ORF_ID | e_value | Gene_name | EC_number | CAZy | COGs | Description |
---|---|---|---|---|---|---|
PDKGFFGC_00001 | 3.4e-31 | csfB | S | Inhibitor of sigma-G Gin | ||
PDKGFFGC_00002 | 4.7e-103 | xpaC | S | 5-bromo-4-chloroindolyl phosphate hydrolysis protein | ||
PDKGFFGC_00003 | 4.5e-203 | yaaN | P | Belongs to the TelA family | ||
PDKGFFGC_00004 | 1.1e-275 | adiA | 4.1.1.17, 4.1.1.18, 4.1.1.19 | E | Orn Lys Arg decarboxylase | |
PDKGFFGC_00005 | 3.6e-114 | tmk | 2.7.4.9 | F | Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis | |
PDKGFFGC_00006 | 2.2e-54 | yaaQ | S | protein conserved in bacteria | ||
PDKGFFGC_00007 | 1.5e-71 | yaaR | S | protein conserved in bacteria | ||
PDKGFFGC_00008 | 2.2e-182 | holB | 2.7.7.7 | L | DNA polymerase III | |
PDKGFFGC_00009 | 2.1e-146 | yaaT | S | stage 0 sporulation protein | ||
PDKGFFGC_00010 | 4.8e-31 | yabA | L | Involved in initiation control of chromosome replication | ||
PDKGFFGC_00011 | 9.4e-138 | yabB | 2.1.1.223 | S | Conserved hypothetical protein 95 | |
PDKGFFGC_00012 | 1.5e-49 | yazA | L | endonuclease containing a URI domain | ||
PDKGFFGC_00013 | 4.3e-158 | rsmI | 2.1.1.198 | H | Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA | |
PDKGFFGC_00014 | 8.8e-44 | abrB | K | COG2002 Regulators of stationary sporulation gene expression | ||
PDKGFFGC_00015 | 0.0 | metG | 6.1.1.10, 6.1.1.20 | J | Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation | |
PDKGFFGC_00016 | 1.8e-144 | tatD | L | hydrolase, TatD | ||
PDKGFFGC_00017 | 4.3e-194 | rpfB | GH23 | T | protein conserved in bacteria | |
PDKGFFGC_00018 | 8.4e-99 | rnmV | 3.1.26.8 | J | Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step | |
PDKGFFGC_00019 | 2.4e-156 | ksgA | 2.1.1.182 | J | Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits | |
PDKGFFGC_00020 | 3.3e-137 | yabG | S | peptidase | ||
PDKGFFGC_00021 | 7.8e-39 | veg | S | protein conserved in bacteria | ||
PDKGFFGC_00022 | 8.3e-27 | sspF | S | DNA topological change | ||
PDKGFFGC_00023 | 4.1e-161 | ispE | 2.1.1.182, 2.7.1.148 | I | Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol | |
PDKGFFGC_00024 | 2.6e-152 | purR | 2.4.2.22, 2.4.2.7 | F | pur operon repressor | |
PDKGFFGC_00025 | 3.8e-63 | yabJ | 3.5.99.10 | J | translation initiation inhibitor, yjgF family | |
PDKGFFGC_00026 | 4.6e-48 | spoVG | D | Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation | ||
PDKGFFGC_00027 | 6.6e-230 | glmU | 2.3.1.157, 2.7.7.23 | M | Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain | |
PDKGFFGC_00028 | 9.4e-175 | prs | 2.7.6.1 | F | Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) | |
PDKGFFGC_00029 | 3.9e-97 | ctc | J | This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance | ||
PDKGFFGC_00030 | 8e-105 | pth | 3.1.1.29 | J | The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis | |
PDKGFFGC_00031 | 2.4e-39 | yabK | S | Peptide ABC transporter permease | ||
PDKGFFGC_00032 | 0.0 | mfd | L | Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site | ||
PDKGFFGC_00033 | 1.5e-92 | spoVT | K | stage V sporulation protein | ||
PDKGFFGC_00034 | 2.4e-287 | yabM | S | COG2244 Membrane protein involved in the export of O-antigen and teichoic acid | ||
