ORF_ID e_value Gene_name EC_number CAZy COGs Description
HLNCHOAK_00001 1.4e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HLNCHOAK_00002 3.2e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
HLNCHOAK_00003 2.3e-246 yoeA V MATE efflux family protein
HLNCHOAK_00004 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HLNCHOAK_00006 2.2e-96 L Integrase
HLNCHOAK_00007 3e-34 yoeD G Helix-turn-helix domain
HLNCHOAK_00008 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HLNCHOAK_00009 4.4e-155 gltR1 K Transcriptional regulator
HLNCHOAK_00010 1.2e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HLNCHOAK_00011 4.2e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HLNCHOAK_00012 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HLNCHOAK_00013 7.8e-155 gltC K Transcriptional regulator
HLNCHOAK_00014 2.7e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLNCHOAK_00015 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLNCHOAK_00016 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HLNCHOAK_00017 1.8e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_00018 3.5e-38 yoxC S Bacterial protein of unknown function (DUF948)
HLNCHOAK_00019 1.7e-134 yoxB
HLNCHOAK_00020 4.8e-48 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLNCHOAK_00021 2.6e-233 yoaB EGP Major facilitator Superfamily
HLNCHOAK_00022 9.7e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HLNCHOAK_00023 9.9e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLNCHOAK_00024 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLNCHOAK_00025 8.7e-32 yoaF
HLNCHOAK_00026 1.9e-171 iolT EGP Major facilitator Superfamily
HLNCHOAK_00027 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
HLNCHOAK_00028 3.5e-150 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
HLNCHOAK_00029 4.4e-90 purR K Transcriptional regulator
HLNCHOAK_00030 2.2e-07
HLNCHOAK_00031 7e-14
HLNCHOAK_00032 8.2e-37 S Protein of unknown function (DUF4025)
HLNCHOAK_00033 1.2e-180 mcpU NT methyl-accepting chemotaxis protein
HLNCHOAK_00034 3.7e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HLNCHOAK_00035 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HLNCHOAK_00036 2.3e-111 yoaK S Membrane
HLNCHOAK_00037 1.4e-195 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HLNCHOAK_00038 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
HLNCHOAK_00041 1.8e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
HLNCHOAK_00043 2.1e-19 yoaP 3.1.3.18 K YoaP-like
HLNCHOAK_00044 1.2e-83
HLNCHOAK_00045 1.3e-170 yoaR V vancomycin resistance protein
HLNCHOAK_00046 3.6e-74 yoaS S Protein of unknown function (DUF2975)
HLNCHOAK_00047 2.2e-29 yozG K Transcriptional regulator
HLNCHOAK_00048 1.5e-149 yoaT S Protein of unknown function (DUF817)
HLNCHOAK_00049 3.3e-158 yoaU K LysR substrate binding domain
HLNCHOAK_00050 1e-154 yijE EG EamA-like transporter family
HLNCHOAK_00051 2.7e-76 yoaW
HLNCHOAK_00052 1.4e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HLNCHOAK_00053 2.2e-165 bla 3.5.2.6 V beta-lactamase
HLNCHOAK_00056 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HLNCHOAK_00057 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HLNCHOAK_00058 8.8e-37 S TM2 domain
HLNCHOAK_00059 2.4e-56 K Helix-turn-helix
HLNCHOAK_00060 1.3e-10
HLNCHOAK_00061 1.1e-116
HLNCHOAK_00063 2.1e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
HLNCHOAK_00064 5e-17
HLNCHOAK_00066 4e-100 S aspartate phosphatase
HLNCHOAK_00068 6.9e-19
HLNCHOAK_00069 3.3e-28 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLNCHOAK_00070 1.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HLNCHOAK_00071 1.2e-100 yokH G SMI1 / KNR4 family
HLNCHOAK_00072 1.5e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HLNCHOAK_00073 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HLNCHOAK_00074 1e-120 yobQ K helix_turn_helix, arabinose operon control protein
HLNCHOAK_00075 6.5e-139 yobR 2.3.1.1 J FR47-like protein
HLNCHOAK_00076 9e-96 yobS K Transcriptional regulator
HLNCHOAK_00077 4.7e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HLNCHOAK_00078 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
HLNCHOAK_00079 1.3e-171 yobV K WYL domain
HLNCHOAK_00080 1e-93 yobW
HLNCHOAK_00081 1e-51 czrA K transcriptional
HLNCHOAK_00082 5.8e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HLNCHOAK_00083 1.5e-92 yozB S membrane
HLNCHOAK_00084 1.9e-144
HLNCHOAK_00085 6.1e-93 yocC
HLNCHOAK_00086 4.2e-186 yocD 3.4.17.13 V peptidase S66
HLNCHOAK_00087 1.2e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HLNCHOAK_00088 7.1e-198 desK 2.7.13.3 T Histidine kinase
HLNCHOAK_00089 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLNCHOAK_00091 6e-112 yocH CBM50 M COG1388 FOG LysM repeat
HLNCHOAK_00092 0.0 recQ 3.6.4.12 L DNA helicase
HLNCHOAK_00093 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLNCHOAK_00094 7.4e-83 dksA T general stress protein
HLNCHOAK_00095 8.4e-54 yocL
HLNCHOAK_00096 8.3e-29
HLNCHOAK_00097 6.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HLNCHOAK_00098 1.1e-40 yozN
HLNCHOAK_00099 1.9e-36 yocN
HLNCHOAK_00100 4.2e-56 yozO S Bacterial PH domain
HLNCHOAK_00101 2.7e-31 yozC
HLNCHOAK_00102 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HLNCHOAK_00103 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HLNCHOAK_00104 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
HLNCHOAK_00105 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HLNCHOAK_00106 2.1e-166 yocS S -transporter
HLNCHOAK_00107 5.3e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HLNCHOAK_00108 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HLNCHOAK_00109 0.0 yojO P Von Willebrand factor
HLNCHOAK_00110 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
HLNCHOAK_00111 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HLNCHOAK_00112 1.3e-197 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HLNCHOAK_00113 3.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HLNCHOAK_00114 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLNCHOAK_00116 1.6e-244 norM V Multidrug efflux pump
HLNCHOAK_00117 7.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLNCHOAK_00118 3.7e-125 yojG S deacetylase
HLNCHOAK_00119 2.2e-60 yojF S Protein of unknown function (DUF1806)
HLNCHOAK_00120 1.5e-43
HLNCHOAK_00121 5.6e-161 rarD S -transporter
HLNCHOAK_00122 8.6e-65 yozR S COG0071 Molecular chaperone (small heat shock protein)
HLNCHOAK_00123 2.6e-09
HLNCHOAK_00124 1e-203 gntP EG COG2610 H gluconate symporter and related permeases
HLNCHOAK_00125 4.7e-64 yodA S tautomerase
HLNCHOAK_00126 4.4e-55 yodB K transcriptional
HLNCHOAK_00127 1.4e-107 yodC C nitroreductase
HLNCHOAK_00128 3.8e-113 mhqD S Carboxylesterase
HLNCHOAK_00129 2.9e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
HLNCHOAK_00130 5.3e-27 S Protein of unknown function (DUF3311)
HLNCHOAK_00131 5.1e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLNCHOAK_00132 3.4e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HLNCHOAK_00133 2.4e-127 yodH Q Methyltransferase
HLNCHOAK_00134 1.5e-23 yodI
HLNCHOAK_00135 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HLNCHOAK_00136 1.2e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HLNCHOAK_00137 5.3e-09
HLNCHOAK_00138 3.6e-54 yodL S YodL-like
HLNCHOAK_00139 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
HLNCHOAK_00140 2.8e-24 yozD S YozD-like protein
HLNCHOAK_00142 6e-123 yodN
HLNCHOAK_00143 1.4e-36 yozE S Belongs to the UPF0346 family
HLNCHOAK_00144 2.9e-47 yokU S YokU-like protein, putative antitoxin
HLNCHOAK_00145 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HLNCHOAK_00146 8.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HLNCHOAK_00147 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
HLNCHOAK_00148 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HLNCHOAK_00149 1.9e-124 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HLNCHOAK_00150 2.6e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLNCHOAK_00152 1.7e-142 yiiD K acetyltransferase
HLNCHOAK_00153 2.6e-252 cgeD M maturation of the outermost layer of the spore
HLNCHOAK_00154 4.5e-38 cgeC
HLNCHOAK_00155 8.2e-64 cgeA
HLNCHOAK_00156 7e-178 cgeB S Spore maturation protein
HLNCHOAK_00157 6.4e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HLNCHOAK_00158 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HLNCHOAK_00159 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HLNCHOAK_00160 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLNCHOAK_00161 1.6e-70 ypoP K transcriptional
HLNCHOAK_00162 5.8e-223 mepA V MATE efflux family protein
HLNCHOAK_00163 5.5e-29 ypmT S Uncharacterized ympT
HLNCHOAK_00164 1.1e-98 ypmS S protein conserved in bacteria
HLNCHOAK_00165 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HLNCHOAK_00166 7.1e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HLNCHOAK_00167 3.4e-39 ypmP S Protein of unknown function (DUF2535)
HLNCHOAK_00168 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HLNCHOAK_00169 1.6e-185 pspF K Transcriptional regulator
HLNCHOAK_00170 1.2e-109 hlyIII S protein, Hemolysin III
HLNCHOAK_00171 3.8e-108 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HLNCHOAK_00172 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLNCHOAK_00173 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HLNCHOAK_00174 7.8e-114 ypjP S YpjP-like protein
HLNCHOAK_00175 1e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HLNCHOAK_00176 1.1e-74 yphP S Belongs to the UPF0403 family
HLNCHOAK_00177 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HLNCHOAK_00178 9.8e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
HLNCHOAK_00179 5.8e-109 ypgQ S phosphohydrolase
HLNCHOAK_00180 2.6e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HLNCHOAK_00181 1.4e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HLNCHOAK_00182 3.5e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HLNCHOAK_00183 1e-30 cspD K Cold-shock protein
HLNCHOAK_00184 3.8e-16 degR
HLNCHOAK_00185 8.1e-31 S Protein of unknown function (DUF2564)
HLNCHOAK_00186 4.1e-29 ypeQ S Zinc-finger
HLNCHOAK_00187 1.9e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HLNCHOAK_00188 6.3e-120 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HLNCHOAK_00189 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
HLNCHOAK_00191 4.4e-166 polA 2.7.7.7 L 5'3' exonuclease
HLNCHOAK_00192 2e-07
HLNCHOAK_00193 8.5e-38 ypbS S Protein of unknown function (DUF2533)
HLNCHOAK_00194 0.0 ypbR S Dynamin family
HLNCHOAK_00195 5.1e-87 ypbQ S protein conserved in bacteria
HLNCHOAK_00196 4.8e-207 bcsA Q Naringenin-chalcone synthase
HLNCHOAK_00197 1.1e-226 pbuX F xanthine
HLNCHOAK_00198 2.4e-96 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLNCHOAK_00199 6.7e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HLNCHOAK_00200 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HLNCHOAK_00201 1e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HLNCHOAK_00202 1.2e-185 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HLNCHOAK_00203 1.5e-186 ptxS K transcriptional
HLNCHOAK_00204 3.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HLNCHOAK_00205 2.3e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_00206 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HLNCHOAK_00208 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HLNCHOAK_00209 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLNCHOAK_00210 2.8e-91 ypsA S Belongs to the UPF0398 family
HLNCHOAK_00211 2.8e-235 yprB L RNase_H superfamily
HLNCHOAK_00212 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HLNCHOAK_00213 1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HLNCHOAK_00214 3.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
HLNCHOAK_00215 1.2e-48 yppG S YppG-like protein
HLNCHOAK_00217 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
HLNCHOAK_00220 2.9e-184 yppC S Protein of unknown function (DUF2515)
HLNCHOAK_00221 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLNCHOAK_00222 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HLNCHOAK_00223 1.2e-91 ypoC
HLNCHOAK_00224 3.7e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLNCHOAK_00225 5.7e-129 dnaD L DNA replication protein DnaD
HLNCHOAK_00226 2.9e-251 asnS 6.1.1.22 J asparaginyl-tRNA
HLNCHOAK_00227 1.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HLNCHOAK_00228 6.4e-79 ypmB S protein conserved in bacteria
HLNCHOAK_00229 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HLNCHOAK_00230 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HLNCHOAK_00231 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HLNCHOAK_00232 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HLNCHOAK_00233 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HLNCHOAK_00234 3.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLNCHOAK_00235 1e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLNCHOAK_00236 4.1e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HLNCHOAK_00237 1.3e-128 bshB1 S proteins, LmbE homologs
HLNCHOAK_00238 2.1e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HLNCHOAK_00239 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLNCHOAK_00240 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HLNCHOAK_00241 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HLNCHOAK_00242 1e-142 ypjB S sporulation protein
HLNCHOAK_00243 4.4e-98 ypjA S membrane
HLNCHOAK_00244 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HLNCHOAK_00245 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HLNCHOAK_00246 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HLNCHOAK_00247 4.2e-77 ypiF S Protein of unknown function (DUF2487)
HLNCHOAK_00248 2.8e-99 ypiB S Belongs to the UPF0302 family
HLNCHOAK_00249 1.5e-231 S COG0457 FOG TPR repeat
HLNCHOAK_00250 1.1e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HLNCHOAK_00251 9.9e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HLNCHOAK_00252 1.1e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HLNCHOAK_00253 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HLNCHOAK_00254 7.6e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HLNCHOAK_00255 5.1e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HLNCHOAK_00256 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HLNCHOAK_00257 3.9e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HLNCHOAK_00258 5.6e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLNCHOAK_00259 3.9e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HLNCHOAK_00260 9.3e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HLNCHOAK_00261 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HLNCHOAK_00262 4.2e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HLNCHOAK_00263 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HLNCHOAK_00264 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HLNCHOAK_00265 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLNCHOAK_00266 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HLNCHOAK_00267 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HLNCHOAK_00268 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HLNCHOAK_00269 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLNCHOAK_00270 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HLNCHOAK_00271 1.1e-135 yphF
HLNCHOAK_00272 1.6e-18 yphE S Protein of unknown function (DUF2768)
HLNCHOAK_00273 3.6e-180 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HLNCHOAK_00274 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HLNCHOAK_00275 1.6e-28 ypzH
HLNCHOAK_00276 3.3e-161 seaA S YIEGIA protein
HLNCHOAK_00277 3.9e-102 yphA
HLNCHOAK_00278 1e-07 S YpzI-like protein
HLNCHOAK_00279 8.4e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLNCHOAK_00280 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HLNCHOAK_00281 8.9e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HLNCHOAK_00282 5e-21 S Family of unknown function (DUF5359)
HLNCHOAK_00283 6.6e-111 ypfA M Flagellar protein YcgR
HLNCHOAK_00284 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HLNCHOAK_00285 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HLNCHOAK_00286 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HLNCHOAK_00287 3.3e-175 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HLNCHOAK_00288 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HLNCHOAK_00289 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HLNCHOAK_00290 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
HLNCHOAK_00291 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HLNCHOAK_00292 1.7e-78 ypbE M Lysin motif
HLNCHOAK_00293 5.3e-99 ypbD S metal-dependent membrane protease
HLNCHOAK_00294 7.8e-285 recQ 3.6.4.12 L DNA helicase
HLNCHOAK_00295 5.1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
HLNCHOAK_00296 4.7e-41 fer C Ferredoxin
HLNCHOAK_00297 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLNCHOAK_00298 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLNCHOAK_00299 2.1e-132 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HLNCHOAK_00300 1.3e-196 rsiX
HLNCHOAK_00301 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HLNCHOAK_00302 0.0 resE 2.7.13.3 T Histidine kinase
HLNCHOAK_00303 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_00304 8.8e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HLNCHOAK_00305 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HLNCHOAK_00306 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HLNCHOAK_00307 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HLNCHOAK_00308 1.9e-87 spmB S Spore maturation protein
HLNCHOAK_00309 3.5e-103 spmA S Spore maturation protein
HLNCHOAK_00310 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HLNCHOAK_00311 7.6e-97 ypuI S Protein of unknown function (DUF3907)
HLNCHOAK_00312 3.5e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLNCHOAK_00313 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLNCHOAK_00314 3e-90 ypuF S Domain of unknown function (DUF309)
HLNCHOAK_00315 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLNCHOAK_00316 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HLNCHOAK_00317 2.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HLNCHOAK_00318 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
HLNCHOAK_00319 8.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLNCHOAK_00320 7.8e-55 ypuD
HLNCHOAK_00321 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HLNCHOAK_00322 7.3e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HLNCHOAK_00324 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLNCHOAK_00325 8.1e-149 ypuA S Secreted protein
HLNCHOAK_00326 2.6e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLNCHOAK_00327 1.4e-273 spoVAF EG Stage V sporulation protein AF
HLNCHOAK_00328 1.4e-110 spoVAEA S stage V sporulation protein
HLNCHOAK_00329 2.2e-57 spoVAEB S stage V sporulation protein
HLNCHOAK_00330 4.5e-191 spoVAD I Stage V sporulation protein AD
HLNCHOAK_00331 2.3e-78 spoVAC S stage V sporulation protein AC
HLNCHOAK_00332 1e-67 spoVAB S Stage V sporulation protein AB
HLNCHOAK_00333 9.6e-112 spoVAA S Stage V sporulation protein AA
HLNCHOAK_00334 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLNCHOAK_00335 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HLNCHOAK_00336 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HLNCHOAK_00337 5.3e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HLNCHOAK_00338 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HLNCHOAK_00339 1.1e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HLNCHOAK_00340 5.9e-155 xerD L recombinase XerD
HLNCHOAK_00341 1.4e-36 S Protein of unknown function (DUF4227)
HLNCHOAK_00342 2.4e-80 fur P Belongs to the Fur family
HLNCHOAK_00343 8.2e-106 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HLNCHOAK_00344 3.2e-30 yqkK
HLNCHOAK_00345 1.6e-241 mleA 1.1.1.38 C malic enzyme
HLNCHOAK_00346 3.5e-234 mleN C Na H antiporter
HLNCHOAK_00347 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HLNCHOAK_00348 8e-185 ansA 3.5.1.1 EJ L-asparaginase
HLNCHOAK_00349 4.5e-58 ansR K Transcriptional regulator
HLNCHOAK_00350 2.4e-220 yqxK 3.6.4.12 L DNA helicase
HLNCHOAK_00351 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HLNCHOAK_00353 4.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HLNCHOAK_00354 3.1e-12 yqkE S Protein of unknown function (DUF3886)
HLNCHOAK_00355 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HLNCHOAK_00356 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HLNCHOAK_00357 2.8e-54 yqkB S Belongs to the HesB IscA family
HLNCHOAK_00358 6.3e-193 yqkA K GrpB protein
HLNCHOAK_00359 2.6e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HLNCHOAK_00360 3.6e-87 yqjY K acetyltransferase
HLNCHOAK_00361 5.7e-50 S YolD-like protein
HLNCHOAK_00362 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLNCHOAK_00364 3.8e-224 yqjV G Major Facilitator Superfamily
HLNCHOAK_00366 3.4e-43 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLNCHOAK_00367 2e-20 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLNCHOAK_00368 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HLNCHOAK_00369 1.6e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HLNCHOAK_00370 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_00371 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HLNCHOAK_00372 1.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLNCHOAK_00373 0.0 rocB E arginine degradation protein
HLNCHOAK_00374 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HLNCHOAK_00375 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLNCHOAK_00376 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HLNCHOAK_00377 2.5e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLNCHOAK_00378 8.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLNCHOAK_00379 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLNCHOAK_00380 5.2e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLNCHOAK_00381 6.2e-24 yqzJ
HLNCHOAK_00382 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLNCHOAK_00383 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
HLNCHOAK_00384 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HLNCHOAK_00385 9.5e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HLNCHOAK_00386 6.6e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HLNCHOAK_00388 5.2e-98 yqjB S protein conserved in bacteria
HLNCHOAK_00389 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
HLNCHOAK_00390 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HLNCHOAK_00391 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HLNCHOAK_00392 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HLNCHOAK_00393 9.3e-77 yqiW S Belongs to the UPF0403 family
HLNCHOAK_00394 1.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HLNCHOAK_00395 7.9e-208 norA EGP Major facilitator Superfamily
HLNCHOAK_00396 1.7e-151 bmrR K helix_turn_helix, mercury resistance
HLNCHOAK_00397 7.3e-223 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLNCHOAK_00398 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLNCHOAK_00399 4.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLNCHOAK_00400 4.9e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLNCHOAK_00401 6e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HLNCHOAK_00402 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HLNCHOAK_00403 7.3e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HLNCHOAK_00404 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HLNCHOAK_00405 4e-34 yqzF S Protein of unknown function (DUF2627)
HLNCHOAK_00406 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HLNCHOAK_00407 1.1e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HLNCHOAK_00408 4.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HLNCHOAK_00409 2e-211 mmgC I acyl-CoA dehydrogenase
HLNCHOAK_00410 3.7e-154 hbdA 1.1.1.157 I Dehydrogenase
HLNCHOAK_00411 8.5e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
HLNCHOAK_00412 1.4e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HLNCHOAK_00413 6e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HLNCHOAK_00414 6e-27
HLNCHOAK_00415 1.8e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HLNCHOAK_00417 7.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HLNCHOAK_00418 1e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
HLNCHOAK_00419 2.1e-305 recN L May be involved in recombinational repair of damaged DNA
HLNCHOAK_00420 1.1e-77 argR K Regulates arginine biosynthesis genes
HLNCHOAK_00421 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HLNCHOAK_00422 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLNCHOAK_00423 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HLNCHOAK_00424 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLNCHOAK_00425 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLNCHOAK_00426 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLNCHOAK_00427 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLNCHOAK_00428 2.1e-67 yqhY S protein conserved in bacteria
HLNCHOAK_00429 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HLNCHOAK_00430 4.4e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLNCHOAK_00431 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HLNCHOAK_00432 2.2e-109 spoIIIAG S stage III sporulation protein AG
HLNCHOAK_00433 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HLNCHOAK_00434 1.3e-197 spoIIIAE S stage III sporulation protein AE
HLNCHOAK_00435 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HLNCHOAK_00436 7.6e-29 spoIIIAC S stage III sporulation protein AC
HLNCHOAK_00437 1.6e-83 spoIIIAB S Stage III sporulation protein
HLNCHOAK_00438 4e-170 spoIIIAA S stage III sporulation protein AA
HLNCHOAK_00439 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HLNCHOAK_00440 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLNCHOAK_00441 3.7e-172 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HLNCHOAK_00442 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HLNCHOAK_00443 2.3e-93 yqhR S Conserved membrane protein YqhR
HLNCHOAK_00444 3e-173 yqhQ S Protein of unknown function (DUF1385)
HLNCHOAK_00445 2.2e-61 yqhP
HLNCHOAK_00446 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
HLNCHOAK_00447 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HLNCHOAK_00448 1.3e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HLNCHOAK_00449 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HLNCHOAK_00450 1.2e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLNCHOAK_00451 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLNCHOAK_00452 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HLNCHOAK_00453 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HLNCHOAK_00454 1e-150 yqhG S Bacterial protein YqhG of unknown function
HLNCHOAK_00455 3.6e-24 sinI S Anti-repressor SinI
HLNCHOAK_00456 1e-54 sinR K transcriptional
HLNCHOAK_00457 8.6e-142 tasA S Cell division protein FtsN
HLNCHOAK_00458 7.4e-58 sipW 3.4.21.89 U Signal peptidase
HLNCHOAK_00459 1.3e-110 yqxM
HLNCHOAK_00460 2.6e-52 yqzG S Protein of unknown function (DUF3889)
HLNCHOAK_00461 5.2e-26 yqzE S YqzE-like protein
HLNCHOAK_00462 1.2e-43 S ComG operon protein 7
HLNCHOAK_00463 2e-35 comGF U Putative Competence protein ComGF
HLNCHOAK_00464 3.1e-59 comGE
HLNCHOAK_00465 7.7e-68 gspH NU protein transport across the cell outer membrane
HLNCHOAK_00466 1.4e-47 comGC U Required for transformation and DNA binding
HLNCHOAK_00467 8.7e-174 comGB NU COG1459 Type II secretory pathway, component PulF
HLNCHOAK_00468 1.5e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HLNCHOAK_00470 5.2e-173 corA P Mg2 transporter protein
HLNCHOAK_00471 4.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HLNCHOAK_00472 3.5e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLNCHOAK_00474 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HLNCHOAK_00475 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HLNCHOAK_00476 8e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HLNCHOAK_00477 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HLNCHOAK_00478 6.9e-50 yqgV S Thiamine-binding protein
HLNCHOAK_00479 4.3e-197 yqgU
HLNCHOAK_00480 2.7e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HLNCHOAK_00481 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HLNCHOAK_00482 3.4e-180 glcK 2.7.1.2 G Glucokinase
HLNCHOAK_00483 1.5e-32 yqgQ S Protein conserved in bacteria
HLNCHOAK_00484 4.6e-248 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HLNCHOAK_00485 2.5e-09 yqgO
HLNCHOAK_00486 2.8e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLNCHOAK_00487 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HLNCHOAK_00488 9.3e-195 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HLNCHOAK_00490 9.2e-51 yqzD
HLNCHOAK_00491 2.1e-71 yqzC S YceG-like family
HLNCHOAK_00492 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLNCHOAK_00493 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLNCHOAK_00494 2.2e-157 pstA P Phosphate transport system permease
HLNCHOAK_00495 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HLNCHOAK_00496 7.6e-150 pstS P Phosphate
HLNCHOAK_00497 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HLNCHOAK_00498 2.5e-231 yqgE EGP Major facilitator superfamily
HLNCHOAK_00499 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HLNCHOAK_00500 4e-73 yqgC S protein conserved in bacteria
HLNCHOAK_00501 1.2e-132 yqgB S Protein of unknown function (DUF1189)
HLNCHOAK_00502 5e-75 yqgA
HLNCHOAK_00503 5.8e-46 yqfZ M LysM domain
HLNCHOAK_00504 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HLNCHOAK_00505 4.3e-62 yqfX S membrane
HLNCHOAK_00506 4.6e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HLNCHOAK_00507 4.2e-77 zur P Belongs to the Fur family
