COG0687 Spermidine putrescine-binding periplasmic protein
APPPNAGC_03308 2.4e-56
APPPNAGC_03309 1.1e-47
APPPNAGC_03311 2.7e-160 T Belongs to the universal stress protein A family
APPPNAGC_03312 2.2e-140 rpl K Helix-turn-helix domain, rpiR family
APPPNAGC_03313 7.5e-170 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
APPPNAGC_03314 4.4e-229 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
APPPNAGC_03315 9.9e-74 fruD 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
APPPNAGC_03316 3.7e-154 kbaY 4.1.2.13, 4.1.2.40 G in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
APPPNAGC_03317 8.8e-67
APPPNAGC_03318 4.7e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
APPPNAGC_03321 1.4e-69 fabH 2.3.1.180 I Chalcone and stilbene synthases, N-terminal domain
APPPNAGC_03322 4.6e-115 K Transcriptional regulator
APPPNAGC_03323 5.8e-195 V COG0842 ABC-type multidrug transport system, permease component
APPPNAGC_03324 1.5e-138 V COG1131 ABC-type multidrug transport system, ATPase component
APPPNAGC_03325 6.9e-80 M PFAM secretion protein HlyD family protein
APPPNAGC_03327 1.8e-204 MA20_04465 4.2.3.1 E Pyridoxal-phosphate dependent enzyme
APPPNAGC_03328 6.9e-139 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
APPPNAGC_03329 5.6e-239 KT transcriptional regulatory protein
APPPNAGC_03330 2e-261 abgB 3.5.1.47 S amidohydrolase
APPPNAGC_03331 9.6e-278 abgT H AbgT putative transporter family
APPPNAGC_03332 2.2e-235 3.5.1.47 S Peptidase dimerisation domain
APPPNAGC_03334 2.5e-23 C 4Fe-4S binding domain
APPPNAGC_03335 5.7e-39 S Protein of unknown function (DUF1450)
APPPNAGC_03336 6.7e-113 sodA 1.15.1.1 P Iron/manganese superoxide dismutases, C-terminal domain
APPPNAGC_03337 4.4e-115 sufR K Transcriptional regulator
APPPNAGC_03338 1.4e-249 S Polysaccharide biosynthesis protein
APPPNAGC_03339 1.4e-147 exoM S Glycosyl transferase family 2
APPPNAGC_03340 1.8e-193 M Glycosyl transferases group 1
APPPNAGC_03341 1.5e-53
APPPNAGC_03342 4.4e-229 M -O-antigen
APPPNAGC_03343 3e-251 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APPPNAGC_03344 7.3e-68
APPPNAGC_03345 2.1e-137 tuaG GT2 M Glycosyltransferase like family 2
APPPNAGC_03346 2.5e-171 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
APPPNAGC_03347 8.1e-174 S Oxidoreductase family, NAD-binding Rossmann fold
APPPNAGC_03350 1.1e-17
APPPNAGC_03353 7.6e-211 UW nuclease activity
APPPNAGC_03362 2.8e-91 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APPPNAGC_03363 1.9e-104 adaA 3.2.2.21 K Transcriptional regulator
APPPNAGC_03364 1.8e-167 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
APPPNAGC_03365 1.4e-209 S Oxidoreductase family, NAD-binding Rossmann fold
APPPNAGC_03366 7e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APPPNAGC_03367 2.6e-149 yidA S hydrolases of the HAD superfamily
APPPNAGC_03368 7.8e-88 S DinB family
APPPNAGC_03369 1.8e-162 K WYL domain
APPPNAGC_03370 1.5e-100 S Bacteriocin-protection, YdeI or OmpD-Associated
APPPNAGC_03371 8.8e-125 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
APPPNAGC_03372 1.4e-184 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APPPNAGC_03374 6.4e-114 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APPPNAGC_03375 1.2e-202 yhcY 2.7.13.3 T Histidine kinase
APPPNAGC_03376 1e-37
APPPNAGC_03378 3.4e-112 KLT serine threonine protein kinase
APPPNAGC_03379 5.7e-86 K Transcriptional regulator
APPPNAGC_03380 5.7e-140 3.1.26.11 S Metallo-beta-lactamase superfamily
APPPNAGC_03381 3e-108 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
APPPNAGC_03383 6.8e-13
APPPNAGC_03384 7.6e-133
APPPNAGC_03385 7.4e-121 yhcG V ABC transporter, ATP-binding protein
APPPNAGC_03386 2.4e-60 K helix_turn_helix gluconate operon transcriptional repressor
APPPNAGC_03388 1.3e-127
APPPNAGC_03389 2.9e-159 S NYN domain
APPPNAGC_03390 4.6e-49 K sequence-specific DNA binding
APPPNAGC_03391 1.1e-20 K sequence-specific DNA binding
APPPNAGC_03392 2.5e-273 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
APPPNAGC_03393 9e-240 G Bacterial extracellular solute-binding protein
APPPNAGC_03394 3.3e-161 araP G Binding-protein-dependent transport system inner membrane component
APPPNAGC_03395 2.4e-156 araQ P Binding-protein-dependent transport system inner membrane component
APPPNAGC_03396 1.8e-201 msmX E ABC transporter
APPPNAGC_03397 6.7e-98
APPPNAGC_03398 3.1e-181 scrR K transcriptional
APPPNAGC_03399 4.3e-175 lplB7 G COG4209 ABC-type polysaccharide transport system, permease component
APPPNAGC_03400 1.5e-161 lplC7 G COG0395 ABC-type sugar transport system, permease component
APPPNAGC_03401 0.0 lplA5 G Bacterial extracellular solute-binding protein
APPPNAGC_03402 0.0 sacC 3.2.1.26, 3.2.1.80 GH32 G invertase
APPPNAGC_03403 3e-292 cscA 3.2.1.26, 3.2.1.80 GH32 G invertase
APPPNAGC_03404 2.3e-128 IQ Enoyl-(Acyl carrier protein) reductase
APPPNAGC_03405 1.1e-213 yaaH M Glycoside Hydrolase Family
APPPNAGC_03406 2.3e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
APPPNAGC_03407 1.1e-286 uxaA 4.2.1.7 G Altronate
APPPNAGC_03408 1.4e-253 yteT S Oxidoreductase family, C-terminal alpha/beta domain
APPPNAGC_03409 1.5e-121 S Integral membrane protein
APPPNAGC_03410 2.1e-77 G carbohydrate transport
APPPNAGC_03411 5.4e-222 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APPPNAGC_03412 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
APPPNAGC_03413 3e-165 E Abhydrolase family
APPPNAGC_03414 1.3e-143 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_03415 5.7e-180 G COG4209 ABC-type polysaccharide transport system, permease component
APPPNAGC_03416 1.7e-295 G ABC transporter substrate-binding protein
APPPNAGC_03417 0.0 K Transcriptional regulator
APPPNAGC_03418 1.6e-157 3.2.2.21 K AraC-like ligand binding domain
APPPNAGC_03419 6.4e-193 pelE 3.4.11.10, 3.4.11.6, 4.2.2.2 M Pectic acid lyase
APPPNAGC_03420 7.9e-103 J Acetyltransferase (GNAT) domain
APPPNAGC_03421 3e-128 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
APPPNAGC_03422 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
APPPNAGC_03423 0.0 lplA7 G Bacterial extracellular solute-binding protein
APPPNAGC_03424 3.7e-168 lplC1 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_03425 1.1e-173 lplB P Binding-protein-dependent transport system inner membrane component
APPPNAGC_03426 2.9e-271 araC7 T helix_turn_helix, arabinose operon control protein
APPPNAGC_03427 0.0 2.7.13.3 T Histidine kinase
APPPNAGC_03428 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
APPPNAGC_03429 1.4e-202 glcP G Major Facilitator Superfamily
APPPNAGC_03430 3.3e-178 xylR3 2.7.1.2 GK ROK family
APPPNAGC_03431 1e-276 M1-1044 S Belongs to the UPF0061 (SELO) family
APPPNAGC_03432 3.9e-73 S DinB superfamily
APPPNAGC_03433 3.2e-161 Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
APPPNAGC_03434 2.2e-15 ygaJ E Belongs to the peptidase S51 family
APPPNAGC_03435 1.3e-66 ygaJ E Belongs to the peptidase S51 family
APPPNAGC_03436 5.3e-158 S Alpha beta hydrolase
APPPNAGC_03438 6.5e-51 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
APPPNAGC_03439 2.2e-93 6.2.1.3 H Aldolase/RraA
APPPNAGC_03440 6.8e-139 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APPPNAGC_03441 3.5e-132 P Sodium:sulfate symporter transmembrane region
APPPNAGC_03442 2.2e-131 K Transcriptional regulator
APPPNAGC_03443 5.5e-18 dcd 3.5.4.13 F 2'-deoxycytidine 5'-triphosphate deaminase (DCD)
APPPNAGC_03444 2e-148 P COG0370 Fe2 transport system protein B
APPPNAGC_03445 4.4e-164 yjiA S Cobalamin biosynthesis protein CobW
APPPNAGC_03446 5.1e-179 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
APPPNAGC_03447 1.4e-231 adcA P Zinc-uptake complex component A periplasmic
APPPNAGC_03448 1.5e-124 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
APPPNAGC_03449 1.5e-128 adcB P ABC 3 transport family
APPPNAGC_03450 5.7e-264 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APPPNAGC_03451 6.4e-165 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
APPPNAGC_03452 3.4e-163 MA20_14845 4.2.1.141 S Fumarylacetoacetate (FAA) hydrolase family
APPPNAGC_03453 4.7e-140 K helix_turn_helix isocitrate lyase regulation
APPPNAGC_03454 0.0 yjhG 4.2.1.82 EG Dehydratase family
APPPNAGC_03455 5.9e-237 yjhF EG COG2610 H gluconate symporter and related permeases
APPPNAGC_03456 4.5e-30 K MerR family transcriptional regulator