PDKGFFGC_00035 | 2.7e-245 | mazG | 3.6.1.66, 3.6.1.9 | S | COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like | |
PDKGFFGC_00036 | 1.1e-37 | yabO | J | COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) | ||
PDKGFFGC_00037 | 1.5e-49 | yabP | S | Sporulation protein YabP | ||
PDKGFFGC_00038 | 3.9e-108 | yabQ | S | spore cortex biosynthesis protein | ||
PDKGFFGC_00039 | 1.1e-44 | divIC | D | Septum formation initiator | ||
PDKGFFGC_00040 | 8.5e-58 | yabR | J | RNA binding protein (contains ribosomal protein S1 domain) | ||
PDKGFFGC_00043 | 0.0 | spoIIE | 3.1.3.16, 3.1.3.3 | KT | stage II sporulation protein E | |
PDKGFFGC_00044 | 1.5e-124 | yabS | S | protein containing a von Willebrand factor type A (vWA) domain | ||
PDKGFFGC_00045 | 6.7e-187 | KLT | serine threonine protein kinase | |||
PDKGFFGC_00046 | 3.5e-274 | tilS | 2.4.2.8, 6.3.4.19 | D | Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine | |
PDKGFFGC_00047 | 7.9e-94 | hpt | 2.4.2.8, 6.3.4.19 | F | Belongs to the purine pyrimidine phosphoribosyltransferase family | |
PDKGFFGC_00048 | 0.0 | ftsH | O | Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins | ||
PDKGFFGC_00049 | 1.5e-146 | coaX | 2.7.1.33 | F | Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis | |
PDKGFFGC_00050 | 2.9e-162 | hslO | O | Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress | ||
PDKGFFGC_00051 | 3.1e-153 | yacD | 5.2.1.8 | O | peptidyl-prolyl isomerase | |
PDKGFFGC_00052 | 8.9e-170 | cysK | 2.5.1.47 | E | Belongs to the cysteine synthase cystathionine beta- synthase family | |
PDKGFFGC_00053 | 4.7e-271 | pabB | 2.6.1.85 | EH | Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia | |
PDKGFFGC_00054 | 1.5e-106 | pabA | 2.6.1.85, 4.1.3.27 | EH | Anthranilate synthase | |
PDKGFFGC_00055 | 1.6e-168 | pabC | 2.6.1.42, 4.1.3.38 | EH | 4-amino-4-deoxychorismate lyase | |
PDKGFFGC_00056 | 2.6e-160 | folP | 2.5.1.15, 2.7.6.3 | H | Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives | |
PDKGFFGC_00057 | 8.2e-63 | folB | 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 | H | Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin | |
PDKGFFGC_00058 | 2.7e-88 | folK | 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 | H | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | |
PDKGFFGC_00059 | 4.1e-30 | yazB | K | transcriptional | ||
PDKGFFGC_00060 | 3.7e-190 | dus | J | Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines | ||
PDKGFFGC_00061 | 1.3e-287 | lysS | 6.1.1.6 | J | Belongs to the class-II aminoacyl-tRNA synthetase family | |
PDKGFFGC_00062 | 2.7e-182 | yaaC | S | YaaC-like Protein | ||
PDKGFFGC_00063 | 1.8e-273 | guaB | 1.1.1.205 | F | Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | |
PDKGFFGC_00064 | 5.2e-248 | dacA | 3.4.16.4 | M | Belongs to the peptidase S11 family | |
PDKGFFGC_00065 | 2.2e-157 | pdxS | 4.3.3.6 | H | Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively | |
PDKGFFGC_00066 | 8e-108 | pdxT | 4.3.3.6 | H | Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS | |
PDKGFFGC_00067 | 4.3e-207 | serS | 6.1.1.11 | J | Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) | |