HLNCHOAK_00508 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HLNCHOAK_00509 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HLNCHOAK_00510 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HLNCHOAK_00511 2.5e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLNCHOAK_00512 1.9e-13 yqfQ S YqfQ-like protein
HLNCHOAK_00513 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HLNCHOAK_00514 1.3e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLNCHOAK_00515 3e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
HLNCHOAK_00516 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HLNCHOAK_00517 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLNCHOAK_00518 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLNCHOAK_00519 4.5e-88 yaiI S Belongs to the UPF0178 family
HLNCHOAK_00520 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HLNCHOAK_00521 4.5e-112 ccpN K CBS domain
HLNCHOAK_00522 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HLNCHOAK_00523 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HLNCHOAK_00524 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
HLNCHOAK_00525 8.4e-19 S YqzL-like protein
HLNCHOAK_00526 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLNCHOAK_00527 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HLNCHOAK_00528 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HLNCHOAK_00529 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLNCHOAK_00530 0.0 yqfF S membrane-associated HD superfamily hydrolase
HLNCHOAK_00532 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HLNCHOAK_00533 9e-199 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HLNCHOAK_00534 2.7e-45 yqfC S sporulation protein YqfC
HLNCHOAK_00535 4.3e-23 yqfB
HLNCHOAK_00536 4.3e-122 yqfA S UPF0365 protein
HLNCHOAK_00537 3.2e-226 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HLNCHOAK_00538 2.5e-61 yqeY S Yqey-like protein
HLNCHOAK_00539 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HLNCHOAK_00540 1.1e-156 yqeW P COG1283 Na phosphate symporter
HLNCHOAK_00541 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HLNCHOAK_00542 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLNCHOAK_00543 3e-173 prmA J Methylates ribosomal protein L11
HLNCHOAK_00544 1.2e-181 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLNCHOAK_00545 0.0 dnaK O Heat shock 70 kDa protein
HLNCHOAK_00546 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLNCHOAK_00547 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLNCHOAK_00548 2.9e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
HLNCHOAK_00549 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLNCHOAK_00550 6.8e-51 yqxA S Protein of unknown function (DUF3679)
HLNCHOAK_00551 1.5e-222 spoIIP M stage II sporulation protein P
HLNCHOAK_00552 1.5e-203 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HLNCHOAK_00553 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HLNCHOAK_00554 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HLNCHOAK_00555 4.1e-15 S YqzM-like protein
HLNCHOAK_00556 0.0 comEC S Competence protein ComEC
HLNCHOAK_00557 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HLNCHOAK_00558 3.5e-98 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HLNCHOAK_00559 5.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLNCHOAK_00560 4.2e-138 yqeM Q Methyltransferase
HLNCHOAK_00561 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLNCHOAK_00562 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HLNCHOAK_00563 3.8e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLNCHOAK_00564 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HLNCHOAK_00565 6.6e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLNCHOAK_00566 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HLNCHOAK_00567 5.3e-95 yqeG S hydrolase of the HAD superfamily
HLNCHOAK_00569 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HLNCHOAK_00570 1.3e-134 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HLNCHOAK_00571 1.2e-104 yqeD S SNARE associated Golgi protein
HLNCHOAK_00572 3e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HLNCHOAK_00573 5.7e-132 yqeB
HLNCHOAK_00574 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HLNCHOAK_00575 9.3e-278 cisA2 L Recombinase
HLNCHOAK_00578 9.9e-19 S SMI1-KNR4 cell-wall
HLNCHOAK_00579 7.2e-87 K Transcriptional regulator C-terminal region
HLNCHOAK_00580 1.7e-178 S X-Pro dipeptidyl-peptidase (S15 family)
HLNCHOAK_00581 5.6e-11 crh G Phosphocarrier protein Chr
HLNCHOAK_00582 1.8e-109 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_00583 2.6e-158 EGP Major facilitator Superfamily
HLNCHOAK_00584 3.4e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HLNCHOAK_00585 7.4e-56 K transcriptional
HLNCHOAK_00586 9.7e-111 nfsA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HLNCHOAK_00588 1.2e-64 S response regulator aspartate phosphatase
HLNCHOAK_00590 9.8e-28
HLNCHOAK_00591 4.8e-272 A Pre-toxin TG
HLNCHOAK_00592 6.4e-102 S Suppressor of fused protein (SUFU)
HLNCHOAK_00593 9.9e-26 gepA S Protein of unknown function (DUF4065)
HLNCHOAK_00595 5.5e-123 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HLNCHOAK_00596 5.8e-68 S Bacteriophage holin family
HLNCHOAK_00597 4.2e-161 xepA
HLNCHOAK_00598 4.3e-19
HLNCHOAK_00599 4.6e-52 xkdW S XkdW protein
HLNCHOAK_00600 6.1e-218
HLNCHOAK_00601 4e-38
HLNCHOAK_00602 5.6e-98 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HLNCHOAK_00603 1.7e-185 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HLNCHOAK_00604 1.9e-66 xkdS S Protein of unknown function (DUF2634)
HLNCHOAK_00605 7.2e-32 xkdR S Protein of unknown function (DUF2577)
HLNCHOAK_00606 3.9e-176 yqbQ 3.2.1.96 G NLP P60 protein
HLNCHOAK_00607 2.1e-110 xkdP S Lysin motif
HLNCHOAK_00608 0.0 xkdO L Transglycosylase SLT domain
HLNCHOAK_00609 6.2e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
HLNCHOAK_00610 3e-75 xkdM S Phage tail tube protein
HLNCHOAK_00611 2.2e-252 xkdK S Phage tail sheath C-terminal domain
HLNCHOAK_00612 2.7e-25
HLNCHOAK_00613 1.3e-75
HLNCHOAK_00614 6.7e-87 S Bacteriophage HK97-gp10, putative tail-component
HLNCHOAK_00615 7.7e-61 yqbH S Domain of unknown function (DUF3599)
HLNCHOAK_00616 2.1e-67 S Protein of unknown function (DUF3199)
HLNCHOAK_00617 3.1e-50 S YqbF, hypothetical protein domain
HLNCHOAK_00618 7.1e-167 xkdG S Phage capsid family
HLNCHOAK_00619 1.7e-118 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HLNCHOAK_00620 6e-07
HLNCHOAK_00621 4e-154 S Phage Mu protein F like protein
HLNCHOAK_00622 2.4e-289 yqbA S portal protein
HLNCHOAK_00623 1.3e-246 S phage terminase, large subunit
HLNCHOAK_00624 4e-101 yqaS L DNA packaging
HLNCHOAK_00627 6.2e-76 L Transposase
HLNCHOAK_00629 1.4e-18 wapA M RHS family
HLNCHOAK_00630 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
HLNCHOAK_00631 4.7e-73 rusA L Endodeoxyribonuclease RusA
HLNCHOAK_00633 3.3e-163 xkdC L IstB-like ATP binding protein
HLNCHOAK_00634 4.6e-118 3.1.3.16 L DnaD domain protein
HLNCHOAK_00635 1.3e-151 recT L RecT family
HLNCHOAK_00636 2.7e-174 yqaJ L YqaJ-like viral recombinase domain
HLNCHOAK_00640 4.4e-103
HLNCHOAK_00642 9.1e-18 K Helix-turn-helix XRE-family like proteins
HLNCHOAK_00643 1.1e-32 K sequence-specific DNA binding
HLNCHOAK_00644 1.9e-42 cdo C cysteine dioxygenase type I
HLNCHOAK_00645 1.7e-93 yqaB E IrrE N-terminal-like domain
HLNCHOAK_00646 2.6e-59 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLNCHOAK_00647 3.3e-12 cisA2 L Recombinase
HLNCHOAK_00648 2e-68 psiE S Protein PsiE homolog
HLNCHOAK_00649 1.7e-235 yrkQ T Histidine kinase
HLNCHOAK_00650 4.1e-127 T Transcriptional regulator
HLNCHOAK_00651 2.6e-222 yrkO P Protein of unknown function (DUF418)
HLNCHOAK_00652 2.3e-104 yrkN K Acetyltransferase (GNAT) family
HLNCHOAK_00653 1.5e-97 ywrO S Flavodoxin-like fold
HLNCHOAK_00654 2.8e-79 S Protein of unknown function with HXXEE motif
HLNCHOAK_00655 6.8e-115 yrkJ S membrane transporter protein
HLNCHOAK_00656 9.2e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HLNCHOAK_00657 1.9e-211 yrkH P Rhodanese Homology Domain
HLNCHOAK_00659 1.2e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
HLNCHOAK_00660 2.5e-83 yrkE O DsrE/DsrF/DrsH-like family
HLNCHOAK_00661 7.8e-39 yrkD S protein conserved in bacteria
HLNCHOAK_00662 7.9e-105 yrkC G Cupin domain
HLNCHOAK_00663 2.1e-146 bltR K helix_turn_helix, mercury resistance
HLNCHOAK_00664 1.1e-209 blt EGP Major facilitator Superfamily
HLNCHOAK_00665 9.1e-83 bltD 2.3.1.57 K FR47-like protein
HLNCHOAK_00666 9.7e-231 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HLNCHOAK_00667 8.7e-16 S YrzO-like protein
HLNCHOAK_00668 6e-169 yrdR EG EamA-like transporter family
HLNCHOAK_00669 3.9e-159 yrdQ K Transcriptional regulator
HLNCHOAK_00670 8.6e-198 trkA P Oxidoreductase
HLNCHOAK_00671 7.7e-153 czcD P COG1230 Co Zn Cd efflux system component
HLNCHOAK_00672 1.5e-16 yodA S tautomerase
HLNCHOAK_00673 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
HLNCHOAK_00674 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HLNCHOAK_00675 9.6e-138 azlC E AzlC protein
HLNCHOAK_00676 5.3e-78 bkdR K helix_turn_helix ASNC type
HLNCHOAK_00677 2.6e-40 yrdF K ribonuclease inhibitor
HLNCHOAK_00678 6.1e-227 cypA C Cytochrome P450
HLNCHOAK_00679 9.1e-10 K Acetyltransferase (GNAT) family
HLNCHOAK_00680 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
HLNCHOAK_00681 6.1e-56 S Protein of unknown function (DUF2568)
HLNCHOAK_00683 6.4e-90 yrdA S DinB family
HLNCHOAK_00684 5.1e-164 aadK G Streptomycin adenylyltransferase
HLNCHOAK_00685 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HLNCHOAK_00686 3.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HLNCHOAK_00687 3.7e-40 yrpD S Domain of unknown function, YrpD
HLNCHOAK_00688 1.4e-66 yrpD S Domain of unknown function, YrpD
HLNCHOAK_00689 1.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
HLNCHOAK_00691 2.8e-209 rbtT P Major Facilitator Superfamily
HLNCHOAK_00692 2.4e-112 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_00693 3.8e-152 2.2.1.1 G Transketolase, pyrimidine binding domain
HLNCHOAK_00694 5.2e-137 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
HLNCHOAK_00696 1.4e-214 yfjF U Belongs to the major facilitator superfamily
HLNCHOAK_00697 5.1e-65 napB K MarR family transcriptional regulator
HLNCHOAK_00698 6.6e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HLNCHOAK_00699 2.7e-94 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HLNCHOAK_00700 1.9e-186 yrpG C Aldo/keto reductase family
HLNCHOAK_00701 7.5e-223 yraO C Citrate transporter
HLNCHOAK_00702 3.7e-162 yraN K Transcriptional regulator
HLNCHOAK_00703 6.5e-204 yraM S PrpF protein
HLNCHOAK_00704 1.4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HLNCHOAK_00705 3.8e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLNCHOAK_00706 2.6e-149 S Alpha beta hydrolase
HLNCHOAK_00707 1.7e-60 T sh3 domain protein
HLNCHOAK_00708 2.4e-61 T sh3 domain protein
HLNCHOAK_00709 1.3e-66 E Glyoxalase-like domain
HLNCHOAK_00710 3.4e-36 yraG
HLNCHOAK_00711 6.4e-63 yraF M Spore coat protein
HLNCHOAK_00712 1.6e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HLNCHOAK_00713 7.5e-26 yraE
HLNCHOAK_00714 1.2e-48 yraD M Spore coat protein
HLNCHOAK_00715 4.3e-47 yraB K helix_turn_helix, mercury resistance
HLNCHOAK_00716 2.1e-196 adhA 1.1.1.1 C alcohol dehydrogenase
HLNCHOAK_00717 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HLNCHOAK_00718 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HLNCHOAK_00719 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HLNCHOAK_00720 9.9e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HLNCHOAK_00721 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HLNCHOAK_00722 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
HLNCHOAK_00723 0.0 levR K PTS system fructose IIA component
HLNCHOAK_00724 4.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HLNCHOAK_00725 1.8e-105 yrhP E LysE type translocator
HLNCHOAK_00726 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
HLNCHOAK_00727 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HLNCHOAK_00728 3.6e-149 rsiV S Protein of unknown function (DUF3298)
HLNCHOAK_00729 0.0 yrhL I Acyltransferase family
HLNCHOAK_00730 1.2e-43 yrhK S YrhK-like protein
HLNCHOAK_00731 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HLNCHOAK_00732 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HLNCHOAK_00733 2.8e-91 yrhH Q methyltransferase
HLNCHOAK_00736 1.8e-142 focA P Formate nitrite
HLNCHOAK_00737 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
HLNCHOAK_00738 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HLNCHOAK_00739 2.4e-78 yrhD S Protein of unknown function (DUF1641)
HLNCHOAK_00740 4.6e-35 yrhC S YrhC-like protein
HLNCHOAK_00741 1.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HLNCHOAK_00742 6.8e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HLNCHOAK_00743 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLNCHOAK_00744 1.4e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HLNCHOAK_00745 1e-25 yrzA S Protein of unknown function (DUF2536)
HLNCHOAK_00746 7.9e-62 yrrS S Protein of unknown function (DUF1510)
HLNCHOAK_00747 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HLNCHOAK_00748 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLNCHOAK_00749 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HLNCHOAK_00750 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HLNCHOAK_00751 4.3e-172 yegQ O Peptidase U32
HLNCHOAK_00752 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
HLNCHOAK_00753 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HLNCHOAK_00754 1.2e-45 yrzB S Belongs to the UPF0473 family
HLNCHOAK_00755 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLNCHOAK_00756 1.7e-41 yrzL S Belongs to the UPF0297 family
HLNCHOAK_00757 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLNCHOAK_00758 7.8e-170 yrrI S AI-2E family transporter
HLNCHOAK_00759 5.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HLNCHOAK_00760 2.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
HLNCHOAK_00761 8e-109 gluC P ABC transporter
HLNCHOAK_00762 7.6e-107 glnP P ABC transporter
HLNCHOAK_00763 8e-08 S Protein of unknown function (DUF3918)
HLNCHOAK_00764 9.8e-31 yrzR
HLNCHOAK_00765 1.2e-82 yrrD S protein conserved in bacteria
HLNCHOAK_00766 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLNCHOAK_00767 1.4e-15 S COG0457 FOG TPR repeat
HLNCHOAK_00768 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLNCHOAK_00769 4.8e-210 iscS 2.8.1.7 E Cysteine desulfurase
HLNCHOAK_00770 1.2e-70 cymR K Transcriptional regulator
HLNCHOAK_00771 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HLNCHOAK_00772 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HLNCHOAK_00773 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HLNCHOAK_00774 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HLNCHOAK_00776 4.4e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
HLNCHOAK_00777 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLNCHOAK_00778 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLNCHOAK_00779 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLNCHOAK_00780 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HLNCHOAK_00781 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HLNCHOAK_00782 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HLNCHOAK_00783 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HLNCHOAK_00784 1.6e-48 yrzD S Post-transcriptional regulator
HLNCHOAK_00785 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLNCHOAK_00786 1.7e-111 yrbG S membrane
HLNCHOAK_00787 1.2e-74 yrzE S Protein of unknown function (DUF3792)
HLNCHOAK_00788 8e-39 yajC U Preprotein translocase subunit YajC
HLNCHOAK_00789 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLNCHOAK_00790 7.5e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HLNCHOAK_00791 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HLNCHOAK_00792 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLNCHOAK_00793 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLNCHOAK_00794 4.8e-93 bofC S BofC C-terminal domain
HLNCHOAK_00795 4.5e-252 csbX EGP Major facilitator Superfamily
HLNCHOAK_00796 3.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HLNCHOAK_00797 1.9e-118 yrzF T serine threonine protein kinase
HLNCHOAK_00799 8.1e-52 S Family of unknown function (DUF5412)
HLNCHOAK_00800 1.3e-260 alsT E Sodium alanine symporter
HLNCHOAK_00801 7.9e-94 yebC K transcriptional regulatory protein
HLNCHOAK_00802 9.1e-18 yebC K transcriptional regulatory protein
HLNCHOAK_00803 1.7e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLNCHOAK_00804 8.3e-157 safA M spore coat assembly protein SafA
HLNCHOAK_00805 4.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HLNCHOAK_00806 2.8e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HLNCHOAK_00807 3.5e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HLNCHOAK_00808 4.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
HLNCHOAK_00809 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HLNCHOAK_00810 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
HLNCHOAK_00811 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HLNCHOAK_00812 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLNCHOAK_00813 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HLNCHOAK_00814 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HLNCHOAK_00815 4.1e-56 ysxB J ribosomal protein
HLNCHOAK_00816 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HLNCHOAK_00817 9.2e-161 spoIVFB S Stage IV sporulation protein
HLNCHOAK_00818 2.5e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HLNCHOAK_00819 8e-143 minD D Belongs to the ParA family
HLNCHOAK_00820 5.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HLNCHOAK_00821 3.2e-84 mreD M shape-determining protein
HLNCHOAK_00822 1.1e-156 mreC M Involved in formation and maintenance of cell shape
HLNCHOAK_00823 1.8e-184 mreB D Rod shape-determining protein MreB
HLNCHOAK_00824 1.3e-125 radC E Belongs to the UPF0758 family
HLNCHOAK_00825 2.8e-102 maf D septum formation protein Maf
HLNCHOAK_00826 3.8e-166 spoIIB S Sporulation related domain
HLNCHOAK_00827 1.4e-125 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HLNCHOAK_00828 2.1e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HLNCHOAK_00829 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLNCHOAK_00830 1.6e-25
HLNCHOAK_00831 2.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HLNCHOAK_00832 4.3e-194 spoVID M stage VI sporulation protein D
HLNCHOAK_00833 8.1e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HLNCHOAK_00834 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HLNCHOAK_00835 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HLNCHOAK_00836 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HLNCHOAK_00837 3e-145 hemX O cytochrome C
HLNCHOAK_00838 5.9e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HLNCHOAK_00839 5.4e-89 ysxD
HLNCHOAK_00840 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HLNCHOAK_00841 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HLNCHOAK_00842 6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HLNCHOAK_00843 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLNCHOAK_00844 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLNCHOAK_00845 1.9e-186 ysoA H Tetratricopeptide repeat
HLNCHOAK_00846 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLNCHOAK_00847 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLNCHOAK_00848 3.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HLNCHOAK_00849 2.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HLNCHOAK_00850 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HLNCHOAK_00851 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HLNCHOAK_00852 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HLNCHOAK_00854 5.7e-77 ysnE K acetyltransferase
HLNCHOAK_00855 6.5e-132 ysnF S protein conserved in bacteria
HLNCHOAK_00857 4.1e-92 ysnB S Phosphoesterase
HLNCHOAK_00858 2.9e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLNCHOAK_00859 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HLNCHOAK_00860 5e-196 gerM S COG5401 Spore germination protein
HLNCHOAK_00861 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HLNCHOAK_00862 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HLNCHOAK_00863 1.8e-167 L Recombinase
HLNCHOAK_00864 9.3e-45 S YolD-like protein
HLNCHOAK_00865 1.2e-58
HLNCHOAK_00867 3e-128 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HLNCHOAK_00868 2.7e-31 xhlB S SPP1 phage holin
HLNCHOAK_00869 1.5e-27 xhlA S Haemolysin XhlA
HLNCHOAK_00870 8.5e-14 xkdX
HLNCHOAK_00872 5.4e-37
HLNCHOAK_00873 3.9e-60
HLNCHOAK_00874 2.3e-106 Z012_12235 S homolog of phage Mu protein gp47
HLNCHOAK_00875 4.8e-23 S Protein of unknown function (DUF2634)
HLNCHOAK_00876 4.7e-23
HLNCHOAK_00877 6.1e-89
HLNCHOAK_00878 1.6e-31
HLNCHOAK_00879 1e-40 3.5.1.28 M LysM domain
HLNCHOAK_00880 8.8e-125 N phage tail tape measure protein
HLNCHOAK_00881 1.7e-13
HLNCHOAK_00882 1.8e-34
HLNCHOAK_00883 6.1e-103 Z012_02110 S Protein of unknown function (DUF3383)
HLNCHOAK_00884 7e-30
HLNCHOAK_00885 1.1e-23
HLNCHOAK_00886 4.4e-46
HLNCHOAK_00887 7.5e-18 S Phage gp6-like head-tail connector protein
HLNCHOAK_00888 4.8e-32 S Phage Mu protein F like protein
HLNCHOAK_00890 1.9e-111 S Phage capsid family
HLNCHOAK_00891 2.2e-65 S Domain of unknown function (DUF4355)
HLNCHOAK_00892 1.7e-156 S Phage portal protein, SPP1 Gp6-like
HLNCHOAK_00893 1.3e-184 ps334 S Terminase-like family
HLNCHOAK_00894 1.8e-80 yqaS L DNA packaging
HLNCHOAK_00895 3.4e-22
HLNCHOAK_00897 2.5e-43
HLNCHOAK_00898 6e-13 K Transcriptional regulator
HLNCHOAK_00900 8.9e-71 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HLNCHOAK_00905 4e-08 S YopX protein
HLNCHOAK_00909 9.3e-27 yqaO S Phage-like element PBSX protein XtrA
HLNCHOAK_00911 6.8e-54 S Protein of unknown function (DUF1064)
HLNCHOAK_00913 1.1e-11 S YopX protein
HLNCHOAK_00915 2.2e-121 xkdC L IstB-like ATP binding protein
HLNCHOAK_00916 8.7e-37 3.1.3.16 L DnaD domain protein
HLNCHOAK_00917 3.4e-69 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HLNCHOAK_00918 5.8e-97
HLNCHOAK_00923 5.4e-69
HLNCHOAK_00924 5.3e-45 S DNA binding
HLNCHOAK_00926 1.2e-14 K Helix-turn-helix XRE-family like proteins
HLNCHOAK_00927 3.1e-23 K sequence-specific DNA binding
HLNCHOAK_00928 8.5e-20
HLNCHOAK_00929 1.2e-48 yqaB E IrrE N-terminal-like domain
HLNCHOAK_00930 1.9e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HLNCHOAK_00931 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HLNCHOAK_00932 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HLNCHOAK_00933 2.4e-107 sdhC C succinate dehydrogenase
HLNCHOAK_00934 1.2e-79 yslB S Protein of unknown function (DUF2507)
HLNCHOAK_00935 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HLNCHOAK_00936 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLNCHOAK_00937 2e-52 trxA O Belongs to the thioredoxin family
HLNCHOAK_00938 2.6e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HLNCHOAK_00940 6e-177 etfA C Electron transfer flavoprotein
HLNCHOAK_00941 4.5e-135 etfB C Electron transfer flavoprotein
HLNCHOAK_00942 1e-134 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HLNCHOAK_00943 4e-99 fadR K Transcriptional regulator
HLNCHOAK_00944 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HLNCHOAK_00945 7.3e-68 yshE S membrane
HLNCHOAK_00946 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLNCHOAK_00947 0.0 polX L COG1796 DNA polymerase IV (family X)
HLNCHOAK_00948 3.9e-85 cvpA S membrane protein, required for colicin V production
HLNCHOAK_00949 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HLNCHOAK_00950 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLNCHOAK_00951 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLNCHOAK_00952 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLNCHOAK_00953 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLNCHOAK_00954 5.8e-32 sspI S Belongs to the SspI family
HLNCHOAK_00955 3.6e-202 ysfB KT regulator
HLNCHOAK_00956 9.7e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
HLNCHOAK_00957 6.2e-257 glcF C Glycolate oxidase
HLNCHOAK_00958 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
HLNCHOAK_00959 0.0 cstA T Carbon starvation protein
HLNCHOAK_00960 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HLNCHOAK_00961 3.4e-144 araQ G transport system permease
HLNCHOAK_00962 1.4e-167 araP G carbohydrate transport
HLNCHOAK_00963 6.2e-254 araN G carbohydrate transport
HLNCHOAK_00964 8e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HLNCHOAK_00965 3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HLNCHOAK_00966 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HLNCHOAK_00967 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HLNCHOAK_00968 7.8e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HLNCHOAK_00969 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HLNCHOAK_00970 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HLNCHOAK_00971 3.5e-67 ysdB S Sigma-w pathway protein YsdB
HLNCHOAK_00972 7.5e-45 ysdA S Membrane
HLNCHOAK_00973 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLNCHOAK_00974 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HLNCHOAK_00975 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLNCHOAK_00977 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HLNCHOAK_00978 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HLNCHOAK_00979 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
HLNCHOAK_00980 0.0 lytS 2.7.13.3 T Histidine kinase
HLNCHOAK_00981 2.8e-148 ysaA S HAD-hyrolase-like
HLNCHOAK_00982 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLNCHOAK_00983 1.4e-158 ytxC S YtxC-like family
HLNCHOAK_00984 4.6e-109 ytxB S SNARE associated Golgi protein
HLNCHOAK_00985 2.5e-172 dnaI L Primosomal protein DnaI
HLNCHOAK_00986 2.2e-265 dnaB L Membrane attachment protein
HLNCHOAK_00987 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLNCHOAK_00988 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HLNCHOAK_00989 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLNCHOAK_00990 4.9e-66 ytcD K Transcriptional regulator
HLNCHOAK_00991 4.6e-203 ytbD EGP Major facilitator Superfamily
HLNCHOAK_00992 8.9e-161 ytbE S reductase
HLNCHOAK_00993 1.3e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLNCHOAK_00994 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HLNCHOAK_00995 3.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLNCHOAK_00996 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLNCHOAK_00997 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HLNCHOAK_00998 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_00999 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HLNCHOAK_01000 4.1e-242 icd 1.1.1.42 C isocitrate
HLNCHOAK_01001 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HLNCHOAK_01002 4.7e-71 yeaL S membrane
HLNCHOAK_01003 2.6e-192 ytvI S sporulation integral membrane protein YtvI
HLNCHOAK_01004 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HLNCHOAK_01005 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HLNCHOAK_01006 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HLNCHOAK_01007 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HLNCHOAK_01008 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLNCHOAK_01009 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HLNCHOAK_01010 0.0 dnaE 2.7.7.7 L DNA polymerase
HLNCHOAK_01011 3.2e-56 ytrH S Sporulation protein YtrH
HLNCHOAK_01012 8.2e-69 ytrI
HLNCHOAK_01013 9.2e-29
HLNCHOAK_01014 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HLNCHOAK_01015 2.4e-47 ytpI S YtpI-like protein
HLNCHOAK_01016 8e-241 ytoI K transcriptional regulator containing CBS domains
HLNCHOAK_01017 1.7e-130 ytkL S Belongs to the UPF0173 family
HLNCHOAK_01018 3.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_01020 6.4e-265 argH 4.3.2.1 E argininosuccinate lyase
HLNCHOAK_01021 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLNCHOAK_01022 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HLNCHOAK_01023 1.8e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLNCHOAK_01024 5.9e-164 ytxK 2.1.1.72 L DNA methylase
HLNCHOAK_01025 5.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLNCHOAK_01026 8.7e-70 ytfJ S Sporulation protein YtfJ
HLNCHOAK_01027 1.2e-110 ytfI S Protein of unknown function (DUF2953)
HLNCHOAK_01028 8.5e-87 yteJ S RDD family
HLNCHOAK_01029 1.1e-178 sppA OU signal peptide peptidase SppA
HLNCHOAK_01030 3.7e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLNCHOAK_01031 0.0 ytcJ S amidohydrolase
HLNCHOAK_01032 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HLNCHOAK_01033 2e-29 sspB S spore protein
HLNCHOAK_01034 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLNCHOAK_01035 1.9e-206 iscS2 2.8.1.7 E Cysteine desulfurase
HLNCHOAK_01036 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HLNCHOAK_01037 1.2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLNCHOAK_01038 3.8e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HLNCHOAK_01039 1e-108 yttP K Transcriptional regulator
HLNCHOAK_01040 5.9e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HLNCHOAK_01041 2.2e-310 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HLNCHOAK_01042 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLNCHOAK_01044 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLNCHOAK_01045 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HLNCHOAK_01046 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HLNCHOAK_01047 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HLNCHOAK_01048 4e-223 acuC BQ histone deacetylase
HLNCHOAK_01049 2e-124 motS N Flagellar motor protein
HLNCHOAK_01050 7.9e-146 motA N flagellar motor
HLNCHOAK_01051 1.7e-182 ccpA K catabolite control protein A