APPPNAGC_03457 2.9e-134 IQ Enoyl-(Acyl carrier protein) reductase
APPPNAGC_03458 3.8e-97
APPPNAGC_03459 1.9e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APPPNAGC_03460 4.4e-77 fld C Flavodoxin
APPPNAGC_03461 1.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
APPPNAGC_03462 6.6e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APPPNAGC_03463 1e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APPPNAGC_03464 3e-44 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APPPNAGC_03465 4.9e-87 yizA S DinB family
APPPNAGC_03466 3.1e-173
APPPNAGC_03468 3.4e-156 yufQ S Belongs to the binding-protein-dependent transport system permease family
APPPNAGC_03469 2.6e-189 yufP S Belongs to the binding-protein-dependent transport system permease family
APPPNAGC_03470 7.8e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
APPPNAGC_03471 3.2e-203 bmpA S ABC-type transport system, periplasmic component surface lipoprotein
APPPNAGC_03472 1.3e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
APPPNAGC_03473 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APPPNAGC_03474 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
APPPNAGC_03475 5.7e-121 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
APPPNAGC_03477 5.7e-152 fhuC 3.6.3.34 HP ABC transporter
APPPNAGC_03478 6.3e-169 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPPNAGC_03479 3.2e-176 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APPPNAGC_03481 2e-27 mepA V MATE efflux family protein
APPPNAGC_03482 4.8e-165 lacX G Aldose 1-epimerase
APPPNAGC_03483 0.0 acyII 3.5.1.11, 3.5.1.97 S Penicillin amidase
APPPNAGC_03484 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
APPPNAGC_03486 2.4e-38 K Helix-turn-helix domain
APPPNAGC_03488 6.7e-110 S Chlorophyllase
APPPNAGC_03489 2.2e-92 S Chlorophyllase
APPPNAGC_03490 4.4e-94 yfiN V ABC-type multidrug transport system, permease component
APPPNAGC_03491 6.1e-85 yfiM V ABC-2 type transporter
APPPNAGC_03492 7e-114 yfiL V ABC transporter, ATP-binding protein
APPPNAGC_03493 9.7e-70 T Histidine kinase
APPPNAGC_03494 1.8e-76 yfiK K Regulator
APPPNAGC_03495 1.8e-147 S Alpha beta hydrolase
APPPNAGC_03496 1.2e-78 K Helix-turn-helix domain
APPPNAGC_03497 3.4e-08
APPPNAGC_03498 6.5e-112 L DNA alkylation repair enzyme
APPPNAGC_03499 7.7e-134 IQ Enoyl-(Acyl carrier protein) reductase
APPPNAGC_03501 5.9e-61 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APPPNAGC_03502 8.8e-10 fur P Ferric uptake regulator family
APPPNAGC_03503 5.8e-215 V ABC transporter
APPPNAGC_03504 2.1e-223 V ABC transporter
APPPNAGC_03505 1.5e-226 V ABC transporter transmembrane region
APPPNAGC_03506 1.4e-222 V ABC transporter transmembrane region
APPPNAGC_03507 9.5e-212 E ABC transporter substrate-binding protein
APPPNAGC_03508 5.3e-94 nikV 3.6.3.24 E abc transporter atp-binding protein
APPPNAGC_03509 2.9e-89 oppD 3.6.3.24 EP ABC-type dipeptide oligopeptide nickel transport system, ATPase component
APPPNAGC_03510 2e-101 nikC P With NikABDE is involved in nickel transport into the cell
APPPNAGC_03511 3.1e-101 nikB EP Binding-protein-dependent transport system inner membrane component
APPPNAGC_03512 9.7e-48 K MarR family
APPPNAGC_03513 9.4e-90 C aldo keto reductase
APPPNAGC_03514 1.3e-29 rmeD K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
APPPNAGC_03515 2.4e-59 K Bacterial regulatory proteins, tetR family
APPPNAGC_03516 1.8e-51 K Acetyltransferase (GNAT) domain
APPPNAGC_03517 1e-41 ydzF K HxlR-like helix-turn-helix
APPPNAGC_03518 8.4e-173 rocF 3.5.3.1, 3.5.3.11 E Arginase family
APPPNAGC_03519 3.9e-112 K helix_turn_helix, mercury resistance
APPPNAGC_03520 4.6e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
APPPNAGC_03521 1e-110 V ABC-2 type transporter
APPPNAGC_03522 6.5e-71 EGP Major facilitator Superfamily
APPPNAGC_03523 5.9e-103 qacR K TetR family transcriptional regulator
APPPNAGC_03524 3.9e-129 pldB 3.1.1.5 I Alpha beta hydrolase
APPPNAGC_03525 4.6e-94 K Winged helix DNA-binding domain
APPPNAGC_03526 1.6e-55 ccpA K helix_turn _helix lactose operon repressor
APPPNAGC_03527 1.3e-191 scrB 3.2.1.26 GH32 G invertase
APPPNAGC_03528 1.2e-178 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
APPPNAGC_03529 2.8e-69 yhfA S Haloacid dehalogenase-like hydrolase
APPPNAGC_03530 3.6e-126 4.1.2.14 S KDGP aldolase
APPPNAGC_03531 1.3e-199 selA 2.9.1.1, 4.3.1.29 E L-seryl-tRNA selenium transferase
APPPNAGC_03532 1.9e-113 S Domain of unknown function (DUF4310)
APPPNAGC_03533 6.2e-140 S Domain of unknown function (DUF4311)
APPPNAGC_03534 1.6e-55 S Domain of unknown function (DUF4312)
APPPNAGC_03535 2.6e-61 S Glycine-rich SFCGS
APPPNAGC_03536 2.1e-46 S PRD domain
APPPNAGC_03537 2.9e-210 dho 3.5.2.3 S amidohydrolase
APPPNAGC_03538 0.0 K Mga helix-turn-helix domain
APPPNAGC_03539 0.0 pbg 3.2.1.23 G beta-galactosidase
APPPNAGC_03540 7.5e-160 K AraC-like ligand binding domain
APPPNAGC_03541 1.6e-147 cypA Q Cytochrome P450
APPPNAGC_03542 6.2e-131 EGP PFAM major facilitator superfamily MFS_1
APPPNAGC_03543 1.2e-56 K Bacterial regulatory proteins, tetR family
APPPNAGC_03544 1.8e-38 2.3.1.60 K FR47-like protein
APPPNAGC_03545 6.2e-125 S Nucleotidyltransferase domain
APPPNAGC_03546 5.8e-131 IQ Enoyl-(Acyl carrier protein) reductase
APPPNAGC_03547 2.3e-43 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APPPNAGC_03548 9.2e-240 pbpE V Beta-lactamase
APPPNAGC_03549 1.9e-120 K helix_turn_helix, mercury resistance
APPPNAGC_03550 2.8e-88 2.7.1.48, 3.1.3.18 F uridine kinase
APPPNAGC_03551 8.4e-35 ble E lactoylglutathione lyase activity
APPPNAGC_03552 1.7e-19 M Host cell surface-exposed lipoprotein
APPPNAGC_03553 1.9e-104 K Bacterial transcriptional repressor C-terminal
APPPNAGC_03554 3.1e-245 npr 1.11.1.1 P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
APPPNAGC_03555 1.3e-132 S Belongs to the short-chain dehydrogenases reductases (SDR) family
APPPNAGC_03556 9.7e-155 K DNA-binding protein
APPPNAGC_03557 4.6e-232 eph 3.3.2.9 S Epoxide hydrolase
APPPNAGC_03558 3.4e-200 S thiolester hydrolase activity
APPPNAGC_03559 2e-77 yvmB1 K helix_turn_helix multiple antibiotic resistance protein
APPPNAGC_03560 5.7e-65 J oxidation-reduction process
APPPNAGC_03561 9.3e-278 yhjG CH FAD binding domain
APPPNAGC_03562 5.3e-49 ybcL EGP Major facilitator Superfamily
APPPNAGC_03563 1.3e-138 ybcL EGP Major facilitator Superfamily
APPPNAGC_03564 2.6e-48 ybzH K ArsR family transcriptional regulator
APPPNAGC_03565 2.2e-39 yxcB K Transcriptional regulator C-terminal region
APPPNAGC_03566 2.3e-37 S Protein of unknown function (DUF3021)
APPPNAGC_03568 0.0 yobO M Pectate lyase superfamily protein
APPPNAGC_03576 1.5e-07
APPPNAGC_03584 2.3e-235 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
APPPNAGC_03585 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
APPPNAGC_03586 9.6e-55 nirD 1.7.1.15 P Nitrite reductase
APPPNAGC_03587 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
APPPNAGC_03588 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APPPNAGC_03589 1.4e-220 nasA P COG2223 Nitrate nitrite transporter
APPPNAGC_03590 1.8e-258 M Belongs to the BCCT transporter (TC 2.A.15) family
APPPNAGC_03592 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
APPPNAGC_03593 1.4e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APPPNAGC_03594 1e-61 phaG P Na+/H+ antiporter subunit
APPPNAGC_03595 3.1e-38 phaF P Multiple resistance and pH regulation protein F (MrpF / PhaF)
APPPNAGC_03596 1.1e-81 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APPPNAGC_03597 2e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APPPNAGC_03598 5.2e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APPPNAGC_03599 2.2e-70 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APPPNAGC_03600 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
APPPNAGC_03602 6.2e-96 yqeG S hydrolase of the HAD superfamily
APPPNAGC_03603 3.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
APPPNAGC_03604 9.4e-147 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APPPNAGC_03605 2e-46 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
APPPNAGC_03606 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APPPNAGC_03607 6.7e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
APPPNAGC_03608 9.8e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APPPNAGC_03609 2.5e-158 cvfB S protein conserved in bacteria