PDKGFFGC_00068 | 1.3e-09 | |||||
PDKGFFGC_00069 | 2.2e-122 | dck | 2.7.1.113, 2.7.1.74, 2.7.1.76 | F | Deoxycytidine kinase | |
PDKGFFGC_00070 | 3.2e-115 | dgk | 2.7.1.113, 2.7.1.74, 2.7.1.76 | F | Deoxyguanosine kinase | |
PDKGFFGC_00071 | 5.6e-215 | yaaH | M | Glycoside Hydrolase Family | ||
PDKGFFGC_00072 | 2.4e-98 | yaaI | Q | COG1335 Amidases related to nicotinamidase | ||
PDKGFFGC_00073 | 1e-84 | tadA | 3.5.4.1, 3.5.4.3, 3.5.4.33 | FJ | Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) | |
PDKGFFGC_00074 | 0.0 | dnaX | 2.7.7.7 | L | DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity | |
PDKGFFGC_00075 | 5.3e-37 | yaaK | S | Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection | ||
PDKGFFGC_00076 | 3.9e-110 | recR | L | May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO | ||
PDKGFFGC_00077 | 7.9e-32 | yaaL | S | Protein of unknown function (DUF2508) | ||
PDKGFFGC_00078 | 3.7e-36 | bofA | S | Sigma-K factor-processing regulatory protein BofA | ||
PDKGFFGC_00079 | 0.0 | Q | Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall | |||
PDKGFFGC_00080 | 0.0 | Q | Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall | |||
PDKGFFGC_00081 | 0.0 | Q | Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall | |||
PDKGFFGC_00082 | 3.4e-39 | S | COG NOG14552 non supervised orthologous group | |||
PDKGFFGC_00087 | 2e-08 | |||||
PDKGFFGC_00090 | 0.0 | gyrA | 5.99.1.3 | L | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | |
PDKGFFGC_00091 | 0.0 | gyrB | 5.99.1.3 | L | A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner | |
PDKGFFGC_00092 | 1.8e-37 | yaaB | S | Domain of unknown function (DUF370) | ||
PDKGFFGC_00093 | 1.4e-206 | recF | L | it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP | ||
PDKGFFGC_00094 | 2.4e-33 | yaaA | S | S4 domain | ||
PDKGFFGC_00095 | 6.1e-205 | dnaN | 2.7.7.7 | L | Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria | |
PDKGFFGC_00096 | 6e-252 | dnaA | L | it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids | ||
PDKGFFGC_00097 | 3e-54 | rnpA | 3.1.26.5 | J | RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme | |
PDKGFFGC_00098 | 1.7e-118 | yidC | U | Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins | ||
PDKGFFGC_00099 | 6.5e-108 | jag | S | single-stranded nucleic acid binding R3H | ||
PDKGFFGC_00100 | 3.1e-251 | mnmE | S | Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 | ||
PDKGFFGC_00101 | 0.0 | gidA | D | NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 | ||
PDKGFFGC_00102 | 2.2e-131 | rsmG | 2.1.1.170 | J | Specifically methylates the N7 position of guanine in position 535 of 16S rRNA | |
PDKGFFGC_00103 | 1.9e-150 | noc | D | Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage | ||
PDKGFFGC_00104 | 1.5e-74 | S | Bacterial PH domain | |||
PDKGFFGC_00105 | 2.2e-134 | soj | D | COG1192 ATPases involved in chromosome partitioning | ||
PDKGFFGC_00106 | 2.1e-149 | spo0J | K | Belongs to the ParB family | ||
PDKGFFGC_00107 | 1.6e-111 | yyaC | S | Sporulation protein YyaC | ||
PDKGFFGC_00108 | 8.1e-177 | yyaD | S | Membrane |
eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)