HLNCHOAK_01052 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HLNCHOAK_01053 1.1e-53 ytxJ O Protein of unknown function (DUF2847)
HLNCHOAK_01054 6.6e-17 ytxH S COG4980 Gas vesicle protein
HLNCHOAK_01055 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLNCHOAK_01056 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HLNCHOAK_01057 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HLNCHOAK_01058 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLNCHOAK_01059 9.8e-149 ytpQ S Belongs to the UPF0354 family
HLNCHOAK_01060 1.3e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HLNCHOAK_01061 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HLNCHOAK_01062 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HLNCHOAK_01063 2.2e-51 ytzB S small secreted protein
HLNCHOAK_01064 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HLNCHOAK_01065 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HLNCHOAK_01066 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLNCHOAK_01067 2e-45 ytzH S YtzH-like protein
HLNCHOAK_01068 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HLNCHOAK_01069 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HLNCHOAK_01070 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HLNCHOAK_01071 2.9e-165 ytlQ
HLNCHOAK_01072 3.7e-99 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HLNCHOAK_01073 3.3e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HLNCHOAK_01074 7.1e-272 pepV 3.5.1.18 E Dipeptidase
HLNCHOAK_01075 2.3e-224 pbuO S permease
HLNCHOAK_01076 3.4e-203 ythQ U Bacterial ABC transporter protein EcsB
HLNCHOAK_01077 4.8e-131 ythP V ABC transporter
HLNCHOAK_01078 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HLNCHOAK_01079 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HLNCHOAK_01080 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLNCHOAK_01081 3.1e-231 ytfP S HI0933-like protein
HLNCHOAK_01082 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HLNCHOAK_01083 3.1e-26 yteV S Sporulation protein Cse60
HLNCHOAK_01084 2.2e-114 yteU S Integral membrane protein
HLNCHOAK_01085 1.4e-247 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HLNCHOAK_01086 3.3e-71 yteS G transport
HLNCHOAK_01087 7.3e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HLNCHOAK_01088 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HLNCHOAK_01089 0.0 ytdP K Transcriptional regulator
HLNCHOAK_01090 2.6e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HLNCHOAK_01091 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HLNCHOAK_01092 8.1e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HLNCHOAK_01093 1.2e-219 bioI 1.14.14.46 C Cytochrome P450
HLNCHOAK_01094 2.9e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HLNCHOAK_01095 3.8e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HLNCHOAK_01096 4.3e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HLNCHOAK_01097 1.5e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HLNCHOAK_01098 3.8e-139 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HLNCHOAK_01099 9.2e-172 ytaP S Acetyl xylan esterase (AXE1)
HLNCHOAK_01100 1.9e-189 msmR K Transcriptional regulator
HLNCHOAK_01101 2.6e-244 msmE G Bacterial extracellular solute-binding protein
HLNCHOAK_01102 8.2e-168 amyD P ABC transporter
HLNCHOAK_01103 9.8e-144 amyC P ABC transporter (permease)
HLNCHOAK_01104 4.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HLNCHOAK_01105 2.1e-51 ytwF P Sulfurtransferase
HLNCHOAK_01106 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLNCHOAK_01107 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HLNCHOAK_01108 1.1e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HLNCHOAK_01109 6.6e-210 yttB EGP Major facilitator Superfamily
HLNCHOAK_01110 1.1e-42 yttA 2.7.13.3 S Pfam Transposase IS66
HLNCHOAK_01111 0.0 bceB V ABC transporter (permease)
HLNCHOAK_01112 1.1e-138 bceA V ABC transporter, ATP-binding protein
HLNCHOAK_01113 1.6e-185 T PhoQ Sensor
HLNCHOAK_01114 5.1e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_01115 4.4e-231 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HLNCHOAK_01116 7.7e-126 ytrE V ABC transporter, ATP-binding protein
HLNCHOAK_01117 2.2e-142
HLNCHOAK_01118 2.3e-147 P ABC-2 family transporter protein
HLNCHOAK_01119 4.2e-161 ytrB P abc transporter atp-binding protein
HLNCHOAK_01120 5.1e-66 ytrA K GntR family transcriptional regulator
HLNCHOAK_01122 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HLNCHOAK_01123 4e-189 yhcC S Fe-S oxidoreductase
HLNCHOAK_01124 1.1e-104 ytqB J Putative rRNA methylase
HLNCHOAK_01125 1.3e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HLNCHOAK_01126 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HLNCHOAK_01127 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HLNCHOAK_01128 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HLNCHOAK_01129 0.0 asnB 6.3.5.4 E Asparagine synthase
HLNCHOAK_01130 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLNCHOAK_01131 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HLNCHOAK_01132 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HLNCHOAK_01133 2.1e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HLNCHOAK_01134 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HLNCHOAK_01135 2.4e-144 ytlC P ABC transporter
HLNCHOAK_01136 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HLNCHOAK_01137 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HLNCHOAK_01138 7e-63 ytkC S Bacteriophage holin family
HLNCHOAK_01139 2.1e-76 dps P Belongs to the Dps family
HLNCHOAK_01141 3.4e-71 ytkA S YtkA-like
HLNCHOAK_01142 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLNCHOAK_01143 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HLNCHOAK_01144 3.6e-41 rpmE2 J Ribosomal protein L31
HLNCHOAK_01145 1.8e-248 cydA 1.10.3.14 C oxidase, subunit
HLNCHOAK_01146 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HLNCHOAK_01147 1.1e-24 S Domain of Unknown Function (DUF1540)
HLNCHOAK_01148 4.4e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HLNCHOAK_01149 7.4e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HLNCHOAK_01150 1.4e-136 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HLNCHOAK_01151 2.6e-169 troA P Belongs to the bacterial solute-binding protein 9 family
HLNCHOAK_01152 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HLNCHOAK_01153 8.8e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HLNCHOAK_01154 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HLNCHOAK_01155 1.9e-152 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HLNCHOAK_01156 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HLNCHOAK_01157 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
HLNCHOAK_01158 2.6e-132 dksA T COG1734 DnaK suppressor protein
HLNCHOAK_01159 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
HLNCHOAK_01160 3.7e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLNCHOAK_01161 1.7e-179 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HLNCHOAK_01162 5.2e-234 ytcC M Glycosyltransferase Family 4
HLNCHOAK_01164 5.1e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
HLNCHOAK_01165 1.8e-217 cotSA M Glycosyl transferases group 1
HLNCHOAK_01166 9.7e-205 cotI S Spore coat protein
HLNCHOAK_01167 2.2e-76 tspO T membrane
HLNCHOAK_01168 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HLNCHOAK_01169 7.1e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HLNCHOAK_01170 8.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HLNCHOAK_01171 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HLNCHOAK_01172 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HLNCHOAK_01179 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLNCHOAK_01180 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLNCHOAK_01181 1.8e-37 yaaB S Domain of unknown function (DUF370)
HLNCHOAK_01182 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLNCHOAK_01183 2.4e-33 yaaA S S4 domain
HLNCHOAK_01184 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLNCHOAK_01185 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLNCHOAK_01186 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLNCHOAK_01187 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLNCHOAK_01188 6.5e-108 jag S single-stranded nucleic acid binding R3H
HLNCHOAK_01189 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLNCHOAK_01190 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLNCHOAK_01191 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HLNCHOAK_01192 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HLNCHOAK_01193 3.1e-72 S Bacterial PH domain
HLNCHOAK_01194 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HLNCHOAK_01195 2.1e-149 spo0J K Belongs to the ParB family
HLNCHOAK_01196 2.8e-111 yyaC S Sporulation protein YyaC
HLNCHOAK_01197 2.3e-176 yyaD S Membrane
HLNCHOAK_01198 2.3e-33 yyzM S protein conserved in bacteria
HLNCHOAK_01199 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLNCHOAK_01200 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLNCHOAK_01201 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HLNCHOAK_01202 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLNCHOAK_01203 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLNCHOAK_01204 4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
HLNCHOAK_01205 4.7e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HLNCHOAK_01206 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLNCHOAK_01207 9.6e-95 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HLNCHOAK_01208 6.1e-244 EGP Major facilitator superfamily
HLNCHOAK_01209 3.6e-168 yyaK S CAAX protease self-immunity
HLNCHOAK_01210 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HLNCHOAK_01211 2.2e-137 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HLNCHOAK_01212 8.4e-38 ydeP K HxlR-like helix-turn-helix
HLNCHOAK_01213 5.2e-104 yyaP 1.5.1.3 H RibD C-terminal domain
HLNCHOAK_01214 3.5e-66 yyaQ S YjbR
HLNCHOAK_01215 8.4e-93 yyaR K Acetyltransferase (GNAT) domain
HLNCHOAK_01216 5e-97 yyaS S Membrane
HLNCHOAK_01217 2e-71 yjcF S Acetyltransferase (GNAT) domain
HLNCHOAK_01218 5.6e-77 yybA 2.3.1.57 K transcriptional
HLNCHOAK_01219 6.6e-127 S Metallo-beta-lactamase superfamily
HLNCHOAK_01220 1.3e-66 yybH S SnoaL-like domain
HLNCHOAK_01221 2.4e-123
HLNCHOAK_01222 8.2e-110 K TipAS antibiotic-recognition domain
HLNCHOAK_01223 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HLNCHOAK_01225 1.1e-69
HLNCHOAK_01226 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HLNCHOAK_01227 1.4e-68 ydeP3 K Transcriptional regulator
HLNCHOAK_01228 3.9e-84 cotF M Spore coat protein
HLNCHOAK_01230 2.9e-160 yybS S membrane
HLNCHOAK_01231 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HLNCHOAK_01232 2.2e-73 rplI J binds to the 23S rRNA
HLNCHOAK_01233 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLNCHOAK_01234 8.4e-221 yeaN P COG2807 Cyanate permease
HLNCHOAK_01235 1.9e-15 yycC K YycC-like protein
HLNCHOAK_01237 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HLNCHOAK_01238 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HLNCHOAK_01239 1e-77 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLNCHOAK_01240 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLNCHOAK_01244 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_01245 0.0 vicK 2.7.13.3 T Histidine kinase
HLNCHOAK_01246 5.2e-259 yycH S protein conserved in bacteria
HLNCHOAK_01247 7.3e-155 yycI S protein conserved in bacteria
HLNCHOAK_01248 5.7e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HLNCHOAK_01249 9.3e-220 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLNCHOAK_01250 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HLNCHOAK_01251 9.6e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HLNCHOAK_01252 1.4e-254 rocE E amino acid
HLNCHOAK_01253 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HLNCHOAK_01255 5.5e-187 S aspartate phosphatase
HLNCHOAK_01256 1.2e-82 yycN 2.3.1.128 K Acetyltransferase
HLNCHOAK_01257 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HLNCHOAK_01258 6.7e-215 yycP
HLNCHOAK_01259 2.1e-33 yycQ S Protein of unknown function (DUF2651)
HLNCHOAK_01261 5.6e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HLNCHOAK_01262 1.4e-64
HLNCHOAK_01263 1.1e-09 S YyzF-like protein
HLNCHOAK_01264 4.4e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLNCHOAK_01265 6.2e-61 2.7.11.1 KLT Protein tyrosine kinase
HLNCHOAK_01266 5.1e-21 KLT Protein tyrosine kinase
HLNCHOAK_01267 1e-120
HLNCHOAK_01268 1.9e-13 S Uncharacterised protein conserved in bacteria (DUF2326)
HLNCHOAK_01269 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HLNCHOAK_01270 2.3e-11
HLNCHOAK_01271 1.7e-184 S Radical SAM superfamily
HLNCHOAK_01272 4.2e-133 yydH O Peptidase M50
HLNCHOAK_01273 1.6e-109 prrC P ABC transporter
HLNCHOAK_01274 6.8e-117 S ABC-2 family transporter protein
HLNCHOAK_01275 7.6e-13
HLNCHOAK_01276 1.8e-122 yydK K Transcriptional regulator
HLNCHOAK_01277 7.2e-16 bglF G phosphotransferase system
HLNCHOAK_01278 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HLNCHOAK_01279 2.1e-188 wgaE S Polysaccharide pyruvyl transferase
HLNCHOAK_01280 3.8e-287 ahpF O Alkyl hydroperoxide reductase
HLNCHOAK_01281 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HLNCHOAK_01282 2.3e-270 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLNCHOAK_01283 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HLNCHOAK_01284 1e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HLNCHOAK_01285 7.3e-127 gntR K transcriptional
HLNCHOAK_01286 7.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HLNCHOAK_01287 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
HLNCHOAK_01288 2.6e-118 yxaC M effector of murein hydrolase
HLNCHOAK_01289 7.6e-49 S LrgA family
HLNCHOAK_01290 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HLNCHOAK_01291 1.6e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_01292 1.3e-99 yxaF K Transcriptional regulator
HLNCHOAK_01293 5.4e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
HLNCHOAK_01294 3.1e-223 P Protein of unknown function (DUF418)
HLNCHOAK_01295 1.4e-75 yxaI S membrane protein domain
HLNCHOAK_01296 1.9e-63 S Family of unknown function (DUF5391)
HLNCHOAK_01297 1.2e-92 S PQQ-like domain
HLNCHOAK_01298 2.2e-31 yxaI S membrane protein domain
HLNCHOAK_01299 1.7e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HLNCHOAK_01300 6.3e-210 yxbF K Bacterial regulatory proteins, tetR family
HLNCHOAK_01301 5.3e-150 IQ Enoyl-(Acyl carrier protein) reductase
HLNCHOAK_01303 0.0 htpG O Molecular chaperone. Has ATPase activity
HLNCHOAK_01304 3.1e-243 csbC EGP Major facilitator Superfamily
HLNCHOAK_01305 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HLNCHOAK_01307 2.4e-175 iolS C Aldo keto reductase
HLNCHOAK_01308 4.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HLNCHOAK_01309 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLNCHOAK_01310 2.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HLNCHOAK_01311 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HLNCHOAK_01312 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HLNCHOAK_01313 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HLNCHOAK_01314 1.9e-234 iolF EGP Major facilitator Superfamily
HLNCHOAK_01315 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HLNCHOAK_01316 2.5e-166 iolH G Xylose isomerase-like TIM barrel
HLNCHOAK_01317 1.1e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HLNCHOAK_01318 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HLNCHOAK_01319 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_01320 1e-179 T PhoQ Sensor
HLNCHOAK_01321 2.6e-138 yxdL V ABC transporter, ATP-binding protein
HLNCHOAK_01322 0.0 yxdM V ABC transporter (permease)
HLNCHOAK_01323 3.4e-58 yxeA S Protein of unknown function (DUF1093)
HLNCHOAK_01324 4.3e-175 fhuD P ABC transporter
HLNCHOAK_01325 1.4e-68
HLNCHOAK_01326 5.6e-16 yxeD
HLNCHOAK_01327 1.3e-20 yxeE
HLNCHOAK_01330 2.6e-149 yidA S hydrolases of the HAD superfamily
HLNCHOAK_01331 5.5e-186 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HLNCHOAK_01332 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLNCHOAK_01333 7.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLNCHOAK_01334 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HLNCHOAK_01335 1.2e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
HLNCHOAK_01336 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HLNCHOAK_01337 9.4e-214 yxeP 3.5.1.47 E hydrolase activity
HLNCHOAK_01338 8.1e-249 yxeQ S MmgE/PrpD family
HLNCHOAK_01339 3.2e-198 eutH E Ethanolamine utilisation protein, EutH
HLNCHOAK_01340 2e-152 yxxB S Domain of Unknown Function (DUF1206)
HLNCHOAK_01341 6e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HLNCHOAK_01342 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLNCHOAK_01343 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLNCHOAK_01344 1e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HLNCHOAK_01345 1e-251 lysP E amino acid
HLNCHOAK_01346 3.1e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HLNCHOAK_01347 1.5e-233 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HLNCHOAK_01348 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HLNCHOAK_01349 7.5e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
HLNCHOAK_01350 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HLNCHOAK_01351 2.8e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HLNCHOAK_01352 2.3e-20 S Domain of unknown function (DUF5082)
HLNCHOAK_01353 1.4e-38 yxiC S Family of unknown function (DUF5344)
HLNCHOAK_01354 4.8e-35 S nuclease activity
HLNCHOAK_01355 1.6e-11 S LXG domain of WXG superfamily
HLNCHOAK_01357 7.3e-19 S Protein conserved in bacteria
HLNCHOAK_01359 3.2e-87 S nuclease activity
HLNCHOAK_01360 5.5e-53
HLNCHOAK_01361 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HLNCHOAK_01362 4.6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HLNCHOAK_01363 1.1e-72 yxiE T Belongs to the universal stress protein A family
HLNCHOAK_01364 1e-163 yxxF EG EamA-like transporter family
HLNCHOAK_01365 2.1e-36
HLNCHOAK_01366 1.9e-68 yxiG
HLNCHOAK_01367 2.3e-140
HLNCHOAK_01368 7.9e-85 yxiI S Protein of unknown function (DUF2716)
HLNCHOAK_01369 7.7e-43 yxiJ S YxiJ-like protein
HLNCHOAK_01372 2.9e-61 S Protein of unknown function (DUF2812)
HLNCHOAK_01373 1.4e-53 padR K Transcriptional regulator PadR-like family
HLNCHOAK_01374 2e-211 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HLNCHOAK_01375 2.1e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HLNCHOAK_01376 4.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
HLNCHOAK_01377 2.6e-110
HLNCHOAK_01378 8.3e-151 licT K transcriptional antiterminator
HLNCHOAK_01379 1.6e-142 exoK GH16 M licheninase activity
HLNCHOAK_01380 6.6e-224 citH C Citrate transporter
HLNCHOAK_01381 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HLNCHOAK_01382 3e-47 yxiS
HLNCHOAK_01383 9.4e-105 T Domain of unknown function (DUF4163)
HLNCHOAK_01384 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLNCHOAK_01385 4.6e-157 rlmA 2.1.1.187 Q Methyltransferase domain
HLNCHOAK_01386 9.8e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HLNCHOAK_01387 6.9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HLNCHOAK_01388 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HLNCHOAK_01389 2.4e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HLNCHOAK_01390 3.7e-218 yxjG 2.1.1.14 E Methionine synthase
HLNCHOAK_01391 1.6e-218 yxjG 2.1.1.14 E Methionine synthase
HLNCHOAK_01392 4.2e-86 yxjI S LURP-one-related
HLNCHOAK_01395 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HLNCHOAK_01396 3.4e-115 K helix_turn_helix, Lux Regulon
HLNCHOAK_01397 4.7e-179 yxjM T Signal transduction histidine kinase
HLNCHOAK_01398 1.2e-77 S Protein of unknown function (DUF1453)
HLNCHOAK_01399 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HLNCHOAK_01400 1.3e-74 yxkC S Domain of unknown function (DUF4352)
HLNCHOAK_01401 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLNCHOAK_01402 1.4e-270 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLNCHOAK_01403 1.6e-163 lrp QT PucR C-terminal helix-turn-helix domain
HLNCHOAK_01404 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HLNCHOAK_01405 2.8e-154 yxkH G Polysaccharide deacetylase
HLNCHOAK_01407 2.4e-306 3.4.24.84 O Peptidase family M48
HLNCHOAK_01408 1.5e-229 cimH C COG3493 Na citrate symporter
HLNCHOAK_01409 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
HLNCHOAK_01410 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HLNCHOAK_01411 1e-309 cydD V ATP-binding
HLNCHOAK_01412 0.0 cydD V ATP-binding protein
HLNCHOAK_01413 1.8e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLNCHOAK_01414 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HLNCHOAK_01415 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HLNCHOAK_01416 5.6e-47 yxlC S Family of unknown function (DUF5345)
HLNCHOAK_01417 2.2e-28
HLNCHOAK_01418 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
HLNCHOAK_01419 1.5e-166 yxlF V ABC transporter, ATP-binding protein
HLNCHOAK_01420 6.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLNCHOAK_01421 4.9e-213 yxlH EGP Major facilitator Superfamily
HLNCHOAK_01422 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HLNCHOAK_01423 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HLNCHOAK_01424 1.1e-19 yxzF
HLNCHOAK_01425 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HLNCHOAK_01426 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HLNCHOAK_01427 1.4e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLNCHOAK_01428 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HLNCHOAK_01429 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HLNCHOAK_01430 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HLNCHOAK_01431 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_01432 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLNCHOAK_01433 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLNCHOAK_01434 1.2e-232 dltB M membrane protein involved in D-alanine export
HLNCHOAK_01435 9.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLNCHOAK_01436 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HLNCHOAK_01437 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HLNCHOAK_01438 2e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HLNCHOAK_01439 1.7e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLNCHOAK_01440 4.4e-86 ywaE K Transcriptional regulator
HLNCHOAK_01441 3.2e-127 ywaF S Integral membrane protein
HLNCHOAK_01442 7e-169 gspA M General stress
HLNCHOAK_01443 4e-153 sacY K transcriptional antiterminator
HLNCHOAK_01444 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HLNCHOAK_01445 7.5e-272 epr 3.4.21.62 O Belongs to the peptidase S8 family
HLNCHOAK_01446 1.2e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLNCHOAK_01447 3.5e-123 ywbB S Protein of unknown function (DUF2711)
HLNCHOAK_01448 4.4e-67 ywbC 4.4.1.5 E glyoxalase
HLNCHOAK_01449 2.9e-218 ywbD 2.1.1.191 J Methyltransferase
HLNCHOAK_01450 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HLNCHOAK_01451 4.3e-209 ywbF EGP Major facilitator Superfamily
HLNCHOAK_01452 2.3e-111 ywbG M effector of murein hydrolase
HLNCHOAK_01453 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HLNCHOAK_01454 4.3e-153 ywbI K Transcriptional regulator
HLNCHOAK_01455 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLNCHOAK_01456 9.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLNCHOAK_01457 7.8e-16 P COG0672 High-affinity Fe2 Pb2 permease
HLNCHOAK_01458 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
HLNCHOAK_01459 1.9e-99 ywbN P Dyp-type peroxidase family protein
HLNCHOAK_01460 1e-110 ywbN P Dyp-type peroxidase family protein
HLNCHOAK_01461 2.8e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HLNCHOAK_01462 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLNCHOAK_01463 8.3e-48 ywcB S Protein of unknown function, DUF485
HLNCHOAK_01465 1.1e-121 ywcC K transcriptional regulator
HLNCHOAK_01466 9.5e-60 gtcA S GtrA-like protein
HLNCHOAK_01467 6.9e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLNCHOAK_01468 8.9e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HLNCHOAK_01469 1e-35 ywzA S membrane
HLNCHOAK_01470 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HLNCHOAK_01471 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HLNCHOAK_01472 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HLNCHOAK_01473 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HLNCHOAK_01474 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HLNCHOAK_01475 2.9e-202 rodA D Belongs to the SEDS family
HLNCHOAK_01476 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HLNCHOAK_01477 3.6e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLNCHOAK_01478 0.0 vpr O Belongs to the peptidase S8 family
HLNCHOAK_01480 7e-150 sacT K transcriptional antiterminator
HLNCHOAK_01481 1e-139 focA P Formate/nitrite transporter
HLNCHOAK_01482 1.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HLNCHOAK_01483 7.5e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HLNCHOAK_01484 2e-28 ywdA
HLNCHOAK_01485 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HLNCHOAK_01486 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HLNCHOAK_01487 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLNCHOAK_01488 9.4e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HLNCHOAK_01489 5e-48 ywdI S Family of unknown function (DUF5327)
HLNCHOAK_01490 3.2e-237 ywdJ F Xanthine uracil
HLNCHOAK_01491 4.3e-59 ywdK S small membrane protein
HLNCHOAK_01492 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HLNCHOAK_01493 9.1e-144 spsA M Spore Coat
HLNCHOAK_01494 7.5e-266 spsB M Capsule polysaccharide biosynthesis protein
HLNCHOAK_01495 2.1e-224 spsC E Belongs to the DegT DnrJ EryC1 family
HLNCHOAK_01496 4e-164 spsD 2.3.1.210 K Spore Coat
HLNCHOAK_01497 2.7e-213 spsE 2.5.1.56 M acid synthase
HLNCHOAK_01498 3.5e-129 spsF M Spore Coat
HLNCHOAK_01499 3.6e-188 spsG M Spore Coat
HLNCHOAK_01500 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLNCHOAK_01501 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLNCHOAK_01502 4.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLNCHOAK_01503 6.7e-86 spsL 5.1.3.13 M Spore Coat
HLNCHOAK_01504 9.8e-77
HLNCHOAK_01505 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HLNCHOAK_01506 8.6e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HLNCHOAK_01507 0.0 rocB E arginine degradation protein
HLNCHOAK_01508 7.4e-250 lysP E amino acid
HLNCHOAK_01509 1.5e-204 ywfA EGP Major facilitator Superfamily
HLNCHOAK_01510 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HLNCHOAK_01511 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HLNCHOAK_01512 5.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_01513 4.7e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HLNCHOAK_01514 1.9e-209 bacE EGP Major facilitator Superfamily
HLNCHOAK_01515 1e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
HLNCHOAK_01516 1.6e-135 IQ Enoyl-(Acyl carrier protein) reductase
HLNCHOAK_01517 1.1e-146 ywfI C May function as heme-dependent peroxidase
HLNCHOAK_01518 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HLNCHOAK_01519 1.1e-156 cysL K Transcriptional regulator
HLNCHOAK_01520 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HLNCHOAK_01521 9.1e-156 ywfM EG EamA-like transporter family
HLNCHOAK_01522 5.1e-110 rsfA_1
HLNCHOAK_01523 3.1e-36 ywzC S Belongs to the UPF0741 family
HLNCHOAK_01524 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HLNCHOAK_01525 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HLNCHOAK_01526 6.2e-79 yffB K Transcriptional regulator
HLNCHOAK_01527 2e-237 mmr U Major Facilitator Superfamily
HLNCHOAK_01529 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLNCHOAK_01530 3.3e-71 ywhA K Transcriptional regulator
HLNCHOAK_01531 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HLNCHOAK_01532 5.1e-119 ywhC S Peptidase family M50
HLNCHOAK_01533 5.2e-95 ywhD S YwhD family
HLNCHOAK_01534 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HLNCHOAK_01535 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HLNCHOAK_01536 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HLNCHOAK_01537 1.1e-75 ywhH S Aminoacyl-tRNA editing domain
HLNCHOAK_01539 3.1e-79 S aspartate phosphatase
HLNCHOAK_01540 2.7e-191 ywhK CO amine dehydrogenase activity
HLNCHOAK_01541 8.1e-244 ywhL CO amine dehydrogenase activity
HLNCHOAK_01543 8.6e-248 L Peptidase, M16
HLNCHOAK_01544 5.5e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
HLNCHOAK_01545 1.5e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HLNCHOAK_01546 3.3e-132 cbiO V ABC transporter
HLNCHOAK_01548 4.9e-270 C Fe-S oxidoreductases
HLNCHOAK_01549 1e-07 S Bacteriocin subtilosin A
HLNCHOAK_01550 4.7e-73 ywiB S protein conserved in bacteria
HLNCHOAK_01551 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HLNCHOAK_01552 2.3e-213 narK P COG2223 Nitrate nitrite transporter
HLNCHOAK_01553 1e-128 fnr K helix_turn_helix, cAMP Regulatory protein
HLNCHOAK_01554 1.2e-137 ywiC S YwiC-like protein
HLNCHOAK_01555 7.7e-85 arfM T cyclic nucleotide binding
HLNCHOAK_01556 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLNCHOAK_01557 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
HLNCHOAK_01558 2.4e-93 narJ 1.7.5.1 C nitrate reductase
HLNCHOAK_01559 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
HLNCHOAK_01560 4.2e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLNCHOAK_01561 0.0 ywjA V ABC transporter
HLNCHOAK_01562 4.8e-96 ywjB H RibD C-terminal domain
HLNCHOAK_01563 2.7e-42 ywjC
HLNCHOAK_01564 3.6e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HLNCHOAK_01565 2.1e-219 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HLNCHOAK_01566 0.0 fadF C COG0247 Fe-S oxidoreductase