APPPNAGC_03610 1.8e-133 cmoA S Methyltransferase domain
APPPNAGC_03611 3e-145 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APPPNAGC_03612 2.9e-100 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
APPPNAGC_03613 5.2e-107 comEB 3.5.4.12 F ComE operon protein 2
APPPNAGC_03614 0.0 comEC S Competence protein ComEC
APPPNAGC_03615 2.4e-07 S YqzM-like protein
APPPNAGC_03616 3.1e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
APPPNAGC_03617 4.8e-36 rpsT J Binds directly to 16S ribosomal RNA
APPPNAGC_03618 9.3e-206 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
APPPNAGC_03619 1.7e-194 spoIIP M stage II sporulation protein P
APPPNAGC_03620 1.7e-52
APPPNAGC_03621 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APPPNAGC_03622 1.7e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
APPPNAGC_03623 2e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APPPNAGC_03624 4.2e-69 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APPPNAGC_03625 5.1e-294 dnaK O Heat shock 70 kDa protein
APPPNAGC_03626 2.8e-194 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APPPNAGC_03627 9.1e-170 prmA J Methylates ribosomal protein L11
APPPNAGC_03628 1.6e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APPPNAGC_03629 2.4e-253 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
APPPNAGC_03630 3.2e-133 ycgJ_1 Q ubiE/COQ5 methyltransferase family
APPPNAGC_03631 6.7e-221 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APPPNAGC_03632 1.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APPPNAGC_03633 2.1e-171 iolS C Aldo keto reductase
APPPNAGC_03634 9.2e-159 yqeW P COG1283 Na phosphate symporter
APPPNAGC_03635 2.1e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
APPPNAGC_03636 5.2e-54 yqeY S Yqey-like protein
APPPNAGC_03637 9.5e-221 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
APPPNAGC_03638 6e-95 yqfA S UPF0365 protein
APPPNAGC_03639 3.9e-43
APPPNAGC_03640 6.7e-47 yqfC S sporulation protein YqfC
APPPNAGC_03641 1.3e-218 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
APPPNAGC_03642 5.8e-172 phoH T Phosphate starvation-inducible protein PhoH
APPPNAGC_03643 0.0 yqfF S membrane-associated HD superfamily hydrolase
APPPNAGC_03644 1.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APPPNAGC_03645 6.3e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
APPPNAGC_03646 1.6e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
APPPNAGC_03647 2.4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APPPNAGC_03648 7.1e-18 S YqzL-like protein
APPPNAGC_03649 9.7e-138 recO L Involved in DNA repair and RecF pathway recombination
APPPNAGC_03651 9.1e-172 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
APPPNAGC_03652 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
APPPNAGC_03653 3.8e-111 ccpN K CBS domain
APPPNAGC_03654 1.6e-143 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
APPPNAGC_03655 1.4e-78 yaiI S Belongs to the UPF0178 family
APPPNAGC_03656 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APPPNAGC_03657 1.9e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APPPNAGC_03658 1.8e-63 C COG2010 Cytochrome c, mono- and diheme variants
APPPNAGC_03659 7.8e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
APPPNAGC_03660 3.5e-189 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APPPNAGC_03661 2e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
APPPNAGC_03662 1.5e-83 carD K Transcription factor
APPPNAGC_03663 3.1e-44 yqfQ S YqfQ-like protein
APPPNAGC_03664 7.5e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APPPNAGC_03665 2e-163 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
APPPNAGC_03666 3.6e-07 yqfT S Protein of unknown function (DUF2624)
APPPNAGC_03667 1.8e-212 pilS 2.7.13.3 T His Kinase A (phosphoacceptor) domain
APPPNAGC_03668 5.3e-130 GH23 M Transglycosylase SLT domain
APPPNAGC_03669 1.7e-142 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
APPPNAGC_03670 3.1e-132 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
APPPNAGC_03671 7.5e-76 zur P Belongs to the Fur family
APPPNAGC_03673 1.4e-57
APPPNAGC_03674 1.4e-74 yqiW S Belongs to the UPF0403 family
APPPNAGC_03675 1.4e-221 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APPPNAGC_03676 6.9e-181 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APPPNAGC_03677 1.6e-185 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APPPNAGC_03678 5e-257 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APPPNAGC_03679 1.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
APPPNAGC_03680 0.0 bkdR KT Transcriptional regulator
APPPNAGC_03681 1e-34 yqzF S Protein of unknown function (DUF2627)
APPPNAGC_03682 1.5e-106 2.7.8.33, 2.7.8.35 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APPPNAGC_03683 1.8e-142 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
APPPNAGC_03684 1.5e-236 rseP 3.4.21.116 M Stage IV sporulation protein B
APPPNAGC_03685 6.4e-291 recN L May be involved in recombinational repair of damaged DNA
APPPNAGC_03686 1.3e-78 argR K Regulates arginine biosynthesis genes
APPPNAGC_03687 3.2e-147 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
APPPNAGC_03688 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APPPNAGC_03689 7.2e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
APPPNAGC_03690 9.7e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APPPNAGC_03691 8.7e-206 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APPPNAGC_03692 3.3e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APPPNAGC_03693 6.9e-66 yqhY S protein conserved in bacteria
APPPNAGC_03694 7.7e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
APPPNAGC_03695 5.1e-68 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APPPNAGC_03696 1.1e-56
APPPNAGC_03697 1.7e-88 spoIIIAH S SpoIIIAH-like protein
APPPNAGC_03698 7.6e-99 spoIIIAG S stage III sporulation protein AG
APPPNAGC_03699 1.7e-89 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
APPPNAGC_03700 2.5e-201 spoIIIAE S stage III sporulation protein AE
APPPNAGC_03701 1.6e-40 spoIIIAD S Stage III sporulation protein AD
APPPNAGC_03702 4.4e-29 spoIIIAC S stage III sporulation protein AC
APPPNAGC_03703 1.1e-81 spoIIIAB S Stage III sporulation protein
APPPNAGC_03704 9.2e-167 spoIIIAA S stage III sporulation protein AA
APPPNAGC_03705 1.7e-35 yqhV S Protein of unknown function (DUF2619)
APPPNAGC_03706 2.4e-47 S YfzA-like protein
APPPNAGC_03707 8e-94 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
APPPNAGC_03708 3.2e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APPPNAGC_03709 9.5e-192 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
APPPNAGC_03710 5.9e-88 yqhR S Conserved membrane protein YqhR
APPPNAGC_03711 1.5e-54
APPPNAGC_03712 5.4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
APPPNAGC_03713 6.5e-75 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
APPPNAGC_03714 2.5e-197 splB 4.1.99.14 L Spore photoproduct lyase
APPPNAGC_03715 4.6e-157 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
APPPNAGC_03716 0.0 helD 3.6.4.12 L DNA helicase
APPPNAGC_03717 1.8e-153 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
APPPNAGC_03718 1.9e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
APPPNAGC_03719 1.5e-283 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APPPNAGC_03720 2.8e-249 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APPPNAGC_03721 1.6e-202 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
APPPNAGC_03722 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
APPPNAGC_03723 1.9e-152 yqhG S Bacterial protein YqhG of unknown function
APPPNAGC_03724 6.6e-08 S Protein of unknown function (DUF2759)
APPPNAGC_03725 7.5e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
APPPNAGC_03726 2e-36 yqgY S Protein of unknown function (DUF2626)
APPPNAGC_03729 5e-78
APPPNAGC_03730 2e-10
APPPNAGC_03731 4.2e-69 mshD NU general secretion pathway protein
APPPNAGC_03732 1.4e-47 comGC U Required for transformation and DNA binding
APPPNAGC_03733 1.2e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
APPPNAGC_03741 5.1e-182 comGB NU COG1459 Type II secretory pathway, component PulF
APPPNAGC_03742 5.4e-176 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APPPNAGC_03743 0.0 yjcD 3.6.4.12 L DNA helicase
APPPNAGC_03744 2.1e-52
APPPNAGC_03745 3.5e-60 cotX S Spore Coat Protein X and V domain