HLNCHOAK_01567 4.4e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HLNCHOAK_01568 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLNCHOAK_01569 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLNCHOAK_01570 3.9e-90 ywjG S Domain of unknown function (DUF2529)
HLNCHOAK_01571 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HLNCHOAK_01572 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HLNCHOAK_01573 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HLNCHOAK_01574 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLNCHOAK_01575 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HLNCHOAK_01576 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLNCHOAK_01577 1.1e-32 rpmE J Binds the 23S rRNA
HLNCHOAK_01578 1.6e-103 tdk 2.7.1.21 F thymidine kinase
HLNCHOAK_01579 0.0 sfcA 1.1.1.38 C malic enzyme
HLNCHOAK_01580 8.6e-160 ywkB S Membrane transport protein
HLNCHOAK_01581 6.4e-75 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HLNCHOAK_01582 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLNCHOAK_01583 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLNCHOAK_01584 2.6e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLNCHOAK_01586 3.7e-55 ywlA S Uncharacterised protein family (UPF0715)
HLNCHOAK_01587 3e-111 spoIIR S stage II sporulation protein R
HLNCHOAK_01588 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HLNCHOAK_01589 8.1e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLNCHOAK_01590 1.7e-91 mntP P Probably functions as a manganese efflux pump
HLNCHOAK_01591 3.6e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLNCHOAK_01592 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HLNCHOAK_01593 7.2e-95 ywlG S Belongs to the UPF0340 family
HLNCHOAK_01594 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLNCHOAK_01595 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLNCHOAK_01596 2.5e-62 atpI S ATP synthase
HLNCHOAK_01597 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HLNCHOAK_01598 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLNCHOAK_01599 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLNCHOAK_01600 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLNCHOAK_01601 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLNCHOAK_01602 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLNCHOAK_01603 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLNCHOAK_01604 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HLNCHOAK_01605 4.8e-87 ywmA
HLNCHOAK_01606 1.3e-32 ywzB S membrane
HLNCHOAK_01607 1.4e-133 ywmB S TATA-box binding
HLNCHOAK_01608 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLNCHOAK_01609 3.2e-176 spoIID D Stage II sporulation protein D
HLNCHOAK_01610 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HLNCHOAK_01611 8e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HLNCHOAK_01613 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HLNCHOAK_01614 1e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HLNCHOAK_01615 3.5e-104 S response regulator aspartate phosphatase
HLNCHOAK_01617 3.8e-84 ywmF S Peptidase M50
HLNCHOAK_01618 3.8e-11 csbD K CsbD-like
HLNCHOAK_01619 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HLNCHOAK_01620 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HLNCHOAK_01621 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HLNCHOAK_01622 1.7e-64 ywnA K Transcriptional regulator
HLNCHOAK_01623 3.1e-113 ywnB S NAD(P)H-binding
HLNCHOAK_01624 1.7e-58 ywnC S Family of unknown function (DUF5362)
HLNCHOAK_01625 2e-138 mta K transcriptional
HLNCHOAK_01626 8.7e-24 yqgA
HLNCHOAK_01627 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLNCHOAK_01628 2.2e-70 ywnF S Family of unknown function (DUF5392)
HLNCHOAK_01629 2.6e-09 ywnC S Family of unknown function (DUF5362)
HLNCHOAK_01630 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HLNCHOAK_01631 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HLNCHOAK_01632 3.5e-73 ywnJ S VanZ like family
HLNCHOAK_01633 5.9e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HLNCHOAK_01634 1.6e-58 nrgB K Belongs to the P(II) protein family
HLNCHOAK_01635 2.5e-225 amt P Ammonium transporter
HLNCHOAK_01636 2.6e-77
HLNCHOAK_01637 7.5e-103 phzA Q Isochorismatase family
HLNCHOAK_01638 9.1e-240 ywoD EGP Major facilitator superfamily
HLNCHOAK_01639 8.3e-279 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HLNCHOAK_01640 1.4e-230 ywoF P Right handed beta helix region
HLNCHOAK_01641 2.7e-211 ywoG EGP Major facilitator Superfamily
HLNCHOAK_01642 2.1e-70 ywoH K COG1846 Transcriptional regulators
HLNCHOAK_01643 3e-44 spoIIID K Stage III sporulation protein D
HLNCHOAK_01644 3.5e-180 mbl D Rod shape-determining protein
HLNCHOAK_01645 1.5e-125 flhO N flagellar basal body
HLNCHOAK_01646 2.6e-141 flhP N flagellar basal body
HLNCHOAK_01647 2e-197 S aspartate phosphatase
HLNCHOAK_01648 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLNCHOAK_01649 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLNCHOAK_01650 0.0 ywpD T PhoQ Sensor
HLNCHOAK_01651 3.1e-174 M1-574 T Transcriptional regulatory protein, C terminal
HLNCHOAK_01652 0.0 M1-568 M cell wall anchor domain
HLNCHOAK_01653 8.7e-84 srtA 3.4.22.70 M Sortase family
HLNCHOAK_01654 1.1e-66 ywpF S YwpF-like protein
HLNCHOAK_01655 1.3e-66 ywpG
HLNCHOAK_01656 3.7e-57 ssbB L Single-stranded DNA-binding protein
HLNCHOAK_01657 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HLNCHOAK_01658 2.8e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HLNCHOAK_01659 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HLNCHOAK_01660 1.6e-307 ywqB S SWIM zinc finger
HLNCHOAK_01661 1.2e-17
HLNCHOAK_01662 5.9e-116 ywqC M biosynthesis protein
HLNCHOAK_01663 4.9e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HLNCHOAK_01664 5.6e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HLNCHOAK_01665 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLNCHOAK_01666 1.3e-153 ywqG S Domain of unknown function (DUF1963)
HLNCHOAK_01667 9.7e-23 S Domain of unknown function (DUF5082)
HLNCHOAK_01668 1.3e-38 ywqI S Family of unknown function (DUF5344)
HLNCHOAK_01669 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
HLNCHOAK_01670 1.7e-52 S MORN repeat variant
HLNCHOAK_01671 2.2e-131 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HLNCHOAK_01672 2.9e-162 K Transcriptional regulator
HLNCHOAK_01673 1e-101 ywqN S NAD(P)H-dependent
HLNCHOAK_01675 1.3e-88 ywrA P COG2059 Chromate transport protein ChrA
HLNCHOAK_01676 1.2e-103 ywrB P Chromate transporter
HLNCHOAK_01677 8e-82 ywrC K Transcriptional regulator
HLNCHOAK_01678 1.5e-302 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HLNCHOAK_01679 1.2e-52 S Domain of unknown function (DUF4181)
HLNCHOAK_01680 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HLNCHOAK_01681 1.3e-12
HLNCHOAK_01682 6.2e-207 cotH M Spore Coat
HLNCHOAK_01683 1.4e-124 ywrJ
HLNCHOAK_01684 1.4e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HLNCHOAK_01685 1.1e-169 alsR K LysR substrate binding domain
HLNCHOAK_01686 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HLNCHOAK_01687 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HLNCHOAK_01688 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HLNCHOAK_01689 8e-48 ywsA S Protein of unknown function (DUF3892)
HLNCHOAK_01690 8.7e-93 batE T Sh3 type 3 domain protein
HLNCHOAK_01691 1.8e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HLNCHOAK_01692 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HLNCHOAK_01693 8.6e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HLNCHOAK_01694 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HLNCHOAK_01695 1.8e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLNCHOAK_01696 9.3e-178 rbsR K transcriptional
HLNCHOAK_01697 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HLNCHOAK_01698 8.6e-70 pgsC S biosynthesis protein
HLNCHOAK_01699 6.3e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HLNCHOAK_01700 3.6e-21 ywtC
HLNCHOAK_01701 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HLNCHOAK_01702 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HLNCHOAK_01703 2.1e-169 ywtF K Transcriptional regulator
HLNCHOAK_01704 3.7e-244 ywtG EGP Major facilitator Superfamily
HLNCHOAK_01705 1.2e-197 gerAC S Spore germination protein
HLNCHOAK_01706 5.6e-187 gerBB E Spore germination protein
HLNCHOAK_01707 1e-244 gerBA EG Spore germination protein
HLNCHOAK_01708 7.4e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HLNCHOAK_01709 3.4e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLNCHOAK_01710 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLNCHOAK_01711 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLNCHOAK_01712 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HLNCHOAK_01713 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HLNCHOAK_01714 1.3e-94 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLNCHOAK_01715 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HLNCHOAK_01716 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HLNCHOAK_01717 9.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLNCHOAK_01718 3.8e-88
HLNCHOAK_01719 2.7e-131 M Glycosyltransferase like family 2
HLNCHOAK_01720 1.3e-147 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLNCHOAK_01721 8.5e-132 tagG GM Transport permease protein
HLNCHOAK_01722 4.9e-269 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HLNCHOAK_01723 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HLNCHOAK_01724 8.3e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HLNCHOAK_01725 8.4e-101 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HLNCHOAK_01726 1.6e-88 M Glycosyltransferase like family 2
HLNCHOAK_01727 6.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLNCHOAK_01728 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HLNCHOAK_01729 1e-11
HLNCHOAK_01730 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HLNCHOAK_01731 3.5e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HLNCHOAK_01732 1.1e-94 M Glycosyltransferase like family 2
HLNCHOAK_01733 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HLNCHOAK_01734 3.1e-246 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLNCHOAK_01735 2.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HLNCHOAK_01736 9.9e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLNCHOAK_01737 1.8e-262 tuaE M Teichuronic acid biosynthesis protein
HLNCHOAK_01738 6.2e-103 tuaF M protein involved in exopolysaccharide biosynthesis
HLNCHOAK_01739 6.2e-145 tuaG GT2 M Glycosyltransferase like family 2
HLNCHOAK_01740 2.5e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HLNCHOAK_01741 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HLNCHOAK_01742 1.3e-162 yvhJ K Transcriptional regulator
HLNCHOAK_01743 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HLNCHOAK_01744 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HLNCHOAK_01745 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLNCHOAK_01746 2.1e-154 degV S protein conserved in bacteria
HLNCHOAK_01747 7.6e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HLNCHOAK_01748 3.7e-45 comFB S Late competence development protein ComFB
HLNCHOAK_01749 1.2e-80 comFC S Phosphoribosyl transferase domain
HLNCHOAK_01750 2e-73 yvyF S flagellar protein
HLNCHOAK_01751 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
HLNCHOAK_01752 2.7e-77 flgN NOU FlgN protein
HLNCHOAK_01753 1.2e-264 flgK N flagellar hook-associated protein
HLNCHOAK_01754 7.8e-155 flgL N Belongs to the bacterial flagellin family
HLNCHOAK_01755 5.7e-50 yviE
HLNCHOAK_01756 8e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HLNCHOAK_01757 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HLNCHOAK_01758 7.7e-80 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HLNCHOAK_01759 1.2e-55 flaG N flagellar protein FlaG
HLNCHOAK_01760 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HLNCHOAK_01761 2.9e-69 fliS N flagellar protein FliS
HLNCHOAK_01762 1.9e-08 fliT S bacterial-type flagellum organization
HLNCHOAK_01763 1.8e-65
HLNCHOAK_01764 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLNCHOAK_01765 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLNCHOAK_01766 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLNCHOAK_01767 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HLNCHOAK_01768 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HLNCHOAK_01769 2.7e-123 ftsE D cell division ATP-binding protein FtsE
HLNCHOAK_01770 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HLNCHOAK_01771 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HLNCHOAK_01772 5.3e-56 swrA S Swarming motility protein
HLNCHOAK_01773 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLNCHOAK_01774 7.4e-226 yvkA EGP Major facilitator Superfamily
HLNCHOAK_01775 1e-99 yvkB K Transcriptional regulator
HLNCHOAK_01776 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HLNCHOAK_01777 1.2e-30 csbA S protein conserved in bacteria
HLNCHOAK_01778 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLNCHOAK_01779 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLNCHOAK_01780 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HLNCHOAK_01781 7.4e-33 yvkN
HLNCHOAK_01782 1.8e-48 yvlA
HLNCHOAK_01783 2.4e-166 yvlB S Putative adhesin
HLNCHOAK_01784 2.6e-26 pspB KT PspC domain
HLNCHOAK_01785 1.2e-50 yvlD S Membrane
HLNCHOAK_01786 2.7e-203 yvmA EGP Major facilitator Superfamily
HLNCHOAK_01787 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
HLNCHOAK_01788 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HLNCHOAK_01789 1.2e-227 cypX 1.14.15.13 C Cytochrome P450
HLNCHOAK_01790 9.5e-72 adcR K helix_turn_helix multiple antibiotic resistance protein
HLNCHOAK_01791 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HLNCHOAK_01792 1.8e-133 yvoA K transcriptional
HLNCHOAK_01793 1.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLNCHOAK_01794 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLNCHOAK_01795 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLNCHOAK_01796 1.6e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLNCHOAK_01797 3.4e-161 yvoD P COG0370 Fe2 transport system protein B
HLNCHOAK_01798 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HLNCHOAK_01799 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HLNCHOAK_01800 1.3e-117 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HLNCHOAK_01801 5e-139 yvpB NU protein conserved in bacteria
HLNCHOAK_01802 5.3e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HLNCHOAK_01803 2.8e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HLNCHOAK_01804 1.1e-226 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HLNCHOAK_01805 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HLNCHOAK_01806 9.9e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLNCHOAK_01807 1.3e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HLNCHOAK_01808 4.1e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLNCHOAK_01809 9.8e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HLNCHOAK_01810 1.7e-121
HLNCHOAK_01811 3e-122
HLNCHOAK_01813 0.0 msbA2 3.6.3.44 V ABC transporter
HLNCHOAK_01814 2.9e-276 S COG0457 FOG TPR repeat
HLNCHOAK_01815 5.6e-99 usp CBM50 M protein conserved in bacteria
HLNCHOAK_01816 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLNCHOAK_01817 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HLNCHOAK_01818 1.7e-165 rapZ S Displays ATPase and GTPase activities
HLNCHOAK_01819 1.4e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HLNCHOAK_01820 1.4e-170 whiA K May be required for sporulation
HLNCHOAK_01821 8e-36 crh G Phosphocarrier protein Chr
HLNCHOAK_01822 9.8e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HLNCHOAK_01823 1.8e-33
HLNCHOAK_01824 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_01825 2.4e-195 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HLNCHOAK_01826 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HLNCHOAK_01827 0.0 yxdM V ABC transporter (permease)
HLNCHOAK_01828 4.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLNCHOAK_01829 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HLNCHOAK_01830 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HLNCHOAK_01831 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HLNCHOAK_01832 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HLNCHOAK_01833 1.1e-172 yvdE K Transcriptional regulator
HLNCHOAK_01834 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HLNCHOAK_01835 1.1e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HLNCHOAK_01836 1.1e-242 malC P COG1175 ABC-type sugar transport systems, permease components
HLNCHOAK_01837 6.6e-148 malD P transport
HLNCHOAK_01838 2e-158 malA S Protein of unknown function (DUF1189)
HLNCHOAK_01839 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HLNCHOAK_01840 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HLNCHOAK_01841 3.5e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HLNCHOAK_01842 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLNCHOAK_01844 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
HLNCHOAK_01845 5.4e-50 sugE P Small Multidrug Resistance protein
HLNCHOAK_01846 1.5e-50 ykkC P Small Multidrug Resistance protein
HLNCHOAK_01847 2.4e-104 yvdT K Transcriptional regulator
HLNCHOAK_01848 1.8e-295 yveA E amino acid
HLNCHOAK_01849 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HLNCHOAK_01850 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HLNCHOAK_01851 1e-262 pbpE V Beta-lactamase
HLNCHOAK_01852 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HLNCHOAK_01853 3.2e-72 MA20_18690 S Protein of unknown function (DUF3237)
HLNCHOAK_01854 5.1e-92 padC Q Phenolic acid decarboxylase
HLNCHOAK_01856 4.7e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HLNCHOAK_01857 6.3e-76 slr K transcriptional
HLNCHOAK_01858 4e-122 ywqC M biosynthesis protein
HLNCHOAK_01859 3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HLNCHOAK_01860 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HLNCHOAK_01861 8e-221 epsD GT4 M Glycosyl transferase 4-like
HLNCHOAK_01862 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HLNCHOAK_01863 4.1e-217 epsF GT4 M Glycosyl transferases group 1
HLNCHOAK_01864 1.1e-206 epsG S EpsG family
HLNCHOAK_01865 2.4e-192 epsH GT2 S Glycosyltransferase like family 2
HLNCHOAK_01866 9.2e-203 epsI GM pyruvyl transferase
HLNCHOAK_01867 3.1e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HLNCHOAK_01868 1.2e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLNCHOAK_01869 2e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HLNCHOAK_01870 3e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HLNCHOAK_01871 1.3e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HLNCHOAK_01872 1e-184 yvfF GM Exopolysaccharide biosynthesis protein
HLNCHOAK_01873 1e-31 yvfG S YvfG protein
HLNCHOAK_01874 2.7e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HLNCHOAK_01875 7.5e-308 yvfH C L-lactate permease
HLNCHOAK_01876 5e-112 yvfI K COG2186 Transcriptional regulators
HLNCHOAK_01877 2e-183 lacR K Transcriptional regulator
HLNCHOAK_01878 1e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
HLNCHOAK_01879 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HLNCHOAK_01880 7.2e-150 ganQ P transport
HLNCHOAK_01881 0.0 lacA 3.2.1.23 G beta-galactosidase
HLNCHOAK_01882 1.4e-250 galA 3.2.1.89 G arabinogalactan
HLNCHOAK_01883 5.3e-199 rsbU 3.1.3.3 T response regulator
HLNCHOAK_01884 7.5e-157 rsbQ S Alpha/beta hydrolase family
HLNCHOAK_01886 4.9e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HLNCHOAK_01887 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
HLNCHOAK_01888 2.1e-194 desK 2.7.13.3 T Histidine kinase
HLNCHOAK_01889 1.5e-53 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLNCHOAK_01890 5.8e-29 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLNCHOAK_01891 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HLNCHOAK_01892 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HLNCHOAK_01893 3.7e-131 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HLNCHOAK_01894 6.8e-195 yvbX S Glycosyl hydrolase
HLNCHOAK_01895 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HLNCHOAK_01896 2.1e-155 yvbV EG EamA-like transporter family
HLNCHOAK_01897 9.6e-158 yvbU K Transcriptional regulator
HLNCHOAK_01898 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLNCHOAK_01899 5.5e-203 araR K transcriptional
HLNCHOAK_01900 8.2e-252 araE EGP Major facilitator Superfamily
HLNCHOAK_01901 1.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HLNCHOAK_01902 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLNCHOAK_01903 1.1e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HLNCHOAK_01904 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLNCHOAK_01905 4.9e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HLNCHOAK_01906 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLNCHOAK_01907 2.4e-165 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HLNCHOAK_01908 1.3e-217 1.1.1.136 M UDP binding domain
HLNCHOAK_01909 3.3e-187 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HLNCHOAK_01910 2.1e-147 5.1.3.2 M GDP-mannose 4,6 dehydratase
HLNCHOAK_01911 2.3e-157 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HLNCHOAK_01912 1.5e-114 M Protein involved in cellulose biosynthesis
HLNCHOAK_01913 6.4e-123 C WbqC-like protein family
HLNCHOAK_01914 2.3e-114 S GlcNAc-PI de-N-acetylase
HLNCHOAK_01915 3.7e-152
HLNCHOAK_01916 1.6e-174 EGP Major facilitator Superfamily
HLNCHOAK_01917 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
HLNCHOAK_01918 0.0 tcaA S response to antibiotic
HLNCHOAK_01919 5.2e-122 exoY M Membrane
HLNCHOAK_01920 1.2e-106 yvbH S YvbH-like oligomerisation region
HLNCHOAK_01921 8.3e-103 yvbG U UPF0056 membrane protein
HLNCHOAK_01922 1.3e-96 yvbF K Belongs to the GbsR family
HLNCHOAK_01923 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HLNCHOAK_01924 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HLNCHOAK_01925 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLNCHOAK_01926 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HLNCHOAK_01927 3.3e-60 yvbF K Belongs to the GbsR family
HLNCHOAK_01928 2.6e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HLNCHOAK_01929 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HLNCHOAK_01930 2.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLNCHOAK_01931 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HLNCHOAK_01932 3.8e-219 NT chemotaxis protein
HLNCHOAK_01933 2.2e-54 yodB K transcriptional
HLNCHOAK_01934 1.2e-68 yvaO K Cro/C1-type HTH DNA-binding domain
HLNCHOAK_01935 8.8e-69 K transcriptional
HLNCHOAK_01936 9.8e-36 yvzC K Transcriptional
HLNCHOAK_01937 8.2e-153 yvaM S Serine aminopeptidase, S33
HLNCHOAK_01938 2.4e-23 secG U Preprotein translocase subunit SecG
HLNCHOAK_01939 3.7e-142 est 3.1.1.1 S Carboxylesterase
HLNCHOAK_01940 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLNCHOAK_01941 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HLNCHOAK_01943 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_01944 8.6e-99 K Bacterial regulatory proteins, tetR family
HLNCHOAK_01945 1.8e-54 yvaE P Small Multidrug Resistance protein
HLNCHOAK_01946 9.7e-73 yvaD S Family of unknown function (DUF5360)
HLNCHOAK_01947 0.0 yvaC S Fusaric acid resistance protein-like
HLNCHOAK_01948 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLNCHOAK_01949 2e-194 yvaA 1.1.1.371 S Oxidoreductase
HLNCHOAK_01950 2.2e-48 csoR S transcriptional
HLNCHOAK_01951 1.5e-29 copZ P Copper resistance protein CopZ
HLNCHOAK_01952 0.0 copA 3.6.3.54 P P-type ATPase
HLNCHOAK_01953 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HLNCHOAK_01954 1.6e-104 bdbD O Thioredoxin
HLNCHOAK_01955 6.5e-72 bdbC O Required for disulfide bond formation in some proteins
HLNCHOAK_01956 6e-106 yvgT S membrane
HLNCHOAK_01958 0.0 helD 3.6.4.12 L DNA helicase
HLNCHOAK_01959 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HLNCHOAK_01960 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HLNCHOAK_01961 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HLNCHOAK_01962 9.3e-86 yvgO
HLNCHOAK_01963 2.5e-155 yvgN S reductase
HLNCHOAK_01964 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
HLNCHOAK_01965 4.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HLNCHOAK_01966 7e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HLNCHOAK_01967 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HLNCHOAK_01968 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HLNCHOAK_01969 6.5e-16 S Small spore protein J (Spore_SspJ)
HLNCHOAK_01970 1.4e-235 yvsH E Arginine ornithine antiporter
HLNCHOAK_01971 5.3e-178 fhuD P ABC transporter
HLNCHOAK_01972 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_01973 1e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_01974 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HLNCHOAK_01975 4.8e-176 M Efflux transporter rnd family, mfp subunit
HLNCHOAK_01976 7.9e-123 macB V ABC transporter, ATP-binding protein
HLNCHOAK_01977 5.3e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HLNCHOAK_01978 1.3e-64 yvrL S Regulatory protein YrvL
HLNCHOAK_01979 8.2e-187 oxdC 4.1.1.2 G Oxalate decarboxylase
HLNCHOAK_01980 1.1e-23 oxdC 4.1.1.2 G Oxalate decarboxylase
HLNCHOAK_01981 2.4e-19 S YvrJ protein family
HLNCHOAK_01982 9.5e-98 yvrI K RNA polymerase
HLNCHOAK_01983 3.6e-22
HLNCHOAK_01984 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_01985 0.0 T PhoQ Sensor
HLNCHOAK_01986 9.9e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HLNCHOAK_01987 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_01988 2.2e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HLNCHOAK_01989 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_01990 6.2e-241 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HLNCHOAK_01991 1.4e-99 yvqK 2.5.1.17 S Adenosyltransferase
HLNCHOAK_01992 2.7e-225 yvqJ EGP Major facilitator Superfamily
HLNCHOAK_01993 2.8e-61 liaI S membrane
HLNCHOAK_01994 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HLNCHOAK_01995 1.2e-120 liaG S Putative adhesin
HLNCHOAK_01996 3e-125 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HLNCHOAK_01997 7.9e-186 vraS 2.7.13.3 T Histidine kinase
HLNCHOAK_01998 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLNCHOAK_01999 1.5e-184 gerAC S Spore germination B3/ GerAC like, C-terminal
HLNCHOAK_02000 3.8e-196 gerAB E Spore germination protein
HLNCHOAK_02001 1.2e-245 gerAA EG Spore germination protein
HLNCHOAK_02002 3.9e-24 S Protein of unknown function (DUF3970)
HLNCHOAK_02003 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLNCHOAK_02004 4.3e-158 yuxN K Transcriptional regulator
HLNCHOAK_02005 1.7e-249 cssS 2.7.13.3 T PhoQ Sensor
HLNCHOAK_02006 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_02007 5.8e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLNCHOAK_02008 8e-79 dps P Ferritin-like domain
HLNCHOAK_02009 4.9e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_02010 1.4e-299 pepF2 E COG1164 Oligoendopeptidase F
HLNCHOAK_02011 2.5e-66 S YusW-like protein
HLNCHOAK_02012 1e-153 yusV 3.6.3.34 HP ABC transporter
HLNCHOAK_02013 5.6e-39 yusU S Protein of unknown function (DUF2573)
HLNCHOAK_02014 5.7e-158 yusT K LysR substrate binding domain
HLNCHOAK_02015 5e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_02016 2.7e-64 yusQ S Tautomerase enzyme
HLNCHOAK_02017 3.6e-291 yusP P Major facilitator superfamily
HLNCHOAK_02018 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
HLNCHOAK_02019 5.4e-53 yusN M Coat F domain
HLNCHOAK_02020 5.1e-40
HLNCHOAK_02021 1.9e-164 fadM E Proline dehydrogenase
HLNCHOAK_02022 8.1e-09 S YuzL-like protein
HLNCHOAK_02023 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HLNCHOAK_02024 1.1e-214 fadA 2.3.1.16 I Belongs to the thiolase family
HLNCHOAK_02025 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HLNCHOAK_02026 5.3e-62 arsC 1.20.4.1 P Belongs to the ArsC family
HLNCHOAK_02027 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HLNCHOAK_02028 1.1e-39 yusG S Protein of unknown function (DUF2553)
HLNCHOAK_02029 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HLNCHOAK_02030 1.2e-54 traF CO Thioredoxin
HLNCHOAK_02031 2.1e-55 yusD S SCP-2 sterol transfer family
HLNCHOAK_02032 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLNCHOAK_02033 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HLNCHOAK_02034 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
HLNCHOAK_02035 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HLNCHOAK_02036 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HLNCHOAK_02037 4.5e-244 sufD O assembly protein SufD
HLNCHOAK_02038 1e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLNCHOAK_02039 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HLNCHOAK_02040 3.5e-271 sufB O FeS cluster assembly
HLNCHOAK_02041 1.6e-64 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLNCHOAK_02042 1.5e-37
HLNCHOAK_02044 1.3e-204 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HLNCHOAK_02045 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HLNCHOAK_02046 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HLNCHOAK_02047 8e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HLNCHOAK_02048 1.2e-155 yurN G Binding-protein-dependent transport system inner membrane component
HLNCHOAK_02049 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
HLNCHOAK_02050 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HLNCHOAK_02051 3.3e-135 yurK K UTRA
HLNCHOAK_02052 5.9e-205 msmX P Belongs to the ABC transporter superfamily
HLNCHOAK_02053 1.5e-166 bsn L Ribonuclease
HLNCHOAK_02054 1.7e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HLNCHOAK_02055 7.8e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HLNCHOAK_02056 4.4e-183 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HLNCHOAK_02057 1.3e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HLNCHOAK_02058 1.3e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HLNCHOAK_02059 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HLNCHOAK_02060 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HLNCHOAK_02062 1.7e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HLNCHOAK_02063 3.7e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HLNCHOAK_02064 1.8e-208 pbuX F xanthine
HLNCHOAK_02065 1.3e-230 pbuX F Permease family
HLNCHOAK_02066 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
HLNCHOAK_02067 1.9e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HLNCHOAK_02068 8.2e-60 yunG
HLNCHOAK_02069 7.3e-171 yunF S Protein of unknown function DUF72
HLNCHOAK_02070 2e-141 yunE S membrane transporter protein
HLNCHOAK_02071 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HLNCHOAK_02072 3.1e-47 yunC S Domain of unknown function (DUF1805)
HLNCHOAK_02073 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
HLNCHOAK_02074 1.3e-195 lytH M Peptidase, M23
HLNCHOAK_02075 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HLNCHOAK_02076 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLNCHOAK_02077 9.7e-48 yutD S protein conserved in bacteria
HLNCHOAK_02078 8.6e-75 yutE S Protein of unknown function DUF86
HLNCHOAK_02079 4.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLNCHOAK_02080 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HLNCHOAK_02081 6.5e-198 yutH S Spore coat protein
HLNCHOAK_02082 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
HLNCHOAK_02083 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HLNCHOAK_02084 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLNCHOAK_02085 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HLNCHOAK_02086 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HLNCHOAK_02087 1.1e-55 yuzD S protein conserved in bacteria
HLNCHOAK_02088 1.5e-197 yutJ 1.6.99.3 C NADH dehydrogenase
HLNCHOAK_02089 3.2e-39 yuzB S Belongs to the UPF0349 family
HLNCHOAK_02090 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLNCHOAK_02091 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLNCHOAK_02092 3.7e-63 erpA S Belongs to the HesB IscA family
HLNCHOAK_02093 2.3e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLNCHOAK_02094 6.5e-116 paiB K Putative FMN-binding domain
HLNCHOAK_02095 3.9e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLNCHOAK_02097 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HLNCHOAK_02098 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HLNCHOAK_02099 8.4e-27 yuiB S Putative membrane protein
HLNCHOAK_02100 1.4e-116 yuiC S protein conserved in bacteria
HLNCHOAK_02101 1.2e-77 yuiD S protein conserved in bacteria
HLNCHOAK_02102 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HLNCHOAK_02103 1.1e-210 yuiF S antiporter
HLNCHOAK_02104 1.3e-92 bioY S Biotin biosynthesis protein
HLNCHOAK_02105 1.9e-120 yuiH S Oxidoreductase molybdopterin binding domain
HLNCHOAK_02106 8.7e-167 besA S Putative esterase
HLNCHOAK_02107 2.1e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_02108 9.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
HLNCHOAK_02109 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HLNCHOAK_02110 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HLNCHOAK_02111 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLNCHOAK_02112 1.4e-35 mbtH S MbtH-like protein
HLNCHOAK_02113 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HLNCHOAK_02114 5.2e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HLNCHOAK_02115 4.7e-227 yukF QT Transcriptional regulator
HLNCHOAK_02116 2.8e-45 esxA S Belongs to the WXG100 family
HLNCHOAK_02117 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HLNCHOAK_02118 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HLNCHOAK_02119 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HLNCHOAK_02120 0.0 esaA S type VII secretion protein EsaA
HLNCHOAK_02121 3.3e-64 yueC S Family of unknown function (DUF5383)
HLNCHOAK_02122 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_02123 1.4e-95 yueE S phosphohydrolase
HLNCHOAK_02124 2.9e-24 S Protein of unknown function (DUF2642)
HLNCHOAK_02125 8.8e-71 S Protein of unknown function (DUF2283)
HLNCHOAK_02126 3.2e-190 yueF S transporter activity
HLNCHOAK_02127 1.7e-31 yueG S Spore germination protein gerPA/gerPF
HLNCHOAK_02128 7.4e-39 yueH S YueH-like protein
HLNCHOAK_02129 2.3e-66 yueI S Protein of unknown function (DUF1694)
HLNCHOAK_02130 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
HLNCHOAK_02131 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLNCHOAK_02132 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HLNCHOAK_02133 8.5e-23 yuzC
HLNCHOAK_02135 4.7e-142 comQ H Belongs to the FPP GGPP synthase family
HLNCHOAK_02137 1.4e-210 comP 2.7.13.3 T Histidine kinase
HLNCHOAK_02138 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLNCHOAK_02139 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HLNCHOAK_02140 1.7e-58 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HLNCHOAK_02141 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLNCHOAK_02142 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLNCHOAK_02143 5.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLNCHOAK_02144 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLNCHOAK_02145 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLNCHOAK_02146 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HLNCHOAK_02147 5e-15
HLNCHOAK_02148 8.2e-233 maeN C COG3493 Na citrate symporter
HLNCHOAK_02149 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HLNCHOAK_02150 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HLNCHOAK_02151 5.6e-270 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HLNCHOAK_02152 6.1e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HLNCHOAK_02153 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HLNCHOAK_02154 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HLNCHOAK_02155 6.3e-78 yufK S Family of unknown function (DUF5366)
HLNCHOAK_02156 4.1e-74 yuxK S protein conserved in bacteria
HLNCHOAK_02157 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HLNCHOAK_02158 4.2e-184 yuxJ EGP Major facilitator Superfamily
HLNCHOAK_02160 4.2e-115 kapD L the KinA pathway to sporulation
HLNCHOAK_02161 3.3e-70 kapB G Kinase associated protein B
HLNCHOAK_02162 6e-233 T PhoQ Sensor
HLNCHOAK_02163 2.1e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HLNCHOAK_02164 4.6e-39 yugE S Domain of unknown function (DUF1871)
HLNCHOAK_02165 1.4e-155 yugF I Hydrolase
HLNCHOAK_02166 1.6e-85 alaR K Transcriptional regulator
HLNCHOAK_02167 2.1e-199 yugH 2.6.1.1 E Aminotransferase
HLNCHOAK_02168 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HLNCHOAK_02169 4e-34 yuzA S Domain of unknown function (DUF378)
HLNCHOAK_02170 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HLNCHOAK_02171 1.2e-227 yugK C Dehydrogenase
HLNCHOAK_02172 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HLNCHOAK_02174 1.4e-71 yugN S YugN-like family
HLNCHOAK_02175 6.3e-182 yugO P COG1226 Kef-type K transport systems
HLNCHOAK_02176 5.4e-53 mstX S Membrane-integrating protein Mistic
HLNCHOAK_02177 3.9e-38
HLNCHOAK_02178 1.4e-116 yugP S Zn-dependent protease
HLNCHOAK_02179 1.3e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HLNCHOAK_02180 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HLNCHOAK_02181 2.1e-72 yugU S Uncharacterised protein family UPF0047
HLNCHOAK_02182 1e-35
HLNCHOAK_02183 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HLNCHOAK_02184 3.2e-225 mcpA NT chemotaxis protein
HLNCHOAK_02185 7.3e-222 mcpA NT chemotaxis protein
HLNCHOAK_02186 8.5e-295 mcpA NT chemotaxis protein
HLNCHOAK_02187 5.1e-239 mcpA NT chemotaxis protein
HLNCHOAK_02189 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HLNCHOAK_02190 1.1e-133 fucR K COG1349 Transcriptional regulators of sugar metabolism
HLNCHOAK_02191 2e-277 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HLNCHOAK_02192 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HLNCHOAK_02193 2e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HLNCHOAK_02194 7.4e-183 ygjR S Oxidoreductase
HLNCHOAK_02195 9.1e-196 yubA S transporter activity
HLNCHOAK_02196 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HLNCHOAK_02198 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HLNCHOAK_02199 8.3e-274 yubD P Major Facilitator Superfamily
HLNCHOAK_02200 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLNCHOAK_02201 1e-38 yiaA S yiaA/B two helix domain
HLNCHOAK_02202 1.6e-236 ktrB P Potassium
HLNCHOAK_02203 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HLNCHOAK_02204 6.3e-91 yuaB
HLNCHOAK_02205 3.6e-94 yuaC K Belongs to the GbsR family
HLNCHOAK_02206 1.5e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HLNCHOAK_02207 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
HLNCHOAK_02208 3.3e-106 yuaD
HLNCHOAK_02209 3.9e-84 yuaE S DinB superfamily
HLNCHOAK_02210 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HLNCHOAK_02211 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
HLNCHOAK_02212 6.4e-93 M1-753 M FR47-like protein
HLNCHOAK_02213 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HLNCHOAK_02214 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLNCHOAK_02215 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HLNCHOAK_02216 3.1e-63 yngL S Protein of unknown function (DUF1360)
HLNCHOAK_02217 7.2e-302 yngK T Glycosyl hydrolase-like 10
HLNCHOAK_02218 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HLNCHOAK_02219 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HLNCHOAK_02220 4.7e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HLNCHOAK_02221 1.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HLNCHOAK_02222 1.2e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HLNCHOAK_02223 5.4e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HLNCHOAK_02224 2e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HLNCHOAK_02225 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
HLNCHOAK_02226 5.5e-104 yngC S membrane-associated protein
HLNCHOAK_02227 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HLNCHOAK_02228 2e-79 yngA S membrane
HLNCHOAK_02230 4.4e-291 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HLNCHOAK_02231 9.1e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HLNCHOAK_02233 9.3e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HLNCHOAK_02234 1.8e-251 agcS E Sodium alanine symporter
HLNCHOAK_02235 8.6e-57 ynfC
HLNCHOAK_02236 2.3e-12
HLNCHOAK_02237 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLNCHOAK_02238 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLNCHOAK_02239 8.6e-69 yccU S CoA-binding protein
HLNCHOAK_02240 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLNCHOAK_02241 4.1e-49 yneR S Belongs to the HesB IscA family
HLNCHOAK_02242 1.3e-53 yneQ
HLNCHOAK_02243 1.2e-73 yneP S Thioesterase-like superfamily
HLNCHOAK_02244 3.9e-35 tlp S Belongs to the Tlp family
HLNCHOAK_02245 3.1e-08 sspN S Small acid-soluble spore protein N family
HLNCHOAK_02247 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLNCHOAK_02248 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HLNCHOAK_02249 2.5e-14 sspO S Belongs to the SspO family
HLNCHOAK_02250 3.9e-19 sspP S Belongs to the SspP family
HLNCHOAK_02251 2.2e-63 hspX O Spore coat protein
HLNCHOAK_02252 4.2e-74 yneK S Protein of unknown function (DUF2621)
HLNCHOAK_02253 1.9e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HLNCHOAK_02254 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HLNCHOAK_02255 1.2e-126 ccdA O cytochrome c biogenesis protein
HLNCHOAK_02256 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HLNCHOAK_02257 1.8e-28 yneF S UPF0154 protein
HLNCHOAK_02258 8.3e-81 yneE S Sporulation inhibitor of replication protein sirA
HLNCHOAK_02259 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLNCHOAK_02260 1.3e-32 ynzC S UPF0291 protein
HLNCHOAK_02261 9.2e-113 yneB L resolvase
HLNCHOAK_02262 1.3e-48 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HLNCHOAK_02263 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLNCHOAK_02264 4.9e-78 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HLNCHOAK_02265 5.8e-74 yndM S Protein of unknown function (DUF2512)
HLNCHOAK_02266 5.8e-135 yndL S Replication protein
HLNCHOAK_02268 1.6e-307 yndJ S YndJ-like protein
HLNCHOAK_02269 2.9e-116 yndH S Domain of unknown function (DUF4166)
HLNCHOAK_02270 1.4e-150 yndG S DoxX-like family
HLNCHOAK_02271 9.7e-217 gerLC S Spore germination protein
HLNCHOAK_02272 1.6e-194 gerAB U Spore germination
HLNCHOAK_02273 1.6e-285 gerAA EG Spore germination protein
HLNCHOAK_02276 2.6e-79 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HLNCHOAK_02277 1.2e-70
HLNCHOAK_02278 7.9e-25 tatA U protein secretion
HLNCHOAK_02281 3.2e-133 S Domain of unknown function, YrpD
HLNCHOAK_02283 2.5e-163 S Thymidylate synthase
HLNCHOAK_02286 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HLNCHOAK_02287 1.9e-80 yncE S Protein of unknown function (DUF2691)
HLNCHOAK_02288 5e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLNCHOAK_02289 3.6e-255 iolT EGP Major facilitator Superfamily
HLNCHOAK_02290 8.3e-111 yokF 3.1.31.1 L RNA catabolic process
HLNCHOAK_02291 1.4e-289 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HLNCHOAK_02292 4.4e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HLNCHOAK_02293 7.3e-214 xylR GK ROK family
HLNCHOAK_02294 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HLNCHOAK_02295 1e-254 xynT G MFS/sugar transport protein
HLNCHOAK_02296 5.3e-78 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HLNCHOAK_02298 2.2e-39 ynaF
HLNCHOAK_02299 1.7e-116 ynaE S Domain of unknown function (DUF3885)
HLNCHOAK_02300 3.4e-22 K Cro/C1-type HTH DNA-binding domain
HLNCHOAK_02301 4.7e-08 S Uncharacterised protein family (UPF0715)
HLNCHOAK_02302 4e-74 S CAAX protease self-immunity
HLNCHOAK_02303 3.6e-99 ynaD J Acetyltransferase (GNAT) domain
HLNCHOAK_02304 1.4e-216 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
HLNCHOAK_02305 1.1e-195 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HLNCHOAK_02306 1.9e-119 H Methionine biosynthesis protein MetW
HLNCHOAK_02307 4.9e-93 M Glycosyltransferase like family
HLNCHOAK_02309 7.3e-30
HLNCHOAK_02310 1.5e-09
HLNCHOAK_02311 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
HLNCHOAK_02312 1.1e-68 glnR K transcriptional
HLNCHOAK_02313 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HLNCHOAK_02314 4.7e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLNCHOAK_02315 1.7e-176 spoVK O stage V sporulation protein K
HLNCHOAK_02316 2.6e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HLNCHOAK_02317 4.9e-108 ymaB
HLNCHOAK_02318 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLNCHOAK_02319 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLNCHOAK_02320 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HLNCHOAK_02321 4.5e-22 ymzA
HLNCHOAK_02322 8.2e-23
HLNCHOAK_02323 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HLNCHOAK_02324 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLNCHOAK_02325 2.1e-46 ymaF S YmaF family
HLNCHOAK_02327 5.4e-50 ebrA P Small Multidrug Resistance protein
HLNCHOAK_02328 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HLNCHOAK_02329 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
HLNCHOAK_02330 2.1e-126 ymaC S Replication protein
HLNCHOAK_02331 1.9e-07 K Transcriptional regulator
HLNCHOAK_02332 8.6e-251 aprX O Belongs to the peptidase S8 family
HLNCHOAK_02333 8.9e-161 ymaE S Metallo-beta-lactamase superfamily
HLNCHOAK_02334 4.4e-61 ymzB
HLNCHOAK_02335 6.3e-232 cypA C Cytochrome P450
HLNCHOAK_02336 0.0 pks13 HQ Beta-ketoacyl synthase
HLNCHOAK_02337 0.0 dhbF IQ polyketide synthase
HLNCHOAK_02338 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HLNCHOAK_02339 0.0 pfaA Q Polyketide synthase of type I
HLNCHOAK_02340 0.0 rhiB IQ polyketide synthase
HLNCHOAK_02341 1e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HLNCHOAK_02342 4.2e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
HLNCHOAK_02343 1.5e-244 pksG 2.3.3.10 I synthase
HLNCHOAK_02344 4.3e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLNCHOAK_02345 1.4e-37 acpK IQ Phosphopantetheine attachment site
HLNCHOAK_02346 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HLNCHOAK_02347 1.2e-177 pksD Q Acyl transferase domain
HLNCHOAK_02349 1.2e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HLNCHOAK_02350 6.3e-125 pksB 3.1.2.6 S Polyketide biosynthesis
HLNCHOAK_02351 2.2e-108 pksA K Transcriptional regulator
HLNCHOAK_02352 3.9e-96 ymcC S Membrane
HLNCHOAK_02354 2e-69 S Regulatory protein YrvL
HLNCHOAK_02355 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLNCHOAK_02356 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLNCHOAK_02357 2.2e-88 cotE S Spore coat protein
HLNCHOAK_02358 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HLNCHOAK_02359 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HLNCHOAK_02360 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HLNCHOAK_02361 5.6e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HLNCHOAK_02362 1.2e-36 spoVS S Stage V sporulation protein S
HLNCHOAK_02363 1.9e-152 ymdB S protein conserved in bacteria
HLNCHOAK_02364 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HLNCHOAK_02365 1.1e-212 pbpX V Beta-lactamase
HLNCHOAK_02366 3.1e-187 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLNCHOAK_02367 4.3e-236 cinA 3.5.1.42 S Belongs to the CinA family
HLNCHOAK_02368 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLNCHOAK_02369 1.9e-124 ymfM S protein conserved in bacteria
HLNCHOAK_02370 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HLNCHOAK_02371 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HLNCHOAK_02372 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HLNCHOAK_02373 2.4e-242 ymfH S zinc protease
HLNCHOAK_02374 3e-232 ymfF S Peptidase M16
HLNCHOAK_02375 3.8e-205 ymfD EGP Major facilitator Superfamily
HLNCHOAK_02376 1.5e-132 ymfC K Transcriptional regulator
HLNCHOAK_02377 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HLNCHOAK_02378 4.4e-32 S YlzJ-like protein
HLNCHOAK_02379 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HLNCHOAK_02380 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLNCHOAK_02381 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLNCHOAK_02382 5e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HLNCHOAK_02383 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLNCHOAK_02384 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HLNCHOAK_02385 6.6e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HLNCHOAK_02386 2.6e-42 ymxH S YlmC YmxH family
HLNCHOAK_02387 4.4e-233 pepR S Belongs to the peptidase M16 family
HLNCHOAK_02388 3.6e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HLNCHOAK_02389 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HLNCHOAK_02390 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLNCHOAK_02391 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HLNCHOAK_02392 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLNCHOAK_02393 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLNCHOAK_02394 3.9e-44 ylxP S protein conserved in bacteria
HLNCHOAK_02395 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLNCHOAK_02396 3.1e-47 ylxQ J ribosomal protein
HLNCHOAK_02397 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HLNCHOAK_02398 1.1e-203 nusA K Participates in both transcription termination and antitermination
HLNCHOAK_02399 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HLNCHOAK_02400 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLNCHOAK_02401 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLNCHOAK_02402 7.7e-233 rasP M zinc metalloprotease
HLNCHOAK_02403 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HLNCHOAK_02404 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HLNCHOAK_02405 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLNCHOAK_02406 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLNCHOAK_02407 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HLNCHOAK_02408 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLNCHOAK_02409 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HLNCHOAK_02410 1.4e-76 ylxL
HLNCHOAK_02411 7.4e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLNCHOAK_02412 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HLNCHOAK_02413 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HLNCHOAK_02414 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HLNCHOAK_02415 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HLNCHOAK_02416 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HLNCHOAK_02417 1.4e-156 flhG D Belongs to the ParA family
HLNCHOAK_02418 6.8e-201 flhF N Flagellar biosynthesis regulator FlhF
HLNCHOAK_02419 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HLNCHOAK_02420 1.2e-189 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HLNCHOAK_02421 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HLNCHOAK_02422 2.2e-36 fliQ N Role in flagellar biosynthesis
HLNCHOAK_02423 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HLNCHOAK_02424 1.8e-95 fliZ N Flagellar biosynthesis protein, FliO
HLNCHOAK_02425 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HLNCHOAK_02426 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HLNCHOAK_02427 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HLNCHOAK_02428 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HLNCHOAK_02429 1.6e-135 flgG N Flagellar basal body rod
HLNCHOAK_02430 1.7e-72 flgD N Flagellar basal body rod modification protein
HLNCHOAK_02431 1.1e-214 fliK N Flagellar hook-length control protein
HLNCHOAK_02432 5.5e-35 ylxF S MgtE intracellular N domain
HLNCHOAK_02433 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HLNCHOAK_02434 3.6e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HLNCHOAK_02435 5.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HLNCHOAK_02436 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HLNCHOAK_02437 7e-255 fliF N The M ring may be actively involved in energy transduction
HLNCHOAK_02438 1.9e-31 fliE N Flagellar hook-basal body
HLNCHOAK_02439 1.7e-73 flgC N Belongs to the flagella basal body rod proteins family
HLNCHOAK_02440 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HLNCHOAK_02441 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HLNCHOAK_02442 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HLNCHOAK_02443 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HLNCHOAK_02444 2.5e-169 xerC L tyrosine recombinase XerC
HLNCHOAK_02445 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HLNCHOAK_02446 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLNCHOAK_02447 4.7e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HLNCHOAK_02448 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HLNCHOAK_02449 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HLNCHOAK_02450 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HLNCHOAK_02451 2.8e-286 ylqG
HLNCHOAK_02452 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLNCHOAK_02453 3.3e-155 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLNCHOAK_02454 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLNCHOAK_02455 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HLNCHOAK_02456 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLNCHOAK_02457 6.3e-61 ylqD S YlqD protein
HLNCHOAK_02458 4.5e-36 ylqC S Belongs to the UPF0109 family
HLNCHOAK_02459 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HLNCHOAK_02460 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLNCHOAK_02461 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLNCHOAK_02462 6.4e-87
HLNCHOAK_02463 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLNCHOAK_02464 0.0 smc D Required for chromosome condensation and partitioning
HLNCHOAK_02465 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLNCHOAK_02466 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLNCHOAK_02467 1.4e-128 IQ reductase
HLNCHOAK_02468 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HLNCHOAK_02469 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLNCHOAK_02470 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HLNCHOAK_02471 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLNCHOAK_02472 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
HLNCHOAK_02473 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HLNCHOAK_02474 4.6e-302 yloV S kinase related to dihydroxyacetone kinase
HLNCHOAK_02475 5.5e-59 asp S protein conserved in bacteria
HLNCHOAK_02476 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HLNCHOAK_02477 1.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
HLNCHOAK_02478 9.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HLNCHOAK_02479 7.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLNCHOAK_02480 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HLNCHOAK_02481 1.6e-140 stp 3.1.3.16 T phosphatase
HLNCHOAK_02482 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HLNCHOAK_02483 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLNCHOAK_02484 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLNCHOAK_02485 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLNCHOAK_02486 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLNCHOAK_02487 3.1e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLNCHOAK_02488 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLNCHOAK_02489 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HLNCHOAK_02490 1.5e-40 ylzA S Belongs to the UPF0296 family
HLNCHOAK_02491 2.4e-156 yloC S stress-induced protein
HLNCHOAK_02492 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HLNCHOAK_02493 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HLNCHOAK_02494 6.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HLNCHOAK_02495 8.4e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HLNCHOAK_02496 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HLNCHOAK_02497 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HLNCHOAK_02498 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HLNCHOAK_02499 1.8e-179 cysP P phosphate transporter
HLNCHOAK_02500 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HLNCHOAK_02502 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLNCHOAK_02503 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLNCHOAK_02504 1.9e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLNCHOAK_02505 1e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HLNCHOAK_02506 0.0 carB 6.3.5.5 F Belongs to the CarB family
HLNCHOAK_02507 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HLNCHOAK_02508 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLNCHOAK_02509 1.7e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HLNCHOAK_02510 2e-231 pyrP F Xanthine uracil
HLNCHOAK_02511 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLNCHOAK_02512 4.2e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLNCHOAK_02513 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLNCHOAK_02514 3.8e-63 dksA T COG1734 DnaK suppressor protein
HLNCHOAK_02515 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLNCHOAK_02516 2.6e-67 divIVA D Cell division initiation protein
HLNCHOAK_02517 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HLNCHOAK_02518 1.3e-39 yggT S membrane
HLNCHOAK_02519 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLNCHOAK_02520 4.6e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HLNCHOAK_02521 5.9e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HLNCHOAK_02522 2.4e-37 ylmC S sporulation protein
HLNCHOAK_02523 6.1e-254 argE 3.5.1.16 E Acetylornithine deacetylase
HLNCHOAK_02524 1.2e-146 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HLNCHOAK_02525 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLNCHOAK_02526 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLNCHOAK_02527 4.8e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HLNCHOAK_02528 0.0 bpr O COG1404 Subtilisin-like serine proteases
HLNCHOAK_02529 2.9e-202 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLNCHOAK_02530 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLNCHOAK_02531 6.2e-58 sbp S small basic protein
HLNCHOAK_02532 1.3e-102 ylxX S protein conserved in bacteria
HLNCHOAK_02533 5.6e-100 ylxW S protein conserved in bacteria
HLNCHOAK_02534 7.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLNCHOAK_02535 9e-167 murB 1.3.1.98 M cell wall formation
HLNCHOAK_02536 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLNCHOAK_02537 5.7e-186 spoVE D Belongs to the SEDS family
HLNCHOAK_02538 3.2e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLNCHOAK_02539 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLNCHOAK_02540 4.4e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLNCHOAK_02541 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HLNCHOAK_02542 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HLNCHOAK_02543 3.7e-44 ftsL D Essential cell division protein
HLNCHOAK_02544 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLNCHOAK_02545 2.9e-78 mraZ K Belongs to the MraZ family
HLNCHOAK_02546 3.5e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HLNCHOAK_02547 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLNCHOAK_02548 1.5e-88 ylbP K n-acetyltransferase
HLNCHOAK_02549 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HLNCHOAK_02550 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HLNCHOAK_02551 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HLNCHOAK_02553 3.8e-232 ylbM S Belongs to the UPF0348 family