APPPNAGC_03748 1.1e-135
APPPNAGC_03749 5.4e-119
APPPNAGC_03750 1.6e-137 Q ubiE/COQ5 methyltransferase family
APPPNAGC_03751 2.5e-56 yngL S Protein of unknown function (DUF1360)
APPPNAGC_03752 8.3e-137 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
APPPNAGC_03753 6.6e-162 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
APPPNAGC_03754 8.8e-150 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APPPNAGC_03755 2e-109 yjbM 2.7.6.5 S GTP pyrophosphokinase
APPPNAGC_03756 2.7e-61 yjbL S Belongs to the UPF0738 family
APPPNAGC_03757 4.4e-95 yjbK S protein conserved in bacteria
APPPNAGC_03758 4e-95 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
APPPNAGC_03759 5.6e-73 yjbI S COG2346 Truncated hemoglobins
APPPNAGC_03760 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
APPPNAGC_03761 5.5e-204 yjbF S Competence protein
APPPNAGC_03762 6.1e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
APPPNAGC_03763 1.3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APPPNAGC_03765 7.7e-97 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APPPNAGC_03766 4.4e-225 S Putative glycosyl hydrolase domain
APPPNAGC_03767 2e-09 yoeD G Helix-turn-helix domain
APPPNAGC_03768 6.5e-111 yplQ S protein, Hemolysin III
APPPNAGC_03769 1.6e-94 yueE S phosphohydrolase
APPPNAGC_03770 1.5e-98 stoA CO Redoxin
APPPNAGC_03772 2.4e-181 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
APPPNAGC_03773 1.5e-72 ctsR K Belongs to the CtsR family
APPPNAGC_03774 1.3e-93 mcsA 2.7.14.1 S protein with conserved CXXC pairs
APPPNAGC_03775 2.4e-195 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
APPPNAGC_03776 0.0 clpC O Belongs to the ClpA ClpB family
APPPNAGC_03777 1.5e-250 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APPPNAGC_03778 2.7e-194 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
APPPNAGC_03779 2e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
APPPNAGC_03780 7.6e-118 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
APPPNAGC_03781 1.6e-82 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
APPPNAGC_03782 1.5e-277 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APPPNAGC_03783 3.5e-120 cysE 2.3.1.30 E Serine acetyltransferase
APPPNAGC_03784 9e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
APPPNAGC_03785 5.7e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APPPNAGC_03786 1.2e-143 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APPPNAGC_03787 4.9e-85 yacP S RNA-binding protein containing a PIN domain
APPPNAGC_03788 3.6e-117 sigH K Belongs to the sigma-70 factor family
APPPNAGC_03789 6.1e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APPPNAGC_03790 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
APPPNAGC_03791 6.3e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APPPNAGC_03792 9.4e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APPPNAGC_03793 3.5e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APPPNAGC_03794 3.2e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APPPNAGC_03795 8.1e-117 rsmC 2.1.1.172 J Methyltransferase
APPPNAGC_03796 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APPPNAGC_03797 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APPPNAGC_03798 1.3e-35 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
APPPNAGC_03799 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APPPNAGC_03800 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APPPNAGC_03801 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APPPNAGC_03802 6.6e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APPPNAGC_03803 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
APPPNAGC_03804 1.5e-109 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APPPNAGC_03805 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
APPPNAGC_03806 2.3e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APPPNAGC_03807 2.2e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APPPNAGC_03808 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APPPNAGC_03809 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APPPNAGC_03810 8.7e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APPPNAGC_03811 4.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APPPNAGC_03812 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
APPPNAGC_03813 4.6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APPPNAGC_03814 5.1e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APPPNAGC_03815 6.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APPPNAGC_03816 2.3e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APPPNAGC_03817 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APPPNAGC_03818 4.9e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APPPNAGC_03819 1.3e-60 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APPPNAGC_03820 4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APPPNAGC_03821 2.7e-25 rpmD J Ribosomal protein L30
APPPNAGC_03822 3.3e-74 rplO J binds to the 23S rRNA
APPPNAGC_03823 1.8e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APPPNAGC_03824 2.9e-119 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APPPNAGC_03825 1.1e-141 map 3.4.11.18 E Methionine aminopeptidase
APPPNAGC_03826 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APPPNAGC_03827 1.4e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
APPPNAGC_03828 1.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APPPNAGC_03829 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APPPNAGC_03830 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APPPNAGC_03831 9.4e-59 rplQ J Ribosomal protein L17
APPPNAGC_03832 2.1e-157 ecfA P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APPPNAGC_03833 3.8e-143 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APPPNAGC_03834 2.6e-133 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APPPNAGC_03835 1.4e-144 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APPPNAGC_03836 2.9e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APPPNAGC_03837 1.7e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
APPPNAGC_03838 8.9e-82 S Protein of unknown function (DUF2975)
APPPNAGC_03839 1.6e-29 yozG K Transcriptional regulator
APPPNAGC_03841 3.4e-70 guaA J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APPPNAGC_03842 1.1e-16 rpsI J Belongs to the universal ribosomal protein uS9 family
APPPNAGC_03845 8.9e-80 ybaK S Protein of unknown function (DUF2521)
APPPNAGC_03846 4.4e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APPPNAGC_03847 1.1e-150 glcT K antiterminator
APPPNAGC_03848 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APPPNAGC_03849 1.6e-191 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
APPPNAGC_03850 3.9e-21 2.7.1.196, 2.7.1.205 G phosphotransferase system
APPPNAGC_03851 4.5e-75 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
APPPNAGC_03852 2.1e-30 licB 2.7.1.196, 2.7.1.205 G PFAM Phosphotransferase system, lactose cellobiose-specific IIB subunit
APPPNAGC_03853 6e-172 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APPPNAGC_03854 8.6e-73 ywpJ_2 S Sucrose-6F-phosphate phosphohydrolase
APPPNAGC_03855 9.2e-172 M1-530 S Protein of unknown function (DUF4127)
APPPNAGC_03856 1.5e-93 rpiR K transcriptional regulator, RpiR family
APPPNAGC_03857 1.5e-58 gerD S Spore gernimation protein
APPPNAGC_03858 2.2e-100 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
APPPNAGC_03859 3.4e-143 pdaB 3.5.1.104 G Polysaccharide deacetylase
APPPNAGC_03860 1.3e-33
APPPNAGC_03863 9.6e-22 S outer membrane
APPPNAGC_03866 1.8e-19 xhlA S Haemolysin XhlA
APPPNAGC_03867 3.6e-23 S Bacteriophage A118-like holin, Hol118
APPPNAGC_03868 1.9e-56 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APPPNAGC_03869 2.2e-23 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
APPPNAGC_03871 5.3e-105 S response regulator aspartate phosphatase
APPPNAGC_03872 2.3e-17
APPPNAGC_03873 2.6e-36
APPPNAGC_03874 2.3e-52
APPPNAGC_03875 3.2e-148 UW nuclease activity
APPPNAGC_03877 5.3e-99 2.1.1.72 V Restriction endonuclease
APPPNAGC_03878 2.4e-20
APPPNAGC_03880 1e-26
APPPNAGC_03881 2.9e-295 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
APPPNAGC_03882 2.1e-33
APPPNAGC_03883 1e-88 S DinB superfamily
APPPNAGC_03884 4.9e-56
APPPNAGC_03885 6.9e-133 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
APPPNAGC_03886 3.6e-285 malX 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