HLNCHOAK_02554 6.8e-187 ylbL T Belongs to the peptidase S16 family
HLNCHOAK_02555 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HLNCHOAK_02556 1.6e-219 ylbJ S Sporulation integral membrane protein YlbJ
HLNCHOAK_02557 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLNCHOAK_02558 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
HLNCHOAK_02559 7.5e-39 ylbG S UPF0298 protein
HLNCHOAK_02560 1.8e-75 ylbF S Belongs to the UPF0342 family
HLNCHOAK_02561 6.7e-37 ylbE S YlbE-like protein
HLNCHOAK_02562 2.6e-62 ylbD S Putative coat protein
HLNCHOAK_02563 9.6e-200 ylbC S protein with SCP PR1 domains
HLNCHOAK_02564 2.6e-74 ylbB T COG0517 FOG CBS domain
HLNCHOAK_02565 7e-62 ylbA S YugN-like family
HLNCHOAK_02566 1.5e-166 ctaG S cytochrome c oxidase
HLNCHOAK_02567 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HLNCHOAK_02568 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HLNCHOAK_02569 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HLNCHOAK_02570 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HLNCHOAK_02571 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HLNCHOAK_02572 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HLNCHOAK_02573 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HLNCHOAK_02574 2.7e-211 ftsW D Belongs to the SEDS family
HLNCHOAK_02575 8.7e-44 ylaN S Belongs to the UPF0358 family
HLNCHOAK_02576 8e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HLNCHOAK_02577 1.3e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HLNCHOAK_02578 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HLNCHOAK_02579 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLNCHOAK_02580 2.5e-32 ylaI S protein conserved in bacteria
HLNCHOAK_02581 5.6e-47 ylaH S YlaH-like protein
HLNCHOAK_02582 0.0 typA T GTP-binding protein TypA
HLNCHOAK_02583 8.2e-22 S Family of unknown function (DUF5325)
HLNCHOAK_02584 2.6e-37 ylaE
HLNCHOAK_02585 1.2e-11 sigC S Putative zinc-finger
HLNCHOAK_02586 3.3e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HLNCHOAK_02587 2.7e-42 ylaB
HLNCHOAK_02588 0.0 ylaA
HLNCHOAK_02589 3.7e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HLNCHOAK_02590 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HLNCHOAK_02591 6.4e-76 ykzC S Acetyltransferase (GNAT) family
HLNCHOAK_02592 1.7e-148 suhB 3.1.3.25 G Inositol monophosphatase
HLNCHOAK_02593 7.1e-26 ykzI
HLNCHOAK_02594 4.6e-117 yktB S Belongs to the UPF0637 family
HLNCHOAK_02595 1.6e-42 yktA S Belongs to the UPF0223 family
HLNCHOAK_02596 1.3e-276 speA 4.1.1.19 E Arginine
HLNCHOAK_02597 2.7e-10 S SR1 protein
HLNCHOAK_02598 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HLNCHOAK_02599 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLNCHOAK_02600 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLNCHOAK_02601 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLNCHOAK_02602 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLNCHOAK_02603 1.1e-107 recN L Putative cell-wall binding lipoprotein
HLNCHOAK_02605 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLNCHOAK_02606 5.5e-147 ykrA S hydrolases of the HAD superfamily
HLNCHOAK_02607 8.2e-31 ykzG S Belongs to the UPF0356 family
HLNCHOAK_02608 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLNCHOAK_02609 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HLNCHOAK_02610 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HLNCHOAK_02611 6.1e-154 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HLNCHOAK_02612 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HLNCHOAK_02613 1.5e-43 abrB K of stationary sporulation gene expression
HLNCHOAK_02614 7.7e-183 mreB D Rod-share determining protein MreBH
HLNCHOAK_02615 2.5e-12 S Uncharacterized protein YkpC
HLNCHOAK_02616 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HLNCHOAK_02617 3.4e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLNCHOAK_02618 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLNCHOAK_02619 8.1e-39 ykoA
HLNCHOAK_02620 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HLNCHOAK_02621 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HLNCHOAK_02622 9e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HLNCHOAK_02623 3.1e-136 fruR K Transcriptional regulator
HLNCHOAK_02624 1.6e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HLNCHOAK_02625 2.5e-124 macB V ABC transporter, ATP-binding protein
HLNCHOAK_02626 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLNCHOAK_02627 2.3e-114 yknW S Yip1 domain
HLNCHOAK_02628 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HLNCHOAK_02629 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HLNCHOAK_02630 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HLNCHOAK_02631 7.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HLNCHOAK_02632 1.4e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HLNCHOAK_02633 5.8e-244 moeA 2.10.1.1 H molybdopterin
HLNCHOAK_02634 2e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HLNCHOAK_02635 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HLNCHOAK_02636 2.1e-145 yknT
HLNCHOAK_02637 1.5e-93 rok K Repressor of ComK
HLNCHOAK_02638 4.1e-80 ykuV CO thiol-disulfide
HLNCHOAK_02639 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HLNCHOAK_02640 8.8e-142 ykuT M Mechanosensitive ion channel
HLNCHOAK_02641 9e-37 ykuS S Belongs to the UPF0180 family
HLNCHOAK_02642 7.1e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLNCHOAK_02643 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLNCHOAK_02644 6.7e-78 fld C Flavodoxin
HLNCHOAK_02645 9.7e-174 ykuO
HLNCHOAK_02646 2.9e-84 fld C Flavodoxin domain
HLNCHOAK_02647 3.5e-168 ccpC K Transcriptional regulator
HLNCHOAK_02648 1.6e-76 ykuL S CBS domain
HLNCHOAK_02649 3.9e-27 ykzF S Antirepressor AbbA
HLNCHOAK_02650 4.4e-94 ykuK S Ribonuclease H-like
HLNCHOAK_02651 3.9e-37 ykuJ S protein conserved in bacteria
HLNCHOAK_02652 4.4e-233 ykuI T Diguanylate phosphodiesterase
HLNCHOAK_02653 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_02654 1.4e-164 ykuE S Metallophosphoesterase
HLNCHOAK_02655 1.8e-87 ykuD S protein conserved in bacteria
HLNCHOAK_02656 2.8e-238 ykuC EGP Major facilitator Superfamily
HLNCHOAK_02657 1.7e-84 ykyB S YkyB-like protein
HLNCHOAK_02658 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HLNCHOAK_02659 1.3e-15
HLNCHOAK_02660 4.4e-222 patA 2.6.1.1 E Aminotransferase
HLNCHOAK_02661 0.0 pilS 2.7.13.3 T Histidine kinase
HLNCHOAK_02662 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HLNCHOAK_02663 7e-120 ykwD J protein with SCP PR1 domains
HLNCHOAK_02664 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HLNCHOAK_02665 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HLNCHOAK_02666 2.2e-258 mcpC NT chemotaxis protein
HLNCHOAK_02667 5.9e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLNCHOAK_02668 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
HLNCHOAK_02669 2.1e-38 splA S Transcriptional regulator
HLNCHOAK_02670 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLNCHOAK_02671 2.1e-39 ptsH G phosphocarrier protein HPr
HLNCHOAK_02672 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HLNCHOAK_02673 7.6e-128 glcT K antiterminator
HLNCHOAK_02675 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
HLNCHOAK_02677 9.7e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HLNCHOAK_02678 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HLNCHOAK_02679 6.5e-90 stoA CO thiol-disulfide
HLNCHOAK_02680 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLNCHOAK_02681 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
HLNCHOAK_02682 2.8e-28
HLNCHOAK_02683 6e-25 ykvS S protein conserved in bacteria
HLNCHOAK_02684 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HLNCHOAK_02685 4.8e-163 G Glycosyl hydrolases family 18
HLNCHOAK_02686 3.5e-35 3.5.1.104 M LysM domain
HLNCHOAK_02687 2.1e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
HLNCHOAK_02688 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
HLNCHOAK_02689 2e-61 ykvN K Transcriptional regulator
HLNCHOAK_02690 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HLNCHOAK_02691 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HLNCHOAK_02692 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HLNCHOAK_02693 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HLNCHOAK_02694 1.4e-179 ykvI S membrane
HLNCHOAK_02695 0.0 clpE O Belongs to the ClpA ClpB family
HLNCHOAK_02696 2.7e-138 motA N flagellar motor
HLNCHOAK_02697 2.5e-125 motB N Flagellar motor protein
HLNCHOAK_02698 1.3e-75 ykvE K transcriptional
HLNCHOAK_02699 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HLNCHOAK_02700 1.4e-64 eag
HLNCHOAK_02701 6.4e-09 S Spo0E like sporulation regulatory protein
HLNCHOAK_02702 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HLNCHOAK_02703 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HLNCHOAK_02704 2.3e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HLNCHOAK_02705 5.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HLNCHOAK_02706 1.3e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HLNCHOAK_02707 2.3e-231 mtnE 2.6.1.83 E Aminotransferase
HLNCHOAK_02708 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HLNCHOAK_02709 1.8e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HLNCHOAK_02710 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HLNCHOAK_02712 5.9e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLNCHOAK_02713 0.0 kinE 2.7.13.3 T Histidine kinase
HLNCHOAK_02714 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HLNCHOAK_02715 4.1e-18 ykzE
HLNCHOAK_02716 1.2e-10 ydfR S Protein of unknown function (DUF421)
HLNCHOAK_02717 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HLNCHOAK_02718 3.5e-155 htpX O Belongs to the peptidase M48B family
HLNCHOAK_02719 3.3e-124 ykrK S Domain of unknown function (DUF1836)
HLNCHOAK_02720 1.9e-26 sspD S small acid-soluble spore protein
HLNCHOAK_02721 1.7e-106 rsgI S Anti-sigma factor N-terminus
HLNCHOAK_02722 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLNCHOAK_02723 3.7e-140 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HLNCHOAK_02724 2.7e-109 ykoX S membrane-associated protein
HLNCHOAK_02725 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HLNCHOAK_02726 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HLNCHOAK_02727 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HLNCHOAK_02728 1.4e-184 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HLNCHOAK_02729 0.0 ykoS
HLNCHOAK_02730 6.6e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HLNCHOAK_02731 2.7e-97 ykoP G polysaccharide deacetylase
HLNCHOAK_02732 8.9e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HLNCHOAK_02733 1.3e-81 mhqR K transcriptional
HLNCHOAK_02734 6.9e-26 ykoL
HLNCHOAK_02735 2.9e-17
HLNCHOAK_02736 1.4e-53 tnrA K transcriptional
HLNCHOAK_02737 2.2e-222 mgtE P Acts as a magnesium transporter
HLNCHOAK_02740 1.1e-84 ykoJ S Peptidase propeptide and YPEB domain
HLNCHOAK_02741 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
HLNCHOAK_02742 6.8e-243 ykoH 2.7.13.3 T Histidine kinase
HLNCHOAK_02743 1e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_02744 3.9e-110 ykoF S YKOF-related Family
HLNCHOAK_02745 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HLNCHOAK_02746 2.3e-309 P ABC transporter, ATP-binding protein
HLNCHOAK_02747 1.8e-136 ykoC P Cobalt transport protein
HLNCHOAK_02748 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLNCHOAK_02749 1.7e-176 isp O Belongs to the peptidase S8 family
HLNCHOAK_02750 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HLNCHOAK_02751 1.4e-86 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HLNCHOAK_02752 1.9e-71 ohrB O Organic hydroperoxide resistance protein
HLNCHOAK_02753 4.4e-74 ohrR K COG1846 Transcriptional regulators
HLNCHOAK_02754 8.2e-70 ohrA O Organic hydroperoxide resistance protein
HLNCHOAK_02755 1.2e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLNCHOAK_02756 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLNCHOAK_02757 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HLNCHOAK_02758 7e-50 ykkD P Multidrug resistance protein
HLNCHOAK_02759 3.5e-55 ykkC P Multidrug resistance protein
HLNCHOAK_02760 1.1e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLNCHOAK_02761 2e-97 ykkA S Protein of unknown function (DUF664)
HLNCHOAK_02762 2.7e-129 ykjA S Protein of unknown function (DUF421)
HLNCHOAK_02763 1e-10
HLNCHOAK_02764 1.6e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HLNCHOAK_02765 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HLNCHOAK_02766 5.9e-160 ykgA E Amidinotransferase
HLNCHOAK_02767 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
HLNCHOAK_02768 1.6e-185 ykfD E Belongs to the ABC transporter superfamily
HLNCHOAK_02769 2.7e-160 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HLNCHOAK_02770 8.3e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HLNCHOAK_02771 6e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HLNCHOAK_02773 0.0 dppE E ABC transporter substrate-binding protein
HLNCHOAK_02774 7.3e-186 dppD P Belongs to the ABC transporter superfamily
HLNCHOAK_02775 4.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLNCHOAK_02776 6.9e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLNCHOAK_02777 5.1e-153 dppA E D-aminopeptidase
HLNCHOAK_02778 6.7e-129 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HLNCHOAK_02779 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLNCHOAK_02781 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HLNCHOAK_02782 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLNCHOAK_02783 2.3e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HLNCHOAK_02784 1.3e-238 steT E amino acid
HLNCHOAK_02785 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HLNCHOAK_02786 7.6e-175 pit P phosphate transporter
HLNCHOAK_02787 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HLNCHOAK_02788 6.7e-23 spoIISB S Stage II sporulation protein SB
HLNCHOAK_02790 4.2e-161 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HLNCHOAK_02791 9.3e-40 xhlB S SPP1 phage holin
HLNCHOAK_02792 1.1e-38 xhlA S Haemolysin XhlA
HLNCHOAK_02793 1.7e-151 xepA
HLNCHOAK_02794 5.5e-22 xkdX
HLNCHOAK_02795 1.3e-43 S XkdW protein
HLNCHOAK_02796 0.0
HLNCHOAK_02797 1.9e-40
HLNCHOAK_02798 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HLNCHOAK_02799 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HLNCHOAK_02800 3.1e-69 xkdS S Protein of unknown function (DUF2634)
HLNCHOAK_02801 3e-38 xkdR S Protein of unknown function (DUF2577)
HLNCHOAK_02802 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HLNCHOAK_02803 2.7e-120 xkdP S Lysin motif
HLNCHOAK_02804 0.0 xkdO L Transglycosylase SLT domain
HLNCHOAK_02805 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HLNCHOAK_02806 6.1e-76 xkdM S Phage tail tube protein
HLNCHOAK_02807 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HLNCHOAK_02808 1.9e-77 xkdJ
HLNCHOAK_02809 9.9e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HLNCHOAK_02810 3.3e-64 yqbH S Domain of unknown function (DUF3599)
HLNCHOAK_02811 5.1e-63 yqbG S Protein of unknown function (DUF3199)
HLNCHOAK_02812 5.8e-169 xkdG S Phage capsid family
HLNCHOAK_02813 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HLNCHOAK_02814 3.5e-285 yqbA S portal protein
HLNCHOAK_02815 1.4e-253 xtmB S phage terminase, large subunit
HLNCHOAK_02816 4.5e-138 xtmA L phage terminase small subunit
HLNCHOAK_02817 7e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HLNCHOAK_02818 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HLNCHOAK_02821 6.4e-119 xkdC L Bacterial dnaA protein
HLNCHOAK_02822 1.9e-155 xkdB K sequence-specific DNA binding
HLNCHOAK_02824 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HLNCHOAK_02825 1.6e-111 xkdA E IrrE N-terminal-like domain
HLNCHOAK_02826 4.4e-160 ydbD P Catalase
HLNCHOAK_02827 2.4e-107 yjqB S Pfam:DUF867
HLNCHOAK_02828 6.8e-60 yjqA S Bacterial PH domain
HLNCHOAK_02829 1.6e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HLNCHOAK_02830 6.3e-41 S YCII-related domain
HLNCHOAK_02832 3e-212 S response regulator aspartate phosphatase
HLNCHOAK_02833 2.1e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HLNCHOAK_02834 8e-79 yjoA S DinB family
HLNCHOAK_02835 7.4e-130 MA20_18170 S membrane transporter protein
HLNCHOAK_02836 8.1e-282 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HLNCHOAK_02837 3.5e-282 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HLNCHOAK_02838 5.2e-184 exuR K transcriptional
HLNCHOAK_02839 1.4e-226 exuT G Sugar (and other) transporter
HLNCHOAK_02840 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HLNCHOAK_02841 2e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HLNCHOAK_02842 3.4e-191 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HLNCHOAK_02843 3.5e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HLNCHOAK_02844 7.8e-247 yjmB G symporter YjmB
HLNCHOAK_02845 7.9e-279 uxaC 5.3.1.12 G glucuronate isomerase
HLNCHOAK_02846 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HLNCHOAK_02847 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HLNCHOAK_02848 2.2e-90 yjlB S Cupin domain
HLNCHOAK_02849 2.3e-176 yjlA EG Putative multidrug resistance efflux transporter
HLNCHOAK_02850 6.8e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HLNCHOAK_02851 4.3e-122 ybbM S transport system, permease component
HLNCHOAK_02852 1.2e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HLNCHOAK_02853 8.2e-30
HLNCHOAK_02854 3.4e-99 dam2 2.1.1.72 L DNA methyltransferase
HLNCHOAK_02855 2.7e-216 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HLNCHOAK_02856 6.1e-224 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HLNCHOAK_02858 6.6e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HLNCHOAK_02860 4.3e-95 yjgD S Protein of unknown function (DUF1641)
HLNCHOAK_02861 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HLNCHOAK_02862 2e-103 yjgB S Domain of unknown function (DUF4309)
HLNCHOAK_02863 6e-45 T PhoQ Sensor
HLNCHOAK_02864 3.6e-105 yjfC O Predicted Zn-dependent protease (DUF2268)
HLNCHOAK_02865 7.7e-53 yjfC O Predicted Zn-dependent protease (DUF2268)
HLNCHOAK_02866 2.3e-20 yjfB S Putative motility protein
HLNCHOAK_02867 5.5e-83 S Protein of unknown function (DUF2690)
HLNCHOAK_02868 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
HLNCHOAK_02870 3.1e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HLNCHOAK_02871 3.5e-52 yjdJ S Domain of unknown function (DUF4306)
HLNCHOAK_02872 4.6e-28 S Domain of unknown function (DUF4177)
HLNCHOAK_02873 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLNCHOAK_02875 3.4e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HLNCHOAK_02876 6.5e-48 yjdF S Protein of unknown function (DUF2992)
HLNCHOAK_02877 2.4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
HLNCHOAK_02878 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HLNCHOAK_02879 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HLNCHOAK_02880 2.3e-45 yjcN
HLNCHOAK_02881 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
HLNCHOAK_02882 3.4e-128 S response regulator aspartate phosphatase
HLNCHOAK_02885 4.9e-21
HLNCHOAK_02886 1.5e-237 M nucleic acid phosphodiester bond hydrolysis
HLNCHOAK_02887 1e-29
HLNCHOAK_02888 1.6e-38
HLNCHOAK_02891 1.1e-212 yjcL S Protein of unknown function (DUF819)
HLNCHOAK_02892 3.5e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
HLNCHOAK_02893 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HLNCHOAK_02894 6.5e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HLNCHOAK_02895 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
HLNCHOAK_02896 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HLNCHOAK_02897 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLNCHOAK_02898 1.7e-38
HLNCHOAK_02899 0.0 yjcD 3.6.4.12 L DNA helicase
HLNCHOAK_02900 2.9e-38 spoVIF S Stage VI sporulation protein F
HLNCHOAK_02903 1.9e-56 yjcA S Protein of unknown function (DUF1360)
HLNCHOAK_02904 1.4e-23 cotV S Spore Coat Protein X and V domain
HLNCHOAK_02905 1.4e-10 cotW
HLNCHOAK_02906 1.4e-38 cotX S Spore Coat Protein X and V domain
HLNCHOAK_02907 3.4e-96 cotY S Spore coat protein Z
HLNCHOAK_02908 5.2e-83 cotZ S Spore coat protein
HLNCHOAK_02909 2.9e-53 yjbX S Spore coat protein
HLNCHOAK_02910 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HLNCHOAK_02911 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HLNCHOAK_02912 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HLNCHOAK_02913 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HLNCHOAK_02914 6.7e-30 thiS H thiamine diphosphate biosynthetic process
HLNCHOAK_02915 1.4e-217 thiO 1.4.3.19 E Glycine oxidase
HLNCHOAK_02916 1e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HLNCHOAK_02917 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HLNCHOAK_02918 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLNCHOAK_02919 8.7e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HLNCHOAK_02920 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLNCHOAK_02921 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLNCHOAK_02922 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HLNCHOAK_02923 2.1e-61 yjbL S Belongs to the UPF0738 family
HLNCHOAK_02924 4.1e-101 yjbK S protein conserved in bacteria
HLNCHOAK_02925 1e-99 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HLNCHOAK_02926 3.7e-72 yjbI S Bacterial-like globin
HLNCHOAK_02927 9.8e-163 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HLNCHOAK_02928 1.8e-20
HLNCHOAK_02929 0.0 pepF E oligoendopeptidase F
HLNCHOAK_02930 1.2e-219 yjbF S Competence protein
HLNCHOAK_02931 8.9e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HLNCHOAK_02932 6e-112 yjbE P Integral membrane protein TerC family
HLNCHOAK_02933 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLNCHOAK_02934 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLNCHOAK_02935 5.3e-210 yjbB EGP Major Facilitator Superfamily
HLNCHOAK_02936 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HLNCHOAK_02937 6.8e-198 oppD P Belongs to the ABC transporter superfamily
HLNCHOAK_02938 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLNCHOAK_02939 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLNCHOAK_02940 9.4e-308 oppA E ABC transporter substrate-binding protein
HLNCHOAK_02941 3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HLNCHOAK_02942 5e-147 yjbA S Belongs to the UPF0736 family
HLNCHOAK_02943 1.4e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLNCHOAK_02944 2.2e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLNCHOAK_02945 1.9e-276 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HLNCHOAK_02946 4.2e-186 appF E Belongs to the ABC transporter superfamily
HLNCHOAK_02947 1.8e-184 appD P Belongs to the ABC transporter superfamily
HLNCHOAK_02948 1.2e-148 yjaZ O Zn-dependent protease
HLNCHOAK_02949 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLNCHOAK_02950 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLNCHOAK_02951 5e-21 yjzB
HLNCHOAK_02952 7.3e-26 comZ S ComZ
HLNCHOAK_02953 2.5e-183 med S Transcriptional activator protein med
HLNCHOAK_02954 5.3e-101 yjaV
HLNCHOAK_02955 6.2e-142 yjaU I carboxylic ester hydrolase activity
HLNCHOAK_02956 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HLNCHOAK_02957 9.5e-28 yjzC S YjzC-like protein
HLNCHOAK_02958 4.2e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLNCHOAK_02959 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HLNCHOAK_02960 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HLNCHOAK_02961 5.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HLNCHOAK_02962 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HLNCHOAK_02963 1e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HLNCHOAK_02964 2.1e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HLNCHOAK_02965 1.7e-88 norB G Major Facilitator Superfamily
HLNCHOAK_02966 1.9e-267 yitY C D-arabinono-1,4-lactone oxidase
HLNCHOAK_02967 1.5e-22 pilT S Proteolipid membrane potential modulator
HLNCHOAK_02968 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HLNCHOAK_02969 7.6e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HLNCHOAK_02970 2.1e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HLNCHOAK_02971 1.2e-17 S Protein of unknown function (DUF3813)
HLNCHOAK_02972 5e-73 ipi S Intracellular proteinase inhibitor
HLNCHOAK_02973 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HLNCHOAK_02974 1.1e-308 nprB 3.4.24.28 E Peptidase M4
HLNCHOAK_02975 1.4e-44 yitR S Domain of unknown function (DUF3784)
HLNCHOAK_02976 2.5e-93
HLNCHOAK_02977 1.5e-58 K Transcriptional regulator PadR-like family
HLNCHOAK_02978 1.5e-97 S Sporulation delaying protein SdpA
HLNCHOAK_02979 3.6e-171
HLNCHOAK_02980 8.5e-94
HLNCHOAK_02981 3.4e-160 cvfB S protein conserved in bacteria
HLNCHOAK_02982 5.6e-54 yajQ S Belongs to the UPF0234 family
HLNCHOAK_02983 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HLNCHOAK_02984 3e-70 yjcF S Acetyltransferase (GNAT) domain
HLNCHOAK_02985 2.5e-150 yitH K Acetyltransferase (GNAT) domain
HLNCHOAK_02986 2e-228 yitG EGP Major facilitator Superfamily
HLNCHOAK_02987 1.6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HLNCHOAK_02988 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLNCHOAK_02989 1.6e-140 yitD 4.4.1.19 S synthase
HLNCHOAK_02990 4.9e-117 comB 3.1.3.71 H Belongs to the ComB family
HLNCHOAK_02991 7.3e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HLNCHOAK_02992 1.9e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HLNCHOAK_02993 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HLNCHOAK_02994 2.7e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLNCHOAK_02995 2e-35 mcbG S Pentapeptide repeats (9 copies)
HLNCHOAK_02996 2.4e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLNCHOAK_02997 2.7e-106 argO S Lysine exporter protein LysE YggA
HLNCHOAK_02998 1.8e-92 yisT S DinB family
HLNCHOAK_02999 2.2e-190 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HLNCHOAK_03000 5.8e-183 purR K helix_turn _helix lactose operon repressor
HLNCHOAK_03001 1.2e-160 yisR K Transcriptional regulator
HLNCHOAK_03002 4e-243 yisQ V Mate efflux family protein
HLNCHOAK_03003 1.9e-123 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HLNCHOAK_03004 0.0 asnO 6.3.5.4 E Asparagine synthase
HLNCHOAK_03005 6.9e-101 yisN S Protein of unknown function (DUF2777)
HLNCHOAK_03006 0.0 wprA O Belongs to the peptidase S8 family
HLNCHOAK_03007 3e-57 yisL S UPF0344 protein
HLNCHOAK_03008 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HLNCHOAK_03009 3.1e-175 cotH M Spore Coat
HLNCHOAK_03010 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HLNCHOAK_03011 1.9e-33 gerPA S Spore germination protein
HLNCHOAK_03012 1.6e-30 gerPB S cell differentiation
HLNCHOAK_03013 5.3e-54 gerPC S Spore germination protein
HLNCHOAK_03014 3.1e-23 gerPD S Spore germination protein
HLNCHOAK_03015 1.3e-64 gerPE S Spore germination protein GerPE
HLNCHOAK_03016 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HLNCHOAK_03017 3.3e-49 yisB V COG1403 Restriction endonuclease
HLNCHOAK_03018 0.0 sbcC L COG0419 ATPase involved in DNA repair
HLNCHOAK_03019 2.6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLNCHOAK_03020 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HLNCHOAK_03021 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HLNCHOAK_03022 0.0 S Sugar transport-related sRNA regulator N-term
HLNCHOAK_03023 4.6e-211 EGP Transmembrane secretion effector
HLNCHOAK_03024 1.2e-200 abrB S membrane
HLNCHOAK_03025 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
HLNCHOAK_03026 4.1e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HLNCHOAK_03027 4e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HLNCHOAK_03028 1.8e-198 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HLNCHOAK_03029 1.9e-212 glcP G Major Facilitator Superfamily
HLNCHOAK_03032 1.2e-91 yhjH K helix_turn_helix multiple antibiotic resistance protein
HLNCHOAK_03033 2.8e-282 yhjG CH FAD binding domain
HLNCHOAK_03034 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HLNCHOAK_03035 9.1e-110 yhjE S SNARE associated Golgi protein
HLNCHOAK_03036 6.7e-60 yhjD
HLNCHOAK_03037 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HLNCHOAK_03038 5.7e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLNCHOAK_03039 3.9e-41 yhjA S Excalibur calcium-binding domain
HLNCHOAK_03040 8e-168 IQ Enoyl-(Acyl carrier protein) reductase
HLNCHOAK_03041 9.3e-109 comK K Competence transcription factor
HLNCHOAK_03042 1.3e-32 yhzC S IDEAL
HLNCHOAK_03043 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_03044 8e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HLNCHOAK_03045 1.7e-182 hemAT NT chemotaxis protein
HLNCHOAK_03046 5e-91 bioY S BioY family
HLNCHOAK_03047 6.8e-278 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HLNCHOAK_03048 2e-200 vraB 2.3.1.9 I Belongs to the thiolase family
HLNCHOAK_03049 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HLNCHOAK_03050 2.1e-158 yfmC M Periplasmic binding protein
HLNCHOAK_03051 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HLNCHOAK_03052 1.1e-77 VY92_01935 K acetyltransferase
HLNCHOAK_03053 1.8e-196 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HLNCHOAK_03054 5.3e-237 yhfN 3.4.24.84 O Peptidase M48
HLNCHOAK_03055 1.9e-65 yhfM
HLNCHOAK_03056 1.3e-301 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HLNCHOAK_03057 2.6e-112 yhfK GM NmrA-like family
HLNCHOAK_03058 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HLNCHOAK_03059 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HLNCHOAK_03060 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLNCHOAK_03061 3.7e-72 3.4.13.21 S ASCH
HLNCHOAK_03062 3.9e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HLNCHOAK_03063 1.4e-136 yhfC S Putative membrane peptidase family (DUF2324)
HLNCHOAK_03064 4.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLNCHOAK_03065 1.6e-215 yhgE S YhgE Pip N-terminal domain protein
HLNCHOAK_03066 5.4e-101 yhgD K Transcriptional regulator
HLNCHOAK_03067 4.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HLNCHOAK_03068 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HLNCHOAK_03069 1.4e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HLNCHOAK_03070 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HLNCHOAK_03071 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HLNCHOAK_03072 4.6e-33 1.15.1.2 C Rubrerythrin
HLNCHOAK_03073 1.7e-241 yhfA C membrane
HLNCHOAK_03074 5.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HLNCHOAK_03075 4.6e-110 ecsC S EcsC protein family
HLNCHOAK_03076 2e-214 ecsB U ABC transporter
HLNCHOAK_03077 4.6e-137 ecsA V transporter (ATP-binding protein)
HLNCHOAK_03078 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HLNCHOAK_03079 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HLNCHOAK_03080 3.6e-80 trpP S Tryptophan transporter TrpP
HLNCHOAK_03081 5.4e-21
HLNCHOAK_03082 8.2e-39 yhaH S YtxH-like protein
HLNCHOAK_03083 1e-113 hpr K Negative regulator of protease production and sporulation
HLNCHOAK_03084 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HLNCHOAK_03085 8.7e-90 yhaK S Putative zincin peptidase
HLNCHOAK_03086 1.6e-120 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLNCHOAK_03087 1.6e-21 yhaL S Sporulation protein YhaL
HLNCHOAK_03088 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HLNCHOAK_03089 0.0 yhaN L AAA domain
HLNCHOAK_03090 3.1e-223 yhaO L DNA repair exonuclease
HLNCHOAK_03091 1.6e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HLNCHOAK_03092 5.7e-166 yhaQ S ABC transporter, ATP-binding protein
HLNCHOAK_03093 9.2e-26 S YhzD-like protein
HLNCHOAK_03094 1e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
HLNCHOAK_03096 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HLNCHOAK_03097 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HLNCHOAK_03098 1.5e-291 hemZ H coproporphyrinogen III oxidase
HLNCHOAK_03099 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HLNCHOAK_03100 9.8e-205 yhaZ L DNA alkylation repair enzyme
HLNCHOAK_03101 9.5e-48 yheA S Belongs to the UPF0342 family
HLNCHOAK_03102 2.2e-202 yheB S Belongs to the UPF0754 family
HLNCHOAK_03103 2.4e-214 yheC HJ YheC/D like ATP-grasp
HLNCHOAK_03104 3.3e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HLNCHOAK_03105 1.3e-36 yheE S Family of unknown function (DUF5342)
HLNCHOAK_03106 6.3e-28 sspB S spore protein
HLNCHOAK_03107 1.1e-72 yheG GM NAD(P)H-binding
HLNCHOAK_03108 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HLNCHOAK_03109 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HLNCHOAK_03110 8.4e-83 nhaX T Belongs to the universal stress protein A family
HLNCHOAK_03111 9.5e-229 nhaC C Na H antiporter
HLNCHOAK_03112 4e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HLNCHOAK_03113 1.9e-147 yheN G deacetylase
HLNCHOAK_03114 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HLNCHOAK_03115 9.9e-184 yhdY M Mechanosensitive ion channel
HLNCHOAK_03117 8.9e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HLNCHOAK_03118 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLNCHOAK_03119 1.6e-42 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLNCHOAK_03120 8.7e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HLNCHOAK_03121 8.8e-223 yhdR 2.6.1.1 E Aminotransferase
HLNCHOAK_03122 4.1e-74 cueR K transcriptional
HLNCHOAK_03123 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HLNCHOAK_03124 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HLNCHOAK_03125 1.5e-191 yhdN C Aldo keto reductase
HLNCHOAK_03126 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HLNCHOAK_03127 6.6e-201 yhdL S Sigma factor regulator N-terminal
HLNCHOAK_03128 8.1e-45 yhdK S Sigma-M inhibitor protein
HLNCHOAK_03129 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLNCHOAK_03130 7.4e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLNCHOAK_03131 3.7e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HLNCHOAK_03132 1e-249 yhdG E amino acid
HLNCHOAK_03133 6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_03134 2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
HLNCHOAK_03135 3.8e-162 citR K Transcriptional regulator
HLNCHOAK_03136 3.6e-140 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HLNCHOAK_03137 2.7e-255 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HLNCHOAK_03138 2.1e-276 ycgB S Stage V sporulation protein R
HLNCHOAK_03139 1.5e-238 ygxB M Conserved TM helix
HLNCHOAK_03140 1e-75 nsrR K Transcriptional regulator
HLNCHOAK_03141 2e-184 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HLNCHOAK_03142 2e-52 yhdC S Protein of unknown function (DUF3889)
HLNCHOAK_03143 1.2e-38 yhdB S YhdB-like protein
HLNCHOAK_03144 7.9e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
HLNCHOAK_03145 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLNCHOAK_03146 6.1e-213 yhcY 2.7.13.3 T Histidine kinase
HLNCHOAK_03147 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HLNCHOAK_03148 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HLNCHOAK_03149 1e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLNCHOAK_03150 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HLNCHOAK_03151 1.2e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HLNCHOAK_03152 6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLNCHOAK_03153 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HLNCHOAK_03154 6e-120 yhcW 5.4.2.6 S hydrolase
HLNCHOAK_03155 9.9e-68 yhcV S COG0517 FOG CBS domain
HLNCHOAK_03156 2.1e-67 yhcU S Family of unknown function (DUF5365)
HLNCHOAK_03157 9.6e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HLNCHOAK_03158 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HLNCHOAK_03159 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HLNCHOAK_03160 5.2e-100 yhcQ M Spore coat protein
HLNCHOAK_03161 8.1e-166 yhcP
HLNCHOAK_03162 2.2e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLNCHOAK_03163 9.2e-40 yhcM
HLNCHOAK_03164 1.2e-49 K Transcriptional regulator PadR-like family
HLNCHOAK_03165 3.2e-77 S Protein of unknown function (DUF2812)
HLNCHOAK_03166 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLNCHOAK_03167 2.4e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HLNCHOAK_03168 1.6e-149 metQ M Belongs to the nlpA lipoprotein family
HLNCHOAK_03169 1e-30 cspB K Cold-shock protein
HLNCHOAK_03170 1.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLNCHOAK_03171 3.2e-164 yhcH V ABC transporter, ATP-binding protein
HLNCHOAK_03172 4e-122 yhcG V ABC transporter, ATP-binding protein
HLNCHOAK_03173 6.6e-60 yhcF K Transcriptional regulator
HLNCHOAK_03174 6e-55
HLNCHOAK_03175 2.8e-37 yhcC
HLNCHOAK_03176 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HLNCHOAK_03177 2.9e-269 yhcA EGP Major facilitator Superfamily
HLNCHOAK_03178 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HLNCHOAK_03179 2.2e-76 yhbI K DNA-binding transcription factor activity
HLNCHOAK_03180 2.5e-225 yhbH S Belongs to the UPF0229 family
HLNCHOAK_03181 0.0 prkA T Ser protein kinase
HLNCHOAK_03182 1.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HLNCHOAK_03183 7.8e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HLNCHOAK_03184 1.2e-109 yhbD K Protein of unknown function (DUF4004)
HLNCHOAK_03185 3.1e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLNCHOAK_03186 1.7e-176 yhbB S Putative amidase domain
HLNCHOAK_03187 3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HLNCHOAK_03188 8.7e-113 yhzB S B3/4 domain
HLNCHOAK_03190 2.2e-28 K Transcriptional regulator
HLNCHOAK_03191 5.5e-75 ygaO
HLNCHOAK_03192 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLNCHOAK_03194 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HLNCHOAK_03195 8e-146 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HLNCHOAK_03196 5.2e-168 ssuA M Sulfonate ABC transporter
HLNCHOAK_03197 8.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HLNCHOAK_03198 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HLNCHOAK_03200 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HLNCHOAK_03201 2.7e-129 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HLNCHOAK_03202 1.2e-26
HLNCHOAK_03203 5e-142 spo0M S COG4326 Sporulation control protein
HLNCHOAK_03205 7.8e-08
HLNCHOAK_03207 2.5e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HLNCHOAK_03208 4.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HLNCHOAK_03209 1.9e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HLNCHOAK_03210 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HLNCHOAK_03211 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLNCHOAK_03212 0.0 ydiF S ABC transporter
HLNCHOAK_03213 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HLNCHOAK_03214 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLNCHOAK_03215 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HLNCHOAK_03216 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLNCHOAK_03217 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HLNCHOAK_03218 1e-128 ydiL S CAAX protease self-immunity
HLNCHOAK_03219 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLNCHOAK_03220 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLNCHOAK_03222 1.5e-151 ydjC S Abhydrolase domain containing 18
HLNCHOAK_03223 0.0 K NB-ARC domain
HLNCHOAK_03224 4.7e-199 gutB 1.1.1.14 E Dehydrogenase
HLNCHOAK_03225 3.1e-251 gutA G MFS/sugar transport protein
HLNCHOAK_03226 2e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HLNCHOAK_03227 1.1e-113 pspA KT Phage shock protein A
HLNCHOAK_03228 3.7e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLNCHOAK_03229 2.6e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HLNCHOAK_03230 1.8e-149 ydjI S virion core protein (lumpy skin disease virus)
HLNCHOAK_03231 3.3e-194 S Ion transport 2 domain protein
HLNCHOAK_03232 5.9e-258 iolT EGP Major facilitator Superfamily
HLNCHOAK_03233 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HLNCHOAK_03234 4.5e-64 ydjM M Lytic transglycolase
HLNCHOAK_03235 3.7e-156 ydjN U Involved in the tonB-independent uptake of proteins
HLNCHOAK_03237 1.2e-34 ydjO S Cold-inducible protein YdjO
HLNCHOAK_03238 2.9e-156 ydjP I Alpha/beta hydrolase family
HLNCHOAK_03239 1e-176 yeaA S Protein of unknown function (DUF4003)
HLNCHOAK_03240 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HLNCHOAK_03241 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HLNCHOAK_03242 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLNCHOAK_03243 1.5e-175 yeaC S COG0714 MoxR-like ATPases
HLNCHOAK_03244 1.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HLNCHOAK_03245 0.0 yebA E COG1305 Transglutaminase-like enzymes
HLNCHOAK_03246 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HLNCHOAK_03247 1.2e-83 K Belongs to the sigma-70 factor family. ECF subfamily
HLNCHOAK_03248 2.8e-255 S Domain of unknown function (DUF4179)
HLNCHOAK_03249 5.1e-211 pbuG S permease
HLNCHOAK_03250 2.3e-118 yebC M Membrane
HLNCHOAK_03252 8.9e-93 yebE S UPF0316 protein
HLNCHOAK_03253 8e-28 yebG S NETI protein
HLNCHOAK_03254 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLNCHOAK_03255 3.3e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLNCHOAK_03256 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLNCHOAK_03257 1.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HLNCHOAK_03258 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLNCHOAK_03259 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLNCHOAK_03260 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLNCHOAK_03261 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLNCHOAK_03262 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HLNCHOAK_03263 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLNCHOAK_03264 3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HLNCHOAK_03265 1.7e-232 purD 6.3.4.13 F Belongs to the GARS family
HLNCHOAK_03266 1.9e-71 K helix_turn_helix ASNC type
HLNCHOAK_03267 2.3e-229 yjeH E Amino acid permease
HLNCHOAK_03268 2.7e-27 S Protein of unknown function (DUF2892)
HLNCHOAK_03269 0.0 yerA 3.5.4.2 F adenine deaminase
HLNCHOAK_03270 1.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
HLNCHOAK_03271 4.8e-51 yerC S protein conserved in bacteria
HLNCHOAK_03272 9.7e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HLNCHOAK_03274 1.4e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HLNCHOAK_03275 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HLNCHOAK_03276 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLNCHOAK_03277 3e-218 camS S COG4851 Protein involved in sex pheromone biosynthesis
HLNCHOAK_03278 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
HLNCHOAK_03279 1.6e-123 sapB S MgtC SapB transporter
HLNCHOAK_03280 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLNCHOAK_03281 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLNCHOAK_03282 5.6e-08 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLNCHOAK_03283 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLNCHOAK_03284 3.4e-144 yerO K Transcriptional regulator
HLNCHOAK_03285 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HLNCHOAK_03286 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HLNCHOAK_03287 4.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLNCHOAK_03288 2.6e-37 L Recombinase zinc beta ribbon domain
HLNCHOAK_03290 7.5e-113 KLT Protein tyrosine kinase
HLNCHOAK_03291 1e-46 tehB 2.1.1.265 Q Domain of unknown function (DUF4062)
HLNCHOAK_03292 1.7e-113 S Domain of unknown function (DUF4935)
HLNCHOAK_03294 1.4e-40 S response regulator aspartate phosphatase
HLNCHOAK_03295 3e-48 S Tetratricopeptide repeat
HLNCHOAK_03297 5.1e-42 S Immunity protein 22
HLNCHOAK_03298 9.5e-187 yobL S Bacterial EndoU nuclease
HLNCHOAK_03300 5.1e-101 L endonuclease activity
HLNCHOAK_03301 4.8e-169 3.4.24.40 CO amine dehydrogenase activity
HLNCHOAK_03302 1.1e-209 S Tetratricopeptide repeat
HLNCHOAK_03304 2.7e-126 yeeN K transcriptional regulatory protein
HLNCHOAK_03306 3.6e-100 dhaR3 K Transcriptional regulator
HLNCHOAK_03307 3.4e-79 yesE S SnoaL-like domain
HLNCHOAK_03308 5.5e-150 yesF GM NAD(P)H-binding
HLNCHOAK_03309 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HLNCHOAK_03310 1.5e-45 cotJB S CotJB protein
HLNCHOAK_03311 5.2e-104 cotJC P Spore Coat
HLNCHOAK_03312 6e-102 yesJ K Acetyltransferase (GNAT) family
HLNCHOAK_03314 2.2e-100 yesL S Protein of unknown function, DUF624
HLNCHOAK_03315 0.0 yesM 2.7.13.3 T Histidine kinase
HLNCHOAK_03316 6.1e-202 yesN K helix_turn_helix, arabinose operon control protein
HLNCHOAK_03317 3.3e-247 yesO G Bacterial extracellular solute-binding protein
HLNCHOAK_03318 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HLNCHOAK_03319 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
HLNCHOAK_03320 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HLNCHOAK_03321 0.0 yesS K Transcriptional regulator
HLNCHOAK_03322 1.6e-131 E GDSL-like Lipase/Acylhydrolase
HLNCHOAK_03323 3.8e-130 yesU S Domain of unknown function (DUF1961)
HLNCHOAK_03324 3e-113 yesV S Protein of unknown function, DUF624
HLNCHOAK_03325 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HLNCHOAK_03326 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HLNCHOAK_03327 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
HLNCHOAK_03328 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HLNCHOAK_03329 0.0 yetA
HLNCHOAK_03330 6.2e-290 lplA G Bacterial extracellular solute-binding protein
HLNCHOAK_03331 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HLNCHOAK_03332 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HLNCHOAK_03333 1.7e-254 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HLNCHOAK_03334 5.2e-122 yetF S membrane
HLNCHOAK_03335 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HLNCHOAK_03336 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLNCHOAK_03337 2.8e-27
HLNCHOAK_03338 6e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLNCHOAK_03339 2e-19 yezD S Uncharacterized small protein (DUF2292)
HLNCHOAK_03340 9.1e-105 yetJ S Belongs to the BI1 family
HLNCHOAK_03341 6.8e-08 yetL K helix_turn_helix multiple antibiotic resistance protein
HLNCHOAK_03342 2.1e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
HLNCHOAK_03343 2.6e-208 yetM CH FAD binding domain
HLNCHOAK_03345 1e-193 yetN S Protein of unknown function (DUF3900)
HLNCHOAK_03346 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HLNCHOAK_03347 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HLNCHOAK_03348 4.3e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
HLNCHOAK_03349 3.2e-172 yfnG 4.2.1.45 M dehydratase
HLNCHOAK_03350 9.3e-180 yfnF M Nucleotide-diphospho-sugar transferase
HLNCHOAK_03351 2.1e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HLNCHOAK_03352 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
HLNCHOAK_03353 8.6e-205 fsr P COG0477 Permeases of the major facilitator superfamily
HLNCHOAK_03354 3.4e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HLNCHOAK_03355 6.4e-241 yfnA E amino acid
HLNCHOAK_03356 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLNCHOAK_03357 1.1e-113 yfmS NT chemotaxis protein
HLNCHOAK_03358 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLNCHOAK_03359 2.8e-73 yfmQ S Uncharacterised protein from bacillus cereus group
HLNCHOAK_03360 1.4e-69 yfmP K transcriptional
HLNCHOAK_03361 6.2e-208 yfmO EGP Major facilitator Superfamily
HLNCHOAK_03362 1.6e-59 isp O Subtilase family
HLNCHOAK_03363 6.4e-19
HLNCHOAK_03365 6.3e-57
HLNCHOAK_03366 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLNCHOAK_03367 4.5e-200 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HLNCHOAK_03368 6.8e-75 yfmK 2.3.1.128 K acetyltransferase
HLNCHOAK_03369 3.9e-187 yfmJ S N-terminal domain of oxidoreductase
HLNCHOAK_03370 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HLNCHOAK_03371 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_03372 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_03373 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HLNCHOAK_03374 5e-24 S Protein of unknown function (DUF3212)
HLNCHOAK_03375 7.6e-58 yflT S Heat induced stress protein YflT
HLNCHOAK_03376 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HLNCHOAK_03377 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
HLNCHOAK_03378 3.7e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HLNCHOAK_03379 5.8e-118 citT T response regulator
HLNCHOAK_03380 1.7e-179 yflP S Tripartite tricarboxylate transporter family receptor
HLNCHOAK_03381 1.4e-226 citM C Citrate transporter
HLNCHOAK_03382 1.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HLNCHOAK_03383 2.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HLNCHOAK_03384 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HLNCHOAK_03385 3.5e-39 yflK S protein conserved in bacteria
HLNCHOAK_03386 8.9e-18 yflJ S Protein of unknown function (DUF2639)
HLNCHOAK_03387 4.1e-19 yflI
HLNCHOAK_03388 2.4e-50 yflH S Protein of unknown function (DUF3243)
HLNCHOAK_03389 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HLNCHOAK_03390 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HLNCHOAK_03391 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HLNCHOAK_03392 6e-67 yhdN S Domain of unknown function (DUF1992)
HLNCHOAK_03393 2.2e-252 agcS_1 E Sodium alanine symporter
HLNCHOAK_03394 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HLNCHOAK_03395 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HLNCHOAK_03396 3.9e-133 treR K transcriptional
HLNCHOAK_03397 1.1e-124 yfkO C nitroreductase
HLNCHOAK_03398 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HLNCHOAK_03399 3.3e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
HLNCHOAK_03400 3.4e-206 ydiM EGP Major facilitator Superfamily
HLNCHOAK_03401 2.1e-29 yfkK S Belongs to the UPF0435 family
HLNCHOAK_03402 2e-26 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLNCHOAK_03403 3.8e-41 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLNCHOAK_03404 2.4e-50 yfkI S gas vesicle protein
HLNCHOAK_03405 1.3e-143 yihY S Belongs to the UPF0761 family
HLNCHOAK_03406 5e-08
HLNCHOAK_03407 4.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HLNCHOAK_03408 1.8e-182 cax P COG0387 Ca2 H antiporter
HLNCHOAK_03409 1.2e-146 yfkD S YfkD-like protein
HLNCHOAK_03410 6e-149 yfkC M Mechanosensitive ion channel
HLNCHOAK_03411 5.4e-222 yfkA S YfkB-like domain
HLNCHOAK_03412 1.1e-26 yfjT
HLNCHOAK_03413 1.7e-153 pdaA G deacetylase
HLNCHOAK_03414 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HLNCHOAK_03415 1.7e-184 corA P Mediates influx of magnesium ions
HLNCHOAK_03416 3.8e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HLNCHOAK_03417 5.3e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLNCHOAK_03418 3.9e-44 S YfzA-like protein
HLNCHOAK_03419 1.2e-188 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLNCHOAK_03420 7.3e-85 yfjM S Psort location Cytoplasmic, score
HLNCHOAK_03421 3e-29 yfjL
HLNCHOAK_03422 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLNCHOAK_03423 8.5e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLNCHOAK_03424 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLNCHOAK_03425 4.7e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLNCHOAK_03426 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HLNCHOAK_03427 1.2e-25 sspH S Belongs to the SspH family
HLNCHOAK_03428 5.2e-56 yfjF S UPF0060 membrane protein
HLNCHOAK_03429 4.2e-79 S Family of unknown function (DUF5381)
HLNCHOAK_03430 1.1e-98 yfjD S Family of unknown function (DUF5381)
HLNCHOAK_03431 4.1e-144 yfjC
HLNCHOAK_03432 2.7e-190 yfjB
HLNCHOAK_03433 2.6e-44 yfjA S Belongs to the WXG100 family
HLNCHOAK_03434 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HLNCHOAK_03435 4.6e-140 glvR K Helix-turn-helix domain, rpiR family
HLNCHOAK_03436 1.4e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HLNCHOAK_03437 0.0 yobO M COG5434 Endopolygalacturonase
HLNCHOAK_03438 4.9e-307 yfiB3 V ABC transporter
HLNCHOAK_03439 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HLNCHOAK_03440 9.8e-65 mhqP S DoxX
HLNCHOAK_03441 1.3e-159 yfiE 1.13.11.2 S glyoxalase
HLNCHOAK_03442 3.4e-187 yxjM T Histidine kinase
HLNCHOAK_03443 2.8e-109 KT LuxR family transcriptional regulator
HLNCHOAK_03444 3.8e-168 V ABC transporter, ATP-binding protein
HLNCHOAK_03445 3.4e-206 V ABC-2 family transporter protein
HLNCHOAK_03446 6.3e-166 V COG0842 ABC-type multidrug transport system, permease component
HLNCHOAK_03447 3.6e-28 V COG0842 ABC-type multidrug transport system, permease component
HLNCHOAK_03448 4.1e-98 padR K transcriptional
HLNCHOAK_03449 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HLNCHOAK_03450 1.1e-195 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HLNCHOAK_03451 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
HLNCHOAK_03452 3.4e-283 yfiU EGP Major facilitator Superfamily
HLNCHOAK_03453 4.9e-79 yfiV K transcriptional
HLNCHOAK_03454 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLNCHOAK_03455 2.8e-174 yfiY P ABC transporter substrate-binding protein
HLNCHOAK_03456 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_03457 2.6e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_03458 2.8e-165 yfhB 5.3.3.17 S PhzF family
HLNCHOAK_03459 1.5e-106 yfhC C nitroreductase
HLNCHOAK_03460 2.1e-25 yfhD S YfhD-like protein
HLNCHOAK_03462 2.7e-171 yfhF S nucleoside-diphosphate sugar epimerase
HLNCHOAK_03463 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HLNCHOAK_03464 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HLNCHOAK_03466 2.5e-209 yfhI EGP Major facilitator Superfamily
HLNCHOAK_03467 6.2e-20 sspK S reproduction
HLNCHOAK_03468 1.3e-44 yfhJ S WVELL protein
HLNCHOAK_03469 7.8e-91 batE T Bacterial SH3 domain homologues
HLNCHOAK_03470 6.6e-50 yfhL S SdpI/YhfL protein family
HLNCHOAK_03471 3.7e-170 yfhM S Alpha beta hydrolase
HLNCHOAK_03472 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HLNCHOAK_03473 0.0 yfhO S Bacterial membrane protein YfhO
HLNCHOAK_03474 1.2e-185 yfhP S membrane-bound metal-dependent
HLNCHOAK_03475 3.3e-210 mutY L A G-specific
HLNCHOAK_03476 6.9e-36 yfhS
HLNCHOAK_03477 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_03478 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HLNCHOAK_03479 3.3e-37 ygaB S YgaB-like protein
HLNCHOAK_03480 1.3e-104 ygaC J Belongs to the UPF0374 family
HLNCHOAK_03481 1.2e-300 ygaD V ABC transporter
HLNCHOAK_03482 8.7e-180 ygaE S Membrane
HLNCHOAK_03483 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HLNCHOAK_03484 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
HLNCHOAK_03485 4e-80 perR P Belongs to the Fur family
HLNCHOAK_03486 2.8e-55 ygzB S UPF0295 protein
HLNCHOAK_03487 6.7e-167 ygxA S Nucleotidyltransferase-like
HLNCHOAK_03488 4.5e-233 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLNCHOAK_03489 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HLNCHOAK_03490 7.5e-140 srfAD Q thioesterase
HLNCHOAK_03491 1.2e-225 EGP Major Facilitator Superfamily
HLNCHOAK_03492 1.8e-88 S YcxB-like protein
HLNCHOAK_03493 2.4e-159 ycxC EG EamA-like transporter family
HLNCHOAK_03494 4.1e-253 ycxD K GntR family transcriptional regulator
HLNCHOAK_03495 1.7e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HLNCHOAK_03496 1.7e-114 yczE S membrane
HLNCHOAK_03497 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HLNCHOAK_03498 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HLNCHOAK_03499 2e-125 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HLNCHOAK_03500 1.9e-161 bsdA K LysR substrate binding domain
HLNCHOAK_03501 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HLNCHOAK_03502 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HLNCHOAK_03503 4e-39 bsdD 4.1.1.61 S response to toxic substance
HLNCHOAK_03504 3.5e-82 yclD
HLNCHOAK_03505 4.2e-158 yclE 3.4.11.5 S Alpha beta hydrolase
HLNCHOAK_03506 5.2e-265 dtpT E amino acid peptide transporter
HLNCHOAK_03507 3.3e-298 yclG M Pectate lyase superfamily protein
HLNCHOAK_03509 1.7e-277 gerKA EG Spore germination protein
HLNCHOAK_03510 1.6e-230 gerKC S spore germination
HLNCHOAK_03511 3e-196 gerKB F Spore germination protein
HLNCHOAK_03512 7.3e-121 yclH P ABC transporter
HLNCHOAK_03513 3.7e-202 yclI V ABC transporter (permease) YclI
HLNCHOAK_03514 2.1e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_03515 1.4e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HLNCHOAK_03516 1.3e-77 S aspartate phosphatase
HLNCHOAK_03520 7.5e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
HLNCHOAK_03521 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_03522 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_03523 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HLNCHOAK_03524 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HLNCHOAK_03525 1.2e-250 ycnB EGP Major facilitator Superfamily
HLNCHOAK_03526 6.5e-154 ycnC K Transcriptional regulator
HLNCHOAK_03527 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HLNCHOAK_03528 4.7e-45 ycnE S Monooxygenase
HLNCHOAK_03529 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HLNCHOAK_03530 1.1e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLNCHOAK_03531 2.8e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLNCHOAK_03532 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLNCHOAK_03533 6.1e-149 glcU U Glucose uptake
HLNCHOAK_03534 3.5e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_03535 5.4e-99 ycnI S protein conserved in bacteria
HLNCHOAK_03536 3.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
HLNCHOAK_03537 3.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HLNCHOAK_03538 2.6e-53
HLNCHOAK_03539 2.8e-239 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HLNCHOAK_03540 5.7e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HLNCHOAK_03541 1.4e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HLNCHOAK_03542 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HLNCHOAK_03543 2.1e-09 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HLNCHOAK_03544 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HLNCHOAK_03545 1.3e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HLNCHOAK_03546 6e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HLNCHOAK_03548 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HLNCHOAK_03549 8.8e-139 ycsF S Belongs to the UPF0271 (lamB) family
HLNCHOAK_03550 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HLNCHOAK_03551 9e-147 ycsI S Belongs to the D-glutamate cyclase family
HLNCHOAK_03552 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HLNCHOAK_03553 7.3e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HLNCHOAK_03554 3.5e-132 kipR K Transcriptional regulator
HLNCHOAK_03555 1.3e-116 ycsK E anatomical structure formation involved in morphogenesis
HLNCHOAK_03557 5.4e-49 yczJ S biosynthesis
HLNCHOAK_03558 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HLNCHOAK_03559 9.8e-174 ydhF S Oxidoreductase
HLNCHOAK_03560 0.0 mtlR K transcriptional regulator, MtlR
HLNCHOAK_03561 8.7e-292 ydaB IQ acyl-CoA ligase
HLNCHOAK_03562 3.1e-99 ydaC Q Methyltransferase domain
HLNCHOAK_03563 3.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLNCHOAK_03564 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HLNCHOAK_03565 5.6e-103 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLNCHOAK_03566 4.4e-76 ydaG 1.4.3.5 S general stress protein
HLNCHOAK_03567 9.2e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HLNCHOAK_03568 3.6e-45 ydzA EGP Major facilitator Superfamily
HLNCHOAK_03569 2.5e-74 lrpC K Transcriptional regulator
HLNCHOAK_03570 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLNCHOAK_03571 4.5e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HLNCHOAK_03572 9.4e-150 ydaK T Diguanylate cyclase, GGDEF domain