APPPNAGC_03887 1.8e-251 4.3.2.2, 5.5.1.2 F Adenylosuccinate lyase C-terminus
APPPNAGC_03888 1.2e-113 glvR K Helix-turn-helix domain, rpiR family
APPPNAGC_03889 1.2e-75
APPPNAGC_03894 5.9e-16
APPPNAGC_03896 7.4e-253 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
APPPNAGC_03897 1e-136 celG 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
APPPNAGC_03898 2.7e-244 pagL 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APPPNAGC_03899 9.6e-124 mngR K UTRA
APPPNAGC_03900 1.5e-104 S CAAX protease self-immunity
APPPNAGC_03901 7.7e-176 3.5.1.28 M COG3103 SH3 domain protein
APPPNAGC_03902 1.1e-163 ydhU P Catalase
APPPNAGC_03904 6.5e-145 S Nucleotidyltransferase domain
APPPNAGC_03905 1.1e-17
APPPNAGC_03906 1.1e-124 bshB1 S proteins, LmbE homologs
APPPNAGC_03907 2.1e-205 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
APPPNAGC_03908 3.9e-188 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APPPNAGC_03909 1.3e-176 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APPPNAGC_03910 1.3e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
APPPNAGC_03911 3.2e-164 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
APPPNAGC_03912 2.7e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
APPPNAGC_03913 2.7e-174 S Tetratricopeptide repeat
APPPNAGC_03914 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
APPPNAGC_03915 2.2e-243 mtaD 3.5.4.28, 3.5.4.31 F Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
APPPNAGC_03916 1.6e-14
APPPNAGC_03917 4.2e-22 ypmA S Protein of unknown function (DUF4264)
APPPNAGC_03918 5.3e-81 ypmB S protein conserved in bacteria
APPPNAGC_03919 1.2e-252 asnS 6.1.1.22 J asparaginyl-tRNA
APPPNAGC_03920 2.9e-125 dnaD L DNA replication protein DnaD
APPPNAGC_03921 1.2e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APPPNAGC_03922 0.0 ypbR S Dynamin family
APPPNAGC_03923 1.2e-21 S YpzG-like protein
APPPNAGC_03924 4.2e-186 yfhP S membrane-bound metal-dependent
APPPNAGC_03925 1.3e-201 mutY L A G-specific
APPPNAGC_03926 1.7e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_03927 9.1e-59
APPPNAGC_03928 4e-19 yfhS
APPPNAGC_03929 1.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APPPNAGC_03930 6e-15 S Small, acid-soluble spore protein, gamma-type
APPPNAGC_03931 1.5e-102 ygaC J Belongs to the UPF0374 family
APPPNAGC_03932 0.0 ygaD V ABC transporter
APPPNAGC_03933 5.1e-190 pslL G Acyltransferase family
APPPNAGC_03934 4.8e-160 3.13.1.3 P YhfZ C-terminal domain
APPPNAGC_03935 3.6e-55 S PRD domain
APPPNAGC_03936 2.7e-58 yhfU S Protein of unknown function DUF2620
APPPNAGC_03937 3.7e-222 yhfT S Protein of unknown function
APPPNAGC_03938 1.4e-172 php S Phosphotriesterase family
APPPNAGC_03939 8.6e-204 2.9.1.1 E Cys/Met metabolism PLP-dependent enzyme
APPPNAGC_03940 1.6e-216 yhfX E Alanine racemase, N-terminal domain
APPPNAGC_03941 7e-228 yhfW G Metalloenzyme superfamily
APPPNAGC_03942 0.0 O DnaJ molecular chaperone homology domain
APPPNAGC_03943 0.0 hscC O Hsp70 protein
APPPNAGC_03944 4.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
APPPNAGC_03945 7.8e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
APPPNAGC_03946 2.7e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
APPPNAGC_03947 9.7e-174 agpT K AraC-like ligand binding domain
APPPNAGC_03948 1.4e-245 ugpB1 G Bacterial extracellular solute-binding protein
APPPNAGC_03949 1.7e-146 M1-465 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_03950 3.3e-158 P Binding-protein-dependent transport system inner membrane component
APPPNAGC_03951 3.6e-48 esxA S Belongs to the WXG100 family
APPPNAGC_03952 7.2e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
APPPNAGC_03953 1.8e-208 essB S WXG100 protein secretion system (Wss), protein YukC
APPPNAGC_03954 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
APPPNAGC_03955 0.0 esaA S domain protein
APPPNAGC_03956 7.9e-71 S Family of unknown function (DUF5383)
APPPNAGC_03957 2.4e-44
APPPNAGC_03958 1.2e-46
APPPNAGC_03959 1e-42
APPPNAGC_03960 1.4e-244 S nuclease activity
APPPNAGC_03962 3.5e-49
APPPNAGC_03963 3.4e-09
APPPNAGC_03964 1.2e-08 S nuclease activity
APPPNAGC_03966 3.9e-21 pepF E oligoendopeptidase F
APPPNAGC_03967 6.5e-307 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
APPPNAGC_03968 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
APPPNAGC_03969 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
APPPNAGC_03970 3.2e-284 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
APPPNAGC_03971 6.7e-111 citT T response regulator
APPPNAGC_03973 1.9e-186 S Tripartite tricarboxylate transporter family receptor
APPPNAGC_03974 1.7e-68 S Tripartite tricarboxylate transporter TctB family
APPPNAGC_03975 1.4e-257 tctA S Tripartite tricarboxylate transporter TctA family
APPPNAGC_03977 1.5e-68 doc S Fic/DOC family
APPPNAGC_03978 2.8e-08
APPPNAGC_03979 2.6e-29 yebG S NETI protein
APPPNAGC_03980 2.1e-66 S Calcium/calmodulin dependent protein kinase II association domain
APPPNAGC_03981 1.6e-94
APPPNAGC_03982 3.4e-120 S PFAM AIG2 family protein
APPPNAGC_03983 1.5e-95 rimL 1.1.1.25 J Acetyltransferase (GNAT) domain
APPPNAGC_03984 4.3e-127 S CAAX protease self-immunity
APPPNAGC_03985 4.5e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APPPNAGC_03986 1.1e-206 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APPPNAGC_03987 6e-249 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APPPNAGC_03988 1.5e-127 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
APPPNAGC_03989 1.4e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APPPNAGC_03990 2.4e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APPPNAGC_03991 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APPPNAGC_03992 1e-270 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APPPNAGC_03993 6.6e-190 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
APPPNAGC_03994 6.7e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APPPNAGC_03995 2.2e-282 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
APPPNAGC_03996 5.7e-228 purD 6.3.4.13 F Belongs to the GARS family
APPPNAGC_03997 1e-199 cpg2 3.4.17.11 E Peptidase dimerisation domain
APPPNAGC_03998 2.4e-146 fhuD P Periplasmic binding protein
APPPNAGC_03999 3e-82 ttr K GCN5 family acetyltransferase
APPPNAGC_04000 1.8e-193 yxjM T Signal transduction histidine kinase
APPPNAGC_04001 1.1e-107 KT LuxR family transcriptional regulator
APPPNAGC_04002 4e-170 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
APPPNAGC_04003 3e-218 V COG0842 ABC-type multidrug transport system, permease component
APPPNAGC_04004 3.7e-188 V COG0842 ABC-type multidrug transport system, permease component
APPPNAGC_04006 4.9e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
APPPNAGC_04007 1.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APPPNAGC_04008 1.2e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APPPNAGC_04009 1.3e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APPPNAGC_04010 7.2e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
APPPNAGC_04011 3.6e-146 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
APPPNAGC_04012 5.2e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
APPPNAGC_04013 4e-262 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APPPNAGC_04014 1.3e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
APPPNAGC_04015 1.3e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APPPNAGC_04016 6.5e-142 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
APPPNAGC_04017 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APPPNAGC_04018 3.9e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
APPPNAGC_04019 8.8e-262 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APPPNAGC_04020 9.3e-175 KLT serine threonine protein kinase
APPPNAGC_04021 4.6e-129 yabS S protein containing a von Willebrand factor type A (vWA) domain
APPPNAGC_04022 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
APPPNAGC_04023 1.3e-222 citM C Citrate transporter
APPPNAGC_04025 2.2e-70 yabR J RNA binding protein (contains ribosomal protein S1 domain)
APPPNAGC_04026 8.2e-61 divIC D Septum formation initiator
APPPNAGC_04027 1e-64 yabQ S spore cortex biosynthesis protein
APPPNAGC_04028 1.3e-51 yabP S Sporulation protein YabP
APPPNAGC_04029 1.9e-101 MA20_20865 3.6.1.27 S SNARE associated Golgi protein
APPPNAGC_04030 6.2e-196 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
APPPNAGC_04031 6.8e-84 2.3.1.128 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APPPNAGC_04032 2.1e-174 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APPPNAGC_04033 1.3e-114 S hydrolase
APPPNAGC_04034 9e-24 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
APPPNAGC_04035 6.1e-266 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
APPPNAGC_04036 9.4e-265 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APPPNAGC_04037 4.4e-88 S Yip1 domain
APPPNAGC_04038 2.3e-198 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APPPNAGC_04039 2.4e-97 S Yip1 domain
APPPNAGC_04040 2.7e-94 spoVT K stage V sporulation protein
APPPNAGC_04041 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APPPNAGC_04042 1.2e-38 yabK S Peptide ABC transporter permease
APPPNAGC_04043 1.4e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APPPNAGC_04044 2.2e-90 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
APPPNAGC_04045 4.5e-169 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APPPNAGC_04046 2.6e-250 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APPPNAGC_04048 1.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
APPPNAGC_04049 1.4e-97 licR 2.7.1.197 GKT Mga helix-turn-helix domain
APPPNAGC_04050 1e-133 K Helix-turn-helix XRE-family like proteins
APPPNAGC_04051 8.4e-89 IV02_12955 U MarC family integral membrane protein
APPPNAGC_04052 1.3e-287 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
APPPNAGC_04053 3.3e-52 S Belongs to the HesB IscA family
APPPNAGC_04054 5.9e-84 Q ubiE/COQ5 methyltransferase family
APPPNAGC_04055 9.6e-187 G Transmembrane secretion effector
APPPNAGC_04056 1.6e-10 G Transmembrane secretion effector
APPPNAGC_04057 3.9e-20 S Protein of unknown function (DUF2564)
APPPNAGC_04058 1.7e-287 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Belongs to the FGGY kinase family
APPPNAGC_04059 2.2e-50
APPPNAGC_04060 4e-68 S Src homology 3 domains
APPPNAGC_04061 5.7e-267 P Spore gernimation protein GerA
APPPNAGC_04062 2.1e-197 E Spore germination protein
APPPNAGC_04063 4.4e-197 S Spore germination B3/ GerAC like, C-terminal
APPPNAGC_04065 2.4e-154 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
APPPNAGC_04066 5.6e-62
APPPNAGC_04067 2.7e-61 pcaC 3.1.1.24, 4.1.1.44 S Carboxymuconolactone decarboxylase family
APPPNAGC_04068 8.2e-304 2.2.1.6 EH Thiamine pyrophosphate enzyme, central domain
APPPNAGC_04069 7.4e-175 S Oxidoreductase
APPPNAGC_04070 2.3e-220 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
APPPNAGC_04071 3e-38
APPPNAGC_04072 5.5e-68 rnhA 3.1.26.4 L An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
APPPNAGC_04073 2.3e-48 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APPPNAGC_04074 1.3e-94 ypsA S Belongs to the UPF0398 family
APPPNAGC_04076 3.3e-217 yprB L RNase_H superfamily
APPPNAGC_04077 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
APPPNAGC_04078 0.0 pepF E oligoendopeptidase F
APPPNAGC_04079 1.2e-258 gerAA EG Spore germination protein
APPPNAGC_04080 3.2e-187 gerAB E Spore germination protein
APPPNAGC_04081 4.7e-197 gerAC S Spore germination B3/ GerAC like, C-terminal
APPPNAGC_04082 6.6e-80
APPPNAGC_04083 2.7e-106 mhqD S Carboxylesterase
APPPNAGC_04084 1.8e-178 mhqA E COG0346 Lactoylglutathione lyase and related lyases
APPPNAGC_04085 3.1e-17
APPPNAGC_04086 8.4e-146 ycsE S hydrolases of the HAD superfamily
APPPNAGC_04087 1.1e-81
APPPNAGC_04089 1.9e-153 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APPPNAGC_04090 5.3e-35 S Family of unknown function (DUF5344)
APPPNAGC_04091 1e-146 yjqC P Catalase
APPPNAGC_04092 9.5e-107 E Lysine exporter protein LysE YggA
APPPNAGC_04093 3.2e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
APPPNAGC_04094 4.6e-117 yhcQ M Spore coat protein
APPPNAGC_04096 7.4e-172 eutC 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
APPPNAGC_04097 1.3e-168 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
APPPNAGC_04098 1.5e-204 mntH P H( )-stimulated, divalent metal cation uptake system
APPPNAGC_04099 2.3e-116 S HTH domain
APPPNAGC_04100 3.9e-189 speB 3.5.3.11 E Arginase family
APPPNAGC_04101 4.1e-127 T Transcriptional regulator
APPPNAGC_04102 2.4e-182 T PhoQ Sensor
APPPNAGC_04103 4.6e-155 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
APPPNAGC_04104 7.4e-121 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
APPPNAGC_04105 1.3e-113 ydfE S Flavin reductase like domain
APPPNAGC_04106 9.5e-42 K Bacterial regulatory proteins, tetR family
APPPNAGC_04107 3.9e-149 EGP Major facilitator Superfamily
APPPNAGC_04108 1.4e-111 S ABC-2 family transporter protein
APPPNAGC_04109 5.5e-164 ycbN V ABC transporter, ATP-binding protein
APPPNAGC_04110 2.9e-168 T PhoQ Sensor
APPPNAGC_04111 1.1e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_04112 3e-237 hisD2 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APPPNAGC_04113 1.3e-171 K helix_turn _helix lactose operon repressor
APPPNAGC_04114 2.8e-230 EG COG2610 H gluconate symporter and related permeases
APPPNAGC_04115 5.2e-195 M Domain of unknown function DUF11
APPPNAGC_04116 1.5e-100 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
APPPNAGC_04117 4.7e-31 S Sporulation inhibitor A
APPPNAGC_04118 1.5e-157 chiA 3.2.1.14, 3.2.1.17 AA10,CBM15,CBM73,GH18 D Lytic polysaccharide mono-oxygenase, cellulose-degrading
APPPNAGC_04119 1.7e-142 C KR domain
APPPNAGC_04120 1.5e-56 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
APPPNAGC_04121 1.1e-178 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
APPPNAGC_04122 1e-99 srlA G PTS system enzyme II sorbitol-specific factor
APPPNAGC_04123 1.5e-74 gutM K Glucitol operon activator
APPPNAGC_04124 2.4e-173 sorC K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
APPPNAGC_04126 1.3e-72 S SnoaL-like polyketide cyclase
APPPNAGC_04127 2.1e-89 yokH G SMI1 / KNR4 family
APPPNAGC_04128 1.2e-61 Q ubiE/COQ5 methyltransferase family
APPPNAGC_04129 5.5e-97 yrkC G Cupin domain
APPPNAGC_04130 1.5e-138 S TraX protein
APPPNAGC_04131 8.6e-165 mviM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
APPPNAGC_04132 1.3e-28 cspL K 'Cold-shock' DNA-binding domain
APPPNAGC_04133 8.3e-76 carD K Transcription factor
APPPNAGC_04134 5.9e-49 arsR K ArsR family transcriptional regulator
APPPNAGC_04135 4e-65 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APPPNAGC_04136 3.3e-53 arsR K transcriptional
APPPNAGC_04137 2.5e-218 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
APPPNAGC_04138 3.2e-74 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
APPPNAGC_04140 2.2e-209 oxdD 4.1.1.2 G Oxalate decarboxylase
APPPNAGC_04141 8.9e-159 catE 1.13.11.2 S glyoxalase
APPPNAGC_04143 2.2e-109 ydhC K FCD
APPPNAGC_04144 2.7e-199 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
APPPNAGC_04145 1.2e-63 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APPPNAGC_04146 6.6e-117 1.14.12.17 C Oxidoreductase NAD-binding domain
APPPNAGC_04147 0.0 L ABC transporter
APPPNAGC_04148 4.3e-73 yndB K Activator of Hsp90 ATPase homolog 1-like protein
APPPNAGC_04149 3.4e-55 smtB K helix_turn_helix, Arsenical Resistance Operon Repressor
APPPNAGC_04150 1.7e-63 frataxin S Domain of unknown function (DU1801)
APPPNAGC_04151 4.7e-49 azlD E Branched-chain amino acid transport protein (AzlD)
APPPNAGC_04152 7.9e-126 azlC E AzlC protein
APPPNAGC_04153 6.2e-73 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APPPNAGC_04154 4e-71 phnB5 S 3-demethylubiquinone-9 3-methyltransferase
APPPNAGC_04155 1.4e-46 GM NmrA-like family
APPPNAGC_04156 7.7e-183 3.1.3.41, 3.6.1.55 F Belongs to the Nudix hydrolase family
APPPNAGC_04157 3.3e-65 2.3.1.128 J L-PSP family endoribonuclease
APPPNAGC_04158 1.4e-153 phzF 5.3.3.17 S Phenazine biosynthesis-like protein
APPPNAGC_04159 0.0 K transcriptional regulator, MtlR
APPPNAGC_04160 6.2e-157 4.1.2.13 G Fructose-bisphosphate aldolase class-II
APPPNAGC_04161 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
APPPNAGC_04162 7e-161 aadK G Streptomycin adenylyltransferase
APPPNAGC_04163 5.5e-95
APPPNAGC_04165 1.2e-26
APPPNAGC_04166 1.2e-203 dhaT 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
APPPNAGC_04167 2.4e-11
APPPNAGC_04168 9.6e-267 cckA 2.7.13.3 T GAF domain
APPPNAGC_04169 2.1e-255 T Sigma-54 interaction domain
APPPNAGC_04170 7.4e-197 adhA 1.1.1.1 C alcohol dehydrogenase