HLNCHOAK_03573 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HLNCHOAK_03574 1.3e-232 ydaM M Glycosyl transferase family group 2
HLNCHOAK_03575 0.0 ydaN S Bacterial cellulose synthase subunit
HLNCHOAK_03576 0.0 ydaO E amino acid
HLNCHOAK_03577 2.5e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HLNCHOAK_03578 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HLNCHOAK_03580 2.1e-39
HLNCHOAK_03581 1.7e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HLNCHOAK_03583 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HLNCHOAK_03584 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HLNCHOAK_03586 3.1e-56 ydbB G Cupin domain
HLNCHOAK_03587 1.8e-62 ydbC S Domain of unknown function (DUF4937
HLNCHOAK_03588 3.5e-154 ydbD P Catalase
HLNCHOAK_03589 1.3e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HLNCHOAK_03590 1.6e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HLNCHOAK_03591 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HLNCHOAK_03592 4.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLNCHOAK_03593 3.7e-180 ydbI S AI-2E family transporter
HLNCHOAK_03594 8e-171 ydbJ V ABC transporter, ATP-binding protein
HLNCHOAK_03595 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLNCHOAK_03596 2.7e-52 ydbL
HLNCHOAK_03597 1.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HLNCHOAK_03598 1.1e-18 S Fur-regulated basic protein B
HLNCHOAK_03599 2.2e-07 S Fur-regulated basic protein A
HLNCHOAK_03600 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLNCHOAK_03601 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HLNCHOAK_03602 4.3e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HLNCHOAK_03603 2.7e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLNCHOAK_03604 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLNCHOAK_03605 2.1e-82 ydbS S Bacterial PH domain
HLNCHOAK_03606 1.1e-259 ydbT S Membrane
HLNCHOAK_03607 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HLNCHOAK_03608 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLNCHOAK_03609 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HLNCHOAK_03610 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLNCHOAK_03611 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HLNCHOAK_03612 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HLNCHOAK_03613 4.8e-143 rsbR T Positive regulator of sigma-B
HLNCHOAK_03614 5.2e-57 rsbS T antagonist
HLNCHOAK_03615 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HLNCHOAK_03616 3.5e-188 rsbU 3.1.3.3 KT phosphatase
HLNCHOAK_03617 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
HLNCHOAK_03618 7.8e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HLNCHOAK_03619 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLNCHOAK_03620 2.4e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HLNCHOAK_03621 0.0 yhgF K COG2183 Transcriptional accessory protein
HLNCHOAK_03622 3.4e-82 ydcK S Belongs to the SprT family
HLNCHOAK_03630 3.9e-187 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLNCHOAK_03631 2.4e-71 lrpA K transcriptional
HLNCHOAK_03632 1.9e-77 lrpB K transcriptional
HLNCHOAK_03633 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
HLNCHOAK_03634 1.7e-142 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HLNCHOAK_03635 4.2e-226 ydeG EGP Major facilitator Superfamily
HLNCHOAK_03636 2.5e-69 L HNH nucleases
HLNCHOAK_03637 2.8e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HLNCHOAK_03638 8.7e-30 cspL K Cold shock
HLNCHOAK_03639 6.1e-79 carD K Transcription factor
HLNCHOAK_03640 3.1e-30 ydzE EG spore germination
HLNCHOAK_03641 1.6e-160 rhaS5 K AraC-like ligand binding domain
HLNCHOAK_03642 3.4e-172 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HLNCHOAK_03643 3.6e-165 ydeE K AraC family transcriptional regulator
HLNCHOAK_03644 1.2e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLNCHOAK_03645 3.2e-218 ydeG EGP Major facilitator superfamily
HLNCHOAK_03646 1.4e-33 ydeH
HLNCHOAK_03647 2.3e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HLNCHOAK_03648 7.1e-113
HLNCHOAK_03649 1e-151 ydeK EG -transporter
HLNCHOAK_03650 1.3e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLNCHOAK_03651 2.7e-73 maoC I N-terminal half of MaoC dehydratase
HLNCHOAK_03652 8.4e-105 ydeN S Serine hydrolase
HLNCHOAK_03653 4.4e-55 K HxlR-like helix-turn-helix
HLNCHOAK_03654 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HLNCHOAK_03655 8.2e-57 arsR K transcriptional
HLNCHOAK_03656 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HLNCHOAK_03657 3.7e-145 ydfB J GNAT acetyltransferase
HLNCHOAK_03658 8.3e-149 lytR K Transcriptional regulator
HLNCHOAK_03659 7.7e-122 nodB1 G deacetylase
HLNCHOAK_03660 2.1e-157
HLNCHOAK_03661 5.9e-213 T GHKL domain
HLNCHOAK_03662 1.2e-121 T Transcriptional regulatory protein, C terminal
HLNCHOAK_03663 1.1e-145 ydfC EG EamA-like transporter family
HLNCHOAK_03664 7.9e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLNCHOAK_03665 1.2e-114 ydfE S Flavin reductase like domain
HLNCHOAK_03666 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HLNCHOAK_03667 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HLNCHOAK_03669 1.4e-177 ydfH 2.7.13.3 T Histidine kinase
HLNCHOAK_03670 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLNCHOAK_03671 0.0 ydfJ S drug exporters of the RND superfamily
HLNCHOAK_03672 8.5e-117 S Protein of unknown function (DUF554)
HLNCHOAK_03673 1.2e-143 K Bacterial transcription activator, effector binding domain
HLNCHOAK_03674 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLNCHOAK_03675 7.1e-107 ydfN C nitroreductase
HLNCHOAK_03676 8.9e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HLNCHOAK_03677 1.2e-62 mhqP S DoxX
HLNCHOAK_03678 5e-54 traF CO Thioredoxin
HLNCHOAK_03679 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HLNCHOAK_03680 8.2e-29
HLNCHOAK_03682 1.9e-45 ydfR S Protein of unknown function (DUF421)
HLNCHOAK_03683 2.3e-30 ydfR S Protein of unknown function (DUF421)
HLNCHOAK_03684 1.5e-121 ydfS S Protein of unknown function (DUF421)
HLNCHOAK_03685 1.1e-66 cotP O Belongs to the small heat shock protein (HSP20) family
HLNCHOAK_03686 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
HLNCHOAK_03687 2.7e-34 ydgB S Spore germination protein gerPA/gerPF
HLNCHOAK_03688 1.3e-97 K Bacterial regulatory proteins, tetR family
HLNCHOAK_03689 1.3e-52 S DoxX-like family
HLNCHOAK_03690 8.5e-84 yycN 2.3.1.128 K Acetyltransferase
HLNCHOAK_03691 5.4e-303 expZ S ABC transporter
HLNCHOAK_03692 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HLNCHOAK_03693 2.5e-89 dinB S DinB family
HLNCHOAK_03694 2.7e-79 K helix_turn_helix multiple antibiotic resistance protein
HLNCHOAK_03695 0.0 ydgH S drug exporters of the RND superfamily
HLNCHOAK_03696 1e-113 drgA C nitroreductase
HLNCHOAK_03697 2.4e-69 ydgJ K Winged helix DNA-binding domain
HLNCHOAK_03698 1.4e-207 tcaB EGP Major facilitator Superfamily
HLNCHOAK_03699 3.5e-121 ydhB S membrane transporter protein
HLNCHOAK_03700 2.5e-121 ydhC K FCD
HLNCHOAK_03701 4.1e-242 ydhD M Glycosyl hydrolase
HLNCHOAK_03702 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HLNCHOAK_03703 7.4e-124
HLNCHOAK_03704 2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HLNCHOAK_03705 1.6e-66 frataxin S Domain of unknown function (DU1801)
HLNCHOAK_03707 1.2e-80 K Acetyltransferase (GNAT) domain
HLNCHOAK_03708 1.7e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HLNCHOAK_03709 2.3e-96 ydhK M Protein of unknown function (DUF1541)
HLNCHOAK_03710 1.1e-198 pbuE EGP Major facilitator Superfamily
HLNCHOAK_03711 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HLNCHOAK_03712 9.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HLNCHOAK_03713 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLNCHOAK_03714 9.9e-282 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HLNCHOAK_03715 1.1e-132 ydhQ K UTRA
HLNCHOAK_03716 4.7e-168 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HLNCHOAK_03717 8.2e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HLNCHOAK_03718 7.1e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HLNCHOAK_03719 6.7e-156 ydhU P Catalase
HLNCHOAK_03722 1.3e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HLNCHOAK_03724 4.7e-158 ybaS 1.1.1.58 S Na -dependent transporter
HLNCHOAK_03725 3.7e-134 ybbA S Putative esterase
HLNCHOAK_03726 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_03727 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLNCHOAK_03728 1.4e-165 feuA P Iron-uptake system-binding protein
HLNCHOAK_03729 2e-302 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HLNCHOAK_03730 1.2e-238 ybbC 3.2.1.52 S protein conserved in bacteria
HLNCHOAK_03731 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HLNCHOAK_03732 3.8e-251 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HLNCHOAK_03733 3.2e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HLNCHOAK_03734 2.1e-149 ybbH K transcriptional
HLNCHOAK_03735 2.3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HLNCHOAK_03736 2.7e-85 ybbJ J acetyltransferase
HLNCHOAK_03737 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HLNCHOAK_03740 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HLNCHOAK_03741 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HLNCHOAK_03742 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLNCHOAK_03743 1.5e-224 ybbR S protein conserved in bacteria
HLNCHOAK_03744 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLNCHOAK_03745 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLNCHOAK_03746 1.4e-172 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HLNCHOAK_03747 6.7e-116 adaA 3.2.2.21 K Transcriptional regulator
HLNCHOAK_03748 1.8e-98 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLNCHOAK_03749 7e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HLNCHOAK_03750 0.0 ybcC S Belongs to the UPF0753 family
HLNCHOAK_03751 6.5e-93 can 4.2.1.1 P carbonic anhydrase
HLNCHOAK_03752 3.9e-47
HLNCHOAK_03753 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HLNCHOAK_03755 5.1e-50 ybzH K Helix-turn-helix domain
HLNCHOAK_03756 9.4e-201 ybcL EGP Major facilitator Superfamily
HLNCHOAK_03757 9.5e-56
HLNCHOAK_03758 5.3e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLNCHOAK_03759 4.5e-123 T Transcriptional regulatory protein, C terminal
HLNCHOAK_03760 1.1e-170 T His Kinase A (phospho-acceptor) domain
HLNCHOAK_03762 4.4e-138 KLT Protein tyrosine kinase
HLNCHOAK_03763 2.4e-201 ybdO S Domain of unknown function (DUF4885)
HLNCHOAK_03764 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HLNCHOAK_03765 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HLNCHOAK_03766 4.9e-30 ybxH S Family of unknown function (DUF5370)
HLNCHOAK_03767 1.3e-66 ybxI 3.5.2.6 V beta-lactamase
HLNCHOAK_03768 8.2e-48 ybxI 3.5.2.6 V beta-lactamase
HLNCHOAK_03769 3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HLNCHOAK_03770 4.9e-41 ybyB
HLNCHOAK_03771 1.8e-290 ybeC E amino acid
HLNCHOAK_03772 6.5e-162 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HLNCHOAK_03773 2.1e-257 glpT G -transporter
HLNCHOAK_03774 1.5e-34 S Protein of unknown function (DUF2651)
HLNCHOAK_03775 4.4e-169 ybfA 3.4.15.5 K FR47-like protein
HLNCHOAK_03776 7.9e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
HLNCHOAK_03778 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HLNCHOAK_03779 9.7e-161 ybfH EG EamA-like transporter family
HLNCHOAK_03780 3e-145 msmR K AraC-like ligand binding domain
HLNCHOAK_03781 5.2e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLNCHOAK_03782 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HLNCHOAK_03784 4.7e-168 S Alpha/beta hydrolase family
HLNCHOAK_03785 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLNCHOAK_03786 2.7e-85 ybfM S SNARE associated Golgi protein
HLNCHOAK_03787 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HLNCHOAK_03788 4.6e-45 ybfN
HLNCHOAK_03789 5.6e-250 S Erythromycin esterase
HLNCHOAK_03790 3.9e-192 yceA S Belongs to the UPF0176 family
HLNCHOAK_03791 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLNCHOAK_03792 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HLNCHOAK_03793 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLNCHOAK_03794 4.9e-128 K UTRA
HLNCHOAK_03796 3.9e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HLNCHOAK_03797 2.4e-259 mmuP E amino acid
HLNCHOAK_03798 2.1e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HLNCHOAK_03799 7.3e-256 agcS E Sodium alanine symporter
HLNCHOAK_03800 4.2e-186 glsA 3.5.1.2 E Belongs to the glutaminase family
HLNCHOAK_03801 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
HLNCHOAK_03802 4.5e-169 glnL T Regulator
HLNCHOAK_03803 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HLNCHOAK_03804 3.1e-273 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLNCHOAK_03805 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HLNCHOAK_03806 2.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HLNCHOAK_03807 2.1e-123 ycbG K FCD
HLNCHOAK_03808 2.9e-295 garD 4.2.1.42, 4.2.1.7 G Altronate
HLNCHOAK_03809 2.9e-173 ycbJ S Macrolide 2'-phosphotransferase
HLNCHOAK_03810 5.7e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HLNCHOAK_03811 1.2e-166 eamA1 EG spore germination
HLNCHOAK_03812 2.9e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLNCHOAK_03813 7.1e-167 T PhoQ Sensor
HLNCHOAK_03814 1.1e-164 ycbN V ABC transporter, ATP-binding protein
HLNCHOAK_03815 9.6e-113 S ABC-2 family transporter protein
HLNCHOAK_03816 4.1e-52 ycbP S Protein of unknown function (DUF2512)
HLNCHOAK_03817 2.2e-78 sleB 3.5.1.28 M Cell wall
HLNCHOAK_03818 9.5e-135 ycbR T vWA found in TerF C terminus
HLNCHOAK_03819 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HLNCHOAK_03820 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HLNCHOAK_03821 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLNCHOAK_03822 2.5e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HLNCHOAK_03823 2.3e-204 ycbU E Selenocysteine lyase
HLNCHOAK_03824 7.9e-226 lmrB EGP the major facilitator superfamily
HLNCHOAK_03825 4.8e-102 yxaF K Transcriptional regulator
HLNCHOAK_03826 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HLNCHOAK_03827 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HLNCHOAK_03828 6e-56 S RDD family
HLNCHOAK_03829 1.8e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
HLNCHOAK_03830 2e-156 2.7.13.3 T GHKL domain
HLNCHOAK_03831 7.1e-36 lytR_2 T LytTr DNA-binding domain
HLNCHOAK_03832 1.3e-76 lytR_2 T LytTr DNA-binding domain
HLNCHOAK_03833 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HLNCHOAK_03834 2.1e-200 natB CP ABC-2 family transporter protein
HLNCHOAK_03835 3.5e-174 yccK C Aldo keto reductase
HLNCHOAK_03836 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HLNCHOAK_03837 9.4e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HLNCHOAK_03838 3.7e-258 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HLNCHOAK_03839 1.8e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
HLNCHOAK_03840 2.7e-173 S response regulator aspartate phosphatase
HLNCHOAK_03841 6.8e-139 IQ Enoyl-(Acyl carrier protein) reductase
HLNCHOAK_03842 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HLNCHOAK_03843 1.1e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
HLNCHOAK_03844 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HLNCHOAK_03845 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HLNCHOAK_03846 9.5e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLNCHOAK_03847 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HLNCHOAK_03848 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HLNCHOAK_03849 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HLNCHOAK_03850 6.3e-137 terC P Protein of unknown function (DUF475)
HLNCHOAK_03851 0.0 yceG S Putative component of 'biosynthetic module'
HLNCHOAK_03852 2e-192 yceH P Belongs to the TelA family
HLNCHOAK_03853 4.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
HLNCHOAK_03854 1.5e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
HLNCHOAK_03855 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HLNCHOAK_03856 5.1e-229 proV 3.6.3.32 E glycine betaine
HLNCHOAK_03857 1.3e-127 opuAB P glycine betaine
HLNCHOAK_03858 5.3e-164 opuAC E glycine betaine
HLNCHOAK_03859 7.5e-219 amhX S amidohydrolase
HLNCHOAK_03860 1.1e-254 ycgA S Membrane
HLNCHOAK_03861 7e-81 ycgB
HLNCHOAK_03862 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HLNCHOAK_03863 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HLNCHOAK_03864 3.2e-292 lctP C L-lactate permease
HLNCHOAK_03865 1.1e-262 mdr EGP Major facilitator Superfamily
HLNCHOAK_03866 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HLNCHOAK_03867 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HLNCHOAK_03868 1.5e-151 yqcI S YqcI/YcgG family
HLNCHOAK_03869 2.1e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HLNCHOAK_03870 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HLNCHOAK_03871 3.4e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLNCHOAK_03872 1.4e-107 tmrB S AAA domain
HLNCHOAK_03873 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HLNCHOAK_03874 1.2e-143 yafE Q ubiE/COQ5 methyltransferase family
HLNCHOAK_03875 1.9e-175 oxyR3 K LysR substrate binding domain
HLNCHOAK_03876 4.2e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HLNCHOAK_03877 2.9e-145 ycgL S Predicted nucleotidyltransferase
HLNCHOAK_03878 5.1e-170 ycgM E Proline dehydrogenase
HLNCHOAK_03879 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HLNCHOAK_03880 7.6e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLNCHOAK_03881 2.3e-226 ycgP QT COG2508 Regulator of polyketide synthase expression
HLNCHOAK_03883 0.0 S Protein of unknown function (DUF1430)
HLNCHOAK_03884 1.8e-100 V ATPases associated with a variety of cellular activities
HLNCHOAK_03885 1.2e-144 ycgQ S membrane
HLNCHOAK_03886 1.2e-139 ycgR S permeases
HLNCHOAK_03887 3.6e-157 I alpha/beta hydrolase fold
HLNCHOAK_03888 2.5e-186 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HLNCHOAK_03889 3e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HLNCHOAK_03890 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HLNCHOAK_03891 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HLNCHOAK_03892 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLNCHOAK_03893 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HLNCHOAK_03894 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
HLNCHOAK_03895 3e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HLNCHOAK_03896 2.3e-107 yciB M ErfK YbiS YcfS YnhG
HLNCHOAK_03897 2e-227 yciC S GTPases (G3E family)
HLNCHOAK_03898 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
HLNCHOAK_03899 1.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HLNCHOAK_03901 2e-74 yckC S membrane
HLNCHOAK_03902 9.6e-50 yckD S Protein of unknown function (DUF2680)
HLNCHOAK_03903 4.1e-45 K MarR family
HLNCHOAK_03904 9.3e-24
HLNCHOAK_03905 2.7e-121 S AAA domain
HLNCHOAK_03906 9.5e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HLNCHOAK_03907 1.6e-67 nin S Competence protein J (ComJ)
HLNCHOAK_03908 3.5e-71 nucA M Deoxyribonuclease NucA/NucB
HLNCHOAK_03909 1.9e-178 tlpC 2.7.13.3 NT chemotaxis protein
HLNCHOAK_03910 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HLNCHOAK_03911 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HLNCHOAK_03912 1.3e-63 hxlR K transcriptional
HLNCHOAK_03913 2.1e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HLNCHOAK_03914 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HLNCHOAK_03915 1.2e-84 gerD
HLNCHOAK_03916 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HLNCHOAK_03917 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HLNCHOAK_03918 9.7e-66 ybaK S Protein of unknown function (DUF2521)
HLNCHOAK_03919 2.4e-144 ybaJ Q Methyltransferase domain
HLNCHOAK_03920 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HLNCHOAK_03921 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLNCHOAK_03922 4.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLNCHOAK_03923 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLNCHOAK_03924 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLNCHOAK_03925 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLNCHOAK_03926 3.6e-58 rplQ J Ribosomal protein L17
HLNCHOAK_03927 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLNCHOAK_03928 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLNCHOAK_03929 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLNCHOAK_03930 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HLNCHOAK_03931 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLNCHOAK_03932 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HLNCHOAK_03933 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLNCHOAK_03934 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLNCHOAK_03935 1.8e-72 rplO J binds to the 23S rRNA
HLNCHOAK_03936 1.9e-23 rpmD J Ribosomal protein L30
HLNCHOAK_03937 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLNCHOAK_03938 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLNCHOAK_03939 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLNCHOAK_03940 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLNCHOAK_03941 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLNCHOAK_03942 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLNCHOAK_03943 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLNCHOAK_03944 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLNCHOAK_03945 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLNCHOAK_03946 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HLNCHOAK_03947 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLNCHOAK_03948 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLNCHOAK_03949 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLNCHOAK_03950 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLNCHOAK_03951 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLNCHOAK_03952 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLNCHOAK_03953 3e-105 rplD J Forms part of the polypeptide exit tunnel
HLNCHOAK_03954 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLNCHOAK_03955 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HLNCHOAK_03956 1.9e-183 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HLNCHOAK_03957 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLNCHOAK_03958 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLNCHOAK_03959 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLNCHOAK_03960 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLNCHOAK_03961 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HLNCHOAK_03962 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLNCHOAK_03963 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLNCHOAK_03964 3.1e-107 rsmC 2.1.1.172 J Methyltransferase
HLNCHOAK_03965 7.4e-43 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLNCHOAK_03966 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLNCHOAK_03967 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLNCHOAK_03968 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLNCHOAK_03969 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HLNCHOAK_03970 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLNCHOAK_03971 4.4e-115 sigH K Belongs to the sigma-70 factor family
HLNCHOAK_03972 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HLNCHOAK_03973 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLNCHOAK_03974 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLNCHOAK_03975 7.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HLNCHOAK_03976 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HLNCHOAK_03977 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLNCHOAK_03978 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HLNCHOAK_03979 3.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HLNCHOAK_03980 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HLNCHOAK_03981 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HLNCHOAK_03982 2.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLNCHOAK_03983 0.0 clpC O Belongs to the ClpA ClpB family
HLNCHOAK_03984 1.1e-200 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HLNCHOAK_03985 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HLNCHOAK_03986 2.9e-76 ctsR K Belongs to the CtsR family
HLNCHOAK_03987 3.4e-31 csfB S Inhibitor of sigma-G Gin
HLNCHOAK_03988 1.8e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HLNCHOAK_03989 6.4e-202 yaaN P Belongs to the TelA family
HLNCHOAK_03990 1.3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HLNCHOAK_03991 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLNCHOAK_03992 1.1e-53 yaaQ S protein conserved in bacteria
HLNCHOAK_03993 1.5e-71 yaaR S protein conserved in bacteria
HLNCHOAK_03994 1.1e-181 holB 2.7.7.7 L DNA polymerase III
HLNCHOAK_03995 6.1e-146 yaaT S stage 0 sporulation protein
HLNCHOAK_03996 4.8e-31 yabA L Involved in initiation control of chromosome replication
HLNCHOAK_03997 3.6e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
HLNCHOAK_03998 2.1e-48 yazA L endonuclease containing a URI domain
HLNCHOAK_03999 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLNCHOAK_04000 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HLNCHOAK_04001 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLNCHOAK_04002 1.2e-143 tatD L hydrolase, TatD
HLNCHOAK_04003 2e-167 rpfB GH23 T protein conserved in bacteria
HLNCHOAK_04004 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLNCHOAK_04005 3.4e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLNCHOAK_04006 1.6e-136 yabG S peptidase
HLNCHOAK_04007 7.8e-39 veg S protein conserved in bacteria
HLNCHOAK_04008 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLNCHOAK_04009 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HLNCHOAK_04010 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HLNCHOAK_04011 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HLNCHOAK_04012 5.6e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLNCHOAK_04013 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLNCHOAK_04014 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HLNCHOAK_04015 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLNCHOAK_04016 2.4e-39 yabK S Peptide ABC transporter permease
HLNCHOAK_04017 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLNCHOAK_04018 1.5e-92 spoVT K stage V sporulation protein
HLNCHOAK_04019 1.1e-281 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLNCHOAK_04020 3.3e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HLNCHOAK_04021 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HLNCHOAK_04022 1.5e-49 yabP S Sporulation protein YabP
HLNCHOAK_04023 9.5e-107 yabQ S spore cortex biosynthesis protein
HLNCHOAK_04024 1.1e-44 divIC D Septum formation initiator
HLNCHOAK_04025 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HLNCHOAK_04028 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HLNCHOAK_04029 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HLNCHOAK_04030 6.3e-185 KLT serine threonine protein kinase
HLNCHOAK_04031 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLNCHOAK_04032 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HLNCHOAK_04033 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLNCHOAK_04034 1.3e-145 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HLNCHOAK_04035 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLNCHOAK_04036 6.5e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HLNCHOAK_04037 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HLNCHOAK_04038 9.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLNCHOAK_04039 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HLNCHOAK_04040 1.3e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HLNCHOAK_04041 1e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HLNCHOAK_04042 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLNCHOAK_04043 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLNCHOAK_04044 4.1e-30 yazB K transcriptional
HLNCHOAK_04045 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLNCHOAK_04046 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HLNCHOAK_04047 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HLNCHOAK_04048 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HLNCHOAK_04049 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLNCHOAK_04050 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLNCHOAK_04051 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLNCHOAK_04052 3.6e-82 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLNCHOAK_04053 1.9e-95 yaaI Q COG1335 Amidases related to nicotinamidase
HLNCHOAK_04054 4e-213 yaaH M Glycoside Hydrolase Family
HLNCHOAK_04055 1e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HLNCHOAK_04056 8.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HLNCHOAK_04057 1.3e-09
HLNCHOAK_04058 8.1e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLNCHOAK_04059 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HLNCHOAK_04060 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HLNCHOAK_04061 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HLNCHOAK_04062 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HLNCHOAK_04063 2.6e-180 yaaC S YaaC-like Protein
HLNCHOAK_04064 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLNCHOAK_04065 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLNCHOAK_04066 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLNCHOAK_04067 8e-238 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLNCHOAK_04077 2e-08
HLNCHOAK_04079 1.8e-59
HLNCHOAK_04083 1.3e-09
HLNCHOAK_04084 2e-08
HLNCHOAK_04087 7.8e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)