APPPNAGC_04171 5.3e-273 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
APPPNAGC_04172 4.6e-177 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
APPPNAGC_04174 1.9e-264 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
APPPNAGC_04175 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APPPNAGC_04176 4.1e-53 yaaQ S protein conserved in bacteria
APPPNAGC_04177 4.8e-182 holB 2.7.7.7 L DNA polymerase III
APPPNAGC_04178 2.2e-143 yaaT S stage 0 sporulation protein
APPPNAGC_04179 3e-38 yabA L Involved in initiation control of chromosome replication
APPPNAGC_04180 1.1e-133 yabB 2.1.1.223 S Conserved hypothetical protein 95
APPPNAGC_04181 4.2e-40 yazA L endonuclease containing a URI domain
APPPNAGC_04182 4.4e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APPPNAGC_04183 1.1e-43 abrB K COG2002 Regulators of stationary sporulation gene expression
APPPNAGC_04184 6.7e-173 S NurA
APPPNAGC_04185 0.0 S Domain of unknown function DUF87
APPPNAGC_04186 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APPPNAGC_04187 2.3e-81 K DNA-binding transcription factor activity
APPPNAGC_04188 4.4e-183 pelB 4.2.2.2 G Amb_all
APPPNAGC_04190 5e-277 S ABC transporter
APPPNAGC_04191 2.2e-114 T protein histidine kinase activity
APPPNAGC_04192 4.6e-241 S Protein of unknown function (DUF3298)
APPPNAGC_04193 1.4e-144 tatD L hydrolase, TatD
APPPNAGC_04194 3.5e-199 rpfB GH23 T protein conserved in bacteria
APPPNAGC_04195 9.7e-101 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APPPNAGC_04196 5.7e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APPPNAGC_04197 2.9e-162 yabG S peptidase
APPPNAGC_04198 1.2e-39 veg S protein conserved in bacteria
APPPNAGC_04199 3.3e-25 sspF S DNA topological change
APPPNAGC_04200 1.7e-162 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APPPNAGC_04201 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
APPPNAGC_04202 1.6e-61 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
APPPNAGC_04203 1.5e-18 bofA S Sigma-K factor-processing regulatory protein BofA
APPPNAGC_04204 3.4e-30 S Protein of unknown function (DUF2508)
APPPNAGC_04205 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APPPNAGC_04206 1.8e-34 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APPPNAGC_04207 5.3e-306 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APPPNAGC_04208 1.1e-110 K Sigma-70, region 4
APPPNAGC_04209 1.4e-101 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APPPNAGC_04210 4.3e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APPPNAGC_04211 3e-290 gsiB_4 E COG0747 ABC-type dipeptide transport system, periplasmic component
APPPNAGC_04212 3.4e-158 EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_04213 5.9e-169 EP COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_04214 2.4e-192 oppD P Belongs to the ABC transporter superfamily
APPPNAGC_04215 4.9e-190 E Belongs to the ABC transporter superfamily
APPPNAGC_04216 4.2e-127 glnQ2 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
APPPNAGC_04217 4.2e-110 glnP E Polar amino acid ABC transporter, inner membrane subunit
APPPNAGC_04218 4.7e-143 glnH ET Ligated ion channel L-glutamate- and glycine-binding site
APPPNAGC_04219 3.1e-262 gabD_2 1.2.1.9 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APPPNAGC_04220 1.9e-192 hom2 1.1.1.3 E Homoserine dehydrogenase
APPPNAGC_04221 1.8e-223 amaA 3.5.1.47 E Peptidase dimerisation domain
APPPNAGC_04222 6.6e-226 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E cystathionine
APPPNAGC_04223 1.5e-233 eutD 3.4.13.9, 3.5.4.44 E Creatinase/Prolidase N-terminal domain
APPPNAGC_04224 4.9e-236 nhaC C Na H antiporter
APPPNAGC_04225 1.5e-71 rocG 1.4.1.2, 1.4.1.3 E Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
APPPNAGC_04226 5.5e-73 gluD 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
APPPNAGC_04227 9.3e-228 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
APPPNAGC_04228 7.6e-250 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
APPPNAGC_04229 1.4e-309 QT COG2508 Regulator of polyketide synthase expression
APPPNAGC_04230 1.7e-145 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
APPPNAGC_04231 1.9e-215 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APPPNAGC_04232 8.3e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
APPPNAGC_04233 7.4e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
APPPNAGC_04234 1.9e-143 yaaC S YaaC-like Protein
APPPNAGC_04235 2.9e-168 K Putative sugar-binding domain
APPPNAGC_04236 2.9e-60 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
APPPNAGC_04237 1.4e-181 srlE 2.7.1.198 G PTS system glucitol sorbitol-specific transporter subunit IIB
APPPNAGC_04238 5.6e-89 srlA G PTS system enzyme II sorbitol-specific factor
APPPNAGC_04239 5.4e-66 K Glucitol operon activator protein (GutM)
APPPNAGC_04240 8.2e-235 thrA E SAF
APPPNAGC_04241 4.6e-36 ptsH G PTS HPr component phosphorylation site
APPPNAGC_04242 9.5e-116
APPPNAGC_04243 2.9e-91 S VanZ like family
APPPNAGC_04244 9.6e-77 yybA 2.3.1.57 K transcriptional
APPPNAGC_04245 3.9e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APPPNAGC_04246 2.2e-171 ssuA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
APPPNAGC_04247 5.6e-104 ssuC P Binding-protein-dependent transport system inner membrane component
APPPNAGC_04248 1.1e-155 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
APPPNAGC_04249 9.2e-253 glcF C Glycolate oxidase
APPPNAGC_04250 7.7e-258 glcD 1.1.3.15 C Glycolate oxidase subunit
APPPNAGC_04251 2.5e-203 ysfB KT regulator
APPPNAGC_04252 2e-233 yxiO S COG2270 Permeases of the major facilitator superfamily
APPPNAGC_04253 4.5e-141 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
APPPNAGC_04254 1.5e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
APPPNAGC_04256 4.6e-296 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
APPPNAGC_04257 1.7e-79
APPPNAGC_04258 6.3e-148
APPPNAGC_04259 8.8e-209 ysh1 J Metallo-beta-lactamase superfamily
APPPNAGC_04260 1.7e-288 ftpA P Binding-protein-dependent transport system inner membrane component
APPPNAGC_04261 6.1e-188 ftpB P Bacterial extracellular solute-binding protein
APPPNAGC_04262 5.6e-183 phnT 3.6.3.30 P ABC transporter
APPPNAGC_04263 3e-159 rbcR1 K Transcriptional regulator
APPPNAGC_04264 3.3e-121 S Haloacid dehalogenase-like hydrolase
APPPNAGC_04265 5.7e-54 S Family of unknown function (DUF5367)
APPPNAGC_04266 2.9e-102 K Bacterial regulatory proteins, tetR family
APPPNAGC_04268 1.8e-162 EG EamA-like transporter family
APPPNAGC_04269 4.6e-247 ywoF P Right handed beta helix region
APPPNAGC_04270 2.8e-88 mutT 3.6.1.13, 3.6.1.55 L nUDIX hydrolase
APPPNAGC_04271 3e-09
APPPNAGC_04272 1.2e-155 S CAAX amino terminal protease family protein
APPPNAGC_04273 0.0 copA 3.6.3.54 P P-type ATPase
APPPNAGC_04275 0.0 V ABC transporter (permease)
APPPNAGC_04276 9.5e-141 yvcR V ABC transporter, ATP-binding protein
APPPNAGC_04277 8.7e-190 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
APPPNAGC_04278 1.8e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APPPNAGC_04279 5e-38 3.1.3.48 GM protein tyrosine phosphatase activity
APPPNAGC_04280 3.3e-49
APPPNAGC_04281 1.4e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
APPPNAGC_04282 0.0 rocB E arginine degradation protein
APPPNAGC_04283 9.1e-273 mdr EGP Major facilitator Superfamily
APPPNAGC_04284 1.2e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
APPPNAGC_04285 2.7e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
APPPNAGC_04286 5.3e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APPPNAGC_04287 1.7e-126 lacR K DeoR C terminal sensor domain
APPPNAGC_04288 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
APPPNAGC_04289 3.9e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APPPNAGC_04290 7.9e-230 G ABC transporter substrate-binding protein
APPPNAGC_04291 4e-159 G Binding-protein-dependent transport system inner membrane component
APPPNAGC_04292 5.8e-155 P PFAM binding-protein-dependent transport systems inner membrane component
APPPNAGC_04293 1.8e-59 Z012_01525 FJ tRNA wobble adenosine to inosine editing
APPPNAGC_04294 2.7e-12 S Inner spore coat protein D
APPPNAGC_04295 1.2e-181 ywtF K Transcriptional regulator
APPPNAGC_04296 3.2e-80 asnC K helix_turn_helix ASNC type
APPPNAGC_04297 4.5e-191 oppD P Belongs to the ABC transporter superfamily
APPPNAGC_04298 1.8e-146 oppF P Belongs to the ABC transporter superfamily
APPPNAGC_04299 1.2e-172 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APPPNAGC_04300 4e-151 oppC EP binding-protein-dependent transport systems inner membrane component
APPPNAGC_04301 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
APPPNAGC_04302 1.3e-102 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
APPPNAGC_04303 1.1e-113 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
APPPNAGC_04304 2e-200 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
APPPNAGC_04305 2.1e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APPPNAGC_04306 1.1e-147 degV S protein conserved in bacteria
APPPNAGC_04307 1.6e-252 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
APPPNAGC_04308 4.3e-124 comFC S Phosphoribosyl transferase domain
APPPNAGC_04309 1.7e-75 yvyF S flagellar protein
APPPNAGC_04310 3.6e-39 N Anti-sigma-28 factor, FlgM
APPPNAGC_04312 2.1e-280 flgK N flagellar hook-associated protein
APPPNAGC_04313 2.7e-186 flgL N Belongs to the bacterial flagellin family
APPPNAGC_04314 8.2e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
APPPNAGC_04315 7.7e-33 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
APPPNAGC_04316 5.7e-47 flaG N flagellar protein FlaG
APPPNAGC_04317 1.6e-289 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
APPPNAGC_04318 6.7e-66 fliS N flagellar protein FliS
APPPNAGC_04320 6.3e-146
APPPNAGC_04321 3.8e-30 cspB K cold-shock protein
APPPNAGC_04322 1.2e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APPPNAGC_04323 2.7e-10
APPPNAGC_04324 2.9e-139 yjbA S Belongs to the UPF0736 family
APPPNAGC_04325 1.7e-153 yjaZ O Zn-dependent protease
APPPNAGC_04326 3.4e-135 ywaC 2.7.6.5 S protein conserved in bacteria
APPPNAGC_04327 8.2e-179 coaA 2.7.1.33 F Pantothenic acid kinase
APPPNAGC_04328 2e-98 J protein with SCP PR1 domains
APPPNAGC_04329 3.3e-101 3.5.1.28 M Cell Wall Hydrolase
APPPNAGC_04331 0.0 cca 2.7.7.19, 2.7.7.72, 3.1.13.3, 3.1.3.7 J Poly A polymerase head domain
APPPNAGC_04332 5.2e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APPPNAGC_04333 3.8e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APPPNAGC_04336 1.8e-13 comZ S ComZ
APPPNAGC_04337 8.1e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
APPPNAGC_04338 3.1e-137 5.1.3.2 GM RmlD substrate binding domain
APPPNAGC_04339 1.5e-118 yjaU I carboxylic ester hydrolase activity
APPPNAGC_04340 1.6e-166 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APPPNAGC_04341 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
APPPNAGC_04342 1.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
APPPNAGC_04343 4.3e-214 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
APPPNAGC_04344 3.1e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
APPPNAGC_04345 8.3e-224 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
APPPNAGC_04346 5.2e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
APPPNAGC_04348 5.7e-86 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
APPPNAGC_04349 1.6e-45 yppE S Bacterial domain of unknown function (DUF1798)
APPPNAGC_04350 6e-15
APPPNAGC_04351 2.6e-233 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
APPPNAGC_04352 2.4e-95 pfpI 3.5.1.124 S DJ-1/PfpI family
APPPNAGC_04353 3.8e-168 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APPPNAGC_04354 3.5e-52 yusE CO cell redox homeostasis
APPPNAGC_04355 1.6e-76 yphP S Belongs to the UPF0403 family
APPPNAGC_04356 1.5e-73 CO Thioredoxin-like
APPPNAGC_04357 7e-138 T Calcineurin-like phosphoesterase superfamily domain
APPPNAGC_04358 1.1e-142 ypgR C COG0694 Thioredoxin-like proteins and domains
APPPNAGC_04359 9.5e-30
APPPNAGC_04360 1.3e-84 ydbS S Bacterial PH domain
APPPNAGC_04361 1.4e-230 ydbT S Membrane
APPPNAGC_04362 4.4e-191 S Protein of unknown function (DUF2777)
APPPNAGC_04363 7e-167
APPPNAGC_04364 2e-127 telA P Belongs to the TelA family
APPPNAGC_04365 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
APPPNAGC_04366 5.2e-289 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
APPPNAGC_04367 1.1e-112 ypjP S YpjP-like protein
APPPNAGC_04368 4.2e-37
APPPNAGC_04370 4.6e-61 kapB G Kinase associated protein B
APPPNAGC_04371 6.2e-53 atl 3.2.1.96, 3.4.17.14, 3.5.1.28, 6.1.1.12 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APPPNAGC_04372 2.6e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
APPPNAGC_04373 9.6e-278 M Glycosyltransferase like family 2
APPPNAGC_04374 0.0 tagF 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
APPPNAGC_04375 9e-71 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
APPPNAGC_04376 4.9e-134 2.7.8.34 I CDP-alcohol phosphatidyltransferase
APPPNAGC_04377 6.8e-231 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APPPNAGC_04378 1.5e-250 wcaJ M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
APPPNAGC_04379 2e-194 exoA M Glycosyltransferase like family 2
APPPNAGC_04380 1.3e-129 E lipolytic protein G-D-S-L family
APPPNAGC_04381 3.9e-63 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
APPPNAGC_04382 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APPPNAGC_04383 9.9e-191 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APPPNAGC_04384 1.5e-112 ymaB S MutT family
APPPNAGC_04385 1e-96 pncA Q COG1335 Amidases related to nicotinamidase
APPPNAGC_04386 1.2e-26
APPPNAGC_04387 7.7e-76 S LXG domain of WXG superfamily
APPPNAGC_04388 5.4e-83
APPPNAGC_04389 2.8e-61 U LXG domain of WXG superfamily
APPPNAGC_04390 1.9e-81 yokJ S SMI1 / KNR4 family (SUKH-1)
APPPNAGC_04391 5.6e-34 T Protein conserved in bacteria
APPPNAGC_04392 2.1e-22
APPPNAGC_04393 3.4e-79
APPPNAGC_04395 4.3e-14
APPPNAGC_04396 7.3e-23
APPPNAGC_04397 1.4e-54 M self proteolysis
APPPNAGC_04398 8.8e-59
APPPNAGC_04399 5.5e-44 yokK S SMI1-KNR4 cell-wall
APPPNAGC_04400 6.2e-21
APPPNAGC_04401 1.9e-22
APPPNAGC_04403 2.5e-95 K Belongs to the GbsR family
APPPNAGC_04404 4.7e-219 gbuA 3.6.3.32 E glycine betaine
APPPNAGC_04405 5.6e-147 proW P glycine betaine
APPPNAGC_04406 1.2e-155 opuAC E glycine betaine
APPPNAGC_04407 4.5e-194 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
APPPNAGC_04408 0.0 3.5.4.2 F adenine deaminase
APPPNAGC_04409 1.2e-49 yerC S protein conserved in bacteria
APPPNAGC_04410 8.2e-145 ykrA S hydrolases of the HAD superfamily
APPPNAGC_04411 1.9e-29
APPPNAGC_04412 9.9e-46 csoR S transcriptional
APPPNAGC_04413 1.1e-27 copP P Heavy-metal-associated domain
APPPNAGC_04414 1.4e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
APPPNAGC_04416 5e-190 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
APPPNAGC_04417 6.9e-215 E Peptidase family M28
APPPNAGC_04418 1.5e-104 GM NmrA-like family
APPPNAGC_04419 8.7e-177 ytvI S AI-2E family transporter
APPPNAGC_04420 2.4e-80 copC S CopC domain
APPPNAGC_04422 2.1e-194 yhdY M Mechanosensitive ion channel
APPPNAGC_04423 4.8e-185 T Metal dependent phosphohydrolases with conserved 'HD' motif.
APPPNAGC_04424 1.5e-145 S Membrane transport protein
APPPNAGC_04425 1.3e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APPPNAGC_04426 1.8e-223 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
APPPNAGC_04427 4.3e-211 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APPPNAGC_04428 3.1e-37 ykuS S Belongs to the UPF0180 family
APPPNAGC_04430 1.4e-169 glcA G Glycoside hydrolase family 16
APPPNAGC_04433 8.3e-53
APPPNAGC_04435 4.9e-08
APPPNAGC_04436 4.6e-88
APPPNAGC_04437 3.6e-58 ygzB S UPF0295 protein
APPPNAGC_04438 1.5e-79 perR P Belongs to the Fur family
APPPNAGC_04439 2.7e-48 S Cyclic-di-AMP receptor
APPPNAGC_04440 1.7e-171 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APPPNAGC_04441 8.1e-87 bcp 1.11.1.15 O Peroxiredoxin
APPPNAGC_04442 3.1e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
APPPNAGC_04443 1.2e-183 ygaE S Membrane
APPPNAGC_04444 4e-159 yppC S Protein of unknown function (DUF2515)
APPPNAGC_04445 8.5e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APPPNAGC_04446 0.0 pbp1A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
APPPNAGC_04447 1.3e-93 S nuclease activity
APPPNAGC_04448 2.9e-84 S SMI1-KNR4 cell-wall
APPPNAGC_04449 8.2e-66
APPPNAGC_04450 1.8e-80 S SMI1-KNR4 cell-wall
APPPNAGC_04451 2.4e-36 L Transposase
APPPNAGC_04452 1.7e-100 L HTH-like domain
APPPNAGC_04453 2.9e-81 L Transposase IS200 like
APPPNAGC_04454 4.8e-22 S membrane
APPPNAGC_04457 1.7e-07
APPPNAGC_04459 1.7e-07

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)